Podcasts about metabolic theory

What if everything we thought we knew about cancer was wrong? For decades, scientists have debated what really causes cancer. Is it genetic mutations, as the Somatic Mutation Theory suggests? Is it a metabolic dysfunction, as the Metabolic Theory argues? Or is there a deeper, overlooked truth—one that could redefine cancer treatment as we know it? In this episode, Dr. Ralph Moss and Ben Moss break down the battle between competing cancer theories, why conventional wisdom is being challenged, and what the latest research is uncovering about cancer stem cells, metabolism, and the Warburg Effect.

[Werbung]  Die Folge wird präsentiert von FreeStyle Libre Messystem – dem derzeit kleinsten und flachsten Sensor der Welt. Nach einer Aktivierungszeit von 60 Minuten misst der Sensor jede einzelne Minute. Weitere Infos und Hinweise zum FreeStyle Libre Messsystem: https://www.freestylelibre.de/produkte/freestyle-libre-3-entdecken.html [Werbung] Show Notes Weitere Infos zu FreeStyle Libre 3https://www.freestylelibre.de/produkte/freestyle-libre-3-entdecken.html www.freestylelibre.de Erwähnte Seiten, Blogs etc. Du hast Teil 1 verpasst? Hier findest Du ihn: https://zuckerjunkies.com/391-keto-live-project-josephine-barbarino/ Was liest Du, hast Du gelesen bzw. gehört (Hörbuch) und was kannst Du empfehlen? Dr. Georgia Ede „Change your Diet – Change your Mind“ auch super als Hörbuch von Ihr selbst gelesen Tripping over the Truth: How the Metabolic Theory of Cancer Is Overturning One of Medicine's Most Entrenched Paradigms by Travis Christofferson (Author), Dominic D'Agostino (Foreword) Kontaktdaten www.european-Keto-Live-Centre.com X @keto_live https://www.linkedin.com/in/josephine-barbarino-416a0042/ Spenden EKLC – The Non-Profit European Keto Live Centre Association for Ketogenic Metabolic Therapies Keto Live Project e.V. – VR meine Volksbank Raiffeisenbank e.G. IBAN:DE25 7116 0000 0002 4293 57 BIC:GENODEV1VRR SAKMT – The Non-Profit SWISS Association for Ketogenic Metabolic Therapies Swiss Association for KMT – Kantonalbank Graubünden IBAN: CH47 0077 4010 4656 7270 0

[Werbung]  Die Folge wird präsentiert von FreeStyle Libre Messystem – dem derzeit kleinsten und flachsten Sensor der Welt. Nach einer Aktivierungszeit von 60 Minuten misst der Sensor jede einzelne Minute. Weitere Infos und Hinweise zum FreeStyle Libre Messsystem: https://www.freestylelibre.de/produkte/freestyle-libre-3-entdecken.html [Werbung] Show Notes Weitere Infos zu FreeStyle Libre 3https://www.freestylelibre.de/produkte/freestyle-libre-3-entdecken.html www.freestylelibre.de Erwähnte Seiten, Blogs etc. Was liest Du, hast Du gelesen bzw. gehört (Hörbuch) und was kannst Du empfehlen? Dr. Georgia Ede „Change your Diet – Change your Mind“ auch super als Hörbuch von Ihr selbst gelesen Tripping over the Truth: How the Metabolic Theory of Cancer Is Overturning One of Medicine's Most Entrenched Paradigms by Travis Christofferson (Author), Dominic D'Agostino (Foreword) Kontaktdaten www.european-Keto-Live-Centre.com X @keto_live https://www.linkedin.com/in/josephine-barbarino-416a0042/ Spenden EKLC – The Non-Profit European Keto Live Centre Association for Ketogenic Metabolic Therapies Keto Live Project e.V. – VR meine Volksbank Raiffeisenbank e.G. IBAN:DE25 7116 0000 0002 4293 57 BIC:GENODEV1VRR SAKMT – The Non-Profit SWISS Association for Ketogenic Metabolic Therapies Swiss Association for KMT – Kantonalbank Graubünden IBAN: CH47 0077 4010 4656 7270 0

In this episode, Dr. Jockers joins Dr. Michael Karlfeldt to explore how metabolic flexibility can reduce cancer risk and support healing. They discuss the importance of helping your body switch between burning glucose and fat for better health.   You'll hear how fasting and time-restricted eating trigger autophagy, allowing the body to repair damaged cells. Lowering insulin levels plays a key role in activating this deep healing process.   Dr. Jockers and Dr. Karlfeldt also explain how reducing insulin and growth signals like mTOR helps prevent uncontrolled cell growth. By using nutrition and fasting, they reveal how to create a healing environment that weakens cancer cells.   In This Episode:    00:00 Understanding Metabolic Inflexibility 01:25 Unclogging Your Lymphatic System 02:53 Interview Introduction with Dr. Michael Karlfeldt  04:49 The Metabolic Theory of Cancer 09:04 The Role of Fasting and Diet in Cancer Prevention 16:07 The Importance of Insulin and Eating Windows 29:55 Hydration and Mineral Balance 30:38 Adjusting Meal Frequency and Timing 31:20 Fasting Strategies for Weight Loss 31:54 Fasting and Cancer Treatment 33:17 Press Pulse Strategy for Cancer 34:23 Oxidative Therapies in Cancer Treatment 47:33 Diet Principles for Metabolic Health 50:16 Protein Intake and Muscle Synthesis 54:52 Water Filtration and Hydration Tips 58:36 Conclusion and Final Thoughts     Are swollen legs or ankles slowing you down? Discover the power of Lymph System Support by Pure Health Research. Crafted with natural ingredients like dandelion extract, burdock root, and bromelain, this formula unclogs your lymphatic system, reducing swelling and supporting a healthy inflammatory response.   As a special offer, try Lymph System Support risk-free today and receive a complimentary bottle of curcumin extract. Visit GetLymphHelp.com/jockers to claim yours now. Say hello to renewed vitality and goodbye to discomfort!     Discover the power of Lion's Mane mushroom, now more bioavailable than ever with Purality Health's nano-absorption technology. Boost your memory, speed up your thinking, and elevate your mood effectively.   Don't miss the limited-time offer of buy one, get one free. Check it out with a six-month satisfaction guarantee at Lion's Mane Complex. Visit https://lionsmanecomplex.com/drj     “Cancer cells thrive on glucose; starve them by becoming metabolically flexible." - Dr. Michael Karlfeldt     Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean  TuneIn Radio     Resources: GetLymphHelp.com/jockers Visit https://lionsmanecomplex.com/drj   Connect with Dr. Karlfeldt: Website - https://www.thekarlfeldtcenter.com/   Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https://www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/ 

*Cool, Clear Water: Tune in NEXT FRIDAY to hear Dr. Gerald Pollack describe some mind blowing experiments revealing the beautiful sophistication of water! *Millions and Millions: Well a million anyway... RSR just went over 1 million views on YouTube! *X Marks the Shroud: Updating RSR's coverage, hear how Wide Angle X-Ray Scattering has dated the Shroud of Turin to around the time of Christ, and how the standard biblical refutation of a separate head cloth from John 20:7 may be explained in light of the linen cloth of Joseph of Arimathea in Matthew 27:59. *Big Bag of Nothing: Hear how the hunt for Dark Matter & WIMPs using LUX-ZEPLIN is going! *Revisiting Dr. Seyfried: Hear the latest from Dr. Pierre Kory on cancer research questioning the Somatic Mutation Theory & re-assessing the Metabolic Theory of cancer as described on RSR by Dr. Thomas Seyfried. *Cane These Hooligans! ...and the San Francisco Chronicle editorial board! The hooligans for destroying ancient sandstone formations, and the Chronical for claiming they know how they formed 40 million years ago. *Blondes Have More Follicles: It turns out his familiarity with the protective nature of melanin against UV damage of DNA was the key to helping Doug nail the Interesting Fact of the Week! *God and Elon Musk: The Wall Street Journal borrows credibility from both Jesus Christ and Elon Musk in order to get attention, and give RSR the opportunity to help Elon better understand the Bible! *Rescue Device: Hear about NASA's search for a vehicle to rescue the two astronauts that Boeing stranded on the International Space Station. *Working for Walt Brown: Astro-Alexandra makes another appearance on behalf of Walt Brown describing the sulfur found on Mars. *Melting, Modelling & Continental Formation: Fred covers another geo-physics  model that argues against plate tectonics!

*Cool, Clear Water: Tune in NEXT FRIDAY to hear Dr. Gerald Pollack describe some mind blowing experiments revealing the beautiful sophistication of water! *Millions and Millions: Well a million anyway... RSR just went over 1 million views on YouTube! *X Marks the Shroud: Updating RSR's coverage, hear how Wide Angle X-Ray Scattering has dated the Shroud of Turin to around the time of Christ, and how the standard biblical refutation of a separate head cloth from John 20:7 may be explained in light of the linen cloth of Joseph of Arimathea in Matthew 27:59. *Big Bag of Nothing: Hear how the hunt for Dark Matter & WIMPs using LUX-ZEPLIN is going! *Revisiting Dr. Seyfried: Hear the latest from Dr. Pierre Kory on cancer research questioning the Somatic Mutation Theory & re-assessing the Metabolic Theory of cancer as described on RSR by Dr. Thomas Seyfried. *Cane These Hooligans! ...and the San Francisco Chronicle editorial board! The hooligans for destroying ancient sandstone formations, and the Chronical for claiming they know how they formed 40 million years ago. *Blondes Have More Follicles: It turns out his familiarity with the protective nature of melanin against UV damage of DNA was the key to helping Doug nail the Interesting Fact of the Week! *God and Elon Musk: The Wall Street Journal borrows credibility from both Jesus Christ and Elon Musk in order to get attention, and give RSR the opportunity to help Elon better understand the Bible! *Rescue Device: Hear about NASA's search for a vehicle to rescue the two astronauts that Boeing stranded on the International Space Station. *Working for Walt Brown: Astro-Alexandra makes another appearance on behalf of Walt Brown describing the sulfur found on Mars. *Melting, Modelling & Continental Formation: Fred covers another geo-physics  model that argues against plate tectonics!

In this episode of The Rachel Hollis Podcast, Rachel interviews psychiatrist Dr. Chris Palmer from Harvard Medical School and McLean Hospital about the intersection of metabolism and mental health. They discuss the groundbreaking concept that mental illnesses such as schizophrenia, bipolar disorder, and depression might actually be metabolic disorders affecting the brain. Dr Palmer has been studying the use of the medical ketogenic diet as a path of treatment. Get the Start Today Journal - https://starttoday.com/products/start-today-journal00:00 Introduction: Finding Personalized Solutions01:45 Meet Chris Palmer: Psychiatrist and Researcher02:44 Traditional Psychiatry vs. New Perspectives08:06 The Metabolic Theory of Mental Disorders16:09 Global Trends in Mental Health and Metabolic Disorders20:37 The Ketogenic Diet: A Revolutionary Treatment28:47 Personal Journey and Early Discoveries29:50 Personal Mental Health Transformation30:22 Controversy and Reluctance to Share30:57 Moral Obligation to Share31:32 Nutrition and Mental Health Connection35:38 Impact of Hormones on Mental Health40:19 Personalized Medicine Approach45:18 Challenges in Psychiatry and Medication51:50 Support Systems and Holistic Health56:01 Conclusion and ResourcesHave a question you want Rach to answer? An idea for a podcast episode??Call the podcast hotline and leave a voicemail! Call (737) 400-4626Sign up for Rachel's weekly email: https://msrachelhollis.com/insider/Watch the podcast on YouTube: https://www.youtube.com/c/RachelHollisMotivation/videosFollow along on Instagram: https://www.instagram.com/MsRachelHollis/ To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices.

More than a billion people around the world suffer from mental and neurological disorders, and the numbers are escalating rapidly. Current treatments often fail to provide relief, resulting in many patients struggling with persistent symptoms and resistance to available therapies.In this episode, we're sharing a full presentation by world-renowned Harvard Psychiatrist, Dr. Christopher Palmer, filmed at Metabolic Health Summit 2024. Dr. Palmer presents a novel perspective that examines the potential link between metabolic dysfunction and mental illness. His theory, Brain Energy, proposes that metabolic dysfunction may serve as a unifying mechanism underlying various mental health conditions.Key highlights from this episode include: A dive into the surge in prevalence of mental disorders such as autism, ADHD, and depressionCurrent limitations and challenges within traditional treatment optionsEmerging evidence suggesting metabolic dysfunction as a potential root cause of mental illnessesThe role of the ketogenic diet and other innovative treatmentJoin us for an insightful exploration with Dr. Palmer as we examine how metabolism could reshape our understanding and treatment of mental health conditions.About Dr. Chris PalmerDr. Christopher M. Palmer is a Harvard psychiatrist and researcher working at the interface of metabolism and mental health. He is the Founder and Director of the Metabolic and Mental Health Program and the Director of the Department of Postgraduate and Continuing Education at McLean Hospital and an Assistant Professor of Psychiatry at Harvard Medical School. For almost 30 years, he has held administrative, educational, research, and clinical roles in psychiatry at McLean and Harvard. He has been pioneering the use of the medical ketogenic diet in the treatment of psychiatric disorders—conducting research in this area, treating patients, writing, and speaking around the world on this topic. Most recently, he has proposed that mental disorders can be understood as metabolic disorders affecting the brain, which has received widespread recognition in both national and international media outlets.Special Thanks to our Episode Sponsors: Genova Connect, powered by Genova Diagnostics: Receive 15% off any of their tests with code METABOLICLINK here.AirDoctor: Receive up to $300 off select air purifiers with code METABOLICLINK here.Timeline: Receive 10% off your first order of Mitopure. Use the code METABOLICLINK hereIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Welcome to The Nonlinear Library, where we use Text-to-Speech software to convert the best writing from the Rationalist and EA communities into audio. This is: The Cancer Resolution?, published by PeterMcCluskey on July 24, 2024 on LessWrong. Book review: The Cancer Resolution?: Cancer reinterpreted through another lens, by Mark Lintern. In the grand tradition of outsiders overturning scientific paradigms, this book proposes a bold new theory: cancer isn't a cellular malfunction, but a fungal invasion. Lintern spends too many pages railing against the medical establishment, which feels more like ax-grinding than science. I mostly agreed with his conclusions here, but mostly for somewhat different reasons than the ones he provides. If you can push through this preamble, you'll find a treasure trove of scientific intrigue. Lintern's central claim is that fungal infections, not genetic mutations, are the primary cause of cancer. He dubs this the "Cell Suppression theory," painting a picture of fungi as cellular puppet masters, manipulating our cells for their own nefarious ends. This part sounds much more like classical science, backed by hundreds of quotes from peer-reviewed literature. Those quotes provide extensive evidence that Lintern's theory predicts dozens of cancer features better than do the established theories. Older Theories 1. The DNA Theory (aka Somatic Mutation Theory): The reigning heavyweight, this theory posits that cancer results from an accumulation of genetic mutations in critical genes that control cell growth, division, and death. 2. Another old theory that still has advocates is the Metabolic Theory. This theory suggests that cancer is primarily a metabolic disease, characterized by impaired cellular energy production (the Warburg effect). It proposes that damage to mitochondria is a key factor in cancer development. I wrote a mixed review of a book about it. Lintern points out evidence that mitochondria are turned off by signals, not damaged. He also notes that tumors with malfunctioning mitochondria are relatively benign. Evidence Discrediting the DNA Theory The standard version of the DNA Theory predicts that all cancer cells will have mutations that affect replication, apoptosis, etc. Around 2008 to 2013, substantial genetic data became available for cancer cells. Lintern wants us to believe that this evidence fully discredits the DNA Theory. The actual evidence seems more complex than Lintern indicates. The strongest evidence is that they found cancers that seem to have no mutations. Almost as important is that the mutations that are found seem more randomly distributed than would be expected if they caused consistent types of malfunctions. Lintern's theory seems to explain all of the Hallmarks of Cancer, as well as a few dozen other features that seem to occur in all cancers. He argues that the DNA Theory does a poor job of explaining the hallmarks. DNA Theorists likely reject that characterization. They appear to have thought their theory explained the hallmarks back before the genetic data became available (mostly just positing mutations for each hallmark?). My guess is that they are busy adding epicycles to their theory, but the situation is complex enough that I'm having trouble evaluating it. He also points out that the DNA Theory struggles with Peto's Paradox (why don't larger animals get more cancer?), while his theory neatly sidesteps this issue. Additionally, mouse embryos formed from cancer cells showed no signs of cancer. Evidence of Fungi A key game-changer is the growing evidence of fungi in tumors. Until 2017, tumors were thought to be microbe-free. Now? We're finding fungi in all types of cancer, with tumor-specific fungal profiles. There's even talk of using fungal DNA signatures to distinguish cancer patients from healthy individuals. It's not a slam dunk for Lintern's theory, but it shifts the odds significantly. Medical Establishment Inertia It looks like people in the medical ...

Link to original articleWelcome to The Nonlinear Library, where we use Text-to-Speech software to convert the best writing from the Rationalist and EA communities into audio. This is: The Cancer Resolution?, published by PeterMcCluskey on July 24, 2024 on LessWrong. Book review: The Cancer Resolution?: Cancer reinterpreted through another lens, by Mark Lintern. In the grand tradition of outsiders overturning scientific paradigms, this book proposes a bold new theory: cancer isn't a cellular malfunction, but a fungal invasion. Lintern spends too many pages railing against the medical establishment, which feels more like ax-grinding than science. I mostly agreed with his conclusions here, but mostly for somewhat different reasons than the ones he provides. If you can push through this preamble, you'll find a treasure trove of scientific intrigue. Lintern's central claim is that fungal infections, not genetic mutations, are the primary cause of cancer. He dubs this the "Cell Suppression theory," painting a picture of fungi as cellular puppet masters, manipulating our cells for their own nefarious ends. This part sounds much more like classical science, backed by hundreds of quotes from peer-reviewed literature. Those quotes provide extensive evidence that Lintern's theory predicts dozens of cancer features better than do the established theories. Older Theories 1. The DNA Theory (aka Somatic Mutation Theory): The reigning heavyweight, this theory posits that cancer results from an accumulation of genetic mutations in critical genes that control cell growth, division, and death. 2. Another old theory that still has advocates is the Metabolic Theory. This theory suggests that cancer is primarily a metabolic disease, characterized by impaired cellular energy production (the Warburg effect). It proposes that damage to mitochondria is a key factor in cancer development. I wrote a mixed review of a book about it. Lintern points out evidence that mitochondria are turned off by signals, not damaged. He also notes that tumors with malfunctioning mitochondria are relatively benign. Evidence Discrediting the DNA Theory The standard version of the DNA Theory predicts that all cancer cells will have mutations that affect replication, apoptosis, etc. Around 2008 to 2013, substantial genetic data became available for cancer cells. Lintern wants us to believe that this evidence fully discredits the DNA Theory. The actual evidence seems more complex than Lintern indicates. The strongest evidence is that they found cancers that seem to have no mutations. Almost as important is that the mutations that are found seem more randomly distributed than would be expected if they caused consistent types of malfunctions. Lintern's theory seems to explain all of the Hallmarks of Cancer, as well as a few dozen other features that seem to occur in all cancers. He argues that the DNA Theory does a poor job of explaining the hallmarks. DNA Theorists likely reject that characterization. They appear to have thought their theory explained the hallmarks back before the genetic data became available (mostly just positing mutations for each hallmark?). My guess is that they are busy adding epicycles to their theory, but the situation is complex enough that I'm having trouble evaluating it. He also points out that the DNA Theory struggles with Peto's Paradox (why don't larger animals get more cancer?), while his theory neatly sidesteps this issue. Additionally, mouse embryos formed from cancer cells showed no signs of cancer. Evidence of Fungi A key game-changer is the growing evidence of fungi in tumors. Until 2017, tumors were thought to be microbe-free. Now? We're finding fungi in all types of cancer, with tumor-specific fungal profiles. There's even talk of using fungal DNA signatures to distinguish cancer patients from healthy individuals. It's not a slam dunk for Lintern's theory, but it shifts the odds significantly. Medical Establishment Inertia It looks like people in the medical ...

Episode Highlights With Katrina FoeThe root drivers of cancer and what we all need to know to avoid itLess than 10% of cancers are genetically inheritedThe root cause drivers of cancer and the tests that relate to themWhat the metabolic drivers of cancer arePreventative tests that can indicate early cancer riskHow hormones relate to cancerMicrobiome connections to cancer and what to know to improve itWhat angiogenesis is and why it mattersHow environmental toxins can relate to cancerThe emotional component to any diagnosis Why she got kicked out of the cancer treatment clinic and why she is so grateful for itHer take on coffee enemas Why too much protein isn't ideal with her cancer protocolThe therapeutic ranges for ketosisResources We MentionCancer FreedomInstagram - KatrinaNutritional Pilates: Relieve Joint Pain, Lose Unwanted Weight, and Prevent Chronic Disease to Become Your Most Vibrant Self by Katrina FoeTripping over the Truth: How the Metabolic Theory of Cancer Is Overturning One of Medicine's Most Entrenched Paradigms by Travis ChristoffersonThe Roadmap to Prevent Cancer Recurrence - Free ebook watercheck.comLevels Glucose MonitorKeto monitor

This week's episode is from a recent summit, and we are talking to Dr. Donese Worden, a pioneer researcher taking personalized medicine to the nth degree taking very special care of her cancer patients. She started out in the pain management space, but kept seeing cancer everywhere. The minute they had a diagnosis, they were thrown into chemo, radiation, and surgery, all before they even knew the name of their condition. Donese started digging and found the metabolic theory of cancer and began working with those researchers.You will hear:What is the metabolic theory of cancerHow to work with conventional oncologists to meet the patient's needs and wishesFinding ways to treat patients without also harming themThe best way to personalize treatment (genetics + environment)The benefits of a ketogenic diet and hyperbaric oxygen therapyAnd more!More about Dr. Worden: Dr. Donese Worden is a Naturopathic Medical Doctor, an expert diagnostician, a global health educator whose training in both conventional and alternative medicine affords her the privilege of providing each of her patients with a specific treatment plan that addresses not just the symptoms but the whole person to get to the root of the problem.Connect with Dr. Worden:Website: www.Dr Worden.comFacebook: https://www.facebook.com/DrDoneseWordenNMDInstagram: https://www.instagram.com/DrDoneseWorden/YouTube: https://www.youtube.com/user/DrDoneseWordenTo talk to a member of Dr. Jenn's team and learn more about working privately with RHMD, visit: https://calendly.com/stephanie-1031/time-to-talkTo get your copy of Dr. Jenn's book, The Smart Person's Guide to Breast Cancer, visit: https://realhealthmd.kartra.com/page/SmartPersonsGuidetoBreastCancerJoin the Facebook group: Facebook: https://www.facebook.com/groups/keepingabreastwdrjennConnect with Dr. Jenn:Website: https://www.realhealthmd.com/Facebook: https://www.facebook.com/DrJennSimmonsInstagram: https://www.instagram.com/drjennsimmons/YouTube: https://www.youtube.com/@dr.jennsimmons

Today we talk about three interconnected topics: hormones, sugar, and metabolic disease such as cancer and diabetes. Here's a link to the book that Dr. Bradford mentions: Tripping Over the Truth: How the Metabolic Theory of Cancer is Overturning One of Medicine's Most Entrenched Paradigms, by Travis Christofferson -- Views expressed here are our own or those of our guests. This show should not be taken as medical advice. Please consult with your personal physicians regarding anything we say. Connect with our office online at ⁠⁠https://downtowngilberthealthcare.com⁠⁠ or on Facebook at ⁠⁠https://facebook.com/downtowngilberthealthcare⁠⁠ Follow Dr. Dan on TikTok: ⁠⁠@doctordantheman⁠⁠ Find Dr. Bradford on Gab: ⁠⁠@abnd⁠⁠ --- Send in a voice message: https://podcasters.spotify.com/pod/show/communityguidelines/message Support this podcast: https://podcasters.spotify.com/pod/show/communityguidelines/support

Dr. Nasha Winters discusses The Metabolic Theory of Cancer with Dr. Ben Weitz. [If you enjoy this podcast, please give us a rating and review on Apple Podcasts, so more people will find The Rational Wellness Podcast. Also check out the video version on my WeitzChiro YouTube page.]    Podcast Highlights 1:30  Cancer is more likely caused by mitochondrial damage, often related to the metabolic environment in our bodies and related to the modern diet and toxins, et cetera, rather than primarily caused by somatic DNA mutations.  Dr. Theodor Boveri, a German zoologist, comparative anatomist and co-founder of modern cytology, first proposed the somatic mutation or genetic theory of cancer in 1914.  We have taken this theory and run with it for the last 109 years without really proving it. At about the same time, Otto Warburg had proposed the metabolic/mitochondrial theory of cancer and it was outpacing the somatic theory until the 1950s when Watson and Crick found the DNA helix and everyone went back to the genetic theory of cancer. Nixon launched the war on cancer 52 years ago but given the increase in the number of people being diagnosed with and dying of cancer continues to grow, we are sadly not winning this war.  We mapped the human genome and we hoped that this would provide more answers, but it really just raised more questions than answers. And clearly the one gene, one target, one cause is not what we had hoped it would be.  Also, multiple studies using a nuclear cell transfer have been unable to create cancer in a cell by transferring the nuclei out of a cancer cell into a healthy cell.  This demonstrates that cancer is not caused primarily by somatic mutations. 6:08  We have been able to show that the mitochondria not only make energy but are the protectors of our DNA and our genetic expression. Unfortunately, most of the therapies we use to treat our genes, like chemotherapy, only further damage the mitochondria, which then make us even more vulnerable to recurrence, progression, and even having a cancer diagnosis to begin with.  What affects the mitochondria are everything we put in, on, and around us, from food, to thoughts, to water, to the people around you, to the environments you live in, to the light you're exposed to, to the chemicals you put on your skin and spray in your gardens.  Your mitochondria are signaling agents and they take in information and translate it into the body.  We can have a big impact on the environment in our bodies by how we lead our lives, which can either drive cancer growth or make it more difficult for cancer to thrive.  With the genetic theory, it's just bad luck and there's nothing that you can do about it. 12:11  Blood Sugar.  High glucose levels can increase free radicals and lead to DNA mutations. Sugar in the body creates glycosylated end products, which essentially means that you are oxidizing or rusting your innards.  Hemoglobin A1C is a blood test that measures this glycosylation.  We can also measure certain cytokines that direct the inflammation.  When glucose is high, it stimulates cortisol and estrogens and these things impact glucose as well.  High insulin levels also blunt your immune response.  We can literally treat disease by what is on the end of our fork. 15:15  New targeted therapies.  For decades conventional cancer care has consisted of chemo, radiation, and surgery. But now we have newer more targeted therapies, including immunotherapy, CAR T-cell therapy, etc.  Before commenting about the new therapies, Dr. Winters pointed out that there is a better way to utilize the standard of care like chemotherapy.  When you pair metronomics with chemotherapy at a dose less than 20% and pair this also with natural stressors, like fasting, hyperbaric oxygen, and other natural therapies, you get more effectiveness with fewer side effects. This is using chemo smarter.  When it comes to the newer therapies like immunotherapy,

Nels and Vincent explain a study of how interspecies competition between two algae influences evolution of metabolism and size. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiEVO Links for this episode •Join the MicrobeTV Discord server • Metabolic evolution during competition (Curr Biol) Science Picks Nels – How amino acids got their names (Source) Vincent – EVs Fix One Pollution Problem—And Worsen Another Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

Given that mental health treatment outcomes have not improved dramatically over time despite a wealth of research, novel psychotherapies and pharmaceutical compounds, it is important that new theories around mental disorders continue to be identified and explored.   Harvard psychiatrist & researcher, Dr. Chris Palmer, joins us for a discussion of some of the core themes in his new book Brain Energy, which paints the picture of a potential “unifying” underlying metabolic mechanism with respect to mental disorders that might allow better understanding and treatment of brain illness.  In this conversation we cover:the client journey that led Dr. Palmer to want to write this bookan overview of Dr. Palmer's conceptualization of mental disorders, including differenting between expected and adaptive responses to stressors vs. true brain disorders a review of some of the findings that have suggested a link between metabolic processes and the evolution & maintenance of mental disorders and how this model accommodates comorbiditythe importance of neuronal activation - both over- and under-activation - in Dr. Palmer's modelthe risk factors that contribute to developing a metabolic disorder within the brainimplications of the Brain Energy model with respect to why established pharmacotherapy (or even psychotherapy) might actually workmedical & self-help treatments that this model suggests might be helpful, including the role of supplements & medications which impact upon metabolismHost note: We will be offering a 6 week essentials of CBT workshop that I will be facilitating beginning March 24, 2023.  For more information and registration, please visit: https://www.ottawacbt.ca/news Please come join us!Dr. Christopher M. Palmer is a Harvard psychiatrist and researcher working at the interface of metabolism and mental health. He is the Director of the Department of Postgraduate and Continuing Education at McLean Hospital and an Assistant Professor of Psychiatry at Harvard Medical School. For over 25 years, he has held administrative, educational, research, and clinical roles in psychiatry at Harvard. He has been pioneering the use of the medical ketogenic diet in the treatment of psychiatric disorders—conducting research in this area, treating patients, writing, and speaking around the world on this topic. Most recently, he has proposed a comprehensive theory of what causes mental illness, integrating existing theories and research into one unifying theory—the brain energy theory of mental illness.https://brainenergy.com/

Travis Christofferson is a returning guest on our show! Be sure to check out his first appearance on episode 127 of Boundless Body Radio, which is one of our most downloaded of all time! Travis Christofferson has a degree in molecular biology and a master's degree in material engineering and science. He is a full-time science writer and published the best-selling book Tripping over the Truth: How the Metabolic Theory of Cancer Is Overturning One of Medicine's Most Entrenched Paradigms which follows the story of cancers proposed metabolic origin from the vaunted halls of the German scientific golden age, to modern laboratories around the world. He is also the author of Ketones, The Fourth Fuel: Warburg to Krebs to Veech, the 250 Year Journey to Find the Fountain of Youth, and the book we discussed today, Curable: How an Unlikely Group of Radical Innovators Is Trying to Transform our Health Care System. He is the founder of The Foundation for Metabolic Cancer Therapies, and the co-founder of Care Oncology.Find Travis at-foundationformetaboliccancertherapies.comTW- @tchristoff1Check out these fascinating fasting studies conducted by George Cahill!Find Boundless Body at-myboundlessbody.comBook a session with us here! 

We don't often look at preventative measures when it comes to our health. We typically look for ways to get better after we get sick — take a pill or undergo this operation, and everything will be better! Don't put off becoming more health-conscious until you've been diagnosed with a disease like cancer. The adage still holds: prevention is better than a cure. In this episode, Best Selling Science Author++ Travis Christofferson discusses the root causes of diseases and how we can take a preventive approach to health. He shares emerging cancer treatment research and encourages us to learn more about them. Focus on your overall health rather than specific diseases. When your body has a good immune system, it can help prevent illnesses like cancer!  If you want to learn more about the latest in cancer research disease prevention, then this episode is for you! Here are three reasons why you should listen to the full episode: Understand the root causes of diseases and how we can prevent them rather than waiting for illness. Learn about emerging cancer treatment research, including the metabolic approach, ketosis, abscopal effect, etc.  The state of our health care systems Get Customised Guidance for Your Genetic Make-Up For our epigenetics health programme, all about optimising your fitness, lifestyle, nutrition and mind performance to your particular genes, go to  https://www.lisatamati.com/page/epigenetics-and-health-coaching/. Customised Online Coaching for Runners CUSTOMISED RUN COACHING PLANS — How to Run Faster, Be Stronger, Run Longer  Without Burnout & Injuries Have you struggled to fit in training in your busy life? Maybe you don't know where to start, or perhaps you have done a few races but keep having motivation or injury troubles? Do you want to beat last year's time or finish at the front of the pack? Want to run your first 5-km or run a 100-miler? ​​Do you want a holistic programme that is personalised & customised to your ability, goals, and lifestyle?  Go to www.runninghotcoaching.com for our online run training coaching. Health Optimisation and Life Coaching Are you struggling with a health issue and not getting anywhere with the traditional medical system and need people who look outside the square who are up on the cutting edge of research and are connected to some of the greatest science and health minds in the world? Then reach out to us at lisa@lisatamati.com, we can jump on a call to see if we are a good fit for you. Mindset and Mental Toughness coaching. If you have a big challenge ahead, are dealing with adversity or want to take your performance to the next level and want to learn how to increase your mental toughness, emotional resilience, foundational health, and more, contact us at lisa@lisatamati.com. Order My Books My latest book Relentless chronicles the inspiring journey about how my mother and I defied the odds after an aneurysm left my mum Isobel with massive brain damage at age 74. The medical professionals told me there was absolutely no hope of any quality of life again. Still, I used every mindset tool, years of research and incredible tenacity to prove them wrong and bring my mother back to full health within three years. Get your copy here: https://shop.lisatamati.com/collections/books/products/relentless. For my other two best-selling books Running Hot and Running to Extremes, chronicling my ultrarunning adventures and expeditions all around the world, go to https://shop.lisatamati.com/collections/books. Lisa's Anti-Ageing and Longevity Supplement Range NMN: Nicotinamide Mononucleotide, an NAD+ precursor Quercetin and Trimethlyglycine by NMN Bio Feel Healthier and Younger* Researchers have found that Nicotinamide Adenine Dinucleotide or NAD+, a master regulator of metabolism and a molecule essential for the functionality of all human cells, is being dramatically decreased over time. What is NMN? NMN Bio offers a cutting edge Vitamin B3 derivative named NMN (beta Nicotinamide Mononucleotide) that can boost the levels of NAD+ in muscle tissue and liver. Take charge of your energy levels, focus, metabolism and overall health so you can live a happy, fulfilling life. Founded by scientists, NMN Bio offers supplements of the highest purity and rigorously tested by an independent, third-party lab. Start your cellular rejuvenation journey today. Support Your Healthy Ageing We offer powerful third-party tested NAD+ boosting supplements so you can start your healthy ageing journey today. Shop now: https://nmnbio.nz/collections/all NMN (beta Nicotinamide Mononucleotide) 250mg | 30 capsules NMN (beta Nicotinamide Mononucleotide) 500mg | 30 capsules 6 Bottles | NMN (beta Nicotinamide Mononucleotide) 250mg | 30 Capsules 6 Bottles | NMN (beta Nicotinamide Mononucleotide) 500mg | 30 Capsules Quality You Can Trust — NMN Our premium range of anti-ageing nutraceuticals (supplements that combine Mother Nature with cutting edge science) combats the effects of aging while designed to boost NAD+ levels. Manufactured in an ISO9001 certified facility Boost Your NAD+ Levels — Healthy Ageing: Redefined Cellular Health Energy & Focus Bone Density Skin Elasticity DNA Repair Cardiovascular Health Brain Health  Metabolic Health   Perfect Amino Supplement by Dr David Minkoff Introducing PerfectAmino PerfectAmino is an amino acid supplement that is 99% utilized by the body to make protein. PerfectAmino is 3-6x the protein of other sources with almost no calories. ​100% vegan and non-GMO. ​The coated PerfectAmino tablets are a slightly different shape and have a natural, non-GMO, certified organic vegan coating on them so they will glide down your throat easily. Fully absorbed within 20-30 minutes! ​No other form of protein comes close to PerfectAminos Ketone Products by Keto-Pro Exogenous Ketones developed by Nutritionist and Body Building champion Richard Smith. Keto-Pro BHB Exogenous Ketones –  250g   MORE BHB per gram than other MARKET LEADERS. During In-house testing, Keto-Pro BHB raised ketones quicker, higher and for longer than other market leaders. Ketones My  ‘Fierce' Sports Jewellery Collection For my gorgeous and inspiring sports jewellery collection, 'Fierce', go to https://shop.lisatamati.com/collections/lisa-tamati-bespoke-jewellery-collection. Episode Highlights [03:17] Travis' Background Travis has an undergraduate degree in biochemistry. He eventually took over the family business and got married.  He then finished his master's degree, focusing on cancer metabolism for his independent study. The prevailing teaching during that time was that somatic mutations cause cancer. Travis was inspired by the book, Cancer as a Metabolic Disease, to do a thesis on metabolic theory.  Otto Warburg proposed the metabolic theory many years ago, but the medical community dismissed it as simplistic. New evidence reignited interest in the approach. [08:10] The State of Healthcare Public and health institutions have long accepted the somatic approach to cancer, with billions of dollars backing it.  The United States spends the most per capita on health care expenditure among developed countries yet has the lowest life expectancy.  The issue with the healthcare system lies in variations of treatment, over-treatment, and drug development process.  The healthcare industry is focused more on treating diseases rather than preventing them.   Although technology has advanced to assist people in tracking their health, people's health is deteriorating. Even if people live longer, they often experience illness and disability in their final years. [12:48] Changing the Healthcare Industry  The healthcare incentive structure must change. Doctors get paid for every drug and procedure they prescribe, leading to overtreatment.  There are emerging practices where doctors get a big bonus per patient who doesn't need procedures, encouraging them to keep patients in good health. When blood sugar levels rise, doctors usually diagnose diabetes. However, we can test for fasting insulin regularly to intervene. This test can also help people prevent other diseases and become more health-conscious. Change takes time with systems and industries, but we can take simple lifestyle interventions now. [16:01] Why People Are Getting Sicker Maintaining our health can be challenging. We've been conditioned that taking a magic pill is preferable to putting in the effort. Remember that metabolic dysregulation causes aging, not the other way around. In the last 10,000 years, humanity has drastically shifted to consuming processed foods, carbohydrates, and oils, resulting in noticeable consequences. People have also become sedentary.  A hunter-gatherer society has no obesity, insulin resistance, or chronic systemic inflammation. However, we frequently see this in the Western world. [20:32] The Root of Diseases  Understanding cellular health and inflammatory processes are critical in keeping yourself healthy.  Periods of food scarcity have happened throughout humanity's evolution. Our bodies enter ketosis due to the caloric deficit but most never reach this state. Studies have shown that ketosis can help prevent diseases ranging from Alzheimer's to Parkinson's to cancer and diabetes. Constantly eating keeps our immune system active and prevents it from resting, which has implications for chronic inflammatory diseases. [24:53] What Happens During Ketosis?  Ketosis happens in a fasted state, and a ketogenic diet is nutritional maintenance. When we fast, our bodies will mobilise the fat we have in our bodies and begin a process of beta-oxidation to burn off fat.  A caloric deficit makes this process faster, converting fats into ketone bodies, which then take the place of glucose.  Ketones have more thermodynamic energy and ATP per carbon unit compared to glucose.  Ketosis also boosts antioxidant levels. Since diseases are oxidative, ketosis can help to combat illnesses. Listen to the episode to learn more!  [32:01] Growing Healthcare Trends  Research has shown that fasting before chemotherapy can reduce some radiation side effects Sugar is fuel for cancer cells, but doctors continue giving and allowing patients to consume it.  There's more awareness of the latest research. The annual Metabolic Therapeutic Conference has grown to around 1600 attendees.    When we approach doctors, we will receive information their institution has taught and allowed them to give us. Even with COVID-19, people have yet to explore treatments like monoclonal antibodies, hyperbaric, and Vitamin C.  [44:00] The Abscopal Effect on Cancer The abscopal effect is when you target a single tumour site, but it affects other tumour sites in the body.  Travis shares a case where someone with breast cancer on a checkpoint inhibitor received a much lower radiation dose.  In that case, radiation was sufficient to systematically stimulate the immune system to attack cancer, improving the patient's chances of survival. [47:41] Advancements in Immunotherapy Using peptides to manipulate the immune system is still a trial and error process. The immune system's job is to survey for cancer, get rid of it early, and create a checkpoint to avoid attacking itself.  [49:44] Emerging Cancer Treatment Research In detection, metastasis is an early stage event rather than a late-stage one. Cancer cells break off, dying when it reaches the bloodstream.  This selection pressure creates different genetic mutations in tumours.  The somatic mutation theory argues that a series of sequential mutations cause cancer, with each tumour site having a unique set of driving mutations. The epigenetic metabolic theory posits that these mutations are a side effect of the disease.  All cancers burn sugar and evade the immune system, but mutations vary too much. Treatments should focus on epigenetic expression rather than mutations. [55:16] Researching Treatment Options The medical field is filled with uncertainty. Cancer treatment options have not been compared.  After an in-depth look at clinical trials, we find that what seems to be the best treatment paradigm isn't always the right option. When conducting research, consider the data and evaluate it using a risk-reward framework. You can choose from low-risk alternatives. [59:59] The Soil Approach to Cancer  Cancer grows in the presence of a favourable microenvironment and molecular events. It takes a long time for a chronic irritant to develop cancer cells. Cancer cells take on characteristics of our earliest genes,  including replication and the appearance of early embryos. You can help your cells "behave" by providing oxygen and avoiding chronic irritants. Nurture the microenvironment through exercising and eating the right foods.  Instead of focusing on the seed or cancer, we should concentrate on the soil or microenvironment. [1:04:05] Health and Longevity While we don't know humankind's natural and optimal states, ketosis and fasting provide a glimpse. Cells stop metabolising as we age, causing inflammation. We may be able to extend life spans if we can reduce senescent cells. Travis shares a study in which mice received fisetin, found in strawberries, reducing senescent cells and prolonging their life.  There's a lot of new research on substances that kill senescent cells, like senolytics, quercetin, and other compounds. [1:08:49] About StageZero Life Sciences  StageZero Life Sciences looks into markers of inflammation, insulin resistance, etc. They also recommend potential lifestyle interventions to change those markers.  They are currently available in Richmond, Virginia, Toronto, and Ontario, Canada. 7 Powerful Quotes 'It's just a combination of probably a terrible diet and just not moving enough because we were designed to go out and have to work every day to catch food. That's what we evolved, and when you uncouple your physiology from that environmental niche, you see all kinds of problems' ‘It appears that evolution has built in a powerful signal to that when you're in a caloric deficiency, you switch your metabolism…to something called ketosis where you completely shift what you're burning to these little small molecules that come from fat,' ‘We're terrible at focusing on prevention. We focus on the disease, trying to treat it once it's already manifest, which is an absolutely horrible strategy.' ‘If we look at cancer then as the prime drivers being metabolic and epigenetic, that means that all of those things potentially could be modifiable, right? We don't have to target mutations. We can look for ways to change the way cells are expressing genes and so forth, and metabolising substrates and things like that.' ‘Just mind the microenvironment of your body, which is giving you the right food, exercising. It's designed to do that. Every time you do that, it brings down those inflammatory processes, and so forth.' ‘We tend to think we're in this modern era, but with regard to cancer, we will look back 200 years from now, realise that we were just in the Dark Ages. We're still using radiation which was invented about 110 years ago; chemotherapy was invented around World War II. That's still the mainstay of cancer treatments.' ‘When you really look deep, the two problems really are variation in treatment, over-treatment. The drug development process, I think, is one of the main problems too,' Resources Gain exclusive access and bonuses to Pushing the Limits Podcast by becoming a patron!  Want to learn more from Travis? Check out his books:  Tripping Over the Truth: How the Metabolic Theory of Cancer is Overturning One of Medicine's Most Entrenched Paradigms  Curable: How an Unlikely Group of Radical Innovators is Trying to Transform our Health Care System Ketones, The Fourth Fuel: Warburg to Krebs to Veech, the 250 Year Journey to Find the Fountain of Youth The Origin (and future) of the Ketogenic Diet, co-authored with Dr Dom D'Agostino   Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer by Thomas Seyfried  Emperor of All Maladies: A Biography of Cancer by Siddhartha Mukherjee The Cancer Code: A Revolutionary New Understanding of a Medical Mystery by Dr Jason Fung  Healthy Conversations With Travis Christofferson and Guest, Jason Fung M D from StageZero Life Sciences   Check out these previous episodes with Dr Elena Seranova:  Episode 238 - Reverse Ageing to Live Longer and Healthier Episode 189 - Understanding Autophagy and Increasing Your Longevity Episode 183 - Sirtuins and NAD Supplements for Longevity    Learn more about cancer and health through our previous episodes:  The Six Cornerstones for Better Health with Dr Charles Meakin Cancer Revolution: The Metabolic Approach to Cancer with Maggie and Bradley Jones   Abscopal effect following radiation monotherapy in breast cancer: A case report Fisetin is a senotherapeutic that extends health and lifespan Short-term fasting accompanying chemotherapy as supportive therapy in gynecological cancer: protocol for a multicenter randomised controlled clinical trial StageZero Life Sciences: Website | AVRT Program Foundation for Metabolic Cancer Therapies    Connect with Travis:  LinkedIn | Twitter | Facebook    About Travis  Travis Christofferson is the founder of The Foundation for Metabolic Cancer Therapies and works in Clinical Development at StageZero Life Sciences Ltd.  He is also a science author of several books, including Tripping Over the Truth: How the Metabolic Theory of Cancer Is Overturning One of Medicine's Most Entrenched Paradigms, Curable: How an Unlikely Group of Radical Innovators Is Trying to Transform Our Health Care System, Ketones, The Fourth Fuel, and co-author of The Origin (and future) of the Ketogenic Diet.  Want to learn more about Travis' work? Check out Foundation for Metabolic Cancer Therapies.  You can also connect with him on LinkedIn, Twitter, and Facebook.    

Most of us go about our lives, assuming that the changes we may feel in our bodies are simply signs of aging. When we're sick, we look for treatments and quick fixes.  A more proactive approach to your health could save you from the financial and emotional distress that comes with a scary diagnosis.  In this episode, Dr Charles Meakin discusses how Care Oncology has provided early detection services, along with alternative and additional treatments for cancer patients. He talks about the benefits of disease prevention, particularly cancer prevention. He also shares the six fundamentals for better health and encourages us to live healthier, even if we don't suffer from diseases.  Read the episode if you want to learn more about cancer and disease prevention through better life practices! Here are three reasons you should listen to the full episode: Understand how Care Oncology is providing accessible options for cancer detection and treatment. Find out the four drugs on which the company is focusing its efforts. Discover Dr Charles' six fundamentals for better health.  Learn to see threats as opportunities and be able to stay consistent.  Get Customised Guidance for Your Genetic Make-Up For our epigenetics health program, all about optimising your fitness, lifestyle, nutrition, and mental performance to your particular genes, go to  https://www.lisatamati.com/page/epigenetics-and-health-coaching/. Customised Online Coaching for Runners CUSTOMISED RUN COACHING PLANS — How to Run Faster, Be Stronger, Run Longer Without Burnout & Injuries Have you struggled to fit into training in your busy life? Maybe you don't know where to start, or perhaps you have done a few races but keep having motivation or injury troubles? Do you want to beat last year or finish at the front of the pack? Want to run your first 5-km or run a 100-miler? ​​Do you want a holistic program that is personalised & customised to your ability, goals, and lifestyle?  Go to www.runninghotcoaching.com for our online run training coaching. Health Optimisation and Life Coaching Are you struggling with a health issue and need people who look outside the square and are connected to some of the world's greatest science and health minds? Then reach out to us at support@lisatamati.com, and we can jump on a call to see if we are a good fit for you. If you have an enormous challenge ahead, are dealing with adversity, or want to take your performance to the next level and learn how to increase your mental toughness, emotional resilience, foundational health, and more, contact us at support@lisatamati.com. Order My Books My latest book, Relentless, chronicles the inspiring journey of how my mother and I defied the odds after an aneurysm left my mum Isobel with massive brain damage at age 74. The medical professionals told me there was absolutely no hope of any quality of life again. Still, I used every mindset tool, years of research, and incredible tenacity to prove them wrong and bring my mother back to full health within three years. Get your copy here: https://shop.lisatamati.com/collections/books/products/relentless. For my other two best-selling books Running Hot and Running to Extremes, chronicling my ultra-running adventures and expeditions all around the world, go to https://shop.lisatamati.com/collections/books. Lisa's Anti-Ageing and Longevity Supplements  NMN: Nicotinamide Mononucleotide, an NAD+ precursor Feel Healthier and Younger* Researchers have found that Nicotinamide Adenine Dinucleotide or NAD+, a master regulator of metabolism and a molecule essential for the functionality of all human cells, is being dramatically decreased over time.  What is NMN? NMN Bio offers a cutting-edge Vitamin B3 derivative named NMN (beta Nicotinamide Mononucleotide) that can boost the levels of NAD+ in muscle tissue and the liver. Take charge of your energy levels, focus, metabolism, and overall health to live a happy, fulfilling life. Founded by scientists, NMN Bio offers supplements of the highest purity and is rigorously tested by an independent, third-party lab. Start your cellular rejuvenation journey today. Support Your Healthy Aging We offer powerful third-party tested NAD+ boosting supplements so you can start your healthy aging journey today. Shop now: https://nmnbio.nz/collections/all NMN (beta Nicotinamide Mononucleotide) 250mg | 30 capsules NMN (beta Nicotinamide Mononucleotide) 500mg | 30 capsules 6 Bottles | NMN (beta Nicotinamide Mononucleotide) 250mg | 30 Capsules 6 Bottles | NMN (beta Nicotinamide Mononucleotide) 500mg | 30 Capsules Quality You Can Trust — NMN Our premium range of anti-aging nutraceuticals (supplements that combine Mother Nature with groundbreaking science) combats the effects of aging while designed to boost NAD+ levels—manufactured in an ISO9001 certified facility. Boost Your NAD+ Levels — Healthy Aging: Redefined Cellular Health Energy & Focus Bone Density Skin Elasticity DNA Repair Cardiovascular Health Brain Health  Metabolic Health My 'Fierce' Sports Jewellery Collection For my gorgeous and inspiring sports jewellery collection, 'Fierce,' go to https://shop.lisatamati.com/collections/lisa-tamati-bespoke-jewellery-collection. Episode Highlights [03:45] Dr Charles' and Care Oncology's Background  Charles has worked in oncology for 30 years. He started working at a big hospital in Charlotte, but pivoted after becoming legally blind.  He eventually discovered Care Oncology, a company that applies metabolic strategies for cancer treatment.  Care Oncology was started by Robin Bannister, a pharmacist and drug developer. His wife had developed stage-four breast cancer and had exhausted all treatment options.  Robin selected four drugs commonly used for non-cancer disorders but were found to affect cancer.  Robin selected four drugs based on human data, safety, non-overlapping effects, and their benefits for other chronic conditions.  [08:46] Care Oncology's Approach Care Oncology uses metformin, atorvastatin, doxycycline, and mebendazole. The company kept to the dosage of the four drugs within a specific range.  Additional drugs, like Prozac and oxaloacetate, also proved helpful along with the metabolic approach.  Over the years, cancer research has focused more on the somatic mutation theory than the metabolic theory.  The metabolic approach to cancer is slowly becoming more widespread.  Even Dr Weinberg, who championed the hallmarks of cancer, added three more hallmarks that are purely metabolic.    [16:52] Diet and Future of the Metabolic Approach From a somatic perspective, diet is not very important to curing cancer; however, food does affect cancer.  The standard American diet of proteins and fruits and grains can cause issues for cancer patients. Care Oncology has recently merged with Stage Zero Life Sciences for early detection. They perform blood biopsies and are looking into the RNA expression of white blood cells.  Early detection technology is slowly becoming more available.  As the company expands, they intend to add various types of cancers to their treatment list. . Learn about Care Oncology's testing process by listening to the full episode.  [30:38] What Care Oncology Prioritises Charles shares that Care Oncology prioritises the markers with the most impact, as nuanced tests are more expensive.  The death rate from cancer may decrease, but the cancer rate is increasing. He shares how one in three women who get breast cancer become bankrupt after treatments. Care Oncology wants to reverse this experience by providing cheaper early detection methods through blood biopsies. Their process includes follow-ups and discussions.  Their State Zero tests are currently available only in the US, but the company hopes to expand over time.   [36:28] Why Early Detection is Important  Tests can predict patterns before cancer physically manifests.  It's important to get regular physicals, lifestyle checks, and screenings every 18 months to 2 years.  The earlier you detect cancer, the higher the survival rate. . Early detection can also mean less expensive. According to Charles, colon cancer detected in stage one has a 90% chance of being cured. However, the later the cancer is detected, the lower the chance of being cured. It costs more to fix something than to prevent something.  [43:11] There's No One Treatment for Everyone Charles shares that his best outcomes were when he customised treatments based on patients' needs. Unfortunately, cancer treatment is often too focused on following guidelines.  It's important for patients to have hope that they can get better.  Unfortunately, physicians have little time to fully engage with patients. There is no “right way” to treat cancer. What works for one patient may not work for others. Talk to your doctors about what you're putting in your body. This also applies to the vaccine and diet.  [56:12] Balance is Key  It's important to be aware of your sugar intake. A patient's BMI can have an impact on the success of treatments.  Charles recommends intermittent fasting with a diet of animal protein, healthy fats, and low fructose fruits. Couple this diet with micro-exercises before and after meals.  Our muscles are the biggest organ in our body, and they can act as metabolic neutralizers.  Make sure your meals are balanced. Remember to consider your sleep and mood.   [1:01:48] Find Opportunities  Everything can be seen as an opportunity to learn more about yourself and to grow.  See things as a challenge instead of a threat. Not everyone has a growth mindset, but people will ‌develop this by identifying their purpose.  [1:06:32] Dr Mekin's Recommendations: BEGSIS First, nostril breathing.  Second, eat only real foods made up of fats, proteins, and low carbohydrates. Keep yourself hydrated.  Get moving to maintain and enhance your functionality.  Sleep. Make sure you recover and have your rhythms in order.  Have intent and always have a mission bigger than yourself.  Be social and involve yourself with others. Social isolation is a predictor of demise.   [1:10:37] Focus on Fundamentals  With everything happening in the world, it's easy to focus on the negative.  Remember to be in the moment and look for the beauty in life.  Get back to the core fundamentals.  [1:13:33] Keep Testing Yourself  Not everyone can do everything at the same time. Therefore, doctors need to help people prioritise what will work for them.  Charles shares that he's very proud of Care Oncology's work in cancer treatment.  Despite being 63, he likes to climb mountains annually to challenge himself.  Charles details how he puts himself in uncomfortable situations in the full episode. [1:19:21] Future of Medicine Charles shares that the next ten years may change many things in medicine.  Look into the research. Clinical practice is often behind the latest developments.  Stay persistent and take care of yourself. Twenty years ago, people would die one year after losing their vitality and independence. Now, they tend to live up to 12 years. They may be alive, but they're often unhappy.  7 Powerful Quotes.' 'A healthy person has multiple wishes and ideas while a sick person only has one wish — that's to get better again. Early spending of the dedication of time and money pays off.' 'A lower dose metabolic protocol with prescription drugs and supplements, and lifestyle coaching prevent the development of disease or cancer.' 'If you find cancer in stage one, you have a greater than 90% cure, which is surgery at most. Then if you find it in stage four, the cure rate drops down to the mid-teens, then you're never off treatment, and you will spend a fortune.' '...to eat anything. That is the worst advice that you can give a cancer patient.'   "We're evolutionarily designed to eat primarily fats and proteins with some seasonal carbohydrates. So that's what 99% of our biology was based on.' 'Sometimes, an ounce of prevention could save you financially and, actually, health.' 'A lot of times, there's a silver lining to some of these obstacles put in our way.' Resources Gain exclusive access and bonuses to Pushing the Limits Podcast by becoming a patron!  Tripping Over the Truth: How the Metabolic Theory of Cancer Is Overturning One of Medicine's Most Entrenched Paradigms by Travis Christofferson  Curable: How an Unlikely Group of Radical Innovators is Trying to Transform our Health Care System by Travis Christofferson  How to Starve Cancer by Jane McLelland Listen to our previous episodes:  Episode 229: Cancer Treatments: Starve Cancer, Be Free From It with Jane McLelland Episode 227: Fighting Cancer and Other Diseases Using The Ketogenic Diet with Dr Dominic D'Agostino   Care Oncology: Website I Facebook  AVRT Now Connect with Dr Charles: LinkedIn  Want to learn more from Dr Charles? Check out Coach it Forward Chuck   About Dr Charles Dr Charles Meakin is the US Medical Director at Care Oncology Clinic with over 40 years of experience in healthcare, eastern philosophies, fitness predictors of longevity, and happiness. In 2018, he retired after 30 years in radiation oncology practice due to a worsening retinal condition. He then joined Care Oncology and launched his charity health and wellness coaching.  Want to learn more about Charles? Check out Care Oncology and Coach it Forward, Chuck.  You can also find him on LinkedIn.    Enjoyed This Podcast? If you did, subscribe and share it with your friends! Post a review and share it! If you enjoyed tuning in, then leave us a review. You can also share this with your family and friends so they can know how to prevent diseases like cancer. If you have any other queries, you can contact me through email (support@lisatamati.com) or find me on Facebook, Twitter, LinkedIn, and YouTube. For more episode updates, visit my website. You may also tune in on Apple Podcasts. To pushing the limits, Lisa.

Arthritis is a severe disease that's uncomfortable at best and debilitating at worst. It is a leading cause of disability worldwide. Most people think that arthritis only happens to the elderly, but it can affect anyone. It is a disease that begins in your 20s or results from injuries sustained as a child. Unfortunately, most of what the general public is misinformed about arthritis: what it is, how it starts, and how to treat it! In this episode, Dr Elizabeth Yurth addresses common misconceptions about arthritis. She defines the disease and offers realistic alternatives to established treatment options. If you want to learn more about longevity-based proactive measures to address arthritis, this episode is for you! Here are three reasons why you should listen to the full episode: Recognise arthritis as an inflammatory process rather than a wear-and-tear disease. Understand the importance of addressing arthritis early on — as early as your 20s! Learn how longevity studies-based supplements and treatments improve the immune system and combat arthritis. Get Customised Guidance for Your Genetic Make-Up For our epigenetics health programme, all about optimising your fitness, lifestyle, nutrition and mind performance to your particular genes, go to  https://www.lisatamati.com/page/epigenetics-and-health-coaching/. Customised Online Coaching for Runners CUSTOMISED RUN COACHING PLANS — How to Run Faster, Be Stronger, Run Longer  Without Burnout & Injuries Have you struggled to fit in training in your busy life? Maybe you don't know where to start, or perhaps you have done a few races but keep having motivation or injury troubles? Do you want to beat last year's time or finish at the front of the pack? Want to run your first 5-km or run a 100-miler? ​​Do you want a holistic programme that is personalised & customised to your ability, goals, and lifestyle?  Go to www.runninghotcoaching.com for our online run training coaching. Health Optimisation and Life Coaching Are you struggling with a health issue and need people who look outside the square and are connected to some of the greatest science and health minds in the world? Then reach out to us at support@lisatamati.com, we can jump on a call to see if we are a good fit for you. If you have a big challenge ahead, are dealing with adversity or want to take your performance to the next level and want to learn how to increase your mental toughness, emotional resilience, foundational health, and more, contact us at support@lisatamati.com. Order My Books My latest book Relentless chronicles the inspiring journey about how my mother and I defied the odds after an aneurysm left my mum Isobel with massive brain damage at age 74. The medical professionals told me there was absolutely no hope of any quality of life again. Still, I used every mindset tool, years of research and incredible tenacity to prove them wrong and bring my mother back to full health within three years. Get your copy here: https://shop.lisatamati.com/collections/books/products/relentless. For my other two best-selling books Running Hot and Running to Extremes, chronicling my ultrarunning adventures and expeditions all around the world, go to https://shop.lisatamati.com/collections/books. Lisa's Anti-Ageing and Longevity Supplements  NMN: Nicotinamide Mononucleotide, an NAD+ precursor Feel Healthier and Younger* Researchers have found that Nicotinamide Adenine Dinucleotide or NAD+, a master regulator of metabolism and a molecule essential for the functionality of all human cells, is being dramatically decreased over time. What is NMN? NMN Bio offers a cutting edge Vitamin B3 derivative named NMN (beta Nicotinamide Mononucleotide) that can boost the levels of NAD+ in muscle tissue and liver. Take charge of your energy levels, focus, metabolism and overall health so you can live a happy, fulfilling life. Founded by scientists, NMN Bio offers supplements of the highest purity and rigorously tested by an independent, third-party lab. Start your cellular rejuvenation journey today. Support Your Healthy Ageing We offer powerful third-party tested NAD+ boosting supplements so you can start your healthy ageing journey today. Shop now: https://nmnbio.nz/collections/all NMN (beta Nicotinamide Mononucleotide) 250mg | 30 capsules NMN (beta Nicotinamide Mononucleotide) 500mg | 30 capsules 6 Bottles | NMN (beta Nicotinamide Mononucleotide) 250mg | 30 Capsules 6 Bottles | NMN (beta Nicotinamide Mononucleotide) 500mg | 30 Capsules Quality You Can Trust — NMN Our premium range of anti-ageing nutraceuticals (supplements that combine Mother Nature with cutting edge science) combats the effects of aging while designed to boost NAD+ levels. Manufactured in an ISO9001 certified facility Boost Your NAD+ Levels — Healthy Ageing: Redefined Cellular Health Energy & Focus Bone Density Skin Elasticity DNA Repair Cardiovascular Health Brain Health  Metabolic Health My  ‘Fierce' Sports Jewellery Collection For my gorgeous and inspiring sports jewellery collection, 'Fierce', go to https://shop.lisatamati.com/collections/lisa-tamati-bespoke-jewellery-collection. Episode Highlights [03:30] Breaking the Misconceptions about Arthritis Arthritis is more than a wear-and-tear condition; it's an inflammatory disease process.  It is not limited to the elderly. The disease process can begin with minor injuries, even those sustained as a child. Arthritis is a combination of genetics and environmental factors triggered by trauma.  [08:25] Arthritis as an Inflammatory Disease Process   Arthritis is a disease process like neurodegenerative and cardiac illnesses.  Our bodies follow a balanced way to deal with injuries. It releases the level of cytokines that set off the body's response to healing and recovery. Afterwards, cytokine levels fall, and anti-inflammatory proteins take over. The disease process begins during Imbalance in any part of the process. It can be started as too many cytokines lead to zombie cells and lack of autophagy. [12:20] General Approaches to Addressing Arthritis  Turn off inflammatory cytokines through simple supplements like curcumin or epigallocatechin.  Turning down the inflammatory response allows the injury to heal better.  Inducing autophagy or knocking off the bad cells helps reduce injury as well.  [13:36]  Arthritis is a Preventable Disease  Arthritis is a disease that should be given more attention, as it has a significant impact on people's quality of life. It is the primary cause of disability among people of working age.  Arthritis is preventable to a large degree, despite genetics and other factors.  [18:32] Current Orthopedic Treatments for Arthritis  The focus in addressing arthritis is to treat the disease process. Steroid injections temporarily reduce inflammatory cytokines, but they also inhibit those that aid in healing. Arthroscopic surgery can provide immediate comfort. However, it can also inflict tears that can cause the rapid progression of arthritis. Back fusion can help cases of spinal instability. However, for degenerative discs, the long-term success rate of surgery is around 10% of those who undergo it. [24:09]  Degenerative Disc Disease as an Inflammatory Disease  Degenerative disc disease is an inflammatory disease caused by high levels of cytokines. This includes the nuclear factor kappa beta. The goal is to focus on the issues that cause disc destruction, such as elevated cytokine levels, rather than the disc itself. Ageing processes, like degeneration, should serve as a wake-up call to reconsider one's diet. This also includes reconsidering supplements, and exercise, as well as one's cardiovascular health. [27:18]  Changing the Perspective about Arthritis People should be aware that arthritis begins in their 20s, similar to brain disorders, heart ailments, and cancers.    All these immune and inflammatory diseases come down to curing ageing.  We need to take proactive steps and opt for longevity instead of a mechanical standard of care.  Opting for the ‘expensive' care earlier will save you time, stress, and money. People often exhaust traditional options first before pursuing longevity treatments.  [38:49] Pentosan Polysulfate: ‘A Cure for Arthritis' Pentosan polysulfate is a repurposed drug that reduces cytokines causing degenerative disc pain.  According to studies, even after just six weeks of using Pentosan Polysulfate, you can continue to reap the advantages for up to a year. [45:07] Vitamins and Supplements to Combat Arthritis  Another strategy to fight arthritis is to make sure your nutrients are optimised. Vitamins D and C, and zinc are critical but straightforward micronutrients. Epigallocatechin gallate, or EGCG, has many benefits that aid in addressing arthritis. Its benefits include muscle-building, fat loss, and myostatin blocking. [47:07] Benefits of Gaining Muscle Muscle, as an organ, produces endocrine glands, and myokines have very beneficial effects on joints.   Those with sarcopenia or muscle loss are more likely to develop joint arthritis. Electrical stimulation of muscles can be done for individuals who are further along in a disease process. Static contraction or contracting the muscles for three seconds every hour also helps muscle-building.  [51:03]  Inducing Autophagy Process Using Spermidine  Spermidine is a polyamine compound that comes from bacteria in certain foods.  Polyamine is produced by the human body as well. However, as we become older, we make less of it. It is an autophagy-Inducing agent that aids in getting rid of damaged cells.  Spermidine works better than steroids at reducing inflammation. It preserves the joints without making them worse. [54:06] Trehalose: The ‘Sugar Substitute' Trehalose is glucose that impacts oxidative stress and helps clean up the cells.  It has zero glycemic impact, which helps blood glucose under control.  Trehalose is looked at for neurodegenerative diseases but can benefit joint pain.  [56:57] Peptide Therapies as Simple, Inexpensive Aid  If you are looking for simple, inexpensive aid, collagen peptides can also be beneficial.  They typically are part of a mixture including Vitamin C, which helps cartilage cells.  A more expensive option is aggressive peptides, like BPC 157 or Body Protection Compound 157. These peptides can aid joint regeneration. It's vital to understand the role of inflammation in arthritis rather than jumping at treatments, like stem cell therapy. [59:54] The Role of Stressed Immune System  Almost every disease is related to over-aggressive, pro-inflammatory cytokines, disruption in mitochondrial function, and autophagy.  Ageing causes a significant number of diseases.  The immune system goes awry for many reasons, including viral exposures. [59:54] Antiviral Drugs, Hormones, and Fasting Antiviral drugs, hormones, and fasting can help the immune system fight diseases as healthy as possible.  EGCG and curcumin are natural compounds that have some antiviral properties. Acyclovir is also a safe choice for combatting the herpes virus and Epstein-Barr, among others.   Our immune system produces fewer hormones as we become older. Our bodies need hormones to function, so we need to replace them somehow. Hormones have huge immune-modulating properties that help stop oxidative stress.  The immune system benefits from the recovery period following a fast. It can be very beneficial to clear out dead cells. [1:08:55] Rapamycin and Metformin: The ‘Future' of Arthritis Rapamycin is a chemotherapeutic medication with a solid immune-modulating effect.  It is well-known for activating autophagy, which can lengthen lifespan in all mammalian species scientists have studied. Metformin is an inexpensive medication that keeps glucose control.  It has some interesting studies on arthritis. One study shows the overlapping benefits in cardiovascular, renal, cancer, and obesity protection.  7 Powerful Quotes “[Arthritis as an inflammatory disease process] is the same thing that goes on with COVID. Right? Yes. Why do some people die of COVID? [It's] usually not the virus itself -- it's the immune reaction to the virus.”   “So we know we have to treat [cytokines] and not the disc itself. That's the end game. Treat the problem that's causing the disc damage.”   “...[W]e're really trying to get into the heads of these [20-year-olds] and say, the [disease process starts when you're] 20. Yeah, like your brain diseases, your heart diseases, and your cancers are all those processes are starting in our 20s.”   “The plastic surgeons are doing fine. [P]eople are more than willing to spend that money on their facelifts and things like that [than] internally to feel better.”   “You can have no cartilage and no pain or no discs, and no gain. The pain is an inflammatory sign.” “Go back, go back up the tree. And then you had all of the diseases in mitochondria and information.” "Be it cancer, metabolic disease, cardiovascular disease, or neurologic arthritis, they're all the same disease. You've got to get the immune system as healthy as possible. You have to stop oxidative stress." Resources Gain exclusive access and bonuses to Pushing the Limits Podcast by becoming a patron!  Track your blood glucose in real-time with Levels Health.  Tripping Over the Truth: How the Metabolic Theory of Cancer Is Overturning One of Medicine's Most Entrenched Paradigms by Travis Christofferson  Curable: How an Unlikely Group of Radical Innovators is Trying to Transform our Health Care System by Travis Christofferson  How to Starve Cancer by Jane McLelland Want to learn more from Dr Dom? Check out Peter Attia's podcast episodes with him:  Episode 116 - AMA with Dom D'Agostino, PhD, Part I of II: Ketogenic diet, exogenous ketones, and exercise Episode 120 – AMA with Dom D'Agostino, PhD, Part II of II: Ketosis for cancer and chronic disease, hyperbaric oxygen therapy, and the effect of ketosis on female health  Episode 5 - Dom D'Agostino, PhD: ketosis, n=1, exogenous ketones, HBOT, seizures, and cancer       You can also check out other podcasts where Dr Dom was a guest here.  The 1-Week and 8-Month Effects of a Ketogenic Diet or Ketone Salt Supplementation on Multi-Organ Markers of Oxidative Stress and Mitochondrial Function in Rats  Press-pulse: a novel therapeutic strategy for the metabolic management of cancer  Ketone supplementation decreases tumour cell viability and prolongs the survival of mice with metastatic cancer  Moffitt Cancer Center  Get your exogenous ketones from Audacious Nutrition  Keto Nutrition: Website | Youtube | Instagram | Facebook Connect with Dr Dom: Twitter | LinkedIn | Instagram About Dr Elizabeth Dr Elizabeth Yurth, MD, FAARFM, ABAARM is a practising orthopedic. She specialises in sports, spine, and regenerative medicine and has over 25 years of professional experience as a practising orthopaedic physician. She is a double-Board Certified in Physical Medicine & Rehabilitation and Anti-Aging/Regenerative Medicine.  Dr Yurth has dedicated her life to longevity. In 2006, she founded the Boulder Longevity Institute, where she serves as the Medical Director. She has worked as the team physician for Stanford and Santa Clara Universities and consulted for the San Francisco 49ers and the San Jose Ballet. Dr Yurth has a dual-Fellowship in Anti-Aging and Regenerative Medicine (FAARM), and Anti-Aging, Regenerative and Functional Medicine (FAARFM) through the American Academy of Anti-Aging Medicine (A4M). She recently completed a Fellowship in Human Potential and Epigenetic Medicine.  You can learn more and connect with Dr Elizabeth on Twitter, LinkedIn, and Instagram. Enjoyed This Podcast? If you did, be sure to subscribe and share it with your friends! Post a review and share it! If you enjoyed tuning in, then leave us a review. You can also share this with your family and friends so they can know how to optimise sleep.  Have any questions? You can contact me through email (support@lisatamati.com) or find me on Facebook, Twitter, Instagram and YouTube. For more episode updates, visit my website. You may also tune in on Apple Podcasts. To pushing the limits, Lisa  

Most of the time on Chat the Fat, we talk about how to use Keto, Low Carb or intermittent fasting for weight loss results. Today we have a story that is all about using Keto for recovery. So many go into keto for the weight loss benefits they'll receive, and they end up sticking with their keto plan because of all of the amazing health benefits that come with following a real food keto diet.  Today I'm chatting with Heather Cooan, who overcame a serious health diagnosis with using a ketogenic diet as part of her healing protocol. Heather is a marketing executive turned nutrition counselor, consultant, and educator. Heather is currently a Nutrition Therapist Master and Functional Diagnostic Nutrition Practitioner candidate and advocates for informed consent, bodily autonomy, and self-directed healthcare. She speaks and writes on nutrition and lifestyle interventions for improved health and wellness. Heather successfully avoided radiation and chemotherapy and healed her body of vulvar cancer utilizing a food-as-medicine approach combined with conventional interventions such as surgery. Heather has also put two autoimmune diseases into remission (Hashimotos and Lichen Sclerosus) and reversed estrogen dominance, insulin resistance, hardening of the arteries, and fatty liver through diet and lifestyle change. Links Mentioned: HeatherCooan.Com Heather's Detailed Story Heather's Treatment Plan Books on The Metabolic Theory of Cancer  Instagram @heathercooan Twitter @heathercooan  

In this episode we have the pleasure of talking with science writer Travis Christofferson. We begin by discussing the emerging paradigm of Cancer as a Metabolic disease, and how this new approach can overturn, or build on top of, the discoveries we have achieved while approaching cancer as a genetic disease. We also talk about the importance of “outsiders” coming into specific fields and the need for empathic and trust-building narratives to support cross-disciplinary collaboration. We talk about the emerging possibilities of blending human agency and intuition with the power of statistics and machines, the importance of “mindset” to utilize stress instead of being used by it, and a few other things on the science of longevity. Travis Christofferson has a degree in molecular biology and a master's degree in material engineering and science. He is a full-time science writer and published the best selling book Tripping Over the Truth which shows how the Metabolic Theory of Cancer is overturning one of Medicine's most entrenched paradigms. He is the founder of The Foundation for Metabolic Cancer Therapies, and the co-founder of Care Oncology. Sígueme en: Instagram: https://www.instagram.com/v_saadia Suscríbete a mi newsletter: https://victorsaadia.substack.com/?sh... Conoce mis cursos: https://www.victorsaadia.com/cursos Conoce mis libros: https://www.victorsaadia.com/libros

What role does metabolism play in cancer? Is cancer driven by DNA errors or sick mitochondria? Which is causal? Today we discuss this with Maggie and Brad Jones. After Maggie was diagnosed with terminal cancer with a prognosis of less than a year, she dedicated herself to a new, healing lifestyle. Instead of dying, she is cancer free years out. She is now a certified nutritionist and cancer coach advocating the same nutrition, metabolic and lifestyle therapies that saved her life. Maggie and Brad are producing a new documentary on the science behind the metabolic theory of cancer with leading experts in the field: CancerEvolution.  Here is the special offer they mention.  For just $25 you get the movie the minute it is released and your pre-payment goes to help fund the graphics and editing efforts to get it all finished.https://www.indiegogo.com/projects/cancerevolution-a-cancer-science-documentary?secret_perk_token=b9dabefc#/ Only available to our audience: a digital copy of the film as soon as it's available and instant access to our digital poster, custom music, and an exclusive 5-minute clip.Included Items* Our deepest gratitude* Digital Poster* Digital Soundtrack* Digital Director's cut of filmEstimated Shipping September 2022Documentary Clips: https://www.youtube.com/cancerevolutiondoc Website: https://cancerevolution-movie.com/ Maggie's personal site: https://cancerv.me/ Documentary: https://cancerevolution-movie.com/ https://www.youtube.com/cancerevolutiondoc/ https://www.instagram.com/cancerevolutiondoc/ https://facebook.com/cancerevolutiondoc/https://twitter.com/CancerEvolves Maggie: https://cancerv.me/https://www.instagram.com/mostlyveganketo/ https://www.facebook.com/cancerVme #longevity #wellness  #Ketones #lifestylemedicine #cancer #ketosis #biohacking #acetone #RobertLufkinMD #cancerevolution  #maggieandbradJones #metabolictheorycancer***Rapamycin Longevity Registry***https://www.rapamycin.io/*** CONNECT WITH ROBERT LUFKIN MD ON SOCIAL MEDIA ***Web: https://robertlufkinmd.com/ Twitter:https://twitter.com/robertlufkinmdYoutube: https://www.youtube.com/RobertLufkinMD*** GOT A SUGGESTION FOR A SHOW? ***Contact us at: https://robertlufkinmd.com/contact *** SPONSORSHIPS & BRANDS ***We do work with sponsors and brands. If you are interested in working with us for your health industry product or service, please contact us at: https://robertlufkinmd.com/contact  NOTE: This is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have. Never disregard professional medical advice or delay in seeking it because of something you have seen here. Robert Lufkin MD may at any time and at its sole discretion change or replace the information available on this channel. To the extent permitted by mandatory law, Robert Lufkin MD shall not be liable for any direct, incidental, consequential, indirect or punitive damages arising out of access to or use of any content available on this channel, including viruses, regardless of the accuracy or completeness of any such content.Disclaimer: We are ambassadors or affiliates for many of the brands we reference on the channel.Support the show

Even the most resilient and strongest individuals are not safe from the bone-deep exhaustion that cancer can bring. Treatment protocols will vary depending on a patient's condition, but they may cause fatigue. While it takes an average of 17 years for medical research to reach clinical practice, it is beyond doubt that there are now better ways to treat cancer. Did you know there is now emerging evidence that a ketogenic diet combined with standard cancer treatment may help patients? We often hear about the ketogenic diet from the fitness industry, but it's more than just for managing weight, glucose and insulin levels. Research shows it can also starve cancer cells and eventually kill them off!  In this episode, Dr Dominic D'Agostino discusses how the ketogenic diet has evolved and how we can adopt a proper ratio for our lifestyle. He also shares the press-pulse control to manage cancer, which includes utilising ketosis, Vitamin C and oxygen. Don't wait until you're diagnosed with a disease to become more mindful of your lifestyle and nutrition! Prevention is key if you want to live healthier. If you want to learn more about fighting cancer and several other diseases through the ketogenic diet, then this episode is for you! Here are three reasons why you should listen to the full episode: Understand how exogenous ketones and the ketogenic diet can help make your cells more resilient and even combat cancer! Remember that we need to prioritise preventing diseases. Starting early is key.  Learn how cancer cells function and how to kill them without suffering from side effects common from drugs. Get Customised Guidance for Your Genetic Make-Up For our epigenetics health programme, all about optimising your fitness, lifestyle, nutrition and mind performance to your particular genes, go to  https://www.lisatamati.com/page/epigenetics-and-health-coaching/. Customised Online Coaching for Runners CUSTOMISED RUN COACHING PLANS — How to Run Faster, Be Stronger, Run Longer  Without Burnout & Injuries Have you struggled to fit in training in your busy life? Maybe you don't know where to start, or perhaps you have done a few races but keep having motivation or injury troubles? Do you want to beat last year's time or finish at the front of the pack? Want to run your first 5-km or run a 100-miler? ​​Do you want a holistic programme that is personalised & customised to your ability, goals, and lifestyle?  Go to www.runninghotcoaching.com for our online run training coaching. Health Optimisation and Life Coaching Are you struggling with a health issue and need people who look outside the square and are connected to some of the greatest science and health minds in the world? Then reach out to us at support@lisatamati.com, we can jump on a call to see if we are a good fit for you. If you have a big challenge ahead, are dealing with adversity or want to take your performance to the next level and want to learn how to increase your mental toughness, emotional resilience, foundational health, and more, contact us at support@lisatamati.com. Order My Books My latest book Relentless chronicles the inspiring journey about how my mother and I defied the odds after an aneurysm left my mum Isobel with massive brain damage at age 74. The medical professionals told me there was absolutely no hope of any quality of life again. Still, I used every mindset tool, years of research and incredible tenacity to prove them wrong and bring my mother back to full health within three years. Get your copy here: https://shop.lisatamati.com/collections/books/products/relentless. For my other two best-selling books Running Hot and Running to Extremes, chronicling my ultrarunning adventures and expeditions all around the world, go to https://shop.lisatamati.com/collections/books. Lisa's Anti-Ageing and Longevity Supplements  NMN: Nicotinamide Mononucleotide, an NAD+ precursor Feel Healthier and Younger* Researchers have found that Nicotinamide Adenine Dinucleotide or NAD+, a master regulator of metabolism and a molecule essential for the functionality of all human cells, is being dramatically decreased over time. What is NMN? NMN Bio offers a cutting edge Vitamin B3 derivative named NMN (beta Nicotinamide Mononucleotide) that can boost the levels of NAD+ in muscle tissue and liver. Take charge of your energy levels, focus, metabolism and overall health so you can live a happy, fulfilling life. Founded by scientists, NMN Bio offers supplements of the highest purity and rigorously tested by an independent, third-party lab. Start your cellular rejuvenation journey today. Support Your Healthy Ageing We offer powerful third-party tested NAD+ boosting supplements so you can start your healthy ageing journey today. Shop now: https://nmnbio.nz/collections/all NMN (beta Nicotinamide Mononucleotide) 250mg | 30 capsules NMN (beta Nicotinamide Mononucleotide) 500mg | 30 capsules 6 Bottles | NMN (beta Nicotinamide Mononucleotide) 250mg | 30 Capsules 6 Bottles | NMN (beta Nicotinamide Mononucleotide) 500mg | 30 Capsules Quality You Can Trust — NMN Our premium range of anti-ageing nutraceuticals (supplements that combine Mother Nature with cutting edge science) combats the effects of aging while designed to boost NAD+ levels. Manufactured in an ISO9001 certified facility Boost Your NAD+ Levels — Healthy Ageing: Redefined Cellular Health Energy & Focus Bone Density Skin Elasticity DNA Repair Cardiovascular Health Brain Health  Metabolic Health My  ‘Fierce' Sports Jewellery Collection For my gorgeous and inspiring sports jewellery collection, 'Fierce', go to https://shop.lisatamati.com/collections/lisa-tamati-bespoke-jewellery-collection. Episode Highlights [03:40] Dr Dom's Background Dr Dom majored in nutrition science and biology, then studied neuroscience for his PhD. Specifically, he studied the neural control of our physiology through electrophysiology. This includes respiratory and cardiovascular controls. His research interests then led him to study diving physiology and hyperbaric technologies. For over 15 years, Dr Dom has been developing hyperbaric technologies and nutritional and supplemental therapies to protect people from high hyperbaric conditions.  [06:14] How to Make Cells More Resilient Dr Dom shares that electrophysiology in hyperbaric chambers can directly measure neurons in response to the graded levels of oxygen in the chamber.  Oxygen can provide a therapeutic effect, but too much of it can lead to a seizure (oxygen toxicity). His research on measuring the cellular response on the level of mitochondria and plasma membrane led him to study how to control the metabolic states of the cell to make them more resilient to extreme environments.  Dr Dom worked with the NAVY Seal divers and focused on treatments such as lactate, glucose and ketones to enhance cell metabolic states and reduce seizures.  Ketones can not only make cells more resilient but also help maintain resting membrane potential and have less oxidative stress. [12:07] How the Ketogenic Diet has Evolved  The ketogenic diet is celebrating its 100th year anniversary in clinical use. It started as a standard of care for drug-resistant epilepsy in children. Anti-epileptic drugs have been found to delay learning development in kids, while the diet can enhance development. The ketogenic diet has also evolved over the years. The modified Atkins diet, or MADD, utilises a 20–25% protein diet.  The quantity and type of fat are important when considering a ketogenic diet. Listen to the full episode to learn more!  Over the years, research on the ketogenic diet and its applications have surged. Now, Dom is working with the Navy to not only use ketones to block seizures, but to also enhance performance. [18:56] What is the Ketogenic Diet for?   There are two primary uses for the ketogenic diet: life-saving and prevention.  If your intent is to manage seizure disorders, neurological disorders, cancers,and other disorders, you need to implement a ketogenic diet continuously.  Using the ketogenic diet for prevention can be for controlling glucose and insulin levels. It's better to prevent disorders and diseases by getting ahead of the problem.  For example, those who are pre-diabetic should start monitoring their glucose levels and learn how to eat better to avoid becoming diabetic. [23:13] Prioritise Prevention Diabetes can be the gateway to a host of other diseases. Prevention is key. The ketogenic diet can be very effective in controlling your glucose and insulin levels. When tracking your glucose levels, don't focus on single time points. Instead, observe how the levels change over time. Understand the dynamic of glucose in your body. You can correlate them with changes in inflammatory markers. You can check whether you're in ketosis through biomarkers that can be measured through breath, blood or urine ketones. [27:26] How to Adopt the Ketogenic Diet to Your Lifestyle The ketogenic diet is four parts fat and one part combination of protein and carbohydrates.  This means around 90% fat, 8 to 10% protein, and around 10 grams of fibrous carbohydrates. This is the recommended diet used for pediatric epilepsy.  You can also modify the diet if you find it too strict and difficult to follow. Ketones have been found to be anti-inflammatory, neuroprotective, and have epigenetic effects. [29:23] Managing Cancer Through the Ketogenic Diet  It's not enough to cut down on sugar. Cancer cells are metabolically flexible and can use other sources like glutamine, fatty acids, and more.  Studies show that if you take away glucose from cancer cells and give them ketones, they will eventually die.  Cancer patients will experience the Warburg effect, where cells revert to a primitive form of energy metabolism by directing biomolecules to anabolic processes.  However, this also allows cancer cells to grow, divide and expand.  Treating cancer can be done by blocking DNA replication like chemotherapy or by energy restriction. While you cannot fast forever, you can achieve the fasting state through a ketogenic diet. [38:33] Utilise Autophagy to Kill Cancer Cells  Cancer cells naturally have higher energy demand than healthy cells. When you restrict energy, you can stimulate autophagy, slowing down tumour growth and eventually killing it.  There may be forms of cancer that can capitalise on autophagy, but this is not common.   [43:55] How to Use Vitamin C to Combat Cancer Glucose monitors tend to also detect Vitamin C as blood sugar since they are very similar.  However, ascorbic acid can be antagonistic to glucose by using the same transporter. When you have high physiological levels of Vitamin C, you can impair glucose metabolism in cancer cells.   Vitamin C can also help create the Fenton Effect, where it further increases oxidative stress in tumours.  [49:42] How Much Oxygen Is Enough for Cancer Cells?  Cancer cells can die when exposed to a rise in oxygen.  Dr Dom shares that his study used a 2.5 atmosphere of oxygen given for 60 minutes three days a week. This was done using a soft-shell chamber.  Lower levels of oxygen can still be beneficial for cell production.  Dr Dom recommends taking Vitamin C on the same day as getting hyperbaric oxygen therapy.  [55:29] What to Remember When You Have Cancer Nutrition should be the core of general health and cancer therapy.  Restrict sugar, optimize glycemic control and suppress insulin. Do intermittent fasting if you can.  If you're overweight, be more aggressive with fasting and the ketogenic diet. If you're underweight, make sure you have enough protein and nutrients. Dr Dom recommends foods like eggs, sardines, raw vegetables like salads, olive oil, nuts and non-glycemic fibrous carbohydrates.  He also recommends taking exogenous ketones to further boost ketosis.  [1:02:53] Types of Exogenous Ketones   MCT is useful for fat and ketone. You can also use ketone salts which are bound to electrolytes like sodium, calcium, potassium and magnesium.  Racemic compounds optimise signalling and delivery pathways.  You don't want spikes in your glucose and ketones.  Listen to the full episode to learn more! [1:09:08] Dr Dom's Recommendations Dr Dom has always been interested in fitness. Not only is he interested in the science of nutrition, but he also applies it to himself.  Our bodies can withstand fasting. The more you do it, the easier it gets, and you'll get more benefits.  Remember to take care of your body.    7 Powerful Quotes ‘Oxygen is a stimulant to the brain, and if we get too high, it can actually trigger a seizure.'   ‘...some of the anti-epileptic drugs, if they are given to kids, they can cause developmental delays. Whereas if you administer a ketogenic diet, it actually enhances learning and memory.'   ‘We believe that it's very important if you're pre-diabetic, to get different wearable technologies that will tell you and coach you how to eat so you don't become diabetic.'   ‘Warburg hypothesized that the cells were producing, were fermenting because the mitochondria were damaged, and they were defaulting to a more primitive form of energy production.'   ‘The ketogenic diet is mimicking fasting and I think that the suppression of the hormone insulin, the reduction in glucose availability, and the elevation of ketones are all contributing to the anti-cancer effect.'   ‘...nutrition is really about the patient's health and they should not be advised to just eat anything to gain weight.'   ‘I think it's important to push the limit as well. I mean, I was always interested in fitness, and working out, strength training has been a form of self-medication.' Resources Gain exclusive access and bonuses to Pushing the Limits Podcast by becoming a patron!  Track your blood glucose in real time with Levels Health.  Tripping Over the Truth: How the Metabolic Theory of Cancer is Overturning One of Medicine's Most Entrenched Paradigms by Travis Christofferson  Curable: How an Unlikely Group of Radical Innovators is Trying to Transform our Health Care System by Travis Christofferson  How to Starve Cancer by Jane McLelland Want to learn more from Dr Dom? Check out Peter Attia's podcast episodes with him:  Episode 116 - AMA with Dom D'Agostino, PhD, Part I of II: Ketogenic diet, exogenous ketones, and exercise Episode 120 – AMA with Dom D'Agostino, PhD, Part II of II: Ketosis for cancer and chronic disease, hyperbaric oxygen therapy, and the effect of ketosis on female health  Episode 5 - Dom D'Agostino, Ph.D.: ketosis, n=1, exogenous ketones, HBOT, seizures, and cancer       You can also check out other podcasts where Dr Dom was a guest here.  The 1-Week and 8-Month Effects of a Ketogenic Diet or Ketone Salt Supplementation on Multi-Organ Markers of Oxidative Stress and Mitochondrial Function in Rats  Press-pulse: a novel therapeutic strategy for the metabolic management of cancer  Ketone supplementation decreases tumor cell viability and prolongs survival of mice with metastatic cancer  Moffitt Cancer Center  Get your exogenous ketones from Audacious Nutrition  Keto Nutrition: Website | Youtube | Instagram | Facebook Connect with Dr Dom: Twitter | LinkedIn | Instagram About Dr Dom Dr Dominic D'Agostino is currently an associate professor with tenure at the University of South Florida where he teaches in the Morsani College of Medicine and the Department of Molecular Pharmacology and Physiology. He focuses on topics such as neuropharmacology, medical biochemistry, physiology, neuroscience, and neuropharmacology. He is also a research scientist at the Institute for Human and Machine Cognition (IHMC) where he researches optimization of safety, health, and resilience of astronauts and warfighters. Over the last decade, Dr Dom and his lab have been focused on understanding the ketogenic diet and ketone supplementation for anticonvulsant and neuroprotective benefits. He was also a research investigator and crew member on NASA's Extreme Environment Mission Operation (NEEMO 22) and has an interest in ways to enhance resilience in extreme environments.  Learn more about Dr Dom's work on his website.  You can also connect with him on Twitter, LinkedIn, and Instagram. Enjoyed This Podcast? If you did, be sure to subscribe and share it with your friends! Post a review and share it! If you enjoyed tuning in, then leave us a review. You can also share this with your family and friends so they can know how to optimise sleep.  Have any questions? You can contact me through email (support@lisatamati.com) or find me on Facebook, Twitter, Instagram and YouTube. For more episode updates, visit my website. You may also tune in on Apple Podcasts. To pushing the limits, Lisa   The information contained in this show is not medical advice it is for educational purposes only and the opinions of guests are not the views of the show. Please seed your own medical advice from a registered medical professional.  

We actually are filming a bit more for the Food Lies documentary in a few weeks at a great ranch in Oklahoma. I can't stress enough the lengths we are going to to make this the absolute best film possible. We need a mic-dropper, jaw-dropper, kale shake dropping film. ANything less won't work. It won't reach the mainstream. It won't reach Joe Cheeto out in Ohio. It won't reach the vegan in the coffee shop with the soy latte in Santa Monica. It won't reach the hilarious jokesters at the Harvard Chan School of Public Health with their comical EAT Lancet funded diet for planetary health with more added sugar and 3x the seed oils than meat. Well it probably will never reach those bought and paid for fake scientists anyway. But we are going to make it that good where someone there might watch it and realize they're living a lie and will quit their Kellogg's and Coca-cola funded position. Really interesting new paradigm on how the heart works and how atherosclerosis and other problems developed based on a bunch of research he's looked at. I don't think anyone's put it together like this before in one model like he's done. Very intriguing stuff. He attained both his Doctorate of Chiropractic and Masters in Human Nutrition and Functional Medicine from the University of Western States in Portland, OR. He is a health coach, speaker, and the author of two books on health; The Health Evolution: Why Understanding Evolution is the Key to Vibrant Health and The Heart: Our Most Medically Misunderstood Organ. Dr. Hussey guides clients from around the world back to health by using the latest research and health attaining strategies Get the best meat around at http://nosetotail.org Only 3 lifetime memberships left at http://sapien.org Special price on the program at http://sapien.org GET THE MEAT! http://NosetoTail.org GET THE FREE SAPIEN FOOD GUIDE! http://Sapien.org   SHOW NOTES [8:35] His background. [14:30] His past involving Type 1 Diabetes and poor metabolic health.  [17:45] A brief history on the evolution of mitochondria.  [21:10] The Metabolic Theory of Cancer.  [23:40] The Autonomic Nervous System.  [34:00] Chronic stress and the issues it can create.  [39:45] Anatomy and physiology of the heart and how blood flows. [52:45] The 4th phase of water.  [56:15] Free radicals.  [59:30] How to mitigate excessive free radicals/oxidative stress.  [1:06:00] How the heart reacts to clots and ruptures.  [1:09:00] The surprising benefits of LDL and cholesterol.  [1:12:10] Angiogenesis of the heart and surrounding arteries. [1:16:45] Main interventions to prevent heart disease. [1:18:30] Different ways we can get heart attacks. [1:20:20] His own experience with a heart attack and western medicine.   GET THE MEAT! http://NosetoTail.org GET THE FREE SAPIEN FOOD GUIDE! http://Sapien.org   Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg  

I quickly go over some research I have been doing on the metabolic theory of cancer. I dont know all the answers, but I wanted to put this out there in case anyone out there was out of time and needed some hope. [[ This is a content summary only. Visit my website for full links, other content, and more! ]]

I quickly go over some research I have been doing on the metabolic theory of cancer. I dont know all the answers, but I wanted to put this out there in case anyone out there was out of time and needed some hope. [[ This is a content summary only. Visit my website for full links, other content, and more! ]]

 Catherine Wreford Ledlow is an accomplished artist having performed at the Stratford Festival at the age of 18 as part of West Side Story and The Tempest. Freddie and Catherine talk about brain cancer and how she got through the obstacles that surrounded her daily life. This episode takes us into Catherine's story and how much her life has changed ever since she was diagnosed. If you want to learn more about Catherine's life, the daunting effect of brain cancer on the patient and their loved ones, or you just want to hear something inspiring and thought-provoking then you can't miss this out! HIGHLIGHTS2:29 Freddie and Catherine talk about brain cancer and how she noticed the signs before the actual diagnosis.15:18 Dealing with children isn't easy and Catherine shares how a proper support system helped her power through her diagnosis.19:16 What type of brain cancer does Catherine have? She also discusses the kinds of chemotherapy that she has had to go through.20:37 Catherine explains the prognosis given to her, the chemotherapy treatments that she has gone through, and going through a life-changing surgery.24:45 The doctors gave Catherine four choices post-surgery in order to move forward.30:36 Catherine shares the different alternatives that she has come across her journey towards her recovery.33:54 Freddie and Catherine discuss how treatments and alternatives are effective but keeping your mindset and emotions in check is also important.36:03 As the conversation continues, Freddie and Catherine further discuss the importance of keeping your diet in control.41:43 Catherine talks about her family and how the people around you can help you throughout whatever you're currently struggling in.47:30 Freddie and Catherine discuss the huge impact that cancer has on everyone and that early detection is a big must in order to try and curb its mortality rate.49:49 Catherine talks about being open about her brain cancer and finding something to laugh about despite it.54:09 Freddie and Catherine talk about using Optune to help battle cancer cells.57:24 As the episode comes to an end Freddie and Catherine discuss the opportunities that may come next.     RESOURCES MENTIONED Tripping over the Truth: How the Metabolic Theory of Cancer is Overturning One of Medicine's Most Entrenched Paradigms by Travis Christofferson - https://www.amazon.com/Tripping-over-Truth-Overturning-Entrenched/dp/1603587292Optune - https://www.optune.com/  UPGRADE YOUR WELLNESSActivate your Stem Cells - LifeWave.com/beautifullybrokenBuy Red Lights for Wellness - Lightpathled.com - Discount Code - beautifullybrokenMicrobiome Labs probiotics - https://microbiomelabs.com - Checkout Code - FreddiesetgoAmpCoil and PEMF - Discount Code - BeautifullyBroken   CONNECT WITH FREDDIECheck out my website - https://freddiesetgo.com/ Instagram - https://www.instagram.com/freddiesetgo/Read my Favs - https://freddiesetgo.com/freddies-favorites/ Sing For Your Seniors - https://http://singforyourseniors.org Amp Coil - https://www.ampcoil.com ABOUT FREDDIE I'm Freddie Kimmel, a Functional Health Coach, Reiki Healer, Certified Personal Trainer, Gut Health Specialist, and a proud cancer survivor. I help men and women eliminate brain fog, bloat and belly fat through gut health. I've been featured in The Wall Street Journal, the Full Plate Podcast, An Excellent Example of Being Human, State of the Arts on LA talk radio and Dance Magazine. I have a Bachelor of Fine Arts from SUNY Brockport, attended SUNY Fredonia, and graduated from the Institute of Functional Health Coaching. I can be found in NYC living each day to its fullest and focused on creating more value than what I capture. Please stand back from the awesomeness that's about to unfold.

Most of the time on Chat the Fat, we talk about how to use Keto, Low Carb or intermittent fasting for weight loss results. Today we have a story that is all about using Keto for recovery. So many go into keto for the weight loss benefits they’ll receive, and they end up sticking with their keto plan because of all of the amazing health benefits that come with following a real food keto diet.  Today I’m chatting with Heather Cooan, who overcame a serious health diagnosis with using a ketogenic diet as part of her healing protocol. Heather is a marketing executive turned nutrition counselor, consultant, and educator. Heather is currently a Nutrition Therapist Master and Functional Diagnostic Nutrition Practitioner candidate and advocates for informed consent, bodily autonomy, and self-directed healthcare. She speaks and writes on nutrition and lifestyle interventions for improved health and wellness. Heather successfully avoided radiation and chemotherapy and healed her body of vulvar cancer utilizing a food-as-medicine approach combined with conventional interventions such as surgery. Heather has also put two autoimmune diseases into remission (Hashimotos and Lichen Sclerosus) and reversed estrogen dominance, insulin resistance, hardening of the arteries, and fatty liver through diet and lifestyle change. Links Mentioned: HeatherCooan.Com Heather’s Detailed Story Heather’s Treatment Plan Books on The Metabolic Theory of Cancer  Instagram @heathercooan Twitter @heathercooan  

In this ninth episode, Travis Christofferson provides an overview of his new future of medicine book “Curable: How an Unlikely Group of Radical Innovators is Trying to Transform our Health Care System”. Read the transcript He covers the great inefficiencies of healthcare and harm it’s doing to swaths of the patient population. He explains it’s too qualitative than quantitative, that incentives are misaligned. He offers hope by urging a shift to being data-driven. Topics we discussed in this episode The economics of Moneyball Data can overcome our cognitive biases Repurposing medications Metformin Huge disparities and variations of treatment Veneration of a physician’s intuition has and still causes great harm Complexity of medicine has outstripped the human mind ability to do it effectively Fee for service model incentivizes unnecessary treatments Prescribed medications are third largest cause of death globally 30% to 50% of all healthcare dispensed is over treatment Doctors on salary change the way they practice medicine, aligning with patient more Precision pre-operation antibiotic timing Easily saving thousands of lives saved and billions of dollars The need to get to the source of disease and use a preventative type of medicine Unnecessary cancer treatment with early detection The need to focus on wellness and lifestyle things like diet Metformin and berberine Going all the way disease upstream and tackling aging itself Resveratrol Interventions like ketogenic diet and fasting show great data, but no incentives due to lack of financial rewards Most expensive treatments typically done even when there is no data to indicate that they are more effective Healthcare is a parasite dragging down American business on the world stage Amazon, JP Morgan and Berkshire Hathaway building their own healthcare from the inside out Virta Health as an example of an emerging innovative boutique health system Variation in treatment is not something that’s taught in medical school Healthcare is disassociated from the way capital markets traditionally work End of life chemotherapy and other aggressive treatments are evil Lack of government investment in research to treat disease at source, the aging process itself Water fasting before chemotherapy Epigenetics Our health is nowhere near as deterministic as we used to think just twenty years ago Show links Tripping over the Truth: How the Metabolic Theory of Cancer Is Overturning One of Medicine's Most Entrenched Paradigms by Travis Christofferson (Book) Curable: How an Unlikely Group of Radical Innovators is Trying to Transform our Health Care System by Travis Christofferson (Book) Moneyball: The Art of Winning an Unfair Game by Michael Lewis (Book) Care Oncology UK (Website) Care Oncology USA (Website) Metformin (Wikipedia Entry) Radical mastectomy (Wikipedia Entry) Sapiens DS’ Brad Perkins on a new healthcare industry emerging from computing (Previous Episode transcript) Nudge: Improving Decisions About Health, Wealth, and Happiness by Richard Thaler (Book) An American Sickness: How Healthcare Became Big Business and How You Can Take It Back by Elisabeth Rosenthal (Book) Intermountain Healthcare (Website) Brent James MD (LinkedIn Profile) Hacking the Software for Life by Brad Perkins (Conference talk video) The Price We Pay: What Broke American Health Care and How to Fix It by Marty Makary MD (Book) Metformin and berberine, two versatile drugs in treatment of common metabolic diseases (Paper) Lifespan: Why We Age and Why We Don't Have To by David Sinclair PhD (Book) Overkill: An avalanche of unnecessary medical care is harming patients physically and financially. What can we do about it? by Atul Gawande (New Yorker, Article) Virta Health (Website) Substantial health and economic returns from delayed aging may warrant a new focus f...

A lot of people have given up hope in the medical industry due to ineffective and costly treatments, especially when it comes to cancer. That is why many people are now finding alternatives and have found new benefits through naturopathic and holistic approaches to fighting off this disease. In this episode, Dr. Wolfson is joined by naturopathic physician Dr. Donese Warden. They introduce and explain the metabolic theory of cancer and how new research into this disease is leading to new ways of treatment.

Dr. Nasha Winters is a sought-after luminary and a global healthcare authority in integrative cancer research and consults with physicians around the world. She bridges ancient therapies with advancements in modern medicine in the digital era. Dr. Nasha consults with some of the most prestigious cancer centers in the US on projects such as developing the clinical protocol for the current FDA-approved clinical trial using intravenous application of Viscum Album Extract (mistletoe) to treat advanced cancer. She has educated approximately 250 professionals in the clinical use of mistletoe and has created robust educational programs for both healthcare institutions and the public on incorporating vetted integrative therapies in cancer care to enhance outcomes.  She comes on The Elevate Your State Show today to shine a bright light on WHAT cancer really is, HOW it works, and WHAT some of the more effective therapies look like in our modern-day world. A personal journey with cancer, overseeing care of tens of thousands of patients worldwide, and training practitioners in her methodology underscores her passion and purpose to be a beacon of hope for thousands. Dr. Nasha is on a mission to educate and empower the nearly fifty percent of the population expected to have cancer in their lifetime. Prevention is the only cure. To learn more about her work go to www.drnasha.com.    Show Notes: 1:20 - her weekly morning breakfast -- FASTING 3:07 - her personal journey and passion for cancer 16:50 - what mitochondria is and how it affects our health and body 18:49 - otto warburg effect 20:44 - what are the main focuses with the somatic theory of cancer and where has it fallen short 25:53 - cancer prevention and healing hacks 36:01 - nutrition’s impact on cancer 47:17 - good go-to healthy fats 54:10 - why she doesn’t use 23 and me 57:45 - the endocannabinoid system and how it relates to healing 1:04:49 - Dr. Nasha Winters tiered approach   Links: Quantum Healing - Deepak Chopra's book The Otto Warburg Effect The Somatic Theory of Cancer vs. Metabolic Theory of Cancer Tripping Over the Truth - Great book on cancer. Dr. Nasha Winters’ book, The Metabolic Approach to Cancer What is Apoptosis? What is Epigenetics? Alex Swanson & Nutrition Genome Pili Nut - Hunter Gatherer Foods EndoCannaHealth.com EAD Labs/BioCBD Episode with James Radina, founder of BioCBD/EAD Labs The Metabolic Approach to Cancer - Facebook page DrNasha.com Quotes: 21:08 - “Our [cancer] survival outcomes have changed very little since the 1950s” 23:33 - “The terrain…the communication between the cells…the medium in which those cell are brewing in… is actually where disease and health begin.” 26:56 - “When we are in health, we are respiring, we are breathing, properly” 32:59 - “You cannot heal the body from the soil in which the disease grew.” 1:08:23 - “We are very responsive to other people’s energies, and I find that when I surround myself with people who vibrate at a high vibe energy it pushes me to do the same.”

What's the ultimate cause of cancer? It's not an easy question to answer, and according to Travis Christofferson, author of Tripping Over the Truth: The Return of the Metabolic Theory of Cancer, there's no single cause, but a series of complex interactions and events that depend at least somewhat on our environment. Christofferson explains this in terms of epigenetic responses, which result in the turning off or on of certain genes--allowing some to be expressed and blocking others from being expressed. Diet, toxins, medications, and even loneliness are just a few of the factors that could trigger epigenetic responses and ultimately contribute to the determination of whether or not someone will develop cancer. Christofferson offers an insightful conversation that touches on a range of topics, including the benefits of using metabolic therapy in conjunction with chemotherapy and radiation, the therapeutical differential between cancer cells and healthy cells that's produced by the ketogenic diet, the use of aerobic glycolysis by cancer cells as opposed to oxidative pathways (the Warburg effect) and how this can be taken advantage of in the treatment of cancer, how and why the repurposing of drugs--in particular Metformin--holds promise as a form of cancer treatment, and why brain cancers seem to be most responsive to metabolic therapies.  Click play to hear the full conversation, and check out his book to learn more. 

Joining us today is Dr. Anthony Jay, scientist, author, and expert on a wealth of topics including xenoestrogens, epigenetics, and mesenchymal stem cells. Ben and Dr. Jay dive deep on how to remove artificial estrogens from your environment and diet and the effects of xenoestrogens. We also discuss how you can impact your genetics through diet, exercise and environment as well as the implications of your epigenetics on future generations. Lastly we discuss Dr. Jay’s latest research at the Mayo Clinic on fat derived mesenchymal stem cells and his thoughts on the future of stem cell medicine. The MI 40 Nation is putting on a Transformation Challenge for the next 12 weeks! We are giving away over $10,000 in cash and prizes. Sign up at bit.ly/mi40transformation to be entered for the 4 week contests and to win the grand prize! This episode’s featured supplement from ATP Labs is Estro Control. This 100% natural formula helps to detox estrogens and support a healthy estrogen metabolism. Visit atplab.com/product/estro-control/ to purchase Estro Control and use code Ben10 for 10% off of your order Time Stamps: 4:20- The effects of artificial estrogens on our bodies and minds. 6:30- Dr. Jay’s list of the top 10 environmental contributors of environmental estrogens including mold sources, plastics, and personal care products. 8:20- Atrazine and your food. The effects of the second most common pesticide on your hormones. 9:50- How to avoid xenoestrogens. 11:50- Detoxing estrogens. The importance of a healthy lifestyle to support estrogen detoxing. 13:20- The difference between natural and artificial estrogen. 17:50- Epigenetics and diet. How your diet can effect your genes for generations to come. 22:00- How to determine your optimal diet from your genes. 25:15- Genetics and estrogen detox. How much can Dr. Jay learn from your DNA about how you detox estrogens? 29:00- Recommendations for reducing the estrogen burden in your house, whole house filtration, glass containers and more. 31:30- Red dyes and your epigenetics. How Red 40 can alter your stem cells and change the genetics you pass along to your children. 38:30- Ways to promote healthy epigenetics. 42:00- How Dr. Jay lives his greatest life in his greatest body. 44:30- Reading List! Dr. Jay’s must reads. 47:00- Who is best suited to eat a high fat diet? 50:15- Dr. Jay and ketosis. What diet does Dr. Jay follow and why. 52:50- Dr. Jay’s latest research at the Mayo Clinic. The efficacy of stem cell therapy in Dr. Jay’s eyes. 56:30- The challenges that face stem cell research and expansion. Resources: Dr. Jay’s favorite books- Stem Cell Therapy: A Rising Tide: How Stem Cells Are Disrupting Medicine and Transforming Lives by Neil Riordan Tripping over the Truth: How the Metabolic Theory of Cancer Is Overturning One of Medicine's Most Entrenched Paradigms by Travis Christofferson Fat for Fuel: A Revolutionary Diet to Combat Cancer, Boost Brain Power, and Increase Your Energy by Dr. Joseph Mercola Multipure Water Filtration- https://www.multipure.com/products.html

Welcome to the Wealthy Wellthy Life with Krisstina Wise. On this new series on cancer, Krisstina speaks with Travis Christofferson, author of Tripping Over the Truth: How the Metabolic Theory of Cancer Is Overturning One of Medicine’s Most Entrenched Paradigms. In this conversation, Travis explains alternative treatments to cancer such as the Ketogenic Diet and Hyperberic Oxygen therapy, the metabolic theory of cancer and why there is such resistance against it, and offers advice on what you can do if you or a loved one is diagnosed with cancer. For full show notes visit: http://wealthywellthy.life/cancer1

Thomas Seyfried is Professor of Biology at Boston College where his research is exploring new alternative methods of treating and managing chronic diseases such as epilepsy and cancer. He wrote the groundbreaking treatise, “Cancer as a Metabolic Disease: on the Origin, Management and Prevention of Cancer”, and he joins us today to discuss non-toxic ways to treat, manage and prevent disease. Guest: Connect with Thomas Seyfried by reading his book Cancer as a Metabolic Disease: on the Origin, Management and Prevention of Cancer and be sure to watch his talks on Youtube and follow him on the Twitters, @tnseyfried Show Notes: • Tripping over the Truth: How the Metabolic Theory of Cancer Is Overturning One of Medicine's Most Entrenched Paradigms • Cancer as a Metabolic Disease: on the Origin, Management and Prevention of Cancer • United States incarceration rate • Glutamine: A novel approach to chemotherapy-induced toxicity • Could a Change in Diet Cure Your Dog’s Cancer? • Single Cause Single Cure

Travis Chistofferson is on the show to make sure we understand exactly what the metabolic theory of cancer is and why it is so vitally important in preventing and reversing cancer.  Travis’ book Tripping over the Truth was basically written for the exact purpose of taking Professor Thomas Seyfreid’s (episode 006) book Cancer as a Metabolic Disease which is more of a textbook converting it into something easier for the public to digest and give more of the backstory which is why it’s the very first book I recommend to anyone that really wants to understand cancer and how we got to where we are today.   In This Episode:   The metabolic theory of cancer itself and why it’s so important for anyone going through cancer to understand. How cancer cells can actually turn back into healthy cells when if their metabolism is able to be corrected or if not how they can be weakened and killed off altogether with this approach.  The best dietary strategies and best known therapeutic interventions such as the ketogenic diet and oxidative therapies. Travis’s thoughts on the success of approaches such as the Gerson Therapy which are high in sugars and antioxidants. The history of modern cancer treatment going back to Otto Warburg who first put this viewpoint out there back in the mid 1900’s and how it is that we’ve managed to get so wrapped up genes and really miss the forest for the trees. Epigenetics and how we should look at them in light of the metabolic theory of cancer.   For more cancer healing and preventing: www.mykidcurescancer.com www.youtube.com/mykidcurescancer www.facebook.com/mykidcurescancer   To support our work: www.mykidcurescancer.com/crowdsponsor    Travis Christofferson is a graduate of the Montana State Honors Program in molecular biology. He received the Nelson Fellowship for "outstanding undergraduate research", and continued graduate research in bioremediation and cancer theory culminating in an M.S. in Material Engineering and Science from the South Dakota School of Mines and Technology.***   He is a science writer and the author of the book Tripping Over the Truth: The Metabolic Theory of Cancer. The book offers a historical perspective on the reemerging metabolic theory of cancer -- a theory that contends cancer is precipitated and driven by damage to mitochondria.

This year in the United States, over 22,000 people will be diagnosed with a primary brain or spinal tumor. Of these, more than 13,000, many of them younger than 21 years old, will die of their disease. New treatment modalities are critical in the battle against cancer. Adrienne Scheck, PhD, is an associate professor of neurobiology at Barrow Neurological Institute. Dr. Scheck’s expertise includes neuro-oncology. She is a member of the American Association for Cancer Research, Society for Neuro-Oncology, American Association for Cancer Research, American Society for Biochemistry and Molecular Biology, Women in Cancer Research, and the American Association for the Advancement of Science. Dr. Scheck’s work consists mainly of translational research to develop novel adjuvant therapies for the treatment of brain tumors. She also use various molecular and molecular genetic techniques to investigate why current therapies sometimes fail.   See Scheck AC[Author] on PubMed. Here’s the outline of this interview with Dr. Adrienne Scheck: [00:00:37] Dr. Jong M Rho. [00:01:18] Glioblastoma. [00:03:53] Hanahan, Douglas, and Robert A. Weinberg. "Hallmarks of cancer: the next generation." cell 144.5 (2011): 646-674. [00:05:01] Cancer metabolism: see Tripping Over the Truth: The Return of the Metabolic Theory of Cancer Illuminates a New and Hopeful Path to a Cure. [00:05:37] Positron emission tomography (PET). [00:06:20] Thomas Seyfried: Cancer: A Metabolic Disease With Metabolic Solutions. [00:07:21] Adding ketones to a in vitro model. [00:09:14] Poff, Angela M., et al. "The ketogenic diet and hyperbaric oxygen therapy prolong survival in mice with systemic metastatic cancer." PloS one 8.6 (2013): e65522. [00:11:38] 4:1 KetoCal. [00:13:14] Dr. Cate Shanahan at the Keto Summit. [00:15:05] Ketogenic Diet With Radiation and Chemotherapy for Newly Diagnosed Glioblastoma. [00:17:08] Charlie Foundation and Matthew's Friends. [00:21:42] Clinical trial diet is as close to 4:1 as possible. [00:22:09] Ketogenic Mealplanner – Electronic Ketogenic Manager (EKM). [00:23:01] Cachexia. [00:24:09] Ketones of 3mM, glucose of 4mM. [00:25:59] Adrienne gave a talk in Banff but I couldn’t find it online. [00:26:23] Trial eligibility. [00:30:29] Confounding lifestyle factors. [00:32:58] MRI for tumor metabolism . [00:34:25] Is there something special about brain tumors that makes them particularly susceptible? [00:35:25] Dominic D'Agostino on my podcast and the Keto Summit. [00:35:48] Edema, angiogenesis, and inflammation. [00:37:36] Lussier, Danielle M., et al. "Enhanced immunity in a mouse model of malignant glioma is mediated by a therapeutic ketogenic diet." BMC cancer16.1 (2016): 1. [00:40:14] Gut microbiome. [00:41:50] Ketone supplementation. [00:47:54] Effects in cancer patients may be different from in a healthy person. [00:48:45] Students Supporting Brain Tumor Research. [00:50:35] MaxLove Project. [00:50:47] Donations. [00:52:28] Finding a physician and a dietician. [00:55:13] Education for dietitians and practitioners. [00:57:51] Pluripotency. [00:58:55] Adam Sorenson and father Brad.

Cancer is like a computer program gone wrong, the kernel panic of the human body. Unfortunately, we have no reboot button, and so cancer is the most serious of diseases. This year, almost six hundred thousand Americans will die from cancer. Despite the fact that cancer receives more NIH funding than any other illness, the death rates remain the same as in the 1950s. Tripping Over the Truth: The Return of the Metabolic Theory of Cancer tells the story of molecular biologist and science writer Travis Christofferson’s journey to discover why cancer has remained so elusive. The central theme of the book is that we’ve fundamentally mischaracterized the origin of cancer. Most scientists hold to the belief that cancer is a genetic disease, Travis explores the idea that cancer is, in fact, a disease of damaged metabolism. The metabolic theory of cancer stems from Nobel laureate Otto Warburg’s observation in 1924 that cancer cells lack the ability to produce energy using anything other than an ancient and inefficient process of fermentation. Warburg’s idea failed to gain critical mass, and by the 1960s had largely faded into oblivion. In 2012, Thomas Siegfried, Ph.D., released his book Cancer as a Metabolic Disease where he expanded on Warburg’s original hypothesis. In his book, Siegfried described how all cancer cells have damaged mitochondria, the organelle responsible for creating energy with oxygen. Inspired by The Emperor of All Maladies by Siddhartha Mukherjee, Travis has done a excellent job of telling the rich story behind the metabolic theory of cancer. In this interview, Travis and I discuss some of the potential benefits and mechanisms of a ketogenic diet, hyperbaric oxygen, gluconeogenesis inhibitors and ketone supplements as possible cancer therapy. I would like to thank Dr. Tommy Wood for some of the questions asked in this interview, especially those about glioblastoma and women with the BRCA1 mutation and breast cancer. Here’s the outline of this interview with Travis Christofferson: 0:00:15    Book: Tripping Over the Truth: The Return of the Metabolic Theory of Cancer Illuminates a New and Hopeful Path to a Cure 0:00:34    How Travis became in terested in biology. 0:00:54    Travis has a fundamental curiosity. 0:01:10    The best doctors are the ones that do experiments on themselves. 0:01:22    Book: Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer by Tom Siegfried. 0:01:38    Book: The Emperor of All Maladies: A Biography of Cancer by Siddhartha Mukherjee. 0:02:16    Travis wanted to tell the rich story behind the science in Tom's book. 0:03:01    Podcast: Dominic D'Agostino on the Tim Ferriss show. 0:03:30    The Emperor is gene centric. 0:03:46    The difference between the genetic and metabolic theories of cancer. 0:04:08    Radiation, cell repair. 0:04:09    In the genetic theory, cancer arises through lesions on DNA. 0:04:43    The genetic theory is still the dominant theory. 0:04:55    In the metabolic theory, cancer is proliferated by damage to the mitochondria. 0:05:07    Cancer resorts to less efficient fermentation. 0:05:25    This less efficient metabolism sends a message to the DNA. 0:05:42    This new theory makes cancer look like a disease of order. 0:06:02    Everything that causes cancer damages mitochondria. 0:06:39    Paul Davies, cosmologist. 0:07:07    Worked with Stephen Hawking. 0:07:33    Video: Anna Barker at TEDMED 2010. 0:07:53    Cancer is incredibly complex compared to other diseases. 0:08:19    In 2008 atavistic model 0:08:48    Three million studies on cancer on PubMed. 0:09:20    In the beginning, there was single celled organisms. 0:09:26    With multicellular life, the rules changed. 0:09:43    The foetal genes are reexpressed in cancer. 0:10:03    This new understanding gives hope. 0:10:17    What can we do with this new knowledge. 0:10:28    Look after our mitochondria. 0:10:38    A ketogenic diet is a great way to achieve this. 0:10:48    Also intermittent fasting. 0:10:57    Metformin as an oncology drug. 0:11:20    Exploiting the express of early genes. 0:11:44    The Warburg Effect. 0:11:53    Hyperbaric oxygen. 0:12:01    Cancer cells decouple of the adaptive immune system. 0:12:07    Cancer patients with high fever then spontaneous remission. 0:12:25    Cancer cannot withstand infection. 0:12:56    How does the ketogenic diet work against cancer? 0:13:04    Lowering blood glucose. 0:13:11    Glucose is the preferred fuel of cancer. 0:13:25    Some cancers can utilise ketones. 0:13:45    But there's promise in all cancers. 0:14:05    There's some kind of signalling mechanism. 0:14:27    Less side-effects with chemo after fasting. 0:15:05    Dr. Tommy Wood pointed me at some studies showing that certain breast cancers can use ketones as fuel. One study of women with the BRCA1 mutation showed that those with upregulated ketone metabolism did worse, which suggests that a cancer can develop metabolic flexibility too, and would be able to avoid death on a ketogenic diet. 0:15:27    Everybody is different and your results therefore will vary. 0:15:51    The brain can obtain up to 80% of its energy requirenents from ketones. 0:16:09    Some neurons are too small to include a mitochondria. 0:16:21    There is a trial going on in Arizona with glioblastoma. 0:16:25    Dr. Adrienne C. Scheck. 0:16:29    Results by April. 0:16:41    Kid in Norway, prognosis is 8 months, that was 3 years ago. 0:17:12    Tumor has shrunk and remained stable now for 3 years. 0:17:31    Metabolic therapies are good at managing cancer, but may not be the cure. 0:17:55    The studies are all done from the same line of glioblastoma. 0:18:17    Glioblastoma is where the research started, but the principle is sound 0:18:41    Will glioblastoma be the first cancer that we see a cure for? 0:18:48    Glioblastoma is usually about a year from the time of diagnosis to death. 0:19:17    How do cancers show up in a PET scanner? 0:19:24    PET scanners detect radiolabeled glucose. 0:19:43    The tumour outcompetes normal cells for glucose and show they show up in the scanner. 0:20:25    If the tumours have been lighting up in scanners for a long time, why has it taken so long for anyone to think of this? 0:20:41    Dr. Scheck’s study is using a standard ketogenic diet. 0:20:43    In some people that doesn't drive down glucose very far. 0:21:06    You can drive blood glucose very low. 0:21:21    In extended fasts, blood glucose would go down in the 60s (mg/dL). 0:21:24    Now we have exogenous ketone supplementation. 0:21:27    And gluconeogenesis inhibitors. 0:22:50    What were gluconeogenesis inhibitors originally designed for? 0:23:05    We're only just starting to appreciate Metformin. 0:23:06    25-30% reduction in the chances of getting cancer on Metformin. 0:23:07    Nobody really knows how is works. 0:23:31    Phenylbutyrate. 0:23:55    Metformin also inhibits complex 1 of the ETC. 0:24:07    ROS are bad, but also signalling molecules. 0:24:23    Another line of research has shown that Metformin works through altering the gut microbiome. 0:24:44    Podcast: Exercise is an antioxidant. 0:25:02    Podcast: Tommy and me on the Robb Wolf podcast. 0:25:11    Podcast: Insulin resistance. 0:25:15    Podcast: Iron overload. 0:25:46    In biology, you focus on one thing. One protein, one pathway. 0:25:55    Dr. Coe? in Travis's book. 0:25:56    ATPase. 0:26:15    You need someone to do the detailed work, but then you need someone to step back. 0:26:30    Physics already has a mechanism in place to do that. 0:27:05    In physics, you can come up with an idea and there's more than enough data to test it out. 0:27:31    Worse, in nutrition the data conflicts each other. 0:27:33    The NCI said that 80% of the basic research in cancer biology were not reproducible. 0:27:56    Sorting through the studies is an art form. 0:28:08    Warren Buffett. 0:28:22    What do you think of the meta-analysis? 0:28:53    This is the Gold Standard of science! 0:29:11    Book: Good Calories, Bad Calories: Fats, Carbs, and the Controversial Science of Diet and Health by Gary Taubes 0:30:36    Ketone supplements are not currently be used in cancer therapy. 0:31:09    Dominic D'Agostino specialises in ketone supplementation. 0:31:34    Ketones are far more than a macronutrient. 0:31:49    Ketones are anti-inflammatory. 0:32:08    Seasonal ketosis. 0:32:22    Dr. Veech at the NIH: "it's not normal to have a McDonald’s on every street corner". 0:32:30    It's normal to starve periodically. 0:32:53    Alzheimer's is now being called type 3 diabetes. 0:33:41    Is it a good idea to be constantly in ketosis? 0:33:58    Dr. Peter Attia. 0:34:32    Two studies, one at the National Institute of Aging, one at the University of Wisconson 0:34:37    Caloric restriction in monkeys. 0:34:49    Caloric restriction doesn't help as much as we thought. 0:35:02    The monkeys fed a high-sugar diet did worse. 0:35:27    When is all this going to be more widely know, or even the standard of care? 0:35:40    Things move slowly, it's easy to get depressed. 0:35:57    The trial in Arizona could be groundbreaking. 0:36:34    3-Bromopyruvate (3BP) could be the final piece for the metabolic therapy. 0:37:05    Heroin as the treatment for cocaine addiction. 0:37:47    Radical mastectomy. 0:38:25    This went on for 80 years. 0:38:37    In the end, we discovered that a local lumpectomy was as effective. 0:38:58    The trials are so slow and expensive. 0:39:16    You have to eat something, why not this?. 0:39:42    Travis talked at Paleo f(x). 0:39:57    Anecdotally, word is getting out there. 0:40:24    The ketogenic diet to treat recurrence. 0:40:37    The ketogenic diet is empowering. 0:41:11    Travis wrote an article about recurrence on his website. 0:41:20    It's not about always about a single cell that got left behind. 0:41:36    20% of cases are new, i.e. the environment for cancer is still there. 0:42:09    The same is true of bacteria, if you create the environment, it will grow. 0:42:25    Nobody wants to take high-fat diets seriously for weight loss until we're talking about cancer. 0:42:48    Cachexia is the the worst case scenario. 0:43:40    Valter Longo, PhD. 0:44:21    The state of ketosis doesn't say anything about weight loss, and may even be protective against muscle wasting. 0:44:42    Travis and Dominic's articles on Robb Wolf's website. 0:45:41    The Charlie Foundation. 0:46:04    Travis's new blog with podcast, Metabolic Optimization. 0:46:43    Dominic holds the Guinness World record for the most weight squatted in 24 hours (he broke the record in six). 0:47:15    Travis is a fulltime author.