Podcasts about placebos

Special announcement: Rohan is not here. But Drew and Roth do actually have an important announcement.Stuff We Talked AboutMasochistic tendenciesThe Cyber-Christ ComplexOther people's dogsNon-fungible podcastsCredits- Hosts: Drew Magary & David Roth- Producer: Brandon Grugle, Multitude- Editor: Mischa Stanton, Multitude- Production Services & Ads: Multitude- Subscribe to Defector!About The ShowThe Distraction is Defector's flagship podcast about sports (and movies, and art, and sandwiches, and certain coastal states) from longtime writers Drew Magary and David Roth. Every week, Drew and Roth tackle subjects, both serious and impossibly stupid, with a parade of guests from around the world of sports and media joining in the fun! Roth and Drew also field Funbag questions from Defector readers, answer listener voicemails, and get upset about the number of people who use speakerphone while in a public bathroom stall. This is a show where everything matters, because everyone could use a Distraction. Head to defector.com for more info.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Most of us hear placebo and assume we're being fooled. Tami thought so too. Then Shamini Jain — clinical psychologist, biofield scientist, and author of Healing Ourselves — told her the placebo effect is actually our own healing response at work. You don't have to be tricked to get better. Mallory and Chris have spent the past year and a half working on a podcast about energy healing (Phenomena) and Sounds True is offering—right now—an immersion course on energy healing featuring Shamini Jain as well as Robert Peng and Laurie Nealon…so now felt like the perfect time to bring this conversation back. And maybe rename that elephant for good.Taken from the full Insights at the Edge conversation with Shamini Jain.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this solo episode, I explore something I see again and again on the fertility path. The moment a label gets attached to your body, something shifts. A word from a doctor, a number on a lab report, a diagnosis. Suddenly you are not just living in your body, you are living inside the story you were handed about it. We look at two powerful words. Placebo, where belief in a treatment creates real, measurable improvement, and its lesser known shadow, nocebo, where a negative expectation produces real, measurable harm. Drawing on a body of research, including a large meta-analysis of more than eight thousand people and the well-known work on how labeling shapes outcomes, I unpack how the words we hear, and the words we tell ourselves, land in the body in ways we can measure. Then I bring this home to fertility. The labels so many women carry, from diminished ovarian reserve to advanced maternal age to hostile uterus, carry a second emotional and physiological payload that almost no one warns you about. I share the Chinese medicine view of the Bao Mai, the channel connecting the heart to the uterus, and how what lands in the heart reaches the womb. This is the same truth that modern nocebo research is only now naming. This is not about positive thinking on command, and it is never about blame. It is about gently taking back authorship of the story your body lives inside. I close with grounded ways to separate the data from the story, soften the language you carry, and protect your inner environment in this tender season. Key Takeaways: The placebo effect is well known, but its shadow, the nocebo effect, is just as real. A negative expectation alone can produce genuine physical symptoms, not imagined ones. A 2023 meta-analysis of 130 studies and more than 8,000 people found a reliable, medium sized nocebo effect across many health outcomes. The expectation of harm was enough to create the experience of harm. Labels carry power. Research shows that simply being told a medication was a cheaper generic, with nothing else changed, led more people to report side effects and feel it worked less well. The body responds to the label, not only the substance. Belief can heal as well as harm. In the Crum and Langer hotel maids study, women who were simply told their daily work counted as exercise showed real drops in weight, blood pressure, and body fat, with no change in behavior. On the fertility path, clinical labels carry a hidden emotional and physiological payload. The reproductive system is highly sensitive to the nervous system, and a frightening label can quietly feed a fear and stress loop. Chinese medicine has described this for thousands of years through the Bao Mai, the heart to uterus channel. When the heart is calm, the message reaches the womb. When the heart is in distress, the womb feels it. What lands in the heart reaches the body. This is never about blame or forcing positivity. It is about reclaiming authorship. Separate the data from the story, question the language you have absorbed, protect your inner environment, and cultivate genuine calm. About the Host: Michelle Oravitz is a fertility acupuncturist, Ayurvedic practitioner, ABORM Fellow, and host of The Wholesome Fertility Podcast. She is the author of The Way of Fertility and the founder of The Wholesome Lotus. Michelle blends modern fertility science with the wisdom of Traditional Chinese Medicine and Ayurveda, helping women understand their bodies as intelligent and responsive rather than broken. Her work centers on nervous system regulation, root cause healing, and the deep connection between the mind, the heart, and fertility. Disclaimer: The information shared on this podcast is for educational and informational purposes only and is not intended as medical advice. Please consult with your healthcare provider before making any changes to your health or fertility care. Ready to discover what your body needs most on your fertility journey? Take the personalized quiz inside The Wholesome Fertility Journey and get tailored resources to meet you exactly where you are: https://www.michelleoravitz.com/the-wholesome-fertility-journey For more about my work and offerings, visit: www.michelleoravitz.com Curious about ancient wisdom for fertility? Grab my book The Way of Fertility: https://www.michelleoravitz.com/thewayoffertility Join the Wholesome Fertility Facebook Group for free resources & community support: https://www.facebook.com/groups/2149554308396504/ Connect with me on social: Instagram: @thewholesomelotusfertility Facebook: The Wholesome Lotus Featured in this episode, my Fertility Affirmations Ebook, a gentle, grounded way to begin offering your body kinder and truer words: https://www.michelleoravitz.com/fertilityebook  

Charlie Goldsmith, known to many as The Healer from the TLC series, joins Andrea for a conversation that goes far beyond his extraordinary results. While Charlie first became widely known for the remarkable ways he could alleviate pain and other conditions, his deeper mission is now focused on a larger problem: how to identify genuine healing ability, study it responsibly, and make real help easier to find for the people who need it most. As the conversation moves through Charlie's unexpected discovery of his ability, the resistance surrounding energy healing, the challenges of research, and the platform he is now building, the episode opens into something much larger than one healer's story. It is about evidence, access, human potential, and what it might take for healing ability to be taken seriously without losing what makes it extraordinary.  Find out how Charlie's free app is designed to identify genuine healing ability, connect people in need with those healers, and generate data that could shape the future of energy healing research. This mission needs people like you now. ✨ Learn more about Charlie Goldsmith: https://charliegoldsmith.com/Recorded: May 25th, 2026Episode Highlights: 00:00 - Limits Of Understanding00:52 -  Meet Charlie Goldsmith02:50 - Energy Awakening At 1806:11 - First Healing Moment09:45 - Mission To Prove It14:29 - Identity And Judgment17:40 - How The TV Show Happened22:06 - Why Media Stayed Closed24:39 - History Of Healing Backlash28:31 - Placebo Nocebo Debate31:58 - Placebo as Medicine33:31 - Challenging the Skeptics36:17 - What He Can Heal40:18 - Limits and Success Rates41:31 - The App Study Protocol47:33 - Why AI Makes It Safe51:24 - How to Use The Ennie App54:06 - Affordable Access Mission58:15 - Join the Collective Effort01:01:39 - Final Thanks and Follow Us!Channel Your Divine Self, a twelve-week live course where you build a direct, grounded relationship with your own inner guidance, alongside the Emissaries of Light. The waitlist is open now, and you'll be the first to know when registration begins. Join the waitlist: https://mainstream-reiki.kit.com/cydswaitlistAndrea's Links: https://beacons.ai/andrea_kennedyAndrea's Reiki Business Success Course:https://www.mainstreamreiki.com/reiki-business-success-courseVisit our websiteVisit our Amazon Shop  Sponsored by The Mainstream Reiki Community https://members.mainstreamreiki.com/HealthyLine offers revolutionary PEMF  and far-infrared mats. Get 10% off and free shipping in the continental US with code "Mainstream10FS". What Resonates? is produced by Twisted Spur MediaAndrea may earn money through Amazon for qualifying purchases.Disclaimer: The views and opinions expressed in this program do not  reflect those of the podcast or anyone affiliated with its production. This program is presented for entertainment purposes only. The utilization of the information provided is at the listener's own discretion.

Rückenschmerzen oder Migräne ohne körperliche Ursache? Oft ist ein überaktives Alarmsystem im Gehirn schuld. Wir sprechen in dieser Achtsam über die Pain Reprocessing Therapy (PRT). Kann man Schmerzen lindern, indem man das Gehirn trainiert?**********An dieser Stelle findet ihr die Übung:34:57 - Übung: Geleitete Meditation zu "Somatic tracking"**********Quellen aus der Folge:Ashar, Y. K., Gordon, A., Schubiner, H., Uipi, C., Knight, K., Anderson, Z., ... & Wager, T. D. (2022). Effect of pain reprocessing therapy vs placebo and usual care for patients with chronic back pain: a randomized clinical trial. JAMA psychiatry, 79(1), 13-23. Ashar, Y. K., Low, E. L., Knight, K., Schubiner, H., Gordon, A., LeRoux, A., ... & Wager, T. D. (2025). Pain Reprocessing Therapy vs Placebo and Usual Care for Patients With Chronic Back Pain: 5-Year Follow-Up of a Randomized Clinical Trial. JAMA psychiatry, 82(10), 1049-1051. Gordon, A., & Ziv, A. (2023). Wege aus dem Schmerz: der bahnbrechende, wissenschaftlich bewährte Ansatz zur Heilung chronischer Schmerzen. Unimedica. **********Hörtipp:Die Lösung - der Psychologie-Podcast | BR**********Den Artikel zum Stück findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .**********Ihr habt Anregungen, Ideen, Themenwünsche? Dann schreibt uns gern unter achtsam@deutschlandfunknova.de

For decades, women have been told that hormone replacement therapy causes breast cancer, but where did that message come from, and is it the full story? In this episode, Mary Alice Haney is joined by former SheMD executive producer and award-winning storyteller, Ami Armstrong, to unpack the Women's Health Initiative, the landmark study that changed the course of menopause care for an entire generation. Together, they explore how one of the largest women's health studies ever conducted became one of the most misunderstood, and why many experts are working to correct the narrative today.Mary Alice and Ami break down the difference between relative and absolute risk, discuss how media headlines fueled decades of fear around hormone therapy, and explain what today's research says about menopause treatment. They also examine why women have historically been left out of medical research, the importance of personalized healthcare, and how understanding your own risks can empower you to make informed decisions alongside your doctor.Subscribe to SHE MD Podcast for expert tips on PCOS, endometriosis, fertility, hormonal balance, mental health, and more. Share with friends and visit SHE MD website and Ovii for research-backed resources, holistic health strategies, and expert guidance on women's health and well-being.SponsorsK'chava: Treat yourself to a childhood favorite. Go to kachava.com and use code SheMD for 15% off your first order. Midi Health: Book your first virtual visit today at joinmidi.com. Babel: Right now, Babbel is offering listeners up to 60% off. Go to babbel.com/shemd. Rules and restrictions may apply. Osea: Get 10% off your first order sitewide with code SheMD at oseamalibu.com. Cash App: Parents and legal guardians can open a managed account for kids aged six through 12. Visit cash.app/legal/podcast for full disclosures. Opill: Opill is birth control in your control. Check out Opill to see if it is right for you. You can find Opill at most major retailers in store and online at opill.com. What You'll LearnWhy the Women's Health Initiative became one of the most influential and controversial studies in women's health.The difference between relative risk and absolute risk, and why that distinction matters.How media coverage dramatically changed public perception of hormone replacement therapy.Why today's menopause hormone therapy differs from what was studied in the original trial.How women were historically excluded from clinical research and how that affected medical care.What current evidence says about the timing of hormone therapy and menopause treatment.Why understanding your personal health risks leads to better conversations with your doctor.Key Timestamps00:00 Welcome Ami Armstrong02:57 Ami's own HRT journey & why she made this series05:04 The idea behind "It's Not a Purse" (Magritte inspiration)07:43 "Feminine Forever" and the history of estrogen marketing09:02 Why Ami dug into the Women's Health Initiative11:48 Getting women into clinical trials: the 1990s shift18:43 Placebo, estrogen-only & estrogen+progestin arms20:15 What hormones were actually used in the WHI22:04 The timing hypothesis explained23:14 Inside the July 2002 press conference decision24:53 Breaking down the breast cancer numbers (absolute vs. relative risk)27:06 Why the trial was stopped early & the estrogen-only results32:07 HRT use plummets & what hot flashes really mean35:42 The researchers who fought back42:32 Individualized risk & questioning the headlinesKey TakeawaysThe Women's Health Initiative began as an ambitious effort to better understand disease prevention in postmenopausal women but became defined by a controversial 2002 announcement that dramatically changed hormone therapy use.Headlines focused on relative risk increases without explaining the much smaller absolute risk, creating lasting public fear around HRT.The hormone formulations used in the original study are different from many of today's commonly prescribed bioidentical therapies.Experts now recognize that the timing of hormone therapy initiation plays an important role in determining benefits and risks.Women have historically been underrepresented in clinical research, leading to gaps in medical knowledge that continue to impact healthcare today.Every woman's health decisions should be individualized, based on current evidence, personal risk factors, and informed conversations with qualified healthcare providers, not fear-driven headlines.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Refrescamos nuestras playlists con nuevos lanzamientos en el #4x4 de radio @rockaxisoficial. Escuchamos #TheStrokes, #JackWhite, #Adelaida y #Placebo. Lunes 10 y 22 Hrs en Rockaxis.Fm / Conduce @PabloCerda1

What if your beliefs could impact your healing just as much as medicine?

Pflückroboter bei der Apfelernte +++ Wie Extremhitze die Stadtnatur an ihre Grenzen bringt +++ Die chinesisch-russische Grenze im Wandel der Zeit +++ Die unterschiedlichen Mechanismen hinter Placebo-Effekten +++ Die Venus ist aktiver als gedacht

Ever wondered if the placebo effect is actually real—or just “woo-woo” hype? In this special encore episode of Better Than Fine, host Darlene Marshall dives deep into the science, ethics, and real-world value of the much-maligned placebo effect.

Tamsulosin Deprescribing for Lower Urinary Tract Symptoms in Older Men A Randomized Clinical Trial* Side Effect Patterns in a Crossover Trial of Statin, Placebo, and No TreatmentCost-Effectiveness of Fecal Immunochemical Testing Alone vs Co-Testing With Helicobacter pylori Stool Antigen This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

Is simply *believing* that something makes you faster all you need for a better performance outcome?  Enter the Placebo Effect.  In this episode, we explore how expectation influences endurance, why even just tasting a gel makes you faster, and how your mindset can change everything from pain perception to pacing and fatigue. We'll also discuss the flip side—the nocebo effect—and how negative beliefs can sabotage performance before the race even begins. Whether it's the same socks for every marathon, a new pair of "super shoes," a pre-race ritual, or a supplement you take, the placebo effect IS real, but it also proved that mindset is everything.  Have a listen! 

In 1979, Howard Pittman, former policeman and subsequent Baptist minister, suffered a medical emergency and was clinically dead for fifteen minutes. While dead, he was tempted by Satan. Upon rejecting Satan's advances, angels took Pittman on a tour of Second Heaven, kind of like a double of our world, but full of demons. He also got to talk to God (unimpressed with Pittman's life).Pittman's journey was detailed in his 1999 book, Placebo. As many people who read and enjoyed Placebo wished to know more about the demons Pittman encountered, he wrote Demons: an Eyewitness Account, where he gives much (much!) more information about all the demons he saw, including demonic power hierarchies, physical descriptions, behavioural descriptions, and more. Fun book!Big thanks again to Capitalisimo for being the new BCFH co-host. It's so much better having a regular person to talk to on the show.VERY IMPORTANT INFORMATIONI (Jack) will be attending a reading in Melbourne on the 21st of August, at the Bar Lingo, Thornbury, alongside Felix McNamara, Matt Sini, Liam Blackford, Lucas Smith, Jack Norman, Russell Walter, Ivan Niccolai, and some special guests! Please, come along!Contact: jack.bcfh@gmail.comJack has an upcoming novel called 'Audience Capture', out October 2026 through Bonfire Books! Preorder now! https://bonfirebooks.org/product/audience-capture-by-jack-cuthbertson-pre-order/Ko-fi: https://ko-fi.com/bookclubfromhellOur Patreon: www.patreon.com/TheBookClubfromHellJack's Substack: jackbc.substack.comJoin our Discord (the best place to interact with us): discord.gg/ZMtDJ9HscrWatch us on YouTube: https://www.youtube.com/channel/UC0n7r1ZTpsUw5exoYxb4aKA/featuredX: @bookclubhell666Jack on X: @supersquat1Capitalisimo on X: @thecapitalisimoArt by moog

October Event Tickets Sold Here: https://deependtv.com/eventsGo Deeper on Topics From the Showhttp://www.novosnetwork.com/kairosDeep End Websitehttps://deependtv.com/Get Weekly UpdatesText "TAW" to 615-845-5977@Taylor's Websitehttps://taylorawelch.com/Twitter: https://twitter.com/taylorawelchInstagram: https://www.instagram.com/@taylorawelchFacebook: https://www.facebook.com/taylorawelchprofileTikTok: https://www.tiktok.com/@taylorawelchFull Deep End Playlist: https://youtube.com/playlist?list=PLsJLC9JVAX745VhRtK7BsoBWKXF0yVrsB&si=YqkT8lg5eFell2o3Listen to The Deep EndApple Podcasts: https://podcasts.apple.com/us/podcast/the-deep-end-w-taylor-welch/id1500492987Spotify: https://open.spotify.com/show/3Pqrl9Xpuja6kSPjHUgxF4?si=0e673cd31d5d4217BIO:Taylor Welch is an investor & business consultant. His portfolio of companies have serviced over 50,000 individual small businesses in the last 5 years. He currently lives in Nashville Tennessee with his wife and 2 kidsCHAPTERS:00:00 Coming Up01:16 Warlocks and Witches01:57 Witchcraft vs Sorcery Basics02:13 Seeing Colors and Giftings07:05 Spells and Spiritual Tech09:40 Defining Witchcraft Today12:30 Placebo and Nocebo Explained17:36 African vs American Witchcraft19:37 Nocebo Stories and Extremes23:22 Casting Lots27:38 Christian Witches and Deception36:02 Genesis and Language Origins38:47 Nephesh and Human Authority41:53 Eden Contract Redefined43:20 Jesus Fulfills the Covenant44:39 Gospel as New Government45:47 Memorized Doctrine vs Relationship47:27 Agreements Give Darkness Access49:34 Spirit Realm Intention Matters52:14 Christian Witchcraft Exposed56:37 Why It Hides in Church01:00:04 Demons Riding Christians01:03:44 Spells Faith and Belief01:10:45 Infiltration Through Trusted Voices01:15:17 Leviathan vs Satan in Chaos01:18:56 Divination and Hidden Knowledge01:23:28 Omens and Soothsaying01:25:47 Mediums and Necromancy01:26:32 Source and Motives01:28:22 False Prophets and Fear01:32:47 Self Deception01:43:45 Perception Desire Action01:54:32 Words Without God's Heart01:58:50 Jacob to Israel Shift02:07:47 Worship Calms the Body02:12:35 Four Part Spiritual Audit02:20:28 Humility and Invitation

A sugar pill shouldn't work as well as a real drug ... except sometimes it does. In this episode, we explore the fascinating science of the placebo effect and how expectations can shape biological outcomes. From open-label placebos and AI healthcare chatbots to the nocebo effect, we unpack what scientists know, what they still don't understand, and why the placebo response is still largely mysterious. Check out Spirits here or wherever you listen to podcasts!A transcript and references for this episode can be found at acs.org/tinymatters.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

A Note from James:I'm doing a big experiment in my life.I recently started taking a GLP-1—tirzepatide, one of the so-called weight-loss drugs. But I didn't start taking it specifically for weight loss. I had some blood work done for the first time in a long time, and there was a small indication that I might be pre-diabetic. My doctor suggested trying tirzepatide, and I wanted to understand what I was getting into.The first person I wanted to talk to was Charles Duhigg, author of The Power of Habit and Supercommunicators. Charles has been taking a GLP-1 for about two years, and he says it has changed his life. He has lost around 45 pounds, but what interested me most was not just the weight loss. It was the habit change.Charles explains that GLP-1s can quiet what people now call “food noise”—the constant background pull toward eating even when you are not actually hungry. When that noise quiets down, something interesting happens: you get a window where your old habits become more malleable.That is the key idea of this conversation. The drug may help you eat less, but the bigger opportunity is that it gives you a chance to build new routines around food, exercise, alcohol, sleep, and identity. And if you build those habits while the window is open, those habits may continue even after you stop taking the medication.We talk about food noise, cravings, the habit loop, keystone habits, stated versus revealed preferences, placebo effects, alcohol, sleep, exercise, blood sugar, identity, and whether GLP-1s are a lifelong drug or a tool for changing who you become.Episode Description:James is at the beginning of a GLP-1 experiment. Charles Duhigg is two years in.In this conversation, Charles explains what he has learned from taking tirzepatide and from studying GLP-1s through the lens of habit formation. He describes the first phase of public understanding around these medications as weight loss. Phase two, he argues, is about behavior change.The central concept is “food noise.” Charles describes it as the background craving that turns a basket of fries into an almost automatic behavior. You may not even notice the noise until it goes away. Once it quiets, the cue that normally triggers the habit loop weakens. That creates a temporary window where new habits can be built.James and Charles use the GLP-1 experience to revisit the basic habit loop: cue, routine, reward. They talk about why habits feel automatic, why willpower is often the wrong tool, and why successful behavior change depends on identifying the cue and replacing the routine while still satisfying the underlying reward.Charles also introduces the idea of GLP-1s as a catalyst for keystone habits. Eating less can make exercise easier. Drinking less can improve sleep. Better sleep can improve focus. Focus can improve work. One changed habit can set off a chain reaction.The conversation then becomes more philosophical: Who are we if one part of the brain says “I want to be healthy,” while another part of the brain keeps revealing different preferences through action? Charles explains the difference between stated preferences and revealed preferences, and how repeated behavior can shift identity.This is not a conversation about taking GLP-1s casually. It is a conversation about using a medical intervention deliberately, under appropriate medical guidance, as a chance to change the patterns that shape daily life.Editorial Note:This episode discusses prescription medications, including tirzepatide and semaglutide, as well as personal experiences with GLP-1 drugs. It should not be treated as medical advice.GLP-1 medications can have side effects and risks, including gastrointestinal symptoms, dosing concerns, and contraindications for some patients. They should be used only under the supervision of a qualified medical professional. Any decision to start, stop, adjust, or combine medications should be made with a clinician.James and Charles also discuss personal experience, habit change, appetite, alcohol cravings, and identity. Individual responses to these medications vary.What You'll Learn:Why Charles believes GLP-1s are entering “phase two”: not just weight loss, but habit change.What “food noise” feels like—and why people often do not notice it until it disappears.How GLP-1s may create a temporary “habit window” where old routines become easier to change.Why the habit loop—cue, routine, reward—matters when trying to change eating behavior.Why people often regain weight after stopping GLP-1s if they have not built new habits.How keystone habits can create a chain reaction across food, exercise, alcohol, sleep, and focus.Why micro habits may work better than a full lifestyle overhaul.How stated preferences and revealed preferences shape identity.Why eating less can make exercise easier, and why exercise can reinforce healthier choices.Why tracking behavior may be essential while taking a GLP-1.How placebo, alter egos, and rituals may influence identity and performance.Why the goal is not just losing weight, but becoming the kind of person whose habits support health.Timestamped Chapters:[03:36] James Begins His GLP-1 ExperimentJames explains his early experience, including confusion between medication side effects and a bout of COVID.[04:16] Charles's Two-Year ExperienceCharles describes taking tirzepatide, losing roughly 45 pounds, and why the biggest changes came months into the process.[05:38] Phase One vs. Phase Two of GLP-1sPhase one was about appetite and weight loss. Phase two, Charles argues, is about habits that can last.[06:42] The Habit WindowHow GLP-1s can quiet food noise and create a period where eating habits become more malleable.[07:21] COVID, Side Effects, and Early SignalsJames explains why his first few weeks were hard to interpret and why he is still figuring out what the medication is doing.[09:00] What Food Noise Actually Feels LikeCharles uses the example of a basket of fries to explain cravings, cues, and automatic eating.[09:55] The Habit Loop: Cue, Routine, RewardCharles revisits the framework from The Power of Habit and applies it directly to food cravings.[10:42] How GLP-1s Interrupt the CueThe fries are still there, but the craving does not activate in the same way.[11:40] What GLP-1s Do in the Body and BrainCharles explains what researchers know about gastric emptying, glucagon-like peptides, and what remains uncertain about the brain.[12:43] What Happens When You StopWhy the medication alone may not be enough if old habits return after discontinuation.[13:36] Pleasure, Food, Alcohol, and AnhedoniaCharles discusses reduced pleasure from food and alcohol, while separating clinical findings from broader claims about losing joy in life.[15:54] Why Charles Stayed With ItEarly changes were not dramatic weight loss, but a growing feeling that eating became more of a choice.[16:40] Eating as a Keystone HabitHow changing food behavior can trigger changes in exercise, alcohol, sleep, focus, and work.[19:31] Why Structure MattersCharles explains why tracking and guided habit systems can help people see patterns they might miss on their own.[20:32] What Changes Physically Over TimeSlower stomach emptying, feeling full longer, more stable blood sugar, and gradual changes in appetite.[21:43] Stated Preferences vs. Revealed PreferencesWhy one part of the brain says “I want to change,” while another part watches what you actually do.[23:22] Identity Change and Habit FormationHow repeated behavior can teach the brain, “I am the kind of person who eats this way” or “I am the kind of person who exercises.”[24:16] Placebo, Belief, and Becoming the Person You Want to BeJames and Charles explore whether placebo effects may work partly by changing identity.[28:07] Alter Egos, Athletes, and RitualsThe conversation turns to Kobe Bryant, Michael Phelps, and how pre-performance routines can cue a desired identity.[29:15] Start With Micro HabitsCharles explains why small behavior changes can compound more effectively than trying to overhaul an entire life at once.[30:40] Charles's First Micro HabitsDrinking less, eating fewer fries, stopping when full, and choosing healthier meals without relying on willpower.[31:24] Feeling Full for the First TimeCharles describes the surprising experience of leaving food unfinished because his body had had enough.[33:03] Why the Stomach ShrinksThe medication does not shrink the stomach directly; eating less over time changes how much food the body expects.[33:21] Why Slower Stomach Emptying HelpsJames asks why a weight-loss drug would slow digestion instead of speeding metabolism.[35:00] The Cumulative EffectWhy the most visible changes often appear after several months, once habits, body size, and identity begin reinforcing each other.[37:03] Is a GLP-1 a Lifelong Drug?Charles explains what research and personal experience suggest about stopping, restarting, and maintaining results.[38:56] James's Health MotivationJames explains that his motivation is not primarily weight loss, but a desire to respond to possible pre-diabetic markers.[39:36] Why Attitude Is Not EnoughCharles argues that wanting to be healthy helps, but habit change still requires structure.[40:02] What Changed at HomeCharles explains how his family's food did not need to change, even though his own choices and portions did.[41:02] Weight, Body Composition, and Pre-DiabetesWhy blood sugar, insulin resistance, fat, and muscle matter more than the scale alone.[42:38] Semaglutide, Tirzepatide, and What Comes NextJames and Charles compare different GLP-1 medications and discuss how newer drugs may work through multiple receptors.[44:27] Will Charles Stop Taking It?Charles explains why he may eventually discontinue the medication, but values having more choice over weight and behavior.[45:24] Blood Work, Snoring, and Health MarkersCharles describes improvements in lab results, cholesterol, snoring, and overall health.[46:31] Who Are We, Really?James and Charles talk about identity, brain chemistry, sugar, alcohol, cravings, and the substances that shape behavior.[48:32] Choosing the Person You Want to BecomeCharles explains how better self-awareness can help people change habits deliberately rather than being pulled by cravings.[49:00] Tracking the ExperimentCharles advises James to track food, feelings, and behavior so he can notice changes that might otherwise be invisible.Additional Resources:Charles Duhigg Official WebsiteThe Power of Habit by Charles DuhiggSupercommunicators by Charles DuhiggNoom's GLP-1 Companion / Habit Formation AnnouncementFDA: Zepbound Approval for Chronic Weight ManagementFDA: Concerns With Unapproved GLP-1 Drugs Used for Weight LossBMJ: Weight Regain After Stopping Weight-Loss MedicationTodd Herman — The Alter Ego EffectSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

When filmmaker and homeopath Ananda More first encountered homeopathy, she dismissed it as pseudoscience. It wasn't until an unexpected experience while traveling through India that her certainty began to unravel. Years later—even after becoming a practicing homeopath herself—she still wrestled with the question: "is this all simply placebo?" That honest skepticism became the foundation for Magic Pills, a documentary exploring the science, stories, politics, and controversy surrounding one of the world's most debated healing modalities.In this conversation, we go far beyond the basics of homeopathy. We explore the difference between healthy skepticism and dogma, why homeopathy provokes such intense resistance, the state of the scientific research, censorship within medicine and media, energetic healing, placebo, consciousness, and what it means to follow evidence wherever it leads.Ananda also shares remarkable patient stories, discusses the global effort to preserve access to homeopathy, and explains why empowering parents with safe, non-toxic tools may be one of the most important investments we can make in future generations. Whether you're completely new to homeopathy or have questioned it for years, this conversation is an invitation to look deeper before deciding what to believe.Learn more about Ananda and her work:

Enquête historique et scientifique sur un mystère médical : l'effet placebo. Comment rien peut-il nous soigner ? Comment expliquer son efficacité prouvée par les neurosciences et connue depuis l'Antiquité ? Et si le placebo était une dimension essentielle du soin ?    Mettons en question l'effet placebo et toutes nos idées reçues sur le sujet dans un sens comme dans l'autre. Comment rien peut-il nous soigner ? Pourquoi tout est dans la tête, et c'est précisément pour cela que ça marche, mais jusqu'où et comment ? Qu'est-ce qui nous soigne le mieux au fond:  la substance active d'un médicament ? Le geste du soignant ? La relation de confiance ? Nos attentes ? Qu'est-ce qui se joue dans le placebo ? Et pourquoi est-ce une clé essentielle du soin, trop souvent disqualifiée et négligée par une médecine de plus en plus froide et technique ? Comment éviter à l'inverse les pièges et les douteuses promesses de guérison ? Mais aussi le terrible effet nocebo ? Avec - Richard Monvoisin, chercheur et enseignant en esprit critique à l'université Grenoble-Alpes, vulgarisateur reconnu, explore depuis vingt ans les frontières entre science, croyance et société.   - Léo Druart, chercheur à la prestigieuse Brown University aux États-Unis, apporte un regard neuroscientifique et international sur les effets contextuels du soin.  - Nicolas Pinsault, kinésithérapeute, professeur à l'université Grenoble- Alpes, allie la rigueur clinique à une réflexion sur l'éthique du soin.  Pour leur ouvrage, Placebo : enquête historique et scientifique sur un mystère médical paru aux Arènes.   Musiques diffusées dans l'émission Sage comme des sauvages - Lailakomo Angelique Kidjo - Malaïka.

Enquête historique et scientifique sur un mystère médical : l'effet placebo. Comment rien peut-il nous soigner ? Comment expliquer son efficacité prouvée par les neurosciences et connue depuis l'Antiquité ? Et si le placebo était une dimension essentielle du soin ?    Mettons en question l'effet placebo et toutes nos idées reçues sur le sujet dans un sens comme dans l'autre. Comment rien peut-il nous soigner ? Pourquoi tout est dans la tête, et c'est précisément pour cela que ça marche, mais jusqu'où et comment ? Qu'est-ce qui nous soigne le mieux au fond:  la substance active d'un médicament ? Le geste du soignant ? La relation de confiance ? Nos attentes ? Qu'est-ce qui se joue dans le placebo ? Et pourquoi est-ce une clé essentielle du soin, trop souvent disqualifiée et négligée par une médecine de plus en plus froide et technique ? Comment éviter à l'inverse les pièges et les douteuses promesses de guérison ? Mais aussi le terrible effet nocebo ? Avec - Richard Monvoisin, chercheur et enseignant en esprit critique à l'université Grenoble-Alpes, vulgarisateur reconnu, explore depuis vingt ans les frontières entre science, croyance et société.   - Léo Druart, chercheur à la prestigieuse Brown University aux États-Unis, apporte un regard neuroscientifique et international sur les effets contextuels du soin.  - Nicolas Pinsault, kinésithérapeute, professeur à l'université Grenoble- Alpes, allie la rigueur clinique à une réflexion sur l'éthique du soin.  Pour leur ouvrage, Placebo : enquête historique et scientifique sur un mystère médical paru aux Arènes.   Musiques diffusées dans l'émission Sage comme des sauvages - Lailakomo Angelique Kidjo - Malaïka.

Hello everyone. Welcome to the latest episode of The Matchbox Podcast powered by Ignition Coach Co. I'm your host, Adam Saban, and on this week's episode we're talking about our own anecdotes with the massive landscape of wearable devices.   As always, if you like what you hear, share this with your friends and leave us a five star review and if you have any questions for the show drop us an email at matchboxpod@gmail.com or head over to ignitioncoachco.com and fill out The Matchbox Podcast listener question form.    Alight let's get into it!   For more social media content, follow along @ignitioncoachco @adamsaban6 @dizzle_dillman @dylanjawnson @kait.maddox     https://patreon.com/MatchboxPodcast?utm_medium=unknown&utm_source=join_link&utm_campaign=creatorshare_creator&utm_content=copyLink   https://www.youtube.com/c/DylanJohnsonCycling https://www.ignitioncoachco.com        Summary: In this episode, we dive into the evolving world of wearable technology, assessing their real value for athletes and coaches. We explore which metrics matter, the effectiveness of blood work versus wearables, and practical tips for integrating data into training without over-relying on it.   Key Topics: The most useful wearable data fields for athletes and coaches Personal experiences with Whoop, Garmin, and other devices The potential placebo effect of wearables and how to interpret data critically The role of sleep tracking and hydration data in performance Blood tests vs. wearable metrics: what's more valuable? How to avoid over-analyzing wearable data and maintain intuitive training Encouragement to focus on body awareness and subjective feelings alongside tech The importance of baseline measurements like heart rate and power meters Using daily weigh-ins for hydration and weight management The limitations of current norms in blood work and health markers   Timestamps: 00:00 - Introduction and episode overview 00:30 - Common wearable devices discussed and used 01:13 - Wearables that measure beyond heart rate and power 01:53 - Wearables used during rides vs. daily devices 02:22 - Real-time data integration challenges 03:06 - Wearable usage for training impact versus outside activities 03:52 - The utility of Garmin and Whoop for sleep and HRV 04:55 - Using HRV and recovery scores to inform training decisions 06:09 - Research on HRV-guided training and its effectiveness 07:40 - Placebo effects and the psychological influence of wearable data 08:19 - Potential for subjective experience to outweigh wearable metrics 09:47 - The importance of sleep monitoring and behavior changes 12:38 - The psychological impact of wearable feedback on performance 14:36 - When and how coaches use wearable data for big-picture insights 16:15 - The value of blood work and biomarkers over time 27:22 - Advocating for regular blood testing and its potential with AI analysis 30:48 - The limitations of norms in blood work and health markers 31:45 - The benefits of daily weight tracking and hydration awareness 32:04 - Final thoughts on prioritizing blood tests over wearable spending

In this Huberman Lab Essentials episode, I explain the biology and psychology of obsessive-compulsive disorder (OCD) and describe the neural circuitry behind repetitive "thought-action loops," including why compulsive actions actually strengthen the underlying obsessions rather than relieve them. I discuss the most effective treatments for OCD, including exposure-based cognitive behavioral therapy and SSRIs, and explain what the research shows about how these compare when used alone versus together. Finally, I describe a specific clinical protocol in which patients are guided into states of anxiety while learning to suppress compulsive responses, retraining the brain to break the OCD cycle. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Eight Sleep: https://eightsleep.com/huberman Rorra: https://rorra.com/huberman Timestamps (00:00:00) Obsessive-Compulsive Disorder (OCD) (00:00:11) OCD Prevalence & Impact, Obsessions & Compulsions (00:01:54) Categories: Checking, Repetition & Order; Contamination & Disgust (00:04:30) Anxiety, Fear (00:05:20) Sponsor: AG1 (00:06:40) Genetic Component of OCD (00:08:45) Neural Circuitry, Cortex, Striatum, Thalamus (00:10:16) Cortico-Striatal-Thalamic Loop; Imaging Studies, SSRIs (00:14:30) Sponsor: Eight Sleep (00:16:00) Diagnosis, Yale-Brown Obsessive Compulsive Scale (Y-BOCS) (00:18:00) Y-BOCS Categories, Identifying the Core Fear (00:19:30) Tool: Cognitive Behavioral Therapy (CBT) & Exposure Therapy (00:21:39) Anxiety Tolerance, Interrupting the Compulsion (00:23:23) Dr. Helen Blair Simpson, Ritual Prevention, Exposure Sessions (00:25:18) CBT vs Placebo vs SSRIs (00:26:30) Sponsor: Rorra (00:28:07) SSRIs & Serotonin System; Psychiatry & Causality (00:29:13) Cannabis, CBD & OCD; Transcranial Magnetic Stimulation (TMS) (00:31:48) Mindfulness Meditation, Holistic Treatments, NIH (00:33:40) Nutraceuticals, Inositol; Recap & Conclusion Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

「安慰剂」在新药研发过程中处处可见，amylose 和 amylopectin是安慰剂糖丸的主要成分，其实就是淀粉（标题注释）。安慰剂效应究竟是应该被消除的统计噪声，还是一种被低估的真实治疗机制？当一针生理盐水能让帕金森患者的大脑释放出与真药相当的多巴胺，当假手术的疗效与真手术完全持平。我们要回答的问题是：如果安慰剂这么强，新药研发的投入还有意义吗？如果安慰剂能治病，我们可以只给病人吃糖丸吗？这期节目我们一起聊聊安慰剂效应在大脑中究竟通过哪些神经通路起效；它为什么越来越强以至于成为新药研发的障碍；我们可以只用安慰剂来治病吗？时间轴[00:14] 怀特先生的故事：一针盐水就让肿瘤消失了[02:54] 二战护士用生理盐水冒充吗啡止痛，战士不疼了[06:22] 不光吃药，手术也有安慰剂效应[12:32] 安慰剂不光能安慰，还能「反安慰」[19:10] 安慰剂管用的三条神经通路：内源性阿片系统、多巴胺奖赏系统、HPA 轴[28:32] 安慰剂成了新药上市的绊脚石[39:31] 临床试验如何对付安慰剂效应[44:14] 只用安慰剂能治病吗？

What happens when the doctor treating you is a cold, calculating AI trained on the deepest, darkest, most biased corners of the internet? This week, the boys sit down with Dr. Justin C. Key, a real-life psychiatrist and horror author who is literally writing the book on our medical doom. His new sci-fi thriller, The Hospital at the End of the World, explores the terrifying intersection of artificial intelligence and medicine. Justin joins us to unpack the big, messy questions: Is AI going to save a broken healthcare system, or is it just acting as a shiny digital band-aid for exhausted doctors who don't have the time to actually show up for their patients? We dive deep into the fascinating world of the placebo effect and why simply being seen and heard by a flawed, flesh-and-blood human is a crucial part of the healing process. Justin shares why he absolutely refuses to let AI write his clinical notes, arguing that the act of sitting down and thinking about the session is the real work. Follow Sickboy: Instagram: https://www.instagram.com/sickboypodcastTiktok: https://www.tiktok.com/@sickboypodcastDiscord: https://discord.gg/expeUDN

Jarrod Barakett has a unique perspective on health, healing, energy, and the future of wellness technology. In this conversation, he opens up about his journey from a major spinal surgery and being told to stay out of the gym for six months, to discovering The Light System and becoming one of the people leading the company forward.This episode is a deep conversation about wellness, frequency-based technology, light therapy, discipline, accountability, and the mind-body connection. Jarrod explains how he believes The Light System works, why he thinks the body already has the ability to heal itself, and how tools like full-spectrum light, affirmations, and electrical conductivity may support people in feeling and performing better.If you're interested in learning more about The Light System mentioned in this episode, you can check it out here:https://thelightsystems.shop/goetz100Use code GOETZ for access through the official affiliate link.In this episode, we discuss:- Jarrod's personal recovery story after emergency spinal surgery- How The Light System technology works- The role of full-spectrum light therapy, coded affirmations, and biophotonic collisions- Quantum charging, copper water bottles, and wearable wellness technology- The future of The Light System and its mission to help humanity healThis episode will resonate with people who are curious about alternative health, biohacking, energy, consciousness, wellness technology, personal discipline, and unconventional ideas that challenge mainstream health frameworks. If you enjoyed this conversation, subscribe for more long-form podcast episodes, leave a comment with your biggest takeaway, and share this episode with someone who likes thought-provoking conversations.0:00 Intro1:47 The Quantum Watch + Light System Technology4:15 Jared's First Experience With The Light System Cube9:56 Photons, Energy & Electrical Conductivity11:34 Jarrod's Spinal Surgery Story15:08 Choosing The Right Light System Linguistics17:03 How The Technology Was Invented18:17 How The Watch Works As A “Microdose”19:25 Why This Technology Is Still Unknown22:14 Science, Skepticism & What We Still Don't Know24:49 How Quantum Charging Works28:53 Electrical Conductivity Results30:18 Biocharger vs. Light System Technology31:42 Jarrod's Discipline After Surgery35:04 Why Growth Comes From Uncomfortable Moments39:35 How The Light System Helps Jarrod Operate Better41:21 What Healing Really Means42:59 Placebo, Belief & The Mind-Body Connection47:02 Purpose, Work Ethic & Family49:40 Other Healing Modalities Jarrod Uses53:08 Why Research Matters In Alternative Wellness54:41 What's Next For Jarrod Barakett And The Light System

What happens when the doctor treating you is a cold, calculating AI trained on the deepest, darkest, most biased corners of the internet? This week, the boys sit down with Dr. Justin C. Key, a real-life psychiatrist and horror author who is literally writing the book on our medical doom. His new sci-fi thriller, The Hospital at the End of the World, explores the terrifying intersection of artificial intelligence and medicine. Justin joins us to unpack the big, messy questions: Is AI going to save a broken healthcare system, or is it just acting as a shiny digital band-aid for exhausted doctors who don't have the time to actually show up for their patients? We dive deep into the fascinating world of the placebo effect and why simply being seen and heard by a flawed, flesh-and-blood human is a crucial part of the healing process. Justin shares why he absolutely refuses to let AI write his clinical notes, arguing that the act of sitting down and thinking about the session is the real work. Follow Sickboy: Instagram: https://www.instagram.com/sickboypodcastTiktok: https://www.tiktok.com/@sickboypodcastDiscord: https://discord.gg/expeUDN

Dr. Deb Muth 0:05What if your immune system isn’t broken, it’s just confused? What if chronic Lyme, the autoimmune condition, the food sensitivities, the exhaustion that never lifts what if those aren’t separate problems but one problem? A misfiring immune system that nobody taught how to stand down. Today’s guest has spent over 15 years doing exactly that, retraining the immune system from the inside out with a therapy so precise, so safe, and so effective that it has changed the lives of thousands of people who’d been written off by conventional medicine. Stay with me. This one changes everything.Welcome back to Let’s Talk Wellness Now, the show where we pull back the curtain on chronic illness, challenge outdated medical thinking, and hand you the real tools to heal from the inside out. I’m Dr. Deb, integrative and functional medicine practitioner, medical detective, and your straight-talking guide through the world of root cause medicine. Today, we’re going to dive deep into the immune system, specifically something called low-dose immunotherapy or LDI, and also into some hormones, chronic fatigue, and what it actually looks like to treat the cause instead of suppressing the symptoms. If you or someone you love has been told there’s nothing more we can do, this episode was made for you. Grab your cup of coffee, Settle in and let’s get to work. Now, before we bring in today’s guest, a quick word from our sponsor, and then we are diving straight in. I promise. Did you know sweating can literally heal your cells? Infrared saunas don’t just relax you, they detox your body, balance hormones, and boost mitochondrial energy. I’m obsessed with my HealthTech Sauna, and right now you can save $500 with my code at healthtechhealth.com/dr-muth-req-25.I want to start you with a story because this is one I’ve heard hundreds of times in my own practice, and I’m guessing you’ve either lived it or know someone who has. She’s 42. She’s been sick for years. Fatigue that doesn’t lift with sleep, joint pain that migrates, brain fog so thick she can’t finish a sentence, and a gut that seems to react to everything she eats. She’s been to her GP, rheumatologist, gastroenterologist, maybe even an immunologist, and every single lab comes back within quote unquote normal limits. She’s handed a prescription for something to manage the symptoms and sent home. Maybe she’s been told it’s anxiety. Maybe she’s been told it’s aging, or maybe and this one always breaks my heart she’s told it’s all in her head. That woman is not imagining it. She is not anxious and she’s not aging poorly. Her immune system has lost its ability to tolerate things it’s supposed to tolerate, and no one has offered her the therapy that could actually fix that. And what we’re talking about today with my guest has been practicing integrative medicine for over 15 years. Ty Vincent holds a medical degree from the University of Washington. He completed his family medicine residency in Anchorage, Alaska, and since has built one of the most impressive clinical repertoires I’ve seen anywhere in this field: acupuncture, Chinese medicine, environmental medicine, bioidentical hormones, hyperbaric medicine, chelation, regenerative peptide therapy, psychedelic-assisted therapy, and nutritional medicine.He lives and practices on the Big Island of Hawaii. He is married has 9 children. Oh my gosh, 9! And he has personally navigated type 1 diabetes, which, as you’ll hear, is not separate from his mission. It actually is his mission. And most importantly, he is a world authority on low-dose immunotherapy, a therapy he pioneered in 2008 and since has trained over 200 providers globally and changed the course of chronic illness care as we know it. I have had the pleasure of learning from Dr. Ty Vincent. I have had pleasure of taking his low-dose immunotherapy course when he first started back in like 2008 or 2009. I remember doing it back then and learning more about it in 2011. And this is going to be a great conversation for us. So one quick ask that I have for you guys, if this sounds like something that you want to learn more about and you’ve listened to some of our shows, please share like, subscribe. It means a lot. It helps us grow our channel. It helps us continue to provide for you different topics, different speakers, and really give you what it is that you’re looking for.So without further ado, I’d like to introduce you to Dr. Ty Vincent. All right, so Dr. Ty Vincent, this is gonna be a great conversation. We were just chatting before we went live of my training with you guys way back in like 2015, and I’m excited to hear all the new things that you’ve got going on. But introduce yourself to the audience. Tell us a little bit about you, how you got involved in this, uh, where you’re at, all that good stuff. Tyvincent 5:29Okay. I, uh, it’s a long story, but some of the highlights, I guess I was born in Alaska in the early ’70s and grew up there kind of wandering around in the woods with my dogs with no one around all day long. It was amazing. You don’t get kids don’t get that experience anymore. So you kind of learn to be an independent thinker, I think, you know, because latchkey kid, parents weren’t home till 6 and you’re on your own from early. Dr. Deb Muth 5:49That was a great time, wasn’t it? Yeah. Tyvincent 5:51I mean, I have, I have 9 children now and none of them grew up like me. And despite my effort, I mean, I’d have to basically like helicopter them out in the woods and drop them off for a few hours for them to understand what independent kids today are so dependent and parents are so helicopter that, uh, it’s changed. Anyway, I, I grew up just really liking science and really loving science, a huge nerd. And, um, and, uh, when I went into college, when I wanted to be a marine biologist and I thought that that was my passion of the ocean wildlife and all that, and then halfway through college, personal Couple things made me change my mind. It was a girl, you know, the usual. And I decided to go to school in Anchorage instead of going I was, I was transferring to Hawaii and I was going to study marine biology. And then, uh, my girlfriend moved back to Alaska where we were from. And I decided to do that instead. And then they didn’t have a marine science program.So I decided I’ll just get a biology degree and go to medical school. I’m a smart guy. I can do that, but I had no awareness of medicine. I really didn’t have any, you know, the passion some people have to be a healer and to go help people wasn’t part of the calculus at all for me. I was kind of an Asperger’s kid, so that really wasn’t the way I thought, honestly. And then I went into medicine and I was really interested in the science, the biology, the biochemistry, all the stuff, the physiology. And before I started medical school, I was reading some Andrew Weil’s books and I was, I decided to get a book on nutritional biochemistry because I naively thought that’s what they were going to teach me, right? This is how you make people healthy. You figure out how it works and you give them the things that make their body work right. Yeah. And we all know that that’s. Not been true for over 100 years now since the Flexner Report. And, you know, the rich people steered the government towards pharmaceuticals. Dr. Deb Muth 7:26Yeah. Tyvincent 7:26But that was my interest. And when I went through the first 2 years of medical school, I just really devoured all of the basic science stuff. And that was what I thought was the most important. And I honestly mastered all that. I scored in the top 1% in the country on all the exams and everything. And it was the top, in the top of my class at the University of Washington. And then you start doing clinical medical training and you discover that they don’t use any of that knowledge anymore, really, unless it pertains directly to pharmaceuticals, and that pharmaceutical research is extremely narrow and reductionist, and they only want to try to prove one little effect, and it doesn’t translate to real health. So as I got into clinical work and started residency, you know, by the third year of residency, I was like, they didn’t really teach me how to help people with chronic illness. You know, I was, I went to family medicine residency, so I was delivering babies.I was assisting with surgeries. I was in the ER. I was doing colonoscopies. I actually did colonoscopies in practice after residency, which family Doctors almost never get to do, but I’m a small town in Alaska. So I managed my own ICU patients and did everything, literally circumcisions in the office. And you’re dealing with like hospice and end of life care, just both ends, right? Pregnancy to death. And so I’d realized that if I really wanted to do the job well, which was my goal, I needed to learn other things. And in my, in my third year of residency, I actually did the extra, like, like additional training in medical acupuncture that was put on by the Helms Medical Institute then with Joseph Helms.And that was great. And I had to learn Chinese medical theory and I learned, I did the extra module on Chinese herbal medicine. And it was wonderful because I had to open my mind to a completely different way to evaluate people and illness. And I thought, okay, well then there’s got to be more. And as I went, I just became this voracious consumer of broad medical knowledge, not conventional medicine. You notice how a lot of the conventional people call it traditional medicine? Dr. Deb Muth 9:07Yes. Tyvincent 9:07Which annoys the crap out of me because there’s nothing traditional about something that’s been around for 100 years. I mean, you need time, you need like an epoch to say something’s traditional. But they’re like, no, I’m like, and then we were considered alternative medicine minded and everything like, oh, well, Well, it’s an alternative to real medicine. The vernacular in our culture really dictates thinking, unfortunately. I went on to learn functional medicine. So like 2005, I did the acupuncture training. 2006, I found the IFM and I read their entire textbook in a few months. And I went to the trainings. I was like, okay, now I know what you guys have to teach me. And then I found a bioidentical hormone therapy training course that was like Jonathan Wright and Terry Hertog. Dr. Deb Muth 9:46Terry Hertog, yes. My favorite guys. Tyvincent 9:49They were great. Dr. Deb Muth 9:50Pioneers, right? Tyvincent 9:51Yeah, exactly. And, you know, I learned what their opinions were and all that. And then you don’t really learn how to use a tool or you don’t get really get facile with something until you are using it and you’re applying it to your patients. And I went beyond that. I learned all kinds of IV nutrition. I learned chelation therapy. I joined the Environmental Medicine Academy and I learned how to do various forms of immunotherapy, eventually leading to learning LDA, low dose allergy therapy, through them in 2008. And for those of you listeners who don’t know about low-dose allergy therapy, when you learn about it, basically it’s like homeopathic dilutions of antigens.But instead of single antigens, like if you go to that regular allergist, they’ll just prick test you, blood test you, whatever, and say, oh, you react to mold, you react to chicken, you react to your husband’s whatever. They don’t test for that. I sometimes do. And they’re very narrow-minded about it. And it’s like you just give the antigens that the person tested for and you’re always missing something. With LDA, you get these huge broad mixtures of antigens, like for foods, it’s just hundreds of foods compiled into one for environmental allergens. And the reason you can get away with it is that the dilution factor is so far out. There’s no physical interaction with the body and you can’t, there’s no risk of inducing allergy, right? Whereas conventional shots might be 1,000 to 1, 100 to 1 dilution. We’re out at like a billion to 1 or further in most of these. And it sounded like nonsense to me, right? Despite all of my training I’d already had and all these things and being open-minded, it still sounded ridiculous. Pointless, right?But at least I was willing to give it a try because I had patients in my clinic, my family medicine clinic in Alaska, that had horrific allergies. Just like kids with eczema from head to toe. They look like they’ve been set on fire. Half their hair wouldn’t grow out of their head. They’re just miserable. They won’t grow. They’re on steroids. And I just thought, if there’s if this has any chance of working for these kids, I’m going to give it a try. Plus, two of my kids at the time had eczema, like persistent eczema that was really annoying. And I kids with eczema is a near and dear thing to me now. I like, I get emotional treating these kids, but, but that’s because it’s miserable for the families. Right. So I took it hard and I started treating my kids and, and, uh, kids in my clinic with LDA and it worked like magic because magic is just science we haven’t figured out yet. Right. We just, you know, some, but it was undeniable that it was working incredibly well. And then I was like, well, what is going on here? How does this work? And you learn the whole history of it. It goes back to the 1950s. I’m like, but, but it’s still so limited. There’s so much more as you start to treat patients with every tool in your toolbox, you run into these walls occasionally where you’re like, okay, everything I’m doing now isn’t working. And this patient has some kind of chronic inflammation, which is a very general term.People go, I have inflammation. Yeah, yeah. What we all do every day, all the time. But they would have these chronic inflammatory disorders that really seem to be immune driven. And then I thought, well, in terms of understanding low-dose allergy therapy, if I can identify what the target antigen really is that’s underlying this patient’s condition, and I can restore tolerance to that, which is basically how LDA works, then you could resolve it. And so I set about experimenting with all kinds of autoimmune disorders. I mean, at the time, LDA and the predecessor therapy called EPD, they had a few bacterial antigens, and we knew that there were connections between like rheumatoid arthritis and the bacterium Proteus. So that was in one. Klebsiella was the target antigen for ankylosing spondylitis. I’m thinking, well then, what about all these other autoimmune disorders? So I started just treating people creatively and trying all kinds of different things. Luckily, I had a contact in Orange County who had a warehouse, like a biomedical sample warehouse, and he was willing to give me antigen mixtures almost anything you could imagine in the biomedical world.The first thing I had him put together was Candida. I found those of us in the medicine space realize that some people have this huge problem with Candida. The conventional medical world thinks, well, yeah, everybody’s got Candida. That’s not a thing unless it’s an infection, blah, blah, blah. But you see these patients that are super ill, persistently ill, and you give them antifungals because you think, okay, well, you have these red rashes and itching and constipation and fatigue and muscle pain, blah, blah, whatever. It sounds like a yeast problem. Some of them, interestingly, if you do stool analysis, they show no yeast on their stool, which is a clue to me with a different thinking process that the reason the yeast isn’t growing in their stool is their immune system must be attacking it and killing it off in the gut, right? Because who doesn’t carry Candida? So the, the tests that run those are the stool company the test the companies that run the stool test, they don’t flag that result as abnormal because, yay, good, you have no yeast. But it’s horribly abnormal, right? Like if you saw somebody with no, no ears, you’re like, that’s not right. And so I thought, well, maybe they’re immunologically hypersensitive Candida. And so I, I was able to purchase a mixture of Candida species. And it occurred to me that I should include Saccharomyces cerevisiae in there because baker’s yeast and brewer’s yeast, people become sensitive to that too.So I made this and some of the patients that I was seeing where I would put them on Diflucan and Nystatin and all their symptoms would just evaporate, right? But you try to stop the medications after a month or whatever, and within 48 to 72 hours, their symptoms are right back. And that was one of the things, another clue to me, like, well, then that’s not an infection. I mean, they’re not taking antibiotics. They’re not eating a ton of sugar. Why would this regrow? And one of my criticisms of our integrative medicine world is we have just as many fairy tales and dogmatic beliefs as the conventional medical world. They’re just more colorful. Dr. Deb Muth 14:59That is true. That is very true. Yeah. Tyvincent 15:01And people were saying, oh, well, it’s because Candida lurks and hides in these nooks and crannies and corners in your body. And I’m like, I’ve done colonoscopies for years. I don’t know what you’re talking about. Like, it’s sparkling clean in there after some Go Lightly or whatever you torture your patient with the day before a colonoscopy. I was like, well, that doesn’t make sense. And they’re like, well, it’s because Candida uses mercury as a weapon to fight off your immune system. I’m like, you’re anthropomorphizing this organism as if it had agency to make tools, right? It doesn’t make sense. So then I came up with this idea to desensitize people to Candida. And it was incredibly effective.These patients, when you find the right dilution, you know, and for those who don’t know, it’s just a couple of drops of water put under your tongue, taken out of a syringe from multiple different dilution steps of the mixture, whether they’re using, right? So these people would respond. Most things I’ve developed, people respond. Somewhere near a trillion to one mathematically. And it was incredible. And I was like, okay, this is something that I’m sure relates to other chronic illness problems. And I started experimenting with I had a couple of patients with inflammatory bowel disease, ulcerative colitis, both of them early on. That was 2009. And I was like, well, they didn’t respond to the yeast mixture. They didn’t respond to the food mixture. And I was like, well, they’re reacting to something.And presumably that something is living in their gut. Right? I now know people react to different bacteria. There’s a ton of different bacteria and other organisms in your stool. So I came up with the crazy idea after seeing Dr. Bill Ray at an environmental medicine meeting talk about what he called autologous vaccines. Dr. Deb Muth 16:29Right? Tyvincent 16:30And I want to be clear, the way a vaccine works is probably the total opposite of how LDA works. It’s not the same thing. You’re restoring tolerance with LDA, LDI, and you’re promoting a robust immune reaction to a target antigen with a vaccine. At least that’s the theory. And now I’m not. It’s true. But Dr. Ray was talking about that and I thought, well, that’s a cool idea. And I went up and I asked him like, how do you do this?How do you make these things? And he kind of gave me like a very brief, you know, brush off. He didn’t know me very well. He’s like, oh, you get these Millipore filters, these little things you put on a syringe and you can dilute something and pass it through into a vial and it’ll be a sterile solution and you can dilute it. I was like, oh, great. So I collected one of my ulcerative colitis patients’ stool who was having at the time like 12 bloody bowel movements per day, every day. He’d seen all the conventional gastroenterologists. He tried the different drugs. They weren’t working. He went to some really special integrative greater clinic in California that primarily dealt with gastrointestinal disorders, and he did everything they wanted him to do, and it also didn’t help.I did discover that he was sensitive to gluten, and when he went off gluten, his, his gut still didn’t improve. So I made this autologous stool, um, LDA I called it then, which now I change it to LDI because LDA is a proprietary term and it’s also very narrow in scope. And I gave him doses and looked like the second dilution maybe that I went through hit. Literally his, his diarrhea and bleeding stopped overnight. And by 3 days he was having completely normal stools and no pain, nothing. And that taught me a couple of things. One, this theory works, right? And two, you know, we talk about the concept of leaky gut in the alternative medicine world, like integrative medicine world, sorry, a lot.And I’m like, yeah, but that’s not a diagnosis. That’s a symptom. You know, you still figure out what’s causing inflammation. And people are like, I just have leaky gut. It’s chronic. And you know, what do you do? And what I found was if you just put the fire out, the house rebuilds itself. Health very quickly. You know, we know that the lining of the gut turns over extremely fast. That’s why it is one of the first things to go when you do chemotherapy. And these people were basically healed to normal within less than a week. Same thing with kids with eczema that had these horrible oozing, weeping skin patches. Dr. Deb Muth 18:25I would. Tyvincent 18:25Or psoriasis even. When I developed some things that would treat psoriasis later on, you, you give this person with just, you know, deforming sort of rashes the right antigen, within 3 to 5 days they have normal looking skin except for maybe residual depigmentation or scarring if but it just blew me away. Dr. Deb Muth 18:42That’s crazy. 3 Days. Tyvincent 18:44The key to solving these problems was to restore immunological tolerance for the thing that it had lost tolerance for. Dr. Deb Muth 18:50Right. Tyvincent 18:50And it just really made me think about everything we were taught about chronic illness and everything we’re taught about the immune system in a very different way. And so since 2009, I’ve developed I’ve continued to develop new mixtures for new things because I run into patients. I can treat so many more things now highly successfully than I could before, but there’s still always the failures. People would ask me over the years, you know, why did you pick up all these skill sets?Like I learned acupuncture and Chinese medicine. I learned bio I became a Reiki master even, because I’m like, well, energy is a thing too. And so I get into the energy medicine world and that also works. And especially if you add it to acupuncture, it’s a great combination. All this stuff. And I would still fail. And I, it occurred to me when people ask me the question, like, I’m driven by failure. I really don’t like it. And I said, uh, and I thought that was how everybody believed, you know what everybody thought, right? But then you when you study our conventional medical colleagues and a lot of our people in the integrative medicine world too, that are doing the same things, the same protocols.And I hate the word protocol because it’s a poor substitute for thinking, right? It’s so that you don’t have to think here, follow this list, but everybody’s so different. So I never developed a protocol for anything to this day. I don’t, that’s not what I do. I was like, despite all of this, their patients aren’t getting better either. And it’s like, well then, you know, just philosophically, which I was a big philosophy student in college too. I thought if, if what you’re doing doesn’t work, do something different, you know, make new mistakes, figure things out. And I just got really creative. And by now I have, my gosh, I have 100 different kinds of antigen mixtures. And to be very honest, half of them have never worked for anything because that’s how it works, right? You got to. Dr. Deb Muth 20:17You’re trying it. Geez. Yeah. Tyvincent 20:19You’ve got to be willing to be wrong if you ever want to be right. One of the things I’ve noticed about humans in general is they’re very unwilling to see when they’re wrong because it’s emotionally painful to let go of something that has maybe been a part of your self-identity or especially like when you get experts in a field and they’re famous for some theory or treatment or whatever they developed, even if evidence shows up later, which it inevitably does, to show that what they’re doing isn’t complete, maybe not wrong, but not complete, there’s huge resistance, right, to the change. Dr. Deb Muth 20:49No one will admit that there’s something that didn’t work initially when they thought it did. Tyvincent 20:54Right. And nobody wants to admit I’ve been doing something wrong or ineffective or less than it could be for 20 years. You know, that’s unsettling. But to me, I’m like, well, isn’t it worse to keep doing it wrong? Right? Dr. Deb Muth 21:06That’s the whole idea. Like, right? We’re supposed to be bettering ourselves. Medicine’s supposed to be adapting and changing, and we don’t. Like, there’s a lot of things that we still do the same way we did in the 1950s and ’60s. Cancer treatment is one of them, right? We don’t really do anything different than we did back then. And when you look at precision medicine, we have all these new tools, but people stay stuck in their way of doing things just because maybe it’s easier, they’re comfortable or whatever. It doesn’t always make it the best interest for the client. Tyvincent 21:36No. And that is the goal we all need to keep in mind. Dr. Deb Muth 21:38Yeah. Tyvincent 21:39What I thought was like the job is to fix the problem the person has. And if the tools you currently have don’t do that, you need to learn something else. Dr. Deb Muth 21:48Yeah. Tyvincent 21:48And eventually I got a little saturated with learning new things. Dr. Deb Muth 21:51I’ve been there. Tyvincent 21:54Turns out there’s a limit. You know, we use the term drinking from the fire hose for everybody who like comes, like conventionally trained doctors who first get into the integrative medicine world. You’re just like, what are you talking about? It’s all so foreign and new. And then you have to use it and realize, okay, there’s, there’s a lot of truth here. But I got to a point where it’s like, I just don’t have the time in my day to use every tool. Like I bought an Indigo machine. I don’t know if you’ve heard of it. So the old EAV technology from Germany long ago, electrodiagnostic things and Then they developed computer programs and software that could analyze 11,000 different frequencies. It’s all energy frequency based. And I bought one of these for like $25,000. I still have it in the case collecting dust because I just didn’t have time to learn how to use the tool. And I was like, all right, I got to just get really, really good at some things and then let my colleagues who are good at other things help people with the things I can’t treat and I’ll tell them where to go. You know, it’s a collective, it’s a team effort. Dr. Deb Muth 22:47Right. It’s got to be a team effort. I’m curious what you’re finding these days with the newfound for mass cell, right? MCAS, everybody’s problem child, and nobody has a good answer. And it’s, it’s an immune reaction, right? It’s not just that I’m allergic to everything situation. Back in the day, 20 years ago, you and I would have called these the chemically sensitive people, and now we at least understand what’s going on. It’s an immune reaction. But I’m curious what you’re finding with LDI and that population of people. Tyvincent 23:19It’s a really good question. I know, I know you’ve had other interviews where people have discussed it philosophically to start the conversation. I really have found over the years that a diagnosis is the least helpful thing you can give your patient. Dr. Deb Muth 23:31Agreed. Tyvincent 23:31But we love labels. We love names. And we, and the problem is when you give something a name that does not reflect what’s actually going on, it just leads everybody’s brain in the wrong direction. And so there’s nothing wrong with these people’s mast cells. And that’s why I’m like, I despise the term mast cell activation disorder, but It is okay that they may be the end of the line releasing histamine and whatever, but a lot of these people have tons of inflammatory symptoms that have nothing to do with histamine, right? There are lots of mechanisms in the immune system that can give you cell-mediated inflammation or humoral, like antibody-mediated inflammation, different things. And mast cells are kind of an IgE thing, but it’s way more complicated than that.And when you work with these people, because a lot of them have found me because they have a very difficult time finding answers and solutions. I’ve been at most of us in this field have been at the bottom of a funnel where the options decrease because you try more and more therapies and they don’t work and the desperation increases kind of inversely proportionally. And then they’re trying weirder and weirder things that like people think are bizarre, you know, like you can eventually sting yourself with 20 bees a day, do apitherapy or something. Dr. Deb Muth 24:36I remember that therapy. And you know, as a practitioner too, it becomes more and more frustrating because it’s like, I’m trying all these things and nothing is working. What am I missing? And you keep trying different things until they just give up on you or you give up on them or whatever ends up happening, you know. Tyvincent 24:52Right. But again, like philosophically, every failure should lead you a step closer to success. Dr. Deb Muth 24:58Yeah. Tyvincent 24:58If you can look at it and you can learn from it what is possible from it and go, okay, I got to do this different or change this, or perhaps my entire theory about this problem is just dead wrong. Yeah. So if what I think is happening isn’t what’s happening, what else could be happening? And then you, you know, you come up with a theory and then you have to devise a way to test test it. And so like a lot of people probably tossed around theories about things being immune related or whatever over the years because it becomes a little obvious at a certain point, but they didn’t have a tool to test the theory.So that was the, the unique position I found myself in from 2009 onward was I’ve got a way to test this if I can figure out what antigen to try. And so I got a lot of mast cell people with that diagnosis. And, you know, my assessment of the problem is that when they come into my office, because like you and like most of people that are kind made it a little further in the integrative medicine world. The patients that find you have already seen 20 of your colleagues at the Mayo Clinic and the Cleveland Clinic and Germany, like Mexico, whatever. They’ve had exosomes infused up their nose or whatever. Like, all right, so what has not been explored yet? And you got to realize, okay, these, these people are there’s something going on. It’s very inflammatory. It’s probably immune related, but where is it coming from? Again, you mentioned root cause. You’ve got to trace the steps backward and try to figure out where is the point of intervention that will actually work and that’s feasible. And so what I found in these people, most of them have a pretty common early story of having had one or a few immune reactions that first began the process. And they might’ve been fairly benign and not that big of a deal.And then they go through some kind of immunological stress, whether it’s, well, some kind of stress, whether it’s a direct immune stress, like a vaccination or an infection or something like that. Like with COVID I’ve had an equal number of people who developed chronic immunological disorders after having the virus infection or having the vaccine. And the things that develop are virtually identical. So people are like, I should be gotten the vaccine. I’m like, it really doesn’t make any difference. Dr. Deb Muth 26:53Right. And I’ve seen the same thing with the HPV vaccine too. Like a lot of young people, they get that and all of a sudden their whole system is torn off after that. It’s very common. Tyvincent 27:03Except in that example, just getting HPV doesn’t do it. It’s the vaccine that does it. Dr. Deb Muth 27:07Vaccine that does it. Yes, exactly. Tyvincent 27:10Because everybody’s got HPV, you know, some other, and that is not in and of itself enough of an inflammatory trigger to lead to these chronic illness, right? You can lead to cancer, sure. Which is focal and it’s not a hypersensitivity problem. It’s a failure of immune defense problem. It’s a little different. So I would get these people and I’m like, okay, what happened first? What’s the beginning of the story? Because if you talk to them about how they’re feeling today, and a lot of your listeners, this will resonate with them. If I ask you how you’re doing today, the real cause of your problem is buried under a snowstorm of constant inflammation and your life experience is utter hell. And you have no clue what’s really triggering anything anymore. It’s like at a certain point, the immune system has developed PTSD, right? It’s just, it’s hypervigilant. Anything you give these people to take, even like vitamin C or whatever, then they go, ah, it made me worse.Ah, it made me worse. Because their immune system is now seeing anything foreign as an invader, as an enemy. So if you ask people just about how they’re doing today, you get absolutely nowhere. With these people. The one theory I had though was, well, maybe they’re reacting to histamine itself. Okay. I think is a beautiful theory. Makes total sense. Didn’t work at all. Spoiler alert. It’s not that it doesn’t work. It’s easy to get a sample of histamine, you know, and I also, I also got histidine, the amino acid from which it’s derived. I’ll say I’ll just put them together. So at least I want to say 12 years ago, I made like a histamine histidine LDI and everyone who had kind of the mast cell picture portfolio of illnesses, I would try it on. It has to this day, it’s never worked for anybody that I’ve tried it on. And I haven’t had another LDI practitioner tell me that it did. But again, that failure made me think about it in a different way. And so the success I’ve had with that population is not monolithic. It’s not one part. From an LDI perspective, figuring out what it is that they began to react to first, like, did you still have, do you have food problems originally?Oh yeah, I was kind of sensitive to gluten, but I just ate it anyway because I would just get some diarrhea and some, okay, it it was, it was livable, right? But they just keep exposing themselves to this trigger. And eventually something snaps in their immune system. Like they live in a moldy dorm room for 6 months and that all of that immune activation will kick off whole new immune response problems. And the world of mold is another area where I think people don’t, do not really understand what’s going on. And a lot of our treatment approaches don’t work for a large portion of these people. And it has to be kind of thought of in a broader sense. They could go through a divorce. They could have a car accident. They could have a surgery. A woman could have a baby, which is one of the biggest immunological triggers, unfortunately, is having a baby or early pregnancy miscarriage even is enough to do. Emotionally stressful. It’s physically stressful. It’s immunologically stressful.And then it swings your estrogen back up and you get this hypersensitive profile. But so all of these, what I call catalytic events were common in these people. And it’s not just one, it’s any one of them. And what I found was if I could identify what their initial triggers were categorically, right? Environmental things, chemical things, food. And if I could desensitize them to those, everything would settle down. And, and that was, that’s been the key to working with those people. But they want to tell you how horrible their life is today. Dr. Deb Muth 30:17Yeah. Tyvincent 30:17And you got to listen to that because you need the connection. You need to understand what they’re dealing with. You need to understand what their baseline is so that you can compare going forward. But the answers, the solutions aren’t in that story. And the solutions are in the history. And like, what’s the first thing you remember? And all this, like, okay, well, let’s go with foods. Let’s go with chemicals, whatever. And if somebody has distinctly worst triggers, right? Because right now they react kind of to everything. Any foods that you absolutely don’t eat because they give you the absolute worst reaction pattern, right? Oh yeah, I can’t eat these things. They’re the worst. Okay, well, maybe we’ll start with those and you can use those foods as your test exposures to determine if the dose works each time. So that’s one of the things I’ve developed stylistically over the years is the use of a test exposure if we’re using an allergen extract so that you can confirm or deny whether the therapy worked, right? Because people will tell you, oh, I feel better.Turns out that’s not worth much. You really need like, I mean, And belief is a huge part of that. Placebo effect is a huge part of that. You want to find something relatively objective, you know, so will you still vomit when you have chicken? You know, cause that’s like, that’s pretty obvious. And then go with that, you know, or do you still get a rash when you put on a bandaid? I love it when people get rashes from contact cause they can show me pictures and it’s not subjective, turns out. But even those reactions can go away 100% with placebo doses. It’s fascinating how people respond to placebos. So anyway, I try to find like the root beginning allergens. And then a lot of these people also accumulate other target antigens as they go through their process of being ill. Their immune system is so upset and it’s, it’s also just blurry vision, right? It attacks anything. Angry dog on a chain. If you get close enough, it’ll bite you. It doesn’t care who you are. And that’s how their immune systems get.So finding the antigens that are root cause is key. But a lot of these people have developed over time total adrenal burnout. Out, right? Because they’re in state of chronic inflammation, everything. So I also found that I had to lean on my skill in bioidentical hormone therapy, which over all the years I’ve been in integrative medicine, the two major skill areas that gave me the best results in general were hormonal management and immunological modulation. I got so many of the prior failures I was able to solve with those two things. And so if I would support these people’s adrenal, like hormones, you know, DHEA, cortisol, to optimal levels, a lot of them, their symptoms would cut by half, number one. And you would have a little more clarity as to what their actual triggers were.So in a lot of these cases, I learned to start with that before I even decided what antigens to pick. You can kind of get the snowstorm to calm down. You can start to find the snowmen in the blizzard that you couldn’t see before with all the chaos. I was like, okay, now that you’re feeling better most of the time, you can tell that these chemicals bother you, that mold exposure bothers you, that whatever, and then you can target things But the other third kind of leg of the tripod that I found are the keys to success with our most complex patients is to address like the hormonal issue, the immunological issue, but the subconscious fear response, the subconscious stress response in them. Dr. Deb Muth 33:14Trauma. Tyvincent 33:15And I saw that you’ve also people, yeah, trauma and people have medical trauma, not just trauma from their illness itself, but trauma from seeing 12 doctors that treated them like they were a head case and ignored what’s going on. Dr. Deb Muth 33:25Of the medical community, right? Tyvincent 33:27Oh God, you know, like people— yeah, the more doctors you see, the more your trust in doctors goes down. Dr. Deb Muth 33:34Yes, exactly. Tyvincent 33:35They see one of us and some of them just automatically are like, whatever, here’s another failure coming my way, kind of thing, you know, realistic. Partly because it becomes too risky to have hope, right? Like after a while you’ve had hope, hope, and it’s been dashed, and you just can only handle that so many times. It’s like you fall in love and then they dump W. And after a while you’re like, I’m celibate. I don’t care anymore. Um, so you get these people and what we have found, my wife and I started doing psychedelic-assisted therapy with patients a few years back. In fact, this little cottage on my property we built specifically for that purpose. People can come and stay here for a couple of days.There’s a bedroom on the other side of this wall. And we do therapy with them. We have a very good process of getting their hormones tested before they come, trying to correct any deficiencies or imbalances, especially cortisol and DHEA. We try to make sure that if they have immune problems that seem manageable, we maybe try to control those first. But in a lot of these people, we have to get their subconscious fire alarm to go off first because anything new that enters into their sphere of existence is seen as this, you know, scary thing. Dr. Deb Muth 34:36Yeah. Tyvincent 34:36And so what we found is getting their subconscious to settle down, getting them to integrate past whatever trauma they’ve had so that it’s no longer causing harm today from an experience 20 years ago, right? Because that’s not fair. A lot of these people, all of their immune stuff stops and I don’t even have to do LDI. And that’s fascinating. And some of them, we put them on hormone replacement, everything calms down enough. It’s like one of these things sometimes works. And in other people, they need all three. And the trick in those people is to figure out what thread you have to pull on first. You know, it’s like, well, okay. And we spend a lot of time, my wife and I both work with patients together. She’s amazing. She’s not a trained clinical clinician. You know, she had a business degree, but she’s like, she tells people I attended the school of Dr. Ty Vincent for 10 years. Dr. Deb Muth 35:20Yes. Tyvincent 35:21Heard him say all this a million times. And when we first started seeing patients from home together, she read all of my patient notes and just great. So she. Dr. Deb Muth 35:28Yeah, that’s how you learn. Tyvincent 35:30Yeah. And people like, well, I didn’t go she’s like, I didn’t go to medical school. I’m like, that’s an asset, trust me. Dr. Deb Muth (35:34-35:40)Exactly. Oh my God, you haven’t been brainwashed. Exactly. Tyvincent 35:40And you know, it’s not even so much washing as it is like throwing mud all over the walls. All of these false beliefs you’re given, and, you know, not just the beliefs, but the disbeliefs, both of those hold people back. And I was like, it’s your disbeliefs that are the bigger problem because you don’t even realize they’re there. Like when I learned about LDA, I’m like, that’s nonsense. No, it’s not. Dr. Deb Muth 36:02I’m curious, when you treat some of these complex people with LDI, are you using multiple modalities at one time, or are you being really cautious with them and using one at a time? Time, because some of them won’t let you do more than one thing at a time with them. Tyvincent 36:16And so by modalities, you mean like, are we also doing hormone therapy? Are they also doing like IV, like other things? Or you mean multiple antigens within? Dr. Deb Muth 36:24Multiple antigens, yeah. Tyvincent 36:25Um, it really depends. And early on, so I everything I know about LDI, I learned through experience, paying attention, putting connecting dots over you. And it’s been been a very long process, right? Early on, like a kid in a candy store, you see a patient and you find out, oh, they’re allergic to some foods, they’re allergic to some chemicals, they’re allergic to cats and birch tree pollen, and they also have psoriasis or whatever. And you’re like, ooh, I’m going to give you all 4 of these antigen mixtures because you have all 4 of these issues. And by 6 months in, if you’re paying attention, you are completely confused and lost. Dr. Deb Muth 37:03Yeah. Tyvincent 37:04I did that for a number of years and I thought, well, this will be the fastest way to figure things out. It turns out it’s not, unfortunately. Um, what I’ve found is more successful is if I can figure out either what the most important underlying immune reaction is for them that might be cascading into other problems, or you figure out what’s the easiest one to solve first. So if somebody has like the whole mast cell picture and they got all this stuff going on, but they say the biggest thing is I have horrible chemical reactions. I’m a tr I’m trapped in my home. I created an oasis of safety here, but I can’t go anywhere. Anyone who comes to my house has to go into the entryway and take all their clothes off and put on a jumpsuit, right? There are those people. I work with them. Dr. Deb Muth 37:40Oh yeah, I have those clients. Tyvincent 37:42They’re like, oh my God. Well, if we can fix that first, your world will open up a ton. Your fear will come down. Your immune response will come down. And so sometimes it’s a matter of which one seems the most important or which one seems easiest. Like, okay, the test exposures that they have are the most obvious and distinct. For foods and not chemicals or whatever. And the reactions people have to these different antigens can overlap tremendously or even look exactly the same, which is why you kind of need to use one at a time. Because if you’re trying to ride a bike and a motorcycle at the same time, it doesn’t go so well. Dr. Deb Muth 38:16Yeah. Tyvincent 38:16Like, let’s find where you do with where you respond to this one, and then we will have less stuff to deal with. We might have a little bit more clarity as to what you’re reacting to in other categories. And then you kind of go through them sequentially. But if I have somebody who’s not like just in a real state of immunological distress like that, and they go, yeah, I’m allergic to cats and I have a cat because I’ll never get rid of my cat. I don’t understand those people, but, but there are a lot of them. They love their cats. Dr. Deb Muth 38:43A lot of them. Yes. Tyvincent 38:44I’m like, okay, or dog, you know, I’ve had people that are horribly allergic to dogs and the dog still sleeps in bed with them every night. Dr. Deb Muth 38:50Okay. Tyvincent 38:51Um, they’ve got that, that’s very clear, very distinct. And it’s, and it’s like a rash or a runny nose. And then they also have have celiac disease, let’s say. Like, well, we can treat both of those at the same time because the symptoms are totally different. You have test exposures in both categories and you’re not so sick that you’re in a constant state of like trauma response where you can’t even pay attention to anything. Right. And so it’s kind of case by case. And my style is very, very individualized. Like I said, there’s never a protocol. It’s like, I got to talk to people for about I usually talk to people for about an hour. Yeah. More than isn’t really helpful. You know, like, in an hour of time, you’re, you’re kind of saturated with how much you can invest your bandwidth into this particular issue. Now, like, okay, I know where we’re going to start. I don’t know where we’re going to end up, but I know where we’re going to start. And so we encapsulate that and then go, let’s do this. And then everything you do teaches you more about what else you need to do.And it’s a process. I my ego used to be more tied to guessing correctly at the beginning about what was going to work work and to fixing things quickly. And over time I realized like your ego really has no place in the exam room. Like that is a very, very challenging thing for practitioners to try to figure out is how to get your ego out of this because it biases you intellectually, emotionally, and it’s a problem. And our medical colleagues probably have bigger egos than the average human in the population. Let’s be honest. Um, there’s something that comes with the years of study and the investment and the status you have, and it’s a challenge. But if you be like, I just need to be clear about what’s happening, what’s not happening, and you figure things out. And so I was able to have a much better success rate approaching things that way.And every time you put out one little fire for people, one kind of immune response, it, you, you get a better picture about what else is going on. And then eventually all their problems have stopped and you’re okay, cool. I guess we’re done. But it’s, it’s hard. And you do learn that there are still major gaps in your knowledge. And, and you asked earlier about new developments in LDI. And whatnot. And I could literally talk all day about the things that I’ve developed over the years, but I still keep making new antigens. So just last year in the area of food allergy, so like your Mast Cell people, a lot of them have food allergies that are a big part of the underlying problem, and this will be relevant to them. But what I found is a lot of the people who seem to clearly react to food, and I put food in quotes because most of what Americans eat isn’t food, right? It’s it’s at least it’s not just food, or it used to be food and now it’s not. It’s like Frankenfood, and it’s got chemicals in it. It has molecules that don’t exist in nature, so you can react to them.So I found some of these people that would say, oh, I react to processed food items horribly, but if I eat the whole foods, organic whole foods at home, I don’t react. And, um, some of those people will resolve those problems with the chemical LD mixture. So they’re reacting to chem with that. A lot of them will tell you, oh, I also react to perfume. Or gasoline or whatever. Dr. Deb Muth 41:46Yeah. Tyvincent 41:46Okay. And so you can use that and some of those cases will resolve, but a lot of them don’t. And I had increasing failures. Like I’ve been doing this long enough to see and observe that early on I had much better success with these antigen mixtures than over time. People are the pattern and the causes and the manifestations of illness today are evolving right before our eyes because of what we’ve done to our environment and our food and ourselves. So what I came to to sort of theorize about was that maybe some of these people are reacting to processed cooking oils, like seed oils, plant oils that are put into processed foods, right? Because they would tell me a couple of key cases gave me that insight. They would say, well, I still react to all these processed foods.I can’t eat at restaurants, and I’m still reacting horribly to sesame seeds, or I’m still reacting horribly to flax, or I’m still reacting horribly to, like, one of these other things we make processed seed oils from. Well, maybe they’re reacting to the oils. And when we made the food mixture, you use whole food samples, right? So you use like a, a ses like sesame seeds, or I use tahini paste because it’s easier to mix in water. But maybe the antigen, the target antigen, is something inside that that is not properly like, what’s the word I’m looking for properly given to the immune system, or, or like exposed, shown to the immune system, right, in the way that their immune system is reacting to it. Maybe it’s a molecule in there that when you use a whole food antigen is not adequately represented. It’s like, so an oil would do that.And I had actually already years ago realized that some people react to essential oils, like flower extracts or tea tree oil or lavender or whatever. Right. And so I made an essential oils mixture from plant oils from the doTERRA and the Young Living products. I had a couple of patients that were like distributors for these things. And I said, just take an empty vial and put one drop of every single product you have in it and just mail it to me. And they both did that. So I have this huge compendium of essential oils, and I would get people that would still react to oranges and lemons and citrus fruits despite the food mixture. And then the essential oils mixture would totally stop that reaction. So I’d already kind of proven that this was the case with some of those more aromatic oils, right? Now I was like, well, people are reacting to the processed cooking oils because when you take oils out of the plant, if you ever do this at home, they’re opaque and gooey and viscous. And then somehow it’s this really pretty homogeneous, clear liquid that doesn’t separate at all. It has no nothing you see in there.And then you got to wonder, how the hell did they do that? What did they do to make that? And there are all these chemical processes and heat and everything. I’m like, well, it just makes new molecules that your immune system has never seen before. So in May of 2025, I bought 18 different kinds of plant oils, and some of them are really pure, like carrot seed oil, cottonseed oil. But there’s peanut oil and avocado oil and olive oil and, you know, all the seeds and things we use in there. And I even have a video on our Facebook page and probably Instagram of me making this mixture in my kitchen.I was like, people are kind of interested how this works. And I just made it right there on camera because it’s really simple. I started using it in some of my failure cases that had really seemed like they had food allergy responses, but the food mixture didn’t work. And the first one was actually one of our employees who does our social media management. She had a 3-year-old son, I think, probably 2 years old when we started working with him, with really bad body-wide eczema, right? And he never really responded to the food mixture, essential oils, skin bacteria, skin fungi, yeast. I tried all the things that usually work. I’m like, it’s something. And so he made the oil mixture. He was they were the first one. I just sent the doses like, hey, let’s check it out. And I think he got for I started 6C for most things, which is a truly and then it’s like 5.5C, 5C. We got to 3.5C, I think, is where he is, which is a dilution of of 10 million to 1, I believe. And 95% of his eczema just completely went away. Dr. Deb Muth 45:38Wow. Tyvincent 45:39The only thing left was a couple of those patches on his feet. And one of the things I learned about people with eczema is they will have localized, like geographically local consistent reactions to different things. This is crazy, right? Dr. Deb Muth 45:53Yeah. Tyvincent 45:53Your immune system has kind of a, you know, like an overall regulatory system, but it also has regionalized systems, just like the government federal government, state government, county government, city government. It’s, it’s divided like that. So the people will eventually learn, oh, if I eat gluten, I get these itchy bumps on the side of my hand, and if I eat carrots, I get a rash on top of my head, you know. And it’s very, very clear once you identify it. So there’s still something that kid’s reacting to that I haven’t quite solved on his feet. But, um, yeah, that worked amazingly, and it actually made me cry when I got the pictures She’s like, oh, finally, after probably a year and a half of flailing, you know, we got it right. And so now I’ve been using the cooking oils mixture more and more and more. Just yesterday I got an email. I have a teenager, he’s 8, he’s maybe 18, 17, 18, with just really horrible cystic acne, painful, erupting. And the before pictures are just hard to look. I mean, he’s got horrible involvement of both sides of the face, the chest, all over his back, and you can just see the scarring and the redness and the inflammation.And we went through the food mixture with him and whatnot, and it really didn’t touch it. So yesterday I got the report. He got up to the cooking oil mixture at 2.5C, which is 10,000, 100,000 to 1, and, and his cystic acne stopped. Like, he’s getting zero new lesions. All the redness, pain, inflammation is gone, but he still has all this just scarring from it because that’s permanent, right? You have to get that repurposed. And all he has left is little tiny whitehead pimples, like maybe one new one per day here and there. You can see them now in the midst of all this. So acne is diversified. There are different kinds of acne and people can have more than one type and they can react to hormones. They can react like I’ve had guys with bad acne respond to desensitization with testosterone, for example, or women desensitizing them to estrogen or progesterone and the acne will go away sometimes. Some people respond to yeast, some people respond to skin bacteria, skin fungi. And so this is another thing. And my wife actually is one of the more complicated immunological cases I’ve ever had to work with. Working together for 10 years, um, you know, like the first time I saw her, she had Lyme disease and the Lyme LDI just totally stopped those symptoms like magic, which is great.That’s one of my favorite things to treat. Um, because the beliefs we have about Lyme disease, I have found completely untrue because using a different tool. I’m like, oh, it’s an immune problem, not an infection. So anyway, so that, that worked for her. Some of her food reactions went away, but she still continued to get like deep painful cysts if she would have nuts or dairy. And so the cooking oil mixture now, after 10 years of being together, totally stopped those reactions. Peanuts, nuts, dairy. And the dairy one is interesting to me because it’s not a plant oil, right? It’s an animal oil and it’s not represented. And we have dairy products in our other mixture. But I think what’s happening is when cows are fed grain, sometimes what an animal is eating carries through some essence or nature of that substance into the milk. Um, and the thing I’ve seen this the most clearly with is corn. Corn allergy is a very unique situation. The way people deal with it, the way it manifests, the way you have to treat it is different from every other energy. And I don’t have an hour to talk about that specifically, but I observed primarily with corn that anywhere along the food chain, you’ll still react to that food if the animal at the beginning was ever fed corn. Multiple I’ll have babies that get an eczema reaction or a GI reaction if mom eats corn-fed beef. But if mom eats grass-fed beef and then nurses the baby, they’re fine. Dr. Deb Muth 49:33Yeah, I’ve seen that too. Tyvincent 49:34It’s bizarre. Dr. Deb Muth 49:35Yeah. Tied. This has been really so amazing. Um, tell us how people can find you if, if this is resonating with them and they’re like, I need him to figure out the puzzle for me. How do they find you? Tyvincent 49:49So the best thing to do is to go to our website. Our, our business name is Global Immunotherapy, and the website is just http://www.globalimmunotherapy.com. We have, we have a much better website than we did years ago. People schedule directly through the website. Right? There’s all kinds of information. I’ve been making YouTube videos and informational videos for people for more than a decade now because nobody has any idea what I’m talking about. The more they understand it beforehand, one, they get to decide if they just think I’m crazy, right? And they don’t want to waste their time. And there are plenty of those people, but a lot end up talking to me 3 years later because after they’ve tried everybody else and there’s nothing left to try, right? Yeah, yeah, like being at the bottom of the desperation funnel. Yeah, people like, well, I heard about you 5 years ago and didn’t make sense. I’m like, yeah, cool. But then I had 3 or 4 other people over the years tell me I should talk to you. So here I am. That’s, that’s right. And people can watch all these educational instructional videos about how LDI works, what it can be used for. So the more you learn and understand what you’re getting into ahead of time, the less time we have to spend during our hour trying to explain to you the therapy., which to take up half the time and better results you’re going to get because you’re educated and it’s a partnership.Like all of us in the world of integrative medicine, one of the big differences between us and conventional medicine is we understand that it’s a partnership. You have to listen to the patient, you have to educate the patient, you have to engage them in their own health. You can’t just say, here, take this pill and come back in 3 months and I’ll check your labs again to see that you still have the same illness. It’s just and people have a lot of our population has been led to believe that just swallowing a pill is going to fix your problems. But That doesn’t work. And we have to develop a relationship and an understanding and shared knowledge and beliefs. And so people now, they have this opportunity to watch all the videos. And I really want people to do that before they ever schedule, because one, you’ll, you’ll feel like it’s the right therapy for you. And that helps a lot. Having optimism going in is super helpful. And then two, you already know a lot. So you’ll know more about what questions I might ask you and how to answer them. You’ll know more about about how the therapy works, and I won’t have to explain it to you, and we’ll get a better use of our time. And then people can schedule right through the website with either myself or my wife Jeanette. And anybody who Jeanette talks to, she reviews every case with me, and we work together with stuff. And, but in terms of like using LDI, she’s probably the second or third best practitioner in the world. I

Brian Molko joins Alan for a brilliantly funny flight, from an unforgettable airport encounter with Alan that reminds Brian of David Bowie, to why he finally decided to revisit Placebo's debut album 30 years later. They talk about rebuilding his relationship with those early songs ahead of Placebo's 30th anniversary tour and the band's debut album, newly RE:CREATED, why the Britpop era made Placebo stand out, and reclaiming Nancy Boy. Along the way there's talk of memory tricks, cannibals, Magaluf, airports, sharks in the Maldives, rehab romances, why Brian believes arriving is the best part of travelling, and an unforgettable quick-fire round. Plus, Brian reveals why this anniversary tour he's been able to celebrate Placebo's earliest music with genuine joy. 00:00 Brian's fear of flying and the luxury of Alanair01:08 The Alan airport encounter that reminded Brian of David Bowie08:00 Why Brian recreated Placebo's debut album09:57 Standing apart from Britpop and embracing difference12:11 Rediscovering the debut album after 25 years12:51 The story behind Nancy Boy14:06 Memory, the Mandela Effect and false memories15:13 Alan pitches “Pla-subo" featuring Susan Boyle16:03 Placenta parties, cannibalism and "long pigs"17:18 Forgetfulness, daydreaming and useless knowledge18:13 Loving the destination but hating the journey20:26 Smoking on planes and Brian's airport theories21:53 Placebo's 30th anniversary tour and finding joy again24:14 Brian's holiday nightmare in Magaluf26:06 Rehab romances27:32 Why kindness gets better service than complaining30:02 The Maldives, rabbits and reef sharks32:04 Eating street food in Bangkok33:16 Quick Fire: beach or pool, window or aisle?35:38 Alan's stage fright wee and Brian's bladder training tips37:40 Why everyone should tip their delivery driver #LifesABeach #AlanCarr #BrianMolko #Placebo #Placebo30 #AlternativeRock #RockMusic #DavidBowie #Britpop #NancyBoy #Travel #AnniversaryTour Learn more about your ad choices. Visit megaphone.fm/adchoices

Episode 3 - You're not a machine. Placebo, epigenetic's and Inna Segal's own healing reveal how the mind shapes the body - and what your symptoms are trying to say.Disclaimer: Please note that all information and content on the UK Health Radio Network, all its radio broadcasts and podcasts are provided by the authors, producers, presenters and companies themselves and is only intended as additional information to your general knowledge. As a service to our listeners/readers our programs/content are for general information and entertainment only.  The UK Health Radio Network does not recommend, endorse, or object to the views, products or topics expressed or discussed by show hosts or their guests, authors and interviewees.  We suggest you always consult with your own professional – personal, medical, financial or legal advisor. So please do not delay or disregard any professional – personal, medical, financial or legal advice received due to something you have heard or read on the UK Health Radio Network.

This week Terry and Paul were just wanting some free universal health care when they meet Dr. Leslie Coburn, who has a history of treating one of her reoccuring hypochondriac patients with various placebos to great effect. However, this time, his symptoms appear real and they quickly spreading to those around him...

What happens inside your brain when you're pushing your limits?In this episode, we sit down with Professor David Spindler to explore the science behind better performance. From making decisions under fatigue to managing emotions during hard efforts, we discuss how your brain influences the way you train, race, and recover.David explains why breathing is one of the simplest and most effective tools for regulating your nervous system, how your brain responds when you're under physical stress, and what athletes can do to make better decisions when the pressure is on. We also dive into pacing strategies, mental resilience, and how a better understanding of the brain can help you perform more consistently, both in sport and everyday life.Whether you're preparing for your next race or simply looking to train smarter, this conversation is full of practical insights that will change the way you think about performance.Key Topics• How the nervous system influences performance• Making better decisions under fatigue• Breathing and self-regulation during training and racing• The role of brain chemistry in endurance performance• Pacing strategies for long-duration efforts• Building mental resilience through neuroscience

Brice Conrad - Oh la Serge Gainsbourg - Sorry Angel Lancelot - Un homme seul Helena - Tout a changé (Rien n'a changé) M - Onde sensuelle Zaoui & Stéphane - Love Noir Kyo - Ultraviolent Vivien Savage - La petite lady Louane - Conduire Stephan Eicher - Pas d'ami (comme toi) Hoshi - Ta marinière Indochine - No Name Kaolin - Partons vite Amir - J'ai cherché Art Mengo - Les parfums de sa vie (je l'ai tant aimé) Clara Luciani - La Grenade Tryo - L'hymne de nos campagnes Vanessa Paradis - Rendez-vous Charlotte Cardin - Tant pis pour elle Tarmac - Notre époque Zazie - Peu importe Pierre de Maere - Je pense à vous Téléphone - Ça c'est vraiment toi Jeanne Bonjour - Finir par en rire Les Innocents - Un homme extraordinaire Vianney - Moi aimer toi Gérald De Palmas - Tomber Calogero - Avant toi David Hallyday - Tu ne m'as pas laissé le temps Alliel - Encore Placebo - Protège-moi Hébergé par Audiomeans. Visitez audiomeans.fr/politique-de-confidentialite pour plus d'informations.

Captain Alan welcomes on board Placebo's Brian Molko! They talk first meetings, tour buses, the Maldives and Magaluf. Be prepared for the chat to take some surprisingly dark turns. And of course Brian's celebrating their new album Placebo RE:CREATED, a totally reworked version of their debut album, and their embark on 30th anniversary European and UK tour, which starts in September. A 'Keep It Light Media' Production Sales, advertising, and general enquiries: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠hello@keepitlightmedia.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices

Send us Fan Mail✈️⚖️ Der Tarifkonflikt zwischen Lufthansa und der Pilotengewerkschaft Vereinigung Cockpit geht in die nächste Runde. Nach dem Pilotenstreik im März 2026 hat Lufthansa eine Vereinbarung über bezahlte Freistellungen gekündigt – jetzt zieht die Gewerkschaft vor das Arbeitsgericht Köln. Was steckt hinter dem Streit, welche Argumente bringen beide Seiten vor und welche Folgen könnte das für die Lufthansa-Piloten haben? Alle Hintergründe in diesem Video.

Bun venit la o nouă ediție Vorbitorincii! Astăzi avem un episod plin de povești din călătorii, analize ale realității românești, recomandări culturale de top și un invitat special alături de care pătrundem în cele mai ascunse culise ale investigațiilor jurnalistice. Nu uitați să vă abonați, să dați un like și să ne lăsați părerile voastre în comentarii! ANUNȚ IMPORTANT | VORBITORINCII LA TIMIȘOARA: Sâmbătă, pe 27 iunie, venim la Timișoara împreună cu Cosmin Popa! Mai sunt doar câteva bilete disponibile. Găsiți linkul pentru bilete în comentarii. 00:01:35 - De la Madrid în Țara Bascilor vs. atmosfera de la TIFF. Despre dezamăgiri politice și comunități care inspiră. Radu povestește despre lansarea romanului „Fluturele negru" în spaniolă și vacanța spectaculoasă prin Bilbao, San Sebastian și Biarritz. În replică, Cătălin aduce vibe-ul de la Cluj și TIFF, întâlnirea cu Ovidiu Schumacher și ediția specială cu Nadia Comăneci și Simona Halep. Plus: un gând de admirație pentru Dragoș Pătraru și o reflecție amară asupra crizei guvernamentale actuale. 00:43:32 - Football Leaks, Liverpool și Elena Udrea. 02:51:31 - Spuma Filelor: Recomandări de carte care merită toată atenția dumneavoastră. Volumele analizate în această ediție: „Povestea nemuririi" - Andrei Cornea, „Placebo". Chirurgii în căutarea nemuririi" - Cătălin Vasilescu, „În gură de șarpe" - Cristian Tudor Popescu și „Scriu Iliada" - Pierre Michon. 03:12:49 - Vânătorile Dianei Popescu: Agenda culturală a săptămânii 03:32:03 - Oale, ulcele și tigăi: Tapas și delicii culinare de la Adi Hădean și de la Cluj

The placebo effect is a phenomenon in which a person's symptoms or well-being improve after receiving a fake treatment that has no specific or intrinsic effect on their condition. For example, a person may feel less pain after taking a sugar pill that they believe is a painkiller, or they may feel more energetic after receiving an injection of saline solution that they think is a vitamin. The placebo effect is not just about positive thinking or wishful thinking. It involves complex psychological and physiological mechanisms that are not fully understood. How does the placebo effect work? What are the benefits of the placebo effect? What are the limitations of the placebo effect? In under 3 minutes, we answer your questions! To listen to the last episodes, you can click here : ⁠⁠Could AI ever be able to offer therapy?⁠⁠ ⁠⁠What is plasticrust, the latest concerning form of pollution?⁠⁠ ⁠⁠Why don't scars disappear?⁠⁠ A Bababam Originals podcast.A podcast written and realised by Amber Minogue. First Broadcast the 25/03/2023 Learn more about your ad choices. Visit megaphone.fm/adchoices

Ce 23 juin, Marjorie Hache met à l'honneur Led Zeppelin, Thin Lizzy, T. Rex, The Four Tops, Amy Winehouse, Neil Young and Crazy Horse, Daft Punk, Radiohead, Arctic Monkeys, Queen, Fleetwood Mac, Placebo, Moodoïd et The Who. L'animatrice célèbre par ailleurs le 64e anniversaire de Steve Shelleyavec "My Friend Goo", soulignant son parcours depuis son arrivée à New York jusqu'à son rôle de batteur emblématique au sein de Sonic Youth. Suede donne le coup d'envoi des nouveautés avec "Emotionally Unavailable", issu de la réédition de son disque "Antidepressants". Tahiti 80 révèle "Too Much Too Fast Too Soon", tandis que Jack White, Korn, Deep Purple et la Néo-Zélandaise Gin Wigmore complètent le tableau. La primeur de la soirée met en lumière Schnallo, projet dark wave de Kimi Recor, qui offre l'envoûtant "Doom Generation", aux sonorités électroniques ancrées dans les années 80. L'album de la semaine s'attarde sur "Castle Park", le tout nouveau disque de Graham Coxon, guitariste de Blur, dont on découvre la charmante pépite "There's A Little House". Enfin, pour la reprise du jour Muse s'approprie avec grandiloquence et théâtralité le mythique "Feeling Good", popularisé par Nina Simone en 1965. Suede - Emotionally Unavailable Led Zeppelin - Heartbreaker Sonic Youth - My Friend Goo Eiffel - À Tout Moment La Rue Thin Lizzy - Dancing In The Moonlight Four Tops - Reach Out I'll Be There Amy Winehouse - You Know I'm No Good Graham Coxon - There's A Little House T. Rex - Get It On Neil Young & Crazy Horse - Break The Chain Daft Punk - Robot Rock Tahiti 80 - Too Much Too Fast Too Soon Muse - Feeling Good Radiohead - Nude Arctic Monkeys - R U Mine? Gin Wigmore - Beautiful Mess Queen - Hammer To Fall Korn - Here To Stay Deep Purple - Arrogant Boy Fleetwood Mac - Go Your Own Way Placebo - This Picture Schnallo - Doom Generation The B-52's - Planet Claire Moodoïd - Heavy Metal Be Bop 2 The Who - My Generation Jack White - Dollar Bill All Them Witches - InternetHébergé par Audiomeans. Visitez audiomeans.fr/politique-de-confidentialite pour plus d'informations.

Welcome to another life-focused edition of Beats, Vines & Life. Today, MJ Towler sits down with renowned entrepreneur, teacher, and bestselling author Seth Godin. Known for his game-changing books like Purple Cow, Tribes, and This Is Marketing, Seth Godin has shaped the thinking of marketers, creators, and leaders around the world. In this episode, the conversation explores the intersection of marketing, storytelling, connection, and lifestyle—diving deep into why stories matter in the world of wine, how meaning and community elevate experiences, and the real power behind the premium price tag on that special bottle. From wine glasses and chocolate bars to placebos and permission-based marketing, get ready for practical wisdom and insight on building trust, finding your tribe, and living a life—and creating products—that truly matter. Pour a glass, settle in, and enjoy a conversation about creativity, generosity, and the courage to ship your best work.Subscribe to Seth's Blog!Follow Seth on IG!____________________________________________________________Until next time, cheers to the mavericks, philosophers, deep thinkers, and wine drinkers! Grenache Fest is BACK!!! Grenache Fest is coming to Waitsburg, Washington, bringing with it a focused, celebratory spotlight on one of the world's most important and expressive grapes. This year, we will start with a blind tasting seminar hosted by MJ Towler, Chauncey Arkfeld, and Michael Alberty, followed by smaller breakout sessions across town.Subscribe and give Beats Vines and Life a five-star review on whichever platform you listen to.For insider info from MJ and exclusive content from the show, sign up at blackwineguy.comFollow MJ @blackwineguyFollow Beats Vines and Life @beatsvinesandlifeFollow Totally Biased Wine Reviews on IGSign up for Totally Biased Wine Reviews Hosted on Acast. See acast.com/privacy for more information.

Chug your pumpkin juice and let's win that Quidditch match! Join as Karoline, Sophia, Taavi, and our guest Ella discuss Chapter 14 of Harry Potter and the Half-Blood Prince: Felix Felicis! Join the discussion on our website In this episode: The romantic drama of the chapter splits our panel An in-depth enumeration of all the ways Ron sucks Harry is a bad friend Hermione doesn't get enough credit for her Quidditch passion Ginny tells the whole castle that Ron makes out with his aunt Viktor Krum's Quidditch prowess lives rent-free in Ron's head WON WON!! Ron's Inauguration into the Society of Filthy Hippogryffs Would Felix Felicis make a good anxiety medication? For more from our guest Ella: @ellaheipt on Instagram Contact: Website: https://threebroomstickspod.com/ Facebook: https://www.facebook.com/threebroomstickspod/ Instagram: https://www.instagram.com/threebroomstickspodcast/ Twitter: https://twitter.com/threebroompod Email: 3broomstickspod@gmail.com Patreon: https://www.patreon.com/3broomsticks 

Your body is not a cage for your spirit. It is, in fact, the key to your awakening. In many spiritual communities, the term "meatsuit" gets tossed around. It's become shorthand for the idea that our physical bodies are just temporary vehicles and obstacles we need to transcend.  But that perspective is wrong, and it's actually keeping you from the very spiritual growth you're seeking! In this livestream, we're dismantling the meatsuit fallacy and exploring what spiritual traditions, ancient wisdom, and modern research reveal about the incredible intelligence of the human body:

“Safety is at the root of healing. We can't heal unless we feel safe because our nervous system won't function if it thinks it's under threat.” – Dr. David RabinHigh performers have been conditioned to treat chronic stress as a badge of honor.But constantly running your mind and body on empty isn't a strategy for elite success—it's a direct path to burnout. Our guest today has the blueprint to build a foundation of physiological safety and recovery.Dr. David Rabin is a board-certified psychiatrist and neuroscientist who specializes in helping patients heal from chronic stress and trauma where traditional medicine fell short.As the co-founder of Apollo Neuroscience, he developed the world's first wearable technology that actually trains your nervous system to calm down and focus in real time.In this episode:• Why your brain treats a packed inbox the exact same way it treats a physical threat.• The biological reason your body blocks healing and optimization when you are red-lining.• How mastering your own stress response gives your kids the single greatest unfair advantage for their future.• Practical micro-habits to signal safety to your brain, protect your mental clarity, and unlock a new level of energy during a high-stakes workday.Let's WIN THE DAY with Dr. David Rabin!_Show links:

If you enjoy this episode, we're sure you will enjoy more content like this on The Occult Rejects.  In fact, we have curated playlists on occult topics like grimoires, esoteric concepts and phenomena, occult history, analyzing true crime and cults with an occult lens, Para politics, and occultism in music. Whether you enjoy consuming your content visually or via audio, we've got you covered - and it will always be provided free of charge.  So, if you enjoy what we do and want to support our work of providing accessible, free content on various platforms, please consider making a donation to the links provided below.  Thank you and enjoy the episode!Links For The Occult Rejectshttps://linktr.ee/theoccultrejectsOccult Research Institutehttps://www.occultresearchinstitute.org/Cash Apphttps://cash.app/$theoccultrejectsVenmo@TheOccultRejectsBuy Me A Coffeebuymeacoffee.com/TheOccultRejectsPatreonhttps://www.patreon.com/TheOccultRejectsBibliographyThe Mechanics of Magick: Singing Bowls and the Ritual Physics of ResonanceCore Singing Bowl ResearchStanhope, Jessica, and Philip Weinstein. “The Human Health Effects of Singing Bowls: A Systematic Review.” Complementary Therapies in Medicine 51 (2020): 102412. Use for the honesty frame: promising findings around mental health and cardiovascular measures, but limited evidence and need for stronger study design.Cai, Yiqing, Guo-Yan Yang, Yibo Liu, Xiang-yun Zou, Heng Yin, Xinyan Jin, Xue-han Liu, Chenlu Wang, Nicola Robinson, and Jian-Ping Liu. “Therapeutic Effects of Singing Bowls: A Systematic Review of Clinical Studies.” Integrative Medicine Research 14, no. 2 (2025): 101144. Use for the newer clinical overview. Important correction: this appears as 101144, not 101176. Good for anxiety, depression, sleep quality, cognition, autistic behavior, and EEG-related outcomes while still keeping the evidence cautious.Lin, F. W., et al. “Effects of Tibetan Singing Bowl Intervention on Psychological and Physiological Health in Adults: A Systematic Review.” 2025. Useful as another recent review angle, especially for psychological health, physiological measures, HRV, and brainwave-related discussion. Keep it secondary behind Stanhope and Cai.Landry, Jayan Marie. “Physiological and Psychological Effects of a Himalayan Singing Bowl in Meditation Practice: A Quantitative Analysis.” American Journal of Health Promotion 28, no. 5 (2014): 306–309. Use for the controlled relaxation study: 51 participants, randomized crossover design, singing bowl exposure or silence before directed relaxation.Goldsby, Tamara L., Michael E. Goldsby, Mary McWalters, and Paul J. Mills. “Effects of Singing Bowl Sound Meditation on Mood, Tension, and Well-Being: An Observational Study.” Journal of Evidence-Based Complementary & Alternative Medicine 22, no. 3 (2017): 401–406. Use for reductions in tension, anger, fatigue, depressed mood, anxiety, and stress after singing bowl meditation. Good, but frame as observational, not definitive.Rio-Alamos, Cristina, et al. “Acute Relaxation Response Induced by Tibetan Singing Bowl Sounds: A Randomized Controlled Trial.” European Journal of Investigation in Health, Psychology and Education 13, no. 2 (2023): 317–328. Use for Tibetan singing bowl treatment compared with progressive muscle relaxation and a waiting-list control in anxious nonclinical adults.Walter, Nina, et al. “Neurophysiological Effects of a Singing Bowl Massage.” Medicina 58, no. 5 (2022): 594. Use for EEG, ECG, and respiration during singing bowl massage; the authors interpret the results as a shift toward a more mindful or meditative state.Goldsby, Tamara L., et al. “Mood, Emotional, and Spiritual Well-Being Interrelationships.” Religions 13, no. 2 (2022). Useful follow-up for spiritual well-being, emotional interpretation, and how people understand sound-healing experiences.Sound, Anxiety, HRV, and Brainwave CautionMallik, Adiel, and Frank A. Russo. “The Effects of Music & Auditory Beat Stimulation on Anxiety: A Randomized Clinical Trial.” PLOS ONE 17, no. 3 (2022): e0259312. Use this carefully for the broader point that sound-based treatments can reduce somatic and cognitive state anxiety. Do not use it as proof that singing bowls automatically entrain brainwaves.Ingendoh, Ruth Maria, Ella S. Posny, and Angela Heine. “Binaural Beats to Entrain the Brain? A Systematic Review of the Effects of Binaural Beat Stimulation on Brain Oscillatory Activity, and the Implications for Psychological Research and Intervention.” PLOS ONE 18, no. 5 (2023): e0286023. Very useful caution source. Use it when warning against overclaiming “brainwave entrainment” and frequency-healing claims.Vilímek, et al. 2022. Low-frequency sound / HRV / vibroacoustic-related research. Use cautiously if you want to discuss low-frequency vibration, body sensation, and autonomic response. I'd keep this as a secondary source unless you want a dedicated paragraph on vibroacoustics.Physics, Resonance, and CymaticsTerwagne, Denis, and John W. M. Bush. “Tibetan Singing Bowls.” Nonlinearity 24, no. 8 (2011): R51–R66. Use for the physics section: wall vibrations, water-surface waves, Faraday-wave effects, droplet motion, and the visible demonstration of resonance.Jenny, Hans. Cymatics: A Study of Wave Phenomena and Vibration. Newmarket, NH: MACROmedia, 2001. Use carefully for visual sound-pattern history. Good for imagery and occult imagination, but don't overuse it as clinical proof.Rossing, Thomas D. The Science of Sound. 3rd ed. San Francisco: Addison Wesley, 2002. Useful general acoustics source for resonance, overtones, vibration, sound waves, and instrument physics.Sound Baths, Wellness Culture, and Modern RitualSobo, Elisa J. “Sound Baths, Trauma Talk, and the Wellness Paradox in the USA.” Medical Anthropology 43, no. 5 (2024): 367–382. Excellent for the modern sound-bath/wellness-culture angle, especially trauma language, nervous-system talk, ritual performance, and how providers frame sound baths.Sobo, Elisa J. “A Beginner's Guide to Sound Baths — What They Are, How to Choose a Good One and What the Research Shows.” The Conversation (2024). Useful for accessible show-note language and ethical/practical framing.Sobo, Elisa J. “Healing Vibrations.” Anthropology News 64, no. 5 (2023): 28–32, 49. Good anthropology/public-facing source for sound healing and wellness culture.Tibetan Singing Bowls, History, and Cultural CommodificationGrimes, Samuel. “Where Did ‘Tibetan' Singing Bowls Really Come From?” Tricycle (2020). Use for the contested-history section. Strong source for questioning popular origin stories around “Tibetan” singing bowls.Joffe, Ben. “Anthropology and Tibetan Buddhism / Cultural Commodification / Tibetan Mystique.” 2015. Use for the larger argument about how Tibetan/Himalayan aura gets packaged in Western spiritual markets. Good support for the “Tibet as imagined storehouse of hidden wisdom” point.Scheidegger, Daniel A. “Tibetan Ritual Music.” Use for actual Tibetan Buddhist ritual sound: bells, cymbals, long horns, drums, chant, and liturgical soundscape. This helps separate real Tibetan ritual sound from overblown modern singing-bowl mythology.Lopez, Donald S. Prisoners of Shangri-La: Tibetan Buddhism and the West. Chicago: University of Chicago Press, 1998. Excellent support for Western romanticization of Tibet.Bishop, Peter. The Myth of Shangri-La: Tibet, Travel Writing, and the Western Creation of Sacred Landscape. Berkeley: University of California Press, 1989. Very useful for the “Tibet as fantasy geography” angle.Ritual, Sound, and Religious ExperienceEliade, Mircea. Shamanism: Archaic Techniques of Ecstasy. Princeton: Princeton University Press, 1964. Use carefully. Good for altered-state technologies and ritual sound/trance, but don't treat it as the final word on shamanism.Rouget, Gilbert. Music and Trance: A Theory of the Relations Between Music and Possession. Chicago: University of Chicago Press, 1985. Excellent for sound, music, trance, possession, rhythm, and ritual performance.Becker, Judith. Deep Listeners: Music, Emotion, and Trancing. Bloomington: Indiana University Press, 2004. Strong source for deep listening, music, emotion, trance, and the body.Husserl, Edmund. On the Phenomenology of the Consciousness of Internal Time. Useful if you want to get philosophical about tone, decay, waiting, and how sound reveals time.Ihde, Don. Listening and Voice: Phenomenologies of Sound. Albany: SUNY Press, 2007. Good for sound as experience, listening, voice, and embodied perception.Placebo, Meaning Response, and Healing RitualMoerman, Daniel E. Meaning, Medicine and the “Placebo Effect.” Cambridge: Cambridge University Press, 2002. Use for “meaning response” instead of treating placebo as “fake.”Benedetti, Fabrizio. Placebo Effects: Understanding the Mechanisms in Health and Disease. Oxford: Oxford University Press, 2009. Useful for placebo mechanisms, expectation, physiology, and therapeutic context.Kaptchuk, Ted J., and Franklin G. Miller. “Placebo Effects in Medicine.” New England Journal of Medicine 373 (2015): 8–9. Good short medical source for placebo effects as real psychobiological phenomena.Csordas, Thomas J. The Sacred Self: A Cultural Phenomenology of Charismatic Healing. Berkeley: University of California Press, 1994. Useful for healing, embodiment, ritual, and religious experience.Embodied Cognition, Extended Mind, and Ritual ToolsClAlso want to remind people about the website, if you're into reading we have tons of information by multiple contributors, and we got t-shirts up on the site if you're interested. Fun fact, the art is all based on the eyeball. A

Jo Marchant is a science journalist and podcast host, and also the author of several books. Her latest works include In Search of Now: The Science of the Present Moment and Cure: A Journey into the Science of Mind Over Body. Greg and Jo discuss the shared threads across her work: a long view of the history of thought and the mind–body relationship. Jo explains how physics and neuroscience challenge a single objective “now,” describing perception as an active predictive process shaped by past experience and expectations, with examples from illusions and sensory priming. They discuss predictive coding, placebo effects, psychoneuroimmunology, anxiety as attention-weighted error monitoring, and how mindfulness and awe can rebalance attention and reduce stress. Jo also contrasts flow with mindfulness, explores choking and depersonalization-derealization as over-attention to self, and critiques medicine's structural barriers to integrating context and meaning.  *unSILOed Podcast is produced by University FM.* Episode Quotes: Why once you hear it, you can't unhear it 14:49: There are other times when we can consciously override things where, for example, if you hear, I don't know, a record being played backwards or something, and it might not, you know, sound like anything, and you're told that actually there's a satanic message hidden within the sound, and you see written down a transcript of what the voice is meant to be saying. So you're listening for it, and so that's adjusting the filtering that your brain's doing. And so it will sort of tune down some things, tune up other things, and then suddenly the voice pops out and you hear it clear as day, and you think, “How on earth did I not hear it before?” You can't unhear it. Perception is prediction 09:59: Everything that we perceive is being shaped by everything that we have perceived in the past and everything that we expect about the future. There's no differentiation between real physical pain and psychological pain. 22:20: There's no differentiation between real physical pain and psychological pain. It's all exactly the same pain. All of that pain or fatigue or whatever it is , is that integrated output of the brain taking everything into account that it knows, and then it's giving you this warning signal, and it's that sort of overall picture. And it's the exact same pain, whether that is purely coming from you've just broken your leg or something, or whether it's coming from a lifetime of stress and trauma that's telling you that you're in a really dangerous situation and something is wrong. The pain is going to feel just as real. Show Links: Recommended Resources: Heraclitus Placebo Depersonalization-Derealization Disorder (DPDR) Guest Profile: JoMarchant.com Wikipedia Page Social Profile on Instagram YouTube Channel Guest Work: Amazon Author Page In Search of Now: The Science of the Present Moment The Human Cosmos: Civilization and the Stars Cure: A Journey into the Science of Mind Over Body Decoding the Heavens The Shadow King: The Bizarre Afterlife of King Tut's Mummy Where The Wild Thoughts Are Podcast Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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Three more digoxin trials, yet another GLP-1 drug on the horizon, vagal nerve stimulation, trial inside baseball, and more on lipid guidelines are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I More About Low-dose Digoxin in HF — The DECISION Trial(s) DECISION Trial https://www.nature.com/articles/s41591-026-04406-6 Digitalis Glycosides in HF — JAMA Meta-Analysis https://jamanetwork.com/journals/jama/fullarticle/2848972 DIGIT-HF Trial https://www.nejm.org/doi/10.1056/NEJMoa2415471 RADIANCE Trial (1993) https://www.nejm.org/doi/full/10.1056/NEJM199307013290101 DECISION Withdrawal Study https://doi.org/10.1093/eurheartj/ehag385 Digoxin Discontinuation vs Continuation in Chronic HF https://doi.org/10.1016/j.amjcard.2007.02.099 II Yet another GLP-1 Drug Announced this Week Lillly News Release on Retatrutide https://investor.lilly.com/news-releases/news-release-details/lillys-triple-agonist-retatrutide-delivered-powerful-weight-loss III A Big Story in HF Science – Vagal Nerve Stimulation in HFrEF ANTHEM HFrEF trial https://doi.org/10.1016/j.jacc.2026.03.040 Editorials An Unfinished ANTHEM https://doi.org/10.1016/j.jacc.2026.04.033 When Trials Stop Prematurely https://doi.org/10.1016/j.jacc.2026.03.039 IV Lipid Guideline News Lipid Guidelines: Four Major Concerns https://www.medscape.com/viewarticle/lipid-guidelines-four-major-concerns-2026a1000fim Editorial: Time to Move Beyond the Statin Nocebo Effect  https://www.jacc.org/doi/10.1016/j.jacc.2026.04.002 Correspondence: SAMSON N-of-1 Trial of Statin, Placebo, or No Treatment https://www.nejm.org/doi/full/10.1056/NEJMc2031173 You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net

Your relationships are reshaping your biology in ways that diet and exercise alone cannot fix, and the science behind it will change how you think about longevity, metabolism, and what it actually means to be healthy. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Dr. Molly Maloof, a physician and one of the most innovative voices in personalized medicine, functional medicine, and human performance. Since 2012, she has advised or consulted for over 50 companies across digital health, consumer health, and biotechnology. She pioneered a course on healthspan at Stanford University and founded Adamo Bioscience, a company dedicated to unlocking the science of love as a pathway to healing and human connection. Dr. Maloof brings a rare combination of clinical depth, biohacking credibility, and entrepreneurial range to one of the most overlooked conversations in longevity. Together, Dave and Dr. Maloof dig into the neurobiology of love and attachment, the hormonal drivers of the sex drive and pair bonding, and how chronic isolation wrecks your metabolism at the cellular level. They explore the cell danger response and how toxic relationships, mold exposure, and trauma can lock your cells into a self-protection mode that blocks healing. They also cover psychedelics as hormetic tools, oxytocin as nature's medicine, the placebo response, peptide therapy for mitochondrial repair and anti-aging, and why regenerative medicine is about to rewrite the rules of human lifespan. If you are serious about biohacking your body from the inside out, this episode is essential. You'll Learn: Why human connection is a biological necessity, not a lifestyle preference, and what isolation does to your mitochondria and metabolism How the three neurobiological drives of sex, romantic love, and attachment are wired into your hormones and what happens when they go wrong What the cell danger response is, why it gets stuck, and which peptides, supplements, and therapies help break the cycle How oxytocin drives wound healing, immune function, and the placebo response Why psychedelics work as hormetic love drugs and how they reproduce the neurobiology of romantic love The top peptides for mitochondrial repair, brain optimization, and telomere biology Why Dave and Dr. Maloof believe we have already reached longevity escape velocity How AI is accelerating precision medicine, protein folding breakthroughs, and the future of anti-aging therapeutics Why fasting, breathwork, neurofeedback, and somatic therapies all converge on the same biological reset mechanism How to build the adaptive capacity and bioenergetic reserves to bounce back from anything Thank you to our sponsors! - Danger Coffee | Grab yours at DangerCoffee.com and use code DAVEPOD at checkout for 15% off. - Amp | If you're ready to make fitness fit into your life, go to amp.ai to check it out - Puori | Go to Puori.com/DAVE or use code DAVE at checkout to get 32% off your Puori Fish Oil subscription. You save more than $18 - Our Place | Stop cooking with toxic cookware and upgrade to Our Place today. With a 100-day risk-free trial, plus free shipping and returns, you can experience this game-changing cookware with zero risk. Visit: fromourplace.com/DAVE Use code: DAVE for 10% off sitewide Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Dr. Molly Maloof, Adamo Bioscience, Stanford University, personalized medicine, functional medicine, healthspan, longevity, biohacking, human performance, anti-aging, regenerative medicine, longevity escape velocity, cell danger response, mitochondria, mitochondrial health, oxytocin, vasopressin, dopamine, serotonin, neurobiology of love, attachment theory, pair bonding, sex drive, hormone replacement therapy, testosterone, estrogen, menopause, andropause, libido, female sexual dysfunction, relationship biology, social health, isolation, community, co-regulation, trauma healing, psychedelics, MDMA, psilocybin, ibogaine, ayahuasca, hormetic stress, social hormesis, neurofeedback, 40 Years of Zen, breathwork, nervous system regulation, HPA axis, cortisol, mast cell activation, histamine, long COVID, mold exposure, phospholipid therapy, glutathione, vitamin C, BPC-157, TB500, SS31, epothilone, SELANK, SEMAX, BDNF, telomere biology, telomerase, peptides, GLP-1, placebo response, wound healing, metabolism, continuous glucose monitoring, gut health, AI, precision medicine, supplements, brain optimization, neuroplasticity Resources: • Grab Molly's Book The Spark Factor: https://www.amazon.com/Spark-Factor-Supercharging-Optimizing-Feeling/dp/0063207206 • Learn More About Dr. Molly's Work: https://drmolly.co/ • Visit Your Healthspan Journey: https://yourhealthspanjourney.mystrikingly.com/ • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 00:28 – Intro 01:39 – COVID Isolation & Its Effects 03:11 – Science of Love & Hormones 04:24 – Psychedelics & Love Chemistry 09:22 – Cell Danger Response 11:07 – AI, Tech & Human Connection 13:20 – Social Connection as Medicine 20:50 – Placebo, Care & Psychedelics 24:49 – Altered States & Healing Modalities 30:09 – Peptides & Longevity Drugs 35:44 – Mast Cell & Personal Health Challenges 43:46 – Regenerative Medicine & The Future 46:17 – Longevity Escape Velocity 50:05 – Outro See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Support the sponsors to support the show!Protect your family with life insurance from Ethos. Get up to $3 million in coverage in as little as 10 minutes at https://ethos.com/soder Application times may vary. Rates may vary.https://www.ethos.com/?utm_source=arm&utm_medium=podcast&utm_campaign=soderStop putting off those doctors appointments and go to Zocdoc.com/SODER to find and instantly book a doctor you love today. Thanks Zocdoc for sponsoring this message.https://www.zocdoc.com/?utm_medium=audiopodcast&utm_campaign=soderRight now get up to 60% off your Babbel subscription – at Babbel.com/SODER Get up to 60% off @https://www.babbel.com/pages/en-us/eg_podcast_flags_ame_usa-en?utm_source=podcast&utm_medium=offline&utm_content=podcast&mt_agency=oxfordroad&mt_region=usa&utm_campaign=Soder&ad_type=hostread&mt_template=89624c3c3c274a77ba63128d19e25b6aif you like your money, Mint Mobile is for you. Shop plans at MINT MOBILE dot com slash SODER. That's MINTMOBILE.com/SODERDISCLAIMER [READ VERBATIM]: Upfront payment of $45 for 3-month 5 gigabyte plan required (equivalent to $15/mo.). New customer offer for first 3 months only, then full-price plan options available. Taxes & fees extra. See MINTMOBILE for details.https://www.mintmobile.com/?utm_source=podcast&utm_medium=audio&utm_campaign=mint_podcast&utm_content=soder&dnfemfkahqkdlf=soder The Golden Retriever of Comedy Tour is coming to your city!Get tickets at https://www.dansoder.com/tourJune 1-2 Key West,FLJune 5 - Newark,NJJune 13 - Mill Valley,CA - Special TapingJuly 9-11 Batavia,ILJuly 16-18 Stamford,CTJuly 31 - August 1 - Albany,NYAugust 13-15 Baltimore,MDAugust 20-22 Spokane,WASeptember 18-19 Manchester,CTOctober 2-3 Bernalillo,NMOctober 22-24 Calgary,ABNovember 5-7 Salt Lake City,UTDecember 10-12 Rochester,NYFollow Shane Mausshttps://www.youtube.com/watch?v=dHh3OSbTcWMhttps://www.instagram.com/shane_mauss/?hl=enhttps://www.facebook.com/shanecomedyfan/https://www.shanemauss.com/PLEASE Drop us a rating on iTunes and subscribe to the show to help us grow.https://podcasts.apple.com/us/podcast/soder/id1716617572Connect with SoderTwitter: https://Twitter.com/dansoderInstagram: https://www.instagram.com/dansoderTiktok: https://www.tiktok.com/@dansodercomedyFacebook: https://www.facebook.com/dansoderYoutube: http://www.youtube.com/@dansoder.comedy#dansoder #standup #comedy #entertainment #podcastProduced by  Mike Lavin     https://www.instagram.com/thehomelesspimp/?hl=en

“Placebo effects are real and mind-body effects are real, and there's a fairly large scientific literature on these things,” says Joshua W. Brown, Ph.D. Brown is a professor of Psychological and Brain Science at Indiana University, where he directs the Cognitive Control Lab. He also co-founded the Global Medical Research Institute With decades of experience in computational neuroscience and over 79 peer-reviewed publications, he brings the same rigorous scientific methodology to extraordinary claims of healing that he applies to understanding the brain. 00:00 - A neuroscientist's brain tumor diagnosis 07:29 - Prayer with expectation 10:43 - The biology of belief 12:13 - Inside the Global Medical Research Institute 17:14 - Even known placebos still work 20:27 - The science of miracles  24:10 - Conversion disorders & the mind-body line 32:02 - The brain is a prediction machine 38:02 - How chronic stress writes itself into the body 41:18 - Why "just believe" doesn't work 43:22 - Healing happens in community 47:16 - When neuroscience met the Dalai Lama 50:26 - The morning practice that grounds his day Referenced in the episode:  To learn more about Brown, visit his website: https://joshbrownneuro.com/  Buy Brown's book here: https://a.co/d/07qL3LKj  To learn more Brown's research, or to report your own miracle, visit the Global Medical Research Institute website: https://www.globalmri.org/ We hope you enjoy this episode, and feel free to watch the full video on YouTube! Whether it's an article or podcast, we want to know what we can do to help here at mindbodygreen. Let us know at: podcast@mindbodygreen.com. Learn more about your ad choices. Visit megaphone.fm/adchoices

In this video, Dr. Ruscio discusses 8 benefits of taking butyrate, a fat molecule with gut and systemic healing properties. Butyrate is produced by gut bacteria, but it is often low in different chronic health conditions. Supplementation has been shown to improve a variety of gut conditions, including IBS, IBD, and SIBO, as well as chronic inflammation and brain health. Doctor Ruscio also discusses some simple dietary strategies to increase butyrate production naturally.    ✅ Start healing with us! Learn more about our virtual clinic:  https://drruscio.com/virtual-clinic/  

Over 30 million Americans have been told a 19 billion dollar lie. Find out what doctors don't tell you about SSRI side effects, antidepressant effectiveness, and antidepressant risks that affect more people than you think. 0:00 Introduction: The 19 billion dollar lie1:12 Irving Kirsch and medical research bias2:09 Hamilton Depression Scale 2:59 Placebo vs. drug study for antidepressant effectiveness4:16 Antidepressant side effects4:33 Post-SSRI sexual dysfunction and emotional blunting5:49 Antidepressants and the placebo effect explained7:38 Natural antidepressants Download Dr. Berg's Free Daily Health Routine: https://drbrg.co/45qtO07Antidepressant effectiveness may be overstated. Irving Kirsch examined clinical trials on antidepressants and found that around 78% of them were unpublished, rewritten, or contained inflated results.The “gold standard” for measuring depression is the Hamilton Depression Rating Scale (HAM-D), which relies on subjective reporting and was not originally created to diagnose depression.In placebo-controlled trials, antidepressants did not significantly improve depression more than a sugar pill. A good night's sleep can improve the symptoms of depression significantly more than medication. Antidepressants come with a black box warning and many other side effects, including the following:• Sexual dysfunction • Post-SSRI sexual dysfunction • Emotional blunting• Discontinuation syndrome• Insomnia• Nausea• Anxiety• DepressionExercise, St. John's wort, omega-3s, and adequate sleep can help improve the symptoms of depression naturally. Dr. Eric Berg DC Bio:Dr. Berg, age 61, is a chiropractor who specializes in Healthy Ketosis & Intermittent Fasting. He is the Director of Dr. Berg Nutritionals and author of the best-selling book The Healthy Keto Plan. He no longer practices, but focuses on health education through social media.Disclaimer: Dr. Eric Berg received his Doctor of Chiropractic degree from Palmer College of Chiropractic in 1988. His use of “doctor” or “Dr.” in relation to himself solely refers to that degree. Dr. Berg is a licensed chiropractor in Virginia, California, and Louisiana, but he no longer practices chiropractic in any state and does not see patients, so he can focus on educating people as a full-time activity, yet he maintains an active license. This video is for general informational purposes only. It should not be used to self-diagnose, and it is not a substitute for a medical exam, cure, treatment, diagnosis, prescription, or recommendation. It does not create a doctor-patient relationship between Dr. Berg and you. You should not make any change in your health regimen or diet before first consulting a physician and obtaining a medical exam, diagnosis, and recommendation. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition.

Amy thought she was killing it in Pilates…turns out the praise wasn't just for her. There were 3 Amys in class. Kat is pregnant and the listener calls and emails are already pouring in…including one from a listener who is pregnant at the exact same time. Amy shares 5 small ways to rebuild trust in yourself when you're not sure you can. Plus, Victorian-inspired phrases for dealing with difficult men that are so good you'll want to memorize them. Get some Feeling Things merch by clicking HERE! (FeelingThingsPodcast.com) Sign up for the Feeling Things newsletter HERE! Watch us on Youtube HERE! Call and leave a voicemail: 877-207-2077 Email: heythere@feelingthingspodcast.com HOSTS: Amy Brown // RadioAmy.com // @RadioAmy Kat Van Buren // threecordstherapy.com // @KatVanburenSee omnystudio.com/listener for privacy information.