Podcasts about tbis

Dr. Deb Muth 00:00:09 Hi there, how are you? Bob Miller 00:00:10 Excellent! Pedaling as fast as humanly possible, but doing okay. Dr. Deb Muth 00:00:14 Good, good. Well, I’m looking forward to our conversation today. This should be amazing. Bob Miller 00:00:20 Yeah, it should be a lot of fun. Dr. Deb Muth 00:00:22 Yeah, anything that’s off-limits for you in, our conversation? Bob Miller 00:00:28 No. Dr. Deb Muth 00:00:29 Okay, anything you want me to make sure we cover for you? Bob Miller 00:00:33 Well, I mean, is it okay if we put a little plug-in for our software? Dr. Deb Muth 00:00:35 Absolutely. Bob Miller 00:00:36 Yeah. Dr. Deb Muth 00:00:37 Absolutely. Bob Miller 00:00:36 Yeah. Dr. Deb Muth 00:00:37 Absolutely. Bob Miller 00:00:38 Hey, can we… can we do a screen share? Yes, we can. Yeah, because I want to show you some maps, and… Dr. Deb Muth 00:00:43 Okay. Things like that, yeah, so… Perfect. So just let me know when you want to do screen share. Bob Miller 00:00:48 Okay. Dr. Deb Muth 00:00:49 And yeah, feel free to plug your software wherever you want to. Bob Miller 00:00:53 Okay, well, good. Let me pull up a, a slide for that, and give me one second, I just want to shut the door to my office to get the noise down. Dr. Deb Muth 00:01:01 No worries. Bob Miller 00:01:16 And, how should I refer to you? Dr. Debb? Dr. Muth, what do you like? Dr. Deb Muth 00:01:18 Dr. Deb is great, or Deb, either way, I’m pretty informal, so… Bob Miller 00:01:22 Yeah, and… Bob is fine for me. Okay. Yeah. Yeah, there you go. Why people feel like they need this, son. Special name, it’s like, seriously. Dr. Deb Muth 00:01:33 Right? I agree. Bob Miller 00:01:35 When I work with my clients, it’s like, Dr. Millison, just, just bop, just, just bop. Dr. Deb Muth 00:01:41 Yep, that’s how I am, too. Just call me Deb, it’s good. Dr. Deb Muth 00:01:44 They feel a little awkward with that, you know? They’re not used to that, but… Bob Miller 00:01:48 Alright. And you’re a naturopath, medical doctor. Dr. Deb Muth 00:01:52 A nastropathic doctor and a nurse practitioner. Oh, nice. Yeah, so I got the best of both worlds, right? Bob Miller 00:01:58 Yeah, damn. Okay. Alright, so here we go… There we go. Alright, so I got that ready, and then I will do a, I will do a screen share. I think you’re gonna really, appreciate what we’ve come up with. We’ve come up with the concept of, Cellular CPR. Dr. Deb Muth 00:02:23 Oh, nice! Bob Miller 00:02:24 And that is, construct the cell membrane, Protect the cell membrane. And restore it if it’s damaged. Dr. Deb Muth 00:02:32 Love that. Bob Miller 00:02:34 I love that. Yeah, so that’s what we’re focusing on, and then how, You know, we want to get to the point that, you know, most people think of genetics, they think of, like, 23andMe or Ancestry. Dr. Deb Muth 00:02:44 Yeah. Bob Miller 00:02:45 And then you have the professional geneticists who are looking at, you know, odd things that could create a disease. We’re looking at functional genomics. Dr. Deb Muth 00:02:54 Which is so much better. Bob Miller 00:02:56 Yeah. Are you familiar with what we do here, or… Dr. Deb Muth 00:02:58 A little bit, a little bit. So, it’ll be new to me, too, so I’m excited. Bob Miller 00:03:03 And how much time do we have? Dr. Deb Muth 00:03:04 We have an hour, give or take a little bit on either side. Do you have a hard stop anywhere? Bob Miller 00:03:10 No, no, I put a, I moved my clients around, and I don’t have anybody till, 3.30, so we’re good. Okay. Dr. Deb Muth 00:03:16 Perfect. Alright. Bob Miller 00:03:18 It’s like we’re getting started early as well, so… Dr. Deb Muth 00:03:19 Yeah, we’re getting started a little bit early, so that’s good. Bob Miller 00:03:22 Yeah, I just got my office cleaned up, so… Dr. Deb Muth 00:03:23 Okay, good. All right, are you all set to get started? Bob Miller 00:03:28 I’m good to go, my friend. Dr. Deb Muth 00:03:29 I’m gonna just record a little intro and a little bit of a, hook for people, and then we’ll get started. I’ll ask you to kind of tell us a little bit about yourself, and then we’ll just take this conversation wherever it’s supposed to go. Bob Miller 00:03:39 Okay, you got it. Dr. Deb Muth 00:03:40 Alright, sounds good. So what if the reason you’re not healing isn’t your diet, your supplements, or your labs, but it’s actually your genes? Dr. Bob Miller is uncovering how genetic variants, when combined with modern toxins, explain why some of us stay sick no matter what we try. Today, we’re talking genetic pathways, detox blocks, and the new science every wellness warrior needs to know. Welcome back to Let’s Talk Wellness Now, the show where we uncover the root causes of chronic illness, exploring cutting-edge regenerative medicine, and empower you to heal from the inside out. I’m Dr. Deb, your medical detective, and today, our guest, Dr. Bob Miller, is a true pioneer in functional genomics. He’s a board-certified traditional naturopath and the founder of Neutrogenetic Research Institute. And he’s the leading groundbreaking research on how genetic variants influence chronic illness, inflammation, and detoxification. His work has been recognized on international stages, uncovering links between genetic expression and conditions like Lyme disease, mast cell activation, or MCAS, and mitochondrial dysfunction. I’m so excited to talk to Dr. Bob today. He is gonna reveal some things that even I don’t know about, so I’m excited to learn alongside of you guys. So… Dr. Bob, let’s get started. Tell us a little bit about yourself, and kind of how you got on this journey. Bob Miller 00:05:04 Well, that’s, that’s interesting. I was sort of like a mid-career coming to the natural health field, because in my early 30s, I found myself with a severe case of ulcerative colitis. Bob Miller 00:05:15 And I was in the hospital for 21 days. probably within hours of death, pleading to death. And they told me I’ve got one option, and that is cut out the colon and wear a bag. Didn’t sound like a lot of fun. Dr. Deb Muth 00:05:27 Not an option I would want. Bob Miller 00:05:29 So, you know, the medical folks wasn’t real happy with me, but I said, yeah, I’d like to explore some alternative things.Never thinking that I’d get into this field, and then I just, you know, worked with some herbalists and things that I found absolutely fascinating. So, that’s how I got into this around 30 years ago. And, haven’t looked back since, and just having a… having a blast as we now move into how our genetics impacts things. So, that’s what we’re gonna… that’s what we’re gonna talk about today. Dr. Deb Muth 00:05:58 I’m excited to talk about this genetic thing. When you started over 30 years ago, what kind of patience and problems first inspired you to dig deeper into that root cause healing and kind of get into the genetic piece of it? Bob Miller 00:06:10 Sure. Well, you know, as a… now, I’m in a part of the country called Lancaster County, Pennsylvania, where there’s a lot of Amish and Mennonite, and they gravitate towards these things.So, this is their first thing to do, and that doesn’t work, then they’ll go other routes. So, you know, back then, we just saw typical, you know, a little tired, constipation. You know, a little bit of fatigue, arthritis, those kind of things. But things have changed dramatically over the years, as people are now getting more chronically sick. You know, it’s worse than it’s ever been. And what we’re finding is the, the culprits Primarily is mold exposure and Lyme disease. When people get those two together, they’re just… it’s an inflammatory cascade that nobody can seem to unravel. So that’s where we spend a lot of our time. And we’re also spending a lot of time looking at mental health, like ADD, ADHD. And, we give… this year I’ll be speaking at three autism conferences. And we can dig into that a little bit as to why we think we’re seeing such a dramatic increase. And aside from autism, that used to be 1 out of 1,000, now it’s 1 out of 33, or 23. You know, we’re also seeing dramatic increases in ADD, ADHD. People are stressed out. And today, I think we’ll have the time to actually go through and show how environmental factors combine with genetics to cause that to happen. So we’ll… we should have a fun visit here today. And today, I think we’ll have the time to actually go through and show how environmental factors combine with genetics to cause that to happen. So we’ll… we should have a fun visit here today. Dr. Deb Muth 00:07:37 This should be a fun visit. We can cover lots of topics. I am so excited. So, you founded Nutri Genetic Research Institute in 2015. What did you hope to accomplish, and what kind of surprised you in your findings so far about that? Bob Miller 00:07:51 Well, you know, let’s back up at what, you know, genetics is used for. Everybody’s familiar with 23andMe and Ancestry that, you know, tells you where your ancestors came from. Then you have your professional geneticists. I mean, these are people with a degree in genetics. And they’ll look for, you know, very odd sort of things that are prone to relate to a disease. So there are disease-related genetics. Well, in functional, we don’t look at either of those. We look at For example, how you’re breaking down your fats and utilizing them. How you’re recycling your glutathione. How you might be handling your iron. And none of those are disease-causing on their own.And none of those are disease-causing on their own. But when they pile up on you, and then combine that with environmental factors, that’s when things start to go south on us. So, that’s what we’re doing, we’re looking at patterns. And our first foray into this was, we did studies on Lyme disease. And our first foray into this was, we did studies on Lyme disease. So, we looked at, like, I think 50 people with Lyme disease. We looked at their genome. So, we looked at, like, I think 50 people with Lyme disease. We looked at their genome. And we found patterns that were more evident in those with Lyme. Now, this doesn’t… these genetics don’t mean you get Lyme, it just means if you get Lyme, you react worse to it. And we found patterns that were more evident in those with Lyme. Now, this doesn’t… these genetics don’t mean you get Lyme, it just means if you get Lyme, you react worse to it. So, as you know, some people get Lyme, they go on a round of antibiotics, and they’re done. So, as you know, some people get Lyme, they go on a round of antibiotics, and they’re done. Others have a little more struggle, and then others are struggling terribly for years. So there’s an old adage of genetics loads the gun, environment pulls the trigger. Dr. Deb Muth 00:09:14 Yeah, that is so true, and I think when we’re talking about Lyme and mold and things like that, we forget sometimes that our genetics can predispose us to be more sensitive to those things, and if we have genetic pathways where we don’t clear things properly, it’s harder for us to get them out of the body. And then you add on that whole rain barrel effect that we’ve always used as a functional medicine term, right? If the barrel’s half full, you’re okay. If it’s full, and now it’s spilling over, it’s a bigger problem. Have you guys found, too, that some of these environmental things actually are changing the genetics of people, or how they’re processing their own genetics? Bob Miller 00:09:53 Well, let’s go back to, Genetics 101. But we’ll go back a little bit further. So, what an interesting mechanism, what a miracle the body is. Bob Miller 00:10:03 Fats, carbohydrates, proteins, drink water, breathe air, expose the sunlight, and somehow everything gets made. I mean, when you just step back and think about that, it’s like, It’s pretty darn amazing. Dr. Deb Muth 00:10:15 I always tell women, you know, the fact that we get pregnant and we have healthy pregnancies and births is a miracle, because if we had to try to control that, that wouldn’t work so well. Bob Miller 00:10:25 Right. Well, that’s another miracle. These microscopic sperm and egg, human being, 9 months later, it’s like. But even inside of us. We are making our hair, our skin, our nails, our blood vessels, our ATP, our energy, it’s all being created. Well, that gets created by enzymes. So, enzymes take one substance, combine it with something else, and make something new. Then another enzyme comes along and does the same thing. Your DNA is the instructions on how to make the enzymes. So, when we are conceived. If it’s a, if it’s a female, of course, it’s the XX, the two chromosomes. You know, we’ve… everybody’s seen those… the genetics that… Listed pair. So, if it’s a female, the father donated the X enzyme. And the mother has no choice but to give the eggs, so that’s female. If the father donates the Y, you have a male that’s in chromosome number 1. Then 2 through 23 is the rest of the instructions on how to make enzymes. So, what can happen? We can get what are called SNPs, single nucleotide polymorphisms. And SNPs just mean that the instructions to make the enzyme’s not quite as good. So, if one parent gives a SNP on the making of an enzyme, The enzyme’s fine. It works. But, general rule of thumb, It may only work at 70-80% of efficiency. Now, a good analogy is think of an 8-cylinder and a 6-cylinder car. If parents give you good information, that’s like having an 8-cylinder car. If one parent gives you that snip, it’s like having a 6-cylinder car. Now, is a 6-cylinder car a fine car? Sure. It’ll get you from point A to point B, but it’s just going to have the power of an 8-cylinder. Then if both parents give you a SNP on the same enzyme, it may be 30-40%, and that’s like having a 4-cylinder car. Sits in the driveway, looks the same, puts gas in it, everything. But if you’ve got a 4-cylinder car. Probably not a good idea to go cross-country pulling a trailer behind you up and down mountains. Dr. Deb Muth 00:12:29 This is true. Bob Miller 00:12:32 So… We can get an 8-cylinder, 6-cylinder, or 4-cylinder enzyme. Now, if it’s not under a lot of stress, if that 4-cylinder car is just taking you to the bank and the grocery store. It’s just as good as an 8-cylinder car. But if you gotta pull that trailer, and there’s a lot of stress on it, being mountains, it’s gonna struggle. Now, there’s one other little caveat to this, and that is some genetic mutations are gain-of-function. They actually work faster. Now, we have enzymes that do all kinds of things. We have enzymes that make and recycle our antioxidants, but we also have enzymes that make inflammation. No, that’s a good thing, because if we get a virus or bacteria, if you didn’t make inflammation to kill it, well, we’d all die of infection. So, you know, we tend to think of free radicals as bad, antioxidants as good. They both play an important role. But interestingly, some of the major enzymes that make inflammation, they can be overactive. They can be turbocharged. And when they’re stimulated by environmental toxins, they overreact. Bob Miller 00:13:40 And therein lies the problem. When they overreact, we have a problem. Bob Miller 00:13:46 So, if we have genes that overreact when stimulated. And then the enzymes that take care of inflammation are underactive. Then you’re gonna be more inflamed. You know, the majority of people that, you know, come for functional medicine Or naturopathic help, or… Inflammation that they can’t seem to get under control. Dr. Deb Muth 00:14:06 Right. Bob Miller 00:14:07 And we will be, you know, during this hour, we’re going to look at some of the pathways that make that happen. So, what we can do then, we can’t change our genetics. When you’re conceived, that’s the hand you’re dealt. When your life would be over, if someone would take some tissue and measure, it’d be exactly the same as conception. Does it change. Bob Miller 00:14:28 The enzyme’s ability to do its job may be compromised. Because remember I said there’s a, the enzyme takes a cofactor. So an enzyme takes substance A, cofactor, make substance B. Well, if that cofactor’s not there, the enzyme’s not going to work either. So, you could have an 8-cylinder car, and if there’s no gas in it, it’s not going anywhere. So… It’s the strength of the enzyme, it’s the cofactor to do the A to B conversion. And that’s what we’re going to get into. So, many people say, well, where did these SNPs come from? Nobody knows for sure. Sometimes they’re what’s just called de novo, when the sperm and egg go together, the instructions get mixed up a little bit. We do believe a lot of it came from a long time ago, when we were almost wiped out by sexually transmitted diseases. And those STDs were altering the genes when the conception, in other words, when the sperm went into the egg, the STDs were interfering. And causing the problem, so… I often joke, if you want to blame somebody. Blame your great-great-great-great-great-great-great-grandparents for, being a bit promiscuous, so… Dr. Deb Muth 00:15:31 Yeah, for being… having a little too much fun, right? Bob Miller 00:15:35 So, we don’t know for sure, but, you know, there are some that, But most of the SNPs that we get inherit from our parents. So, if you look at a child. And you look at the SNPs. 99.9% of the time, it came from one of the parents. Dr. Deb Muth 00:15:50 In identical twins, do they have the exact same identical makeup? Bob Miller 00:15:54 Yep, Dr. Deb Muth 00:15:56 But not in fraternal twins, correct? Bob Miller 00:15:59 No, no, those could be different, Jeff. Dr. Deb Muth 00:16:00 It could be different because they have different sacs, they’re not sharing that same genetic makeup. Bob Miller 00:16:04 Yeah, so keep in mind, both your mother and your father have, you know, the two And so you get one from one parent, one from another. Dr. Deb Muth 00:16:13 So… Bob Miller 00:16:14 Interesting situation. I had, 3, 3 boys. And, we were looking at an enzyme related to breaking down oxalates. Now, the mother and father each had one SNP, and that’s called heterozygous. Three boys, and they all come together, they’re Amish boys, they’re a lot of fun. And I looked at their genomes, and the one boy didn’t have any SNPs at all. And one had won. And the other one had two. Dr. Deb Muth 00:16:41 Interesting. Bob Miller 00:16:42 So, we don’t quite know how these things get handed off, but with the parents each having one, you could have a child with none, one, or two. So, the one, his ability to break down oxalates, which is fine. The other one was slightly impaired, and the other one was dramatically impaired. So, you can have 3 children, and it all depends what the parents have. Now, if a parent has a homozygous, or 2 copies. And the other parent has nothing. Every child will have one. Okay. If both parents are homozygous, that they both have two, Every child will have two. Dr. Deb Muth 00:17:19 too. Bob Miller 00:17:20 Yes, so that’s the way it works, but, you know, but it’s somewhat rare that both parents are homozygous on an enzyme, but it can happen. Dr. Deb Muth 00:17:27 Do we think that infections today, like Lyme disease or mold exposure, things like that, if the parent, the woman, primarily, I’m thinking, is pregnant, and she actively has these infections. Can those infections affect the genetics, kind of like a past sexual transmission did where we thought back in the day? Bob Miller 00:17:47 Yeah, I… I mean, I’m not that much of a geneticist to answer that for sure, but my thought would be no, that at conception, the pattern’s made. Dr. Deb Muth 00:17:55 Okay. And then that’s… that’s the hand you’re dealt. Bob Miller 00:17:58 Yeah. So, I tell people we have good news and bad news. The good news is we can compensate for the weakness. The bad news is we can compensate for the weakness. Dr. Deb Muth 00:18:09 That is so very true. Bob Miller 00:18:11 Yeah, we can’t, because I often get asked, so we’ll do some things now, and we’ll check my genes again, and they’ll be better. It’s like, nope. Dr. Deb Muth 00:18:18 Oh, – – Bob Miller 00:18:19 You gotta play the hands you’re dealt, so… Dr. Deb Muth 00:18:21 That’s right. Bob Miller 00:18:22 You can test your genetics… if you’re looking at the same enzyme, you can test it every year. It’s not gonna change. It’s like the blueprint. Dr. Deb Muth 00:18:30 It’s good and bad, right? It’s the one test you only have to do once in your lifetime. Bob Miller 00:18:34 No, unless, you know, like, our. Dr. Deb Muth 00:18:36 All the time. Bob Miller 00:18:37 Yeah, now our test looks at, called the Functional Genomic Analysis Test of your genomic Resource. We look at 220,000 steps. Dr. Deb Muth 00:18:46 Wow, that’s a lot. Bob Miller 00:18:47 That’s not all of them. Dr. Deb Muth 00:18:49 Right. Bob Miller 00:18:50 So, maybe in the next year, we’re gonna come out with our third version of the chip. And then, if someone wants to get those new things that weren’t on it, they’d have to repeat. But whatever we measured is gonna stay the same. Dr. Deb Muth 00:19:03 That’s a lot of SNPs to look at. Bob Miller 00:19:05 Keeps us busy. Dr. Deb Muth 00:19:06 But there’s still, but there’s still SNPs that we. Bob Miller 00:19:09 That we’d like to have that we don’t have, so… Bob Miller 00:19:11 We started out with version 1 on our genetic test, then we worked with version 2, and we’re already compiling a list of what version 3 would look like. So if somebody has our version 2, And we’re saying, you know what, it’d be nice if we could see these, well, then you’d repeat, but it won’t change what you already know, so… Dr. Deb Muth 00:19:29 Got it, got it. So, when you started out, and you started looking at the research of Lyme disease and chronic infections, which detox pathways are most important for people who struggle with those conditions? Bob Miller 00:19:43 Okay. You know what might make sense as we do a screen share, and I’ll actually show you the pathway. Does that make sense? Bob Miller 00:19:48 Alright, so… let’s see if I… let me just press the share… Dr. Deb Muth 00:19:52 Yep, you should just be able to press share. Bob Miller 00:19:54 And… number 2. Okay. Are we seeing the screen there? Bob Miller 00:20:01 Okay. Dr. Deb Muth 00:20:02 So, this is a map that we made. Bob Miller 00:20:05 And by the way, this is not… All-inclusive of all the things we look at, but we believe this is a core issue. So, where we’re going to start here, there’s something called the microglia. And the microglia are glial cells. They’re in the brain and the central nervous system. And they’re very interesting little creatures, because most of the time, and this is just a drawing of what they sort of look like. Most of the time, they’re in what’s called the M2 anti-inflammatory mood. What that means, these little guys pick up dirt, debris, Recycle them. Turns on an enzyme called interleukin-10 that’s anti-inflammatory. And just kind of does general housekeeping. And just kind of does general housekeeping. However, when a trigger comes along. However, when a trigger comes along. They… it’s the same glial cell, but it moves over to a very pro-inflammatory enzyme. A pro-inflammatory glial cell. And it triggers these 3 enzymes, Actually, these four. That are pro-inflammatory. Tumor necrosis vector alpha, Interleukin-6. NF Kappa B, Inos. Now, these create inflammation. So you might think, well, why is that good? Well, if you have some foreign invader, virus, bacteria coming in, parasite. If you didn’t have these guys coming to the rescue, you would just die of infection. So, these guys are your friend unless they’re your worst enemy. Because TNFA, and we’ll show you when we actually do a demo account, TNFA can be overactive. So, in other words, it over-responds. Interleukin-6 can be overactive. And if Kappa-B can be overactive. The INOS, and I’ll explain each of these as we go through a demo, can be overactive. Now, what that means is, you’re very good at killing virus and bacteria. But this is where autoimmune disease comes in, and just inflammatory conditions. Now, this is just speculation, but we think what happened is, as you know. Thousands of years ago, we didn’t have refrigeration, we didn’t have sewer, we didn’t have pure water, and we didn’t have antibiotics. So, if you made it to 40, you were an old-timer, because everybody was dying of infection. So, what we believe happened is, by what’s called natural selection, Having these overactive. A thousand years ago was to your advantage. Dr. Deb Muth 00:22:31 Hmm. Bob Miller 00:22:32 But now… We have pure water, we have refrigeration, we have sewers, we have antibiotics. But now we have environmental factors that are stimulating them. Now it’s to our disadvantage. And we’ll talk about that a little bit as it relates to the hemochromatosis genes and maybe the G6PD. Dr. Deb Muth 00:22:48 Yep. Bob Miller 00:22:49 Now, why are we becoming so inflamed? Let’s look at the triggers. Now, one of my, favorite expressions is. I was born all the way back in 1954. Dr. Deb Muth 00:23:01 And it was a different world back then. Bob Miller 00:23:05 These are some of the triggers. And we’ll get into these, but right now, high fructose corn syrup, And the high-fat diet. High fructose corn syrup only came about in 1968. So now we’re being exposed to high fructose corn syrup. Then… we didn’t have these, these viruses like COVID. Dr. Deb Muth 00:23:26 Yeah. Bob Miller 00:23:27 Now, there’s now pretty strong evidence that COVID Was actually, you know, made as a gain of function. It’s debated, and I’m not taking an opinion on it, but there’s some people who believe Lyme disease was also a part of experimentation. Dr. Deb Muth 00:23:40 Go. Bob Miller 00:23:41 Then we have molds, and it appears as though mold is getting stronger. you know, 20 years ago, when I was seeing folks, mold wasn’t on the radar. I would say 7 out of the 10 folks we speak to today have mold problems. Yeah, 20 years ago, we talked more about mold allergy being an issue versus mold toxicity being an issue. Right. So… I know some folks are, you know, speculating what’s happening, but one of the theories out there is that EMF is strengthening mold. I don’t know if you ever heard that theory, and I don’t… Dr. Deb Muth 00:24:13 I have. Bob Miller 00:24:14 I’m not claiming it’s true, but it’s an interesting theory. Then even, you know, your black mold from water-damaged buildings. Then our air pollution is getting worse. We’re getting more toxic metals. Dr. Deb Muth 00:24:26 You know, if we have a… Bob Miller 00:24:27 You know, we’re gonna look back someday and say, what were we thinking, smearing aluminum into our armpits? The, what were we doing putting mercury in our teeth? Then, you know, glyphosate. When I was a kid, there was no glyphosate. So, all of these herbicides and pesticides. Polychlorinated biphenols, And then EMF. So, we love our cell phones, you know, and I think unless you, or in the middle of the desert, or down in a cave, you’re being exposed to EMF somewhere. So, you know, we have our cell phones with us, we have, We have Wi-Fi, the towers are everywhere. And we don’t know long-term, but we may find that this can… this creates some inflammation. And I don’t know if you get any folks, but do you have any folks that have… are they EMF sensitive? Dr. Deb Muth 00:25:16 Oh yeah, we have a whole bunch of them. Bob Miller 00:25:18 Yeah, and then if you have any TBIs, So, plenty of things here. that will stimulate into the microglia, M1. Now, you could say, well. We’re all pretty much exposed to the same thing. Why do some people get hit harder than others? So here’s where we’re gonna start. There’s an enzyme called Nrf2 and RF2. And Nrf2 is the enzyme that senses when there’s inflammation. And turns on hundreds of anti-inflammatory enzymes. We’ll show when we do the demo, you can have genetic weakness on NERF2. And NERF2 inhibits and slows down microglia M1. supports M2. Now, if it’s not complicated enough, there’s an enzyme called KEEP1. And KEEP1 inhibits NRF2. And you can actually have gain of function on keep 1, that makes Keap 1 stronger. So… A lot of the people who land on my doorstep So… A lot of the people who land on my doorstep Both parents gave a mutation on KEEP1, making it overactive. Both parents gave a mutation on KEEP1, making it overactive. Dr. Deb Muth 00:26:31 Hmm. Dr. Deb Muth 00:26:31 Hmm. Bob Miller 00:26:32 Suppressing Nrf2, nerve 2 might be weak. So, nobody’s putting the brakes on, M1. And by the same token, Nerve 2 supports M2. Then there’s a process called mTOR and autophagy. mTOR stands for mammalian tard of rapamycin, the growth of new cells. And then autophagy, taking our dead cells and recycling them. We need a balance between the two of them. If we didn’t have mTOR, the sperm and the egg would never become the baby, the baby would never become the adult, we wouldn’t make new cells. But our cells are constantly, you know, the old cells dying off. Autophagy is where we take that debris from the cell and recycle it, just like a farmer Plows the crop under at the end of the year. The dead plant then becomes the fuel for the spring, your dead cell becomes the fuel for the spring, and that’s autophagy. So we’re gonna look back someday and say, what were we thinking? We give our animals growth hormones so they get fatter faster. Oh my. So, we consume those animals, and inventory runs faster. Now, for anybody who’s, You know, maybe above 40, 45 years old. Think back when you were 12, and what did girls look like? They were primarily flat-chested little girls. Now they look like 16-year-olds. Because environmentally, we’re jacking up mTOR. So, mTOR stimulates microglia M1, suppresses microglia M2. Probably 80% of the folks we visit with. This is the part of the problem. NRF2 is weak. mTOR is strong. Environmental factors come along. And this guy gets carried away. He doesn’t do that burst and move back. Stays here. We’re calling that How environmental factors create a locked-in, pro-inflammatory. and neurotoxic phenotype. In other words, once it starts, it just keeps… Feeding upon itself. Alright, so what happens now when microglia is overactive. it triggers these 3 enzymes, TNFA, N of kappa B, And interleukin-6. Each one of these can have genetics that make them run stronger. Then it stimulates an enzyme called NLRP3, Which makes what are called inflammasomes. Now, guess what inflammasomes can be? Your best friend or your worst enemy? Because they will, if you’ve got, again, a virus or bacteria, or possibly even some bad cells in the body. They will zap them. Well, that’s good. Unless it’s overactive. Unless it’s overactive. And then what it does, through interleukin-1 beta, makes excess glutamate. And then what it does, through interleukin-1 beta, makes excess glutamate. Anxiety, gut inflammation, OCD, ADD, autism. And, you know, glutamate, we’ll talk about that a little bit, but glutamate makes you intelligent, highly motivated go-getter. but can also be excitatory. And then, look what it does. Let’s see, do I have the drawing tool here? Yes, I do. Okay. So, it comes down through here, Makes the glutamate. Comes back up through here. through the ADORA 2A enzyme, Then we’ve got a feedback loop that feeds upon itself. Then, through interleukin-18, we make histamine. and mast cells. And then through histamine receptor site number 1, we come back and spin it. And now you’ve just got this spinning feedback loop. So, the glutamate will make you anxious, the histamine will give you allergies and make you anxious. And you’re allergic to everything, and you’re feeling horrible. Now, it doesn’t end there, Dr. Dad. It then goes on to make something called gast dermins that creates pyroptosis, where it actually starts punching a hole in the cell membrane. And you’re only going to be as healthy as your cells are. Just a little background. You know, we’re made up of trillions of cells, and each one of them has what’s called a lipid bilayer, made from lipids, which comes from fats. And you’re only going to be as healthy as those membranes are. So that’s why we coined an interesting phrase. Cellular CPR. Construct the cell. Protect the cell. And restore the cell membrane. And we believe that’s going to be revolutionary in the functional medicine world. So… It’s not hard to figure out that if you start punching holes in the cell membrane, that’s not a good thing, okay? Bob Miller 00:31:22 Now… There’s an interesting molecule called NAD. Thicotide adenoside dinucleotide. And anybody who’s in the, you know, listening to the health podcasts and things, they’re… They’re, they’re learning about NAD. And I’m going to show you a chart later, all the good things that NAD does, but For the most part, it helps what’s called sirtuins. And sirtuins are quite interesting. If anybody’s looking at longevity. The sirtuins is where they’re looking at.Because sirtuins turn on good things. Turn off bad things. And I’ll show some charts on that later. So for right here, this sirtuin uses NAD, to slow down NF-kappa-B. CERT 2 uses NAD to slow down an ORP3. So, if we’ve got genetic weakness on these, or we don’t have enough NAD, We don’t hold this pathway back. Make sense? Dr. Deb Muth 00:32:24 Yeah, makes perfect sense. Bob Miller 00:32:25 Now, I’ll show this a little bit later. So, people are like, oh, well, I’m gonna start taking some NAD. Dr. Deb Muth 00:32:31 Right. Bob Miller 00:32:32 And there’s functional doctors who give NAD intravenous. It was just this morning, I was talking to a woman who said, Oh my gosh. I went and got intravenous NAD, and it took me a month to recover from that. Dr. Deb Muth 00:32:45 Hmm. Bob Miller 00:32:46 what happens is, and I’ll show this in a little more detail, there’s an enzyme called CD38, that’s stimulated by NF-kappa-B. And it takes NAD, To make intracellular calcium. that stimulates NLRP3 and actually makes things worse. So, if we have this guy upregulated, and I’ll show a chart what does that. taking NAD will make you worse. Again, when I go into the software, I’ll show you that whole pathway, so… I would encourage people, you know, just don’t go out and start taking massive amounts of NAD, you know, stick your toe in the water, see how you do. Because everything you’ve heard about, how good it is, is true, unless this guy says, oh, thank you very much, let me make more inflammation. Now, this might be part of our innate immune system, that if we have some pathogen that’s gonna kill us. By golly, we want that to happen. But if this is happening by environmental factors, Then it’s detrimental. So the immune system that protected us a thousand years ago now might be turning on us because of the environmental factors that we showed earlier. All right. Then there’s an enzyme called PARP that’s NAD-dependent, and that actually repairs strain breaks in your DNA. Now, the next thing that happens… is there’s an enzyme called NADPH oxidase that gets stimulated. and something called INOS. Now, I’m sure most people know about nitric oxide. It’s a gas that dilates your blood vessels. That’s why sometimes they’ll even give people drugs, nitroglycerin, to boost their nitric oxide. That’s why people are doing beetroots and other things to boost their nitric oxide. But there’s an OS3 enzyme that makes the nitric oxide that’s good for blood flow. But there’s an INOS That makes nitric oxide to kill pathogens. probably might be the third or fourth time I’ve said this. That’s a good thing, unless it isn’t. So, if it’s killing some pathogen, great. It was just misfiring. it combines… With superoxide that’s made by this enzyme, and makes something called peroxynitrite, which is one nasty free radical that chews you up and spits you out. So, the NOx enzyme, NADPH oxidase, uses NADPH, To make this free radical called superoxide. If we have time, we’ll get into it. NADPH is what your body needs to recycle your antioxidants.So, I coined the phrase, the NADPH steel. Where the NOX enzyme takes this very important NADPH, And rather than being useful, makes superoxide. Now, again, is that fine if you’ve got some bacteria to kill? Of course. But if it’s just chronically running, it’s just making all this chronic inflammation. Then it makes something called hydrogen peroxide. And we need to clear hydrogen peroxide by 3 enzymes, catalase, thyroid reduction. And glutathione peroxidase. If we have genetic issues on here, or we don’t have the cofactors. There’s something called the Fenton reaction, discovered in 1895 by Dr. Fenton. Where hydrogen peroxide combines with iron to make what are called hydroxyl radicals. And guess what they do? They create lipid peroxides, That damages your cell membranes. Now, again, the body’s pretty darn amazing. We have glutathione, And here’s where your body’s taking glutathione and recycling it. But look who’s needed to recycle it. NADPH. So, if this guy up here is chewing it up, We don’t recycle our glutathione. And then an enzyme called glufon peroxidase 4, Takes this damaged lipid and repairs it. So, here we’ve got this protecting, we want to protect it by not having this happen. But then we also need this guy to do the restoration. So, there’s a lot that can go wrong in here, Dr. Deb. Dr. Deb Muth 00:37:07 There’s a lot that could go wrong. And I can imagine some of my listeners are thinking that lipid peroxidase, is that the same thing as what they’re thinking of when we talk about lipids and cholesterol? Is that the same process that’s happening there? Bob Miller 00:37:22 Well, no, no, the lipids can be used to make cholesterol, but here we’re talking about where they’re going to build the cell membrane. And they’re being… and they’re being, destroyed. If anybody would like to see a visual representation of this, just go on YouTube. And type in, ferrooptosis Animation. cool little video, it’s about 3 minutes long, and it shows the lipids coming over, being oxidized, and now GPX4 fixes them, so… YouTube, Pharaoptosis Animation, cute little video. It’s just that really… Shows vividly what we’re… what we’re talking about here. Now, this is… Dr. Deb Muth 00:37:59 And so this is very common, too. Like, a lot of people do hydrogen peroxide IVs. Dr. Deb Muth 00:38:04 And so, if somebody doesn’t know their genetics, they could have a problem with doing those, just like they could doing the NADHIVs, correct? Bob Miller 00:38:13 Sure, yeah, yeah, yeah. So, I’ve talked to so many, you know, of course, the hydrogen peroxide kills pathogens. I mean, that’s what it does. So… but I’ve spoken to so many people that said. I had one client that said they’ve never been the same after having one hydrogen peroxide infusion. Dr. Deb Muth 00:38:30 Interesting. Bob Miller 00:38:31 Yeah. So… it can be… I see why people use it, because it. Bob Miller 00:38:36 pathogens, But on the other hand. And now’s a good time to speak about… I don’t have it on here, but there’s a, there’s an enzyme called the HFE gene. And that is what causes you to absorb iron. And there’s mutations in it that cause something called hemochromatosis. Were you overabsorb iron? Now, true hemochromatosis is when both parents give you a mutation. But there’s now growing evidence even a heterozygous can cause a little bit more iron absorption, not to the human chromatosis point, but overabsorption. So, if you overabsorb iron, And you have too much hydrogen peroxide that’s not cleared, All kinds of inflammation. Now, what’s happened is sometimes this inflammation Will damage the red blood cells. And some well-meaning doctor says, oh, you need some iron. And they take iron and it makes it worse. So, can’t tell you how many people I’ve said, you’ve got the overabsorption of iron, and they say, well, that can’t be right, because I’m low in iron. Well, that could be because it’s being chewed up here. Dr. Deb Muth 00:39:40 Sure. GPX1 and TXN turn it into, to water. The, catalase turns it into water and oxygen. Dr. Deb Muth 00:39:58 Now, I see a lot of my clients who have mutations or SNPs on that GPX gene, on that glutathione gene. And they really struggle to clear a lot of their toxins. Bob Miller 00:40:12 Sure. Dr. Deb Muth 00:40:14 Yeah, absolutely. Well, GPX4. Bob Miller 00:40:18 is what, repairs, but you can see GPX1 Is what uses glutathione. To turn hydrogen peroxide. So, but it all depends upon having enough glutathione. Dr. Deb Muth 00:40:30 Yeah. Bob Miller 00:40:31 Well, guess who controls making a glutathione? Dr. Deb Muth 00:40:34 Nerf 2. Bob Miller 00:40:37 So, if you have a keep one weakness, or strength to two… I’m sorry, keep one is too strong. Nrf2 is too weak. You don’t make glutathione. So, when a lot of people do that, it’s like, well, I’m gonna take glutathione. Dr. Deb Muth 00:40:51 Right. Bob Miller 00:40:52 And some do great, and some do poorly. You know, because… and I’ll show this on one of the other charts. You can see here that the, The glutathione has to be recycled. And if we don’t recycle it, it actually turns into superoxide free radical. So… NADPH are the cofactors, For taking the oxidi… here’s oxidized glutathione, here’s reduced. So, this is a good glutathione. After it does its job, you can see it becomes oxidized.We need to recycle it. Well, if we have weakness on the enzyme that does that, or a weakness in Nrf2, or not enough NADPH. The oxidized glutathione never gets recycled. So, I’ve talked to a lot of people who said, oh, glutathione made me so sick, and say, well. Dr. Deb Muth 00:41:43 Yeah. Bob Miller 00:41:44 You need it, but you need to recycle it. Dr. Deb Muth 00:41:46 Can you speak for just a brief moment, too, about MTHFR? That is a very popular gene, it’s all over social media as the major gene, but can you speak to a little bit about that, and how that fits into this whole process of things? Because it is just such a small piece. Dr. Deb Muth 00:42:04 understanding genetics. Bob Miller 00:42:06 Yeah, to be honest, it drives me nuts. Dr. Deb Muth 00:42:08 Me too. Bob Miller 00:42:11 Alright, so… You know, there are people on social media I won’t say what I think, I’ll be kind. But… But the, And, you know, they might mean well. But they talk about, if you have MTHFR and COMT and PEMT, that’s… oh my goodness, that’s horrible, and we’ll fix that for you, and you’ll be fine. Bob Miller 00:42:36 it just irritates me to no end. And it really could get anybody who’s doing this legitimately in trouble. I mean, I’m afraid someday, you know, there might be some cracking down on this kind of nonsense. Now, to answer your question about MTHFR. Dr. Deb Muth 00:42:51 I mean, it really is, but I’ll tell you what, why don’t we hold that thought until I go to another map and I can actually… Okay. Bob Miller 00:42:56 But the real… the cliff notes is the MTHFR puts a methyl group on your folate, which is needed, but it has gotten way, way, way too much attention. And people learn they have MTHFR, and they start taking a multivitamin with methylfolate, then they take a B vitamin with methylfolate. Dr. Deb Muth 00:43:13 And they’re pushing it too hard. Bob Miller 00:43:15 Yeah. So I can’t tell you how many people I’ve helped by saying, stop it. Dr. Deb Muth 00:43:20 Yeah, take less of it. Bob Miller 00:43:21 Take less of it, yeah. So, yeah. Yeah, there’s a… If somebody, say, ranked the enzymes at their level of importance, MTHFR might be 40 or 50 on a scale of 100, you know. Keep one Nerf two. big deals. Dr. Deb Muth 00:43:40 deals. Bob Miller 00:43:41 NQO1 that I didn’t even talk about yet, NQO1, takes your, NA… your NAD goes into NADH, To make electrons for the electron transport chain. you need NQ01 to bring that back. If that’s not working, and I’ll show you on the NAD map how disastrous that can be. Now, the next piece is here, and I think You know, if you talk to any school teachers and say, if you’ve taught for more than 10 years, how are the kids today? Every one of them says, more ADD, ADHD, more autism. Just look at human beings, we’ve never been so agitated. You know, everybody, and it might be a social media thing, but people take a position on something, and if anybody doesn’t share that position, they view them as the enemy. Dr. Deb Muth 00:44:29 And it’s kind of scary what’s happening to us. Bob Miller 00:44:33 So, we can’t agree to disagree anymore. We see anybody who has a differing opinion as the enemy. And, you know, there was… there’s people that didn’t have Christmas dinners together, because they had political differences, like… Dr. Deb Muth 00:44:44 Excuse me. Bob Miller 00:44:45 can’t you put your political differences aside to have Christmas together, you know? Dr. Deb Muth 00:44:49 Right? Bob Miller 00:44:50 become that, you know, no matter what your position is, and I’m not saying anyone’s right or wrong, I’m just saying. You know, in the old days, they used to say that the Republicans and Democrats in Congress would argue policy and then go have dinner together. And now everybody’s all up in arms, angry. Dr. Deb Muth 00:45:05 Yeah. Bob Miller 00:45:06 So… There’s likely multiple reasons for that. But let me show you one of them. That, you know, to what degree this is… very important, we don’t know, but I think We’re beginning to believe this is very important. So, there’s something… there’s a neurotransmitter called GABA. And God buys the don’t worry, relax, be happy. Chill. Okay. Dr. Deb Muth 00:45:31 Nobody has enough of that anymore. Bob Miller 00:45:33 Well, yeah, you’ll be surprised what I’m gonna show you. So, let me see if I can find a, Let me see if I can find the right slide here. Let me look for it here. So, there’s something called a GABA receptor site. And here you can see… This is a neuron, and this is where you, The neuron normally is excitatory. However, there’s normally low chloride in the neuron. Dr. Deb Muth 00:46:09 Hmm. Bob Miller 00:46:10 So, GABA itself is neither relaxing. For excitatory, all GABA does, it opens up what’s called a chloride channel. And then chloride, which has a negative charge, will flow into the neuron. Follow me there? Dr. Deb Muth 00:46:26 Yep. Bob Miller 00:46:27 And as it does, it changes this from a positive charge to a negative charge, And it’s relaxing. and inhibitory. Dr. Deb Muth 00:46:34 Hmm. Bob Miller 00:46:36 Now, on the other hand, there’s enzymes called NKCC1, That will push chloride in. and KCC2 that will bring chlor… oops and bring chloride out. And then there’s a sodium channel. And, sodium has a positive charge. And glutamate will push that in. So, as long as this is happening. And GABA says, receptor sites, open, chloride goes in, Chill. However, If NKCC1 Pushes extra chloride in. KCC2 doesn’t pull it out. and GABA hits the receptor site, the GABA comes flowing out, Sodium comes in, And now it’s excitatory. So Gabba didn’t change. GABA just opened the receptor site, that’s all it does. Dr. Deb Muth 00:47:33 Yeah. Bob Miller 00:47:34 But it’s the chloride balance that’s going to determine whether this is relaxing or not. Now, these are the things that go along with when they lose that KCC2 or gain NKCC1. Pain and sensitivity, burning electrical, neuropathic pain. Normal touch hurts. Sound and light sensitivity. Tinnitus can flare. Headaches and migraines. Seizure tendency. Body jolts. Spasticity, cramps, stiffness, startle reflex. Trouble falling asleep, non-restorative sleep. Anxiety, stress, reactivity, that’s what we have now. Hyperarousal, panic-like surges, irritability, racing thoughts. Brain fog, slowed processing, working memory slip-ups. Mental fatigue. Episodes of racing hearts, sweaty palms, guts on edge. Those are all the things that happen when this GABA switch occurs. Now, here’s what happens, and this is what I’m going to be presenting at an autism conference. When you have a newborn, they need that NKCC dominant to develop. By early childhood, it should… or, sorry, early adulthood. we should move over to the KCC dominant, that’s the taking the chloride out. Nice-looking 25-year-old boys, functioning very well. However, when we get microglia M1 upregulated. Because of environmental toxins, processed foods, Tylenol, aluminum. they stay in NKCC1 dominant, and there’s ADD, ADHD, Autism, the whole spectrum. because… They’ve not moved over to the… They’ve not moved over to the KCC2. And again, this is caused by… Environmental factors. Stimulating the microglia. And then, interleukin-1, interleukin-18 weakens KCC2, interleukin-1 beta, Strengthens NKCC1. high chloride. We open up the chloride channel, In Rebell Excitatory. So, I think when, When the pediatricians get ahold of this, they’re going to be very excited to know that This could be why we’re seeing such a rise, and not just autism, but ADD, ADHD, anxiety, the whole shit mess. Dr. Deb Muth 00:49:58 thing. Bob Miller 00:49:59 Yeah, so… and you can see NF-kappa-B stimulates that. These stimulate it, and I think that’s why everyone’s getting so anxious. Now, there’s a little bit more to it, and we’ll get into this when we look at some of the maps, but… The, the glutamate, Which is excitatory. will stimulate the NMDA receptor, make more glutamate, And glutamate will inhibit KCC2. And then we also need an astrocyte To, take both ammonia And glutamate, and… Turn them back into glutamine. And I’m going to talk to you a little bit about arachidenic acid, and if we have too much arachidenic acid. or TNFA is upregulated, that doesn’t happen. Ammonia goes up, and there may be multiple reasons for this, but this is a reason why some of the autistic kids do flapping. Dr. Deb Muth 00:50:49 Hmm. Bob Miller 00:50:50 Because they’re not clearing their ammonia. And you can tell if somebody has high ammonia by… they get that old person smell, you know. Dr. Deb Muth 00:51:00 Yup. Bob Miller 00:51:01 your vehicle cycle’s not taking out the, the ammonia. Now, last pathway here. There’s growing interest in mast cell activation. So, back here, we talked about peroxynitride. And that will stimulate mast cells, and those are white blood cells that are your best friend, unless they’re your worst enemy. Then it’ll make histamine. And there’s enzymes called histidine decarboxylase that’ll make more. Dr. Deb Muth 00:51:28 I’m sure everybody’s heard of DAO, the enzyme that degrades histamine. Yep. Bob Miller 00:51:31 We can have genetic weakness, we don’t make that. There’s an enzyme called histamine and methyltransferase, That, That breaks down the histamine. Then if we don’t do that, it’ll get stuck in the histamine receptor site. And then it’ll make something called, renin. Which will cause angiotensinogen to turn into angiotensin. One, that turns into angiotensin II,And that’s where people make aldosterone, where they’ll get the, The swollen ankles and high blood pressure. But interestingly, there’s an enzyme called ACE2, that takes this guy and turns it into angiotensin 1-7, Which is anti-inflammatory and also inhibits… TNFA. Now, you can have weakness on ACE2, But… and anybody’s saying, that sounds familiar? Dr. Deb Muth 00:52:25 That’s where COVID comes in, using ACE2. Bob Miller 00:52:28 And now we just found there’s literature that if you get COVID long enough, it can actually make ACE2 not be able to work as well. So look what it does. It comes down here, stimulates the NADPH oxidase, More superoxide. More peroxynitrite. And we’re on a cycle here. We’ve actually named this the Home Cycle Hypothesis, the proposed feed-forward loop. That just keeps feeding on itself. All being caused by… Primarily, The environmental factors. But hitting those who have genetic weakness the hardest. That’s why. Dr. Deb Muth 00:53:08 To the people. Bob Miller 00:53:09 Don’t live in a moldy house. One person is sick as can be, and the other person says, well, you must be imagining things, because I don’t feel anything. Dr. Deb Muth Yeah. Same thing with long haul, right? Two people can both get sick, one gets sick and never seems to recover, and somebody else gets sick, and they have absolutely no problems with it at all. Bob Miller 00:53:30 Sure. Well, think about it, if you get COVID, and ACE2 is weak, and some of this other stuff is going on. This thing just starts feeding upon itself. Dr. Deb Muth 00:53:38 Keep creating more inflammation, more complications, nothing’s calming down. Bob Miller 00:53:43 Yeah. Now, you, you ask about, MTHFR. So, this is the, this is the, the software called Functional Genomic Analysis. There’s a demo report we have. So, let’s talk a little bit about, MTHFR. So, we actually have a map called a methylation map. Now, what happens is, when you do your saliva test, you, you know, you spit, you put some saliva. in a collection kit, goes to a lab, takes out the DNA data, sends it to the computer, and now you can actually see it visually. Okay. So, it’s gonna take a second for this, data to load up, it’s, and each of these Circles, each of these ovals, is an enzyme. And the data gets loaded up to see where it is. So, until it gets loaded up here, I didn’t preload this. There it goes. So… The primary thing about methylation is There’s a nasty substance called homocysteine that, if it’s too high, can really be detrimental. The body takes methylfolate, and combines with methyl B12, To bring this back up to methionine. And then through the MAT genes, we make SAMI, S-adml methionine. Which is involved in so many processes. Then after it does its thing, it turns back into homocysteine. And this thing needs to keep spinning around. That’s why, you know, it’s a good idea to keep homocysteine at, do you have a number that you’d like? 7, 8? What do you like for a number? Dr. Deb Muth 00:55:24 Yeah, I like mine below 7. Bob Miller 00:55:26 Yeah. So if the homocysteine goes too high. It, caused all kinds of problems. So, here’s where you ask about the MTHFR. So, here you can see on this individual. I click on MTHFR, and you can see it comes up here, here’s the C677. And you can see here where it says, variants. I’ll… I’ll draw in case somebody’s having a hard time seeing that. So, you can see there’s nothing in there. That means there’s no genetic mutations. If one parent would have given a mutation, there’d be a 1. If both parents did, there’d be a 2. Now, here’s why Yes, methylation is important, I’m not saying it isn’t important, but look at this MTHFRC677. In my software. Only 42.5% of the population does not have a mutation. 44.7% have won. 12.9 have 2. So, this isn’t some rare, oh my god, I’m gonna die… Kind of thing, yeah. Dr. Deb Muth 00:56:27 Right. Bob Miller 00:56:28 So, And then what happens is that, and again, I’m not dismissing methylation, I… we could do a whole show on methylation. Bob Miller 00:56:36 get it. But I think that what people are doing is they’re, they’re learning about MTHFR, they get it measured, they panic. They start taking massive amounts of methylfolate, which many times is to their detriment. Dr. Deb Muth 00:56:50 Well, it’s… and isn’t it true, too, with MTHFR, like, you have to also look at MTR, MTRR, and the more we stack up of those, the more complicated than MTHFR can be. It’s not… it’s not as simple as just saying MTHFR 677 versus 1298. It’s more complex than that, kind of like what you’ve already shown with some of the other things. There’s more to it than just that one little sliver. Bob Miller 00:57:17 Oh, sure, well, let’s take a look. So, remember I said there’s a cofactor? One of the cofactors is called FAD. Just a Bob Miller observation, that’s all. But when people have trouble with their riboflavin and they don’t have enough FAD, They’re doing much worse than people who have just a C677. So, right here, you could have perfect C677th. And if you don’t have the cofactor, it’s not gonna work, okay? Dr. Deb Muth 00:57:48 And as you said, there’s an MTR enzyme. Bob Miller 00:57:51 that takes methylfolate and methyl B12, to spin it around. So, here on this individual. here’s your… here’s your B vitamins, or I’m sorry, your B12s. There’s an enzyme called TCN1 that takes it from the stomach into the blood. Then there’s other enzymes that take it from the blood into the tissue. And if you’re having trouble here. Well, then you’re not going to have this working, so… Even if you don’t have MTHFR, And you have MTR, like this, no, I’m sorry, this person doesn’t. But they have the MTRR, and then they don’t have enough B12, this isn’t gonna work, aside from that. And then there’s a middle pathway. And then there’s enzymes called the MAT1. they take the methionine to the salmon. If that’s not working, we stick… we get stuck in methionine. So, it’s, it’s not just an MTHFR. And then, one of the things that people forget about. is through these CBS enzymes and CTH, We make cysteine, which is needed to make glutathione. The master antioxidant. So, it really is that… I call it the, The 3D chess game played underwater. Dr. Deb Muth 00:59:07 It really is. I mean, I see people who have CVS, COMT, glutathione, MGHFR genes. And some of them function just fine. Like, they have Like, I look at this person and I’m like, oh my gosh, I don’t know how they’re functioning because they’re double mutated on so many pathways, but yet they don’t have a lot of symptoms, they don’t have a lot of complications. Somehow their body has figured out a way to adapt to what it has so it can stay alive and it can function at a high functioning level. Bob Miller 00:59:36 Yeah, and they may be, you know, eating right? Yeah. Staying out of a moldy house. reducing stress. So, it’s diet, it’s stress, it’s genetics, environmental factors. So, yeah, we can’t just say somebody’s gonna be good or somebody’s gonna be bad. You know, some people get scared, oh, I got all these, it’s like, well… Bob Miller 00:59:56 Are you living in a moldy house? You know, and if you live in a moldy house and your glucuronidation pathway doesn’t do well, or if you’re, you know, a smoker, or you’re constantly eating junk food, I mean, all. Bob Miller 01:00:07 things come together. Although, you know, when we focus on genetics, we’re well aware that this is just a piece of it. You know, you could have identical twins, Genetically, and if one… Is exposed to mold and smokes and drinks and stressed out. They’re gonna be a whole lot sicker than their sibling. Bob Miller 01:00:28 Yep. Dr. Deb Muth 01:00:29 Yeah, it’s that concept of taking twins, and one gets raced with one family, and one gets raced with another family, and they don’t have the same… problems that… that each other have, you know? It’s a very unique situation, we don’t think about that enough. Bob Miller 01:00:44 Alright, so again, genetics loads the gun, environment pulls the trigger. So, if you’ve got a loaded gun, but you don’t have the triggers, you’re okay. Dr. Deb Muth 01:00:53 Yeah. Bob Miller 01:00:54 Yeah. So, remember I said I was going to talk about NAD? So, here’s NAD, and what it does, it turns into NADH. And what NADH does, it, Comes down this pathway, what’s called the electron transport chain. And that makes your ATP, that’s your energy. So, if this wasn’t working, we wouldn’t be alive, because we wouldn’t have energy. So it donates an electron, that’s why it’s called electron transport chain. So, we need NAD, To make this, to make the energy. But remember I said that NQ01, this would probably be, like, on my top 10 list of… Bob Miller 01:01:36 Much more important than MTHFR. This one takes NADH back to NAD. If we’re stuck over here, We’re low in this NAD+, But what happens is, NQO1 also provides CoQ10. And CoQ10 Is what’s needed for the electron transport chain to flow. So if we get too many electrons up here. And they don’t turn them into energy. They make a nasty free radical called superoxide. Okay. Now, NAD plus also makes NADPH, And that is needed. Remember I said we need to recycle our antioxidants. So, if we have a problem with FAD from riboflavin. Yeah, we don’t have enough NADPH, Glutathione’s not getting recycled, and you’re gonna be inflamed. And you take glutathione, you’ll feel worse. There’s another enzyme called thimoredoxin. Same thing, needs NADPH and FAD. And same way with your nitric oxide, there’s an enzyme called NOS3, That makes the nitric oxide that dilates your blood vessels. And if we don’t have enough NADPH or fat, You’re gonna make superoxide. Rather than nitric oxide. Now, remember

Who are you when everything you've built your identity on gets taken away?For Dennis Connors, that question wasn't hypothetical. A teenage USA rock climber turned Marine Corps intelligence operator, he served three combat tours in Iraq supporting Tier 1 Special Operations, ran 250 interrogations, and came home with multiple undiagnosed TBIs, severe PTSD, and two strokes — the second partially paralyzed his left side. In March 2018, his call sign was still Villain and he had a plan to end his life the next day. What happened on the other side of that moment took him to the Paris 2024 Paralympic podium as a Silver Medalist and to a TED stage where he made 4,000 people cry.IN THIS EPISODE:Why Dennis stood at the dark edge in March 2018 — and the single moment that stopped himHow undiagnosed TBIs compounded PTSD for years — and why he toughed them both outVulnerability reframed: not disclosing weakness — opening a conversational gateSelf-worth tied to results vs. self-love that doesn't collapse under pressureWhy community with shared passion goes deeper than shared service aloneThe four pillars of perseverance: vulnerability, self-love, disciplined action, communityRELATED EPISODES:Ep. 123 — Bipolar General: Maj. Gen. Gregg Martin's Forever War with Mental IllnessEp. 106 — Transcending Trauma with Dr. Frank AndersonEp. 135 — The Lie of Self-Sufficiency: Jon Macaskill on Why Men Carry Too Much AloneFOLLOW DENNIS CONNORS:Website: dennisconnorsusa.comLinkedIn: Dennis ConnorsGET MORE FROM MTM:Text MTM to 33777 — free weekly newsletterSubscribe & All Episodes: mentalkingmindfulness.comFNT Website: focusnowtraining.comA2A COURSE:12 modules on attention, presence & performance. Self-paced. Built for people who hate the word mindfulness.focusnowtraining.com/a2a→ This conversation maps directly to Module 3 of A2A: Building Unshakeable Self-Awareness Under PressureBRING FNT TO YOUR TEAM:Custom attention, resilience & leadership training. In-person or online.focusnowtraining.com/contactHosted on Ausha. See ausha.co/privacy-policy for more information.

Spencer Jones, Founder of XO Medtech and MedtechVendors.com, shares how frontline nursing experiences led him to patent vascular access innovations and ultimately take devices from idea to FDA clearance and product launch. Spencer walks through learning business fundamentals through accelerators, raising early funding, and building sales and distribution networks, then explains why launching a digital-first, AI-native ecosystem has enabled faster, leaner execution than traditional medtech pathways. Spencer also discusses leadership, clear communication, and why AI adoption is essential to accelerate and de-risk early-stage medtech.  Guest links: https://www.linkedin.com/in/medtech-innovation/ | www.xomedtech.com | https://medtechvendors.com/  Charity supported: Polaris Project Interested in being a guest on the show or have feedback to share? Email us at theleadingdifference@velentium.com.  PRODUCTION CREDITS Host & Editor: Lindsey Dinneen Producer: Velentium Medical   EPISODE TRANSCRIPT Episode 080 - Spencer Jones [00:00:00] Lindsey Dinneen: Hi, I'm Lindsey and I'm talking with MedTech industry leaders on how they change lives for a better world. [00:00:09] Diane Bouis: The inventions and technologies are fascinating and so are the people who work with them. [00:00:15] Frank Jaskulke: There was a period of time where I realized, fundamentally, my job was to go hang out with really smart people that are saving lives and then do work that would help them save more lives. [00:00:28] Diane Bouis: I got into the business to save lives and it is incredibly motivating to work with people who are in that same business, saving or improving lives. [00:00:38] Duane Mancini: What better industry than where I get to wake up every day and just save people's lives. [00:00:42] Lindsey Dinneen: These are extraordinary people doing extraordinary work, and this is The Leading Difference. Hello, and welcome back to another episode of The Leading Difference podcast. I'm your host Lindsey, and today I'm delighted to welcome to the show Spencer Jones. Spencer is the founder at XO Medtech and MedTechvendors.com. He is an RN, MedTech entrepreneur with 12 years of med device leadership. He's a two time med device CEO with 10 plus patents under his belt and has taken devices from idea to FDA clearance and product launch. Spencer has built sales and distribution networks, led product development teams, and raised over 10 million in VC and Angel Capital. Spencer founded XO MedTech in 2024 to create a digital first medtech ecosystem, deploy AI native tools for medtech operators through medtechvendors.com and cultivate the next generation of medtech innovators. All right, Spencer, welcome to the podcast. Thanks for being here. [00:01:43] Spencer Jones: Thank you for having me, Lindsey. I'm very, very excited to be here. Like it's, it's always more fun to be a guest than it is to host the pod, so absolutely thrilled to be a guest on the pod. Thank you for having me. [00:01:54] Lindsey Dinneen: Of course. Absolutely. Well, yeah, let's just, if you won't, don't mind just sharing a little bit about yourself, your background and what led you to medtech. [00:02:04] Spencer Jones: Yeah. Born and raised in Arkansas. I've lived, I traveled a ton and lived in Memphis and whatnot, but grew up in a healthcare household. Dad did anesthesia for, what was it, 36 years or something at the same place. So I thought I was gonna be a CRNA, like actually started pre-med. Took chemistry my freshman year while I was, you know, it was just, I got a C and I was like, maybe, maybe med school's not for me. But but anyways, did the nursing school thing, got out, started working, pretty quickly, knew if you've ever spent any amount of time in frontline healthcare, you just kind of get, it's like a barrage of things that suck. It's just, especially nursing, the devices you're using are commoditized. Like just the workflows are bad. You know, people, it's, healthcare is very broken. Every, it's no secret. Everybody says that. Everybody knows that. So anyways, I noticed pretty quickly that hey, like why isn't this better? Why can't this be like this? And, you know, kind of had that mindset. And before I could even go through like critical care enough to apply to a CRNA school, ended up patenting some devices in the vascular access space. Really leveraged accelerator programs and the entrepreneurial support organizations that were in my area, in my region to, I call it that get that dirt money, which is like the before the seed, you know, your pre kind of, your pre-seed /seed you know, before the pre-seed money. And, and also like the business training, right? Like I wasn't formally trained on business stuff like that. So did that. Did the venture capital hamster wheel a little bit, took a, you know, device through class two de novo clearance. Was doing ride-alongs training, sales reps, doing marketing stuff, you know, managing our ip, managing clinical you know, 300 patient RCT that we had to do in the middle of COVID, launched the product and then past couple years, I left, left that company in 2022. Products still on the market and they got, you know, clearance in, in Europe now and et cetera, et cetera. But just been working more in laparoscopic spine or laparoscopic surgery orthopedic spine and then doing some like consulting projects and, and things like that. And then yeah, XO Medtech and Medtech Vendors that's been. You know, for the past two years, like a big focus. And I know we're gonna talk more about that, but yeah. So it's just been, it's been a great journey. Medtech is one of my --I love it and hate it at the same time, but I wouldn't wanna be doing anything else, frankly. So. [00:04:17] Lindsey Dinneen: Awesome. That's a great intro. Okay. You were, I really, I enjoyed how you sort of went straight from okay, so, so "I, you know, started the career, started in the industry, and then I, I, you know, got a bunch of patents." What were the ideas for the patents? Where did those come from? If we could just go back, how did that, what was that inspiration like? [00:04:39] Spencer Jones: Yeah. So I was night shift, med-surg, big, pretty big hospital in Little Rock. It was like one of the, one of the bigger ones in Little Rock, St. Vincent's, which is like CHI, St. Vincent, et cetera. And like one of my patients --well the, the very first one was a dual lumen peripheral IV. A patient has a peripheral IV in, I need to get a blood draw. They're like, "Go stick his other arm." I'm like, "Why can't we get it out of his, you know, IV that's in his, that's in his forearm?" And, and they were like, "Well, you, you know, you don't want to contaminate, you know, the thing." And I was like, "Oh, okay. That kind of makes sense." And I was like, well, PICC lines have two lumens. So you know, I was like, why couldn't, you know, why couldn't we just have a second lumen on, you know? And I was like, do those exist? And they didn't really exist. There was kind of one that existed, but it was more of like a longer extended dwell peripheral and you know, you kind of needed ultrasound to place it. You didn't really place, you know, normal nurses on the floor weren't gonna place it. And so I kind of, that one was just sheer-- I experienced something that I was like, "Dude, you're kidding me. There's gotta be a better way to do this." You know what I mean? And you know, kind of similar approach in that one. We, you know, that was the very first one so I was like doing these drawings on note cards and then like meeting with a patent attorney and I was like, did that provisional filing and wrote the patent myself and the claims and all this stuff. And the guy thought I was like, just " Okay, yeah, I'll, I'll file the provisional for you, bro, whatever." Filed the provisional, you know, ended up like going to a different attorney 'cause that guy was kind of just not taking me seriously. And so, ended up going to a different person, filed a non-pro provisional, started raising all this money, and that original attorney reached out later, was like, "Oh, so glad, glad to see blah, blah, blah." I was like, "Yeah, yeah, whatever." But then the second one, I, which was Safe Break Vascular, had the, it's kind of similar. Patient was like, had patients pulling out their IVs, pulling out lines, you know, and it's a million things. It's, it's walkie talkie, so like Alzheimer's, dementia, memory care type stuff. You, it's TBIs, it's agitation, sundowners. It's, you're coming off medication, you're drowsy, you forget, you're hooked up. You need to go to the bathroom. You trip on it. The nurse trips on the tubing. There's like a million reasons how, you know. Where mechanical force can get applied to an IV line. And same thing, I was just like, man, like this, it, it feels holding on for dear life is like the wrong approach because skin is only so strong. You get skin tears. Adhesives, you only want them to be so, you know, so, so strong. And it just, you know, it, wrapping it up, then you can't assess the site, you can get infiltration. So it didn't feel like any of the options we had were great. That one, I started to do patent research literally on the floor at the hospital. Like that night. I was like, I, 'cause I knew enough then found someone that had patented it. Like same exact concept. It was a nurse. And design was bad. Like the design, it had springs in it and it was just like not manufacturable and not a good design, but there were like conceptually it was like spot on. And then there were some elements of it that I was like, this would be very useful to have if I was gonna like actually do this. So me and somebody I'd met, and in accelerator program, we bought the patent from 'em for 20 grand which was a steal of a deal. It was like 10K up front, 10K after 18 months. And yeah. And then we turned around and raised a, you know, million dollar seed round within like, within nine months after acquiring the patent, got into an accelerator, ZeroTo510, shout out to them. But acquired the patent in February. Got it, or March, got into ZeroTo510, April. Went there in May, closed our seed round of a million in December, so it was like a nine month, yeah, ordeal. [00:08:03] Lindsey Dinneen: Wow. That's okay. That's awesome. I love the story. I love the fact that it was from boots on the ground going, "Okay, I see this problem. There's gotta be a better solution." That's super cool. So. All right, so you have these patents, you're going and you're working with accelerators. Can you tell us a little bit about what that experience was like, especially since you mentioned, you know, you didn't necessarily have the business background, so there was, there was probably a bit of a learning curve to that whole, you know, how do you get your idea from your, your note card drawing to commercialization. So I'd just love to hear about your experience. [00:08:35] Spencer Jones: Yeah. The, so I did one accelerator before ZeroTo510. It, I basically did two within about a year, a year of each other. It was like back to back to back. But the first one I did, it was industry agnostic. So it was just a lot of like mentorship and lean canvas startup methodology kind of business practice stuff like accounting 101, you know, building financial forecasts and models and like all of that stuff. So I really learned a ton about kind of just non device specific stuff there. Obviously I was learning a ton about device stuff along the way, but then once I got to ZeroTo510, that's when things kind of like really, you know-- and I had, I had won, I won that first accelerator. It was like a competition, and so I had 150K. And I was like, "Oh wow. So maybe, maybe this is gonna be a career path," 'cause I was still working full-time as a nurse and then I got into the second one. ZeroTo510 was amazing. Allan Daisley was running it. James Bell was like the co-director, I think, and it was like bootcamp. It was like, you know, 8:00 AM to 5:00 PM. It was like sessions and mentor hours and office hours and " Alright, we're done with that. You guys work on this for an hour and a half, we're gonna come back and talk about like the finished product and you better have it done." You know what I mean? And it was every day. I lived up at this building. It was amazing sponge mode. You know, it was one of those environments where you're just like constantly soaking it in and learning and learning and like you can feel your brain expanding like every day. You know, you wake up excited. And that one was amazing. Met a ton of people that I still work with today. You know, met my co-founder at XO Medtech. Met him at that accelerator. But yeah, it was just, that one was amazing. I was like, life changing. Came back from that and I was like, "This is what I was meant to do." I felt like I you know, found my calling. And so, yeah, shout out to the people there that you know, we're a part of that. [00:10:20] Lindsey Dinneen: Love it. Excellent. So, okay, so you found your co-founder for XO Medtech, and this is great because I wanted to dive into that. So, so you've, you've now successfully taken like several products to market and of course you have a lot of other great industry experience. What was, how was it different starting XO Medtech and Medtech Vendors than perhaps other things that you'd done in the past? [00:10:47] Spencer Jones: Yeah. You know, I'm gonna say it was way easier just to be honest. I mean, I mean, you know, I think we, we were doing a lot. We started building XO Medtech in 2022, 2023, and at that time a lot of it was like, it was really focused on the community and the training platform and the resources and kind of all the videos and things that we put in there. Which I still like to this day, will stand on it, that like there, if you're an early stage innovator and you're, you wanna like kind of internally like level yourself up, right? There's no better place than like XO Medtech and the training and inside there to do that, right? But, but yeah, it was we started doing it at a time when AI was starting to become, like Chat GBT, what was it, four was coming out or whatever. So we started it kind of before the wave and then as we were continuing to build it in like 2023 which was like the meat of us building it. It was like kind of starting to become more of a thing, but we still weren't really using it that much. But then as we really went into kind of like launch and growth mode in 2024, it was just like a huge tailwind and like being able and, and it continues to be. But like not having to raise, you know, three, four, $5 million to get a business off the ground and to get to a point where you can start selling something is just incredible. I mean, like we are, we are so agile and can move so quickly and, you know, we don't have any investors. We don't want any investors. So like our speed at which we can move is unbelievable. And coming from somewhere where it's " Oh, you wanna put out something for marketing? Route it through the quality management system and like maybe it goes out in two weeks." You know, we can go from like idea to feature in a week. You know what I mean, you know, let alone like idea to like press release, right? That's 10 minutes if we want to be, right? So really it's just, it's a lot easier and this takes nothing away. There's some incredibly rewarding parts of kind of my, like my medtech journey and stuff like that, like the day we got FDA clearance and, and X, Y, and z whatever date, you know, first sale and getting our first GPO contract. But it's, it's definitely more I would say day to day, just like the exhilarating agility, excitement type stuff that you like, don't really get with with me. And I'm not, I'm not taking anything away from, I'm still a medtech person through and through and I'm sure at some at some point I'll you know, do another device. We're developing another device at Lapovations, so, in combo spine. So my hands are still in it, but I love, love, love what we do at XO Medtech. It's so much fun. [00:13:11] Lindsey Dinneen: Awesome. Well, I love hearing that. So tell us a little bit about both XO Medtech and Medtech Vendors and yeah, their, their focuses. [00:13:21] Spencer Jones: Yeah. So I think, you know, like I said, we started XO Medtech and it's, it's a online community. So think like Skool, like S-K-O-O-L School or Circle, or there's some other Mighty Networks, like one of the-- we use Circle-- but you know, it's whether you're ideation or just like curious about medtech all the way through like series A really, you know, we've got, you know, there's community feed, people are posting. I mean, we posted you know, Project Medtech, you know, event stuff, discounts a lot of exclusive stuff where, I think we added, it was like three or $4,000 worth of discounts. Like just for being like once you join XO Medtech. But then there's that primary feed people, it's like a massive exchange of value and it's it's not like LinkedIn. There's no promotion. Like we base, we will take your post down if you're like nakedly promoting your own stuff or your services, whatever. The whole point of it is to be massive exchange of value. So you know, "Hey, we did some like really cool testing, ETO sterilization testing on coil tubing to see how it retained its memory. Here's what we found, your pictures," you know what I mean? Just stuff like that where it's like kind of giving people behind the, behind the curtain peaks at your own organizations or that kind of, those, those moments of alpha, those nuggets that you've found and just sharing it so you can have you know, and they're doing the same and everybody's better for it. But then we have a training course and then some other like mini courses, probably a couple dozen downloadable resources. So these are like, you know, prebuilt, proformas, budget forecasts, you know, IP stuff, due diligence type stuff, like stuff to help you with, get your data room beef, you know, beefed up and looking good. And we do videos. There's some live events every now and then. So, so that was very focused on the founder side, you know what I mean, like the entrepreneur side. We, you know, my co-founder used to run a med device, venture studio, so like doing like business engineering, business development, engineering, you know, kind of market related stuff for like early stage, largely like clinician and inventors and stuff like that. He used to run a, a, a group that did that. And we knew we wanted to kind of start to do more offerings that kind of for that side of the table, like the CDMO contract manufacturer design and development group side of the table. So we launched, we started building MedTechVendors.com and launched it in 2025, February, 2025. And then did kinda a relaunch with adding some like agentic AI features in I think at the end of the summer last year. But it, but at its core, I always say this analogy, it's like Angie's List, right? You know, Angie's List, what do they do? Well, it connects people with local pros. Allows them to like, evaluate, engage them really easily, you know, get, get their stuff done quickly from trusted people. You know what I mean? So we have the same approach. We help device teams, and that could be device teams at large, medium, small, or startup organizations or tech transfer offices, whoever we help those device teams find, evaluate, and engage contract manufacturers, CDMOs testing facilities, design and development groups, one man band engineers, whatever through the platform. We have an an ag agentic AI chat. So like it'll ask you questions about your device. It'll start recommending, "Hey, do you need this? Do you need these types of services? Are you looking for this type of vendor? This type of vendor?" It pre-populates forms. It generates matches for you. You can review each vendor's profile, one click get email intros or request quotes, and we're adding some some really cool additional features around some different like skills that you can run. So, think like a reimbursement skill or market a, you know, different predicate device selection skill, whatever. And so those are all gonna be like linked up to the to this kind of AI agent. I don't wanna say too much 'cause we're still building it. I'm like really excited about, but there's other things that we're adding to it. The ability to do quote, visualization you know, and trying to make it kind of a, you know, a home away from home, a hub where you can track execution, get things done, engage vendors, and kind of evolve it more laterally in kind of the lifecycle journey. Not just " Hey, I'm looking for a vendor," 'cause that's a very acute point in time in a, you know, in a person's journey. But trying to expand it out to say the period of time when you're doing X and Y and Z and looking for a vendor so we can get some really was sticky, more sticky use and add more value. So, that was that. And we've started really focusing on some more like intimate, I would say, engagements with CDMOs contract manufacturers focused on giving their sales and marketing teams massive, massive leverage using AI and ai, AI native tools. [00:17:35] Lindsey Dinneen: Awesome. That's really cool. Yeah. Okay, so going back a little bit to the, to XO Medtech, I know you know you, you mentioned that there's a lot of resources available, but one of the things that I think is super cool, and I would love if you just share a little bit more about this, is you have a course that-- i don't remember the name off the top of my head-- but it's basically sort of Medtech Innovation 101. It's, I think... [00:18:00] Spencer Jones: Yeah, The Playbook. [00:18:00] Lindsey Dinneen: Call it like-- The Playbook! And you call it like the MBA for somebody who needs to learn. So can you just share the value of that and sort of what, what made you go, "Okay. I have, you know, the expertise in all these different areas enough to be able to share the journey from start to finish." [00:18:19] Spencer Jones: Yeah, absolutely. I think like the, the value there partially comes-- I mean, I think speaking about the value, you gotta speak about kind of like why there was a gap there, like how it, why it didn't exist, whatever. There's just a lot of really bad content in medtech. You know, there's a lot of stuff that reads I mean, there's guidance documents, you know, ISO and this and that. Like those are tough reads, right? And then, you know, the, the content around " "here's how you really fundamentally apply these guidance documents and here's how all this fits together." And it just felt like everything was I don't know what the opposite of like inside baseball is, right? Like that kind of " Hey, here's what you really need to know." Whatever the opposite of that is, is how medtech content felt like to me everywhere. It was just like polished press releases, really, like consulting speak. You know, "You gotta be strategic with your analysis." It's okay "You know, you know, you gotta find your champions." "How do I find them? What do I tell them? You know, how do I engage them?" So it was just, that was the big gap. So I think the value, what we tried to do with The Playbook was, you know, give, like I said, pre-seed all the way through Series A, the right information, like the right depth, on the right topics in the right order with the right assets, so resources, downloads, all that stuff along the way so that you can go cradle to grave on this, basically be a novice, or we've had people that have launched products and gone through it and they were like, "Holy crap, I wish I would've had this five years ago." But the whole idea is to basically not make you a supreme expert on any one of those topics. There's 46 different lessons, 47, and like you can get through each one in probably 20 minutes, right, 15 minutes. But not to make you an expert on each individual topic, but to give you like a dangerous level of information on any one, and then make you able to dive deeper on any of them, you know, very quickly and easily. So like when you meet with your, you know, a regulatory consultant or an IP attorney, or go down the list, you are not, they're not saying words you don't know for the most part. You're not paying them $300 an hour or $500 an hour to educate you on definitions and concepts. Right? You're, you're applying principles and evaluating strategy versus " What's that again? Like, how does this, what's the timeline for that?" 'Cause that you know, that's just not good for anybody. You know, so, so that, that's kinda the main, the main value prop thrust of it. And I just, I frankly didn't think it existed, but proof's in the pudding. Like we've sold it to accelerator programs, we've sold it to hospital, you know, innovation departments. We've sold it to incubators, like trade associations that have like their like kind of innovation arms. It works. Like when people do it, it works. It's funny-- we can talk about this too-- but like the, you can lead a horse to water thing. It's funny how many people say they want to be entrepreneurs and say they wanna be innovators and really they just want to just yap. And they don't actually wanna put the time in. I'm telling you, it's like crazy how many, you know, fake entrepreneurs there are out there. But it's okay. It's okay. You know, like there has to be, I think there needs to be some cleaving or weaning or calving of the herd to some degree because we've got, I don't know, and maybe we need to develop 'em more, but it's, it is frustrating seeing it firsthand when it's like "You have a really cool device, but you are so uninvestible and you have no interest in being coachable that it just hurts me." [00:21:30] Lindsey Dinneen: Oh yeah, absolutely. No, I love that you've done that resource and yes, super excited to see hopefully a lot of innovation actually happen and be successful as a result of that. So with, you know, okay, so you have, you have this community now and I'm wondering if there are any moments that kind of stand out to you, maybe as you've built the company, also Medtech Vendors that kind of enforce, "Wow, I am, I am in the right place at the right time." [00:22:00] Spencer Jones: You know, I definitely-- you know, it's, it's, it's really, there's not, I would say, any huge singular moments. I mean, we've had people like get business from coming on the XO Medtech podcast. You know, we've had people meet new clients, new strategic partners type stuff, like in the XO Medtech community. I mean, I've made a ton of friends in the XO Medtech community, people that I talk to you know, every, every week or two you know, Brad Shirley, I'll mention him. He's fantastic. And like I've learned from him, he's learned from me. We've both learned stuff from the community. I, I, I really do think it's though, it's like it's, you know, those-- whether it's a LinkedIn DM or you know, somebody messaging me in XO and they're like, "Hey, I just went through this lesson. It was like, so good. You know, blah, blah, blah." And I think those little things honestly like power me, power me up, give me juice, give me energy. You know, and, and like reading, we, we did a ton of, I mean we probably got 30 people that did kind of like a pre- and post- assessment and they gave their feedback on The Playbook so we could refine it like as we were, you know, after launch and all that stuff 'cause we're constantly trying to improve it. And have reading the testimonials and people just being like, yeah, like "This is, this is killer." People that are brand new, people that have been in the industry for 20 years that went through it. I think so, I think, I think it's kinda like a myriad of those things. I would say some of the stuff on-- and that's on the XO Medtech -- I think some of the stuff on the Medtech Vendor side and what we're doing with, you know, kind of campaigns and the tools that we're developing and the work that we're doing there, like we are fully an AI native organization. Like it, like we, it there is just not at all like a significant amount of people in medtech using AI to like actually do not in their products. I don't care about that. Like I'm talking about like in their day-to-day operations and, and whatnot and like we're trying to change that. And so like in that respect, like we will come out with things, you know, release features, release products, build custom tools for CDMOs and you know, the looks on their faces and like how amazed that they are at X, Y, and Z. And sometimes it's like stuff where it's hey, I'm like building them a just showing them how to do something with not even a tool that we built and like they're blown away. And anyways, all of that stuff, I feel like, man, like this is where I'm supposed to be because like. We, we've gotta make MedTech a more attractive investment opportunity. We've gotta compress the development cycles and the cost to develop and the time to develop and get things to market. You know, and I look at AI drug discovery for the pharma world as like a huge way that that's happening. But we have to have that similar type of like, when you to engage with this, it will be good for our ecosystem and industry as a whole, becoming more investible, becoming more cash efficient and all that stuff because you've seen other sectors, you know, software is taking money from early stage medtech, like nobody's business. You know, people are investing AI and you know, I just looked at the annual report from like HSBC, the Venture Report, and like me, early stage medtech funding continues to be down. You know what I mean? So we just gotta do something like, I, I feel like it's an existential, it's an existential issue for early stage medtech to get better at being scrappy and using AI. [00:25:03] Lindsey Dinneen: And there's so much opportunity there. Yeah, I love that you're helping to promote that. So you've gotten to lead a number of different companies now and through very challenging milestones. And so I'm curious, how has your own leadership philosophy developed over the course of your career so far? [00:25:24] Spencer Jones: Oh, what a good question. You know, I, I hate to say this, but I've almost gotten more cynical, you know. [00:25:30] Lindsey Dinneen: Okay. [00:25:31] Spencer Jones: Well, and it, it's, it's like I try to be very protective of my time and like protective of the time of the people that I work with, right. You know, and that doesn't mean I'm not willing to like go the extra mile and whatnot, but I think it's about respecting people's time. Right? And, and you know, I think honestly my leadership philosophy, I think a lot of it revolves around just like incredibly clear communication and like staying above the fray. No riff-raff, just just executing and moving fast and like keeping expectations really high, because I feel like when you've got complacency, you know, at the top, it just, it like doubles every rung of the ladder lower that you go in the org chart or whatever. You know, so I think like pace, you know, pace and hyper clear communication, like no subversive or passive aggressive or anything. It's just like straight up, like I'll just exactly tell you if I wasn't happy with something or whatever, but I just, I don't know, like I feel, I feel like you know, leadership style too, like I think, I think it, so much of it boils down to communication for me. It's just like really, really clearly communicating and like making sure that people understand what good work looks like and what a, them doing a good job looks like, and where... Yeah, I think, I think being clear about expectations, really clearly communicating those expectations around like work product, what it should look like, how fast it should get done, how many updates I need, or how many questions I expect to get as you're doing this, what resources I expect you to expend and explore before you come to me with something you could Google. Like all of that stuff, but honestly, I, it, it's kind of a tough question thinking in like the more immediate past, just because I feel like there's been such like, almost like a flattening of org charts, frankly, with the way that we're using technology and AI these days where I feel like in the companies I'm operating in right now, like it's mainly just principles and like lower level stuff, like we're either delegating to AI agents or delegating to like VAs that are in a different country or something, you know what I mean? And, and so there's just been a big flattening. You know, seven years ago, six years ago, I was managing, you know, new grads outta college, two or three at a time, and, you know, having to like, have these kind of like, you know, like brotherly, you know, like talks with, you know, these types of things, " Hey, like you really gotta do this" and like coaching and stuff like that, i, you know, there's a, we have to have that stuff. I'm just not in, in organization and honestly, the organizations I'm in right now in startup world I just feel I don't know. Like I, I feel like we're, I haven't seen that and I, I know a lot of organizations that are small and nimble and whatever, and I feel like the org charts are getting real flat in terms of like people that are getting managed, you know, it's a lot of agents getting managed, frankly. [00:28:21] Lindsey Dinneen: Yeah. Yeah, yeah. Interesting. Yeah, that, that's a really interesting insight too. But I really do think that to your point of coaching and mentorship and how much of a difference that makes, but especially, I was just on this conversation earlier today of the critical importance I feel that there is about establishing expectations across the board, whether it's your clients, your employees, your coworkers, just making sure that everybody's on the same page is such a critical aspect of, of setting yourself up for success. So yeah, I love that you touched on that 'cause like I said, literally earlier today. [00:29:00] Spencer Jones: Yeah. And, and can I, can I, quick aside here. It's, it's on topic, but before we move on, I mean, I, I'm not the first person to think this or say this, but I'll, I'll die on this hill. The more you use AI when, when you're using it the right way, right, the better leader and better specifically, the better communicator you'll become, right? Why? So much of interpersonal office drama, bad management, bad leadership is like what we talked about, right? It's poor communication. It's expecting people assumed something or had knowledge they didn't, right? It's not letting them know what you really wanted, what good work looks like, all that stuff. This is all context engineering, right, which is just a similar to prompt engineering, but context engineering is kind of the other more important piece these days with AI. What do I mean by that? Like I'm gonna give a prompt to a chat. Is it in just like a virgin chat or is it in a project? What context, what documents, skills, reference templates, et cetera, access to code bases does that project have, right? What am I telling it to do? How am I breaking that down? How am I, you know, big, high level goal? What do I want it to do? What does the output need to look like? How deep do I want it to go? Right? Like, how many questions I say, "Ask me like five or six questions" when I'm prompting, right, if I want that, right? Give, so giving the other person right in that space to say " What questions do you have?" Right? The, the, the best people at context engineering and leveraging AI in that way end up becoming more, better and better and better communicators because it's-- I mean, yes, you're talking to a machine, but at the same way, like those principles a hundred percent apply to good professional communication. So I'll die on that hill. There's a lot of people that are like brain rott using AI. It's " what's the weather today?" And you know, "how many calories does mayonnaise have?" And those people are not, you know, they're, they're not improving their leadership communication by using app, but the people actually doing it right a hundred percent are, [00:30:52] Lindsey Dinneen: Yes, I could not agree more. I think that is one of the coolest things that AI has taught me personally is-- to your point, to be a better communicator, to be clearer with the way that I communicate, to avoid assumptions that the other person, say, knows what I'm talking about or, or does have the context behind why I asked the question the way I did, or all those kinds of things. So I, I could not agree with you more. Yeah. And it's exciting to see how it continues to evolve. Okay. [00:31:22] Spencer Jones: Yeah. And why, real quick, why, like the AI models, especially with the reasoning models and stuff, Opus 4.6, all this stuff, telling them why they're doing something and why doing it, doing a certain task within that project flow is important is proving to be more effective than telling them how. And I think that's something where, you know, you tell someone what to do, they may do it, but if you tell them and make them believe why it's important, they do it that way, they're really gonna do it that way. [00:31:49] Lindsey Dinneen: Yeah. Love that so much. Okay. All right, so pivoting the conversation a little bit, just for fun. Imagine that you were to be offered a million dollars to teach a masterclass on anything you want, could be within your industry, but doesn't have to be. What would you choose to teach? [00:32:05] Spencer Jones: Does this, assume-- I have a question. Does this assume that I'm already I'm already capable and you know, have enough expertise to actually teach this class? Or is it like I choose this topic, I'm now an expert in that and I get to teach it? [00:32:19] Lindsey Dinneen: I like, I like I like both options, but I'm gonna go with option B because you have a million dollars to play with, right, so you could build up the expertise. Yeah. [00:32:29] Spencer Jones: You know, I would still say like building AI tools, AI agent systems, you know, skills and subagents and these flows and, and really tactically executing that for medtech. And that that goes from founder, you know, innovator to service provider, reg, quality ,reimbursement, like all the way up through sales and marketing and then like CDMO teams, you know, doing contract manufacturing, doing this. Like I, I just, I'm so passionate about it and I, I just see that there's so much untapped opportunity that that is the thing I think, and, and like we, we are doing that not a masterclass, but like we are working with groups to do some of that. But, I just, it's just so, so, so, so much opportunity to do it. And I think there's like weird structural reasons why it's not being adopted the same, you know, at the same clip it is in other industries. But you know, medtech's very rules-based game. You know, you've got your guidance docs, you've got your predicate devices, you've got your clinical trial protocols, you've got your stats analysis. You got your, you know, X, Y, Z hospitals get paid a certain way. Like lots of formulas, lots of reference material, lots of guidance docs. You know, it's very kind of rules and order based system in a lot of ways. And biology has its own kind of, prescriptive way that things happen, right? So I just feel like it's so primed for it. And anyways, I, I just, I wanna see it adopted more so we can see like what's happening with software now, where, you know, the cost to build and, you know, produce and get software to market has com has almost collapsed, but compressed to, you know, from like months, maybe years to, you know, days and weeks and, you know, you got a $200, 250 bucks worth of like software subscriptions, Claude this, that, the other, you can get it done in a week if you, you know, two weeks if you put your mind to [00:34:21] Lindsey Dinneen: Yeah. Yeah. No, that would be an incredible masterclass. I like it. All right. And then how do you wish to be remembered after you leave this world? [00:34:30] Spencer Jones: Oof. God, what a good question, Lindsey. You know, I hope to be remembered at all. [00:34:35] Lindsey Dinneen: Yeah. [00:34:36] Spencer Jones: You know, 'cause I, I'm definitely one of those people that's " nobody cares, nobody's thinking about you." You know, you may have, I, I mean, I think there's like some healthy main character syndrome that people can have that gives 'em confidence, but at the end of the day, no one cares. They're just, everyone's thinking about themselves. But if I am remembered, which I hope to be I wanna be viewed as like someone that was, I'd say, loved their family was a good dad, good husband. I would say brought people joy, was like fun to be around, but like from a interested in other people sense, you know, you know, genuinely cared about people. But I would say that on the professional side, like somebody that you know, would like consistently just delivered an absurd amount of value whether it was, you know, running a business or coaching and developing people at a company or working on behalf of clients or trying to make a positive change. I would say impactful and valuable, you know, with the work that I'm doing. That's, that's, that's how I wanna be remembered. I mean, we don't have big, I don't wanna be a unicorn billion dollar company. No, we have no desire to do that. We don't even have a, a desire to get acquired at any point. We're not raising money, you know, we've, we've deliberately chosen to bootstrap it. You know, we frankly just wanna employ really awesome smart people that we work with, you know, pay everybody well. And like I said, add a absurd amount of value you know, and joy to the people and the clients that we work with and like work at the company with, you know what I mean? [00:36:05] Lindsey Dinneen: Yeah. Yeah, that's a absolutely wonderful legacy to aspire to. I love it. All right. And then final question. What is one thing that makes you smile every time you see or think about it? [00:36:19] Spencer Jones: Oh, I gotta be, I've got a 1-year-old kid. Banks. Banks Austin Jones. So it's gotta be him, and my wife of course. One thing that makes me smile though, every time I see it, oh... you know, I am, I'll cry at a good TikTok, so I'm so I guess that's like a form of smiling, you know? But I'm a pretty big softie, honestly. You know, this is gonna sound weird, but it's kind of those moments where you know, people usually strangers and usually people that don't look like each other, just show humanity to each other. And that could be like holding a door open for somebody. It could be small things, you know what I mean? But I really love seeing those moments and capturing them like candidly, you know? Just you know, oh, I was in a restaurant, I saw this thing happen. You know? I really love that these days. [00:37:09] Lindsey Dinneen: Yeah. Yeah. We all need more of that these days too, so, yeah. Love it. Alright, well, Spencer, this has been a, a fantastic conversation. I really appreciate you and your time today. I love what you're building in the medtech industry and cultivating community and resources and providing value. So just thank you for everything you're doing to change lives for a better world. [00:37:34] Spencer Jones: Thank you. Can I ask you a question? I feel like you were so good, like with the questions and kind coming on the back of like my responses, but I have a question for you like what? You know, what about the medtech space, like most excites you? It can be a specific technology, it can be a specific, you know, company doing something. It can be anything, but what's most exciting to you, kind of looking at 2026 and, you know, kind of in the realm of medtech broadly. [00:38:00] Lindsey Dinneen: Yeah. Oh, I love that question. So I love this industry in general, but there, there's something really special about the energy of being around people who truly care about making a difference. Part of the reason I started The Leading Difference was because I, when I first joined, had sort of noticed this sort stigma from people from the outside who weren't very familiar with the innovation, what it takes to get from, you know, drawing to commercialization. Just didn't, just didn't know. And there was this stigma that people were here just for the money. And then I started meeting all of these incredible change makers who they had personal stories of what they were seeing, or a family member was impacted. And I just loved the fact that there were so many cool people doing such cool things and getting to play a small role in that was the coolest thing in the world. So, you know, I, I say I happily stumbled into medtech five years ago and found my people and my happy place, haven't looked back. I love it. I love being around people who are genuinely trying to do good things in the world. And I hear about new and you know, new ideas every day, and I get excited probably almost equally about most of them because it's just cool to see. So I don't know. Does that answer your question? [00:39:29] Spencer Jones: No, it, it does. I mean, it, it really the, it all comes back to the patient at the end of the day. And I definitely, I, I feel like when people think of like medical device stuff, like their minds immediately go to like Stryker sales reps or something, you know what I'm saying? And there's just so much more to it than that. And there's one of my favorite things about medtech is like the personalities, you know, like you got your wacky, you got your wacky inventors and you know, you got your straight laced regulatory people. But when you get to know 'em, they're, they're absolutely hilarious. You know, you got your attorneys, you got your like, and I, every industry, every industry has their personalities. But I think medtech, you know, you got your beef head sales reps that are like posting " What's up guys? I'm here in the locker room in my scrubs" and like "Motivation Monday." You're like, "Oh my God." But it's just like all these personalities and you go to these conferences and you just see 50 of the same person, but they're each different, they have their own dreams and conflicts and ideas and whatever, but they're still like so in the same box in some ways. I think that's one of the funnier, like funnier things about medtech that just makes it quirky, you know? [00:40:30] Lindsey Dinneen: I love it. And I also love the amount of respect that I see shared amongst people of very, very different backgrounds and areas of expertise. And that was one of the things that made me fall in love with the industry too. I was like, I, for instance, you know, I'm in, I'm in marketing and business development, so I play a very small role in, in sharing about these devices. But people, the engineers that I work with and the consultants that I work with, and everybody in the ecosystem is always just " Wow, well, I can't do what you're doing. And so I think what you're doing is fantastic." And so there's just, there's this mutual respect that I think is super cool about being here too. So yeah, I'm a fan. [00:41:08] Spencer Jones: Yeah, I agree. I agree. We could, we could keep going for, for days... [00:41:12] Lindsey Dinneen: I know. [00:41:13] Spencer Jones: ...On this. I really, I know, I know we have to wrap it, but but yeah. Well, Lindsey, thank you for having me. Seriously, this was a blast. And you know, I'll just maybe like quick sign off plug or something here. If anybody that's listening to this is like interested in, leveraging AI, leveraging AI in medtech or for you personally or whatever, follow me on LinkedIn and post a lot of content about it. You know, talk about it a lot on the podcast. But then if you're, if you're on the founder side, if you're an innovator, like join XO Medtech. If you're on the CDMO side, if you're, you know, on a sales and marketing team, contract manufacturer, CDMO, even like signed development groups, that kind of stuff like, you are like, "We know we need to be using AI to better leverage X, Y, Z, or do this thing. We have all these, we have HubSpot and this thing and that thing, and none of it works together well and we've got too many tools." Whatever. Just hit me up. Let's have a conversation. We're doing some absolutely incredible things leveraging AI, giving these sales and marketing teams like crazy leverage. So yeah, just drop a dm. I'd love to talk to you. [00:42:08] Lindsey Dinneen: Awesome. Sounds good. And we are so honored to be making a donation on your behalf as a thank you for your time today to the Polaris Project, which is a non governmental organization that works to combat and prevent sex and labor trafficking in North America. So thank you for choosing that organization to support, and we wish you continued success as you work to change lives for a better world. Looking forward to seeing the future of all the good things that you're doing. All right. Bye. [00:42:41] Dan Purvis: The Leading Difference is brought to you by Velentium Medical. Velentium Medical is a full service CDMO, serving medtech clients worldwide to securely design, manufacture, and test class two and class three medical devices. Velentium Medical's four units include research and development-- pairing electronic and mechanical design, embedded firmware, mobile app development, and cloud systems with the human factor studies and systems engineering necessary to streamline medical device regulatory approval; contract manufacturing-- building medical products at the prototype, clinical, and commercial levels in the US, as well as in low cost regions in 1345 certified and FDA registered Class VII clean rooms; cybersecurity-- generating the 12 cybersecurity design artifacts required for FDA submission; and automated test systems, assuring that every device produced is exactly the same as the device that was approved. Visit VelentiumMedical.com to explore how we can work together to change lives for a better world.

Some warriors fight battles long after the war ends. On this episode of The ToosDay Crüe, hosts Jake Holland and Stephen LaMonica sit down with US Marine Corps Veteran Hartvig Holmberg V—a retired Master Sergeant whose 24-year career took him from Light Armored Reconnaissance to the elite world of Explosive Ordnance Disposal (EOD). Hartvig joined the Marines in 1997 as a Light Armored Vehicle (LAV) Crewman, serving with the 15th and 13th Marine Expeditionary Units and deploying to Iraq during Operation Iraqi Freedom. Later, he answered another calling. He attended EOD School in Florida, graduating in 2009, and went on to serve with: • Chemical Biological Incident Response Force (CBIRF) • 3rd EOD Company • CLB 26 • MWSS 272 His deployments as an EOD technician included Afghanistan (OEF 13.2) and multiple deployments with the 26th MEU. After retiring in 2021 as a Master Sergeant, Hartvig didn't stop serving. Today he is: • A contract instructor • Part owner of Corvus Training Group V • President of the EOD Motorcycle Club But perhaps his most important mission has been personal. Hartvig openly shares his ongoing healing journey after multiple traumatic brain injuries (TBIs)—learning self-awareness, growth, and recovery through programs like Warrior PATHH and Track Heroes. This is a powerful conversation about combat, brotherhood, identity, trauma, healing, and continuing the mission after service.

20 years. That's how long it took one Marine Corps Veteran - a helicopter mechanic, Iraq War combat Veteran, self-described adventurer - to finally say yes. It took one rec therapist in Cleveland who wouldn't give up on him. This week is his first time at the National Disabled Veterans Winter Sports Clinic. The National Disabled Veterans Winter Sports Clinic is the world leader in rehabilitation. Approximately 400 profoundly disabled Veterans participate from across the country. Veterans with TBIs, spinal cord injuries, visual impairments, amputations, multiple sclerosis, and other severe disabilities are challenged to overcome perceived limitations through adaptive skiing, sled hockey, scuba diving, rock wall climbing, education and other activities. It is the largest rehabilitative event of its kind in the world. Stay tuned all week for more episodes of the Downhill Daily! Learn more: www.wintersportsclinic.org U.S. Department of Veterans Affairs: www.va.gov Proudly supported by DAV: www.dav.org

If you're a veteran, first responder, or law enforcement and you've been feeling off—low energy, no motivation, irritable, or just not yourself—this video explains what's really going on.After years of chronic stress, poor sleep, and repeated exposure to high-intensity environments, your body takes a hit—especially your hormones. Most men are told it's just stress or aging, but the reality is much deeper. From suppressed testosterone to the long-term effects of TBIs and inflammation, this is a problem most doctors—and especially the VA—aren't properly addressing.In this video, we break down why it happens, why traditional treatment often fails, and what proper hormone optimization actually looks like. This isn't about shortcuts—it's about understanding the root cause and fixing it the right way.If you've been struggling and can't figure out why, this could be the missing piece.

Shannon Book grew up in the Kentucky hills, joined the Navy in the mid-1990s and spent 17 years as a Fleet Marine Force corpsman, including two tours in Iraq. He survived Fallujah running on coffee grounds and sheer grit. What nearly broke him came after. When he was medically retired in 2010, the brothers he counted on had moved on, his marriage dissolved, and a years-long battle with alcohol and drugs nearly cost him everything. What kept him going — then and now — is music.On this episode of Tango Alpha Lima, Book opens up about founding the veteran band Vetted, the dark night he pressed a handgun to his own forehead, the DUI that became his turning point, and the Veterans Court system that helped him walk out of that dark alley one step at a time. He's now sober, back in the studio, and sharing the message he once gave others from a stage — this time from a place of hard-earned experience.Also on this episode: why traditional field screenings miss TBIs in combat zones — and the surprising food that became a secret weapon for fighter pilots.Your stories. Your service. Your community. This is Tango Alpha Lima.Show linksLearn more about American Legion Family Day and share how your post is celebrating.Learn more about our guest, Shannon Book.Task & Purpose: TBI field screenings can miss key symptomsLearn more about the Millenium Protocol at TBI Help NowWatch Quiet Explosions documentaryRead "Tales from the Blast Factory"Smithsonian: How a WWII propaganda campaign started the myth about carrots and night vision.

This episode of the DAV Podcast explores the urgent and evolving landscape of military brain health through a partnership between DAV and the Invisible Wounds Foundation. Host Brian Buckwalter is joined by Dr. James Kelly, a leading expert in brain health, to discuss the signature injury of post-9/11 service: traumatic brain injury (TBI) and repetitive blast exposure. The conversation dives into the critical need for objective diagnostic tools—such as bloodborne biomarkers—to replace subjective clinical assessments and move past the myth that a brain injury requires a loss of consciousness. While addressing the specific challenges faced by veterans, including the high rates of undiagnosed TBIs among women who have experienced military sexual trauma, Dr. Kelly emphasizes a message of hope: specialized, personalized treatment programs are already demonstrating long-term, objective improvements for those living with these invisible wounds.

It's Season 12, Episode 18: The Feeling Remains. We have many feelings about Ketch. Is Dean overusing the Colt? How many TBIs did Dean get this episode?Liz investigates whether there is a bunch of world leaders who sacrifice children to an Owl god named Moloch in Bohemian Grove.Research LinksBohemian Grove: The Secret Society Summer CampDaniel Boguslaw Bohemain Grove List.xlsxWhat Really Goes On At Bohemian GroveBohemian Grove - WikipediaSF's Bohemian Club to pay workers $7 million in settlementSan Francisco's secretive Bohemian Grove sued by valetsFormer Cook at Secretive Club in San Francisco Alleges Wage Theft and Break Violations | McCormack Law FirmBohemian Club - Nonprofit Explorer - ProPublicaBohemian Grove - WikipediaMoloch - WikipediaMembership - A Look Inside the Bohemian Grove by Shane KingClogher, Rick - Bohemian Grove - Inside The Secret Retreat of The Power Elite (Mother Jones, Aug. 1981) | PDF | NatureAlex Shoumatoff on the Bohemian Club | Vanity FairJourneys in the Shaw Collection: Bohemian Grove Plays – IlluminationsMoloch | Definition & Facts | BritannicaThe Bohemian Grove Owl: Moloch, Mystery, and the Meaning Behind the Statue - Unsettling ThingsProtests have waned at Bohemian Grove, but suspicion lingers – The Press Democrat[ Removed by moderator ] : r/IAmAThe Bohemian Grove and other retreats; a study in ruling-class cohesiveness : Domhoff, G. William : Free Download, Borrow, and Streaming : Internet ArchiveTHE CULTURE OF THE BOHEMIAN GROVE: THE DRAMATURGY OF POWER on JSTOR

More than 350 U.S. service members have been injured since military action against Iran began in February. The majority of those are traumatic brain injuries. TBIs have become the defining injury of post 9/11 conflicts, and the symptoms can often linger for years, or even a lifetime. Liz Landers discusses more with Jayna Moceri Brooks, who has studied combat-related brain injuries for years. PBS News is supported by - https://www.pbs.org/newshour/about/funders. Hosted on Acast. See acast.com/privacy

A thousand-pound gate falls on a woman. The last thing she remembers is being on the property and going down stairs. She suffers a TBI. The defense's theory: She's a liar. So is her husband. So are the fire personnel who responded. And the bystanders. Sagi Shaked takes host Dan Ambrose through the play-by-play of how he exposed the defense's “conspiracy theory.” The jury saw through it and awarded a $4.5 million verdict. He also breaks down a case where a client stuffed a component TBI after his vehicle was T-boned. Sagi turned a $200,000 offer into an $800,000 verdict. And Sagi previews his TBI masterclass at TLU Beach, where he will explain why plaintiffs' lawyers may be undersettling their cases – and how to avoid it..Train and Connect with the Titans☑️ Sagi Shaked | LinkedIn☑️ Shaked Law | LinkedIn | X | Facebook | Instagram | YouTube☑️ Trial Lawyers University☑️ TLU On Demand Instant access to live lectures, case analysis, and skills training videos☑️ TLU on X | Facebook | Instagram | LinkedIn☑️ Subscribe Apple Podcasts | Spotify | YouTube2026 Programming☑️ Training Witnesses to Transport Themselves and the Jury, April 17-18, Hermos Beach, CA☑️ TLU Trial Skills Training, April 21- 25, Hermosa Beach, CA☑️ Witness Preparation & Direct Examination, May 8 - 9, Hermosa Beach, CA☑️ Dark Arts Trial Craft Bootcamp, May 27 - June 2, Huntington Beach, CA☑️ TLU Beach, June 3-6, Huntington Beach, CAEpisode SnapshotSagi got involved in the Tampa auto case — a T-bone collision with a passenger client — just four months before trial, when the defense's best offer was $200,000.The client had drugs in his system at the time of the crash; the defense argued that the evidence of the drug use should be allowed. Sagi successfully persuaded the judge to exclude it.In the premises case, a 24-foot, thousand-pound gate fell on Sagi's client at an industrial complex. The defense offered $50,000 on the eve of trial and argued that she had simply fallen down the stairs.Sagi used the fire rescue officer's report — written before any lawyer was involved — to get four bystanders' statements admitted as excited utterances, after the officer testified the scene was "frantic" and people were "in shock."In his TBI masterclass at TLU Beach on Friday, June 5, Sagi will cover identifying TBIs, medically managing the case, deposition prep, and trial sequencing.Produced and Powered by LawPods

For young patients with TBIs and their families, challenges persist after hospital discharge.On the podcast, guests discuss how they address barriers associated with this transition. We'll hear perspectives from both sides of that transition: Taryn Townsend at Texas Children's Hospital, and Melaney Grenz, who worked for nearly three decades in the schools and as part of the Oregon TBI team. Grenz joins this conversation from the Center on Brain Injury Research and Training—or CBIRT—which is part of the University of Oregon.Townsend and Grenz discuss how clinicians may engage with schools, the role of brain injury management teams, and common questions from parents.Learn More:How Social Determinants of Health Shape TBI Recovery in ChildrenASHA Voices: Supporting Families of Children With Disorders of ConsciousnessASHA Voices: Overcoming Barriers on Families' Journey From NICU to HomeASHA Practice Portal: Pediatric Traumatic Brain InjuryCBIRT: Return to School

The JournalFeed podcast for the week of Jan 26-20, 2026.These are summaries from just 2 of the 5 articles we cover every week! For access to more, please visit JournalFeed.org for details about becoming a member.Monday's Spoon Feed:The modified Valsalva maneuver is the most effective first-line vagal maneuver for stable supraventricular tachycardia, achieving higher conversion rates and reducing the need for intravenous antiarrhythmics without increasing adverse events.Wednesday's Spoon Feed:Approaches to repeat CT scans in traumatic brain injuries (TBIs) are highly variable. This study recommends a risk-stratified approach based upon injury severity, patients' clinical factors, and timing of initial CT.

In this episode, Vincent A. Lanci shares a deeply personal journey as he announces the release of his new book, "TBI Recovery," which marks the 13th anniversary of his traumatic brain injury (TBI). He reflects on the challenges he faced after being struck by a car, transitioning from a college student to a survivor navigating the complexities of recovery. Vincent emphasizes the importance of awareness surrounding TBIs and aims to provide a roadmap for others facing similar struggles through his book, which combines personal anecdotes, practical strategies, and insights from fellow survivors.Vincent discusses the misconceptions surrounding TBIs and the emotional and cognitive challenges that accompany them. He highlights the significance of community support, both from friends and strangers, and invites listeners to engage with him and share their own experiences. The episode culminates in a heartfelt call to action, encouraging listeners to pre-order TBI RECOVERY for 99 cents and to support one another in their journeys of recovery and resilience. Vincent's passion for helping others shines through as he outlines his vision for the future, including his coaching endeavors and the importance of self-care in the healing process.As You Listen00:00 Introduction and Personal Announcement 01:05 The Journey of Writing 'TBI Recovery 02:51 Understanding Traumatic Brain Injuries 05:11 Community Support and Personal Reflections 09:26 Insights from Fellow TBI Survivors 12:02 Powerful Reviews and Testimonials 15:09 Future Endeavors and Coaching Plans 16:32 Closing Thoughts and Call to Action

Send us a textMorning Prayer (rigtheousness, peace, joy of the Lord; strokes, TBIs, Lupus; salvation) #pray #prayer #morningprayer #joy #peace #righteousness #tbi #lupus #stroke #salvation #healingThank you for listening, our heart's prayer is for you and I to walk daily with Jesus, our joy and peace aimingforjesus.com YouTube Channel https://www.youtube.com/@aimingforjesus5346 Instagram https://www.instagram.com/aiming_for_jesus/ Threads https://www.threads.com/@aiming_for_jesus X https://x.com/AimingForJesus Tik Tok https://www.tiktok.com/@aiming.for.jesus

Guest Introduction:Jennifer Foltz is a practitioner of Biodynamic Craniosacral Therapy, yoga, and compassion-centered coaching. She specializes in supporting people recovering from concussions, traumatic brain injuries (TBIs), and strokes, as well as those dealing with anxiety, depression, chronic pain, migraines, and TMJ. Having walked through her own TBI recovery after a plane crash in 2007, Jennifer deeply understands the importance of slowing down and listening to the body's wisdom. Summary:In this powerful episode, Jennifer Foltz shares her personal journey of recovering from a traumatic brain injury. She opens up about the initial denial and resistance to the diagnosis, the challenging symptoms like rage, emotional dysregulation, and loss of social filters, and how acceptance became a turning point in her healing—even five years post-injury.Bethany and Jennifer explore a wide range of holistic modalities that proved instrumental in Jennifer's recovery, including Biodynamic Craniosacral Therapy, somatic trauma work (like Somatic Experiencing and EMDR), Feldenkrais, light therapy, and the pure joy of dance. Jennifer emphasizes the critical importance of community, highlighting the transformative impact of the Love Your Brain Foundation and her own local Brain Injury Gathering.The conversation delves into the often-overlooked emotional and existential crises that accompany brain injury, offering invaluable advice for both survivors and their loved ones. Jennifer explains the gentle, nervous-system-focused approach of Craniosacral Therapy and how it supports the body's innate healing intelligence. This episode is a beacon of hope, normalizing the long and non-linear recovery journey and underscoring that healing is always possible, connection is vital, and it's never too late to reclaim your life.Jennifer Foltz's Information:Website: jenniferfoltz.comEmail: hello@jenniferfoltz.comHealing Modalities & Therapies Discussed:Biodynamic Craniosacral Therapy: A whole-body therapy that helps release tension patterns and regulate the nervous system by tuning into the body's inherent rhythmshttps://www.craniosacraltherapy.org/Somatic Trauma Therapies:Somatic Experiencing (SE): A body-centered approach to healing trauma and stress.EMDR (Eye Movement Desensitization and Reprocessing): A psychotherapy treatment for trauma.Feldenkrais Method: A movement-based practice that increases awareness and improves function.Light Therapy: Mentioned as part of her therapeutic journey.Support Organizations & Communities:Love Your Brain Foundation: https://www.loveyourbrain.com/ A non-profit offering free, evidence-based yoga, meditation, and community support programs for people affected by TBI and their caregivers.Retreats, Online Groups, & Facilitator Training: Jennifer highly recommends their heart-centered, compassion-focused community.The Brain Injury Gathering (BIG): Jennifer's local, in-person support group in Sebastopol, California, focused on discussion, grounding practices, and mutual support.Key Concepts & Advice:Healing Timeline: Challenging the myth that significant recovery is only possible within the first two years post-injury.Acceptance as a Journey: Emphasizing that acceptance is an ongoing process, not a one-time event.The Importance of Slowing Down: How brain injury forces a beneficial change in life pacing, allowing for deeper awareness.Advice for Caregivers: The critical need for self-care, patience, and maintaining one's own resources to be fully present.Normalizing Symptoms: Understanding that experiences like aphasia, emotional dysregulation, and cognitive changes are common symptoms, not personal failings.Bethany Lewis & The Concussion Coach:Free Guide: "5 Best Ways to Support Your Loved One Dealing with a Concussion" - Download at www.theconcussioncoach.comConcussion Coaching Program: For personalized mentorship in recovery. Sign up for a free consultation HERE Website: www.theconcussioncoach.com

For years now, scientists have shown that daily exposure to bright light therapy, which simulates the intensity of outdoor light, can be beneficial for people with insomnia and other sleep disorders, Seasonal Affective Disorder or other forms of depression. But what if bright light therapy can help people recover from concussions or other traumatic brain injuries? And what if it can also lower the risk of neurodegenerative diseases like Parkinson’s or Alzheimer’s, which people with TBIs are at higher risk for?    Scientists at Oregon Health & Science University were recently awarded a $4 million grant from the U.S. Department of Defense to explore these questions and possibly unlock more secrets about sleep and its effect on health. The OHSU researchers will recruit nearly 120 military veterans who have suffered a TBI. The participants will be given a light box to use at home for one hour each morning for four weeks. Blood samples will be drawn from participants to look for changes in markers that signal inflammation in the brain and changes in oxygen uptake in brain cells.    MRI scans of participants’ brains will also help reveal if the bright light therapy has improved activity of the glymphatic system - a relatively recent discovery about the role of sleep in reducing toxins that can lead to neurodegenerative diseases like Alzheimer’s. Joining us for more details of the study and to share new insights about sleep science is Jonathan Elliott, assistant professor of neurology and co-director of the Sleep & Health Applied Research Program at OHSU.

Marine veteran Tony Crescenzo's life changed in six days after reading an article on quantum physics where he sampled a technology on brainwave entrainment. That discovery led him to create Peak Neuro LLC to help other veterans and first responders transform mental health challenges into resilience. The neuroscience and AI-driven platform harnesses proprietary neuroacoustic technology through a mobile app to enhance sleep, emotional resilience, and trauma recovery. It helps alleviate hypervigilance, PTSD and other effects of TBIs, brain fog, and other issues. Other topics include the infamous Woody Woodpecker, a heartfelt story that inspired the Peanuts comic and the USA 250 Challenge.

Dr. Tom Roselle, DC discusses how injuries, especially traumatic brain injuries (TBIs), can significantly affect hormone production and flow by damaging glands like the pituitary gland and hypothalamus.   This can lead to both immediate and long-term hormonal imbalances, such as adrenal insufficiency, growth hormone deficiency, and problems with thyroid and sex hormones.   These imbalances can manifest as various symptoms, including fatigue, cognitive issues, and mood disturbances.   For all episodes of Ageless Health® with Dr. Tom Roselle, DC please visit: https://www.drtomroselle.com/ageless-health-podcast/   #AgelessHealth @DrTomRoselleDC @WMALDC @RoselleCare #AppliedKinesiology #RoselleCenterForHealing #HolisticHealth #WomensHealth #FertilityAwareness #FunctionalMedicine #HealthEducation #Hormones

Tanika Connesero is a brain injury survivor and health care coach whose personal journey emboldened her to assist family members. Multiple people in her family had TBIs and her mother had a stroke. We all have experienced those life challenges where our children get injured in sporting events or just falling in the shower. Do I need to seek medical advice? Do I just monitor them at home? Tanika, because of her concussions, was in a unique position to identify the TBI signs, navigate through the diagnostic process, and advocate for her family members. Listen in as you hear her share her story, how nutrition plays a critical role in recovery, and why you should never give up because you are a walking miracle.Guest Social Media info - https://www.instagram.com/aloholisticwellness/https://www.facebook.com/AloHolisticWellness Send us a textSupport the showYou can find this episode's transcript here.New episodes drop every other Thursday everywhere you listen to podcasts.

Simply put, Boone Cutler, was one of the most influential veterans of the post 9/11 era. His recent passing comes too soon but reminds us to remember the alarms he sounded for improving VA care and properly addressing mental health. Cutler called out Congress, DoD and VA for overloading vets with prescription meds while holding an outdated stance on cannabis. And he worked to save countless veterans from the suicide epidemic, through The Spartan Pledge. In this episode we hear rare conversations recorded in 2019, where we discussed his life, combat in Sadr City, Psy Op (Psychological Operations) tactics and the gripping origin story of his advocacy. We began at a saloon in Nevada, where Boone shared his family's rich military tradition. Later we heard Boone's miraculous, autobiographical story, recorded at his kitchen table, where we truly got to know the man behind those distinctive black sunglasses. The experiences he shared, would eventually be heard by Congress, and trigger the VA to address the over-prescribing of pills- an issue Cutler dubbed, “The Combat Cocktail”. He powerfully described the pharmaceutical link to the suicide epidemic and illustrated through his own difficult memories, how veterans can consider ending their life. Cutler's story also revealed how he was one of the first vets to reveal the second order effects that stem from TBIs and blast injuries. He further shared fierce advocacy for cannabis, and offered vivid examples of how it effectively replaced the pain killers and heavy psychoactive drugs, which are still prescribed too often today. We finally dove into his love for his wife, family, veteran brothers and sisters, and how The Spartan Pledge, was forged as a battle plan to save veteran lives. There will never be another vet like Boone Cutler. I am honored to have known Boone and called him a friend. Till Valhalla my brother. More on Boone Cutler- his advocacy, and award winning books here: https://boonecutler.com/home/ To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices

In this episode, Dr. Jones sits down with Eric Stoffers, CEO and founder of BioXcellerator, a global leader in stem cell therapy and regenerative medicine. Stoffers is an international pioneer in health, immunity, and longevity, with a vision to make advanced therapies more accessible for patients with autoimmune, orthopedic, neurological, and degenerative conditions.From his work at BioXcellerator to his leadership as Chairman of Solutions for a Healthier World, a nonprofit focused on improving lives through medicine, science, and education, Stoffers brings innovation and compassion to the future of healthcare.Listeners will hear insights on the science behind stem cells, detailing the differences between various sources like adipose tissue, bone marrow, and umbilical cords. They explore the unique properties of mesenchymal stem cells (MSCs), contrasting them with exosomes and addressing common industry myths, including the use of embryonic cells.You'll hear about the conditions showing the most promising results, from orthopedic and autoimmune issues to neurological injuries like TBIs and spinal cord damage. Eric also discusses the regulatory landscape that differentiates treatment in the U.S. from options abroad, the patient experience at his clinic in Medellin, Colombia, and why he believes regenerative medicine is the present, not the future.

Infants and children can experience brain injuries in many ways.What signs can parents keep an eye out for and what can you do to prevent traumatic brain injuries (TBIs)? Tune in to hear Jessica talk about childhood brain injuries with Dr. Sue Wolf, an Educational Psychologist with Empowerment Research. Learn about causes, signs, prevention, and recovery. Host:Jessica Stewart-Gonzalez is the Chief of the Office of Children's Health at the Arizona Department of Health Services. She is married, has two young children, and loves reading (anything except parenting books!) and watching movies and TV.  She enjoys spending time with her kids (when they aren't driving her crazy) and celebrating all of their little, and big, accomplishments. Jessica has been in the field of family and child development for over 20 years, focused on normalizing the hard work of parenting and making it easier to ask the hard questions.Links: Strong Families AZHost: Jessica Stewart-GonzalezGuest: Dr. Sue WolfEmpowerment ResearchEncircle FamiliesBrain Injury Association of ArizonaAZ Department of Education: TBI Training 

In this episode, Lori Tsugawa, author of Let the Samurai Be Your Guide, shares her journey of overcoming traumatic brain injuries (TBIs) by drawing on her Japanese heritage and values. We explore Japanese concepts like bushido (the way of the warrior), ikigai, and ganbaru (never giving up), and discuss how you can apply these principles to your own life.She also talks about her experiences working in a women's prison, shares Japanese folk tales, and highlights her favorite places in Japan. Listen in, and let your inner samurai and otaku lead the way toward healing, resilience, and growth.Connect and Learn MoreWebsite: loriwhaley.comBook: Let the Samurai Be Your GuidePodcast: The Samurai WayLinkedIn: Lori TsugawaResources Mentioned:Attractions: Adachi Museum of Art, Dogo Onsen, Japanese American Museum of Oregon, Kenrokuen, Nagoro Doll Village, Noguchi Museum, Pine Wind Japanese Garden, Ritsurin Garden, Shikoku Mura, SL Yamaguchi, Torrance Art MuseumBooks: Man's Search for MeaningFilms: Fight ClubJapanese folktales: Momotarō, The Mouse's Marriage, The Singing TurtleOrganizations: Albert Camus, Amen Clinics, Ikigai Lab, Kinokuniya, The Ritz Carlton, Toastmasters International, Tuttle PublishingPeople: Ayano Tsukimi, Chiune Sugihara, Daniel Amen, Daniel Inouye, Friedrich Nietzsche, Jean-Paul Sartre, Isamu Noguchi, Sam Ushio, Victor Frankl, Yayoi KusamaPlaces: Hokkaido, Iya Valley, Kochi, Matsue, Matsuyama, Naoshima, Naruto, Portland, Shikoku, Takamatsu, Tokushima, Torrance, Tsuwano

Most personal injury firms treat trials as a last resort. Brett Turnbull built his entire business around it. And made it profitable. In this episode, Brett reveals the marketing and operational systems driving his national trial practice. He breaks down his three-part framework — money, marketing, and operations — and shows how each part works together to attract better cases, prepare his team, and keep the firm financially strong. You'll hear how Brett intentionally builds lawyer and non-lawyer referral networks, why he still invests in paid marketing, and how his intake process uncovers high-value claims like traumatic brain injuries that other firms miss. He also shares how mock trials and focus groups keep his attorneys ready for the few cases that do make it to court. In this conversation, Brett shares: How the “Money–Marketing–Operations” model supports a profitable trial practice The three marketing channels Brett develops for steady, high-quality case flow Why trial readiness is a marketing advantage in PI Systems for spotting overlooked injuries like TBIs at intake Training methods that keep lawyers sharp without risking client outcomes Proven protocols for handling brain injury cases from intake to verdict PIMCON 2025 Tickets On Sale Now. Get yours today! Get Social! Personal Injury Mastermind (PIM) is on Instagram | YouTube | TikTok

Join Jay Gunkelman, QEEGD (the man who has analyzed over 500,000 brain scans), Dr. Mari Swingle (Swingle Clinic), Joy Lunt (RN, BCN, ISNR Past President), John Mekrut (The Balanced Brain), Dr. Andrew Hill (Peak Brain Institute), Joshua Moore (Alternative Behavioral Therapy), Anthony Ramos (Neurofeedback Community Leader), and host Pete Jansons for a special Live Q&A edition of the NeuroNoodle Podcast. Viewers' questions on brain health, Parkinson's, Ozempic, neurofeedback, and mental health are answered.✅ Topic 1 Explained: Jay reveals EEG findings from dissociative identity disorder cases, showing distinct brainwave shifts with personality changes.✅ Topic 2 Deep Dive: The panel examines Parkinson's, CTE in athletes, and how neurofeedback supports progression and medication use.✅ Topic 3 Insights: Exploring Ozempic's effects beyond weight loss, including brain and metabolic impacts.✅ Additional Topics:

In this episode, we break down what veterans need to know about  a VA disability claim for seizure disorders. Whether you're dealing with epilepsy, non-epileptic seizures, or service-connected neurological conditions, understanding how the VA rates seizures is crucial for securing the benefits you deserve.We'll cover the different types of seizure disorders recognized by the VA, how VA rating percentages are determined, what medical evidence may support your claim, and how to handle VA C&P exams for neurological conditions. You'll also learn about secondary service connection and how seizure disorders can be linked to other service-related conditions, including traumatic brain injuries (TBIs).

In this enlightening episode of The Interview Sessions on the Sports Chasers Podcast, we sit down with Nate Pope, Neurological Occupational Therapist and co-founder of NCX Brain Recovery. Nate brings over two decades of experience in treating concussions, TBIs, and post-concussion syndrome using a transformative method called multi-sensory integration therapy.Listeners will discover:How traditional rest-based treatments miss the markReal-world success stories from Nate's clinicHow to spot overlooked symptoms like brain fog, fatigue, or blurry visionWhy athletes of all levels need to take brain health seriouslyLifestyle tips to maintain peak brain function long-term

Coach Hélène on Being Fit Over 50, TBIs, Cold Plunges & the “Win Wall” | Fit Vegan Podcast Ep #392Join our Free Fit Vegan weekly newsletter: https://fit-vegan-coaching.kit.com/newsletterInterested in working with our world class team, Book your application call here: http://book.fitvegancoaching.com/podcastWelcome to the Fit Vegan Podcast! In this episode of the Fit Vegan Podcast, I chat with Coach Hélène about her journey to wellness, from overcoming chronic pain to embracing veganism and cold water swimming. We dive into mindset, self-care, and why resistance training beats cardio for lasting results. Hélène shares how she helps clients break through mental blocks and find what truly works for them—at any age.In This Episode, We Cover: [00:00–12:14] Meet Coach Hélène: Her Inspiring Journey Of Healing, Resilience, And Finding Wellness Later In Life.[12:15–32:03] How Cold Water Swimming Boosts Health, Plus Hélène's Coaching Approach For Real-Life Transformations.[32:04–42:13] Breaking Old Habits, Embracing Self-Care, And Learning Healthier Ways To Cope—At Any Age.[42:14–52:12] A Fresh Look At Our Relationship With Food And Why Strength Training Matters More Than Ever.[52:13–01:03:04] Rethinking Weight And Wellness: What Really Works For Lasting Strength And Energy.[01:03:05–01:12:04] Tailored Fitness For 50+: Competing, Thriving, And Celebrating Personal Wins.[01:12:05–01:30:13] The “Win Wall”: A Simple Tool To Stay Motivated And Proud Of Your Progress.Key Quotes“It's all about consistency!” -Hélène.“ A healthy person has 10,000 problems and a sick person only has one, right?”-Maxime.My name is Maxime Sigouin. I am the founder of Fit Vegan Coaching and Empire Builders Agency. I have a passion for serving and helping people live to their fullest potential.Book Your FREE Consultation Call Here: http://book.fitvegancoaching.com/podcast- Follow me on Instagram: https://www.instagram.com/maximesigouinofficial/- Join our FREE Fit Vegan Community: www.freefitvegancommunity.com- Youtube Channel : https://linktw.in/AyNrSW

In this episode, host Charles Wooley sits down with Beth Hanks-Clark, CNP, of Physical Medicine & Rehabilitation at Arkansas Children's Hospital, for a powerful and personal conversation about pediatric traumatic brain injuries (TBIs)—from severe trauma to mild concussions—and how early intervention and follow-up care are changing outcomes for kids.

Join us on this enlightening episode of "It's a Wrap with Wrap" as host Ron Rapaport dives into the resilient journey of Kelly Tuttle, a neurology nurse practitioner and traumatic brain injury (TBI) survivor. Kelly shares her personal story of surviving a catastrophic car accident, her subsequent struggles, and the path to becoming an advocate for TBI awareness and recovery. Discover the tools and coping strategies that helped Kelly reclaim her life, the importance of recognizing and addressing head injuries, and the ongoing challenges faced by millions living with TBI-related disabilities in the U.S. With her background in neurology and martial arts, Kelly provides a unique perspective on the physical and mental resilience needed to overcome such life-altering events. This episode sheds light on the critical need for awareness, support, and understanding of TBIs, including insights into the healthcare system, the significance of proper diagnosis, and available treatment routes. Tune in to learn more about Kelly's inspiring post-crash journey and her dedication to helping others in similar situations.   Sponsors:    Andrew Matthews, author of "Bouncing Back"                    J. Tucker Miller, author of "The First Four Words"                    Rare Patient Voice-click link for details and to register                    https://rarepatientvoice.com/Itsawrapwithrap                    Hero Soap Company                    https://herosoapcompany.com-Use code RAP for a 10% discount   Links:           kellytuttle.org                     Brain injury of America                     https://itsawrapwithrap.com             

We live in a world that rushes recovery, underestimates the brain, and often labels suffering as stress or burnout. But what if the real cause is a hidden brain injury?

     Join us as we explore the extraordinary journey of Retired Army Lieutenant Colonel PA Stephen M. DeLellis, PA-C, who transitioned from an enlisted soldier to a distinguished physician assistant in military medicine. Starting with his decision to join the Army for college money in the early 1980s, Steve recounts his time in the 1st Ranger Battalion and how influential mentors and pivotal moments shaped his career path. His narrative offers valuable insights into the evolution of military medicine and the significant lessons learned from his experiences, including the Battle of Mogadishu and other key military operations.     Listen in as Steve shares the challenges and triumphs he faced while transitioning from a senior enlisted role to a commissioned officer within the medical community. This episode highlights the evolution of trauma care, particularly advancements in assessing and treating traumatic brain injuries, sparked by the intense combat experiences in Mogadishu. Steve discusses the development of the Assessing and Tracking Tactical Forces (ATAC) program and the collaborative efforts with sports teams and academic institutions to enhance neurocognitive assessment tools tailored for military personnel.     The conversation further explores the impactful work at the Fort Liberty Research Institute and the ongoing partnership between the Geneva Foundation and the Department of Defense. Steve's experiences underscore the importance of effective medical leadership in special operations, emphasizing collaborative decision-making and the evolving role of physician assistants. Whether you're interested in military medicine, leadership, or the innovative approaches to healthcare delivery in challenging environments, this episode offers a compelling glimpse into the world of military medicine and the dedicated professionals who serve within it.   Chapters: (00:04) Military Medicine Journey (08:13) Transitioning to Army Physician Assistant (17:20) Military Transition to Commissioned Officer (30:41) Advancements in Military Traumatic Brain Injuries (36:58) Revolutionizing Traumatic Brain Injury Assessments (41:37) Innovations in Army Medical Research (56:57) Effective Leadership Attributes in Special Operations (01:04:34) Military Medicine Service and Sacrifice   Chapter Summaries: (00:04) Military Medicine Journey Retired Army LTC Stephen M DeLellis, PA-C shares his journey from enlisted soldier to physician assistant in military medicine, highlighting the influence of mentors, Ranger Battalion experiences, and working with special operations units. (08:13) Transitioning to Army Physician Assistant Soldier's journey through special operations, including Panama, Somalia, Haiti, Balkans, and transition to Army Physician Assistant. (17:20) Military Transition to Commissioned Officer Transitioning from 18 Delta course to PA school, realizing gaps in medical knowledge, and challenges of becoming a commissioned officer in the military. (30:41) Advancements in Military Traumatic Brain Injuries JSOC teamwork, advancements in military medicine, TBI program development, and Assessment and Tracking Tactical Forces Initiative. (36:58) Revolutionizing Traumatic Brain Injury Assessments Evolution of TBI assessment tools in military contexts, including ATAC program and research at Fort Bragg. (41:37) Innovations in Army Medical Research Partnership between Geneva Foundation and DoD for warfighter-focused medical research, including ATAC Forces Initiative and Evolution Program. (56:57) Effective Leadership Attributes in Special Operations Effective medical leadership in special operations involves collaborative decision-making and understanding the unique challenges faced by various medical roles, including the evolving role of physician assistants. (01:04:34) Military Medicine Service and Sacrifice Special operations medics rely on telemedicine and virtual reality for complex battlefield care, with emphasis on mentorship and collaboration in the military structure.   Take Home Messages: Career Evolution in Military Medicine: This episode highlights the inspiring journey of transitioning from an enlisted soldier to a prominent role in military medicine. The narrative showcases the unique career pathways available within the military, emphasizing the importance of mentorship and the impact of pivotal career decisions. Impact of Combat Experiences: Through recounting intense combat situations, the episode provides insights into the significant influence of real-world experiences on the evolution of military healthcare practices. These experiences underscore the importance of adapting and advancing medical care in response to the challenges faced on the battlefield. Advancements in Trauma Care: A major focus of the episode is on the advancements in trauma care, particularly in addressing traumatic brain injuries (TBIs). The development of specialized programs and tools for neurocognitive assessment highlights the military's commitment to improving medical responses to combat-related injuries. Collaboration in Military Medical Research: The episode discusses the vital role of partnerships between military institutions and external organizations in advancing medical research. This collaboration fosters innovation and leads to the development of tailored solutions to meet the specific needs of military personnel. Leadership and Innovation in Special Operations Medicine: Emphasizing the critical attributes of effective leadership in military medicine, the episode explores the evolving roles of medical professionals within special operations. It highlights the significance of collaborative decision-making and the growing responsibilities of physician assistants in enhancing healthcare delivery in challenging environments. Episode Keywords: Military medicine, Stephen DeLellis, trauma care, special operations, traumatic brain injury, PA in the military, Fort Liberty Research Institute, Geneva Foundation, Department of Defense, medical leadership, military healthcare evolution, Ranger Battalion, Mogadishu, combat casualty care, Assessing and Tracking Tactical Forces, ATAC program, military innovation, neurocognitive assessment, military podcast, Delta Force Hashtags: #wardocs #military #medicine #podcast #MilMed #MedEd #MilitaryMedicine #CombatMedicine #LeadershipInMedicine #TraumaCare #SpecialOperations #MilitaryInnovation #BrainInjuryAwareness #ArmyHealthcare #PodcastEpisode #MedicalPioneers   Honoring the Legacy and Preserving the History of Military Medicine The WarDocs Mission is to honor the legacy, preserve the oral history, and showcase career opportunities, unique expeditionary experiences, and achievements of Military Medicine. We foster patriotism and pride in Who we are, What we do, and, most importantly, How we serve Our Patients, the DoD, and Our Nation.   Find out more and join Team WarDocs at https://www.wardocspodcast.com/ Check our list of previous guest episodes at https://www.wardocspodcast.com/our-guests Subscribe and Like our Videos on our YouTube Channel: https://www.youtube.com/@wardocspodcast Listen to the “What We Are For” Episode 47. https://bit.ly/3r87Afm   WarDocs- The Military Medicine Podcast is a Non-Profit, Tax-exempt-501(c)(3) Veteran Run Organization run by volunteers. All donations are tax-deductible and go to honoring and preserving the history, experiences, successes, and lessons learned in Military Medicine. A tax receipt will be sent to you. WARDOCS documents the experiences, contributions, and innovations of all military medicine Services, ranks, and Corps who are affectionately called "Docs" as a sign of respect, trust, and confidence on and off the battlefield,demonstrating dedication to the medical care of fellow comrades in arms.     Follow Us on Social Media Twitter: @wardocspodcast Facebook: WarDocs Podcast Instagram: @wardocspodcast LinkedIn: WarDocs-The Military Medicine Podcast YouTube Channel: https://www.youtube.com/@wardocspodcast

In this powerful and eye-opening episode, world-renowned neurosurgeon Dr. Charlie Teo joins us to explore the most complex and misunderstood organ in the human body: the brain. From memory and movement to emotion and decision-making, our brains are truly super-computers—yet most of us know shockingly little about how to protect them. Dr. Teo sheds light on the current brain health crisis, revealing that dementia is now the leading cause of death for Australian women, and delves into the hidden dangers of traumatic brain injuries (TBIs)—often overlooked but with life-altering consequences. We explore how everyday habits—like chronic stress, screen time, poor diet, and social isolation—are quietly damaging our brain function. Dr. Teo also introduces Cingulum Health, his innovative brain clinic, offering cutting-edge tools like fMRI assessments and TMS therapy to personalise and transform brain care. Plus, we hear inspiring recovery stories about Owen Wright and others reminding us that healing is possible with cutting eyes software from Omniscent Key Takeaways: Brain health is in crisis—but it's not too late to act. TBIs can be subtle yet have long-term effects on mood, memory, and cognition. Daily lifestyle choices play a significant role in brain function and longevity. Cingulum Health is pioneering personalised brain care with impressive results. The future of medicine is brain-focused, proactive, and tailored to the individual.

In this episode, I sit down with Carl Monger, founder of GallantFew and licensed counselor, to talk about healing, leadership, and rebuilding life after trauma. We dive into veteran transition, EMDR vs exposure therapy, the truth about TBIs, and how owning your story can change your life.Whether you're a veteran or just feeling lost, this one will hit home.

In this episode, Dr. Pilar Vergara tells how she came to write the book Crossed and Lazy Eyes, Myths, Misconceptions and Truths. She shares that science backs up new ways to treat amblyopia and TBIs and how lives are changed as people receive appropriate treatement. Dr. Vergara is a true leader in behavioral optometry and vision development. Based in Albacete, Spain, she's spent over 30 years helping people of all ages improve their visual function—from children struggling in school to adults recovering from brain injuries. Dr. Vergara is a global educator, author of several influential books on vision and learning, and the first Spaniard to be named a Fellow in multiple international optometry organizations. She brings a deep understanding of how vision impacts our lives and a passion for helping people see—not just with their eyes, but with their whole brain.Dr. Vergara's website: https://pilarvergara.esAccess the book Crossed and Lazy Eyes, Myths, Misconceptions and Truths here: https://www.amazon.com/Crossed-lazy-eyes-misconceptions-truths-ebook/dp/B0854KX1Z4/ref=sr_1_1?crid=DI0JGKL6171F&dib=eyJ2IjoiMSJ9.TdGV_CLmwvfpoI4fuJG9AcBm5URe52X7s7d3DScnj1i7562qYGoTHKBeRWt9hsF2.-PzugOMoz-gyAgiKDOMzQQWYlZliSURVLJki1ebUzC8&dib_tag=se&keywords=crossed+%26+lazy+eyes&qid=1744956809&sprefix=crossed+%26+lazy+eye%2Caps%2C449&sr=8-1Dr. Vergara's book: Tanta Inteligencia, tan poco rendimiento (available in Spanish on her website and Amazon/Spanish)https://pilarvergara.es/libro-tanta-inteligencia-tan-poco-rendimiento/English Testimonial on her website:https://pilarvergara.es/a-beautiful-story-of-love-one-that-goes-far-beyond-optometry/Brain Injury information on NORA website: https://noravisionrehab.org/patients-caregivers/about-brain-injuries-visionIf you liked this episode, click here to send me a message. I also appreciate guest and topic suggestions.Click the link above to message me directly. It comes to me as FAN MAIL! How great is that? Just click on the place that says, "If you liked this episode CLICK HERE:"

 Was It Trauma...or a Brain Injury? In this raw, in-the-car episode, I open up about something I've never fully talked about — the invisible symptoms of post-concussion syndrome and how they've affected my life and recovery. After overdoing it on a bike ride, I fell into a physical and cognitive relapse that left me confused, exhausted, and deeply frustrated. I now know it was a resurgence of TBI symptoms, something that often gets overlooked in women, especially those with a history of domestic abuse. This isn't medical advice — it's my personal story. But if any of this sounds familiar to you, it might be worth exploring further.

This month, we're welcoming Laurel Thornton, (MA, LPC, ALPS, EMDR CERTIFIED), back to the pod to discuss the implications of Traumatic Brain Injury in Domestic Violence Situations. Laurel joined us last year to talk about Neurodiversity and Trauma, and we love the way she conceptualizes the possibilities for innovation and trauma-informed practice in brain health. Listen along as we talk about how to identify and address TBIs in the people we serve and how to better our community response to DV with education and intervention. Laurel is a Neuropsychotherapist, Owner of Whole Brain Solutions, and Co-Founder of the Whole Brain Institute. You can learn more about her work at wholebrainsolutionswv.com. We're particularly excited about Whole Brain Institute's new podcast, The Why We Are, and hope you check out their first episode streaming live now. Branches Domestic Violence Shelter has been providing services to victims of domestic violence in the Appalachian communities of Cabell, Lincoln, Mason, Putnam, and Wayne counties in West Virginia.Let's Be Friends! On FacebookOn InstagramSign up for our NewsletterOr Donate.

Could your unexplained thyroid symptoms be traced back to a brain injury you barely remember?Dr. Eric reveals the link between brain trauma and thyroid dysfunction that most medical professionals overlook. TBIs can compromise the brain's control center for thyroid function, leading to central hypothyroidism and impaired recovery. Beyond direct damage, brain injuries trigger inflammatory responses that potentially initiate autoimmune processes affecting thyroid health. If you've ever suffered a concussion or head trauma, this is an episode that you can't miss. Understanding the connection between brain injuries and thyroid health could be the answer to your healing journey.Episode Timeline: 0:01 – Podcast Intro0:34 – Opening the Q&A on Brain Injuries and Thyroid Health0:52 – Examining the Link Between Brain Injuries and Autoimmunity1:13 – Key Insights From "The Role of Autoimmunity After Traumatic Brain Injury"1:30 – How TBI Damages Brain Cells and Disrupts the Blood-Brain Barrier2:20 – Can TBI Trigger Autoimmune Reactions? What Research Says3:06 – The Possibility of TBI Contributing to Thyroid Dysfunction3:24 – Why Brain Injuries Are Linked to Central Hypothyroidism3:43 – Understanding the Hypothalamic-Pituitary-Thyroid (HPT) Axis4:23 – The Critical Role of Thyroid Hormones in Brain Recovery5:01 – Exploring the Brain-Gut Connection and the Vagus Nerve5:23 – How Leaky Gut and Leaky Brain Can Lead to Brain Fog6:04 – A Look at Cyrex Labs and Testing for Leaky Brain6:37 – Final Takeaways on Brain Injuries and Thyroid Health7:20 – Podcast OutroMentioned in this Episode: Journals & Articles: The role of autoimmunity after traumatic brain injury Thyroid Hormone and the Brain: Mechanisms of Action in Development and Role in Protection and Promotion of Recovery after Brain InjuryFree resources for your thyroid healthGet your FREE Thyroid and Immune Health Restoration Action Points Checklist at SaveMyThyroidChecklist.comHigh-Quality Nutritional Supplements For Hyperthyroidism and Hashimoto'sHave you checked out my new ThyroSave supplement line? These high-quality supplements can benefit those with hyperthyroidism and Hashimoto's, and you can receive special offers, along with 10% off your first order, by signing up for emails and text messages when you visit ThyroSave.com. Do You Want Help Saving Your Thyroid?Click Here to access hundreds of free articles and blog posts.Click Here for Dr. Eric's YouTube channelClick Here to work with Dr. Eric Do You Want Help Saving Your Thyroid? Access hundreds of free articles at www.NaturalEndocrineSolutions.com Visit Dr. Eric's YouTube channel at www.youtube.com/c/NaturalThyroidDoctor/ To work with Dr. Eric, visit https://savemythyroid.com/work-with-dr-eric/

Our second March episode shines a spotlight on a national treasure – the Elizabeth Dole Foundation and its comprehensive work to support the family caregivers of veterans. I talked with three of the executives with the EFD about their programs, including the Hidden Heroes program and the Dole Caregiver Fellows, as well as talked with a Dole Caregiver Fellow and her journey through the health care system with her veteran husband who suffered a TBI while on active duty. And, since March is also National Traumatic Brain Injury Month, I also talk to Dr. Gail Anderson of the Brooks Rehabilitation Hospital in Florida about what to know about TBIs and how to communicate with a loved one who has a TBI. (6:13) – Dr. Roxana Delgado – Dole Caregiver Fellow – shares her caregiving journey with a veteran husband who suffered a TBI on active duty and as she says, “how to go from tragedy to triumph.” 38:53) Liz Rotenberry – Director of Caregiver Engagement for the Elizabeth Dole Foundation – talks about how to become a Dole Caregiver Fellow, mental health programs and more. (1:07:36) Marianne Delatorre - Community Engagement Manager, Hidden Heroes program of the Elizabeth Dole Foundation – tells us more about this program for caregivers locally and nationwide (1:38:10) – Dr. Gail Anderson of Brooks Rehabilitation Hospital – explains the spectrum of traumatic brain injury (TBI) and how to communicate with a loved one with TBI Take Care and Stay Well! Find out more at: caregivingclub.com/podcast/

Methylene blue (MB) has gained some massive exposure the last couple of months and is seemingly one of the hottest topics; and not just in biohacking and longevity circles, but even amongst general health and wellness enthusiasts. This exponential rise in MB is largely due to a handful of viral social media posts the last couple of months, which then prompted many influencers and/or medical professionals to voice their opinions and/or concern surrounding MB. There is some great info being circulated, but, needless to say, there is also a lot of misinformation being propagated.I wanted to take to the mic and address some of this misinformation and concern head-on. One issue that I see arise is around the quality of MB and, more specifically, the fact that MB can be derived from petroleum substances. Notice how I said, "can be." Yes, different industrial use cases may obtain their MB from petroleum-based sources, but is not the same MB that would be considered safe for human consumption. Also, there is a notion going around that you can make "homemade" leucomethyene blue simply be adding vitamin C to MB. I explain why this is a half-truth and does not lead to the same quality, purity, stability, bioavailability or effectiveness in mitochondria.The study covered in today's episode demonstrates how the mitochondria are being recognized as an integral therapeutic target for traumatic brain injuries (TBIs). That would mean  a.) mitochondrial dysfunction is a large part of the brain damage (and, thus, recovery) associated with TBIs and, presumably, other head trauma, such as concussions; and b.) anything that can improve mitochondrial function, particularly things that can positively affect the brain, has a large potential role to play in the recovery from TBIs and other head trauma. The Mitochondrial Triad ticks all of those boxes. If you found the information in today's episode particularly interesting and/or compelling, please share it with a family member, friend, colleague and/or anyone that you think could benefit and be illuminated by this knowledge. Sharing is caring :)As always, light up your health! - Key Points: 1:24 - Health Optimisation Summit Announcement4:06 - Return to Nature announcement5:56 - Methylene blue controversy7:40 - Qualities of Methylene Blue8:29 - Industrial Qualities of Methylene Blue9:08 - Pharmaceutical-grade Methylene Blue11:20 - Evaluating Methylene Blue as a consumer11:53 - Clear Methylene Blue13:09 - Vitamin C effect on Methylene Blue14:48 - Low-quality Methylene Blue vs. Pharmaceutical Grade17:46 - Methylene Blue + Vitamin C vs. Ultra-pure Pharmaceutical-Grade MB effectiveness22:16 - Tips for using Vitamin C Methylene Blue23:30 - Is there such a thing as too much antioxidant protection?25:12 - Do you own research/safety of methylene blue25:54 - Mitochondrial Dysfunction vs Anti-Synthetic sentiment26:36 - Will my Organs Turn Blue?27:55 - Ramifications of non-native EMFs30:02 - Toxicity of our Environment30:44 - Necessity of Improving Mitochondrial Function31:12 - Importance of Methylene Blue33:45 - Mitochondrial Therapy in Brain Injury40:31 - Final thoughts - Upcoming BioLight Events:   Health Optimisation Summit (Biohacking Conference), April 12 - 13 (Austin, TX)   Returning to Nature (Quantum Health Retreat), June 26 - 27 (Franklin, TN) - Articles referenced in episode:   Mitochondria as a Therapeutic Target: Focusing on Traumatic Brain Injury - Save 25% when you Subscribe & Save to a BioBundle!   For a BioBundle, you choose:1.) Any one BioBlue supplement(BioBlue, BioBlue (SR), BioBlue Leuco, BioBlue Calm, BioBlue Capsules or BioBlue Leuco Capsules)2.) Any one BioC60 supplement(Regular or Concentrated)   The BioBundle automatically saves you 15% on both of the supplements you choose.You save an additional 10% by choosing to Subscribe & Save to that BioBundle.The 25% savings is passed along for every monthly delivery of your BioBundle!No discount code necessary!   Click here to check out The BioBundle - Dr. Mike's #1 recommendations: Water products: Water & Wellness Grounding products: Earthing.com EMF-mitigating products: Somavedic Blue light-blocking glasses: Ra Optics - Stay up-to-date on social media: Dr. Mike Belkowski: Instagram LinkedIn   BioLight: Website Instagram YouTube Facebook

American-Made, all natural, powerful wellness tech patented to reverse aging was designed for Navy SEALs. This incredible Star Trek-like breakthrough has now hit the mass market. Join Brad Wozny, Michael Jaco and serial entrepreneur Connie Lucas as they unpack these radical, MAHA blessed wearable med bed patches which activate your stem cells -- they work so well even RFK Jr, Mike Tyson, NCAA teams and Warrior Grannies in 100 countries are wearing it with testimonies pouring in non-stop!   Given the power of this technology, we invite all listeners in the audience to share this far and wide. . X39 - http://www.catchthelifewave.com/promo The MAHA-Approved, POWERFUL X39 wellness Patch naturally activates your STEM CELLS! Developed for Navy

Traumatic Brain Injury is a major cause of death, disability, and cognitive decline. Thankfully, evolving research is helping us protect our heads and lessen the long-term impacts of TBIs. In this episode of ‘Your Brain On...' we discuss: • The effects and symptoms of TBI, from mild concussions to more severe head injuries • What actually happens to your brain when you sustain a TBI • The links between TBI and neurodegenerative diseases and cognitive impairment • The prevalence of TBI in military personnel and sportspeople, and how we're improving protective technologies • Steps to take after experiencing concussions or head traumas • How brain-healthy preventative lifestyle habits can lessen the long-term impacts of TBI Our guest for this episode is Dr. David Brody, MD, PhD, Chief Science Officer/Chief Innovation Officer, Center for Neuroscience and Regenerative Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD. Dr. Brody is a pre-eminent researcher of traumatic brain injuries, particularly in military personnel who experience TBIs during combat.  This is... Your Brain On TBI. ‘Your Brain On' is hosted by neurologists, scientists, and public health advocates Drs. Ayesha and Dean Sherzai. ‘Your Brain On...' is supported by the NEURO World Retreat, taking place in San Diego, September 2–5 2025: https://neuroworldretreat.com/ ‘Your Brain On... TBI' • SEASON 4 • EPISODE 8  — LINKS David Brody, MD, PhD: https://www.usuhs.edu/profile/david-brody-md-phd  — FOLLOW US  Instagram: @thebraindocs  Website: TheBrainDocs.com More info and episodes: TheBrainDocs.com/Podcast

THE VIBE with Kelly Cardenas presents Leigh Steinberg, premier sports agent, entrepreneur, and Chairman and founder of Steinberg Sports and Entertainment, is best known for his work building athletes into stand-alone brands. Often credited as the real-life inspiration for the Oscar-winning film Jerry Maguire, Leigh has represented some of the most successful athletes and coaches across football, basketball, baseball, hockey, boxing, golf, and more. He holds an unprecedented record of representing the number one overall pick in the NFL draft eight times, along with 64 total first-round picks, and represented 12 Hall of Famers. Beyond football, his clients include Oscar De La Hoya, Lennox Lewis, multiple Olympians, and professional teams. With a history of record-setting contracts, he has secured over $4 billion for more than 300 pro athlete clients while directing over $1 billion to various charitable causes worldwide. CNN, Fox Business, Fox and Friends, Lifestyle of the Rich & Famous Born and raised in Los Angeles, Leigh's early life was shaped by his parents—a teacher and librarian. He earned his B.A. in political science and J.D. from UC Berkeley, where he served as student body president during both degrees. His cultural significance extends beyond the sports world; Leigh has been a trivia question on both Jeopardy! and Trivial Pursuit, cementing his iconic status. Deeply committed to philanthropy, Leigh has been recognized for his charitable work with numerous commendations, including honors from Congress, state legislatures, multiple U.S. Presidents, and various civic organizations. His accolades include being named “Man of the Year” over a dozen times and receiving “Keys to the City” in several U.S. cities. He also played a pivotal role in saving the San Francisco Giants, earning him the honor of “Leigh Steinberg Day” in the city. In 2017, he was inducted into the California Sports Hall of Fame. Throughout his career, Leigh has been a prominent media figure, appearing on programs like 60 Minutes, Larry King Live, The Today Show, CNN, Fox Business, Fox & Friends, Lifestyles of the Rich and Famous, and Real Sports with Bryant Gumbel. His profile has graced the pages of Business Week, Sports Illustrated, Forbes, GQ, and ESPN the Magazine. As a consultant, he contributed to films and shows such as Jerry Maguire, Any Given Sunday, For Love of the Game, and Arli$$. He also provides expert commentary on sports business through outlets like The Dan Patrick Show and The Herd with Colin Cowherd. A prolific writer, Leigh contributes columns to Forbes, HuffPost, and Daily Pilot and has authored notable works such as Winning with Integrity and The Agent: My 40-Year Career of Making Deals and Changing the Game. Leigh's passion for improving athlete health and safety has led him to host annual Brain Health Summits, uniting athletes, medical experts, and researchers to address traumatic brain injuries (TBIs). These summits focus on advancements in diagnosis, prevention, and mental health support. Additionally, Leigh has championed initiatives in sustainability and community development through partnerships with various organizations. His efforts include launching educational programs for underserved communities, promoting clean energy in sports facilities, and developing outreach projects aimed at creating long-term social impact. His multifaceted projects reflect his dedication to driving meaningful change both within and beyond the sports world. SUBSCRIBE TO MY SUBSTACK https://thevibebykellycardenas.substack.com?r=4nn6y5&utm_medium=ios BUY THE VIBE BOOK ⁠https://a.co/d/6tgAJ4c⁠  BUY BLING ⁠https://shop.kellycardenas.com/products/kelly-cardenas-salon-bling⁠  SUPPORT HIGH FIVES FOUNDATION ⁠https://highfivesfoundation.org/⁠  EXECUTIVE PRODUCER - BROOKLYN CARDENAS ⁠https://www.brooklyncardenas.com/⁠

Trigger Warnings:- Discussion of PTSD and mental health challenges- Mention of combat experiences and deployments In this episode, retired U.S. Army veteran Mike “TaylorLyfe” Taylor shares his powerful journey of transitioning from military life to entrepreneurship and finding renewed purpose. Mike candidly discusses the challenges he faced, including PTSD, TBIs, and the complexities of navigating the VA system, while also highlighting the importance of community, mentorship, and discovering new passions. Through his inspiring story, Mike emphasizes the value of resilience, positive mindset, and giving back to others, offering insights that will resonate with listeners navigating their own transitions. Connect with Mike through the links below: Facebook: https://www.facebook.com/profile.php?id=100009704088932&mibextid=ZbWKwL Mikes LinkTree: https://linktr.ee/mike.taylor357 TaylorLyfe Digital Marketing: https://www.facebook.com/taylorlyfemarketing Chaotic Chronicles Linktree: https://linktr.ee/Chaotic.Chronicles?subscribe Chaotic Chronicles Website: https://www.chaoticchronicles.com   Dungeon Scribe Society Patreon: https://www.patreon.com/dungeonscribesociety   SideQuest! Podcast/Website: https://paladinsofpodcast.com https://sidequests.buzzsprout.com https://open.spotify.com/show/1opGILqLXGYKfFyR02kQOs?si=4974ca6d39644a07 ____________________________________________________________ If you are experiencing suicidal ideations or have experienced sexual assault and need help or someone to talk to, please reach out to the National Suicide Prevention Lifeline at 988 or the National Sexual Assault Hotline at 1-800-656-4673** **Any views discussed in this episode are strictly personal views and not views of the United States military. This podcast is in no way affiliated with any branch of the United States military. Some names have been changed in order to protect the identities of speakers and/or names mentioned throughout episodes. Subscribe to the podcast on ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠YouTube⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Support the podcast on ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Patreon⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.ysdeh.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Sign the petition for Better Mental Health Care in the United States Navy here: h⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ttps://chng.it/z2M6WR2WcM⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Follow Your Story Doesn't End Here on IG at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/_ysdeh/ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ FB: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.facebook.com/ysdeh⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Today, we have an intriguing topic that ties directly into chiropractic care—mild traumatic brain injury (TBI). We're diving into a groundbreaking study that examines the effects of chiropractic intervention on ocular motor and attentional visual outcomes in young adults with long-term mild TBI. We'll break down the study's findings, explore how to apply them in your practice, and discuss the critical role chiropractic care can play in managing TBIs, especially those resulting from motor vehicle accidents and sports injuries.Episode Notes: Effect of Chiropractic Intervention on Oculomotor and Attentional Visual Outcomes in Young Adults With Long-Term Mild Traumatic Brain InjuryThe Best Objective Assessment of the Cervical Spine- Provide reliable assessments and exercises for Neuromuscular Control, Proprioception, Range of Motion, and Sensorimotor-Integration. Learn more at NeckCare.comTurncloud EHR- Minimalist design, without being sparse. Practical, yet elegant. Turncloud's design was to find the most efficient path in a day in the life of a chiropractic office. Connect with their team at www.turncloud.com Patient Pilot by The Smart Chiropractor is the fastest, easiest to generate weekly patient reactivations on autopilot…without spending any money on advertising. Click here to schedule a call with our team.Our members use research to GROW their practice. Are you interested in increasing your referrals? Discover the best chiropractic marketing you aren't currently using right here!

In this Iron Culture/Sports Nutrition Association/Sigma Nutrition Radio crossover episode, host Eric Trexler is joined by co-host Danny Lennon and guest Dr. Shawn Arent. Dr. Arent is a professor and department chair at the University of South Carolina with a wealth of knowledge and research experience pertaining to nutritional strategies and supplements purported to support brain health and function. In this meeting of the minds, Eric, Danny, and Dr. Arent discuss the brain-related effects of carbohydrate, amino acids, caffeine (and caffeine-related substances), theanine, nicotine, fish oil, creatine, and much more. If you're interested in preserving the health and function of your brain, listening to this episode is certainly a smart decision. 00:00 Introduction to another crossover episode and Dr Shawn Arent 03:20 Defining cognitive performance and function 07:48 The acute effects of carbohydrates and caffeine on fatigue 13:01 Carbohydrate mouth rinsing and glycogen depletion (and are bodybuilders athletes?) 26:15 The (non-linear) glycogen utilisation response to exercise 29:53 The role of protein (EAAs and BCAAs) on cognitive function  Daivs 1999 Effects of branched-chain amino acids and carbohydrate on fatigue during intermittent, high-intensity running https://pubmed.ncbi.nlm.nih.gov/10452228  36:06 Caffeine dose-response relationship on cognition 40:50 Caffeine timing and dosing strategies 51:38 Optimisation and thinking outside the box to minimise the effects of caffeine on sleep 55:18 Other (interesting) supplements with less evidence 1:01:28 Nicotine and sports culture 1:08:52 Supplementation for brain health and recommendations/protocols for TBIs 1:21:22 Closing out with some final take homes

Traumatic brain injuries (TBI) can have a devastating impact on your health—and many people don't even know it. In this video, I discuss how TBIs can lead to low testosterone and other hormone imbalances, especially for veterans and those with undiagnosed injuries. Learn about the hidden dangers of brain injuries, the symptoms to look out for, and why getting your hormones tested could save your life. If you're feeling unexplained fatigue, depression, or low energy, this could be the missing link. --- Support this podcast: https://podcasters.spotify.com/pod/show/nickkoumalatsosshow/support

Today, we're going in depth on traumatic brain injuries. James Tytko speaks with Dawn Astle, daughter of former England striker Jeff Astle, about the finding that his death was linked to head trauma sustained during his playing career. Also, Prof Peter Hutchinson gives an overview of head injuries, and Adel Helmy talks about changing the rules of some sports to reduce risk. Then, Alexis Joannides describes one of many new technological innovations to support medical staff dealing with TBIs, before Prof David Menon describes the path towards better drug treatments and diagnostic tools. If you... Like this podcast? Please help us by supporting the Naked Scientists