Medication
POPULARITY
You're at the end of your rope, so you head to the pharmacy for the help you so desperately need to sleep. But wait, you aren't sure if it's safe, if it works, and if there's a better way. Stay tuned to learn about the benefits, side effects, and risk of sleep aids. I'm Dr.Vickie Petz Kasper. If you're ready to take control of your health, you're in the right place. I'll give you practical steps to start your own journey toward better health because healthy looks great on you. This is episode 159, Sleeping Pills and Potions. What works and what doesn't. You know that poor sleep is associated with heart disease, cancer, diabetes, obesity, immune dysfunction, high blood pressure, anxiety, depression, fatigue, irritability, and good grief, I could go on and on. So, taking something to help you sleep sounds like a good idea, right? Today, we'll discuss what you need to know before you go and get a prescription, supplement, or over the counter sleeping aid. Look, we have to sleep. Our very lives and health depend on it. But the struggle is real. Insomnia is one of the most common symptoms people go to the doctor or health care provider for treatment. And what if I told you that good sleep is possible without medications? Well, it is. In fact, the first line treatment recommended to treat insomnia is not medication. The standard recommendation for managing insomnia is to eliminate things that go bump in the night and keep you awake. Or, to treat underlying diseases that disrupt sleep. It's not recommended to start with behavioral therapy or medications until these other things are maximized. Ha! But good luck with that. If you go to your primary care provider and you don't get a prescription, I'll buy you a cup of coffee and we can both stay awake. And, if you think you need to see a specialist, then you'll probably get to spend the night in a sleep lab hotel hooked up to a bunch of wires and you may get answers, like, a CPAP, and that's important if you have sleep apnea, but if not, you might not even hear from them. No wonder you're looking for a good solution to sleep. And though medications are not the first line recommendation, that is the topic of today's episode. So let's get to it. We're going to start with prescription medications, then we'll talk about over the counter medications and wrap up with supplements. There are three classes of drugs approved to treat insomnia. Benzodiazepine receptor agonist, histamine receptor antagonist, and melatonin receptor agonist. Listening to all that medical jargon may be sufficient to put you to sleep. But wait, let me explain. You'll understand more after we go to mini medical school today and learn about receptors. These are made up of proteins and they receive chemical signals that produce a response. Let me give you this analogy. You've got a lamp sitting on an end table, but it's not plugged in, so there's no light. And when you stick those two prongs into the socket, behold, now you can sit and read. And that's kind of how a receptor works. The plug fits into the plug in. So an agonist is like the plug. It fits. It turns it on. It lets the electricity flow. But, if you had a toddler in the house, you might want to plug in one of those little plastic things so he doesn't stick a butter knife in there and get shocked. So that would be an antagonist. Okay, now wake up and pay attention. We've got three classes of drugs to look at. Benzo receptor agonist and melatonin agonist. That plug in and histamine receptor antagonist that block the plugin. And then there's another category called other. We'll just call that the clapper, you know, clap, clap. And the light comes on, clap, clap, and the light goes off. There are eight drugs in the benzodiazepine receptor agonist family. And the first five are about my age, you know, born in the 60s. They are Estazolam, which is Prosom, Florazepam, which is Dalmane, Quamazepam, which is Doral, Temazepam, which is Restoril and Triazolam, which is Halcion. Now the millennials aren't benzos, but they're still benzo receptor agonist. And you know, this generation got way more complicated spelling their kids' names, so I'm probably gonna have to sound them out like a first grade teacher on the first day of school. Eszopiclone is Lunesta, Zaleplon is Sonata. Zolpidem is Ambien. Those older drugs are crankier and cause more dependence although Restoril is the nicest in the category. There are other benzos which are technically prescribed for anxiety and some people do use them to help them sleep. Do they work? Here's what the data says for the old guys. They help you fall asleep faster. A whole whopping 10 minutes faster. And they increase total sleep time by half an hour to an hour. That's it. What about risk? Well, they make you sleepy, which is kind of the point, but also they can make you dizzy, which can make you fall if you get up and go to the bathroom during the night. And if you mix them with opioids, the reaction can be fatal. Now, the younger guys function about as well as the older ones, but they have shorter half lives, so their effects don't wear out their welcome so much with daytime grogginess. And they aren't so deadly when socializing with opioids. But rarely, they do some bizarre things like compel you to shop or gamble in the middle of the night. All for 10 minutes faster to go to sleep and half hour to an hour longer sleeping. Okay, clap on, clap off, let's talk about the other drugs. These are dual orexin receptor antagonists. Affectionately known as D O R A or Dora. The first one is Suvarexant, which is called Belsomra. The next one is Derodorexant, which sounds a lot like deodorant to me, and that's exactly what I'm gonna call it because the brand name is Quviviq. And finally, there is Limboxerant, which has a really cool brand name, Dayvigo. What? You've never heard of any of these? Well, that's probably because they're slightly less effective than the other drugs. They help you go to sleep seven minutes faster. But the main side effect is sleepiness, and people generally say they slept better. The next topic in pharmacology class in mini medical school is the histamine antagonist. You know, the little plastic thing that goes in the wall socket so your toddler doesn't. Doxepin is a tricyclic antidepressant that functions this way, and even in low doses it causes the desirable effect of drowsiness. So, it's approved for the treatment of drowsiness deficit. Unfortunately, there are some drugs it doesn't play nice with. But, it does increase sleep time by Drum roll please! 25 to 30 minutes. Womp, womp, womp. And, it helps people stay asleep toward the end of the sleep cycle. And I think this underscores why one size does not fit all and prescriptions should be customized for individual needs. The last class of drugs approved for the treatment of insomnia makes a lot of sense. Ramelteon is a melatonin receptor agonist and the brand name Rosarem, get it? REM, R E M, as in rapid eye movement sleep. It's got a good mechanism of action, a good name. Problem is, it doesn't work any better than placebo. So, you can skip the potential for fatigue, nausea, and worsening of liver disease and just take a sugar pill. So, am I saying it doesn't work at all? Of course not. Why would it be approved if it didn't work? Well, it's not in Europe, but it does work to lengthen sleep time by a grand total of seven minutes. And I don't know about you, but it's going to take more than seven minutes to get rid of the bags under these eyes. So that's the gamut of drugs approved for the treatment of insomnia in the United States. But wait, there's more. Just because the FDA doesn't approve something for a particular indication, that doesn't mean that doctors can't prescribe it. And sometimes, off label prescribing is a really good thing, though it's a set up for a knock down, drag out fight with your insurance company for coverage. In addition to using the antidepressant Doxepin, many doctors prescribe other antidepressants for sleep. Things like Amitriptyline and Trazodone, even though the American Academy of Sleep Medicine advises against it because of side effects and no data showing that it works. Now, I always recommend that you consult with your health care provider regarding your medications. Always, always, always. But, I also recommend that they consult with up to date society recommendations and guidelines. That's just fair. And while they're at it, they should look at the potential adverse reactions. So, now maybe you've decided to skip the copay and just help yourself to the sleep aid aisle of the pharmacy. You could even ask the pharmacist to guide you, and I recommend that. There are two over the counter medications approved to treat insomnia. They are diphenhydramine, commonly known as Benadryl, and doxalamine, commonly known as Unisom. Side note, over the counter medications are regulated FDA, And both of these drugs are histamine blockers. Therefore, all of the fun side effects that come with that, like dry mouth, GI distress, dizziness, trouble emptying your bladder, and of course, sedation, which is the desired side effect. These medications are often combined with things like Advil or Tylenol with an added P. M. at the end, so you know what's in store for you. And here's what's in store for diphenhydramine. 8 less minutes to fall asleep and 12 more minutes of sleep. And for doxylamine, there's no data available. That's it. That's what we've got. So, maybe now you've decided just to take matters into your own hands and look for a supplement. And because you've listened to my previous podcast episode about dementia, you're gonna skip right over the Prevagen, right? Promise me. Now, in the supplement section, you're going to walk in understanding that claims, concentrations, and ingredients are not guaranteed. They're not regulated. They are, generally speaking, considered safe and ineffective. You heard that right. Safe. And ineffective. But what about melatonin? You swear it works, but does it? Maybe. It is sedating in about 10 percent of people and in everyone else, it shifts the sleep phase. So, there is a place for that such as jet lag, and I have an episode on jet lag in the show notes. But even though it may help you drift off to sleep, it probably isn't going to help you stay asleep. The half life is less than an hour, and in some people it causes stomach cramps, irritability, and even depression. It's best used in combination with other things that regulate your circadian rhythm. More to come on that. But a big one is light. And so this probably would be a great time to tell you about some exciting news I have for you. I have an upcoming series of live webinars to talk about six hidden things that keep you tossing and turning at night. And soon you'll have access to an online course called Unlock the Secret to Sleep, your personal sleep solution. I have been working so hard on this for so long that I cannot wait to share it with you. I want to help you reset your sleep and get your Z's. Now there are other supplements labeled as sleep aids and most of them again are safe and probably not effective. The exceptions on safety are kava and valerian root. Both of those have been associated with liver damage. Now it's rare, but it's very serious. Other things you might find on this aisle are chamomile, Glycine, Gryphonia, Hops, , Kava, L theanine, Lavender, , Passionflower, Nightshade, Skullcap, Strymonium, Tryptophan, , and Wild Jujube Seeds. They're all equally effective and work every bit as well as a sugar pill, but hey, sugar pills can have powerful placebo effects. And one last thing I want to mention, and that is cannabis. Bottom line is there's not enough research to say one way or another, whether it works. It does have the potential for addiction and it's not legal everywhere. So there's that. But also it's a problem that if you quit, you'll likely experience sleep disturbances that can last for several months. The bottom line is, I want you to know that you shouldn't have to choose between serious health consequences of poor sleep and the side effects and risk of sleeping pills and potions. If you suffer from insomnia, I do encourage you not to stop any medications without medical supervision and to have an honest conversation with your doctor. And if they want access to my resources, just give them my email address. I'm happy to share and they're 100 percent legit, but if good sleep eludes you, I want you to know while there's no magic pill for perfect sleep, there is a proven path to natural, restorative rest that can transform your life. Imagine waking up energized, focused, and ready to tackle your day without relying on sleeping pills or potions. Are you tired of tossing and turning at night? Desperately wishing for deep, restful sleep? I'm hosting two exclusive live webinars where I'll share my evidence based approach to achieving consistent quality sleep. Join me on March 3rd or March 5th to discover how to fall asleep naturally. and wake up refreshed, practical strategies to boost your energy and mental clarity, and solutions to common sleep challenges that keep you awake at night. Plus you'll get a chance to ask your most pressing sleep questions during a live Q& A session. So don't miss this opportunity. To revolutionize your sleep. Click the link in the show notes to save your spot now. Registration is required. And make sure you're on my email list to receive exclusive pre webinar insights and special bonuses. Your journey to better sleep starts here. Sign up right now and let's transform your nights and supercharge your days. Because good sleep is crucial for good health and healthy looks great on you. RESOURCES: FREE, live sleep masterclass registration Jet Lag Does Prevagen work? Why doctors prescribe a pill Meet Aunt Edna - Your holiday survival stress guide
A reclassificação do zolpidem pela Anvisa trouxe mudanças significativas para médicos e pacientes. José Roberto de Toledo e Talyta Vespa discutem o assunto neste episódio do UOL Prime. Com base em dados recentes e relatos de pacientes, o podcast explora os impactos dessa decisão e os desafios no controle do uso do medicamento.See omnystudio.com/listener for privacy information.
Real Life Pharmacology - Pharmacology Education for Health Care Professionals
On this episode of the Real Life Pharmacology podcast, we cover medications 101-105 of the top 200 drugs Atomoxetine is a norepinephrine reuptake inhibitor that is used in the management of attention deficit hyperactivity disorder. Zolpidem is a medication that is used for insomnia. It has a very similar adverse effect profile to benzodiazepines. Advair is a commonly used respiratory medication for asthma. It is a combination of a long-acting beta agonist and inhaled corticosteroid. Levofloxacin is a quinolone antibiotic that has a boxed warning for neuropathy, tendon rupture, and CNS adverse effects. Imipramine is a tricyclic antidepressant that is highly anticholinergic. Dry eyes, dry mouth, constipation, urinary retention, sedation, and memory impairment are potential adverse effects.
In this episode, we explore the Z Drugs—Zolpidem, Zaleplon, and Eszopiclone. Join us as we give a brief introduction to this class of medications commonly used for sleep. ANSWER TO POLL QUESTION BELOW (SPOILER) —————————————————— Answer: Choice B (Zolpidem)
Um tema alarmante que afeta diretamente a saúde pública é a venda ilegal de medicamentos controlados, especialmente o Zolpidem. Recentemente, uma operação da Polícia Civil do Distrito Federal desarticulou um esquema que envolvia a venda clandestina desse sedativo. No Brasil, o uso do Zolpidem tem crescido nos últimos anos. A Agência Nacional de Vigilância Sanitária (Anvisa) calcula que 13,6 milhões de caixas dessa medicação foram vendidas em 2018. Dois anos depois, em 2020, esse número saltou para 23,3 milhões, um crescimento de 71%. Quais são os riscos associados ao uso incorreto de Zolpidem? Como a venda ilegal afeta a saúde pública? Como esse medicamento age no organismo para induzir o sono? Giovanna Risardo e a repórter Lívia Veiga conversam com a médica neurologista e pesquisadora do Instituto do Sono, Dalva Poyares.
It's that tyme of year! AWOOOOOOO --- Support this podcast: https://podcasters.spotify.com/pod/show/luke-bellamy/support
Boa terça, angulers! Abrimos o #236 mais uma vez comentando a enchente do Rio Grande do Sul. A situação começa a caminhar para uma estabilidade preocupante. Com a água baixando e moradores voltando para suas casas, o cenário de devastação está sendo revelado. O trabalho de reconstrução está começando e o de estruturação para os desabrigados que ficarão ainda mais tempo em abrigos também. Depois, tratamos do aumento do controle sobre o Zolpidem, medicamento para insônia que virou protagonista de uma epidemia de superdosagem e uso abusivo. Sirva-se!
São mais de 70 milhões de pessoas com problema de insônia no país. Nesse cenário, cada vez mais brasileiros buscam medicamentos indutores de sono – segundo dados da Anvisa, quase 18 milhões de caixas de zolpidem foram vendidas no ano passado. Considerado por especialistas uma epidemia, o consumo do medicamento agora será mais rígido. A partir de agosto, a Anvisa estabeleceu que para comprar o zolpidem e a zopiclona será preciso ter uma receita azul. Para entender o que levou à alta exponencial no uso de indutores de sono no Brasil e quais os riscos para a saúde, Natuza Nery conversa com Dalva Poyares, neurologista especialista em sono, pesquisadora do Instituto do Sono e professora da Unifesp. Dalva explica os fatores que levaram à chamada epidemia de zolpidem, quais os riscos da automedicação e em quais casos o remédio é recomendado.
A Agência Nacional de Vigilância Sanitária (Anvisa) aprovou, recentemente, uma resolução que deixa as regras para a prescrição do Zolpidem - um medicamento indicado para o tratamento de insônia - mais rígidas. A medida foi adotada a partir do aumento de relatos de uso irregular e abusivo relacionados ao uso do remédio. O que muda com as novas normas? O Zolpidem é seguro? Como ele age no organismo? E quais os efeitos colaterais? Celso Freitas e o repórter Romeu Piccoli conversam com a neurologista e pesquisadora do Instituto do Sono, Dalva Poyares.
SUB TO THE PATREON BEFORE "BOHEMIAN GROVO (PT. II)" DROPS EXCLUSIVELY ON THE PREMIUM FEED... YOU DON'T WANT TO MISS IT! patreon.com/ParaPowerMapping Pt I of the PPM forensic examination of the K Dot v Drake beef escalation (DISScalation); Kendrick's pedo sex trafficking allegations (subliminal & explicit) against Aubrey Graham in "Euphoria", "Meet the Grahams", & "Not Like Us"; Drizzy's long history of tryna rizz up (Drizz Up lol) underage starlets in Hollywood Babylon & worldwide; the Baka Not Nice sex trafficking & assault case andevidence indicating that Baka's accuser was likely pressured or incentivized into dropping the matter & leaving the country; the Drake & Daddy Dennis Graham sexual exploitation tag team; the corporatization of the OVO traffick; Drake's sexual-impropriety-in-the-sus-music-industry pedigree via his Dad's career drumming for Jerry Lee Lewis, who married his underage adoptive cousin; the T Swift amnesia phenomenon & implications as it pertains to Drake's ability to enrapture audiences, possibly the most popular male pop artist globally; Swift's bottling of that intoxicating Beatlemania tincture; MKULTRA in the music industry; Crazy Days & Nights blind items re Drake sending his underlings to scour HS for victims; Drake & Busters (Bust-a-Nut's), aka his creepy repeat afterparties in the slightly more grown-up Chuck E. Cheese's & the 17 yr old Insta influencer sighted at one of them (not to mention followed by Dennis online); Drake & Millie Bobby Brown's text-uationship; the spine-tingling vid of Drake sniffing a teen's neck Dark Biden style & then making out w/ her after she revealed she's A-Minor onstage in CO; the Young Dabo stream where teen influencer Aya Tanjali inadvertently let slip that she either signed an NDA w/ Drake or else is suing him (likely bc he __ed her); the swirling rumours of Drake inviting HS aged girls to his parties (sourced from TikToks & even personal accounts); the Kanye connex via sus high society medical concierge service provider Dr. Farzam, who prescribed the Ozempic & Zolpidem pictured on the "MtG" cover & who was present at Pasternak's house when Ye was arrested; K Dot's lyrical barbs—"Certified lover boy? Certified Pedophiles" and the Weinstein comparison, which reminds Klonny of his sus reading of the Drake team's foreknowledge of Harvey's imminent downfall & Drake's savvy media manipulation of his decision to turn down a potential role in a Weinstein Co film, which was spun as evidence of Drake's feminism (laughable in retrospect when compared w/ the reams of evidence of grooming & likely sex blackmail we're compiling); the symbolic symmetries b/w Drake's OVO label imprint & Bohemian Grove, the hedonistic secret society up in the Redwoods in Cali that has counted some of the wealthiest & most powerful capitalist & political elite among its number; the "Atlanta" Drake party ep, which is highly interesting when reexamined in light of the cresting divulgences of Drake misbehavior; a comparison of the bussing in of models to "True Detective" Season 2 and the Bohemian Grove/ Eyes Wide Shut-esque sex lodge; the "Euphoria" connection, which will take us to Israel, I O F's Intel Corps, and potentially into the v heart of the M o s s a d i s t Epstein network itself; the shooting of Drake's security guard outside "The Embassy" recently; Rob Ford; a ticker tape of NDAs; the parapolitical research & multimedia aspects of Kendrick Lamar's "Meet the Grahams" cover; Klonny's contention the Maybach gloves are a double entendre evoking OJ Simpson (and possibly setting the stage for subliminals hinting at Drake's hand in XXXTentacion's death, for which Rap Game presents a compelling case)... Full notes on the Patreon. Huge thanks to Rap Game Edward Bernays for joining for this mammoth deep dive. Make sure to give him a follow on Twitter at @Edward__Bernays ... Tracks: | Metro Boomin - "BBL Drizzy" | | Kendrick Lamar - "Meet the Grahams" | | Kendrick Lamar - "Not Like Us" |
Atenção (disclaimer): Os dados aqui apresentados representam minha opinião pessoal. Não são de forma alguma indicações de compra ou venda de ativos no mercado financeiro. Abril exportações mensais de carne bovina do país https://www.noticiasagricolas.com.br/noticias/boi/376227-abril-tem-o-maior-volume-historico-nas-exportacoes-mensais-de-carne-bovina-do-pais.html Selic BC https://www.poder360.com.br/economia/saiba-como-votou-sobre-a-selic-cada-um-dos-diretores-do-bc/ fim da isenção de importações abaixo de US$ 50 https://www.cnnbrasil.com.br/politica/relator-inclui-jabuti-em-programa-automotivo-e-preve-fim-da-isencao-de-importacoes-abaixo-de-us-50/ Inflação 3,69% https://www.poder360.com.br/economia/inflacao-mensal-acelera-mas-taxa-anualizada-cai-para-369/ Suzano US$ 15 bi pela International Paper https://braziljournal.com/suzano-faz-oferta-de-us-15-bi-pela-international-paper-diz-reuters/ Mills compra JM empilhadeiras https://braziljournal.com/mills-compra-jm-e-estreia-no-segmento-de-empilhadeiras/ Bradesco e Rede D'Or https://istoedinheiro.com.br/bradesco-e-rede-dor-sao-luiz-se-unem-para-criar-nova-rede-de-hospitais/ Parceira da Shein no Brasil entra em recuperação judicial https://exame.com/invest/mercados/parceira-da-shein-no-brasil-entra-em-recuperacao-judicial/ Multi (MLAS3) fabricará aparelhos da chinesa OPPO https://www.moneytimes.com.br/nova-marca-de-celular-multi-mlas3-fabricara-aparelhos-da-chinesa-oppo-veja-fotos-do-que-pode-vir-ao-brasil/ Bloomin' Brands avaliando venda do Outback no Brasil https://valor.globo.com/empresas/noticia/2024/05/07/bloomin-brands-dona-do-outback-avalia-venda-de-operaes-no-brasil.ghtml Sua Política com Felipe Frazão 09.05.24 https://podcasts.apple.com/br/podcast/sua-pol%C3%ADtica-com-felipe-fraz%C3%A3o-09-05-24/id1226660489?i=1000655048912 É falsa a informação de que doações são barradas no RS: 'Pessoas têm que doar sem medo' https://podcasts.apple.com/br/podcast/%C3%A9-falsa-a-informa%C3%A7%C3%A3o-de-que-doa%C3%A7%C3%B5es-s%C3%A3o-barradas-no/id1588271061?i=1000654990138 Decisão do STF sobre lei das estatais 'é completamente absurda' https://podcasts.apple.com/br/podcast/decis%C3%A3o-do-stf-sobre-lei-das-estatais-%C3%A9-completamente/id203963267?i=1000655191059 Lei das Estatais: 'em decisão sem pé nem cabeça, STF contraria espírito da própria lei' https://podcasts.apple.com/br/podcast/lei-das-estatais-em-decis%C3%A3o-sem-p%C3%A9-nem-cabe%C3%A7a-stf-contraria/id203963267?i=1000655199291 Conheça que são os 'Silverinhas'. Grupo é novo foco de treta na Petrobras https://podcasts.apple.com/br/podcast/conhe%C3%A7a-que-s%C3%A3o-os-silverinhas-grupo-%C3%A9-novo-foco-de/id203963267?i=1000654810875 Almirante Negro: o debate sobre o heroísmo de João Cândido https://podcasts.apple.com/br/podcast/almirante-negro-o-debate-sobre-o-hero%C3%ADsmo-de-jo%C3%A3o-c%C3%A2ndido/id1477406521?i=1000654625567 UOL Prime #14: O vício em Zolpidem, a droga do sono https://podcasts.apple.com/br/podcast/uol-prime-14-o-v%C3%ADcio-em-zolpidem-a-droga-do-sono/id1574996957?i=1000652826032 The Intelligence: Our meeting with Macron https://podcasts.apple.com/br/podcast/the-intelligence-our-meeting-with-macron/id151230264?i=1000654425046 One Strongman, One Billion Voters, and the Future of India https://podcasts.apple.com/br/podcast/one-strongman-one-billion-voters-and-the-future-of-india/id1200361736?i=1000655036779 The Balkan gangsters who became Europe's top cocaine suppliers https://podcasts.apple.com/br/podcast/the-balkan-gangsters-who-became-europes-top-cocaine/id1665219519?i=1000654553011 Bird Flu—It's in Milk? https://podcasts.apple.com/br/podcast/bird-flu-its-in-milk/id1302281912?i=1000654399765 The First Pig to Human Kidney Transplant https://podcasts.apple.com/br/podcast/the-first-pig-to-human-kidney-transplant/id1602541473?i=1000653492137 Drone That Delivers https://podcasts.apple.com/br/podcast/designing-a-drone-that-delivers/id1602541473?i=1000652792345
José Roberto de Toledo conversa com a repórter Talyta Vespa sobre o vício em zolpidem, hipnótico para dormir, que atormenta médicos pelo Brasil. Alguns especialistas já chamam de epidemia o consumo exacerbado do hipnótico. See omnystudio.com/listener for privacy information.
Olá, eu sou Leo Lopes e este é o POD NOTÍCIAS, a sua dose semanal de informação sobre o mercado de podcasts no Brasil e no mundo! Hoje é segunda-feira, dia 18 de março de 2024 e esta é a nossa sétima edição! 1 - Na última semana, foi divulgado pelas empresas Rephonic e PodMatch o último AE Report, um relatório mensal sobre podcasts de entrevista. Os dados desse mês de março apontam que os podcasts de entrevista não estão tendo um crescimento expressivo, mas por outro lado, estão com números estáveis. Além disso, segundo a definição da pesquisa, só 13% de todos os podcasts desse tipo, são considerados podcasts "ativos e estabelecidos". Aqui vale a gente definir certinho o que é um podcast ativo e estabelecido segundo eles: é um podcast baseado em entrevistas com pelo menos 100 episódios publicados, cujo último episódio tenha sido postado a 10 dias ou menos, e que seja apresentado por alguém que não é uma celebridade - e nem parte de uma grande rede de mídia. Isso significa que, embora o número total de podcasts tenha aumentado em cerca de 20 mil entre fevereiro e março de 2024, o aumento de podcasts ativos foi de apenas 13 mil - já que vários podcasts deixaram de ser ativos nesse meio-tempo. Outro dado que o relatório apontou, foi que apenas 3,7% dos podcasters conseguem produzir mais de 300 episódios. A grande maioria dos programas acaba sendo encerrado depois do primeiro episódio. Link 2 - Um outro relatório que saiu recentemente, foi o Podcast Ranker da Triton Digital, com os números de fevereiro de 2024. A Triton avalia várias categorias do ecossistema do áudio mundial, e uma das mais importantes é a da Rede Que Mais Gerou Lucro com Áudio. O primeiro lugar do último mês ficou com a SiriusXM, que sempre tá ali, flutuando entre o primeiro e o terceiro lugar. A segunda empresa do pódio foi a NPR, que veio seguida de perto pela Wondery. A pesquisa também deu destaque para os podcasts que lideram em downloads e número de ouvintes. Nos Estados Unidos, os maiores destaques foram os programas News Now da NPR e o Crime Junkie, enquanto aqui na América latina, alguns dos programas mais baixados e ouvidos foram O Assunto do G1 (brasileiro), o Panda Show Sin Censura (mexicano) e o Modus Operandi (brasileiro). Todo mês, o relatório Ranker coloca uma grande ênfase na importância que os dados têm para profissionais de marketing e criadores de conteúdo, e o exemplo prático dessa vez, foi o caso do podcast que foi deletado pelo Spotify. Link 3 - E que caso é esse? Bom, pra quem não está sabendo, uns 10 dias atrás o podcast "Evolving Prisons" da podcaster Kaigan Carrie foi removido do Spotify, depois que a empresa alegou que estavam acontecendo atividades suspeitas relacionadas à pagamentos na plataforma. E, como o feed RSS também desapareceu, o programam começou a ser removido de outras plataformas e diretórios. No entanto, a remoção do podcast foi um engano. O programa foi deletado do Spotify menos de 48 horas depois de ser indicado na categoria "Podcast Independente Excepcional" na premiação True Crime Awards. O Spotify fez uma revisão no dia seguinte do erro, mas aí a Kaigan já tinha perdido seguidores, assinantes pagos, estatísticas e toda a receita acumulada dos últimos 4 meses. Depois da cagada, o Spotify declarou que estava trabalhando pra reverter a situação. E embora eles tenham conseguido restaurar as estatísticas e reembolsar a renda perdida, a podcaster sofreu um grande prejuízo, principalmente pela perda de seguidores em outras plataformas. E o Spotify pode ter mandado e-mail pra todos os inscritos do Evolving Prisions, pedindo pra eles refazerem a assinatura, mas quantos deles vão mesmo fazer isso? 50%? 80%? Todos? Enfim. A Kaigan disse que perdeu completamente a confiança no Spotify e que vai buscar outro serviço de hospedagem pro seu podcast, com toda razão. Link AINDA EM NOTÍCIAS DA SEMANA: 4 - Com o fim iminente do Google Podcasts, o YouTube Music continua aumentando o seu catálogo de novos recursos, e a adição dessa vez é do "Trim Silence", que elimina pausas em podcasts. O recurso não existia no YouTube Music antes da versão v6.43 já que o aplicativo foi feito pra ouvir música, mas como ele têm se adaptado às demandas dos ouvintes de podcast, o novo "aparador de vácuos" identifica e pula períodos de silêncio nos episódios de podcast, o que reduz o tempo total da reprodução do áudio. Por enquanto, a funcionalidade não tá disponível pra todos os usuários do YouTube Music, provavelmente porque os desenvolvedores estão esperando uma atualização adicional do servidor ou do próprio aplicativo. Vamos esperar. Link 5 - A revista online The Baptist Paper está incentivando os fiéis da Igreja Batista a criarem podcasts, destacando vários benefícios da nossa mídia. Segundo um informativo publicado pelo portal na semana passada, um podcast pode ser uma adição valiosa para as igrejas, porque oferece uma forma conveniente e íntima de comunicação com os fiéis. Além de se encaixarem na rotina diária dos ouvintes, os podcasts também permitem uma conexão pessoal genuína, inspiram os ouvintes, e se tornam uma ferramenta poderosa pra promover o crescimento espiritual. Outra vantagem que o Baptist Paper destacou, foi a facilidade de compartilhamento dos podcasts, o que (em tese) ajudaria a ampliar o alcance da instituição. É importante a gente ressaltar aqui que os podcasts religiosos são muito populares no Brasil. Nas paradas do Spotify, por exemplo, os podcasts "Café Com Deus Pai" e "Frei Gilson Podcast" estão sempre - SEMPRE! - incluídos no TOP 10 dos mais ouvidos. É interessante ver como o podcasting têm sido valorizado em todo tipo de comunidade. Link E MAIS: 6 - Uma podcaster independente ganhou um processo judicial de marca registrada contra outra criadora de conteúdo que estava usando o mesmo nome do seu podcast. O caso aconteceu na Australia. Canna Campbell, uma influencer de finanças que também é conhecida como SugarMamma, foi considerada culpada por violação de direitos autorais na última segunda-feira, dia 11 de março. Ela passou meses usando o termo "Financial Foreplay" em seu podcast, só que a marca Financial Foreplay® já estava registrada desde 2016 para a proprietária Rhondalynn Korolak, outra podcaster bem menos conhecida que a Canna. Segundo os autos do processo, a Canna Campbell tentou registrar o seu podcast com esse nome sem sucesso, porque afinal de contas ele já estava registrado pra Rhondalynn, mas mesmo com o pedido de reconhecimento negado, ela continuou usando o nome em iniciativas comerciais, palestras pagas e acordos publicitários com lucro ativo. A Rhondalynn afirmou que a Canna Campbell usou sua propriedade intelectual sem autorização, e criticou suas justificativas no tribunal. Com o desfecho, a influencer foi obrigada a pagar cerca de 75 mil dólares em custos legais depois de infringir a marca registrada. E agora são dois trabalhos: o de pagar o pato e de refazer toda a identidade do podcast. Podia ter sido evitado se ela tivesse sido honesta desde o começo. Link 7 - A Prefeitura de São Paulo inaugurou o terceiro estúdio público de podcast da cidade, chamado Sampa Cast. A iniciativa foi realizada em parceria com a Secretaria Municipal de Desenvolvimento Econômico e Trabalho e a Agência São Paulo de Desenvolvimento, no intuito de fortalecer a criação de conteúdo e incentivar o empreendedorismo na área da comunicação e do audiovisual. Mais de 700 pessoas já utilizaram os serviços dos estúdios públicos, o que se reflete em mais de 1.200 horas de conteúdo gravado. Um exemplo deles, é o "Compartilha Cast", criado pela Vivian Castanheda e a Priscila Berquó, que já gravaram mais de 90 episódios. Os estúdios estão localizados em Pinheiros, Heliópolis e Lapa, e operam de segunda a sexta-feira, das 9h15 às 17h30, com agendamento realizado todo mês, através do site da Ade Sampa. O link, como sempre, vai estar na descrição desse episódio. Link 8 - E pra quem é fã de podcast e de séries animadas, eu tenho uma boa notícia: a empresa Starburns Industries, que produziu Rick & Morty, vai adaptar o podcast de comédia "Hello From The Magic Tavern" pra uma série animada. A adaptação vai ser feita em parceria com a Play Hooky Productions, comandada pelo ator Sam Rockwell e o executivo Mark Berger. O podcast Hello from the Magic Tavern é um programa de storytelling, que segue os anfitriões enquanto eles entrevistam criaturas, magos e aventureiros na terra fantástica de "Foon". O apresentador principal do podcast é Arnie Niekamp, que criou o programa com uma mistura de narrativa, comédia improvisada e show do absurdo. Quem acompanha ele nessa jornada são seus co-apresentadores Chunt, o metamorfo, e Usidore, o mago. Essa não é a primeira vez que um podcast é transformado em animação, o exemplo mais famoso que a gente tem até agora é o The Midnight Gospel, que foi feito em cima do podcast The Duncan Trussell Family Hour, e ta aí pra não me deixar mentir. Até o momento, todos os envolvidos no projeto disseram que estão muito animados com a adaptação. Os criadores do podcast estão postando nas suas redes sociais que não vêem a hora de compartilhar sua visão com os fãs, e de contar as suas histórias em um novo formato. Link HOJE NO GIRO SOBRE PESSOAS QUE FAZEM A MÍDIA: 9 - Depois de um hiato que foi anunciado como "o fim do podcast", o Foro de Teresina da revista piauí retornou nesta última sexta-feira, dia 15, com uma nova bancada. O Foro de Teresina tinha sido interrompido no final de outubro do ano passado, depois das saídas de Thais Bilenky e José Roberto de Toledo, que foram recebidas com revolta por parte do público. Na época, a revista decidiu encerrar o podcast, que estava em produção tinha cinco anos e meio. Agora, de volta ao setor, o programa é composto pelo jornalista Fernando de Barros e Silva, pela jornalista Ana Clara Costa e pelo cientista político Celso Rocha de Barros - que já tinha participado algumas vezes como convidado na estrutura antiga do podcast. Ele é, também, autor do livro "PT, uma história" e colunista da Folha de S.Paulo. Ana Clara Costa tem experiência na Veja, nO Globo e Revista Época. Além das mudanças na bancada, o podcast também teve alterações na trilha sonora e na identidade visual. A produção continua nas mãos da Rádio Novelo, com direção de Mari Faria e coordenação geral de Évelin Argenta. Link 10 - E na nossa Caixa de perguntas do Instagram na semana passada, a gente perguntou pra você, o nosso ouvinte, qual foi o último podcast que realmente te surpreendeu ou prendeu a sua atenção. Essa foi mais uma daquelas perguntas que trouxe várias respostas bem variadas, entre elas: o Pausa Pra Sentir do Thiago Queiroz, o 80 WATTS do Shi, o Dois Empregos do Caio e do Klaus, o Dentro da Minha Cabeça do Príncipe Vidane e, pra minha alegria, até o Acepipes e Birinaites foi mencionado. Vários outros programas também foram citados, mas por conta de um bug do Instagram que sumiu com o nosso story da caixinha, a gente perdeu umas 10 respostas dos ouvintes. Valeu pela eficiência, viu, Instagram? Só que não. Agora, deixando os perrengues de lado, nessa semana a gente quer saber outra coisa: há quanto tempo você ouve podcasts? A caixinha de perguntas vai ficar aberta nos stories do Instagram do Pod Notícias por 24 horas - se o Instagram não der outro bug -, então não deixe de acessar lá ainda hoje pra deixar a sua contribuição, e também não deixa de seguir a gente em @pod.noticias. Instagram do Pod Notícias SOBRE LANÇAMENTOS: 11 - Na segunda-feira passada foi lançado o podcast Sambas Contados, apresentado por ninguém mais, ninguém menos do que o cantor e compositor Emicida. O programa é uma parceria entre a Globo e o Laboratório Fantasma, e mergulha fundo na história do samba em uma série de 10 episódios lançados de segunda a sexta-feira, ao longo de duas semanas. No podcast, o Emicida não só explora a evolução do gênero musical, mas também reverencia os grandes nomes do samba, ao mesmo tempo que fala sobre a importância histórica e cultural do samba na sociedade brasileira. Todos os episódios lançados até agora tem um conteúdo muito bacana, que vale muito a pena ouvir, e que celebra uma parte muito importante da música brasileira. Os episódios tem entre 20-30 minutos, e o programa já está disponível em todas as principais plataformas de áudio. Link 12 - Também foi lançado na última semana o novo podcast da BBC Sounds, o "Miss Me?", apresentado por duas amigas bastante famosas: a cantora Lily Allen e a apresentadora de televisão Miquita Oliver. No primeiro episódio, a dupla falou sobre as diferenças entre cerimônias de premiação no Reino Unido e nos Estados Unidos, desavenças familiares, páginas da Wikipédia e até aquela foto da Kate Middleton que deixou a internet fervendo em teorias da conspiração na semana passada. O podcast está programado pra ir ao ar duas vezes por semana; nas segundas-feiras elas vão abrir participação da audiência sobre algum tema específico, e na quinta-feira elas vão só conversar sem filtro - daquele jeito que amigos de longa data fazem. Os ouvintes podem enviar as suas participações por e-mail. O Miss Me é publicado pela network da BBC, mas já está disponível em todas as principais plataformas de podcast - em inglês, que é o idioma das apresentadoras. Link RECOMENDAÇÃO NACIONAL: 13 - E nessa semana, nossa recomendação nacional vai pro fantástico podcast Rádio Escafandro, apresentado pelo jornalista Tomás Chiaverini. O programa segue a linha de documentário, e em cada episódio faz uma investigação jornalística profunda sobre algum tema variado. Lá no Escafandro já foi falado sobre greenwashing, o vício que população brasileira desenvolveu em Zolpidem, a monogamia, uso de psicodélicos e muito mais. Tudo isso abordado com seriedade e irreverência - ao mesmo tempo. Os episódios tem mais ou menos 1 hora de duração, e são montados com entrevistas inéditas, gravações em campo e áudios de arquivo, além de, é claro, a narração do Tomás costurando tudo. O Rádio Escafandro vai ao ar quinzenalmente, às quartas-feiras, e está disponível em todas as principais plataformas de áudio. Então você já pode assinar o programa no seu agregador de podcast preferido e acompanhar de perto esses mergulhos profundos que buscam a verdade e os fatos. Link E assim a gente fecha esta sétima edição do Pod Notícias. Acesse podnoticias.com.br para ter acesso à transcrição e os links das fontes de todas as notícias deste episódio! Acompanhe o Pod Notícias diariamente:- Page do Linkedin- Instagram- Canal público do Telegram Ouça o Pod Notícias nos principais agregadores:- Spotify- Apple Podcasts- Deezer- Amazon Music- PocketCasts O Pod Notícias é uma produção original da Rádiofobia Podcast e Multimídia e publicado pela Rádiofobia Podcast Network, e conta com as colaborações de:- Camila Nogueira - arte- Eduardo Sierra - edição- Lana Távora - pesquisa, pauta e redação final- Leo Lopes - direção geral e apresentação- Thiago Miro - pesquisa Publicidade:Entre em contato e saiba como anunciar sua marca, produto ou serviço no Pod Notícias.See omnystudio.com/listener for privacy information.
Publicado orginalmente em 1 de dezembro de 2021. O hemitartarato de zolpidem está na classe dos medicamentos hipnóticos. Se a gente quiser ser mais preciso, ele é um agonista do receptor Gaba. No Brasil, também é conhecido pelo nome comercial de Stilnox. Nos Estados Unidos, Ambien. O zolpidem age direto nas sinapses do cérebro humano. Tem e incrível capacidade de ir lá no interruptor inexistente da nossa cachola e clic. Desligar. Ou seja, é basicamente um sonífero. Um sonífero que, apesar de extremamente eficaz contra insônia, traz uma série de riscos à saúde, especialmente se for usado de forma abusiva ou inadequada. O que tem acontecido bastante, uma vez que seu uso virou modinha entre jovens que costumam postar suas desventuras com o remédio nas redes sociais. – Colabore com a Rádio Escafandro e receba recompensas. Clique aqui. ***** Episódio relacionado #37 – O sonho do Sidarta Mergulhe mais fundo Capitalismo tardio e os fins do sono (link para compra) Entrevistados do episódio Gabi Criadora da conta @zolpidembot Rosa Hasan Médica neurologista, responsável pelo laboratório de sono e pelo ambulatório de sono do Instituto de Psiquiatria do HCFMUSP. Responsável pelo ambulatório do sono e pelo laboratório do sono da Faculdade de Medicina do ABC Ficha técnica Concepção, produção, roteiro, apresentação, sonorização e edição: Tomás Chiaverini Trilha sonora tema: Paulo Gama Mixagem: Vitor Coroa Design das capas: Cláudia Furnari
In this podcast, Dr. Schenck discusses zolpidem-induced sleeping disorder and eating disorder. Listen and find out important tips and considerations, such as this being more common in females, alerting bed partners, being careful with zolpidem doses over 10 mg, and more. Faculty: Carlos Schenck, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.5 CME: Parasomnias Triggered by Sedative-Hypnotics: Sleepwalking and Sleep-Related Eating Disorder Zolpidem-Induced Sleepwalking and SRED
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Temporada 2 e Episódio 4, e nele você vai ouvir sobre o sono. Insônia, sonambulismo, Zolpidem, melatonina, paralisia do sono, lendas urbanas, uso de telas, o que funciona e o que não funciona e impactos a nossa saúde, além de algumas curiosidades. Já se perguntou se dá pra recuperar o sono perdido ou por que bocejamos ao ver outras pessoas ou até animais bocejarem, ou até quando lemos sobre o bocejo? Pois é, o sono perdido a gente responde por lá, já o bocejo por contágio, ou seja, aquele que imitamos ao ver outro fazendo é uma forma comum do que chamamos de comportamento echophenomena, ou seja, a imitação involuntária de palavras e ações de um terceiro, e isso está diretamente ligado a excitabilidade do córtex motor primário. Em resumo, quanto maior a excitabilidade dessa parte do cérebro, maior nossa vontade de bocejar :) Bora com a gente descobrir um pouco mais, e aprender mais um tanto sobre neurociência :) Aproveita pra se inscrever aqui e deixar aquela constelação de estrelas para o podcast =]
Episode 148: Leg CrampsFuture Dr. Weller explains the pathophysiology, management, and prevention of leg cramps. Hector Arreaza adds comments and anecdotes about leg cramps. Written by Olivia Weller, MS4, American University of the Caribbean School of Medicine. Comments by Hector Arreaza, MD.You are listening to Rio Bravo qWeek Podcast, your weekly dose of knowledge brought to you by the Rio Bravo Family Medicine Residency Program from Bakersfield, California, a UCLA-affiliated program sponsored by Clinica Sierra Vista, Let Us Be Your Healthcare Home. This podcast was created for educational purposes only. Visit your primary care provider for additional medical advice.Definition: Known also as “Charlie horses,” leg cramps are defined as recurrent, painful, involuntary muscle contractions. They can last anywhere from seconds to several minutes, with an average of nine minutes per episode. They are usually nocturnal and thus may be associated with secondary insomnia. Location: A muscle cramp can happen in any muscle in the body, but they occur most commonly in the posterior calf muscles, but they can also involve the thighs or feet. They are more common in women than men and the risk increases with age.Although they are experienced by 7% of children and up to 60% of adults, the exact mechanism remains unknown and there is no definitive treatment at this time. PathophysiologyThere is one leading hypothesis for nocturnal cramps that occur in the posterior calf muscles, and it is related to your sleeping position. When you are laying down in bed your toes are pointed which causes passive plantar flexion while the muscle fibers are shortened maximally. This causes uninhibited nerve stimulation with high-frequency involuntary discharge from lower motor neurons, which causes cramping. Another possible etiology is nerve damage because neurologic conditions such as Parkinson's disease are associated with a higher-than-normal incidence of cramps. Peripheral neuropathy, or damage to the connection between motor nerves and the brain can lead to hyperactive nerves when they are not being properly regulated. Thus, diabetes mellitus is a major risk factor for nocturnal cramps due to the high blood sugar levels damaging the small blood vessels which supply the muscles. Decreased blood flow has also been attributed as a cause of leg cramps. People with diseases that affect their vasculature, such as varicose veins or peripheral arterial disease also have a higher incidence of leg cramps. Decreased blood flow to the muscles means less delivery of oxygen and nutrients to the muscles which makes them more susceptible to fatigue. Muscle overuse is one of the dominant explanations for cramping. This can be related to doing too much high-intensity exercise without adequate stretching before and after. Pregnant women have added weight which puts extra strain on the muscles, along with sitting or standing for long periods of time, poor posture and flat feet. Notably, when we age, our tendons naturally shorten and they cannot work as hard, or as quickly which makes them more susceptible to overuse. Additionally, there are mineral deficiencies such as magnesium and potassium or decreased levels of B and D vitamins. With this in mind, people with renal failure that are on hemodialysis have an increased risk of nocturnal leg cramps. And finally, we have medications, some of which are related to mineral deficiencies. The main contributors are statins, diuretics, conjugated estrogens, gabapentin or pregabalin, Zolpidem, clonazepam, albuterol, fluoxetine, sertraline, raloxifene, and teriparatide (analog for parathyroid hormone). Management and preventionThere is no magic treatment to make them go away immediately, however, there are different remedies you can try to help facilitate. My Grandma told me about an old wives' tale, that if you put a bar of soap in your bed at your feet while you sleep, you won't get cramps at night. Maybe it works by the placebo effect, maybe there's a mechanism going on there I don't understand who knows, I'll have to do a study on it. If you get them very often, you can keep a foam roller or a heating pad next to your bed in preparation for when they come. Stretching the muscle is known to be very effective, as well as applying heat or ice to the affected area. You can also try massaging the muscle with your hands or getting out of bed to stand or walk around. Elevating the leg while laying down in bed can also be beneficial. In terms of prevention, you can try out different sleeping positions to see if one works better for you. If you usually sleep on your back, you can stick a pillow under your feet to help keep your toes pointed upward. Or, if you sleep on your stomach you can try to keep your feet hanging off the bed. Another tip is loosening the sheets or blankets around your feet. Daily stretching, especially before and after exercise as well as before bed is useful. Make sure to exercise, stay hydrated, and limit your alcohol and caffeine consumption. You also want to wear supportive shoes or use orthotic inserts in your shoes, especially if you spend lots of time on your feet during the day. Medications/supplements: Since various deficiencies can cause cramps, one way to prevent them is to take supplements such as magnesium, vitamin D, and B12 complex. And as a last resort, you can try medications. Calcium channel blockers such as diltiazem or verapamil have been used, and muscle relaxants including Orphenadrine (Norflex®) and Carisoprodol (Soma®). Gabapentin is an anticonvulsant commonly used as a neuropathic pain medication; this used to be used to treat leg cramps but later it was found that they can actually increase the frequency of muscle cramps so they are no longer used. Quinine was also used for many years to treat leg cramps; however, it is no longer recommended because of drug interactions and serious hematologic effects such as immune thrombocytopenic purpura (ITP) and hemolytic uremic syndrome (HUS). Summary: Leg cramps are common, the pathophysiology is unclear, but may be related to problems with blood flow, the nervous system, sleeping position, and muscle overuse. Treatment includes nonpharmacologic therapies such as changes in sleeping position, heat, and massaging; and medications/supplements that may be useful include Carisoprodol (Soma®), diltiazem, gabapentin (Neurontin), magnesium, orphenadrine (Norflex®), verapamil, and vitamin B12 complex.____________________________Conclusion: Now we conclude episode number 148, “Leg Cramps.” Future Dr. Weller explained that the etiology of leg cramps is multifactorial. Some theories about why leg cramps happen include poor circulation, muscle overuse, dysfunctions in the nervous and musculoskeletal systems, electrolyte imbalances, mineral deficiencies, and more. Some therapies were discussed, including changes in position while sleeping, massage, heat pads, and medications such as calcium channel blockers, muscle relaxants, and supplements of magnesium and Vitamin B12. Gabapentin is a medication that can cause leg cramps, but some sources recommend it as a treatment as well. This week we thank Hector Arreaza and Olivia Weller. Audio editing by Adrianne Silva.Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week! _____________________References:Leg Cramps. Cleveland Clinic. (2023, May 6). https://my.clevelandclinic.org/health/diseases/14170-leg-crampsAllen, R. E., & Kirby, K. A. (2012, August 15). Nocturnal leg cramps. American Family Physician. https://www.aafp.org/pubs/afp/issues/2012/0815/p350.htmlMayo Foundation for Medical Education and Research. (2023, March 2). Night leg cramps. Mayo Clinic. https://www.mayoclinic.org/symptoms/night-leg-cramps/basics/definition/sym-20050813Royalty-free music used for this episode: Simon Pettersson - Good Vibes_Sky's The Limit_Main. Downloaded on July 29, 2023, from https://www.videvo.net/
Hören statt lesen: Chefredakteurin Julia Pflegel hat den Artikel zum Wirkstoff Zolpidem aus unserer Serie Fresh-up vertont. Zolpidem ist ein verschreibungspflichtiges Hypnotikum und gehört zu den Z-Substanzen. Hören Sie gleich mal rein! (06:46 Min) https://www.das-pta-magazin.de/service-und-mehr/heftarchiv/artikel/serie-fresh-up-zolpidem-3315181.html
O PODCAST do MHM de hoje é com Amanda Ramalho. Vamos falar sobre a saúde mental dos brasileiros. Por que somos o país mais ansioso do mundo? Por que homens sofrem tanto de problemas como ansiedade e depressão? Edson Castro e Amanda Ramalho conversam sobre saúde mental e suas complicações. Confira. Veja tudo que falamos sobre SAÚDE MENTAL com Amanda Ramalho: 00:00 - Introdução 01:48 - Saúde mental no Brasil 08:09 - Saúde mental é acessível? 15:50 - Homens e saúde mental 22:18 - Fim de relacionamento 29:39 - Diagnóstico de Autismo em adultos 43:38 - Vício em Zolpidem 01:09:07 - Como lidar com pessoas com problemas de saúde mental 01:20:46 - Importância do Setembro amarelo 01:26:53 - Saúde mental e mercado de trabalho
Deputy District Attorneys Teresa Pham and Jorge Del Portillo talk about their trial strategies in prosecuting People v. Jade Janks.On December 21, 2022, Jade Janks was found guilty of first degree murder. Janks murdered her former stepfather, Tom Merriman, after discovering nude photographs of herself on Tom's computer. Tom was the founder of the Butterfly Farms in Encinitas, CA and the murder took place in Solana Beach, CA.This case received lots of publicity and was featured on CourtTV. FACTS:On December 23, 2020, Tom was transferred from Scripps Hospital to an aftercare facility and Jade Janks decided to clean Tom's apartment for him before he was discharged. While she was cleaning Tom's apartment, she discovered nude photos of herself on his computer. She was so disturbed by the discovery that she couldn't shower alone and feared Tom would be discharged early and come home.She began plotting the murder and sought help from a “fixer”, Alan Roach, who was a friend of a friend. The plan was to dose Tom with sleeping pills, get him to his bed, suffocate him, and stage it to look like an overdose. On December 31, 2020, Janks dosed Tom after picking him up from Aviara Healthcare, but the fixer never showed up. The fixer sent his buddy Brian Salomon to help out, but when she asked Brian to strangle Tom, Brian immediately left. Janks called her friend Adam for help. When Adam showed up, she confessed to dosing , suffocating and strangling Tom to death. She asked Adam to move Tom's body into a wheelbarrow and into Tom's bed to make it look like an overdose. Adam didn't want any part of it and left.Adam reported to the police that his friend confessed to murdering Tom. When authorities were looking for Tom, they couldn't find him. When they brought Janks in for questioning, she claimed not to know where he was.After hours of searching inside the property, in the early morning hours of Jan 2, 2021, detectives found Tom's body buried under a pile of trash. After arresting Janks and searching her cell phone, detectives found very suspicious text messages including:I just dosed the hell out of him.I really didn't want to involve that many people.It's going to be Weekend at Bernie's.I can't keep a kicking body in my truck. (*says truck but likely meant trunk)An autopsy found no signs of strangulation but did find toxic levels of zolpidem, otherwise known as Ambien.Crime or Fiction: Each episode we look at the laws on the books and quiz the panelists to see if they can guess which law is fake. 2 are real, 1 is fake--can you guess which one is the fake? The theme of this episode are laws from the Solana Beach Municipal Code.A. It's illegal to have an apiary in a residential zone.B. It's illegal to tattoo a person's skin if it has a rash or pimples.C. It's illegal to have bamboo over 15 feet tall. Disclaimer: The views expressed on this podcast are solely of the speakers and do not reflect the views of the Deputy DA's Association nor the District Attorney.Questions and comments can be emailed to crimenewsinsider@gmail.com.Featured in the Top 10 San Diego Podcasts!Featured in the Top 10 Criminal Law Podcasts!Website: https://sdddaa.net/Facebook: https://www.facebook.com/SanDiegoDDAs/Twitter: @CrimeNewsInsidr, @SanDiegoDDAsInstagram: @sandiegoddasMusic by: The Only Ocean - "Snake"Image by: Pixabay user Michael Gaida.
Desde sempre, na cultura ocidental, experimentar álcool e beber em excesso eram considerados marcadores da juventude, mas com a Geração Z isso tem mudado. Não é difícil encontrar pesquisas e matérias que mostram que a Geração Z bebe menos, o que pode até dar uma ideia de que eles são mais cuidadosos e "controlados" que as outras gerações, mas não é bem assim.Você com certeza se deparou com os inúmeros relatos de pessoas que tiveram episódios de viagens e delírios com o famigerado Zolpidem e isso não é novo para eles. Enquanto as porcentagens sobre o consumo de álcool diminuem, outro fenômeno vem ganhando força: o consumo de medicamentos.Estamos falando de uma nova relação com essa realidade da saúde mental, que já é comum no vocabulário desses jovens, e é baseada fortemente na visão pragmática que eles têm da vida.Nesse CAOScast Fármaco Recreação, vamos te contar como os jovens latinos têm usado medicamentos pelos efeitos colaterais, e não apesar deles, para hackear o próprio corpo e quais as causas disso.JOGA NA RODAMarina Roale: Meu Ano de Descanso e Relaxamento, de Ottessa MoshfeghCarmela Moraes: Take Your Pills, NetflixWesley Xavier: Maniac, NetflixMichel Alcoforado: Como Mudar Sua Mente, de Michael PollanO CAOScast é uma produção exclusiva do Grupo Consumoteca.Esse episódio teve pesquisa feita pelo nosso time de consumer insights com coordenação da Head de Pesquisa Marina Roale e Carmela MoraesRoteiro e Produção: Vanessa VieiraEdição: Wesley XavierIdentidade Visual: Juliana SilvaNos siga nas redes sociais:@grupoconsumoteca e @michelalcoforadoEntre no nosso grupo no Telegram: https://t.me/+59EBuLah2slhNGMx
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Zolpidem: vendas do remédio para insônia explodem no Brasil, causando aumento de casos de alucinações e dependência. Indicado para quem tem dificuldade para dormir, medicamento "desliga" o cérebro do paciente e o uso inadequado pode provocar efeitos colaterais gravíssimos, alertam especialistas. Em entrevista à CBN Vitória, a neurologista Dalva Poyares, pesquisadora do Instituto do Sono, fala sobre o assunto.
Relatos têm se repetido nas redes sociais: são pessoas contando histórias de alucinação em tom cômico após terem tomado um remédio prescrito para o tratamento de insônia: o Zolpidem.
My guest this week, Morgan Adams is a double certified sleep coach. Here's how she got started. “I was desperate to get a good night's sleep after an unexpected crisis rocked my world in my mid-thirties. As a Pharma rep, I didn't have the luxury of “sleeping in” after staring at the clock all night. That's when I got my hands on a popular, physician-prescribed sleeping pill—because when you work in the Pharma field, it's not hard to score a pill for any ill.” This all-too-common scenario — woman can't sleep, doc says “I have just the thing”—resulted in reliance on Ambien, pharma name, Zolpidem. According to medlineplus.gov, “Zolpidem is used to treat insomnia (difficulty falling asleep or staying asleep). Zolpidem belongs to a class of medications called sedative-hypnotics. They go on to say, “Zolpidem may cause serious or possibly life-threatening sleep behaviors. Some people who took zolpidem got out of bed and drove their cars, prepared and ate food, had sex, made phone calls, sleep-walked, or were involved in other activities while not fully awake. After they woke up, these people were unable to remember what they had done.” Morgan goes on to say, “I didn't know that sleeping pills inhibit your ability to experience restorative sleep. Taking the pills may help you become unconscious, but sedation is not the same as sleep. I would wake up groggy, oftentimes to an empty box of cookies I didn't remember eating, and trudge through the morning until last night's pill would wear off. It's a miracle I never got behind the wheel in these fugue states.” So begins our conversation on how to sleep deeply and restoratively, without using prescription medications long term. Once Morgan made the decision to get off Ambien, she wanted to spread the word about these potentially dangerous meds and help other women find alternatives. We discussed the difference between deep sleep and being knocked out using Ambien and other sedative hypnotics. There are two main types of sedative-hypnotics – benzodiazepines and Z-drugs. Common benzodiazepines include Xanax (alprazolam), Librium (chlordiazepoxide), Valium (diazepam), and Ativan (lorazepam). Common Z-drugs include Ambien (zolpidem), Lunesta (eszopiclone), and Sonata (zaleplon). Thanks for this to https://www.healthinaging.org/tools-and-tips/ask-expert-sedative-hypnotic-drugs-and-related-medications (HealthInAging.org) We now know, in part thanks to the work of Matt Walker and colleagues, that of all the lifestyle habits we must pay attention to age in good health, none is as critical to the process as is sleep. Some of Morgan's tips mirror mine in https://rebelliouswellnessover50.com/power5/ (The Power of 5 work.) If you don't sleep well it's time to take stock of every single choice you make throughout the day. So much influences our sleep including, what and when we eat, blood sugar levels, how much or how little we move, stress, what we do or don't do to prepare for sleep, the lighting and temperature in our pre-sleep environment. Speaking of blood sugar, Morgan uses and recommends a https://www.nutrisense.io/?code=MORGANA (continuous blood sugar monitor from NutriSense.)What's that? It's a small device you stick onto your arm that monitors blood sugar levels throughout the day and night. The data is collected to an app on your phone. The idea is to see what foods, activities, and environmental influences push blood sugar levels up higher than normal or keep them high when they should come down to base level. I've not yet tried one but it's on my list to do before the end of the year. Why would you try one? If your insomnia is due to high blood sugar levels, even in part, and you know what's driving it, you can adjust what you are doing. Morgan also swears that her https://ouraring.com/ (Oura ring) has made a big difference in how she sleeps. It provides all kinds of data on your...
Segundo a Associação Brasileira do Sono, 65% dos brasileiros dormem mal e 10% têm insônia. Um remédio novo, o Lemborexant - que já é comercializado nos Estados Unidos e vai chegar ao Brasil - é a grande novidade que promete fazer muita gente voltar a dormir e dormir bem. O medicamento foi apontado como o mais eficaz e bem tolerado numa grande revisão feita por pesquisadores de Oxford e publicada na revista científica Nature. Encontrar um medicamento seguro e eficaz não é fácil. Um dos mais usados no Brasil, o Zolpidem, exige cautela dos usuários porque pode causar sonambulismo e perda de memória. Semana passada, um estudante de Campina Grande teve uma crise após o uso do medicamento e comprou um pacote de viagem para Buenos Aires por 9 mil reais! Outros remédios, como o Clonazepan, também muito populares, têm grande poder de causar dependência e podem aumentar problemas cognitivos. Quais são as opções de medicamentos para insônia que existem no mercado brasileiro? Como eles agem e que efeitos podem provocar? As mulheres precisam tomar mais cuidado? O que fazer pra não ficar dependente? Vamos ouvir duas especialistas no assunto: Dalva Poyares - neurologista, professora de medicina do sono na Universidade Federal de São Paulo (Unifesp) Helena Hachul - Ginecologista. Especialista em distúrbios de sono em mulheres Eu sou Michelle Loreto e remédios para insônia é o nosso tema de hoje no podcast do BE.
Repercute na internet o caso de um rapaz que afirma ter apresentado alucinação após tomar um medicamento. O jovem virou meme após postagem no Twitter em que afirma ter comprado sem saber dois pacotes de viagem no valor de 9 mil reais. Ele também teria se apresentado aos amigos como Neto da Rainha de Gênova. O farmacêutico Gabriel Freitas, consultor do Conselho Federal de Farmácia, esclarece que esse fármaco em questão, Hemitartarato de Zolpidem pode realmente causar esse tipo de reação adversa.
Today we talk about the drug Ambien and the effects it has on those taking the prescription to help them sleep better, or using it "off label". After listening in you may rethink taking the drug, but that will be your choice. Send us your stories at deadtotheworldpodcast@gmail.comRate and Review us on Podchaser and Apple iTunes
Neste episódio vamos falar sobre os principais fármacos utilizados no tratamento de insônia (e ansiedade). Vamos ver como eles agem no cérebro, quando são recomendados e quando NÃO são, assim como seus possíveis efeitos adversos. Vamos falar também do álcool e da Melatonina e, claro, o que é necessário fazer para uma pessoa conseguir voltar a dormir naturalmente SEM precisar de remédios! 00:00:00 - Vamos falar de benzodiazepínico, Fármacos Z, Álcool, Melatonina e como dormir SEM remédios 00:04:28 - Sinais químicos e mecanismos que nos deixam ALERTA ou com SONO 00:12:07 - Como a ANSIEDADE (e outra emoções) e ESTIMULANTES atrapalham o SONO 00:16:00 - Como os “remédios para dormir” funcionam 00:18:47 - Como os BENZODIAZEPÍNICOS (ex. Rivotril, Frontal, Lorax) agem no cérebro e quais são seus efeitos 00:22:50 - BENZODIAZEPINICOS no tratamento de ANSIEDADE e/ou INSÔNIA: tipos, quando são recomendados e efeitos adversos!!!! 00:35:42 - Os Benzodiazepínicos podem causar tolerância, depend6encia, abstinência e insônia rebote 00:39:55 - FÁRMACOS Z (ex. Zolpidem) no tratamento de INSÔNIA: tipos, efeitos e vantagens em comparação com Benzodiazepínicos. 00:43:00 - NENHUM remédio para dormir GERA um SONO tão bom e restaurador quanto o NATURAL (sem uso de remédios)!!! 00:52:50 - Fármacos para dormir e MORTALIDADE 00:56:56 - O padrão ouro do tratamento de INSÔNIA 00:59:37 - COMO voltar a dormir (bem) SEM REMÉDIOS! 01:14:27 - Como o álcool ATRAPALHA o sono 01:17:50 - Como a MELATONINA pode (ou não) ajudar no sono Lista de espera Masterclass SONO: https://bit.ly/3k419WI INSTA: https://bit.ly/profandrei TIKTOK: https://bit.ly/profandreineur0 E-MAIL: profandrei.neuro@gmail.com REFERÊNCIAS: 1) Meta-análises sobre a eficácia da suplementação com Melatonina: https://pubmed.ncbi.nlm.nih.gov/15649737/ https://pubmed.ncbi.nlm.nih.gov/23691095/ 2) Trabalho remédios x qualidade do sono: https://pubmed.ncbi.nlm.nih.gov/25922426/ 3) Trabalho sobre o impacto do aquecimento global no sono: https://www.sciencedirect.com/science/article/pii/S2590332222002093?via%3Dihub 4) Revisão sobre remédio pra dormir e mortalidade: https://f1000research.com/articles/5-918/v3 5) Site do Dr. Daniel Kripke (UC San Diego) sobre remédios para dormir: https://www.darksideofsleepingpills.com
Getting to the root of sleep struggles might take longer than popping a pill, but good sleep hygiene and bedtime habits are a healthier solution. Relying on Ambien or other sleep medicines for an extended period of time can have long-term side effects. JL and Mark talk about sleep and sleep aids; when to use them and when to try an alternative method.Tweet us your questions @jeanlucneptune or @marklewismd or email us at isitserious@offscrip.com or call us at 855-283-4666.SHOW NOTES: CDC Sleep guidelines - https://www.cdc.gov/sleep/about_sleep/how_much_sleep.htmlSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Welcome to the second* installment of our latest series all about sleep and cannabis. In today's episode we dive into the importance of nighttime rituals that involve winding down with weed, and offer some expert advice re: finding the best bedtime strain for you. So without further ado, cuddle up and give our latest sleep series episode a listen! *If you haven't listened to “Sleep 101: Why Better Sleep Starts with Cannabis,” we'd suggest giving that episode a listen first for some helpful background! SHOW NOTES Episode 77: Indica, Sativa, Hybrid: What They Really Mean Physiology, Glucose Metabolism, Assessment of Patterns of Potentially Unsafe Use of Zolpidem, Health Effects of Long Term Sleeping Pill Use, Understanding the Side Effects of Sleeping Pills, Insomnia, Cannabis Tolerance, Insomnia by Mayo Clinic, Sleep Basics, The Effects of Cannabinoid Administration on Sleep, Cannabis for Sleep: Short Term Benefit, Long Term Disruption? Hosted by Ellen Lee Scanlon Sign up for our newsletter at dothepot.com Follow us: IG: @dothepot FB: @dothepot Pinterest: @dothepot LinkedIn: How to Do the Pot Twitter: @dothepot --- Send in a voice message: https://anchor.fm/htdtp/message
It’s been said that JoAG is like listening in on a conversation at the pub, and friends, that’s what this one is. We were gonna talk about zoonotic diseases, but instead we end up deep into a spiral about great directors who kinda suck now and why that happens. Join us. Eavesdrop. Sidle up to as at the bar and interject your thoughts. Highlights:[0:00] CoRri tells Mark about the dangers of the sleep medication Ambien [24:00] We talk about our March mayhem, reflect on watching Piranha (1978), and discuss the next Marko’s Video Rants. Go submit your pick! [33:00] We start walking about what we watch and just gooooo [59:00] A conversation about Darkman spirals into a discussion about aging directors who’ve lost what made them great Stuff we referenced: The Bizarre Side Effects of Taking Ambien – https://www.healthline.com/health/side-effects-of-taking-ambien Roseanne’s Ambien story almost makes sense. – https://slate.com/technology/2018/05/roseannes-ambien-story-almost-makes-sense.html “I Did What?” Zolpidem and the Courts | Journal of the American Academy of Psychiatry and the Law – http://jaapl.org/content/39/4/535 The ‘Ambien Defense’ Has a Long, Dubious History | Time – https://time.com/5295281/ambien-defense-history/ Two Cases of Zolpidem-Associated Homicide – PMC – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505131/ Zolpidem: MedlinePlus Drug Information – https://medlineplus.gov/druginfo/meds/a693025.html
Melatonina? Terapia holística? Zolpidem? Esquece isso e foca no que realmente funciona! Veja aqui o que seria isso. Saiba mais sobre controlar a insônia e a ansiedade em https://controleaansiedade.com/
Heaven Falls Hard • A-Sun Amissa • Explosions in the Sky & David Wingo • Leila Abdul-Rauf • Sarram • Daxma • Anna Von Hausswolff • David Lynch • Theyrgy • Raphael Weinroth-Browne • Deeper Graves • Morbid Angel • Skullflower Heaven Falls Hard: "Safe Haven" taken from the album "The Mercy-Go-Round" A-Sun Amissa: "To the Ashes" taken from the album "Ceremony in the Stillness" Explosions in the Sky & David Wingo: "Passing Time" taken from the "Prince Avalanche" OST Leila Abdul-Rauf: "Distortions In Phantasy III: Suspension" taken from the album "Phantasiai" Sarram: "Diving Deep" taken from the album "Albero" Daxma: "Saudade" taken from the album "Unmarked Boxes" Anna Von Hausswolff: "Dolore Di Orsini" taken from the album "All Thoughts Fly" David Lynch: "The Line It Curves" taken from the album "The Big Dream" Theyrgy: "Dreamcatcher" taken from the album "Exit Strategies" Raphael Weinroth-Browne: "From Above" taken from the album "Worlds Within" Deeper Graves: "15000 Lives" taken from the album "The Colossal Sleep" Morbid Angel: "Dreaming" taken from the album "Domination" Skullflower: "Get The Horn" taken from the album "Last Shot At Heaven"
O hemitartarato de zolpidem está na classe dos medicamentos hipnóticos. Se a gente quiser ser mais preciso, ele é um agonista do receptor Gaba. No Brasil, também é conhecido pelo nome comercial de Stilnox. Nos Estados Unidos, Ambien.O zolpidem age direto nas sinapses do cérebro humano. Tem e incrível capacidade de ir lá no interruptor inexistente da nossa cachola e clic. Desligar. Ou seja, é basicamente um sonífero.Um sonífero que, apesar de extremamente eficaz contra insônia, traz uma série de riscos à saúde, especialmente se for usado de forma abusiva ou inadequada. O que tem acontecido bastante, uma vez que seu uso virou modinha entre jovens que costumam postar suas desventuras com o remédio nas redes sociais.– Colabore com a Rádio Escafandro e receba recompensas.Clique aqui.*****Episódio relacionado#37 - O sonho do SidartaMergulhe mais fundoGabiCriadora da conta @zolpidembotRosa HasanMédica neurologista, responsável pelo laboratório de sono e pelo ambulatório de sono do Instituto de Psiquiatria do HCFMUSP. Responsável pelo ambulatório do sono e pelo laboratório do sono da Faculdade de Medicina do ABCFicha técnicaConcepção, produção, roteiro, apresentação, sonorização e edição: Tomás ChiaveriniTrilha sonora tema: Paulo GamaMixagem: Vitor CoroaDesign das capas: Cláudia FurnariTrilha incidental: Blue Dots.
O hemitartarato de zolpidem está na classe dos medicamentos hipnóticos. Se a gente quiser ser mais preciso, ele é um agonista do receptor Gaba. No Brasil, também é conhecido pelo nome comercial de Stilnox. Nos Estados Unidos, Ambien. O zolpidem age direto nas sinapses do cérebro humano. Tem e incrível capacidade de ir lá no interruptor inexistente da nossa cachola e clic. Desligar. Ou seja, é basicamente um sonífero. Um sonífero que, apesar de extremamente eficaz contra insônia, traz uma série de riscos à saúde, especialmente se for usado de forma abusiva ou inadequada. O que tem acontecido bastante, uma vez que seu uso virou modinha entre jovens que costumam postar suas desventuras com o remédio nas redes sociais. – Colabore com a Rádio Escafandro e receba recompensas. Clique aqui. ***** Episódio relacionado #37 - O sonho do Sidarta Mergulhe mais fundo Capitalismo tardio e os fins do sono (link para compra) Entrevistados do episódio Gabi Criadora da conta @zolpidembot Rosa Hasan Médica neurologista, responsável pelo laboratório de sono e pelo ambulatório de sono do Instituto de Psiquiatria do HCFMUSP. Responsável pelo ambulatório do sono e pelo laboratório do sono da Faculdade de Medicina do ABC Ficha técnica Concepção, produção, roteiro, apresentação, sonorização e edição: Tomás Chiaverini Trilha sonora tema: Paulo Gama Mixagem: Vitor Coroa Design das capas: Cláudia Furnari Trilha incidental: Blue Dots.
BenzoZ können bei Schlafstörungen eine Option sein – wenn erste Maßnahmen nicht mehr helfen. Ein „EvidenzUpdate“ über gute diagnostische und therapeutische Pfade. Und über die Wahl zwischen Muster 16 und Privatrezept.
In this episode we talk about the three most popular sleep medications used in the non-benzodiazepine class. We'll discuss the risks inherent in these medications as well as the risk of addiction.
Roofies are more than just a nickname for one pill. It's a class of drugs. The most popular of them all, GHB aka Liquid G. GHB is showing up all over the world and is really popular among 20 and 30 year olds. Tune in to today's episode to hear all about the new roofie in town.
Você sabia que toda terça-feira tem aula ao vivo sobre diversos assuntos do ramo farmacêutico lá no meu canal no Youtube? Sim, isso mesmo! Toda terça às 20:00 horas eu dou uma aula nova, com assuntos novos! Ficou interessado e quer participar? Então cadastre seu e-mail clicando no link
What are the best treatment options for primary insomnia? What is the role of behavioral therapy and zolpidem? Faculty: Jim Phelps, M.D. Hosts: Jessica Diaz, M.D.; Flavio Guzman, M.D. Learn more about Premium Membership here Earn 0.5 CMEs: Quick Take Vol. 22 Effectiveness of Sequential Psychological and Medication Therapies for Insomnia Disorder: A Randomized Clinical Trial
Zolpidem is a hypnotic drug that selectively agonizes the benzodiazepine-1 receptor. It comes in multiple tablet forms as well as in a spray. The most common brand name zolpidem is identified with is Ambien. The most recognizable orally disintegrating tablet brand is Intermezzo. Zolpidem is used for short term treatment of sleep-onset and sleep-maintenance insomnia. It is important to transition patients off zolpidem to avoid symptoms of withdrawal. A commonly prescribed regimen for the immediate release tablet is 5 mg po immediately before bedtime allowing for 7-8 hours of uninterrupted sleep. Some factors to consider are females appear to have a higher sensitivity to the medication so lower doses should be used. This medication should not be used if a patient is pregnant due to the drug being able to cross the placenta. Data shows that the neonate is at severe risk and could be born with withdrawal symptoms. There is black box warning for Complex Sleep Behaviors which include sleep walking, sleep driving, or other activities being conducted while not fully awake which may lead to injury or death. The medication should not be taken with food since it will delay the onset of action. Go to DrugCardsDaily.com for episode show notes which consist of the drug summary, quiz, and link to the drug card for FREE! Please SUBSCRIBE, FOLLOW, and RATE on Spotify, Apple Podcasts, or wherever your favorite place to listen to podcasts are. The main goal is to go over the Top 200 Drugs with the occasional drug of interest. Also, if you'd like to say hello, suggest a drug, or leave some feedback I'd really appreciate hearing from you! Leave a voice message at anchor.fm/drugcardsdaily or find me on twitter @drugcardsdaily --- Send in a voice message: https://anchor.fm/drugcardsdaily/message
Clinical Journal of the American Society of Nephrology (CJASN)
Drs. Magdalene Assimon and Jennifer Flythe summarize findings from their study "Zolpidem versus Trazodone Initiation and the Risk of Fall-Related Fractures among Individuals Receiving Maintenance Hemodialysis."
Clinical Journal of the American Society of Nephrology (CJASN)
Drs. Magdalene Assimon and Jennifer Flythe summarize findings from their study "Zolpidem versus Trazodone Initiation and the Risk of Fall-Related Fractures among Individuals Receiving Maintenance Hemodialysis."
Rebecca has heard that high stress hormones cause insomnia and that it's hard to get them down, is this true? Jessica asks how harmful Zolpidem is. Lena is not sure she can do enough to protect herself from Covid-19. Cara was doing really well having worked with a sleep therapist until the day she graduated. Matt is temporarily living with his mother who just tested positive for Covid-19, what should he do to not worry around bedtime. Will bedtime restriction work for early morning awakenings? Gary asks. TinyTia wonders if alpha stimulators are a good idea and Malena asks what to do if you wake up when everyone else is sleeping. Do you have trouble sleeping? Can’t sleep? Have questions about insomnia or sleep? Please leave a comment or send me an email at daniel@insomniainsight.co and I will be happy to share my thoughts as a video or audio reply. If you want to connect elsewhere I’m on Twitter @ErichsenDaniel, Instagram @Erichsen.Daniel, Facebook as Daniel Erichsen. I have a blog at bedtyme.co. Here are some playlists that I hope you’ll find helpful. Core curriculum - a collection of the most important insights, a great place to start. https://www.youtube.com/playlist?list... Success stories - if you need hope and inspiration, this is for you. https://www.youtube.com/playlist?list... Insomnia insight - a list of every single episode. https://www.youtube.com/playlist?list... Talking insomnia - guests with insomnia or experts share their stories / tips. https://www.youtube.com/playlist?list... Hypnic jerks, sudden awareness of falling asleep and other common issues. https://www.youtube.com/playlist?list... Fatal insomnia - for those concerned about ffi and sfi. https://www.youtube.com/playlist?list... Best! This content does not constitute medical advice, diagnosis, or treatment, and should never replace any advice given to you by your physician or other qualified healthcare providers.
Matt wonders if Zolpidem while starting CBTi will make it difficult to build sleep confidence. Holland's insomnia has switched from sleep onset insomnia to sleep maintenance insomnia, what to do? Don asks how to deal with high cortisol and fight/flight response at night. Aproperlady is concerned that being on a medication can make the brain forget how to sleep without it. Jay has read about natural short sleepers, is that a thing? Do you have trouble sleeping? Can’t sleep? Have questions about insomnia or sleep? Please leave a comment or send me an email at daniel@insomniainsight.co and I will be happy to share my thoughts as a video or audio reply. If you want to connect elsewhere I’m on Twitter @ErichsenDaniel, Instagram @Erichsen.Daniel, Facebook as Daniel Erichsen. I have a blog at bedtyme.co. Here are some playlists that I hope you’ll find helpful. Core curriculum - a collection of the most important insights, a great place to start. https://www.youtube.com/playlist?list... Success stories - if you need hope and inspiration, this is for you. https://www.youtube.com/playlist?list... Insomnia insight - a list of every single episode. https://www.youtube.com/playlist?list... Talking insomnia - guests with insomnia or experts share their stories / tips. https://www.youtube.com/playlist?list... Hypnic jerks, sudden awareness of falling asleep and other common issues. https://www.youtube.com/playlist?list... Fatal insomnia - for those concerned about ffi and sfi. https://www.youtube.com/playlist?list... Best! This content does not constitute medical advice, diagnosis, or treatment, and should never replace any advice given to you by your physician or other qualified healthcare providers.
Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Zolpidem enhances the action of GABA which is an inhibitor neurotransmitter. Zolpidem metabolism can be impacted by the use of CYP3A4 inhibitors. Concentrations can rise on account of this potential interaction. It is important to remember to go slowly when tapering off zolpidem. Particularly in patients who have been on the drug for a long time or those who are on higher doses. Abnormal sleeping behaviors like sleep-walking, eating, or driving have been reported with zolpidem. Remember that CNS depressant drug interactions can happen with zolpidem. Take note of any other sedating medications prior to starting zolpidem.
Zolpidem (work in progress) by KnightVision
This episode I’m discussing a few artists like Joyner Lucas, EARTHGANG, young M.A., Big K.R.I.T.. etc. Also talk about a few anime’s I’ve been watching like fire force and dr. Stone.
Nesse episódio do PQU Podcast, mais um da série Fichário de psicofármacos, apresentamos dados de farmacologia clínica do Zolpidem, o hipnótico mais utilizado nas últimas décadas no tratamento de insônia. Seu uso é muito tranquilo se for feito de acordo com as recomendações, mas ele tem sido usado exagerada e indiscriminadamente, sem o devido critério, mais um sinal do quanto hoje em dia se tolera mal o desconforto próprio da existência, até mesmo algumas noites de insônia, ocorrência normal e até esperada em algumas circunstâncias.
Few things in life are more beneficial than a good night's sleep. But for millions of people, especially those in benzo withdrawal, this is easier said than done. Learn some tips and tricks which may help you get the rest you so desperately need. In today's episode, we'll tackle the withdrawal symptoms of insomnia and nightmares. We'll also answer a question on taper symptoms, discuss how long psychological symptoms may continue, and join D for a personal anniversary celebration. https://www.easinganxiety.com/post/the-restless-pursuit-of-rest-insomnia-in-benzo-withdrawal-bfp032Video ID: BFP032 Chapters 00:57 Introduction10:40 Mailbag21:20 Feature45:58 Moment of Peace Episode Summary Today, we are going to take a look at sleeping symptoms in benzo withdrawal. This includes insomnia and nightmares. We also will answer a couple of questions from the mailbag, and share one comment. In addition, D will share a personal anniversary regarding his own recovery. Resources The following resource links are provided as a courtesy to our listeners. They do not constitute an endorsement by Easing Anxiety of the resource or any recommendations or advice provided therein. MAILBAGTHE ASHTON MANUAL: https://benzo.org.uk/manual/FEATURE: Insomnia in Benzo WithdrawalAshton, C. Heather. Benzodiazepines: How They Work and How to Withdraw (aka The Ashton Manual). 2002. Accessed April 13, 2016. http://www.benzo.org.uk/manual.“Binge-watching television linked with insomnia and fatigue.” Spectator Health. August 15, 2017. Accessed August 15, 2017. https://health.spectator.co.uk/binge-watching-television-linked-with-insomnia-and-fatigue/.Exelmans, Liese, Jan Van den Bulck. “Binge Viewing, Sleep, and the Role of Pre-Sleep Arousal.” Journal of Clinical Sleep Medicine 15(08)(2017):1001-8. Accessed August 15, 2017. http://jcsm.aasm.org/viewabstract.aspx?pid=31062.Ford, D. “Epidemiologic study of sleep disturbances and psychiatric disorders. An opportunity for prevention?” JAMA262(11):1479-84. Accessed March 23, 2017. doi:10.1001/jama.262.11.1479.Foster, D E. Benzo Free: The World of Anti-Anxiety Drugs and the Reality of Withdrawal. Erie, Colorado: Denim Mountain Press, 2018. https://easinganxiety.com/book. Foster, Helen. “Not sleeping? Best insomnia cure could be ignoring it.” Daily Telegraph. September 20, 2017. Accessed October 1, 2017. http://www.dailytelegraph.com.au/lifestyle/health/body-soul-daily/not-sleeping-best-insomnia-cure-could-be-ignoring-it/news-story/0734f87ce37af05d024619d4d9beaff5.Gardner, R.S. Isaac. “Why Are Benzodiazepines and Z-Drugs Still Prescribed Indefinitely For Insomnia?” Brain Blogger. February 11, 2016. Accessed March 6, 2017. http://brainblogger.com/2016/02/11/why-are-benzodiazepines-and-z-drugs-still-prescribed-indefinitely-for-insomnia/.Lewin, Evelyn. “Worrying about insomnia may be worse than lack of sleep.” WAtoday. November 15, 2017. Accessed November 16,2017. https://www.watoday.com.au/lifestyle/health-and-wellness/worrying-about-insomnia-may-be-worse-than-lack-of-sleep-20171115-gzlsow.html.Pardini, Cassandra. “Melatonin Compared With Zolpidem for Hospital-Related Insomnia.” MPR. July 3, 2019. Accessed August 15, 2019. https://www.empr.com/home/news/melatonin-compared-with-zolpidem-for-hospital-related-insomnia/.Shahly, Victoria, et al. “The Associations of Insomnia With Costly Workplace Accidents and Errors: Results From the America Insomnia Survey.” JAMA Psychiatry 69(10)(October 2012):1054-63. Accessed April 6, 2018. https://jamanetwork.com/journals/jamapsychiatry/fullarticle/1370486.Spence, D. Warren, et al. “Acupuncture Increases Nocturnal Melatonin Secretion and Reduces Insomnia and Anxiety: A Preliminary Report.” Journal of Neuropsychiatry February 1, 2004. Accessed July 11, 2008. https://neuro.psychiatryonline.org/doi/full/10.1176/jnp.16.1.19.Stoianovici, Robyn, Luigi Burnetti, and Christopher D. Adams. “Comparison of Melatonin and Zolpidem for Sleep in an Academic Community Hospital: An Analysis of Patient Perception and Inpatient Outcomes.” Journal of Pharmacy Practice. June 25, 2019. Accessed August 15, 2019. https://doi.org/10.1177/0897190019851888.Tracy, Phillip. “Somnox: This Bean-Shaped Cuddle Robot Is Designed to Fight Insomnia.” DailyDot.com. November 24, 2017. Accessed November 25, 2017. https://www.dailydot.com/debug/somnox-robot-kickstarter/. The PodcastThe Benzo Free Podcast provides information, support, and community to those who struggle with the long-term effects of anxiety medications such as benzodiazepines (Xanax, Ativan, Klonopin, Valium) and Z-drugs (Ambien, Lunesta, Sonata). WEBSITE: https://www.easinganxiety.comMAILING LIST: https://www.easinganxiety.com/subscribe YOUTUBE: https://www.youtube.com/@easinganx DISCLAIMERAll content provided by Easing Anxiety is for general informational purposes only and should never be considered medical advice. Any health-related information provided is not a substitute for medical advice and should not be used to diagnose or treat health problems, or to prescribe any medical devices or other remedies. Never disregard medical advice or delay in seeking it. Please visit our website for our complete disclaimer at https://www.easinganxiety.com/disclaimer. CREDITSMusic provided / licensed by Storyblocks Audio — https://www.storyblocks.com Benzo Free Theme — Title: “Walk in the Park” — Artist: Neil Cross PRODUCTIONEasing Anxiety is produced by…Denim Mountain Presshttps://www.denimmountainpress.com ©2022 Denim Mountain Press – All Rights Reserved
The idea behind pretty much every bar is essentially the same: Create an enjoyable environment for people to come have drinks or food. This is our business. Maybe some bars don't play the music you like, some bars don't serve the food you like, some bars don't play the sports games you like, it's impossible to please everyone all the time, of course, but the idea is still pretty much the same. Unfortunately, sometimes guests have a different idea of what the bar is supposed to be. Some people go to bars to start fights and act out their aggression, some people go to bars to coerce women and men into having sex with them and some people use our bars as a platform to push their political agenda. This is an unfortunate reality that bartenders sometimes have to deal with, and in certain certain markets like Uptown Oakland, Calif., violence is commonplace. My guest today is Nate Olson. He's worked behind the bar for two decades all across the country: in Minneapolis, Miami, New Orleans and the San Francisco Bay Area. Nate currently manages a lovely Italian restaurant in Oakland called Lungomare. Nate has seen some shit during his tenure, he's had to deal with violence towards himself, his coworkers and between customers. He was managing Oakland's Make Westing bar during the incident last July that involved death threats, Proud Boys, riot police and protesters. We will dive more into this incident and other violent situations after the break. It is unfortunate and sad that acts of violence sometimes happen at our bars, and it's extremely hard to know what to do. Every situation is different, but hopefully if we hear more about what others have done in the past, we will be able to handle these situations better in the future. Nate had a lot of great advice about what worked for him and what he would do differently. Check out my interview with Nate in the player below, on this page or wherever podcasts are found. Honestly, I'm not an expert on violent situations and I've been fortunate myself to not be involved in very many. Every situation is totally different, which makes it so hard to know what to do. Experience helps, of course, but if the situation turns violent, it could be your last experience. The Bureau of Labor Statistics reported 138 fatalities in our industry in 2017. Many of those were the result of violence. Just a few weeks ago, four people were shot inside of the Halftime Sports Bar in downtown Oakland. My hope is that by learning from the experience of others we can better handle these situations ourselves, or even prevent them from happening altogether. Nate shared his experiences with some pretty traumatic violence. I want to get into these specific events a little bit more here. Date rape drugs and how to spot the signs Ambien, a prescription sleep aid, is one of the most common date rape drugs mixed with alcohol. Photo: WebMD Alcohol is the most common date rape drug. It lowers inhibitions, reduces coordination and makes people do stupid things. Alcohol is our business though, and most of us are pretty well aware of its affects and how to be safe about serving it. We know what to look out for when it comes to alcohol, but when alcohol is mixed with other drugs, things can get dangerous. A variety of different drugs are used in these situations and they come in different forms. Zolpidem, the sleep aid drug known as Ambien is the most common, according to the US Drug Enforcement Administration. Other drugs, including various benzodiazepines like Valium and Xanex, Rohypnol, and GHB and its derivatives have also been well documented. All of these drugs cause severe reactions when mixed with alcohol, including severe loss of coordination, inhibition, short term memory loss and in high enough doses, heart and respiratory failure. Nate spoke about a situation involving date rape drugs that he experienced while managing Make Westing. "A woman was totally fine, talking with me,
Tory and Mikah talk about a few medicinal sleep aids before interpreting three dreams from listeners. Featuring: house boats, murder scenes, oceans, backpacks, and a number of apocalypses. Notes and links Medicinal Sleep Aids Ambien an oral sedative and a nonbenzodiazepine does not cause racism helps you fall asleep more quickly, but isn't intended to help you stay asleep a gamma-aminobutyric acid (GABA) agonist, meaning it encourages production of GABA in the brain Ambien has some hypnotic side effects things you did on ambien - Reddit Ambien can cause dependence In very rare cases, Ambien has had some cognition-improving effect on individuals who have experienced brain damage. Antihistamines work by reducing or blocking histamines histamines are little chemicals created by your body that attach to histamine receptors on certain cells in your body histamine is created in the brain in histamine neurons. Histamine promotes wakefulness in the brain and is very effective at doing so. histamine acts on H1 receptors in the hypothalamus of the brain. antihistamines wiggle their way into the brain and keep histamine from connecting with those receptors, so your brain is like, "OK, time for sleeping now." newer, non-drowsy antihistamines affect the H2 receptors in the brain or don't cross the blood brain barrier at all. Melatonin Melatonin is a hormone produced by the pineal gland in our brain. It’s referred to as “the sleep hormone.” Melatonin production is controlled by the Suprachiasmatic Nuclei this magical region of the brain in the hypothalamus is connected to our eyesight and there are photosensitive cells in the nuclei. it's responsible for regulating our 24-hour circadian rhythm. between the neurons and the hormones it activates, it uses about 20,000 neurons to keep our shit running like clockwork. Melatonin helps kick your Stage 1 sleep into gear. You start to feel less alert and want to go to sleep. Melatonin production changes with time. shorter periods of production in the summer, longer periods in winter melatonin production drops with age, too. Studies show that Melatonin is a great coach for our body’s natural sleep-wake cycles. it may also shorten the time it takes you to fall asleep it may also improve sleep quality and increase amount of sleep overall Scientists at Ontario’s University of Guelph found that in more than 71 percent of melatonin supplements, the amount of melatonin was more than 10 percent different from what the product label indicated. some products contained as much as 83 percent less melatonin than was on the label other products contained as much as 478 percent more melatonin than was on the label Rozerem a melatonin agonist, meaning it encourages production of melatonin in the brain the only prescription sleep medication not classified as a controlled substance most don’t get the groggy hangover feeling you can sometimes get from other prescription sleep aids OK for long-term use, unlike drugs like Ambien as a prescription medication, it's held to higher standards and regulated better than something like melatonin supplements Dreams Listener Tyler: A dream about a boat house, a giant wall of water, a bathroom murder scene, and prophecy. Listener Brian: A dream about a boat, backpack swimmers, a wedding, and an ever-encroaching ocean. Listener Brad: Many dreams about many (creative) apocalypses. Send in your dreams: email: dreams@lucid.show site: lucid.show Follow us on Twitter: @Lucid_Podcast Sources https://americanaddictioncenters.org/withdrawal-timelines-treatments/ambien/ https://www.medicinenet.com/benzodiazepines_sleep-inducing-oral/article.htm#formulations_of_benzodiazepines http://medicationguide.ambien.com http://www.psychiatrist.com/JCP/article/Pages/2004/v65n08/v65n0816.aspx https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657033/ https://web.archive.org/web/20120410030254/http://www.nps.org.au/__data/assets/pdf_file/0011/59888/Zolpidem_position_statement_To_print.pdf https://www.ksl.com/index.php?nid=248&sid=588181 https://www.nytimes.com/2011/12/04/magazine/can-ambien-wake-minimally-conscious.html https://www.helpguide.org/articles/sleep/sleeping-pills-and-natural-sleep-aids.htm http://www.health.com/health/condition-article/0,,20189012,00.html https://www.livescience.com/41999-antihistamines-drowsy-benadryl-allergies.html https://www.ncbi.nlm.nih.gov/pubmed/20851648 https://www.ncbi.nlm.nih.gov/pubmed/24673474 https://www.psychologytoday.com/us/blog/sleep-newzzz/201709/how-melatonin-helps-you-sleep https://www.hopkinsmedicine.org/health/healthy-sleep/sleep-science/melatonin-for-sleep-does-it-work
Roseanne Barr Wrecks Career with Deadly Combination of Ambien and TwitterAmbien Has Always Been Dangerous. PERIOD. End of story.I gotta give CBS News Credit, they had many whistleblowing reports on Ambien in the past:CBS News Report#1https://www.youtube.com/watch?v=amAjJ_tgcsQCBS News Report #2https://www.youtube.com/watch?v=oSR3i6PcadkCBS News Report #3https://www.youtube.com/watch?v=aMt7I7quB_ACBS News Report #4https://www.youtube.com/watch?v=eCQQzvBZrgo[CNN Clip Used]https://www.youtube.com/watch?v=jg1h0V_OJFk
Roseanne Barr Wrecks Career with Deadly Combination of Ambien and TwitterAmbien Has Always Been Dangerous. PERIOD. End of story.I gotta give CBS News Credit, they had many whistleblowing reports on Ambien in the past:CBS News Report#1https://www.youtube.com/watch?v=amAjJ_tgcsQCBS News Report #2https://www.youtube.com/watch?v=oSR3i6PcadkCBS News Report #3https://www.youtube.com/watch?v=aMt7I7quB_ACBS News Report #4https://www.youtube.com/watch?v=eCQQzvBZrgo[CNN Clip Used]https://www.youtube.com/watch?v=jg1h0V_OJFk
Xanax, Lexomil, Prozac, Valium…Voici les psychotropes, médicaments qui agissent sur Psyché pour l’aider à calmer ses troubles. Si, de manière générale, les Français sont de grands consommateurs de médicaments, on retrouve parmi les 30 substances les plus achetées (tous médicaments confondus), 4 psychotropes : le Zolpidem, le xanax, le Zopiclone et le Paroxetine. Des antidépresseurs, des médicaments contre l’insomnie ou l’anxiété. 3 de ces 4 médicaments best-seller sont des benzodiazépines ou des dérivés de cette molécule – (le Zolpidem et le Zopiclone ne sont pas à proprement parler des benzodiazépines…
Xanax, Lexomil, Prozac, Valium…Voici les psychotropes, médicaments qui agissent sur Psyché pour l'aider à calmer ses troubles. Si, de manière générale, les Français sont de grands consommateurs de médicaments, on retrouve parmi les 30 substances les plus achetées (tous médicaments confondus), 4 psychotropes : le Zolpidem, le xanax, le Zopiclone et le Paroxetine. Des antidépresseurs, des médicaments contre l'insomnie ou l'anxiété. 3 de ces 4 médicaments best-seller sont des benzodiazépines ou des dérivés de cette molécule – (le Zolpidem et le Zopiclone ne sont pas à proprement parler des benzodiazépines et ont l'avantage de présenter moins d'inconvénients que ces derniers, notamment en termes d'effets secondaires et de dépendance – ndlr) Ces Benzodiazépines sont les psychotropes les plus consommés et les durée de prise dépassent les recommandations : la durée de prise moyenne est de 7 mois… pour une durée de prescription recommandée de 4 à 12 semaines. Des prises de médicaments parfois éloignées des recommandations, des situations de souffrance que les psychotropes soulagent mais ne guérissent pas, des interactions médicamenteuses et des effets secondaires : les psychotropes, pierre angulaire de la psychiatrie contemporaine – on dit aussi la psychopharmacologie – ces médicaments du cerveau questionnent. Pour comprendre ces situations et la place de la prescription médicamenteuse dans la psychiatrie, écoutons le point de vue des prescripteurs. Après 60 ans d'utilisation des psychotropes en médecine, quel bilan faire des médicaments de la psychiatrie ? InvitésJean-Marie Vanelle, Professeur des Universités et Praticien Hospitalier Psychiatre au CHU de Nantes.Caroline Victorri Vigneau, Maitre de Conférences à l'Université de Nantes et Praticien Hospitalier dans le service de pharmacologie clinique du CHU-Nantes. CréditsUne émission animée par Elliott Chaumont et Mathilde Robert, avec la participation de Barbara Chicotot, Valérie Fourgassié et Guillaume Mézières. A la technique, Claire Sizorn. Crédit photo : Assorted Medicine Pills in Caps ca. 2001
Wir sprechen in der Folge 008 (nicht wie aus Versehen gesagt 007) über den PsychCast bei Twitter und Facebook, die Frage der Woche (Was wäre, wenn Schlaf biologisch nicht mehr nötig wäre?), Skills, den Masernvirus, Sprichwörter zum Schlaf, die Zeitschrift "Schlaf" beim Schattauer Verlag, Schlafprobleme als gesundes Phänomen, historische Schlafrhythmen, richtige Schlafstörungen, Koffein, Hypnagoge Halluzinationen, Schlaflosigkeit, Vorgehensweise bei Schlafproblemen, den Einschlafen-Podcast, Schlafhygiene, Alkohol, Cola, Kaffee, Träume, Schlafphasen, Fragen an Jan Dreher aus Max Frisch "Fragebogen" und vieles mehr. (P.S.: Und noch ein kleines erratum: Zolpidem gibt es patentfrei, nicht, wie ich irrtümlich gesagt habe, rezeptfrei... Viel Spaß beim hören, Euer Jan)