Podcasts about aids

This is a free preview of a paid episode. To hear more, visit andrewsullivan.substack.comEmily is a senior editor at the New York Times Book Review. She's also worked as a senior editor at The New Yorker, an ideas reporter for the NYT, a fashion features writer at Vogue, and a deputy editor of Lingua Franca magazine. Her new book is The Frenchmen: Or, My Life in Theory.A polished transcript is here, including money quotes. Below are timestamps for the main sections of the pod:* 03:56: Emily's upbringing in a Francophile family* 14:27: The postmodern idea that language is everything* 31:05: The postmodern New Right* 41:14: The dark dysfunctional lives of many of the French thinkers* 103:27: The fatalism in pomo discourse* 117:14: How Emily became skeptical of postmodernismFor two clips of the episode — on the word games of postmodernists, and the screwed-up lives of Foucault and others — head to our YouTube page.More topics: Emily growing up in Indiana with regular trips to France; the country's post-war boom but drop in world status; colonial revolt in Algeria; Heidegger and Nazism; Barthes and Maoism; Derrida and language; Levi-Strauss and structuralism; Camus and existentialism; nihilism; bourgeois as an epithet; Lacan and the unconscious; Althusser strangling his wife to death; the Straussian cult; Allan Bloom; the Sokal hoax; Stanley Fish and deconstruction; John Boswell and homosexuality; Foucault deconstructing gayness; the AIDS crisis; the prison system; Orwell and Oakeshott; Sarah Bakewell on Montaigne; HR and pronouns; the fatalism of Coates; and Trump's exec orders on language in government.Browse the Dishcast archive for an episode you might enjoy. Coming up: Michael Lewis on the bureaucrats who fought back against Trump, Evan Barker on how the Democratic Party got hijacked by elite activists, Sean Illing on the relevance of Camus and Nietzsche, Catherine Conybeare on Augustine, and Cyrus Habib on leaving politics to become a Jesuit priest. Please send any guest recs, dissents, and other comments to dish@andrewsullivan.com.

Russell T Davies has spent decades creating some of Britain's most beloved and groundbreaking television. After studying English at Oxford, he went from writing for children's programmes and Coronation Street to creating Queer As Folk in 1999 - a show that changed the conversation around gay representation on TV. Since then, he's written hit after hit, from Bob & Rose and A Very English Scandal to Years and Years, It's A Sin and his hugely successful revival of Doctor Who. He's won four BAFTAs and was awarded an OBE in 2008. In this episode we talk about where his obsession and passion for TV came from, how his exceptionally busy mind works, losing his husband to a brain tumour, his love of Dr Who and…finding love again. His new memoir, The Queerest of Folk, is out on 8th October. IN THIS EPISODE: 00:00 Intro 02:35 TV Obsession Origins 03:24 Memoir and Andrew 08:35 AIDS and Its a Sin 10:36 Queer as Folk Shockwaves 12:37 Failure to Drive 16:45 Writing in Images 28:05 Early Illustration Gigs 28:54 Obsessed With Drawing 30:20 Losing the Habit 31:52 Comics and Story Beats 33:54 Writing Geniuses Doctor Who 37:13 Staying a Fan 41:41 Legacy and Family Roots 49:59 Aging Love and Goodbye

In this episode of the Explaining History Podcast, we are joined by historian Peter Parker to discuss the remarkable rediscovery of James Courage's A Way of Love – widely regarded as the first gay novel by a New Zealander – and what it tells us about gay life in post-war Britain.First published in 1959 and banned in New Zealand in 1961, A Way of Love has returned to print after nearly seven decades. Set in 1950s London, it follows two men attempting to build a life together at a time when sex between men remained a criminal offence. Its timing is significant: it appeared two years after the Wolfenden Report recommended that homosexual acts between consenting adults in private should no longer be criminalised, but eight years before the partial decriminalisation introduced by the Sexual Offences Act of 1967.Peter Parker, author of Some Men in London volumes one and two – acclaimed anthologies of gay life in the capital – joins us to explore this fascinating transitional moment. Drawing on James Courage's extraordinary diary as well as the novel, we examine what it meant to be a gay man in a society where prosecution, censorship and social stigma were constant threats.We discuss the geography of gay life – the private members' clubs and pubs where men could relax and be amongst their own people – and the language they used, including the secret argot of Polari. We also explore the long struggle for legal reform, the resistance of the Metropolitan Police, and the cultural shifts that helped change attitudes – from the pioneering work of the Homosexual Law Reform Society to the impact of films like Victim (1961) and John Osborne's A Patriot for Me.Peter also reflects on the "happy ever after" problem in gay history: the assumption that rights appeared by magic overnight, rather than being won through decades of struggle, persecution and sacrifice.Topics covered:James Courage, A Way of Love, and its suppression and rediscoveryThe criminalisation of homosexuality and the Wolfenden ReportThe policing of gay life and the "pretty police"Gay clubs, pubs, and cultures of solidarityPolari and coded languageThe Homosexual Law Reform Society and the fight for legal changeVictim, A Patriot for Me, and stage censorshipThe pushback of AIDS and Clause 28Memory, martyrdom, and the unfinished struggle for equalityPeter Parker's Some Men in London volumes one and two are available from all good bookshops. James Courage's A Way of Love is republished by Lyric Editions. Please consider buying from an independent retailer or directly from the publisher.If you enjoy the podcast, please consider supporting us – we are migrating from Patreon to Substack. Details in the show notes.This response is AI-generated and for reference purposes only.Explaining History helps you understand the 20th Century through critical conversations and expert interviews. We connect the past to the present. If you enjoy the show, please subscribe and share.▸ Support the Show & Get Exclusive ContentBecome a Patron: patreon.com/explaininghistory▸ Join the Community & Continue the ConversationFacebook Group: facebook.com/groups/ExplainingHistoryPodcastSubstack: theexplaininghistorypodcast.substack.com▸ Read Articles & Go DeeperWebsite: explaininghistory.org Hosted on Acast. See acast.com/privacy for more information.

In Deutschland nehmen sich jedes Jahr mehr als 10.000 Menschen das Leben. Die Zahl der Suizidversuche liegt Schätzungen zufolge zehn- bis zwanzigmal höher. Damit sterben mehr Menschen durch Suizid als durch Verkehrsunfälle, Gewalttaten, illegale Drogen und AIDS zusammen. Jeder Suizid hinterlässt Spuren: Neuere Zahlen gehen von bis zu 135 Menschen aus, die direkt oder indirekt betroffen sind, darunter Familie, Freundinnen und Kolleginnen. In dieser Folge von caritalks spricht Christoph Grätz mit drei Menschen, die sich beruflich und ehrenamtlich dafür einsetzen, Menschen in suizidalen Krisen beizustehen: • Chantal Abt, Leiterin des Teams Suizidprävention bei der Caritas Gelsenkirchen • Selin Yazicioglu, hauptamtliche Mitarbeiterin von [U25], der Mailberatung für junge Menschen mit Suizidgedanken • Michael Denzin vom Förderverein der TelefonSeelsorge Essen Die drei berichten aus ihrer Arbeit: Woran erkennt man, dass jemand an Suizid denkt? Wie können Angehörige, Freund*innen oder Kolleg*innen darauf reagieren? Und wie schützen sich die Berater*innen selbst in dieser zum Teil belastenden Arbeit? Zum Schluss formulieren sie ihre Wünsche an die Gesellschaft, das Thema Suizid offener anzusprechen, und an die Politik, diese wichtige Arbeit verlässlich zu unterstützen. Anlass für das Gespräch war der Welttag der Suizidprävention am 10. September. Am Vorabend fand in der Essener Marktkirche ein Gedenkgottesdienst statt, an dem alle drei Gäste mitgewirkt haben. Hilfe in Krisen: Wenn du selbst an Suizid denkst oder dir Sorgen um jemanden machst, bist du nicht allein. Die TelefonSeelsorge ist rund um die Uhr kostenfrei und anonym erreichbar unter 0800 111 0 111 und 0800 111 0 222 sowie online TelefonSeelsorge https://www.telefonseelsorge.de/ Junge Menschen unter 25 finden Unterstützung per Mail bei [U25] unter https://www.u25-deutschland.de/ Jugendliche und junge Erwachsene bis 27 Jahren sowie ihre Bezugspersonen finden Hilfe bei Lebenslicht, der psychologischen Beratung der Caritas Gelsenkirchen https://www.caritas-gelsenkirchen.de/wir-helfen/kinderjugendundfamilie/beratungkinderjugendundfamilie/lebenslicht-suizidpraevention/lebenslicht-suizidpraevention

In this podcast my guests Sherry Jackson Thompson, Director; Wylie Caudill, Steve; and Kyle Wade, numerous roles - all female - discuss the upcoming production of Jeffrey by Act Out Theatre, exploring its themes of love, humor, and the impact of the AIDS crisis. They share insights into the mission of Act Out Theatre, the character dynamics within the play, and the challenges of rehearsing without a dedicated space. The discussion highlights the relevance of the play in today's context, emphasizing the importance of community and inclusivity in theatre.Jeffrey was written in the shadow of a profound public health and social crisis. Opening off-Broadway to much success in 1992, the play emerged during the AIDS epidemic, when fear, stigma, misinformation, and political inaction shaped the lives of countless Americans. Although the circumstances are different, the parallels between then and now are disturbingly similar.The early 1990s in America were marked by deep social and political divisions. Many people living with HIV and AIDS faced discrimination, isolation, and the loss of friends and loved ones while public institutions struggled to respond with the urgency the crisis demanded. The Reagan administration had been widely criticized for its delayed and inadequate public response during the early years of the epidemic, a failure that intensified the pain experienced by affected communities. These circumstances helped fuel activism and demanded that the public confront the human cost of silence.Today, as we recognize disturbing parallels between now and then – we honor humor and heart as a means to a kinder day. Sadly, communities still confront social injustice, political polarization, and marginalization today. For more and to connect with us, visit https://www.artsconnectlex.org/art-throb-podcast.html

On October 2, 1985, Rock Hudson — the dashing, legendary Hollywood icon whose magnetic screen presence, classic good looks, and effortless charm made him one of the defining leading men of Golden Age cinema — died of AIDS-related complications in his Beverly Hills home at the age of 59. Hudson had spent the better part of three decades commanding the silver screen, first through sweeping romantic dramas like Written on the Wind and Giant—the latter earning him an Academy Award nomination—and later through a celebrated run of slick, witty romantic comedies alongside Doris Day, including Pillow Talk. Hudson's death marked a watershed cultural moment, forcing the public and the media to confront the AIDS epidemic on a global scale and turning his personal tragedy into a pivotal catalyst for public awareness, research funding, and activism. Hosts: Jason Beckerman, Derek Kaufman Learn more about your ad choices. Visit podcastchoices.com/adchoices

What if some of the most painful parts of your story became the very places God used to shape the way you lead? Zahara McCoy was born in Uganda and lost her mother during the AIDS epidemic when she was just ten years old. Without a parent to advocate for her, her future became incredibly uncertain. But through sponsorship, Zahara was connected with Marianne McCoy in California, a relationship that eventually led to adoption, education and an entirely different future. Years later, Zahara returned to Uganda and encountered children facing circumstances painfully similar to those she had once experienced herself. It became a pivotal moment in her story: she was no longer the child needing someone to step in for her; God was now giving her the opportunity to step in for someone else. Today, Zahara leads Children of Grace, the organisation her adoptive mother began, supporting vulnerable children in Uganda through education, mentorship and holistic care. In this conversation, we talk about Zahara's journey from Uganda to America, faith, identity, advocacy and how our lived experiences can profoundly shape the leaders we become.   A Leadership Truth to Take Into Your Week One of the things that stayed with me after this conversation was Zahara's statement: “Identity precedes performance.” Leadership isn't only shaped in boardrooms, qualifications or positions of authority. Sometimes God uses the very experiences we would never have chosen to develop our compassion, perspective, courage and ability to advocate for others. So perhaps the question to take into this week is: What has God allowed me to walk through that could now help me lead and serve someone else well?   Connect with Zahara You can connect with Zahara and follow her work on social media: Instagram: @zaharamccoy X: @zahara_mccoy Children of Grace https://www.childrenofgrace.com/ Sponsor a child https://childrenofgrace.donorshops.com/sponsorship

A stark advert picturing a gravestone chiselled with ‘AIDS: DON'T DIE OF IGNORANCE' captured the horror of this disease in the 1980s. Now, for HIV-infected people able to access anti-retroviral therapies, life expectancy is normal.How were these amazing medicines developed and how have they transformed lives? Why is it so difficult to eradicate HIV or to develop a vaccine to prevent infection? What does the future hold in the quest to stop the global scourge of AIDS?This lecture was recorded by Matt Higgins  on the 16th of September 2026Matt studied natural sciences at Christ's College in the University of Cambridge and a Ph.D. in structural biology at the Laboratory of Molecular Biology. He started his research group with a Royal Society University Research Fellowship in 2005 and moved to the University of Oxford in 2010. He is currently the E. P. Abraham Professor of Structural Biology and a Professorial Fellow at Merton College, Oxford. He is a Fellow of the Academy of Medical Sciences and a member of the European Molecular Biology Organisation.The transcript of the lecture is available from the Gresham College website: https://www.gresham.ac.uk/watch-now/hiv-pandemicGresham College has offered free public lectures for over 400 years, thanks to the generosity of our supporters. There are currently over 2,500 lectures free to access. We believe that everyone should have the opportunity to learn from some of the greatest minds. To support Gresham College's mission, please consider making a donation: https://www.gresham.ac.uk/get-involved/support-us/make-donation/donate-today Website:  https://gresham.ac.ukX: https://x.com/GreshamCollegeFacebook: https://facebook.com/greshamcollegeInstagram: https://instagram.com/greshamcollegeBluesky: https://bsky.app/profile/greshamcollege.bsky.social TikTok: https://www.tiktok.com/@greshamcollegeSupport Us: https://www.gresham.ac.uk/get-involved/support-us/make-donation/donate-todaySupport the show

Better squeal for me you little piggies,  because David Lauterstein, the co-founder and CEO of Nasty Pig, joins Mike and Kyle to talk about the origin story of Nasty Pig, starting a business with his husband, Pride in the time of AIDS, sex positivity, Fire Island vs. P-Town, Honey Davenport, fetish gear, advocacy during mpox, his book “Sodomy Gods” (https://store.nastypig.com/products/sodomy-gods-book), now available on audio book, and embracing the sluttiness. In this episode: News- 1:28 || Main Topic (Nasty Pig)- 10:52 || Guest (David Lauterstein)- 13:17 || Gayest & Straightest- 50:37 Follow @david_lauterstein and @nastypig on Instagram, and learn more about Nasty Pig or shop their latest collection at nastypig.com. If you want to watch a video version of the podcast, you can find it on Spotify or on YouTube. We'll also be posting clips to our brand new TikTok. Plus, get access to tons of bonus video content and a weekly livestream of our full recording session if you're a $10+/mo member on Patreon. If you want to join Mike and Kyle on their 2027 Mexican Riviera cruise, visit gayishpodcast.com/cruise to sign up. Make sure to check Gayish as the podcast you're attending for. On the Patreon bonus segment, Kyle shares with Mike recent blog posts from the Nasty Pig website in what becomes quite the controversial segment. If you want to support our show while getting ad-free episodes a day early, go to www.patreon.com/gayishpodcast. Get the full scoop on all the exciting additions we've recently made to Patreon: https://www.patreon.com/gayishpodcast/posts/exciting-news-163749474.

Dr. Justin Abbatemarco talks with Dr. Irene Cortese about recent advances in the treatment of progressive multifocal leukoencephalopathy (PML), focusing on immune-based therapies like virus-specific T cells and immune checkpoint inhibitors.  Read the related article in The New England Journal of Medicine.  Disclosures can be found at Neurology.org.  Show transcript:  Dr. José Merino: This is José Merino, editor-in-chief of the Neurology Family of Journals. The Neurology Podcast provides practical information to neurologists and other clinicians to help them provide better care for their patients. Thanks for listening, and have a great week. Dr. Justin Abbatemarco: Hello and welcome. This is Justin Abbatemarco with the Cleveland Clinic here with Irene Cortese to discuss an update on progressive multifocal leukoencephalopathy treatment in light of a New England Journal of Medicine correspondence, Resolution of PML After Treatment with Virus-Specific T Cells and HCT. Irene directs the Experimental Immunotherapeutics Unit at NINDS. Hello and welcome. Dr. Irene Cortese: Hi, thank you for the invitation to join you today. Dr. Justin Abbatemarco: It's a pleasure to have you on and to talk about this expanding space in rare disease. And maybe if we could start off, can we just take an overview on how PML usually presents and why does it remain so difficult to treat? Dr. Irene Cortese: PML, or progressive multifocal leukoencephalopathy, is an opportunistic infection of the brain that is caused by the JC virus. And most of us carry this virus lifelong and without any symptoms, and it really only causes disease when the immune system is significantly compromised and loses the ability to keep it in check. And so when that happens, the virus can gain the ability to infect oligodendrocytes, and this can lead to the rapidly progressive demyelinating infection called PML. These lesions that develop in PML are typically located in the white matter, and they are most often multifocal. And this leads to the clinical manifestation of a combination of cortical and subcortical symptoms that evolve over weeks to months. And, unfortunately, if immune competence can't be restored quickly, then the disease is fatal within just a few months. And so that's really the core of the problem here, is that there is no effective direct antiviral treatment. And the only thing that works is restoring the immune system ability to control it, but that's often very difficult to do. When it's even possible, it's frequently just not even fast enough. And so you can see this even in situations where you'd think that we'd have an advantage, for example, in HIV-associated PML, where we do have effective antiretroviral therapy. Even there, restoring immune competence can sometimes just take too long relative to how quickly PML progresses. And so on top of all that, PML is really quite rare and is also remarkably heterogeneous because it can occur in very different patient populations from HIV to hematological malignancy to genetic immune deficiencies. And this rarity and heterogeneity really make both the diagnosis difficult and also treatment development quite difficult. Dr. Justin Abbatemarco: It's such a interesting story, and these different backgrounds really present different challenges. But at these last few years, this has been a success story in some way because we've seen so much effort and research into this rare disease space, which is encouraging. We mentioned this at the top, but there are immune checkpoint inhibitors that have at least been trialed for this T cell exhaustion to see if we can boost the immune system, and then more recently with your work around allogeneic-specific T cells to help clear the infection. What have you taken away from those updates? Dr. Irene Cortese: The biggest takeaway is that these two approaches, checkpoint inhibitors and Virus-Specific T Cells, have really transformed the way that we think about PML. So for decades, our only option was really to try to reverse the underlying immune suppressive condition and just hope that the immune system caught up in time. And now we have these two active strategies to try to speed this process up. Importantly, both these strategies have validated the same core hypothesis that even without a direct antiviral agent, we can improve PML outcomes by restoring effective antiviral immunity. And that said, each of these approaches has real limitations. So first of all, they don't work in all patients. And we have best estimates of success rates somewhere in the 50 to 60% range overall. With checkpoint inhibitors, the fundamental issue is that you're trying to unleash an immune response that has to already be there in some latent or exhausted form. For example, in patients with very advanced immune compromise where the T-cell compartment is essentially absent, there's just nothing left to invigorate, and so checkpoint blockade is really unlikely to help. And even when they do work, there is a real risk of exacerbating underlying autoimmune disease as well as the risk of leading to immune reconstitution inflammatory syndrome, or IRIS, where inflammation in the central nervous system of this immune system waking up and attacking the infection can actually lead to severe morbidity and even death in some patients. Virus-Specific T Cells have a whole different set of limitations. These are mostly practical and logistical at this point. Access is really the big one because there are only a handful of centers worldwide that can manufacture Virus-Specific T Cells. And so this just isn't something you can easily do everywhere or quickly. And also, biologically, every virus-specific T-cell product which is made from a different donor is essentially a different drug. And so it's really hard to predict how any given cell product will actually behave in a given patient. I should also mention that for both these approaches, they truly are still experimental. We don't have any controlled studies, and so most of what we're working from is really retrospective series and case reports. And we definitely have no head-to-head data. And so while we apply general principles estimating residual immune capacity or weighing the risk of exacerbating immune-mediated adverse events, we're really making individualized judgment calls rather than following an evidence-based algorithm. Dr. Justin Abbatemarco: And could you talk about those Virus-Specific T Cells? It's not something we use commonly in neurology. How do those work? And have they been used in other spaces successfully that we've been able to maybe apply some of those principles here? Dr. Irene Cortese: Yeah. So Virus-Specific T Cells were really first developed in the transplant setting, and they were essentially a way to bridge patients immediately following myeloablation. And in the period of time it took them to fully immune reconstitute a brand new immune system, it was a way to protect them from the common viral infections mostly that can develop in this time period and that led to such high morbidity and even mortality. And so the way this is done is that you basically take healthy lymphocytes from a healthy donor, and you can train them in vitro by ex vivo expansion and stimulation to basically become professional killers of the particular virus of interest so that, at the end of this expansion period, you basically have a enriched antiviral product that can be adoptively transferred to the patient recipient. And they may not last for a very long time, however, they can, especially with repeated infusions, provide the necessary immunity to bridge until definitive immune reconstitution is achieved. And so the initial experience with Virus-Specific T Cells was really against the various viruses that are so common in the post-transplant setting, like CMV, EBV, adenovirus, and also BK virus, which is a cousin, let's say, of the JC virus. And over time, the process for manufacturing Virus-Specific T Cells has become more and more streamlined. And so back as in 2015, 2017, we started to realize that perhaps these types of cell products might even be used to treat an acute infection and not just to administer in the setting of a planned transplant. And so essentially we've done exactly this, basically copied these manufacturing methods from the transplant world to make Virus-Specific T Cells against the JC virus and can then use them to treat PML. I should mention that BK virus is very similar in structure to the JC virus. And for that reason, what we learned early on when we started to apply Virus-Specific T Cells to the treatment of PML was that we could actually use Virus-Specific T Cells that were made against BK virus and successfully treat PML. More recent years, groups have been manufacturing JC virus-specific BST, but those BK Virus-Specific T Cells can still be used to treat PML. Dr. Justin Abbatemarco: That's really incredible. And it's so cool when we borrow things from these other fields to help inform rare diseases within neurology space. Maybe it's a perfect segue into the cases report in New England Journal of Medicine where you had two cases with inborn errors of immunity. You've utilized the strategy and then stem cell transplant. Walk us through those cases. What did you see? What did we learn from these that we can apply more broadly? Dr. Irene Cortese: Our paper really told the story of our experience of treating these two young men. Both of them had developed PML in the setting of an inborn error of immunity. One of them had DOCK8 deficiency, and he also had Sézary syndrome as a comorbid condition. And the second patient had a CD40 ligand deficiency. And for both these patients, we basically adopted the same strategy, which was to first try to gain control of the JC viral infection. And once that infection was actually under control, then we went ahead and proceeded to definitive treatment of their underlying genetic immune deficiency, which was transplant in their setting to correct the real root problem that they had. And what I think was perhaps most instructive in this experience is what happened after transplant in both cases. So transplant obviously involves a period of renewed immune vulnerability, and that's exactly when we feared that the PML might come back, even though we had been able to gain control, at least temporarily, using this adoptive transfer Virus-Specific T Cells. Fortunately, in these two cases, that didn't happen. And in fact, patient one actually developed IRIS shortly after engrafting with worsening neurological symptoms and also imaging that showed active inflammation, which responded well to steroids. And he's now years out with no evidence of PML or his prior malignancy, which was also treated by the transplant. The second patient's course was complicated by cryptogenic organizing pneumonia, or COP, which can happen in the post-transplant setting, and did require steroids. And this did cause a transient uptick in the JC viral copy number in the spinal fluid, but this resolved once the steroids were tapered. And this patient also is now several years out with only mild residual neurological deficits. So it's important that for both these patients, the transplant donors, in addition to undergoing collection for the transplant itself, they also underwent a collection to make extra rescue Virus-Specific T-Cell products that we had on hand just in case the PML relapsed post-transplant, which of course was not, in the end, needed. And so basically, the overall strategy for both these patients was sequential and deliberate. First to establish virus-specific immune control, and only then proceeding to the definitive but higher risk step of transplant with the safety net available in case virus reactivated during that post-transplant period. Dr. Justin Abbatemarco: The complexity of these cases, though, and the successful outcome is just incredible. And again, we don't always treat these level of patients, but most neurologists will see PML during their career. How do you think this helps inform this broader field of PML treatment in your mind? Dr. Irene Cortese: For me, these two cases really crystallized the idea of immune facilitation as a bridge rather than as a standalone endpoint. For example, in these two patients, Virus-Specific T Cells could not have led to a definitive cure because the underlying immune defect was still there, but they could buy time and control the virus long enough to get to something that could actually fix the underlying problem, which in this case was the transplant. And I'll be honest, proceeding to transplant in a patient with active or recent PML was really frightening. And clearly that is not an option or appropriate at all for the majority of patients with PML. So I guess that the broader lesson here is that Virus-Specific T Cells or potentially other immune-facilitating strategies might serve as a bridge to get us to the point where we either have a way to address that root cause of immune suppression or just buy us the time needed to recover from immune suppressive exposures and perhaps opens up the question of how we might use sequential strategies and combinations of strategies to optimize the care of these patients. Dr. Justin Abbatemarco: Really appreciate your paradigm of how you think about these cases in treatment, and yet you can have these short-term strategies to bridge patients to have an improved immune response to get this under control. Could we talk about other common examples? So we have natalizumab-induced PML cases, HIV-associated PML cases. How would you think about managing those, so outside of these inborn errors of immunity? Dr. Irene Cortese: Each PML patient is somewhat unique, and definitely the underlying condition that is driving the immune suppressed state is really critical in mapping out what we need to do. I think of HIV-associated PML or even natalizumab-related PML as being somewhat unique. Because unlike most other causes of PML, we actually do have clear and reliable ways to restore immune competence, so basically antiretroviral therapy in HIV infection or simply discontinuing the non-immune-depleting drug natalizumab in the case of natalizumab-related PML. And so this is obviously a real advantage compared to many of the other underlying conditions where there really is no good way to reverse that immune suppression at all. That said, in some patients, for example, with advanced AIDS and very low CD4 counts, immune reconstitution can still be very slow even when the HIV replication itself is well controlled. And so in a subset of patients, the PML can still really pace the recovery. And so we do sometimes need strategies to bridge that gap. And basically. we would consider the same immune restoration approaches that we've been talking about right now. There is an added layer of complexity here that's a bit more, let's say, unique to HIV-related PML or to the setting of natalizumab-related PML, which is that in both these cases, immune reconstitution is going to happen eventually. And when it does, then many of those patients do experience PML IRIS where the constituting immune response paradoxically worsens the neurological injury by attacking the infected tissue. And so this really needs to be watched for and managed typically with steroids. And certainly this risk of developing PML IRIS needs to be really considered if we are going to use strategies to boost or facilitate immune reconstitution in the setting of HIV infection or natalizumab-related PML. And we just have to be particularly mindful because there's already a very high likelihood of developing PML IRIS independently of getting that extra boost. Comparatively, in the setting of non-HIV-related PML or not in the setting of natilizumab treatment, I think that strategies like checkpoint inhibition and Virus-Specific T Cells have really been game-changing because, historically, these patients had no equivalent to antiretroviral therapy with no reliable path to reconstituting immunity. And we're really hoping that these approaches will start to bring the outcomes that we've seen, for example, among HIV-related PML and in the setting of natalizumab and PML to these other underlying conditions and achieve the same immune control and survival rates that are achieved in at least a substantial portion of these patients. Dr. Justin Abbatemarco: It's been so exciting. Again, the updates in this field when we really did... We had nothing to offer patients for so long and now to have conversations that are a little bit different. Can I ask you to peer around the corner? What does the future look like in your mind? Do you see other therapies that are potentially at play and maybe right now are there clinical trials that we could enroll patients so that we can help inform the field more broadly? Dr. Irene Cortese: Yeah. So I think that ways to facilitate and accelerate immune reconstitution have clearly been shown to be a valid strategy. And so what I expect and hope is that in the years to come, we'll learn to harness that better and learn to identify which patients are most likely to respond to particular types of strategies to facilitate immune reconstitution. It's really important, I would say, that patients participate in trials because the field really does lack controlled data and it lacks head-to-head comparisons. And so every patient enrolled in a trial or a well-structured registry is really contributing to how the next patient gets treated. And given just how rare and heterogeneous PML is, we're just not going to advance this field through isolated case reports alone. And so we really do need patients and their physicians to be willing to participate in structured and collaborative research. The Holy Grail is, of course, a direct antiviral agent that would really broaden our ability to treat patients and potentially also continue to treat whatever that underlying condition was that led them to the risk of PML in the first place, so, for example, patients receiving treatment for cancer or patients having an autoimmune disease that requires immune suppression. And so I am hopeful that eventually the direct antiviral will be identified. And along that line, what I can mention is there are certainly clinical trials that are ongoing. At NIH, we have an active natural history study from where we can funnel patients into various experimental treatment strategies, including Virus-Specific T Cells or checkpoint inhibitors. Or right now, we actually do have an ongoing trial of intravenous brincidofovir as a possible direct antiviral strategy. What I hope for the future is that we will find ways to really collaborate and to form national as well as international consortia so that we can accelerate the development of these treatments. Dr. Justin Abbatemarco: We have things we can do now, and then we can help inform care for our future patients as well. So these are great messages, and I can't thank you enough for coming on. Again, most of these developments have been under your guidance, and we appreciate your leadership in this space and helping to give us this insight into this really rare disease. For folks, they can check out the article. It's in the New England Journal of Medicine, Resolution of TML After Treatment with Virus-Specific T Cells and HCT. Irene, thank you for coming on. Dr. Irene Cortese: Thank you so much. Dr. Stacey Clardy: This is Stacey Clardy, your podcast editor. If you've enjoyed the podcast, please take a few moments to subscribe, rate, and review the Neurology Podcast through Apple Podcasts, Google Podcasts, Spotify, or wherever you listen. And remember, you can always head to neurology.orgpodcast for our full list of past episodes, or you can also search by keyword on your podcast app for any neurology-specific topics.

China aids Cuba as U.S. hostility backfires. MTG turns the socialism attack on Republicans. Sully Dawg challenges GOP jobs and debt claims. Rubia Garcia brings working-class voices to Louisiana LA-6.Subscribe to our Newsletter:https://politicsdoneright.com/newsletterPurchase our Books: As I See It: https://amzn.to/3XpvW5o How To Make AmericaUtopia: https://amzn.to/3VKVFnG It's Worth It: https://amzn.to/3VFByXP Lose Weight And BeFit Now: https://amzn.to/3xiQK3K Tribulations of anAfro-Latino Caribbean man: https://amzn.to/4c09rbE

"This Gay Week: Progress and Panic, All in 7 Days" It's This Gay Week on The Karel Cast — and this week proves LGBTQ rights are moving in every direction at once, sometimes in the same breath. Turkey just arrested 241 people in an anti-trans sweep so severe that human rights groups are now demanding the EU freeze its accession bid entirely. Indonesia has officially classified "LGBTQ culture" as a national security threat, grouped alongside terrorism. Colombia just quit the world's largest LGBTQ rights coalition mid-term. And in the Netherlands — long seen as Europe's most tolerant nation — acceptance among teenage boys has nearly been cut in half in just four years, a number even the country's own gay Prime Minister calls "shocking." Closer to home, Southlake, Texas quietly killed a Pride festival's permit with zero explanation, one year after approving the same event. And outside a Liverpool LGBT bar, a stabbing has three men hospitalized — police haven't confirmed a motive, but Karel asks the question anyway. But it's not all bad news: Hungary, freed from 16 years of Viktor Orbán, is actively repealing his anti-LGBTQ "promotion" laws — proof governments can turn around faster than people expect. And Anthony Fauci is being honored for a legacy that started in the trenches of the AIDS crisis, alongside Pennsylvania's first openly transgender mayor. Karel connects the dots on what's really a week-long lesson: legal progress, social acceptance, and institutional protection don't move together — and sometimes they move in opposite directions in the same seven days. Join the conversation in the comments: What is the single biggest thing you do for your health every day? LIKE this video, SUBSCRIBE to The Karel Cast, and SHARE it with someone who needs to hear this conversation. Support independent media at Patreon: patreon.com/reallykarel Watch and subscribe: youtube.com/reallykarel The Karel Cast is available on Apple Podcasts, Spotify, iHeartRadio, Spreaker and other major podcast platforms, plus TikTok and Instagram. LIVE Monday–Thursday at 10:00 a.m. Pacific. Karel is a history-making broadcaster, entertainer and commentator based in Las Vegas, joined by his little service dog, Ember. #LGBTQ, #KarelShow, #LasVegas, #ThisGayWeek, #Turkey, #Hungary, #PrideMonth, #HumanRights, #LGBTQNews, #Colombia, #Netherlands, #Uganda, #AnthonyFauci, #NewsCommentary, #IndependentMedia https://www.youtube.com/watch?v=s2kvxKFJRIs

Thank you Farmers AGAINST trump., RLM, Cheryl

Cal dives into the intersection of kink, fetish, and health promotion within Melbourne’s queer community through The Laird Hotel’s long-standing Northside Bizarre event. Laird Hotel owner Brett and community legend Tex discuss the evolution of safe sex messaging from early AIDS council campaigns to modern peer-based outreach methods. We also get into the nitty gritty about how venues like pubs and clubs have historically functioned as informal health education spaces beyond traditional medical settings. This year’s Northside Bizarre is set to be bigger and better than ever. Learn more and get involved here: https://www.thorneharbour.org/get-involved/events/northside-bizarre-oct-2026 Chapters 00:00 – Introduction to Northside Bizarre returning after six year hiatus 02:30 – Early HIV prevention posters in queer venues and saunas 05:30 – The Protection campaign using porn industry images for education 10:00 – Taking over The Laird Hotel 15:00 – Peer outreach volunteers distributing safe sex packs at venues 19:00 – Kink and fetish scene health education and venue partnerships 23:30 – Northside Bizarre auction house and memorable moments 28:00 – Leather and Treasure – second hand gear sale origin story 35:30 – Initiative celebrating female bartenders at The Laird 40:30 – Final year auctioneer announcement All chapter timecodes are approximate. Want more Well Well Well? Check out our other JOY Podcasts for more on LGBTIQ+ health and wellbeing at joy.org.au/wellwellwell. If there's something you'd like us to explore on the show, send through ideas or questions at wellwellwell@joy.org.au Find out more about LGBTIQ+ services and events in Victoria and South Australia at thorneharbour.org. Produced by: Caleb Hawk, Jack Crnjanin

One of our most-requested episodes is back. Itamar Marcus, founder of Palestinian Media Watch, sits down with Laurie Cardoza-Moore to reveal what Palestinian television, textbooks, and summer camps actually teach children — in their own words, not the version prepared for Western audiences.The claims go further than politics. Marcus documents Palestinian state television glorifying the murder of Jewish children as heroism, and Hamas — a branch of the Muslim Brotherhood — calling for a global war that ends with the world under Islam. He also traces how American tax dollars help fund the incitement.For over a decade, Palestinian Media Watch has kept this record in the Palestinians' own words — learn more at palwatch.org. Follow, share, and support PJTN's work defending truth and Israel at pjtn.org.00:00 Cold Open: The Fogel Family Murders & Hamas's Message01:02 Meet Itamar Marcus & Palestinian Media Watch02:32 Naming Terrorists as Heroes: Soccer Tournaments & Summer Camps03:47 The Libels: Blaming Israel for AIDS, Mosque Destruction, and More04:59 A Child on TV: "I Think the Jews Poisoned Him"05:58 UNRWA: Perpetuating the Refugee Crisis09:03 Western Funding for "Pay-for-Slay" Salaries09:59 Inside the Summer Camps: Teaching Children to Kill11:49 Palestinian Textbooks: Denying Israel's Right to Exist13:33 Glorifying Terrorists as "Heroic Fighters"14:39 The Vanishing Christians of Bethlehem17:23 Hamas Targets Christians Too18:26 Gaza: What "Land for Peace" Actually Bought19:47 Why Peace Requires Education First21:08 The Truth About the 1967 Borders22:35 How Israel Developed Judea and Samaria23:52 The Fogel Family: A Massacre Revisited24:37 Glorified on TV: The Killer's Mother Speaks25:32 The Playbook: Reward Before, Glorify After26:54 Iran's Nuclear Threat Isn't Just Israel's Problem29:11 Closing & How to Support PJTNDon't forget to subscribe, rate, and share to help us equip more Christians to stand with Israel and fight antisemitism.✨ Stay connected with PJTN! ✨

It was once a diagnosis widely believed to be an absolute death sentence, but much has changed since the earliest years of the AIDS epidemic. There have been tremendous advances in detection and treatment which have dramatically improved health outcomes for millions. Still, an estimated 1.2 million people in the U.S. are living with HIV, and 13% of them don’t know it. That gap is tied to barriers in access to testing, treatment, and ongoing care, and it continues to contribute to increases in new diagnoses. On today’s special edition of Closer Look with Rose Scott, we look beyond the disease itself to examine how stigma is also a factor. Our panel discusses efforts to confront and reduce stigma surrounding HIV/AIDS. If you or someone you know is in need of testing for HIV/AIDS, you can access these resources: AID Atlanta, Grady Healthcare, Cobb & Douglas Public Health, CVS Minute Clinic, AvitaCare Atlanta. Guests: Jerrell Hardnett, associate director of education & advocacy at GLAAD, and the author of GLAAD's sixth annual State of HIV Stigma Report Tim'm West, executive director of Rustin Institute Nicole Roebuck, Executive Director of AID Atlanta Pastor Eric Thomas, Saint Peter Missionary Baptist Church and a founder & President of Metro Atlanta Ministerial AllianceSee omnystudio.com/listener for privacy information.

Friends are for making hit charity singles to raise money for AIDS research apparently. Coverrs by: Dionne Warwick with Elton John, Stevie Wonder and Gladys Knight; Perry Como; Mercury4; Maiya Sykes & Hugh Sheridan Tidal playlist HERE

The rise, fall and rise of the most nonsensical conspiracy theory we've ever heard.Thanks to Gregg Gonsalves for helping us fact-check this episode! Support us:Hear bonus episodes on PatreonWatch Aubrey's documentaryBuy Aubrey's bookListen to Mike's other podcastGet Maintenance Phase T-shirts, stickers and moreLinks!Denying AIDS: Conspiracy Theories and Pseudoscience in a Post-COVID WorldImpure Science: AIDS, Activism, and the Politics of KnowledgeThe Duesberg PhenomenonAIDS Denialism Beliefs among People Living with HIV/AIDSHIV Denial in the Internet EraHIV Denial in the COVID EraHow COVID conspiracy theories led to an alarming resurgence in AIDS denialismThe Man Who Thought AIDS Was All In The MindAIDS "Dissident" Seeks RedemptionTruth and Heresy About AIDSDefending the boundaries of scienceJustice After AIDS DenialismAIDS Denialism vs. ScienceThe UnbelieverEstimating the lost benefits of ARV use in South AfricaConspiracy beliefs about HIV/AIDSAre HIV/AIDS Conspiracy Beliefs a Barrier to HIV Prevention Among African Americans?HIV causes AIDS: Koch's postulates fulfilledAIDS And The Scientific Governance Of Medicine In Post-Apartheid South AfricaThe DenialistsHas Duesberg a right of reply?Thanks to Doctor Dreamchip for our lovely theme song!Support the show

EA773 - Leather Contests, Columbus Kink Community & 2027 Events This week on the Erotic Awakening Podcast, episode 773, Dawn shares her experience and some history on Leather Title contests…. …plus, she reflects on her home community, Columbus OH….and a bit about the events she'll be presenting at next year with a little bit of a soap box moment on events that don't value quality presenters.    LINKS MENTIONED:   Scissortail https://fetlife.com/events/2026/09/25/scissortail-leather-conference-midwest-power-exchange-contest-sjvqwm Kinky Holiday Bazaar https://fetlife.com/events/2026/11/21/kinky-holiday-bazaar-ogivu7 SEEK submissive retreat https://fetlife.com/events/2026/10/08/submissive-seek-retreat-2026-zdjhi5 TRANSCRIPT 1:13 Leather Contests 5:58 What is a Leather Contest 7:27 Leather Contest in the 80's/AIDS 9:53 Later years, focus shifts again 15:01 Instant Expert Syndrome 17:38 Growth and Inner Reflection 18:06 Judging 22:06 What does a contest look like 28:20 Where I'll be 29:51 Columbus Community 32:18 2027 - Where I will and won't be and why (yes, I got on a soapbox again)   Enjoy!!! Dawn ************************************************************ Enjoy the podcast and the education Dawn shares? Join the PATRONs who help make it possible, for as little as $2/month. Discounted/Free books, kink starter cards, online classes; early access to the show, and more!    https://www.patreon.com/eroticawakening   Or  Donate at KOFI https://ko-fi.com/dawn_awakening ***************************************** Fetlife - @Erotic_Awakening   Fetlife - @Dawn_Awakening Instagram - @eroticawakening Youtube - @eroticawakeningpodcast TikTok - @eapodcastdawn Newsletter - www.eroticawakening.com Discord - https://discord.gg/WQtSM56V39   ******************************************** 773 - #leathercontest #kic #leather #powerexchange #livingms #kinkeducation #onlinekinkeducation #eroticawakeningpodcast #podcast #bdsm #domsub #submission #heartsandcollars  

With his fantastic debut graphic novel, THE NIGHTINGALES (Avid Reader Press), Emil Wilson tells a heartbreaking and beautiful coming-of-age story of the AIDS era. We talk about his father's decision in 1985 to bring a work-friend with AIDS into their home (in a small town in Oregon), how he fictionalized his family and the story well enough to make the fiction true, how he figured out the amazing sketchbook style of the book, and how he only came to comics in his 50s, following a 25-year career as an at director an ad agency. We get into his experiences at The Center for Cartoon Studies, where he was older than most every other student, the Nora Krug book that was his gateway drug into comics, my advice when he began this project, his work as an AIDS buddy for Gay Men's Health Crisis in the '80s and how younger people he meets have no knowledge of the AIDS era, how making The Nightingales changed his understanding of his family, and how it felt to make a "user's manual" for his father. We also get into the contrast between advertising and comics, how making comics can feel a bit like making films or videos, how the language to describe comics may need to evolve just as the language for gay life had to, why this book isn't a memoir but is full of faces, how kindness can be complicated, and more. Follow Emil on Instagram, and Bluesky • More info at our site • Support The Virtual Memories Show via Stripe, Patreon, or Paypal, and subscribe to our e-newsletter

Ngày 19 tháng 9 ghi dấu những bước ngoặt quan trọng của nhân loại. Từ cuộc chiến làm thay đổi vận mệnh châu Âu, đến quyền bầu cử của phụ nữ, từ những bí mật khảo cổ hàng nghìn năm tuổi cho tới cuộc chiến chống virust HIV gây bệnh AIDS.

My guest today is Tania de Jong, co-founder of Mind Medicine Australia. Tania and her husband, Peter, helped lead the push that, in 2023, made Australia the first country in the world to allow MDMA and psilocybin to be prescribed for psychiatric conditions. I wanted to understand how the hell they helped make that happen and what the rest of the world can learn from it.This episode is brought to you by:ProLon science-backed Fasting Mimicking Diet that helps activate cellular renewal through fasting, while still eating nourishing meals: https://prolonlife.com/TimMomentous high-quality creatine for cognitive and muscular support: https://LiveMomentous.com/TimAG1 all-in-one nutritional supplement: DrinkAG1.com/TimTimestamps[00:00:00] Intro from Tim.[00:02:46] The article that changed Tania's life.[00:04:39] A first psychedelic experience—and the year it took to integrate it.[00:10:17] Rick Doblin's encouragement and the birth of Mind Medicine Australia.[00:13:15] Turning regulatory rejection into a stronger application.[00:20:48] Building a grassroots movement and training clinicians.[00:23:23] Cold emails, scientific allies, and singing your way into the room.[00:31:11] A week with Ram Dass: silence, singing, and an extraordinary LSD story.[00:37:54] Bringing David Nutt—and a family's devastating story—to the regulators.[00:42:42] Dancing in the kitchen: Australia's rescheduling breakthrough.[00:43:40] From changing the rules to treating patients.[00:48:18] Why Tim thinks MDMA is still underestimated.[00:50:23] Integration beyond the session: therapy, nutrition, and exercise.[00:52:29] Scaling access and collecting real-world evidence.[00:58:13] Getting insurers, government agencies, and philanthropists on board.[01:01:39] Syrian rue, psilocybin, and learning to let go of control.[01:10:01] Dosing, expectations, and the pressure to take more.[01:12:02] The promise of group therapy and shared integration.[01:14:22] Hiring mistakes, personal attacks, and the resilience advocacy requires.[01:23:38] Turning a window of change into lasting habits.[01:25:51] Getting through to regulators and pushing for end-of-life access.[01:28:27] The bureaucratic barriers that remain.[01:31:38] What treatment costs—and why therapist time drives the bill.[01:35:07] Could shorter-acting compounds make treatment more affordable?[01:38:46] Ketamine, kratom, and the limits of “all natural.”[01:43:14] The unexpected payoff from Tim's ketamine experiment.[01:47:46] What might come next for psychedelic access worldwide?[01:49:04] Persistence versus pushiness—and knowing when to try another door.[01:54:22] Supporting patients and training the next wave of clinicians.[01:57:51] “Be curious”: exploring your inner world and walking each other home.[02:01:35] The ripple effects of sharing your curiosity—and simply asking for help.Timeline:February 2, 2015: Michael Pollan publishes “The Trip Treatment” in The New Yorker, which is the article Tania credits with setting her journey in motion.March 21, 2015: Tim releases his James Fadiman interview, “The Psychedelic Explorer's Guide” (#66). Its show notes link to “The Trip Treatment.”January 15, 2016: In 5-Bullet Friday, Tim announces support for Johns Hopkins' psilocybin research and a personal commitment of at least $100,000 toward psychedelic research that year.2016: Tania and Peter travel to the Netherlands for their first guided psilocybin experience. (Source)2017–2019: UCSF conducts the psilocybin-assisted group-therapy study involving long-term AIDS survivors that Tim helped support. (Source)May 6, 2018: Michael Pollan joins Tim for “Exploring the New Science of Psychedelics” (#313), discussing his forthcoming book (How to Change Your Mind).May 15, 2018: Pollan's How to Change Your Mind is published.February 13, 2019: Tania and Peter publicly launch Mind Medicine Australia. (Source)2020–2022: MMA applies to reschedule MDMA and psilocybin, faces rejection, and submits new applications in March 2022. (Source)November 21, 2022: David Nutt presents to Australia's medicines regulator, the TGA, supporting the case for therapeutic access. (Source)February 3, 2023: The TGA announces restricted prescribing access to MDMA for PTSD and psilocybin for treatment-resistant depression, effective July 1, 2023. (Source)January 2024: Patients begin receiving treatment under the new prescribing program. (Source)*For show notes and past guests on The Tim Ferriss Show, please visit tim.blog/podcast.For deals from sponsors of The Tim Ferriss Show, please visit tim.blog/podcast-sponsorsSign up for Tim's email newsletter (5-Bullet Friday) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Discover Tim's books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissYouTube: youtube.com/timferrissFacebook: facebook.com/timferriss LinkedIn: linkedin.com/in/timferrissSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The Speaker: A New Podcast on Nancy Pelosi's Unlikely Path to Power Ahead of Nancy Pelosi's retirement, KQED's Scott Shafer traces her improbable 1987 rise in a new podcast The Speaker: How Nancy Pelosi Changed the Face of Power. The first episode revisits her primary against Democratic Socialist Harry Britt, who had hoped to become San Francisco's first openly gay congressman amid the AIDS crisis — a race Pelosi narrowly won on her way to becoming one of the most powerful women in American politics. Learn more about your ad choices. Visit megaphone.fm/adchoices

Plugged In's Adam Holz offer a preview of many of the movies and shows coming to streaming this fall, a few and swinging back to ones aimed at teen girls that celebrate witchcraft.  How do we navigate this with our kids?  Then along with more thank you's for your support during our Fall Fundraiser, Carmen looks at the rise of HIV on the island of Fiji, as well as the move by the city of Minneapolis to reopen bath houses that were closed back during the AIDS crisis of the 1980's.   The Reconnect with Carmen and all Faith Radio podcasts are made possible by your support. Give now: Click here!  

Michael Brady says he has perfect clients and he means it.Frank sits down with Michael, founder of Generosity Wealth Management, to unpack how his career took a hard turn away from traditional financial planning. Michael shares the story of a longtime client, one of the first AIDS doctors in Boulder, who retired and went on to train doctors in Uganda, a moment that pushed Michael to eventually take two years off with his wife to travel and volunteer before starting his own firm in 2008.Michael shares how upfront he was with prospective clients from day one about exactly what kind of advisor he is, so the people who are not a fit filter themselves out naturally, a dynamic Frank names himself, calling it positive friction. Frank pushes him to explain what having perfect clients actually looks like in practice and Michael walks through how deeply charity is woven into his firm, from inviting clients onto nonprofit boards alongside him to requiring every advisor at Generosity Wealth Management to serve on a board of their own.The conversation covers how this approach builds real trust and referrals, not just goodwill and why Michael believes purpose driven practices attract clients who stay for decades.Questions answered in this episode include:What does it mean for a financial advisor to have perfect clients?How do you build a financial advisory practice around philanthropy?What is positive friction and how does it help attract the right clients?How can financial advisors get their clients involved in charitable boards?Why does Generosity Wealth Management require advisors to serve on a nonprofit board?How do you know if a charity or nonprofit is legitimate before getting involved?What does it look like to build a business centered on purpose instead of just revenue? Chapters:00:00 Introduction: Perfect Clients 01:06 From Financial Planning to Purpose 06:35 Founding Generosity Wealth Management 07:24 What Perfect Clients and Positive Friction Really Mean 12:14 Integrating Charity Into Every Client Relationship 19:28 Turning Clients Into Board Members 29:30 Why Every Advisor at the Firm Must Give Back 37:10 How to Reach Michael Brady Michael Brady, Generosity Wealth Management: https://generositywealth.comResources:- Elite Consulting Partners: https://eliteconsultingpartners.com- Elite Marketing Concepts: https://elitemarketingconcepts.com- Elite Advisor Successions: https://eliteadvisorsuccessions.com- JEDI Database Solutions: https://jedidatabasesolutions.com- Elite Wealth Management Insights Report: https://eliteconsultingpartners.com/insight-report- Listen to more: https://eliteconsultingpartners.com/podcasts/- LinkedIn: https://www.linkedin.com/company/elite-consulting-partners/

Download from https://vovilibrary.net = Vo Vi Library, and repost in podcastPodCast ChannelsVô Vi Podcast - Vấn Đạo Vô Vi Podcast - Băn GiảngVô Vi Podcast - Nhạc Thiền

In this episode, I have the pleasure of speaking with Dr. Neil Nathan about the intersection between brain symptoms and complex illness. Dr. Nathan has practiced medicine for over 50 years. He is one of the leading experts in complex chronic illness and mold toxicity — author of the bestselling Toxic: Heal Your Body from Mold Toxicity, Lyme Disease, Multiple Chemical Sensitivity, and Chronic Environmental Illness and The Sensitive Patient's Healing Guide. I am grateful to call Dr. Nathan a mentor and colleague. His pioneering work has been responsible for my healing from chronic illness, as well as that of many patients I've treated. Together, we co-lead a small peer group (within the larger mentoring group he provides with Marie Matheson, ND), supporting practitioners who treat those with complex chronic illness.In this episode we discuss:03:43 – Dr. Nathan's path to understanding complex illness11:20 – Why complex illness is rising and underrecognized19:30 – Why new medical ideas take decades to reach patients23:15 – Mold, Lyme, and long-COVID: the “big three” root causes25:58 – The limbic-vagal-mast cell “trifecta”30:31 – Are some people born more vulnerable?44:39 – The risk in “just do limbic retraining” advice47:35 - Biochemical contributors49:26 – Structural root: jaw and cervical instability53:58 – Differentiating Between Mold, Lyme & Long-COVID58:49 – A message of hope, and where to learn moreFull Transcript belowYou can find Dr. Nathan's books, consultations and mentoring program through his website at neilnathanmd.com. If you'd like to help get this information out into the world, please consider liking, sharing, or commenting.Until next time,CourtneyCourtney Snyder MDDr. Courtney Snyder MD is a holistic and functional child and adult psychiatrist and host of the Holistic Psychiatry Podcast and can be found at courtneysnydermd.comMedical DisclaimerThis podcast is for educational purposes only and is not intended or implied to be a substitute for professional medical advice, diagnosis, or treatment. Consult your own physician for any medical issues you may be having.Full TranscriptDr. Nathan's Path to Understanding Complex Illness03:43Courtney: I'm so glad we're doing this, and I feel like it's long overdue. As you know, in the mental health space in psychiatry, there's a lot of recognition of a dysregulated nervous system, threat response in the body, but oftentimes that's attributed to external forces or trauma, and not necessarily internal threats that we see, obviously, in complex chronic illness, which we'll be talking about. There's also not the recognition of the relationship between physical symptoms and brain-related symptoms. So I know you're going to help us connect a lot of these dots. As we sort of just lay the groundwork for what complex chronic illness is — when in your path did you start to recognize the distinction, when was the beginning of your work and appreciation of complex health issues?Neil: Okay, there are two answers to that question. First, when I went to medical school, my hope was to become a healer. And I was very disappointed that when I got there, I realized they weren't going to teach me to be a healer. And back then I used to question my professors at medical school — why do you do it this way, and how is that? And I kept feeling in all of our interactions that we were missing something. And my professors would go, “Okay, Mr. Wise Guy, smart guy, what are we missing?” And I'd go, “I don't know, I just know we're missing something.” Later I would come to recognize that we were missing the emotional and spiritual component to whatever was affecting people in their illnesses. And I have language for it now — I didn't then. The person in medical school who influenced me the most was Elisabeth Kübler-Ross, who I view as my main mentor in medical school. She, unlike anyone else, had a one-and-a-half-hour seminar once a week. Back then there weren't video cameras — you were in a small confined room with a two-way mirror, and you're sitting there watching someone do this. And she would simply interview one of her patients. She was a psychiatrist, but she was the only one in medical school who demonstrated how to really listen to people, how to really communicate with them, and not have this standard review of systems — here's my questions, here's your answers, and that's what I do, and this is what I write up. She was really listening. She was trying to really take in, okay, what happened to you, and what's going on with you? So I would want to give her credit as a role model to change how I learn to listen. Okay, that was step one.I'm going to fast forward to the early 1980s. And I am, at that point, the medical director of a regional pain clinic. And we are starting to see a whole bunch of patients who had this complicated process of fatigue, unrefreshed sleep, irritable bowel syndrome, and pain migrating all over their body. And back then we called it fibrositis. Now we call this fibromyalgia. And so whenever medicine encounters a thing that they don't know what they're looking at, it's psychological until proven otherwise. And people would get therapy, and they would take antidepressants and anti-anxiety agents. Didn't help much. And so it became clear to me that we didn't understand what this was at all. It was not psychological. Something was going on in their bodies — now I recognize it as an inflammatory process. Back then there was no concept of that at all. And then, slowly, in the early nineties, we began to find pieces of the puzzle to understand what was triggering fibromyalgia. I was working back then with Jacob Teitelbaum, who did a lot of work with chronic fatigue and fibromyalgia, and we both independently came up with an understanding that a deficiency of magnesium, DHEA, adrenal issues, thyroid issues, sex hormone deficiencies, GI dysbiosis, and food allergy — if we looked at those and treated those, the majority of people with fibromyalgia got cured. It was different for different patients. It was not like there was one thing that caused it. And as time evolved, we began to realize that there was lots of other biochemical imbalances in the body that would contribute to this kind of a process that represented chronic fatigue and fibromyalgia.We discovered that Lyme disease and coinfections was a huge piece of that. And later still we discovered that mold toxicity was a huge piece of that. And so my understanding of the complexity — and it's not really confined to chronic fatigue and fibromyalgia at this point, we're really talking about almost all chronic illness — with a huge psychological component to that. So we've begun to understand this as essentially some version of inflammation. And if we start to really dig into what are the potential causes of that inflammation, we can make a huge impact for them. So this is a multi-year evolving understanding of how a person's genetics, biochemistry, physiology impacts their whole being in every way. And that inflammation extends to the nervous system, contributing greatly, if not causing directly, a large number of what are now called psychiatric diagnoses.Courtney: Right. So even among those patients that you were seeing — you were seeing, I'm assuming, depression, anxiety, brain fog?Neil: Yeah, the vast majority of our patients with mold toxicity have brain fog and anxiety, depression, OCD behaviors, mood swings, depersonalization, derealization. I mean, all of that is super common in our patients.Complex Illness Is Rising — and Underrecognized11:20Courtney: Do you feel like this is more recognized now — or do you feel like the number of people being hit with these complex health issues is increasing — or both?Neil: Both. I would love to say that the medical profession is increasingly recognizing all of this as important, but that recognition is coming very, very slowly. The majority of folks out there, if they were to list the symptoms that they had, their doctors would basically look at them like, “I have no idea what's causing it, so this must be in your head.” And that is the message they're getting from their physicians at this point. So many patients are being gaslighted, so many patients are being told it's in your head. And the repercussions of that are the family is hearing that same message, and the families become less supportive of those people, because they're saying, “This is not real, so why would I support you? This is still in your head, go get your head fixed.” And they're wrong, and it's really a travesty. But so yes, very slowly, this awareness is growing. There are now more medical meetings that I'm aware of where psychiatrists can learn more about this than there were ten, fifteen years ago, for sure. But not enough — it's still not enough.The other part of that is some of the main triggers for this inflammatory process are increasing. So we're seeing more and more mold toxicity, we're seeing more and more Lyme and coinfections, partly because the environment that we are all exposed to has gotten extremely increasingly toxic. So it's now known, for example, that there are 350,000 new chemicals in our environment than existed 70 years ago. The vast majority of those have never been tested for safety in human beings. So human beings have a tremendous amount of chemical exposure that they never had before. Human beings have a tremendous amount of EMF, electromagnetic exposures that they never had before in the history of the human race. So these exposures are cumulative. Our major organs, like our liver and our kidney, that have to deal with toxicity, are overloaded. And so, yes, we are seeing an epidemic of a whole bunch of these conditions. In children, we are aware that autism has skyrocketed — it went from one in several thousand kids to one in thirty kids in many states now have autism. And forgive me, but the pediatric profession is not taking this seriously. It's like, “Yeah, that's sad, it's unfortunate.” It's like — really, you don't want to look at this? This means one in every three kids born are getting autism — does that not concern you? But, forgive me, the medical profession is very slow to embrace new information, and that is really to the detriment.We're seeing an epidemic of Alzheimer's, Parkinson's, ALS, all of which involve neuroinflammation. We've seen already an epidemic of chronic fatigue and fibromyalgia. And all of these things are interrelated, because — yes, I'm supposed to be an expert on mold toxicity, and I probably am — but mold toxicity doesn't exist in a vacuum. You have mold toxicity as one of multiple environmental toxins we're being exposed to. It is simply one of the most common, the easiest one to diagnose, because we have tests for it. We don't have tests for the hundreds of thousands of chemicals out there. We're just beginning to be able to have some tests that will tell us what's in someone's body that might be making them sick.Courtney: Right, right. And I would imagine that this typical medical model of looking for one cause to autism, one cause to dementia — it's a completely different way of thinking. When you get away from that and you look at complexity of the human body, that way of thinking holds back the research, it holds back any progress.Neil: What I think is helpful for people to look at is: we are all uniquely, biochemically, genetically different. And so the same inflammation in one person could trigger cardiovascular disease, and another person could trigger Alzheimer's, and another person could trigger chronic fatigue. So we need to take a step back and go, okay — and this is not a brand new idea. For the last ten years, there are many papers in the medical journals that are saying chronic illness is almost certainly an inflammatory process. Now, it hasn't really integrated into what people are being taught in medical school or in their residency program. But this is not a brand new idea, and there's tons of medical research documenting that.What behooves us as physicians is to look at every human being and go, “Okay, this is your named chronic condition — what are the triggers for you?” We have to kind of be like a medical detective and dig in and go, okay, what's triggering your inflammation, so I can treat the cause — not put a band-aid on it, which is, forgive me, in the psychiatric field, taking antidepressants and benzodiazepines. That's a band-aid. It's a helpful band-aid, it could be a very important band-aid, help someone to function. But you really need to be looking at, okay, I have this great band-aid, but wouldn't it be nice to actually cure this? And I think that would be, for me, to your audience, Courtney, my take-home message — which is always look for the root cause, because it is possible that we will find that root cause, and you won't have whatever name you've been given, depression, anxiety, OCD, for the rest of your earthly life. Maybe.And I've treated thousands of people successfully here. So this is not — I've had one or two successes here — we're talking thousands of people that have responded to this way of practicing medicine, with fabulous results. People who've been literally bedridden, incapacitated by their illness, are now out there working again and being with their family and living full lives. So that's the take-home message.Courtney: Right. Which makes it so satisfying to treat. And I mean, I can speak to that, having experienced it personally. But at the same time, you do get pushback from other areas of medicine that don't give it necessarily credibility, even though people, on the other side, are thriving and healing, and it's really amazing.New Medical Ideas & Research Take Decades to Reach Patients19:30Neil: You know, the history of all science, including medicine, is: new technology, new drugs are fast-tracked to get into our lives. Ideas, not so much. Typically it takes a generation — twenty, twenty-five years — for a new idea to come into acceptance. And the first reaction of any science, medicine included, is to get into denial, which is, “There isn't enough data to support this concept, and I can't be perceived as practicing bad medicine by embracing a concept that isn't proven yet.” But that means that all of their patients are going to have to wait twenty years — until suffering — until that person goes, “Now there's enough evidence, now I can learn how to do this, and now I'll begin to help you.” I'm not wired that way. I'm wired that if I have a suffering person, and I have something that I can offer them that might help, I'm going to try it. I'm going to do it in the safest way I know how, but I can't leave someone dangling for twenty years and say, “I'm sorry, I have to wait until my profession figures out what to do.” That's not me.I worked at the medical school at the University of Minnesota Duluth for eleven years. And I was not only on the faculty, but I was on the committee that determined what new information was put into the curriculum. For example, AIDS was just coming into vogue at that particular point, and it was obvious that we needed to have courses on AIDS for the medical students, because this was big. What a lot of people wouldn't understand is that each department in a medical school fiercely guards its time allotment. Everyone gets a certain number of hours, and they're not open to adding new things or giving up any of their time slots for anything new. And so what I would watch is, as new information came into the medical school, each department fiercely refused to add any new lectures in their department, or give up any of the time that they had to anybody else to add that information. So we're talking about university politics now — this is not even medicine, this is people guarding their turf. And I don't even think that would occur to any consumers, that that would happen like that — well, certainly, why would that happen in a medical school? Well, it's because human beings are responsible for each department, and they guard their own turf. So it's a kind of an insidious process about how new information isn't embraced by the profession, to go into the medical school curriculum.Mold, Lyme, and Long-COVID: The “Big Three”23:15Courtney: I want to come back to what you were saying about inflammation being at the core of chronic illness and complex chronic illness. And when it comes to complex chronic illness, whether it's SIRS or mast cell activation from mold or Lyme, we talk about multiple systems being affected — the central nervous system, gastrointestinal tract, endocrine, skin, just you name it. If the inflammation then is from a source of oxidative stress or a major insult — would you say that mold toxicity is the most common, or would you put Lyme or now even COVID on a par with that, as far as the deepest roots causing the inflammation? Not that the chemicals, metals, and everything else we're being exposed to aren't at play.Neil: In my experience, those three are the biggies — mold toxicity, Lyme with its co-infections, and long-haul COVID. Those are the three most common. Of those, in my experience, mold is the most common, and the one that has to be treated first if you have some or all of them. So, for example, in people who have long-haul COVID or Lyme, often their body will not respond to that treatment optimally until you first get the mold out. So there's a little hierarchy of what we do, in what order. And then within that hierarchy, there's also an order in which we do things for people to respond optimally. So, for example, mold toxicity will trigger — and Lyme and Bartonella will do the same thing — limbic dysfunction, vagal nerve dysfunction, and mast cell activation in most of our patients. Not all, but in most. And the longer they have it, the more likely those things are going to get triggered. Once somebody does not feel safe — and the systems that we have in our body to monitor that safety and to keep us safe are the limbic system, the vagal system, and mast cell activation — we have to get the body safer, or it will not be able to take what you need to take to treat mold or Lyme or long-haul COVID. People will literally shut down — their limbic system will essentially go, “Mm, I see what you're trying to do there, and I can't let you do it, because I'm not sure that's safe.” And it will literally not allow people to do it.The Limbic-Vagal-Mast Cell “Trifecta”25:58Courtney: So with one of those, or a combination of those, on board, these threat mechanisms would be kicked up — mast cell activation, limbic system dysfunction, autonomic nervous system dysfunction. If they look similar, or a timeline isn't easily helping parse out what might be primary, how able do you feel to make the distinction — versus if mold is present, starting there?Neil: If we look at our patient's symptoms, they will point us clearly to whether there's a limbic or vagal or mast cell piece, to be specific. The limbic system's job involves primarily monitoring and regulating and keeping emotion and sensitivity in check. So any symptoms that involve those two things are limbic almost by definition. So on the sensitivity side, if someone describes an increased sensitivity to light, sound, touch, smell, chemicals, EMFs, food — they're already telling me my limbic system is dysfunctional. In some ways it doesn't matter what the cause is; if someone has this increased sensitivity, regardless of the cause, I know we have to treat their limbic system first.On the vagal side, the symptoms would primarily run into symptoms that involve the autonomic nervous system, which would involve things like temperature dysregulation, palpitations, insomnia, POTS, blood pressure dysregulation, or symptoms that involve the gastrointestinal tract, because the vagus nerve controls almost the entire intestinal tract. So any GI symptoms — gas, bloating, distension, reflux, diarrhea, constipation, abdominal pain — again, that would lead me to go, the vagus is involved here. So by listening to my patient's symptoms, I can immediately know what's dysregulated here, and what my first treatment arm will be — to get the limbic and vagal systems back up and running again at a safer level, because otherwise our patients aren't going anywhere. They can do binders and antifungals and antibiotics for Lyme, and they will get worse. Their body will basically go, “I know I might need that, but why are you doing that? I can't even get to a place of safety to respond. I'm on self-preservation mode here.”And in the mast cell category — again, all of the same symptoms that could be mold or Lyme or long-haul COVID could also be mast cell. Again, it's a multi-systemic process. A tip-off, which I find very helpful, is if someone describes a symptom that comes on immediately after eating, sometimes while eating. Nothing causes that kind of reaction that fast except mast cell activation. Allergy — and most people, if they do have some symptom that comes after eating, they're going to be thinking, “It must be what I ate, what did I just eat?” But it's not food allergy, it's mast cell activation. In that context, many of our patients have already observed that they can eat a particular food one day and have a very strong reaction, and the next day, same food, nothing. And they'll go, “That doesn't make sense — if this was allergy, I ought to react the same way every time.” And so that is classical mast cell activation, which fluctuates. So — for the first part of your question — that's what I'm looking for. When I take a history, when I talk with patients, I'm going to really dig into: are they already manifesting symptoms that clearly tell me what we need to do first, to get them safer, so that now they can respond properly to the treatment that will really get at their root cause.Are Some People Born More Vulnerable?30:31Courtney: I know you take deep timelines when you meet with someone, so you're really accounting for a lot. But one of the things that I think about a lot is: who is most vulnerable? Do some of us come into the world already with a vulnerability similar to Elaine Aron's highly sensitive person model? And then maybe there's trauma, early attachment disruption — and already vulnerabilities — but then the toxic load that we're all experiencing. But then something like mold or Lyme then hits. And then, all the years and all the patients you've seen — I'm curious how many you feel already had sort of a vulnerability. Not that they ever had to really become sick necessarily, but already had a vulnerability.Neil: Honestly, I would say most. Our limbic system evolves from the time we were in our mother's uterus, so that almost no one has had a perfect childhood. And so whatever someone has had to deal with in childhood — it could be recurrent ear infections or throat infections, or it could be a surgical procedure, or it could be parents, both of whom worked and they didn't get enough time, or they could be abusive parents, sexually, physically, verbally abusive — whatever someone has been exposed to, that forces their limbic system to have to deal with it. Because that's the job of the limbic system, is to keep you safe. So your limbic system is basically going, “Okay, I'm just a little thing here, what do I need to do to cope with this?” And so their limbic system slowly, inexorably, becomes more and more hypervigilant to protect them. Let's say someone had an alcoholic parent, and they would come home, and you were never sure what their status would be — and so you'd kind of hold yourself back from that, which is, “I've got to see what this person is showing me, is it safe for me to come up and give them a hug, or do I want to hang out in my room for a bit until whatever this is settles down?” That's the beginning of this limbic hypervigilance process. And then it just goes on through life. So that if you've had difficult relationships, or surgeries, or severe infections, or anything in the physical or emotional or spiritual plane, a betrayal of some type — the limbic system becomes slowly more and more and more hypervigilant, when the straw hits the camel's back. And that straw could be COVID, or Lyme, or mold toxicity, or another infection of some type — that's the straw that breaks the camel's back. At that point the limbic system goes into shutdown, which — we know the vagal system goes into shutdown, literally, that's something the vagal system is trained to do. It's “okay, we are so unsafe that I'm shutting down my systems here.” And so that predisposes to illness. But I want to tie that back to inflammation, which — a lot of people don't understand that the vagus nerve, for example, controls inflammation in the body also. There are branches of the vagus that go to the spleen, to the gut-associated lymphoid tissue, and to the thymus, all of which are major immune organs. And if the vagus is dysfunctional, inflammation can rage out of control. So again, this comes back to understanding this complexity of inflammation, and how we need to both understand it and know where it is we want to look to get at that inflammation. So there is a profound interconnected limbic-vagal-mast cell piece. Each totally connects to the other. There's an interaction between the thousand biochemical mediators that mast cells make and the nervous system itself. So I call this interconnection the trifecta, which is: you can't just treat the limbic system in a vacuum, because if you're not also looking at the vagal and mast cell system, your treatment may be a little bit helpful, or it might not even work at all, until you combine all three — so that you really understand this is a package deal here, in terms of how we work with it.There was one more piece I wanted to add, Courtney, to understanding the inflammation piece: whether or not someone gets mold toxicity or Lyme or COVID depends on how robust their immune system is. So you could have a family living in a moldy environment — one person is really sick, several are a little bit sick, and one is not sick at all. And the one who's not sick at all can easily go, “I'm not sure what's wrong with you all, but I'm fine in this environment, it can't be my environment because I'm fine.” And what they're not understanding is: yes, they are fine, as long as their immune system stays robust. For the others, they were at risk for all of these conditions because their immune system took a hit. And for many people who were living in a moldy environment, during COVID, for example, when we isolated and people were spending twenty-four hours in their home rather than the eight hours out, they were many now being exposed to more mold at home than they were before. I don't think people began to think about that or look at that. So in that environment, whether or not they were affected depends on the hit they took. Now, the things that will hit an immune system to weaken it, and allow whatever's there to manifest, are: COVID was a biggie, any severe infection, a surgical procedure, childbirth, menopause, or any emotional upheaval will weaken that immune system, and then the immune system loses containment, and now we are off to the races. So what I try to convince people who are living in a moldy environment who are well is that they're living with a ticking time bomb. Should they take an immune hit, they will be just as sick as their family member who they're kind of lording it over, which is, “I'm not sick, what's wrong with you?” You'll be right there yourself if you take that hit — to try to help them understand, yeah, you're okay for now, but once your immune system weakens. So I'm trying to tie together the immune system, its ability to regulate inflammation, and this whole process here.Courtney: Right, right. Which I guess is why we call it complex, complex illness.Neil: It is the way human beings are. We're not making up a new word of complex illness — illness was always complex. We're just beginning to understand how complex it always has been.The Limits of Treating Symptoms Alone44:39Courtney: Right, so there's communities out there addressing mast cell activation. There's communities out there addressing POTS and dysautonomia. Communities out there addressing OCD and more obvious limbic-type issues. And then there's the whole mental health field. And the dots aren't getting connected. I mean, I've yet to see someone with OCD — I think it's like eighty to ninety-five percent have mold toxicity as part of the picture.Neil: You know, an example — and I won't name names — is there's an eminent pediatric physician who is very well known for his work in autism, who thought he was ADD his whole life until he recognized that he had mold toxicity and started taking antifungals, and all of a sudden his brain went online and he doesn't have it anymore. So that's just a very clear example of what you're talking about. And what we are talking about is: it's absolutely essential that all people who work in the medical field, all healthcare providers, embrace this complexity, because if you're only working on a piece of it, you will help some people to a certain extent, but you will not help people optimally. I mean, that is the absolute bottom line.The understanding that mast cell activation was huge came in 2016, when Larry Afrin wrote his book, Never Bet Against Occam. It was a huge game changer. When I read his book, it was like, “My goodness, I've been missing this in my patients.” And the whole world embraced this information, so that every medical center in the country now has a mast cell activation clinic. However, they're looking at it as a single thing with a label to it, and they're treating it just that way. They have not recognized that if they don't add limbic and vagal work to it, their treatment is not going to be adequate. And so, yes, they're helping people, but absolutely not optimally. And to make it worse, very few of those clinics have recognized that what's causing mast cell activation, which absolutely needs to be treated, is mold toxicity and Lyme. So people go to these clinics and get a certain amount of help, but they're not being treated comprehensively, which is a pet peeve of mine — which is, come on, if you're going to have a clinic, understand the whole interactions of whatever name it is you're working with. If you're going to be an ENT specialist, understand everything that impacts that area. If you're going to be a cardiologist, understand everything that impacts it. And we just don't see that. We see people kind of in their little box — “No, no, I've learned this, this is what I do, this is how I work” — and it's just unfortunate that they're not looking at the bigger picture.Courtney: Right, I think add to that PANS and PANDAS, because in psychiatry, people feel like they're deep diving because they're getting to PANS and PANDAS. It's like, okay, you've got to go deeper than that, because even those conferences, they talk about the need for treating relapse, and it's just going to keep reoccurring.Neil: I mean, they're using IVIG to help. That's nice, but they're not getting to cause. And we know when PANS and PANDAS first emerged on the scene, it was all about strep, and that was the focus for a long time. But as time emerged, it was very clear that this was a neurological inflammation triggered — here we go, broken record — Lyme, mold, other infectious agents had to be looked for. And if we treated those, you could cure PANS. It wasn't something that needed IVIG for the rest of your earthly life.Courtney: Even among those, would you say very often mold is underlying the mycoplasma, the candida?Neil: I think mold is one of the most missed components to illness that I can think of. If I have a goal in life, it would be to raise the consciousness of our profession as to the importance of mold toxicity, how common it is. We're talking millions and millions of people who are not diagnosed, because their doctors don't know about it, and therefore are not making the diagnosis. I'd love to see the consciousness get to the point that someone would present with these complicated stories and a doctor would say, “Why don't we think about mold toxicity?” That would be the most important thing I would have done in my career.Courtney: Yeah, well, you're certainly raising awareness.Neil: I'm working — it is slow. As we said, I'm working on a twenty-year generational issue here.Courtney: You've mentioned that the underlying source needs to be addressed, but the nervous system and immune systems need to be addressed. So one of the things that comes up with limbic system retraining is: I've had people hear the message that if they just address their limbic and autonomic nervous system, then they wouldn't need to address what I see as an ongoing threat, such as a mold toxin. So I'm hoping you can speak to that, and the importance of these programs, despite that.Neil: Sure. A couple of the better-known limbic retraining programs, the coaches get a little bit zealous about — “limbic retraining is so important, this is all you need to do alone, don't even do anything else, just do limbic retraining.” And I suspect that there are a handful, very few, but a handful of people who've gotten well just doing limbic retraining. If, for example, if you had mold toxicity, if it was relatively new, if you had not colonized, and you moved out of your mold exposure soon, it is possible that the limbic retraining would help reboot it to the point that your immune system rebooted itself and you'd be fine. I believe there are a few people like that. The vast majority of people who have limbic dysfunction — you need to do limbic retraining and vagal retraining. You may also need to do mast cell retraining, and please look for the cause of that. Those are downstream effects, those are not named diagnoses that you treat alone and it fixes it. Please look for at least mold and Lyme, which are the two most common things that are triggering this at this point. And people are getting the wrong message if they think they need to do it in a vacuum. To make it worse, they're being told, “No, no, just do limbic retraining, that's all you need.” And the truth is, no, you need to combine limbic retraining and vagal rebooting and mast cell activation most of the time. And of course you've got to get back to cause.Courtney: Right, I mean I try to liken it to — if they were in an abusive relationship or toxic relationship, they wouldn't just limbic-system their way out of that, if there was an external threat.Biochemical Contributors47:35Neil: No, you've got to fix what's primary here. I want to add to this discussion — we're focusing on inflammation from toxins and infections, but there are also other biochemical issues, some of them downstream, that need to be looked for and addressed in order for people to recover completely. So, for example, Lyme and mold will trigger kryptopyrrole issues, or imbalances in the ratio between zinc and copper, or they'll trigger methylation issues super commonly. And I just wanted to expand this discussion — I know it's complicated enough, but I don't want to oversimplify it either — that there are other biochemical things that we want to be looking for, because they're treatable, and they will help people to heal faster, if we're also addressing methylation, the need for zinc, the need for magnesium or B6 — those are common components of this whole process here. And so I just want to kind of tie that all together for a moment.Courtney: No, I'm glad you did, because those are topics that I talk about here, so it's important to connect those. The other thing I see, because I integrate the Walsh approaches with treating people that have complex health issues, is zinc seems so amazing when it comes to mast cell activation — making sure that's optimized. As well as connective tissue — and that was something else I wanted to ask you about — is structural issues that can be impacting the autonomic nervous system. I just see a lot of people — I inquire about it because I had it myself — but who have upper cervical instability as part of this whole picture.Structural Contributors49:26Neil: Again, all of these things are interrelated, and the physical structure can prevent people from moving forward in several different ways. One is the structure of the jaw and the face — the body puts a priority on teeth occluding properly. And if the teeth don't meet just quite right, and the jaw is a little bit out of structure, people often talk about TMJ — the body basically freaks out, it goes into sympathetic overdrive. And for some patients — it's not common, but I've seen several dozen — where the jaw had to be realigned by a combination of dentists specially trained in this work, working with osteopathic physicians, to realign the jaw. Often in those patients, they couldn't respond to the limbic and vagal treatment until their jaw got realigned.Same thing is true with what you're talking about, as cervical cranial instability, which is basically a weakening of the ligaments at the base of the skull, where it attaches to the first cervical vertebra. Now, these are all again intertwined — for example, it begs the question of what weakens those ligaments. And the answer is: if you have mast cell activation, some of the materials that the mast cell makes weakens the ligaments. So the ligaments get weak, and where the skull attaches to the first cervical vertebra, instead of being pulled apart, like ligaments do, it collapses. And that influences the blood flow to the brain, the nerve flow to the brain. And again, the body recognizes that as a priority, and often you can't get that better — you can't get limbic and vagal response until that gets fixed.So there are a bunch of structural issues that also need to be looked at, when people become overly sensitive and are not responding properly. And there's more in that area. So, for example, there's a chapter by Tasha Turzo, who's an expert on the jaw structure. There's a chapter in there by Andy Maxwell on cervical cranial instability. So that book would give people a really good overview of how complicated things are, and they might, chapter by chapter, get a clue of, “I haven't looked at this piece yet.” I mean, we haven't talked about oxalate or salicylate imbalances, which can add to that. So I just think that is a resource for folks that could really help them understand how they've gotten where they are, and understand the path out.Courtney: Right, right, because not everyone has all of these areas, but certainly could be held back or have a unique something that they could be getting relief from early on in the process. So I think it's both, to the degree that people are able to learn, and your book Toxic, too — it's like an encyclopedia, even if someone doesn't read straight through it, they can go to the mast cell section, or they can go to the Bartonella section.Neil: It was intended to be a readable way to understand this complexity, because it basically will talk about almost everything we've talked about today, and help people to get better understanding. I mean, we've talked about the bigger picture today. We didn't talk about, okay, how do you diagnose Lyme, how do you diagnose mold toxicity, how do you diagnose long-haul COVID, and most important, because this is very complicated, how do you decide which of those is the biggest player that you want to address first?Distinguishing Between Mold, Lyme & Long-COVID53:58Courtney: Right, I have shared resources on diagnosing mold toxicity. Would you comment on your last point — how do you recognize, are you using specific testing that you want to reference, the RealTime?Neil: I do. But I would emphasize, we're taught in medical school that if you really listen to patients, ninety-five percent of the time you will make the diagnosis by history alone. And I don't want to get too focused on testing, because listening to the patient and having them describe in detail what they're going through will really give you the little pieces you need to tease it apart to a certain degree. That's only possible to a certain degree, because there's a huge overlap between the symptoms of Lyme and Bartonella and mold and long-haul COVID and mast cell activation. Huge overlap. So there's little teeny pieces that will tend to lean more in one way than another. And honestly, that's what's required from all of us, literally years of study, to really get a handle on — someone will say something, okay, that's much more of a mold symptom than it is a Lyme symptom, something else. So I do encourage people, if they think they might have mold, to get a urine mycotoxin test. That has revolutionized our ability to make these diagnoses.Courtney: Would you still set RealTime as the preferred? That's what I've communicated to this audience.Neil: I would. Any test can help make the diagnosis, but for follow-up testing, the only one that's been really consistent is RealTime. And you want a follow-up test, so you want to know what your baseline starting is, and then you want to know, okay, am I getting these toxins out of my body? From my perspective, you know that you're done treating it when that RealTime comes back reading not present in every category. We have better tests now for Lyme than we've had in the past. Years ago, our tests were inadequate to say the least. And the CDC recognized years ago that the tests were so inadequate that it was basically a diagnosis made by a physician by examining all of the history and information that you had. That was enough — you didn't need a lab report to make the diagnosis of Lyme disease. A new test that I'm particularly fond of is Bruce Patterson's fourteen-panel cytokine test. This is a test that measures cytokines, which are the molecules of inflammation — cytokines are made by your immune system to deal with, or fight, different inflammational causes. And so what Dr. Patterson has discovered is there's a pattern of cytokines that we see with long-haul COVID, which is different than the pattern we see for Lyme. And I'm working with him now on the pattern for mold. So we can literally look at that test and look at, okay, what is inflaming this person primarily now, because I'm looking at that inflammational pattern, and I can literally read that. Some of my patients will have all of those on a particular test, or only one, but it really helps tease apart what is — I call it public enemy number one for my patient, what do I need to address as root cause right now. So our science is improving as we go here.A Message of Hope — and Where to Learn More58:49Courtney: And that's huge. Before we go — I think all of your books, but I'm thinking specifically about Toxic and The Sensitive Patient — all the information you generously share gives people a lot of hope who've been struggling out there. And I think your mentoring and teaching so many of us helps extend some of that reach. Is there anything you'd want to convey to people out there in the throes of chronic illness who are feeling hopeless and not getting the feedback from their doctors that this is something they can get beyond?Neil: Sure. My take-home message is always: everything we talked about today is treatable. Is there hope in there? You bet there is. But if you are not getting the help you need from whoever you are seeing, find someone who understands these things. For example, I do have on my website a list of physicians that I've trained over the years that I'm comfortable that they really know what they're doing — it's a growing list. There's someone like Courtney, who's been trained for years to do this, she's good at it. Find someone who knows what they're talking about, so that you can get someone who does embrace this complexity, and will look at it in its entirety, and then get you moving in the right direction, doing the right things in the right order. To me, this can be done. I mean, I have personally helped to cure four or five thousand people with mold toxicity, and an equal number of people with Lyme disease. So we can help the vast majority of people that we're seeing. So, regardless of how long you've been sick, if you haven't been properly diagnosed and you haven't gotten the right treatment, you can be helped.Courtney: Right, right, that's great. And for physicians out there who are interested in learning more about complex chronic illness — are there resources you would point to? I'll be sharing your books, because I think those are great references — but also how people can find what you're doing currently.Neil: Sure, my books — particularly with this discussion, Toxic and The Sensitive Patient's Healing Guide would be the two most appropriate. I would add that I have just finished writing a book on this whole subject of inflammation. It's currently being edited, I hope it'll be out by early next year. So if you stay tuned to my website, I'll let people know when that's going to be available. And I think, Courtney, what you're referring to is: I do have a mentorship program for healthcare providers. We now have three hundred and fifty-plus people in the mentorship program, it keeps growing. You were in one of the first groups — we started with eight, and then people kept wanting to get in on it. So we welcome people to join. If you go to my website, which is simply neilnathanmd.com, there's a whole thing which talks about the mentorship and how to sign up for it. So I certainly welcome people who want to learn more.Courtney: And then you offer consultations and professional consultations also?Neil: I do. My consultations — I am, at this point, since I'm semi-retired, not seeing people directly. But I do offer consultations with a patient and their primary treating physician — so we all get on a Zoom together, and we will go over the details of that person's history and their lab work, and I will help outline a treatment program that looks to me like it will get people well. And actually, Courtney, I actually do a lot of that — I'm not really retired, my wife will tell you. I stay pretty busy. I love helping people. I love being able to take this complicated information and tease it apart, so that I can help people to understand what they need to do, in what order, in order to get better.Courtney: And we're all grateful — grateful that you've followed your path, because so many people have benefited personally and professionally. So thank you for bringing your wisdom and expertise, really appreciate it.Neil: You're very welcome, happy to do that.You can find Dr. Nathan's information, consultations, and mentoring program through his website at neilnathanmd.com. If you'd like to help get this information out into the world, please consider liking, sharing, or commenting.Until next time,CourtneyCourtney Snyder MDDr. Courtney Snyder MD is a holistic, functional, and environmental psychiatrist for children and adults. Find her at courtneysnydermd.com and on the Holistic Psychiatry Podcast on all major platforms.Medical DisclaimerThis podcast is for educational purposes only and is not intended or implied to be a substitute for professional medical advice, diagnosis, or treatment. Consult your own physician for any medical issues you may be having. This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit courtneysnydermd.substack.com

How has HIV care evolved over the past 2 decades? Linda Wesp reflects on lessons from the HIV epidemic, the importance of community partnership, reducing stigma in healthcare, and delivering person-centred care for people living with HIV. Timestamps: 01:03 – The evolution of HIV care 06:23 – Lessons from the AIDS crisis 08:54 - The Wisconsin HIV/AIDS Oral History Project 10:31 – Reducing stigma in healthcare 14:06 – Holistic, patient-centred care 16:22 – Community voices

Curious to learn more about the Triad Method and the impact it has had on the world of homeopathy? Join renowned UK homeopath Hilary Faircloth as she shares her personal journey and the story behind the development of her transformative Triad Method. Hear about her groundbreaking work in Botswana through the Maun Homeopathy Project, where she and a team of more than 40 volunteer homeopaths worked with thousands of people affected by HIV, AIDS, and other complex health challenges. Hilary also shares some of the remarkable stories and outcomes documented in her book, offering a powerful glimpse into the work, dedication, and experiences that shaped this extraordinary project.   Episode Highlights: 02:03 - The turning point: How homeopathy reshaped my perspective 04:19 - A magical accident: How I ended up in Botswana 05:35 - The elephant story 12:35 - Unveiling the African understanding of health and spirituality 19:12 - Introducing the Triad Method: A revolutionary approach to Homeopathy 24:57 - Beyond Remedies: The power of intentions and healing space 27:01 - Healing beyond the physical 28:51 - The birth of the River School of Homeopathy 35:07 - The importance of teamwork   About my guest: Hilary Fairclough is a dedicated homeopath with over 25 years of experience, driven by her profound understanding of the limitations of conventional medicine through her work in the NHS. Witnessing the suffering of individuals with chronic illnesses due to the side effects of conventional treatments, Hilary sought a system of medicine that prioritized holistic well-being and embraced the profound experience of illness. This led her to discover homeopathy, a discipline that resonated deeply with her personal philosophy. After training at the London College of Classical Homeopathy, Hilary became a registered member of the Alliance of Registered Homeopaths, where she upholds their Code of Ethics and engages in regular professional supervision. With a background in sociology and nursing, including specializations in community nursing, palliative cancer care, and bereavement counseling, Hilary brings a wealth of knowledge and expertise to her practice. She founded and directed The Maun Homeopathy Project, a charity providing free homeopathic outreach clinics for people living with HIV and AIDS in Botswana. Hilary's dedication and achievements in the field of homeopathy have been recognized with the Society of Homeopath's "Outstanding Achievement Award." Currently, she divides her time between treating clients and serving as the Assistant Director of the River School of Homeopathy, where she imparts her experience and passion to shape the future generation of homeopathic practitioners. Hilary practices homeopathy as both a science and an art, utilizing her extensive knowledge and intuition to provide personalized and compassionate care to her clients, creating a safe and nurturing space for healing and growth.   Find out more about Hilary Website: https://hilaryfairclough.com/ Email: info@hilaryfairclough.com   To learn more  about the River School of Homeopathy, please visit their website at https://www.riverschoolofhomeopathy.org   If you would like to support the Homeopathy Hangout Podcast, please consider making a donation by visiting www.EugenieKruger.com and click the DONATE button at the top of the site. Every donation about $10 will receive a shout-out on a future episode.   Join my Homeopathy Hangout Podcast Facebook community here: https://www.facebook.com/groups/HelloHomies   Follow me on Instagram https://www.instagram.com/eugeniekrugerhomeopathy/   Here is the link to my free 30-minute Homeopathy@Home online course: https://www.youtube.com/watch?v=vqBUpxO4pZQ&t=438s   Upon completion of the course - and if you live in Australia - you can join my Facebook group for free acute advice (you'll need to answer a couple of questions about the course upon request to join): www.facebook.com/groups/eughom  

What happens when fear and misinformation put the human-animal bond at risk? Dr. Ken Gorczyca joins Dr. Susan Little and Dr. Jolle Kirpensteijn for the 249th & 250th episodes of Purr Podcast to share his extraordinary experience during the AIDS crisis, when immunocompromised people were sometimes advised to give up their pets because of concerns about zoonotic diseases. He explains how veterinarians helped challenge misinformation and establish safer guidelines for immunocompromised pet owners. Today, Dr. Gorczyca works as an at-home end-of-life vet, helping pets and their families navigate saying goodbye in the comfort of their own homes. Join us for a deeply moving conversation about veterinary medicine, compassion, grief, and the extraordinary role pets play in our lives. Thanks for tuning in to the Purr Podcast with Dr. Susan and Dr. Jolle!If you enjoyed today's episode, don't forget to subscribe, rate, and leave us a review—it really helps other cat lovers and vet nerds find the show. Follow us on social media for behind-the-scenes stories, cat trivia, and the occasional bad pun. And remember: every day is better with cats, curiosity, and maybe just a little purring in the background. Until next time—stay curious, stay kind, and give your cats an extra chin scratch from us. The Purr Podcast – where feline medicine meets feline fun.

Frank talks with novelist and creative writing professor April Reynolds about her novel The Shape of Dreams, set in East Harlem during the crack and AIDS epidemics of the 1980s.They discuss the changing experience of publishing and reading books, April's childhood in South Dallas, the role of the Black church, the loss that helped shape the novel, and the difficult experience of writing about a mother whose young son has been murdered.The conversation eventually turns toward the present and what stories can teach us about neighbors, immigrants, community, democracy, and the things we still have in common._____LINKShttps://www.instagram.com/theshapeofdreamsbook/The Shape of Dreamshttps://bookshop.org/a/99692/9780593316863_____I have had the pleasure of talking to some of the leading authors, artists, activists, and change-makers of our time on this podcast, and I want to personally thank you for subscribing, listening, and sharing 100-plus episodes over 100,000 times.Please subscribe to this Podcast, In Conversation… with Frank Schaeffer, on your favorite platform, and to my Substack, It Has to Be Said. Thanks! Every subscription helps create, build, sustain and put voice to this movement for truth. Subscribe to It Has to Be Said. The Gospel of Zip will be released in print and on Amazon Kindle, and as a full video on YouTube and Substack that you can watch or listen to for free.Support the show_____In Conversation… with Frank Schaeffer is a production of the George Bailey Morality in Public Life Fellowship. It is hosted by Frank Schaeffer, author of The Gospel of Zip.Learn more at https://www.thegospelofzip.com/Follow Frank on Substack, Facebook, Twitter, Instagram, Threads, TikTok, and YouTube.https://frankschaeffer.substack.comhttps://www.facebook.com/frank.schaeffer.16https://twitter.com/Frank_Schaefferhttps://www.instagram.com/frank_schaeffer_arthttps://www.threads.net/@frank_schaeffer_arthttps://www.tiktok.com/@frank_schaefferhttps://www.youtube.com/c/FrankSchaefferYouTubeIn Conversation… with Frank Schaeffer Podcast

De que maneira o reconhecimento precoce de lesões no nervo óptico por substâncias tóxicas, a indicação precisa da profilaxia antirrábica e os métodos rápidos de detecção de resistência viral redefinem a conduta clínica? Neste episódio do Afya News, analisamos os alertas do Congresso Brasileiro de Oftalmologia sobre a neuropatia óptica tóxica associada ao consumo crônico de álcool e tabaco, caracterizada por perda visual indolor, central e bilateral, além da gravidade da intoxicação aguda por metanol. Discutimos também o alerta emitido pelo CDC sobre o aumento de atendimentos e erros de manejo na profilaxia pós-exposição (PEP) contra a raiva, destacando a relevância da avaliação imediata e da administração correta de vacina e imunoglobulina. Por fim, apresentamos no Radar a tecnologia apresentada na Conferência Internacional sobre Aids que utiliza um ensaio enzimático para identificar a resistência do HIV a inibidores da transcriptase reversa em cerca de duas horas e com baixo custo de reagentes. O Afya News apresenta notícias da medicina com informação confiável e atualizada no seu tempo. Criado pela Afya, o maior hub de educação e soluções para a prática médica do Brasil, nosso propósito é transformar a saúde junto com quem tem a medicina como vocação.Fontes do episódio aqui:⁠https://portal.afya.com.br/podcasts/afya-news/15-09-2026Conteúdo 100% validado por equipe médica.Médico Responsável: Dr. Guilherme Rodrigues — CRM-RJ 1049461.

In today's episode of Talk Heathen, Christy Powell, Jamie The Blind Limey, and Kelley Laughlin tackle religious trauma, indoctrination, and the question of whether religion causes more harm than good!Anne in CA shares her journey from a large Catholic family to atheism. Growing up, she struggled with contradictions like sins being forgiven yet purgatory and hell still existing. After years of questioning what she truly believed versus what she was told to believe, Anne deconstructed her faith. How do you reconcile doctrines that contradict each other? What happens when you realize fear was the foundation of your belief?Matt in VA argues Christianity does more good than harm, pointing to foreign aid and moral instruction like abstinence preventing AIDS. The hosts challenge his claims with evidence of religious harm and contradictions in his reasoning. Does charity justify institutional cover-ups and anti-science stances? If abstinence-only education fails, why defend it? What moral authority does Christianity actually hold?Thank you for joining us this week! We will see you next time!Become a supporter of this podcast: https://www.spreaker.com/podcast/talk-heathen--3195702/support.

What comes to mind if I say San Francisco–the hippies and Grateful Dead of the 1960’s, the locus of the AIDS epidemic of the 1980’s, the Internet revolution of the 1990’s, the urban decay of the pandemic era or the AI revolution that is clearly upon us?  Well, I think the best answer is all of the above.  The city is a complicated mix of culture, technology, business and a growing class divide.  There may be no better chronicler of the city than Jonathan Weber who has been covering this beat for different media outlets since the early 1990’s.  All of his knowledge and sense of place are married in his great new book, “City on the Edge: Technology, Politics, and the Fight for the Soul of San Francisco.”  He dispels the notion that many of us have had that San Francisco and Silicon Valley are interchangeable.  They are very different places. Both have been crucial to modern-day America.  When you think San Francisco remember that e-publishing, social media, video streaming, cloud software and the sharing economy really came to life there. Enjoy this fascinating conversation.

Connor Trinneer and Dominic Keating -- and special guest, director David Livingston -- watch Star Trek: Enterprise's "Stigma".  It's an early 2000s ambitious AIDS allegory centered on T'Pol, who is facing ostracization from the Vulcan High Command after contracting Pa'nar Syndrome, a neurological condition transmitted solely by a stigmatized minority: those who can mind meld. We follow Archer and Phlox as they fight against systemic prejudice to protect T'Pol's position on the ship. Humanity once again proves itself more tolerant than the Vulcans... *sips tea*Each week in The D-Con Chamber, we boldly revisit Star Trek: Enterprise through behind-the-scenes stories, watch-along commentaries, and conversations with the people whose lives were forever changed by the franchise. Whether they are breaking down classic episodes or welcoming special guests from across the Trek universe and beyond, hosts Dominic Keating and Connor Trinneer mix laughs, insider perspective, and Trek appreciation in every episode.

Seattle wastes millions of taxpayer dollars to aid illegal immigrants. A 67-year-old man was killed in a fight at Westlake Park in Seattle. J.D. Vance fires back at Abdul El-Sayed after the Michigan Senate candidate’s vicious comments about Vance’s grandfather. // LongForm: GUEST: Associate Attorney General Stanley Woodward on the DOJ's lawsuit against the Univeristy of Washington for giving preferential treatment on tuition to illegal immigrants. 

When Freddie Mercury, lead vocalist of Queen and one of the all-time greats of rock music, died from Aids in 1991, he left his beloved Kensington house to his lifelong companion Mary Austin. Once engaged to the superstar – before they both realised he preferred men – Austin was by his side from unglamorous beginnings to global stardom. She exclusively reads the story of their extraordinary relationship for the Story.This podcast was brought to you thanks to the support of readers of The Times and The Sunday Times. Subscribe today: http://thetimes.com/thestoryRead by: Mary AustinProducers: Sophie McNulty and Taryn Siegel.Read More: My life with Freddie Mercury — by the best friend he nearly married We want to hear from you - email: thestory@thetimes.comClips: Live Aid, Queen Youtube. Music Excerpt: Queen - Lily of the Valley (Sony/ATV Music Publishing LLC)Photo: Getty Images.This podcast was brought to you thanks to subscribers of The Times and The Sunday Times. To enjoy unlimited digital access to all our journalism subscribe here. Hosted on Acast. See acast.com/privacy for more information.

Subscribe now for an ad-free experience and all of our episodes. I, for one, welcome our new AI overlords. In this week's news: the EU's Copernicus Climate Change Service confirms last month was tied for the hottest ever recorded (0:52); the Houthis/Ansar Allah take the port city of Mokha (1:45); the U.S. and Iran exchange ship attacks as oil prices rise (5:25); the IAEA refers Iran to the United Nations (7:32); Trump predicts an end to the Iran war immediately after the midterms (8:59); 12 countries ban products made in Israeli settlements (10:52); a new report alleges that Netanyahu ignored October 7 warnings and a chance to recover hostages (13:49); the IDF takes a strategic ridge in Lebanon, then escalates strikes (18:30); an arbitration court rules against India on the Indus Waters Treaty (20:49); new claims of famine emerge in Sudan's Darfur region (23:05); the Nigerian government and Boko Haram maintain a ceasefire (24:59); the Trump administration phases out U.S. support for anti-AIDS programs in Namibia (27:21); American envoys Jared Kushner and Steve Witkoff visit Russia and Ukraine (29:22); Ukraine tries to close Russian airspace (31:20); and in a trade war update, Canadian tariffs on U.S. goods take effect (32:50).          Don't forget Derek's Substack, Foreign Exchanges. Enjoy Danny's new Substack, Imperialist Realism. Learn more about your ad choices. Visit megaphone.fm/adchoices

Talked a lot about AIDS here for some reason, but mainly how did Eazy E get it, we couldn't remember Headlines

I, for one, welcome our new AI overlords. In this week's news: the EU's Copernicus Climate Change Service confirms last month was tied for the hottest ever recorded (0:52); the Houthis/Ansar Allah take the port city of Mokha (1:45); the U.S. and Iran exchange ship attacks as oil prices rise (5:25); the IAEA refers Iran to the United Nations (7:32); Trump predicts an end to the Iran war immediately after the midterms (8:59); 12 countries ban products made in Israeli settlements (10:52); a new report alleges that Netanyahu ignored October 7 warnings and a chance to recover hostages (13:49); the IDF takes a strategic ridge in Lebanon, then escalates strikes (18:30); an arbitration court rules against India on the Indus Waters Treaty (20:49); new claims of famine emerge in Sudan's Darfur region (23:05); the Nigerian government and Boko Haram maintain a ceasefire (24:59); the Trump administration phases out U.S. support for anti-AIDS programs in Namibia (27:21); American envoys Jared Kushner and Steve Witkoff visit Russia and Ukraine (29:22); Ukraine tries to close Russian airspace (31:20); and in a trade war update, Canadian tariffs on U.S. goods take effect (32:50).         Don't forget Derek's Substack, Foreign Exchanges.Enjoy Danny's new Substack, Imperialist Realism.Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Ricky G. started drinking and getting high at just 15 years old after running away from home and finding himself homeless, scared, and searching for somewhere to belong. What began as a way to cope eventually turned into nearly three decades of addiction.  At 22, Ricky landed in the hospital and learned that his HIV had progressed to AIDS. His T-cell count was just three, and doctors told him he had seven days to live. He survived, but instead of changing his life, Ricky eventually found meth, the drug that would consume the next 20 years. By 2020, Ricky was arrested and placed on house arrest at his father's home. Even with a safe place to live and his father taking care of him, he continued using, having drugs delivered to the house and sneaking people through his bedroom window. Then, in 2022, his father died. Ricky spiraled even further, reaching a point where he was considering ending his own life.  Instead, another arrest ultimately led him to treatment. In this episode of Hell Has an Exit, Ricky sits down with Bryan to talk about addiction, homelessness, HIV, losing his father, jail, treatment, finding recovery for the first time, and what finally made him want a different life. Today, Ricky is clean, healthy, active in the recovery community, sponsoring others, and living a life he once couldn't imagine for himself. After spending most of his life either homeless, incarcerated, or high, he celebrated his 45th birthday as the first birthday since age 15 that he was none of those things.  His message to anyone just getting clean is simple: find your people, ask questions, get a sponsor, listen to the suggestions, and keep coming back. Learn more about your ad choices. Visit megaphone.fm/adchoices

At the AIDS 2026 Global AIDS Conference in Rio de Janeiro, Ben interviews Dr. mike Reed about how global health technology succeeds or fails depending less on the tools than on governance, ownership, community co-design, and alignment with ministries of health and other relevant government authorities. Reed contrasts Rwanda's scaled Zipline drone deliveries and a government-led “sovereign” AI large language model and real-time health dashboards with the many HIV AI pilots that never scale due to weak partnerships, poor interoperability, and lack of sustainable financing. They discuss AI's potential to support marginalized communities with stigma-free access to information and care navigation, alongside risks around privacy, market capture by big tech, and the need for fair value exchange when community data trains models. Reed highlights a “force multiplier checklist,” Botswana's youth-designed prevention campaign, and the need to speed up rigorous implementation science and data-to-action timelines. 00:00 Intro 00:32 Drones and donor tech 03:45 Why pilots fail 06:56 Rooting tech locally 10:59 Sovereign AI example 12:43 AI for key populations 18:28 Governance and commons 25:06 Force multiplier checklist 29:36 Data sovereignty rules 31:24 Faster science with AI 36:19 Optimistic closing 41:12 Thanks and wrap Learn more about the book: https://bit.ly/redefining-global-health More from UCSF Institute for Global Health Sciences: https://globalhealthsciences.ucsf.edu Check Out mike Reid's Substack: https://substack.com/@reimaginingglobalhealth Check Out Ben's Substack: https://substack.com/@benplumley1 Join the Conversation! What would it take for global health to avoid decline? Share your thoughts in the comments! Subscribe & Stay Updated: Listen on Spotify, Apple Podcasts, or your favorite podcast platform. Watch on YouTube & subscribe for more in-depth global health — and look out for a dedicated sub channel for Redefining Global Health in the 21st Century under A Shot in the Arm's YouTube home. Redefining Global Health in the 21st Century: The Podcast (Playlist on Youtube) https://bit.ly/rgh-book A Shot in the Arm Podcast Youtube (Main Channel) https://youtube.com/@shotarmpodcast

Sometimes, you go looking for God and end up almost burning down a building.In this second LIVE episode of Unwritten, Mark shares an unbelievable story from a college mission trip to an AIDS hospice in Denver. What started as a desire to serve others and encounter God turned into laughter, late-night cookies, spontaneous combustion, a near disaster, and a realization that God can show up in the moments we least expect.Whether you're searching for God in the big moments or just looking for cookies late at night, this episode is a reminder that He can find you anywhere.JOIN US! At the SEEK27 Conference. Register here. https://bit.ly/4cMLabj

Please enjoy this Summer Salon Series episode of Breaking Form Selects: Marie Howe. Support Breaking Form by reviewing the show on Apple Podcasts here.Aaron's STOP LYING is available from the Pitt Poetry Series. BEAUTIFUL PEOPLE is available from Bridwell Press. James's ROMANTIC COMEDY is available from Four Way Books.  Notes:Marie Howe was born in Rochester, New York in October 1950 (she's a Libra!). She earned an MFA from Columbia University before publishing The Good Thief (1988, chosen by Margaret Atwood for the National Poetry Series); What the Living Do (Norton, 1997), a book that centers other brother John's death from AIDS-related illness; The Kingdom of Ordinary Time (2008); Magdalene (2017); and New and Selected Poems (2024), which was awarded the Pulitzer Prize for Poetry. Howe has received fellowships from the Bunting Institute at Radcliffe College, the National Endowment for the Arts, the Guggenheim Foundation, the Academy of American Poets, and the Fine Arts Work Center in Provincetown. She was the Poet Laureate of New York State from 2012 to 2014. She is the poet in residence at The Cathedral Church of St. John the Divine and a chancellor of the Academy of American Poets. Visit Marie Howe's website: http://www.mariehowe.com/Listen to her talk on Poetry Unbound here and watch her comprehensive interview with Krista Tippett here (90 minutes).You can see her give a reading in 2020 here (27 min); or read her poem "The Gate" from What the Living Do here (1.5 min); or read from her book Magdalene here (~23 min).Read this 1997 interview with Howe conducted by Victoria Redel.

Comedians Jared Freid & Dru Montana join Big Jay Oakerson, Luis J. Gomez, and Steve Rannazzisi to discuss a series of possible "incidents," money for AIDS, the next Skankfest Golden Ticket contest, the Marilyn Manson / Rob Zombie concert, and the Reggie Watts ketamine scandal. All This and More, ONLY on The Most Offensive Podcast on Earth, The LEGION OF SKANKS!!!Original Air Date: 09/01/26Support our sponsors!Visit BodyBrainCoffee.com and use code LOS20 for a limited time to get 20% off your order! #BodyBrainPodGet $10 off at BRUNT with code LEGION at https://www.bruntworkwear.com/LEGION and enter THE BRUNT POTTY OF GOLD SWEEPSTAKES for your chance to win $50,000. No purchase necessary. Ends 9/18/26. Official rules apply. #BruntpodDon't sleep on @ultrapouches. New customers get 15% off with code LEGION at http://takeultra.com #UltraPouchesNew customers get 40% off with code SKANKS at http://GLD.com #GLDSheath. The underwear of legends. Go to https://www.sheath.com/LOS and use code LOS for 20% off. #SheathPod---------------Skankfest X New Orleans badges available at www.skankfest.com!---------------

Jess is joined by downtown New York fixture Gene Fedorko, age 83, for a trip through more than six decades of queer history. Gene recalls escaping to New York City in 1960, discovering Fire Island in 1961, attending the March on Washington in 1963 and moving to Provincetown in 1970. Plus: surviving the AIDS crisis, addiction and alcoholism -- and the fabulous Chelsea loft he still calls home. ⭐ IG: @jessxnyc  ⭐ Jess' docu-series on the history, mystique & lore of Fire Island — Finding Fire Island ⭐ Jess' docu-series on the rise & fall of SoulCycle — Cult of Body & Soul

The greatest mysteries have a shadowy figure at the center—someone who sets things in motion and holds the key to how the story unfolds. In epidemiology, this central character is known as Patient Zero—the case at the heart of an outbreak. This hour, Radiolab digs up an episode we first produced in 2011 and hunts for Patient Zeroes from all over the map. We start with the story of perhaps the most iconic Patient Zero of all time: Typhoid Mary. Then, we dive into a molecular detective story to pinpoint the beginning of the AIDS, and we re-imagine the moment the virus that caused the global pandemic sprang to life. After that, we're left wondering if you can trace the spread of an idea the way you can trace the spread of a disease. In the end, we find ourselves faced with a choice between competing claims about the origin of the high five.  Signup for our newsletter!! It includes short essays, recommendations, and details about other ways to interact with the show. Sign up (https://radiolab.org/newsletter)! Radiolab is supported by listeners like you. Support Radiolab by becoming a member of The Lab (https://members.radiolab.org/) today. Follow our show on Instagram, Twitter and Facebook @radiolab, and share your thoughts with us by emailing radiolab@wnyc.org.Leadership support for Radiolab's science programming is provided by the Simons Foundation and the John Templeton Foundation. Foundational support for Radiolab was provided by the Alfred P. Sloan Foundation. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.