Podcasts about icp ms

Send us a textThis episode takes a fun detour into the world of chemistry conspiracy theories! Mike Booth explores the science behind chemtrails vs. contrails and explains how you could actually test for elements like aluminum, barium, lead, and lithium in air samples using ICP-OES and ICP-MS. Learn practical tips for sample collection, how to avoid common interferences, and why trace analysis requires extra care with contamination control.

Send us a textIn this episode, we dive into two real-world stability challenges from our lab. First, we explore a custom tune solution prepared in dilute ammonium hydroxide for ICP-MS, designed to improve lab efficiency. Learn how it performed over time and how to use it effectively for short-term use. Then, we dig into an unexpected silver instability in a low-level multi-element blend — traced back to residual chloride from chromium prep.From method design to trace contamination troubleshooting, this episode is full of practical lessons for anyone working with custom solutions or chasing long-term stability.

Send us a textIn this Q&A episode, we answer analyst questions on EPA Method 200.8, including tuning recommendations, chloride interferences, and digestion techniques for wastewater and drinking water analysis. We also tackle antimony stability, comparing HF and tartaric acid stabilization methods, and discuss key strategies for minimizing contamination in ICP-MS. Plus, our team shares critical HF safety tips, including best practices for handling and emergency response. Have a question you'd like answered on Bench Boost? Send it our way — we might cover it in a future episode!

Historical geochemical datasets can be challenging with variable methods, missing metadata, and shifting detection limits, but they're also an invaluable resource for mineral exploration and mining.In this episode, we break down what qualifies as historical data, common pitfalls to watch for, and best practices for integrating legacy datasets into interpretation workflows. We also explore the newest geochemical data from field-portable and scanning technologies, examining how they complement and contrast with traditional datasets.For this episode we read:Advances in ICP-MS technology and the application of multi-element geochemistry to exploration (Sader and Ryan, 2019)Advances in exploration geochemistry, 2007 to 2017 and beyond (Winterburn et al., 2019)Evaluation of partial digestions for soils to detect a deeply buried VMS Cu-Zn prospect in boreal forests (van Geffen et al., 2014)Major advances in exploration geochemistry, 1998-2007 (Cohen et al., 2010)

Send us a textIn this episode, we continue our journey to Pittcon 2025 with a spotlight on Glass Expansion. Join us as Ryan Brennan shares how Glass Expansion has become a trusted leader in sample introduction systems for ICP-MS and ICP-OES. Discover practical tips for preventing signal drift, maintaining your instruments, and choosing the right accessories to optimize your analysis. Plus, learn how ICP Alley will provide a collaborative hub for ICP analysts to connect with experts and enhance their workflows.Join us next week for a chat with GFS Chemicals!

Send us a textThis episode focuses on the rare and fascinating element ruthenium and osmium, two members of the platinum group metals. Learn the best methods for dissolving these challenging metals using fusion techniques, how to prevent the formation of volatile tetroxides, and key strategies for maintaining stability in solution. We also explore testing considerations for ICP-OES and ICP-MS, including managing interferences and ensuring accurate results in trace analysis.Learn more about our sample prep guides.

Send us a textIron is one of the most common and challenging elements to handle in the lab, both as a key analyte and as a potential contaminant. In this episode, we tackle the nuances of working with iron in the lab. From avoiding contamination in your tools and reagents to selecting the right acid combinations for dissolving metals, alloys, and oxides, we cover it all. Discover how to maintain stability in solution and manage the spectral complexity iron brings to both ICP-OES and ICP-MS.Learn more about our sample prep guides.

Send us a textIn this episode, we explore the rare yet versatile element rhenium, used in high-temperature applications like turbine blades and jet engines. Learn how to effectively prepare rhenium samples, including best practices for dissolving metals and handling oxides through fusion techniques. We also cover tips for testing on ICP-OES and ICP-MS, with insights on avoiding interferences from rare earth elements and osmium.Learn more about our sample prep guides.

Send us a textThis episode focuses on manganese, an essential but often overlooked element in sample preparation and ICP analysis. Learn how manganese behaves in various matrices, from metals and alloys to oxides and organics, and discover tips for avoiding contamination during sample prep. We explore effective dissolution techniques using nitric and hydrochloric acids, strategies to stabilize manganese in solution, and how to manage interferences in ICP-OES and ICP-MS testing.Learn more about our sample prep guides.

Send us a textThis episode explores the challenges and solutions for working with tungsten in sample preparation and ICP analysis. Learn effective techniques for dissolving tungsten metals, alloys, and oxides, including the critical role of HF for stability. We also cover tips for avoiding hydrolysis and preventing tungsten trioxide formation. On the testing side, discover how to manage spectral interferences in ICP-OES and ICP-MS, along with strategies for addressing tungsten's notorious carryover issues.Learn more about our sample prep guides.

In der aktuellen Folge von Reefing Made Simple diskutieren Tolga, Jörg und Corey spannende Themen rund um die Meerwasseraquaristik. Im Fokus stehen das Polypenbild bei Korallen, die Frage, ob ICP-MS-Analysen wirklich notwendig sind, und ob Sand im Aquarium biologisch unverzichtbar ist. Mit fachlichem Tiefgang und praxisnahen Tipps liefern wir Antworten und Anregungen für jeden Riffaquarianer.

Send us a textThis episode unpacks the complexities of preparing and analyzing molybdenum samples across various matrices. From metals and alloys to refractory oxides and biological samples, we explore effective methods for dissolution and stability. Learn about molybdenum's unique behavior, such as its compatibility with ammonium hydroxide matrices and its interactions with HF. Discover tips for avoiding interferences in ICP-OES and ICP-MS testing, including dealing with complex oxide and chloride interferences. Learn more about our sample prep guides.

Send us a textThis episode focuses on the intricacies of preparing and analyzing samples containing niobium and tantalum, two elements with similar geochemistry and behavior. Learn effective methods for dissolving metals, alloys, and oxides using techniques such as HF stabilization and fusion methods, while addressing challenges like signal quenching and purity issues. Discover best practices for ICP-OES and ICP-MS testing, including how to manage interferences from tungsten and rare earth oxides. This episode is packed with actionable insights for anyone working with these unique and often tricky elements.Learn more about our sample prep guides.

Send us a textIn this episode, we explore the versatile and "colorful" chemistry of vanadium in sample preparation and analysis. Learn about effective methods for dissolving vanadium metals, alloys, and oxides, including tips on handling its various oxidation states. Discover practical advice for working with vanadium in different matrices, stability insights, and unique color-change indicators that can help you assess sample prep success. With vanadium being straightforward to test on ICP-OES and ICP-MS, this episode highlights everything you need to achieve reliable results with this stable element.Learn more about our sample prep guides.

Send us a textThis episode covers essential methods for handling titanium in sample prep and analysis, from dissolving titanium alloys and oxides to stabilizing it in solution. Explore the unique challenges of working with titanium, including the need for careful HF handling and tips for preventing hydrolysis. Discover effective techniques for ICP-OES and ICP-MS testing, along with ways to navigate common interferences from elements like scandium and vanadium. This guide will help labs ensure accuracy and stability in titanium analysis, making it a valuable resource for both novice and experienced analysts.Learn more about our sample prep guides.

Send us a textThis episode delves into the complexities of preparing and analyzing samples containing thorium and uranium. Learn how to effectively dissolve metal and oxide samples and explore stability challenges related to HF sensitivity and acid compatibility. We also cover essential ICP-OES and ICP-MS testing strategies, including handling uranium isotopes and understanding the nuances of depleted versus natural uranium sources. Whether you're ensuring accurate results in ICP analysis or navigating radioactive materials, this episode provides valuable insights to enhance your lab's capabilities.Learn more about our sample prep guides.

Willkommen zur neuen Folge von "Reefing made simpel"! Nach unserer Sommerpause sind wir wieder zurück und haben spannende Themen für euch. Besonders freuen wir uns, Corey als neues Mitglied in unserem Podcast-Team begrüßen zu dürfen. Corey bringt eine Menge Erfahrung und frische Ideen mit, die unsere Gespräche bereichern werden. In dieser Folge widmen wir uns mehreren spannenden Themen: Zuerst werfen wir einen Blick auf die Fusion der beiden großen Marken Nyos und ATI. Diese Zusammenarbeit hat in der Aquaristik-Szene für Aufsehen gesorgt, und wir diskutieren, welche Auswirkungen diese Fusion auf die Produkte, Technologien und Innovationen haben könnte. Was können wir als Riffbegeisterte von dieser Verbindung erwarten? Außerdem gibt es ein Update von Tolga und seinem SPS-Becken. Er teilt neue Einblicke in die Entwicklung seines Aquariums und gibt wertvolle Tipps für alle, die ebenfalls SPS-Korallen pflegen möchten. Und natürlich dürfen wir nicht vergessen, dass Corey uns Einblicke in seine Korallenfarm gibt. Er erzählt von seinen Erfahrungen, den Herausforderungen der Zucht und den neuesten Entwicklungen in seiner Farm. Corey bringt spannende Geschichten und jede Menge Wissen über die Welt der Korallen mit, und wir freuen uns darauf, mehr darüber zu erfahren. Diese Episode ist vollgepackt mit wertvollen Informationen und neuen Perspektiven. Also lehnt euch zurück und taucht mit uns ein in die faszinierende Welt der Riffaquaristik. Viel Spaß beim Zuhören!

Send us a textIn this episode, our experts tackle the complexities of working with rare earth elements, from sample prep to interference correction. Listen as they explore methods for dissolving rare earth samples and maintaining stability in solution. The team also delves into the challenges of analyzing rare earths using ICP-OES and ICP-MS, including tips for mitigating oxide interferences and selecting optimal isotopes. Perfect for those dealing with high-purity rare earth samples or navigating their rich spectra, this episode is packed with essential insights for accurate analysis.Learn more about our sample prep guides.

Send us a textIn this episode, we focus on scandium, a key element used frequently as an internal standard in ICP analysis. The team dives into important considerations for keeping scandium stable in solution and avoiding HF sensitivity. They also discuss testing strategies using both ICP-OES and ICP-MS, including how to manage potential spectral interferences and optimize your setup for accurate results. Whether you work with scandium regularly or are looking to fine-tune your techniques, this episode offers essential insights to help you succeed in the lab.Learn more about our sample prep guides.

Adam sits down with Doug Dorrat to clear up some common misconceptions in the reef-keeping hobby. They cover topics from alkalinity, protein skimming, trace elements in salt mixes to the differences between ICP-MS and ICP-OES testing. Doug Dorrat is the owner and operator of Frag Farm UK. He contributes to product development, as well as offering his services as a certified ICP consultant for Fauna Marin (UK and USA).Frag Farm Links:https://www.fragfarm.co.uk/https://facebook.com/fragfarmukhttps://www.instagram.com/fragfarmltd/Frag Garage Links:https://www.patreon.com/BeyondTheReefPodcasthttps://fraggarage.ca/https://www.instagram.com/fraggarage/https://www.youtube.com/channel/UCLkiAJNqvoIRDRTFs34e6Twhttps://www.facebook.com/fraggarageBeyond the Reef Merch!https://fraggarage.ca/product-category/swag/ Hosted on Acast. See acast.com/privacy for more information.

Send us a textThis week, the team discusses the preparation and analysis of samples containing strontium and barium. Discover the similarities between these elements and calcium, from solubility tips to handling HF sensitivity and sulfate contamination risks. The team also provides insights into testing with ICP-OES and ICP-MS, highlighting key interferences to watch for and ways to improve detection limits. Learn more about our sample prep guides.

Send us a textIn this episode of Bench Boost, we explore the best practices for preparing and analyzing samples containing Calcium. From solubility tips to handling trace levels, this episode covers everything you need to know to keep calcium stable in solution and ensure reliable results. We also dive into testing techniques, with insights on using ICP-OES and ICP-MS for calcium detection, including dealing with interferences and optimizing detection limits. Perfect for labs looking to refine their calcium analysis methods.Learn more about our sample prep guides.

Send us a textMike Booth is back with guests Ashley Jones, Liv Forbes, and Autumn Phillips, as they walk you through the critical aspects of preparing magnesium samples—whether you're dealing with metals, oxides, or complex minerals like dolomite. Learn how to avoid common pitfalls such as vigorous reactions during dissolution, potential contamination, and handling HF in your processes. The team also discusses the minimal interferences magnesium faces in both ICP-OES and ICP-MS, making it an easier element to manage in the lab. Perfect for analysts looking to refine their techniques and ensure stable, reliable results in magnesium analysis.Learn more about our sample prep guides. 

Send us a textHost Mike Booth, along with Tech Support Chemist Ashley Jones and R&D Chemists Liv Forbes and Autumn Phillips, discuss the straightforward yet crucial steps to ensure beryllium remains stable in solution. Learn about the acids and methods best suited for different beryllium sample types, how to prevent hydrolyzation, and the key considerations for testing beryllium using ICP-OES and ICP-MS. Whether you're new to working with beryllium or looking to refine your approach, this episode offers valuable insights for achieving reliable results.

Dr. Shoreh Ershadi is the founder of ANITAGING Institute of California and a renowned expert in clinical biochemistry and pharmacology with over 40 years of experience. Dr. Ershadi shares her compelling journey from Iran to the United States, highlighting her unexpected entry into medical technology and the numerous challenges she faced as a woman in science. From setting up clinical labs and pioneering AIDS testing to founding her own antiaging company, Dr. Ershadi discusses her relentless pursuit of scientific innovation and passion for improving human health. The conversation also touches on her entrepreneurial ventures, the role of art in her life, and her vision for a healthier future driven by natural apoptosis-promoting supplements. Guest links: www.Apoptosis.us | www.facebook.com/apoptosisnutraceuticals | www.instagram.com/apoptosisnutraceuticals | www.threads.com/apoptosisnutraceuticals  Charity supported: Save the Children Interested in being a guest on the show or have feedback to share? Email us at podcast@velentium.com.  PRODUCTION CREDITS Host: Lindsey Dinneen Editing: Marketing Wise Producer: Velentium   EPISODE TRANSCRIPT Episode 037 - Dr. Shoreh Ershadi [00:00:00] Lindsey Dinneen: Hi, I'm Lindsey and I'm talking with MedTech industry leaders on how they change lives for a better world. [00:00:09] Diane Bouis: The inventions and technologies are fascinating and so are the people who work with them. [00:00:15] Frank Jaskulke: There was a period of time where I realized, fundamentally, my job was to go hang out with really smart people that are saving lives and then do work that would help them save more lives. [00:00:28] Diane Bouis: I got into the business to save lives and it is incredibly motivating to work with people who are in that same business, saving or improving lives. [00:00:38] Duane Mancini: What better industry than where I get to wake up every day and just save people's lives. [00:00:42] Lindsey Dinneen: These are extraordinary people doing extraordinary work, and this is The Leading Difference. Hello, and welcome back to another episode of The Leading Difference podcast. I'm your host, Lindsey, and today I'm so excited to introduce you to my guest, Dr. Shoreh Ershadi. With over 40 years of expertise in clinical biochemistry and pharmacology, Dr. Ershadi stands at the forefront of scientific innovation in the field of nutraceuticals and supplements. Board certified by the American Academy of Antiaging Medicine and holding dual doctorate degrees, Dr. Ershadi brings a wealth of knowledge and experience to the world. Dr. Ershadi's distinguished credentials, including National Registry in Clinical Chemistry and Toxicology and American Society of Clinical Pathology certifications, underscore her dedication to precision and quality in laboratory practices. Her visionary leadership and unwavering passion for advancing human health has made her a trusted authority in the field. All right. Well, Shoreh, thank you so much for being here today. I'm so excited to speak with you. [00:01:51] Dr. Shoreh Ershadi: Thank you for having me. I'm very excited to talk to you, especially that you're going to talk about medical technology. And that is something that I have been doing or working at for, I would say over 30 years, easy. 1988, I got my license in California. So it's what, 32 years? [00:02:17] Lindsey Dinneen: Yeah. Excellent. Oh my goodness. Well, this leads perfectly into my first question and that is, can you tell us a little bit about yourself and your background and how you got into medtech? [00:02:29] Dr. Shoreh Ershadi: Okay. That is interesting because I was born in Iran and I studied pharmacology. And before I was graduated, the Department of Health in Iran was hiring pharmacists, pharmacologists. So we all went and took the exam and we passed the exam. We were still at the final stages of doing the thesis and going through final stages of graduation. And then they called me and a few other people for an interview. Apparently I had a high mark in the test, which I did not know. So when we went for the interview, and I went to an American school and then later to a British school in Iran, so I was speaking English. At the interview, there was a gentleman who was back in Iran from United States, and he was a PhD in clinical biochemistry, and he asked me to read something in English. And I read it, and he thought that I had it by heart or something, so he flipped the book and found a more difficult page and said, "Okay, read this," and I read that, and he said, "Okay, I'm hiring you for the reference lab." I had absolutely no clue what he was talking about, what was reference lab. I had no intention to even work for Department of Health because I was not even graduated at that time. And then they said, "Okay, start on such and such date." And when I went there the first day, he said he spoke in English and he said, "You're overqualified." Oh my God. What? I mean, it was funny. Without even planning to get into laboratory, I got into the reference lab of Department of Health. And what he was planning to do was to bring College of American Pathologists, the proficiency testing to all the laboratories in Iran. And he wanted someone who would speak English and who could communicate. So first day of my job, I wrote a letter to College of American Pathologists and I said, "Hi, hello, I'm Shoreh Ershadi, I want to buy a thousand proficiency kits." And of course they responded. So just like that, I got into clinical laboratory. And I became the Director of the Quality Control for Department of Health. And that was before the revolution. So, that was my exciting start into laboratory. [00:05:25] Lindsey Dinneen: Yeah, that's an incredible story. Thank you for sharing that. And [00:05:28] Dr. Shoreh Ershadi: Not voluntarily, but serendipitously, yes. [00:05:34] Lindsey Dinneen: There you go. So then at some point, you came to the U. S. and was that transition really difficult? Was it frustrating? Were you excited? Nervous? [00:05:47] Dr. Shoreh Ershadi: There was a part in between before coming to U. S. There was another test by W. H. O., World Health Organization. So I took that test and I passed that test and I got a scholarship to go to medical school in England to do a master's degree. And when I went there, I told them, "I already have a doctorate in pharmacology. I don't want master's. I want to do PhD." And after a few weeks, they said, "Okay, fine, go to PhD. You don't need to do master." So I was in England for about four years. I did my PhD in clinical biochemistry. And I went back to Iran. That was exactly during the revolution. So while I was studying in England, the country in Iran was on fire. It was, things going crazy everywhere. But I went back and I got married. I had my son in Iran, and I was working in a clinical laboratory in one of the best hospitals in Iran, and it got very difficult for women to work. They were saying, " Now you have to wear a scarf. Now, you can't see male patients, you can only talk to female patients." It was not right. So, 1984, I came to United States, I came to California, and with some friends in Iran who had a clinical laboratory, and they were here before me and had started a lab in Orange County, California. I started a branch of the lab in Westwood, in Los Angeles. So that was my first job or position and that was my entrepreneurial side, which now I wouldn't dare to start a life, but then I did. [00:07:51] Lindsey Dinneen: You didn't know the difference then. [00:07:53] Dr. Shoreh Ershadi: Well, yes, I didn't know. I mean, it was a lot easier, I would say. At that point. The lab was not even accepting Medicare or Medi Cal. It was private insurance. I was doing the billing. I was getting the information. I was drawing the patients. I was separating the samples and sending them to the reference lab that was actually running the tests. But I was doing stat CBCs and I was in a medical building and so all the doctors were so nice to send the samples down to me. It worked. So [00:08:33] Lindsey Dinneen: Amazing. Oh my. [00:08:34] Dr. Shoreh Ershadi: Amazing. Yes. Now it sounds really amazing. It's surreal in a way. Yeah. [00:08:42] Lindsey Dinneen: Yeah. Yeah. Well, so, so with that lab and embracing this entrepreneurial journey, and I'm so thankful it worked out so well for you, but were there any moments where you just thought, okay, I've, I, you have such an amazing background. You're so highly educated, you're brilliant. And then you're starting this entrepreneurial journey, which is kind of a different skill set in a way. How was that transition of becoming kind of your own boss and being in charge of everything? [00:09:12] Dr. Shoreh Ershadi: That was pure ignorance. I mean, now I can say then, I thought I knew what I was doing, but it was a fast learning. First that I was in a different country, that I had never been in the United States. Second, that I had a three year old son that I brought with me and my then husband never came, so I got a divorce and I became a single mom. So, and nobody else was from my family was here. So it was very difficult because I had to take him to daycare and then come work and then go pick him up. And then there was a war, the Iraq war had started in Iran and my parents were in Iran and I was going through a divorce, so it was turmoil. And I had to work and learn in a way it was good because it didn't give me time to think about anything else. It was just forward, no looking sideways, no looking backwards. It was just moving forward. But then again, something else happened that made it even more interesting. One of the days that I was at the lab, some guy came and said, "CDL, Central Diagnostic Lab, is looking for a technical director and they've asked me to come and talk to you." I had absolutely no clue if anyone knew me or knew of me or it was the, I mean, a lot of things happened, which, I mean, I'm happy now, but then it changed my life tremendously. And I don't think I've ever talked to anyone about this in this detail. So, Lindsey, I would say you're the first person I'm telling the story of my life. But anyways, I went for an interview and I got hired right away. I had the lab, so I hired someone to do the work that I was doing in the lab. And then I started working at CDL, Central Diagnostic Labs, which was the largest privately owned lab in the United States at that time. There were 1, 200 employees. So that was a very interesting experience on its own because I was introduced to a world that I did not even know what was going on. So, and that was during AIDS testing. Bio-Rad had just come up with Western blot testing and we did the clinical trial, which was very easy in those days. We had AIDS patients and we had a lot of AIDS samples accumulated or saved frozen and we used them to validate the Western blot by Bio-Rad and I went on National TV 1988 and I said, "CDL is the first lab in the world that is doing a confirmation for HIV AIDS testing." So then, that was major. [00:12:40] Lindsey Dinneen: Yes. [00:12:43] Dr. Shoreh Ershadi: But then, then my family came. My father passed away here. It was, again, a lot of complications going on. And one of the other people that I knew asked me to go and partner with them in a lab. Again, my entrepreneurial part took over and I went for the partnership, and I started from scratch. I started Path Labs practically from scratch. There were two pathologists working with Los Alamitos Hospital, and I went there and I started a lab from just buying test tubes, buying, from absolutely nothing. I was there for six years, I think. six or eight years with Path Labs. That was not so successful. After that, I went to Specialty Labs, which is now Quest. Specialty wanted to start a toxicology lab. So, Path Lab was sold. But there was no money made with the partnership and all that. So that was not a very successful six, eight years of my life. Specialty was good. I went to Specialty and I started Department of Toxicology. I don't know if you remember or you were familiar with specialty. Dr. Peters was there and he was the founder, James Peters. He did only immunology testing. They would receive samples and send out everything else to other labs and only do the immunological tests or some specialty tests. When I started the toxicology department, we started getting samples from all over the world. We were running heavy metals and all that. We had an ICP MS and I started running ICP, and the main test that I developed there was measuring iron in the liver biopsy of patients with hemochromatosis. So we would get one spot, in tip of the needle of the liver and then do a measurement and measure the amount of toxicity with iron in hemochromatosis, which was great. I wrote a paper and we were working with Mayo Clinic and they developed the test. So that was very exciting. Then I started the automated lab because all the chemistry. And all the hematology was going out, was sent out. So that brought a lot of money into the lab, but that was not my lab. It was Dr. Peter's lab. It was wonderful. It was nice. But he was the entrepreneur there. So in the year 2000, I started ANTIAGING Institute of California. After passing the specialist chemist license in California, I got National Registry in Certified Chemistry, Certified Toxicology, and then I took the board exam with American Academy of Antiaging Medicine. And that was again entrepreneurial and I started the company, that would be 25 years ago. I've done a lot of consultation. I've been director of lab during COVID. I went back to city health. And I was Director of City Health running 4, 000 COVID patients a night for airports, for schools, for traveling, for a lot of stuff. And then I worked with Siemens Healthineers on regulations for IVDR. So all the kits that Siemens had, over 700 reagent kits that were sold to the laboratories, they need to get the CE mark to be able to be sold in Europe under the new IVDR regulations. And a lot of it had to go through FDA as well because FDA had to approve if there were any changes made to the kits. So I've done a lot of regulation works. I've done a lot of hands on COVID tests, covered it all. Actually, something else that was very interesting. And this, for MedTechs, I would think this would be interesting to know that it's not just one position. And there's so much you can do, if you want to expand your horizon. For about a year, I helped set up extremely high complex laboratory for testing mother's milk, for making milk bank from mother's milk for NICU for children who were born early and the formulas did not work with them. Some of them were so tiny, less than a pound. And so mother's milk bank, it's called Prolacta Bioscience, the company. And I worked there to establish the clinical lab and to get a license for clear and stuff like that. So. [00:18:21] Lindsey Dinneen: Oh! [00:18:21] Dr. Shoreh Ershadi: A lot of good work going into my up and down career, I would say. [00:18:28] Lindsey Dinneen: I love it. Well, first of all, I'm so honored that you were willing to share so much with me. That is. I really appreciate it. And I really appreciate you being willing to talk about some of the amazing moments you've had and the really high, " Yay, we did this," but also some of the moments where it was a little bit tougher and even you being honest and transparent about, the one company didn't do as well as you would have hoped, but you kept going and you are a living testament to resilience and adaptation. [00:18:59] Dr. Shoreh Ershadi: There is no other choice. I would hope that people would have many choices. I mean, you always make choices in life. Even now, this is a choice to talk to you and I appreciate the opportunity because, if I would choose or if I wouldn't know about you, that would be a totally different episode in my life. So I'm open to take chances. You can say that with my experience, living in three different continents and moving and just leaving Iran and coming to us with a three year old, not being here ever before. And then, just jumping in and, but there was no other choice except for moving forward, or we can say, except for success. Because failure was not an option. What would I do? There was nowhere to go back. Sometimes you may have an option to make a U turn and say, "Okay, I don't like this. I want to do something else. I want to stay home." There was no option, no going back. So it was only forward. [00:20:09] Lindsey Dinneen: Yes, absolutely. So, coming here and like you said, having to move forward and I appreciated what you said, you kind of, you couldn't look to the side, you couldn't look back. You had to keep moving forward. How did you go about building a community that could support you, that you could be friends with, and colleagues with, and feel supported coming in from, not having that. [00:20:36] Dr. Shoreh Ershadi: And that was not very difficult. There were many difficult times during that, that I mean, I don't mind talking about it, being a woman, being a young woman, being from a different background there was a lot of resistance. And I see that today as well. I mean, I can't say, "Oh, here I'm in L. A. and Los Angeles is so easy." It's not. I am hoping that women would not maybe experience all the difficulties that I went through. But we're talking about 40 years ago. I came to The States actually July 22nd would be exactly 40 years. I left Iran July 1st, 1984. So this is the 40th anniversary. Being a woman, I thought, when I went to England one of the first things, the professor was my direct supervisor when I worked with him. And I know you can see my face. This is 40 years later. I have no claims, but the professor told me, "You're a beautiful woman. Why do you want to study? Why are you here for PhD?" And I thought that was the greatest insult in my life. So I fought with that professor for four years. [00:22:15] Lindsey Dinneen: No, I'm sorry. [00:22:17] Dr. Shoreh Ershadi: That wasn't easy, but it was so difficult to prove that I am not just a woman or a pretty girl or a young girl or a young woman, or. That was a major fight. I would say that was as difficult as fighting the revolution in Iran, because you wouldn't expect a British professor to say that to you. And I was the only girl, a PhD student, all the others were guys, and this was medical school. And to me, that was very surprising because when I went to University of Tehran, we had probably more girls than guys in the class. Girls were very prone to education in Iran, and they still are. There's still, I think, 60, 65 percent girls in universities, even here. But to hear that was very difficult. That experience repeated itself. in United States over and over till today that I can say I don't feel old. I'm antiaging, but now that I'm an old woman, I still feel that I have to prove myself that I am equal. And sometimes I would say I'm better, but, just to be honest and modest, you want to be treated equal. And that is very difficult. [00:23:53] Lindsey Dinneen: Yeah. Yeah, you're absolutely right. And As much as I would wish things were improving rapidly, I'm not so sure that they are, but what have you found has been helpful in terms of, helping people understand who might come with a bias, but who, helping those people understand, "No I have this education. I am very capable." What are some strategies that you have found that have worked really well for you? [00:24:22] Dr. Shoreh Ershadi: Not many. I have to be honest with you. I mean, if there are a few people, few women, a few even men who are, would be following the conversation, I want them to know that this is not easy. And maybe a part of my success is that I'm a fighter. And I didn't surrender, but I didn't smile my way up. I fought with everyone that went in that direction. And I don't want to get into details, but many of the stronger men would think that if they flirt with you, if they take you out, if they buy dinner for you, then you're going to do what they say. And my story is, just, I have my guards up and I fought. I wouldn't recommend people to fight. Maybe they can find a better solution. I did not find many. Maybe the reason of working separate and starting my own company, maybe one of the major reasons was that I would not have to say yes to power that I did not want to say yes. I worked very hard. I worked hard, long hours. Medtechs, you have to stay there to get the results out. One Christmas. I stayed from December 24th for I would say 72 hours in the lab, maybe two, three hours shower and sleep and go back because we had a lot of toxicology tests that were waiting and results had to go out. And the probe in the I-C-P-M-S was broken. There was no one to replace it during Christmas. It was, we had to borrow from somewhere, FedEx shipping it. Those things happen, you know that, and you have to work hard. It wasn't an easy journey to say, "Oh, I worked four hours a day." And they said, "Thank you. You're so good. Go home." It wasn't like that. [00:26:44] Lindsey Dinneen: Right. Right. Yeah. Well, thank you. I appreciate you sharing that. And so one thing that was really interesting to me, I was looking at your LinkedIn profile and I see that art is a big part of your life in addition to the science and I saw you listed painting and sculpting and I'm wondering how-- well a couple of things-- how did you first get involved in art? And secondly, do you feel that is helpful in terms of having a sort of therapeutic thing to do that kind of maybe helps with some of those harder moments where it's a little frustrating? [00:27:23] Dr. Shoreh Ershadi: Very helpful. But I was as a kid, I started painting at a very young age. And I was always coloring and painting and making things and all that. And my father, a very educated father, he had two master's degree from a University of Texas and came back to Iran. And that's why, we spoke English and we went to English school. So my father was educated and open minded, I can say. But he always said that "You should study art. And don't go to medicine, you'll get old." He passed away in 1988, and I always, when I started Antiaging, I always said "Okay, if you're looking, you will see that I'm antiaging, I didn't age, I went to medical school, I did all the studies." But my logic, first that I love to do this, I mean, it wasn't just you know, forcing myself. I love science. And to this day I do a lot of research. I play with science. You can see the labels are all fancy. I do the paintings. I do all of that. But my logic, more than being scientific, was that this was a career and art would not be a self supporting career, even at younger age. But I always said that if I was a doctor, I could paint, but if I was an artist, I could not do the scientific part or the medical part that I was interested in. But after the divorce, I was in a relationship for 14 years. And I was working hard, raising a son, being a single mother and all that. When that relationship ended after 14 years, the art just popped out. I started painting, sculpting. It was not under control. You can see that, things happen to me, things come out in a certain period. Maybe, I push them down, force them to stay within me, and then they just pop out in different directions. So art came out itself. But there was a period in between that there was no art. Maybe there was too much stress. Maybe there was a lot of, and right now there's no art. Right now it's more entrepreneurial, starting, scientific, all that. But the art pops out every now and then. [00:30:07] Lindsey Dinneen: That's great. Yeah. So speaking of, what you're doing now, I was wondering if you could share a little bit about your company and maybe what you're excited about for its future as you continue along this path. [00:30:19] Dr. Shoreh Ershadi: Okay. That is, this is now where all the passion is. So everything that I have forced inside for all my life is now just coming out into Apoptosis. Apoptosis is a Greek word and it means "falling of the leaves." In science apoptosis, if you Google it, you'll see it means "programmed cell death." So in our bodies in creation or creator or whichever you wanna put it, and I'm sure being a medtech and all the audience, they know there are thousands of reactions inside the body are happening for me just to sit here and breathe and talk. There are thousands and thousands of enzymes and catalysts and metals and oh, whatever is going on. Programmed cell death or apoptosis is a main part of survival. So it's the future of antiaging because we all-- first of all that life expectancy is much longer now. Longevity is longer and younger people do not want to get old. So, at some point I would say my grandmother's generation and my mother is now 95 years old and she's, thank God, healthy and walking and all that, but even she does not want to get old. So, the image of being old and sick is combined together. But we can age without being sick, without getting Alzheimer's, without losing our memory, without getting all these different kinds of diseases. And one major problem is cancer that was much higher with older people and now the statistic is showing that cancer is happening in younger and younger generations. So what apoptosis does is that it's a program in the body. I did not make it. I wish I did, but it's happening all the time. And apoptosis is getting rid of cancer cells, getting rid of damaged cells, getting rid of neurons that cannot connect and synapses with other neurons to take the message over. So if we encourage apoptosis, then all the damaged cells are removed just like falling leaves. They're removed from the body and they're replaced with new energized healthy new cells. Every 10 years, our entire body is regenerated. So why do we get old? We should always stay at a 10 year age. So at 20 years old, we have recycled cells that even though we're growing, growth and youth is defined as between 20 to 25. From 25 to 30, it's sort of stable. There's a plateau. After 30, we start the aging process. So now, as 30 to 60, is still considered not so deep slip going down. It's sort of a plateau up to 60. And then after 60, 70, 80, 90, people are beginning to age. And it shows, I mean, with different diseases, with wrinkles, with memory loss, with all that. So what I'm doing, I'm using nature's product, plant based products, and this has been proven in science that these plants support apoptosis. So, as we get older, just like all the other reactions, apoptosis does not happen at its ultimate way that it should happen. But if we encourage it, for example, we have here, this one is brain beet. This is all beet roots, and it's an organic product. It's all plant based, but it releases nitric oxide. And it works the same way that Viagra works, but it opens all the arteries, it opens the circulation to the brain, to the heart, so why not use it? Why not promote apoptosis the way nature has programmed it in our body, just help it to work better. So that is all my passion right now. [00:35:28] Lindsey Dinneen: Excellent. Excellent. Well, I love that. Thank you for sharing a little bit about it. I'm excited for our listeners to go and learn more about it and, see how they can maybe also take part in the antiaging movement. [00:35:41] Dr. Shoreh Ershadi: Yes, they can partner with us and I would be thrilled. Actually, this is something that maybe I have learned during the long life experience, is that the more partners you have, the more friends you have, the more you share your knowledge, the better it is. Because at some point, it was like people wanted to keep everything to themselves and they didn't want to share or, but right now it's totally different. If they go to Apoptosis.us, they can go to the science section, they can read the papers. And if they would like to partner, I'll be thrilled to work with as many people as possible and take the message out. Yeah, this is a healthy message. This is something that we should all be talking about. [00:36:36] Lindsey Dinneen: Indeed, we should. Yes. Thank you. Well, pivoting the conversation just for fun, imagine that you were to be offered a million dollars to teach a master class on anything you want. It can be in your industry, but it doesn't have to be. What would you choose to teach? [00:36:56] Dr. Shoreh Ershadi: Well, the million dollar would be great. [00:36:59] Lindsey Dinneen: Indeed. [00:37:00] Dr. Shoreh Ershadi: Yes. Yeah. Would we all want that. But yes, I think that right now, as I said, I would use the million dollars to talk about apoptosis all over because I see even young children, every time I see St. Jude's children, and thank you for your donation to Save the Children. I admire that. And I'm hoping that all the children in the world would have a good, healthy future. The world is crazy. You can look at it right now and see that, I can say my experience has been crazy. It doesn't get any better. It's always up and down. Things are happening all over everywhere in the world. And I would like to talk about health, talk about antiaging, talk about Apoptosis and educate more and more of the young people to learn and to avoid all the toxins that we are creating and we have created, with what we're doing with industry and go back to a plant based life, go back to nature, enjoy nature, go back to art, if possible, all the good things that we can do with our lives. [00:38:21] Lindsey Dinneen: Yes, absolutely. And then, how do you wish to be remembered after you leave this world? [00:38:29] Dr. Shoreh Ershadi: Oh, wow. That's a very difficult... a fighter? Survivor? Yep. Strong women? I would support women all the way. Now in Iran, they're saying, Woman Life Freedom. I'm sure you've heard about that. And I cannot tolerate, to see women covered all over with a window to see outside. To me, that is very disturbing. So I would like to see equal opportunity for women and I would like to maybe be remembered as a survivor. [00:39:14] Lindsey Dinneen: Yes, absolutely. And then, final question, what is one thing that makes you smile every time you see or think about it? [00:39:24] Dr. Shoreh Ershadi: Oh, my granddaughter and my grandson. Yes, I have a five year old granddaughter. Her name is Julia and she is my sunshine. She is my life. The grandson is three months old. He's still too young, but he's getting there. [00:39:45] Lindsey Dinneen: Aw! [00:39:48] Dr. Shoreh Ershadi: Getting emotional. [00:39:51] Lindsey Dinneen: I'm so glad. It's that's beautiful. That's wonderful. [00:39:56] Dr. Shoreh Ershadi: Yes, that is continuation of the fight. That is when you see that what you've done is worth the fight, worth the hard work. [00:40:08] Lindsey Dinneen: Absolutely. Absolutely. Yes. Well, this has been amazing. I so appreciate you telling your story and sharing some of it that maybe you haven't done before, and that's I feel very honored. [00:40:23] Dr. Shoreh Ershadi: Yes. [00:40:24] Lindsey Dinneen: Thank you. Thank you for trusting me. [00:40:28] Dr. Shoreh Ershadi: Well, thank you for bringing all of this out. This has been sitting there suffocating, maybe. [00:40:36] Lindsey Dinneen: Yeah. [00:40:37] Dr. Shoreh Ershadi: Thank you. [00:40:38] Lindsey Dinneen: Absolutely. And we are so honored, you mentioned this, but to be making a donation on your behalf as a thank you for your time today to Save the Children, which works to end the cycle of poverty by ensuring communities have the resources to provide children with a healthy, educational, and safe environment. So thank you for choosing that organization to support. And we just wish you the most continued success as you work to change lives for a better world. [00:41:06] Dr. Shoreh Ershadi: Thank you so much, and thank you for having me, and thank you for making me tell the story. Thank you, Lindsey. [00:41:15] Lindsey Dinneen: Of course. And thank you also so much to our listeners for tuning in. And if you're feeling as inspired as I am right now, I would love if you would share this episode with a colleague or two, and we'll catch you next time. [00:41:29] Ben Trombold: The Leading Difference is brought to you by Velentium. Velentium is a full-service CDMO with 100% in-house capability to design, develop, and manufacture medical devices from class two wearables to class three active implantable medical devices. Velentium specializes in active implantables, leads, programmers, and accessories across a wide range of indications, such as neuromodulation, deep brain stimulation, cardiac management, and diabetes management. Velentium's core competencies include electrical, firmware, and mechanical design, mobile apps, embedded cybersecurity, human factors and usability, automated test systems, systems engineering, and contract manufacturing. Velentium works with clients worldwide, from startups seeking funding to established Fortune 100 companies. Visit velentium.com to explore your next step in medical device development.

Send us a Text Message.Our experts are back this week to tackle more of your pressing technical questions. They discuss key topics such as extending the shelf life of your CRMs, identifying and correcting ICP-MS interferences in the challenging mass range of 60-130, and best practices for analyzing bromide on ICP. From understanding the effects of transpiration on your solutions to leveraging isotopic abundance tables for interference management, this episode is packed with valuable insights for anyone working in trace analysis.

Send us a Text Message.This week, we're answering some of the most frequently asked questions in the lab. Our R&D chemists, Autumn Phillips and Madeline Gozzi, along with production manager Joey Burns, offer their insights on the best practices for lithium analysis using ICP-OES and ICP-MS. Discover how to handle spectral interferences, the role of ionization buffers, and why tuning your ICP-MS is crucial for accurate results. Plus, learn how to verify the cleanliness of your DI water and avoid contamination from unexpected sources.

Send us a Text Message.Welcome to a brand-new season of Bench Boost! This season, we're thrilled to feature some special guests and answer all of your burning questions. First up, we present a special three-part interview series with Robert Thomas, a renowned expert with over four decades of experience in the field. Rob has written over 100 technical publications, a comprehensive 14-part tutorial series on ICP-MS, and is the editor of the Atomic Perspectives (AP) column in Spectroscopy magazine. He has also authored six textbooks, with his latest, "Practical Guide to ICP-MS and Other Atomic Spectroscopy Techniques: A Tutorial for Beginners," published in October 2023.In the final interview, Rob talks about his work with the ACS Committee on Analytical Reagents and his editorial contributions to Spectroscopy Magazine. We delve into his collaborative efforts and ongoing projects, shedding light on his significant impact on the field of analytical chemistry and science publishing.

Send us a Text Message.This season, we're thrilled to feature some special guests and answer all of your burning questions. First up, we present a special three-part interview series with Robert Thomas, a renowned expert with over four decades of experience in the field. Rob has written over 100 technical publications, a comprehensive 14-part tutorial series on ICP-MS, and is the editor of the Atomic Perspectives (AP) column in Spectroscopy magazine. He has also authored six textbooks, with his latest, "Practical Guide to ICP-MS and Other Atomic Spectroscopy Techniques: A Tutorial for Beginners," published in October 2023.In the second episode, Mike & Rob discuss the unique challenges faced by spectroscopists working with pharmaceutical and cannabis samples. Rob shares his insights on the specific issues encountered in these industries and offers practical solutions for overcoming these hurdles.

Send us a Text Message.Welcome to a brand-new season of Bench Boost! This season, we're thrilled to feature some special guests and answer all of your burning questions. First up, we present a special three-part interview series with Robert Thomas, a renowned expert with over four decades of experience in the field. Rob has written over 100 technical publications, a comprehensive 14-part tutorial series on ICP-MS, and is the editor of the Atomic Perspectives (AP) column in Spectroscopy magazine. He has also authored six textbooks, with his latest, "Practical Guide to ICP-MS and Other Atomic Spectroscopy Techniques: A Tutorial for Beginners," published in October 2023.Join us in the first episode as we sit down with Rob Thomas to explore his illustrious career in atomic and mass spectroscopy. Rob shares his journey, from his early days in the field to becoming a leading voice in the industry. We'll also discuss the origins of his latest textbook and his motivation behind writing it.

Join our host, Mike Booth, and the team as they navigate through the chapters of our comprehensive Trace Analysis Guide, available on our website, to explore the crucial principles of traceability. From understanding calibration techniques to mastering measurement uncertainty, each episode brings you insights from industry experts and practical tips to enhance your analytical skills.Tune in weekly as we dissect the complexities of trace analysis, chapter by chapter. For more on-demand learning, explore our new virtual ICP academy, IV Ignite, for video courses, downloadable resources, community forums, and so much more.

Adam is joined by Dr. Christoph Denk who runs Oceamo Labs, based out of Austria. Oceamo provides the most comprehensive ICP (MS) and laboratory testing for your tank water. Oceamo is the suggested testing method for Reef Moonshiners users. They go over Adam's recent ICP, looking in depth at each element, the dangers if elevated or depleted, toxicity levels and biological significance. They also discuss the various element inputs and sinks associated with our reef aquariums (watch out for GFO!).https://www.oceamo.com/https://www.facebook.com/OceamoLab/https://www.youtube.com/channel/UC9OJOnOuTFJmUj1y9TrE10w?view_as=subscriberhttps://www.instagram.com/oceamolab/https://www.reefmoonshiners.com/Frag Garage Links:https://www.patreon.com/BeyondTheReefPodcasthttps://fraggarage.ca/https://www.instagram.com/fraggarage/https://www.youtube.com/channel/UCLkiAJNqvoIRDRTFs34e6Twhttps://www.facebook.com/fraggarage Hosted on Acast. See acast.com/privacy for more information.

Robert Thomas is the principal scientist at Scientific Solutions, a consulting company that serves the educational needs of the trace element user community. He has worked in the field of atomic and mass spectroscopy for almost 50 years, including 24 years for a manufacturer of atomic spectroscopic instrumentation. Rob has written overt 100 technical publications, including a 15-part tutorial series entitled, A Beginner's Guide to ICP-MS. He is also the editor and frequent contributor of the Atomic Perspectives column in Spectroscopy magazine, as well as serving on the editorial advisory board of Analytical Cannabis. In addition, Rob has authored 6 textbooks on the fundamental principles and applications of ICP-MS. His most recent book is entitled, A Practical Guide to ICP-MS and Other AS Techniques, which was published in September, 2023. Rob has an advanced degree in analytical chemistry from the University of Wales, UK, and is also a Fellow of the Royal Society of Chemistry (FRSC) and a Chartered Chemist (CChem).

0:00 Intro 3:55 CRITICAL SYSTEMS ARE FAILING 47:17 DIOXIN testing - Australia suffers catastrophic multi-day comms failure - NERC warns the U.S. power grid at high risk of FAILURE during cold weather - US hospitals taken down with cyber attacks - US banking system highly vulnerable to tech configuration failures - Modern society is too centralized, making it highly subject to systemic #collapse - Why #CBDCs will FAIL: They are too centralized and vulnerable to be reliable - Teaser video from our lab: New #dioxin testing mass spec equipment is now online - Smelting #gold and testing it via ICP-MS for elemental analysis - 24K gold is NOT "pure" gold - Why "testing positive" for a chemical doesn't really mean anything - The importance of ongoing #detoxification to rid your body of daily poison exposure - #Nutrition and #superfoods help your body eliminate toxins more quickly For more updates, visit: http://www.brighteon.com/channel/hrreport NaturalNews videos would not be possible without you, as always we remain passionately dedicated to our mission of educating people all over the world on the subject of natural healing remedies and personal liberty (food freedom, medical freedom, the freedom of speech, etc.). Together, we're helping create a better world, with more honest food labeling, reduced chemical contamination, the avoidance of toxic heavy metals and vastly increased scientific transparency. ▶️ Every dollar you spend at the Health Ranger Store goes toward helping us achieve important science and content goals for humanity: https://www.healthrangerstore.com/ ▶️ Sign Up For Our Newsletter: https://www.naturalnews.com/Readerregistration.html ▶️ Brighteon: https://www.brighteon.com/channels/hrreport ▶️ Join Our Social Network: https://brighteon.social/@HealthRanger ▶️ Check In Stock Products at: https://PrepWithMike.com

0:00 McCarthy DUMPED 11:53 ICP-MS instrument 16:31 Other News 1:03:11 Interview with Josh Del Sol To watch the 5G summit for free: https://brightu.com To purchase and stream immediately along with free gifts: https://brighteonuniversity.com/products/the-5g-summit-digital-file For more updates, visit: http://www.brighteon.com/channel/hrreport NaturalNews videos would not be possible without you, as always we remain passionately dedicated to our mission of educating people all over the world on the subject of natural healing remedies and personal liberty (food freedom, medical freedom, the freedom of speech, etc.). Together, we're helping create a better world, with more honest food labeling, reduced chemical contamination, the avoidance of toxic heavy metals and vastly increased scientific transparency. ▶️ Every dollar you spend at the Health Ranger Store goes toward helping us achieve important science and content goals for humanity: https://www.healthrangerstore.com/ ▶️ Sign Up For Our Newsletter: https://www.naturalnews.com/Readerregistration.html ▶️ Brighteon: https://www.brighteon.com/channels/hrreport ▶️ Join Our Social Network: https://brighteon.social/@HealthRanger ▶️ Check In Stock Products at: https://PrepWithMike.com

GDP Script/ Top Stories for Sept 12th Publish Date:  sept 12th From the Henssler Financial Studio Welcome to the Gwinnett Daily Post Podcast Today is Sunday September 10th, and happy 56th birthday to comedian Louis C.K. ****LOUIS C.K.**** I'm Bruce Jenkins and here are your top stories presented by Peggy Slappey Properties Road rage incident in Lilburn leaves one dead, one hospitalized Gwinnett County's new transit plan includes expanded routes and service to Hartsfield-Jackson airport Gwinnett police ID suspect in shooting at Sugarloaf Mills All of this and more is coming up on the Gwinnett Daily Post podcast, and if you are looking for community news, we encourage you to listen daily and subscribe!    Break 1 : M.O.G.          Story 1. Road Rage Lilburn police arrested an 18-year-old suspect, identified as Luis Cruz, following a suspected road rage incident on Sunday afternoon. The incident occurred near the entrance of the Durham Ridge subdivision at the intersection of Harbins and Dickens roads. Two vehicles were involved in the altercation, which resulted in one man's death and another being hospitalized. Cruz is facing charges of felony murder and aggravated assault in connection with the incident, as reported by Lilburn police....…….. read more at gwinnettdailypost.com   STORY 2: Gwinnett County's new transit plan includes expanded routes and service to Hartsfield-Jackson airport Gwinnett County is considering an ambitious Transit Development Plan that aims to expand local and microtransit services while providing connections to Hartsfield-Jackson Atlanta International Airport. The plan outlines five modes of service, including Shared Ride (microtransit), County Ride (local bus service), Quick Ride (high-frequency service), Rapid Ride (bus rapid transit), and Airport Ride (service to the airport). The proposed routes include connections throughout Gwinnett County, improving mobility, and reducing reliance on personal vehicles. County commissioners will vote on whether to adopt the plan, which may lead to a more extensive and interconnected transit system in the region. The microtransit system, similar to a county-run Uber service, is already in operation and is planned for expansion across the county over the next decade. Story 3: Gwinnett police ID suspect in shooting at Sugarloaf Mills A Decatur man named Ethan Dumas, 20, is wanted by Gwinnett County police in connection with a shooting that occurred at Sugarloaf Mills on August 5. Dumas is facing seven charges, including three counts of aggravated assault, criminal damage to property in the first degree, terroristic threats and acts, possession of a firearm during the commission of a crime, and reckless conduct. The shooting, which caused panic at the shopping center, followed a confrontation between two suspects and a shoe kiosk employee. Fortunately, no one was injured by the gunfire. Dumas is described as 5-feet-11-inches tall and around 170 pounds. Authorities are urging anyone with information about his whereabouts to contact Gwinnett County police detectives or Crime Stoppers. A cash reward is being offered for information leading to his arrest and indictment. We have opportunities for sponsors to get great engagement on these shows. Call 770.874.3200 for more info. We'll be right back   Break 2:   Slappey- Tom Wages -  Obits   Story 4: Gwinnett will honor fallen police K9 Blue at dog park this weekend   Gwinnett County is set to honor K9 Blue, a Gwinnett County Police SWAT K9 who tragically lost his life while attempting to track a suspect in 2020. K9 Blue was assisting in tracking a stolen vehicle suspect in Norcross when he was fatally shot during a shootout between police and the suspect. To commemorate his service and sacrifice, a marker will be unveiled at the Graves Park Dog Park in Norcross during a ceremony on Sunday. The event, which begins at 2 p.m., will be emceed by Gwinnett County Police Chief J.D. McClure and feature speeches from various officials, including Gwinnett County Commission Chairwoman Nicole Love Hendrickson and others.       Story 5: Former Gwinnett Commission Chairman Wayne Hill to address Sugar Hill Preservation Society   Former Gwinnett County Commission Chairman Wayne Hill, a Sugar Hill native, is scheduled to speak at the Eagle Theatre on Broad Street. The event, hosted by the Sugar Hill Historic Preservation Society, will take place on Wednesday, September 20, at 7 p.m., with doors opening at 6:30 p.m. Wayne Hill, known for his 12-year tenure as Gwinnett's commission chair, has been actively involved in promoting progress in Gwinnett County and the metro Atlanta area for decades. He played a key role in projects such as the F. Wayne Hill Water Resources Center and the Gwinnett Environmental and Heritage Center. The Sugar Hill Historic Preservation Society is dedicated to preserving and teaching Sugar Hill's history.   Story 6: Grants bring IT opportunities, cutting-edge equipment to Georgia Gwinnett College   Georgia Gwinnett College has received two National Science Foundation grants totaling over half a million dollars to enhance opportunities for science students and acquire cutting-edge equipment. The first grant, worth $203,047, is for an inductively-coupled plasma mass spectrometer (ICP-MS), which can measure very small metal concentrations. This advanced equipment, rare at primarily undergraduate institutions, will attract prospective science students and provide valuable hands-on research experience. The second grant, valued at $300,000, supports the expansion of GGC's Technology Ambassador Program (TAP), aimed at increasing the number of students in IT majors, especially those underrepresented in computing. It will also create a community dedicated to promoting IT outreach and career development workshops. We'll be back in a moment   Break 3:  ESOG – Ingles 3   Story 7: Duluth football 3-0 for the first time since 1985   The Duluth football team has achieved a 3-0 start for the first time in nearly 40 years. They secured this milestone by defeating Chamblee 27-12 at North DeKalb Stadium under the leadership of head coach Cam Jones. Prior to this season, the team's best start was in 2011 when they reached 2-0, but their current 3-0 record is the program's first since 1985. Coach Jones has been instrumental in reviving the team's performance, having taken them to the state playoffs in 2021, their first appearance since 1994. Duluth displayed a strong performance against Chamblee, with key plays leading to touchdowns and a convincing victory.     We'll have final thoughts after this And now, Leah McGrath, corporate dietician at Ingles markets talks with us about foods that help with swollen feet Break 4:  Henssler 60 Thanks again for hanging out with us on today's Gwinnett Daily Post podcast. If you enjoy these shows, we encourage you to check out our other offerings, like the Cherokee Tribune Ledger Podcast, the Marietta Daily Journal, the Community Podcast for Rockdale Newton and Morgan Counties, or the Paulding County News Podcast. Read more about all our stories, and get other great content at Gwinnettdailypost.com. Did you know over 50% of Americans listen to podcasts weekly? Giving you important news about our community and telling great stories are what we do. Make sure you join us for our next episode and be sure to share this podcast on social media with your friends and family. Add us to your Alexa Flash Briefing or your Google Home Briefing and be sure to like, follow, and subscribe wherever you get your podcasts. www.wagesfuneralhome.com  www.psponline.com  www.mallofgeorgiachryslerdodgejeep.com  www.esogrepair.com  www.henssler.com  www.ingles-markets.com  www.downtownlawrencevillega.com  www.gcpsk12.org  www.cummingfair.netSee omnystudio.com/listener for privacy information.

In this episode, we chat with our resident LA-ICP-MS expert, Dr Maurice Brodbeck, on the application of using laser ablation to determine the trace element geochemistry of important ore-forming minerals. Hosted and produced by Dr Claire Geel. --- Send in a voice message: https://podcasters.spotify.com/pod/show/icragorama-podcast/message

In this podcast, Spex is joined by Robert Thomas to discuss the cannabis testing industry and the challenges for inorganic testing of cannabis. Robert (Rob) Thomas is the principal of Scientific Solutions, an educational consulting company that serves the needs of the trace ele­ment user community. He has worked in the field of atomic and mass spectroscopy for almost 50 years, including 24 years for a manufacturer of atomic spectroscopic instrumentation. He has served on the American Chemical Society (ACS) Committee on Analytical Reagents (CAR) for the past 20 years as leader of the plasma spectrochemistry, heavy metals task force, where he has worked very closely with the United States Pharmacopeia (USP) to align ACS heavy metal testing procedures with pharmaceutical guidelines. Rob has written over 100 technical publications, including a 15-part tutorial series on ICP-MS. He is also the editor and frequent contributor of the Atomic Perspectives column in Spectroscopy magazine, as well as serving on the editorial advisory board of Analytical Cannabis. In addition, Rob has authored 5 textbooks on the fundamental principles and applications of ICP-MS. His most recent book is a new paperback version of Measuring Heavy Metal Contaminants in Cannabis and Hemp published in December, 2021. Rob has an advanced degree in analytical chemistry from the University of Wales, UK, and is also a Fellow of the Royal Society of Chemistry (FRSC) and a Chartered Chemist (CChem). Hosted by Patricia Atkins, Spex's Senior Applications Scientist Stay connected with Spex using the links below! Certified Reference MaterialsSample Preparation EquipmentYouTubeInstagramLinkedInSupport the show

Robert Thomas is the principal of Scientific Solutions, a consulting company that serves the training, application, marketing, and writing needs of the trace element user community. He has worked in the field of atomic and mass spectroscopy for more than 45 years, including 25 years for a manufacturer of atomic spectroscopic instrumentation. In recent years, Rob has become a prolific writer on the topic, with more than 100 technical publications to his name. He has authored three textbooks on ICP-MS, the technology labs use to detect trace elements, and in his latest book, titled “Measuring Heavy Metal Contaminants in Cannabis and Hemp”, he applies his knowledge to the nascent cannabis and hemp testing space.  In our conversation we discuss:  What brought Rob to the cannabis and hemp industry How heavy metal testing in the cannabis and hemp industry differs from the pharmaceutical industry Why cannabis and hemp are particularly susceptible to heavy metal contamination The multiple sources of contamination throughout cultivation and processingSteps growers and producers can take to limit heavy metal contamination The current and future regulatory requirements for heavy metal testing  Thank You to This Episode's Sponsor: Pigment Tracker The Pigment Tracker is a fluorescence spectrophotometer designed to allow cannabis processors and operators a way to quickly, accurately, and cheaply record the pigments in an extract or flower sample. Record keeping allows for more repeatable processing which lowers the likelihood that batches will be rejected by clients or final consumers. Learn More about Pigment Tracker Additional Resources Measuring Heavy Metal Contaminants in Cannabis and Hemp (Paperback version) The Importance of Measuring Heavy Metal Contaminants in Cannabis and Hemp (White paper)The Challenges of Measuring Heavy Metal Contaminants in Cannabis Vaping Aerosols A Conflicting Personality: Can Hyperaccumulating Plants like Cannabis and Hemp be Realistically Used as a Safe Source of Cannabinoids?The Role of ICP-MS in Understanding the Toxicological Link Between Lead Contamination in Cannabis and Hemp Consumer Products and Human Disease Expanding the Panel of Elemental Contaminants in Cannabis and Hemp Consumer Products by ICP-MS: Do You Know the Cost Difference?Heavy Metals in Cannabis and Hemp Education (LinkedIn Group)CannMed ArchiveCannMed Community Board [Facebook Group]Healthcare Provider Medical Cannabis Research Study

ICP-MS and Ion mobility Spectrometry (IMS). Based on book"Analytical Chemistry ", written by G. D. Christian and others

This is Continuation of the chapter-22, Session-1, 2,3.

＜お知らせ＞◆各種イベント：ぜひご参加ください！ ◆９月１０日２１時００分~（Clubhouse 医療部屋クラブ：管理栄養士さんと獣医さんが語る！人と犬猫の栄養！ https://bit.ly/2XKTyEJ ◆９月８日２２時１０分~（Clubhouse ペットのホリスティッククラブ：秋に起こりがちな症状とハーブによるケア） https://bit.ly/3BzpryG ＜当院メルマガ登録先（ココだけの情報！不定期更新）＞ ◆以下のリンク先からご登録ください！ https://forms.gle/sAyQeLYTLtaQwuW98 ＜おススメ配信＞ ◆ himalaya 380. 毛髪ミネラル検査で水銀が高い！珪藻土でデトックスできる？ https://bit.ly/3kYC7Z3 ＜参考ウェブサイト＞ ◆ペットフードに含まれる有害重金属の調査 https://bit.ly/3DTMXsi ◆パラリンピック選手たちからのメッセージ https://bit.ly/3h4LJ3E ◆Clubhouse クラブ【ペットのホリスティックケア】 https://bit.ly/3tXtMbn ◆Clubhouse始めました！ ↓ 探してみてネ ↓ アカウント名：ホリスティック獣医Sara (@holistic_sara) 著書： 【ペットのお悩み解決！メール相談室：犬猫に長生きしてもらうためのホームケア】 ◆電子版（Kindle）：https://amzn.to/3cR7kIa ◆一般（ペーパーバック）：https://amzn.to/2W7C94I ◆質問箱を設置しました！ ペットの健康に関する気になることなど、なにかありましたらお気軽にコメントください。 ラジオ番組内でお答えさせていただきます。 ⇒　https://peing.net/ja/sarapa101mayu Attribution: Otologic, https://otologic.jp Dova syndrome, https://dova-s.jp 往診専門 Saraホリスティックアニマルクリニック DVM(獣医師) / 英国VetLFHom　濱田真由美（Sara） ウェブサイト等: https://linktr.ee/holisticvet.sara Reference: - Analysis of toxic trace metals in pet foods using cryogenic grinding and quantitation by ICP-MS. Spectroscopy 2011; 26(1): 46-68. ーコメント・シェアはお気軽にどうぞー ホリスティック獣医Saraでした

In this episode, host Clint Walker discusses some of the regulatory needs in today's labs, with his guest Pat Steffes, laboratory consultant from Fonebone services. They touch on things Pat finds himself busy with in labs across the country and the direction he sees things going even during the pandemic. If you want to contact Pat for lab consultancy, his email is pat@fonebone.ca. And if you have any questions for Clint regarding ICP-MS or anything Agilent, he can be reached at clint_walker@agilent.com.

Join us for this webinar audio presentation. This presentation is designed for anyone interested in laser ablation that isn't familiar with the technique and would like to identify its advantages and applications of relevance. The following topics will be covered: • What is Laser Ablation ICP-MS • Laser Sources and Selection • Laser Ablation vs Other Analytical Techniques • Fractionation Effects & Application Examples Listeners will leave with an understanding of why labs would utilize laser ablation for elemental analysis and its advantages over aqueous analyses. Listeners will also be introduced to a number of relevant application examples and the ability to ask questions. Lucas Smith, Teledyne CETAC Director of Business Development - Americas will be presenting.

This audio webinar presentation is part 2 of 3 in a series. It was recorded for anyone interested in keeping up with the newest developments in LA-ICP-MS and how it is helping scientists improve their research by pushing the boundaries of what is possible. This presentation will cover the following topics: History of Laser Ablation History of Sample Chamber Designs Development of the Iridia/ Cobalt Cell/ HDIP High Speed Mapping Applications Utilizing New PMI Products Listenerss will leave with an understanding of where this technique began and, more importantly, where the technique is going. We'll discuss applications that are now possible due to the advances and show relevant examples. Dr. Damon Green, Teledyne CETAC VP Technology and Laser Ablation Product Line Manager will be presenting

Enjoy this webinar audio that will provide information on use of carousel type autosamplers with an integrated enclosure for high sensitivity ICP-MS work; benefits include ability to handle low-volume (less than 2mL) samples while preventing sample contamination. These autosamplers can be used as standalone systems or with another accessory such as the Aridus3 Desolvating Nebulizer System. The audio presentation will cover the following information on the ASX-110FR and ASX-112FR Carousel Autosamplers: Autosampler setup, rinse station options and integrated enclosure Autosampler sample rack and vial options Autosampler maintenance and troubleshooting This presentation is designed for: Customers using ICP-MS (quadrupole, magnetic sector, and multicollector types) for trace element detection in semiconductors or isotope ratio measurements in geochemistry. Fred Smith, Teledyne CETAC Product Line Technical Manager for Nebulizer and Enclosure products will be presenting this podcast.

s2e6. In conversation with a family of geologists: Andrey Yu. Bychkov, professor at the Department of Geochemistry, and Yana V. Bychkova, ICP-MS lab manager and head of the Experimental Geochemistry division, both — Lomonosov Moscow State University. Разговор по душам с семьей геологов: Андрей Юрьевич Бычков, д.г.-м.н., профессор кафедры геохимии Геологического ф-та МГУ имени М.В.Ломоносова. Яна Вячеславовна Бычкова, к.г.-м.н., зав. сектором лаборатории экспериментальной геохимии Геологического ф-та МГУ имени М.В.Ломоносова. 01:17 почему собственно геология 04:47 история знакомства в эпоху “гонок на лафетах” и “сухого закона” 10:34 рецепты хороших долгосрочных отношений :) 14:57 почему остались работать в России 20:13 тематика исследований 27:33 про синтез нефти в лаборатории 33:10 про студентов 42:57 мысли о российской науке будущего ResearchGate Яны: https://www.researchgate.net/profile/Ya_Bychkova ResearchGate Андрея: https://www.researchgate.net/profile/Andrey_Bychkov

Today on Mission Supercritical our host Andy Joseph speaks with Rachel Loeber, the Medicinal and Analytical Chemist of LeafLine Labs. Rachel is an analytical chemist by training with experience in chromatography and mass spectrometry. She leads extraction and formulation team. She has served as Symposium Chair for the Minnesota Chromatography Forum for the past six years. She earned her Ph.D. in Medicinal Chemistry in the laboratory of Dr. Natalia Tretyakova at the University of Minnesota – Twin Cities and is well versed in the following techniques: HPLC, LC/MS/M, GC, GC/MS and ICP/MS.

Dr. Lauretta studies the chemistry of planetary materials in our solar system and those around other stars. His research interests focus on the chemistry and mineralogy of asteroids and comets as determined by chemical models of planet formation, in situ laboratory analysis and spacecraft observations. This work is important for constraining the chemistry of the solar nebula, understanding the origin of complex organic molecules in the early solar system, and constraining the chemical inventories of solar and extrasolar terrestrial planets. He is an expert in the analysis of extraterrestrial materials. In particular, he uses inductively coupled plasma-mass spectrometry (ICP-MS), scanning electron microscopy, transmission electron microscopy, electron microprobe analysis, and X-ray diffraction to study meteorites, lunar samples, and particles returned by Stardust. He also operates an experimental laboratory to reproduce mineral assemblages that occur in planetary materials.

By storing and transporting vast amounts of energy derived from solar insolation, the oceans play an important role in shaping Earth’s climate. On the largest scale, ocean currents smooth the temperature gradients between the equator and the poles by redistributing excess energy from the tropics to higher latitudes. Much of this excess heat is transported by the so-called Ocean Conveyor Belt (Broecker, 1991), a global network of ocean currents driven by thermohaline convection. Changes in the pattern and strength of thermohaline circulation affect the redistribution of heat, and thereby significantly influence climate on local to global scales. The reconstruction of paleocurrents has long been a subject of paleoceanographic research. Among the various methods employed in tracing paleocurrents (and modern currents), the Sm-Nd isotope system is experiencing ever increasing attention. First applied in an oceanographic context by O’Nions et al. (1978), it is by now established as a standard tool, as shown by numerous recent publications (e.g. Rutberg et al., 2000; Tütken et al., 2002; Weldeab et al., 2002; Benson et al., 2003; Farmer and Barber, 2003; Piotrowski et al., 2004; Bayon et al., 2002, 2003, 2004; Lacan and Jeandel, 2001, 2004, 2005, and many more). Two lines of application of the Sm-Nd isotope system to oceanography/paleoceanography can be distinguished, both of which were followed for this thesis. The first approach uses the isotopic composition of Sm and Nd hosted in detrital minerals to infer the provenance of terrigenous sediments. This information can be used to draw conclusions about the direction and distance of sediment delivery. The second approach uses the isotopic signature of Nd as a tracer of different water masses. Due to the oceanic residence time of Nd being shorter than the global turnover rate of seawater (500-1000 years vs ~1000 years; Tachikawa et al., 2003), different bodies of water acquire distinct Nd isotopic signatures as a function of the age of adjacent continents. Apart from directly analyzing the Nd isotopic compositions of water samples to trace the modern distribution of different watermasses (e.g. Lacan and Jeandel, 2001, 2004), suitable archives of seawater-derived Nd can be employed to study paleocurrents. Possible archives are fossil remains of marine organisms (e.g. foraminifers; Burton and Vance, 2000), or, most widely used for the recent geological past, Fe-Mn nodules and crusts (e.g. Frank et al., 2002). With slow growth rates on the order of mm/Ma, however, Fe-Mn nodules do not offer the high temporal resolution necessary to study Late Quaternary climate change. Attention has therefore recently turned to authigenic Fe-Mn oxyhydroxides finely dispersed throughout the sediment column (e.g. Rutberg et al., 2000; Bayon et al., 2002, 2003, 2004; Piotrowski et al., 2004). For this thesis, both lines of application of the Sm-Nd isotope system to paleoceanography were followed. The samples were taken from a sediment core collected from the Yermak Plateau in the north-eastern Fram Strait. Situated between Greenland and the Svalbard Archipelago, the Fram Strait is the only deep connection between the Arctic Ocean and, via the Greenland-Iceland-Norwegian (Nordic) Seas, the North Atlantic. The Nordic Seas are an area of deep-water formation important for the global thermohaline circulation. There, the processes of deep-water formation are in a state of equilibrium that is most sensitive to changes in surface water salinity, which, in turn, is strongly influenced by the outflow of water of low salinity from the Arctic Ocean. This makes the history of water exchange between the Atlantic and the Arctic Ocean through the Fram Strait a subject of key interest for climate research. In particular, it was attempted to reconstruct the provenance of sediments deposited on the western Yermak Plateau over the last 129 000 years. This was done by analyzing samples from the sediment core and from potential source areas for their Sm-Nd isotopic compositions. The current understanding is that under present interglacial conditions sediment is delivered to the Yermak Plateau by ice drift from the Siberian shelf areas (Kara- and Laptev Sea) and as suspended load of Atlantic water advected from the south. To resolve these assumed differences in provenance and transport mechanism, the majority of the samples was split into the grain-size fractions clay, fine silt, coarse silt, and sand for Sm-Nd analyses. The position of the investigated core on the upper slope of the western Yermak Plateau limits delivery of sand-size (or coarser) material to ice rafting. The sand fractions of the core samples were therefore interpreted to be exclusively of ice rafted origin, and thus used as an indicator of changes in the pattern of surface currents. Clay- to silt-size material, on the other hand, yields a mixed signal of ice rafting and suspended-load delivery. Based on a comparison of the isotopic compositions of the core samples with those of the samples from potential source areas, a number of conclusions can be drawn: Most core sample show only little isotopic variation between their constituent size fractions (mostly less than analytical uncertainty). Only sand fractions show considerable differences. This can probably be explained by the sand samples’ small sample size relative to their coarse grain size; as a result, most sand fractions probably are not representative. The generally good agreement between the isotopic compositions suggests a common origin of ice rafted detritus (IRD) and suspended load. The possibility of suspended particulate matter transport from the Siberian shelf areas of the Kara- and Laptev Seas to the Yermak Plateau in significant amounts can be excluded. An origin of IRD in the Kara and Laptev Sea is therefore equally unlikely. Instead, a common provenance of IRD and suspended particulate matter from the Svalbard/Barents Sea area is a plausible scenario, supported by isotope-independent data from the literature (e.g. grain-size distribution, mineralogical composition, faunal abundance, etc.). The moderate downcore Nd isotopic variation suggests that, despite repeated large-scale glaciations in the Svalbard/Barents Sea area, the general modern-type circulation in the Fram Strait area has been active for most of the last 129 000 years. The largest deviation from modern conditions is indicated for the peak of the last glacial phase, approximately 20 000 years ago. Then, large amounts of IRD were delivered to the Yermak Plateau by icebergs calving from the Scandinavian ice sheet. Moreover, the occurrence of chalk fragments confirms iceberg drift from as far south as the North Sea. A similar finding has previously been reported for samples from the southern Fram Strait by Spielhagen (1991). Regarding the second analytical approach, i.e. the Nd isotopic analysis of finely dispersed authigenic Fe-Mn oxyhydroxides, implementation of the experimental technique was targeted first. The method of Fe-Mn oxyhydroxide extraction by means of leaching with a mixed reagent (acetic acid and hydroxylamine-hydrochloride) largely is based on the work of Chester and Hughes (1967). Modifications of their method have been reported in Tessier et al. (1979), Chao and Zhou (1983), and Hall et al. (1996), and have recently been compared by Bayon et al. (2002). Based on the experimental protocol described by Bayon et al. (2002), five core samples were processed and analyzed for their rare earth element (REE) concentrations by ICP-MS at the European Union Large Scale Geochemical Facility at the University of Bristol, England, financed by the EU. In addition, nine core samples were processed and the leachates analyzed for their Nd isotopic composition in Munich. The REE patterns of the leachates show an enrichment of the middle REE that is atypical for authigenic Fe-Mn phases. The isotopic analysis also yielded controversial results: downcore, the Nd isotope curves for the leachates and the detrital phases run approximately parallel, suggesting a systematic genetic relationship between the analyzed Nd fractions. A similar relationship appears to exist between data reported in Rutberg (2000), Rutberg et al. (2000), and Piotrowski et al. (2004) for a sediment core from the south-eastern Atlantic. To answer the questions raised by these controversial results, a sequential leaching experiment was designed. Several aliquots of one core sample were treated for different durations with different concentrations of the leaching reagents, and at intermediate steps were analyzed for their Sm-Nd isotopic composition. The results of this leaching experiment point towards a conceptual weakness of the method. In order to avoid contamination by non-authigenic sediment components, all experimental methods described in the literature focus on adjusting the concentration of the hydroxylamine-hydrochloride used to reduce Fe and Mn to their soluble states. This approach, however, does not take into account the dissolution of acid-soluble phases by acetic acid, which in all cases is used at a strength of 4.4 mol·l-1. Consequently, the leaching reagent is sufficiently corrosive to attack easily-soluble detrital minerals and release non-seawater-derived Nd (Hannigan and Sholkovitz, 2001; Dubinin and Strekopytov, 2001). Phosphatic phases are therefore a likely source of nonseawater-derived Nd. Apatite, for instance, is a common component of clastic sedimentary rocks, is easily dissolved by weak acids, and can account for the middle REE enrichment in the leachates. Its high Nd concentrations would mask any seawater signal. To conclude, it appears as though the available extraction techniques are not yet sufficiently refined to reliably determine the Nd isotopic composition of finely dispersed Fe-Mn oxyhydroxides as a proxy for paleoseawater composition.

Trace elements (elements that constitute less than 0.1 wt.% of the analyzed sample) are important tracers for a great variety of processes in many research areas, such as biochemistry, medicine, semi-conductor and nano-technology, environmental science and geosciences (e.g., Anita et al. [2002]; Becker et al. [2004]; Barbante et al. [2004]; Tibi and Heumann [2003]). Accordingly, much scientific effort and financial resources are raised to develop new high-performance analytical techniques and methods for trace element analysis. In geosciences, the capabilities of trace elements analytics have not been used to its full potential because of the complex matrix of the analyzed samples (rocks) and the time consuming procedure to obtain high-quality trace element data by isotope dilution. Accordingly, the aim of this study is to develop of a new, easy-to-use and fast ID-method for the simultaneous determination of many trace elements in geological materials. In addition, the application of this new technique to the analysis of ocean island basalts (OIB) revealed that evolution of geochemical mantle heterogeneities (HIMU, EM-1, EM-2) is far more complex than perviously thought. In the first part of this thesis, a multi-element technique for the simultaneous determination of 12 trace element concentrations in geological materials by combined isotope dilution (ID) sector field inductively coupled plasma mass spectrometry (SF-ICP-MS) following simple sample digestion is presented. The concentrations of additional 14 other trace elements have been obtained using the ID determined elements as internal standards. This method combines the advantages of ID (high precision and accuracy) with those of SF-ICP-MS (multi-element capability, fast sample processing without element separation) and overcomes the most prevailing drawbacks of ICP-MS (matrix effects and drift in sensitivity). Trace element concentration data for the geological reference material BHVO-1 (n = 5) reproduce to within 1-3% RSD with an accuracy of 1-2% relative to respective literature data for ID values and 2-3% for all other values. To test the overall performance of the method the technique has been applied to the analysis of 17 well-characterized geological reference materials from the United States Geological Survey (USGS), the Geological Survey of Japan (GSJ) and the International Association of Geoanalysts (IAG). The sample set also includes the new USGS reference glasses BCR-2G, BHVO-2G, and BIR-1G, as well as the MPI-DING reference glasses KL2-G and ML3B-G and the National Institute of Standards and Technology (NIST) SRM 612. Most data agree within 3-4% with respective literature data. The concentration data of USGS reference glasses agree in most cases with respective data of the original rock powder within the combined standard uncertainty of the method (2-3%), except the U concentration of BIR-1G, which shows a three times higher concentration compared to BIR-1. In the second part of this thesis, this new method is used to determine the trace element concentrations of basaltic samples form the ocean islands St. Helena, Gough and Tristan da Cunha. The results are used to test the validity of established models concerning the trace element systematics of mantle heterogeneities. Since the early 1990's, recycling of altered oceanic crust together with small amounts of 'pelagic' and 'terrigeneous' sediments has become somewhat of a paradigm for explaining the geochemical and isotopic systematics in global OIB. The vastly increased number of data in the literature, in addition to new high-precision trace element data on samples from St. Helena, Gough, and Tristan da Cunha presented here (altogether more than 300 analyses from basalts from 15 key islands), reveals that the trace element systematics in enriched mantle (EM)-type OIB are far more complex than previously thought. In contrast to EM basalts, HIMU (high μ; μ = 238U/204Pb) basalts have remarkably uniform trace element characteristics (systematic depletion in Cs, Rb, Ba, Th, U, Pb, Sr, and enrichment of Nb, Ta relative to La), which are adequately explained by being derived from sources containing subduction-modified oceanic crust. EM-type basalts have La/Th, Rb/Ba, and Rb/K ratios similar to those in HIMU-type OIB, but at the same time, also share some common characteristics that distinguish them from HIMU basalts (e.g., high Rb/La, Ba/La, Th/U, Rb/Sr, low Nb/La, U/Pb, Th/Pb). EM-type OIB also have far more variable very incompatible elements contents (Cs, Rb, Ba, Th, U, Nb, Ta, La) and are less depleted in Pb and Sr than HIMU-type OIB. In addition, each suite of EM-type basalts carries its own specific trace element signature that must ultimately reflect different source compositions. Consequently, although the compositional similarities between HIMU and EM-type basalts suggest that their sources share a common precursor (subducted oceanic crust), their compositional differences can only be explained if EM sources have a more complex evolution and/or contain an additional component compared to HIMU sources. This additional component in EM basalts is likely to originate from a common, although to some degree compositionally heterogeneous, reservoir. Possible candidates are marine sediments; but they do not, at the same time, provide a plausible explanation of the isotopic bimodality in EM-type basalts (EM-1 and EM-2) because the parent/daughter ratios in marine sediments are unimodally distributed. Similar to the bimodal isotopic compositions in EM basalts, the continental crust is composed of two broadly compositionally different parts: the upper and lower continental crust. Relative to the upper continental crust, the lower continental crust is similarly enriched in very incompatible elements, but has systematically lower Rb/Sr, U/Pb, Th/Pb, and higher Th/U ratios. Thus, over time, the upper and lower continental crust evolve along distinct isotopic evolution paths but retain their complex trace element characteristics, similar to what is observed in EM-type basalts worldwide. It is therefore propose here that recycling of oceanic crust together with variable proportions of lower continental crust (scrapped off from the overlying continental crust during subduction at erosive plate margins) and upper continental crust (either in the form of sediments or eroded continental crust) provides a possible explanation for the trace element and isotope systematics in EM-type ocean island basalts.

The Antarctic Peninsula forms part of a magmatic arc at least since Jurassic times. Magmatic dykes are essential elements of such arcs and intrude along zones of instability. In contrast to other hypabyssal intrusions and the effusive products of arc activity, dykes do not only reflect the geochemical characteristics of their magma source but also the tectonic parameters at the time of their emplacement. The South Shetland Islands form an archipelago located at the northern tip of the Antarctic Peninsula and belong to this arc. Areas of up to 100,000 m2 have been mapped at several locations of these islands, mainly on King George and Livingston Island. A structural analysis of the dykes and the host rocks was carried out, and about 250 dykes were sampled for further studies. As deduced from field relationships, on Livingston Island six different intrusive events could be distinguished, on King George Island up to seven. This subdivision into different intrusive events is also well reflected by the geochemical data. Analysis of the structural data of the dykes and their host rocks shows, that the tectonic stress field was not only very similar throughout the archipelago, but that moreover only minor changes of this stress field occurred during the time of dyke emplacement. This holds for all investigated areas in the South Shetland Islands. The geochemical data (ICP-MS) reveal, that most dykes of the South Shetland Islands belong to a calc-alkaline, arc-related suite, ranging from basalts to highly differentiated rhyolites. However, especially during early stages of intrusive activity in the respective areas, also tholeiites occur. Isotopic data (Sr, Nd, Pb) prove a strong crustal component during initial stages of magmatic activity, especially on Hurd Peninsula (Livingston Island). This crustal component decreased with time, accompanied by an increase of sedimentary input into the subduction zone. The high amount of crustal contamination during the initial stages was probably due to a still unstretched continental crust. Besides the continental crust underlying the South Shetland Islands, partial melts from the subducted sediments, fluids derived from the subducting plate and a depleted, heterogeneous mantle wedge contributed to arc magma genesis. According to Ar-Ar datings on plagioclase separates and K-Ar (WR) age determinations, dyke intrusion was restricted to the Paleocene and Eocene. The dykes started to intrude around the Cretaceous/Paleogene boundary at Livingston Island. Only around the Thanetian/Ypresian boundary, dyke intrusion commenced also further NE at Nelson and King George Island, culminating during the Lutetian at 47-45 Ma in all investigated areas. Dyke intrusion then ceased in the latter areas but still continued at Livingston Island until the Priabonian. Combining the information given by the tectonic and geochemical datasets, the time interval covered by the dykes obviously marks a period of geodynamic stability. This includes a stable geometry of the subduction zone and the corresponding parameters (subduction direction and velocity) during that time, as well as stable magma sources. The contribution of the respective sources (sediments, slab, mantle, crust) varied, but the sources themselves remained the same. Very primitive, olivine tholeiitic dykes sampled on Penguin Island as a by-product of this work yielded an unexpectedly high Ar-Ar age (Tortonian), thus questioning the onset of rifting in Bransfield Strait during the Pliocene, as believed so far.

Além da doença de Creutzfeld-Jakob, ìons de cobre tem uma função importante na pathogenese de várias outras doenças neurodegenerativas, por exemplo M. Wilson, M. Alzheimer. Até agora não exisitia nenhuma método para determinar a concentração desde catíon em vivo. Por isso, a minha tése queria achar uma possibilidade para medir cobre por meio de um microscópio ou espetrômetro para seguir a corrente de cobre durante uma depolarisação. O sucesso do uso de corantes fluorescentes para a determinação de concentrações de cálcio nos últimos anos nos encorajou procurar uma substancia que pode detetar especificamente íons de Cu2+. Encontramos que a emissão de TSPP (tetrakis-(4-sulfophenyl)porphine) na região de 645 nm reage muito específico na presença de Cu2+ (KD = 0.43 ± 0.07 µM com pH 7.4). Ela não monstra nenhuma reação com os outros maiores catíons no cérebro, Ca2+ e Mg2+, ao contrário a emissão da maioría das substancias analisadas diminuiu. Também, Zn2+ afeta a fluorescença de TSPP, em outra régião do espétro (605 nm) com uma constante de dissociação KD = 50± 2.5 µM (pH = 7.0). Com TSPP, monstramos primeira vez que existe uma libertação sinaptosomal de cobre depois de depolarisação. Além disso, nós comparamos a quantidade de cobre libertada em camundongos sem (WT) e com (PrP0/0) a deficiência de exprimir o proteina prion (responsável pela doençã de Creutzfeld-Jakob). Achamos a mesma quantidade de vesiculas libertadas em consequência de depolarisação (medido com a corante FM 1-43), mas uma redução significante na quantidade de cobre libertada dos camundongos Prnp0/0. Os resultados foram confirmados de outro método independente, que se chama ICP-MS (inductively-coupled-plasma mass-spectrometry). Com os resultados experimentais, presentamos na tése também uma teoria que pode descrever a função do prion: Assumimos que esta proteína toma o cobre, que sai durante a depolarisação, e leva-o para o interior da célula, não havendo perda. A perda de cobre na ausência do prion seja também uma explicação do processo de CJD.