Podcasts about cymbalta

Chris Eckfeldt: "GOD SUSPENDED ME"  | The Hopeaholics PodcastChris Eckfeldt's unforgettable journey through darkness to hope will grip your soul. In 2023, a catastrophic mountain biking accident in San Clemente shattered Chris's spine, robbing him of his legs and thrusting him into a world of unrelenting physical and emotional turmoil. Once an avid rider tearing down trails with the MTB Maniacs, he faced the stark reality of paralysis, his life forever altered in a single, harrowing moment. The protective “bubble” of rehab in Denver offered a temporary sanctuary, where logistics were managed and hope flickered. But returning home to the same streets and faces that once defined his vibrant life was a crushing awakening—every task, from bathroom access to car travel, became a labyrinth of adaptation. Job loss struck like a sledgehammer, stripping away his sense of purpose, while wrong medications, particularly Cymbalta, spiraled him into a vortex of anxiety and despair, fueling two suicide attempts that nearly ended his story. Yet, in the depths of that darkness, Chris found a lifeline. Through relentless self-advocacy, he secured the right medication—low-dose Wellbutrin—restoring clarity and stability. Bolstered by his wife Domini's unwavering support, who stood firm through fear and heartache, and a renewed faith that saw divine purpose in his survival, Chris began to rebuild. He discovered that his pain could light the way for others, not through grand gestures but through the raw, honest sharing of his journey.#TheHopeaholics #redemption #recovery #AlcoholAddiction #AddictionRecovery #wedorecover  #SobrietyJourney #MyStory #RecoveryIsPossible #Hope #wedorecover Join our patreon to get access to an EXTRA EPISODE every week of ‘Off the Record', exclusive content, a thriving recovery community, and opportunities to be featured on the podcast. https://patreon.com/TheHopeaholics Follow the Hopeaholics on our Socials:https://www.instagram.com/thehopeaholics https://linktr.ee/thehopeaholicsBuy Merch: https://thehopeaholics.myshopify.comVisit our Treatment Centers: https://www.hopebythesea.comIf you or a loved one needs help, please call or text 949-615-8588. We have the resources to treat mental health and addiction. Sponsored by the Infiniti Group LLC:https://www.infinitigroupllc.com Timestamps:00:06:19 - The Mountain Biking Accident00:09:01 - The Crash and Immediate Aftermath00:10:40 - Diagnosis of Spinal Injury00:11:18 - Realizing Paralysis00:17:32 - First Suicide Attempt00:18:25 - Second Suicide Attempt00:28:53 - Job Loss as a Catalyst00:29:44 - Divine Intervention in Survival00:32:50 - Rehab as a Protective Bubble00:33:01 - Overwhelm of Returning Home00:34:23 - Medication Struggles and Advocacy00:42:28 - Support System and Treatment Commitment

Chris and Dave (finally) put a bow on the 2024-25 Packers season. The fellas were on a Darkness Retreat following the painful opening round playoff loss to the eventual Super Bowl Champion Eagles, but with a steady IV drip of Cymbalta, the guys got up off the floor to record a season-ender. And, boy what a show it is! Well, it is actually more of the same nonsense as usual as Chris and Dave look back at 2024 and look ahead to what the Packers might (should?) do in 2025 as the off-season descends.  Patreon: https://www.patreon.com/packerstherapyPayPal: Packerstherapy@yahoo.comPosting its first show in 2005, Packers Therapy is the longest-running Packers podcast on the Internet. Hosts Chris and Dave began the show as a way of capturing the spirited chats the two co-workers had about the team around the office. The two have no pretense about being experts: they are just two opinionated shareholders who love the team, follow it closely, but don't always see the Packers fortunes eye to eye.The guys encourage comments and questions via their Twitter feed @PackersTherapy or email to packerstherapy@yahoo.com and read and respond to as many as they can during each show.Packers Therapy is a part of the Packers Talk family of podcasts, serving up five distinct podcasts to satisfy the most fervent of Packer fans. Variety is the spice of life, so subscribe to Packers Talk on Apple Podcasts, Spotify or wherever you get your podcasts. You can also follow Packers Talk on Twitter and Facebook. 

Dr Steve, Dr Scott, Lady Diagnosis, and Tacie discuss: Auto brewery syndrome Paparazzi Mushroom Tincture Motoric cognitive risk syndrome Fatigue and Alzheimer's FDA Warning re: GLP-1 weight loss drugs (can increase risk of aspiration) Walking pneumonia on rise? Cymbalta recall due to nitrosamines e. coli outbreak in fast food Light affecting circadian rhythm and pineal gland home brain stimulation for depression (non-pharmacologic) Please visit: simplyherbals.net/cbd-sinus-rinse (the best he's ever made. Seriously.) instagram.com/weirdmedicine (instagram by ahynesmedia.com!) x.com/weirdmedicine stuff.doctorsteve.com (it's back!) Watch for our new channel "Stitts on Gaming" coming soon! You can play along with us at Megabonanza.com! An actual legit site, never had an issue redeeming "sweepstakes coins" (i.e., real money) We also play at STAKE.US! Get free stuff (crypto site, let me know if you need help getting set up!) Do you love coffee? Jeremy can be a nut sometimes, but his coffee is serious business and seriously great Visit Coffee Brand Coffee from HERE and get a discount on small-batch roasted coffee beans, grinds, and K-cups CHECK OUT THE ROADIE COACH stringed instrument trainer! roadie.doctorsteve.com (the greatest gift for a guitarist or bassist! The robotic tuner!) see it here: stuff.doctorsteve.com/#roadie Also don't forget: Cameo.com/weirdmedicine (Book your old pal right now because he's cheap! "FLUID!") Most importantly! CHECK US OUT ON PATREON!  ALL NEW CONTENT! Robert Kelly, Mark Normand, Jim Norton, Gregg Hughes, Anthony Cumia, Joe DeRosa, Pete Davidson, Geno Bisconte, Cassie Black ("Safe Slut"). Stuff you will never hear on the main show ;-) Learn more about your ad choices. Visit podcastchoices.com/adchoices

I began my career in brand management at Procter & Gamble, after graduating from Miami University (Oxford, OH). My brand-building work spans across many brands in beauty, pet, family categories, as well as capability building in corporate marketing roles. A highlight of my time was when I led My Black is Beautiful at P&G, and I launched the“The Talk” campaign that won over 150 industry awards including 5 Cannes Lions and an Emmy in 2018.   I have also deepened my marketing experience within the Tech industry, leading brand marketing campaigns at Google, and consulting with advertisers to define and execute digital and multicultural-led marketing & media strategies.  Additionally, I spent time at Lilly in a consumer marketing role focused on multicultural patient innovation in communications, in which I partnered with key brands in the US Affiliate, and of note with the Cymbalta team to launch the first spanish-language TV copy for Cymbalta in the U.S.   Most recently, I led Brand Partnerships and B2B marketing at Canela Media.  When I'm not working and spending time with my children, I love to cook (soul ood is a favorite), read, and watch sports - especially women's gymnastics and football.  My service commitments include several activities/responsibilities as a life-long member of Quinn Chapel AME Church in Forest Park, OH and as a member of Alpha Kappa Alpha Sorority, Inc.  I am a Cincinnati, OH native and now also reside in New York City.

ttps://.neuropathyct.com Peripheral neuropathy, a condition resulting from damage to the peripheral nerves, often leads to chronic pain, tingling, and numbness. To manage these symptoms, medications such as Gabapentin (Neurontin), Pregabalin (Lyrica), and Duloxetine (Cymbalta) are frequently prescribed. While these drugs can offer significant relief, their use comes with a range of potential dangers and side effects that patients and healthcare providers must carefully consider. DizzinessFatigueDrowsinessLoss of coordinationPeripheral edema (swelling of extremities)NauseaVomitingBlurred visionTremorsWeight gainLess common but more serious side effects include:Mood changes (such as depression or anxiety)Suicidal thoughtsDifficulty breathingSevere allergic reactions (rash, itching, swelling, severe dizziness, trouble breathing)Severe muscle pain or weaknessGabapentin can also interact with other medications, so it's important to inform your healthcare provider of all drugs and supplements you are taking. Additionally, stopping gabapentin suddenly can lead to withdrawal symptoms, so it should be tapered off gradually under a doctor's supervision. Always consult with your healthcare provider for personalized advice and informationNeuropathy@CoreHealth551 Post RoadDarien CT 06820203-875-0846.This podcast welcomes your feedback here are several ways to reach out to me. If you have a topic you would like to hear about send me a message. I appreciate your listening. Dr. Brian Mc Kayhttps://twitter.com/DarienChiro/https://www.facebook.com/ChiropractorBrianMckayhttps://chiropractor-darien-dr-brian-mckay.business.sitehttps://podcasts.apple.com/us/podcast/not-just-chiropractor-for-stamford-darien-norwalk-new/id1503674397?uo=4Core Health Darien-Dr.Brian Mc Kay 551 Post RoadDarien CT 06820203-656-363641.0833695 -73.46652073GMP+87 Darien, Connecticuthttps://youtu.be/WpA__dDF0O041.0834196 -73.46423349999999https://darienchiropractor.comhttps://darienchiropractor.com/darien/darien-ct-understanding-pain/Find us on Social Mediahttps://chiropractor-darien-dr-brian-mckay.business.site https://www.youtube.com/channel/UCNHc0Hn85Iiet56oGUpX8rwhttps://docs.google.com/spreadsheets/d/1nJ9wlvg2Tne8257paDkkIBEyIz-oZZYy/edit#gid=517721981https://goo.gl/maps/js6hGWvcwHKBGCZ88https://www.youtube.com/my_videos?o=Uhttps://www.linkedin.com/in/darienchiropractorhttps://www.facebook.com/ChiropractorBrianMckayhttps://sites.google.com/view/corehealthdarien/https://sites.google.com/view/corehealthdarien/home

This man went through a terrible experience after taking the SNRI, Cymbalta...

Hello, friends!   In today's episode, we tackle two thought-provoking listener questions that may resonate with many of you:   Cymbalta Conundrum: A listener shares their experience with Cymbalta, a medication prescribed for panic disorder. They noticed feeling amazing on days they forgot to take the medication, leading them to wonder if they truly needed it. We explore the concept of conditioned compensatory response, the effects of medication on the body, and the importance of gradual tapering.   ADHD Focus Struggles: Another listener struggles with focus and motivation despite trying various medications and strategies. We discuss the complexities of ADHD, the importance of environmental adjustments, and techniques like mindfulness, Pomodoro intervals, and accountability to improve focus and productivity.   As always, you can send me questions to duffthepsych@gmail.com and find the full show notes for this episode at http://duffthepsych.com/episode394   ---   Take care of your social battery with BetterHelp! Their online therapy platform offers flexible scheduling and matching with licensed therapists. Get 10% off your first month with the code "duff" at http://betterhelp.com/duff  

Join us as we discuss another medication in our SNRI series: Duloxetine, which goes by the brand name 'Cymbalta.'

Description: Co-host Ryan Piansky, a graduate student and patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and co-host Holly Knotowicz, a speech-language pathologist living with EoE, who serves on APFED's Health Sciences Advisory Council, speak with Moises Velasquez-Manoff, a health and science writer living with EoE. He is a contributing writer for the New York Times Magazine. He writes about the human microbiome and its impact on health, as well as climate, COVID-19, and other health and science topics. In this episode, Ryan and Hollyinterview Moises Velasquez-Manoff about his New York Times Magazine article and his search for help with his burning esophagus. They discuss his journey living with EoE, how he got diagnosed, and the treatments that help manage his symptoms. Moises speaks of various misdiagnoses he received that didn't address his issues. After reflux was ruled out by a series of three tests, a biopsy during an endoscopy indicated EoE. Now on treatment, Moises is feeling much better.    Listen in for a powerful story of a decades-long search for help. Disclaimer: The information provided in this podcast is designed to support, not replace the relationship that exists between listeners and their healthcare providers. Opinions, information, and recommendations shared in this podcast are not a substitute for medical advice. Decisions related to medical care should be made with your healthcare provider. Opinions and views of guests and co-hosts are their own.   Key Takeaways: [:50] Co-host Ryan Piansky welcomes co-host Holly Knotowicz. Holly introduces Moises Velasquez-Manoff, a health and science writer living with eosinophilic esophagitis (EoE). He recently wrote  an article that was published in NY Times Magazine entitled, “The Mystery of My Burning Esophagus,” in which he documented his journey and diagnosis of EoE.   [1:51] Eosinophilic esophagitis (EoE) is a rare chronic allergic inflammatory disease of the esophagus. It is part of a complex group of diseases known as eosinophilic gastrointestinal disorders or EGIDs.   [2:05] Approximately one out of 2,000 people of all ages and ethnic backgrounds [in the U.S] are diagnosed with EoE, and people with EoE commonly have other allergic diseases, such as rhinitis, asthma, or eczema.   [2:20] Moises has had asthma for as long as he can remember. It was worse when he was a child and he sort of grew out of it. In adulthood, it was exercise-induced asthma. He has been allergic to sesame and peanuts for his whole life. They make him vomit. He has had eczema, hay fever, and alopecia areata. [3:43] Moises has had problems with his esophagus since his 20s. He is 49 now and only got diagnosed with EoE about two years ago after his burning pain became very bad. It took about a year to rule out reflux, first by using high-dose proton pump inhibitors (PPIs). While on the medication, he still felt the horrible burning pain. He also had unusually bad side effects from the PPIs.   [5:25] After eight weeks of PPIs, an endoscopy showed his symptoms were almost gone. Moises believed he had reflux, but he still had the burning. His gastroenterologist suggested an alternative diagnosis, esophageal hypersensitivity, a pain syndrome from years of inflammation.    [8:21] Moises went to a second doctor who was an expert on EoE. They did a series of tests to rule out reflux. He did the Bravo PH test or reflux, a peristalsis test, a tube that was left in for 48 hours, and a barium swallow test. Each test was uncomfortable. These tests ruled out reflux.   [12:11] The doctor then believed it was esophageal hypersensitivity. The treatment was Cymbalta, an anti-depressant that also dampens pain signals. Moises was able to start eating again and started putting on weight that he had lost. A year after he stopped taking the PPIs, an endoscopy gave him the diagnosis of EoE.   [15:48] Reading Moises's article triggered many memories and emotions for Holly. She experienced symptoms since she was a baby and saw around 13 specialists before she received a diagnosis of EoE in her early 20s. By that time her eosinophil levels were out of control and her esophagus was so rigid she needed several dilations. [18:01] Moises had seen a gastroenterologist for reflux years ago and then two more doctors to get his EoE diagnosis. It was extreme pain that influenced him to seek the diagnosis. He also saw an ENT about sinus headaches, and he believes they were related to his EoE. He finally went to a doctor that specializes in EoE, just in case.   [23:08] Today, Moises manages his EoE with an off-label use of the asthma medicine budesonide taken twice a day. He mixes the solution into honey and drinks it, the honey helps the medicine stick to his esophagus. Moises worries about potential side effects as it is a steroid but at small doses.   [25:32] Ryan has taken the systemic steroids hydrocortisone and prednisone, as topical steroids were not effective for him. He was also on a restricted diet throughout his childhood. The diets didn't clear up his EoE; the only thing that helped was high-dose steroids until he began taking a biologic after being diagnosed with eosinophilic asthma.    [28:56] The treatment Moises is taking for EoE is localized. There shouldn't be any systemic effect. He believes if he took a biologic, he may see improvements in his other allergic conditions, such as eczema and his sinus condition.   [27:17] When his esophageal burning feeling was at its worst, Moises felt like he was suffocating. Doctors couldn't explain it to him, but a research scientist told him that sometimes problems in one internal organ, like the esophagus, can confuse the brain stem, so it reads the problem as coming from another organ, like the lungs or the heart.   [29:23] What helped with Moises's gasping attacks was the neuromodulating medicine, the anti-depressant, which changed how the nervous system perceives what's happening, lowered the ability for pain signals to be transmitted, and calmed his nerves.   [30:53] Ryan talks about drugs being prescribed off-label when there is anecdotal evidence that they can improve symptoms of other disorders. Some EoE patients use the asthma medicine budesonide as a topical treatment of the esophagus. It is mixed into a slurry with Splenda and swallowed. Dupilumab was originally approved to treat eczema and has recently been approved to treat EoE.   [31:40] Ryan is on benralizumab, a biologic, for eosinophilic asthma but as a side effect, it has also been  helping his EoE. He doesn't need systemic steroids anymore for his EoE. After seeing positive benefits from the biologic, he weaned off the steroids. His parents, who are doctors and involved in APFED, helped him through the process.   [34:40] Moises tells how he came to write the article for New York Times Magazine. While he was suffering, he was not considering writing about it. When he finally got his diagnosis and was feeling better, he read an article another science writer published about their journey with a pain condition and was inspired to help other people by writing about his own journey. His first draft  was more intense than the finished piece.   [37:09] Holly describes the article as very powerful. She felt she was going through it with Moises. She could feel what he was describing as he searched for answers. She appreciates him writing it. Moises says people have written to him from around the world that related to his story.   [40:43] Some even asked Moises about where they could find an EoE specialists, and Ryan mentions APFED's Specialist Finder. To find a specialist who treats eosinophilic disorders, go to APFED.org/specialists. Also, please check out Moises's article in these show notes.   [41:19] As a science writer, Moises has written a lot about the microbiome and its relationship to allergic disease and autoimmune disease before he noticed that this was happening to him. He had written a book, An Epidemic of Absence, 11 years ago about the root cause of these debilitating disorders and why allergies are increasing.   [42:51] Moises believes that the human microbiome has been impoverished by our modern environment and diets and that has led to an increased risk of allergic conditions. Moises gives the example of European farmers, who live in a rich microbial environment and have fewer allergic and autoimmune conditions.   [44:39] Moises says the research also shows that antibiotics early in life increase the risk of asthma, EoE, inflammatory bowel disease, and colon cancer. The more you take, the greater your risk. They have done research with animals, knocking out key microbes and seeing an increase in these diseases.   [45:33] H. Pylori is associated with ulcers and stomach cancer, but everyone used to have it, and it is common in the developing world. Research indicates that h. pylori changes how your immune system works. Unless you kill it with antibiotics, you have it for the rest of your life. If you have h. pylori, your EoE risk goes down.   [46:32] If you are breastfed, that also reduces your risk of EoE. Breastfeeding is thought to cultivate a healthy colony of microbes in the infant's gut. Moises credits the microbial deprivation hypothesis for the increase of allergies and autoimmune disorders. There won't be a treatment for microbial deprivation anytime soon.   [47:18] Holly and Ryan thank Moises Velasquez-Manoff for coming on the podcast and allowing them to interview him today about his patient experience and background. Moises thinks it's crazy how much good evidence there is that EoE has increased in prevalence. Unpublished results show that EoE incidence is approaching 1 in 1,000.   [48:45] To learn more about eosinophilic esophagitis, visit apfed.org/eoe. To find a specialist, visit apfed.org/specialists. Ryan recommends reading Moises's article. To connect with others impacted by eosinophilic diseases, join APFED's online community on the Inspire Network at apfed.org/connections.   [49:13] Ryan and Holly thank Moises Velasquez-Manoff again for joining them and invite listeners to read Moises's article. They close by thanking APFED's education partners, linked below, for supporting this episode.   Mentioned in This Episode: NYT Magazine article by Moises Velasquez-Manoff: “The Mystery of My Burning Esophagus” Early-life environmental exposures interact with genetic susceptibility variants in pediatric patients with eosinophilic esophagitis American Partnership for Eosinophilic Disorders (APFED) APFED on YouTube, Twitter, Facebook, Pinterest, Instagram Real Talk: Eosinophilic Diseases Podcast   Education Partners: This episode of APFED's podcast is brought to you thanks to the support of AstraZeneca, Bristol Myers Squibb, Sanofi, and Regeneron.   Tweetables: “I have had problems with my esophagus probably since my 20s but I only got diagnosed [with EoE] about two years ago after things started getting really bad.” — Moises Velasquez-Manoff   “I could not tolerate the PPIs, even though they worked very well to lower my eosinophil counts. But I could not handle the side effects. So we moved to swallowed budesonide slurry. … an off-label treatment.” — Moises Velasquez-Manoff   “Science takes a long time, sometimes.” — Moises Velasquez-Manoff   About Moises Velasquez-Manoff Moises Velasquez-Manoff is a contributing writer for The New York Times Magazine and author of An Epidemic of Absence: A New Way Of Understanding Allergies And Autoimmune Diseases. He's written a lot about the human microbiome and its impact on health, as well as climate, COVID-19, and other health and science topics. He lives in California. Website: Moisesvm.com NYT Magazine article: “The Mystery of My Burning Esophagus”

Dr. Jeffrey James discusses Hypothyroidism with Dr. Ben Weitz. [If you enjoy this podcast, please give us a rating and review on Apple Podcasts, so more people will find The Rational Wellness Podcast. Also check out the video version on my WeitzChiro YouTube page.]    Podcast Highlights 3:17  Hashimoto's thyroiditis is the most common form of low functioning thyroid or hypothyroidism.  Dr. James noted that he has seen hundreds of women suffering with hypothyroidism and most of these women don't even get tested for Hashimoto's, since from the perspective of conventional medicine, if the woman has low functioning thyroid/high TSH levels, they will be treated with Synthroid or levothyroxine, which is synthetic thyroid hormone.  If it has an autoimmune origin, it doesn't change the pharmaceutical outcome.  But if you have Hashimoto's thyroiditis you have an immune system problem rather than a primary thyroid problem. We need to try to understand what would cause your immune system to dysregulate and want to attack your own body tissues?  Unfortunately, once you have one autoimmune disorder, you're 50% more likely to develop another one.  Dr. James explained that a lot of women complain that they're exhausted, they're putting on weight, they've got brain fog, they're losing their hair, they're constipated, their skin is dry, they've got brain fog, they have this constellation of symptoms, and they're cold.  When they go to their doctor, out comes the prescription for Synthroid.  Unfortunately a majority of women end up back in their doctor's office after a few months or a few years and they don't feel any better.  Their primary MD or endocrinologist then tries to dial in their TSH.  If they are depressed, then they get prescribed an antidepressant like Effexor or Cymbalta. If they have headaches, they get prescribed Imitrex.  If their blood pressure goes up, they are prescribed antihypertensive medications like Lisinopril or Amlopidipine or hydrochlorothiazide.  Dr. James sees a lot of these women who feel like they are not being seen or their complaints are not being addressed by their physician.  9:10  Functional Medicine practitioners are not simply treating each symptom with a pharmaceutical drug to ameliorate that symptom but are looking at your underlying metabolism, physiology, endocrinology as well as the root causes of the autoimmunity that is often driving these imbalances that can often be corrected with diet and lifestyle changes.  The patient with hypothyroidism could have an underlying GI infection or a biotoxin illness. They could have a genetic susceptibility to not being able to process mycotoxins that are either in their environment or that are in their foods that they're eating. They could have a Lyme infection. They could have a viral infection or a gut infection, a parasite or a bacterial infection in their gut that's driving an immunological response.  Any of these things can create a low level inflammatory response that can affect thyroid production, conversion, or uptake, all of which create symptoms that are very similar.  From a Functional Medicine perspective we want to see which way the physiology is tilting and we want to see if their lab values are optimal and not just normal or not.  11:05  The medical system in our country where once per year you go in for a physical exam with very minimal testing only to look for a pharmaceutical intervention is a failed system. Just look at how poor the health of our country is.  We need to test more widely to see how well our bodies are functioning.  For thyroid, we need to look at not just TSH but total T4 and T3, free T4 and Free T3, and reverse T3 as well as the thyroid antibodies. We need to trace everything back to the mitochondria of the cell and how our bodies produce energy.  We eat a meal and breathe some oxygen in and that glucose and oxygen mashes up against the mitochondria to produce ATP.

Join InpharmD as we discuss the data on perioperative duloxetine (Cymbalta) during orthopedic surgery for pain reduction.  Interested in the full data response? Read here! 

For chronic migraine sufferers, there's a progression of migraine medications - first your doctor is going to start with the triptans, or now, perhaps the oral CGRP antagonists like Nurtec or Ubrelvy. But once those start to fail you, and you have to take more than is advised, your doctor is going to put you on daily preventative medication. Usually you'll start with things like propranolol or Topamax. But once those start to fail you - then your doctor is going to want to add in antidepressants like Amitriptyline or Nortriptyline - or maybe even Prozac, Wellbutrin, or Cymbalta. But are antidepressants treating the root cause of your migraines or just suppressing the symptoms? Do you really have an Amitriptyline deficiency? In this podcast, Dr. Leslie and Mari go pretty deep into the lack of efficacy of these meds and the problems that many women have when they want to get off these meds. And - as always - they talk about the 3 things you need to do instead to restore and maintain your health – because when we are in a state of health – our body doesn't generate migraines. Finally, Dr. Leslie shares some profound information about how her health was destroyed when she took a suppressive medication and her journey of recovery and restoration. Here are the links to other resources we talked about today: Free training on why drugs stop working eventually: https://www.drlesliecisar.com/StopWorking Podcast on why medications cause side effects: https://www.drlesliecisar.com/podcasts/healing-migraines-naturally/episodes/2147771700 Podcast on why drugs stop working: https://www.drlesliecisar.com/podcasts/healing-migraines-naturally/episodes/2147736839 Are you ready to get off the migraine rollercoaster and rediscover a migraine free life? Let's see if I can help. Schedule your free migraine consult call here: https://www.drlesliecisar.com/apply Stay connected: Join my free Facebook group: https://www.facebook.com/groups/healingmigrainesnaturally Check out my website: https://www.drlesliecisar.com/ Want to learn more? Check out my free trainings especially for women with migraines: https://www.drlesliecisar.com/free-resources

Clare and Cheryl share tips for how to cope with periods of no diagnosis or changing diagnosis. Clare also provides insights from her unique perspective as someone diagnosed with autism as an adult, soon after her myofascial pain syndrome diagnosis.Cheryl and Clare discuss the importance of perseverance in seeking help, building a personalized treatment plan, and ways to find joy in the midst of chronic illness while accepting that it's okay to feel sad or angry too.  The episode concludes with a discussion about how pain, brain fog, anxiety, and burnout are hard, but support is out there and can make a big difference in living well despite the challenges.Episode at a glance:Journey to diagnosis of myofascial pain syndrome and autism: getting referred to a variety of specialists to troubleshoot symptoms that mimic other conditions, learning to unmask and cope with pain, brain fog, anxiety, and burnoutBuilding a personalized treatment toolbox: currently incorporating pharmaceutical medication with integrative treatment. Physical therapy and exercise with gentle movement, yoga, and weight training, Cymbalta for depression and chronic painFinding joy: Find a community where you can learn new things and have compassionate and caring support. Don't forget to find joy in the “little things”, like cozy blankets or a TV show / movie / book to escape to.Advice for undiagnosed patients: You're not crazy! The gray area is scary, but it won't last forever. Keep an open mind, and know it's okay to feel sad and angry. Coping with a change in diagnosis: Clare's tips from her experience having her diagnosis changed: being open to new possibilities, advocating for yourself, and being realistic about what doctors knowLiving well despite chronic illness: Getting to a place where you're friends with your body - not fighting against it but rather acknowledging what your body has survived. Medical disclaimer:All content found on Arthritis Life public channels was created for generalized informational purposes only. The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment.Episode SponsorsRheum to THRIVE, an online course & support group program Cheryl created to help people with rheumatic disease go from overwhelmed, confused and alone to confident, supported and connected. Learn more here!For full episode Details, Links, Video & TranscriptionGo to the Arthritis Life Website: www.MyArthritisLife.Net (episode page coming soon!)

Neuropathy@CoreHealth551 Post Road Suite 1Darien CT 06820203-875-0846Https://neuropathyct.comNeuropathy@CoreHealth is Fairfield County's leading provider of neuropathic pain solutions. We offer cutting-edge therapy to get you some relief from painful burning sensations in your feet and hands. We do not prescribe medications because we know they do not help relieve your neuropathic pain. In many cases, the medications like gabapentin, Lyrica, or Cymbalta make things worse for you. We have helped people with many different types of Neuropathy;Chemo-Induced Peripheral NeuropathyDiabetic Peripheral NeuropathyAlcohol NeuropathyChronic Nerve PainTreatment times vary by the severity of your presenting neuropathy. We will teach you how to do several therapies at home. Our program has helped many residents of Fairfield get more out of life and perhaps we can help you. We offer a Thermal Imaging Scan for $47 dollars to determine if you are getting enough blood flow to the nerves in your hand or feet. From there we start to properly assess which therapies to suit you and get the best outcomes.watch more  about neuropathy hereThis podcast welcomes your feedback here are several ways to reach out to me. If you have a topic you would like to hear about send me a message. I appreciate your listening. Dr. Brian Mc Kayhttps://twitter.com/DarienChiro/https://www.facebook.com/ChiropractorBrianMckayhttps://chiropractor-darien-dr-brian-mckay.business.sitehttps://podcasts.apple.com/us/podcast/not-just-chiropractor-for-stamford-darien-norwalk-new/id1503674397?uo=4

“I'd like to try Lyrica, but I worry about if I ever had to come off. Should I try it?” For today's Ask The Coach episode, I'm answering this question sent in by Sarah in the UK. When treating fibromyalgia, we have to attack it from two sides. The first is addressing the fibromyalgia itself and the amplification of pain signals; the second is treating the pain that your fibromyalgia amplifies. In most cases, fibromyalgia medications are more helpful than harmful and can be a valuable tool to break the pain cycle. That said, the question of medications is complex and impossible to cover in detail in a podcast episode. Tami's primary focus for this answer will be on fibromyalgia medications that address the amplification of pain signals, how they work, and the most important aspects you'll want to consider. In this episode, Tami discusses the FDA-approved medications for fibromyalgia, the fact that no single drug is capable of managing all fibromyalgia symptoms, Tami's two-pronged approach to treating fibromyalgia, the main goal of fibromyalgia medications, Lyrica's history and previous versions, how Lyrica and Neurontin work to reduce our experience of our pain, common side effects of Lyrica, physical dependency versus addiction, how serotonin and norepinephrine affect pain levels, why the anti-depressants Savella and Cymbalta also help to address fibromyalgia symptoms, the mode of action of other anti-depressants that are sometimes prescribed for fibromyalgia, Cymbalta is known for being challenging to come off of, the importance of very slowly weaning off of medications, the gradual process Tami used when she was ready to come off of her medications, why we hear more stories about negative experiences, the fact that there's no morality in taking medication, and more.   Note: This episode is not meant to be medical advice. Every person and every situation is unique. The information you learn in this episode should be shared and discussed with your own healthcare providers. To learn more about the resources mentioned in this episode, visit the show notes. For daily doses of hope, inspiration, and practical advice, join Tami on Facebook or Instagram. Need a good book to read? Download Tami's books for free. Ready to take back control of your life and health? Schedule a complimentary consultation with a Certified Fibromyalgia Coach®.

We're back after Jim's trip to Montreal and Bobby's Trip to Nashville.  We go way long this episode and talk about a bunch of random topics (see below) - We talk therapy, childhood trauma, Reddit fights, inappropriate family requests, weight watcher points, and Cymbalta. Like, subscribe, and share with your friends.head to our youtube for more and to watch this episode live (releasing late 8/24)!https://www.youtube.com/watch?v=7M2FA2rjYg4READ THE REDDIT POST HERE FROM BOBBY's STORYTHE STROKES ALBUM YOU HAVE TO LISTEN TO  InstagramTwitterBobby's Only FansKeywords: MontrealPayment plans strippers male strippers private dance BJHJTravel Behavior Bathrooms In Montreal Nashville Bachelorette Parties Party Wagons Peddle Wagons Party Peddle Wagons Tractors Drunk Belligerent in public The Strokes Red Hot Chili Peppers Julian Casablancas Albert Hammond Jr Mental Health Demi Lovato Reddit ModeratorsReligion Talks Bad Moderators Salty Gays Bad Gays Mean Gays Religious GaysPower Trip Gays Inappropriate Family Moments Smoking NurseSubway Sandwich Therapy Better Help Childhood Trauma Childhood Sexual Abuse Bobby spills the tea about why he is the way he is Cymbalta Switch Weight watchers points Pop Tarts Are the worst This episode is sponsored by our Patreon. For $2 a month, you can help us continue to grow and create Patron: https://www.patreon.com/Notwellpodcast#gaypodcast #podcast #gay #lgbtq #queerpodcast #lgbt #lgbtpodcast #lgbtqpodcast #gaypodcaster #queer#instagay #podcasts  #podcasting #gaylife  #pride #lesbian #bhfyp #gaycomedy #comedypodcast #comedy #nyc #614 #shesnotdoingsowell #reddit #nashville #montreal #malestripper #bachelorette Support the show

Episode 330 Wellness Wednesday episode in which we talk about Vertigo types, Cymbalta, Wellbutrin, Nightshades good or bad, Healthy Frozen Foods and other stuff for Multiple Sclerosis Health and MS. Send comments, questions and tips to kevintheduckpool@gmail.com please help us out by rating and reviewing us and telling a friend. Also check out audio and video versions of Crimson Cowl Comic Club & Under the Cowl podcasts. A fun variety of great people talk comic books, entertainment or whatever and you can see or hear me on many episodes of those podcasts as well with many more great episodes to come out in the future. --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app --- Send in a voice message: https://anchor.fm/kevin-kleinhans/message Support this podcast: https://anchor.fm/kevin-kleinhans/support

In this episode, Dr. Christopher Tookey is joined by Dr. Zach April to discuss the members of the SNRI class of medicines. This includes duloxetine (Cymbalta), venlafaxine (Effexor), desvenlafaxine (Pristiq) and others.  A disclaimer, we're providing general guidance but everyone is different and you should always discuss with your health care professional management of any disease and therapy before trying anything you discover from a source on the internet (including this podcast) 

EP223 Comic Book talk about Lucy Claire Redemption #1 to 3 of 5, Ruins of Ravencroft Dracula #1. Multiple Sclerosis talk about comparing Wellbutrin vs Cymbalta for Depression and MS issues. Send questions, comments and tips to kevintheduckpool@gmail.com please rate, review and tell a friend. --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app --- Send in a voice message: https://anchor.fm/kevin-kleinhans/message Support this podcast: https://anchor.fm/kevin-kleinhans/support

Duloxetine is used in a wide variety of indications. It can be used in treating fibromyalgia, chronic musculoskeletal pain, and neuropathic pain due to diabetes mellitus. It is also used in treating mood disorders such as generalized anxiety disorder and major unipolar depressive disorder. The general dosing range for duloxetine is 30-60 mg PO qd. Although the max dose is 120 mg per day, therapeutic benefits do not appear evident past 60 mg per day. Duloxetine works through strong inhibition of neuronal serotonin and norepinephrine reuptake along with weak inhibition of dopamine reuptake. There is reduced bioavailability in patients who smoke cigarettes with a 33% reduction of bioavailability. When discontinuing therapy duloxetine should be titrated down over 2-4 weeks. There is a black box warning for suicidality and risks vs benefits should be weighted when being used in children and adolescents. When taking duloxetine capsules should be taken whole and should not be opened. Go to DrugCardsDaily.com for my episode show notes which will contain a drug summary, quiz, and a link to FREE drug card sheets. SUBSCRIBE on Spotify or Apple Podcasts or search for us on your favorite place to listen to podcasts. I will go over the Top 100-200 Drugs as well as throwing in some recently released drugs that peak my interest. Also, if you'd like to say hello, suggest a drug, or leave any constructive feedback on the show I'd really appreciate it! Leave a voice message at anchor.fm/drugcardsdaily or message us through twitter @drugcardsdaily --- Send in a voice message: https://anchor.fm/drugcardsdaily/message

Teen Mom was a cornucopia of Leah's tumor-Ted-Talks, y'all! She ain't gonna die, but she will try to pass off Boston Market buns as her own. After a little parenting advice for Jade and praise for Briana, per usual because we forever stan the DeJesus Women, we recall the many lost seasons of The Real World. Amanda has uncovered a hidden gem moment in the archives, but not after suffering through 4 hours of Cymbalta commercials! Finally, we talk about our mutual love (ok, lust) for MTV True Life Crime's Dometi Pongo. He could be 19, he could be 42, and he could be the man of our naughtiest dreams. SUBSCRIBE & LEAVE US A 5-STAR REVIEW! IG @welovetohatepod Twitter @lovetohatepod WE LOVE TO HATE TV on Patreon www.patreon.com/lovetohatetv *This week: Family Therapy & Seeking Sister Wife Season 1 TOTAL REQUEST PODCAST on Patreon www.patreon.com/trpod *This week: Mama June Not to Hot & Carpool Karaoke with James Cordon (Celine, Madonna, Broadway Stars & Friends Reunion Backstage episodes)

Dr. Stephen Brannan, Chief Medical Officer at Karuna Therapeutics discusses positive data recently published in the New England Journal of Medicine from their Phase 2 EMERGENT-1 clinical trial evaluating KarXT in adults with schizophrenia. The publication builds on previously reported Phase 2 trial results in which KarXT demonstrated clinically meaningful and statistically significant improvements in treating the positive and negative symptoms of schizophrenia. Dr. Brannan talks about how Karuna is taking a new approach to treating schizophrenia, the disease burden of schizophrenia and the unmet need among patients for a differentiated treatment option that is safe and minimizes side effects. Dr. Brannan is a neuroscience drug development expert who has held senior positions overseeing both clinical development and medical affairs with more than 15 years of industry experience. Previously, Dr. Brannan was the Therapeutic Head of Neuroscience at Takeda and Vice President for Clinical Research and Medical Affairs at Forum Pharmaceuticals. Dr. Brannan has been active in the development of multiple important central nervous system treatments including Cymbalta®, Exelon Patch®, Trintellix®, and Vagal Nerve Stimulation for Treatment Resistant Depression while holding various senior roles at Forum, Takeda, Novartis, Cyberonics, and Eli Lilly. His experience includes drug development, registration, medical affairs, launch, and lifecycle management across psychiatry and neurology programs. Dr. Brannan is a member of several scientific societies and groups, including ACNP, ISCTM (member of the Executive and Scientific Program Committees), ISCDD, AARR, IOM Neuroforum, and CNS Summit (founding member and member of the Leadership Council).Prior to joining the pharmaceutical industry, Dr. Brannan worked on the faculty at the University of Texas Health Science Center at San Antonio (UTHSCSA) where he specialized in seeing mood and anxiety disorder patients, ran a clinical research unit, and did neuroimaging research at the Research Imaging Center.Dr. Brannan trained in psychiatry at UTHSCSA and holds an M.D. from the University of Texas Health Science Center at Dallas (Southwestern Medical School). He has over 40 publications and routinely gives invited talks and presentations at industry conferences. #KarunaTherapeutics #EMERGENT1 #Schizophrenia

Tramadol has shown major drug interactions with medications such as Ambien (zolpidem), Cymbalta (duloxetine), Flexeril (cyclobenzaprine), gabapentin, hydrocodone, Lyrica (pregabalin), Norco (acetaminophen / hydrocodone), Percocet (acetaminophen / oxycodone), Suboxone (buprenorphine / naloxone), Xanax (alprazolam),  and Zoloft (sertraline).https://recoverypartnernetwork.com/drug/opioid/tramadol-addiction

In a study conducted in 2006, it had been found that people who took Cymbalta experienced a significant weight loss in the short-term. However, it also showed modest weight gain in some trials.https://recoverypartnernetwork.com/drug/stimulants/duloxetine-addiction

It's highly recommended to take Cymbalta at the same time every day. Although some chose to take it in the morning, if it makes you feel drowsy, it is better to be taken in the evening.https://recoverypartnernetwork.com/drug/stimulants/duloxetine-addiction

It is best to consult your doctor before taking any sleep aid along with Cymbalta to prevent negative drug interactions.https://recoverypartnernetwork.com/drug/stimulants/duloxetine-addiction

It is not recommended to take Cymbalta within five days before, or fourteen days after taking an MAO inhibitor, such as methylene blue injection, isocarboxazid, phenelzine, selegiline, linezolid, rasagiline, or tranylcypromine.https://recoverypartnernetwork.com/drug/stimulants/duloxetine-addiction

Missing a dose may result in an individual experiencing withdrawal symptoms such as vomiting, feeling dizzy, headaches, nightmares, irritability, nausea, and prickling or tingling sensations on the skin.https://recoverypartnernetwork.com/drug/stimulants/duloxetine-addiction

The manufacturers warn that Cymbalta could result in liver damage, skin reactions, and abnormal bleeding. It can also result in serotonin syndrome, which can be a fatal condition that causes agitation hallucinations and even lead to coma.https://recoverypartnernetwork.com/drug/stimulants/duloxetine-addiction

People don't take Cymbalta to get high, in the way they take LSD or marijuana.https://recoverypartnernetwork.com/drug/stimulants/duloxetine-addiction

Cymbalta normally takes 2 to 4 weeks to work. It may take longer if you're taking it for nerve pain. https://recoverypartnernetwork.com/drug/stimulants/duloxetine-addiction

Cymbalta can cause certain individuals to experience the opposite effects, such as restlessness and tension, leading to anger and hostility. The drug can result in frustration, irritability, and a lack of patience in some patients.https://recoverypartnernetwork.com/drug/stimulants/duloxetine-addiction

Cymbalta can help alleviate anxiety and improve the mood by slowing the absorption of neurotransmitters by brain cells. https://recoverypartnernetwork.com/drug/stimulants/duloxetine-addiction

It has been found that Cymbalta was well tolerated and safe for elderly patients with major depressive disorder.https://recoverypartnernetwork.com/drug/stimulants/duloxetine-addiction

In clinical trials, Cymbalta significantly and quickly improved pain. More than half of the patients with fibromyalgia felt much better within one week. Pain relief may be greater in patients who also have existing depression, although those without depression also showed a significant improvement in symptoms.https://recoverypartnernetwork.com/drug/stimulants/duloxetine-addiction

Cymbalta is used for the treatment of anxiety and depression. It also helps relieve nerve pain in people with arthritis, chronic back pain, fibromyalgia, or diabetes.https://recoverypartnernetwork.com/drug/stimulants/duloxetine-addiction

When Cymbalta is discontinued, an individual can experience anger, irritability, debilitating brain zaps, extreme mood swings, physical and neurological problems that can go on for weeks, and even months.https://recoverypartnernetwork.com/drug/stimulants/duloxetine-addiction

Common side effects of Cymbalta include headaches, nausea, and dry mouth. There have been reported cases where patients have suffered liver damage, abnormal bleeding, suicidal thoughts and behavior.https://recoverypartnernetwork.com/drug/stimulants/duloxetine-addiction

There is a high risk of getting serotonin syndrome if an individual consumes a lot of coffee, cola, or other caffeinated drinks whilst taking Cymbalta.https://recoverypartnernetwork.com/drug/stimulants/duloxetine-addiction

People living with multiple sclerosis often experience chronic numbness, burning, tingling and pins-and-needles sensations. In a recent study, 70% of people with MS reported numbness and tingling, and 55% reported pain associated with relapses. MS neurologists explain typical symptoms for brain and spinal cord MS attacks compared to a pinched nerve in the back (like sciatica) or neuropathy. Lhermitte's sign (shocks down the spine when moving neck) and Uhthoff's phenomenon (numbness when overheated) are covered since frequently the first symptoms of multiple sclerosis. Options for relief from burning, tingling and pins-and-needles reviewed including medications such as Neurontin (gabapentin), Lyrica (pregabalin), Elavil (amitriptyline) and Cymbalta (duloxetine). Painful MS syndromes including trigeminal neuralgia, MS hug, and flexor and extensor spasms are reviewed with numerous treatment options. MS experts also share options to alleviate painful muscle cramps and spasms as well as musculoskeletal pain, such as low back pain. The podcast aims to provide awareness and options for relief so that people living with MS can better communicate with their doctors to improve their care. Barry Singer MD, Director of The MS Center for Innovations in Care, interviews: Mitzi Joi Williams MD, a MS neurologist and the founder and CEO of  Joi Life Wellness Group Multiple Sclerosis Center. Dr. Williams completed her neurology residency (including serving as chief resident) and multiple sclerosis fellowship at Georgia Health Sciences University (formerly MCG) in Augusta, GA. She is the author of MS Made Simple: The Essential Guide to Understanding Your Multiple Sclerosis Diagnosis. Brandon Beaber MD, an MS neurologist at Kaiser Permanente in Los Angeles. He completed his neurology residency at Kaiser Permanente’s Los Angeles Medical Center (LAMC) and fellowship in multiple sclerosis and neuroimmunology at University of Southern California. He authored Resilience in the Face of Multiple Sclerosis and regularly posts educational videos for people living with MS on his YouTube channel. Visit mslivingwell.org for more information. Share your MS story on ICanWithMS.org

What should you do when you feel creepy crawlers going up and down your leg at night? Have you been kept awake at night because of leg pain? You might have peripheral neuropathy. It is a painful annoying problem that affects people with diabetes or people after they undergo chemotherapy. Essentially what happens is that the nerves in your legs or hands start to lose sensitivity. When this happens your brain is searching for feedback from the nerves and it is not receiving enough feedback. The toxicity of the chemotherapy eats away tat the nerve covering causing the sensations of pain or loss of feelings. For diabetics, too much glucose in their blood eats away at the nerve covering. Since both underlying conditions are serious peripheral neuropathy is usually treated with medications like Lyrica or Cymbalta. In some cases, these drugs mitigate the symptoms but come with a cost. The chemotherapy patients and diabetics are already on medications for the primary diseases so another medication makes it harder for the body to work efficiently. Quite often a side effect of the neuropathy medications is weight gain. The primary symptoms of peripheral neuropathy are universal across the main three types of peripheral neuropathy diabetes caused neuropathy, chemo-induced peripheral neuropathy, and alcoholic neuropathy. The is a valuable tool called the Michigan Neuropathy Screening Instrument that was developed by the University of Michigan to help self assess neuropathy. The Michigan Neuropathy Screening Instrument (MNSI) is used to assess distal symmetrical peripheral neuropathy in diabetes. It includes two separate assessments: a 15-item self-administered questionnaire and a lower extremity examination that includes inspection and assessment of vibratory sensation and ankle reflexes. It is helpful for people who suspect they have neuropathy to gather more information before seeing their doctor. Neuropathy@CoreHealth relies on the self-assessment and the examination part of the MNSI to customize a suitable treatment protocol. There are several key components to the neuropathy program at Neuropathy@CoreHealth. As I see it the addition of EWOT ( exercise with oxygen therapy)has made a substantial impact on results. It is important to understand that every living thing in your body requires oxygen, glucose, and stimulation to survive. Most neuropathy patients have a compromised immune system. The addition of oxygen is a tremendous boost to the healing process when combined with proper nerve stimulation. Adequate glucose regulation is a basic fundamental building block to resolving peripheral neuropathy.

AHHH!!! I can't believe this is the 100th episode!!! Thank you all so much for listening to The V Hive, supporting this content and sharing it with your friends, family, co-workers, colleagues and more. I'm eternally grateful and so beyond excited to share this episode with you. It begins with a short solo segment, where I discuss several important life updates, such as how I got off the medication Cymbalta this past summer, my decision to go back to school to become a therapist, and lastly, all about the most amazing candles The V Hive just launched! Following this.... my boyfriend Dylan makes a special guest appearance! I ask him a bunch of questions about our relationship and then we get into a listener Q&A, where he answers all of your questions. I hope you enjoy this episode and once again, thank you for listening! xoxoxo ________ You can purchase The V Hive candle here: https://www.thevhive.com/shop/hand-poured-soy-candle ________ If you want to get in touch with The V Hive, please send an e-mail to info@thevhive.com. ________ Follow The V Hive: INSTAGRAM - @thevhive TWITTER - @thevhive_ FACEBOOK - @thevhivemedia WEBSITE - www.thevhive.com

Have you started to feel a burning sensation in your legs and feet? Have you had your blood sugar checked and found it to be on the high side? You may have what is known as peripheral neuropathy. If you are diabetic some people call it diabetic foot pain. The nerves stop communicating with the brain. If you are old enough to remember the loud beep you would hear when you left the phone off the hook, in a sense that is what the brain is doing in cases of peripheral neuropathy. The brain is looking for sensory feedback that it is not getting from the nerves in your feet. The longer it goes without sensory input the greater the pain will become.Neuropathy@CoreHealth specializes in a modern approach to treating peripheral neuropathy. One treatment that most people overlook is oxygen therapy for neuropathy. Typically, your well-meaning doctor will take out their prescription pad and write a script for gabapentin, Lyrica, or Cymbalta. These drugs are usually for seizures. Their side effects include weight gain and brain fog. So what are your options?The first thing you need to do is to educate yourself. Neuropathy is rarely an orphan symptom. It is most often a result of diabetes or from exposure to toxins like chemotherapy. What happens in the nerves need three things to work properly. The nerves require oxygen, glucose, and proper stimulation. All of these critical requirements are necessary for the nerves to function properly. When they don’t you can expect balance issues along with numbness, burning, searing pain in the feet and hands. The feet and hands are furthest from the heart and will be affected by neuropathy.Oxygen therapy has been helpful to stimulate angiogenesis which is the production of blood vessels. It stands to reason that increased blood flow with more blood vessels will tackle oxygenation issues faster. Then it is easier to address glucose issues to further healing. When nerves are deprived of oxygen Lyrica and Cymbalta are ineffective. Neuropathy over a long period of time.Oxygen therapy provided by Neuropathy@CoreHealth uses a special method to deplete oxygen levels. Hold on you might think this is bad. What happens is that the brain is looking for 02. After several minutes of exercise, the person then receives a jolt of 02 with a super concentration. This stimulates more blood vessel creation. Now the body is able to repair and heal at a faster rate reversing many of the painful symptoms associated with peripheral neuropathy. Some people will opt for hyperbaric 02 therapy, and yes this is an effective method of oxygen therapy but way more expensive way to help with neuropathic pain.

Kris...AKA my mom...shares openly, honestly, and vulnerably about her journey to losing 32 pounds + the catalyst that started it all, her experience with getting off the medication, Cymbalta (commonly used to treat anxiety, depression, and chronic pain), and everything that has changed in her life as a result. Connect with me here: Instagram: flowwiththegrowpodcast Instagram: sophia_dawn41 Facebook: Sophia Dawn Nehlich-Arobba

You may have heard me talk about all the strains and joint issues I used to deal with. MRIs, x-rays, rehab, it was harrowing and frustrating.  The root cause was undiagnosed anxiety. I was literally frying my tendons, joints and ligaments. I'm better now that Cymbalta has the anxiety under control, but back then I sought out cryotherapy and other things high level athletes to for what's called hyper wellness.  We finally have a place for that here! Restore at Levis Commons. 

Until I started doing this podcast, I was mostly ignorant to the extent of the harm sometimes caused by psychiatric and antibiotic medications. In spite of my own 2 week experience with disabling withdrawal symptoms from an antidepressant 20 years ago, and contemporary reports of withdrawal symptoms from friends and clients, I still had no idea how pervasive - and sometimes permanent - these brain injuries were. As frightening as that was to learn, the prescriptions for psychiatric medication for depression and anxiety have soared in during the COVID pandemic.  And let’s face it folks, we are still in the early stages of the pandemic - if we get blue skies with double rainbows we may have a vaccine in 18 months, but that’s really wishful thinking - the global economy has taken an unprecedented hit, and that means many people’s jobs and financial security are going to be at further risk. This will only add to the feelings of anxiety -- but let’s be clear, it is normal to feel anxious about how the world is suddenly changing in so many ways. Learning coping skills, having strategies to feel more safe in an unknown future, and using supportive relationships are natural ways to feel better about feeling anxious. In this episode, we hear what happened to Jocelyn Pedersen after taking a benzodiazepine for less than a week. Jocelyn was so physically sick from the benzo brain injury, she had to spend much of the time horizontal on the floor with her baby while her neighbour’s helped with household chores. Jocelyn’s body was a complete mess: she couldn’t sleep, eat, watch tv, read, her bowels were dysfunctional and she was losing weight fast. That’s just the start of Jocelyn’s journey with benzodiazepine medications -- a medication journey, as Jocelyn describes, that goes through madness. Jocelyn’s health care experience is a textbook example of how the medical system pushes psychiatric medications without understanding how the meds can cause brain injury. This often leads to doctors denying side effects or withdrawal symptoms, effectively gaslighting the patient, psychologizing physical symptoms, and pathologizing human emotions. It was a long arduous road for Jocelyn to get back to her usual high functioning self, and along the way she started sharing her experiences and what she learned and now Jocelyn has a large following on social media. On her YouTube channel Benzo Brains, Jocelyn shares real world information about benzodiazepines and strategies on successfully managing the withdrawal symptoms. Jocelyn has just written a memoir about her experiences with benzos and the health care system called “Seeds of Hope: A Journey Through Medication and Madness Toward Meaning”. Available on Amazon: https://t.co/267G0VaBiz?amp=1 Connect with Jocelyn Pedersen: People can pre-order Seeds of Hope: A Journey Through Medication and Madness Toward Meaning through moongladepress.com and when it's released June 1st on Amazon.com: https://t.co/267G0VaBiz?amp=1My channel is YouTube.com/c/BenzoBrainsSome other helpful resources are benzoreform.orgbenzoinfo.combenzo.org.uk/manualcouncilforsustainablehealing.org SHOW NOTES:   About Jocelyn Pedersen: After experiencing a severe injury to her brain and body from prescription medications, Jocelyn co-founded the non-profit, Benzodiazepine Information Coalition. She is a speaker at CME's and continuing education courses for doctors and healthcare providers on the dangers of benzodiazepines and how to help patients safely withdraw. Jocelyn is also subject in the upcoming As Prescribed documentary film and the author of Seeds of Hope: a Journey through medication and madness toward meaning. When she's not busy managing her Benzo Brains YouTube channel or serving as an advisor to The Alliance for Benzodiazepine Best Practices and The Council for Sustainable Healing, you can find her rocking out to big band music and forcing her kids to watch MGM musicals with her. 0:06:00 Jocelyn grew up in Pueblo, Colorado and her childhood was mixture of good and bad things, mental and physical abuse - but also grew up with a lot of spiritual support at Church of Jesus Christ of Later Day Saints and it stabilized her and taught her to overcome 0:07:00 Jocelyn got an academic scholarship to Brigham Young University so she moved to Utah and she loved college and graduated with a BS (Bachelor of Science) in childhood educations - college was a way to escape and re-start her life 0:08:00 Jocelyn got married and they moved to North Carolina and they had their first baby, but he passed away, so they decided to move closer to family for support and moved to Utah 0:09:00 Jocelyn started teaching at a local school for 2 years until she got pregnant again - she writes about her experience in her memoir that will be released in June: "Seeds of Hope: A Journey through medication and madness toward meaning" -- a couple of years later she had another baby, a girl to go with a boy 0:10:00 Jocelyn's father was a chiropractor so she grew up with a healthy distrust of allo medicine - but her story really starts when Jocelyn sought out a sleeping pill from her doctor - her baby daughter was in the hospital with meningitis, and then her toddler son was admitted to the hospital twice, so Jocelyn was not getting enough sleep - the economy was bad at the time, her husband was out of work 0:11:00 The doctor prescribed Ambien and assured Jocelyn it wouldn't pass through her breast milk to her baby - Jocelyn doesn't like taking medications, but thought she'd take it temporarily to get back into her sleep cycle 0:12:00 But within a couple of days, Jocelyn could tell her baby daughter was being affected by the Ambien - after 5 or 6 days Jocelyn stopped the Ambien and that's when things fell apart and her insomnia got much worse, she had ringing in her ears, running to the bathroom all the time, couldn't eat, losing weight, couldn't read a book, watch tv, and suddenly also had pain and couldn't even go for a walk 0:13:00 Jocelyn had a bunch of tests done but they all came back normal, so no explanation, except being told 'you have post partum depression', or 'you're having a nervous breakdwon', or 'you have anxiety' - but Jocelyn knew about depression from the death of her first baby, and this wasn't that 0:14:00 After about 4 months of literally lying on the floor with her baby and neighbours coming by to help - Jocelyn had been a high energy person: running, yoga, working out - but then she started to get suicidal thoughts 0:15:00 Jocelyn was told by the doctor she had major depressive disorder and an anxiety disorder and was given Effexor and Ativan - the first day she took the meds she slept well for the first time in 4 months - only later would Jocelyn realize that Ativan is practically the same as Ambien 0:16:00 So the Ativan stabilized the injury from the Ambien - originally Jocelyn was only to take the Ativan for a brief period, but the doctor increased the dose to 2 mg - 'it was like magic', Jocelyn felt better, like her old self, except for the pain, which was diagnosed as Fibromyalgia, and she was given Cymbalta for the pain - so for the most port Jocelyn was able to lead a normal life, she was a believer that she must have needed the meds 0:17:00 Jocelyn had studied and learned a lot about natural medicine and didn't like the idea of continuing to take Cymbalta, and it put weight on her 0:18:00 But the doctor would say, 'don't stop the Cymbalta until you've stopped the Ativan, now Lorazepam - but every time she tried to cut down, her symptoms would get worse, she couldn't sleep - so she stayed on them for another 3 years - but eventually tried to wean off again - she did stop progesterone cold turkey and got really sick 0:19:00 Her blood pressure sky rocketed, she gained a lot of weight, and falling asleep in the middle of the day - so she cold turkeyed it and the first time she experienced full on crazy, shaking all the time, and couldn't function 0:20:00 Jocelyn realized later the Cymbalta had really messed with her blood sugar and that's why she had put on so much weight - Jocelyn successfully weaned of the Cymbalta, but was still taking Lorazepam at night, but she and her husband wanted to have another baby but the literature said that Lorazepam could cause birth defects - they decided to go ahead and try to have another baby and that Jocelyn would try to taper off the Lorazepam 0:21:00 But Jocelyn later learned it doesn't really cause birth defects, but can cause of miscarriages if stopped to fast - Jocelyn did get pregnant and started to taper by 1/8th 0:22:00 Just cutting an 1/8th of a mg caused intense disabling symptoms: couldn't shower, read, watch tv, losing weight, and anxiety of a whole other dimension 0:23:00 It was torture, and then she had to cut the dose again, and then again - by the time Jocelyn got to half way she was ready to give up and kill herself because she couldn't handle the unending torture - luckily her husband started researching online - because Jocelyn couldn't - and found BenzoBuddies.org and Benzo.org.uk and he found the Ashton Manual, which a lot of people use to withdraw 0:24:00 They realized that Jocelyn wasn't crazy and that a lot of people were having the same experiences - and Jocelyn was probably tapering too fast - Ativan has a half life, so Jocelyn would experience sudden symptom onsets daily - so she switched to a longer lasting benzo to complete her taper 0:25:00 At the time, Jocelyn was too sick to go to the doctor - the next time she saw a doctor was at the ER when she thought she was having a miscarriage - they brought the Ashton Manual and requested Valium to stabilize Jocelyn, the doctor was resistant but finally agreed 0:26:00 The Valium provided some relief, but it was still hell and she didn't feel like she was going to take her own life - her family has seen Jocelyn struggle with Ambien withdrawal a few years before, and hearing the testimonials of others, helped them all to understand 0:27:00 Jocelyn had been drug injured with Ambien, but misdiagnosed with anxiety and depression - Jocelyn's doctor, a friend of the family, did not recognize withdrawal symptoms of Ambien 0:28:00 Jocelyn did have a miscarriage, which she is thankful for in some ways as she wasn't well enough to take care of a newborn at the time - Jocelyn continued to taper 0:29:00 Jocelyn tried various versions of tapering before discovering water titration, which she shows how to do on her YouTube channel - she had learned that in Facebook support groups - Jocelyn did reach out to mainstream medicine, she has a chapter in her book called 'Physician Heal Thyself' - all the doctors thought they knew about withdrawal, but none of them did, and none of them had read the Ashton Manual 0:30:00 One doctor told Jocelyn that she just couldn't handle being a Mom and should take some Prozac - the only doctor who was reasonable was Jocelyn's family doctor, but all he was willing to do was to prescribe the Valium 0:31:00 But when he was gone and Jocelyn had to deal with one of the other providers at his clinic, she was given the 3rd degree every time - it took Jocelyn about 18 months to taper off 13 mg dose of Valium - the newer benzos are many multiples more powerful then Valium, yet its the the Valium doctors are hesitant to prescribe 0:32:00 Jocelyn had to learn to accept where she was during the taper, that she had a brain injury - she also had support with the kids during the day, when her son started back to school... 0:33:00 she reached out to people in her church community and a different family came over each day to help her - Jocelyn does not know how she could have managed without community support because her husband was working 2 jobs 0:34:00 The big turning point for Jocelyn was finding a functional medicine doctor, a ND (Naturopathic Doctor) - she found one in her area and helped her with her benzo belly - he did tests that allopathic doctors don't do 0:35:00 He was able to pinpoint deficiencies - she started on a high protein diet because she was hypoglecemic - after about a week on his protocol Jocelyn started improving a lot, sleeping well 0:36:00 Then her son was prescribed an antibiotic and it injured him - it was like deja vu: once again no doctor is believing them - turns out her son developed an autoimmune illness and is allergic to everything - he was a normal boy, running and playing, then suddenly he's in a wheelchair and crying out in pain every few minutes 0:37:00 The paedeatric allergist said her son always had the autoimmune illness, refused to believe it was caused by an antibiotic - but the functional medicine doctor was able to help cut down on the inflammation and allergic reactions, but they are still figuring it out - he has a lot of trauma from that, and from a Mom who was disabled twice in his life - Jocelyn had to learn not to give power to health providers, and to heal herself 0:38:00 Yoga, meditation, diet, stem cell therapy for trigeminal pain -- nerve pain in her face -- it literally hurt to breath - the stem cell was very helpful, but she has to go back every 4 months or so as the pain comes back 0:39:00 How can someone help you if they don't even believe you? -- some doctors are open, but plenty are just closed minded 0:40:00 During her taper, Jocelyn was asked to be a moderator of a Facebook group, so she helped people find resources - then another friend asked her start another group to help people apply for disability or medical malpractice suits or correct medical records - Jocelyn realized they needed some 'weight' behind them, as they were 'just' sick patients, so Jocelyn suggested they start a non-profit 0:41:00 The Benzodiazepine Information Coalition - but then her son got sick and she had to step back to care for and home school him - but it was toward the end of her taper that she made her first Youtube video, just for her friends in the support group - and it got lots of shares - then when she was frustrated with doctors she made another video and that was picked up by Mad in America, and things just picked up 0:42:00 Her videos help people with brain injuries and their families get the support then needed - her Youtube channel is Benzo Brains - Jocelyn is doing really well. now, living life fully - she does get more stressed out physically 0:43:00 Her body is kind of delicate now, but she is really happy, with peace and joy - but if she doesn't get enough sleep or eat write, a dark blanket descends on her brain, but she knows it is only temporary - but it is painful having a son who is still suffering, but she's not coming from a place of fear 0:44:00 Jocelyn believes the suicidal thoughts that came from withdrawal are product of the medications causing the repeated thought 'kill yourself, kill yourself, kill yourself' 0:45:00 Most of the people dealing with withdrawal are good people, just doing what your doctor told you - Jocelyn was asked to speak in 2017 at the benzodaizipine medical symposium for doctors 0:46:00 Jocelyn met a lot of wonderful people, including a woman, a benzo survivor, who asked Jocelyn to write a book - initially Jocelyn declined but then thought it could be a good tool to get the message out there 0:47:00 It took a while to write while taking care of kids and her own healing journey, but it will be published June 1st - Seeds of Hope: A journey through madness, medication and meaning - she wants to give people hope that are in the same situation 0:48:00 The publisher approached Jocelyn to write the book - some of her benzo awareness efforts have been black balled by google or facebook or youtube 0:49:00 Obviously there are forces out there they do not want this information in the public spere, but Jocelyn believes there also people out there that know something is wrong - benzo perscriptions have increased 10 fold over the last decade - doctors are just substituting benzos for opiates - so big pharma's profits increased by 10 fold - since COVID, anxiety meds prescriptions have increased 34% 0:50:00 Alliance of Benzo Best Practices is a group of doctors who understand, and researchers who want to do research for the FDA to change recommendations, and to re-educate doctors on these drugs 0:51:00 The stuff pharma puts out, does not warn people about what these drugs can do   Connect with Jocelyn Pedersen:   People can pre-order Seeds of Hope: A Journey Through Medication and Madness Toward Meaning through moongladepress.com and when it's released June 1st on Amazon.com: https://t.co/267G0VaBiz?amp=1My channel is YouTube.com/c/BenzoBrainsSome other helpful resources are benzoreform.orgbenzoinfo.combenzo.org.uk/manualcouncilforsustainablehealing.org   Be a podcast patron Support Medical Error Interviews on Patreon by becoming a Patron for $2 / month for audio versions.  Premium Patrons get access to video versions of podcasts for $5 / month. Be my Guest I am always looking for guests to share their medical error experiences so we help bring awareness and make patients safer. If you are a survivor, a victim’s surviving family member, a health care worker, advocate, researcher or policy maker and you would like to share your experiences, please send me an email with a brief description:  RemediesPodcast@gmail.com  Need a Counsellor? Like me, many of my clients at Remedies Counseling have experienced the often devastating effects of medical error. If you need a counsellor for your experience with medical error, or living with a chronic illness(es), I offer online video counseling appointments. **For my health and life balance, I limit my number of counseling clients.**  Email me to learn more or book an appointment:  RemediesOnlineCounseling@gmail.com Scott Simpson:  Counsellor + Patient Advocate + (former) Triathlete I am a counsellor, patient advocate, and - before I became sick and disabled - a passionate triathlete. Work hard. Train hard. Rest hard. I have been living with HIV since 1998. I was the first person living with HIV to compete at the triathlon world championships. Thanks to research and access to medications, HIV is not a problem in my life. I have been living with ME (myalgic encephalomyelitis) since 2012, and thanks in part to medical error, it is a big problem in my life. Counseling / Research I first became aware of the ubiquitousness of medical error during a decade of community based research working with the HIV Prevention Lab at Ryerson University, where I co-authored two research papers on a counseling intervention for people living with HIV, here and here.  Patient participants would often report varying degrees of medical neglect, error and harms as part of their counseling sessions. Patient Advocacy I am co-founder of the ME patient advocacy non-profit Millions Missing Canada, and on the Executive Committee of the Interdisciplinary Canadian Collaborative Myalgic Encephalomyelitis Research Network. I am also a patient advisor for Health Quality Ontario’s Patient and Family Advisory Council, and member of Patients for Patient Safety Canada. Medical Error Interviews podcast and vidcast emerged to give voice to victims, witnesses and participants in this hidden epidemic so we can create change toward a safer health care system. My golden retriever Gladys is a constant source of love and joy. I hope to be well enough again one day to race triathlons again. Or even shovel the snow off the sidewalk.

“Sexual health for women doesn’t start with hormonal balance in their menopausal years, but well before, when they start taking hormonally-driven birth control. The mainstay of treatment for our patients, especially the younger ones is getting them off the pill. Cause that's often the primary issue in a lot of women.” – Dr. Joshua Gonzalez   In today’s episode, Dr. Shah continues his no holds barred conversation about the taboo topic of sexual health with Dr. Joshua Gonzalez. If you missed the first episode, these knowledgeable gentleman talked primarily about men’s sexual health. In this talk, we’re dedicating Dr. Gonzalez’s expertise to women’s sexual health.   Surprising findings from recent research has revealed that birth control pills are affecting hormonal balance in woman at younger and younger ages – and causing their sexual lives to become stilted unnecessarily. The pill can mess with your thyroid hormones, sex hormones, and even lower your sex drive.   For women entering menopause, there are a whole different set of factors to alleviate – but young or reaching their golden years – women face hormonal balancing challenges as the primary impetus behind their sexual vibrancy.   Dr. Gonzalez is a board-certified urologist and specialist in hormonal balance, and sense female sexual health from puberty to well after menopause has so much to do with hormonal balance – even through the use of certain hormonally based birth controls – it’s time to learn more about estrogen, testosterone, oxytocin, vasopressin, progesterone, cortisol, binding globulin, and more!   Uncover the mystery that reveals your most intimate and amazing experience with sex ever. It’s got a lot to do with physiology, not just your psychology. Dr. Gonzalez is a life-saver for any woman struggling with sexual performance or fertility. Stop Googling your sexual symptoms, and listen in to this engaging conversation to learn more.   Highlights: Understand why you need a physiological workup before you ever consider seeing a sex therapist or psychologist to address sexual issues. Learn why even after you stop taking birth control pills, they may still be causing elevated hormonal levels that can negatively impact your sex life. Learn why SHBG causes testosterone deficiency – and why you want testosterone in balanced amounts, even as a woman. Learn why too much testosterone (caused by birth control pills) can cause vaginal dryness, and a lowered sex drive. Discover why sleep, diet, and your stress levels are also impacting your sexual function. Figure out why hormone replacement therapy got a bad rap, and how it’s changed drastically. Realize that urinary tract health is closely tied to vaginal health and sexual comfort. Find out what might be causing your lubrication issues. Learn about your pelvic floor, and its muscular foundation for your sexual happiness. Understand why painful intercourse in the past may have made your brain develop a hypersensitivity to pleasurable sex now. Realize why drugs like Cymbalta may not be the best answer for your sexual dysfunction. Does your vagina or rectum need Botox? Get real answers about your sexual questions even if your gynecologist has appallingly told you to just have a few glasses of wine and relax to enjoy sex.   Next|Heath: Website: https://www.next-health.com/ Instagram: @next_health Facebook: https://www.facebook.com/nexthealth Google +: https://plus.google.com/+NexthealthWellness   Dr. Darshan Shah: Website: https://www.drshah.com/ Facebook: https://www.facebook.com/DarshanShahMD Making the Cut: https://www.drshah.com/making-the-cut.html   Dr. Gonzalez Website: https://joshuagonzalezmd.com/ YouTube: https://www.youtube.com/channel/UCVrC8tXLEfhTHxKDFdAO4gA Instagram: https://www.instagram.com/explore/locations/1020772788/joshua-gonzalez-md Twitter: https://twitter.com/SexMedLA Facebook: https://www.facebook.com/JoshuaGonzalezMD/

Neuropathy and Chronic Nerve Pain sufferers often have nowhere to turn to for help. Medications like Lyrica, Cymbalta, and GabaPentin work in a small number of cases. Then their effectiveness gradually starts to decrease Where do the people with diabetic nerve pain or chemo-induced nerve pain turn to? Surely opioids may help in the short term but bring a whole host of comorbidities with them. If you are looking for some hope and help with your neuropathy, the answer may just be Neuropathy@CoreHealth.Dr. Brian McKay has developed quite a following helping people with a unique type of peripheral neuropathy treatment. Chances are you know what neuropathy feels like if you need more information about the different types of neuropathy the inside pages of the web site go into detail. If you are looking for a neuropathy medication from Neuropathy@CoreHealth you are in the wrong place. Our peripheral neuropathy treatment is a very special program that is broken down into several components.Nutritional Neuropathy ProtocolPeople with neuropathy, be it from diabetes, chemotherapy or autoimmune causes have diminished capacity from a nutritional standpoint. Neuropathy@CoreHealth utilizes specific supplements to help affected nerves and blood vessels. These nutrients help stabilize the body internally. Dr. McKay believes that you can not treat peripheral neuropathy unless there is a strong nutritional component that we deliver. Most neuropathy sufferers are aware of the need for increased B-Vitamins. We do not stop there our recommended supplements include Magnesium as well as Nitric Oxide boosters to further enhance our results.Vascular Peripheral Neuropathy TreatmentWhen we enhance blood flow the tissue can respond faster. The typically prescribed neuropathy medications do not address blood flow. Neuropathy@CoreHealth addresses blood flow using state of the art Near-InfraRed light therapy. The totally painless application of near-infrared light allows for angiogenesis. If you were wondering angiogenesis is where new blood vessels are created. The greater the blood flow the more likely the person with peripheral neuropathy will receive benefits from neuropathy treatment.Cold Laser Neuropathy TherapyNeuropathy@CoreHealth uses Class IV Cold Laser to stimulate the cells of the body to become more efficient. It does so by firing up the mitochondria of the cell, this is where cells get their energy. So by enhancing the energy center we can give the body mor of what it needs but has a hard time producing- energy. Cold Laser is applied locally to the hands and feet of all neuropathy cases we treat. We feel it is an important step that ensures help for our neuropathy patients.PEMF Pulsed Electro Magnetic Field TherapyNeuropathy@CoreHealth has been using PEMF for several years. As far as we know we are the only neuropathy treatment centers doing so. We have it to be a valuable tool. PEMF therapy uses bursts of low-level electromagnetic radiation to heal damaged tissues and bone, to relieve injury-related pain, and even to stimulate organs.diabetesdiabetic foot painneuropathyperipheral neuropathychemotherapydiabetic nerve paindiabetic footnerve pain in footdiabetic foot pain at nightdiabetes and foot problems symptomsdiabetes aching legstype 2 diabetes foot problemspain in fingers and toes diabetesthrobbing feet diabetestoe cramps diabetesdiabetic neuropathyneuropathic paintingling in feetwhat is neuropathy

The most common medications recommended for neuropathy are anti-seizures and anti-convulsants medications. Lyrica is FDA authorized to treat diabetic neuropathy. There are possible negative effects to take into account, drowsiness, weight gain, dizziness, and queasiness. Anti-depressants are also authorized to deal with the pain associated with neuropathy. This would be Cymbalta which brings the threat of fatigue, drowsiness, and dizziness. So it would make good sense to question whether or not the remedy deserves the physical cost of dealing with neuropathy. Neuropathy can not be treated however can be helped.Here are some things you can start doing immediately to help your peripheral neuropathy. B-Vitamins are a great beginning point. Many Americans lack B-Vitamins. You can ask your doctor which type to take, there are a number of to select from. If you smoke, stop immediately. Smoking cigarettes actually makes it harder to get adequate blood supply to the muscles and nerves in your legs. The legs figure predominately in cases of neuropathy. Warm baths will not just unwind the muscles however also promotes blood circulation. Workout, obviously, is shown to relieve a few of the discomfort connected with peripheral neuropathy. You should really start to exercise under the assistance of a physiotherapist. Your doctor can recommend a physical therapist.If there is something to remove from this article is that you need to stay active. If you can no longer walk your pet dog because it injures to stroll it is important to restore that ability. Even if the pain is bad, work through the discomfort. Activities that bring you joy can help combat the psychological tiredness that may accompany the medications. Merely depending on medication is inadequate. You must advocate on your own and combat to keep doing what defines you as a person.

In 2004, before any drugs were FDA approved for treating fibromyalgia, several antidepressants had achieved some success for patients with fibromyalgia. In that year, duloxetine (Cymbalta) was also approved - for treating depression. But would it make a name for itself as the first FDA approved treatment for fibromyalgia? Today's article is available in full-text here: https://onlinelibrary.wiley.com/doi/epdf/10.1002/art.20485 Made with Auxbus.com See omnystudio.com/listener for privacy information.

Welcome to FibroSmart, MD, the podcast that pits science against fibromyalgia! In this episode, I'll discuss evidence-based medicine for fibromyalgia, delivered in a collaborative treatment model that respects the individual. It's real medicine, and real science. For a (yes, you guessed it) real disease. Here are the links from the show: PainScience article that discusses evidence based medicine and science based medicine. https://www.painscience.com/articles/ebm-vs-sbm.php The first study (I know about) looking at duloxetine (Cymbalta) and fibromyalgia is available in free full-text format here: https://onlinelibrary.wiley.com/doi/full/10.1002/art.20485 FibroSmart, MD webebpage: https://FibroSmartMD.com See omnystudio.com/listener for privacy information.

Have you experienced numbness that had started in your feet slowly worked its way up your legs? It may be barely noticeable at first. You may shrug this off as nothing serious since there is no pain to speak of in the beginning. What you don't notice is what can hurt you later on. The muscles in your legs receive information from the nerves outside the spine. These are called peripheral nerves. When these nerves are damaged, the muscles in your legs send faulty information to the brain. The brain then signals the muscles to compensate. This may not seem to be too bad but what happens when the pain starts to become crippling? What about when it starts to prevent sleep and requires medication?Initially, you are not concerned about the possibility of falls, which can be disastrous as we all aware of. Most cruelly, with or without pain, peripheral neuropathy robs people of the things they loved doing. What happens when people give up physical activities like playing tennis or bike riding? Left untreated neuropathy renders everyday simple activities such as walking the dog impossible. With the loss of balance, walking without support is risky, stepping over the cat can be deadly, and picking up the grandchildren becomes a thing of the past.Estimates of the number of Americans with peripheral neuropathy vary, with the National Institutes of Health putting it at 30 million while the Foundation for Peripheral Neuropathy puts it at 40 million Americans. The Foundation for Peripheral Neuropathy has established a research registry to compile data and biosamples on peripheral neuropathy patients, sets the average age of those with the disease at 63, though onset often goes unnoticed and undiagnosed for several years.The most common medications prescribed for neuropathy are anti-seizures and anti-convulsants medications. Lyrica is FDA approved to treat diabetic neuropathy. There are possible side effects to take into consideration, drowsiness, weight gain, dizziness, and nausea. Anti-depressants are also approved to treat the pain associated with neuropathy. This would be Cymbalta which carries the risk of fatigue, drowsiness, and dizziness. So it would make sense to question whether or not the cure is worth the physical cost of treating neuropathy. Neuropathy cannot be cured but can be helped.Here are some things you can start doing right away. B-Vitamins are a good starting point. Most Americans are deficient in B-Vitamins. You can ask your physician which type to take, there are several to choose from. If you smoke, stop immediately. Smoking really makes it more difficult to gain adequate blood supply to the muscles and nerves in your legs. The legs figure predominately in cases of neuropathy. Warm baths will not only relax the muscles but also stimulates blood flow. Exercise, of course, is indicated to alleviate some of the pain associated with peripheral neuropathy. You should really start to exercise under the guidance of a physical therapist. Your doctor can recommend a physical therapist.If there is one thing to take away from this article is that you need to stay active. If you can no longer walk your dog because it hurts to walk it is important to regain that ability. Even if the pain is bad, work through the pain. Activities that bring you joy can help combat the mental fatigue that may accompany the medications. Simply relying on medication is not enough. You must advocate for yourself and fight to keep doing what defines you as a person.alleviate diabetic foot painare compression socks good for diabetic foot painbest medicine for diabetic foot pain

SHR # 2455 :: The Pep Talk: Cibinetide (ARA 290) This Groundbreaking Peptide Can Treat Neuropathy, Neuralgia and Fibromyalgia - Dr. Elizabeth Yurth, MD - The National Institute of Health estimates over 20 million people suffer from peripheral neuropathy. They also acknowledge that this number may be highly under-represented since there a other forms of neuropathy that don't cause pain. Add to that only recently it was shown that Fibromyalgia has a neuropathy and small fiber nerve damage component so add to that another 12 million - almost all women. The most insidious type of nerve degradation that rarely gets reported due to lack of pain attacks the organs in the body. Remove the nerve impulses from the heart, liver, pancreas or brain and slowly your body begins to fail. Most neuropathies are treated with drugs like Cymbalta in an attempt to mitigate the pain. They often don't work and carry horrible unwanted effects. This peptide looks to be the first thing that addresses the problem by fixing and repairing the nerves as opposed to masking the symptoms.

SHR # 2455 :: The Pep Talk: Cibinetide (ARA 290) This Groundbreaking Peptide Can Treat Neuropathy, Neuralgia and Fibromyalgia - Dr. Elizabeth Yurth, MD - The National Institute of Health estimates over 20 million people suffer from peripheral neuropathy. They also acknowledge that this number may be highly under-represented since there a other forms of neuropathy that don’t cause pain. Add to that only recently it was shown that Fibromyalgia has a neuropathy and small fiber nerve damage component so add to that another 12 million - almost all women. The most insidious type of nerve degradation that rarely gets reported due to lack of pain attacks the organs in the body. Remove the nerve impulses from the heart, liver, pancreas or brain and slowly your body begins to fail. Most neuropathies are treated with drugs like Cymbalta in an attempt to mitigate the pain. They often don’t work and carry horrible unwanted effects. This peptide looks to be the first thing that addresses the problem by fixing and repairing the nerves as opposed to masking the symptoms.

EPISODE #327 Anti-Depressants and Mass Shootings Pt. 2 Richard welcomes an expert in serotonergic medications to talk about the possible violent side effects of anti-depressant medications. GUEST: Dr. Ann Blake Tracy is the director of the International Coalition for Drug Awareness. She has specialized for 22 years in adverse reactions to serotonergic medications (Antidepressants such as Prozac, Zoloft, Paxil, Luvox, Effexor, Celexa, Lexapro, Cymbalta, Pristiq, Serzone, Anafranil, etc. and the diet pills Fen-Phen, and Redux and the newer Atypical Anti-psychotic medications such as Zyprexa, Geodon, Abilify, Risperdal, Seroquel, etc.) and has testified before the FDA and congressional subcommittee members on Prozac. She has testified since 1992 as an expert witness in Prozac and other SSRI related court cases around the world. Her first book on the issue was published in 1991. During the last twenty years she has participated in innumerable radio, television, newspaper and magazine interviews on this subject. She is the author of Prozac: Panacea or Pandora?   PLEASE SUPPORT OUR SPONSORS!! C60EVO.COMThe Secret is out about this powerful anti-oxidant. The Purest C60 available is ESS60.  Buy Direct from the SourceUse the Code RS1SPEC for special discount. Ancient Life Oil Organic, Non GMO CBD Oil.  Big Relief in a Little Bottle! The Ferrari of CBD products. Strange Planet's Fullscript Dispensary - an online service offering hundreds of professional supplement brands, personal care items, essential oils, pet care products and much more. Nature Grade, Science Made!   Life Change and Formula 13 Teas  All Organic, No Caffeine, Non GMO!  More Energy!  Order now, use the code 'unlimited' and your first purchase ships for free.

EPISODE #325 Anti-Depressants and Mass Shootings Richard welcomes an expert in serotonergic medications to talk about the possible violent side effects of anti-depressant medications. GUEST: Dr. Ann Blake Tracy is the director of the International Coalition for Drug Awareness. She has specialized for 22 years in adverse reactions to serotonergic medications (Antidepressants such as Prozac, Zoloft, Paxil, Luvox, Effexor, Celexa, Lexapro, Cymbalta, Pristiq, Serzone, Anafranil, etc. and the diet pills Fen-Phen, and Redux and the newer Atypical Anti-psychotic medications such as Zyprexa, Geodon, Abilify, Risperdal, Seroquel, etc.) and has testified before the FDA and congressional subcommittee members on Prozac. She has testified since 1992 as an expert witness in Prozac and other SSRI related court cases around the world. Her first book on the issue was published in 1991. During the last twenty years she has participated in innumerable radio, television, newspaper and magazine interviews on this subject. She is the author of Prozac: Panacea or Pandora? WEBSITES:   PLEASE SUPPORT OUR SPONSORS!! Ancient Life Oil Organic, Non GMO CBD Oil.  Big Relief in a Little Bottle! The Ferrari of CBD products. C60EVO.COM The Secret is out about this powerful anti-oxidant. The Purest C60 available is ESS60.  Buy Direct from the SourceUse the Code RS1SPEC for special discount. Strange Planet's Fullscript Dispensary - an online service offering hundreds of professional supplement brands, personal care items, essential oils, pet care products and much more. Nature Grade, Science Made!   Life Change and Formula 13 Teas  All Organic, No Caffeine, Non GMO!  More Energy!  Order now, use the code 'unlimited' and your first purchase ships for free.

Grant and Heavey talk about depression which is a serious, ongoing problem that is growing around the country. It's increasing in propensity amongst millennials, more specifically, so it's very important to talk about issues like this. In fact, Grant has been going to therapy for a while. Today, he shares his experience with antidepressants in the hope of spreading awareness.

The Case:  Natalie is 40 but feels like she’s 80 most days She was experiencing fatigue, aches and pains, poor sleep, and depression. After several doctor visits she was diagnosed with fibromyalgia, given medication and told to expect things to get worse. An estimated 4 million Americans are diagnosed with fibromyalgia. While symptoms can be present much earlier, most diagnoses are between the age of 35 - 45. And, women are much more likely to suffer from this condition.   The Investigation This health mystery is a little different from most of my cases. Natalie already had a diagnosis and was already treating her condition. When she came to me, she hoped there was a better way. She didn’t want to accept that she would have to take medication for the rest of her life or that she should just get used to the idea of getting worse. She wanted to know if there was any hope of her feeling better despite her fibromyalgia diagnosis.  I knew we had to connect all the pieces of the puzzle to find the true underlying cause of her condition. Joining me on the show today to discuss Natalie’s case is fibromyalgia expert, Dr. Rodger Murphree. He is a board certified chiropractic physician, nutritional specialist, and author of 5 books including “Treating and Beating Fibromyalgia and Chronic Fatigue Syndrome.”   Conventional Fibromyalgia Diagnosis Unfortunately, a lot of doctors don’t recognize Fibromyalgia. They see this long list of symptoms and they label the patient as a hypochondriac or someone who is lazy, crazy or depressed. Often, patients will have to see many doctors and go through a battery of tests to eliminate all known conditions before they actually get a diagnosis of Fibromyalgia. This can take years since so many doctors don’t recognize the syndrome.   Doctors who understand Fibromyalgia (and who are willing to give a diagnosis) often don’t really know how to help the patients because there’s no prescription, no drug-based therapy that will solve all of the issues. As a result, most doctors will tell patients to treat the symptoms and ‘learn to live with it.’   What is Fibromyalgia? Fibromyalgia is a syndrome made up of a group of symptoms. This collection of symptoms often includes achy, sometimes disabling pain, fatigue, insomnia, restless leg syndrome, irritable bowel, low moods and brain fog. When a combination of these symptoms are present and there is no other medical explanation, it’s likely to be Fibromyalgia. There is a sort of Fibromyalgia spectrum so not all Fibromyalgia patients are going to have the same experience or combination of symptoms. Dr. Murphree says that true fibromyalgia involves central sensitivity pain syndrome where the pain threshold becomes very low. Essentially, pain is magnified. Other senses may also be heightened such as sensitivity to bright lights and loud noises. Stress can also become magnified.    Stress and Fibromyalgia Up to 70% of Fibromyalgia patients say that stress was a trigger for their symptoms. It’s no surprise because stress is a trigger for most inflammatory reactions, which is the driver of most illnesses. In Fibromyalgia, we see a loss of plasticity to stress, or an inability to rebound from stress. This places the patient into a chronic state of stress that often shows up as pain and an inability to fall asleep or stay asleep. The stress causes more and more symptoms which causes the patient more stress and it becomes a vicious cycle.    Diagnosing Fibromyalgia Dr. Murphree looks at sleep when considering a Fibromyalgia diagnosis. He says that almost all patients who he suspects of having Fibromyalgia have pain and sleep issues. Many of the other symptoms that are commonly associated with Fibromyalgia, like IBS, low mood, and brain fog stem from the lack of quality sleep over time.    Treating Fibromyalgia Naturally Dr. Murphree says that he encourages his patients to shift their mindset away from the idea that drugs are the answer. He’s seen many patients who discover, after years of medicating, that drugs don’t help Fibromyalgia. All they do is poorly mask the symptoms without actually fixing the issue and they leave you vulnerable to side effects. It may seem impossible, but he says the only hope for patients is to get healthy.    Sleep is Critical for Healing Fibromyalgia Getting sufficient restorative sleep is step one in Dr. Murphree’s strategy for treating Fibromyalgia. Regular restorative sleep can decrease the amount of inflammatory chemicals your body release. A lack of deep sleep causes the metabolism to slow down which causes lethargy, weight gain and heightened pain sensitivity. It also causes brain fog and a decreased ability to deal with stress. For patients struggling with sleep, Dr. Murphree suggests temporarily taking melatonin to restore their sleep cycle.    Serotonin for Fibromyalgia Many of us know it as the happy hormone. Having healthy serotonin levels is critical in treating fibromyalgia. Serotonin increases your pain threshold, it improves digestion, and it decreases anxiety. Conventional medicine recognizes the importance of serotonin for Fibromyalgia patients. Unfortunately, the typical conventional solution is to prescribe anti-depressant medication like Celexa, Paxil or Cymbalta. The problem with this approach is that these drugs don’t increase the production of serotonin (which is what is needed) they only serve to maintain serotonin levels, or hang on to the existing serotonin in the brain. It doesn’t help to fix the problem. The natural approach to encouraging serotonin release is with a healthy diet - specifically where you are getting enough of the amino acid, tryptophan. Tryptophan, when combined with certain B vitamins, magnesium and vitamin C turns into serotonin. Additionally, patients may supplement with  5 HydroxyTryptophan (5HTP) to further support serotonin production. However, deep, restorative sleep is still a critical part of this treatment plan. Dr. Murphree outlines his recommended protocol at the 18 minute mark of this podcast.    Does 5HTP Work for Fibromyalgia Dr. Murphree has been working with patients with Fibromyalgia for decades and this is the protocol he’s seen to be most effective. Some patients have concerns because they are on antidepressant medication (which is contraindicated). He’s worked with many of these patients and has seen successes. However a very small percentage do report feeling nauseated or having headaches. It’s important to work with someone experienced with Fibromyalgia (like Dr. Murphree) if this is a concern for you.    Natural Stress Reduction One of the biggest challenges that patients with Fibromyalgia face is reducing stress - often the trigger of the Fibromyalgia in the first place. Dr. Murphree has been working hard to find natural ways to support the adrenal glands (which are responsible for the body’s stress response). He recommends adrenal glandulars. However, he cautions people to make sure that they get the cortex only type because most adrenal glandulars have both cortex and adrenaline. Too much adrenaline can cause adrenal fatigue.    Final Step in Fibromyalgia Recovery In addition to sleep, adrenal and serotonin support, the final step patients need to take is adjusting their lifestyle. A healthy diet is key as is regular exercise. Creating a mindfulness practice (like intentional breath work, meditation or journaling) is also important in resetting and managing the body’s stress response.    Cannabis for Fibromyalgia? The endocannabinoid system in an inborn system that regulates many different bodily systems. It affects body temperature regulation, sleep/wake cycle, digestion, certain hormonal systems, and pain thresholds. Taking CBD alters how the endocannabinoid system functions. Hemp oil, which contains CBD, has less than .03% THC so it provides the benefits of CBD without the ‘high’ that is associated with cannabis. CBD can repair a rundown endocannabinoid system resulting (for some) in an increased pain threshold while also correcting the circadian rhythm so that they can sleep better. However, not all hemp oil or CBD is created equal. Like many other plant crops, there is a vast difference between commercially grown and organically grown varieties.    Mystery Solved For Natalie, solving the mystery of her fibromyalgia started where most start - with her sleep. We supplemented her sleep with 5HTP and L-Theanine. She also adopted new sleep hygiene habits that put the priority on her winding down and relaxing before bed as well as protecting her natural melatonin production.  Once she was getting more restorative sleep each night, we began supporting her adrenals. Tests revealed her cortisol levels were low so she began with a supplement called Adren All from orthomolecular labs. We also introduced some stress reduction techniques to her daily routine.  To help her with her pain, Natalie was taking a CBD oil but it wasn’t as clean or as effective as it could be. She switched to an organic, higher quality CBD oil for her fibromyalgia symptoms.  The final step in helping her live comfortably with Fibromyalgia was to adjust her nutrition. She removed gluten and processed sugar from her diet and started eating clean, whole foods. She also shifted to drinking high quality water.   Happy Ending Just 4 weeks after we started working on this, Natalie was feeling so much better. She was sleeping better, she got her energy back and her pain had gone down by about 50%. The symptoms of Fibromyalgia were no longer something she would have to suffer with forever. Now, it was something she felt she could really live well with.    Eliminating Health Mysteries For Natalie’s case, we couldn’t cure her Fibromyalgia but we were able to find some of the root causes and give her the tools she needs to diminish the symptoms and feel so much better. Could these solutions help you or someone in your life with Fibromyalgia? Please share and let them know there is hope.    Resources Mentioned Thanks to my guest Dr. Rodger Murphree. You can connect with him through his website, on Facebook or Instagram. You can also find his book, Treating and Beating Fibromyalgia and Chronic Fatigue Syndrome on Amazon.   Suggested products 5HTP Synergy   L Theanine  Colorado Hemp Oil  Adren All  Livton Complex  Aqua Tru Water Filter Thanks for Listening If you like what you heard, please rate and review this podcast. Every piece of feedback not only helps me create better shows, it helps more people find this important information. Never miss an episode - Subscribe NOW to Health Mysteries Solved with host, Inna Topiler on Apple Podcasts, Spotify, Stitcher or Google Podcasts. Find out more at http://healthmysteriessolved.com   PLEASE NOTE All information, content, and material on this podcast is for informational purposes only and is not intended to serve as a substitute for the consultation, diagnosis, and/or medical treatment of a qualified physician or healthcare provider. Some of the links provided are affiliate links. This means we may make a very small amount of money should you choose to buy after clicking on them. This will in no way affect the price the product but it helps us a tiny bit in covering our expenses.

Antidepressiva können bereits in niedriger Dosierung gegen chronische Schmerzen helfen. Nach langer Bedenkzeit haben sich Jürgen und Lisa vor einigen Wochen dazu durchgerungen, die Medikamente auszuprobieren. Die Vorurteile und Skepsis sind groß: Verändern sie die Persönlichkeit? Machen sie dick? Was passiert da überhaupt im Körper? In dieser Folge berichten sie über ihre Erfahrungen mit den Antidepressiva Duloxetin und Amitriptylin. Als medizinischen Rat haben sich die beiden Dr. Falk Stirkat aus dem Podcast "DocPod"dazugeholt.

On this second episode of Akathisia Stories, we hear from Gail Regenbogen. In late 2010 Gail's husband, Howard, went on the antidepressant Cymbalta; in a short period of time he changed from the "very outgoing, happy" man Gail had known him to be through 30 years of marriage, to someone who was "real quiet and withdrawn." "This was three weeks into the course of the Cymbalta,” she recounts. “And that night my daughter called me up and she said, ‘We were all driving home and we were talking about dad tonight and I think something’s not right.’ And I said, ‘Well, I’ve noticed a change in his personality, as well.’ And my kids were concerned, and I sort of just kind of let it be because I really wasn’t educated on any of the side effects of any of these drugs. You know, all I knew is that these drugs work and they help people."

Medications Do Not Eliminate Pain Completely There are different pain medications out on the market. Pain medications are drugs used to relieve discomfort related to an illness, an injury or surgery and it is a complex process. Kathe and Les are back in this episode to talk about the article, Real Pain Relief, Now! There are different pain medications that provide relief by acting through a variety of mechanisms. When you are taking any kind of medication, you should start with the lowest dose possible. This is to alleviate your pain and not jump into a large dose. If you start with Ibuprofen for instance, which is usually 200mg per pill. The doctor will prescribe 800mg but you should start with the 200mg, if the 200mg does it, that’s what you should live with. A section of the article starts out by saying, “The goal of pills, patches, and creams is to take the pain down a couple of notches, not eliminate it completely.” This is to allow the person to exercise, work and socialize. Because, when you can take the pain down then you can do the movement which we talked about in the last episode. The typical doctor is going to just prescribe pain medications because the typical doctor is not necessarily trained on chronic pain. Just like we’ve said on the first episode, there’s 1 doctor in every 28,500 people that’s trained in chronic pain. And chronic pain is not helped by these short term drugs that are being tried. That's the downside when taking these different pain medications. Different Pain Medications that Relieve Pain Supplements. There are different pain medications that are prescribed and there are some that are necessarily not prescribed but can be helpful. Which falls under the category of supplements. Marijuana may relieve certain types of pain. The drug industry is not funding trials on supplements because they want to sell their drugs. Supplements like fish oil help reduce inflammation type pain and pain that is neurological. Another one is vitamin B and D. If you have deficiencies in these vitamins certain types of pain are going to be worse. Over-the-Counter Drugs. One of the other things that I found interesting that drugs like Ibuprofen and Aleve reduce swelling whereas Acetaminophen (Tylenol) makes you think that you’re not feeling pain. For Les’ personal experience, Ibuprofen works better than Acetaminophen for most of his pain. For headache pain though, Acetaminophen works better for Les than Ibuprofen. Acetaminophen and Ibuprofen are good for muscle and joint pain but they don’t seem to be very effective against nerve pain. A combination of Acetaminophen and Ibuprofen has had an effect very similar to opioids but you need to talk to your doctor before doing these combinations. Topical Creams. Topical creams like Tiger balm don’t necessarily make the pain go away as much as they make your body react to the burning/cold sensation, taking away from the other pain. There are these compounds called salicylates that produce the feeling of heat or cold to keep the nerves busy transmitting those sensations of pain instead of pain. Prescribed Drugs Antidepressants. There are different pain medications that need a prescription. Some doctors prescribe antidepressants for pain, which seems to be dangerous. There’s only one of that drug that has any connection with pain and that is duloxetine (Cymbalta). But it has a side effect of weight gain, constipation, and suicidal thoughts. Small doses can help with fibromyalgia, headache prevention, and pain due to nerve damage. Anticonvulsants. Anticonvulsants are dealing with the nervous system. If you have nerve pain it would have some effect but it doesn’t help if you have back pai...

'Selena, No! What are you doing!? NO! Don't do it! AHHHHHHHHH!''Tasha? Tasha?! Where ARE you???'Medication withdrawal can bring about some nasty symptoms - especially when no one warned you that they are as nightmarish as they can be. Listen in as we discuss our thoughts on medication withdrawl.

“The PIT ’’......My Story Welcome to the podcast Fibromyalgia Real Solutions with Amanda Love. You are listening to episode 2. By the way, you can listen to this podcast wherever you are in the world and at any time that you wish. I always include show notes for those with “ brain fog” so you don’t have to take notes. If you missed my previous episode on what to expect from my podcast you may want to listen to it before this one. I do believe that there is a lot of information both good and bad out there about fibromyalgia. As an educator who specializes in this area, I think it is my job to point out to you that the good information can be organized in a fashion that will guide you to take some action steps that will start you on the path to recovery. My name is Amanda Elise Love and I was diagnosed with fibromyalgia 9 years ago which influenced my decision to enter the field of nutrition and now I am a Registered Holistic Nutritionist who works with those who are suffering from fibromyalgia. The Long Slide into the Pit Throughout my infancy to the age of 20 I was very ill. For 8 to 10 days at a time, my temperature would elevate to over 104 degrees. I was toxic and the pediatricians and other medical professionals did not know why. I would recover only to be struck down again every 4 to 6 weeks later. My daily struggle to overcome this mysterious illness was beyond comprehension. I was distraught and my family was distraught as I fought this mysterious illness over and over again. Then, it happened !!!! I fell into “The Pit “. Now a new round of specialists became involved. These included a Rheumatologist, Physical therapist, Chiropractor, ENT, wellness facilities, pain center, and acupuncturist. After all of these consultations, I had no answers and I felt no better. Eventually, the Rheumatologist decided that I had fibromyalgia. The only recommendations she made included taking Cymbalta and going to physical therapy. The Cymbalta made me feel so terrible and nauseated and did nothing for the pain. I had weeks of physical therapy and deep muscle injections at the pain center which were excruciating and neither of these helped. A year went by and I’m still looking for answers that would help my extreme pain and fatigue. “I was definitely in the pit!” The pit of frustration, pain, exhaustion, discouragement, anxiety, depression and so on. It was dark and lonely in this pit but I had some renewed hope one day when I found a broken ladder in the pit. The rungs in the ladder were all there too so I tried to match them to the rails but the ends of the rungs where all different, some were round, some square, some triangular. I tried so hard to fit the rungs but I couldn’t. I started calling out hoping that someone would hear my cries. Someone did. She said, “ I could give you some pain medication that would help you get out of this pit.” Someone also said “I have some massage oil that would help relieve your pain. It is the latest thing.” Another person said, “you have to try the immune-boosting diet that will give you more strength.” And so it went and so it went. For the rest of the show, notes click on this website-http://amandaeliselove.com/the-pit-my-story-show-notes/Top 10 Fibromyalgia Podcasts You Must Follow in 2020- https://blog.feedspot.com/fibromyalgia_podcasts/

Alison Yates is a multi-hyphenate creative living in Los Angeles. A comedienne and actor, producer, writer, photographer, social media manager, website designer, and skincare consultant (phew!), she performs sketch and comedy regularly with Second City and the Groundlings, and has a production company called The People Zoo. She’s been featured on several TV shows, including Jane the Virgin and Mom. She’s lived with migraines since she was 6 years old, and depression and anxiety since she was 15; she very clearly sees the direct link between her migraines and her mental health symptoms. Listen in as Alison shares…  - when she had her first migraine (aged 6), and that she sees a genetic link in her family  - that she also has digestive issues associated with her migraines and emotional wellbeing, and as such is always aware of the location of the nearest bathroom  - that her digestive issues are currently undiagnosed (have been diagnosed as IBS in the past), but she manages her symptoms with dietary restrictions  - how her migraines come on and manifest  - treatments she’s tried to manage her migraine symptoms: pharmaceuticals (including Imitrex, Cymbalta, and Aimovig), marijuana and CBD, sleep, chiropractic, massage, physical therapy, acupuncture, Botox, daith piercing, yoga, meditation, and dietary changes  - that many migraine medications also have an antidepressant effect  - that women are more prone to migraines than men  - that her entire life is designed around her migraines  - that there is a cause and effect for every migraine, and her migraines are easily triggered by bright lights and spinal re-alignment (especially Alexander Technique and chiropractic)  - that she sees a direct link between her migraines and depression/anxiety  - that she overdosed on her migraine meds when she was 18  - that she struggled to access Aimovig (monthly migraine medication) for 5 months, and finally got it  - that she’s gone through at least 15 medical practitioners and medical practices in an effort to control her symptoms  - that she experiences numbness after her aura – very similarly to stroke patients; sometimes she can’t distinguish whether she’s having a stroke or a migraine  - that she’s at a higher risk for stroke because of her migraines  - that she has learned to be her own health advocate  - that she makes occasional visits to the ER for morphine if her pain is off the charts  - that her migraines have wrecked her financial life and spiraled her into debt – between specialists, insurance costs, and surgeries  - the guilt she feels when canceling plans when she has a migraine coming on, and the gender divide on guilt and responsibility toward others  - that remote work has been essential to her earning capacity because she can’t work 9-5  - that she’s created her own community of migraine survivors through social media  - that, while social media can be helpful in terms of building community, it can also be incredibly alienating  - that it’s much easier to talk publicly about her migraines than it is for her to address her anxiety and depression  - that migraines have given her some agoraphobia and social anxiety  - that she was told early on by friends that her “feelings were too big”, so she retreated into herself and her comedy is drawn from an accordingly deadpan style  - that acting has been a productive outlet for her depression  - the prevalence of mental illness in the entertainment industry  - that trying to “be better” is exasperating 

When you’re using Cymbalta, a nerve pain medication, and also using CBD Oil, there are some considerations to take into account. Can CBD Oil be taken with Cymbalta? It’s not recommended at this time, as studies are discovering that there are potential harmful effects. When CBD and Cymbalta are mixed together, there have been some known […] The post Can CBD Oil be Used With Cymbalta? appeared first on CBD Oil Kansas City.

Kristen discusses going off Cymbalta, Sarah shares about posting about herself in a bra, and we discuss our rules around what we post (and won’t post) on social media. This week we talked about: Athleta Primaloft Tights Nude Slim Fit Layering Tees Schitt’s Creek Capri Blue Alpine Juniper Candle   Podcast (selfie): Play in new window | Download Subscribe: Apple Podcasts | Android | Google Podcasts | Stitcher | Spotify | RSS

Richard speaks with a court expert witness about the frightening connection between mass shootings and anti-depressant drugs.  In virtually all mass-shootings, the shooters were taking some type of anti-depressant or anti-psychotic medication. GUEST: Ann Blake-Tracy is the director of the International Coalition for Drug Awareness. She has specialized for 22 years in adverse reactions to serotonergic medications (Antidepressants such as Prozac, Zoloft, Paxil, Luvox, Effexor, Celexa, Lexapro, Cymbalta, Pristiq, Serzone, Anafranil, etc. and the diet pills Fen-Phen, and Redux and the newer Atypical Anti-psychotic medications such as Zyprexa, Geodon, Abilify, Risperdal, Seroquel, etc.) and has testified before the FDA and congressional subcommittee members on Prozac. Her first book on the issue, Prozac: Panacea or Pandora? was published in 1991

On Episode #9, Psychiatric medication may work for some people but many people have had different experiences or aren't willing to take the chance, given some of the devastating and debilitating side effects that may occur from taking commonly prescribed pharmaceutical medications like Lyrica, Seroquel, Cymbalta, Vyvanse, Latuda, Invega and Pristiq. Listen in as we talk with holistic health practitioner, Judy Meyer, about alternative mental health treatment that involves holistic options which are often safer and more personalized to an individual's needs. Show note links: Check out the 2016 list of top selling psychiatric medications on Statista.com (Lyrica was on the list with over $4 billion dollars in revenue) Connect with Judy on Instagram (Holistic_Depression_Coach) and/or Twitter (@altmentalhealth). You can also visit her websites at: www.AlternativeMentalHealthRevolution.com, www.HolisticDepressionCoach.com To visit the Alternative Mental Health Revolution blog, click here To read "healing stories" from people who have used holistic options as an alternative to psychiatric medications, visit AlternativeMentalHealthRevolution.com or click here Also mentioned in this episode... To access practitioners/providers who are supportive of alternative mental health options: www.MadInAmerica.com, www.AlternativeMentalHealth.com Map your 23andMe or AncestryDNA results to NutraHacker.com for "cutting edge nutrition" recommendations customized to your unique genetic profile. Curious to know more about tardive dyskinesia (mentioned in the first few minutes of the show)?  Check out this on Wikipedia.

I talk about common Cymbalta questions. I share my experience taking Cymbalta.

Santa Fe shooting: Texas governor confirms 10 people dead and 10 woundedGovernor Greg Abbott confirms the number of fatalities in a shooting at a high school about an hour south-east of Houston.https://www.theguardian.com/us-news/2018/may/18/texas-school-shooting-santa-fe-highAntidepressants Nightmareshttps://ssristories.orghttps://twitter.com/alexexumwww.alexexum.com

Santa Fe shooting: Texas governor confirms 10 people dead and 10 woundedGovernor Greg Abbott confirms the number of fatalities in a shooting at a high school about an hour south-east of Houston.https://www.theguardian.com/us-news/2018/may/18/texas-school-shooting-santa-fe-highAntidepressants Nightmareshttps://ssristories.orghttps://twitter.com/alexexumwww.alexexum.com

Welcome back to our weekend Cabral HouseCall shows! This is where we answer our community's wellness, weight loss, and anti-aging questions to help people get back on track!  Check out today's questions: Ruben: Hello Dr. Cabral, First of all THANK YOU for putting in the time to put out the podcast on a regular basis. I wasn't sure what address to reach out with my question, so I figured I would start with this one. The question is actually for my wife. She had a annual exam yesterday and the Cholesterol test came back high. The doctor prescribed her a low dose Statin. My wife has been really sad since then because she really watches what she eats and is active. here is a brief overview: Height: 5'8 Weight: 134 lbs Age: 38 - Does not eat beef/pork - Eats chicken ( once a week) - eats fish ( once a week) - drinks a green drink 98% of the time, daily ( spinach, banana, apple, ginger, tumeric, spirulina, water) - when she doesn't pull her back ( she has few back issues), she works out about 4 times a week. - workouts consist: 10 minutes cardio fast pace, 20-30 minutes strength and conditioning. - Prior to the blood test she hasn't really worked out for about 2 weeks here are the numbers ( fasted test) Chol: 280 Trigly: 173 HDL: 51 Chol/HDL rate: 5.49 LDL: 194 Non HDL Chol : 229 Rest of the numbers look good. She has a history of high cholesterol even though she doesn't eat bad at all 2012 : Chol 169 | Tri 62 | HDL 40 | Ratio: 4.23 | LDL 117 2015: Chol 246 | Tri 139 | HDL 46 | Ratio: 5.35 | LDL 172 2017: Chol 226 | Tri 186 | HDL 47 | Ratio: 4.81 | LDL 142 2018: Chol 280 | Tri 173 | HDL 51 | Ratio: 5.49 | LDL 194 She does not want to start taking a statin but she really feels defeated, so I am reaching out to see if there are any other tests that she could do to make sure there aren't other things that are actually causing the high cholesterol. Also, if she can do any of your protocols or any of the daily support products. Any info that could give us some hope or something to try in the near future would be really really appreciated! Kind Regards, Ruben Breanna: Hi Dr. Cabral. Thank you so much for providing us with such amazing content, and inspiring many to live happier, healthier and happier lifestyles. I listen to your podcast daily and have providing me with the knowledge I've always wanted to know growing up. I have a little story for you. For as long as I can remember I would be in excruciating pain 24/7, especially in the morning. I was diagnosed with lactose intolerance as a baby, but it wasn't until I was 11 years old that the doctors diagnosed me with Celiac Disease... then depression, then anxiety, then acid reflux, then anemia... my symptoms never went away, my intestines never fully recuperated and I was taking 5 different pills daily at 12 years old, despite eliminating gluten. I stopped taking all medication a year ago because I was fed up and I am now 18. Through your podcast I now realize why all these extra symptoms occurred and how they were going against me.. the health system failed me. My intestines still aren't fully recuperated but this isn't part of my question. I just believe my health background may play a part in my current situation. I was always super active growing up as I was a competitive dancer. A year ago I decided to start going to the gym and got approached by a coach who offered her services to help prepare me for a bodybuilding competition. I did my first competition in april and won 2nd place. That diet wasn't bad and didn't have to do too much cardio as I was only 17 and she didn't want anything bad to happen. 3 months later I started prepping for my second show, at 18 years old. My "diet" lasted 12 weeks. She started me off at 1800 calories, lowered weekly and by the end I struggled to loose weight. For the last 4 weeks I was doing 2 hours of cardio + 1 hour weight training, and my diet composed of 5 chicken breasts and 2 tbsp ground flaxseed (+ 1/4 cup oats ONCE a week on leg day, and cut out those carbs 2 weeks out). How did I survive? Barely. I realize that this is extremely unhealthy, but I was too far in to give up. I had 0 days off the gym in 4 months. Also, I was extremely constipated. There was a period where I went 4 weeks only pooping 3 times and had to use diuretics each time to force myself to go!!! I started taking probiotics as another coach had told me this helped her use the bathroom, and it did for a while. My body toxicity was so high. She also advised me to use "estro control" to help get rid of that toxicity and loose my last pounds on my legs. I won first place by the way :). But here is my question.. what exactly did I do to my body? And what could I do differently next time? From listening to your podcasts, (especially your low carb diet ones), I realize I lowered my metabolism dramatically, lowered my thyroid, increased cortisol, burned a lot of muscle and increases levels of disease from purely eating chicken. To put in perspective, I'm 18, 5ft, mesomorph body type, was 95 pounds before going to the gym, gained a lot of muscle and started my diet at 112 lbs but cut down to 98 lbs for my competition. To reverse diet, she advised me to eat 200g carbs, 100g protein and 45g fat, and 0 cardio.I had very minimal "cheats", meaning I only eat whole clean foods such as sweet potato, rice, berries, gluten free oats, veggies, protein powder, eggs, chicken, extra lean ground turkey, rarely red meat, nuts, peanut butter and coconut oil (literally all I eat). Following this diet I am 5 weeks post show and 120 lbs!!! I went from being 10% body fat to having the most fat on my body I've ever had. So what do I do now? Do I just follow this new diet and wait for my metabolism to reset? I know that lowering my calories and doing cardio is only going to hurt me more in the long run (metabolism, thyroid, cortisol)... so I'm just confused and extremely unhappy. On top of that, I haven't gotten my period in months (and no I'm not pregnant). I now go to the gym 5 times a week to weight train and I take multivitamins, omega 3, potassium, digestive enzymes and probiotic5, but no more estro control... should I still be taking these supplements? I have recently started implementing your morning routine (water, yoga, smoothie) and definitely feeling better, but not looking better. Can you help me? I'm sooooo lost. And I know you are the best of the best, and the only person I would trust answering this properly, as you always look at all perspectives. Amanda: Hi Dr. Cabral, I have been listening to your show for over a year and absolutely love it. I receive more knowledge from you to help my clients than most other sources. My question is about a current private client I am working with. She is about 65, has had 2 heart attacks in the last 8 years (the last one about 2 years ago) and she is on about 12 different medicines (metformin, wellbutrin, Spironolactone, Zetia, *Metoprolol ER, *Crestor, *Aspirin, Cymbalta, Levothyroxine, Plavix, Avapro) progesterona along with 2 topical hormones estrogen and testosterone. My question is, what would be your order of operations for this client. She is open and ready to change her diet and lifestyle and ideally, one day she would love to not be taking any medications or the least amount possible. I've got her on your daily support shake and doing berry smoothies daily. We are working on increasing her stomach acid and next I would like to help her get rid of heavy metals (is there something you recommend for this that won't interfere with her medications?) She is on so many medications and I can see that they are crossing to cause many of her symptoms, I also want to be sure to take things really slow and respect her doctor decisions (although she has tried to come off medications many times and they almost always resist her requests). Any advice would be great, thanks for all that you do   Judy: Hi Dr. Cabral! I just finished your podcast (713) on body types and Inhave a follow up question. I am currently on week 2 of your detox and I have suffered for over a decade with adrenal fatigue and hypothyroidism. Therefore, I have metabolism issues that I didn’t always have at a young age. When determining my body type, should I consider my current state or when I aas a kid with no health issues? Judy: Hi Dr. Cabral, In your podcasts, you mentioned the importance of a cheat meal once a week for grehlin and leptin levels. I have a hard time resisting cravings once I cheat. I am on week 2 of your detox and no linger crave all the bad foods. I worry I will go downhill again once I allow myself the bad foods. What do you recommend I do to prevent a relapse? Are the better cheat foods to stick with that still address grehlin and leptin and avoid a relapse? What about portion sizes for cheat meals?   Thank you for tuning into today's Cabral HouseCall and be sure to check back tomorrow where we answer more of our community’s questions! - - - Show Notes & Resources: http://StephenCabral.com/771 - - - Get Your Question Answered: http://StephenCabral.com/askcabral  

If you have been prescribed Zoloft (sertraline), you may be wondering about Zoloft life insurance eligibility. Getting approved for life insurance with a Zoloft prescription history is possible… if you have the right insurance agent and insurance company! There are many medications used to treat depression. Celexa, Cymbalta, Lexapro, Paxil, Wellbutrin, and Zoloft are some.. More The post Zoloft Life Insurance Eligibility appeared first on Life-Wealth-Win.

For some of us with an anxiety condition it is a short detour, it gets resolved. For others we’ve been on this dang road a long time; some since childhood, our teens or early twenties. The good news is that there is treatment and you might have to make some lifestyle changes but you can feel better.   Resources Mentioned:    MedLine Plus information page on Duloxetine/Cymbalta. Consumer version of the Merck Manual Drug Search page Healthy Place (America's Mental Health Channel) page on Duloxetine. Scott Stossel's book, My Age of Anxiety you can read an excerpt or listen to a portion of the audio recording on Amazon. Elizabeth Vargas's book Between Breaths: A Memoir of Panic and Addiction also on Amazon   Disclaimer:  Links to other sites are provided for information purposes only and do not constitute endorsements. Always seek the advice of a qualified health provider with questions you may have regarding a medical or mental health disorder. This podcast is intended for informational and educational purposes only. Nothing in this program is intended to be a substitute for professional psychological, psychiatric or medical advice, diagnosis, or treatment

[intro music] Host – Dan Keller Hello, and welcome to Episode Eight-two of Multiple Sclerosis Discovery, the podcast of the MS Discovery Forum. I’m Dan Keller. Depression affects as many as 50 percent of people with MS during their lifetimes. But according to Dr. Adam Kaplin, a psychiatrist in the Johns Hopkins MS Center in Baltimore, it is treatable to a large extent, and with good results. Dr. Kaplin studies the immune basis of depression and cognitive impairment, specifically in MS and central nervous system-related autoimmune diseases. We met in Baltimore. Interviewer – Dan Keller Let’s talk about depression in multiple sclerosis. Is it a reaction to someone having a chronic disease, or is there something more going on because of the disease? Interviewee – Adam Kaplin It’s a great question, and what I will tell you is one of my patients says to me that you’re either stressed, or you’re dead. We all have stress going on, and it’s always possible to look at something in our life and say, ah, that’s what caused the trouble. But we know now, in multiple sclerosis, the depression is due primarily and dramatically significantly to the inflammation going on in the brain that causes all of the symptoms that you see in MS, such as cognitive impairment, or weakness/numbness/tingling, autonomic nervous system dysfunction; all of those are effects of the MS on the CNS. And in the case of depression, it is similar. It’s not a character flaw. It’s not a personal weakness. And just to, you know, clarify, one of the best pieces of evidence we have for that is, number 1, that people who are depressed with MS, it does not correlate with their EDSS scores. It doesn’t correlate with their level of disabilities. So if it was you know, gee, it’s just a matter of stress, then those people who are in wheel chairs or on ventilators should be depressed, and those people who are upright and walking around shouldn’t. But in fact, I think the key element is that this is one of the, as they often say, silent symptoms of MS. It occurs to 50% of patients across their lifetime. And it is important you know for people to understand that this is not something that people aren’t rising to the occasion, or those kinds of things. MSDF Is depression accompanying MS more prevalent than in the general population, and how serious is it? Dr. Kaplin You know people often ask why, as a neuropsychiatrist, why study MS? And I say, you know, why did Willie Sutton rob banks? That’s where the money is. MS has the highest rate of clinical depression of any medical neurological or surgical disease. Again, 50% of people, following the diagnosis of MS, will have a clinical depression. We can talk about what that is. And it turns out that that’s in any clinic you go into – neurology clinic – that’s one in four patients. If you go out to the waiting room, one in four patients will be suffering from a clinical depression. MSDF How serious a problem is it? What aspects of life does it affect? Does it affect everything, and how serious is it? Dr. Kaplin I think what is often misunderstood about the depression in MS is, I would argue, that it has the highest morbidity and mortality of any of the symptoms of MS, in the sense that it is the third leading cause of death in the largest study that looked at, across the lifespan, what causes death in people with MS, [found] a study out of Canada, where it’s more prevalent because of the higher elevation and the lower vitamin D levels, probably. And it is absolutely the case that seven-and-a-half times the rate – the suicide rate in MS – to the general population. And in fact, in the studies that were done, 30% of people with multiple sclerosis will have thoughts of suicide at some point during their life. Ten percent – fully 10% will attempt suicide. And that lethality is profound. But if it doesn’t kill you, it is important to understand that it has significant, significant morbidity associated with it. Just to begin with, the number one correlate of quality of life of patients—more important than their pain, or more important than their cognitive impairment, or weakness, or other symptoms—the number one correlate of the quality of life of the patient is their depression or whether they are depressed or not. And it’s similarly the number one quality of life of the care givers—not whether they have to push them around in a wheelchair, it is whether their loved one is suffering from a clinical depression. So it has significant morbidity and mortality associated with it. MSDF Are there aspects of serious depression in MS that are very characteristic? Any different from other severe depression? Or can it be recognized in the same way with the same diagnostic criteria? Dr. Kaplin There actually are some specifics to MS, although that hasn’t been well-published. I can be clear about things that are well-supported by the literature, and then those that are my clinical experiences. What I can tell you is that the way we diagnose depression in MS is the same way we diagnose depression in people without MS, which is you have to have 5 of 9 symptoms greater than two weeks, one of which must be either decreased mood or decreased interest. And we remember it by SIG-EM-CAPS, the nine symptoms. Trouble with sleep, where people are often having early morning awakenings or hypersomnia where they just sleep all day. Loss of interest, people’s get up and go has gotten up and gone. Feelings of guilt or worthlessness – and that’s a big problem, because patients who are depressed as a result of that often won’t seek help. You have to ask about it. They won’t volunteer it. And loss of energy or fatigue; low mood – that’s the sadness part; concentration problem; appetite changes, either increased or decreased weight; and psychomotor retardation, they’re not their normal bubbly self; and thoughts of death or suicide. With MS, what I will tell you, I find that patients with MS often, rather than sadness, have very frequently irritability. That tends to be more common. And sleep is usually decreased, not increased, so I see very frequently increased early morning awakening and those kinds of things. One pearl, though, to keep in mind is – or two pearls – if you’re trying to make the diagnosis of depression in somebody with MS, the first thing to do, because there are overlapped symptoms like fatigue, like concentration problems between depression and MS, so there is frequently, in up to 80% of people, will have diurnal variations in their moods; so usually worst in the morning and better at night. Sometimes it’s reversed, but you know that person has the same life circumstance, the same disease circumstance in the evening that they did in the morning, but their mood has changed dramatically, often, with MS with these cyclical changes. And that’s a good indication that it’s not demoralization; it’s depression. The other thing is ask the loved one. Get an outside informant, because nobody gets the brunt of it quite like the family. And they know that person, and if the family member says the one thing I hear so often, this is not the person I married, then you’re pretty much on the right track if you’re thinking about depression. MSDF How amenable to treatment is depression in MS? Dr. Kaplin I think that that is probably one of the key aspects is to understand that it is very treatable. So my expectation when patients come to me and I diagnose them with depression is that I will get them a hundred percent well with respect to those SIG-EM-CAPS symptoms, back to their baseline. And it’s very hard to get patients a hundred percent well from their gait problems; a hundred percent well from their cognitive problems. And, again, what I tell people is, look, I can’t tell you whether your cognitive impairment is due to the depression or due to the MS, or maybe it’s 10% depression/90% MS or 90% depression/10% MS. But I can promise you this: treating the depression, the depression is much more amenable to treatment. We don’t have good treatments for cognitive impairment in MS to reverse the cognitive impairment, but boy, we can reverse it if it’s a symptom of depression. What’s really exciting now is that we are now understanding more and more that many of the treatments you use for depression end up being good nerve tonics. So, there was a double-blind placebo-controlled study of fluoxetine demonstrating that, in patients who weren’t depressed with MS, they had fewer gadolinium-enhancing lesions over 24 weeks. And then there was the FLAME study in a related kind of way looking at fluoxetine as a way of significantly enhancing the recovery of hemiplegic stroke patients. So it turns out that I wasn’t so misguided in thinking that studying the immune basis of depression would be important, because as it turns out, our treatments actually do have an effect on the nervous system and the immune system for general types of depression as well. MSDF That sort of covers the SSRI class. What about tricyclic antidepressants? What about SNRIs? Do those fit in? Dr. Kaplin Yes, so absolutely. So the topic of how to choose and select the right treatment for patients with MS is … we could spend an hour and just sort of get only the highlights done there. But generally there’re sort of two strategies. One is to use a medication that has the fewest side effects, so that you won’t have drug-drug interactions with the patient if they’re on a numerous medicines for other concerns—their other symptoms and syndromes—that the antidepressant won’t interfere with it. And so along those lines, escitalopram and sertraline have the fewest drug-drug interactions. You essentially don’t need to look up drug-drug interactions if your patient is on one of those two medicines. The other approach is to say let’s choose a medicine that will have favorability with respect to the side effects, will be beneficial for the problems that the patient has. So a classic example is duloxetine is FDA-approved, not just for depression, not just for anxiety, but also for neuropathic and musculoskeletal pain. So here you’re talking about one treatment that will help you with the fact that your patient, their depression will get better; their neuropathic pain will get better if they have migraines—which are often a comorbidity—that will also benefit the neuropathic pain from that as well. And you know you will get two birds with one stone, as it were. And then the tricyclics, as you had asked about, we’ve had a lot of experience with them. They also will benefit in terms of the urinary incontinence problem. They are strongly anticholinergic, and so you can also benefit in terms of preventing the urinary/bowel problems. So really Cymbalta as just sort of son-of-tricyclics, has some fewer side effects, but doesn’t, therefore, cover some of the things that the tricyclics will. MSDF As you alluded to earlier, the depression in MS may largely be a result of immune processes going on—inflammation, cytokines, things like that. So how well do the disease-modifying therapies of MS attack the depression? Dr. Kaplin You know you mentioned cytokines. So that is another way that we know that this is due to the inflammation—the depression in MS—and not just other things, because for instance, interferon-alpha used to treat patients with hepatitis C will cause depression in upwards of 20 to 25% of people who take it, not when they first start it, but within you know a week to two weeks after starting it, you know, then up to eight weeks. So that’s just one cytokine, and in MS, all of the cytokines get activated. And similarly, interferon-beta that’s used, or Copaxone, you know, the ABCR drugs that we’ve used to try to—you know, with great effect since 1993—to slow the exacerbations down in MS; they don’t stop the inflammation, they just alter it. And so not surprisingly, they do not have antidepressant properties. But when you look at something like Tysabri, we actually have not published this yet. We did present it at a MS conference but working in collaboration with Biogen. We are going to publish shortly data that shows that, in a double-blind placebo-controlled study of adding natalizumab to Avonex, or adding placebo to Avonex, those patients who were depressed to begin with show a dramatic and statistically significantly decrease in their depression as a result of the natalizumab. So natalizumab is actually quite a good antidepressant—we have data for it—because that really does shut the inflammation down in the brain, and since that’s causing the depression in MS, that’s what benefits them. MSDF Just to clarify, natalizumab is a good antidepressant in MS. Dr. Kaplin Exactly right. That’s exactly right. Although, you know, it’s good that you clarified that. What’s interesting is that now that people are beginning to appreciate the role of the immune system in idiopathic depression, people are beginning to say, hmm, maybe we should be looking at these anti-inflammatories and seeing if the anti-inflammatories benefit patients with depression. Now, nobody has tried natalizumab, but TNF-alpha inhibitors have actually been tried. There was a study out of Emory looking at using TNF-alpha inhibitors for refractory depression. And I think coming down the road there will be more and more studies that begin to show the role of anti-inflammatories for not all, but some people with refractory depression. MSDF Yes, I’ve seen some studies on anti-inflammatories—traditional ones, NSAIDS sort of things—presented a German study at a neurology conference. Didn’t do too much. Dr. Kaplin Yes. What I can tell you is that not all NSAIDs are created equal. Celecoxib actually now has five studies that are placebo-controlled that have shown its benefit for depression or bipolar disorder. And so when added to antidepressant by itself: No. But when added to fluoxetine or—I can’t remember what other; it might have been sertraline—it clearly had a statistically significant improvement in the depression response, celecoxib. But not all NSAIDs are created the same. MSDF What about non-drug therapies, cognitive behavioral therapy, even just physical activity? And, if someone’s depressed, isn’t it hard to get them up and do physical activity? Dr. Kaplin Well, I’m so glad brought that up, because I’d be remiss to forget that. So all of the data says, look, therapies like cognitive behavioral therapy are effective for mild and moderate depression. Antidepressants are effective as well. The data shows that the antidepressants work quicker, but that the combination of antidepressants and psychotherapy is much better than either one alone. So that’s a crucial issue. And to make sense of what has happened—and often when people are depressed, they’ve been depressed, and that’s caused damage to their professional life and personal life, and having someone help them sort of, depending how long the depression’s been going on, sort of talk them through, coach them through, how to get back up and going. However, in severe depression, you can talk till the cows come home. If your patient is so depressed that basically they have this tunnel vision, and all of the options that are in front of them, the kind of mental flexibility that you need for CBT to work, for instance, it will not work if you patient is really severely depressed. You have to get them started with the antidepressant, which really then serves as a catalyst for the psychotherapy to kick in. And then the aspect of exercise, you can’t really pick a topic related to MS where the answer isn’t exercise. Cognitive impairment, absolutely exercise is beneficial. Depression, exercise is beneficial. It stimulates growth hormones that have positive neurological effects on the CNS, as well as on the peripheral nervous system and body. What I tell people, again, is that if your patient is severely depressed, they’re not going just go back out and start running. So you’ve got to begin to have a plan where you say, look, we’re going to begin this medicine. As you start to be able to have the ability to you know maybe push yourself more than you might usually and just sort of walk down the block, and then you know walk for a mile and then start jogging for a mile and sort of build up to it, that’s very beneficial. MSDF Are there barriers to recognizing and/or treating depression both on the patient’s side and on the physician’s side? Dr. Kaplin The big barrier on the physician’s side is, you know, don’t ask, don’t tell. So if you don’t think of depression, or worse, if the neurologist says, well, I went into neurology not psychiatry, you know, this whole depression thing, that’s not my bailiwick, that’s not my responsibility, you’re missing the fact that this is —first of all, this is very rewarding. There’s nothing else that you could treat that gets a patient from being non-functional, sitting at home, not taking care of the family, not working, in a bed to fully functional, taking care of the family, back at work, like treating the depression can. But also it is. It affects all aspects. It affects the patient’s compliance with all your other medicines. It affects their ability to exercise, etc., etc. So, you know, you’ve got to think of it. And then you have to know something about treating it. One of the big problems with neurologists when they treat depression is that they don’t appreciate the fact that the goal is to get that patient a hundred percent well, because you sort of have this sigma curve where, if you get them 50% well, they’re still in that sort of steep portion of the curve where something comes along—an MS attack or you even a viral infection—and they will slip right down that curve. Whereas, if you can push them way out into the hundred percent well, that’s great. Now you can’t always do it with one medicine. You take the dose as high as the patient can tolerate, where the side effects don’t become worse than the depression you’re trying to treat. But then you might need to add another medicine, an augmenting agent or something, so you’ve got to make sure you recognize it and treat it. And then, what I always tell my colleagues—and my colleagues at Hopkins are wonderful; they do appreciate you know you’re treating the whole patient, not just you know their reflex arcs and that kind of stuff—and what they are very good at is, if the patient is depressed and suicidal, that is the psychiatric equivalent of a heart attack. So then they will get in touch with me and we’ll work together. So if you’ve got someone who’s suicidal, you really want to get in touch. Unless you have the utmost experience and confidence in treating the worst cases of depression, you probably want to get a psychiatrist involved, or mental health professional involved, to help coordinate the care for someone like them. MSDF Very good! I appreciate it. [transition music] MSDF Thank you for listening to Episode Eighty-two of Multiple Sclerosis Discovery. This podcast was produced by the MS Discovery Forum, MSDF, the premier source of independent news and information on MS research. MSDF’s executive editor is Carol Cruzan Morton. Msdiscovery.org is part of the nonprofit Accelerated Cure Project for Multiple Sclerosis. Robert McBurney is our President and CEO, and Hollie Schmidt is Vice President of Scientific Operations. Msdiscovery.org aims to focus attention on what is known and not yet known about the causes of MS and related conditions, their pathological mechanisms, and potential ways to intervene. By communicating this information in a way that builds bridges among different disciplines, we hope to open new routes toward significant clinical advances. [outro music] We’re interested in your opinions. Please join the discussion on one of our online forums or send comments, criticisms, and suggestions to editor@msdiscovery.org. For Multiple Sclerosis Discovery, I'm Dan Keller.

Today we are discussing small fiber peripheral neuropathy, a condition that can independently be associated with severe foot and leg pain, but also is now being associated with fibromyalgia.  In today’s broadcast we will discuss new developments in the literature and seen in clinical practice that are being used to […]

Does Corinne remember her birthday party? Are you a bad friend if you can't find the right words after your gal pal gets molested? Do you want your dick owned? These questions and more are answered on this week's very special episode of #GuysWeFucked featuring Corinne's roommate/actor/fellow alpha female/Pinkerton's mom -- KRISTIN FRIEDLANDER! Kristin and the girls of Sorry About Last Night discuss roommate sex etiquette, the pros and cons of past gentlemen callers, the devastation of getting dumped for the first time, being the aggressor, how Cymbalta dries the puss, and what to do when that D is just 2 B. PLUS: Corinne & Krystyna reveal one of their dirtiest shared secrets. This episode is sponsored by www.poprageous.com

Ethics, legality and science behind debate about mentally ill criminals and the death penalty; Potential new law restricting mentally ill persons' access to guns; Lawsuits over Cymbalta discontinuation side effects.

Today in FirstWord:

Interlaced in singer-songwriter Jesse Macht’s catchy melodies are an abundance of stories overflowing with passion, vulnerability, empathy and honesty. Much like legendary songwriters before him such as Tom Petty and Neil Young, and modern day influences like Dan Wilson and Jon Brion, Jesse has proven his aptitude for storytelling. His music has been placed in many television shows and networks, as well as commercials, including The Voice, Keeping Up With The Kardashians, Giuliana and Bill, Nickelodeon, Cymbalta and the MTV/E! cable catalogue. He’s also had numerous original songs placed in independent films such as James Franco’s "Good Time Max." Jesse has followed a path similar to his family of entertainers (his brother is actor Gabriel Macht, currently starring in USA’s "Suits," and father is veteran actor Stephen Macht). He has worked hard to make a musical home for himself (both as a solo artist and with his old band Burn Down the Mission) within L.A.’s well-known songwriter community with regular appearances at the Hotel Café, Room 5 and WitZend. Jesse Macht connects with his audience through reflective, conversational lyrics. While his words are dynamic and unapologetically truthful at times, he leaves room for his audience to contribute to the dialogue by using their own experiences. The new album, expected to come out in the fall of 2014, follows Jesse’s 2012 debut solo release Acts of Providence. With it, he hopes to continue to inspire his audience and encourage them to be vulnerable.  For more information, please visit his official website here:  http://www.jessemachtmusic.com/ and follow him on Twitter at jessemachtmusic

Interlaced in singer-songwriter Jesse Macht’s catchy melodies are an abundance of stories overflowing with passion, vulnerability, empathy and honesty. Much like legendary songwriters before him such as Tom Petty and Neil Young, and modern day influences like Dan Wilson and Jon Brion, Jesse has proven his aptitude for storytelling. His music has been placed in many television shows and networks, as well as commercials, including The Voice, Keeping Up With The Kardashians, Giuliana and Bill, Nickelodeon, Cymbalta and the MTV/E! cable catalogue. He’s also had numerous original songs placed in independent films such as James Franco’s "Good Time Max." Jesse has followed a path similar to his family of entertainers (his brother is actor Gabriel Macht, currently starring in USA’s "Suits," and father is veteran actor Stephen Macht). He has worked hard to make a musical home for himself (both as a solo artist and with his old band Burn Down the Mission) within L.A.’s well-known songwriter community with regular appearances at the Hotel Café, Room 5 and WitZend. Jesse Macht connects with his audience through reflective, conversational lyrics. While his words are dynamic and unapologetically truthful at times, he leaves room for his audience to contribute to the dialogue by using their own experiences. The new album, expected to come out in the fall of 2014, follows Jesse’s 2012 debut solo release Acts of Providence. With it, he hopes to continue to inspire his audience and encourage them to be vulnerable.  For more information, please visit his official website here:  http://www.jessemachtmusic.com/ and follow him on Twitter at jessemachtmusic

Today in FirstWord:

Rene Thomas Folse, JD, Ph.D.is the host for this edition which reports on the following news stories. 6th District Court of Appeal Upholds WCAB in Guzman Case. Court of Appeal Softens Opinion on Ex Parte Communications With QME After Re-Hearing. Payment to Attend QME Appointment Does Not Start 104 Week Limit on TTD. Farmers Moves Simi Valley Employees to Woodland Hills. Travelers To Send an EOB Notice In All Workers' Compensation Claims Nationwide. Division of Workers' Compensation Unveils New EAMS Web Site Tools. Calif. Employers Face New Workers' Comp Posting Requirements. Workers' Comp Hammered By Recession, Experts Report. FDA Panel Backs Use of Eli Lilly's Cymbalta for Back Pain.

Guest: Stephen C. Ellen, MD Host: Leslie P. Lundt, MD Today we have many options to treat depression: the SSRIs, Cymbalta, Effexor, Emsam, Wellbutrin, just to name a few. How do you know when to move beyond the SSRIs? When is it time to refer to a psychiatrist? What if there are no psychiatrists available to your patients? Host Dr. Leslie Lundt welcomes Dr. Stephen Ellen to discuss the new age of psychopharmacological treatment of depression.