Podcasts about postmenopausal

Calcium supplements are everywhere—but do they actually help your bones? In this episode, we unpack the "calcium conundrum" and challenge the common belief that more supplements automatically mean stronger bones. You'll learn why food-based calcium behaves very differently in the body than pharmaceutical calcium supplements, why most studies show little to no benefit of supplements for adult bone health, and how supplements may even carry unexpected health risks. We focus especially on bone health in adults and postmenopausal women, while emphasizing practical, food-first strategies that actually support long-term health. If you're concerned about osteoporosis, fractures, or bone density—and want to make informed, evidence-based choices—this episode will help you rethink calcium from the ground up. Learn why food, not pills, should be your foundation for bone health. Subscribe for more conversations on nutrition, disease prevention, and putting the power of health back in your hands. Key Takeaways Calcium supplements ≠ food calcium Pharmaceutical calcium is metabolized differently and does not offer the same benefits as calcium from whole foods. Most adult studies show supplements don't prevent fractures In typical adult populations, calcium supplements generally fail to improve bone density or reduce fracture risk. Food sources of calcium are safer and more effective Calcium-rich foods support bone health without the cardiovascular, kidney stone, or other risks linked to supplements. Absorption matters more than intake Only 10–50% of dietary calcium is absorbed, depending on diet quality, gut health, medications, activity level, and overall lifestyle. Postmenopausal bone loss isn't just about calcium Bone loss during this stage appears to be largely unrelated to calcium intake alone. Dairy and non-dairy options make adequacy achievable It's not hard to reach ~800–1200 mg/day from food alone, even without supplements. Cultured dairy is preferred Yogurt, kefir, and aged cheeses provide calcium plus beneficial cofactors like protein, vitamin K, and healthy fats. Fortified foods aren't the same as real food Calcium-fortified products still deliver industrial calcium, not naturally integrated nutrients. Supplements can distract from better nutrition Relying on pills may pull focus (and money) away from improving overall diet quality. Bottom line: think food first Your body knows how to handle real food—bone health starts there. This episode is a call to lead your own healthcare journey with humility, curiosity, and intention—so you can make decisions that truly align with your values and goals. Get your copy of Good Food Great Medicine, 4th ed.: https://a.co/d/1D6hIYM   More references can be found at www.GreatMed.org   Would you like Dr. Hassell to answer your question on the air? Contact us! Write us a letter, We love to hear from you! Send questions, comments, and support to:   Phone/text: 503-773-0770 e-mail: info@GreatMed.org   EIN: 88-326-7056   GreatMed.org 4804 NW Bethany Blvd., Suite I-2, #273 Portland OR 97229   This podcast is sponsored by our generous listeners. #wellness #podcast #wellnessforlife #lifestyle #healthandwellnessgoals  

Send us a textWe explain how pelvic ultrasound, saline infusion sonography and ORADS scoring turn confusing reports into clear next steps for cysts, bleeding, and polyps. We share when to watch, when to act and why expert interpretation reduces anxiety and unnecessary tests.• Types of pelvic ultrasound and when each is used• How saline infusion sonography reveals cavity lesions• Benefits of gynecologic imagers vs general radiology• Why image quality and timing affect accuracy• Preparing for scans, full bladder and cycle days• Ovarian cyst basics and common myths• ORADS scoring and what each level implies• Postmenopausal bleeding thresholds and actions• When hysteroscopy is the gold standard• Managing cervical stenosis and procedural comfort• New tech: HyCoSy for tubal patency• Shared decision-making and practical follow-upSupport the show

The Benefits of Matcha for Women in Menopause: Nutritionist Leyla Muedin discusses the potential benefits of matcha for women going through menopause. She explains how matcha, a finely ground green tea powder, offers higher concentrations of antioxidants, amino acids, and phytonutrients compared to regular green tea. These properties can help support cognitive function, mood stabilization, cardiovascular health, and weight management. The episode also touches on the importance of maintaining a healthy lifestyle, emphasizing an anti-inflammatory diet, regular exercise, restful sleep, and meaningful social connections. Leyla highlights how simple daily rituals, such as enjoying a cup of matcha, can provide emotional grounding and routine for women navigating menopause.

This podcast continues the important conversation on osteoporosis, shining a spotlight on how health systems can leverage features within their Electronic Health Record (EHR) systems to improve care for postmenopausal osteoporosis patients.Christen Buseman, Health Systems and Key Accounts Marketing Director at Amgen for the US bone health franchise speaks with Barry Wendt, MD, of St. Elizabeth Healthcare about how health systems can leverage Diagnosis-Aware Notes (DAN) within EHR systems to improve postmenopausal osteoporosis care. This episode is sponsored by Amgen and the participants have been compensated for their time.This episode is sponsored by Amgen.

Low back pain is projected to affect over 800 million people worldwide by 2050. Among women over 55, cases nearly doubled from 89.9 million in 1990 to 176.8 million in 2021 Aging populations are the main driver of this increase, but postmenopausal women face a greater risk due to bone loss, muscle decline, fat redistribution, and immune and inflammatory changes Hormonal shifts during and after menopause alter bone density, disc health, and tissue repair, making the spine more vulnerable to stress and chronic pain Persistent low back pain is linked to multiple chronic conditions, including cardiovascular disease, metabolic disorders, mental health issues, and long-term functional decline Regular movement, stronger core and pelvic floor muscles, improved posture, quality sleep, and stress management are among the most effective ways to lower pain risk and protect your spine

Postmenopausal changes can alter your perception of what is normal for your vision, sometimes in ways that go unseen. For example, blinking a few extra times to shake off the gritty feeling in the morning shouldn't be the norm. In fact, it could be your body dropping hints about something bigger going on with your eye health... and even your brain.  In this episode, Dr. Meenal Agarwal, a board-certified optometrist, explains the connection between eye health and the hormonal shifts postmenopausal women experience, and what you can do about it.  Listen now and start looking into your eyes to improve your health! For show notes, visit https://fivejourneys.com/podcasts/how-postmenopausal-hormone-changes-affect-your-vision/  Follow us on Instagram at https://www.instagram.com/feelfreakingamazing/  Related Episodes Improve Your Vision, with Dr. Bryce Appelbaum Improve ADHD and Dyslexia through Vision Training, with Dr. Bryce Appelbaum Experience a Graceful Perimenopause, with Dr. Mariza Snyder Navigating Menopause: Symptoms, Stages, and Holistic Support, with Zora Benhamou Biohacks for Menopausal Symptom Relief, with Zora Benhamou Unlock Better Sleep and Hormone Balance, with Dr. Deanna Minich Suffering is Optional: Harmonize Your Hormones and Feel Like Yourself Again, with Dr. Lorraine Maita Don't Be Drugged or Dismissed: The Truth About Women's Hormone Health, with Dr. Lorraine Maita How to Detox Estrogen and Prevent Hormone Imbalances, with Kela Smith Hormones for Healthy Aging, with Dr. Daved Rosensweet Find Your Ideal Hormone Balance, with Dr. Daved Rosensweet

In this solo episode of Age Better with Barbara Hannah Grufferman, I break down seven brand-new studies that could change the way you think about your health in your 50s, 60s, 70s and beyond.  From the surprising truth about sitting time, to the power of strength training, to how the Mediterranean diet protects both brain and body—this episode is your shortcut to the latest science on aging well.  Why listen? Because research only matters when you know what it means for you. Each study ends with a clear takeaway you can put into practice today  What You'll Learn  Why breaking up sitting time may be more important than hitting 10,000 steps  The only proven way to fight age-related muscle loss  New evidence that hormone therapy may slow biological aging  Why loneliness is now considered as dangerous as smoking  How a Mediterranean diet can reduce Alzheimer's risk—even with high genetic risk  How the same diet plus calorie reduction and movement cuts diabetes risk by 31%  Why vitamin D deficiency is widespread—and how to fix it  Referenced AGE BETTER Episodes  How Well Are You Aging? VO₂ Max + HRV with Brady Holmer  Creatine for Midlife Women with Dr. Abbie Smith-Ryan  Can Hormone Therapy Help You Live Longer with Dr. Margaret Nachtigall  Feeling Lonely? We Can Fix That with Joyce Shulman  Fight Dementia After Menopause with Dr. Margaret Nachtigall  Cheat Sheet: Blood Tests All Postmenopausal Women Should Get  Best Diet for Midlife Women with Gretchen Schueller  This Walking Club Builds Bones, Makes Connections and Helps You Age Better  If you're enjoying Age Better, I'd be so grateful if you left a quick review wherever you listen.      And if there's a topic or question you'd love for me to cover in a future episode, send a note to agebetterpodcast@gmail.com -- I love hearing from you!    Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode of the Movement Logic Podcast, we take a hard look at one of our own core messages and ask: does it have to be heavy to build bone? We unpack a landmark systematic review and meta-analysis that compared more than 100 exercise interventions in postmenopausal women, looking at low, moderate, and high intensities across resistance training, impact, and combined programs.We explain the big picture: resistance training works across intensities, moderate intensity often performs just as well as heavy, and impact-only isn't the standalone solution it's often made out to be. We also highlight how few truly high-intensity trials exist, why that matters, and what it means for interpreting the data.Along the way, we reflect on why it's important to update your message when new evidence emerges, and how this research shifts—not our programming, but our language—around lifting heavy. You'll come away with a clearer understanding of what actually builds bone, what the science says (and doesn't yet say), and why there's more than one effective way to get stronger bones.SIGN UP for the Bone Density Course Interest ListFOLLOW Movement Logic on Instagram00:00 Introduction and Episode Overview09:37 New Research on Exercise Intensity and Bone-Building Exercise for Postmenopausal Women37:08 About the Systematic Review and Meta-Analysis52:20 Meta-Analysis Results Overview54:16 Lumbar Spine Analysis59:00 Femoral Neck Analysis01:01:43 Total Hip Analysis01:02:40 Key Takeaways and Summary01:04:17 Meta-Regression Insights01:09:47 Clinical vs. Statistical Significance01:14:14 Discussion on Bias01:17:26 Engaging with the Community and Expert Opinions01:39:46 Debunking Myths About Women and Heavy Lifting01:40:39 Addressing Misconceptions around Lifting Heavy01:47:25 Cultural Shifts and Women in Strength Training02:05:58 Practical Benefits of Heavy Lifting02:11:44 Final ThoughtsREFERENCES:LIFTMOR Trial and YouTube videoKistler-Fischbacher Systematic Review with Meta-Analysis91: LIFTMOR, Not Less: An Interview with Professor Belinda BeckStu Phillips IG page and postKorpelainen paper100: The Hidden Cost of "Just Do Something" Fitness Advice

This week we have questions on dealing with chronic pain, whether solution focused brief therapy can work with grief, and losing desire in a 30 year marriage. Join our patreon!Listen ad-free, get the show a day early and enjoy the pre-show hang out on the same app you're using RIGHT NOW at www.Patreon.com/Therapy where you can also access our vast library of deep dives, interviews, skill shares, reviews and rants as well as our live discord chat!If you are an Apple user please rate us!If you are a Spotify user, please rate us!Submit a question to the show!Help us reach #1 on Goodpods!Interested in Nick's mental health approach to fitness? Check out www.MentalFitPersonalTraining.comCheck out Dr. Jim's book "Dadvice: 50 Fatherly Life Lessons" at www.DadviceBook.comGrab some swag at our store, www.PodTherapyBaitShop.comPlay Jim's Neurotic Bingo at home while you listen to the show, or don't, I'm not your supervisor.Submit questions to:www.PodTherapy.netPodTherapyGuys@gmail.comFollow us on Social Media:FacebookInstagramTwitterResources:Suicide Prevention Lifeline - 1-800-273-8255.Veterans Crisis Line - 1-800-273-8255.Substance Abuse & Mental Health Services Administration (SAMHSA) National Helpline - (1-800-662-HELP (4357)OK2Talk Helpline Teen Helpline - 1 (800) 273-TALKU.S. Mental Health Resources Hotline - 211

Dynamic Aging Retreat Oct 3-5 2025This Episode's Show NotesJoin Our Newsletter: Movement Colored GlassesIn this episode, Katy Bowman and Jeannette Loram dive into the fascinating relationship between blood sugar, diet, and movement. They unpack how the body regulates blood sugar, what happens when this process breaks down in Type I and Type II diabetes, and why different kinds of activity play such a big role in prevention and management.Katy and Jeannette explain how contracting muscles can pull glucose directly into working cells during exercise—a powerful but site-specific effect—and how long-term training reshapes muscle to take up glucose more efficiently.They also compare the blood sugar benefits of endurance exercise, resistance training, HIIT, stretching, and even light daily movement. Along the way, they highlight two key scenarios: insulin resistance linked to excess weight and inflammation, versus insulin resistance driven by low muscle mass in people with normal weight. For the latter, they stress why resistance training—or “big body work”—is especially essential.CHAPTERS 0:06:00 - Definitions 0:16:00 - The Dynamic Collective 0:17:00 - You Can't Exercise Off Diabetes 0:20:00 - Muscle is the Key Tissue (and the Liver)0:36:30 - Stretching & Light Activity 0:47:00 - Exercise Modality for Blood Sugar Regulation0:54:25 - Listener Question on Lupus brought to you by Peluva 1:09:09 - Blood Sugar Spikes During Exercise BOOKS & RESEARCH PAPERS My Perfect Movement Plan by Katy BowmanI know I should Exercise, But... by Diana Hill & Katy BowmanExercise and GLUT4 by Flores-Opazo et al (2020) Mechanisms of endurance and resistance exercise in type 2 diabetes by Zhao et al (2025)  Sedentary behaviour as a mediator of type 2 diabetes by Hamilton et al (2015) Impact of reduced sitting time or increasing sit-to-stand transitions on blood pressure and glucose regulation in Postmenopausal women by Hartman et al (2025) The impact of standing desks on cardiometabolic and vascular health by Bodker et al (2021) MADE POSSIBLE BY OUR WONDERFUL SPONSORS:Sweet Skins, organic hemp and cotton clothing that is stylish, flexible and designed to move with you, take 20% off with code Movement20Peluva, Five-toe minimalist sports shoes ideal for walking and higher impact activities. Take 15% off with code NUTRITIOUSMOVEMENTIkaria Design, creators of the Soul Seat®, a height adjustable chair that allows you to sit in diverse shapes including cross-legged, take 10% of new inventory with code DNA10Venn Design, beautiful floor cushions and ball seats that keep you moving at home or at the officeEarth Runners, minimalist sandals that mimic being truly barefoot through their grounding technology, take 10% off with code DNA10Smart Playrooms, design and products to keep you and your kids engaged and active at home, take 10% off monkey bars, rock wall panels and holds with code DNA10

In this conversation, Dr. Shawn Tassone discusses the complexities of postmenopausal bleeding, emphasizing the importance of understanding hormone health and the potential implications of bleeding in postmenopausal women. He outlines the diagnostic procedures, including ultrasounds and endometrial biopsies, and explains the significance of various results. Dr. Tassone also addresses the management of endometrial polyps and fibroids, the common occurrence of spotting during hormone replacement therapy, and encourages women to seek medical advice when experiencing unusual symptoms. The conversation aims to educate and empower women regarding their hormonal health and the importance of early detection of potential issues. Episode Highlights: Postmenopausal bleeding should always be investigated. Ultrasounds are crucial for assessing endometrial thickness. Endometrial biopsies can be life-saving tests. Spotting can be common when starting hormone therapy. Polyps are usually benign but can cause bleeding. Understanding hormone levels is key to managing symptoms. Cancers develop over time, not suddenly. Women should not fear hormone replacement therapy. Early detection of uterine cancer is possible and important. Consulting with a physician is essential for any unusual symptoms. Episode Resources: Dr. Shawn Tassone's Practice | https://www.drshawntassone.com Dr. Shawn Tassone's Book | The Hormone Balance Bible Dr. Shawn Tassone's Integrative Hormonal Mapping System | Hormone Archetype Quiz Thank you to our sponsor, Endurance Products Company! After over 25 years of practicing medicine, I'll be the first to tell you that not all supplements are created equal. But when I discovered Dihydroberberine SR, by Endurance Products Company, I was genuinely impressed.  It's highly bioavailable and outperforms standard berberine at significantly lower doses. You can explore their offerings at endur.com. Not only is the science solid, but I love that Endurance Products Company is a family-run American company that has cared about doing things right since 1978. I've started recommending Dihydroberberine to my patients who struggle with blood sugar management, and the results speak for themselves. So much so, that I personally take this supplement for helping to support healthy blood sugar levels, heart health, and tap into how my body uses fats for energy As a special offer for my audience, Endurance Products Company is providing a 10% discount on your order! Simply use the code DRT10 at checkout when you visit endur.com. Medical Disclaimer This podcast and website represent the opinions of Dr. Shawn Tassone and his guests. The content here should not be taken as medical advice and is for informational purposes only. Because each person is so unique, please consult your health care professional for any medical questions.    

In this episode, I sit down with Gina, an older detransitioner with a compelling story that spans decades. We delve into her journey, beginning with her childhood experiences of gender dysphoria in the 1970s, her eventual transition in her 50s, and her decision to detransition in 2023. Gina shares her early crush on a girl and how that shaped her understanding of her identity, leading her to believe she needed to become a boy to express her feelings.We explore the complexities of her transition, including the overwhelming effects of testosterone on her sex drive and how it altered her sexual orientation, making her attracted to men for the first time. Gina reflects on the societal pressures surrounding gender and beauty, and how her past experiences of trauma influenced her decisions. We also discuss the impact of her identity on her relationship with her daughter, highlighting the importance of communication and understanding in parenting. Throughout our conversation, we aim to unpack the nuances of identity, the role of societal expectations, and the emotional turmoil that can accompany such profound life changes.In 1970, at the age of ten, Gina traversed a hill to the neighboring ranch to confess to her friend that she was supposed to be a boy. Forty years later, she “transitioned.” After thirteen years of living as a “trans-man,” she had an awakening that inspired her to begin detransitioning. Now in radical acceptance of her womanhood, she is recovering. Gina's goal is to create a healing space in the country for female detransitioners, crossing a different kind of hill this time, to a new ranch. Gina's art: @aluminum_couture on InstagramGina's Substack: @thisbodyofmine 00:00 Start[00:02:17] Childhood crush and gender identity.[00:05:13] Childhood crush and identity.[00:10:08] Secret crushes and shame.[00:16:50] Coming out as a lesbian.[00:19:11] Attraction and identity transformation.[00:23:46] Masculinity as a protective shield.[00:26:05] Grandiosity in young women's identities.[00:30:50] Identity and rejection in relationships.[00:34:50] Gender identity and self-perception.[00:39:34] Hormonal changes and sexual attraction.[00:44:03] The impact of testosterone on behavior.[00:49:19] Dreams and identity exploration.[00:54:56] Fragility of ego in identity.[00:58:21] Identity crisis and personal anchors.[01:01:05] Suicide prevention and parental responsibility.[01:05:07] Nurturing motherhood and identity.[01:10:06] Grandparenthood and identity transformation.[01:14:36] Identity and self-acceptance journey.[01:18:48] Effects of testosterone on motivation.[01:22:50] Identity and motherhood loss.[01:28:17] Identity acceptance and transformation.[01:30:13] Rediscovering identity through transition.[01:34:54] Emotional stability and external connections.ROGD REPAIR Course + Community gives concerned parents instant access to over 120 lessons providing the psychological insights and communication tools you need to get through to your kid. Use code SOMETHERAPIST2025 to take 50% off your first month.TALK TO ME: book a meeting.PRODUCTION: Looking for your own podcast producer? Visit PodsByNick.com and mention my podcast for 20% off your initial services.SUPPORT THE SHOW: subscribe, like, comment, & share or donate.ORGANIFI: Take 20% off Organifi with code SOMETHERAPIST.Watch NO WAY BACK: The Reality of Gender-Affirming Care. Use code SOMETHERAPIST to take 20% off your order.SHOW NOTES & transcript with help from SwellAI.MUSIC: Thanks to Joey Pecoraro for our song, “Half Awake,” used with gratitude & permission. ALL OTHER LINKS HERE. To support this show, please leave a rating & review on Apple, Spotify, or wherever you get your podcasts. Subscribe, like, comment & share via my YouTube channel. Or recommend this to a friend!Learn more about Do No Harm.Take $200 off your EightSleep Pod Pro Cover with code SOMETHERAPIST at EightSleep.com.Take 20% off all superfood beverages with code SOMETHERAPIST at Organifi.Check out my shop for book recommendations + wellness products.Show notes & transcript provided with the help of SwellAI.Special thanks to Joey Pecoraro for our theme song, “Half Awake,” used with gratitude and permission.Watch NO WAY BACK: The Reality of Gender-Affirming Care (our medical ethics documentary, formerly known as Affirmation Generation). Stream the film or purchase a DVD. Use code SOMETHERAPIST to take 20% off your order. Follow us on X @2022affirmation or Instagram at @affirmationgeneration.Have a question for me? Looking to go deeper and discuss these ideas with other listeners? Join my Locals community! Members get to ask questions I will respond to in exclusive, members-only livestreams, post questions for upcoming guests to answer, plus other perks TBD. ★ Support this podcast on Patreon ★

Postmenopausal bleeding can be an alarming experience, especially when you've gone years without a period. What causes this unexpected bleeding? When should you be concerned? Dr Ceri Cashell joins me to demystify this common but often distressing symptom.We dive into the definition of postmenopausal bleeding - any bleeding that occurs after 12 months without periods - and explore the various causes, from hormone imbalances to more serious conditions that require immediate attention. Dr Ceri uses a brilliant analogy, comparing the uterus to a jumbo jet where multiple hormone "switches" need perfect alignment for smooth operation.For women recently started HRT, bleeding can be a side effect, particularly in the first three to six months or after dosage adjustments. However, Dr Ceri emphasises that certain risk factors like obesity, family history, tamoxifen use, and smoking warrant prompt investigation. We walk through exactly what happens during medical assessment - from initial GP visits to ultrasounds that measure endometrial thickness and potentially hysteroscopy procedures.My own experience with unexpected bleeding after eight years without periods highlights how confronting this symptom can be. Dr. Ceri reminds us that while HRT offers tremendous benefits, it's not a perfect solution and may require personalised adjustments to find your hormone sweet spot. Most importantly, she urges women not to dismiss or normalise symptoms that could indicate something serious - "Women are far too good at sucking things up," she notes, encouraging listeners to prioritise their health concerns.Have you experienced unexpected bleeding after menopause? Don't wait - speak with your healthcare provider today and get the answers and reassurance you deserve.LinksHealthy Hormones WebsiteThank you for listening to my show! Join the conversation on Instagram

In this episode of the Grace & Grit podcast, I sit down with gerontologist and global menopause researcher Zora Benhamou for a fascinating discussion about menopause through a worldwide lens. Drawing from her interviews with over 200 women across 50 countries, Zora shares invaluable insights about how different cultures approach this significant life transition. As a self-described nomad who speaks six languages, Zora brings a unique perspective to our conversation about biohacking menopause and challenging societal stigmas around aging. We explore both the scientific and cultural aspects of menopause, while discussing practical strategies for women to thrive during this transformative phase of life. Key topics we explore: The various stages of menopause and why understanding them is crucial for every woman's journey Practical biohacking strategies for managing common menopause symptoms The connection between gerontology and menopause, and why focusing on longevity matters How different cultures around the world approach and support women through menopause Take a listen and share with the women in your life who might also benefit from the episode. You can listen here: https://graceandgrit.com/podcast-379 MENTIONED IN THIS EPISODE Hack My Age Website: https://hackmyage.com/ Hack My Age Freebies: https://hackmyage.com/freebies/ Hack My Age Instagram: https://www.instagram.com/hackmyage/ *** ⬇️ Tools to rock your second act. ✅ Start Here: https://graceandgrit.com/start-here/ ✅ Listen to the Podcast: https://graceandgrit.com/podcast ✅ Weekly Bit of Grace & Grit: https://graceandgrit.com/rumbleandrise ✅ ️Leave a Podcast Review: https://graceandgrit.com/podcastreview ✅ Rumble & Rise with Courtney: https://graceandgrit.com/readytorumble ✅ Subscribe on YouTube: https://graceandgrit.com/youtube-subscribe ✅ Visit us online: https://graceandgrit.com

In this episode of the Grace & Grit podcast, I sit down with gerontologist and global menopause researcher Zora Benhamou for a fascinating discussion about menopause through a worldwide lens. Drawing from her interviews with over 200 women across 50 countries, Zora shares invaluable insights about how different cultures approach this significant life transition. As a self-described nomad who speaks six languages, Zora brings a unique perspective to our conversation about biohacking menopause and challenging societal stigmas around aging. We explore both the scientific and cultural aspects of menopause, while discussing practical strategies for women to thrive during this transformative phase of life. Key topics we explore: The various stages of menopause and why understanding them is crucial for every woman's journey Practical biohacking strategies for managing common menopause symptoms The connection between gerontology and menopause, and why focusing on longevity matters How different cultures around the world approach and support women through menopause Take a listen and share with the women in your life who might also benefit from the episode. You can listen here: https://graceandgrit.com/podcast-379 MENTIONED IN THIS EPISODE Hack My Age Website: https://hackmyage.com/ Hack My Age Freebies: https://hackmyage.com/freebies/ Hack My Age Instagram: https://www.instagram.com/hackmyage/ *** ⬇️ Tools to rock your second act. ✅ Start Here: https://graceandgrit.com/start-here/ ✅ Listen to the Podcast: https://graceandgrit.com/podcast ✅ Weekly Bit of Grace & Grit: https://graceandgrit.com/rumbleandrise ✅ ️Leave a Podcast Review: https://graceandgrit.com/podcastreview ✅ Rumble & Rise with Courtney: https://graceandgrit.com/readytorumble ✅ Subscribe on YouTube: https://graceandgrit.com/youtube-subscribe ✅ Visit us online: https://graceandgrit.com    

JOIN VEE MINDFUL'S BRAND NEW PRIVATE COMMUNITY. Includes Monthly LIVE Calls with a Book Club - Let's Love and Learn TOGETHER: The V Spot: Love and Learn Lounge for 50 and Over: https://www.veemindful.com/VSpotCommunity (any age over 18 and sex are honestly welcomed - just be kind and an adult.. literally, that's it.) I am trying a few products that claim to help with PAINFUL SEX due to Menopause. Watch the video if you want to learn about these products and your options based on my own experience. Sharing some information about why painful sex happens, what it feels like and how I'm addressing it. TO WATCH THIS VIDEO ON YOUTUBE: https://youtu.be/Jy3S0iDtle4

We receive so many questions about labs that we wanted to take this week's episode and dive deep into some of your most popular questions! Whether you think you need you need certain lab tests drawn based on the symptoms you are experiencing or if you are just curious and thinking about your future health, we'll cover some of the most popular tests today and answer some specific questions around them. Some questions include: I can only invest in one right now… DUTCH test or GI Map? When do I take a DUTCH test if I don't have a regular cycle? What labs can I do while on birth control? If I'm trying to get pregnant, is a DUTCH test a good idea? Can I do a DUTCH test while postmenopausal and on HRT? AND What labs should I ask my doctor for? If you have questions beyond this episode, please DM us and let us know!  Time Stamps: (2:58) Investing In One Lab Test: GI Map or Dutch Test? (8:02) Giving Clients Insight Inside of Vital Spark (8:27) Dutch Test With An Irregular Cycle (12:16) Finding Your Ovulation Window (14:14) Labs On Birth Control (17:57) Dutch Test and Pregnancy (20:30) Dutch Test, Postmenopausal, and on HRT (22:19) What Labs Should You Ask Your Doctor For? (23:55) CMP Test---------------------Follow @vanessagfitness on Instagram for daily fitness tips & motivation. ---------------------Download Our FREE Metabolism-Boosting Workout Program---------------------Join the Women's Metabolism Secrets Facebook Community for 25+ videos teaching you how to start losing fat without hating your life!---------------------Click here to send me a message on Facebook and we'll see how I can help or what best free resources I can share!---------------------Interested in 1-on-1 Coaching with my team of Metabolism & Hormone Experts? Apply Here!---------------------Check out our Youtube Channel!---------------------Enjoyed the podcast? Let us know what you think and leave a 5⭐️ rating and review on iTunes!

Postmenopausal Problems - Geriatric Gynecology in the ED by Christina Shenvi

Stella Duffy is an existential psychotherapist, award-winning writer, actor, director, a campaigner for equality and diversity, and recently completed a PHD in the embodied experience of post menopause. She herself has been postmenopausal for 30 odd years following chemotherapy as a younger woman.In this chat, we get into the deep-rooted cultural stories around menopause and ageing, including Stella's mission to change the negativity younger women often hear about it. She challenges the idea that postmenopause is all about decline, instead seeing it as a transition into a new, thriving chapter.Stella shares some of the amazing stories of women she researched as part of her doctorate on post menopause, showing just how varied the experience can be—some women struggle, some breeze through, and most land somewhere in between. But society tends to focus on fear and loss, making ageing seem like something to dread. Instead, she encourages us to lean into change rather than fight it. Menopause can be tough, sure, but it's also a chance for growth, renewal, and empowerment.Our chat is a powerful reminder that menopause isn't the end—it's just the next phase of an ever-evolving life. Hope you enjoy it.Find out more about Stella's work here; https://stelladuffytherapy.co.uk/about-stella-duffy/Or if you need support with your menopause symptoms or other health issues, contact us here; https://happyhormonesforlife.com/contact

If someone dies from a heart attack or stroke, their death is typically the result of a clot. A clot can form in less than 5 seconds! Usually, your body should form a clot, fix the hole in the artery, then dissolve the clot, but this doesn't always happen.Clots can be caused by the following:•Smoking•Pollution/chemicals•Alcohol•Birth control pills •Stress•Surgery•Endurance sports•Refined starches•Infection•High blood sugar•InflammationExcess calcium in the arteries can also trigger clotting, which can lead to a heart attack or stroke. Postmenopausal women who take large amounts of calcium are at a much greater risk for blood clots. Calcium is involved in over 15 different clotting factors. Vitamin K2 prevents calcium from building up in the soft tissues and arteries. It is found in dairy, butter, and other fatty foods. Always take vitamin D with vitamin K2. Magnesium is another important calcium regulator. It helps prevent calcium from entering the soft tissues, as well as arrhythmias and atrial fibrillation. Nitric oxide can reduce clotting. Vitamin D, L-arginine, and sunlight can increase nitric oxide to help prevent heart attack. Polyphenols, vitamin C, and omega-3 fatty acids all support heart health and may help reduce your risk of clotting.Keto and intermittent fasting can help reduce clotting by reducing inflammation in your arteries. Regular moderate exercise is vital in preventing clotting. Garlic and onion are also essential. Nattokinase, serrapeptase, and bromelain can be taken as supplements to prevent clotting.

Postmenopausal women can build some serious bone AND stay safe with the right instruction and the right load. What's the right load? Dr Belinda Beck can answer that, and in today's episode, she takes us through the results of the LIFTMOR trial. With the right instruction and supervision, postmenopausal women can be lifting 85% of their 1 repetition maximum safely, and make a substantial change in their bone density, strength, and quality of life while doing it. ------------------------------ RESOURCES For more on the LIFTMOR trial: https://pubmed.ncbi.nlm.nih.gov/30861219/

When we think about ageing well, we usually focus on eating right, staying active, and keeping up good habits. But what we don't always consider is how much our emotional health affects our physical health and therefore how well we age.The truth is, in today's fast-paced world, we have become increasingly disconnected from each other, from nature and from ourselves. This disconnect touches every aspect of our lives, affecting how we relate to one another, how we interact with our environment, and even how we care for ourselves.So if we want to make the most of our next chapter and live a happy healthy life, we need to make sure these vital connections are plugged in and thriving.Connection is the 'C' in my EMBRACE formula in my book LIFE AFTER MENOPAUSE​. The book comes with a free downloadable workbook to help you implement your own action plan for your best life after menopause!Learn more here; https://happyhormonesforlife.com/life-after-menopause

In this episode, Dr. Katie Kennedy, a pathologist, discusses the intersection of aging, health, and the effects of alcohol on the body. The conversation explores how alcohol impacts various organs, particularly the liver and brain, and its connection to inflammation and cancer. The role of estrogen in women's health and the implications of aging on inflammation are also examined, providing insights into how these factors affect quality of life. In this conversation, Dr. Kelly Casperson and Dr. Katie Kennedy discuss various aspects of women's health, particularly focusing on postmenopausal issues such as bladder health, the importance of vaginal estrogen, and the role of pathology in understanding these conditions. They delve into the significance of bone health and osteoporosis, emphasizing the need for preventative measures against hip fractures and frailty. The discussion also highlights the connection between breathing, oral health, and overall well-being, advocating for a holistic approach to health that considers the entire body. Takeaways Pathology is the study of diseases and their effects on tissues. Alcohol has a significant impact on liver health, leading to conditions like fatty liver disease. Fatty liver disease can be reversed if caught early and with proper support. Alcohol is classified as a carcinogen, contributing to various cancers. Chronic alcohol consumption can lead to memory loss and increase the risk of dementia. The loss of estrogen during aging creates a synergistic effect with alcohol on brain health. Inflammation is a common response in aging and is linked to estrogen loss. Women metabolize alcohol differently than men, making them more susceptible to its effects. Inflammation can be observed in various tissues, not just localized areas. Understanding the impact of alcohol on health is crucial for making informed choices. Postmenopausal women often suffer from bladder issues that are under-discussed. Vaginal estrogen should be a standard part of women's health care. Thin vaginal mucosa can lead to increased infections and complications. Preventative measures for osteoporosis should start early in life. Hip fractures are a significant health risk for older women. Mouth breathing can lead to various health issues, including sleep apnea. Strengthening the tongue is crucial for preventing aspiration and improving swallowing. Holistic health considers the entire body and its interconnected systems. Education and awareness are key to improving women's health outcomes. Regular health evaluations should include assessments of bone and muscle strength. Dr. Kennedy's Website Dr. Kennedy's IG Order my book "You Are Not Broken: Stop "Should-ing" All Over You Sex Life" Listen to my Tedx Talk: Why we need adult sex ed Take my Adult Sex Ed Master Class: Interested in my sexual health and hormone clinic? Starts February 2025. Thanks to our sponsor Midi Women's Health. Designed by midlife experts, delivered by experienced clinicians, covered by insurance. Midi is the first virtual care clinic made exclusively for women 40+. Evidence-based treatments. Personalized midlife care. https://www.joinmidi.com Thanks to our sponsor Sprout Pharmaceuticals. To find out if Addyi is right for you, go to addyi.com/notbroken and use code NOTBROKEN for a $10 telemedicine appointment. See Full Prescribing Information and Medication Guide, including Boxed Warning for severe low blood pressure and fainting in certain settings at addyi.com/pi To learn more about Via vaginal moisturizer from Solv Wellness, visit via4her.com for 30% off your first purchase of any product, automatically applied at checkout. For an additional $5 off, use coupon code DRKELLY5. Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode, Jill Harris discusses the relationship between osteoporosis and kidney stones, emphasizing the importance of calcium intake and hydration. She addresses a listener's question about managing osteoporosis while preventing kidney stones, highlighting dietary choices and the role of urine calcium levels. The conversation also touches on the significance of strength training for maintaining bone health as one ages.https://kidneystonediet.com/this-will-change-how-you-see-osteoporosis/TakeawaysOsteoporosis can lead to kidney stones due to calcium loss.Dietary choices, such as lowering sugar and salt, are crucial.Natural calcium sources are preferred over supplements.Plant milks may be beneficial but require further research.High urine calcium can indicate underlying health issues.Strength training is essential for maintaining bone health.Regular urine collections can help monitor calcium levels.Consulting a doctor about parathyroid health is important.Postmenopausal women need up to 1,200 mg of calcium daily.A balanced diet and exercise can prevent bone diseases.00:00 Introduction to Osteoporosis and Kidney Stones02:54 Understanding Calcium and Its Role11:41 The Importance of Strength Training for Bone Health——HAVE A QUESTION? _Leave us a voicemail at (773) 789-8764.KIDNEY STONE DIET® APPROVED PRODUCTSProtein Powders, Snacks, and moreWORK WITH JILL _Kidney Stone Diet®Kidney Stone Prevention CourseKidney Stone Diet® Meal PlansSUPPORT THE SHOW _Join the PatreonRate Kidney Stone Diet on Apple Podcasts or Spotify——WHO IS JILL HARRIS? _For over 25 years, Jill Harris has been a kidney stone prevention nurse helping patients reduce their kidney stone risk. Drawing from her work with world-renowned University of Chicago nephrologist, Dr. Fred Coe, and the thousands of patients she's worked with directly, she created the Kidney Stone Diet®. With a simple, self-guided online video course, meal plans, ebooks, and group coaching, Kidney Stone Diet® is Jill's effort to help as many patients as possible stop making kidney stones for good.

Are Conventional Medications Hurting your Bone Health? In this episode of the Longevity podcast, I an joined by Dr. John Neustadt, a renowned expert in integrative medicine, author, and speaker to discuss actionable tips on supplements, diet, hormone replenishment, and effective exercises to help maintain strong bones and reduce fracture risks. Valuable information for anyone looking to improve their bone health and overall well-being! Dr. Neustadt has dedicated his career to advancing the field of medicine through a holistic approach. He has authored multiple books and peer-reviewed articles, and his insights have made a substantial impact on our understanding of chronic diseases and aging. Dr. Neustadt's commitment to patient care and his innovative thinking make him a leading voice in health and wellness today.   Thank you to our sponsors for making this episode possible: Timeline: Use code NAT10 for 10% your order at https://www.timelinenutrition.com/shop/nutrition SOLTEC: Visit http://soltechealth.com/longevity to learn more and save $100 off your purchase using the code LONGEVITY. Experience the difference for yourself with a 60-day risk free trial. Bioptimizers: BiOptimizers: Go to bioptimizers.com/bionat and enter the coupon code bionat to get 10% off your order.   Find more from Dr. Neustadt: Website: https://www.nbihealth.com/  Facebook: https://www.facebook.com/nbihealth/  YouTube: https://www.youtube.com/user/NBIHealth  LinkedIn: https://www.linkedin.com/in/john-neustadt-nd-1553576/  Twitter: https://twitter.com/JohnNeustadt   Find more from Nathalie: YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ  Join Nat's Membership Community: https://www.natniddam.com/bsp-community  Sign up for Nats Newsletter: https://landing.mailerlite.com/webforms/landing/i7d5m0  Instagram: https://www.instagram.com/nathalieniddam/  Website: www.NatNiddam.com    Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance   What We Discuss: 03:07 Limitations of Bone Density Tests 08:09 Dangers of Medication for Osteoporosis 13:30 Hormone Replacement Therapy for Postmenopausal Bone Loss 25:38 Impact of Medications on Bone Health 36:08 The Role of Hormone Replenishment 40:18 Balancing Calcium Supplementation 41:17 The Role of Calcium and Vitamin D 44:02 Understanding the Safety and Dosage of Calcium Supplementation 45:08 The Different Forms of Vitamin K2 49:34 The Limited Evidence for Magnesium, Boron, and Silica 56:43 The Potential Benefits of Vibration Plates and Exercise   Key Takeaways Bone density tests have limitations and do not accurately predict fracture risk. Fracture risk reduction should be the primary focus in treating osteoporosis. Hormone replacement therapy can effectively maintain and improve bone density in postmenopausal women. Proper nutrition, digestion, and inflammation management are crucial for bone health. MK4, a form of vitamin K2, has been shown to improve bone density and reduce fractures, while MK7 has not. While magnesium is important for overall health, there is limited evidence to support its role in reducing fractures. Exercise, including resistance training and functional exercises, can help improve bone health and reduce fracture risk.  

What if life after menopause wasn't something to fear or dread but instead a vibrant, empowering chapter where you can genuinely thrive physically, mentally, and emotionally? What if your healthiest, most fulfilling, and even most pleasurable years were still ahead? Today's guest is here to help us reframe the narrative around post-menopause and unlock the potential of this next phase. This week, episode 37 of Pleasure in the Pause is about unlocking the power of postmenopausal health and wellness! Are you ready to awaken your sensuality and feel more empowered in your body? Access the FREE Pleasure Upgrade Bundle at https://www.pleasureinthepause.com/gift.Nicki Williams is a qualified nutritionist, speaker, and author of the acclaimed "It's Not You, It's Your Hormones" and “Life After Menopause.” As the founder of Happy Hormones For Life, she has been helping women since 2014 to balance their hormones, reclaim their health, and feel better than ever. With a passion for empowering women to thrive, Nicki brings her extensive knowledge and experience to guide you through life after menopause with confidence and vitality.Highlights from our discussion include:Why stress management is crucial for hormone balance and overall health during the menopausal transition and beyond.Understanding the "feisty four" hormones as key to optimizing your well-being in midlife and beyond.How adopting an 80/20 approach to diet and lifestyle allows for balance, pleasure, and sustainability.Prioritizing rest, relaxation, and connection to nature as powerful tools for healthy aging.Embracing this next chapter of life with intention and focusing on whole-body wellness.The years beyond menopause hold immense potential for growth, fulfillment, and vibrant health. By embracing the wisdom and resilience you've cultivated, you can embark on this next chapter of your life with a renewed sense of purpose and joy. Remember, the best is yet to come - embrace this transformative time with open arms and a heart full of possibility.If you're seeking to reclaim your pleasure and vitality, join Gabriella at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.pleasureinthepause.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ for this enlightening journey into the heart of female pleasure and empowerment.CONNECT WITH NICKI WILLIAMS:InstagramWebsiteBooksCONNECT WITH GABRIELLA ESPINOSA:InstagramLinkedInWork with Gabriella! Get immediate access to practical tools that help you feel more like yourself again during perimenopause and menopause with The Menopause Reset Journal today.

We're living longer than ever before, but for many women, the years post menopause are filled with unanswered questions and unexpected challenges.How do we manage new and lingering symptoms? How do we protect our bones, muscles, and brain health? How do we hold on to our energy, joy, and sense of self in a world that often overlooks us?The truth is, this stage of life is a huge opportunity. With the right tools and mindset, it can be a time to redefine who we are, what we want, and how we choose to age. That's what Life After Menopause is all about – helping you feel empowered and equipped to live well in the years ahead.You can learn more here; https://happyhormonesforlife.com/life-after-menopause

Building muscle during menopause takes a unique stimulus compared to PRE menopause and is also unique during peri and post menopause. Of course there's more. Are you trying to lose weight, gain muscle, prevent osteoporosis, reduce or avoid medication, do you have adrenal fatigue or long haul? In this episode I'll discuss the research on protein and call back to a recent episode about exercise volume for building muscle during menopause. Questions I answer in this episode: How have protein recommendations changed over time (then and now)? [00:08:00] What are women's protein needs during menopause? [00:17:30] What are the effects of protein on building muscle during menopause? [00:11:00] As a refresher, what is the resistance training volume for pre, peri and post menopause? [00:19:50] How important is recovery—and are you doing it right? [00:30:20] Based on RDA (Recommended Dietary Allowance), protein consumption is 0.8g per kg (of body weight) per day. This is about 55 grams of protein for a 150-pound woman — but that's only enough to maintain nitrogen balance and prevent deficiency in sedentary women. It is not enough to help you build muscle. Let me explain why that is true. The reason for that recommendation is important to understand. As you age, anabolic resistance increases, meaning you need more protein and stimulus for muscle protein synthesis. More emerging research indicates “that amount may no longer be an appropriate recommendation.” That statement was the conclusion of a  2020 systematic review and meta-analysis addressing the protein needs of people who are exercising and/or trying to lose weight.  Researchers concluded, “The RDA for protein of 0.8g of protein / kg / day may no longer be an appropriate recommendation.” Scientific Research on Building Muscle During Menopause An interview with Bill Philips, PhD, in May 2024, on the What, When & Why to Exercise for Women 40+, with his primary research focus shifting to that of midlife women, he could already say that the single simplest way to support fat loss and optimal body composition is to increase protein even if you didn't change your caloric intake. A 2022 meta-analysis recommends adults should consume nearly 1.5g of protein / kg / day of protein to maintain and/or augment muscle strength along with resistance training. Small-statured women with low reserves may need even more to prevent muscle loss, strength decline, reduced activity, and increased risk of falls or disease. For active women, whether you are competing or you are intentionally exercising more than 3 times a week for a purpose of achieving fitness or reduced fatness, the 2023 International Society of Sports Nutrition recommends at least 1.5g of protein / kg / day and maybe even more. “Daily protein intake should fall within the mid-to-upper ranges of current sport nutrition guidelines (1.4–2.2 g of protein / kg / day) for women at all stages of menstrual function (pre-, peri-, post-menopausal, and contraceptive users) with protein doses evenly distributed, every 3 to 4 hours, across the day.” One thing to note is that hitting the “ballpark” is not enough. You need to meet the threshold. Whether it's reaching muscle fatigue, breathlessness during exercise, or consistent protein intake, falling short means missing the full benefits. For women in perimenopause, it requires less stimulus than for postmenopausal women with the most hormone decline and most advanced age contributing to anabolic resistance. (inability to gain lean muscle). Training and Protein:  Building Muscle During Menopause When it's recommended to have at least two total body resistance training sessions a week, that minimum may best serve: Women in perimenopause Those with adrenal fatigue or long haul Time constricted Others who require a longer recovery period And within those workouts, there needs to be adequate volume achieved with a number of muscle groups, sets, and weight to muscle fatigue. Postmenopausal women require greater stimulus to build lean muscle. You can aim for 4 HIIT sessions per week and increase resistance training volume if 2 sessions aren't enough, provided protein, sleep, and stress are optimized. The biggest obstacle to exercise is time. The second though is time for recovery. An aging muscle needs more stimulus overload. It needs greater recovery to repair the microtears that are innate to workout out intensely. If you're an active 150 lb postmenopausal woman who wants to improve lean muscle and decrease fat, to reach the upper range of protein that would be 2.2g of protein / kg body weight / day. 68 kg x 2.2 g of protein = 150 g of protein To get this, here is a sample protein consumption per day 50 g x 3 meals 35-40 g x 4 meals For strength training, 15-minute weight training sessions likely lack adequate volume in a session, unless focused on one muscle group. This is useful for beginners learning form or those with adrenal stress or special conditions but may not provide adequate stimulus for muscle growth. In a minimum, do 5-8 sets with some rest between puts you at a need for 15-20 minutes. That's no warm up and cool down. Again, that's a single muscle. Even 30-minute sessions may not allow you adequate stimulus for your muscles. Where to Find Support for Building Muscle During Menopause Personal trainers and fitness instructors, even with degrees or certifications, lack training on menopause and hormonal influences. They're entering the field with the minimum viable knowledge. But eager to help solve a problem like weight loss or earn money, they may only do as well as they know. Advice or training from a 20, or 40-something woman showing what's working for her may not work for the goal you have and the hormone status you've got. Someone trained solely in nutrition on clinical recommendations may not necessarily be up to date on contemporary needs of older women and their hormonal status. It's coming, but until we start demanding it, here's how to advocate for yourself: To determine protein and exercise needs consider: Activity level and goals Current hormone status What you've been doing and how it's working 2.2 g protein per kilogram for active and or postmenopausal women Volume of exercise – from sets of major muscle groups – increases with age Recovery from exercise is as important as the exercise itself In an upcoming podcast, I'll share how to start increasing protein, how to plan a day of protein and position it for support of muscle protein synthesis and blood sugar control. Watch for masterclasses monthly where we deep dive with our members References: https://pmc.ncbi.nlm.nih.gov/articles/PMC7231581/ https://sportsmedicine-open.springeropen.com/articles/10.1186/s40798-022-00508-w https://pmc.ncbi.nlm.nih.gov/articles/PMC10210857/ Other Episodes You May Like: My Post Menopause Workout Week Experiment | What I'm Doing: https://www.flippingfifty.com/my-post-menopause-workout/ Protein Consumption in Menopause (Revisited): https://www.flippingfifty.com/protein-consumption-in-menopause/ Resources: Stronger: Tone & Define https://www.flippingfifty.com/get-stronger/ Flipping 50 Membership: https://www.flippingfifty.com/cafe/

Did you know that up to 68% of postmenopausal women are suffering from a hidden health crisis that could be silently undermining your body's most critical functions? In this eye-opening episode of the Dr. Josh Axe Show, we're diving deep into the world of calcium – the mineral your body desperately needs but might be critically lacking. Dr. Josh Axe reveals the shocking truth about calcium deficiency and its surprising impacts on your overall health. You'll discover: Uncover the top 10 alarming signs of calcium deficiency that most people completely miss Discover why calcium is SO much more than just a bone-building nutrient Learn the best and worst forms of calcium supplements (and which could actually harm your heart) Explore natural, food-based strategies to boost your calcium levels instantly Find out which nutrients are crucial for maximum calcium absorption Understand how calcium impacts not just your bones, but your muscles, nerves, and heart Get expert insights into testing and preventing calcium deficiency Don't miss this game-changing episode that could transform your understanding of nutrition and help you prevent potential health risks. By the end of this podcast, you'll have a comprehensive roadmap to optimal calcium health, straight from one of the nation's leading natural health experts. Tune in now and take the first step towards a stronger, healthier you! #calciumhealth #naturalnutrition #wellnesstips Want more of The Dr. Josh Axe Show? Subscribe to the YouTube channel. Follow Dr. Josh Axe Instagram Twitter Facebook TikTok Website ------  Staying healthy in today's world is an upstream battle. Subscribe to Wellness Weekly, your 5-minute dose of sound health advice to help you grow physically, mentally, and spiritually. Every Wednesday, you'll get: Holistic health news & life-hacks from a biblical world view Powerful free resources including classes, Q&As, and guides from Dr. Axe The latest episodes of The Dr. Josh Axe Show Submit your questions via voice memo to be featured on the show → speakpipe.com/drjoshaxe  ------  Links:  https://ods.od.nih.gov/factsheets/Calcium-HealthProfessional/#:~:text=Postmenopausal%20women,loss%20after%20menopause%20%5B1%5D.  https://www.bmj.com/content/342/bmj.d2040#:~:text=The%20size%20of%20this%20increase,substantial%20population%20burden%20of%20disease%2C  Ads: Even if your bloodwork looks "normal," your symptoms could point to Cell Danger Response (CDR). Discover how to break free from CDR and unlock your full potential at beyondbloodwork.com.

In this episode of the NASP Podcast, Sheila Arquette, President & CEO of NASP, visits with Mary Oates, MD, US Medical Lead, Bone Franchise with Amgen, to discuss post menopausal osteoporosis and what clinical pharmacists can do to support patients.  

Drs. Bilezikian and Cosman discuss the use of anabolic agents in patients with postmenopausal osteoporosis, including the benefits and challenges of utilizing anabolic agents as well as the need for careful patient selection, education. and monitoring. They also review the mechanisms of action, clinical trial data, and rationale of treatment sequencing.

Drs. Cosman and Bilezikian discuss the optimal use of denosumab in patients with postmenopausal osteoporosis and examine how RANK ligand inhibitors differ from bisphosphonate medications. They also share insight into how they personalize therapy with denosumab in patients with postmenopausal osteoporosis.

There is a time to bleed. And there comes a time when all bleeding should stop. Postmenopausal bleeding is not normal.Forward.

The sixth episode in the HRT after breast cancer series features Lisa Colclough and Helen Widner, two breast cancer patients who decided to go down two very different routes. Helen decided to start testosterone pellet therapy whilst being on aromatase inhibitors, whilst Lisa decided to restart her HRT soon after her breast cancer treatment. This mini-series explores hormone replacement therapy (HRT) after breast cancer, a controversial and emotive subject. The conversation focuses on the further understanding of risks and benefits of HRT (hormone replacement therapy) or also MHT (menopause hormone therapy), the emotional impact on patients, and the different views among medical professionals. The goal is to provide understanding for patients seeking HRT after breast cancer and insight for doctors on how to move forward without robust evidence. Dani Binnington, host of the Menopause And Cancer podcast, and founder of the not-for-profit organisation Menopause And Cancer has spoken to hundreds of women who feel like they are in a void and have nowhere to turn to in discussing this difficult topic. Welcome to our HRT after breast cancer series.In this episode we discuss:What was the hardest part about menopause for each of them?We explore why Helen and Lisa thought about using hormone replacement therapy after their breast cancer diagnosis.Lisa discusses not being heard as a patient and why she was made to take action without her doctor's support. Helen discusses the hurdles to accessing testosterone pellet therapy in the UK.Episode Highlights:00:00 Intro.05:13 Postmenopausal risk versus benefits of aromatase inhibitors.08:36 Difficulties with tamoxifen, switched to HRT.11:58 Brain fog impacted daily life, resembling dementia.28:47 Desire for informed discussion about medical decisions.35:45 Research led to considering testosterone implants with AI.Connect with us:For more information and resources visit our website: www.menopauseandcancer.org Or follow us on Instagram @menopause_and_cancerJoin our Facebook group: www.facebook.com/groups/menopauseandcancerchathub

Too busy to read the Lens? Listen to our weekly summary here! In this week's episode we discuss: In this week's issue The exposure to GLP-1 receptor agonist treatment may be associated with a lower risk of developing glaucoma in those with type 2 diabetes. Refractive surgery was shown to be a viable solution to help children with neurodevelopmental challenges who struggle with glasses or contact lenses. Postmenopausal hormone therapy was shown to negatively influence the pathophysiology of glaucoma development. 

It’s Monday in America, time for The World’s Greatest Political Podcast: THE LEFT SHOW! This week, J.M. Bell,  Tiffany and JC talk Kamala Harris, boy howdy! Negative Nancy, weirdos, Project 2025, migrants, JD Vance’s negativity, and The Postmenopausal Female. #655 The World’s Greatest Political Podcast – The LEFT Show  Apple Podcasts, Spotify, and AMAZON too! THE A BLOCK COMMA […]

TIME STAMPS: 00:14 Coach Maili (IG = @healthcoachmais) is a certified keto & carnivore online coach through the Emmerich's program; certified in applied quantum biology through the Institute of Applied Quantum Biology; specializes primarily in helping women over 40 lose weight and optimize their health! She uses a meat based approach to encourage her clients to address their circadian rhythms. 01:52 YAKS - LION DIET approved! Yaks are a “primal” ruminant that still inherits all of its senses, intelligence and agility required to survive in harsh climates and able to fend off most predators that would consider a cow or calf as an easy meal. 06:01 Maili's SEASONAL meat-based diet! 14:29 Davina, from Ireland: “Early bird, owl and circadian cycle. Why people wake up at the same time every night? Do people that work shit [I think she meant to type “shift!”] - living outside the circadian cycle - how does this affect peoples lives? Can you reverse aging after shift work?” 22:22 All about SUNLIGHT and how to benefit from the full spectrum of natural light! 27:09 The impact of NIGHTTIME EATING and its affect on your sleep quality. 31:33 How the Carnivore diet restores your THYROID HEALTH. 36:06 Detrimental effects of THYROID MEDICATIONS and advice on getting off of them. 42:00 What is CIRCADIAN/QUANTUM BIOLOGY?!?! 46:02 Advice for burning stubborn fat for POSTMENOPAUSAL women.  54:34 BAD COACH BUSTED - the Carnivore Diet is not a fad! @carnivorejt, @serena.carnivore, @ryan_healthwealth, @hikmat_jwanroy, @danielleluvsher6 57:14 How to do a “FULL BODY CHECK” to start with your head and identify how every part of your body is feeling!!!  01:03:07 Kelly Hogan's CARNIVORE OOPSIE CAKE! 01:10:04 How Maili's ENDURANCE TRAINING drastically improved since embracing a proper human diet. 01:15:48 DIY SKINCARE ?! How to make your own tallow-based skincare products at home! 01:07:02 Why don't carnivores sunburn? 01:19:04 Inside scoop on Maili's CIRCADIAN METABOLIC RESET GUIDE! (details on her IG!) Looking for some mid-workout entertainment and motivation? Stream The SuperSetYourLife.Com Podcast from any platform. We publish every MONDAY and FRIDAY!

What is the single best thing we can do for our health? What is it that makes the biggest difference? What has the biggest return on investment? Biggest bang for our buck? In a study, people with arthritis who used the "Magic Pill" for 1 hour 3 times per week decreased their pain and disability by 47%. Older patients who did this decreased their progression of Alzheimers and dementia by 50%. For those patients who had diabetes, it reduced their progression by 58%. Postmenopausal women who had 4 hours a week of this treatment had a decrease in the risk of hip fracture by 41%. Right now we hear A LOT about anxiety in our culture.  Many people experience symptoms of anxiety. This treatment reduced anxiety by 48 percent. Of patients suffering with depression, 30% were relieved with a low dose of this treatment and it was bumped up to 47% relief as they increased the dose. Following a group of Harvard alumni for over 12 years those who got the treatment decreased their risk of death by 23% than those who didn't. It is the #1 treatment of fatigue. And this treatment has been shown over and over again to improve quality of life So what's the treatment?! What's the magic pill?  Exercise!!! Mostly Walking. I'm going to say just MOVEMENT! In this episode we discuss the many benefits of movement and how to get more into our day! First, start where you are!! Notice what you are doing! Second, start small! Increase by even just thinking about movement! And third, introduce some new ways to move! I talk about my new favorite: REBOUNDING! Movement is the ONE THING that impacts every aspect of our lives, physical, mental, emotional, social, and spiritual. It truly is the Magic Pill! Listen in for more and follow the links below! 23 1/2 hours DocMikeEvans Hood Fit 15 Minute Trampoline Routine Jump and Jacked 2023 Top Hits Dance Party Rebounding Hotel Maid Study  

I'm sure Carolyn Parker could have become a household name if she had wanted. In her 20s and 30s, Carolyn was one of the most talented all-around mountain athletes in the U.S. — she was one of the first women to become an AMGA certified Rock Guide, climbed 5.12 trad at altitude

Dr. Susan V. Bukata and Freda B. Hannafon, NP‑C, discuss the role of nurse practitioners and physician assistants in the care of patients with postmenopausal osteoporosis, including diagnosis, management, and collaboration with endocrinologists and orthopedic surgeons.

Drs. Kristi Tough DeSapri and Pauline M. Camacho share their insights into best practices for pharmacological management of postmenopausal osteoporosis in women at a high risk for fracture.

Drs. Pauline M. Camacho and Kristi Tough DeSapri share their insights into current and coming advancements in diagnosing postmenopausal osteoporosis, with a focus on identifying women at high risk for fracture.

One of the most common diagnoses we see as pelvic floor PTs is urinary incontinence. This diagnosis is surprisingly very common affecting at least 50% of the vulva owners which increases in prevalence to 75% in women over the age of 65. Unfortunately many of us have been told “that's the price of child birth” or “that's just part of getting older”. While child birth and aging has its affects on the pelvic floor, it doesn't mean that urinary incontinence has to be what you deal with. There are many treatments including pelvic floor PT that can help decrease leakage if not completely eliminate it.Follow us @thev.movementJoin our newsletter or email us info@thevmove.comOur introduction music provided by POW/Sunset Beach/courtesy of www.epidemicsound.comFind a PT near you!Resources:The V Movement's Bladder Diary HandoutNational Association for Continence Bladder Diary

Doctors James Ferriss, Linda Duska, and Jayanthi Lea discuss the promise and the challenges of targeting the immune system with immune checkpoint inhibitors, or ICIs, in cervical and endometrial cancers. They also examine emerging data that support the use of ICIs in recurrent cervical cancer, the potential for curing some patients with advanced endometrial cancer, and molecular factors that make cervical cancer a good target for immunotherapy. TRANSCRIPT Dr. James Stuart Ferriss: Hello, and welcome to the ASCO Daily News Podcast. I'm Dr. James Stuart Ferriss, your guest host of the ASCO Daily News Podcast today. I'm an associate professor of gynecology and obstetrics and the Gynecologic Oncology Fellowship Program Director at Johns Hopkins Medicine. In today's episode, we'll be discussing the use of immunotherapy in cervical and endometrial cancers to advance the treatment of these malignancies. I'm delighted to be joined by two acclaimed experts in this space, Dr. Linda Duska and Dr. Jaya Lea.   Dr. Duska is a professor of obstetrics and gynecology and serves as the associate dean for clinical research at the University of Virginia School of Medicine. Dr. Lea is a professor of obstetrics and gynecology and chief of gynecologic oncology at the University of Texas Southwestern Medical Center.  Our full disclosures are available in the transcript of this episode, and disclosures related to all episodes of the podcast are available at asco.org/DNpod. Drs. Duska and Dr. Lea, it's great to have you on the podcast today.  Dr. Linda Duska: Thanks, Dr. Ferriss.  Dr. Jayanthi Lea: Thanks, Dr. Ferriss.  Dr. James Stuart Ferriss: So, let's get started. In recent years, we've had a revolution in the treatment of advanced endometrial and cervical cancers with improved outcomes for patients treated with immunotherapy. And when we say immunotherapy, we're specifically talking about immune checkpoint inhibitors today. A few of these agents have actually been approved in the United States for the management of these diseases. In our discussion, I'd like to review the promise and challenges of targeting the immune system in patients with advanced endometrial and cervical cancers, as well as review the most recent evidence we have in these spaces.  Let's start with cervix. We've had a lot of improvements in outcomes here, Dr. Lea, and with cervical cancer, we've seen improved overall survival with the incorporation of immunotherapy along with chemotherapy and anti-angiogenic therapy for advanced and recurrent disease. Can you remind us why cervical cancer is a good target for immunotherapy?  Dr. Jayanthi Lea: Yes, Dr. Ferriss. Immunotherapy for cervical cancer is supported by several molecular factors. And I think first and foremost, it's so important to remember that the majority of cervical cancers are HPV-positive. And HPV-positive cancers can induce a high level of inflammation, but this high level of inflammation actually contributes to evasion of immune surveillance. What it also does is that it's responsible for the induction of PD-L1. And we've seen several studies that have shown that cervical cancers express PD-L1 anywhere from 50 to 90 percent of cases. Other pertinent factors to consider are that cervical cancer can be considered a tumor with a high tumor mutational burden. So, the number of somatic mutations that we see in the DNA can be considered as a proxy for neoantigens. And so the higher the level of neoantigens, the more immunogenic the tumor. And then lastly, about 1 in 10 cervical cancers present with microsatellite instability, which is an already established key biomarker for the response team in care.  Dr. James Stuart Ferriss: So, thinking about targeting PD-L1, what clinical evidence do we have that supports the use of immune checkpoint inhibitors in recurrent cervical cancer?  Dr. Jayanthi Lea: We now have several studies that have shown a benefit for immune checkpoint inhibitors. For example, KEYNOTE-158 was a phase 2 basket [trial] that investigated the antitumor activity of pembrolizumab, which is a PD-1 inhibitor, in multiple cancer types. And specifically for patients with previously treated advanced cervical cancer, we were able to see an overall response rate of about 15% in those patients who had PD-L1 positive. And similarly, the EMPOWER CERVICAL-1 study, which was a phase 3 randomized trial that investigated the efficacy of cemiplimab, which is another PD-1 inhibitor, versus investigator's choice of single agent chemotherapy, showed a significant difference in median overall survival and progression-free survival in the cemiplimab group. There are several other studies that have investigated the efficacy of PD-1 or PD-L1 inhibitors in cervical cancer. One specific PD-1 inhibitor is nivolumab. In CHECKMATE-358, nivolumab was associated with an overall response rate of 26% in women who had recurrent/metastatic cervical cancer.  Dr. James Stuart Ferriss: Dr. Duska, do you have any thoughts?  Dr. Linda Duska: I'm really interested in PD-L1 as a biomarker because in the KEYNOTE-A18 study, which we're going to get to, 95% of patients were PD-L1 positive by CPS, which is the scoring system that we use in cervix cancer. And some of the studies that you already mentioned, including BEATcc, which we're also going to talk about, reported results where PD-L1 wasn't even considered. And so it begs the question, since PD-L1 is actually – again, depending on when in the course of disease you look at it, but more recent studies suggest 95% of cervical cancers express PD-L1, and – agnostic is the word I was looking for – it seems at least in BEATcc and similar trials that PD-L1 is agnostic, but I wonder if PD-L1 is really a good biomarker for response to checkpoint inhibitor therapy and I wonder what your thoughts are.  Dr. Jayanthi Lea: I think that's an excellent question. To your point, that's correct that we saw in KETYNOTE-A18 that more than 90% of the patients had PD-L1 positivity and the result is sort of generalizable to all comers. That's still a matter of debate as to how we see PD-L1 as a biomarker to incorporate checkpoint inhibitors in the treatment of patients.  Dr. James Stuart Ferriss: So, let's talk about the use of immune checkpoint inhibitors in the frontline setting. Until recently, we haven't seen much improvement in overall survival since the introduction of anti-angiogenic therapy to the chemotherapy backbone, and that was in GOG 240. Let's talk about the changes that have recently occurred in this space.  Dr. Jayanthi Lea: So, we've had some very exciting data specifically from initially KEYNOTE-826 and its primary metastatic or first line salvage settings. So, KEYNOTE-826, which was a phase 3 randomized, controlled trial was very practice-changing for us because it showed that incorporation of pembrolizumab to the first-line treatment of patients with metastatic or recurrent cervical cancer, really changed the landscape for treatment in this group of patients. So, keep in mind that prior to the study, the standard of care was carboplatin, or cisplatin with paclitaxel plus or minus bevacizumab, which yielded a median overall survival range in anywhere from 13 to 17 months depending on whether you use bevacizumab or not. And then adding pembrolizumab to that regimen, increase the median overall survival to 24 months, which is very promising.  Dr. James Stuart Ferriss: If I remember correctly, KEYNOTE-826 allowed investigators choice, use of bevacizumab, and initially we were unsure about which regimen was best. Has there been additional data since?  Dr. Jayanthi Lea: There has been additional data since. And another study that was done in the same vein was the BEATcc trial, which also looked at the different checkpoint inhibitors, atezolizumab in combination now with bevacizumab and platinum-based chemotherapy. And the control arm for this study was the GOG 240 regimen, which included bevacizumab. And this study showed both a progression-free and overall survival difference. The median overall survival in this study was 32 months with the incorporation of the checkpoint inhibitor to the bevacizumab and platinum-based chemotherapy. So, the way that I look at it is that the BEATcc trial basically confirmed the findings of KEYNOTE-826 and highlights that it is important for us to incorporate checkpoint inhibition with immunotherapy along with bevacizumab when we're treating patients with a recurrence.  Dr. James Stuart Ferriss: Also, folks with primary advanced treatment for cervical cancer, this would be a great regimen, is that right?  Dr. Jayanthi Lea: Absolutely. Primary advance, we would want to use the same regimen for that.  Dr. James Stuart Ferriss: Okay. What about locally advanced in primary treatment? What advances have we seen?  Dr. Jayanthi Lea: So we've had some major changes in that field as well, especially with the recent KEYNOTE-A18 data where pembrolizumab was administered in combination with external beam radiation and concurrent chemotherapy. And this study showed that there was significant and clinically meaningful improvement in progression-free survival compared to chemoradiation alone. Specifically, the progression-free survival at 24 months using pembrolizumab with chemoradiation was 68%, and 57% when in the placebo group. The hazard ratio for disease progression was 0.7 and no new safety signals were observed, which is fantastic, especially given the 0.7 hazard ratio that received PFS.  Dr. James Stuart Ferriss: Yeah, absolutely. These patients with locally advanced cervical cancer often are quite symptomatic, and the prospect of adding chemo, radiation, and now immunotherapy on top of that is really encouraging to see that it was such a well-tolerated regimen. I believe that there were patient-reported outcomes recently reported at SGO.  Dr. Jayanthi Lea: Absolutely. So, the safety profile of pembrolizumab and chemoradiation was consistent with the known profile of the individual treatment components. And no new safety signals emerged in the pembrolizumab chemoradiation arm. So, you're right. It was very well tolerated.  Dr. James Stuart Ferriss: What would you say are the takeaways for folks who are seeing these patients in the community? These locally advanced cervical cancer patients that are now adding immunotherapy in a space that we have not used routinely in the past in terms of combining it with chemo radiation in gynecologic cancer. What are some things they should be looking out for?  Dr. Jayanthi Lea: Well, I think that with the hazard ratio of 0.7 and the patient-reported outcomes showing no new signal, I think we can say that there is a positive benefit-to-risk profile of adding pembrolizumab in combination with chemoradiation, and that we should feel comfortable using this regimen. Now, of course, we have individualized patient care, and be able to know when to use bevacizumab, when to use immunotherapy. So, taking the whole patient into consideration becomes important. But for those individuals who are able to receive these drugs who don't have concrete issues to not receive these drugs [then I'd say we could] incorporate them since the safety profile is set.  Dr. Linda Duska: I would add to that, Dr. Ferriss, that right now we only have FDA approval in the U.S. for stage 3-4A disease, and that's 2014 staging. Mind you, we are now in 2018, so we should be very careful in and follow the correct FIGO staging. But the FDA only gave approval for stage 3-4A disease, even though the study included patients with earlier stage disease and positive nodes.  Dr. James Stuart Ferriss: That's a great point, thank you.  So, Dr. Duska, thinking about endometrial cancer and advanced endometrial cancer, we have seen a similar revolution in the care of patients over the past few years, with major shifts in our approach. Can you remind us how we got here?  Dr. Linda Duska: Yes, I would say in the ‘90s and before, and maybe even in the early 2000s, we used a lot of radiation for endometrial cancer as adjuvant therapy following surgery. The general consensus and what we were all taught was that this was a chemotherapy-resistant disease. And then we learned from a variety of GOG at the time, Gynecologic Oncology Group trials, that this disease is actually chemosensitive. And we went through a series of chemotherapy drugs, ranging from adriamycin cisplatin to taxel adriamycin cisplatin, and finally to taxel and carboplatin, demonstrating that this disease is actually quite chemosensitive.  With this realization came the idea that maybe it would be important to combine chemotherapy and radiation particularly in high-risk endometrial cancer cases, so those with positive nodes or patients with high-risk histology such as clear cell or serous cancers. So two very important trials were done, one of them was PORTEC-3 and the other was GOG-258, which looked at combining chemo and radiation together to see if we could do better than one or the other alone. And they were very different trials, and they looked at different populations of patients and they looked at different things. For example, PORTEC-3 randomized patients to receive chemotherapy and radiation versus radiation alone, while 258 looked at chemotherapy and radiation versus chemotherapy alone. Without going into a great amount of detail, I think what we learned from both of those studies, and I think surprised many of us, that the arms that included chemotherapy, those patients did better.  In fact, the results of GOG-258 can be interpreted – and this is somewhat controversial – but can be interpreted that many of these high-risk patients don't need radiation at all, or perhaps need tumor-directed radiation. For example, chemotherapy followed by tumor-directed radiation either to the vaginal cuff, because the vaginal cuff is at risk for recurrence, or perhaps to an area of concern, maybe the cervix if there were cervical involvement or if there is a particular concern for local recurrence in a particular patient. So, I think the pendulum has swung from almost always using radiation alone to, in more modern day, using chemotherapy and using radiation much more sparingly, and then comes immunotherapy.  Dr. James Stuart Ferriss: So, update us on the results of NRG-GY018 and RUBY?  Dr. Linda Duska: So, we've already talked about the KEYNOTE basket trials, which really contributed a lot to our understanding of the importance of MMR deficiency and microsatellite unstable disease. The KEYNOTE-158 study and the GARNET study showed us how important it was for women with MMRd and MSI endometrial cancer to receive checkpoint inhibition, and actually with remarkable response rates to women who had already been pretreated. But we also learned from the GARNET trial, which included MMRp patients, that the response rates in MMRp were not that great. And that led to KEYNOTE-775, which looked to combine pembrolizumab with a VEGF inhibitor, lenvantinib, to see if we could make the cold tumor hot. And indeed, we could. And not only could we improve the response rate in patients with MMRp tumors, but we could also improve the response rate in patients with MMRd tumors. They did better with the combination than they did with pembro alone.  That led to the idea of combining checkpoint inhibitors with chemo upfront. The idea there was we were going to take paclitaxel and carboplatin, which were our backbone for advanced or recurrent endometrial cancer, and add immunotherapy to that. And to your point, GY018 and RUBY trials did just that. And they allowed MMRd and MMRp patients and combined paclitaxel and carboplatin, either with dostarlimab in the case of RUBY, or pembrolizumab in the case of GY018. These studies, both of which were reported and published in the New England Journal of Medicine last year, showed remarkable findings in the upfront setting and potentially in the curable setting. And the OS data for RUBY were presented at SGO this year and were remarkable for MMRd patients. In the whole population, in the whole group in RUBY, there was a 16.4-month improvement in overall survival with the addition of dostarlimab which is just huge.  When you look at the MMRd group, I think Dr. Powell described the overall survival improvement as unprecedented. I believe that was the word that he used. Also, he called it very robust, with a hazard ratio of 0.32 for the group that got dostarlimab, and a median OS that was not reached. So really remarkable. In addition, in the MMRp group, there was a seven-month improvement in OS that was significant. So that's really amazing in the RUBY trial. It's also of note that the RUBY trial allowed carcinosarcomas, whereas the GY018 study did not. So, I think it's fair to say that these results apply to carcinosarcomas.  It's also really important to note that many of the patients in the immunotherapy group who received placebo, 41% of them got IO in a later treatment line, and these OS data still stand. So that's really interesting and hypothesis-generating. For GY018, we don't have mature OS data yet, so we can't talk about OS. But we saw a similar improvement in PFS in both arms, in the d and the pMMR, with an OS trend in both arms that was also reported at SGO. GY018 was a little bit different though, because they unblinded at the time of the PFS reporting last year, and so those patients were unblinded a lot earlier than the RUBY patients were. So, to interpret the data in that vein, the OS data is not mature, but we anticipate looking at the PFS curves and the preliminary OS curves, that the OS data will also be statistically significantly improved in core pembrolizumab in GY018.  What's also really interesting, and we haven't talked about molecular subtypes, is that when we look at the molecular subtypes in RUBY, and I'm sure we're going to see data on the molecular subtypes in GY018 coming up, different molecular subtypes of endometrial cancer respond differently to IO. And so, there's going to be lots of really interesting data coming our way soon that we're really excited to see, and that will help us triage patients appropriately into treatment regimens.  Dr. James Stuart Ferriss: Dr. Lea, did you have a thought?  Dr. Jayanthi Lea: Yeah, I just wanted to comment that looking at the dMMR survival curve in the file that was presented recently, one thing that really strikes me is the importance of adding the IO at the time of initial treatment. The separation of the curves persists. And, like you just mentioned, Dr. Duska, I mean, some of those patients who received placebo then later on went to get an IO treatment, but at the same time, we still see a vast separation of those curves. So, I think it's really important to note that immunotherapy should be used upfront, especially in dMMR.  Dr. Linda Duska: Yeah, I completely agree with that. And I think that might be– I mean, this is just a hypothesis, but I think that that might be why we saw a difference with the addition of immunotherapy in the MMRp group, because it's possible that the chemotherapy created an immune environment that made the checkpoint inhibitor work more successfully than it would have otherwise. So, a really good point. You definitely need to include dostarlimab or pembrolizumab with the chemotherapy and then as maintenance therapy after.  Dr. James Stuart Ferriss: So, you mentioned, we're increasingly thinking about endometrial cancer in smaller and smaller buckets of patients with very prescribed molecular profiles. We don't yet have enough information to specifically tailor treatment. How are you approaching that today in patients that you see in clinic?  Dr. Linda Duska: Well, the MMR, and I'm interested in what you both are doing also, it's easy with the MMRd and MSI high patients. Those patients all should receive a checkpoint inhibitor, no question. The patients that are p53 mut, I test them for HER2, because we do have data to suggest that atezolizumab or TDX-d might be useful in those individuals, HER2 positive. And then the remaining patients, also called the NSMPs. That's a difficult group. I'm interested to know how you all manage them. I think that's the group where more clinical research is really needed to determine what the best treatment regimen for them is. But I'm interested in both of your thoughts on that.  Dr. James Stuart Ferriss: Dr. Lea?  Dr. Jayanthi Lea: I would have to say that I do exactly like you do, Dr. Duska.  Dr. James Stuart Ferriss: And I would say our approach is very similar. And we have a robust discussion always about the use of immunotherapy with chemotherapy and in patients who are proficient MMR. But I think that most of us believe that the PFS data is certainly compelling. And now the OS data from RUBY, very compelling in both groups. And so, we are routinely recommending the use of immunotherapy along with chemotherapy in these advanced patients.  Dr. Linda Duska: I've heard the argument made that GY018 required measurable disease, and so does not necessarily apply to patients without measurable disease. I'm not sure that I agree with that. I think there were clinical trial reasons why that was a requirement rather than biologic reasons. In addition, as we already discussed, RUBY included carcinosarcomas and GY018 did not. I don't think there's a reason to only use dostarlimab for carcinosarcomas, but that said, I don't know that pembrolizumab has an indication for carcinosarcomas. The devil's in the details, don't get too lost in the weeds. I think the take-home message here is that it's really important to use IO, particularly for the MMRd patients with endometrial cancer, upfront. And based on the OS that we saw in both RUBY and preliminarily in GY018, we may be curing some people with this regimen, and I think we should focus on that. The overall survival for advanced endometrial cancer is not great, and if we can improve that and potentially cure some people, that's a huge advance for our patients.  Dr. James Stuart Ferriss: Do you envision a day that we might even ask the question, “Do we need to do surgery?”  Dr. Linda Duska: So, the rectal data would support that assertion. I'm not sure that endometrial cancer and rectal cancer are the same thing. And I think that taking out a postmenopausal woman's uterus is a lot less morbid than potentially radiating or taking out somebody's rectum. I think a different question would be, is there a day when we would stop doing no dissection? We could definitely debate that, but I don't see that happening. Do you see that happening anytime soon? A stopping of hysterectomy for endometrial cancer? Dr. Jayanthi Lea: I don't see that happening anytime soon. And I think, as you said, taking out the uterus, tubes, and ovaries, it does provide us with some information about whether you're even dealing with a secondary primary. But also, it's from a quality-of-life standpoint. If a woman has a large uterus, that's uncomfortable. Postmenopausal bleeding, avoiding bleeding during the course of treatment, so many reasons why I wouldn't be in too much of a hurry to want to not do surgery for these patients. Dr. James Stuart Ferriss: So, we'll put a plug in for our fellow gynecologic oncologists that we still have a role to play in the incorporation of treatment regimens for patients with advanced uterine cancer. So it's not just medicine, there's still a role for surgery.  Dr. Linda Duska: I think that's very fair, yeah. Dr. James Stuart Ferriss: Okay. I think that's all the time we have for today.  I want to thank our listeners for their time, and you'll find the links to all the studies we've discussed today in the transcript of this episode. And finally, if you value the insights that you hear on the ASCO Daily News Podcast, please take a moment to rate, review, and subscribe wherever you get your podcasts. Thank you.  Dr. Linda Duska: Thank you. Dr. Jayanthi Lea: Thank you. Disclaimer: The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care, and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement.    Find out more about today's speakers: Dr. James Stuart Ferriss Dr. Linda Duska @LDuska Dr. Jayanthi Lea   Follow ASCO on social media:  @ASCO on Twitter  ASCO on Facebook  ASCO on LinkedIn    Disclosures: Dr. James Stuart Ferriss: Honoraria: National Board of Medical Examiners Dr. Linda Duska: Consulting or Advisory Role: Regeneron, Inovio Pharmaceuticals, Merck, Ellipses Pharma Researching Funding (Inst): GlaxoSmithKline, Millenium, Bristol-Myers Squibb, Aeterna Zentaris, Novartis, Abbvie, Tesaro, Cerulean Pharma, Aduro Biotech, Advaxis, Syndax, Pfizer, Merck, Genentech/Roche, Cerulean Pharma, Ludwig Institute for Cancer Research, Leap Therapeutics Patents, Royalties, Other Intellectual Property: UpToDate, Editor, British Journal of Ob/Gyn Dr. Jayanthi Lea: Consulting or Advisory Role: Roche

Marie Forleo joins Dr. Mindy to dig deep into how exactly women can preserve muscle mass as they age. Together they distill complex principles into actionable steps, tailored for both perimenopausal and post-menopausal perspectives. From nuanced insights to personal anecdotes, you will get a blend of depth and entertainment, courtesy of Marie's infectious humor. Whether you're scribbling notes or simply absorbing the wisdom, this episode promises invaluable insights for anyone seeking to maintain muscle through the aging journey. To view full show notes, more information on our guests, resources mentioned in the episode, discount codes, transcripts, and more, visit https://drmindypelz.com/ep230 Check out our fasting membership at resetacademy.drmindypelz.com. Please note our medical disclaimer.

Which route is right for you? Nonoral delivery systems of estradiol bypass the first pass effect. While oral estrogen therapy has been associated with increased factors the cause blood clots, transdermal estrogen appears to have a suppressive effect on these markers. Postmenopausal estrogen therapy involves a nuanced understanding of the mode of administration, individual risk factors, and the latest research findings. Seek a menopause society certified practioner (MSCP) in your area. **This is not medical advice, just medical education. Please ask your doctor medical questions as they pertain to your specific situation. Educational purposes only. .......................................................................... Welcome to the Sky Women community where we are all stronger together. COME SAY HI!!! Instagram: https://www.instagram.com/skywomenshealth https://www.instagram.com/drcarolynmoyers Facebook: https://www.facebook.com/skywomenshealth Email: hello@skywomenshealth.com Sky Women's Health: Https://www.skywomenshealth.com 1125 S Henderson St, Fort Worth, TX 76104 To become a patient: email hello@skywomenshealth.com or call 817-915-9803. #EstrogenSafety #HormoneTherapyInsights #BloodClotRisk #TransdermalvsOral #MenopauseHealth #HormoneDeliverySystems #ACOGGuidelines #WomenHealthPodcast #skywomenshealth --- Send in a voice message: https://podcasters.spotify.com/pod/show/skywomen/message

Many women want to lose weight. To lose weight for active women over 40, they also don't want performance to deteriorate. There are a few things to consider. First, it's not the eat less, exercise more dogma that will get you what you really want.  Most women want energy, tone and definition, and strength for now and later. Better blood sugar control that supports reductions in belly fat and overall insulin sensitivity.  Am I right? But eating less and exercising more - if successful at all during menopause and post - will generally cause the opposite. Less energy, worse mood, poor sleep, less muscle tone, and spirals down from there with long term ramifications to health.  Being active, whether sports performance level or just athletic active, requires energy. There is still a way to juggle goals of maintaining or improving performance while still dropping a few pounds of extra cushioning.  Eating to Lose Weight Active Over 40 Close to the beginning and/or after completion of exercise, peri- and postmenopausal athletes should aim for a bolus of high EAA-containing (~10 g) intact protein sources or supplements to overcome anabolic resistance. Anabolic resistance is the status of muscle loss being more likely than muscle gain and it requires more intense exercise stimulus (strength training), quality protein stimulus, and recovery to overcome it.  An ACSM review of literature stated 20 g protein pre-exercise (and 40 after) for older adults to boost Muscle Protein Synthesis similar to that of a 20 yr old when workout conditions were comparable.  Time pre-exercise fuel for optimal digestion. Within 30 minutes of a workout the easier to digest fuel must be. It's not only a comfort factor, but also the diverted energy for digestion competing with the need for blood flow to deliver oxygen to working muscles. Both digestion and performance will suffer. A “simple shake” with protein powder and unsweetened almond milk or water may be the easy way to go.  If you want carbs, add a half a banana to the shake or have half cup oatmeal with protein powder. Pre-workout, avoid fiber and fat. A mixed meal eaten pre-workout should allow at least 2 ½ - 3 hours to be fully digested. Some will feel most comfortable if this is longer than that (4 hours) if it's following recommendations for high fiber, high protein and high fat.  Given recommendations range from at least 10 to 20 grams of protein pre-workout, below are some examples of protein sources. The more challenged you are with gaining lean muscle (and or are attempting to lose weight while retaining muscle) the higher end of the range you want to be. Lose Weight for Active Women: Women's Guide to Exercise Nutrition High EAA examples of 10 g protein:  Small half a simple shake including protein powder and unsweetened almond milk  Dairy (which does by the way include whey protein) generally pre-exercise wouldn't be recommended due to its influence in mucus production, even if you tolerate which a lot of women don't later in life (but Greek yogurt or cottage cheese are sources of protein- again I don't recommend pre-exercise). ·      2 eggs equal 12 grams of protein (if you tolerate eggs)  ·      ½ cup steel cut oats with protein stirred in ·      Quinoa  Choices vary as to whether you want carbohydrate prior or not to avoid early fatigue during exercise sessions. Overcoming Anabolic Resistance:  A study in the European Journal of Sports Science found higher protein intakes (2-3 times the protein Recommended Dietary Allowance (RDA) of 0.8 g/kg/d) during periods of energy restriction can enhance fat-free mass (FFM) preservation, particularly when combined with exercise. Athletes [and let's include, the very active] aiming to reduce fat mass and preserve FFM should consume protein intakes in the range of ∼1.8-2.7 g kg(-1) d(-1) (or ∼2.3-3.1 g kg(-1) FFM) in combination with a moderate energy deficit (-500 kcal) and the performance of some form of resistance exercise.  What does that look like for you?  Say you weigh 130lbs. Rounding Kgs up to 60.  Based on body weight: 162 g protein  Using the FFM example:  Say you weigh 130lbs and are 25% body fat. Subtracting the fat weight in lbs (32.5) from bodyweight leaves 97.5 Fat Free Mass.  224 g  Using the high range number for each of body weight and FFM-based protein recommendations, the daily protein recommendation then would be 162 – 224 grams of protein daily. That is with the goal of losing weight while resistance training with a moderate calorie deficit.  Taking a median number of 180 g protein with each gram of protein offering 4 kcals means you'd be taking in 720 kcals/day from protein.  Fat = 7 kcals, Carb = 4 kcals.  Prepare to be confused.  Health Organizations Weigh in (Not necessarily on losing weight) Prestigious Organizations Offer These Calculations for a 130lb active woman:  American Dietetic Association (ADA): at least 59 - 106 grams/day. The Centers for Disease Control and Prevention (CDC): 48 - 169 grams/day (10-35% of daily caloric intake). World Health Organization safe lower limit: 49 grams/day. Keep in mind these recommendations vary in goal. The least amount of protein to avoid death or illness is not the same to thrive and add lean muscle, strength and energy. We have a gap.  So, it is of course confusing. We also have emotional relationships to food and beliefs we've held for a long time. Those too are likely factors in your reaction to this episode. You're nodding or shaking. Even though the science is the basis of the content, we don't as humans adopt it readily.  Say You Don't Want to Lose Weight You Want to Maintain Daily protein intake should fall within the mid- to upper ranges of current sport nutrition guidelines (1.4-2.2 g·kg-1·day-1) for women at all stages of menstrual function (pre-, peri-, post-menopausal, and contraceptive users) with protein doses evenly distributed, every 3-4 h, across the day. Eumenorrheic athletes in the luteal phase and peri/post-menopausal athletes, regardless of sport, should aim for the upper end of the range. Let's do the math.  130lb woman  Convert to kg: 59 129 g protein    150lb woman  Convert to kg: 68 149 g protein  This is the equivalent of 1 g protein per lb of body weight. You can keep it easy by remembering that is your daily AND that a “dose” of protein needs to be at least 30gm at a meal. However, if you go higher as suggested for your first meal of the day, the next meal may not need to be as high if you eat within 3-4 hours to keep that muscle protein synthesis up. The alternative is muscle protein breakdown. You're in one or the other. There's really not a neutral.  To Lose Weight for Active Women, Examples of a day of high protein meals:  Pre-Workout: 20 gm protein in a simple shake pre-workout  Or minimally, 12 gm protein in two eggs pre-workout Meal Examples:  45g protein in a post- workout smoothie  51g Salmon (35) + quinoa (6) + Greek-style yogurt (10) with berries  43g Taco Salad with ground Bison (35) + Black beans (8)  46g 6 large Sauteed Scallops (29) + Three-bean salad (8) + Black Bean Brownie (9)  I'm not an advocate of calorie counting. However, a snapshot of the number of calories you take in can be helpful. Many women are too far below what they need, AND too low in protein, AND not lifting weights with adequate intensity or sleeping. Those will add up to muscle loss. You may temporarily think you're successful at the weight loss game, but unless you mitigate it, muscle loss will result in you feeling weaker, less energetic and having a slower metabolism  Weight loss with an on-target activity plan means having a slight caloric deficit with an increased amount of protein from a maintenance phase. Other research I've shared suggests increasing protein by 10-15% above maintenance along with a reasonable deficit if weight loss is needed.  So, let's challenge that.  Do you need weight loss? Or do you need to gain lean muscle? Get very clear. You may need both but someone listening needs to hear this: you don't need weight loss; you need fat loss. That will come with an increase in lean muscle and a decrease in inflammation.  Additionally, to Lose Weight While Active Over 40 Creatine supplementation of 3 to 5 g per day is recommended for the mechanistic support of creatine supplementation with regard to muscle protein kinetics, growth factors, satellite cells, myogenic transcription factors, glycogen and calcium regulation, oxidative stress, and inflammation. Postmenopausal females benefit from bone health, mental health, and skeletal muscle size and function when consuming higher (5g) doses of creatine. References:  Murphy CH, Hector AJ, Phillips SM. Considerations for protein intake in managing weight loss in athletes. Eur J Sport Sci. 2015;15(1):21-8. doi: 10.1080/17461391.2014.936325. Epub 2014 Jul 11. PMID: 25014731. Hector AJ, Phillips SM. Protein Recommendations for Weight Loss in Elite Athletes: A Focus on Body Composition and Performance. Int J Sport Nutr Exerc Metab. 2018 Mar 1;28(2):170-177. doi: 10.1123/ijsnem.2017-0273. Epub 2018 Feb 19. PMID: 29182451. Sims ST, Kerksick CM, Smith-Ryan AE, Janse de Jonge XAK, Hirsch KR, Arent SM, Hewlings SJ, Kleiner SM, Bustillo E, Tartar JL, Starratt VG, Kreider RB, Greenwalt C, Rentería LI, Ormsbee MJ, VanDusseldorp TA, Campbell BI, Kalman DS, Antonio J. International society of sports nutrition position stand: nutritional concerns of the female athlete. J Int Soc Sports Nutr. 2023 Dec;20(1):2204066. doi: 10.1080/15502783.2023.2204066.  Science:  PMID: 37221858; PMCID: PMC10210857. Resources:  5 Day Flip: https://www.flippingfifty.com/5dayflip Flipping 50 Cafe Membership: https://www.flippingfifty.com/cafe/ Flipping 50 Protein: https://www.flippingfifty.com/store/protein-powders/paleo-protein-powder-vanilla/ Other Episodes You Might Like:  How Much Collagen Counts Toward Protein Needs?  https://www.flippingfifty.com/how-much-collagen/ Protein Supplements for Muscle Building: What, When & Why to Exercise for Women 40+  https://www.flippingfifty.com/protein-supplements-for-muscle-building/ Midlife Weight Loss: Burn Body Fat, Balance Your Hormones  https://www.flippingfifty.com/midlife-weight-loss/

In this episode, I'll review the latest hormonal health research, including exciting findings for menopausal and men's hormonal health.  Join me to stay up to date on the latest research in hormonal health. Featured Studies  https://pubmed.ncbi.nlm.nih.gov/36732722/ https://pubmed.ncbi.nlm.nih.gov/34536053/ https://pubmed.ncbi.nlm.nih.gov/35873404/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415500/pdf/medicina-58-01047.pdf https://pubmed.ncbi.nlm.nih.gov/37084590/ https://pubmed.ncbi.nlm.nih.gov/37101856/ https://pubmed.ncbi.nlm.nih.gov/35904028/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188729/pdf/223_2022_Article_991.pdf    Related Resources A previous podcast episode about the EMST150 sleep device:  https://drruscio.com/clinically-proven-breath-device-for-sleep-speech-and-more/  Healthy Gut, Healthy You: https://store.drruscio.com/products/healthy-gut-healthy-you  Courses, free guides, and more: https://drruscio.com/resources?utm_source=youtube&utm_medium=link&utm_campaign=drruscio.com_resources   Timestamps 00:00 Intro  01:16 Low testosterone and sleep quality  06:05 What are normal and low testosterone levels? 07:12 Symptoms of low testosterone  08:47 Diets that may increase testosterone 13:02 Does longjack improve testosterone?  14:32 Longjack vs. Ashwaghanda 16:30 Can HCG injections improve testosterone? 19:15 Can diet reduce menopausal symptoms? 22:38 Does exercise improve hot flashes?  23:20 Postmenopausal symptoms & herbal therapies 24:39 What is the best exercise for postmenopausal bone health? Get the Latest Updates Facebook - https://www.facebook.com/DrRusciodc Instagram - https://www.instagram.com/drrusciodc Pinterest - https://www.pinterest.ca/drmichaelrusciodc DISCLAIMER: The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified healthcare provider before starting any new treatment or discontinuing an existing treatment.   Music featured in this video: "Modern Technology" by Andrew G, https://audiojungle.net/user/andrew_g    *Full transcript available on YouTube by clicking the “Show transcript” button on the bottom right of the video.

Jess is working with a patient who has sustained a low-energy hip fracture. These types of fractures are MOST common in which population? A. High-performance athletes during intense training. B. Postmenopausal women with osteoporosis. C. Children between the ages of 5-10 years. D. Middle-aged men during heavy weightlifting sessions. LINKS MENTIONED: Did you get this question wrong?! If you were stuck between two answers and selected the wrong one, then you need to visit www.NPTEPASS.com, to learn about the #1 solution to STOP getting stuck. Are you looking for a bundle of Coach K's Top MSK Cheatsheets? Look no further: www.nptecheatsheets.com --- Support this podcast: https://podcasters.spotify.com/pod/show/thepthustle/support