Podcasts about reading uk

In this episode, Xavier Bonilla has a dialogue with Burak Kadercan about territory and nation states. They define territory and nation states, discuss empire, healthy nationalism, and ethnic groups in territories. They also define borders and discuss Westphalia, mosaic and monolithic order, Ottoman empire, war and conflict, Russia and Ukraine conflict, and many more topics. Burak Kadercan is Associate Professor of Strategy and Policy at the United States Naval War College in Newport, Rhode Island. He has his Ph.D. in Political Science from the University of Chicago. He was an inaugural fellow at the Center for Strategic Studies, The Fletcher School, Tufts University. He was also a Lecturer in International Relations at the University of Reading (UK) and Assistant Professor in International Relations and coordinator for the Master Program in International Security at Institut Barcelona D'Estudis Internacionals (IBEI). He is also Senior Associate at the Center on Irregular Warfare and Armed Groups (CIWAG). His main interest are in territoriality, international security, and state-formation. He is the author of Shifting Grounds: The Social Origins of Territorial Conflict.Website: http://www.burakadercan.com/ Get full access to Converging Dialogues at convergingdialogues.substack.com/subscribe

This episode was recorded during the 7th Gathering of the ParlAmericas Parliamentary Network on Climate Change and the 15th Gathering of the Parliamentary Network on Gender Equality, A Food Secure Future: Building People and Planet-centred Strategies, held in September 2023, in Mexico City, Mexico.In the session, moderated by Member of Parliament Tamika Davis (Jamaica), the panellist, Nadia Manning-Thomas, Planning and Coordination Specialist and Thematic Lead on Climate Change, Disaster Risk Resilience and Humanitarian Action at UN Women Multi-Country Office-Caribbean in Barbados, focused on the main challenges women face related to food security and sovereignty.Nadia Manning-Thomas works for the UN Women Multi-Country Office for the Caribbean as a Planning and Coordination Specialist for Barbados and the Organization of Eastern Caribbean States and as a specialist on Climate Change, Disaster Risk Resilience and Humanitarian Action across the MCO's 22 English and Dutch speaking countries of the Caribbean. Nadia has a BA in Anthropology and Environmental Studies from Grinnell College (USA) and an MSc in Environment and Development from the University of Reading (UK). A national of Barbados, Nadia has over 25 years of experience spanning Africa, Asia, the Middle East, and the Caribbean with a career focused on researching and implementing development pathways; with a particular focus on well-coordinated and collaborative human-centered development, agriculture and food systems, climate resilience and adaptation, and knowledge sharing and capacity development.UN Women Multi-Country Office for the Caribbean is the United Nations entity dedicated to gender equality and the empowerment of women in the region, supporting governments and civil society to design laws, policies, programs and services needed to ensure that the standards are effectively implemented and truly benefit women and girls as well as making women's equal participation in all aspects of life a reality.

Nella rubrica Contemporaneamente, Mariantonietta Firmani intervista Federico Faloppa linguista e Laura Caponnetto filosofa. L'intervista è in Contemporaneamente di Mariantonietta Firmani, il podcast divulgato da Artribune.com e Parallelo42.it In Contemporaneamente podcast trovate incontri tematici con autorevoli interpreti del contemporaneo tra arte e scienza, letteratura, storia, filosofia, architettura, cinema e molto altro. Per approfondire questioni auliche ma anche cogenti e futuribili. Dialoghi straniati per accedere a nuove letture e possibili consapevolezze dei meccanismi correnti: tra locale e globale, tra individuo e società, tra pensiero maschile e pensiero femminile, per costruire una visione ampia, profonda ed oggettiva della realtà. Federico Faloppa e Laura Caponnetto ci raccontano della grande varietà linguistica, e dello studio filosofico dei linguaggi. 7000 lingue nel mondo, alcune a rischio estinzione, dove il linguaggio è un ecosistema che racconta umani e territori. Quindi, cruciale è il dibattito tra la ricerca di una lingua comune e la necessità di salvare le molteplicità locali. La filosofia del linguaggio si muove dal significato dei nomi, alle ingiustizie illocutorie, all'innovazione concettuale che riempie di nuovo senso la percezione del mondo. E ancora, ci parlano di fallaci retoriche, argomentazioni deboli, narrazioni distorte delle migrazioni, e molto altro. GUARDA IL VIDEO!! https://youtu.be/PCYF4YrOSpU BREVI NOTE BIOGRAFICHE DEGLI AUTORI Federico Falloppa linguista, ordinario di Italian Studies and linguistics, Dipartimento di Languages and Cultures, all'Università di Reading (UK), dove dirige il Corso di Studi Italiani. Laurea in Lettere e Filosofia all'Università di Torino, Dottorato alla Royal Holloway, Università di Londra, ha insegnato nelle università di Birmingham, Granada, Londra e Torino.È anche PhD esaminatore esterno a Birmingham, Leeds, Cardiff e Sheffield; è anche editor e consulente presso enti pubblici e organizzazioni non governative. Le sue ricerche si rivolgono soprattutto allo studio degli stereotipi etnici, migrazioni e rifugiati, costruzione linguistica della diversità, politica linguistica, letteratura italiana contemporanea. Tra i molti progetti di ricerca è co-investigatore in "MultiMind", Marie Skłodowska-Curie funded Innovative Training Networks, Horizon 2020 3,7 milioni di euro. Inoltre è anche rete internazionale "ProLanguage” finanziata da ESRC (Economic and Social Research Council), 131.000 euro. Autore di numerose pubblicazioni tra cui: “Lessico e alterità. La formulazione del diverso”, 2000; “Parole contro. La rappresentazione del diverso nella lingua italiana e nei dialetti”, 2004. Ed anche: “#Odio. Manuale di resistenza alla violenza delle parole”, 2020. Ultimo: “Sbiancare un etiope. La costruzione di un immaginario razzista”, 2022; e molto altro. Laura Caponetto è Sarah Smithson Research Fellow presso il Newnham College, University of Cambridge, già ricercatrice alla Facoltà di Filosofia dell'Università Vita-Salute San Raffaele, Milano. È anche docente a contratto nel Dipartimento di Scienze Politiche e Sociali dell'Università di Pavia. La sua ricerca verte sulla filosofia sociale del linguaggio, disciplina al crocevia tra filosofia del linguaggio, filosofia sociale e politica, e studi di genere.Sono due i temi principali della sua produzione scientifica. Primo: l‘ingiustizia discorsiva, quando l'identità sociale influisce negativamente sulle possibilità comunicative; secondo: le strategie per “disfare” col linguaggio, ovvero ritrattare dichiarazioni, cancellare promesse, ritirare accuse. Ha pubblicato articoli su prestigiose riviste internazionali, come Analysis, Synthese, Rivista italiana di filosofia del linguaggio. È tra le 100 esperte in storia e filosofia per il progetto “100 donne contro gli stereotipi” condotto dall'Osservatorio di Pavia e l'associazione Gi.U.Li.A giornaliste. Infine, è tra le socie fondatrici di SWIP Italia – Società italiana per le donne in filosofia.

This week Robert is joined by Ed Hawkins, Professor of Climate Science at the University of Reading (UK). The subject of our Climate is always one that'll start a good debate, and in this fascinating podcast Robert discusses the Decarbonisation Problem with Professor Hawkins, what we can do to slow rising temperatures, and what can be learnt from the past. Don't forget to SUBSCRIBE to the Everything Electric SHOW channel and help us reach 100k subscribers! Everything Electric Show: https://www.youtube.com/@EverythingElectricShow Fully Charged Show: https://www.youtube.com/@fullychargedshow Visit our next event, Fully Charged LIVE Europe in Amsterdam: https://fullycharged.live/ Support our StopBurningStuff campaign: https://www.patreon.com/STOPBurningStuff Become a Fully Charged SHOW Patreon: https://www.patreon.com/fullychargedshow Buy the Fully Charged Guide to Electric Vehicles & Clean Energy : https://buff.ly/2GybGt0 Subscribe for episode alerts and the Fully Charged newsletter: https://fullycharged.show/zap-sign-up/ Follow us on Instagram: https://instagram.com/fullychargedshow      

In this conversation with leadership expert Peter Hawkins we explore the role of coaching in these times, the limits of AI coaching, wide-angled empathy, systemic coaching and helping organizations embrace the unknown. Peter Hawkins is Professor of Leadership at Henley Business School University of Reading UK and Emeritus Chairman of Bath Consultancy Group, where for the last 25 years he has been helping organizations in many parts of the world connect their strategic change, their organizational culture and their leadership development. He has written extensively about leadership, leadership teams, coaching and supervision. He is visiting professor at the universities of Bath and Oxford Brookes, and chairs Renewal Associates and Connect Assist. Visit coachesrising.com to see our acclaimed online coach trainings and other offerings.

1. The (evil?) architect of The Great Reset - Sorelle Amore Finance (10:46) *Who is Klaus Schwab, really? I'll be trying to bring a more balanced perspective to the answer to that question. Because when it comes to the leader of the WEF, it seems like most of the information that's out there is pushing a very one-sided view. 2. United Nations announces Klaus Schwab of the World Economic Forum and UN General Secretary Antonio Guterres have signed an agreement to ‘accelerate' Agenda 2030 (0:30) 3. World Economic Forum | Strategic Intelligence 4. If I Were the Devil: Paul Harvey (2:47) * Paul Harvey Aurandt was an American radio broadcaster for ABC News Radio. He broadcast News and Comment on mornings and mid-days on weekdays and at noon on Saturdays and also his famous The Rest of the Story segments. From 1951 to 2008, his programs reached as many as 24 million people per week.  5. Gun Control and The Vaule Of Life (8:09)   Vitamin B6 Supplements In High Doses Can Calm Anxiety, Depression   University of Reading (UK), July 18, 2022 Taking high-dose vitamin B6 supplements may help to reduce feelings of anxiety and depression, a new study reveals. Researchers from the University of Reading in England report that young adults taking a dose 50 times the recommended daily dose reported feeling less anxious and depressed after a month. Vitamin B6 increases the body's production of GABA (Gamma-Aminobutyric Acid), a chemical that blocks impulses between nerve cells in the brain. Vitamin B6 is found naturally in a variety of foods, including salmon, tuna, chickpeas, and bananas.  Vitamin B6 helps the body produce a specific chemical messenger that inhibits impulses in the brain, and this study links this calming effect with reduced anxiety among the participants.” The study provides evidence lacking in previous studies as to what exactly drives the stress-reducing effects of marmite and multivitamins. More than 300 participants took either a placebo or Vitamin B6 or B12 supplements at 50 times the recommended amount – around 70mg. Each participant took one tablet a day with food. Vitamin B12 had little effect compared to the placebo, but B6 showed a statistically reliable difference. The team also detected subtle but harmless changes in visual performance, consistent with controlled levels of brain activity. Health officials in the United Kingdom recommend that people do not take too high a dose – more than 200mg a day – as it can lead to a loss of feeling in the arms and legs. In a few cases, this has become permanent in people who have taken very large doses for several months.   “Many foods, including tuna, chickpeas and many fruits and vegetables, contain Vitamin B6. However, the high doses used in this trial suggest that supplements would be necessary to have a positive effect on mood,” Dr. Field continues. “It is important to acknowledge that this research is at an early stage and the effect of Vitamin B6 on anxiety in our study was quite small compared to what you would expect from medication. However, nutrition-based interventions produce far fewer unpleasant side effects than drugs, and so in the future people might prefer them as an intervention.   Study Ranks Healthiest ‘Powerhouse' Vegetables, Which is #1?  William Paterson University, July 14   Research from William Paterson University attempted to rank fruits and vegetables according to the amount of nutrition within. In all, they list 41 “powerhouse” vegetables and fruits, scoring them according to the presence of 17 nutrients. The produce was scored by the presence of: fiber, potassium, protein, calcium, folate, vitamin D, vitamin A, vitamin B12, and more.   To make the study's “powerhouse” list, the researchers calculated each fruit or vegetable's “nutrient density” score based on the percentage of your daily need for each nutrient the food provides. (The study assumed a 2,000 calorie per day diet and 100 grams of each food.) The scores were capped to ensure that a fruit or vegetable that provides a huge amount of just a single nutrient wouldn't receive a disproportionately high overall score.” So, which earned the top spot? Super easy-to-grow watercress. Watercress scored an even 100, with Chinese cabbage closest behind with a score of 91.99. In third place was chard (89.27), followed by beet greens (87.08), spinach (86.43), and chicory (73.36).  Fruits scored lower, with red pepper at the top (41.26), followed by pumpkin (32.23), tomatoes (20.37), and lemons (18.72). Many of these are surprising considering they aren't the “superfruits” we are accustomed to hearing about. But, that's largely because of the nutrients measured in this study. Fruits like blueberries, that are considered healthiest by many, earn that spot because of their antioxidant levels. This study didn't capture the concentration of antioxidants, however.       Can listening to the Beatles improve your memory? New research says music just might stir the brain Northeastern University, July 19, 2022 When Paul McCartney wrote "Get Back," he never would have predicted how useful or relevant the song would become for music therapists. The song's refrain—"Get back to where you once belonged"—might as well be a therapist encouraging a dementia patient to recall a distant memory. In new research, Psyche Loui, an associate professor of music, is attempting to do exactly that. Published in Scientific Reports, Loui found that for older adults who listened to some of their favorite music, including The Beatles, connectivity in the brain increased. Specifically, Loui—and her multi-disciplinary team of music therapists, neurologists and geriatric psychiatrists—discovered that music bridged the gap between the brain's auditory system and reward system, the area that governs motivation. The researchers had a group of older adults between the ages of 54 and 89 from the Boston area listen to a playlist for an hour every day for eight weeks and journal about their response to the music afterward. Loui and the team would scan the participants' brains before and after listening in order to measure their neurological response. Playlists were highly personalized and featured a combination of the participants' self-selected songs, which ranged from The Beatles to Bruce Springsteen, and a preselected mix of classical pieces, pop and rock songs and new compositions.The most important lesson that we learned from the music therapist was that there is no one-size-fits-all for what kind of music works best," Loui said. What the researchers found was striking: Music was essentially creating an auditory channel directly to the medial prefrontal cortex, the brain's reward center. Notably, the medial prefrontal cortex "is one of the areas to lose its activity and functional connectivity in aging adults, especially in folks with dementia," Loui said. Music that was both familiar and well-liked tended to activate the auditory and reward areas more. However, the music that participants selected themselves provided an even stronger connection between these two areas of the brain.   DHA omega-3 linked to ‘significantly improved periodontal outcomes': Harvard data Harvard University, July 14 ,2022 Scientists from Harvard report that supplementation with DHA (docosahexaenoic acid) omega-3 may improve periodontal outcomes in people with periodontitis. Periodontitis is a serious gum infection that destroys the soft tissue and bone supporting the teeth. It is reportedly the second most common disease worldwide, with 30–50% of the US population suffering from it. Data published in the Journal of Dental Research indicated that DHA supplementation was associated with a decreased the average depth of the pockets between the teeth and the gums, and the gingival index, which is used to assess the extent of gum disease. In addition, inflammatory biomarkers in the gum tissue were significantly reduced. Participants were randomly assigned to receive either 2,000 mg per day of DHA or placebo (soy/corn oil) for three months. All of the participants also received 81 mg per day of aspirin. Results showed DHA levels in red blood cell membranes increased between 3.6% to 6.2%, whereas no such increases were observed in the placebo group. In addition to the improvements in pocket depth and gingival index, the researchers reported that levels of the inflammatory biomarkers C-reactive protein (CRP) and interleukin-1 beta (IL-1beta) decreased significantly in the DHA group.      This “Holy Herb' Shows Promise in Treating Alzheimer's Disease Yerba santa may also treat brain swelling in dementia patients Salk Institute, July 14, 2022 A shrub known as Yerba santa, dubbed “holy herb” in Spanish, appears to show promise in treating Alzheimer's disease, researchers say. It has the potential to reduce brain swelling in people with dementia.  Native to California, Yerba santa has long been used as a treatment for fevers, headaches, and other common ailments. But researchers at Salk's Cellular Neurobiology Laboratory believe it could be used to treat much more serious health problems. In fact, millions of dementia patients stand to benefit from the natural treatment, they claim. A molecule in the shrub called sterubin – the plant's most active component – could be the key to transforming millions of lives. The team found that sterubin had a significant anti-inflammatory effect on brain cells called microglia, which are involved in the development of Alzheimer's disease, among other ailments. The researchers further found that sterubin effectively removes iron. This is an important discovery, as iron contributes to nerve cell damage in the aging brain and neurodegenerative diseases. Sterubin was found to effectively reduce numerous causes of cell death in the nerve cells.   An inflammatory diet correlates with colorectal cancer risk The risk of developing colorectal cancer for individuals that follow a pro-inflammatory diet is two times higher than usual Bellvitge Biomedical Research Institute (Spain), July 15, 2022  Researchers from the Molecular Mechanisms and Experimental Therapy in Oncology program (Oncobell) of the Bellvitge Biomedical Research Institute (IDIBELL) and the Catalan Institute of Oncology (ICO) published in Nutrients the results of a multicenter study that unveils a correlation between inflammatory and antioxidant diets and the risk of developing colorectal and breast cancer.  "We have observed an association between the risk of developing colorectal cancer and the inflammatory potential of the diet. That is, the participants who followed an inflammatory diet had almost twice the risk of developing colorectal cancer, which is the 4th most frequent cancer worldwide", explains Dr. Mireia Obón. An inflammatory diet is usually characterized by the consumption of refined carbohydrates, red and processed meat, and saturated or trans fats. In an antioxidant diet, the consumption of vegetables, legumes, fruits and nuts predominates. "In this study we have focused on the role of diet, and specifically on its inflammatory and antioxidant capacity, as there is evidence that both chronic inflammation and oxidative stress influence the development of these two types of cancer", says Dr. Víctor Moreno. "Following a pro-inflammatory and pro-oxidant diet is a very important risk factor for colon cancer.  We should reorient our eating habits towards a Mediterranean diet, rich in fruits and vegetables, nuts, whole grains and healthy oils, such as olive oil and move away from a more pro-inflammatory diet", she argues.     OCCUPY PEACE & FREEDOM RALLY INFO Saturday, July 23 -- 2:00 pm Kingston, NY (at the historical 4 corners -- Crown and John Streets) Speakers: Gerald Celente Judge Andrew Napolitano Gary Null Scott Ritter Phil Giraldi (former CIA official) Live music, food and drink

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Grazia D. Santangelo is professor of Strategic and International Management at Copenhagen Business School and visiting professor at Henley Business School (UK). She earned her PhD in Economics at the University of Reading (UK) and, before joining Copenhagen Business School, held a Jean Monnet Chair in International Business at the University of Catania (Italy). She researches across the fields of international business, global strategy, and innovation. Her current research focuses on how firms deal with ethical issues and strategize about their intangibles around the globe; the evolution of firms' internationalization process; and the nexus between institutions, and firms' cross-border strategy. Her research has been published in leading academic journals such as Journal of International Business Studies, Journal of Economic Geography and Research Policy, and has been recognized by a number of international awards. She is Reviewing Editor of Journal of International Business Studies and a member of the editorial review board of Academy of Management Review. She also served as associated editor of Journal of International Management and Industry and Innovation. Grazia D. Santangelo is a Fellow of the European International Business Academy (EIBA), and elected member of the Executive Board of the Academy of Management (AOM) International Management (IM) division. She is Division Program Chair for AOM 2022. She served as Chair of the Research Committee of the AOM IM Division, representative-at-large of the Global Strategy Interest Group of the Strategic Management Society and as former EIBA president. Visit https://www.aib.world/frontline-ib/grazia-santangelo/ for the original video interview.  

Research shows healthy home cooking equals a healthy mind   Edith Cowan University (Australia), March 21, 2022   Research from Edith Cowan University (ECU) has found being confident in the kitchen is not only good for your taste buds: it's also good for your mental health. In total, 657 participants undertook the seven-week healthy cooking course. At the same time, ECU Institute for Nutrition Research academics measured the program's effect on participants' cooking confidence and self-perceived mental health, as well as their overall satisfaction around cooking and diet-related behaviors. Researchers found those who participated in the program saw significant improvements in general health, mental health and subjective vitality immediately after the program which remained six months after completing the course, when compared to the study's control group. Improvements in cooking confidence, the ability to easily change eating habits and overcome lifestyle barriers to healthy eating were also reported. Also, the mental health benefits were equal among participants who were overweight or obese, and those in a healthy weight range.   (NEXT)   Resveratrol can help to reduce inflammation, study finds   Georgia State University September 28, 2021    A component of red wine and grapes can help control inflammation induced by a bacterial pathogen that is linked to upper respiratory tract inflammatory diseases such as asthma, chronic obstructive pulmonary diseases (COPD) and middle ear infection (otitis media), according to a study by researchers at Georgia State University. The findings, published in the online journal Scientific Reports, identify a novel mechanism that resveratrol, a compound found naturally in some plant foods such as grapes, uses to alleviate inflammation in airway disease. The results suggest this compound could offer health benefits and be used to develop new, effective anti-inflammatory therapeutic agents. This study found for the first time that resveratrol decreases NTHi-induced expression of pro-inflammatory mediators in airway epithelial cells and in the lungs of mice by enhancing MyD88 short, a negative regulator of inflammatory signaling pathways. MyD88 short is considered a "brake pedal protein" because it can tightly control inflammation induced by this respiratory pathogen. It could be a critical target with significant therapeutic potential for suppressing inflammation associated with chronic airway disease.   (NEXT)    Psoriasis Linked to Low Vitamin E Levels   Dalian Medical College (China), March 21, 2022   Struggling with psoriasis? If so, you might need to increase your vitamin E intake. A meta-analysis published in December 2021 links this condition, along with other dermatologic grievances including acne and vitiligo, to low serum levels of vitamin E. Vitamin E has long been known to be essential for biochemical processes that are linked to psoriasis, including its involvement in immune system function, fatty acid metabolism and free-radical regulation. The results from this new analysis showed that the average person with psoriasis had 2.7-fold lower serum vitamin E levels compared to the average person in the controls, which was a stronger relationship than any of the skin disorders included.   (NEXT)   The secret to staying young: New research highlights power of life long exercise to keep muscles healthy   University of Copenhagen, March 21, 2022   Lifelong physical activity could protect against age-related loss of muscle mass and function, according to research published in The Journal of Physiology. Individuals aged 68 and above who were physically active throughout their life have healthier ageing muscle that has superior function and is more resistant to fatigue compared to inactive individuals, both young and old. This is the first study to investigate muscle, stem cell and nerve activity in humans. The researchers from University of Copenhagen, Denmark, found that elderly individuals who keep physically active throughout their adult life, whether by taking part in resistance exercise, ball games, racket sports, swimming, cycling, running and/or rowing had a greater number of muscle stem cells, otherwise known as satellite cells in their muscle. These cells are important for muscle regeneration and long-term growth and protect against nerve decay.   (NEXT)   Could a shot of orange juice boost brain power for men?   University of Reading (UK), September 23, 2021   Data published in the European Journal of Nutrition indicated that a 240 ml glass of the flavonoid-rich orange juice was associated with significantly improved scores for attention, executive function, and psychomotor speed in healthy middle-aged men without mild cognitive impairment six hours after consumption, compared with placebo. The researchers recruited 24 healthy men aged between 30 and 65 to participate in their randomized, double-blind, crossover study. The men were randomly assigned to consumer orange juice containing 272 mg of flavonoid or a calorie-matched placebo, with the interventions separated by two weeks. A battery of tests revealed that, compared to placebo, the flavonoid-rich orange juice was associated with significantly better performance on tests of executive function and psychomotor speed. Alertness was also reportedly improved following orange juice consumption.  

Magnet metals and rare earths miner Pensana has completed the front-end engineering design (FEED) for its UK-based Saltend rare earths production facility and its Angola-based Longonjo mine, reducing the capital expenditure (capex) costs of the projects and improving the operating profitability of both. A comprehensive value engineering and enhancement programme is well advanced and is expected to be reported in April, which is intended to result in a further reduction in the capital costs. Saltend is being designed as the UK's first rare earths processing facility and will produce 12 500 t/y of separated rare earth oxide, of which 4 500 t/y will be magnet metal rare earths – neodymium and praseodymium oxides, equivalent to about 5% of the projected world demand. Working alongside Wood Group's Perth (Australia), Reading (UK) and Johannesburg (South Africa) offices, project management and engineering company Paradigm Project Management (PPM) and Professional Cost Consultants (PCC) have managed to reduce the capital required to establish the projects. As such, the estimated capex for the projects has been reduced from $525-million to $494-million, with Saltend requiring $195-million and Longonjo needing $299-million. Although the cost of the Saltend refinery is set to increase from $190-million to $195-million, the mixed rare earth sulphate refinery cost is set to decrease from $152-million to $127-million; while the Longonjo concentrator will decrease from $134-million to $123-million. This leaves both the Longonjo mine and infrastructure costs, and the operational expenditures, unchanged at $49-million and $15/kg, respectively. This adjustment will result in Pensana producing higher revenues, increasing from the December 2021 estimate of $648-million a year for the first five years, to $705-million a year for the first five years. In turn, this will result in Pensana's earnings before interest, taxes, depreciation and amortisation increasing from a previous estimate of $413-million a year for the first five years, to $459-million a year for the same time period. In addition, the adjustment increases the project's net present value from $2.1-billion to $2.4-billion, and its internal rate of return from 50% to 61%. Considering these metrics, Pensana plans a payback period improvement on its investment from 2.3 years to 2.1 years. Pensana chairperson Paul Atherley says that reducing its capital and operating costs is a significant achievement by the technical team led by CEO Tim George, especially considering the inflationary pressures and supply chain constraints affecting projects globally. “The lower capital and strong operating margins will make the project attractive to our Financiers and are expected to lower the overall cost of finance,” says Atherley. Global supply chain constraints and inflationary pressures, which could have impacted both the Saltend and Longonjo projects, have been largely mitigated by the detailed enhancement and value engineering processes. Consequently, specific workstreams involving capital and operation cost savings are currently under way, including using spent acid regeneration to increase the recycling efficiency of the sulphuric acid plant. This will be integrated with off-gas from the calcining of concentrate at Longonjo, which is an important aspect of the process and constitutes a significant reduction of the carbon footprint through reduced reagent consumption. The piloting of a more cost-effective flotation concentrate calcining process offers a vendor alternative post-FEED, which would enable a significantly shorter lead time for fabrication and ease of installation at Longonjo. In addition, enhancement of Saltend's civil and earthworks for load-bearing structures is being undertaken alongside the completion of detailed geotechnical investigation, which will shorten the construction period and enable future affordable expansion into downstream activities associated with magnet metal p...

Today, a community's prosperity is linked to its ability to attract, retain, develop and mobilize talent. The future prosperity of Alberta is undoubtedly centered on people. The risk of young people leaving our province is real and extraordinarily complex. What drives young adults to “purchase” a city?  What are young Canadians' perceptions of Alberta? What does Alberta need to do to once again make Alberta a magnet for young adults? In this discussion, Dr. David Finch of Mount Royal University's CityXLab will review insights from a year-long study that examined the drivers of talent mobility in Alberta and across Canada.   Speaker: Dr. David J Finch                  Dr. David J. Finch holds a PhD in management and is an active educator, scholar and practitioner. He currently holds several academic appointments including as a Professor at Mount Royal University's Bissett School of Business, a Visiting Fellow at the Henley Business School at the University of Reading (UK), and the Gordon S. Lang School of Business and Economics at the University of Guelph. As a Senior Fellow at the Institute for Community Prosperity, Dr. Finch leads the Institute's CityXLab. This Lab explores the intersection between a city's learning, creative and active experiences; and its ability to attract, develop and retain human capital. Dr. Finch has authored over 50 scholarly papers and published in journals such as the Academy of Management Learning & Education, Journal of Business Ethics, Journal of Marketing Management, Journal of Sport Management and the Corporate Reputation Review. His most recent book Understanding the Active Economy and Emerging Research on the Value of Sports, Recreation, and Wellness (Finch & Legg) explores the value of the active economy to community. Prior to joining academia, Dr. Finch held progressively senior roles in areas of corporate strategy in Canada, the U.S and the U.K.

Can low temperature-aged garlic enhance exercise performance? Korea Univesity & National Institute of Agricultural Sciences (South Korea), October 8, 2021 Scientists from South Korea's National Institute of Agricultural Sciences and Korea University looked at aged garlic to see whether it could help reduce fatigue. To do this, they conducted a study on mice fed with a special low-temperature-aged garlic (LTAG). Their findings were published in the Journal of Medicinal Food. Testing the fatigue-fighting effects of low temperature-aged garlic The researchers chose to use LTAG because it lacked the pungent odor and spicy flavor of regular garlic, making it easier to use for animal testing. To create the LTAG, the researchers stored garlic in a sealed container, aging at 60 C for 60 days. The resulting LTAG was then peeled and pulverized, before being added to 200 milliliters of 70 percent ethanol (EtOH), which was then subjected to ultrasonic extraction three times. This 70 percent EtOH and LTAG extract was then concentrated under a vacuum at 45 C and then lyophilized to create a dry LTAG residue. After the creation of the LTAG, the researchers then separated mice into six groups. The first group was given a low dose of LTAG extract; the second was fed a high dose of LTAG extract; the third was given a low dose of garlic extract; and the fourth was given a high dose of garlic extract. The fifth and sixth groups consisted of normal mice that were given phosphate-buffered saline (PBS) instead of garlic. One of these control groups was made to exercise while the other group was not. The mice in the five groups were forced to run on a treadmill for four weeks. With each passing week, the amount of exercise the mice would have to do on the treadmills would increase. This was done by increasing both the speed that the mice had to run, and the amount of time they had to spend running. (Related: How to alleviate fatigue with herbal medicine.) After 28 days of treatment, five mice from each group were subjected to a final, exhaustive treadmill test. This test increased the treadmill speed from 15 meters per minute (m/min) to 40 m/min every 3 minutes. During this test, the running time was monitored until each mouse failed to follow the increase in speed on three consecutive occasions and lag occurred. At this point, the mouse's total running time was recorded. The effect of the LTAG on the levels of glucose, lactate dehydrogenase (LDH), free fatty acid (FFA) and lactate in the mice's blood. Following the final exercise, the mice were killed and blood samples were collected from them. In addition, the mice's gastrocnemius muscles were also isolated and frozen in liquid nitrogen for testing. LTAG treated mice demonstrated less fatigue Following the exhaustive running tests, the researchers found that the mice treated with LTAG extract were able to run for much longer than the control mice. Meanwhile, looking at the blood tests, they noted that the mice treated with LTAG extract exhibited lower levels of glucose, LDH, FFA and lactate. More importantly, the LTAG treated mice had increased amounts of glycogen and creatine kinase (CK) in their muscles. Glycogen storage is an important source of energy during exercise. It serves a central role in maintaining the body's glucose homeostasis by supplementing blood glucose. Because of this, glycogen is seen as an accurate marker for fatigue, with increased glycogel levels closely associated with improved endurance and anti-fatigue effects. CK, on the other hand, is known to be an accurate indicator of muscle damage. During muscle degeneration, muscle cells are dissolved and their contents enter the bloodstream. As a result, when muscle damage occurs, muscle CK comes out into the blood. As such, fatigue tends to lead to lower muscle CK levels and higher blood CK levels. Higher levels of glycogen and muscle CK in the LTAG treated mice indicated that they experienced less fatigue than the other groups. Based on these findings, the researchers believe that LTAG has potential for use as an anti-fatigue agent.       Mindfulness meditation helps preterm-born adolescents University of Geneva (Switzerland), October 7, 2021 Adolescents born prematurely present a high risk of developing executive, behavioral and socio-emotional difficulties. Now, researchers from Geneva University Hospitals (HUG) and the University of Geneva (UNIGE) have revealed that practicing mindfulness may help improve these various skills. The study, published in the journal Scientific Reports, suggests using mindfulness as a means of clinical intervention with adolescents, whether prematurely born or not. Several studies have already shown that very preterm (VPT) children and adolescents are at higher risk of exhibiting cognitive and socio-emotional problems that may persist into adulthood. To help them overcome the difficulties they face, researchers from the HUG and UNIGE have set up an intervention based on mindfulness, a technique known to have beneficial effects in these areas. Mindfulness consists in training the mind to focus on the present moment, concentrating on physical sensations, on breathing, on the weight of one's body, and even on one's feelings and thoughts, completely judgment-free. The mindfulness-based interventions generally take place in a group with an instructor along with invitations to practice individually at home. To accurately assess the effects of mindfulness, a randomized controlled trial was performed with young adolescents aged 10 to 14, born before 32 weeks gestational weeks. Scientists quickly found that mindfulness improves the regulation of cognitive, social and emotional functions, in other worlds, our brain's ability to interact with our environment. Indeed, it increases the ability to focus on the present—on thoughts, emotions and physical sensations, with curiosity and non-judgment. Thanks to this practice, adolescents improve their executive functions, i.e. the mental processes that enable us to control our behavior to successfully achieve a goal. As a result, young people find it easier to focus, manage and regulate their behavior and emotions in everyday life. For eight weeks, the young teens spent an hour and a half each week with two mindfulness instructors. They were further encouraged to practice mindfulness daily at home. Parents were also involved in this study. They were asked to observe their child's executive functions, for example the ability to regulate their emotions and attentional control, their relationships with others and their behavior. The adolescents also underwent a series of computerized tasks to assess their reactions to events. A comparison of their test results with a control group that did not practice mindfulness shows a positive impact of the intervention on the adolescents' everyday life and on their ability to react to new events. "Each teenager is unique, with their own strenghts and difficulties. Through their involvement in this study, our volunteers have contributed to show that mindfulness can help many young people to feel better, to refocus and to face the world, whether they were born preterm born or not," agree Dr. Russia Hà-Vinh Leuchter, a consultant in the Division of Development and Growth, Department of Paediatrics, Gynaecology and Obstetrics at Geneva University Hospitals, and Dr. Vanessa Siffredi, a researcher at the Child Development Laboratory at the Department of Paediatrics, Gynaecology and Obstetrics at the UNIGE Faculty of Medicine, two of the authors of this work. "However, while the practice of meditation can be a useful resource, it is important to be accompanied by well-trained instructors", they specify. The adolescents who took part in the program are now between 14 and 18 years. Scientists are currently evaluating the long-term effects of mindfulness-based intervention on their daily attention and stress. Furthermore, to validate their clinical data with neurobiological measurements, researchers are currently studying the effects of mindfulness on the brain using magnetic resonance imaging (MRI).   Iron deficiency in middle age is linked with higher risk of developing heart disease University Heart and Vasculature Centre Hamburg (Germany) 6 October 2021 Approximately 10% of new coronary heart disease cases occurring within a decade of middle age could be avoided by preventing iron deficiency, suggests a study published today in ESC Heart Failure, a journal of the European Society of Cardiology (ESC).1 “This was an observational study and we cannot conclude that iron deficiency causes heart disease,” said study author Dr. Benedikt Schrage of the University Heart and Vasculature Centre Hamburg, Germany. “However, evidence is growing that there is a link and these findings provide the basis for further research to confirm the results.” Previous studies have shown that in patients with cardiovascular diseases such as heart failure, iron deficiency was linked to worse outcomes including hospitalisations and death. Treatment with intravenous iron improved symptoms, functional capacity, and quality of life in patients with heart failure and iron deficiency enrolled in the FAIR-HF trial.2 Based on these results, the FAIR-HF 2 trial is investigating the impact of intravenous iron supplementation on the risk of death in patients with heart failure. The current study aimed to examine whether the association between iron deficiency and outcomes was also observed in the general population. The study included 12,164 individuals from three European population-based cohorts. The median age was 59 years and 55% were women. During the baseline study visit, cardiovascular risk factors and comorbidities such as smoking, obesity, diabetes and cholesterol were assessed via a thorough clinical assessment including blood samples. Participants were classified as iron deficient or not according to two definitions: 1) absolute iron deficiency, which only includes stored iron (ferritin); and 2) functional iron deficiency, which includes iron in storage (ferritin) and iron in circulation for use by the body (transferrin). Dr. Schrage explained: “Absolute iron deficiency is the traditional way of assessing iron status but it misses circulating iron. The functional definition is more accurate as it includes both measures and picks up those with sufficient stores but not enough in circulation for the body to work properly.” Participants were followed up for incident coronary heart disease and stroke, death due to cardiovascular disease, and all-cause death. The researchers analysed the association between iron deficiency and incident coronary heart disease, stroke, cardiovascular mortality, and all-cause mortality after adjustments for age, sex, smoking, cholesterol, blood pressure, diabetes, body mass index, and inflammation. Participants with a history of coronary heart disease or stroke at baseline were excluded from the incident disease analyses. At baseline, 60% of participants had absolute iron deficiency and 64% had functional iron deficiency. During a median follow-up of 13.3 years there were 2,212 (18.2%) deaths. Of these, a total of 573 individuals (4.7%) died from a cardiovascular cause. Incidence coronary heart disease and stroke were diagnosed in 1,033 (8.5%) and 766 (6.3%) participants, respectively. Functional iron deficiency was associated with a 24% higher risk of coronary heart disease, 26% raised risk of cardiovascular mortality, and 12% increased risk of all-cause mortality compared with no functional iron deficiency. Absolute iron deficiency was associated with a 20% raised risk of coronary heart disease compared with no absolute iron deficiency, but was not linked with mortality. There were no associations between iron status and incident stroke. The researchers calculated the population attributable fraction, which estimates the proportion of events in 10 years that would have been avoided if all individuals had the risk of those without iron deficiency at baseline. The models were adjusted for age, sex, smoking, cholesterol, blood pressure, diabetes, body mass index, and inflammation. Within a 10-year period, 5.4% of all deaths, 11.7% of cardiovascular deaths, and 10.7% of new coronary heart disease diagnoses were attributable to functional iron deficiency. “This analysis suggests that if iron deficiency had been absent at baseline, about 5% of deaths, 12% of cardiovascular deaths, and 11% of new coronary heart disease diagnoses would not have occurred in the following decade,” said Dr. Schrage. “The study showed that iron deficiency was highly prevalent in this middle-aged population, with nearly two-thirds having functional iron deficiency,” said Dr. Schrage. “These individuals were more likely to develop heart disease and were also more likely to die during the next 13 years.” Dr. Schrage noted that future studies should examine these associations in younger and non-European cohorts. He said: “If the relationships are confirmed, the next step would be a randomised trial investigating the effect of treating iron deficiency in the general population.”     Consumption of a bioactive compound from Neem plant could significantly suppress development of prostate cancer National University of Singapore, September 29, 2021   Oral administration of nimbolide, over 12 weeks shows reduction of prostate tumor size by up to 70 per cent and decrease in tumor metastasis by up to 50 per cent   A team of international researchers led by Associate Professor Gautam Sethi from the Department of Pharmacology at the Yong Loo Lin School of Medicine at the National University of Singapore (NUS) has found that nimbolide, a bioactive terpenoid compound derived from Azadirachta indica or more commonly known as the neem plant, could reduce the size of prostate tumor by up to 70 per cent and suppress its spread or metastasis by half.   Prostate cancer is one of the most commonly diagnosed cancers worldwide. However, currently available therapies for metastatic prostate cancer are only marginally effective. Hence, there is a need for more novel treatment alternatives and options.   "Although the diverse anti-cancer effects of nimbolide have been reported in different cancer types, its potential effects on prostate cancer initiation and progression have not been demonstrated in scientific studies. In this research, we have demonstrated that nimbolide can inhibit tumor cell viability -- a cellular process that directly affects the ability of a cell to proliferate, grow, divide, or repair damaged cell components -- and induce programmed cell death in prostate cancer cells," said Assoc Prof Sethi.   Nimbolide: promising effects on prostate cancer   Cell invasion and migration are key steps during tumor metastasis. The NUS-led study revealed that nimbolide can significantly suppress cell invasion and migration of prostate cancer cells, suggesting its ability to reduce tumor metastasis. The researchers observed that upon the 12 weeks of administering nimbolide, the size of prostate cancer tumor was reduced by as much as 70 per cent and its metastasis decreased by about 50 per cent, without exhibiting any significant adverse effects.   "This is possible because a direct target of nimbolide in prostate cancer is glutathione reductase, an enzyme which is responsible for maintaining the antioxidant system that regulates the STAT3 gene in the body. The activation of the STAT3 gene has been reported to contribute to prostate tumor growth and metastasis," explained Assoc Prof Sethi. "We have found that nimbolide can substantially inhibit STAT3 activation and thereby abrogating the growth and metastasis of prostate tumor," he added.   The findings of the study were published in the April 2016 issue of the scientific journal Antioxidants & Redox Signaling. This work was carried out in collaboration with Professor Goh Boon Cher of Cancer Science Institute of Singapore at NUS, Professor Hui Kam Man of National Cancer Centre Singapore and Professor Ahn Kwang Seok of Kyung Hee University.   The neem plant belongs to the mahogany tree family that is originally native to India and the Indian sub-continent. It has been part of traditional Asian medicine for centuries and is typically used in Indian Ayurvedic medicine. Today, neem leaves and bark have been incorporated into many personal care products such as soaps, toothpaste, skincare and even dietary supplements.       Review looks at the efficacy of acupuncture in treating insulin resistance Guangzhou University of Chinese Medicine (China), October 8, 2021 In their report, researcherss from Guangzhou University of Chinese Medicine in China explored the role of acupuncture in treating insulin resistance. The study was published in the journal Complementary Therapies in Clinical Practice. Earlier studies have reported the effectiveness of acupuncture in treating insulin resistance and related conditions. The review looked at acupuncture and its effects on clinical outcomes. The researchers searched the following databases for randomized controlled trials involving insulin resistance patients treated with acupuncture: Cochrane Central Register of Controlled Trials Embase Medline (via OVID) China National Knowledge Infrastructure (CNKI) Wan Fang and China Science and Technology Journal Database (VIP) The studies show that homeostasis model assessment of insulin resistance significantly decreased with acupuncture treatment. Other significant decreases include fasting blood glucose, postprandial blood glucose and fasting insulin. Acupuncture increased insulin sensitivity with very few adverse effects. In sum, acupuncture is a safe and effective alternative treatment for insulin resistance.     Blueberries may improve attention in children following double-blind trial University of Reading (UK), October 10, 2021  Primary school children could show better attention by consuming flavonoid-rich blueberries, following a study conducted by the University of Reading. In a paper published in Food & Function, a group of 7-10 year olds who consumed a drink containing wild blueberries or a matched placebo and were tested on their speed and accuracy in completing an executive task function on a computer. The double blind trial found that the children who consumed the flavonoid-rich blueberry drink had 9% quicker reaction times on the test without any sacrifice of accuracy. In particular, the effect was more noticeable as the tests got harder. Professor Claire Williams, a neuroscience professor at the University of Reading said: "This is the first time that we have seen the positive impact that flavonoids can have on the executive function of children. We designed this double blind trial especially to test how flavonoids would impact on attention in young people as it's an area of cognitive performance that hasn't been measured before. "We used wild blueberries as they are rich in flavonoids, which are compounds found naturally in foods such as fruits and their juices, vegetables and tea. They have been associated with a range of health benefits including antioxidant and anti-inflammatory effects, and our latest findings continue to show that there is a beneficial cognitive effect of consuming fruit and vegetables, tea, coffee and even dark chocolate which all contain flavonoids." The children were then asked to pay attention to an array of arrows shown on a PC screen and press a key corresponding to the direction that the central arrow was facing. The task was repeated over a number of trials, where cognitive demand was manipulated by varying how quickly the arrows appeared, whether there were additional arrows appearing either side of the central arrow, and whether the flanking arrows were pointing in the same/different direction as the central arrow. Previous Reading research has shown that consuming wild blueberries can improve mood in children and young people, simple memory recall in primary school children, and that other flavonoid rich drinks such as orange juice, can also improve memory and concentration. The Wild Blueberry Association of North America provided a freeze-dried powder made from wild blueberries which was used in the study but did not provide any additional financial support and did not play a role in the design of the study. Wild blueberries are grown and harvested in North America, and are smaller than regular blueberries, and are higher in flavonoids compared to regular varieties. The double-blind trial used a flavonoid-rich wild blueberry drink, with a matched placebo contained 8.9g of fructose, 7.99g of glucose and 4 mg of vitamin C matching the levels of nutrients found in the blueberry drink. The amount of fructose is akin to levels found in a standard pear. This was an executive function task- requiring participants to pay attention to stimuli appearing on screen and responding correctly. The task was a simple one- responding to the direction of an arrow in the middle of a screen (by pressing left/right arrow key) but we then varied how quickly the stimuli appeared, whether there was additional arrows appearing either side of the stimuli and whether those flanking arrows were pointing in the same/different direction as they direction you had to respond. There are 6 main classes of flavonoids: Anthocyanins – found in berry fruits such as the blueberries used in this study and also in red wine. Flavonols - found in onions, leeks, and broccoli Flavones - found in parsley and celery, Isoflavones - found in soy and soy products, Flavanones - found in citrus fruit and tomatoes Flavanols—found in green tea, red wine, and chocolate     Nocebo effect: Does a drug's high price tag cause its own side effects? University Medical Center Hamburg (Germany), October 5, 2021  Pricey drugs may make people more vulnerable to perceiving side effects, a new study suggests—and the phenomenon is not just "in their heads." The study delved into the so-called "nocebo effect." It's the negative version of the well-known placebo effect, where people feel better after receiving a therapy because they expected good things. With the nocebo effect, patients' worries over treatment side effects make them feel sick. In this study, researchers found that people were more likely to report painful side effects from a fake drug when told it was expensive. But it wasn't just something people were "making up." Using brain imaging, the researchers traced the phenomenon to specific activity patterns in the brain and spine. "These findings are a strong argument against the perception of placebo and nocebo effects as being only 'fake' effects—created purely by imagination or delusions of the patient," said lead researcher Alexandra Tinnermann. She is with the University Medical Center Hamburg-Eppendorf, in Germany. Dr. Luana Colloca, a researcher at the University of Maryland in Baltimore, agreed. "This is not merely a reflection of people's biases," said Colloca, who wrote an editorial published with the study. "Expectations do modulate symptoms and patients' responses to treatment," she said. For the study, Tinnermann's team recruited 49 healthy volunteers and randomly assigned them to test one of two itch-relieving "medical creams." In reality, both creams were identical and contained no active ingredients. However, people in both groups were told that the products could have the side effect of making the skin more sensitive to pain. There was only one apparent difference between the two phony creams: One came in fancy packing with a high price tag; the other was cheap. After participants applied the creams to their forearms, the researchers had them undergo a standard test that measured their tolerance for heat-induced pain. It turned out that people who'd used the expensive cream were more sensitive to pain during the tests. On average, their pain rating hovered around a 15—within the "mild" pain range—whereas people using the cheap cream barely registered any discomfort. It's likely, Tinnermann said, that people expect a pricey medication to be potent—which could also make them expect more side effects. Colloca agreed. We are all "vulnerable" to such outside influences, she said, be it a drug's price or how it's given (by IV versus mouth, for instance). However, we are not just imagining those placebo or nocebo effects, both researchers noted. Using functional MRI brain scans, Tinnermann's team found specific patterns of nervous system activity in people who had a nocebo response to the pricey cream. That included a change in "communication" between certain brain structures and the spinal cord, Tinnermann said. According to Colloca, research like this can have practical uses. Doctors could, for instance, inform patients that drug prices or other factors can sway their expectations about a treatment's benefits and risks—and that, in turn, can influence whether they feel better or develop side effects. There is, however, no research into whether that kind of knowledge helps prevent patients from the nocebo effect, Tinnermann said. But, she added, health professionals can be aware that patients' expectations "play a huge role in medicine"—and be mindful of how they talk about a medication and its possible side effects. It's an important matter, Colloca said, because the nocebo effect can cause people to stop taking needed medications. Colloca pointed to the example of cholesterol-lowering statins. The potential for those medications to cause muscle pain has been widely reported. And one recent study found evidence that this knowledge can make statin users more likely to report muscle pain side effects. Other research, Colloca said, has shown that when people stop taking their statins, their risk of heart attack and stroke rises.

Gabriel Robertstad Garcia Benito (PhD, NHH Norwegian School of Economics) is Professor at BI Norwegian Business School, Oslo, Norway: www.bi.edu. He has extensive international experience from research, teaching, and academic community service. He has held visiting positions at Copenhagen Business School (Denmark), University of Melbourne (Australia), Henley Business School/University of Reading (UK) and University of Valencia (Spain). Gabriel is Co-Editor of Global Strategy Journal and Consulting Editor of Journal of International Business Studies, and a member of the Editorial Boards of, among others, Academy of Management Perspectives, International Business Review, Journal of World Business, Management and Organization Review, and Management International Review. Gabriel has studied the internationalization dynamics of businesses for three decades, with a focus on the governance, strategy and organization of multinational enterprises, headquarter-subsidiary relationships, and foreign operation mode decisions. His research has appeared in many books and journals, including Global Strategy Journal, Journal of Economic Geography, Journal of International Business Studies, and Journal of Management Studies. His books include Foreign Operation Methods (w/L. Welch and B. Petersen, 2018, 2nd edition), and Multinationals on the Periphery (w/R. Narula, 2007). Gabriel was President of EIBA (European International Business Academy) in 2005, and member of its Board from 1997 to 2007, and has served in various roles in AIB and Strategic Management Society. He organized the 2005 EIBA Conference and was Co-Chair of the 2018 Strategic Management Society Special Conference in Oslo. He was elected Fellow of AIB in 2015, and Fellow of EIBA in 2017. Visit https://www.aib.world/frontline-ib/gabriel-benito/ for the original video interview.

A fermented-food diet increases microbiome diversity and lowers inflammation, study finds Stanford University, July 13, 2021 A diet rich in fermented foods enhances the diversity of gut microbes and decreases molecular signs of inflammation, according to researchers at the Stanford School of Medicine.  In a clinical trial, 36 healthy adults were randomly assigned to a 10-week diet that included either fermented or high-fiber foods. The two diets resulted in different effects on the gut microbiome and the immune system. Eating foods such as yogurt, kefir, fermented cottage cheese, kimchi and other fermented vegetables, vegetable brine drinks, and kombucha tea led to an increase in overall microbial diversity, with stronger effects from larger servings. "This is a stunning finding," said Justin Sonnenburg, PhD, an associate professor of microbiology and immunology. "It provides one of the first examples of how a simple change in diet can reproducibly remodel the microbiota across a cohort of healthy adults." In addition, four types of immune cells showed less activation in the fermented-food group. The levels of 19 inflammatory proteins measured in blood samples also decreased. One of these proteins, interleukin 6, has been linked to conditions such as rheumatoid arthritis, Type 2 diabetes and chronic stress.  "Microbiota-targeted diets can change immune status, providing a promising avenue for decreasing inflammation in healthy adults," said Christopher Gardner, PhD, the Rehnborg Farquhar Professor and director of nutrition studies at the Stanford Prevention Research Center. "This finding was consistent across all participants in the study who were assigned to the higher fermented food group." Microbe diversity stable in fiber-rich diet By contrast, none of these 19 inflammatory proteins decreased in participants assigned to a high-fiber diet rich in legumes, seeds, whole grains, nuts, vegetables and fruits. On average, the diversity of their gut microbes also remained stable. "We expected high fiber to have a more universally beneficial effect and increase microbiota diversity," said Erica Sonnenburg, PhD, a senior research scientist in basic life sciences, microbiology and immunology. "The data suggest that increased fiber intake alone over a short time period is insufficient to increase microbiota diversity."  The study will be published online July 12 in Cell. Justin and Erica Sonnenburg and Christopher Gardner are co-senior authors. The lead authors are Hannah Wastyk, a PhD student in bioengineering, and former postdoctoral scholar Gabriela Fragiadakis, PhD, who is now an assistant professor of medicine at UC-San Francisco. A wide body of evidence has demonstrated that diet shapes the gut microbiome, which can affect the immune system and overall health. According to Gardner, low microbiome diversity has been linked to obesity and diabetes.  "We wanted to conduct a proof-of-concept study that could test whether microbiota-targeted food could be an avenue for combatting the overwhelming rise in chronic inflammatory diseases," Gardner said.  The researchers focused on fiber and fermented foods due to previous reports of their potential health benefits. While high-fiber diets have been associated with lower rates of mortality, the consumption of fermented foods can help with weight maintenance and may decrease the risk of diabetes, cancer and cardiovascular disease. The researchers analyzed blood and stool samples collected during a three-week pre-trial period, the 10 weeks of the diet, and a four-week period after the diet when the participants ate as they chose.  The findings paint a nuanced picture of the influence of diet on gut microbes and immune status. On one hand, those who increased their consumption of fermented foods showed similar effects on their microbiome diversity and inflammatory markers, consistent with prior research showing that short-term changes in diet can rapidly alter the gut microbiome. On the other hand, the limited change in the microbiome within the high-fiber group dovetails with the researchers' previous reports of a general resilience of the human microbiome over short time periods.  Designing a suite of dietary and microbial strategies The results also showed that greater fiber intake led to more carbohydrates in stool samples, pointing to incomplete fiber degradation by gut microbes. These findings are consistent with other research suggesting that the microbiome of people living in the industrialized world is depleted of fiber-degrading microbes.  "It is possible that a longer intervention would have allowed for the microbiota to adequately adapt to the increase in fiber consumption," Erica Sonnenburg said. "Alternatively, the deliberate introduction of fiber-consuming microbes may be required to increase the microbiota's capacity to break down the carbohydrates." In addition to exploring these possibilities, the researchers plan to conduct studies in mice to investigate the molecular mechanisms by which diets alter the microbiome and reduce inflammatory proteins. They also aim to test whether high-fiber and fermented foods synergize to influence the microbiome and immune system of humans. Another goal is to examine whether the consumption of fermented food decreases inflammation or improves other health markers in patients with immunological and metabolic diseases, and in pregnant women and older individuals.  "There are many more ways to target the microbiome with food and supplements, and we hope to continue to investigate how different diets, probiotics and prebiotics impact the microbiome and health in different groups," Justin Sonnenburg said.   Effect of resveratrol intervention on renal pathological injury in type 2 diabetes Capital Medical University (China), July 11, 2021 According to news reporting from Beijing, People's Republic of China, research stated, “Type 2 diabetes (T2D) is a clinically common cardiovascular disease that can lead to kidney damage and adversely affect male fertility and sperm quality. Resveratrol (Res) is a natural product that has a wide range of effects in animals and cell models.” The news correspondents obtained a quote from the research from Capital Medical University, “This research is designed to observe the effect of resveratrol (Res) intervention on renal pathologic injury and spermatogenesis in mice with type 2 diabetes (T2D). Sixty healthy male SD mice without specific pathogens (SPF grade) were selected, and numbered by statistical software to randomize into control group (CG; n=20), model group (MG; n=20) and research group (RG; n=20). Mice in CG were given regular diet, while those in MG and RG were fed with high fat diet. Subsequently, RG was given Res intervention while MG received no treatment. Biochemical indexes [triglyceride (TG), total cholesterol (TC), fasting blood glucose (FBG), 24-hour urinary albumin excretion rate (24h-UAER)] of mice in the three groups before and after intervention were observed and recorded. The effect of Res on oxidative stress, kidney histopathological structure, spermatogenic function, sperm density and viability of mice, as well as spermatogenic cell cycle of testis were determined. Res reduced hyperlipidemia and hyperglycemia in T2D mice. By reducing malondialdehyde (MDA) and increasing superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px), Res relieved oxidative stress and alleviated kidney tissue damage. In addition, Res improved the spermatogenic function of T2D mice by increasing the sperm density and survival rate and restoring the percentage of spermatogenic cells at all levels.” According to the news reporters, the research concluded: “Res intervention in T2D mice can reduce kidney tissue damage, lower blood glucose (BG), and improve spermatogenic function by increasing sperm density and restoring the percentage of spermatogenic cells at all levels.” This research has been peer-reviewed.     Eating whole grains linked to smaller increases in waist size, blood pressure, blood sugar Study in middle- to older-aged adults suggests whole grains may protect against heart disease Tufts University, July 13, 2021 Middle- to older-aged adults who ate at least three servings of whole grains daily had smaller increases in waist size, blood pressure, and blood sugar levels over time compared to those who ate less than one-half serving per day, according to new research. Published July 13, 2021, in the Journal of Nutrition, the study by researchers at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University examined how whole- and refined-grain intake over time impacted five risk factors of heart disease: Waist size, blood pressure, blood sugar, triglyceride, and HDL ("good") cholesterol. Using data from the Framingham Heart Study Offspring Cohort, which began in the 1970s to assess long-term risk factors of heart disease, the new research examined health outcomes associated with whole- and refined-grain consumption over a median of 18 years. The 3,100 participants from the cohort were mostly white and, on average, in their mid-50s at the start of data collection. The research team compared changes in the five risk factors, over four-year intervals, across four categories of reported whole grain intake, ranging from less than a half serving per day to three or more servings per day. According to the Dietary Guidelines for Americans 2020-2025, the recommended amount of whole grains is three or more servings daily. An example of a serving is one slice of whole-grain bread, a half cup of rolled oats cereal, or a half cup of brown rice. The results showed that for each four-year interval:   Waist size increased by an average of over 1 inch in the low intake participants, versus about ½ inch in the high intake participants. Even after accounting for changes in waist size, average increases in blood sugar levels and systolic blood pressure were greater in low intake participants compared to high intake participants. The researchers also studied the five risk factors across four categories of refined-grain intake, ranging from less than two servings per day to more than four servings per day. Lower refined-grain intake led to a lower average increase in waist size and a greater mean decline in triglyceride levels for each four-year period. "Our findings suggest that eating whole-grain foods as part of a healthy diet delivers health benefits beyond just helping us lose or maintain weight as we age. In fact, these data suggest that people who eat more whole grains are better able to maintain their blood sugar and blood pressure over time. Managing these risk factors as we age may help to protect against heart disease," said Nicola McKeown, senior and corresponding author and a scientist on the Nutritional Epidemiology Team at the USDA HNRCA. "There are several reasons that whole grains may work to help people maintain waist size and reduce increases in the other risk factors. The presence of dietary fiber in whole grains can have a satiating effect, and the magnesium, potassium, and antioxidants may contribute to lowering blood pressure. Soluble fiber in particular may have a beneficial effect on post-meal blood sugar spikes," said Caleigh Sawicki. Sawicki did this work as part of her doctoral dissertation while a student at the Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy at Tufts University and while working with the Nutritional Epidemiology Team at the USDA HNRCA. The greatest contributor to whole-grain intake among participants was whole-wheat breads and ready-to-eat whole-grain breakfast cereals. The refined grains came mostly from pasta and white bread. The difference in health benefits between whole and refined grains may stem from the fact that whole grains are less processed than refined grains. Whole grains have a fiber-rich outer layer and an inner germ layer packed with B vitamins, antioxidants, and small amounts of healthy fats. Milling whole grains removes these nutrient-dense components, leaving only the starch-packed refined grain behind. "The average American consumes about five servings of refined grains daily, much more than is recommended, so it's important to think about ways to replace refined grains with whole grains throughout your day. For example, you might consider a bowl of whole-grain cereal instead of a white flour bagel for breakfast and replacing refined-grain snacks, entrees, and side dishes with whole-grain options. Small incremental changes in your diet to increase whole-grain intake will make a difference over time," McKeown said. Methodology To measure daily grain intake, the researchers used diet questionnaires that participants completed every four years from 1991 to 2014, resulting in a median of 18 years of data. Dietary assessment data came from five study examinations, and observations were only included if participants attended at least two consecutive examinations with accurate dietary data. Participants with diabetes at baseline were excluded. The statistical analysis was adjusted for factors that might influence the results, including other aspects of a healthy diet. Limitations of the study include the fact that food consumption is self-reported, and participants may over- or under-estimate intake of certain foods based on perceived social desirability. Due to its observational design, the study does not reflect a causal relationship.   Antibiotics in early life could affect brain development Exposure to antibiotics in utero or after birth could lead to brain disorders in later childhood Rutgers University, July 14, 2021 Antibiotic exposure early in life could alter human brain development in areas responsible for cognitive and emotional functions, according to a Rutgers researcher. The laboratory study, published in the journal iScience, suggests that penicillin changes the microbiome - the trillions of beneficial microorganisms that live in and on our bodies - as well as gene expression, which allows cells to respond to its changing environment, in key areas of the developing brain. The findings suggest reducing widespread antibiotic use or using alternatives when possible to prevent neurodevelopment problems.  Penicillin and related medicines (like ampicillin and amoxicillin) are the most widely used antibiotics in children worldwide. In the United States, the average child receives nearly three courses of antibiotics before the age of 2. Similar or greater exposure rates occur in many other countries.  "Our previous work has shown that exposing young animals to antibiotics changes their metabolism and immunity. The third important development in early life involves the brain. This study is preliminary but shows a correlation between altering the microbiome and changes in the brain that should be further explored," said lead author Martin Blaser, director of the Center for Advanced Biotechnology and Medicine at Rutgers. The study compared mice that were exposed to low-dose penicillin in utero or immediately after birth to those that were not exposed. They found that mice given penicillin experienced substantial changes in their intestinal microbiota and had altered gene expression in the frontal cortex and amygdala, two key areas in the brain responsible for the development of memory as well as fear and stress responses.  A growing body of evidence links phenomena in the intestinal tract with signaling to the brain, a field of study known as the "gut-brain-axis." If this pathway is disturbed, it can lead to permanent altering of the brain's structure and function and possibly lead to neuropsychiatric or neurodegenerative disorders in later childhood or adulthood. "Early life is a critical period for neurodevelopment," Blaser said. "In recent decades, there has been a rise in the incidence of childhood neurodevelopmental disorders, including autism spectrum disorder, attention deficit/hyperactivity disorder and learning disabilities. Although increased awareness and diagnosis are likely contributing factors, disruptions in cerebral gene expression early in development also could be responsible." Future studies are needed to determine whether antibiotics directly effect brain development or if molecules from the microbiome that travel to the brain disturb gene activity and cause cognitive deficits.  The study was conducted along with Zhan Gao at Rutgers and Blaser's former graduate student Anjelique Schulfer, as well as Angelina Volkova, Kelly Ruggles, and Stephen Ginsberg at New York University, who all played important roles in this joint Rutgers-New York University project.   Taking the brain out for a walk A recent study shows that spending time outdoors has a positive effect on our brains Max Planck Institute for Human Development, July 15, 2021 If you're regularly out in the fresh air, you're doing something good for both your brain and your well-being. This is the conclusion reached by researchers at the Max Planck Institute for Human Development and the Medical Center Hamburg-Eppendorf (UKE). The longitudinal study recently appeared in The World Journal of Biological Psychiatry. During the Corona pandemic, walks became a popular and regular pastime. A neuroscientific study suggests that this habit has a good effect not only on our general well-being but also on our brain structure. It shows that the human brain benefits from even short stays outdoors. Until now, it was assumed that environments affect us only over longer periods of time. The researchers regularly examined six healthy, middle-aged city dwellers for six months. In total, more than 280 scans were taken of their brains using magnetic resonance imaging (MRI). The focus of the study was on self-reported behavior during the last 24 hours and in particular on the hours that participants spent outdoors prior to imaging. In addition, they were asked about their fluid intake, consumption of caffeinated beverages, the amount of time spent outside, and physical activity, in order to see if these factors altered the association between time spent outside and the brain. In order to be able to include seasonal differences, the duration of sunshine in the study period was also taken into account. Brain scans show that the time spent outdoors by the participants was positively related to gray matter in the right dorsolateral-prefrontal cortex, which is the superior (dorsal) and lateral part of the frontal lobe in the cerebral cortex. This part of the cortex is involved in the planning and regulation of actions as well as what is referred to as cognitive control. In addition, many psychiatric disorders are known to be associated with a reduction in gray matter in the prefrontal area of the brain. The results persisted even when the other factors that could also explain the relationship between time spent outdoors and brain structure were kept constant. The researchers performed statistical calculations in order to examine the influence of sunshine duration, number of hours of free time, physical activity, and fluid intake on the results. The calculations revealed that time spent outdoors had a positive effect on the brain regardless of the other influencing factors. "Our results show that our brain structure and mood improve when we spend time outdoors. This most likely also affects concentration, working memory, and the psyche as a whole. We are investigating this in an ongoing study. The subjects are asked to also solve cognitively challenging tasks and wear numerous sensors that measure the amount of light they are exposed to during the day, among other environmental indicators," says Simone Kühn, head of the Lise Meitner Group for Environmental Neuroscience at the Max Planck Institute for Human Development and lead author of the study. The results therefore, support the previously assumed positive effects of walking on health and extend them by the concrete positive effects on the brain. Because most psychiatric disorders are associated with deficits in the prefrontal cortex, this is of particular importance to the field of psychiatry. "These findings provide neuroscientific support for the treatment of mental disorders. Doctors could prescribe a walk in the fresh air as part of the therapy - similar to what is customary for health cures," says Anna Mascherek, post-doctoral fellow in the Department of Psychiatry and Psychotherapy of the Medical Center Hamburg-Eppendorf (UKE) and co-author of the study. In the ongoing studies, the researchers also want to directly compare the effects of green environments vs urban spaces on the brain. In order to understand where exactly the study participants spend their time outdoors, the researchers plan to use GPS (Global Positioning System) data and include other factors that may play a role such as traffic noise and air pollution.     Vitamin C found to block growth of cancer stem cells, says peer reviewed study University of Salford (UK),  July 8, 2021   Increasingly, researchers are discovering the role played by cancer stem cells in the growth and spread of the disease. In groundbreaking new research, vitamin C showed its ability to target cancer stem cells and stop their growth – preventing the recurrence of tumors. Although mainstream medicine has been slow to accept the cancer-fighting properties of vitamin C, the exciting results of this study could help to change that. It's official: Vitamin C interferes with cancer stem cell metabolism In a newly-published study conducted at the University of Salford in Manchester, vitamin C demonstrated its power to stop tumors in their tracks by interfering with cancer stem cell metabolism – suppressing their ability to process energy for survival and growth. Cancer stem cells are responsible for triggering tumor recurrence, and promoting their growth and metastasis. Researchers believe that cancer stem cells give cancer its ability to resist chemotherapy and radiation – the reason for treatment failure in advanced cancer patients. The study, helmed by researchers Michael P. Lisanti and Gloria Bonucelli, was published last month in Oncotarget, a peer-reviewed journal. Peer-reviewed studies are considered the gold standard of scientific research. The study was the first to explore the effects of vitamin C on cancer stem cells – and provided the first evidence that vitamin C, in the form of ascorbic acid, can target and kill them. In a side-by-side comparison of seven different substances, vitamin C even outperformed an experimental cancer drug. Vitamin C works ten times better than the experimental cancer drug 2-DG The team investigated the impact on cancer stem cells of seven different substances. Three were natural substances, three were experimental drugs, and one was an FDA-approved clinical drug that is widely used. The natural products studied, along with vitamin C, were silibinin – derived from milk thistle seeds – and caffeic acid phenyl ester – or CAPE – derived from honeybee propolis. The experimental drugs were actinonin, FK866 and 2-DG, and the clinical drug was stiripentol. Researchers noted that vitamin C destroyed cancer stem cells by inducing oxidative stress. And, the vitamin performed this process ten times more effectively than 2-DG. Vitamin C used two different mechanisms of action to attack cancer stem cells. It worked as a pro-oxidant in cancer cells, depleting them of the antioxidant glutathione and causing oxidative stress and apoptosis – or cell death. It also inhibited glycolysis, which is the process that creates energy production in cell mitochondria. By inhibiting glycolysis, vitamin C inhibited mitrochondrial protein synthesis in cancer stem cells – while leaving healthy cells unaffected. Non-toxic vitamin C lacks the serious side effects of many pharmaceutical drugs Both experimental and approved cancer drugs can feature serious adverse effects, including thrombocytopenia – a deficiency of platelets in the blood that can cause bruising and slow blood clotting. They can also induce lymphopenia – a decrease in the body's infection-fighting white blood cells – and anemia, or low red blood cells. And the clinically-approved drug used in the study, stiripentol, can cause severe nausea, vomiting and fatigue. On the other hand, the National Cancer Center reports that high-dose vitamin C has caused very few side effects when used in clinical studies. Scientifically speaking, the future looks bright for vitamin C All seven of the substances tested inhibited the growth of cancer cells to varying degrees – including the non-toxic natural substances. But researchers said the most “exciting” results were with vitamin C. The research team concluded that vitamin C was a “promising new agent,” and called for more study to explore its use as an adjunct to conventional cancer therapies to prevent tumor recurrence and growth. “Vitamin C is cheap, natural, non-toxic and readily available, so to have it as a potential weapon in the fight against cancer would be a significant step,” observed Dr. Lisanti. As in most of the successful studies showing vitamin C's cancer-fighting properties, researchers used high doses of vitamin C, administered intravenously. IV vitamin C therapy is available in some alternative and holistic cancer treatment clinics worldwide. The real reason why vitamin C is ignored by conventional medicine and the mainstream media Again, vitamin C was 1,000 percent more effective than 2-DG, an experimental pharmaceutical drug – in targeting cancer stem cells. If vitamin C were developed by big pharma, these results would be shouted from the rooftops and featured in newspaper headlines. Yet, as always, “the powers that be” in mainstream medicine respond with…crickets. The reason; say natural health experts, is all too obvious. As a natural nutrient and vitamin, vitamin C can't be patented, and is inexpensive and easy to obtain. Therefore, there is no incentive for cancer clinics to promote it – when they can instead rake in the profits from chemotherapy. The indifference of conventional medicine to vitamin C is all the more frustrating because the nutrient has been shown to be an effective and non-toxic anti-cancer agent in previous studies, including many conducted by Nobel prize-winning scientist Linus Pauling. Vitamin C has been shown in a Japanese study to cut mortality in cancer patients by 25 percent. In addition, it has inhibited tumors in animal studies, and been shown to kill cancer cells in a wide variety of cancer cell lines. How much longer will the potential of this safe and powerful cancer-fighting nutrient be overlooked?     Mothers' high-fat diet affects clotting response in sons, mice study finds University of Reading (UK), July 13, 2021 Mothers who follow a high fat diet may be affecting the cardiovascular health of their sons, according to a new study in mice. In a paper published in Scientific Reports, a team of scientists found that the male children of mice mothers who were fed on a high fat diet during pregnancy had unhealthy platelets, which are responsible for clotting, when fed on a high fat diet themselves. Although both male and female children of the mothers fed on a high fat diet showed a variety of risks associated with cardiovascular disease, it was only the platelets of male mice which were considered hyperactive. These platelets were larger, more volatile and showed signs of stress compared to offspring fed on a normal diet. Dr. Dyan Sellayah, lecturer in cellular and organismal metabolism at the University of Reading said: "Heart disease is one of the UK's biggest killers and mounting evidence suggests that the risk of developing it may be increased during early development, particularly during the gestation period where mothers have a high-fat diet/are obese. The underlying mechanisms by which an unhealthy maternal diet may impact heart disease risk remains largely unknown. "This study used a mouse model of maternal obesity to understand how specialist blood cells known as platelets may be programmed during pregnancy. Platelets are important for blood clotting but are also the cause of heart attacks and strokes if they are activated at the wrong time and place." Children of the mothers fed on a high fat diet who followed a control diet however did not show the same concerning heart disease risks. The offspring from the group given a control diet had very similar levels of fat mass, cholesterol and other markets of cardiovascular health as the children of mothers fed a standard diet. In addition, where mothers had been fed a standard diet and their offspring fed a high fat diet, those children had higher levels of fat mass and other cardiovascular markers, but their platelets were statistically similar to the other groups apart from where both mum and child were fed high fat diet.  Dr. Craig Hughes, lecturer in cardiovascular biology at the University of Reading said: "This study revealed that maternal obesity during pregnancy causes offspring platelets to become hyperactive in response to a high-fat diet in adulthood. These results raise the possibility that the risk of unwanted blood clotting (aka thrombosis) in adulthood could be altered during pregnancy by diet of the mother. "The specific mechanisms for why high fat diets affect male offspring are still being investigated but we can see that there's likely to be a double-hit where both mums and sons diets together were required to see these bigger, more hyperactive platelets."

TALAM City est le 6ème album de Julien Jacob (AZN/ Inouïe Dist.) Bienvenue dans la ville imaginaire de l'artiste ! Douze plages composent son nouvel opus. Douze places de sa ville mystérieuse dont Julien nous propose la découverte sensorielle. "En chacun de nous se trouve un lieu secret", nous dit-il. "Un lieu où reposent notre passé, nos émotions, nos doutes, nos certitudes, nos joies, nos peines, nos forces et nos faiblesses, notre devenir, notre existence… Nous visitons souvent ce lieu magique afin d'y trouver le repos, la paix, les réponses à nos questions, l'énergie, l'inspiration… chacun de nous possède en lui sa ville imaginaire. La mienne se nomme TALAM City !" Dans son nouvel album, Julien Jacob nous conte sa ville dans sa langue imaginaire. Cette langue qu'il a lui-même créée et qu'il nous chante depuis toujours à travers ses albums. C'est un langage non codé qui s'adresse au cœur plutôt qu'à l'intellect. Chacun, selon sa sensibilité, fait son propre voyage. Comme à son habitude l'artiste, dans cette nouvelle œuvre, signe la production artistique, joue tous les instruments et nous offre ses multiples voix. Oscillant entre graves et aigus, tour à tour caressante, incantatoire, joyeuse, mélancolique, ferme ou rassurante, sa voix unique et envoûtante nous chante sa ville intérieure. Tantôt cool, rock, roots, l'univers artistique de Julien Jacob ne connaît pas de frontières !   Julien Jacob, la biographie L'histoire de Julien Jacob commence par sa naissance au Dahomey (Bénin). Sa famille quitte l'Afrique quelques temps plus tard, et s'installe avec lui dans le sud de la France. C'est loin de sa terre natale que se poursuit sa route… Sur le vieil électrophone de son père, craquent souvent des vinyles de jazz, de musiques noires américaines et afro-cubaines. Le jeune Julien se prend très tôt de passion pour la musique. À 17 ans, il est chanteur dans un groupe de rock et découvre la scène. Ensemble, ils iront même jouer au Golf Drouot, à Paris, mythique salle de concerts de l'époque. Quelques années après, il quitte le groupe et se consacre à la composition de sa propre musique. Cette étape le verra cheminer vers son identité artistique et sera enrichie de rencontres marquantes, comme celle de David Bowie, en tournée en France… ou cette nuit entière passée en compagnie de Fela et de ses musiciens... À cette époque, Julien écrit ses textes en français, langue qu'il affectionne et dans laquelle il écrira, plus tard, ses livres. 1995, il s'installe en Bretagne, et publie son premier livre ‘ALORS, SOIS'. Un ouvrage poétique et très personnel qui traduit sa vision spirituelle de la vie. Dans la continuité, il enregistre un 4-titres auto-produit. C'est à partir de cet enregistrement qu'il révèle au public ce qui sera désormais sa particularité : sa langue imaginaire ! Langue non codée qu'il a lui-même créée. Ses mots, véhiculés par ses multiples voix, ont pour chemin de s'adresser aux coeurs où qu'ils soient sur la planète. Puis, il sort son premier album et, dès lors, part sur les routes. Pour son quatrième album et ceux qui suivront, il décide de prendre en main la direction artistique de sa musique. Dorénavant, il arrangera chacune de ses oeuvres et jouera lui-même tous les instruments ! Son goût pour l'image, l'amène aussi à composer les bandes originales de films documentaires. La musique de Julien Jacob ne connaît pas de frontières. À chaque sortie de ses productions, il va rencontrer le public aux quatre coins du monde. Il arpente les scènes du WOMAD festival à Singapour, Australie, Nouvelle-Zélande, Seattle, Reading (UK), Palerme (Sicile), Caceres (Espagne), Las Palmas (Canaries). À la sortie d'un concert Womad à Seattle, Peter Gabriel vient le remercier pour sa prestation. Les Francofolies de Montréal et le Paléo festival de Nyon l'accueillent. Il participe au London Jazz festival. Il fait des premières parties prestigieuses (Suzanne Vega, Cesaria Evora...) Il sillonne également la France et l'Europe à travers de nombreuses salles. Le chanteur Bobby McFerrin l'invite sur scène pour deux concerts en improvisations vocales dans son BOBBLE opéra au sein du STIMMEN Festival en Suisse… "Je n'ai pour unique passeport que ma musique. Il est la promesse de multitudes de regards échangés et d'émotions partagées par-delà les frontières. Puisse-t-il n'arriver à expiration qu'après mon dernier souffle !" Sa marche infatigable passera certainement près de chez vous... Titres interprétés lors de la #SessionLive Amouss Live RFI Talam City extrait de l'album Talam City Eve Live RFI   Musiciens Julien Jacob, chant Hakim Hamadouche, mandole-luth Son Fabien Mugneret et Benoît Letirant.   Playlist de Julien Jacob Rachid Taha Je suis africain, voir le clip  Otis Redding Dock of the Bay The Rolling Stones Under my thumb (album Aftermath 1966) et Brian Jones au marimba Fela Kuti ITT 

Have you ever felt a burning desire to know what might have been, had you chosen a different course of action? That's "counterfactual curiosity" -- the desire to know about possible alternative outcomes -- and it can sometimes cause us pain and regret. So why have it? Dr. Lily FitzGibbon, postdoctoral research fellow at the School of Psychology and Clinical Language Sciences at the University of Reading (UK), helps me understand better. Our theme and other music are by Sean Balick.

Emilio Rodríguez-Álvarez is an archaeologist specialising in the archaeology of ancient Greece, the study of pottery technology, geographic Information Systems and maritime archaeology. He finished his B.A. at the University of Santiago de Compostela (Galicia) and took his M.A. from University of Reading (UK); after working in Galicia he moved to the University of Arizona (US), in order to work on his Ph.D.Emilio is a keen freediver himself and is especially interested in the ancient divers of the Mediterranean, he's done work on, for example, sponge harvesting in the archaeological record of the Mediterranean Basin.and also has a general fascination with all the indigenous, traditional freediving cultures still extant around the world and what we can learn from them.In this episode we discuss:Emilio is from Galicia!How is the discipline of ancient archeology done and how is the science coming along?Sponges as shock absorbers in helmets!A collection of references to freediving in antiquity.The difficulty of doing research and problems with exploring the evidence of ancient freediving.How did humans start with freediving?The search for surfers ear.Neanderthals freediving in ancient Iraq?Extant traditional freediving cultures around the world such as the Ama, Bajau, Moken etc.The genetics of the Bajau Laut people and their enlarged spleens.Ancient Polynesian diving for pearls.Pearl diving in antiquity and in the Sumerian epic of GilgameshHow deep have we been diving through history.Aristotle and his ear perforation claims!Ancient nose clips made from pearl shells.Did Greek divers really deliberately blow out their ear drums?Early depletion of sea life and how it affected freediving.Ancient freediving masks and snorkels.The problem with bronze knifes in the 6th century BCE.Diving for sponges in the Mediterranean and how it was done.What were they doing with a mouthful of olive oil?! Ancient flashlight?!The story of Yorgos Haggi Statti.Dances that imitate divers health issues.The role of female freedivers in ancient Greece.DESERT ISLAND QUESTIONS

Sarianna Lundan holds the Chair in International Management and Governance at the University of Bremen in Germany. She received her PhD from Rutgers University (US), and has held prior appointments at the University of Reading (UK) and at Maastricht University (The Netherlands). She is a Finnish citizen, and has also been an Associate Research Fellow at the Research Institute of the Finnish Economy (ETLA), a think-tank focused on economic policy. She is currently a Distinguished Visiting Professor at Aalto University in Finland. She has published widely in journals and books, and has co-authored with John H. Dunning the second edition of Multinational Enterprises and the Global Economy, which continues to be an influential reference work in the field of international business. She is the inaugural Editor-in-Chief of the Journal of International Business Policy (JIBP) and member of seven other editorial boards. She has participated extensively in the work of UNCTAD in connection with the World Investment Reports and the Investment Policy Reviews, and served briefly as a Senior Economic Officer there. She has also worked on diverse policy-related projects for the World Bank, OECD and European Commission. She is a Fellow of the European International Business Academy (EIBA) and the Academy of International Business (AIB). Visit https://www.aib.world/frontline-ib/sarianna-lundan/ for the original video interview.

Our guest is the proud founder of The Mixed Identity. She resides over in the UK and gives us an introduction to what it was for her as a mixed-race/multiracial being growing up in England. She often expresses herself, her identity, and her love for the culture via her blog. Check her out! www.mixed-identity.co.uk IG: @the.mixed.identity

Rob Sutcliff - An expert UI & UX designer from Reading UK explains there is no such thing as rational decision making. He brings in examples from various aspects of human psychology and further provides examples on how we make decisions based on our decisions and once the decisions are made we try to provide a rational explanation to the same. Podcast Reference Course: https://www.udemy.com/course/master-digital-product-design-ux-research-ui-design/?couponCode=THINKING-PSYCH

The story of Khairi Saadallah, the Libyan knife attacker in a British park, provides reasons to believe that his motive could have been terrorism, simple criminal murder, a psychotic episode or homophobia. Hear why, what red flags were missed and how these motives are not mutually exclusive.

The story of Khairi Saadallah, the 25-year-old Libyan knife attacker in a British park, provides reasons to believe that his motive could have been terrorism, simple criminal murder, a psychotic episode or homophobia. Hear why, what red flags were missed, and how these motives are not mutually exclusive. Khairi was referred to UK counterterrorism organizations, but was not on a watch list. He has a history of incarceration for various crimes, and had just been released days before the attack. He also had a history of psychiatric hospitalizations for various diagnoses and had been seen by mental health professionals hours before his attack. His friends told of his homophobia, a significant piece of the puzzle because the men he killed and wounded were gay. After you hear all the gruesome details, you'll ask yourself: could this attack have been prevented or are there too many terrorists, criminals and mentally ill to watch them all?

Unframed — In this episode, I chat with Carly Whitaker about her artistic, curatorial and research practice. This is the 6th episode in a series on Unframed called "Artists in Isolation” which profiles South African artists during the lockdown period of the COVID-19 pandemic. We are living through unprecedented times, where we are needing to find new ways of connecting with each other and the broader art industry, of being inspired, and of creating more platforms for artists. Carly Whitaker is an artist, curator, researcher and lecturer based in Johannesburg, South Africa. She holds a BA Fine Arts and a MA in Digital Interactive. She has participated in numerous exhibitions at art spaces in Johannesburg, Freiburg, Casablanca, Miami and Sao Paulo. Her curatorial projects include Floating Reverie, an online digital residency programme, which has been running for over five years and Blue Ocean an online digital project space. She is interested in the positioning of this as artistic research and investigating how artists can develop a practice online. Through her own practice she engages in a constant exploration of how we communicate through media and the ways we use technology to create dialogues, form connections between ourselves and the digital space. Carly is currently extending her practice and research into new areas with her PhD at the University of Reading (UK) with a focus on curating and networked methodologies in South Africa. Enjoy listening to my conversation with Carly Whitaker.

In this episode, I chat with Carly Whitaker about her artistic, curatorial and research practice. This is the 6th episode in a series on Unframed called "Artists in Isolation” which profiles South African artists during the lockdown period of the COVID-19 pandemic. We are living through unprecedented times, where we are needing to find new ways of connecting with each other and the broader art industry, of being inspired, and of creating more platforms for artists. Carly Whitaker is an artist, curator, researcher and lecturer based in Johannesburg, South Africa. She holds a BA Fine Arts and a MA in Digital Interactive. She has participated in numerous exhibitions at art spaces in Johannesburg, Freiburg, Casablanca, Miami and Sao Paulo. Her curatorial projects include Floating Reverie, an online digital residency programme, which has been running for over five years and Blue Ocean an online digital project space. She is interested in the positioning of this as artistic research and investigating how artists can develop a practice online. Through her own practice she engages in a constant exploration of how we communicate through media and the ways we use technology to create dialogues, form connections between ourselves and the digital space. Carly is currently extending her practice and research into new areas with her PhD at the University of Reading (UK) with a focus on curating and networked methodologies in South Africa. Enjoy listening to my conversation with Carly Whitaker.

Kitchen Sink # 99 Playlist Meadowlake – I Won't Let You Down (single, Nov 19, Netherlands based dream pop) Pendant – Through a Coil (Through a Coil, Oakland-based musician Christopher Adams). Superdrone – Freedom (Creation EP, Southampton UK psych gaze) Theatre Royal – Down South With the Chameleons (B-Sides & Other Cuts, Rochester UK indie pop) Break 1 SPC ECO – All in Time (February EP, Dean Garcia and Rose Berlin, UK electronica) Cerulean Veins – Fell in Love (Blue, San Diego coldwave) Black Swan Lane – Condannare (Vita Eterna, Atlanta dream pop, Jack Sobel and John Kolbeck) Schonwald – Inner Sin (new single, Italian post punk) Alienbaby Collective – Degenerate Moon (Fishbowl / Terrestrial double EP, Liú Mottes, Netherlands noise pop) Pure Hex – Fall (Pure Hex EP, SF based dream pop) Honeymoan – Still Here (Weirdo EP, Cape Town bedroom pop) Chromatics – Touch Red (Closer to Grey, Portland OR synth pop) Lake Ruth and Listening Center – How I Hear You (The Sunday Experience EP, released as a benefit for music writer Mark Barton) Stephen Fellows – Not Going Down (Slow Glass, Sheffield UK post punk from ex-Comsat Angels vocalist) Break 2 Smashing Orange – Something You Said (from Collide / Something You Said dual release with The Sunflowers, Clawfist Singles Club, Wilmington, Delaware shoegaze) Peel Dream Magazine – Pill (Agitpop Alterna, forthcoming, NY based indie rock) Grrrl Gang – Love Song (Here to Stay!, Indonesian pop punk) Jeanines – Been in the Dark (Things Change EP, out March, Brooklyn indie pop) Postcards – Spiderwebs (The Good Soldier, Beirut Lebanon dream pop) The Fast Camels – Blissful Serenity (Full of Strange, Glasgow psych pop) Eyelids – At Sea (The Accidental Falls, Portland OR indie pop, band members’ second-to-none pedigrees earned from time spent in Guided By Voices, The Decemberists, Stephen Malkmus and Elliott Smith. Featuring lyrics written by poet and frequent Tim Buckley collaborator Larry Beckett that span over four decades and produced by REM iconoclast Peter Buck). Records – Held Up High (Shades in Bed, 1979 UK power pop with Will Birch and John Wicks RIP) Nada Surf – So Much Love (Never Not Together, Feb 7th, NY indie rock) Go Betweens – You Tell Me (Australian indie pop, Tallulah, 1987) Dropkick – Feeling Never Goes Away (The Scenic Route, Andrew Taylor, Scottish jangle pop) Lost Ships – All of the Pieces (title track from EP, Portsmouth UK jangle pop) Gaarden – The Fall (from The Fall, Sydney dream pop) Mundy's Bay – Goodbye (Lonesome Valley out March, Montreal dream pop) The Proper Ornaments – Black Tar (Mission Bells out 2/28, James Hoare and Max Oscarnold, London UK indie pop) Break 3 Chapterhouse – Something More (Ambient Version), C90 box set, Reading UK dream pop, song in original version from 1991’s Whirlpool) Flyingpool – Orange Sky (Flyingpool Demo, Belgian dream pop) Pale Saints – True Coming Dream (Woodhouse Studio Demo), 30th anniversary of The Comforts of Madness Indoor Voices – Heart (Animal, new, not announced, missed by accident) Seasurfer – Lovers Breakdown (single, German dreamgaze) Dead Horse One – Lost (The West is the Best, French shoegaze) Galaxina – Iris (new single, Andalusia Spain shoegaze) Magic Shoppe – Doppelgänger (A side to exclusive vinyl release of Doppelgänger / S.F.O., Boston psych) Flyying Colours – Goodtimes (new, Melbourne psych gaze) Radio Supernova – Kyyti (Tähtiin, Finnish shoegaze) Purple Heart Parade – Starwheel (Desolation Angel EP, new, UK psych reminds of The Verve) Break 4 Pastel Coast – La Nuit (Hovercraft, French jangle pop) Deserta – Save Me (Black Aura My Sun, LA dream pop) Iress – Shamed (new single, LA shoegaze)

Today we discuss the upcoming 8-week Action for Happiness course which we are facilitating in Reading/UK from 10th September 2019.  We provide an overview of what to expect from this 'Exploring What Matters' course which deals with the big questions around happiness and how we can lead happier lives.  You can book your place via this link: https://www.eventbrite.co.uk/e/the-action-for-happiness-course-reading-10-sep-2019-tickets-61685270304?utm-medium=discovery&utm-campaign=social&utm-content=attendeeshare&aff=escb&utm-source=cp&utm-term=eventcard

We learn about some of the surprising differences between Canada and the UK, about finding Expat groups for advice, and a bit about Brexit.

#TimRoberts is one of my role models. He is a deeply valued friend and an inspiration to me and many in our network. He was recognised in March 2019 by all of the #SandlerFranchise owners when he was voted the #DavidHSandlerAward winner for his contribution to our community. Tim and I discuss selling with honour. What is sacred to Tim? Trust, honour, integrity are his guiding principles. He explores the guiding principles that have helped him become a giant in his market and in the #SandlerNetwork. We explore the meaning and realities of #service and #contribution. These are not tree hugger speak for rolling over and being the whipping boy for your customers or being run ragged in servitude. They take courage and vulnerability. They require you to have a "no hostage" policy & culture, no judgement, a growth mindset. Tim's core values are based in trust & justice. He is the keeper of the Sandler brand. His approach to selling is refreshingly judgement free. What makes him stand apart from this competitors and his peers is his willingness to lose his self, subordinating his ego to the service of others. Time explains how to build trust, encourage transparency and discover the truth. Tim's wife Katie contracted with Tim, "No plan B" when he first bought their franchise. He explains what it means to be vulnerable, accountable and authentic, raising the bar - say what you do and do what say. Tim explains why a problem/hurt is a gift. Reframing problems as a temporary challenge means you can overcome them, but continuing to perceive it as a problem makes them a burden.  This interview is a keeper and one you will want to listen to several times. Please share this interview with the people who lead your business, with your clients, with your suppliers and with your partners. I welcome your comments. If you want to learn how to meet your potential, please get in touch with me via email: mcauchi(at)sandler(dot)com Or via LinkedIn: https://www.linkedin.com/in/sandlerchannelsalesexpert/ Or call me on +44 7515 937 two two 1 If you want to come to a Sandler class near Reading UK, put "crash a class" in the subject line of your email and make sure you let me have your phone number so we can discuss what you want to learn from attending the session

Which unusual mean of transportation Alex use from time to time? Why monitoring of data quality does matter and what is the very efficient contrary of SCD in SSIS in BI loading process? Which skill is important if you want to jump into the IT market?Find out the answers on these questions and much, much more.Alex Whittles is the owner and principle consultant at Purple Frog, a SQL Server Business Intelligence consultancy in the UK with multinational clients in a variety of sectors. He specialises in all aspects of dimensional data modelling, data warehousing, ETL and cubes using the SQL Server stack.Alex has an MSc (Master of Science) in Business Intelligence, is a chartered engineer, and a member of Mensa. Community leadership includes being on the SQLBits committee, Director of SQL Relay, founder and leader of the Birmingham Data Platform user group.Alex is also a regular speaker at many SQL Server events around the world including SQL Relay, SQLBits, SQL Saturdays, 24 HOP and the PASS Summit.This talk has taken place during Data Relay (formerly SQL Relay) conference in Reading (UK), on 11th October 2018 (Thursday). Interviewers: Kamil Nowinski.

Which unusual mean of transportation Alex use from time to time? Why monitoring of data quality does matter and what is the very efficient contrary of SCD in SSIS in BI loading process? Which skill is important if you want to jump into the IT market?Find out the answers on these questions and much, much more.Alex Whittles is the owner and principle consultant at Purple Frog, a SQL Server Business Intelligence consultancy in the UK with multinational clients in a variety of sectors. He specialises in all aspects of dimensional data modelling, data warehousing, ETL and cubes using the SQL Server stack.Alex has an MSc (Master of Science) in Business Intelligence, is a chartered engineer, and a member of Mensa. Community leadership includes being on the SQLBits committee, Director of SQL Relay, founder and leader of the Birmingham Data Platform user group.Alex is also a regular speaker at many SQL Server events around the world including SQL Relay, SQLBits, SQL Saturdays, 24 HOP and the PASS Summit.This talk has taken place during Data Relay (formerly SQL Relay) conference in Reading (UK), on 11th October 2018 (Thursday). Interviewers: Kamil Nowinski.

"Work can be a burden, or it can be a delight. How we view it depends on the choices that we make"   Our featured expert is a chartered psychologist who holds five degrees, including an MBA and a doctorate in occupational psychology. Describing himself as "the leader's psychologist", Dr. Jonathan Passmore explains how coaching can help individuals, teams and organisations identify and grow new momentum in both their professional and personal spheres.    THE DISCUSSION:  Dr. Passmore shares what he's learned from more than two decades of research and teaching, including: what makes a good coach how to make the best use of workplace coaching the myths of coaching what research reveals about its effectiveness He provides practical tips to help leading professionals become more 'centred', to develop better working practices internally and externally within the context of the accounting and finance sector. Finally, he also shares his recommended resource for further learning: “Coaching for Performance” by John Whitmore (5th Edition, 2018). Find out more about Jonathan at www.jonathanpassmore.com   == MORE ABOUT OUR PODCAST ==    DON'T MISS OUT. Get the latest show every week, automatically and free, at https://www.aicpa-cima.com/disruption.html. Share it easily with colleagues and friends by using the icons on the media player.  TAKE IT FURTHER. Find related CPD/CPE resources at https://www.aicpastore.com/GoBeyondDisruption and https://www.cgmastore.com/GoBeyonddisruption. STAY CONNECTED. Follow #GoBeyondDisruption, @AICPANews and @CIMA_News on social."   ©2018 Association of International Certified Professional Accountants (AICPA & CIMA). All rights reserved 

There is a long and successful record of fiction, especially science fiction, being instructive about history, human nature, and the eternal course of events.Fiction, of course, gets its inspiration from reality - a two way road.What do the Star Wars movies have to tell us about some of the comfortable myths we may see in American military and strategic thought?Using his latest article at the Modern War Institute, Star Wars and American Strategic Myths as a starting point, our guest for the full hour returning to Midrats will be Major Matt Cavanaugh, USA an active duty Army Strategist and nonresident fellow with the Modern War Institute at West Point. He’s been the youngest recipient of the Army Strategist Association’s highest professional award (in 2015), and was named the US Army’s Athlete of the Year (in 2009). He’s currently finishing a PhD on supreme command under Professor Colin Gray at the University of Reading (UK), and his writing has appeared in the New York Times, the Washington Post, and the Wall Street Journal, among other publications. His book, co-edited and co-written with Max Brooks (of World War Z) is Strategy Strikes Back: How Star Wars Explains Modern Military Conflict, from Potomac Books has been available since May 1st from Potomac Books.

Dr Jude Currivan is a cosmologist, planetary healer, futurist and author. She was previously one of the most senior business women in the UK and has a Master's degree in Physics from Oxford University specializing in quantum physics and cosmology, and a Doctorate in Archaeology from the University of Reading UK.. Dr.Currivan has travelled to nearly 80 countries, worked with wisdom keepers from many traditions, and been a life-long researcher into the scientific and experiential understanding of the nature of reality. She has authored six books, including her latest, The Cosmic Hologram: In-formation at the Center of Creation, she is a member of the Evolutionary Leaders circle. Visit www.judecurrivan.com and www.wholeworld-view.org. Get the Inclusion Revolution CD by Sister Jenna.  Like America Meditating.  Visit www.AmericaMeditating.org.  Download our free Pause for Peace App for Apple or Android

The 1980s might be getting some of its foreign policy back - but why is our entire defense framework in the second-half of the second decade of the 21st Century based around ideas forged when the Chrysler K-car was still a young platform?Is our present system creating the conditions for our uniformed senior leadership to forge the best path for our military to support national security requirements?Our guest for the full hour is returning to Midrats to discuss this and more; M.L. Cavanaugh. Matt and is a US Army Strategist with global experience in assignments ranging from the Pentagon to Korea and Iraq to his current post at US Army Space and Missile Defense Command. He’s a Non Resident Fellow with the Modern War Institute (MWI) at West Point, where he provides regular commentary and analysis. He’s also a contributor to War on the Rocks, and Matt’s writing has appeared in The New York Times, USA Today, the Chicago Tribune, and at ForeignPolicy.com, among other publications. After graduating from West Point in 2002, he earned his Master’s degree at Victoria University in Wellington, New Zealand, and is currently at work on a PhD dissertation on supreme command under Professor Emeritus Colin Gray at the University of Reading (UK). You can find more on Matt at MLCavanaugh.com and he can be reached via Twitter @MLCavanaugh. 

Ian Paget is a graphic designer based in Reading UK. He runs a part time freelance business called Logo Geek, designing logos as well as running a popular social media group of the same name. In his day job he works as a creative director. Show notes at http://hellotechpros.com/ian-paget-entrepreneurship/ Sponsors Minio Cloud Storage - Store photos, videos, VMs, containers, log files, or any blob of data as objects.

Soo Wincci – Musicpreneur talks about what it takes to create fame and fortune as she makes her first appearance in the US recording an new hit song with Award Winning Music Producer David Bendeth. How can you grow your business and your brand around the world? Trevor interviews multifaceted star, Miss World Malaysia 2008, Soo Wincci, who is a world renowned sensation, an award winning Malaysian singer, actress, composer, chef, host, model, beauty queen and also an entrepreneur. Crowned Miss World Malaysia 2008 Wincci represented Malaysia in the Miss World 2008 beauty pageant. In 2013, she was selected by Hollywood’s Independence Critics as the world Top 100 most beautiful women in the world. She is a law graduate from University of Reading (UK), MBA holder University of Sunshine Coast and currently also a PHD doctorate student in the field of Business Administration in Open University Malaysia. Soo Wincci is currently the owner of Beyond Artistes Sdn Bhd. To get her free gift, go to: www.greatnessquest.com/wincci

Today Ben talks about his hometown, Reading UK. He explains the history of the town and where the name comes from. He also tells us about the Reading (Music) Festival. Ben also gives us a sample of the local dialect. Words and expressions to listen for: Dynamic - Tokyo is a dynamic place to live. Cringe - 不愉快 - The sound of her voice makes me cringe. Commute - Taro commutes from Saitama to Tokyo every day. Mud - When it rains the ground turns to mud. To top oneself (commit suicide) - Kurt Cobain topped himself in 1994. Mate (friend) - I'm going out with my mates tonight.

Is the profession of arms, as the Navy believes it is, primarily a technical job for officers - or is it something else?To create the cadre of leaders one needs, do you train them as empty vessels that one only needs to fill up with what you want or an empty checklist to complete - or do you train them by helping them bring out their ability to lead and make decisions through informed critical thinking?Our guest for the full hour to discuss this and more will be Major Matt Cavanaugh, USA. Matt is currently assigned as an Assistant Professor in military strategy at the U.S. Military Academy at West Point. Prior to this assignment, Matt was a Strategic Planner at the Pentagon, after service with the with Second Squadron, Third Armored Cavalry Regiment with multiple deployments to Iraq from Fallujah, Ramadi, and Tal’Afar.Matt earned his Master’s in Strategic Studies at Victoria University in Wellington, New Zealand and is currently at work on a PhD dissertation on generalship at the University of Reading (UK). He is a Fellow at the Center for the Study of Civil Military Operations, has been published with several peer-reviewed military and academic journals, and is the Editor at WarCouncil.org, a site dedicated to the study of the use of force. Matt has represented the United States in an official capacity in ten countries, including: Iraq, Kuwait, Norway, Australia, New Zealand, Indonesia, Singapore, Malaysia, Latvia, and Great Britain. 

Dan Reynolds is a type designer and typographic researcher. Born in Baltimore, he studied graphic design at the Rhode Island School of Design, visual communication at the HfG Offenbach, and typeface design at the University of Reading (UK). After several years with the marketing and font development teams at Linotype GmbH, he founded his own design practice in Berlin, Germany. We talk with Dan about his first typographic memory. What got him interested in design and typography and how he ended up living in Germany. Although Dan comes from a family of academics, he prefers a more esthetic approach of type design. He would rather doodle letterforms and then worry about how they’re going to be used. Because Dan – while studying, teaching and working at a typefoundry as well as a freelance type designer and researcher – has seen almost every single aspect of the profession we wonder how all that knowledge on these different fields come together in his daily practice. Recorded at the Klingspor Museum Symposium – on the occasion of their 60th birthday – in Offenbach Germany. Type Off blog :: Dan at Linotype :: Christian Schwartz Deutsche Bahn :: Dan on Rudolph Koch :: Typostammtisch Offenbach :: File Download (21:59 min / 30 MB)

John was invited to play an alternative, non-D&B set of Electro & Techno at the monthly 'Cubed' night at Sub89 in Reading, with Jack Beats, back in December, and this is what he played. International Superstar DJ John B with Drum and Bass Electro RoboPunk Mixes recorded from his Live gigs all over the world, radio shows & interviews, studio mixes, and tour videos with behind the scenes footage, studio work and random tour adventures...