Podcasts about tuebingen

Send us a textDr. Nina Siragusa, Ph.D., MBA, is the Strategy, Business, and Data & Digital Lead within the global R&D organization of Merck Healthcare KGaA, Darmstadt, Germany. In this role, she leads strategic projects, manages business operations, and drives digital transformation.Previously, she served as Chief of Staff to Dr. Laura Matz, Chief Science and Technology Officer at Merck KGaA, Darmstadt, Germany. As part of the Science and Technology Office Leadership Team, she was responsible for fostering cross-sectoral collaboration, innovation, and digitalization across Merck's three business sectors. She also spearheaded the company's efforts in Bioconvergence, a multidisciplinary approach that synergizes biology, engineering, data, and digitalization. This initiative promises groundbreaking advancements in healthcare and the life sciences, heralding a new era of scientific collaboration for a healthier, more sustainable future.Prior to that, Dr. Siragusa contributed to corporate innovation in several leadership roles:• As Biotechnology Lead of a synthetic biology innovation project,• As Senior Manager, responsible for creating strategic alignment and building high-performing teams, and• As Associate Director, focusing on sourcing innovative ideas to generate new business opportunities.Dr. Siragusa earned her Ph.D. in Biology from the University of Tuebingen, Germany, and conducted research in Europe and the USA, including at Yale University, before joining Merck KGaA, Darmstadt, Germany in 2016.In 2024, she completed an MBA in Digital Transformation Management with a focus on Digital Leadership at Goethe Business School, Frankfurt, Germany.Dr. Siragusa is also the lead author of the recently published book, Bioconvergence Revolution: Challenges and Opportunities in Research Productivity. You can find it here: https://link.springer.com/book/10.1007/978-3-031-61593-1Home Page Merck KGaA Darmstadt, Germany - https://www.emdgroup.com/en#NinaSiragusa #EMDGroup #MerckKGaADarmstadtGermany #Bioconvergence #Ethics #Collaboration #Fungi #NaturalProducts #Biomimicry #AI #DrugDiscovery #Bioremediation #TranslationalMedicine #SmartManufacturing #DigitalTwins #Supermind #MIT #ResearchFunding #Israel #STEM #Innovation #Science #Technology #Research #ProgressPotentialAndPossibilities #IraPastor #Podcast #Podcaster #Podcasting #ViralPodcastSupport the show

When New Hampshire voters picked up the phone earlier this year and heard what sounded like the voice of President Joe Biden asking them not to vote in that state's primary election, the stage was set for an unprecedented election year. The call was a deepfake — and the first major instance of artificial intelligence being used in the 2024 election. With the rise of AI tools that can credibly synthesize voices, images and videos, how are voters supposed to determine what they can trust as they prepare to cast their votes?To find out how lawmakers and civil society are pushing back against harmful false narratives and content, we talked with experts engaging the problem on several fronts. Stephen Richer, an elected Republican in Phoenix, posts on X (formerly Twitter) to engage misinformation head-on to protect Arizona voters. Adav Noti, the executive director of CLC, explains how good-governance advocates are hurrying to catch up with a profusion of new digital tools that make the age-old practices of misinformation and disinformation faster and cheaper than ever. And Mia Hoffman, a researcher who looks at the effects of AI on democracies, reminds voters not to panic — that bad information and malicious messaging don't always have the power to reach their audience, let alone sway people's opinions or actions.Host and Guests:Simone Leeper litigates a wide range of redistricting-related cases at CLC, challenging gerrymanders and advocating for election systems that guarantee all voters an equal opportunity to influence our democracy. Prior to arriving at CLC, Simone was a law clerk in the office of Senator Ed Markey and at the Library of Congress, Office of General Counsel. She received her J.D. cum laude from Georgetown University Law Center in 2019 and a bachelor's degree in political science from Columbia University in 2016.Stephen Richer is the 30th Recorder of Maricopa County.  He was elected in November 2020 and took office in January 2021. His office of approximately 150 employees records hundreds of thousands of public documents every year, maintains a voter registration database of 2.4 million voters -- the second largest voting jurisdiction in the United States -- and administers the mail voting component of all elections in Maricopa County. Prior to his time as Recorder, Stephen worked in various business sectors and, later, as an attorney at the law firms Steptoe & Johnson LLP and Lewis Roca LLP.  He holds a J.D. and M.A. from The University of Chicago and a B.A. from Tulane University.  He is completing his PhD at Arizona State University.Adav Noti is Executive Director at Campaign Legal Center. He has conducted dozens of constitutional cases in trial and appellate courts and the United States Supreme Court. He also advises Members of Congress and other policymakers on advancing democracy through legislation. Prior to joining CLC, Adav served for more than 10 years in nonpartisan leadership capacities within the Office of General Counsel of the Federal Election Commission, and he served as a Special Assistant United States Attorney for the District of Columbia. Adav regularly provides expert analysis for television, radio, and print journalism. He has appeared on broadcasts such as The Rachel Maddow Show, Anderson Cooper 360, PBS NewsHour, and National Public Radio's Morning Edition, and he is regularly cited in publications nationwide, including the New York Times, Washington Post, USA Today, Politico, Slate, and Reuters.Mia Hoffmann is a Research Fellow at Georgetown's Center for Security and Emerging Technology. Her research focuses on AI harm incidents, aiming to provide a deeper understanding of failure modes and the efficacy of risk mitigation practices. In recent work, she examined the uses of AI in US election administration and their risks to electoral integrity. Prior to joining CSET, Mia worked at the European Commission and as a researcher in Brussels, where she studied AI adoption and its implications. She holds a MS in Economics from Lund University and a BS in International Economics from the University of Tuebingen. Links:How Artificial Intelligence Influences Elections, and What We Can Do About It - Campaign Legal CenterHow 2024 presidential candidates are using AI inside their election campaigns - CNBCNonprofit group plans ad campaign using AI misinfo to fight AI misinfo - PoliticoCLC Op-Ed Examines Artificial Intelligence Disinformation in Elections - Campaign Legal CenterCongress should pass bipartisan bills to safeguard elections from AI - Campaign Legal CenterAdditional InformationDemocracy Decoded PodcastMore shows from The Democracy Group

When New Hampshire voters picked up the phone earlier this year and heard what sounded like the voice of President Joe Biden asking them not to vote in that state's primary election, the stage was set for an unprecedented election year. The call was a deepfake — and the first major instance of artificial intelligence being used in the 2024 election. With the rise of AI tools that can credibly synthesize voices, images and videos, how are voters supposed to determine what they can trust as they prepare to cast their votes?To find out how lawmakers and civil society are pushing back against harmful false narratives and content, we talked with experts engaging the problem on several fronts. Stephen Richer, an elected Republican in Phoenix, posts on X (formerly Twitter) to engage misinformation head-on to protect Arizona voters. Adav Noti, the executive director of CLC, explains how good-governance advocates are hurrying to catch up with a profusion of new digital tools that make the age-old practices of misinformation and disinformation faster and cheaper than ever. And Mia Hoffman, a researcher who looks at the effects of AI on democracies, reminds voters not to panic — that bad information and malicious messaging don't always have the power to reach their audience, let alone sway people's opinions or actions.Host and Guests:Simone Leeper litigates a wide range of redistricting-related cases at CLC, challenging gerrymanders and advocating for election systems that guarantee all voters an equal opportunity to influence our democracy. Prior to arriving at CLC, Simone was a law clerk in the office of Senator Ed Markey and at the Library of Congress, Office of General Counsel. She received her J.D. cum laude from Georgetown University Law Center in 2019 and a bachelor's degree in political science from Columbia University in 2016.Stephen Richer is the 30th Recorder of Maricopa County.  He was elected in November 2020 and took office in January 2021. His office of approximately 150 employees records hundreds of thousands of public documents every year, maintains a voter registration database of 2.4 million voters -- the second largest voting jurisdiction in the United States -- and administers the mail voting component of all elections in Maricopa County. Prior to his time as Recorder, Stephen worked in various business sectors and, later, as an attorney at the law firms Steptoe & Johnson LLP and Lewis Roca LLP.  He holds a J.D. and M.A. from The University of Chicago and a B.A. from Tulane University.  He is completing his PhD at Arizona State University.Adav Noti is Executive Director at Campaign Legal Center. He has conducted dozens of constitutional cases in trial and appellate courts and the United States Supreme Court. He also advises Members of Congress and other policymakers on advancing democracy through legislation. Prior to joining CLC, Adav served for more than 10 years in nonpartisan leadership capacities within the Office of General Counsel of the Federal Election Commission, and he served as a Special Assistant United States Attorney for the District of Columbia. Adav regularly provides expert analysis for television, radio, and print journalism. He has appeared on broadcasts such as The Rachel Maddow Show, Anderson Cooper 360, PBS NewsHour, and National Public Radio's Morning Edition, and he is regularly cited in publications nationwide, including the New York Times, Washington Post, USA Today, Politico, Slate, and Reuters.Mia Hoffmann is a Research Fellow at Georgetown's Center for Security and Emerging Technology. Her research focuses on AI harm incidents, aiming to provide a deeper understanding of failure modes and the efficacy of risk mitigation practices. In recent work, she examined the uses of AI in US election administration and their risks to electoral integrity. Prior to joining CSET, Mia worked at the European Commission and as a researcher in Brussels, where she studied AI adoption and its implications. She holds a MS in Economics from Lund University and a BS in International Economics from the University of Tuebingen. Links:How Artificial Intelligence Influences Elections, and What We Can Do About It - Campaign Legal CenterHow 2024 presidential candidates are using AI inside their election campaigns - CNBCNonprofit group plans ad campaign using AI misinfo to fight AI misinfo - PoliticoCLC Op-Ed Examines Artificial Intelligence Disinformation in Elections - Campaign Legal CenterCongress should pass bipartisan bills to safeguard elections from AI - Campaign Legal CenterAbout CLC:Democracy Decoded is a production of Campaign Legal Center, a nonpartisan nonprofit organization which advances democracy through law at the federal, state and local levels, fighting for every American's right to responsive government and a fair opportunity to participate in and affect the democratic process. Learn more about us.Democracy Decoded is part of The Democracy Group, a network of podcasts that examines what's broken in our democracy and how we can work together to fix it.

Rainer Funk is Director of the Erich Fromm Institute Tuebingen, Co-Director of the Erich Fromm Study Center at the International Psychoanalytic University (IPU) in Berlin, and a practicing psychoanalyst based in Tuebingen, Germany. He is Erich Fromm's sole Literary Executor and among his publications are the 10-volume German edition of Erich Fromm Collected Works (1980 and 1981; expanded to 12-volumes in 1999). In this episode, we discuss the first time Rainer met Erich Fromm, Fromm's nuanced approach to religion, Fromm's relevance for the 21st century and much more.

In this episode, we delve into the spunky, bright, and warm world of Conny Goelz Schmitt, a renowned collage artist and sculptor whose work is deeply influenced by her rich multicultural experiences. Conny's journey spans continents, from her upbringing in Germany to her time in Taiwan and eventual settling in the United States. She seamlessly integrates elements of her diverse cultural background through her art, drawing inspiration from German artistry's meticulous attention to detail, the vibrant retro aesthetics of 1980s Taiwan, and the boundless creativity of the American pioneering spirit. Her profound connection with vintage books lies at the core of Conny's artistic expression. She shares her evolution from 2D collages to intricate 3D sculptures, experimenting with various levels of complexity and materials such as wallpaper and enamel. Despite exploring different mediums, Conny's unwavering dedication to books as her primary medium remains unwavering. For her, books serve as a conduit for time travel, bridging the past with the future and igniting a continuous stream of creative ideas. During our conversation, Conny reflects on her recent residency in Pouch Cove, delving into the projects she worked on and the inspiration she drew from the serene coastal surroundings. We explore the underlying reasons behind her choice of books as a medium and her profound attachment to them, prompting her to question the essence of her creative journey and the inexhaustible wellspring of ideas that fuels her passion. Finally, we discuss Conny's unique perspective on cultural similarities from her immersive experiences in Germany, Taiwan, and the United States. Through her keen observations, she unveils unexpected connections that transcend geographical boundaries, highlighting the universal language of art that resonates across diverse cultures. Conny is a joy, and I hope you enjoy this conversation! Topics discussed: • Cultural Fusion in Art: • The Timeless Medium of Vintage Books • Exploring Creativity and Collaboration. About Conny: Conny Goelz Schmitt is a collage artist and sculptor who spent her youth in Germany, moved to Taiwan in her twenties, and relocated to the US in 1996. Having been immersed in three very different cultures, she is drawn to hard edge painting influenced by the German “attention to detail”, the retro color palette reminiscent of Taiwan in the 80s, and the very often experimental and creative pioneering spirit of Americans. Her medium of choice is almost without exception the vintage book. In Germany she studied Sinology and German Literature at Eberhard Karls University in Tuebingen. She was named Sculptor of the Year by Chief Curator of Boston University, Kate McNamara in CAA's 69th Members' Prize Show. In 2016, Paul C. Ha, Director of the List Visual Art Center at Massachusetts Institute of Technology, selected her work for the Best Multi Media Prize in CAA's National Prize Show. She was awarded a fellowship to the Vermont Studio Center for 2020. Besides exhibiting at Kathryn Markel Fine Arts, New York, NY and Hidell Brooks Gallery in Charlotte, her work has been featured at Galerie Biesenbach, Cologne (Germany), the Cultural Association of Rosa Venerini, Viterbo (Italy), The Painting Center, New York, Site: Brooklyn, New York, The Danforth Art Museum, Framingham, MA, among others. Conny has a studio in Beverly, Massachusetts. Connect with Conny Gölz Schmitt Conny's Instagram Conny's Website Connect with Stephanie Instagram: @stephaniegraham @noseyafpod Check out my art and projects More Episodes at noseyaf.com Leave me feedback or send me a message Support the Show! Rate and Review the show Share noseyAF with your friends  Buy a pin  Buy a print Get the noseyAF newsletter Sponsorship Opportunities

Thomas Craemer obtained a political science doctorate in 2001 from the University of Tuebingen in his native Germany, and a PhD from Stony Brook University, New York, in 2005. He teaches at the University of Connecticut's Department of Public Policy. His experience of growing up in post-World-War II Germany motivated his research on implicit racial […]

Thomas Craemer obtained a political science doctorate in 2001 from the University of Tuebingen in his native Germany, and a PhD from Stony Brook University, […]

Jens is a psychologist working in collaboration with HMPPS to understand online radicalisation. 'One of the more sobering findings is the prevalence of mental health issues (in the widest sense) among those labelled as radicalised extremists. Prevalence is quite high, and it is highest among those who got radicalised through online influences. And, as many have expected, autism spectrum condition is at the top of the list, but is by no means the only entry.' Jens is Associate Professor of Psychology and a member of the Department of Psychology in the School of Social Sciences. Jens is currently course leader for the MSc Cyberpsychology. In the past, he has been a course leader at the UG level and an Associate Course Leader for the Professional Doctorate in Forensic Psychology. His teaching focuses on Social Psychology and Cyberpsychology. He also regularly supervises 3rd year dissertations, Masters projects and PhD-level projects.   Jens studied at the Universities of Tuebingen, Germany and Massachusetts, US. He completed his doctoral work in 2005 in the area of small group decision-making and negotiation under the supervision of Michael Diehl.

Giovedì 27 luglio 2023, ore 21.00, in diretta la 31^ puntata del Daddo Triathlon Show per parlare con competenza, e anche un pizzico di ironia, dell'attualità del mondo della triplice.Dario Daddo Nardone "moderator", opinionista il Marabaus, in arte Massimo Marabese, temi della puntata:#vaginauncensoredLa magia di eagleXman, ancora immensa Fabia Maramotti, inarrestabile Lorenzo Facelli, più di 200 in tutti i finisher di Campo Imperatore!La decima candelina dell'XTERRA Lake Scanno viene spenta da Michele "The Shark" Bonacina (grande squalo, primo italiano a vincere a Scanno tra gli Elite!) e Carina WasleChiara Lobba vince anche il Triathlon Silca Cup Alpago, Marco Barison più veloce tra gli uominiLa due giorni di Bracciano con la tappa Italiana Paratriathlon Series e lo sprint vinto da Sara Balletta e Riccardo SpanuIl primo Triathlon Super Sprint Città di Potenza per tutte le età, Emanuela Annunziata e Federico Mazzei primi classificatiL'Aquathlon Città di Vercurago di Krono Lario Team dedicato ai giovaniBravo il nostro azzurro Giovanni Aruffo, è sua la medaglia d'argento all'Europe Triathlon Junior Cup di TaborIl talento della magiara Fanni Szalai brilla anche all'Europe Triathlon Youth Championships Festival Banyoles FinalLisa Tertsch e Simon Westermann vincono la tappa di Tuebingen della Bundesliga Triathlon, bravo Nick Ragazzo 8° assolutoLionel Sanders torna a vincere all'Ironman 70.3 Oregon, imitato da Danielle LewisAlistair Brownlee non parte, Ironman Lake Placid e slot per i Mondiali a Joe Skipper, oro donne per Alice AlbertsLe gare del prossimo week end, focus su:All'Ironman 70.3 Maine Greg e Giorgia scaldano i modori per la PTO US Open della settimana dopoGli azzurri alla World Triathlon Championship Series SunderlandLo spettacolo dell'Alpe d'Huez TriathlonL'Aronamen, i triathlon sprint di Brescia ed Empoli e l'Aquathlon del TricoloreLe ultime sulla PTO US Open del 4 e 5 agosto (star list e wild card, ci saranno Giorgia e Greg!) e la PTO Asian Open di Singapore del 19 e 20 agosto... E molto altro!Tutte le puntate del Daddo Triathlon Show qui: https://www.mondotriathlon.it/daddoSostieni il tuo Mondo Triathlon: https://bit.ly/donatri#daddocè #mondotriathlon #ioTRIamo ❤️#triathlon #trilife #fczstyle #passionetriathlon

This is Beauty Podcast Thurs., Aug. 25, 2022 Episode 2: Beauty and the Human Brain with Aenne Brielmann, Ph.D. If you've wondered why you find some things beautiful, but not others, or why your experiences of Beauty don't always agree with those of your spouse, siblings, lover or friends, then this show is for you. As it so happens, there's real science behind the reasons for our individual perceptions of beauty. The old adage about beauty being, "in the eye of the beholder", stays with us for a reason -- as we learn in this interview with Doctor Aenne Brielmann. Aenne is a researcher at the Max Planck Institute for Biological Cybernetics in Tuebingen, Germany where she studies aesthetic value and the experience of Beauty. Her work seeks to answer some of the more complex questions around aesthetic experience, and to help us understand how and why we experience the very feeling of Beauty itself What is Beauty exactly? Where does the feeling of Beauty come from, and why do humans experience Beauty in the first place? In this episode of This is Beauty Podcast, we find out what researchers have learned so far about the experience of Beauty and the human brain. We also talk about the critical links between Beauty and pleasure, and learn how our internal states affect our ability to experience Beauty in the first place. Topics covered in this episode include: the importance of Beauty as a survival mechanism in humans differences between types of Beauty experiences, including music, taste, sight, smell, feelings, and more how sharing beautiful experiences with others amplifies our own experiences of Beauty why feelings of depression may limit our ability to recognize Beauty small changes we can make to increase the impact and frequency of beautiful experiences how increasing our sensitivity to Beauty might help us lead healthier, happier lives the possible connections between Beauty and artificial intelligence To learn more about the ideas and information contained in this interview, or today's guest, please check out these following links and resources: GUEST BIO Aenne Brielmann, Ph.D.  Aenne Brielmann, PhD is a scientist and postdoctoral fellow at the https://www.kyb.tuebingen.mpg.de/person/58620/2549 (Max-Planck Institute for Biological Cybernetics in Tuebingen), Germany where she investigates the experience of aesthetic value. Her research, which expands upon her original investigation into the experience of beauty in humans, seeks to understand the rules governing aesthetic choice in humans from a psychological perspective, while also incorporating computational neuroscience, machine-and reward-learning perspectives.  Aenne is a graduate of University of Konstanz and a former resident of New York City where she completed her PhD in psychology at NYU. Her work has been covered by the Smithsonian Magazine, and has also appeared in numerous journals including the Journal of Vision, Current Biology and Frontiers in Psychology.   To learn more about Aenne and her work, visit her site at https://aenneb.github.io (https://aenneb.github.io) LINKS Website: https://aenneb.github.io/ Research: https://aenneb.github.io/research/ (https://aenneb.github.io/research/) Max Planck: https://www.kyb.tuebingen.mpg.de/person/58620/2549 (https://www.kyb.tuebingen.mpg.de/person/58620/2549) LISTEN, FOLLOW & SUBSCRIBE https://feeds.captivate.fm/this-is-beauty-podcast/ (This Is Beauty Podcast ) https://feeds.captivate.fm/this-is-beauty-podcast/ https://www.thisisbeautypodcast.com/ (This is Beauty Podcast Website) https://www.thisisbeautypodcast.com/ https://www.thisisbeautypodcast.com/contact/ (This Is Beauty Mailing List) https://www.thisisbeautypodcast.com/contact/ https://www.instagram.com/thisisbeautypodcast/ (Instagram ) https://www.instagram.com/thisisbeautypodcast/ https://www.facebook.com/ThisIsBeautyPodcast (Facebook) https://www.facebook.com/ThisIsBeautyPodcast

Jay's Top 5 CliftonStrengths are: LEARNER, IDEATION, CONNECTEDNESS, STRATEGIC & CONTEXT   Driven by a commitment to multiplying discipleship, Jay and his wife Laurie constantly dream of creative learning and leadership development venues for King and Kingdom. They want to be a voice for forgotten leaders.   Jay and Laurie Lorenzen have served with several missionary orders for 45 years - 20 years associate staff with Cru Military, 25 years full-time staff with Cru/Campus Crusade for Christ, and for the last three years with Global Service Associates.   Before beginning full-time missionary work, Jay spent his last 12 years of active duty military as an Associate Professor of Political Science at the Air Force Academy—during which he and Laurie began the Cru Military movement there.    Prior to his Academy assignment, Jay was a KC-135 Navigator for four years before being selected for an Olmsted Fellowship at Tuebingen Universitat in Germany. After studying in Tuebingen, Jay attended Fletcher School of Law and Diplomacy at Tufts University for his MA, followed by a Ph.D. sponsorship at the University of Denver.    After he retired, he completed an MDiv at Denver Seminary.   Now, in addition to serving with the Cru's Military Ministry and Faculty Commons (Cru's ministry to faculty), Jay and Laurie helped lead the informal Gospel in Action initiative within the US Campus Ministry—attempting to wed together the bold proclamation and compassionate demonstration of the gospel into local movements.    He and his wife Laurie have also directed the “If Properly Led Leadership Development Conference” at Gettysburg, PA (see ifproperlyled.org, now called  [thehighgroundatgettysburg.org](http://thehighgroundatgettysburg.org/) ) for the last 25 years.   Jay and Laurie have four married children and 15 grandchildren.    When not traveling, Jay and Laurie live in Lake George, CO, near the Tarryall River, an excellent trout stream. You can follow Jay at jaylorenzen on instagram

Helene Sader talked about the history of Phoenicia; the alphabet, culture, and important figures.Helene Sader has been a Professor of Archaeology at AUB since 2001. She received her PhD from the University of Tuebingen 1984. Sader specializes in the archaeology of the Levant, mainly the Iron Age, and in northwest Semitic epigraphy. She acts as co-director of the Beirut 020, Tell el-Burak and Tell Kubba projects.Created by Mikey Muhanna In Partnership with Heritage & RootsHosted by Charles Al Hayek Edited by: Ramzi RammanTheme music by: Firas Zreik; "Refractions" Performed Live on afikra Quartertones.About Mujalasa:Mujalasa is a platform for exchanging ideas, debating academia, and building intellectual curiosity for the purpose of enlightenment. An Arabic podcast series exploring the histories of the region, hosted by Charles Al Hayek from Heritage & Roots and powered by afikra. Following the interview, there is a moderated town-hall-style Q&A with questions coming from the live virtual audience ‎on Zoom.‎ Join the live audience: https://www.afikra.com/rsvp   FollowYoutube - Instagram (@afikra_) - Facebook - Twitter Support www.afikra.com/supportAbout afikra:‎afikra is a movement to convert passive interest in the Arab world to active intellectual curiosity. We aim to collectively reframe the dominant narrative of the region by exploring the histories and cultures of the region- past, present, and future - through conversations driven by curiosity. Read more about us on  afikra.com 

On this episode, the hosts are joined by Dr. Gillian Wong, who shares her passion and research for microfauna and reconstructing the paleoenvironment through zooarchaeology. We delve into her post-doctoral research at Langmahdhalde for the University of Tuebingen, Germany, share our pandemic woes at limiting research possibilities, and talk about the amazing role the bones... Continue Reading → The post Zooarchaeology, Microfauna Fun, and Career Flexibility with Dr. Gillian Wong appeared first on Women In Archaeology.

This month, Jessica Tizzard (University of Tuebingen) makes her second appearance on Elucidations to talk to Matt about pregnancy.Human pregnancy is weird. Try talking to a reproductive endochrinologist about it, and you'll soon find that there's a lot we don't really understand about it even at the scientific level. But even when it comes to thinking about pregnancy at the commonsense reasoning level, puzzles begin popping up the second you start trying to think about it systematically. Like, consider the commonsense idea that a fetus is ‘inside' the person who is pregant with it. They clearly are, in the sense that they aren't out and about in the world the way a marsupial fetus is. But if you think about how containment and interiority are defined mathematically, there's also a sense in which the fetus can't literally be inside the womb, because in order for one thing to be inside another they have to be physically disconnected.In this episode, Jessica Tizzard argues that our commonsense thinking about pregnancy is dominated by ‘container' metaphors: i.e. we think about a fetus inside a womb the way we think about a cookie inside a jar. However, she thinks that ‘parthood' analogies are often an equally good fit for how a fetus relates to the person pregnant with it. That is, there are also biological analogies you could draw between a fetus and a body part: a body part is seamlessly physically connected to the body it's a part of, and a body part is subject the same organism-level system of homeostatic regulation that the rest of the body is.The next step is to start thinking about how these observations ramify morally. Can acknowledging that the ‘parthood' way of thinking is at least as biologically accurate as the ‘container' way of thinking help shed light on what kinds of duties a pregnant person has to their as-yet unborn fetus? Join Matt and Jessica as they dive right into these thorny but important questions!Further ReadingOur distinguished guest recommends the following literature on pregnancy, which she draws on heavily in her own work:‘Lady Parts', Elselijn Kingma‘Were You a Part of Your Mother?', Elselijn Kingma‘9 Months', Elselijn Kingma‘Neonatal Incubator or Artifical Womb?', Elselijn Kingma and Suki Finn‘Abortion, Intimacy, and the Duty to Gestate', Margaret Olivia LittleHappy reading!Matt Teichman See acast.com/privacy for privacy and opt-out information.

Guest Samuel Wein Panelists Richard Littauer | Justin Dorfman Show Notes Hello and welcome to Sustain! The podcast where we talk about sustaining open source for the long haul. On today's episode, we are very excited to have as our guest, Samuel Wein, who is a core developer and Executive Chairman of the OpenMS Foundation, a Post Doc at University of Tuebingen in Germany, and the head of a software consultancy specializing in analysis of RNA using Mass Spectrometry. Samuel fills us in on OpenMS and Mass Spectrometry and how he's trying to make it better and expand it. He explains more about the governance process, how the funding process is going, training programs he's done, and an internship program in the works to get more diversity. Samuel shares some great groups to get involved in the open source projects sciences area, and what he would like to change with OpenMS. Go ahead and download this episode now to find out more! [00:02:14] Samuel is a scientist, so we find out how he ended up being a coder. [00:03:27] Samuel explains OpenMS and Mass Spectrometry, and Justin wonders if this was instrumental in the mRNA research from Moderna and the other place that Pfizer teamed up with. [00:06:47] Justin wonders how many times Samuel has been trying to get recruited from companies, such as Moderna, since they are probably looking for people like Samuel, and what's keeping him away from them. [00:08:14] Richard wonders what the governance process was like. [00:11:09] Samuel has three partnerships for funding right now and Justin wonders if they are his go-to or if he needs to get more funding from different partners. [00:13:08] Richard asks Samuel if he can talk about how he's keeping the project from ending up bending the corporate interest and what it looks like for him. [00:14:29] Justin wonders what other revenue streams Samuel has besides his donors and grants and if he has any training programs that he's put together. [00:17:34] Besides documentation, Richard is curious to know if Samuel could think of looking at his organization and then the wider field as a whole of really improving JEDI work, and if there's anything he's working on besides that. [00:20:00] Samuel explains how people can get involved and what was helpful for him. [00:22:17] We find out what Samuel is interested in learning and changing, as well as other things he's interested in doing with OpenMS. [00:24:07] Samuel suggests some groups that have useful to him to join, such as Open Bio, EuBIC-MS, and HUPO PSI. [00:25:45] Find out where you can follow Samuel on the internet. Quotes [00:08:19] “My experience with scientific projects developed in labs is that they unfortunately tend to have a lifecycle that is contingent upon the career path of the core developer.” [00:08:45] "There are issues with sustainability and maintainability once the original developer has left.” [00:09:39] “[On community organizing in OSS] It's all volunteer, it's all passion projects, and you need to steer people towards their passions.” [00:16:20] “We're looking for a Community Manager.” [00:22:41] “I would like to convince more scientists of the importance of choosing their software based on it's openness.” Spotlight [00:27:23] Justin's spotlight is BioJS. [00:27:56] Richard's spotlight is _The Wheel of Time _books by Robert Jordan. [00:28:45] Samuel's spotlight is Anathem by Neal Stephenson. Links SustainOSS (https://sustainoss.org/) SustainOSS Twitter (https://twitter.com/SustainOSS?ref_src=twsrc%5Egoogle%7Ctwcamp%5Eserp%7Ctwgr%5Eauthor) SustainOSS Discourse (https://discourse.sustainoss.org/) Samuel Wein PhD Linkedin (https://www.linkedin.com/in/samuel-wein-phd-20700323) Samuel Wein GitHub (https://github.com/poshul) OpenMS (https://www.openms.de/) sam@samwein.com (mailto:sam@samwein.com) Otakon (https://www.otakon.com/) Open Bioinformatics Foundation (https://www.open-bio.org/) EuBIC-MS (European Bioinformatics Community for Mass Spectrometry) (https://eubic-ms.org/) HUPO-PSI (HUPO Proteomics Standards Initiative) (https://psidev.info/) BioJs (https://biojs.net/#/) [The Eye of the World: Book One of The Wheel of Time by Robert Jordan](https://www.amazon.com/Eye-World-Book-Wheel-Time/dp/1250832365/ref=sr14?keywords=the+wheel+of+time&qid=1639498260&sr=8-4) [Anathem by Neal Stephenson](https://www.amazon.com/Anathem-Neal-Stephenson/dp/006147410X/ref=sr13?crid=16WXX28YH3HTQ&keywords=neil+stevenson+books&qid=1639498801&sprefix=neil+ste%2Caps%2C190&sr=8-3) Credits Produced by Richard Littauer (https://www.burntfen.com/) Edited by Paul M. Bahr at Peachtree Sound (https://www.peachtreesound.com/) Show notes by DeAnn Bahr Peachtree Sound (https://www.peachtreesound.com/) Special Guest: Samuel Wein.

Today, Denise engages in the second part of her dynamic interview with guest David A. Fiensy. They continue to discuss the cultural context of Jesus' parables and how these lessons apply to our lives today. David is the author of Hear Today: Compassion and Grace in the Parables of Jesus. Author Bio: David A. Fiensy has a passion for teaching and preaching the Bible and for thinking about and articulating theological ideas. After graduating from Duke University with a Ph.D. in New Testament and Second Temple Judaism, David Fiensy taught for seven years at Kentucky Christian University. He then served a two-year tenure at the Institut zur Erforschung des Urchristentums in Tuebingen, Germany. Upon returning to the United States, he accepted a church pastorate for six years and then resumed teaching at Kentucky Christian University. He has participated in seven archaeological excavations and surveys and has otherwise traveled widely in the Mediterranean area and the Middle East. Now semi-retired, David serves as a speaker and consultant for churches and colleges and is involved in several writing and research projects. David and his wife, Molly, have two daughters and three grandchildren. You can connect with David at https://davidafiensy.com/.

In this episode, we are joined by Dr. Gillian Wong, who is an Adjunct Professor of Anthropology at Metropolitan Community College in Kansas City, Missouri, and a postdoctoral researcher at the University of Tuebingen. Dr. Wong chats with us about her early outdoor days, experiences at UC Davis, and how learning French has been useful for her in archaeology. We then delve into her thesis/dissertation work at the University of Utah and then in Germany. She pronounces the name of the site she worked on and Connor/Carlton fails to replicate her pronunciation. Dr. Wong then talks about her experiences being a military spouse and also some advice for those who are military spouses. Literature Recommendations 2008 The Archaeology of Animal Bones by Terry O'Connor 2017 Human Subsistence and Environment during the Magdalenian at Langmahdhalde: Evidence from a new Rock Shelter in the Lone Valley, Southwest Germany by Wong, Gillian L., Starkovich, B. M., Conard, N. J. 2018 An Introduction to Zooarchaeology by Diane Gifford-Gonzalez 2016 Taphonomy for Taxonomists: Implications of predation in small mammal studies by Fernández-Jalvo, Y., Andrews, P., Denys, C., Sesé, C., Stoetzel, E., Marin-Monfort, D., Pesquero, D. 2019 Mothering from the Field: The Impact of Motherhood on Site-Based Research edited by Bahiyyah M. Muhammad and Melanie-Angela Neuilly 2020 New perspectives on human subsistence during the Magdalenian in the Swabian Jura, Germany by Wong, Gillian L., Starkovich, B. M., Drucker, D. G., Conard 2020 Latest Pleistocene paleoenvironmental reconstructions from the Swabian Jura, southwestern Germany: evidence from stable isotope analysis and micromammal remains by Wong, Gillian L., Drucker, D. G., Starkovich, B. M., Conard, N. J. Dr. Wong's Recorded lecture on her work at Langmahdhalde Holding down the Fort Podcast Guest Contact Twitter @GillianLWong Email: gillian.wong368@gmail.com Contact Email: alifeinruinspodcast@gmail.com Instagram: @alifeinruinspodcast Facebook: @alifeinruinspodcast Twitter: @alifeinruinspod Website: www.alifeinruins.com Ruins on APN: https://www.archaeologypodcastnetwork.com/ruins Store: https://www.redbubble.com/people/alifeinruins/shop ArchPodNet APN Website: https://www.archpodnet.com APN on Facebook: https://www.facebook.com/archpodnet APN on Twitter: https://www.twitter.com/archpodnet APN on Instagram: https://www.instagram.com/archpodnet Tee Public Store Affiliates Wildnote TeePublic Timeular

In this episode, we are joined by Dr. Gillian Wong, who is an Adjunct Professor of Anthropology at Metropolitan Community College in Kansas City, Missouri, and a postdoctoral researcher at the University of Tuebingen. Dr. Wong chats with us about her early outdoor days, experiences at UC Davis, and how learning French has been useful for her in archaeology. We then delve into her thesis/dissertation work at the University of Utah and then in Germany. She pronounces the name of the site she worked on and Connor/Carlton fails to replicate her pronunciation. Dr. Wong then talks about her experiences being a military spouse and also some advice for those who are military spouses. Literature Recommendations 2008 The Archaeology of Animal Bones by Terry O'Connor 2017 Human Subsistence and Environment during the Magdalenian at Langmahdhalde: Evidence from a new Rock Shelter in the Lone Valley, Southwest Germany by Wong, Gillian L., Starkovich, B. M., Conard, N. J. 2018 An Introduction to Zooarchaeology by Diane Gifford-Gonzalez 2016 Taphonomy for Taxonomists: Implications of predation in small mammal studies by Fernández-Jalvo, Y., Andrews, P., Denys, C., Sesé, C., Stoetzel, E., Marin-Monfort, D., Pesquero, D. 2019 Mothering from the Field: The Impact of Motherhood on Site-Based Research edited by Bahiyyah M. Muhammad and Melanie-Angela Neuilly 2020 New perspectives on human subsistence during the Magdalenian in the Swabian Jura, Germany by Wong, Gillian L., Starkovich, B. M., Drucker, D. G., Conard 2020 Latest Pleistocene paleoenvironmental reconstructions from the Swabian Jura, southwestern Germany: evidence from stable isotope analysis and micromammal remains by Wong, Gillian L., Drucker, D. G., Starkovich, B. M., Conard, N. J. Dr. Wong's Recorded lecture on her work at Langmahdhalde Holding down the Fort Podcast Guest Contact Twitter @GillianLWong Email: gillian.wong368@gmail.com Contact Email: alifeinruinspodcast@gmail.com Instagram: @alifeinruinspodcast Facebook: @alifeinruinspodcast Twitter: @alifeinruinspod Website: www.alifeinruins.com Ruins on APN: https://www.archaeologypodcastnetwork.com/ruins Store: https://www.redbubble.com/people/alifeinruins/shop ArchPodNet APN Website: https://www.archpodnet.com APN on Facebook: https://www.facebook.com/archpodnet APN on Twitter: https://www.twitter.com/archpodnet APN on Instagram: https://www.instagram.com/archpodnet Tee Public Store Affiliates Wildnote TeePublic Timeular

For the last half of the month, Denise rounds off the discussion of God's gifts to us for Christmas and the year round as she interviews guest David Fiensy. Listen in as they discuss biblical context of the parables of Jesus and what a gift His Word is to us.  Author Bio: David Fiensy has a passion for teaching and preaching the Bible and for thinking about and articulating theological ideas. After graduating from Duke University with a Ph.D. in New Testament and Second Temple Judaism, David Fiensy taught for seven years at Kentucky Christian University. He then served a two-year tenure at the Institut zur Erforschung des Urchristentums in Tuebingen, Germany. Upon returning to the United States, he accepted a church pastorate for six years and then resumed teaching at Kentucky Christian University. He has participated in seven archaeological excavations and surveys and has otherwise traveled widely in the Mediterranean area and the Middle East. Now semi-retired, David serves as a speaker and consultant for churches and colleges and is involved in several writing and research projects. David and his wife, Molly, have two daughters and three grandchildren. You can connect with David at https://davidafiensy.com/.

Investigating the anti-hypertensive effects of pumpkin seed oil Marymount University and University of Guilan (Iran), September 29, 2021 In a study, researchers from Iran and the U.S. found that pumpkin seed oil can potentially treat hypertension in postmenopausal women. Their report was published in Complementary Therapies in Clinical Practice. Postmenopausal women are more likely to develop hypertension than men of the same age. In vivo studies reveal that pumpkin seed oil has anti-hypertensive activity. The team investigated the effects of pumpkin seed oil supplementation on vascular function and heart rate variability in postmenopausal women with elevated blood pressure. Participants were assigned to take either a pumpkin seed oil supplement or a placebo for the six-week study. Those in the experimental group took 3 grams of pumpkin seed oil every day. Brachial and central blood pressure, wave reflection (augmentation index, AIx), arterial stiffness (SI) and various HRV parameters were measured at baseline and at the end of the study. Those who took pumpkin seed oil had significantly lower AIx, brachial and systolic blood pressure after treatment. SI and HRV parameters remained unchanged for the treatment group and the placebo group at the end of the study. In sum, taking pumpkin seed oil may improve arterial hemodynamics in postmenopausal women.     Health benefits of evening classes revealed   Oxford University, September 20, 2021    Those with a taste for adult education classes have long known it, but now Oxford University scientists have confirmed that taking part in the weekly sessions can boost wellbeing – regardless of the subject studied.   In partnership with the Workers' Educational Association (WEA), the largest voluntary sector provider of adult education in England and Scotland, a team from Oxford's department of experimental psychology studied attendees at seven separate day-time adult education classes. Their findings are published in a series of papers.   Each class took place over seven months and included a break in the middle. Attendees completed questionnaires before and after their class three times over the seven months: at the beginning of their courses, after 3 months, and at the end of the seven months. Participants were involved in one of three activities: singing, crafts or creative writing.   Overall, attendees at all seven classes had improved mental and physical health and reported more satisfaction with their lives at the end of their courses.   Dr Eiluned Pearce led the research. She said: 'The students reported benefits including increased self-confidence, a greater feeling of control over their lives and more willingness to take on new challenges. Some said the classes made them more motivated to be more active, despite the classes not specifically involving physical activity.   'Participants also said that the classes broadened their networks of friends and gave them an increased sense of belonging. We also found that the more someone felt part of their group, the more their health and wellbeing improved.' An intriguing finding was in the singing and creative writing classes. Building on the results of an earlier paper from the same study, which found that people in singing classes felt closer to their group more quickly than those in the other classes, the team looked at how relationships formed between individuals in the classes.   Each person was asked to name those other people in the class whose name they could remember, whether or not they felt connected to each person they named, and whether they had talked to that person during class.   Dr Pearce said: 'The results showed that those in the singing and creative writing groups built up relationships with other individuals more quickly than the crafters, and singers felt more connected to the class as a whole more quickly than both the other groups. 'While this confirms our earlier finding that singing has an 'ice-breaker effect' compared to other activities, it shows that other activities may enable people to increase their social networks just as much, even if it takes them longer to feel connected to their group as a whole.'   Co-author Dr Jacques Launay adds: 'While much of our previous work has demonstrated the importance of music, it is likely that the most socially bonding activities are always those that are personally chosen and enjoyed. This research adds to growing support for the relevance of creative activities in creating happy communities and improving health and well-being, with consequent benefits for public services and society.'   Dr Pádraig Mac Carron, Dr Anna Machin and Professor Robin Dunbar were also involved in the research.   Howard Croft, WEA Regional Education Manager, said: 'The findings reiterate the feedback that we have had from our students over the years: learning is a fantastic way to boost your self-esteem and confidence. Also of note, is its therapeutic effect. For many students, creative courses are a means of finding a new outlet for expressing their feelings. This can be of immense help during times of personal difficulty or emotional upheaval, such as divorce or bereavement. Simply going to a course can offer much-needed respite.   'For others, learning can be an opportunity to reignite a former passion. This could be anything from a subject which you enjoyed at school to an area which you are interested in. Whatever your reason, there are so many benefits to be gained by signing up to a course.'       Want to live forever? Theoretically, you could, study says Swiss Federal Institute of Technology, September 29, 2021 Humans can probably live to at least 130, and possibly well beyond, though the chances of reaching such super old age remain vanishingly small, according to new research. The outer limit of the human lifespan has long been hotly debated, with recent studies making the case we could live up to 150 years, or arguing that there is no maximum theoretical age for humans. The new research, published Wednesday in the Royal Society Open Science journal, wades into the debate by analyzing new data on supercentenarians—people aged 110 or more—and semi-supercentenarians, aged 105 or more. While the risk of death generally increases throughout our lifetime, the researchers' analysis shows that risk eventually plateaus and remains constant at approximately 50-50. "Beyond age 110 one can think of living another year as being almost like flipping a fair coin," said Anthony Davison, a professor of statistics at the Swiss Federal Institute of Technology in Lausanne (EPFL), who led the research. "If it comes up heads, then you live to your next birthday, and if not, then you will die at some point within the next year," he told AFP. Based on the data available so far, it seems likely that humans can live until at least 130, but extrapolating from the findings "would imply that there is no limit to the human lifespan," the research concludes. The conclusions match similar statistical analyses done on datasets of the very elderly. "But this study strengthens those conclusions and makes them more precise because more data are now available," Davison said. The first dataset the team studied is newly released material from the International Database on Longevity, which covers more than 1,100 supercentenarians from 13 countries. The second is from Italy on every person who was at least 105 between January 2009 and December 2015. 'One in a million' The work involves extrapolating from existing data, but Davison said that was a logical approach. "Any study of extreme old age, whether statistical or biological, will involve extrapolation," he said. "We were able to show that if a limit below 130 years exists, we should have been able to detect it by now using the data now available," he added. Still, just because humans can theoretically reach 130 or beyond, doesn't mean we're likely to see it anytime soon. For a start, the analysis is based on people who have already achieved the relatively rare feat of making it to well over 100. And even at age 110, your chances of making it to 130 are "about one in a million... not impossible but very unlikely," said Davison. He thinks we could see people reaching 130 within the century, as more people make it to supercentenarian status, increasing the chances of one becoming that one in a million. "But in the absence of major medical and social advances, ages much over this are highly unlikely ever to be observed," he added. For now, the oldest person on record is Frenchwoman Jeanne Calment, who died in 1997 at the confirmed age of 122. Her true age was the subject of some controversy, with claims of a possible fraud, but in 2019 several experts said a review of the evidence confirmed her age. Other pretenders to the throne of oldest person ever have a long way to go. The oldest verified living person in the world is Japan's Kane Tanaka, a comparatively youthful 118.     Psychological treatment shown to yield strong, lasting pain relief, alter brain networks University of Colorado, September 29, 2021 Rethinking what causes pain and how great of a threat it is can provide chronic pain patients with lasting relief and alter brain networks associated with pain processing, according to new University of Colorado Boulder-led research. The study, published Sept. 29 in JAMA Psychiatry, found that two-thirds of chronic back pain patients who underwent a four-week psychological treatment called Pain Reprocessing Therapy (PRT) were pain-free or nearly pain-free post-treatment. And most maintained relief for one year. The findings provide some of the strongest evidence yet that a psychological treatmentcan provide potent and durable relief for chronic pain, which afflicts one in five Americans. "For a long time we have thought that chronic pain is due primarily to problems in the body, and most treatments to date have targeted that," said lead author Yoni Ashar, who conducted the study while earning his Ph.D. in the Department of Psychology and Neuroscience at CU Boulder. "This treatment is based on the premise that the brain can generate pain in the absence of injury or after an injury has healed, and that people can unlearn that pain. Our study shows it works." Misfiring neural pathways Approximately 85% of people with chronic back pain have what is known as "primary pain," meaning tests are unable to identify a clear bodily source, such as tissue damage. Misfiring neural pathways are at least partially to blame: Different brain regions—including those associated with reward and fear—activate more during episodes of chronic pain than acute pain, studies show. And among chronic pain patients, certain neural networks are sensitized to overreact to even mild stimuli. If pain is a warning signal that something is wrong with the body, primary chronic pain, Ashar said, is "like a false alarm stuck in the 'on' position." PRT seeks to turn off the alarm. "The idea is that by thinking about the pain as safe rather than threatening, patients can alter the brain networks reinforcing the pain, and neutralize it," said Ashar, now a postdoctoral researcher at Weill Cornell Medicine.or the randomized controlled trial, Ashar and senior author Tor Wager, now the Diana L. Taylor Distinguished Professor in Neuroscience at Dartmouth College, recruited 151 men and women who had back pain for at least six months at an intensity of at least four on a scale of zero to 10. Those in the treatment group completed an assessment followed by eight one-hour sessions of PRT, a technique developed by Los Angeles-based pain psychologist Alan Gordon. The goal: To educate the patient about the role of the brain in generating chronic pain; to help them reappraise their pain as they engage in movements they'd been afraid to do; and to help them address emotions that may exacerbate their pain.  Pain is not 'all in your head' "This isn't suggesting that your pain is not real or that it's 'all in your head'," stressed Wager, noting that changes to neural pathways in the brain can linger long after an injury is gone, reinforced by such associations. "What it means is that if the causes are in the brain, the solutions may be there, too." Before and after treatment, participants also underwent functional magnetic resonance imaging (fMRI) scans to measure how their brains reacted to a mild pain stimulus. After treatment, 66% of patients in the treatment group were pain-free or nearly pain-free compared to 20% of the placebo group and 10% of the no-treatment group. "The magnitude and durability of pain reductions we saw are very rarely observed in chronic pain treatment trials," Ashar said, noting that opioids have yielded only moderate and short-term relief in many trials. And when people in the PRT group were exposed to pain in the scanner post-treatment, brain regions associated with pain processing—including the anterior insula and anterior midcingulate —had quieted significantly. The authors stress that the treatment is not intended for "secondary pain"—that rooted in acute injury or disease. The study focused specifically on PRT for chronic back pain, so future, larger studies are needed to determine if it would yeild similar results for other types of chronic pain.  Meanwhile, other similar brain-centered techniques are already ememrging among physical therapists and other clinicians who treat pain. "This study suggests a fundamentally new way to think about both the causes of chronic back pain for many people and the tools that are available to treat that pain," said co-author Sona Dimidjian, professor of psychology and neuroscience and director of the Renee Crown Wellness Institute at CU Boulder. " It provides a potentially powerful option for people who want to live free or nearly free of pain."     Citicoline (CDP-choline) and Memory Function in Healthy Older Adults: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial  Kyowa Hakko Bio (Japan), September 2021 Supplementation of citicoline (CDP-choline), a naturally occurring mononucleotide, has shown beneficial effects on memory function and behavior in populations with a wide range of impairments. However, few studies have investigated its effect in healthy older populations. Objective The objective of this study was to investigate the effects of citicoline, on memory in healthy elderly populations with age-associated memory impairment (AAMI). Methods A total of 100 healthy men and women aged between 50 and 85 y with AAMI participated in this randomized, double-blind, placebo-controlled trial. Participants were randomized to receive placebo (n = 51) or citicoline (n = 49; 500 mg/d) for 12 wk. Memory function was assessed at baseline and end of the intervention (12 wk) using computerized tests (Cambridge Brain Sciences, Ontario, Canada). Safety measurements included adverse events query, body weight, blood pressure, and hematology and metabolic panel. Intent-to-treat analysis was conducted using ANCOVA for the primary and secondary outcome variables with Bonferroni correction for multiple comparisons. Results A total of 99 out of 100 participants completed the study in its entirety. After the 12-wk intervention, participants supplemented with citicoline showed significantly greater improvements in secondary outcomes of episodic memory (assessed by the Paired Associate test), compared with those on placebo (mean: 0.15 vs. 0.06, respectively, P = 0.0025). Composite memory (secondary outcome), calculated using the scores of 4 memory tests, also significantly improved to a greater extent following citicoline supplementation (mean: 3.78) compared with placebo (mean: 0.72, P = 0.0052). Conclusions Dietary supplementation of citicoline for 12 wk improved overall memory performance, especially episodic memory, in healthy older males and females with AAMI. The findings suggest that regular consumption of citicoline may be safe and potentially beneficial against memory loss due to aging.      Sleep may strengthen long-term memories in the immune system   University of Tuebingen (Germany) September 29, 2021   More than a century ago, scientists demonstrated that sleep supports the retention of memories of facts and events. Later studies have shown that slow-wave sleep, often referred to as deep sleep, is important for transforming fragile, recently formed memories into stable, long-term memories. Now, in an Opinion article published  in Trends in Neurosciences, part of a special issue on Neuroimmunology, researchers propose that deep sleep may also strengthen immunological memories of previously encountered pathogens.   "While it has been known for a long time that sleep supports long-term memoryformation in the psychological domain, the idea that long-term memory formation is a function of sleep effective in all organismic systems is in our view entirely new," says senior author Jan Born of the University of Tuebingen. "We consider our approach toward a unifying concept of biological long-term memory formation, in which sleep plays a critical role, a new development in sleep research and memory research."   The immune system "remembers" an encounter with a bacteria or virus by collecting fragments from the bug to create memory T cells, which last for months or years and help the body recognize a previous infection and quickly respond. These memory T cells appear to abstract "gist information" about the pathogens, as only T cells that store information about the tiniest fragments ever elicit a response. The selection of gist information allows memory T cells to detect new pathogens that are similar, but not identical, to previously encountered bacteria or viruses.   Studies in humans have shown that long-term increases in memory T cells are associated with deep slow-wave sleep on the nights after vaccination. Taken together, the findings support the view that slow-wave sleep contributes to the formation of long-term memories of abstract, generalized information, which leads to adaptive behavioral and immunological responses. The obvious implication is that sleep deprivation could put your body at risk.   "If we didn't sleep, then the immune system might focus on the wrong parts of the pathogen," Born says. "For example, many viruses can easily mutate some parts of their proteins to escape from immune responses. If too few antigen-recognizing cells [the cells that present the fragments to T cells] are available, then they might all be needed to fight off the pathogen. In addition to this, there is evidence that the hormones released during sleep benefit the crosstalk between antigen-presenting and antigen-recognizing cells, and some of these important hormones could be lacking without sleep."   Born says that future research should examine what information is selected during sleep for storage in long-term memory, and how this selection is achieved. In the end, this research could have important clinical implications.   "In order to design effective vaccines against HIV, malaria, and tuberculosis, which are based on immunological memory, the correct memory model must be available," Born says. "It is our hope that by comparing the concepts of neuronal and immunological memory, a model of immunological memory can be developed which integrates the available experimental data and serves as a helpful basis for vaccine development."         Standardized astragalus extract for attenuation of the immunosuppression induced by strenuous physical exercise: randomized controlled trial University of Physical Sciences (Poland), September 3, 2021 This paper aimed to verify how a supplementation of rower's diet with Astragalus Membranaceus Root (AMR) modulated their immune system response to maximal physical exertion. Methods The double-blind study included 18 members of the Polish Rowing Team assigned to the supplemented group (n = 10), and the placebo group (n = 8). The participants performed a 2000 m test on a rowing ergometer at the beginning and at the end of the six-week of intensive training camp during which the supplemented group received 500 mg of AMR. Blood samples were obtained prior to, 1 min after completing, and 24 h after the exertion test. The levels of interleukin 2 (IL2), interleukin 4 (IL4), interleukin 10 (IL10), interferon ɤ (IFN-ɣ), and lactic acid were determined. Subpopulations of T regulatory lymphocytes [CD4+/CD25+/CD127−] (Treg), cytotoxic lymphocytes [CD8+/TCRαβ+] (CTL), natural killer cells [CD3−/CD16+/CD56+] (NK), and TCRδγ-positive cells (Tδγ) were determined with flow cytometry. Results After the camp, the initial NK and Treg levels sustained at the baseline, while Tδγ counts increased relative to the levels in the placebo group. In the supplemented subgroup, a decrease in IL2 level in reaction to maximal exertion clearly deepened while the change in IL-2/IL-10 level induced by the recovery after this exertion clearly increased, relative to the changes in the placebo group. Conclusions AMR restored the immunological balance in strenuously trained athletes through a stabilization of NK and Treg cells with a positive trend in Tδγ towards Th1 response during restitution by cytokine IL2 modulation.

Nachhaltigkeit wird von vielen Organisationen für sich beansprucht. Wie jedoch sieht diese aus? Daniel Bearzatto beschäftigt sich mit dem Thema professionell. In diesem Interview stellt er sich den Fragen von Niels Brabandt. Ihr Gast: Daniel Bearzatto / GF der Agentur für Klimaschutz Tübingen Ihr Gastgeber: Niels Brabandt / NB@NB-Networks.com  

What does portfolio management do in an external service AIFM? Is portfolio management important in an external service AIFM? In an external service AIFM, asset management is usually outsourced to the initiator of the alternative investment fund (AIF). Therefore, the question arises, what does the portfolio management still do and does it have an important function for the AIF? How well does the portfolio management of the external service AIFM know the assets of the AIF? Questions about questions. Portfolio management has an important function, not only in the case of an external service AIFM, but also in general. It is the decision-making function for investment and de-investment decisions in the AIFs. It reviews the current key figures as well as the forecasts and liquidity planning, and it is the interface where the information from the asset manager, the accounting department and the fund's risk management comes together, is reviewed and evaluated. The valuation of assets is another important function. Portfolio Management takes care of selecting suitable valuers for the assets of the AIFs, reports them to the German Federal Financial Supervisory Authority (Bafin) and monitors the correctness of the valuations. The valuations, in turn, are important for determining the value per share, which is calculated by the portfolio management. This means that every investor knows how much his investment is worth. More: https://www.linkedin.com/pulse/what-does-portfolio-management-do-external-service-aifm-zoe-peffer/ The XOLARIS Group will continue to expand its focus as an international AIFM service for real assets. With our locations in Germany, Liechtenstein, France, Hong Kong and Singapore, we are already able to offer our customers individual structuring solutions. True to our motto “Made with Passion”, we take the time to understand the needs of our customers and implement them in individual structuring solutions. Thanks to our integrated approach from structuring to liquidation, we can also take into account all of our customers' wishes in administration and fund accounting. Author Bio: Petra Hamacher-Weiss joined the XOLARIS Group in October 2020 to support the growth strategy and international expansion of the group. She worked in real estate and corporate law since more than 10 years and gained her experience not only from law offices and enterprises but also from working for public authorities. For several years she worked in the management of an international asset management company for closed end AIFs in Germany. Her main focusses there were the legal department and investor relations, especially with French investors and sales partners. She successfully passed her law exam and she's holding a diploma in law from the Eberhard-Karls-University in Tuebingen. ______ www.xol-group.com | XOLARIS AG | Austrasse 15 9490 Vaduz Tel. +423 265 056 0 | Fax +423 265 056 9 | Mail: info@xol-group.com Press/ Podcast Contact: Zoe Peffer | +49 75301 584 880 | marketing@xol-group.com Get inspired for our event reminder emails: http://eepurl.com/hfGLXL XOLARIS Webinar Series LinkedIn Group https://www.linkedin.com/groups/12512062/ Follow us on LinkedIn: www.linkedin.com/company/xolarisgroup, Twitter: https://twitter.com/XolarisG for news and updates or send a message to @xolarisgroup or by e-mail to info@xol-group.com for questions or support.

This event was a discussion around Marc Owen Jones' latest book Political Repression in Bahrain. Exploring Bahrain's modern history through the lens of repression, this concise and accessible account spans the twentieth and twenty-first centuries, looking at all forms of political repression from legal, statecraft, police brutality and informational controls. Considering several episodes of contention in Bahrain, from tribal resistance to the British reforms of the 1920s, the rise of the Higher Executive Committee in the 1950s, the leftist agitation of the 1970s, the 1990s Intifada and the 2011 Uprising, Marc Owen Jones offers never before seen insights into the British role in Bahrain, as well as the activities of the Al Khalifa Ruling Family. From the plundering of Bahrain's resources, to new information about the torture and murder of Bahrain civilians, this study reveals new facts about Bahrain's troubled political history. Using freedom of information requests, historical documents, interviews, and data from social media, this is a rich and original interdisciplinary history of Bahrain over one hundred years. Marc Owen Jones is Assistant Professor in Middle East Studies and Digital Humanities at Hamad bin Khalifa University, Doha. Prior to this, he was a Lecturer in Gulf History at Exeter University, where he remains an Honorary Research Fellow. Before that, Jones won a Teach at Tuebingen award, and wrote and delivered an MA module in Gulf Politics at Tuebingen University’s Institute for Political Science. He recently completed his PhD (funded by the AHRC/ESRC) in 2016 at Durham University, where he wrote an interdisciplinary thesis on the history of political repression in Bahrain. The thesis won the 2016 dissertation prize from the Association for Gulf and Arabian Peninsula Studies. Driven by issues of social justice and a specific area interest in the Gulf, his research spans a number of topics, from historical revisions, postcolonialism, de-democratization and revolutionary cultural production, to policing, digital authoritarianism and human rights. At the moment, Jones is working a number of topics, including propaganda and Twitter bots, mapping sectarian hate speech, and archival work related to Bahrain and land appropriation.

In this episode, Ben is joined by Dr. Dominik Nischwitz - a dentist and naturopath from Germany, who is a pioneer and leader in the field of biological dentistry and ceramic implants. Dr. Dome - as he is also known - is on a mission to educate and start the conversation on how your oral health impacts your entire body and overall wellbeing. This conversation is filled with incredible information on why teeth are considered organs, what cavities are and how to avoid getting them, implantology with bio-identical materials vs. metals, the process of mercury removal and toxicity, how your mouth microbiome affects your gut microbiome and so much more. Dr. Dominik Nischwitz is the President of the International Society of Metal-free Implantology (ISMI) and lectures word-wide on his holistic approach of odontology. Alongside his father, he runs the Centre for Biological Dentistry and Implantology in Tuebingen, Germany. Pick up Dr. Dominik's book to learn more: It's All In Your Mouth: Biological Dentistry and the Surprising Impact of Oral Health on Whole Body Wellness. Follow Dr. Dome on IG @drdome1 for lots of educational content.  If you find this conversation valuable, please share it with someone you love so they can benefit from this information. If you enjoyed today's episode, please leave us a review on ApplePodcasts to support us. To get in touch with us, leave us a comment on Youtube or Instagram.    Sponsor: Thank you to our sponsor BLUBlox - get 15% off with the code MUSCLE. BLUBlox make stylish glasses with specialised BluLite lens filters, which reduce the harmful high energy artificial blue light emitted by digital devices across the entire blue light spectrum. This can help reduce eye strain and sleep disorders. They have day-time and night-time versions and offer free world-wide shipping. Check out BLUBlox and use code MUSCLE to get 15% off.   ⏱Timestamps [00:33] – Today’s guest Dr. Dominik Nischwitz [1:08] – Our sponsor is BLUBlox – use code MUSCLE for 15% off [3:00] – The problem with traditional dentistry [4:10] – Leaky gums and your oral microbiome [5:46] – Dental restorations and their impact on your system [6:25] – Amalgam fillings and mercury toxicity [7:57] – What not to do with your amalgam fillings [8:58] – What mercury does in your teeth and your body [10:00] – Cellphones and mercury fillings [10:35] – Alternative filling materials [11:43] – The process of removing amalgam fillings [13:57] – Root canals = dead teeth [14:18] – Your teeth are connected to your brain [15:54] – The reason for chronic inflammation in your body [16:58] – Can teeth re-grow? [19:25] – The cause of tooth decay [20:35] – Findings of Weston Price [21:58] – Wisdom teeth and braces [22:30] – Dr. Dominik’s mission [23:30] – How to help your kids avoid the same problems [27:28] – Teeth are the mirror for your health [28:19] – Meridian chart of teeth-organ connection [29:15] – Breast cancer and root canals [30:30] – Cavitations [34:15] – Process of becoming a patient at Dr. Nischwitz clinic [35:35] – Education on this new form of dentistry [37:21] – Gum disease [39:17] – Flossing [40:51] – How your teeth can affect your ability to contract muscle [43:30] – Dr. Dome’s bone healing protocol [45:30] – Nutritional advice on bone healing [48:20] – Lasting impact and lifestyle changes [50:21] – How your bite impacts your posture [53:03] – Dr. Dome’s book – and contact information [54:00] – Education for dentists [55:20] – Dr. Dome’s mission [56:10] – Biological dentistry in the US

This Month in German Startups - Summer 2020 Wrap-UpWelcome to this month in German Startups by Startuprad.io - in a transatlantic news recording with Chris in New York City. Today we are wrapping up summer 2020 for you. This is going to take a bit longer than normal, so grab a coffee and relax on the couch.  You can now join us on the entrepreneur network DueDash: https://buff.ly/2R90PYp with 5 Euros a month you support our work! Thank you! EnablerThis recording was made possible by (Hessen Trade and Invest). Learn more about our enabler here: https://www.invest-in-hessen.com/   Find all options to subscribe here: 

This Month in German Startups - Summer 2020 Wrap-UpWelcome to this month in German Startups by Startuprad.io - in a transatlantic news recording with Chris in New York City. Today we are wrapping up summer 2020 for you. This is going to take a bit longer than normal, so grab a coffee and relax on the couch.  You can now join us on the entrepreneur network DueDash: https://buff.ly/2R90PYp with 5 Euros a month you support our work! Thank you! EnablerThis recording was made possible by (Hessen Trade and Invest). Learn more about our enabler here: https://www.invest-in-hessen.com/   Find all options to subscribe here: 

Owen ist seit Corona mit seinem Start-Up aus dem Silicon Valley nach Tübingen gezogen. Mit seinem Start-Up lüftet er das letzte Geheimnis des menschlichen Körpers - er digitalisiert das Gehirn.***Folge 5 mit Owen Phillips findest Du hier (Apple | Spotify). Meine aktuelle WiWo Kolumne zum Thema: 'Macht uns Smart Health alle zu Hypochondern?' findest du hier. ***Diese Folge wird unterstützt von BRAINEFFECT. 20% Rabatt auf deinen Einkauf von Performance-Food mit dem Gutschein-Code OPTIMISTEN20 auf www.brain-effect.com.***Alle Infos auf www.digitaleoptimisten.de***Ich habe  das Glück in diesem Podcast mit so vielen wahnsinnig smarten Gründern aus unterschiedlichsten Branchen zu sprechen: Smart Home, Mobility, Human Resources, Smart Health, Sportwetten und viele mehr. Was mich an all den Gesprächen so interessiert ist dass die Gründer noch ganz am Ende stehen, wo der Nebel noch ganz dicht über der Zukunft liegt. Deshalb mache ich immer wieder Check-In Folgen, in denen ich mit Gründern spreche, die schon mal zu Gast waren. Und sich dieser Nebel ein bisschen mehr verzogen hat. Einige haben ihr Geschäftsmodell schon total umgekrempelt, bei anderen läuft die nächste Finanzierungsrunde und wieder andere habe aufgegeben. Heute spreche ich wieder mit Owen Phillips, der in Folge 5 zu Gast war. Owen will mit seinem Start-Up BrainKey das letzte große Geheimnis des menschlichen Körpers lüften: er möchte das Gehirn jedes einzelnen digitalisieren, analysieren und letztlich Krankheiten wie Alzheimer einfacher erkenn- und behandelbar machen. Hier ein kurzes Ausschnitt aus der Folge:Dieser Check-In ist deshalb so interessant für mich gewesen, weil Covid-19 natürlich eine unglaubliche Auswirkung auf Smart Health Start-Ups hat. Owen beschreibt, wie er den Wind für sein Geschäftsmodell nutzen will, aber auch wie leer San Francisco geworden ist als direkte Folge der Pandemie. Und.. gute Nachrichten für den Standort Deutschland, denn Owen hat sich entschieden aus Tübingen aus zu arbeiten. Mehr Gedanken von mir zu Smart Health findest du auch in meiner aktuellen Wirtschaftswoche Kolumne, in der mich frage, ob wir mit Smart Health alle zu Hypochondern werden. Den Link findest Du in den Shownotes unter dieser Folge.

Using a mixture of genres, Kent Gramm captures the voices of those past and present in his book, Gettysburg: The Living and the Dead(Southern Illinois University Press, 2019) Alongside stunning photographs by Chris Heisey, Gramm shares the experiences of the people at Gettysburg—both those historical figures who took part in the battle in some meaningful way and those of us today who return to the battlefield to try and make sense of such a tragic and mournful part of our history. Gramm’s writing style is eloquent and thought-provoking. By listening to the people who were at Gettysburg, he brings them back to life in a way that reveals the truth of the human experience and elicits empathy from his readers. Gettysburg: The Living and the Dead is emotionally stirring and absolutely essential toward helping us understand and heal from this tragic, watershed event in American history. Kent Gramm is an adjunct professor of English and Civil War Era Studies at Gettysburg College in Gettysburg, Pennsylvania. A Wisconsin native, Gramm has also taught at colleges in Germany, Illinois, and Indiana. He holds a PhD in Creative Writing and American Literature from the University of Wisconsin, Milwaukee, and studied theology at Princeton Theological Seminary at the University of Tuebingen, Germany. He has written books, plays, novels, and poetry about Abraham Lincoln, Gettysburg, and the American Civil War. His book, November: Lincoln's Elegy at Gettysburg, was nominated for a Pulitzer Prize, and the graduate writing program at LSU awards an annual Kent Gramm Prize in Creative Nonfiction. Finally, he is a lifelong student of the Civil War. Colin Mustful is the author of four historical novels about Minnesota’s settlement and Native history. He holds an MA in history and a MFA in creative writing. He is the founder and editor of a small independent press called History Through Fiction. You can learn more about Colin and his work at colinmustful.com. Learn more about your ad choices. Visit megaphone.fm/adchoices

Using a mixture of genres, Kent Gramm captures the voices of those past and present in his book, Gettysburg: The Living and the Dead(Southern Illinois University Press, 2019) Alongside stunning photographs by Chris Heisey, Gramm shares the experiences of the people at Gettysburg—both those historical figures who took part in the battle in some meaningful way and those of us today who return to the battlefield to try and make sense of such a tragic and mournful part of our history. Gramm’s writing style is eloquent and thought-provoking. By listening to the people who were at Gettysburg, he brings them back to life in a way that reveals the truth of the human experience and elicits empathy from his readers. Gettysburg: The Living and the Dead is emotionally stirring and absolutely essential toward helping us understand and heal from this tragic, watershed event in American history. Kent Gramm is an adjunct professor of English and Civil War Era Studies at Gettysburg College in Gettysburg, Pennsylvania. A Wisconsin native, Gramm has also taught at colleges in Germany, Illinois, and Indiana. He holds a PhD in Creative Writing and American Literature from the University of Wisconsin, Milwaukee, and studied theology at Princeton Theological Seminary at the University of Tuebingen, Germany. He has written books, plays, novels, and poetry about Abraham Lincoln, Gettysburg, and the American Civil War. His book, November: Lincoln's Elegy at Gettysburg, was nominated for a Pulitzer Prize, and the graduate writing program at LSU awards an annual Kent Gramm Prize in Creative Nonfiction. Finally, he is a lifelong student of the Civil War. Colin Mustful is the author of four historical novels about Minnesota’s settlement and Native history. He holds an MA in history and a MFA in creative writing. He is the founder and editor of a small independent press called History Through Fiction. You can learn more about Colin and his work at colinmustful.com. Learn more about your ad choices. Visit megaphone.fm/adchoices

Using a mixture of genres, Kent Gramm captures the voices of those past and present in his book, Gettysburg: The Living and the Dead(Southern Illinois University Press, 2019) Alongside stunning photographs by Chris Heisey, Gramm shares the experiences of the people at Gettysburg—both those historical figures who took part in the battle in some meaningful way and those of us today who return to the battlefield to try and make sense of such a tragic and mournful part of our history. Gramm’s writing style is eloquent and thought-provoking. By listening to the people who were at Gettysburg, he brings them back to life in a way that reveals the truth of the human experience and elicits empathy from his readers. Gettysburg: The Living and the Dead is emotionally stirring and absolutely essential toward helping us understand and heal from this tragic, watershed event in American history. Kent Gramm is an adjunct professor of English and Civil War Era Studies at Gettysburg College in Gettysburg, Pennsylvania. A Wisconsin native, Gramm has also taught at colleges in Germany, Illinois, and Indiana. He holds a PhD in Creative Writing and American Literature from the University of Wisconsin, Milwaukee, and studied theology at Princeton Theological Seminary at the University of Tuebingen, Germany. He has written books, plays, novels, and poetry about Abraham Lincoln, Gettysburg, and the American Civil War. His book, November: Lincoln's Elegy at Gettysburg, was nominated for a Pulitzer Prize, and the graduate writing program at LSU awards an annual Kent Gramm Prize in Creative Nonfiction. Finally, he is a lifelong student of the Civil War. Colin Mustful is the author of four historical novels about Minnesota’s settlement and Native history. He holds an MA in history and a MFA in creative writing. He is the founder and editor of a small independent press called History Through Fiction. You can learn more about Colin and his work at colinmustful.com. Learn more about your ad choices. Visit megaphone.fm/adchoices

Using a mixture of genres, Kent Gramm captures the voices of those past and present in his book, Gettysburg: The Living and the Dead(Southern Illinois University Press, 2019) Alongside stunning photographs by Chris Heisey, Gramm shares the experiences of the people at Gettysburg—both those historical figures who took part in the battle in some meaningful way and those of us today who return to the battlefield to try and make sense of such a tragic and mournful part of our history. Gramm’s writing style is eloquent and thought-provoking. By listening to the people who were at Gettysburg, he brings them back to life in a way that reveals the truth of the human experience and elicits empathy from his readers. Gettysburg: The Living and the Dead is emotionally stirring and absolutely essential toward helping us understand and heal from this tragic, watershed event in American history. Kent Gramm is an adjunct professor of English and Civil War Era Studies at Gettysburg College in Gettysburg, Pennsylvania. A Wisconsin native, Gramm has also taught at colleges in Germany, Illinois, and Indiana. He holds a PhD in Creative Writing and American Literature from the University of Wisconsin, Milwaukee, and studied theology at Princeton Theological Seminary at the University of Tuebingen, Germany. He has written books, plays, novels, and poetry about Abraham Lincoln, Gettysburg, and the American Civil War. His book, November: Lincoln's Elegy at Gettysburg, was nominated for a Pulitzer Prize, and the graduate writing program at LSU awards an annual Kent Gramm Prize in Creative Nonfiction. Finally, he is a lifelong student of the Civil War. Colin Mustful is the author of four historical novels about Minnesota’s settlement and Native history. He holds an MA in history and a MFA in creative writing. He is the founder and editor of a small independent press called History Through Fiction. You can learn more about Colin and his work at colinmustful.com. Learn more about your ad choices. Visit megaphone.fm/adchoices

Using a mixture of genres, Kent Gramm captures the voices of those past and present in his book, Gettysburg: The Living and the Dead(Southern Illinois University Press, 2019) Alongside stunning photographs by Chris Heisey, Gramm shares the experiences of the people at Gettysburg—both those historical figures who took part in the battle in some meaningful way and those of us today who return to the battlefield to try and make sense of such a tragic and mournful part of our history. Gramm’s writing style is eloquent and thought-provoking. By listening to the people who were at Gettysburg, he brings them back to life in a way that reveals the truth of the human experience and elicits empathy from his readers. Gettysburg: The Living and the Dead is emotionally stirring and absolutely essential toward helping us understand and heal from this tragic, watershed event in American history. Kent Gramm is an adjunct professor of English and Civil War Era Studies at Gettysburg College in Gettysburg, Pennsylvania. A Wisconsin native, Gramm has also taught at colleges in Germany, Illinois, and Indiana. He holds a PhD in Creative Writing and American Literature from the University of Wisconsin, Milwaukee, and studied theology at Princeton Theological Seminary at the University of Tuebingen, Germany. He has written books, plays, novels, and poetry about Abraham Lincoln, Gettysburg, and the American Civil War. His book, November: Lincoln's Elegy at Gettysburg, was nominated for a Pulitzer Prize, and the graduate writing program at LSU awards an annual Kent Gramm Prize in Creative Nonfiction. Finally, he is a lifelong student of the Civil War. Colin Mustful is the author of four historical novels about Minnesota’s settlement and Native history. He holds an MA in history and a MFA in creative writing. He is the founder and editor of a small independent press called History Through Fiction. You can learn more about Colin and his work at colinmustful.com. Learn more about your ad choices. Visit megaphone.fm/adchoices

Dr Roland Löffler, Director of the Regional Agency for Civic Education in Saxony, eastern Germany, delivered the keynote address to the Cumberland Lodge conference on Difficult Histories & Positive Identities, on Monday 25 February 2019. He spoke for 40 minutes, to an audience of experts and practitioners from diverse educational institutions and civil society, on 'Remembering the Past, Debating the Future: Political Education and the Challenge of Populism'. Roland studied protestant theology at the universities of Tuebingen, Berlin and Cambridge. He received his PhD from the University of Marburg and went on to work as a freelance journalist whilst training to be a pastor in the Protestant Church. He was also a guest professor at the University of Montreal. In 2007, he joined the Herbert Quandt Foundation. He went on to become Chief Executive of the Foundation Westphalia Initiative, before becoming Director of the Regional Agency for Civic Education in Saxony, in 2017. Roland's interests and expertise include migration, intercultural education, civic society, demographic change, and life in rural areas. The focus of his recent work has been on the development of civic engagement and political cultural in East Germany. Roland has advised charities supporting Arab Christians, and he has a keen interest in German-Polish and German-Northern Europe relations.

Ask Win is a podcast where you are a VIP. Win wants to focus and teach people more and Cerebral Palsy. You’re welcome to ask questions about anything that you want. CP questions but mainly life questions on how to deal with CP or not. Win can ask you base questions if you want. Please let us know or there will be no base questions. If you have any questions for Win please email her at askingwkelly@gmail.com. In 2018 let be open and honest on Ask Win. To learn more about Ask Win visit http://askwin.weebly.com. Be sure to FOLLOW this program https://itunes.apple.com/us/podcast/wins-women-of-wisdom/id1060801905. Plan A: Please donate to Ask Win by going to Payment Venmo Win1195 at https://venmo.com/. Plan B: Have you seen Cash App? Try it using my code and we’ll each get $5. TJHHMMQ: https://cash.me/app/TJHHMMQ. Plan C: $60 to $100 for Ask Win: https://www.nolo.com/legal-encyclopedia/form-nonprofit-eight-steps-29484.html. Plan D: Please support this podcast by PayPal at https://www.paypal.me/WCharles, https://www.patreon.com/Askwin, or go to https://www.zellepay.com/how-it-works. Check out Ask Win on Shopio at http://www.shopio.com/?ref=askwin. Google Podcasting App Product Manager #212 - New Media Show: https://www.stitcher.com/podcast/geek-news-central-podcast/the-new-media-show/e/55231838?autoplay=true. Inktale: https://inktale.com. To see Wn’s art and learn more about her go to http://www.blurb.com/b/1656186-art-by-win-k-charles, https://www.redbubble.com/people/wcharles/portfolio, and http://linkedin.com/in/win-c-1a25b984. Please donate to Aspen Country Day School at https://www.aspencountryday.org/page.cfm?p=652. Get cash back for shopping on Ebates! Sign up with Win’s invite link for a $10 bonus when you shop at over 2,000 stores like eBay, Macy’s & Walmart. The link is https://go.ebat.es/imsk/2IHGc9cNtK. Join us on LinkedIn at https://www.linkedin.com/in/authorwincharles/. To follow Win’s new page CP Fashion go to https://www.facebook.com/cpfashion81611/. Academy of Art University Online Open House: https://youtu.be/5UpzLgK46CE. To learn how Win walk and about Ekso go to http://www.bridgingbionics.org/, or email Amanda Boxtel at amanda@bridgingbionics.org. Please donate to the Bridging Bionics Foundation. Please send a check in the mail so 100% goes to Bridging Bionics Foundation. In the Memo section have people write: In honor of Win Charles and Danielle Coulter. Thank you in advance, Win and Danielle. Send to: Bridging Bionics Foundation PO Box 3767 Basalt, CO 81621 Thank you Win On Ask Win today (Tuesday, December 11, 2018), Best-Selling Author, Win C welcomes David Fiensy. After graduating from Duke University with a Ph.D. in New Testament and Second Temple Judaism, David Fiensy taught for seven years at Kentucky Christian University. He then served a two year tenure at the Institut zur Erforschung des Urchristentums in Tuebingen, Germany. Upon returning to the United States, he accepted a church pastorate for six years and then resumed teaching at Kentucky Christian University. He has participated in seven archaeological excavations and surveys and has other wise traveled widely in the Mediterranean area and the Middle East. He is now semi-retired and involved in several writing projects. He and his wife are the parents of two daughters and two granddaughters. He enjoys running, hiking, cycling, and reading mystery novels. To learn more about David email him at dfiensy@gmail.com. To get School of Podcasting Monthly Membership go to https://www.theschoolofpodcasting.com/bundles/school-of-podcasting-monthly-membership?ref=6e6340. To buy Win’s first bio, I, Win, go to https://amzn.to/2mnDtyA. To donate to I, Win go to https://www.paypal.me/askwin. To listen to I, Win on Audible go to https://www.amazon.com/Win-Journey-Disabled-Living-Non-Disabled/dp/B00BL7VZRI/ref=mp_s_a_1_1?ie=UTF8&qid=1533509424&sr=1-1&pi=AC_SX236_SY340_QL65&keywords=I%2CWin%3A+Hope+and+Life%3A+My+Journey+as+a+Disabled+Woman+Living+in+a+Non-Disabled+World&dpPl=1&dpID=51VEVReFh3L&ref=plSrch. To go buy Danielle Coulter’s books go to https://www.amazon.com/kindle-dbs/author?_encoding=UTF8&asin=B00OFIOY3C. To go buy Carla Wynn Hall’s books go to https://www.amazon.com/kindle-dbs/author/ref=dbs_P_W_auth?_encoding=UTF8&author=Carla%20Wynn%20Hall&searchAlias=digital-text&asin=B00HU8SDFO.

Shivdasani lecture Prof. G. C. Tripathi 3 Nov 2016 The lecture would shed light on the Indian phenomenon of monasticism (shrama, shramana) and asceticism (tapas,tapasvin). Buddhist monks are referred to as shramanas, the toilers. The concept of shrama (labour) has a spiritual connotation in the Vedic literature. Monastic way of life, according to me, was not a protest or revolution against the established religious order. Its tradition seems to be as old that of Vedic ritual, although it was formalised and given a well structured form by Mahavira and especially by Buddha. However they were not the inventors of this tradition. Many Rishis and Aranyakas (Vaikhanasas!) lead a life very akin to that of a monk. Tapas etymologically means ‘heat’ and tapasya is ‘accumulation of heat’ where the expression ‘heat’ is understood in the sense of spiritual energy. Performance of austerities is believed to endow a person with extra-ordinary capabilities which could be of many use, besides , of course, spiritual enlightenment. Tapas is usually associated with the concept of a Rsi who can see beyond time and space. We shall deal with these concepts and trace the history of the spread of monasticism in the west from India in short. Prof. Gaya Charan Tripathi was born at Agra (India). He went to school and pursued higher studies at Agra, Pune, and Benares. He has a Masters in Sanskrit (1959) from the University of Agra with a Gold Medal and first position in the University. He received his Ph.D. from the same University in 1962 on Vedic Deities and their subsequent development in the Epics and the Puranas supported by a Fellowship of the Ministry of Education. He is a Fellow of the German Academic Exchange Service (DAAD) for Higher Studies in Germany. He has a Dr.Phil. from the University of Freiburg/Br (1966) in History of Religions, Comparative Indo-European Philology, and Latin (besides Indology) as elective subjects in the grade Summa cum Laude. D.Litt. in Ancient Indian History and Culture from the University of Allahabad on ‘A critical Study of the daily Puja Ceremony of the Jagannatha Temple in Puri’ (published under the title Communication with God). He has taught at the Universities of Aligarh, Udaipur, Freiburg (twice), Tuebingen (twice), Heidelberg, Berlin, Leipzig, Philipps-Universität Marburg, and British Columbia (Vancouver). He is Chief Indologist and Field Director of the Orissa Research Project (1970–5) of the German Research Council (DFG), and has been Principal of the Ganganatha Jha Research Institute, Allahabad, for over twenty years. He was Professor and Head of the Research and Publication wing of the Indira Gandhi National Centre for the Arts, Delhi, and is presently Director of the Bhogilal Leherchand Institute of Indology in New Delhi. He has published 22 books on subjects mostly pertaining to religions and literature of India. His specialisations are: Indian Religions and Philosophy, Vishnuism (especially Pancharatra school), Vedic studies, Sanskrit Literature, Grammar, and Philology, Cult practices of Orissa, and Gaudiya Vishnuism.

Shivdasani lecture Prof. G. C. Tripathi 24 Nov 2016 The paper shall try to trace the close relationship of the Orissan Tantrism and also Vishnuism to Kashmir of the 10th-12th Century. It were most probably the Orissan students learning in the Pathashalas of Kashmir, mentioned (sarcastically) by Kshemendra who brought the philosophy and ritual of Kashmir along with manuscripts from there to Orissa which enriched Orissan Vishnuism overlaid by Tantric practices. The paper would also shed light on the historical aspect of this relationship. Prof. Gaya Charan Tripathi was born at Agra (India). He went to school and pursued higher studies at Agra, Pune, and Benares. He has a Masters in Sanskrit (1959) from the University of Agra with a Gold Medal and first position in the University. He received his Ph.D. from the same University in 1962 on Vedic Deities and their subsequent development in the Epics and the Puranas supported by a Fellowship of the Ministry of Education. He is a Fellow of the German Academic Exchange Service (DAAD) for Higher Studies in Germany. He has a Dr.Phil. from the University of Freiburg/Br (1966) in History of Religions, Comparative Indo-European Philology, and Latin (besides Indology) as elective subjects in the grade Summa cum Laude. D.Litt. in Ancient Indian History and Culture from the University of Allahabad on ‘A critical Study of the daily Puja Ceremony of the Jagannatha Temple in Puri’ (published under the title Communication with God). He has taught at the Universities of Aligarh, Udaipur, Freiburg (twice), Tuebingen (twice), Heidelberg, Berlin, Leipzig, Philipps-Universität Marburg, and British Columbia (Vancouver). He is Chief Indologist and Field Director of the Orissa Research Project (1970–5) of the German Research Council (DFG), and has been Principal of the Ganganatha Jha Research Institute, Allahabad, for over twenty years. He was Professor and Head of the Research and Publication wing of the Indira Gandhi National Centre for the Arts, Delhi, and is presently Director of the Bhogilal Leherchand Institute of Indology in New Delhi. He has published 22 books on subjects mostly pertaining to religions and literature of India. His specialisations are: Indian Religions and Philosophy, Vishnuism (especially Pancharatra school), Vedic studies, Sanskrit Literature, Grammar, and Philology, Cult practices of Orissa, and Gaudiya Vishnuism.

Dr. Carolyn Lam:               Welcome to Circulation on the Run, your weekly podcast summary and backstage pass to the journal and its editors. I'm Dr. Carolyn Lam, associate editor from the National Heart Centre and Duke-National University of Singapore. Our feature discussion today centers on patients with acute stroke due to large vessel occlusion, and asks the question, "Does interhospital transfer prior to thrombectomy relate to delayed treatment and worse outcomes?" Well, stay tuned for more right after these summaries.                                                 Our first original paper this week tells us that cardio protection is alive, and mitochondrial cardiomyocyte calcium-activated potassium channels of the BK type may be a promising target. In this study from first author Dr. Frankenreiter, corresponding author Dr. Lukowski, from University of Tuebingen in Germany, the authors used a combination of transgenic, pharmacologic and electrophysiological approaches to show that mice with a cardiomyocyte-specific knockout of BK channels had larger infarct size after 30 minutes of coronary occlusion, and 120 minutes of reperfusion, and were less protected by ischemic pre- and post-conditioning maneuvers, such as guanylate cyclase stimulators or activators and phosphodiesterase-5 inhibitors.                                                 In a chronic infarct model, mice with cardiomyocyte-specific knockout of BK channels had more fibrosis and lower left ventricular function. Mechanistically, the activation of BK channels in the inner mitochondrial membrane by cyclic GMP and protein kinase G was identified by patch clamping, and resulted in reduced formation of reactive oxygen species and activation of cardioprotective signaling. In summary, deficiency of BK channels in cardiomyocyte mitochondria rendered the heart highly vulnerable to ischemic and reperfusion injury, whereas the beneficial effects of cardioprotective agents known to target the nitric oxide cyclic GMP pathway required these cardiomyocyte BK channels. This thus establishes these cardiomyocyte mitochondrial BK channels as a promising target for limiting acute cardiac damage and adverse long-term events following myocardial infarction.                                                 The next study suggests that integration of maximal myocardial blood flow and coronary flow reserve, termed coronary flow capacity, may be helpful in predicting cardiovascular mortality in patients with stable coronary artery disease. First author Dr. Gupta, corresponding author Dr. Di Carli, and colleagues from Brigham and Women's Hospital, quantify myocardial blood flow and coronary flow reserve in more than 4,000 consecutive patients referred for myocardial perfusion PET scans from 2006 to 2013.                                                 Maximal myocardial blood flow of less than 1.8 mLs per gram per minute, and coronary flow reserve of less than two, were considered impaired. Four patient groups were then identified based on the concordant or discordant impairment of maximal myocardial blood flow, or its coronary flow reserve. The authors found that in patients with known or suspected coronary artery disease, impaired coronary flow reserve with preserved maximal myocardial blood flow identifies patients at an increased risk of cardiovascular mortality, despite a lack of myocardial ischemia. Patients who may be targeted for initiation or intensification of lifestyle preventive therapies for cardiovascular risk reduction. Conversely, preserved coronary flow reserve, even in the absence of impaired myocardial blood flow, identifies patients at low risk, in whom the need for revascularization should be reevaluated.                                                 The next study provides insights into cardiac regeneration, particularly with regards to using resident cardiac progenitor cells expressing the tyrosine kinase receptor c-Kit, which is being tested in clinical trials. In this study from first authors Dr. Chen and Zhu, corresponding authors Dr. van Berlo from University of Minnesota and colleagues, the authors used single-cell sequencing and genetic lineage tracing to show that there was innate heterogeneity within these c-Kit positive cardiac cells, where some have either endothelial or mesenchymal identity. Cardiac pressure overload resulted in a modest increase in c-Kit derived cardiomyocytes, with significant increases in the number of endothelial cells and fibroblasts. On the other hand, doxorubicin-induced acute cardio toxicity did not increase c-Kit derived endothelial cell fates, but instead induced cardiomyocyte differentiation.                                                 Although the overall rate of cardiomyocyte formation from c-Kit positive cells was below clinically-relevant levels, the authors further showed an important role for p53 in the differentiation of c-Kit positive cells to cardiomyocytes. Thus, this paper shows that different pathologic stimuli induced different cell fates in c-Kit positive target cells. These are novel findings that could aid in the development of strategies to preferentially regenerate cardiomyocytes.                                                 Since December 2014, a series of pivotal trials have shown that endovascular thrombectomy was highly effective in acute stroke management, prompting calls for reorganization of stroke systems of care. But how have these trials influenced the frequency of endovascular thrombectomy in clinical practice? Well, the last original paper in this week's journal tells us how. First and corresponding author, Dr. Smith from University of Calgary in Alberta, Canada, and colleagues, used data from the Get With The Guidelines stroke program to determine how the frequency of endovascular thrombectomy has changed in U.S. practice. They analyzed prospectively-collected data from a cohort of more than two million ischemic stroke patients, admitted to more than 2,000 participating hospitals between 2003 and the third quarter of 2016.                                                 The authors found that the use of endovascular thrombectomy for acute ischemic stroke accelerated sharply after the publication of pivotal randomized control trials beginning in December 2014. The endovascular thrombectomy case volume doubled at hospitals providing therapy. In the third quarter of 2016, endovascular thrombectomy was provided to 3.3% of all ischemic stroke patients. This represented 15.1% of all patients who were potentially eligible for endovascular thrombectomy based on stroke duration and severity. In summary, endovascular thrombectomy use is increasing rapidly, however there are still opportunities to treat more patients. Reorganizing stroke systems to route patients to adequately resourced endovascular thrombectomy-capable hospitals might increase treatment of eligible patients, improve outcomes, and reduce disparities.                                                 Coming right up, we will be discussing even more about endovascular thrombectomy in acute stroke management. Just hang on, our feature discussion is coming right up.                                                 Endovascular treatment with mechanical thrombectomy is beneficial for acute stroke patients suffering a large vessel occlusion. And that is in the guidelines, however we also know that treatment efficacy is highly time-dependent. And so, will interhospital transfer to an endovascular-capable center help in cases of acute large vessel stroke? Well, today's feature paper really helps to present novel data to answer that question. And it is from the STRATIS study. I'm so delighted to have with us the first and corresponding author, Dr. Michael Froehler from Vanderbilt University Medical Center, who will tell us about his findings, as well as Dr. Graeme Hankey, associate editor from University of Western Australia, joining us today. Welcome, gentlemen. Dr. Michael Froehler:     Hello Carolyn. Dr. Graeme Hankey:       Thank you Carolyn. Dr. Carolyn Lam:               Thanks for making the time. Mike, tell us about the STRATIS study. What inspired it, what you found. Dr. Michael Froehler:     Well, the STRATIS study was actually a large registry of the use of the Solitaire device for large vessel occlusion. Those results, the primary results, were published separately. But what we did in this study is look at one key aspect of the system of care for stroke delivery, in terms of its effect on time to treatment and patient outcomes.                                                 And so in short, what we found is that patients that are transferred from one hospital to another for mechanical thrombectomy take longer to receive treatment, and do worse in terms of functional outcome, compared to the patients that present directly to that thrombectomy center. Dr. Carolyn Lam:               Wow. Could you put some numbers to that? Dr. Michael Froehler:     Well, so we looked at 984 patients, almost a thousand patients. And what we found was that the time from stroke onset to revascularization, until the time the vessel was actually opened, was 202 minutes on average, for patients that presented directly to the thrombectomy center. Compared to over 311 minutes for patients that were transferred from one hospital to another. So that's a difference, on average, of over 100 minutes. Dr. Carolyn Lam:               And I really was impressed with this other analysis you did. So I was wondering if you could share, where you did a hypothetical bypass modeling. Could you tell us about that? Because I thought that was really practical with a feasible message as well. Dr. Michael Froehler:     I'm excited about that, and I should also share with you that we're working on a more in-depth bypass analysis, to really understand the implications of going to one center directly versus another. But the model that is built in to this publication is really designed to answer one or two questions. And the first is, how much time would we save if we went directly to the thrombectomy-capable center, compared to what actually happened? Meaning the patient was taken to a regional hospital and then subsequently transferred to the thrombectomy-capable center. And this was basically an ideal scenario.                                                 So if they were taken to one hospital and then transferred to another, we simply calculated what the maximum driving time from the starting position to the thrombectomy-capable center would be. And that did rest on the assumption that you actually had to drive past the first hospital. We didn't take any shortcuts in terms of the driving, and probably that small amount of driving time is actually shorter than the number that we found in our calculation.                                                 So the first question was, how much time would we save with that bypass? And the second question was, what kind of impact would that have on IV-tPA? Because, as a lot of us are thinking right now, with strong evidence in support of endovascular therapy for large vessel occlusion, if necessary how should we prioritize getting to endovascular treatment versus the standard therapy that we've known for 20 years, which is IV-tPA? And if you've got a choice, which one is more important?                                                 I don't know the answer to that question, but to try and help lead up to it, we did this hypothetical bypass analysis to look at the impact of bypass, driving directly to the thrombectomy center, the impact of that on the time to delivery of IV-tPA. And so that was really the second question that we asked with this hypothetical bypass analysis. Dr. Carolyn Lam:               Yeah. I love that analysis, because I agree with you, it's a very, very practical question, and it's the way we clinicians think, right? So, tell us, what's the bottom line? Dr. Michael Froehler:     So, the bottom line is, you're gonna save about an hour and a half if you bypass the regional hospital and go directly to the thrombectomy-capable center. On average, you're gonna get to the ultimate treatment center 91 minutes sooner, compared to the transferred group. Contrast that 91-minute time savings with a delay of IV-tPA delivery of 12 minutes. So yes, tPA will be delivered a little bit later, but endovascular therapy will be delivered much sooner.                                                 Now, that solution is probably not going to work everywhere, depending on your geography. So one of the other things we did within the hypothetical bypass analysis was limit that analysis only to patients who were transferred within a 20-mile radius. And that doesn't seem like a long distance, but actually there's a lot of patients in that group, that are still taken to the nearest hospital and then need to be transferred to another hospital that may be less than 20 miles away.                                                 So if we looked at that group of patients, then thrombectomy is still performed an hour and a half earlier, in that analysis it was 94 minutes earlier, but IV-tPA was delayed by only seven minutes. So certainly, there is a large group of patients out there that are perhaps being taken to hospitals that are not necessary, it's not a necessary stop. Dr. Carolyn Lam:               Wow, Mike, this is really amazing results, it's starting to make me think of the old days of acute myocardial infarction treatment, when we were thinking of intravenous thrombolytics, comparison to primary PCI, an analogy and comparison that was also mentioned in the accompanying editorial that you invited. Graeme, would you like to share some of your thoughts on the implication of all this? Dr. Graeme Hankey:       Just to take a step back, of course this begins with a stroke occurring out in the field. And unlike acute coronary syndromes, where chest pain is the major symptom, there are many symptoms of stroke. And the first problem is trying to identify the patient who has actually had a stroke, and in particular, one of the 15% or so who's had a large vessel occlusion, who's amenable to large vessel mechanical thrombectomy. So in the field we have an issue with clinical triage, and trying to work out who's the one in six who really need endovascular therapy, and who are the five in six who perhaps don't.                                                 And we're trying to develop clinical triage scales like the RACE scale to work out in the ambulance where someone should go. But we still haven't nailed that yet. Then you have scales that are very sensitive but not very specific, and have a high sort of false-positive rate. So then the question at the ambulance is, where does it go, to the hospital, the primary stroke center nearby, and give the patient the earliest opportunity to get tPA?                                                 And that's the potential benefit of early transfer to a primary center, but tPA is not very effective in dissolving these big clots in large arteries. And so, of course the trials have shown a substantial benefit of endovascular therapy to remove the clots via thrombectomy. But those resources, they're only really limited to comprehensive stroke units, and that's what this paper was about. So the trade-off is early transfer to the primary center so you can get some tPA, versus delaying, as Michael has shown, by 1 1/2 to two hours on average, to get to a comprehensive center that can access the expertise of endovascular thrombectomy experts.                                                 And this paper is really taking us forward in emphasizing again that time is brain, and we really don't want to delay. Perhaps there's a small trade-off in driving a little bit further, another 20 miles at the most perhaps, to get to a comprehensive center directly. And there may be some who are not shown to have a large vessel occlusion at that comprehensive stroke center, but the overall benefit is probably offset, the few who might miss out on tPA. And so this is a really important study, the largest registry of large vessel occlusion patients to observe and compare the outcomes after adjusting for all the different factors. And give us some clues, that perhaps we really need to be trying to focus on building our resources in comprehensive stroke centers, and also being able to more accurately identify those who are likely to benefit and go directly there. Dr. Michael Froehler:     I agree with everything Graeme said, and I would just amplify one thing that he said, that it does depend on distance, and those distances in turn depend on your own geography. We did an analysis of all our transferred patients and then limited it to those that were within a 20-mile radius. For Graeme in Western Australia, you know Graeme's mailbox is probably 20 miles away. And so there are huge distances in Western Australia to account for. And it may not be possible. Dr. Carolyn Lam:               Contrast that to me in Singapore. I think if I drive any bit more, and I'll be driving out of my country already. Dr. Michael Froehler:     I think that you make a great point though, Carolyn, that the solution that works for metro Singapore is not what's going to work for rural Western Australia. And we've seen this in New York City, for example. My colleagues at Mount Sinai are looking at different ways to deliver care across metro New York, which obviously is very different compared to myself in Nashville, Tennessee. So the right solution is not gonna be the same solution for everyone. Dr. Graeme Hankey:       And that's right Carolyn, because in rural places like out in Western Australia, we are learning now that another important message is to try and help upscale and reorganize our primary stroke centers, or just our medical centers out in the rural and remote areas. Because as Mike's paper shows, the delays once someone comes to a primary stroke center or a rural center, is about 30 minutes for diagnosis, about 30 minutes to arrange the transport, and about 30 minutes to actually do the transport.                                                 So we need to once trying to develop comprehensive stroke units, also build up those peripheral hub and spoke centers to be more slick with their diagnosis, arrangement of transport, and transport times. And one of the important things I think is, we need our primary centers, when a stroke does come, to not just do a plain CT to exclude hemorrhage, but to do a CT angiogram at the time. And find out those who really do have an occlusion, rather than putting them all on the plane and sending them down, and quite a few of them don't actually have an occlusion by the time that they've got here. They haven't been fully investigated, it's just an extra five minutes to do the contrast CT angiogram at the time in the primary center if they're gonna go there. Dr. Michael Froehler:     I think the one other thing I should add, and this is just to reflect back on something Graeme said a minute ago, is that one of the differences we found that really came out of that bypass analysis is the impact on tPA was smaller than we expected. Because the door-to-needle times are actually much longer at the regional hospitals that are not thrombectomy-capable, compared to the thrombectomy centers themselves, that are not only obviously delivering mechanical thrombectomy, but are actually delivering IV-tPA much sooner in terms of door-to-needle times. Dr. Carolyn Lam:               So, room for improvement even for non-endovascular-capable centers, isn't it? Dr. Michael Froehler:     Right, I think it's another area where there's room for improvement. Dr. Carolyn Lam:               Please don't forget to tune in again next week.

Robert Schwentke, Frederick Lau, Max Hubacher and Face2Face host David Peck talk about their new film The Captain, WW II, misplaced power, violence from a perpetrators perspective, the banality of evil and why this is a story about uniforms. Biography Robert Schwentke was born 1968 in Germany. He studied Literature and Philosophy at the Eberhard Karl University in Tuebingen and later earned an MFA in directing from the American Film Institute. Synopsis In the last, desperate moments of World War II, a young German soldier fighting for survival finds a Nazi captain’s uniform. Impersonating an officer, the man quickly takes on the monstrous identity of the perpetrators he is trying to escape from. ---------- For more information about David Peck's podcasting, writing and public speaking please visit his site here or check out the site of his podcast on film, social change and much more. With thanks to producer Josh Snethlage and Mixed Media Sound. Image Copyright: Robert Schwentke and Opus Films. Used with permission.   See acast.com/privacy for privacy and opt-out information.

Se vi state chiedendo “ma l’Erasmus a Tuebingen è solo …..” scherzavamo, nessuno ha mai sentito parlare di Tuebingen! Beh, allora non vi resta che ascoltare la dodicesima puntata di Wanderlust! V’introdurremo infatti, con canzoni, storie e aneddoti tipici del paese teutonico nel mondo dell’Erasmus in Germania con la preziosissima collaborazione, per pura disperazione, del […]

Não durma! Na verdade... durma sim! O sono é essencial para o bom funcionamento dos organismos, mas ainda não se sabe muito bem quais são os organismos com a capacidade de dormir, afinal o que é dormir? Se não sabe ou tem dúvidas sobre o assunto venha escutar mais um Rock com Ciência que está coberto de conteúdo que vai deixa-lo desperto! Participação especial do biólogo Felipe Beijamini, licenciado pela Universidade Estadual do Oeste do Paraná - UNIOESTE (2005), mestre e doutor em Biologia Celular e Molecular, com área de concentração em Fisiologia, pela Universidade Federal do Paraná (2008, 2014) com período sanduíche na Universidade de Toronto (2011). Entre 2014 e 2015 trabalhou como pós-doutorando no Instituto de Psicologia Médica e Neurobiologia Comportamental da Universidade de Tuebingen onde estudou o efeito do sono na habilidade de resolução de problemas. Participantes: Rubens Pazza, Francisco Sassi, Matheus Lunardi e Felipe Beijamini. Descrição da Imagem #PraCegoVer: A figura ilustra a foto do suricato que viralizou no youtube, onde ele aparece estar de vigília mas acaba por dormir em pé, com uma touca em sua cabeça, ao lado esquerdo o símbolo do Rock com Ciência (uma guitarra cujo corpo é formado pela palavra Rock e o braço pela palavra Ciência) saindo "Z" do corpo da guitarra. Aconselhamos o uso de fones de ouvido para escutar os programas. Rock 1 - Blind Guardian - Mr. Sandman Por que dormimos Organismos que dormem Targeted memory reactivation Ciclo sono-vigília Rock 2  - R.E.M. - Losing My Religion Cronobiologia Como, quanto e quando dormir? Exaustão Distúrbios do sono Sonecas Sonhos Rock 3  - Eddie Vedder - Sleeping By Myself Gostou do episódio? Não gostou do episódio? Encontrou alguma falha gritante (ou pequena que seja)? Envie seu comentário! Pode ser aqui mesmo no site ou pelo email contato@rockcomciencia.com.br. Ou ainda pelo Twitter ou Facebook!

Rev. Professor Eamonn Conway is a priest of the Tuam Diocese. He studied philosophy and sociology at the National University of Ireland and theology at St. Patrick's College, Maynooth and the University of Tuebingen. He was awarded his doctorate in theology in 1991 and taught Systematic Theology for seven years at All Hallows College, Dublin. He was appointed Head of Theology and Religious Studies at Mary Immaculate College, University of Limerick in 1999 and in 2000 he also became co-director at the Centre for Culture, Technology & Values.Fr. Eamonn speaks to us this week about his experience of attending the recent Synod of Bishops in Rome on the theme of New Evangelisation which examined ways of trying to renew and bring back people to a more active participation in their faith. Fr. Eamonn explained in general terms what a Synod of Bishops is and what it does and shared a fascinating account of what it meant to be an expert advisor at a Synod and some of the topics that arose there.