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Try TrueDark glasses: https://truedark.comTry Danger Coffee: https://dangercoffee.com/Try Suppgrade Labs: https://shopsuppgradelabs.com/Over the last 15 years, I've built companies and spent millions testing what actually upgrades human performance, and I can tell you that mental fatigue has absolutely nothing to do with willpower. In this video, I break down the exact neurochemistry of deep focus. When your brain runs out of dopamine, norepinephrine, and acetylcholine, or gets bogged down by oxidative stress, your executive function collapses. The pharmaceutical industry wants you hooked on expensive stimulants that only treat the symptoms, but the real biological fix is a common antioxidant: Vitamin C.I explain how your brain hoards Vitamin C at levels 100 times higher than your blood, how to bypass the blood-brain barrier using SVCT2 transporters, and why eating sugar before you take it completely blocks its absorption. You'll also learn the exact biohacking stack—including NAC, CoQ10, PQQ, and L-theanine—you need to recycle this molecule, protect your mitochondria, and maintain effortless, razor-sharp focus all day long.Thank you to our sponsors!-KILLSwitch | If you're ready for the best sleep of your life, order now at https://www.switchsupplements.com/and use code DAVE for 20% off-Viome | Check it out at viome.com and use code 10DAVE for 10% off. It's time to stop guessing and start knowing your body.-iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVETimestamps:00:00 – Trailer00:21 – Focus Is Biology01:53 – Brain Chemistry Explained05:33 – Vitamin C Revealed07:09 – How to Dose08:18 – Absorption Barriers09:31 – Optimize Uptake10:00 – Oxidative Stress Problem11:00 – Stack for Deeper FocusConnect with Dave Asprey!Website: https://daveasprey.comTikTok: https://www.tiktok.com/@daveaspreyofficialInstagram: https://www.instagram.com/dave.asprey/Facebook: https://www.facebook.com/Daveaspreyofficial/X: https://x.com/daveaspreyYouTube: https://www.youtube.com/c/daveaspreybprThe Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/Danger Coffee: https://dangercoffee.com/DAVE15Dave Asprey's BEYOND Conference: https://beyondconference.com/Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15Upgrade Labs: https://upgradelabs.com40 Years of Zen: https://40yearsofzen.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Dr. Deb Muth 00:04What if the future of healing isn’t about replacing cells, but about teaching your body how to heal itself again? We keep hearing the words stem cells and exoomes thrown around like they’re interchangeable, but they’re not. One is regulated, controversial, and often misunderstood. The other is rapidly emerging as one of the most exciting communication systems in human biology. Dr. Deb Muth 00:33And here’s the real question no one’s asking. Are we actually regenerating tissue or are we just stimulating the body to remember how it used to heal? Tired of being told your labs are normal, but you still feel terrible? At Serenity Healthcare Center, we don’t chase symptoms. We find the root cause. hormones, gut health, autoimmune conditions, chronic fatigue, brain fog. Dr. Deb Muth 01:02We use cuttingedge functional and regenerative medicine to get you real answers and a real path forward. This isn’t your average doctor’s office. This is medicine the way it was meant to be practiced. You deserve to feel like yourself again. Visit serenityhealthcarecenter.com to book your appointment today. Let us help you heal from the inside out. Dr. Deb Muth 01:28Welcome back to Let’s Talk Wellness Now. I’m Dr. Deb, your host. And if you’ve been following regenerative medicine, you’ve probably noticed the confusion. Patients are asking me every week, are exoomes stem cells? Are stem cells legal in the United States? I heard the FDA is shutting down all these clinics. Can I even get this therapy? Do I have to leave the country for treatment? Today, we’re cutting through the noise. This episode is not hype. Dr. Deb Muth 01:54It’s not sales. It’s education so you can understand the science, the regulatory reality, and the clinical difference between stem cell therapy and exoome therapy. And here’s what I want you to know right up front. Yes, these therapies are being used in the United States every single day. Yes, they’re being offered by highly trained physicians in integrative and regenerative medicine clinics across the country. Dr. Deb Muth 02:22Some are being used in FDA registered clinical trials. Some are being used in observational studies and some are being used in clinical practice under physician discretion. The landscape is nuanced and you deserve to understand it. So, grab your cup of coffee or tea and settle in for a deep dive into the most understood therapies in regenerative medicine. Dr. Deb Muth 02:43what they actually are, how they work, the regulatory landscape, and how they might support your body’s natural healing capacity. Let’s talk wellness now. So, let me start by asking you something. When you hear the word stem cell, what do you picture? Most people imagine damaged tissues magically regenerating or a torn meniscus growing back, cartilage reforming it into an arthritic joint or damaged brain tissue being replaced with healthy new beautiful cells. It’s a beautiful vision. Dr. Deb Muth 03:15And while it’s not quite that simple, the reality is actually more sophisticated and honestly more beautiful. Stem cells are powerful and they absolutely work, but the way they work and the mechanism by which they support healing is far more elegant and more so than most people really understand. And if you’re going to invest in regenerative therapy, you deserve to understand what you’re actually receiving. Dr. Deb Muth 03:44So, let’s start at the beginning. What are stem cells? At their core, stem cells are undifferentiated cells. That means they haven’t yet decided what they want to be when they grow up. Unlike a heart cell or a skin cell or a bone cell which have already committed to a specific function, stem cells exist in this beautiful state of potential. Dr. Deb Muth 04:05They have two remarkable abilities. First, they can self-renew. They can make copies of themselves, maintaining a reserve of these powerful cells throughout your lifetime. Second, they can differentiate under the right conditions. They can transform into specialized cell types. Bone cells, cartilage cells, nerve cells, muscle cells, even blood cells. Dr. Deb Muth 04:27This is why they’ve captured the imagination of the medical world. The potential is extraordinary. Now, there are several types of stem cells and understanding the differences matters tremendously for both understanding how they work and understanding how they’re regulated. Adult mezzenymal stem cells. We call these MSC’s are the most commonly used regenerative medicine. Dr. Deb Muth 04:54These come from bone marrow, atapost tissue, that’s fat, and other adult sources. They’re what we can call multi-potent, meaning they can become several types of cells, but not every type. A bone marrow stem cell isn’t going to become a brain cell, for instance. It has potential but it’s directed potential. Dr. Deb Muth 05:19Then we have perinatal stem cells. These come from umbilical cord blood cord tissue or something called Wharton’s jelly which is the gelatinous substance inside the umbilical cord. These cells are younger, more potent, and research by Weiss and colleagues published in stem cells back in 2006 showed that Wharton’s jelly derived MSC’s have superior proliferation and differentiation potential compared to bone marrow derived cells. Dr. Deb Muth 05:48They’re like comparing a 20-year-old athlete to a 50-year-old athlete. Both can perform, but one has more reserve capacity, more vigor, and more regenerative potential. And this isn’t this is very important because the perinatal sources umbilical cord tissue Wharton’s jelly amniotic tissue these are what many regenerative medicine clinics in the United States are using today and they’re using them because these tissues are incredibly rich in not just stem cells but growth factors cytoines and exoomes. Dr. Deb Muth 06:21Then there are embryionic stem cells. These are pur potent and they become any cell type in the body, but they’re highly regulated, ethically controversial, and honestly, they’re not being used in clinical practice in the United States outside of the very specific FDA approved research trials. Dr. Deb Muth 06:41So, when clinics talk about stem cell therapy, they’re almost never talking about embryionic stem cells. Now, here’s where it gets interesting and this is the part that changes everything about how we understand regenerative medicine. When you receive stem cell therapy, let’s say someone injects umbilical cord derived messenymal stem cells into your arthritic knee, those cells do not typically engraft or become new tissue in any permanent way. Dr. Deb Muth 07:12They don’t set up shop in your joint and start cracking out new cartilage cells for the rest of your life. So what are they actually doing then? Well, in 2011, researchers Arnold Arnold Kaplan and Dennis Korea published a landmark paper in stem cells translational medicine that fundamentally changed how we understand MSC therapy. Dr. Deb Muth 07:35They proposed that we should stop calling memal stem cells and start calling them medicinal signaling cells. Why? Well, because their primary therapeutic benefit doesn’t come from what they become. It comes from what they secrete. Think of stem cells as incredibly sophisticated biological pharmacies. When you inject them into damaged tissue, that arthritic knee, that inflamed autoimmune condition, that injured brain, that don’t just sit there passively, they sense the environment. Dr. Deb Muth 08:07They detect inflammation. They recognize the tissue damage and they understand that the immune dysregulation is present and they see that and respond. They start pumping out hundreds of bioactive molecules, growth factors that tell your cells to repair and rebuild, cytoines that modulate inflammation, chemocines that recruit your body’s own healing cells to the area. Dr. Deb Muth 08:32And these tiny membranes bound packages called extracellular vesicles, including exosomes, which we’re going to talk about extensively today as well. These secreted factors are giving instructions to your native cells. They’re saying, “Let’s reduce inflammation. Let’s modulate your immune response. Let’s promote angioenesis. Dr. Deb Muth 08:53” That’s the formation of new blood vessels, bringing nutrients and oxygen. Let’s stimulate your own resident stem cells to wake up and get to work. Reduce cell death in damaged tissue and restore normal cellular function. This is called paracrine signaling. It’s the cellto cell communication. And this is where the real therapeutic power lives. Dr. Deb Muth 09:14The stem cells themselves, many of them die within days to weeks, but the cascade of healing they trigger, the signals they send, the programs they activate in your own cells, those effects can last for months or even years. Now, this understanding is crucial because it explains why both stem cell therapy and exoo therapy can be effective. Dr. Deb Muth 09:38The stem cells are powerful not because they become new tissue but because of the signals they send and exoomes are those signals isolated and concentrated. The biggest misconception in regenerative medicine is that stem cells replace tissue and in reality they coach healing more than they become healing. They’re biological educators teaching your body to remember how it used to heal before chronic inflammation, toxicity, and disease turned off all those programs. Dr. Deb Muth 10:12So if stem cells don’t exactly end graft and become the new tissue, if their power is in their signaling and then next logical question is why do we need the cells at all? Well, if we could isolate the messengers themselves, what if we could deliver just the communication systems without any of the complexity of the living cells? Well, that’s exactly what exosomes are. Dr. Deb Muth 10:38And they represent the cutting edge of regenerative medicine. So, let me paint you a picture of how cells actually communicate. Because for most medical history, we had it wrong. For decades, textbooks taught us that cells talk to each other in two basic ways. through direct contact like shaking hands or releasing signaling molecules that floated through the extracellular space like messages in bottles, simple chemical messages. Dr. Deb Muth 11:09But in the 1980s and 90s, researchers started discovering something far more sophisticated. cells were releasing these tiny membrane bound packages like a biological FedEx envelope kind of you know it was filled with complex specific cargo and these packages could travel through the blood cross the barriers that normally keep things out like bloodb brain barrier and deliver their contents to distant cells with remarkable precision. Dr. Deb Muth 11:38These are called extracellular vesicles. And exoomes are one of the most therapeutic important types. So what exactly are exosomes? Well, they’re nanosized vesicles, typically 30 to 150 nanome in diameter. To put that into perspective, a human hair is about 100,000 nanometers wide. These are incredible and most impossibly tiny. Dr. Deb Muth 12:09They’re released by virtually all cells in the body, but the most therapeutically interesting exoomes come from mezenymal stem cells. And those medicinal signaling cells we just discussed. And according to a landmark review of Raposo and Stervogal, they published in the journal of cell biology in 2013, exoomes are not cellular debris. They’re not waste products. Dr. Deb Muth 12:35They are precisely engineered communication vesicles or vehicles. Think of them as sophisticated delivery systems carefully packed, carefully labeled, and sent to specific destinations. very specific instructions. Inside each of these exoomes, you’ll find an incredibly sophisticated payload. They are microRNAs. These are small RNA molecules that can literally turn genes off or on in the recipient cells. Dr. Deb Muth 13:06They can tell a cell to start making more collagen, to reduce inflammatory proteins, to activate repair programs that have been shut down by chronic disease for a very long time. There are messenger RNAs, actual templates for protein production. And exoome can deliver these instructions for making healing proteins. There are proteins themselves, growth factors, cytoines, enzymes, all the molecular tools a cell needs to heal. Dr. Deb Muth 13:34And there are lipids, specialized fats that help the exoome membrane fuse with targeted cells, delivering the cargo inside. When an exoome reaches its target cell, it can either fuse the cell membrane and deliver its contents directly inside like a Trojan horse, or it can bind to surface receptors and trigger signaling cascades, setting off a chain reaction of healing responses. Dr. Deb Muth 14:01Either way, it’s delivering very specific targeted instruction. And here’s what makes this so powerful. Those instructions are tailored to what this recipient cell actually needs. So, let me give you some concrete examples of what the research actually shows because this is where it really gets exciting. When researchers inject MSC derived exoomes into hearts that had experienced eskeeia, reprofusion, injury, that’s damaged blood flow being cut off and then being restored. Dr. Deb Muth 14:36Kind of like what happens during a heart attack. Something remarkable happened. A study by Lei and colleagues published in stem cell research in 2010 showed that exoomes significantly reduced the size of the damaged area, reduced inflammatory cytoines that drive tissue destruction and promoted tissue repair signaling. The exoomes were telling the heart cells stop the inflammatory cascade, activate your survival programs and repair the damage. Dr. Deb Muth 15:06In cartilage research, tow and colleagues published work in biioaterials in 2017 showing that exosomes derived from MSC’s could promote cartilage regeneration in osteoarthritis models. And the exoomes carried specific microRNAs that told condondroytes cartilage cells to proliferate and make more extracellular matrix, the structural framework of healthy cartilage. Dr. Deb Muth 15:30for autoimmune conditions. Research by Blazic and colleagues in Frontiers in Immunology in 2014 demonstrated that MSC derived exoomes could shift immune cell behavior from pro pro-inflammatory to regulatory. They could take an overactive self-attacking immune system and restore balance and promote tolerance. And perhaps most exciting brain research, a study by Zinn and colleagues published in the journal of extracellular vesicles in 2013 showed that MSC derived exoomes could cross the bloodb brain barrier. Dr. Deb Muth 16:07That protective shield around your brain that normally keep things out and promote neurological recovery in stroke models. They reduced brain inflammation, promoted neuroplasticity, supported the formation of neural connections, and for mitochondrial dysfunction, which underlies so many chronic conditions, Morrison and colleagues published research and scientific reports in 2017 showing that MSC derived exoomes can actually deliver functional mitochondria or mitochondrial components to damaged cells. They’re not Dr. Deb Muth 16:40just sending instructions, they’re sending spare parts. They’re restoring the cellular powerhouses to produce energy. So why are exoomes fundamentally different from stem cells? Well, exoomes contain no living cells. They can’t replicate. They can’t end graph. And they have virtually no risk of immune rejection or tumor formation. Dr. Deb Muth 17:03Concerns that exist elevate rarely with cellular therapies. They’re essentially biological software updates for your cells. As Fineian Pitiger wrote in their seinal review in stem cells in 2017, MSC derived exoomes represent the active ingredient of stem cell therapy delivered in a cellfree format. That’s the key insight in the in the therapeutic benefit of stem cells and it comes from what they excrete. Dr. Deb Muth 17:33Then exoomes are the secretion isolated, concentrated, and standardized. From a practical clinical standpoint, exoomes offer several compelling advantages. First, consistency. Because exoomes can be isolated, characterized, and standardized, each dose can be remarkably consistent. With living stem cells, there’s variability based on donor age, health status, processing methods, and one batch may be robust, but another might be weaker. Dr. Deb Muth 18:05With exoomes, you can measure the content, measure the potency, and ensure the quality control. Second is storage. Exoomes can be liophalized. They can be freeze-dried and stored at room temperature or refrigerated for extended periods. Stem cells require cryopreserv preservation, careful freezing, careful thawing. They’re fragile. Dr. Deb Muth 18:31Exoomes are remarkably stable. And third, their safety profile. Without living cells, the risk of adverse imunological reactions is dramatically lower. You’re not introducing foreign cells that your immune system might recognize and attack. You’re introducing molecular messages. Fourth is scalability. You can harvest millions, even billions of exoomes from stem cell cultures without ever injecting the cells themselves. Dr. Deb Muth 19:01And you can produce large quantities, standardize them, and make them available to patients. Now, there is a caution here in doing this. The scalability can produce rogue cells, and we want to be cautious of that. So, here’s what I need you to understand. Exoomes don’t force healing. They remind the body how healing works. Dr. Deb Muth 19:24They’re not replacing damaged cells. They’re re-educating the cells you already have. They’re turning back time on the biological programs that got turned off by inflammation, toxicity, trauma, time, and chronic disease. Your body knows how to heal. It’s done its entire life. Every cut that closed, every bone that mended, every infection you fought off, your body orchestrated that healing. Dr. Deb Muth 19:51The problem is that chronic disease, chronic inflammation, toxic exposures, poor nutrition, stress, all of these things disrupt the communication networks that coordinate healing. And exoomes restore that communication. They’re like rebooting a computer that’s frozen. They reset the system and remind it how it’s supposed to function. All right. Dr. Deb Muth 20:14So, this would not be complete if we didn’t talk about regulation because this is where a lot of confusion exists. And I want you to be given a real picture. Not fear-mongering, not pretending. There aren’t regulatory considerations, but the actual practical reality of how regenerative medicine is practiced in the United States today. Dr. Deb Muth 20:38Here’s what you need to understand. The FDA regulates these therapies and they have specific frameworks, but there’s important nuances between regulatory text enforcement priorities and actual clinical practice. And there are also state level regulations that provide additional pathways. The FDA regulates human cells, tissues, and cellular and tissue based products. Dr. Deb Muth 21:05We call them HCT/PPS under two main pathways. Section 361 products are those that meet specific criteria. They’re minimally manipulated, intended for homologous use, meaning these tissues perform the same basic function in the recipient as it did in the donor. They’re not combined with non-tissue components and they’re either autotogus, meaning they come from your own tissue, or they have had minimal systemic effect. Dr. Deb Muth 21:38An example of a clear 361 procedure, your doctor harvests your own bone marrow, we call this PRP, performs minimally processing to or uh perform Yeah. performs minimal processing to concentrate the stem cells through a centriuge and injects it into your arthritic knee the same day. That’s autogus same day but minimally manipulated. Dr. Deb Muth 22:04This is unquestionably legal and is being done in regenerative medicine clinics across the country every single day. So there’s section 351 where products are those that don’t meet all the section 361 criteria. They’re classified as drugs or biologic products and they require FDA approval through clinical trials. Dr. Deb Muth 22:27Now here’s where this gets more nuanced. There are regenerative medicine clinics across the United States using stem cell and exoome therapies in different contexts. First FDA registered clinical trials. These are formal research studies with investigational new drug applications. Patients enroll in trials. They sign informed consents. Dr. Deb Muth 22:48They receive therapies as part of their structured research protocols. And this is completely legal and represents the gold standard for gathering evidence. Second is observational studies and registry programs. Many clinics are collecting systemic data on patient outcomes using these therapies even outside the FDA trials. Dr. Deb Muth 23:12They’re documenting results, tracking safety, and contributing to the growing body of clinical evidence. Third, there’s clinical practice under physician discretion. There are physicians using these therapies based on their own clinical judgment informed consent from patients and their interpretation of the regulatory framework particularly around minimal manipulation and homologous use. Dr. Deb Muth 23:34Now there are also state regulations that provide additional legal frameworks. So, for example, Florida has enacted the Right to Try Act and specific regenerative medicine legislation that allows physicians to offer certain stem cell therapies under the state oversight. Utah has passed similar legislation creating pathways for regenerative medicine products. Dr. Deb Muth 23:57And these state laws recognize that patients should have access to potentially beneficial therapies, particularly when used by trained physicians with appropriate informed consent. The regulatory question often centers around are these products minimally manipulated. Some products clearly are not. They’ve been cultured. Dr. Deb Muth 24:20They’ve been expanded in laboratories and those require FDA approval that they don’t have. The FDA has appropriately shut down clinics using those products. But there are other products that undergo processing that many physicians and manufacturers argue constitutes minimal manipulation. And these tissues are cleared, potentially fragmented or particulated to make them more suitable for injection, preserved using methods like cryopreservation or liophalization and packaged. Dr. Deb Muth 24:54But the cells are not cultured or expanded in the laboratory. The FDA has issued guidance suggesting that many of these processing steps constitute more than manipul minimal manipulation. But many physicians, particularly those who specialized in regenerative medicine for years, disagree with that interpretation and they believe that the processing qualifies as minimal manipulation and that the product should fall under section 361 when used for homologous purposes. Dr. Deb Muth 25:24Is there regulatory debate? Absolutely. The FDA and some clinicians have different interpretations of what constitutes minimal manipulation. But here’s the practical reality. There are hundreds of well-trained, bore certified physicians across the United States offering these therapies every single day. Dr. Deb Muth 25:42They’re doing so based on their understanding of the regulations, their clinical experience, their commitment to patient safety, and their belief that these therapies can help people who have exhausted conventional options. The FDA’s enforcement priorities have focused primarily on the most problematic cases. Clin clinics making blatant disease cure claims, products with documented safety issues, clear cases of cellular expansion and culture, or clinics operating with no medical oversight. Dr. Deb Muth 26:15Reputable regenerative medicine physicians are using products from companies that provide comprehensive documentation of their processing methods. third-party sterility testing, certificates of analysis showing bioactive content, and quality control measures that meet or exceed industry standards. Now, let me be very clear about something. Dr. Deb Muth 26:36Quality matters enormously. Not all stem cells and exoome products are created equal. Research by Burger and colleagues published in the Orthopedic Journal of Sports Medicine in 2021 analyzed 12 commercially available stem cell products and found that many contained zero viable cells, high levels of bacteria, endotoxins and inconsistent growth factor concentrations. Dr. Deb Muth 27:01This is why the company providing these biologic matters tremendously. You want products from manufacturers who provide transport documentation in sourcing and processing. Conduct third-party testing and sterility and potency. Offer certificates of analysis for each batch. Use standardized validated processing protocols. Dr. Deb Muth 27:24Have quality control measures that ensure consistency and don’t make outrageous cure claims or promise. The best regenerative medicine physician carefully vet their suppliers. They don’t use products from companies making unrealistic promises. They use products from manufacturers who are transparent, scientifically rigorous, and committed to quality. Dr. Deb Muth 27:46Now, you specifically ask about homologous use and collagen defects. So, let me address this directly for you. Under the FDA guidance, homologous use means the tissue performs the same basic function in the recipient as in the donor. So for connective tissue, tendons, ligaments, cartilage, fascia, all of that which are collagenrich structures using MSC’s or their derivatives could be considered homologous use. Dr. Deb Muth 28:17MSC’s in their native environment provide structural support to produce extracellular matrix including collagen. Using them to support healing in damaged collagen rich tissues like arthritic joints, torn tendons or degenerative ligaments is arguably the same basic function. So using exoomes derived from MSC’s to support collagen synthesis reduce inflammation and promote tissue healing in the same structures. Dr. Deb Muth 28:46Many practitioners argue this also qualifies as homologous use because you’re supporting the structure and function that MSC’s would naturally support. So here’s the bottom line on the regulatory reality. Regenerative medicine is available in the United States. It’s being offered by highly trained physicians in integrative and regenerative medicine clinics across the country. Dr. Deb Muth 29:11Some therapies are offered in FDA registered clinics and some are offered in observational studies. Some are offered in clinical practice under physician discretion, informed consent, and careful attention to safety. The regulatory landscape is evolving. There are ongoing discussions both federally and state levels about creating clearer pathways for these therapies. Dr. Deb Muth 29:32So, if you choose to go down this road, you want to work with physicians who understand the regulations, who use quality products from reputable manufacturers with rigorous testing and documentation, who are transparent about what they’re using and why, who discuss the current regulatory landscape honestly with you, and who prioritize your safety and truly informed consent above all else. Dr. Deb Muth 29:55This is not a lawless wild wild west. But it is also not as simple as everything is legal and unavailable. It’s a nuanced landscape that requires ethical knowledge. And these practitioners that have this knowledge have got to provide informed patients who understand both the potential benefits and the current regulatory context. Dr. Deb Muth 30:17So let’s have some fun here. Let’s talk about what really matters to you that are listening and that’s what conditions are being supported with these therapies. What does the research show and what are clinicians seeing in actual practice with patients? Because here’s what’s really important. We have both published research evidence and extensive clinical experience. Dr. Deb Muth 30:38And when the two align, that’s when we can feel confident and comfortable about using these approaches. So, let’s start where we have the most substantial evidence. joint health and muscularkeeletal conditions. For arthritis, we have good data. A systemic review by Tan and colleagues published in arthritis research and therapy in 2021 analyzed 20 randomized controlled trials in MSC therapy for knee osteoarthritis. Dr. Deb Muth 31:05They found significant improvements in pain and function particularly in mild to moderate disease. What’s really interesting is when researchers start analyzing whether it was the cells themselves or their secreted factors doing the work. They found that exoomeenriched preparations showed similar benefits to whole cell therapy. Dr. Deb Muth 31:26Now towen colleagues in the biioaterials paper from 2017 demonstrated that MSC derived exoomes could promote cartilage matrix synthesize and reduce inflammation markers. The exoomes carried microarnas that told cartilage cells to make more collagen and proteoglycans, the building blocks of healthy cartilage. Dr. Deb Muth 31:49In clinical practice, physicians are seeing patients with knee, hip, shoulder, and spinal arthritis, experiencing reduced pain, improved function, better motility, and in some cases, measurable improvements in their tissue. I want to share a story here with you because back in 2006, my husband was injured at work. Some of you might have heard me tell this story before. Dr. Deb Muth 32:11Um, he broke two discs in his back and underwent surgery very early on when we started using stem cells. They had put cages and plates in and they used MSC’s to put inside the cage to create a hardened bone so that he could have a fusion and hopefully not have any pain. At the time, what the physician didn’t realize or mistakenly did was he did not put any human bone mixed with these dead cadaavver bone MSC’s. Dr. Deb Muth 32:42And so the MSC’s never grew. They didn’t have anything to grow by. So the plates and the screws just kind of went back and forth for six months before he could see another physician that would look at him differently and understand what actually happened. That was very early on. Today we know so much more than we did before. Dr. Deb Muth 33:01Fast forward to 2014 when my husband was having problems and he couldn’t feel his legs, he couldn’t feel his feet. We decided to undergo uh exoo and stem cell therapy again and we saw a physician in Florida who harvested cells from his bone marrow and his blood and his fat and mixed that all together and then put that back into the back. Dr. Deb Muth 33:27and he had tremendous benefit from it. So, I tell this story because I want you to see the trajectory of how long this has been going on that we’ve been using this and we’re learning as we’re going and things are changing rapidly in this in this world. And so, what we know today and what I’m teaching you today may very well change in a month or six months or a year from now, but we have the foundation at least to understand what is helpful, what is not right now. Dr. Deb Muth 33:54But just be aware that if you’re embarking on exoome or stem cell therapy or MSC’s that you understand that this terrain is going to change. So back to my conversation about what other things can we treat? Well, we can treat tendon and ligament injuries, chronic tennis elbow, Achilles tendonopathy, rotator cuff tears, chronic planter fasciitis. Dr. Deb Muth 34:17These were researched by PA and colleagues in the American Journal of Sports Medicine in 2017 and it showed that bone marrow concentrate injections resulted in improved pain and function compared to steroid injections. Now this mechanism appears to be enhanced collagen remodeling and reduced chronic inflammation. Dr. Deb Muth 34:39These are structural collagenrich tissues using MSC’s or their derivatives for structural support which makes biological sense. It’s homologous use. It’s similar. So clinically we’re seeing athletes, active adults and people with chronic pain who failed physically um failed physical therapy, failed conservative treatments finding relief in this functional uh improvement in this functional world that we live in today. Dr. Deb Muth 35:07So, I want to be clear about what we’re doing here for joint and muscularkeeletal issues. We’re not growing completely new cartilage from scratch or severely destroyed joints. We’re not magically regenerating tissues that’s been gone for decades. That’s not possible here. What you’re doing when you’re using MSSE’s and exoomes is supporting the body’s natural ability to repair, reducing inflam inflammation and damage, and we’re driving progressive degeneration uh or we’re stopping the progressive degeneration. By reducing the Dr. Deb Muth 35:41inflammatory damage, we’re stimulating resonant stem cells that have been dormant. We’re improving blood flow and uh uh oxygen to the tissues like cartilage and tendons. and we’re organizing the body to start creating its own quality collagen as it heals. So, it’s a regenerative support, not a tissue replacement. Dr. Deb Muth 36:07But for many people, this support is lifechanging. So, let’s talk about autoimmune disorders now because this is one of the most exciting and unrecognized applications. autoimmune conditions like rheumatoid arthritis, lupus, MS, Crohn’s disease, ulcerative colitis, Hashimoto’s, they all involve the immune system and the immune system is deregulated. Dr. Deb Muth 36:30And so basically your immune system is seeing this tissue as foreign and it’s attacking it. These MSC’s and their exoomes have profound immune modulatory properties. They don’t suppress the immune system like steroids or imunosuppressive drugs. They modulate it helping to restore balance. So for rheumatoid arthritis, research by Weang and colleagues in stem cells translational medicine in 2016 showed that MSC derived exoomes could shift the balance of immune cells, reducing pro-inflammatory TH7 cells that drive joint disruption uh and increase Dr. Deb Muth 37:08regulatory TE-C cells that maintain immune tolerance. So for MS, a clinical trial by Kasus and colleagues published in archives of neurology back in 2010 evaluated autotogus MSC therapy and MS patients and they found evidence of reduced disease activity, improved neurological function and decreased inflammatory uh lesions on MRI scans. Dr. Deb Muth 37:34The proposed mechanism is MSC’s and their exoomes reduce inflammatory cytoine production promote regulatory imu immune populations support remination of damaged nerves that is rebuilding the protective coating around the nerve fibers and it reduces bloodb brain barrier permeability which prevents immune cells from attacking their brain and spinal cord. Dr. Deb Muth 38:02And so for inflammatory bowel disease, the research by Barnholm uh sorry Barnhorn and colleagues in gut in 2020 showed that MS cell MSC derived extracellular vesicles could support mucosal healing and reduce inflammation in the gut lining. They appeared to restore intestinal barrier function, healing that leaky gut and modulating local immune responses. Dr. Deb Muth 38:30So in clinical practice, physicians are seeing patients with autoimmune conditions, experiencing reduced disease flares, decreasing the need for imunosuppressive medications, improving energy and quality of life, and in some cases extending periods of remission. But here’s what I want you to understand. Dr. Deb Muth 38:52When you see these therapies for autoimmune conditions, we are supporting immune regulation and reducing inflammatory damage. We are not treating or curing the disease in a conventional sense. These therapies work best as part of a comprehensive functional medicine approach that also addresses gut health because 70% of your immune system lives in your gut and environmental triggers like mold, heavy metals, chemical toxins that can drive autoimmune responses, chronic infections that can trigger immune disregulation, stress and nervous system imbalance. And Dr. Deb Muth 39:29these nutritional deficiencies are necessary to help improve the immune function. So regenerative therapy without addressing root causes is like bailing water out of your boat without plugging the hole. You might get temporary relief, but the underlying problem still remains. So let’s talk about neurological conditions. Dr. Deb Muth 39:52And this is where the science gets truly fascinating. for traumatic brain injury and concussion. Research by Zang and colleagues in the Journal of Neurot Trauma in 2015 showed that MSC derived exoomes could reduce brain inflammation, promote neuroplasticity, that’s the brain’s ability to rewire itself and improve cognitive outcomes in animal models. Dr. Deb Muth 40:17The exoomes crossed the bloodb brain barrier, delivered neuroprotective proteins and microRNAs. They reduced inflammation, supported mitochondrial function in injured neurons and promoted both new blood vessels from new blood formation and neurogenesis and the birth of new neurons occurred. Neurological recovery requires a multi-systematic approach. Dr. Deb Muth 40:42Exoomes may support neural repair, but they work best combined with hormone optimization, growth hormone, testosterone, thyroid, pregnnolone, mitochondrial support compounds like NAD, CoQ10, PQQ, carnitine, all of those things that we use traditionally in functional medicine. Now for stroke recovery, there was research by Zinn and colleagues in the journal of extracellular vesicles that showed MSC derived exoomes reduced the size of brain damage and improved neurological recovery in animal models. There was a Dr. Deb Muth 41:19Parkinson’s disease study done by Kimoji and colleagues in the movement disorders in 2018 that suggested that MSSE derived exoomes could support dopamineergic neuron survival and those are the cells that die in Parkinson’s and it can help to reduce neuroinflammation. Clinically, physicians are seeing improvements in patients with postconussion syndrome, chronic traumatic brain injury, early stage cognitive decline, and other neurodeenerative conditions. Dr. Deb Muth 41:52These are not cures, but meaningful improvements in cognitive function, mood, energy, and quality of life. Now, let’s talk about autism spectrum disorder very carefully here because this is a very sensitive but very important topic for families. There have been several clinical trials that have explored MSC therapy for autism. Dr. Deb Muth 42:16Liv and colleagues published research in stem cell translational medicine in 2013 showing improvements in social interaction, communication, and behavioral symptoms in children with ASD who received cord blood MSC’s. Dawson and colleagues in 2017 conducted randomized trial autotogus cord blood infusion and found modest improvements in social communication particularly in children with higher baseline immune dysregulation. Dr. Deb Muth 42:47The proposed mechanisms for modulation of neuroinflammation support the mitochondrial function because many children with autism show evidence of mitochondrial dysfunction, reduction of oxidative stress, improvement in gut brain access dysfunction and modulation of immune dysregulation. In clinical practice, some physicians are seeing improvements in some children, better eye contact, increased language development, reduced sensory sensitivities, improved social engagement, but responses vary significantly, and we cannot predict which children will benefit most. So for Dr. Deb Muth 43:26families considering regenerative approaches for autism, these therapies are supporting the body’s healing mechanisms, reducing neuroinflammation, supporting cellular energy production, modulating immune function. These should only be considered as part of a comprehensive biomedical approach that includes dietary interventions to address food sensitivities, support gut health, environmental toxin removal, particularly heavy metals and chemical exposures, gut healing protocols with targeted probiotics and nutrients, Dr. Deb Muth 44:00metabolic testing and targeted supplementation, and evidence-based on behavioral and developmental therapies. These therapies should only be pursued with practitioners who are honest about what we know and what we don’t know and who follow rigorous safety protocols who never promise cures and who view regenerative medicine as a tool in the comprehensive healing strategy, not a standalone miracle. Dr. Deb Muth 44:26Not only that, these therapies will most likely need to be given several times over the course of this person’s lifetime, possibly even on an annual basis. And this is really important because it is not a oneandone. It is not a one-sizefits-all, and it needs to be looked at as a long-term option for working with autism. So, since we’re looking at stem cells versus exoomes, living cells, with stem cell therapy, you’re receiving living cells that can survive in your body for days to weeks. Dr. Deb Muth 45:02With exoome therapy, there are no living cells, just biological messages they would have sent. So, replication stem cells can potentially replicate. Although therapeutically this happens minimally, exoomes cannot replicate. They deliver the cargo and then they are cleared by your body. With stem cells, it’s primarily paracrine signaling. Dr. Deb Muth 45:28They’re coaching your cells to heal. With exoomes, it’s pure signaling, pure reprogramming your cells without any cellular component. Stem cells as we talked about can be autotogus from your own bone fat, blood or um bone marrow or allergenic from umbilical cord tissue or Wharton’s jelly. Dr. Deb Muth 45:50Exoomes are typically derived from cultured MSC’s often from umbilical cord or bone marrow sources and both can be given by local injection for targeted treatment of joints and tissues and exoomes can be given intravenously for whole body systemic support. both have um low immun immunogicity. I can’t say that word today. Dr. Deb Muth 46:17But exoomes have even lower risk since they contain no cellular material. Now, it’s absolutely critical for you to understand that there are massive quality differences. We’ve talked about this earlier. I want you to be very aware of this and have a conversation with any of the practitioners that you’re considering undergoing this treatment with. Dr. Deb Muth 46:37Here is where it matters more than anything when you’re considering regenerative medicine, the quality of the products and the expertise of the practitioner. Because the reality is not all regenerative medicine products are created equal. We all know that when we take different supplements and not all practitioners understand these therapies at the same depth. Dr. Deb Muth 46:58You want to look for practitioners that are board certified or have some kind of specialized regenerative medicine training. You want to know their clinical experience. How much have they done these procedures? How long have they done this? You want honest communication about the evidence and the limitations in this. Dr. Deb Muth 47:17You want a comprehensive functional medicine approach to go along with these therapies. And you want somebody that’s transparent about their informed consent and their regulatory status. If you have people that are uh claiming that they can cure disease or giving you guarantees, that is not that is not a good practitioner to work with. Dr. Deb Muth 47:37If you have high pressure sales tactics, you need to decide today limited supply for a week. These are marketing manipulations. It’s not medical care. You want to be cautious of extremely low prices because quality regenerative products are expensive to source, process, and test. and store. And if somebody’s offering stem cells or exoomes for a few hundred dollars, seriously, you need to question the quality, the safety, and where they got this from. Dr. Deb Muth 48:09So before undergoing any regenerative therapy, make sure you’re having a very, very lengthy conversation with the person and so you truly understand exactly what you’re getting, how it’s going to be delivered, and what they’re going to do. If there’s one thing I want you to take away from today is that your body has remarkable capacity to heal when given the right biological signals and the right environment. Dr. Deb Muth 48:35Stem cells and exoomes are powerful tools for providing biological signaling that can reduce inflammation, modulate immune function, support tissue repair, and restore cellular communication that’s been disrupted by chronic disease and inflammation. These therapies are available in the United States through trained physicians working in FDA registered trials, observational studies, and clinical practice, and using quality products from manufacturers with rigorous testing and quality control. Dr. Deb Muth 49:04So before you invest in regenerative medicine, do your homework. Ask detailed questions about product quality and source. Verify the products come from reputable manufacturers with certificates of analysis, third-party testing. Work with experienced practitioners. And remember, no injection, no infusion, no biologic can overcome ongoing toxic exposure, chronic stress, poor nutrition, gut dysfunction, and inadequate sleep. Dr. Deb Muth 49:34True healing requires your body and you to actively participate in this healing. If you are unwilling to address the root causes and change the lifestyle factors that disrupted your health in the first place, the biologics can amplify your healing signals, but you have to create the internal environment where healing can actually happen. Dr. Deb Muth 49:56So, I hope this episode has helped you understand regenerative medicine more clearly. Share it with somebody who’s looking for healing beyond the conventional approaches. And until next time, this has been Let’s Talk Wellness Now. Have a blessed day. >> Welcome to Let’s Talk Wellness Now, where we bring expert insights directly to you. Dr. Deb Muth 50:16Please note that the views and information shared by our guests are their own and do not necessarily reflect those of Let’s Talk Wellness Now, its management, or our partners. Each affiliate, sponsor, and partner is an independent entity with its own perspectives. Today’s content is provided forformational and educational purposes only and should not be considered specific advice, whether financial, medical, or legal. Dr. Deb Muth 50:41While we strive to present accurate and useful information, we cannot guarantee its completeness or relevance to your unique circumstances. We encourage you to consult with a qualified professional to address your individual needs. Your use of information from this broadcast is entirely at your own risk. Dr. Deb Muth 51:00By continuing to listen, you agree to indemnify and hold Let’s Talk Wellness Now and its associates harmless from any claims or damages arising from the use of this content. We may update this disclaimer at any time, and changes will take effect immediately upon posting or broadcast. Thank you for tuning in. We hope you find this episode both insightful and thought-provoking. Listener discretion is advised.The post Episode 265 – The Future of Healing: How Exosomes Re-Educate Your Body to Heal Itself first appeared on Let's Talk Wellness Now.

On this episode of Vitality Radio, Jared takes a deep dive into one of the most talked-about tools in the longevity and mitochondrial-health world: methylene blue. You'll learn what it is, how it supports healthy mitochondrial function, why purity matters, and how it may help with focus, mental energy, mood, and healthy aging. Jared also breaks down some new formulations and explains how to stack methylene blue with other nutrients like PQQ, NAD+, creatine, and his own MindFuel formula to optimize clarity, metabolism, and cellular resilience. He shares personal experience using methylene blue for attention challenges and discusses practical ways you can evaluate formulas, experiment safely, and build a personalized stack. Whether you're brand new to methylene blue or looking to refine your regimen, this episode delivers a clear, accessible overview you can immediately put into practice. Protocol Blog PostProduct CollectionBuild your own stack! No code needed, just add to cart for the discount through August 9, 2026.Buy any two from the collection - 20% off Buy three or more from the collection - 30% offVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

In this episode, Dr. Jockers sits down with Dr. Scott Sherr to break down why so many people are stuck in fight or flight and what it's really doing to your brain and body. You'll learn how GABA acts as the "brake system" for your nervous system and why low levels are linked to anxiety, poor sleep, and burnout. They also unpack why fixing stress is not just mental, but deeply biological.   You'll get a clearer picture of what's actually going on inside your cells when you feel exhausted, wired, or mentally foggy. Dr. Sherr explains how your mitochondria play a central role in all of it and why supporting them can change how you feel day to day. They also talk about tools like methylene blue and oxygen therapy, and when they can actually make a difference.   They also get into why constantly pushing harder isn't the answer, and how being able to slow your system down can actually improve your performance. You'll hear what it really means to shift into a parasympathetic state and why so many people struggle to get there. It may change the way you think about stress, recovery, and what your body actually needs.   In This Episode:  00:24 Show Intro and Guest 05:04 Sympathetic Spiral of Doom Explained 08:40 The Parasympathetic Edge 12:32 GABA Gas and Brakes System 15:22 Gut Inflammation and GABA Connection 16:49 Safer Ways to Support GABA 19:55 Alcohol, Benzos and Dependence 22:26 Why Calming Alone Can Backfire 27:13 Mitochondrial Dysfunction Root Causes 30:29 Methylene Blue as an Energy Bridge 32:40 Methylene Blue Controversies 36:20 SSRI Safety Considerations 37:47 High Dose Clinical Use 38:27 Versus CoQ10, PQQ and Creatine 41:29 Hyperbaric Oxygen Basics 43:29 Acute vs Chronic Protocols 46:01 Chamber Pressure Differences 47:17 Health Optimization Medicine Explained 49:55 Trauma and the Sympathetic Loop 55:26 Vagus Nerve Tools and Limits 01:02:54 Performance, Recovery and Closing Insights If you want practical, natural strategies to balance your hormones, heal your gut, boost your energy, and slow aging, don't miss The Dr. Josh Axe Show. Dr. Axe blends ancient wisdom with cutting-edge science and brings on world-class experts for unfiltered conversations you won't hear anywhere else. Transform your health from the inside out and subscribe to The Dr. Josh Axe Show, with new episodes every Monday and Thursday.   Experience faster, more effective health optimization with Troscriptions. Their innovative buccal troche delivery system sends ingredients directly into your bloodstream for rapid results, bypassing the digestive system. Whether you need a boost in energy, immune support, or relaxation, Troscriptions has a solution for you. Visit Troscriptions.com/DrJockers and use the code DRJOCKERS for 10% off your first order.  Most people have no idea how polluted their indoor air actually is. I didn't either until I looked into it. The air inside your home can be significantly worse than outside, which is a big deal when you're spending most of your time indoors. That's why I use Air Doctor. It removes 99.99% of contaminants like dust, mold, smoke, and even viruses, so you're breathing cleaner air every day. You can go to airdoctorpro.com and use the code NUTRITION to get up to $300 off. You'll also get a 30 day money back guarantee and a free 3 year warranty. It's one of the simplest upgrades you can make for your health. If you feel like you need caffeine or nicotine just to get through the day, you're definitely not alone. But there's a better option that doesn't come with the crash or the edge. Ultra Pouches give you clean, steady focus using ingredients like L theanine, Alpha GPC, and B vitamins. No caffeine, no nicotine, just smooth energy that actually feels good. Most people notice better focus, more stable energy, and even an improved mood. If you want to try it out, go to takeultra.com and use the code JOCKERS to get 15% off your order. It's a simple switch that can make a big difference in how you feel day to day.     "Most GABA is made in the brain from glutamate using magnesium and vitamin B6. If you're deficient, your nervous system struggles to slow down."      Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean  TuneIn Radio Resources: Visit takeultra.com and get 15% off with code JOCKERS Visit airdoctorpro.com using code NUTRITION. Visit Troscriptions.com/DrJockers and use the code DRJOCKERS for 10% off.   Connect with Dr. Scott Sherr: Website: https://drscottsherr.com/ Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https:/www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/

Are your relationships stealing your DNA? In this episode, Drs. James and Debra Rouse explore a landmark 2026 study showing that "Social Hasslers" accelerate biological aging by 1.5% annually. Key Discussion Points: The Life-Heist: Understanding how chronic friction frays your telomeres. The Dimmer Switch Metaphor: Why the body enters a defensive Cell Danger Response when you lack social safety. The Rouse 2-Hour Rule: A practical tool to measure your biological recovery time after social interactions. Clinical Resets: The role of peptides like MOTS-c and nutrients like PQQ in repairing mitochondrial damage. The Graceful Withdrawal: Why setting boundaries is a high-level act of biological self-respect.

In Episode 1, I revealed the clues hidden in my labs — the WHY behind my fatigue, slower recovery, reduced power output, dry skin, and metabolic slowdown. Now in Part 3 & Part 4 of my personal case study, we turn insight into ACTION. You'll learn: The ROOT-CAUSE MAP of my body • Low ATP from microbiome imbalance • Fat malabsorption choking metabolism • LPS/endotoxin stress suppressing fat burning • High cortisol blocking thyroid activation • Oxidative stress damaging mitochondria • Genetic vulnerabilities amplifying the effect How this showed up in real life • Running performance dropping • Heart rate spikes in Zone 2 • Needing more fuel on long efforts • Harder time building + maintaining muscle • Skin + hormone changes • Mood and motivation shifts The 4-Phase FutureYou Blueprint™ Plan I built for myself PHASE 1 — Digest • Absorb • Drain PHASE 2 — Kill • Clear • Rebuild PHASE 3 — Mitochondria + Muscle Reboot PHASE 4 — Longevity Optimization I walk you through the WHY behind every tool, including: • TUDCA • Tributyrin (butyrate) • S. boulardii • Phosphatidylcholine • Creatine, CoQ10, PQQ, DHA • Nervous system support • HBOT, sauna, cold exposure This is exactly how I help clients transform from burned-out and metabolically stuck → to energized, strong, and aging powerfully. If you're ready to create your own FutureYou Blueprint™, this episode will show you what's possible when you finally stop guessing — and start investigating.

In this episode, I sit down once again with my most popular guests: Dr. Warren and Dan Schmidt. With over 45 years of clinical experience, Dr. Warren, alongside supplement innovator Dan Schmidt, share the new groundbreaking solutions they have been working on.One of them is a natural testosterone-boosting solution that bypasses injections and risky hormonal shutdown.They also unveil a revolutionary oral delivery method that achieves 85% absorption by activating mucosal uptake. They explain how this delivery system enhances mitochondrial function, boosting energy, hormone levels, and overall well-being.You will also learn about their new Glow topical peptide formula and a complete 24-hour ultimate solution for cellular rejuvenation involving NAD, PQQ, copper peptides, and methylene blue.This brilliant stack supercharges the mitochondria, removes senescent cells, reduces inflammation & oxidative stress, & optimizes sleep.

On this episode of Vitality Radio, Jared takes a deep dive into one of the most talked-about tools in the longevity and mitochondrial-health world: methylene blue. You'll learn what it is, how it supports healthy mitochondrial function, why purity matters, and how it may help with focus, mental energy, mood, and healthy aging. Jared also breaks down some new formulations and explains how to stack methylene blue with other nutrients like PQQ, NAD+, creatine, and his own MindFuel formula to optimize clarity, metabolism, and cellular resilience. He shares personal experience using methylene blue for attention challenges and discusses practical ways you can evaluate formulas, experiment safely, and build a personalized stack. Whether you're brand new to methylene blue or looking to refine your regimen, this episode delivers a clear, accessible overview you can immediately put into practice. Protocol Blog PostProduct CollectionBuild your own stack! No code needed, just add to cart for the discount through December 31, 2025.Buy any two from the collection - 20% off Buy three or more from the collection - 30% offEMUTRIENTS™ Workers Hand & Foot Cream - Vitality Radio POW! Product of the Week 30% off with PROMO CODE: POW20Visit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

In Episode 175 of the Fit Mother Project Podcast, Dr. A talks with neuroscientist and MitoQ Chief Science Officer Dr. Siobhan Mitchell about one of the most powerful — and overlooked — drivers of women's health after 40: mitochondrial function. She shares how her grandmother's Alzheimer's diagnosis inspired her career and why the latest science points to mitochondria, oxidative stress, and “inflammaging” as core players in memory, energy, and healthy aging.You'll learn how exercise, smart intervals, fasting, MCT oils, CoQ10, vitamin C, and mitochondrial-targeted antioxidants like MitoQ can help your cells produce cleaner energy, recover faster, and better protect your brain, heart, and muscles. Dr. Mitchell also breaks down what human studies actually show about MitoQ and other mitochondrial supports like PQQ, NAC, and NAD boosters.If you're a busy mom or midlife woman who wants steady energy, clearer thinking, and stronger training results without burning out your system, this conversation will give you a science-backed roadmap.Key TakeawaysMitochondria = powerhouses and “CEOs” of the cellOxidative stress & “inflammaging” drive faster agingBalance matters: not too much, not too little mitochondrial activityExercise (especially intervals) trains mitochondrial resilienceFasting & ketones trigger autophagy and longevity pathwaysMCTs (especially C8/C10) support ketones and brain functionCoQ10 is essential but poorly delivered into mitochondria via standard supplementsMitoQ = mitochondria-targeted CoQ10 derivative with human dataStudies: better power output, recovery, and less exercise-induced DNA damageVitamin C, magnesium, B12 often need supplement support with ageNAC, PQQ, NAD boosters, and urolithin A: promising but mixed dataNo magic bullets: stack smart supplements on top of fundamentalsMore About MitoQ and Dr. Siobhan MitchellWebsite: https://www.mitoq.com/Use code FITFAMILY at checkout for 10% off your purchaseFacebook: https://www.facebook.com/MitoQ/Instagram: https://www.instagram.com/mitoq/YouTube: https://www.youtube.com/user/MitoQHealthX: https://twitter.com/Mito_QTik Tok: https://www.tiktok.com/@mitoqPodcast: Cell Me About It https://open.spotify.com/show/2Bbc0Oi5ypbui2voVpnCxf?si=40f849b961d041ffDr. Siobhan Mitchell's Email: smitchell@mitoq.comBiographical Information on Dr. Siobhan MitchellDr. Siobhan Mitchell, PhD is the chief scientific officer of MitoQ with over 25 years of research experience in how nutrition impacts brain aging, metabolic health, and longevity. She completed her PhD at SUNY Albany and a post-doctoral fellowship on brain aging at University of Washington.Siobhan held roles at the three largest food companies in the world (Unilever, Nestle and Pepsico), leading trials in Europe, North America and Asia, which investigated the effects of nutrition on cognitive decline, mood and performance. Additionally she was senior director at Noom, where she directed a team...

In Episode 266 of the Fit Father Project Podcast, Dr. A sits down with neuroscientist and MitoQ Chief Science Officer, Dr. Siobhan Mitchell, to unpack one of the deepest levers of health for men over 40: your mitochondria. You'll hear how her grandmother's battle with Alzheimer's led her into decades of research on aging, “inflammaging,” and why mitochondrial function sits at the root of brain health, energy, and longevity.Together, they break down how exercise, fasting, MCT oils, CoQ10, vitamin C, and mitochondrial-targeted antioxidants like MitoQ can make the workouts and nutrition you're already doing more effective. You'll learn what the science actually shows in human trials — from better power output and faster recovery to less exercise-induced DNA damage and improved blood vessel growth in working muscles.If you're a busy man who wants more consistent energy, stronger training results, and better protection for your heart, muscles, and brain as you age, this is an essential listen.Key Takeaways:Mitochondria = powerhouses and “CEOs” of the cellOxidative stress & “inflammaging” drive faster agingBalance matters: not too much, not too little mitochondrial activityExercise (especially intervals) trains mitochondrial resilienceFasting & ketones trigger autophagy and longevity pathwaysMCTs (especially C8/C10) support ketones and brain functionCoQ10 is essential but poorly delivered into mitochondria via standard supplementsMitoQ = mitochondria-targeted CoQ10 derivative with human dataStudies: better power output, recovery, and less exercise-induced DNA damageVitamin C, magnesium, B12 often need supplement support with ageNAC, PQQ, NAD boosters, and urolithin A: promising but mixed dataNo magic bullets: stack smart supplements on top of fundamentalsMore About MitoQ and Dr. Siobhan MitchellWebsite: https://www.mitoq.com/On December 1st, go to https://www.mitoq.com/ for a special Cyber Monday offerAfter December 1st, go to https://www.mitoq.com/ and use code FITFAMILY at checkout for 10% off your purchaseFacebook: https://www.facebook.com/MitoQ/Instagram: https://www.instagram.com/mitoq/YouTube: https://www.youtube.com/user/MitoQHealthX: https://twitter.com/Mito_QTik Tok: https://www.tiktok.com/@mitoqPodcast: Cell Me About It https://open.spotify.com/show/2Bbc0Oi5ypbui2voVpnCxf?si=40f849b961d041ffDr. Siobhan Mitchell's Email: smitchell@mitoq.comBiographical Information on Dr. Siobhan MitchellDr. Siobhan Mitchell, PhD is the chief scientific officer of MitoQ with over 25 years of research experience in how nutrition impacts brain aging, metabolic health, and longevity. She completed her PhD at SUNY Albany and a post-doctoral fellowship on brain aging at University of Washington.Siobhan held roles at the three largest food companies in the world...

Join Dr. Pinkston and her esteemed guest, pharmacist and expert on anti-aging and metabolic health, Jim LaValle, as they dive into the science and benefits of Red Light Therapy, also known as photobiomodulation. They discuss how this non-invasive therapy works by utilizing specific wavelengths of light—ideally in the mid-600s and mid-800s—to stimulate collagen synthesis (for improved skin and anti-aging), boost nitric oxide production (for better circulation), and enhance ATP production (for increased cellular energy and mitochondrial health). LaValle explains how the different wavelengths penetrate tissues, with the shorter waves targeting the skin and the longer, near-infrared waves (800s) penetrating deeper to help with inflammation, muscle soreness, and overall cellular repair. The discussion also covers: Optimal usage (timing and frequency) and best forms (whole-body beds/blankets vs. panels/masks). Potential benefits for conditions like fibromyalgia, post-exercise recovery, and skin issues like psoriasis. Crucial supplements to combine with red light therapy for maximized benefits, including NAD+ boosters (like Nicotinamide Riboside), CoQ10, Magnesium, collagen peptides (with Vitamin C), and Methylene Blue (USP grade). Important warnings, especially regarding photosensitizing medications and pre-existing conditions. New diagnostic tests, like the MeeScreen, for assessing mitochondrial health. Learn how integrating this contemporary tool with foundational nutrition and lifestyle changes can improve longevity, vitality, and help you live The Better Life. See omnystudio.com/listener for privacy information.

5If you've ever wondered why your CoQ10, NAD, or PQQ stack isn't giving you more energy — this episode will change the way you think about fatigue forever. Your mitochondria aren't just little powerhouses. They're safety sensors — constantly asking one question: "Am I safe enough to make energy right now?" In this solo deep-dive, Coach Debbie Potts unpacks the cutting-edge science of the Cell Danger Response (CDR) — based on Dr. Robert Naviaux's research — and why forcing energy production before your cells feel safe can actually make things worse. You'll learn:

Today, Kati welcomes Zac Miner and Dan Schmidt from Best 365 Labs to uncover how optimizing your mitochondrial health can transform energy, skin vitality, and longevity from the inside out. Designed for salon, spa, and med spa professionals, this introductory conversation simplifies the science behind biohacking and reveals why mitochondria—the body's "powerhouse cells"—are the key to improved wellness, recovery, and performance. Learn about groundbreaking supplements like methylene blue, NAD, and PQQ, and discover how enhancing mitochondrial function can elevate both your personal health and your clients' results. Tune in to hear Kati's personal experience, gain actionable insights for your business, and access exclusive offers and links for professionals and consumers in the show notes. TRY THE PRODUCTS| USE CODE KW10  GET A WHOLESALE ACCOUNT WATCH ON YOUTUBE: https://youtu.be/otbv55KOrT8   GET MY BOOK! From First Date to Forever; How to Market Like A Matchmaker: https://joinmya.com/from-first-date-to-forever-book    POWERED BY:  JOIN mya! joinmya.com   FOLLOW BEST 365 LABS Website: https://best365labs.com/?ref=tojxxlga  Instagram: https://www.instagram.com/best365labs    LET'S CONNECT! BTT Instagram: https://www.instagram.com/beyondthetechnique MYA Instagram: https://www.instagram.com/join_mya/    FOLLOW KATI WHITLEDGE Instagram: https://www.instagram.com/katiwhitledge/ Get my favorite bio-hacking products: CLICK HERE   SPONSORS Join the PBA: https://www.probeauty.org/

In this solo episode of The Energy Code, Mike dives into two cutting-edge studies that expand the already impressive profile of Urolithin A, the postbiotic powerhouse derived from pomegranate. The first paper explores how Urolithin A promotes peripheral nerve regeneration via TFEB-mediated mitophagy and suppression of the NLRP3 inflammasome, while the second study—a randomized, placebo-controlled trial in humans—uncovers Urolithin A's ability to rejuvenate the immune system by increasing naive CD8+ T cells, boosting fatty acid oxidation, and reprogramming immune gene expression.   Key topics include: The dual role of Urolithin A in nerve repair: clearing damaged mitochondria & suppressing inflammation Why mitophagy is a linchpin in mitochondrial health, longevity, and disease prevention How TFEB acts as a master switch for cellular detox and mitochondrial renewal New clinical data showing Urolithin A's impact on immune cell function and inflammatory aging Why mitochondrial-targeted compounds (Urolithin A, methylene blue, PQQ, etc.) are foundational to healthspan   Plus, Mike teases the release of two new BioBlue formulations — BioBlue Lite and BioBlue Leuco Lite — featuring a simplified formula of just deuterium-depleted water and pharmaceutical-grade methylene blue or leucomethylene blue.  

Welcome to The Peptide Podcast. If you want to support what we do, head over to our Partners Page. You'll find some amazing brands we trust—and by checking them out, you're helping us keep the podcast going. https://pepties.com/partners/ Before we jump in, I want to quickly address a few comments I have received about the content here. Normally, I wouldn't spend time on something like this, but just for clarity — I have over nine years of formal education, including a Doctorate in Pharmacy, and sixteen years of clinical experience. That includes serving as an adjunct professor at a U.S. pharmacy school and working in oncology and inflammatory disease at a teaching hospital. And yes — for now, you just hear my voice, but that may change. I do plan to incorporate video in the future; I've simply held off because it takes significantly more time to produce, and my priority has been getting the education out to you consistently. Remember, the content is free and meant for education. If it's not for you, that's completely fine — you don't have to listen. It takes a lot of time and energy to put this together, and tuning in is entirely your choice. For my other listeners, thank you for your support and gratitude over the past few years. Now, today we're diving into a compound ATX‑304. It's often referred to as "exercise in a pill". And after we go through the science together you'll see why. We'll cover the back‑story, how it works, how it differs from typical mitochondrial supplements, animal and human data so far, who this may and may not be for — and importantly, what to watch out for.  The Backstory & Why It's Getting Attention ATX-304, was first developed in Sweden by Betagenon AB as a small-molecule AMPK activator designed to mimic the metabolic benefits of exercise and caloric restriction — with the goal of improving obesity, insulin resistance, and overall metabolic health. Early preclinical work in obese and diabetic mice showed impressive results, including better glucose uptake, enhanced fat-burning, improved insulin sensitivity, and even cardiovascular benefits. Human data followed in 2016–2017, where people with type 2 diabetes already on metformin took ATX-304 for about 28 days. Those studies showed reductions in fasting and plasma glucose, improved insulin resistance, and strong safety and tolerability. Today, Betagenon has evolved into Amplifier Therapeutics, and ATX-304 is now in Phase 2 development for metabolic, cardiovascular, and liver-related conditions, with ongoing work to refine oral delivery and broaden its potential uses. What exactly does AMPK do? Think of AMPK as a fuel gauge for your cells. When your cells are running low on energy (like when you haven't eaten, exercised, or your cells are stressed), AMPK turns on. When it's on, it tells the cell to stop storing energy (less fat and cholesterol production), start using energy (burn sugar and fat for fuel), and clean up damaged parts (autophagy, or cellular housekeeping). Basically, AMPK flips the switch from "energy saving" mode to "energy spending" mode, similar to how your body behaves during exercise or fasting. If AMPK is off or underactive, your cells tend to store energy instead of using it, which contributes to weight gain, insulin resistance, and low metabolic activity. So, activating AMPK — like with ATX‑304 — is like giving your body a nudge to burn energy, improve metabolism, and clean up the cells, even without intense exercise. And beyond just turning on AMPK, ATX‑304 also acts as a mild mitochondrial activator, meaning it helps the cell's "power plants" (mitochondria) run more optimally, increasing energy expenditure.  Because of this mechanism, ATX‑304 is sometimes called an "exercise mimetic." Even though it's not a substitute for movement, it triggers many of the same downstream pathways. How It Differs From Mitochondrial "Supplements" There are many supplements out there that claim "boost mitochondria" (e.g., PQQ, CoQ10, NAD precursors). These may support mitochondrial health or function, but typically they don't change the body's energy‑balance set‑point or shift you into a state of enhanced energy usage. ATX‑304, however, directly activates AMPK (the master switch) and supports mitochondrial output — so you get signaling plus hardware improvement. This dual action is what sets ATX‑304 apart.  Also: many mitochondrial supplements lack robust human metabolic‑dysfunction data; ATX‑304 has animal + early human trial data. What About Safety? In human trials (~28 days, T2D patients on metformin) ATX‑304 was safe, well tolerated, lowered fasting plasma glucose and insulin resistance. But because it's still early stage, long‑term safety and outcomes (fat‑loss, muscle preservation beyond short term, cardiovascular endpoints) are not fully proven yet. One of the most exciting things about ATX‑304 is that it encourages the body to burn fat while sparing lean muscle. Because AMPK activation improves muscle glucose uptake and mitochondrial efficiency, your body can preferentially use fat for energy instead of breaking down muscle. Preclinical and early human studies suggest it can reduce fat mass while preserving muscle, which makes it especially interesting for anyone transitioning off GLP‑1 therapies or looking to maintain muscle while losing fat. Practical Dosing in Wellness Context Some peptide clinics use ATX‑304 in doses ranging from 100 to 400 mg a day. It usually comes in 100 mg or 200 mg capsules, and people often take it in the morning to match the body's peak metabolic activity. Cost The last thing I want to discuss is cost. ATX‑304 is currently quite expensive, and there are a few reasons for that. Only a handful of companies manufacture it, so production volumes are small. The synthesis is complex, and the supply chain for key precursors is limited. Since it's still in early development (Phase 2), economies of scale haven't been established yet.  Thanks for listening to The Peptide Podcast.  If you want to support what we do, head over to our Partners Page. You'll find some amazing brands we trust—and by checking them out, you're helping us keep the podcast going. Until next time, be well, and have a happy, healthy week.  

If you're trying to conceive and want to prepare your body naturally, this video is your essential guide to preconception detoxification.

In this episode of The Energy Code, Dr. Mike Belkowski teams up again with Don Bailey, CMO of BioLight, for a fast-paced Q&A session that delves into the essentials of mitochondrial health. Unlike last week's long-form conversation, this episode brings a rapid-fire format — Don poses questions and Dr. Mike answers in 60 seconds or less. The result? A high-energy episode that delivers bite-sized yet powerful insights into how your mitochondria drive energy, longevity, and resilience. From everyday lifestyle choices to cutting-edge supplements like methylene blue, carbon 60, and urolithin B, Dr. Mike breaks down the science of mitochondrial optimization into clear and practical takeaways. Key Topics Covered Mitochondria 101: Why they're called the power plants of the cell and why density matters for energy and health  Quality Control & Renewal: Autophagy and mitophagy as cellular “cleanup crews” clearing zombie mitochondria  Lifestyle Impacts: Sleep, light, grounding, emotional health, and EMF exposure as daily influences on mitochondrial function  Exercise & DNA: Why no single type of workout fits everyone, and how genetic differences shape exercise outcomes  Eating Patterns: Intermittent fasting, time-restricted eating, and the ketogenic diet's link to deuterium depletion   Supplement Spotlight: Methylene Blue & Lueko Methylene Blue: restoring electron flow in mitochondria and synergizing with red light  Carbon 60: a powerful regenerative antioxidant that mitigates oxidative stress  NAD Precursors (NMN/NR): boosting energy efficiency in the electron transport chain  PQQ & Urolithin B: driving mitochondrial biogenesis and clearing out dysfunctional mitochondria  Mushrooms, Shilajit, and synergistic blends in BioBlue's new Fountain of Youth supplement  Big Unknowns: What researchers still don't know about mitochondrial fusion, fission, and their roles in disease  Key Quotes from Dr. Mike “The more energy we produce per cell, the healthier we are. Less energy brings us closer to disease.” “Thoughts and emotions literally shape your mitochondrial health by imprinting on the water in your body.” “Methylene blue can literally restore energy production in a dysfunctional mitochondrion.”   Key Quotes from Don Bailey “I love this rapid-fire style — it keeps us moving from question to question, making it easier to grab key nuggets.” “That's why I talk on speakerphone all the time — I don't want my mitochondria fried by EMFs.” Episode Timeline 00:00 – Welcome & intro to rapid-fire Q&A 11:00 – Why mitochondria matter for health & energy 14:00 – Quality control: autophagy & mitophagy 18:00 – Lifestyle factors: sleep, light, emotions, EMFs 32:00 – Exercise, DNA, and mitochondrial outcomes 34:00 – Fasting, circadian alignment, and deuterium depletion 37:00 – Supplement deep dive: methylene blue, carbon 60, NAD precursors, PQQ, urolithin B, mushrooms, shilajit 56:00 – Big unanswered questions in mitochondrial research 59:00 – Closing reflections and future episode teasers Resources & References Unraveling the role of mitochondrial dynamics in cancer stem cells: Molecular basis and therapeutic implications Dr. Doug Wallace on mitochondrial bioenergetics Dr. Jack Kruse on circadian biology and EMFs BioLight Special: Save 25% when you Subscribe & Save to a BioBundle!For a BioBundle, you choose: 1.) Any one BioBlue supplement(BioBlue, BioBlue (SR), BioBlue Leuco, BioBlue Calm, BioBlue Capsules or BioBlue Leuco Capsules)2.) Any one BioC60 supplement (Regular or Concentrated)   The BioBundle automatically saves you 15% on both of the supplements you choose.You save an additional 10% by choosing to Subscribe & Save to that BioBundle.The 25% savings is passed along for every monthly delivery of your BioBundle!Discount automatically applied at checkout.   Check out the BioBundle by clicking here! Stay Connected Dr. Mike Belkowski: Instagram: @dr.mikebelkowski LinkedIn: Dr. Mike Belkowski Facebook: Mike Belkowski Don Bailey: X: @DonBaileySpeaks BioLight: Website | Instagram | Facebook

#168 - Better Than Botox? 9 Science-Proven Ways to Slow Aging at the Mitochondrial Cellular Level   If your energy is tanked, your skin looks older, and your brain feels like it's buffering—don't blame age, blame your mitochondria. In fact, mitochondrial dysfunction is one of the 12 Hallmarks of Aging.    In this episode of Pretty Well, I'm breaking down how these tiny powerhouses inside your cells control everything from how you age to how well you think, move, and recover. We'll cover 9 evidence-based ways to protect your mitochondria and even boost mitochondrial biogenesis (fancy for “make more of the good stuff”) so that you can slow and even reverse signs of aging. From red light therapy and fasting options to targeted nutrients and why your mitochondria love colorful veggies more than you do—this is the anti-aging roadmap you actually want to follow. No gimmicks, no $400 serums. Just real tools to feel younger, stronger, and sharper from the inside out. Because aging is inevitable—but doing it tired, inflamed, and foggy is not. LInks & Resources: Journal Article: Hallmarks of aging: An expanding universe Carlos López-Otín, Maria A. Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer; Volume 186, Issue 2, 19 January 2023; https://doi.org/10.1016/j.cell.2022.11.001 https://www.sciencedirect.com/science/article/pii/S0092867422013770 Amazon Links:  *As An Amazon Associate I Earn A Small Commission From Qualifying Purchases At No Extra Cost To You*   Mito Red Light Panel: https://amzn.to/4mG3Ax9 Mito Red Light Therapy Glasses - Eye Protection for Red Light (600nm-900nm) - Goggles: https://amzn.to/4oKBiDw HigherDOSE Red Light Therapy Face Mask: https://amzn.to/4ctcIRN Dr. Dennis Gross FaceWare Pro Mask for Anti-Aging, Acne Treatment, and Skin Rejuvenation with Dual Red & Blue Light Therapy: https://amzn.to/42kFWO2    Pure Encapsulations Mitochondria-Supporting Supplements: Mitochondria ATP https://amzn.to/426au7i    NR Longevity https://amzn.to/4cpjsjD    B complex Plus https://amzn.to/4lj1yTD  B complex with PQQ and ALA https://amzn.to/4i3Kv54    CoQ 10 (active form Ubiquinol) https://amzn.to/4lisnHA    Acetyl-L-Carnitine 250 mg https://amzn.to/3G0eBJA Acetyl-L-Carnitine 500 mg https://amzn.to/4jmFxl1    Magnesium Glycinate https://amzn.to/4iWlvhx  Magnesium Citrate https://amzn.to/4ldRPy1    Saccharomyces boulardii (probiotic) https://amzn.to/3DXc4zg    Join the conversation: Share your thoughts with us on social media or in the comments! Subscribe, Share & Review: 

Today, I'm joined by Mike Feldstein, founder of Jaspr (get $400 off this week ONLY) and a true disruptor in the world of clean air and biohacking. If you've ever overlooked just how much the quality of your indoor air affects your sleep, your immune system, and your long-term health, prepare to have your mind changed. CLICK HERE for $400 off your NEW JASPR or use code NAT at checkout. Offer ends 8/8/25. Get my Top 5 Favorite Peptides List FREE click here to download the pdf.   What we discuss: Air scrubbers vs. purifiers ... 00:07:14 Mike's journey and Jasper origins ... 00:08:48 Indoor pollution and wildfire smoke ... 00:14:09 Health impacts from indoor air ... 00:17:16 How air scrubbers work ... 00:18:05 Real-world results and user stories ... 00:20:21 Jasper's sleep and mold studies ... 00:23:36 Wildfires, urban air, and recovery ... 00:30:13 Beyond scrubbers: plants and other tips ... 00:35:44 Microplastics and Jasper's research ... 00:45:55 Filter design and DIY alternatives ... 00:51:25 Kindling Academy & healthy school movement ... 00:56:25 Extending clean air to more schools ... 01:04:43 Jasper discount offer and wrap-up ... 01:11:21   Our Amazing Sponsors: MitoBlue - Everything in the formula is there to help you think clearer, move better, and stay resilient—mentally and physically - Methylene Blue, NMN, PQQ, Apigenin and Ginseng. Go to wizardsciences.com and look for MitoBlue. Use code NAT15 at checkout to get 15% off your purchase. CAROL Bike: With its cutting-edge, science-backed method, CAROL Bike can boost your VO2max by 12% in just 8 weeks—essentially rewinding your fitness clock by a decade. The folks at CAROL Bike are offering a 100-day FREE trial! Visit http://carolbike.pxf.io/Nat or use code NAT100 for a free 100-day trial. OraltidePro  - A unique mouthwash that: Promotes growth of shrinking gums, speeds healing of mouth & tongue, prevents oral infections (such as gingivitis), helps with enamel remineralization, reduces bacteria growth and etching and fills slots in damaged enamel. Check out OraltidePro at profound-health.com and use code NAT15 for 15% off your first order.   More from Nat:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

Today, I'm joined by the brilliant Dr. Vincent Pedre, one of the most sought-after experts in functional medicine and an incredible advocate for what he calls “gut-centric medicine.” Together, we explore how your emotions and beliefs directly impact your gut, why there is no one-size-fits-all approach to gut healing, and the practical steps you can take to support your body's natural balance.   What we discuss: Dr. Pedre's personal and medical background ... 00:06:05 Mind-body connection and overcoming fear through meditation ... 00:09:16 Impact of antibiotics and gut health journey ... 00:18:06 Energy healing, boundaries, and the empath-practitioner challenge ... 00:21:05 Gut-brain connection and integrating mindset in healing ... 00:24:45 Mindset, mantras, and patient transformation ... 00:30:04 Personalizing gut protocols and addressing resistance ... 00:39:03 Tools: intuitive eating, true cravings vs. microbiome-driven urges ... 00:47:45 No one-size-fits-all: diversity and personalized gut diets ... 00:54:08 How the Gut Smart Protocol tailors recommendations ... 00:58:54 Probiotics, spore-based options, and gut support basics ... 01:02:48 Coffee as a gut health microhabit (toxins, plastics, quality) ... 01:06:33 Happy Gut Coffee: rationale, tips, and final takeaways ... 01:09:11   Our Amazing Sponsors: StemRegen - A plant-based supplement protocol designed to enhance stem cell function. support your recovery, flexibility, and long-term vitality. Visit stemregen.co/NAT15 and use code: NAT15 for 15% off your order. Mitolux NEW Second Generation - This second-generation red and near-infrared light therapy panel hits all the marks. Two new wavelengths—810nm and 940nm—target brain performance, deep muscle recovery, and circulation. I use GAMA mode for focus, and Fireplace 2 to wind down. Get a Mitolux BTS2 Sunlamp for 10% off at https://mitolux.com/NAT10, NAT10 will be automatically applied at checkout. MitoBlue - Everything in the formula is there to help you think clearer, move better, and stay resilient—mentally and physically - Methylene Blue, NMN, PQQ, Apigenin and Ginseng. Go to wizardsciences.com and look for MitoBlue. Use code NAT15 at checkout to get 15% off your purchase.   More from Nat:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

In this deeply informative solosode, Dr. Mike Belkowski guides listeners through a comprehensive exploration of mitochondrial function and its profound connection to aging and longevity. Kicking off with a brief reflection on recent guest episodes and a teaser about an upcoming podcast rebrand, Mike then dives into a newly released scientific article from Cell Communication and Signaling titled “Mitochondrial Dysfunction in the Regulation of Aging and Aging-Related Diseases.”   Mike reads and unpacks dense but crucial sections from the paper, including:   The Structure and Function of MitochondriaHe outlines the intricacies of the electron transport chain, supercomplexes, and mitochondrial DNA, emphasizing their roles in energy production, oxidative stress, and aging. Key Cellular Processes Affected by MitochondriaTopics covered include metabolic regulation, calcium and ROS homeostasis, mitochondrial biogenesis, and autophagy, tying them all back to aging and degenerative diseases. Modulating Mitochondrial Function to Slow AgingMike highlights emerging research on mitochondrial nutrients (like CoQ10, alpha-lipoic acid, carnitine), lifestyle interventions (exercise, diet, intermittent fasting), and breakthrough therapies such as mitochondrial transfer and replacement therapies.     He also introduces BioLight's new supplement, BioBlue Fountain of Youth, emphasizing its inclusion of methylene blue or leucomethylene blue, urolithin A, adaptogenic mushrooms, shilajit, and PQQ—all aimed at mitochondrial optimization.   The episode wraps with a powerful message: movement is medicine. Exercise remains the most accessible and potent strategy to boost mitochondrial health naturally. Mike encourages listeners to stay active, get sunlight, engage in red light therapy, and embrace the mitochondrial lifestyle. If you found the information in today's episode particularly interesting and/or compelling, please share it with a family member, friend, colleague and/or anyone that you think could benefit and be illuminated by this knowledge. Sharing is caring :)As always, light up your health! - Key Quotes from Dr. Mike Belkowski: ​​“The mitochondrial space is going to be blown up in the next couple decades for sure… it's going to become a much larger, well-adopted aspect of health and wellness.” ​​“You don't want these dysfunctional cells or these dysfunctional mitochondria to linger around… you want them to be recycled and turned into new, healthy cells.”​“Exercise is the best way to have your endogenous program of mitogenesis running.” - Key points: 00:00 – Introduction: Mitochondrial Focus and Podcast Evolution 02:14 – Podcast Rebrand Announcement & Mitochondrial Mission 03:15 – Review of Article: Mitochondrial Dysfunction in Aging 04:09 – Structure of the Mitochondria: A Deep Dive 06:15 – Electron Transport Chain & Supercomplexes Explained 10:05 – Mitochondrial DNA, Genome, and Gene Expression 11:18 – New BioBlue Supplement Overview and Key Ingredients 14:01 – Mitochondrial Functions: Metabolism, Apoptosis, and Energy 16:29 – Calcium Homeostasis & ROS Generation 20:11 – Antioxidant Defense Systems in Mitochondria 22:15 – Overview of Remaining Sections in the Research Article 25:18 – Targeting Mitochondria to Slow Aging: Introduction 27:13 – Nutrients That Modulate Mitochondrial Function 29:29 – Hormetic Stress, Resilience, and Mitochondrial Biogenesis 31:22 – Calcium Modulators and Mitochondrial Stability 32:01 – Exercise as the Ultimate Mitochondrial Booster 35:03 – Exercise vs. Caloric Restriction in Mitochondrial Health 36:30 – Mitochondria-Supportive Diets and Nutrients 39:12 – Mitochondrial Therapy and Replacement Explained 42:18 – Mitochondrial Replacement for Age-Related Decline 44:17 – Cross-Tissue Mitochondrial Signaling in Aging 45:41 – Translational Research in Mitochondrial Therapeutics 49:08 – Future of Mitochondrial Medicine and Final Thoughts - Save 25% when you Subscribe & Save to a BioBundle!For a BioBundle, you choose: 1.) Any one BioBlue supplement(BioBlue, BioBlue (SR), BioBlue Leuco, BioBlue Calm, BioBlue Capsules or BioBlue Leuco Capsules)2.) Any one BioC60 supplement (Regular or Concentrated)   The BioBundle automatically saves you 15% on both of the supplements you choose. You save an additional 10% by choosing to Subscribe & Save to that BioBundle.   The 25% savings is passed along for every monthly delivery of your BioBundle. No discount code necessary! Discount automatically applied at checkout.   Shop BioBundle by clicking here! - Dr. Mike's #1 recommendations: Water products: Water & Wellness Grounding products: Earthing.com EMF-mitigating products: Somavedic Blue light-blocking glasses: Ra Optics - Stay up-to-date on social media: Dr. Mike Belkowski: Instagram LinkedIn   BioLight: Website Instagram Facebook

What are possible causes for low ejection fraction?Can thyroid function affect ejection fraction?Does levothyroxine affect heart function?How does the functioning of our mitochondria affect heart health?What are your thoughts on CoQ10 and PQQ for heart health?What kinds of exercises are safe to do if your ejection fraction is too low? How long can I fast safely?

Welcome back to the Longevity Podcast! In this episode, I have the pleasure of sitting down with James Strole, a beacon in the radical longevity space and the visionary founder behind People Unlimited and RAADfest. James shares the personal journey that led him into the world of life extension—shaped by a spiritually open-minded mother, a pivotal loss, and a lifelong desire to challenge the idea that aging is inevitable. Get 10% off your tickets to RAADfest using code: "niddam"   What we discuss: James Strole's personal journey to radical longevity ... 00:04:00 Spiritual roots and early inspiration ... 00:10:00 Transition from spiritual to scientific approaches ... 00:13:00 Launching RAADfest and the shift toward hard science ... 00:16:00 Evolution of the longevity movement over the decade ... 00:21:00 Access to longevity innovations and RAAD Clinics ... 00:22:00 Most exciting developments: gene therapy and age reversal ... 00:24:00 Daily longevity pillars: diet, movement, mindset ... 00:26:00 Mindset and embracing the possibility of immortality ... 00:35:00 Overcoming skepticism and “against nature” arguments ... 00:41:00 Societal implications of extreme longevity ... 00:44:00 Are we at the tipping point? The “era of immortality” ... 00:47:00 Advice for newcomers: join the conversation and community ... 00:50:00   Our Amazing Sponsors: NEW Timeline Gummies: Urolithin A supports muscle strength and cellular energy. It's about improving how your body functions at the source. Mitopure is the only clinically proven Urolithin A, giving you six times more than you'd get from a glass of pomegranate juice. Visit Timeline.com/nat20 and use code nat20 for 20% off your purchase. Mitoblue by Wizard Sciences - Everything in the formula is there to help you think clearer, move better, and stay resilient—mentally and physically - Methylene Blue, NMN, PQQ, Apigenin and Ginseng Go to wizardsciences.com and look for MitoBlue. Use code NAT15 at checkout to get 15% off your purchase. Mimio: A supplement that gives you all the cellular, metabolic, and longevity benefits of a prolonged fast—even on the days when you're eating normally. Visit mimiohealth.com/nat and use code NAT FOR 20% off your first single purchase or subscription order.   More from Nat:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

Friends, take a moment for yourself and tune in. Mito2Max is the product all of us should be on. So put your headphones in, sit back and relax and learn how to tap into healthy cellular energy. Both Vicki and Sarah love how they feel when they lean on this product, and they feel you would too.  Ingredients: Coenzyme Q10 Acetyl-L-Carnitine Eriodictyon Californicum Pyrroloquinoline Quinone MetaPWR Metabolic Blend New ingredients focused on healthy metabolic function and cellular energy production have revised an old favorite into a strong addition to the MetaPWR system*. MetaPWR Mito2Max Energy & Stamina Complex is a proprietary formula of standardized plant extracts and metabolic cofactors that support healthy cellular energy production.* Research suggests the ingredients in MetaPWR Mito2Max may improve stamina and decrease fatigue, and support metabolic performance.* New additions like MetaPWR Metabolic Blend, pyrroloquinoline quinone (PQQ), acetyl-L-carnitine (ALC), and coenzyme Q10 can help improve energy and metabolic function like never before.* Studies show the chemical component PQQ in MetaPWR Mito2Max may support mental cognition and memory.* It can also promote mitochondrial biogenesis to support energy production at the cellular level.* According to emerging clinical research, the ALC and coenzyme Q10 in MetaPWR Mito2Max may support energy production, as well as mitochondrial and cardiovascular health.* Delivered in sodium lauryl sulfate–free vegetable capsules, MetaPWR Mito2Max Energy & Stamina Complex has no harmful stimulants and doesn't contain milk, wheat, or animal pMetaPWR Mito2Max promotes energy through healthy mitochondrial function and metabolism.* MetaPWR Mito2Max reduces fatigue and improves physical energy and performance.* MetaPWR Mito2Max supports cognitive abilities, including memory.* MetaPWR Mito2Max may act as an antioxidant and support cardiovascular and  circulatory health.* MetaPWR Mito2Max may assist metabolic adaptation in diveractivities.*   Get the book that was refenced today Good Energy by Dr. Casey Means https://amzn.to/441viwn Get this Book! Link for Essential Emotions book https://amzn.to/3Qd1PJv   Are you ready to release emotions that have been weighing you down? Book a session today! Book with Vicki: https://vickilebrilla.com/coaching Book with Sarah: https://sarahsepos.com/coaching   Vicki's Link- http://referral.doterra.me/1214454 Sarah's Link- https://referral.doterra.me/107766   Get your FREE Sample of VMG (US listeners Only) https://theessentialoilscoop.com/vmgsamples   Scoop of the Day Buy Mito2 Max today and start using it   Do your own research on all of these amazing ingredients and see for yourself why we this this is so amazing!! Coenzyme Q10 Acetyl-L-Carnitine Eriodictyon Californicum Pyrroloquinoline Quinone MetaPWR Metabolic Blend Welcome into our little essential oil world where we talk about the physical and emotional support of our essential oils.   Hi friends, don't forget to leave us a review, your feedback is always welcome, and helps this podcast reach more ears. Join us in our New Facebook Community! Connect on Instagram  We upload a brand new episode every Tuesday and Thursday!   Join our step challenge: https://theessentialoilscoop.com/stepchallenge   Want to learn more about us? theessentialoilscoop.com   Remember to like, share, and subscribe to our podcast so you will be notified every time we upload a brand new episode.  Leave us a review as well, your feedback is always welcome. Also opt-in to our newsletter at theessentialoilscoop.com/news If you have any questions or have subject ideas you would like us to cover please email us at theessentialoilscoop@gmail.com   Tag us on socials using #theessentialoilscoop   Disclaimer:  Welcome to The Essential Oil Scoop Podcast. We want to remind our listeners that the information provided in this podcast is for educational purposes only and should not be considered as a substitute for professional medical advice, diagnosis, or treatment. The use of essential oils is a personal choice and should be done at your own risk. We are not medical professionals and cannot diagnose, treat, or prescribe any medical condition. Please consult with a qualified healthcare provider before using any essential oils or making changes to your healthcare routine. Any information or opinions expressed in this podcast are those of the hosts and guests and do not necessarily reflect the views of any particular organization. Thank you for listening.

Welcome back to the Longevity Podcast! I'm your host, Nathalie Niddam—nutritionist, human potential and epigenetic coach, and I'm excited to share another solo episode with you. Today, I'm diving into a topic that really resonated with my community on Instagram: five essential habits I wish everyone in their 40s (and honestly, any age!) knew to set themselves up for better health and longevity—without spending a dime.   Resources from the episode: • Grounding – The universal anti-inflammatory remedy • Associations between bedtime eating or drinking, sleep duration and wake after sleep onset: findings from the American time use survey • Meal Timing and Anthropometric and Metabolic Outcomes • Meal Timing, Aging, and Metabolic Health • Obstructive sleep apnea and neurodegenerative diseases: A bidirectional relation • Investigation on the Effect of Oral Breathing on Cognitive Activity Using Functional Brain Imaging   What we discuss: Digestive bitters before meals: benefits and how to use ... 00:02:10 Digestive bitters: impact on digestion, absorption, and immune system ... 00:04:01 Digestive bitters: sources, supplements, and usage tips ... 00:08:17 Training your glymphatic system for brain health ... 00:09:12 Tips to support glymphatic drainage: sleep, exercise, hydration, nutrition, sleep position ... 00:10:19 Grounding: definition, science, and health impact ... 00:13:39 How to ground in urban environments; grounding sheets and tools ... 00:17:08 Eating dinner three hours before bed: why and how ... 00:19:02 Early dinner vs. skipping breakfast for metabolic health ... 00:21:36 Circadian rhythm alignment tips and jet lag hacks ... 00:24:05 Nasal breathing vs. mouth breathing: importance and intro to solutions ... 00:24:36 Mouth breathing risks, sleep apnea, and cognitive implications ... 00:26:52 Practical tools and professionals for correcting mouth breathing ... 00:29:12 Summary of the five key longevity tips ... 00:31:59   Our Amazing Sponsors: MitoBlue by Wizard Sciences - Everything in the formula is there to help you think clearer, move better, and stay resilient—mentally and physically—Methylene Blue, NMN, PQQ, Apigenin and Ginseng. Go to wizardsciences.com and look for MitoBlue. Use code NAT15 at checkout to get 15% off your purchase.   More from Nat:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

Today, I'm joined by Cynthia Thurlow, a remarkable nurse practitioner, podcast host, and true hormone whisperer who is on a mission to help women thrive through perimenopause and beyond.   What We Discuss: Perimenopause, menopause, and longevity connection ... 00:06:09 Hormone misunderstandings and HRT discussion ... 00:07:34 Cynthia's clinical experience and women's health ... 00:07:53 Recognizing hormonal imbalances and PCOS in young women ... 00:12:09 Autoimmunity risks and thyroid issues ... 00:19:55 Lifestyle factors: aging, processed food, and alcohol ... 00:24:02 Fasting, digestive rest, and metabolic flexibility ... 00:35:02 Practical fasting tips for different age groups ... 00:36:38 Diet flexibility and protein-forward meals ... 00:41:26 Meal timing, circadian rhythm, and satiety ... 00:56:04 Muscle loss, strength training, and optimal protein ... 01:00:36 Gut microbiome recovery and dietary diversity ... 01:06:15 Creatine: benefits, dosing, and sourcing ... 01:08:36 Where to find Cynthia and her products ... 01:15:30   Thank You To Our Sponsors: Peptide Pro App: can help manage every part of your peptide protocol. From smart scheduling to real-time dose checklists, note taking, and easy calculations. Listeners receive 50% off for the first month. Visit www.peptidepro.app to download the app and use code NATHALIE50 to get started today.  BEAM - These minerals come from humate, a natural substance formed over millions of years as freshwater plants broke down and deposited their nutrients into the soil. Over time, those minerals concentrated into this black, crystalline material that's now one of the most mineral-dense substances on earth. That's what's going into your body—and your cells absorb it within minutes. Visit https://www.beamminerals.com/NAT20 and use code NAT20 for 20% off.  Wizard Sciences - Mitoblue - Everything in the formula is there to help you think clearer, move better, and stay resilient—mentally and physically - Methylene Blue, NMN, PQQ, Apigenin and Ginseng. Go to wizardsciences.com and look for MitoBlue. Use code NAT15 at checkout to get 15% off your purchase.   Learn more from Cynthia Thurlow: Website Twitter Instagram Facebook LinkedIn  Youtube   Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

In this powerhouse solosode, Dr. Mike Belkowski returns to explore the science and strategy behind mitochondrial optimization, building on his foundational framework: the Six Pillars of Mitochondrial Health — energy production, mitochondrial biogenesis, mitophagy, fusion/fission, oxidative stress protection, and the relationship with light. He recaps recent conversations with leading voices in red light therapy and quantum biology, shares exciting details about BioLight's upcoming presence at the Dave Asprey Biohacking Conference, and teases new product launches live at the event. But the heart of the episode centers around the official breakdown of BioBlue: Fountain of Youth — BioLight's most advanced mitochondrial support supplement yet. Dr. Mike walks through each of the seven carefully selected ingredients (Methylene Blue, Urolithin A, Cordyceps, Chaga, Lion's Mane, Shilajit, and PQQ), explaining how they work together to comprehensively support all six pillars of mitochondrial function. Topics Covered: • The Six Pillars of Mitochondrial Health (and why they matter) • BioLight's upcoming events + product sneak peek • Breakdown of each ingredient in BioBlue: Fountain of Youth • Urolithin A, PQQ, and Methylene Blue's role in cellular vitality • The synergy of light, redox, and mitochondrial dynamics Whether you're a biohacker, a longevity enthusiast, or simply someone looking to optimize cellular health, this episode is a masterclass in mitochondrial science and practical supplementation. If you found the information in today's episode particularly interesting and/or compelling, please share it with a family member, friend, colleague and/or anyone that you think could benefit and be illuminated by this knowledge. Sharing is caring :) As always, light up your health! - Key points: 00:00 – Introduction: Mitochondrial Health & Podcast Focus 01:08 – Recent Interviews & Return to the Six Pillars Topic 01:38 – Upcoming Events: Biohacking Conference & Return to Nature Retreat 04:25 – New Product Announcement at Biohacking Conference 07:22 – Health Alchemy Bundle: Over 60 Resources for $50 11:20 – Quick Review of the Six Pillars of Mitochondrial Function 12:13 – Pillar 1: Energy Production (ATP & Biological Water) 12:42 – Pillar 2: Mitochondrial Biogenesis 13:12 – Pillar 3: Mitophagy (Mitochondrial Cleanup) 14:35 – Pillar 4: Mitochondrial Fusion and Fission 15:50 – Pillar 5: Protection from Free Radicals & Oxidative Stress 17:40 – Pillar 6: Relationship with Light & Circadian Health 22:02 – The Supplement That Covers All Six Pillars 23:29 – Fountain of Youth Overview: 7 Ingredients Explained 26:00 – Ingredient 1: Methylene Blue – Energy, Light Synergy, Oxidative Defense 32:13 – Ingredient 2: Bio-Urolithin A – Enhanced Mitophagy & Biogenesis 40:50 – Mushroom Blend: Chaga, Cordyceps, Lion's Mane – Adaptogens for Mitochondria & Brain 49:11 – Ingredient 6: Shilajit – Mineral Density, Energy, and Electron Transport Support 53:39 – Ingredient 7: PQQ – Biogenesis Powerhouse & Antioxidant 57:27 – Recap of All Ingredients & Their Role in the Six Pillars 58:02 – Exclusive Listener Discount 59:41 – Final Thoughts & Call to Action - Get over $6,000 worth of wellness education from top experts for $50!   The Health Alchemy Bundle This is an amazing opportunity put together by Carrie Bennett and Sarah Kleiner! This Bundle is collection of 60+ eBooks, courses, and other resources available for $50 at a mind-blowing 99% discount.    This massive collection of resources is rooted in the science + spirituality of healing with nature, which cover topics like: Circadian & quantum biology Mental, emotional, & spiritual health Nutrition, minerals, & supplementation (when necessary) Herbalism & homeopathy Movement, posture, & fitness Hormonal health, pregnancy, & parenting And even specific issue support—from healing autoimmunity to improving sleep, & more This is a limited opportunity that goes through May 29th, so act now and don't miss out! Get The Health Alchemy Bundle by CLICKING HERE! - Upcoming BioLight Events:   Biohacking Conference - May 28 - 30 (Austin, TX)   Returning to Nature (Quantum Health Retreat), June 26 - 27 (Franklin, TN) - Introducing the Newest BioBlue Supplement! The most comprehensive, powerful mitochondrial support supplement on the market ...   What is The Fountain of Youth in simple terms? An unparalleled supplement for brain power, energy, and longevity This supplement is like a high-performance tune-up for your brain and body. It combines powerful natural and science-backed ingredients to help you think clearer, feel more energized, and support your long-term health.The BioBundle automatically saves you 15% on both of the supplements you choose.   For the next two weeks, SAVE 20% on your order of BioBlue Fountain of Youth! Simply use code FOY20 Code expires 5/29, midnight PST   Click here to check out BioBlue Fountain of Youth - Dr. Mike's #1 recommendations: Water products: Water & Wellness Grounding products: Earthing.com EMF-mitigating products: Somavedic Blue light-blocking glasses: Ra Optics - Stay up-to-date on social media: Dr. Mike Belkowski: Instagram LinkedIn   BioLight: Website Instagram YouTube Facebook

If you've been anywhere near health optimization circles, you already know Ben Greenfield as a NYT bestselling author, former Ironman triathlete, coach, one of the OGs of biohacking. Today, he's my guest on the Longevity podcast.   What we discuss: Ben's new home, cold exposure, and microdosing cryotherapy ... 00:06 Writing, updating, and revising “Boundless” ... 00:09 Key updates: Self-quantification, longevity, new detox protocols ... 00:12 High-tech blood filtration and its impact ... 00:15 Daily detox strategies: Lymphatic movement, sauna, exercise ... 00:17 Ben's evolution: From strict keto to Mediterranean-style eating ... 00:21 Genetics, ancestry, and personalized nutrition lessons ... 00:23 Impact of endurance training, hormone and gut issues, recovery via flexible dieting ... 00:27 Addressing high coronary plaque: Statins, PCSK9 inhibitors, supplementation ... 00:35 Tracking heart health non-invasively (CIMT) ... 00:38 Thoughtful, limited use of pharmaceuticals for health ... 00:44 Peptides: Orals, protocols, favorites (BPC-157, TA1, etc.) ... 00:47 GLP-1 agonists: Powerful but require careful dosing ... 00:51 Biohacks gone wrong: Dosing mishaps and psychedelic stories ... 00:55 Ben's three core tips: Family time, naps, and prayer ... 00:58   Our Amazing Sponsors: Wizard Sciences - Mitoblue Everything in the formula is there to help you think clearer, move better, and stay resilient mentally and physically - Methylene Blue, NMN, PQQ, Apigenin and Ginseng. Go to wizardsciences.com and look for MitoBlue. Use code NAT15 at checkout to get 15% off your purchase.   Mitolux NEW Second Generation - This second-generation red and near-infrared light therapy panel hits all the marks. Two new wavelengths—810nm and 940nm—target brain performance, deep muscle recovery, and circulation. I use GAMA mode when I want to lock in focus, and Fireplace 2 when I want to wind down. Get a Mitolux BTS2 Sunlamp for 10% off at https://mitolux.com/NAT10, NAT10 will be automatically applied at checkout.   LVLUP - Neuro Re-Generate the world's first liposomal triple peptide formula, designed to support mental clarity, focus, and overall brain health. Visit www.lvluphealth.com and use code NAT for 10% off your order.   Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

I'm a 70-year-old woman with hip arthritis. Any recommendations?A treatment on the horizon for high Lipoprotein (a)?After chemotherapy to help shrink a tumor near my husband's spine, he now has numbness and neuropathy in his legsAnother study implicates meat, and now poultry and fish, in causing cardiovascular diseaseWhat do you think of Consumer Lab's recommendations on supplements?I take CoQ10, but I just heard about PQQ. What are your thoughts?

In this episode of Hart2Heart, Dr. Mike Hart breaks down his comprehensive supplement stack, divided into morning, afternoon, pre-workout, and nighttime routines. From neuroprotective agents like saffron and acetyl-L-carnitine to mitochondrial powerhouses like PQQ and CoQ10, each choice is supported by clinical studies and biochemical rationale. Dr. Hart also breaks down how to enhance brain function, support cardiovascular health, improve sleep, and optimize hormonal balance.  Show Notes: (0:00) Welcome back to the Hart2Heart Podcast with Dr. Mike Hart    (0:15) Dr. Hart does a solo covering his supplement stacks (1:00) Morning stack - saffron, alcar, cognitive health (5:00) Major benefits to  nattokinase (8:00) Vitamin k2 benefits (10:30) Fat soluble vitamins - vitamins A,D,E,K (11:40) Autophagy and anti-aging - spermidine and supplement timing (13:00) Beta-Alanine - performance and dosing strategy (14:00) Afternoon stack - zinc, boron, and testosterone balance (21:00) Vitamin D & synergistic support (22:30) Pre-workout stack - creatine, citrulline, beta-alanine, and HMB (26:00) Nighttime stack - sleep optimization with magnesium and apigenin (30:00) Fish oil: heart, brain, and REM sleep benefits --- Dr. Mike Hart is a Cannabis Physician and Lifestyle Strategist. In April 2014, Dr. Hart became the first physician in London, Ontario to open a cannabis clinic. While Dr. Hart continues to treat patients at his clinic, his primary focus has shifted to correcting the medical cannabis educational gap that exists in the medical community.  Connect on social with Dr. Mike Hart: Social Links: Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart

150 - What If Your Brain Fog Isn't All In Your Head? 7 Fixes You've Never TriedIf you've ever walked into a room and immediately forgotten why you're there, you'll want to hear this. What if your brain fog isn't just a coffee shortage… but a mitochondrial meltdown? In this episode of the Pretty Well Podcast, we're digging into the real root of brain health—your mitochondria. Yep, those tiny powerhouses are pulling more weight than you think. You'll learn 7 simple, science-backed ways to boost your brain clarity, energy, and focus (without adding 42 more supplements to your cart). If you're dealing with forgetfulness, low energy, or feeling like your brain's operating on dial-up, this one's for you. We're talking longevity, cognitive vitality, and how to keep your brain as sharp as your wit. Think of it as a tune-up for your brain; real ways to support long-term cognitive health so you can stay sharp, focused, and actually remember where you put your keys.Links & Resources:Atorvastatin decreases the coenzyme Q10 level in the blood of patients at risk for cardiovascular disease and stroke; Arch Neurol. 2004;61(6):889-892. doi:10.1001/archneur.61.6.889https://jamanetwork.com/journals/jamaneurology/fullarticle/786017#google_vignetteEffects of Coenzyme Q10 on Statin‐Induced Myopathy: An Updated Meta‐Analysis of Randomized Controlled Trials; Journal of the American Heart AssociationVolume 7, Number 19 https://doi.org/10.1161/JAHA.118.009835 Amazon Links: *As An Amazon Associate I Earn A Small Commission From Qualifying Purchases At No Extra Cost To You*Pure Encapsulations Brand Mitochondria-Supporting Supplements:Magnesium Glycinate https://amzn.to/4iWlvhx Magnesium Citrate https://amzn.to/4ldRPy1 B complex Plus https://amzn.to/4lj1yTD B complex with PQQ and ALA https://amzn.to/4i3Kv54 CoQ 10 (active form Ubiquinol) https://amzn.to/4lisnHA Saccharomyces boulardii (probiotic) https://amzn.to/3DXc4zg Bellway Super Fiber: https://amzn.to/4i7Ud6B Nature's Sunshine Liquid Chlorophyll ES: https://amzn.to/42xQEly Epic Water Filter Products: https://amzn.to/42wOKSe Join the conversation: Share your thoughts with us on social media or in the comments!Subscribe, Share & Review: Remember to subscribe, share this episode, and leave a review. Your support helps us reach more women looking for answers.Disclaimer: Nothing in this podcast is to be taken as medical advice, please take informed accountability and speak to your provider before making changes to your health routine.The primary purpose of The Pretty Well Podcast being to educate. This content is for informational and educational purposes only. It is not intended to provide medical advice nor to take the place of such advice or treatment from a personal physician. By listening to this content, you agree to consult your own physician or qualified health professional regarding specific health questions. Neither Lisa Smith, The Pretty Well Podcast, nor any guest takes responsibility for possible health consequences of any person or persons following the information in this educational content. All listeners of this content, especially those who are pregnant or taking prescription or over-the-counter medications, should consult their physicians before beginning any nutrition, supplement, or lifestyle program. The Pretty Well Podcast is for private non-commercial use and our guests do not necessarily reflect any agency, organization, or company that they work for. In addition, opinions of interview guests do not necessarily reflect the opinions of Lisa Smith and/or The Pretty Well Podcast. This content is not guaranteed to be correct, complete, or up to date.If you tune into any of the following shows, you'll like ours too! The Dr. Josh Axe Show, Wellness Mama, Be Well By Kelly Leveque, The Freely Rooted Podcast with Kori Meloy, The Dr. Mark Hyman Show, Dr. Jockers Functional Nutrition

你更年期了嗎，沒有不用太得意，只是遲早的問題啊～（冷笑）

Men's health is in serious decline — and it's happening faster than most realize. In this episode, CJ breaks down the alarming trends and gives you practical, science-backed steps to reclaim your health and vitality.Globally, men are living 5 years shorter than women. Testosterone levels are plummeting by 1% every year, sperm counts have dropped by over 50% in 40 years, and chronic diseases like obesity and diabetes are hitting earlier than ever. In regions like the UAE, 7 out of 10 men under 30 are already facing obesity and diabetes risks.But here's the good news: your body wants to heal. By giving it the right inputs, you can dramatically shift your health trajectory.What's Going Wrong:Stress & Poor Sleep suppress testosterone and increase cortisol.Processed food & toxins disrupt hormones and damage mitochondria.Low testosterone leads to fatigue, mood swings, weight gain, and fertility problems.Chronic inflammation silently fuels disease.Poor gut health undermines immunity and hormone balance.Toxin buildup from everyday products mimics hormones and throws off your system.Neglecting mental health quietly destroys resilience and well-being.What You Can Do About It:Prioritize Sleep: Poor sleep drops testosterone by 15% in just one week. Stick to sleep protocols and build a healthy nighttime routine.Manage Stress Daily: Meditation, breathwork, evening walks, or even watching the sunset can lower cortisol and protect your hormones.Exercise Regularly: Strength training 3–4 times a week boosts testosterone and supports mitochondrial health.Support Mitochondria & Gut Health: Take supplements like CoQ10, PQQ, and Acetyl L-Carnitine. Add probiotics, prebiotics, and digestive enzymes for a healthier gut.Detox & Boost Cardiovascular Health: Sweat daily (exercise or sauna), eat cruciferous vegetables, and increase nitric oxide with beetroot or leafy greens. Consider supplements like L-arginine or L-citrulline.Key Takeaways:Men's health is an ecosystem — hormones, gut, mitochondria, and mind are deeply connected.Tiny changes create momentum. Stack small habits daily.Movement matters — even non-exercise activity boosts nitric oxide and heart health.Supplements are helpful but not a shortcut. Lifestyle comes first.Your health is your highest ROI. There is no wealth without health.Your action starts today. Share this episode with someone who needs it — and if you're a woman, this knowledge is just as powerful for supporting the men in your life.Stay strong. Keep biohacking.

An episode from The Holistic Navigator. This is not to diagnosis or treat any disease/illness. Consult your physician before taking supplements or medications OR before you stop taking medications. This is for entertainment/informational purposes only! When it comes to supplementation, the amount of choices can be overwhelming. Even with the standard nutrients that most folks are familiar with, research is constantly changing and new products emerge frequently. That's why we're here. We stay on the forefront of the supplementation industry and are always on the lookout for the most effective, trustworthy supplements out there. On this week's episode Ed discusses a few of his favorites that you might not be familiar with. From bone health, to fighting pain and inflammation, to a powerful antioxidant that can help in many ways, these are supplements that pack a punch. Admittedly, these are nutrients that even we had to do a little brushing up on, but now we're looking at them with more discerning eyes and are happy we did. We hope you enjoy this episode! Some Topics We Discussed: What are the 3 supplements you've probably never heard of that can make a drastic difference in your health ?(4:20) How does VItamin K help us and why should we take it? (7:50) What is SPM and why should we consider it? (14:52) What is PQQ and why would we want it in our supplement toolkit? (20:35) What damages our mitochondria? (23:08) Key Takeaways From This Episode: Conventional practitioners are not going to get training on natural remedies unless they choose to spend their time learning about it on their own. (4:25) Some researchers are now saying that Vitamin K may even be more important than Vitamin D. (8:44) When you take Vitamin K, make sure you take it with fat. (14:44) SPMs have a unique way of dealing with inflammation in ways that curcumin and omega-3s don't do. (18:37) PQQ helps address mitochondrial function. (22:55) ZenCast.fm

On today's episode of The Wholesome Fertility Podcast, I am joined by Dr. Nayan Patel @aurowellness, a pharmacist, researcher, and glutathione expert, to explore the critical role glutathione plays in fertility and overall health. Dr. Patel shares his journey from traditional pharmacy to developing a breakthrough delivery system for glutathione through the skin, and why this antioxidant is essential for protecting egg and sperm quality. In this episode, you'll learn how oxidative stress impacts fertility, why diet alone might not be enough, and how his innovative technology can support the body's natural detoxification process. Be sure to tune in for this fascinating conversation packed with practical advice and insights for anyone on the fertility journey! Key Takeaways:  Glutathione is the body's most abundant and powerful antioxidant. It plays a vital role in protecting reproductive health by reducing oxidative stress. Most oral supplements don't get absorbed effectively, making Dr. Patel's skin-delivery innovation a game-changer. A healthy lifestyle and cysteine-rich foods are essential for maintaining glutathione levels. Guest Bio: Dr. Nayan Patel @aurowellness is a highly sought-after pharmacist, wellness expert, and thought leader in his industry. Since 1999, he has collaborated with physicians to custom-develop medications and design patient-specific drug and nutrition regimens. As the pharmacist of choice for celebrities, CEOs, and physicians alike, Dr. Patel is recognized for his innovative approach to health and wellness. He is the author of The Glutathione Revolution: Fight Disease, Slow Aging & Increase Energy, which distills over a decade of clinical research on the master antioxidant, glutathione. His patented technology for delivering glutathione topically has revolutionized how the body absorbs this essential molecule. From this breakthrough, he also created the Auro GSH Antioxidant Delivery System, a skincare line designed to deliver antioxidants more efficiently and effectively than ever before. Websites/Social Media Links: Learn more about Dr. Patel's Products Follow Dr. Patel on Facebook For more information about Michelle, visit www.michelleoravitz.com  To learn more about ancient wisdom and fertility, you can get Michelle's book at: https://www.michelleoravitz.com/thewayoffertility  The Wholesome Fertility facebook group is where you can find free resources and support: https://www.facebook.com/groups/2149554308396504/  Instagram: @thewholesomelotusfertility Facebook: https://www.facebook.com/thewholesomelotus/ ------------------------------- Transcript: # TWF: Dr. Nayan Patel [00:00:00] [00:01:00]    **Michelle Oravitz:** So welcome to the podcast, Dr. Patel. **Dr. Nayan Patel:** Well, thank you for having me. I appreciate the time today. **Michelle Oravitz:** Yes, I'm very excited to talk about what we are going to discuss, which is glutathione. But before we get to that, I would love to get your backstory and how you got into the work that you're doing today. **Dr. Nayan Patel:** Oh my god, absolutely. So start off as a pharmacist, as a career as a pharmacist, and after graduation [00:02:00] from pharmacy school. In Southern California, we were, we were trained to take care of the patient's needs and medications. And very quickly I realized that the medications we have at that time were actually not solving any problem. They were just maintaining people's problems. And very, very early on, you know, you have an aha moment in your life. That oh my god, what what did I just do right? Oh, I'm just not solving any problems So I had to turn my career to a completely different angle no former educations in in making medications or doing compounding or customizing medications that dive into the that practice and 25 years later here we are today and looking back at that and said, what a journey, what a turning point I had, because it shaped me for who I am today. I had the privilege of making medications and design treatment plans and drug plans for so many individuals helping them in their health and wellness journey. And then all [00:03:00] roads led to me to a discovery of a novel technology that can deliver glutathione. And it all started because I was just curious to find out how we can help people solve their own problems instead of trying to figure out medications to solve the problems. Right? Even though glutathione is not a, it's, it's something that body produces internally we're using it as a supplement today, but. And overall my goal was not to do anything and just enhance the body's own ability to to defend itself. And so here we are today it's a very interesting career for me for sure. **Michelle Oravitz:** For  sure. And first of all, just for people listening that don't really know much about glutathione, I'd love for you to share really what it is and also why it could be so challenging to supplement with. **Dr. Nayan Patel:** Absolutely. so the glutathione in a nutshell Is three amino acids coming together in a single chain. It's a one of the smallest form of peptides we have You two amino acid chains, three amino [00:04:00] acid chains, four, five, 30, 40, 50, and thousands of the chains as well. The simplest form, of course, is glutathione, which is about three amino acids coming together. It's by far the most abundant molecule produced in the human body. And if that's produced so much, we ought to know what it's supposed to do for us. And so that's what my research came back for 140 years that we have known about glutathione. Nobody's ever figured out how to actually get inside your body. And so, 60 years ago, 70 years ago, we had a medication approved by FDA to enhance glutathione level. And as of today, that is the only medication that has been approved ever. In the whole, in the whole world, which is N acetylcysteine, which is one of the amino acids that's been used to produce chlorothione. And that's the only thing that has been available for the last 60, 70 years. **Michelle Oravitz:** So let's talk about what so we definitely, that's one of the things that um, I've been doing for egg health and also sperm [00:05:00] quality, cause it's such a high potent antioxidant. And one of the things that I have always suggested is N acetylcysteine because that's the precursor and we knew that that was like the one way that the body was able to produce it. Okay. Thank you. But then there were some supplements that still supplement with glutathione, liposomal, like different ways, which I know are not really shelf stable. So there's always been challenges with that, but before we continue on with that, I'd love for people to hear, like, what glutathione can benefit, how it can benefit the body. **Dr. Nayan Patel:** So, I understand your audience is interested more in the fertility side of the whole thing. So, you're dealing with rather younger individuals overall which is a good sign because younger patients have, everything at their disposal for the body to respond to even the smallest amount of nutrients that they receive. If the same amount of nutrients is given to an 85 year old person, they're not [00:06:00] going to feel anything, right? But if 20 year old person gets a small amount of good nutrition, they respond very, very well. And so I want to make sure that people understand that **Michelle Oravitz:** And also just to kind of mention um, sometimes we have 40 year olds too, that are trying to conceive or like trying to do IVF. So just kind of like, yeah, the whole, **Dr. Nayan Patel:** They're still spring chicken to **Michelle Oravitz:** okay. Okay. It's good for them to hear that. **Dr. Nayan Patel:** I mean, I've helped people in the very, I mean, in the late forties to get babies as well. So it's not something that's not doable. It's just gets incredibly hard after the age of 40. So it's, not that easy to do so, but the glutathione has multiple properties and understanding what glutathione does is, monument in over. in our therapies because with the two things that we do know is it's the ability for glutathione as an antioxidant to detoxify, neutralize all the free radicals in your body. But the second component is also help you detoxify by conjugating [00:07:00] inside your liver with metabolites and chemicals binding to them. So we can basically get rid of it from from your body. So the two functions that we do know That exists today. There's a lot more research still existing that we need to do. So we, we still are urging researchers to go back and use this new technology product and see if we can find out more things that glutathione can do for us. So one two the sperm or the egg quality is dependent on how your body is able to neutralize those free radicals. Those free radicals are actually toxic to all the embryonic membranes and embryos itself and the quality of the sperm and the egg itself. And neutralizing those free radical of body, there's three ways to do that part. One, you take outside products like vitamin C, and vitamin E, and CoQ10, and and C60s, and I mean, methylene blues, I mean, there's a slew of products that says, oh, we are so called antioxidants, right? So that's [00:08:00] category one. The category two of the products are produced endogenously inside your body are enzymes like catalase, supra oxide, puase, SOD, for short glutathione peroxidase, or GPX for short. So these are the enzymes that the body produces to deal with the oxidative stress or the free radicals. Okay, so those are the category one are the category two. The third category is only one product, which is glutathione. And if you look at it, the body produces so much of glutathione, and the effects of glutathione is so powerful, that if you combine the category one, which is all the antioxidants from outside sources, and the enzymes that your body produces, those two combine, Glutathione can surpass the antioxidant properties. And so I want listeners to understand very carefully is that the glutathione needs to be a basic cornerstone in everybody's arsenal. Every medicine chest in the world should have a [00:09:00] bottle says glutathione And in that bottle either you have a product or it have a note saying that eat healthy food to Let your body produce its own glutathione Either way that note has to be there on every medicine chest out there and you're right There's so much noise out there I want to cut to the noise today because if you just put your favorite search engine or your ai robot is going to tell you hey glirathion, there are a thousand different products out there. Choose one You Right. And as a consumer it's very hard to find out what to choose correctly and people hide behind a great technologies that that exists in the world and said, Oh, my, my product uses this technology. So it's the best one in the world. And you mentioned liposome technology, by the way, I just will let, you know, we were one of the very first few people that actually use liposome to produce the first liposomal glutathione. This was 25 plus years ago, right? And we made the liposome because at that time that was the [00:10:00] best technology that existed in the pharmaceutical world. And the doctor that owned the patents for those came to me and said, Hey, we've been very successful in making this for medications. Can you help me make nutraceuticals with it? Like vitamin C and CoQ10 and PQQ and S Xanthine and Glutathione and so on and so forth. And so we made the products for that doctor. And then a couple of years later. Some work, some did not work. Gluten was one of the products that did not work. So I go back and says, why is that working on everybody? The question I always ask is, hey, it helped my girlfriend. How come it's not helping me? Or it helped my sister. Why, how come it's not helping me? What, what, what am I, how am I different than the other human beings? and in reality, only your face is different. Internally, we are identical. A body has the same heart, the same organs, everything is the same, right? So we have not changed for the last 40, 000 plus years, [00:11:00] how to expect that I'm different than my sister, or I'm different than my girlfriend, or whatever, right? Maybe your genomic mixture is different, but your overall organs and organ systems are identical. And so to me, I said, okay, if it works in one person, it should work on everybody. If I get absorption in one person, I guess you should get absorption in everybody. What's the rate limiting factor? Why is it not happening? And so I didn't have answers at that time. I did not know what to do. So next story is that, okay, you know what? I'll make the intravenous form of glutathione. Hey, if I inject him into the bloodstream, my job's done. Again, took me a few months to figure that portion out how to make that part. And yes, This is long story short, we were Well, again, we were one of the first company pharmacy early on in 2001 to make the injectable form of glutathione. Now, very quickly, we realized that the effects of this glutathione was very short, right? And then I looked back in the research and said, there was a study done in 1991 [00:12:00] saying that if once you inject glutathione, it only stays in the body for between four It takes five to 15 minutes and everything gets destroyed or gets, get, get, it gets into the urine and you pee it out, but an hour and a half later, there was an increase of cysteine, which is one of the amino acids that went up in the blood. And so the researchers concluded that the body was breaking down this glutathione and cysteine was getting reabsorbed by the body and cysteine is being used for your body to produce its own glutathione. I said, okay, I don't care how the body makes it. As long as the body has a gluten, I don't care. But the results were very short lived. And I don't know if you know this thing, but back in early 2000s, one of the doctors came to me. I said, Hey, if it's short lived, that's okay. Let me take you to Vegas because when people drink, they deplete their glutathione levels. If it only stays for 15 minutes, I can revive somebody who's passed out drunk of their minds and I can get them. So. He literally took this product to Vegas and [00:13:00] start helping patients. I read scripts for those kinds of things. And again, I have nothing to do with it. I, unfortunately, I was just the supplier and I was just the maker of the product, but we saved so many lives. We helped so many people, but we were, we learned one thing that the action was not long term. And if I want the long term benefits, because if it's one of your patient, if it's one of your listener, who's, who's trying to get pregnant she, or he has to plan for A 30 day cycle, not a 15 minute. Give me some push right now and I'll be done. No, it's a 30 day cycle. You have to plan everything methodically, right? What am I supposed to do from day one to day seven and from day seven to day 14. And after ovulation, what do I do? And after post ovulation, if there's an embryo implantation, what do I do? And so on and so forth. It's a, it's a whole process and your body needs to be clean this whole time. And none of the products were actually getting the results I was looking for. Later on, I found out, this was 2011 [00:14:00] University of Texas in Austin did a study on the liposome technology product of glirathione. And what they found out was same thing that they saw in intravenous form. The body actually breaks down the glirathione, never absorbs a single molecule of it. Absorbs the cysteine and cysteine is later used to produce his own glutathione. And the end story is, it still works. It still works. But people need to understand, just because it works, it does not mean your body absorbed it. And there's a there's a difference between that one and maybe some people may not appreciate that part But I do appreciate that part because in my case i'm dealing with thousands of patients across the country across the globe now And I want to make sure that I want to give assurance to everybody that hey if I give you a glutathione product No matter what it is going to get inside your body [00:15:00] and absorb it And so the liposome technology product was great until now People got a lot of people got results for almost 80 got results from it but not because it absorbs it because the body was able to Conjugate or take the cysteine and make its own glirathione today Today the things have changed now. Why? because 15 20 years ago We started doing gene testing gene snips You Right at that time it was nobody can afford it. I was fifteen twenty thousand dollars for a blood test Oh gosh, no, nobody can afford that today Same test is 200 bucks 300 bucks, **Michelle Oravitz:** Right.  **Dr. Nayan Patel:** right? So now what's happened is that now everybody's doing these gene testings And finally got hey, do I have gene mutation where my body cannot produce gluothione if the answer is yes Then I don't care how much product you take from outside sources, the body is not [00:16:00] able to effectively produce glutathione correctly all the time. And so that to me is one more proof, one more proof that we need a product that your body can actually accept it, incorporate into their own DNA and use it when it needs to. Anyways, I just went off too many tangents no, Thanks very much, interesting. I want you to continue. So how did you find out and, and like how did you discover the product that you have now and what kind of technology does it use and how does it really impact the body? Absolutely. Those **Michelle Oravitz:** nerd in me wants to know **Dr. Nayan Patel:** Yeah. All great, great questions. And I want to, I really want to be an open book. I don't want to hide any information from anybody so that I'll be more than happy to open it up and let everybody know. So earlier when I first started the book. So we had a, we had a couple of barriers. One, what we knew was the body's not going to take any peptides, any amino acid chains to get it to and incorporate it into their own DNA. [00:17:00] What we, what I found out was the body has to make 100 percent of all peptides in the body, the body has to make it. Right. So we knew that I knew that part very early on. So I said, okay, there is no way on earth I'll be able to make a product that your body can use it up. Okay, so now I had to figure out Okay, how do I get this simple tripeptide three amino acid chain peptides into the body? So I first of all, I want to do, I want to create a stable molecule because if I have a stable molecule in my lab, I can work with it. If it's unstable, I don't have time to really experiment on it, right? So my first goal was to make a stable molecule. So that we achieved pretty fast. It took us a couple of years when we got the stable molecule. We took it by mouth. Again what we saw was Sistine went up, so it was not working really, it was getting broken down. We scored into the nose, I said, and if the nose was burning, I said, oh, nobody's going to use this on a daily basis. Of course not, right? It's not a, it's not a fun thing to do. I knew the [00:18:00] injectables was a little bit of an uphill battle because it requires FD approval and all those things. I said, you know what? The only route that was remaining was skin route. And of course, skin is a physical barrier, right? So it's a physical barrier that I have to overcome. And the physical barrier is, is a particle size barrier. So I had to reduce the particle size so small, It can get through the cracks or the pores of your skin and get inside your body. So that was the first challenge I had, which we were able to crack the code in about a couple of years. We had to take this peptides, twist it in such a form that doesn't get broken apart and gets a small, you know, like when you twist the towel, you know how it gets smaller and smaller and smaller, but you twist enough, it can get really small. And so that's what we did with this molecule. It forces microscopically, and we were able to reduce the particle size to much smaller. We got to the skin. The bigger challenge is this glutathione is inside your cells. So now the issue is that, [00:19:00] okay, we release a particle size, we get through your skin. Now, so the physical barrier, we, we all work in the physical barrier. The second was a chemical barrier. Because the cell wall is a lock and key. Hey, you say the magic word and the castle opens up and you can go inside. But if you don't say the magic word, the castle will never open for you. So the question then becomes is that what does the body needs? What does the cell needs to survive? All your mitochondria, the energy powerhouse in your body is in the cells, right? And that to produce the energy, what you need is carbohydrates and sugars. I cannot give you sugars because I give you diabetes and we already have an epidemic of diabetes in the United States across the world nowadays so I said, okay, how do I get a polysaccharide sugar type molecule? That doesn't doesn't do anything about the sugar is completely inert FDA has tested it out and it's completely safe to give to anybody pregnancy no pregnancy children's everybody And can I use that molecule? So we found [00:20:00] dextrin technology. This was a technology that has been out for about 20, 30 years now, but there are no good medications in the world. As even in today's state, there's not too many medications out there. People are still dabbling around. those technology products. And so we use the technology to literally, instead of working with medications, we start working with glutathione. We do the sugar molecule and stuff inside with glutathione. It's like, do you need M& Ms? Do you need **Michelle Oravitz:** No, not anymore,  **Dr. Nayan Patel:** Not anymore,  Okay, Good. Good. Do you, do you eat M& Ms for the peanuts or for the chocolate? **Michelle Oravitz:** I guess well, I used to like the chocolate ones when I was really, really little. And then later on peanuts, **Dr. Nayan Patel:** Exactly. But the thing is, you don't eat M& Ms for peanuts, you eat M& Ms for the chocolate. But the peanut inside, if you get a peanut, do you spit it out? Or you know what? It's not so bad. I can use it up. **Michelle Oravitz:** It's like I compare it to like, you know, the being able to take those pill things for your dogs where you put it inside a treat and get the dog to eat it. And[00:21:00]  **Dr. Nayan Patel:** That's exactly right, right? So I took the carbohydrate, the sugar molecule, stuffed the glutathione inside, you know, so the body, when the carbohydrate hits the cell wall, the cell goes, oh, I can use this up. Right? And sucks it in. Inside is glutathione. But he goes, well, I can use this up too. It's not something new to me, so I can use this up too. Right? And so now, it's like you somebody tells you that, hey, I have a billion dollar coming to you, but it's coming in the mail. Well, that's not helping me right now, but if it hits my wallet, gosh, I can spend it today. Right? So, you can check the mail, it's in a transit, but until it hits the wallet, you cannot do anything about it. Saving glutathione, if the glutathione is in your body, but it's not inside your cell, the, the cell says that, okay, I need the glutathione, but it's way out there. It's not in my cell. I cannot use it up. Here we got inside the cell directly. [00:22:00] When we did that part, like magic just happened. All of a sudden, the body has a product. The body needs it. The money's in the wallet right now. I can go spend it today. And the body can actually use the glutathione immediately To start doing what? Two things that we know of as of right now. One is start neutralizing all the free radicals. That's number one. Number two, start getting my liver cleaned up and start detoxifying all this, all this metabolism in my system. When you do those things up, all of a sudden your whole body or your temple, your, your the sanctuary in your body starts getting healed from inside, starts getting cleaner. And all of a sudden the, main thing, which is our sperm and the eggs. Are not been invaded or not been attacked by this toxic chemicals. **Michelle Oravitz:** Right? **Dr. Nayan Patel:** And so that's, there's, there's my technology. We discovered this in 2007, as you can imagine 2007 it was too far [00:23:00] ahead of the game. There was nothing in the world that exists something even close to this thing. And so there was no studies being done. There's no research articles published. There's nothing out there in the world that I can fall back and say, Hey, go ahead and use it safe. **Michelle Oravitz:** Yeah.  **Dr. Nayan Patel:** do that part. So it took me another 13, 14 more years to literally do everything that I can do on my own. I have no funding. I did everything on my own. I put every single thing I have back into this to basically research it out. Apply for the patents, all my work that I did. I, in fact, I published a book about three, four years ago. All the work I did for the first 13 years, I put in a book. I said, Hey. Guys, here's read it, right? This is this is all my work and it's just success stories that I've given to patients and clients and And found friends and family that uses product and and see how how much benefit they got in different areas of life right if you're an athlete versus if you have metabolic disorders versus you have [00:24:00] metabolism, defects if you're on the spectrum because spectrum patients have some sort of Metabolism issues of detoxification issues that they cannot clear the toxins out of the body And they are the autism or aspergers or whatever they got right? So i've all the stories and I have some stories about horses and and dogs and how how they it helped them as well in their in their wellness, thing as well as anyways So that's all the stories in the book the glutton revolution. That's my book. But after everything got done We had a pandemic **Michelle Oravitz:** Right. **Dr. Nayan Patel:** the product was not even released yet You And the pandemic comes around and I've been begged by all the doctors around the country. I said, oh my god Please give us the access to the glutathione because I was working with doctors So they knew about this product, but none of the consumers knew knew about it And so that's when we actually did a soft launch. We didn't have a bottling. We didn't have a boxing. We have nothing at that time No website, we had a website, but it was like a nothing nothing crazy So 2021 [00:25:00] was the first launch of the product now we are here today, but, so anyways, so thanks for asking me this question, but I just wanna make sure the story **Michelle Oravitz:** Yeah, no, I love the story because I think also I have very, very smart listeners, I'll be honest, like with a fertility journey, they are so educated. You know, it's such a motivator to really educate yourself. And a lot of times if I work with people in person online, I see the most educated people, they really know a lot. So I wanted to kind of have a background to really explain how the process works. Cause I feel like it's very empowering for them. And the two things that I know, like an N acetylcysteine. So that works as a precursor to get the cysteine. And then from that gets the body to produce glutathione. And then your product works through the skin and then is enveloped by the carbohydrates, right. Or the yeah,  **Dr. Nayan Patel:** is, it, it's, it's a polysaccharides is what we call 'em. And it's embedded inside that one. It's the, analogy I can [00:26:00] give you is that, hey if you need money, there's two ways to get money. One is I'll give you a job. You work at it. And you, you share your trades and then for the reward, I'll give you money. The second part is here's the money in your wallet. I'm not going to give you too much of it. I'm just going to give you enough to survive the rest. You still have to go make it yourself. Right. And so the second part, I give you enough to survive. Your body says to make the rest of the glutathione from the foods you eat and things like that. but a lot of people need, just need a little edge over everybody else. So I just give them extra glutathione to make sure that they are able to use up right now, because when you have a problem today, if you need the money today, and if you give you a job, I said, that's good, but I need the money now. I don't need money two weeks from now.  **Michelle Oravitz:** Yeah.  **Dr. Nayan Patel:** And so that makes it very, very useful. And in, in certain cases, I'm not saying that is good for everybody. What I am saying that is good for everybody, but the product may not be good for everybody,[00:27:00]  but having a healthier lifestyle, having the cysteine rich diet. Is absolutely a must I don't care what what age you are, right? That is absolutely a must So if you do that, if you have a healthy lifestyle, that means avoid the toxins that depletes the glutathione levels Having the diet that consumes that gives all the amino acids those two things combined Will will give you a fighting chance for long periods of time where you don't need any supplementations The supplementation is very good for people that need extra help or temporarily And then once your body gets under control then you can stop it, too **Michelle Oravitz:** Yeah. And then, so the couple of questions that come to my mind is you know, I'm, I'm a, also a big believer, obviously it sounds like it's doing something, but I'm also a big believer that like nature has a very a method for its madness. And I'm wondering, is there a reason why it's under such lock to allow um, glutathione in by itself, rather than having the body produce it? It was just [00:28:00] kind of like something that came to my mind.  **Dr. Nayan Patel:** know.  **Michelle Oravitz:** you were mentioning that. **Dr. Nayan Patel:** and you're right. I mean, the body is, is equipped to deal with, because any peptides that you, that the body can accept from outside sources can actually get embedded into your DNA. And so having the purity, what if you give somebody else's DNA inside your body? **Michelle Oravitz:** Right. **Dr. Nayan Patel:** Wow. Right. Think about it. Think about it. You're injecting somebody else's DNA. Some, some of the protein from something else that is not made by humans. The body is going to start going to cycle, react to it and say, Oh my God, what if well, we have vaccines right nowadays. What are the vaccines are proteins by outside of viruses, right? How about we use those embedded into our own DNA? So that's the, that's a scary part to me. And so that's the reason why a body does not allow anything from outside sources to get inside your body. It's very [00:29:00] very protective. Glutathione we do know is produced endogenously. It's inside your body, making sure that the glutathione the raw materials that we use Is of the highest highest quality. I would say 99. 99 percent pure is what we need. Otherwise, we just going to have a chance of making sure we have a chance that we can harm our body. And so just so for when I, when I first heard that in 2007, I quickly, I realized that I have to bring manufacturing in house. I can't trust anybody to do this for me. It literally took me eight years to build my own plant out small plant But just enough so that I can control every single thing making sure the water that I use is the highest quality Everything that goes inside is for the highest quality products. That's why I had to Ensure that so I brought everything in house. It was too costly to make it It's still too costly to make it and to [00:30:00] reduce the cost. I had to make sure that I I am, I'm going straight from the manufacturers to the consumers and there's no too many middlemen in between to reduce the cost down. And so we've been doing whatever it takes and you're right. The by doesn't take it. So having that technology to bypass this is somehow empowering that we can do that part. But it's scary is that we can use the same technology to, to hurt somebody too. **Michelle Oravitz:** Mm hmm. Yeah. Yeah. For sure. And thank you for answering that. And also, my question is, what have you seen in the research? Like, what have you seen short term, long term, because you, it sounds like you guys have been working with us for a long time, in the response of people's bodies and conditions. **Dr. Nayan Patel:** Absolutely. So just FYI of a human body gets everything gets, gets redone every 30, 60, 90 to 120 days. That means you get new cells in your bodies all the time.[00:31:00]  The body is constantly constantly making new cells, better cells so that you can rejuvenate yourself from inside out, right? So the body is, it's like you're having a house, constantly remodeling your house from inside all the time, right? So no matter what happens, if I make a hole in the wall, you know what, a few months from now it'll be a brand new wall again. I don't have to do anything, just have to wait and don't make it further damage the wall, right? And it'll be repaired by itself. So the body repairs itself. The issue is that. The glutathione can actually improve the repair process to the point where it repairs better. And you can feel the effects much, much faster. Now certain organs take them 12 to 18 months to repair. For example, liver, it takes a long time to repair. So, any, if you're looking for benefits for liver health that may take anywhere from 12 to 18 months. Even though if I have doctors I work with all the time and the doctor says, Oh, my, the liver function tests are coming normal. I said, just because the tests have [00:32:00] no, that doesn't mean the liver is normal, right? I guess you're right. Absolutely right. So they do ultrasounds. They do scans and things like that to figure that portion out. But again, it takes them 12 to 18 months to fix it. At a short term people when they have have issues with oxidative stress. The biggest issue I've seen is these are, these are people that have some gene mutations that cannot produce, they cannot conjugate and make enough glutathione. They have this brain fog that has been lingering on for decades, decades, right? For 10, 20 years sometimes. Of course, these are older people. These are not 20 year olds. And so they've been struggling and All of a sudden, they use a gluotide and about 15 minutes later, they can just see the, just brain just opens up. Now, it is not a, it's not a something to improve your memory. It's not this magic pill that you see in the movies. It's here, one pill, my brain just fires up and I'm, I can think and I can do anything I want to do. It's not that pill, it's a **Michelle Oravitz:** but I'm sure it can prevent things like Alzheimer's or things like that. Mm hmm, [00:33:00] mm **Dr. Nayan Patel:** well, Alzheimer's and Parkinson's and things like that as well. But in the short term, when people see the brain fog clears up, all it's doing is reducing oxidative stress. **Michelle Oravitz:** hmm. **Dr. Nayan Patel:** If you need to reduce oxidative stress, so I've seen results as much as 5 to 15 minutes. Up to two to four weeks in most individual And two three to six months in I would say 99 of the people they see some improvement in their health and wellness and they're most of them are working with the physicians So they're doing some blood tests before and after the doctors are saying what the heck you're doing I don't know what you're doing, but keep on doing it. It's very good for you. So  **Michelle Oravitz:** That's really interesting. And then also, if you were to get, you know, outside source of glutathione, the body feels the glutathione, will it make an impact on the body's own production of glutathione now that it feels that it has more. **Dr. Nayan Patel:** Absolutely. And the thing is [00:34:00] the the biggest concern that people have that hey What if if I take glutathione from outside sources with my body shut down his own production? And yes and no, I think the body probably may reduce the production, it probably will not shut it down because keep in mind when we're comparing, because most people have been burned by, hey, if you take steroids, your body will, it'll blow up like a balloon and because the body is not able to make its own regular, its own steroid production, which is true, which is 100 percent true. endocrine system is tightly regulated from your gonadal hormones, your pituitary and your ovaries and your testes and to the brain, which is the pituitary the hypothalamus, right? So they both work together, your brain tells your ovaries to produce the hormones, the ovaries produce the hormones, the ovaries cannot produce the hormones, The brain is going to keep on sending signals. Can you do more? Do more? Do more? Because I can't do anymore. I'm already tired. I'm burnt out. I'm just, I'm shriveled up. I can't do anymore. Right? Versus if you [00:35:00] take a hormone from outside sources, it affects straight to the pituitary. And the pituitaries will shut down and say, Hey, no more producing hormones. You got too much. I don't know where it's coming from,  but  **Michelle Oravitz:** like a thermostat,  **Dr. Nayan Patel:** Right? It's a negative feedback. But when it comes to glutathione, glutathione is not triggered by any brain or hypothalamus. Glutathione is taking three amino acids together, two enzymes, two molecules of ATP, which is energy, and one molecule of NAD for electron transfer. All this to come together to make glutathione. Right? Now this same energy, ATP energy, NAD energy is being used in thousands of chemical reactions that happens every single day. So keep in mind, if your body does not have to produce glutathione, your energy is never wasted. It's used to do other reactions all day long. But the good thing is that glutathione is by far the most abundant molecule produced in the human body. [00:36:00] And after a couple of weeks or so, the body is saying, hey, everything is not working great. Now for two weeks later you see some increasing energy because now the energy is is Getting excess and your body goes. Oh my god. I have excess energy now all of a sudden. It's not a car It's not a caffeine type energy It's not like jumping up and down type of energy, but you do feel good from inside out Right. You do feel good. And all of a sudden you pick up other habits, walking, jogging, cycling, you know, or just going out and just, you just have this, this energy inside your body that you want to do other things. You just feel alive from inside. And so, and then when you stop the glutathione, the body says, okay, oh, should we have, we need more glutathione. So the first energy goes towards producing glutathione, but if you have enough glutathione, that energy has been used to produce other peptides. Keep in mind, a muscle needs what? 6, 100 amino acids coming together. Takes a lot of energy to produce muscle fiber. So if you're not [00:37:00] using the energy to produce glutathione, hey, hopefully it goes to producing more muscle mass. I'm hoping for that. **Michelle Oravitz:** Yeah. . And is there like a limit on how long you should take it? you know, is there a limit that you have? **Dr. Nayan Patel:** So, I do know that your body needs glutathione until the last day you die. So, until that day, you have to take it. After you're dead, I'm not sure if your body needs glutathione or not. So, that's a joke. I'm sorry. But your body needs glutathione to survive. Every single day. So the needs are going to be the endless. the better question to me is that do I need to supplement every single day of my life? That's a way better question for me to answer is to that that question came to me in my mind long time ago as well. And so what I have found out is that the body needs glutathione. to survive. Your body has the ability to produce glutathione, plenty of it on a daily basis. And what I found in [00:38:00] my research that up until about the age of 30, there is no need for any supplementation. None. Improve your diet, reduce your exposure to toxicities. You should be fine. **Michelle Oravitz:** Right?  **Dr. Nayan Patel:** Between 32, 35, if you have a healthier lifestyle, don't drink alcohol. Don't expose yourself to heavy levels of toxicities. Don't do sunbathing a whole lot. And having a very clean diet, you might still be okay. 35 to 40, I would say 80, 90 percent of the people may need to supplement gluathione, over 40, I have yet to find somebody who has normal levels of gluathione and so the question that I ask is, Hey, what's Well, my mom in the fifties and sixties never had to use a gluathide, and she lived for long periods of time, so why is it today, right? But keep in mind, at that time, sixty years ago, maybe the world population was three billion, now we are eight billion population. And who are the biggest polluters in the world? Is it the [00:39:00] animals or the humans? **Michelle Oravitz:** Humans. **Dr. Nayan Patel:** Humans. Animals don't even wear clothing. They don't even do anything. They don't have to build any houses and, and destroy the world. They just live, enjoy the world and leave the world the way it was when they came in. Us humans wants to fly, wants to build a hundred story buildings and wants to drive cars and wants to do all kinds of things. So we are the biggest polluters and the pollution has literally what more than doubled in the last 60 years. So if we say that the, the modernist society is polluted, the answer is absolutely yes. And it's not, it's not like we are turning the tables and we're going on the other way around. So like it or not, nobody's willing to give the modern day conveniences at this point. They don't, they're not going to do that part. So the question is that yes, Maybe my mom did not need gluten until the age of 50 or 60 [00:40:00] maybe. That's dropped down to 30, 35 or 40 at this point. And I'm scared for my kids because they may need glutathione at the age of 25 That's that's not a good thing to do, but it's just just telling us that our memory is getting more and more polluted and we need to figure out every single thing that we can do to enhance our body to stay clean from inside. **Michelle Oravitz:** And is there a benefit to taking N acetylcysteine as well as the, the skin,  um, supplementation?  **Dr. Nayan Patel:** okay, so NAC or cysteine so there are about eight essential amino acids that you have to take every single day Cysteine is not one of them Cysteine, Glycerine, and Glycine. Those are the three amino acids that's used to produce glutathione. Those three are not even in the part of the eight essential amino acids. So if you take cysteine and the glutathione topical version that we have, the cysteine is not going to be used up to produce glutathione at all. It may be used up for some other components, but not for [00:41:00] glutathione. I would suggest that if you're doing that part, then save your money and just improve your diet, right? If you have the money, I would rather you invest in those eight essential amino acids. Those are much better to do that, like Lucid and Proline. And so those are much more better to for you to use it on a daily basis. I'd rather you spend the money on that than to spend the money on the SysTeam. **Michelle Oravitz:** Got it. And then what are some of the foods and, that you would recommend for the glutathione diet? **Dr. Nayan Patel:** Michelle, I've been told not to advise people on diet **Michelle Oravitz:** Okay. Thank you **Dr. Nayan Patel:** is worse than the religion and politics. So I'm going to tell you one thing. All right. So everybody has a, has an AI robot. Everybody has access to AI robot. Go type it up.  Sistine rich foods. **Michelle Oravitz:** Sistine Richards **Dr. Nayan Patel:** You're going to get your vegan choices, vegetarian choices, carnivore, [00:42:00] paleo, Atkins. I don't know what a longevity diet. I don't know. Don't die diet. I, I don't know. There's so many diets out there right there right now. All these diets are going to be satisfied if you just type in the word system food and see what food are you willing to eat and make and have a variety of foods from that list that you consume on a daily basis. Like what's in that list? I, you know, on an everyday basis, every single day.  **Michelle Oravitz:** Yeah **Dr. Nayan Patel:** in there, asparagus in there, there's oysters and chicken and turkey. And I mean, you can name it, right? There's so much stuff is in there that you can consume. It's not a small list, right? But you have to make it a part of the routine. But that's just one thing. That's just one thing. The second part, which is utmost important, is limit. Limit your exposure to toxicities, **Michelle Oravitz:** yes true [00:43:00] Oh, **Dr. Nayan Patel:** pure. Right is important and because of that guess what my technology I even dove into the skincare as well because because most of my customers were females. Well now they are like 50 50 today But at that time all my customers female and they look at the technology and say hey Can you give me all the antioxidants for my face as well? I said sure. It's that's easy, right? So I just went got all the antioxidants and I said, okay Put it squeeze the size right so I can shove a whole bunch of stuff into this couple of products And so I have like seven or eight different antioxidants in full concentration and some are even more in like two creams right And then two of the serums I give like 10x of what you what you get from any of the products in the marketplace today so I give you a vitamin c and glutathione in a very high concentration to your skin Gets your skin completely disperses really really fast and gets gets to the all the skin in your whole body And so anyways, so I did that [00:44:00]  **Michelle Oravitz:** if you do that, To your face, is that the same thing, the same technology that will get glutathione in your cells? So it's kind of like two in one? **Dr. Nayan Patel:** So it is, it is it's the same technology, but what we have to done is we have to identify the speed and how deep I want to go inside. So the skincare is more  for,  **Michelle Oravitz:** different. It's more  **Dr. Nayan Patel:** yeah, but I would always say that if you're using both that do not double up, do not double up, right? If you're using both that your skincare routine, as is the way it's been introduced to you, and then just add on the, the top of glue that just once a day. **Michelle Oravitz:** I  **Dr. Nayan Patel:** And you, and you still get the, I mean, you get full benefit. That's the ultimate Longevity hack is what I call them, right? Cause the beauty is inside out. The ultimate longevity hack is you do the full skincare routine and just do once a day of the glutathione. If you don't do the skincare routine, just the glutathione twice a day is, is, is, is what you need. That's an ultimate bio is, [00:45:00]  **Michelle Oravitz:** Oh, that's great.  **Dr. Nayan Patel:** I have. **Michelle Oravitz:** Well, listen, I mean, I'm curious. I'm sure people listening are very curious, how can we find out more? How can we buy this stuff and get ahold of it? **Dr. Nayan Patel:** Absolutely. So, my website is oral wellness. com. A U R O wellness. com. Go to the website. There is a two part on the top is skincare and wellness. Otherwise you can go to oral skincare. com as well. The same thing. My urge is that if you are any of this patients that is Not able to give up monitor conveniences or you may suspect that you may have low glutathione levels I would probably strongly suggest you try it for 30 days It is,  we do offer a hundred percent, a hundred percent money back guarantee. We don't charge shipping and handling. We'll refund you everything, right? We will, we will do full refund of everything. Cause I just want people to try it out. And once you try it for 30 days and if you see slight benefit of [00:46:00] it then it's the best thing that can happen to you for the rest of your life. It's one thing that I have, I have customers for now for 17 years, since the first we discovered this product. That will, that's like a, it's a go to product in the arsenal. It's like, it's always there. And I'll tell you, I'll give you another analogy right now, because I wanted people to really understand what this is, because as you age, your body is deteriorating, is diseased, and it is, is, is breaking down, right? It's like. You go to your, when you go to your home you leave your door open. And as soon as I leave the door open, the dust, the wind blows the leaves inside. And so what you do is you bring your vacuum out or your, or your broom out and start sweeping and guess what? There's more dust and more leaves coming out. Right? So what do you do? I'll say, Oh my God, I forgot to close the door. Once you close the door, you can literally clean the whole house from inside and make [00:47:00] it brand new again. Right? Oxidative stress, oxidative stress, production of free radicals is the opening of the door analogy in your body. Oxidative stress is not doing anything, but it's allowing every single thing to come inside your body. And destroy the body from inside and unless you block that and close it up You cannot buy your body does not heal from inside, right? So the glutathione is actually closing the door is actually closing the door and then allowing your body to what to start getting? Cleaned up from inside and start repairing itself inside So at the bare minimum at the bare minimum if you do for four months You're going to have every single day Products in your body, every single cells, organs, every single thing you're going to have allowed them the chance to [00:48:00] regenerate self. **Michelle Oravitz:** Yeah.  **Dr. Nayan Patel:** after four months, yeah, it's after four months, it's like game over. So I have people that even today's they, they said, I know what I have to do. It's just that I just keep on forgetting. I said, that's okay. You know, close the door first. You know, it's, it's no fun sweeping and wrecking your house every single day. **Michelle Oravitz:** No, no, it's not. I agree. Wow. This is amazing. Really, really fascinating information. I just love the fact that you have a background from, from ecology. I mean, that you understand it really from the inside out and that you were able to apply technology and really understand it from your perspective and that you had these ideas to create a product like that, that's really cool. **Dr. Nayan Patel:** and I, I wish I had this product when we were going through our early on in my life because my wife had a hard time conceiving and it took us nine years to have a first son. Yeah, and it's not that we were trying for nine years. It's just that [00:49:00] after marriage, it took us nine years to have the first son and we only tried for maybe about a couple of years before. And then. We did, I think we did one, one, I think two IVF cycles. And I said, this will be the last one. We'll never do it again because I know the damage it causes to the human body. And I wasn't the one suffering, but I know it was going to destroy her body for the rest of her life. So I was not willing to put up with make her go through the process, even though it was like something that is so blissful to you, right? When you have a kid. So, yeah, we did all the traditional because I was pharmacist. I knew I'll do all the hormone therapies. I did all the hormones correctly. Everything was just fine, but she just was not producing any follicles. The follicles were there, but they're not producing any eggs. I knew that it was oxygen stress, but at that time I had nolu thi product in me. And So uh, it is just so unfortunate, right? But today you have that if you are a young person that is trying to conceive you have this thing, [00:50:00] at the very least, just use it for a few months. It gives it by the chance. And and, and hopefully you have a healthy baby. That's, that's always my **Michelle Oravitz:** Yeah, that's the hope. Yes. And sending all of that good, good energy and good thoughts to everybody listening. So thank you so much, Dr. Patel for coming on. This is a great conversation. I will have all the links to the website and everything in the episode notes for people to view if they want to stop, stop the car and then go look, but thank you so much for coming on today. This is a great conversation. **Dr. Nayan Patel:** Appreciate your time today. It's my pleasure to be here today. Thank you. [00:51:00] [00:52:00]     

Pyrroloquinoline quinone (PQQ) is a powerful, vitamin-like compound discovered in the late 1960s and recognized as a key nutrient for cellular health and longevity. It plays an essential role in regulating fundamental biological processes, offering a wide range of anti-aging benefits. From boosting brain function and heart health to supporting mitochondria, bones, kidneys, skin, and gut health, PQQ is a true powerhouse for overall wellness. Keep reading to discover why this nutritional dynamo is gaining attention for its incredible health-boosting properties!In this episode, George discusses the amazing benefits of PQQ and how it can be 5X more efficient than even Vitamin C. www.georgebatista.com

On today's episode of The Wholesome Fertility Podcast, Vida Delrahim and Ronit Menashe share their personal journeys from corporate careers to founding WeNatal, a company focused on improving fertility through better prenatal supplements. They discuss the importance of addressing both male and female health in the preconception phase, the science behind their product formulations, and the need for education and resources for couples trying to conceive. Their mission is to empower individuals with knowledge and high-quality supplements to enhance fertility outcomes.   Takeaways Ronit and Vida met at Nike and became best friends. Ronit's experience in functional medicine changed their trajectory. Miscarriages led them to explore fertility solutions more deeply. Men contribute to 50% of miscarriages due to sperm quality. WeNatal was created to support both partners in fertility. Their prenatal supplements are designed for bioavailability and effectiveness. They focus on simplifying the supplement process for women. Education is key in supporting couples on their fertility journey. Their blog offers valuable resources for those trying to conceive. They emphasize the importance of quality ingredients in supplements.   Guest Bio:   Ronit Menashe and Vida Delrahim are the founders of WeNatal, a prenatal supplement company that is transforming the fertility space with the first prenatal supplement optimized for her AND him. WeNatal's mission to change the narrative surrounding fertility and reproductive health is personal; after suffering miscarriages a week apart, Ronit and Vida were given little direction on what to do differently. More importantly, the health of Ronit and Vida's partners(including the health of their sperm) was completely missing from their fertility dialogue with their doctors… something had to change. That is why WeNatal was born, to shift the fertility journey from "me" to "we.” WeNatal is revolutionizing the prenatal space and backed by industry leading Functional Medicine doctors, nutritionists, and fertility experts, including Dr. Mark Hyman and Kelly LeVeque. With 24 key clean, bioavailable nutrients, WeNatal steps up where other supplements fall short for all things preconception to postpartum for both parents and baby.     Websites/Links:    Free Preconception Guide:  WeNatal.com/guide     https://www.instagram.com/we_natal/?hl=en   For more information about Michelle, visit: www.michelleoravitz.com   Check out Michelle's Latest Book: The Way of Fertility! https://www.michelleoravitz.com/thewayoffertility   The Wholesome FertilityFacebook group is where you can find free resources and support: https://www.facebook.com/groups/2149554308396504/   Instagram: @thewholesomelotusfertility   Facebook: https://www.facebook.com/thewholesomelotus/     Transcript:   Michelle (00:00) Welcome to the podcast for Neat and Vita.   Vida Delrahim (00:02) Thanks for having us. We're so excited to be here.   Ronit Menashe (00:04) So happy to be here.   Michelle (00:06) Yes, so happy to have you guys. And I know that you guys have such an interesting story, first of all, on how you met and also the experience you guys went through together. So without giving anything away, I would love for you guys to share your stories, your personal stories and how that eventually led you to doing your passion project.   Vida Delrahim (00:26) Yeah, I'd love to. So it's fun story because we never envisioned to be in the supplement space. And in fact, Ronit and I met in our corporate careers at Nike close to 18 years ago and became best friends and really just kind of embarked in life together. Ronit went on to work in the functional medicine space and we should all thank our lucky stars that she did because it kind of completely changed our trajectory. So.   I had a miscarriage right when she was having her first daughter. And of course the answers we were given were very dismissive. They were typically like very common, keep trying, you're lucky you even got pregnant, could be the stress, could be a slew of things. They just kind of shove you along as part of the process. And I didn't know any better, of course, having my first and Ronit was actually in the functional med space, immersed and kind of taught me things like, have you checked your thyroid? Have you done this? Have you done that?   Lo and behold, I had Hashimoto's, I didn't even know about it. Just that simple act of fixing my thyroid with medication and visiting an endocrinologist allowed me to have a healthy baby girl. And then fast forward to 2020, I had another miscarriage. And a week after, Ronit had one. And I think this was, it happened a week apart. This was a little bit shocking because...   Like I kind of just accepted that this stuff happens, but Ronit working alongside Dr. Mark Hyman, who's very amazing functional practitioner, she was all about the root cause. She was all about the answers and the questions and the answers she was given was very similar, but she wasn't willing to accept that. Like, you know, there's nothing you can do as an answer.   Michelle (02:02) Mm-hmm.   Ronit Menashe (02:03) And I think for me, Michelle, the reason why it was so shocking was because I was a huge fan of functional medicine for so many years and I already was doing all of the things, or at least I thought I was. I had already cleaned out my house from plastics. I had already, you know, was eating organic food. I was focusing on movement. I was taking pretty good supplements.   or at least what I thought was good supplements. And I was shocked. And when I started to dive into the root of what was happening, because it didn't make sense to me that my doctor said, there is nothing you could do to improve your fertility, literally. It is just common, just keep trying. I thought that makes zero sense. And I'm gonna learn about how to improve my egg quality. I thought.   Michelle (02:48) Mm hmm.   Ronit Menashe (03:01) It was a net quality issue. was 41 at the time. That's what made sense to me. And my biggest aha was when I learned that 50 % of miscarriages happen because of sperm quality. And that was when I called Vida and I said, Vida, did you know that men contribute to 50 % of miscarriages and that 50 that   that sperm quality is easily improved using antioxidants like CoQ10 and AC. In fact, studies after studies show that when men take an antioxidant blend in high dose bioavailable forms, they can quadruple their chances of their partner getting pregnant and having a live birth. So,   That was our big light bulb moment when we thought like, my God, we need to create a prenatal for men. And we need to scream this from the rooftops that men have a huge role, huge role in improving fertility outcomes and pregnancy outcomes for their families. And that was where we started our journey.   Michelle (04:13) It is so important. can't even like tell you. It's so crazy because I have people that go to their doctors and so many times they don't even check the men. And also the DNA fragmentation, which is a whole other thing. Cause like, yeah, you can have perfect sperm numbers and motility and morphology. But if the DNA is off and that can get really impacted by the antioxidants,   then that can make a big difference on so many things on IVF, is so expensive too. So I love that you guys bring this up. It's so important.   Vida Delrahim (04:50) It's so important and how is it that we're so far in like medicine and women's rights, but like yet the burden of fertility still solely is falling so Ronit and I knew that was like the beginning of our mission that one, women and men deserve better products because we can talk about how   once we uncover the fertility and the supplement space, we learn so much, but also that they both need to be leveling up their health. They both need to be part of the conversation. And WeNatal was really born to really level up both partners and bring them together during this journey and give them the best tools and the best nutrition to level up their health in this crucial timeframe, which is preconception.   Michelle (05:32) For sure, and we're neat. So you had a different background and you changed your career like me.   Ronit Menashe (05:38) Well, my background was in marketing. That's where Vida and I met at Nike. And I fell in love with functional medicine when I got into CrossFit and I learned about the Paleo diet. And then I learned about functional medicine. And then I started to do, you know, become, I became a functional medicine patient myself. And this was a year before, you know,   we need years before we natal. And I just fell in love with this idea of medicine of the root cause. And once you learn it, you can't unlearn it. Like that's how you think about everything. It's like, even when, you know, your child has a tantrum nowadays, you're like, okay, like it's not them. Is it there? Is it that they're tired? Is it that they're hungry? Is it that they had sugar? You know, you, you   Michelle (06:27) you   Bye.   Ronit Menashe (06:35) learn about root cause medicine, you realize it, you know, that just everything is connected. And so for me, that was, you know, a big change in my career because I was focused more on marketing. And then I wanted to get into the functional medicine space. I took Chris Kresser's adapt course and, know, kind of started to learn about becoming a practitioner, but   it ended up serving me very well when I met Dr. Mark Hyman and I worked on his private practice and worked on his private practice more from like operations. And then I worked with him on his book launches. So still kind of like in the business side of things, marketing side of things, but more focused on this space that I love so much, which is functional integrative medicine.   Michelle (07:26) That's amazing. so I'm sure with that background, and also realizing that there is a need for this. It really inspired you to do, to have this supplement company.   Ronit Menashe (07:38) 100%. We spoke to Dr. Hyman when we first came up with the idea and he said, I always treat the man when a woman comes to me with infertility. And so what we wanted to do with WeNatal is be able to give everybody access to this kind of functional medicine approach, which essentially means optimizing male fertility and female fertility before trying to conceive.   what it looks like is nourishing your body and kind of, creating that optimal soil for conception. And, know, we always say when you improve your health, you're improving your fertility. And when you're improving your fertility, you're improving your health. And we hear from so many customers that, you know, let's say men, for instance, they're taking we natal for him. And all of a sudden they have a libido all of a sudden.   They have energy, they focus, their hair is growing. So that's kind of the side effects and the byproduct of working on improving your sperm and egg quality is you actually also feel good when you're nourished. You feel good when you're depleted from nutrients. Of course, you're going to be tired. And so many people just accept   this notion of like, I'm getting older so I should be tired or I'm getting older I should be losing my hair or I'm postpartum I should be   Michelle (09:06) Like it's normal,   normal versus common.   Vida Delrahim (09:08) Exactly.   Exactly.   Ronit Menashe (09:09) Exactly. Exactly. So   yes, these things are common, but they're not normal. And Vida and I just, you know, had this like life circumstance where we realized like it's our mission now to educate people on the importance of preconception, that there is so much you could do as a couple. He needs to be part of the equation. And when we started WeNatal, we didn't know if the men would be into it, but we're happy to say   Our we-natal men are amazing. We have so many incredible couples that are doing this together from day one. And we're always saying like, they're gonna be the best dads. If they are participating in fertility so early, they are amazing parents already.   Michelle (09:56) So yeah, for sure. And talk about like the different ingredients or the and what they do when it comes to both egg and sperm quality. And you can take your time on this   Ronit Menashe (10:08) for sure. Well, you know, here's the thing. We didn't think that the world needed another prenatal for women because there are so many prenatals out there, thousands. know, and. But when we started to dive into it and particularly for us, we were taking these packets made out of plastic that had seven pills in them.   And we just thought women deserve better. Why do they need to take seven pills? Why do they need to throw out plastic every day? Like we care about creating these healthy little humans. What about the environment? there was that. Then when we looked at the lower level prenatals, we noticed that a lot of the ingredients were not bioavailable. So what does that mean?   not everybody could utilize the nutrients that are part of those prenatals. So let's use folic acid as an example. When a prenatal has folic acid, that is the synthetic form of folate, which a lot of prenatals on the market, like if you go to a CVS or a Target, they have folic acid. And if somebody has the MTHFR genetic mutation,   They cannot utilize that folic acid. And so that nutrient is actually harmful to them. So for we natal, all of our nutrients are bioavailable. They're all in the methylated B form. like methyl folate or 5MTHF. So first of all, we have bioavailability. Second of all, comprehensiveness.   A lot of the prenatals on the market have 12-ish ingredients. We have 24 nutrients and we wouldn't leave one nutrient out. And it's very important because each and every one of our nutrients that are in our prenatal serves a very specific purpose for mom and baby and health of the pregnancy. And then you have...   dosages because even if something has 24 key ingredients like we natal the Dosages make a big difference. So using choline as an example choline We natal has 400 milligrams choline is crucial for baby brain development and the research shows that a pregnant woman needs 450 milligrams and a lactating woman needs 550 milligrams the average   Choline intake in the American diet, which you get choline from egg yolks is around 180. So we natal has 400 to be able to support that postpartum mom and obviously the pregnant mom, but there are prenatals on the market that have 50 milligrams. Now this is crucial for cognition of baby, brain mass, baby brain development.   Michelle (13:15) Mm-hmm.   Ronit Menashe (13:22) And so we were like, we have to create a prenatal for us because what we were doing is we were taking that base prenatal. We were adding choline. We were adding vitamin D. We were adding folate. We were adding iron. And most women are not going to do that. Most women are not going to, you know, take 10 plus pills a day and spend all that money on   all of these nutrients. We were doing it because we were immersed in the research and we saw how important these nutrients were. But we wanted to create a product that made it simple and easy for women and men to take their prenatal. Our packaging is beautiful and the reason is, well, first of all, we love nice things, but also,   Michelle (14:15) Thank   Ronit Menashe (14:16) We   wanted it to be part of people's home, people's life. So they're not hiding their prenatals in their, you know, cabinets that they can take it every day because consistency, like everything in health and wellness, consistency is what's going to make the biggest difference. And so that's kind of from a high level. And then, you know, you asked me what's in the prenatal and we can geek out a little bit more on the nutrients and what they do.   But what's not in the prenatal is also a big, big key because a lot of supplements on the market have a ton of additional ingredients and those ingredients are harmful for fertility and just overall health. And so it's important. We always say it's important to look at the nutrition facts.   but also look underneath the nutrition facts like what else is in there that shouldn't be in there and we natal doesn't have any additional fillers. And we do that because we manufacture in smaller dosages. We're not manufacturing in mass. Our shelf life is only two years where it's not like some prenatals that their shelf life is forever.   which, you know, for us, we're fine. We're doing things in smaller batches. And, you know, from a business perspective, it complicates things, definitely complicates Vida's life because she's on the operation side of things, but we're doing the right thing for the consumer. And that's what matters to us the most.   Michelle (15:43) .   So I know that like for my patients, for example, I'll give them certain supplements, preparing, including a prenatal, but then I'll also add more supplements that I don't necessarily have them continue taking after they're pregnant. So some that are more like to beef up the quality of the eggs. Do you guys have different ones or is it like certain? Yeah.   Vida Delrahim (16:13) Mm-hmm.   Ronit Menashe (16:16) Yes.   Yes. So we have our foundation support, which is the prenatal for him and for her. That is the multivitamin for men slash sperm support. And for women, it's the prenatal that has key nutrients for before, during, and after. But for those who want to beef up their egg quality, and we could talk about the scenarios in which you would need this product or not.   Michelle (16:35) Mm-hmm.   Ronit Menashe (16:44) We have a product that we launched this year called Egg Quality Plus, and it's five nutrients in one. So it's the five nutrients that we were taking after our miscarriage, CoQ10, NAC, PQQ, alpha lipoic acid, and L-carnitine. And what these nutrients do is they help improve egg quality. How do they do it?   Michelle (16:49) Mm-hmm.   Mm-hmm.   Ronit Menashe (17:12) These nutrients are very specific nutrients that help improve mitochondria. We know that the three months before you ovulate, the egg that you ovulate with is going through all these processes that are very complex that require very strong mitochondria. So your mitochondria is like the battery of the cell. And if the battery is low,   that process is not gonna go well and you're gonna end up with chromosomal abnormalities. So it's important to quote unquote charge the battery before you start trying so that when that process does take place, it happens with no or limited errors, if that makes sense. So we recommend for women who are either older or maybe had recurrent miscarriages or   Michelle (18:00) Yeah.   Ronit Menashe (18:09) Just wanna know that they did everything possible in the preconception timeframe to take Egg Quality Plus with our prenatal, which the prenatal also includes nutrients that help improve egg quality like folate, vitamin D. By the way, 4,000 I use a vitamin D. I don't think any prenatals on the market have that. And then, you you talked about in the postpartum phase, like for us,   what was very important to include in our prenatal is iron because in the postpartum phase and in third trimester, a lot of women are very depleted from nutrients because you require more iron in that timeframe and just to help with postpartum recovery and all of those things. So our prenatal has iron in it as well.   So what we wanted to do with the prenatal is be able to simplify people's lives and give them a tool that they can use before, during, and after. Then if somebody wants that extra boost, they could get that Egg Quality Plus B4. And that's kind of the philosophy. We wanna make it simple and easy. And the other thing that I didn't mention is our prenatal dosage is three pills a day. And so...   Michelle (19:13) Mm-hmm.   Mm-hmm.   Mm   Ronit Menashe (19:31) We just don't think it's realistic to ask women to take eight pills plus per day for their prenatal, especially in their first trimester when they're nauseous and they're throwing up and they can barely stomach any food.   Michelle (19:41) Yep. yeah, for sure.   And then as far as the iron, I know there's many different forms of iron and some can cause constipation. So I just wanted to ask about that.   Ronit Menashe (19:53) Yeah, so the forms, we didn't get into the like real geekiness of our forms, but every single one of our forms are the best form that we can find. And we use a patented iron that doesn't constipate called ferrochell. And we do the same with some of our other ingredients, like our choline is microencapsulated. Every, our selenium is this like super special selenium.   Every single one of our nutrients is sourced from the best of the best because we feel like women deserve the best. This is such an important time in people's lives and the nutrients really make a big difference and can make or break your journey.   Michelle (20:43) I love that. I love that you're really putting attention to detail because it does make such a difference. And the thing is the thing, the reason why I'm asking also is just from my perspective as a practitioner, I'm always looking for supplements that can address so many issues. And what I find myself doing is getting a bunch of different things and then having to give so many different supplements and so many different bottles. So I love the fact that you guys have   this really like thought out. It's really nice.   Vida Delrahim (21:16) Well, that's essentially what   Ronit was doing with me when we were on this journey together. She was AKA my doctor. And she's like, look at all the research shows that you need add iron you add this and so it ended up being I don't know Roni at some point I swear it was like 1215 maybe capsules because of all the additions some of it was drops. I could not keep up Ronit was a champion at taking supplements she could like down 10 at a time. I was nursing a couple meal   Michelle (21:41) Yeah.   Vida Delrahim (21:43) And of course   I wouldn't even comply. And so that was when also the idea of we need to like the ease and simplicity is so important. We're all busy, but we want to know that we're giving our body the best nutrients. I had guilt about not taking enough because I literally just couldn't down pills as quickly as some people can. And so the fact that we're able to get these 24 quality bioavailable ingredients into three capsules took us years. And we're so proud of that because it is the nutrient density of six to eight capsules in three.   And so that's what we were doing. We realized it wasn't feasible for everybody. Not everyone is at a road who can just chug them along. We realized this world had to be reinvented.   Michelle (22:23) yeah, for sure. Well, this is great. mean, lots of great information. I'm looking at your website right now, actually. Yeah, you guys definitely, it looks like you guys did a lot of research and you also have a blog, which is great. Cause I think it's so important to educate people that are on this journey.   Ronit Menashe (22:44) Well, that is exactly what we didn't have. It's so hard to reliable information that you can trust. And so we have an amazing blog and we put out so much great content on literally any topic under the sun from what to do if you just got diagnosed with gestational diabetes to, okay, how do you create a clean nursery to you know how to you know the fertility crisis you know we span everything on the blog and we share about it in our newsletter and we have an amazing guide with nine preconception tips if your listeners want to go to we natal.com slash guide they get our free couples guide and it's a really great starting point and a lot of the things that couples could do to support their fertility is free it doesn't have to be like   complicated or fancy. It's a lot of like free things. And so that guide is a really great resource.   Michelle (23:50) Awesome. Well, this is great information and you guys, this isn't a sponsored episode. It really is me wanting to find out more because there are amazing new things out there. And I think that it's important to hear all the different perspectives and really get it from the founders. So thank you guys so much for coming on and for people who are looking to learn more, how can they find you guys?   Ronit Menashe (24:19) They on we natal.com our website on social. We're very active and that's where we also share a lot of the new research at we underscore natal. And also we're happy to hear from your listeners. Anybody has questions or needs help or needs us to point them in the direction of some something or some article they can DM us at our, on our Instagram where we're most active.   Michelle (24:49) Awesome. Well, I loved this conversation and I loved all the details and the nerdy aspects of it because for me, I really liked the breakdown. think one thing that I find is that you want to find the smartest audience. It's usually a fertility audience. They're so smart because they do so much research on their own health and they really look into much more than the doctors give them. so,   So I know that they like to find out really detailed information. So thank you for that. And thank you so much for coming on today.   Vida Delrahim (25:26) Thanks for having us. We're excited to support you and your community.   Michelle (25:31) Awesome.   Ronit Menashe (25:31) Thanks, Michelle.  

Optimize Cellular Health for Longevity, Fat Metabolism & Performance To improve body composition, metabolic efficiency, and longevity at the cellular level, focus on mitochondrial function, gut health, inflammation control, and metabolic flexibility.  Optimizing Fat Oxidation & Mitochondrial Function as You Age

This special 2 hour Christmas Day episode of Joe Cannon Health is packed with insights, answers, and companionship for anyone spending the holidays alone. Tune in as we explore fascinating topics, including: Autophagy: What it is and how to boost it naturally. Vitamin K: A surprising remedy for leg cramps. Kimchi: Can it really promote hair growth? Nattokinase: Its role in heart health and circulation. PQQ: The connection between this compound and memory improvement. Nutrafol: Are there hidden risks, like liver problems? Rhabdomyolysis: What you need to know about this serious condition. Xylitol: Is there a link to heart attacks? Vinegar and Depression: Examining the evidence behind this intriguing claim. AND MORE!! Whether you're here to learn, find inspiration, or simply spend time with a friendly voice, this episode is for you. Let's celebrate the season with curiosity, compassion, and a commitment to better health. autophagy, Vitamin K for leg cramps, Kimchi for hair growth, nattokinase benefits, PQQ memory support, Nutrafol side effects, rhabdomyolysis education, xylitol heart attack risk, vinegar for depression, Christmas health podcast, holiday wellness tips, natural remedies, health myths debunked.    Supplement Facts Coffee Mug: https://joecannon.creator-spring.com/listing/supplement-facts-mug   Consultations  https://supplementclarity.com/private-consultations/     Get My Rhabdo Book   Education is the best defense against getting rhabdomyolysis. I've been teaching about rhabdo for over 10 years. If you are in the US, you can order my book directly from me. Purchase My Rhabdo Book Order on Amazon      Connect With Me Joe-Cannon.com SupplementClarity.com YouTube     About Me   For over 30 years, I've been sorting nutrition facts from fiction, busting myths and helping people understand dietary supplements using clinical research as my litmus test.    I have an MS in exercise science and a BS in biology & chemistry. I've written several books, including Rhabdo, the first book about exercise-induced rhabdomyolysis.   Disclaimer   Episodes are for information only. I'm NOT a medical doctor. NO medical advice is given or implied. ALWAYS consult your physician for the best health advice for you. I participate in the Amazon Associates program which means if you click on a link to amazon and make a purchase, I may make a small commission at no extra cost to you.    

Get more Aliquots! Become an FMF Premium Member and get full access to our members-only podcast, The Aliquot, plus live Q&As with Rhonda, every-other-week Science Digest emails, and more.   Learn more about The Aliquot podcast here Vitamins are substances that our bodies need to develop and function normally. When considering vitamins, we tend to think of the usual suspects – A, C, D, E, and K, plus the eight B vitamins. However, the body produces many molecules that fit the description of a vitamin, driving physiological processes from infancy through later life. Some of these molecules might even be considered longevity "vitamins" – substances that extend healthspan and promote a longer life. In this Aliquot, I talk about three substances that may act as longevity vitamins – taurine, ergothioneine, and PQQ. This episode includes several key discussion points:   (03:09) Is taurine the key to Okinawan's long lifespans? (04:49) How taurine promotes mitochondrial health (06:05) How taurine deficiency impacts muscle mass (06:41) Does supplementing the age-related decline boost longevity? (08:58) Okinawa's High Intake vs. Japanese in Brazil (10:01) Blood pressure, blood lipids, and glucose levels (13:07) The role of ergothioneine in shielding membranes from oxidative damage (15:14) How ergothioneine's unique lipophilic properties protect mitochondria (19:18) Why some people transport ergothioneine better than others (20:17) Whether to get ergothioneine from foods or supplements (24:18) Is ergothioneine destroyed by cooking? (25:02) The unusual antioxidant power of PQQ (26:21) The role of PQQ in the brain (29:12) PQQ's impact on NAD and sirtuin levels? (30:37) Does PQQ blunt the positive effects of exercise?   For a deeper foray into this special topic, I highly recommend reading Dr. Bruce Ames' seminal paper, Prolonging healthy aging: longevity vitamins and proteins, published in the Proceedings of the National Academy of Sciences. This open-access article explores a range of compounds, including taurine, PQQ, and ergothioneine, which Dr. Ames identifies as potential longevity vitamins. The study provides valuable insights into how these vitamins and proteins could contribute to extending healthy lifespan.   This episode features segments taken from several Q&As with Dr. Rhonda Patrick. You may view these episodes and their show notes here:   Q&A #7 with Dr. Rhonda Patrick (1/4/20) Q&A #12 with Dr. Rhonda Patrick (6/6/20) Q&A #44 with Dr. Rhonda Patrick (2/4/23) Q&A #50 with Dr. Rhonda Patrick (8/5/23) Q&A #53 with Dr. Rhonda Patrick (11/4/23) Q&A #54 with Dr. Rhonda Patrick (12/2/23)

In this episode, we explore the research behind SS-31 peptide and other supplements as possible groundbreaking interventions for mitochondrial dysfunction, shedding light on their mechanisms as detailed in the scientific literature. We delve into the concept of the mitophagy stack, presenting it as a superior alternative to "Urolithin a" alone, for enhancing the clearance of damaged mitochondria and rejuvenating cellular energy production. Furthermore, we unravel the complex relationship between mitochondrial dysfunction and chronic fatigue, elucidating how impaired energy production at the cellular level can lead to pervasive fatigue and compromised quality of life. Topics: Introduction to Mitochondrial Dysfunction Chronic illnesses and their relation to mitochondrial dysfunction Examples: Chronic Fatigue, Chronic Inflammatory Response Syndrome, Lyme Disease, Candida Overgrowth... Importance of understanding mitochondrial dysfunction on a large scale and biochemical level Understanding Mitochondrial Dysfunction Definition and general overview Underlying causes: Genetic mutations, environmental stressors, toxins, aging Biochemical pathways involved: Oxidative phosphorylation, reactive oxygen species (ROS) generation, calcium homeostasis, apoptosis Oxidative Phosphorylation and Dysfunction Role in ATP production Components: Electron Transport Chain (ETC) and ATP Synthase Dysfunctional aspects due to genetic mutations and aging Vicious cycle of mitochondrial DNA mutations, decreased ATP production, and increased ROS Factors Contributing to Mitochondrial Dysfunction Genetic mutations (mtDNA and nDNA) Aging and its impact on mtDNA Environmental toxins and stressors (e.g., psychological stress, radiation, biotoxins, toxicants, nutrient deficiency) Nuclear DNA alterations Mitophagy and Mitochondrial Biogenesis Importance of removing old and damaged mitochondria Role of urolithin a and its enhancement with EGCG in mitophagy Supporting biogenesis: PQQ, resveratrol, EGCG, anthocyanins, curcumin, glycyrrhizic acid, salidroside Supplements and Nutrients for Supporting Mitochondrial Function Clinical trials and effective supplements: L-carnitine, α-lipoic acid, CoQ10, NAD precursors, membrane phospholipids Peptide Therapy for Mitochondrial Dysfunction Introduction to SS-31 peptide Mechanism: Binding to cardiolipin for efficient oxidative phosphorylation Potential for stimulating mitochondrial biogenesis Conclusion and Reminder Only ever work with a medical professional. Thanks for tuning in! Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" If you liked this episode, please leave a rating and review or share it to your stories over on Instagram. If you tag @synthesisofwellness, Chloe would love to personally thank you for listening! Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Follow Chloe on TikTok @chloe_c_porter Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to purchase products, subscribe to our mailing list, and more! Or visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠linktr.ee/synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to see all of Chloe's links, schedule a BioPhotonic Scanner consult with Chloe, or support the show! Thanks again for tuning in! --- Support this podcast: https://podcasters.spotify.com/pod/show/chloe-porter6/support

Dive into the essence of lasting health transformations with Carly Pollack, a certified clinical nutritionist with a depth of knowledge in wellness. This episode goes beyond mere goal-setting to redefine our approach to health. Carly offers insights into tuning into our body's signals and establishing a health regimen that transcends the calendar year. She shares humorous and practical tips for boosting mitochondrial health, including her use of PQQ supplements—blue tongue and all. Tackling the challenges of a healthy lifestyle, particularly against the backdrop of perfectionism and unsupportive settings, is at the forefront of our discussion. Carly illuminates the path to full accountability for our health decisions. We explore building resilience, fostering self-kindness, and devising backup plans to maintain progress, even when obstacles arise. For those grappling with perfectionism, Carly emphasizes the transformative power of viewing setbacks as opportunities for growth and learning. Our conversation extends to tangible wellness tactics that enhance your life and are economically feasible. We dissect the impacts of sleep and caffeine on cravings. The dialogue concludes by advocating for a comprehensive wellness model that integrates movement, hydration, nutrition, sleep, and mental health as key to optimal health. Tune in for an enlightening exchange with Carly Pollack, guiding us towards thriving health through a blend of personal stories, theoretical knowledge, and practical strategies tailored for functional medicine providers and patients.Chapters:(04:29) Creating Lasting Change(20:03) Creating a Healthy Lifestyle(27:01) The Complexity of Perfectionism and Self-Reflection(34:49) Aligning Goals, Needs, and Values(44:43) Sleep, Caffeine, Health, Cravings(53:23) The Importance of Comprehensive Health Approach(59:37) Importance of Foundations in Health(01:06:29) Promoting Vibrant Health and WellnessLinks:CarlyPollack.comNutritionalwisdom.comJoin Over 18,000 Leading Medical Professionals and Become a Vibrant Wellness Provider Today!

In this podcast, we're going to talk about the importance of mitochondria in relation to longevity and how specific molecules found in food can help support their function. We explore the benefits of PQQ, polyphenols, Coenzyme Q10, L-carnitine, carnosine, phycocyanin, and EPA/DHA. These molecules are found in a variety of foods, such as: • Cacao, which contains PQQ • Berries, grass-fed meats, and cheese, which are rich in polyphenols • Liver, red meat, and fatty fish, which are good sources of Coenzyme Q10 • Red meat, which is high in L-carnitine and carnosine • Spirulina, which is a vegetarian source of phycocyanin • Salmon, sardines, and cod liver oil, which are rich in EPA and DHA Incorporating these foods into your diet can potentially increase the number of mitochondria in your cells, improve energy production, decrease oxidative stress and inflammation, and slow down aging. Let's dive deeper into each of these potent molecules and their specific benefits: • PQQ—Boosts mitochondrial count and supports uninterrupted energy production in cells. • Polyphenols—Enhance mitochondrial function and reduce inflammation. • Coenzyme Q10—Is essential for proper mitochondrial functioning, especially in energy production. It also acts as an antioxidant and may have therapeutic effects for mitochondrial diseases. Supplementing with Coenzyme Q10 may benefit those taking statins. • L-carnitine—Helps with fat burning, muscle preservation during exercise, and post-workout recovery. • Carnosine—Acts as a pH buffer, reducing inflammation and oxidative stress, and may delay aging. • Phycocyanin—Has antioxidant properties and supports mitochondrial biogenesis, increasing energy production and potentially protecting DNA. • EPA and DHA—Are omega-3 fatty acids that increase mitochondrial function, reduce oxidative stress, have anti-inflammatory effects, and improve insulin sensitivity. DATA: https://www.ncbi.nlm.nih.gov/pmc/arti...

1. Women's Hair loss? Zinc, Choline, Biotin 2. Memory Loss? PQQ, Biotin, Lithium, Thiamine 3. Low Testosterone in Men and Premenopausal Women? Zinc, Arginine, Carnitine, B12 4. Fibromyalgia? Boron, Molybdenum, Glutathione, Copper, Zinc 5. Hypothyroidism? Zinc, Selenium, Iodine 6. Insulin Receptor Dysfunction Zinc, B12, Chromium, Selenium, Omega 3 EPA and DHA 7. POTS? Iron, CoQ10, B12, Folate Pyridoxine B6 8. Migraines? Boron, Molybdenum, Zinc, B12, Glutathione 9. Osteoporosis? Calcium, D3, Zinc, Magnesium, K1, K2 10. Lower Blood Pressure? Theanine, Arginine, Citrulline

Guest: Hiatt My name is Aaron Hiatt. I have been in the HTMA field for about 10 years now and have analyzed over hundreds of hair tests. I originally got into hair analysis testing while in college after battling some health issues. I have experienced a lot of health improvements following the teachings of Dr. Paul Eck and Dr. Wilson Lawrence. I continue to expand my own understanding and knowledge across many areas of research concerning the human body.    Website: https://redoxstasis.com/store/arl-hair-analysis-test-kit?fbclid=PAAabxbLL7bDkK7-BxfRCVhZFeVzxpSJpqjKA4eAzwJV5oHUVZi1JkHFh8Za0    Valence Nutraceuticals: Use code ITP20 for 20% off https://valencenutraceuticals.myshopify.com/   Summary This conversation explores the importance of mineral balancing and the benefits of mineral orotates, with a focus on the work of Dr. Hans Nieper and Dr. Paul Eck. The chapters cover topics such as the science behind mineral orotates, the difference between orotates and amino acid chelates, the improvements in mineral supplements, and the legacy of Dr. Paul Eck. The conversation also discusses the dosage and absorption of magnesium orotate, the continued research and development in supplement formulations, and the importance of collaboration and improvement in the field. This conversation covers various topics related to the utilization and benefits of different vitamins and minerals. The chapters include discussions on the impact of alkaline phosphatase on B6 utilization, the comparison of active B complex supplements, the importance of manganese for thiamine utilization, the benefits of a community-based healthcare system, the effectiveness of bioavailable forms of vitamins, the advantages of tocotrienols over tocopherols, research on tocotrienols in Russia and Germany, the superior antioxidant potential of tocotrienols, the research on potassium orotate, the anxiolytic effect of potassium orotate, the difference between folate and folic acid, the ratio of adenosylcobalamin to methylcobalamin in meat, the benefits of adenosylcobalamin over methylcobalamin, the superior absorption of selenoxale, the benefits of methyl selenocysteine, the role of selenoxale in circadian rhythm, gender differences in selenium supplementation, the benefits of chromium picolinate, the comparison of chromium polynicotinate and chromium picolinate, the impact of chromium on PCOS, and the benefits of PQQ for mitochondrial health.   Chapters 00:00 Introduction and Background 03:09 The Importance of Mineral Balancing 14:53 Mineral Orotates and Dr. Hans Nieper 21:11 The Science Behind Mineral Orotates 32:54 The Difference Between Mineral Orotates and Amino Acid Chelates 38:05 Improvements in Mineral Supplements 41:47 The Benefits of Magnesium Orotate 44:17 Dosage and Absorption of Magnesium Orotate 51:28 Continued Research and Development 54:08 The Legacy of Dr. Paul Eck 59:17 Updates in Supplement Formulations 01:05:15 Collaboration and Improvement 01:08:16 The Importance of P5P in B6 Supplementation 01:13:06 Impact of Alkaline Phosphatase on B6 Utilization 01:14:27 Comparison of Active B Complex Supplements 01:15:36 Importance of Manganese for Thiamine Utilization 01:16:11 Benefits of Community-Based Healthcare System 01:17:12 Effectiveness of Bioavailable Forms of Vitamins 01:18:47 Advantages of Tocotrienols over Tocopherols 01:19:12 Research on Tocotrienols in Russia and Germany 01:20:41 Superior Antioxidant Potential of Tocotrienols 01:21:29 Research on Tocopherol vs Tocotrienol 01:21:56 Personal Experience with Tocotrienols 01:22:49 Research on Potassium Orotate 01:23:39 Research on Potassium Orotate in Russia and Germany 01:24:38 Anxiolytic Effect of Potassium Orotate 01:25:04 Effect of Adrenal Dysfunction on Potassium Levels 01:25:43 Comparison of Potassium Orotate and Potassium Aspartate 01:26:59 Reason for Using Potassium Orotate in Slow Oxidizers 01:27:38 Benefits of Methyl Tetrahydrofolate (5-MTHF) 01:28:37 Dangers of Synthetic Folic Acid 01:29:17 Difference Between Folate and Folic Acid 01:30:31 Ratio of Adenosylcobalamin to Methylcobalamin in Meat 01:31:53 Advantages of Adenosylcobalamin over Methylcobalamin 01:33:43 Superior Absorption of Selenoxale 01:34:13 Benefits of Methyl Selenocysteine 01:35:09 Role of Selenoxale in Circadian Rhythm 01:36:20 Gender Differences in Selenium Supplementation 01:37:41 Benefits of Chromium Picolinate 01:38:37 Comparison of Chromium Polynicotinate and Chromium Picolinate 01:40:21 Impact of Chromium on PCOS 01:41:43 Benefits of PQQ for Mitochondrial Health     Advertisements:   Valence Nutraceuticals: Use code ITP20 for 20% off https://valencenutraceuticals.myshopify.com/   Zeolite Labs Zeocharge: Use Code ITP for 10% off https://www.zeolitelabs.com/product-page/zeocharge?ref=ITP Magnesium Breakthrough: Use Code integrativethoughts10 for 10% OFF https://bioptimizers.com/shop/products/magnesium-breakthrough Just Thrive: Use Code ITP15 for 15% off https://justthrivehealth.com/discount/ITP15 Therasage: Use Code Coffman10 for 10% off https://www.therasage.com/discount/COFFMAN10?rfsn=6763480.4aed7f&utm_source=refersion&utm_medium=affiliate&utm_campaign=6763480.4aed7f Nootopia: Use Code IntegrativeThoughts10 for 10% OFF https://nootopia.com/ Sleep Breakthrough: Use Code IntegrativeThoughts10 for 10% OFF https://bioptimizers.com/shop/products/sleep-breakthrough Matt Coffman / Integrative Thoughts My Instagram: @integrativematt My Website: Integrativethoughts.com  

Today's episode shines a light on a new supplement making its way into the fertility landscape. Pyrroloquinoline quinone, otherwise known as PQQ, is a redox cofactor that has been shown to stimulate the growth of new mitochondria, the cellular powerhouse where nutrients are turned into a form of energy cells can use. It is in essence, a very powerful antioxidant.  Whereas CoQ10 energizes the mitochondria, PQQ can actually help create NEW ones. This is major in reversing the effects of aging and oxidative stress. The development of sperm and egg cells is a highly complex and energy-dependent process that is supported by and requires a diverse array of micronutrients, which decline as we age and continue to consume poor-quality food. PQQ has been found to improve cell functions by stimulating growth, reducing oxidative stress (protecting cells from damage) as well as spontaneous generation of new mitochondria within aging cells.You may know that a fertility-friendly diet, eliminating smoking, minimizing alcohol, reducing stress, and engaging in fertility-friendly exercise is very important when trying to conceive, but we also know that fertility-specific supplements can be powerful allies in the fertility journey. Catered "nutraceuticals" can help you fill in nutritional gaps and provide other nutrients that are difficult to get through diet alone. Could this supplement be right for you? Tune in to get the scoop.You'll Learn: Research supporting PQQ's benefits in fertility outcomes What PQQ is and how it can be supplementedThe correlation between the mitochondria and sperm/egg qualityThanks so much for listening to our podcast! If you enjoyed this episode and think others would love to hear it, please share it using the social media buttons on this page. Do you have some feedback or questions about this episode or want to be a guest on the show? Leave a comment in the section below or visit the website to contact me!www.naturnalife.comSubscribing to The Podcast:If you would like to get automatic updates of new podcast episodes, you can subscribe to the podcast on Apple Podcasts, Stitcher, Spotify, Amazon, or whatever your favorite podcast app is!Ratings and reviews from our listeners are extremely valuable to us and greatly appreciated. They help our podcast rank higher on Apple Podcasts, which exposes our show to more awesome listeners like you. So if you have a minute, please leave a review on Apple Podcasts! 

The immune system is complex, and there is a lot of research on how different nutrients impact it. Before you buy any supplements, please make sure you are already prioritizing covering the basics, including eating healthy, sleep, hydration, and exercise. No amount of immune-boosting supplements or superfoods will make up for the basics you need to keep your immune system running effectively. If you have these basics in place, you may want to consider additional supplements to boost your immune system.   This episode is an overview of the risks, benefits, safety, and evidence available on the ability of many vitamins, herbs, and supplements to boost your immune system during pregnancy. I could easily do an entire episode on each of the immune-boosting supplements covered here, including folate and folic acid, vitamins A, C, D, E, zinc, selenium, antioxidants, glutathione, PQQ, herbal immune support, echinacea, elderberry, probiotics, mushrooms, and choline. As always, please talk to your doctor or midwife about any supplements you consider. That includes any herbs or over-the-counter vitamins or supplements.   Thank you to our sponsors   Dental.com's AI Smart Scan is absolutely free, super easy to use, and provides essential information about oral health during pregnancy. Did you know your oral health also plays a vital role in your baby's well-being? Maintaining good oral health can prevent you from passing the harmful bacteria that cause cavities to your newborn. That's right, it could mean the difference between your child having a lifetime of battling decay vs. no decay at all. Your baby deserves the best, and so do you. Visit dental.com and try the Smart Scan today. It's a little effort with a whole lot of reward.   Skylight allows you to instantly get all of the amazing baby pictures off your phone and display them in a beautiful frame in your home. A Skylight Frame is the best thing to give yourself or a family member to bring constant joy. Skylight has over a million happy customers and thousands of 5-star reviews. They are confident you will love this frame and offer free 120-day returns. As a special, limited-time offer for our listeners, get $15 off your purchase of a Skylight Frame when you go to SkylightFrame.com/PREGNANCYPOD.   The VTech V-Hush Pro Baby Sleep Soother has every feature you could possibly want to transform any room into a sleep sanctuary. Create ideal sleep patterns and environments for your baby, so your whole family gets better and longer sleep. The V-Hush Pro has built-in sleep programs and sleep tips from WeeSleep experts, over 200 pre-programmed stories, classical music, lullabies, and natural sounds. You can even record and upload your own voice, songs, or stories using the subscription-free app. The VTech V-Hush Pro Baby Sleep Soother is available at Walmart and Amazon.   Read the full article and resources that accompany this episode.   Join Pregnancy Podcast Premium to access the entire back catalog, listen to all episodes ad-free, get a copy of the Your Birth Plan Book, and more.   Check out the 40 Weeks podcast to learn how your baby grows each week and what is happening in your body. Plus, get a heads up on what to expect at your prenatal appointments and a tip for dads and partners.   For more evidence-based information, visit the Pregnancy Podcast website. https://pregnancypodcast.com 

In this episode of the Smarter Not Harder podcast, we are joined by the father of Biohacking, Dave Asprey. He educates us on the laziness principle and how to utilize it to our advantage, exposomics and epigenetics, and if spirituality can be hacked.   Dave Asprey is a four-time New York Times bestselling science author, the creator of the Bulletproof Coffee, the founder of the Bulletproof Company, and is also known as “the Father of Biohacking”.   He attended  University of California, Santa Barbara and majored in computer science and later earned his undergraduate degree in computer information systems from California State University, Stanislaus. He then earned his MBA from Wharton. He is also the host of the Webby award-winning podcast “The Human Upgrade with Dave Asprey” and has been featured in different outlets such as Men's Health, Wired, the Joe Rogan Experience, CNN, and more.   What we discuss:   00:00:31 - About Dave Asprey 00:05:15 - About Dave's book, “Smarter Not Harder” 00:05:55 - How can laziness make us strong? 00:10:57 - Why the body wants to conserve energy rather than using it 00:12:55 - How does one cheat the spike? 00:19:47 - How does it become an inside job? 00:25:35 - What is exposome and what's glyphosate got to do with it? 00:27:22 - What are lectins and why should we avoid them? 00:34:35 - More about Vitamin D  00:42:42 - Why mitochondria is focused on in his book?  00:45:21 - What are omega six fatty acids and why are they a double edged sword? 00:51:16 - What is PQQ and what does it do? 00:52:25 - Does PQQ affects the ratio of cardiolipins in the mitochondria?  00:53:44 - How does a pulsed EMF affect your energy level and metabolism? 00:56:32 - What is HUSO? 01:00:32 - How do we hack the epigenome and what does the test that measures ones' epigenetic age do? 01:04:54 - Dave's opinion on 3D printed meat 01:05:01 - How did coming to terms with emotions help Dave in his divorce? 01:10:12 - Why is equanimity the highest spiritual target?  01:12:26 - Dave's top 3 Smarter Not Harder hacks to live a happy life 01:14:45 - Dave's take on psychedelics     Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg   Find out more about Dave Asprey: Website: https://daveasprey.com/ Podcast: https://daveasprey.com/category/podcasts/ Smarter Not Harder by Dave Asprey: https://www.amazon.com/Smarter-Not-Harder-Biohackers-Getting-ebook/dp/B0B399L6KP?ref_=ast_author_dp Other Books: https://daveasprey.com/books/ Twitter: @bulletproofexec Instagram: @dave.asprey LinkedIn: https://www.linkedin.com/in/asprey/ Facebook: https://www.facebook.com/Daveaspreyofficial/   Get 10% Off Your Purchase of Metabolomics Module by using PODCAST10 at https://www.homehope.org   Get 10% Off your Trosciptions purchase by using POD10 at https://www.troscriptions.com   Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram. 

TD and Matt from The Texas Boys join the podcast today to discuss their journey from the Northeast to Texas, and how their lives have changed since. After 8 years of living in the country of Texas, their family has developed an in-depth understanding of farming – and a knack for self-sufficiency.  A stark contrast from the hustle and bustle of the Northeast, this fresh lifestyle has enabled them to live the meaningful lives they had always dreamt of…   From leather goods to coffee, The Texas Boys offer their audience a vast array of products and education. What is their mission in all of this? To be self-sustainable with the help of their community.  Offer: Do you struggle with a lack of focus or energy? The team at Physician Designed knows the feeling and they can help! Brain Support MicroPQQ® & MicroActiveCoQ10® uses a proprietary blend of PQQ and CoQ10, to maximize the boost you need without any negative side effects. Studies show that Brain Support MicroPQQ® & MicroActive® CoQ10 lowers fatigue, anxiety, and depression while increasing mental acuity and awareness. Feel the difference for yourself today! Save 30% on your next order at physiciandesigned.com using code GENIUS during checkout. Click play to learn more about: What made The Texas Boys want to move from the Northeast? How The Texas Boys dealt with an extreme weather event in 2020. The importance of being aligned with a community that fits your core values. To learn more about The Texas Boys, visit TheTexasBoys.com now! Episode also available on Apple Podcast: http://apple.co/30PvU9C