Podcasts about Induction

Dr Hugo Stephenson, Joint-CEO of Induction Healthcare, said: The Group has generated excellent commercial momentum in the first half of the current financial year and has delivered its first full year of revenues. I am particularly excited by our momentum with customers, such as the first NHS contract in South Wales for Induction Switch, and admission onto the NHSX Clinical Communications Framework. We are proud to work in collaboration with Apple and Milton Keynes Hospital NHS Trust on a 'first of type' NHS innovation, enabling patients to view their Health Records on their own iPhone. Our acquisitions continue to perform and integrate well, as shown by MicroGuide achieving its earn-out ahead of schedule. We have an exciting and active pipeline of acquisition opportunities which will further enhance the product offering of the Group. "Ongoing growth in user engagement, amongst doctors and patients alike, is testament to the value healthcare stakeholders are getting across the range of Induction products. This progress, allied to our robust balance sheet, future contracted revenue, a major collaboration with Cerner and NHSX Clinical Communications framework supports confidence of further progress in the remainder of the financial year. https://www.share-talk.com/dr-hugo-stephenson-ceo-induction-healthcare-group-plc-inhc-l-interview/

Welcome to this bonus episode of Motherness. If you’re part of my private Facebook group for the podcast then you’ll know that season two is coming in January but given it’s been slightly longer between seasons than I’d initially planned, I wanted to drop a new episode so you can get a little Motherness fix while you wait!In today’s episode, I speak with midwife and mum of one Tash Porter about her entry to motherhood with her daughter Milly. If you’re a mum, like me, who had a baby who didn’t have reflux or colic, you likely suffered the typical amount of sleep deprivation in the first year or two of their life. But for a mum like Tash, whose daughter did have reflux, she was forced to survive on one hour of sleep – total – each night and one nap per day. After listening to her today, you’ll have a whole new appreciation and understanding for those parents who battle a similar journey. Despite all that Tash went through in their first year, she is incredibly pragmatic and somehow positive about a time that I truly believe would break many of us. So, if you’re listening and you’re in the trenches of a challenge then this is for you. For you, the mum who feels a little lonely even with a community, the mum who feels like she can’t leave the house, the mum who’s only just surviving. We see you and this episode is for you. Mental health support services:Perinatal Anxiety & Depression Aotearoa depression.org.nz or 0800 111 757Mental Health FoundationParent Help - 0800 568 856 Anxiety Phone Line - 0800 269 4389 PlunketLine - 0800 933 922 Follow Tash Porter on Instagram.Follow Skye Ross on Instagram. Follow Motherness on Instagram.

Our final episode of ROCpod for this year is an instalment of our Good Governance in Practice series about managing conflicts of interest. Officers of registered organisations have a responsibility to carry out their duties in good faith and in the best interests of the organisation. A personal interest may come into conflict with this responsibility. However through good governance, organisations can identify and manage conflicts of interest. In our latest podcast we draw on examples of case law and whistleblower disclosures to illustrate the potential consequences of conflicts of interest and suggest practical strategies for responding to them.

Yamanaka Factors for the Cardio-Oncologist Dr RR Baliga's 'Got Knowledge Doc' Podkasts for Physicians Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell. 2006 Aug 25;126(4):663-76. doi: 10.1016/j.cell.2006.07.024. Epub 2006 Aug 10. PMID: 16904174. Sharma A. Stem cells to help the heart. Science. 2020 Mar 13;367(6483):1206. doi: 10.1126/science.aba6111. PMID: 32165579.   Sayed N, Ameen M, Wu JC. Personalized medicine in cardio-oncology: the role of induced pluripotent stem cell. Cardiovasc Res. 2019 Apr 15;115(5):949-959. doi: 10.1093/cvr/cvz024. PMID: 30768178; PMCID: PMC6933506.   Yoshida Y, Yamanaka S. Induced Pluripotent Stem Cells 10 Years Later: For Cardiac Applications. Circ Res. 2017 Jun 9;120(12):1958-1968. doi: 10.1161/CIRCRESAHA.117.311080. PMID: 28596174.   Lu Y, Brommer B, Tian X, Krishnan A, Meer M, Wang C, Vera DL, Zeng Q, Yu D, Bonkowski MS, Yang JH, Zhou S, Hoffmann EM, Karg MM, Schultz MB, Kane AE, Davidsohn N, Korobkina E, Chwalek K, Rajman LA, Church GM, Hochedlinger K, Gladyshev VN, Horvath S, Levine ME, Gregory-Ksander MS, Ksander BR, He Z, Sinclair DA. Reprogramming to recover youthful epigenetic information and restore vision. Nature. 2020 Dec;588(7836):124-129. doi: 10.1038/s41586-020-2975-4. Epub 2020 Dec 2. PMID: 33268865.   Litviňuková M, Talavera-López C, Maatz H, Reichart D, Worth CL, Lindberg EL, Kanda M, Polanski K, Heinig M, Lee M, Nadelmann ER, Roberts K, Tuck L, Fasouli ES, DeLaughter DM, McDonough B, Wakimoto H, Gorham JM, Samari S, Mahbubani KT, Saeb-Parsy K, Patone G, Boyle JJ, Zhang H, Zhang H, Viveiros A, Oudit GY, Bayraktar OA, Seidman JG, Seidman CE, Noseda M, Hubner N, Teichmann SA. Cells of the adult human heart. Nature. 2020 Sep 24:1–7. doi: 10.1038/s41586-020-2797-4. Epub ahead of print. PMID: 32971526; PMCID: PMC7681775.

Featuring perspectives from Drs Sagar Lonial and Krina K Patel, including the following topics: Existing Management Paradigm for Multiple Myeloma (MM) — Sagar Lonial, MD (0:00) Selection and sequencing of systemic therapies for patients with relapsed/refractory MM (15:14) Follow-up discussion with Dr Love and Dr Lonial (18:16) Future Directions in MM Treatment — Krina K Patel, MD, MSc (24:53) Follow-up discussion with Dr Love and Dr Patel (53:48) Case: A woman in her late 70s with multiple regimen-refractory MM receives belantamab mafodotin on a clinical trial (59:02) Case: A woman in her early 70s with relapsed/refractory MM receives B-cell maturation antigen (BCMA)-directed chimeric antigen receptor (CAR) T-cell therapy (1:03:43) Case: A man in his early 50s with relapsed/refractory t(11;14) MM receives venetoclax in combination with carfilzomib and dexamethasone on a compassionate-use basis (1:07:43) Induction and maintenance therapy for newly diagnosed MM (1:13:17) Management of relapsed/refractory disease (1:39:16) FDA approval of the antibody-drug conjugate belantamab mafodotin and role of BCMA-directed CAR T-cell therapies in MM (1:48:50) Future developments and novel investigational approaches in MM (2:04:46) CME information and select publications

Malur Narayan is a proven technology business leader having distinguished himself through his broad business experience in software, telecom, networking and IT products and services. Malur is also actively involved with several startups as an advisor, investor, and a mentor – specifically as co-founder of BoardSeatMeet, an online platform for diversity in Boards, and with Webware.io, a toolkit to help businesses go online. He has over 28 years of industry experience having worked in all five continents. He has held a broad range of senior management roles at Nortel and Tata ranging from sales, business development, product management & marketing, and product development/engineering. Malur was in a senior leadership role, reporting to the CEO of TCS, to bring TCS's technology solutions to benefit the Tata group companies — specifically digital transformation — including a Big Data Customer insight program. Malur pioneered self-managed teams in software development in the early 90s. His research in Reverse Engineering, Inverse resolution and Induction led to the introduction of Adaptive learning algorithms in Machine Learning in 1991. Malur holds an undergraduate degree in Computer Engineering, a Master’s degree in Computer Science from University of Western Ontario, Canada and a MBA from the University of Ottawa, Canada. He began his career as a software engineer at Nortel. He has been a speaker at several International business forums including EMBA programs at Cornell University, Imperial College of London, IIM-Ahmedabad and Queens University in Canada. He is known for his positive attitude, people skills, great sense of humor, and is immensely passionate about trail hiking/running, creating music, gardening and writing. He is actively involved in charitable activities for mental health care and awareness. His story on building relationships and personal brand has recently been featured in a book titled “Get your Next Promotion”, by Manbir Kaur Malur is based in Austin, Texas. --- Support this podcast: https://anchor.fm/freeman-means-business/support

Jasmine was 41 weeks pregnant, and about to give birth to her first child, when her brother suddenly and unexpectedly passed away. She tells us the story of what it was like to be induced and give birth while dealing with the whirlwind of stress, emotions, and grief.  Jasmine also shares the story of her second birth which was near a completely opposite experience, at home, and was (as so many subsequent births often are), a healing experience.  Follow Jasmine! @thebirthzone

In episode 106 of Kiwi Birth Tales I speak with Rebecca about the surrogacy birth story of baby Ziggy (parents Tess & Dan). In this episode we cover: - surrogacy - pre eclampsia- induction (misoprostol oral drug) - water birth - post birth haemorrhage- haemorrhoids- mental health / post birth hormones This episode is proudly brought to you by Noopii. Noopii® is an award-winning New Zealand and women-owned Social Enterprise company making premium eco luxe nappies and pants that are non-toxic, chemical-free and made with Manuka Hydrosol - a world first. By harnessing this ‘plant power’ with the latest technology they have created nappies that are naturally antibacterial which may inhibit the growth of bacteria, preventing nappy rash.Follow on Instagram @noopiinzFollow on Facebook: facebook.com/noopii.co.nzWebsite: www.noopii.co.nz

Today, Mila & Shawn share their baby’s pre-pandemic, premature birth story. In the weeks leading up to Mila’s labor, the couple had been chosen to be on the tv show HOUSE HUNTERS. However, Mila’s water breaks at 36 weeks before they even finish shooting the episode. While Mila, who had done a lot of work to reduce her anxiety and build trust in the birth process, had hoped for an unmedicated labor, the way things play out induction and then pain medications ended up being needed. They share how Mila pushed for 3 hours, and just as things were headed for a c-section, Shawn asked if the vacuum was an option because Mila really wanted to avoid a surgical birth. So, a vacuum was used to assist with the delivery. Then they explain how baby went to the NICU for 6 days due to some breathing issues and needing phototherapy for jaundice. Mila discusses the helpful early breastfeeding support she received in the hospital, and also shares already preferring to having an out-of-hospital birth attended by a midwife and a doula for the next time around.

In this episode, I will talk about cervical ripening, the Bishop score, and some "mechanical" ways to ripen the cervix. More specifically, we'll talk about the advantages and disadvantages of cervical osmotic dilators (including Dilapan-S®), and using the Foley balloon for cervical ripening. Get on the wait list for the Pocket Guide here: https://evidencebasedbirth.com/pocket-guide-wait-list/ References on Cervical Ripening: Curran, M. (2020). Bishop Score Calculator. Click here. Kolkman, D. G. E., Verhoeven, C. J. M., Brinkhorst, S. J., et al. (2013). Bishop score as a predictor of labor induction success: a systematic review. American Journal of Perinatology, 30(8), 625-30. Click here. Ivars, J., Garabedian, C., Devos, P., et al. (2016). Simplified Bishop score including parity predicts successful induction of labor. Eur J Obstet Gynecol Reprod Biol., 203, 309-314. Click here. References on the Foley: Abdelhakim, A. M. Shareef, M .A., AlAmodi, A. A., et al. (2020). Outpatient versus inpatient balloon catheter insertion for labor induction: A systematic review and meta-analysis of randomized controlled trials. Journal of Gynecology Obstetrics and Human Reproduction, In Press. Click here. Alfirevic, Z., Keeney, E., Dowswell, T., et al. (2016). Methods to induce labour: a systematic review, network meta-analysis and cost-effectiveness analysis. BJOG., 123(9), 1462-1470. Click here. American College of Obstetricians and Gynecologists (2009, Reaffirmed 2019). ACOG Practice Bulletin No. 107: Induction of labor. Obstet Gynecol.,114(2 Pt 1), 386-397. Click here. de Vaan, M. D. T., ten Eikelder, M. L. G., Jozwiak, M., et al. (2019). Mechanical methods for induction of labour.
Cochrane Database of Systematic Reviews 2019, Issue 10. Art. No.: CD001233. Click here. Dong, S., Khan, M., Hashimi, F., et al. (2020). Inpatient versus outpatient induction of labour: a systematic review and meta-analysis. BMC pregnancy and childbirth, 20(1), 382. Click here. Leduc, D., Biringer, A., Lee, L., et al. (2013). Induction of Labor: SOGC Clinical Practice Guideline. No. 296, 35(9), 840-857. Click here. Liu, X., Wang, Y., Zhang, F., et al. (2019). Double- versus single-balloon catheters for labour induction and cervical ripening: a meta-analysis. BMC pregnancy and childbirth, 19(1), 358. Click here. Simpson, K. R. (2020). Cervical Ripening and Labor Induction and Augmentation, 5th Edition. AWHONN Practice Monograph, 24(4), PS1-S41. Click here. References on Dilapan-S: American College of Obstetricians and Gynecologists (2009, Reaffirmed 2019). ACOG Practice Bulletin No. 107: Induction of labor. Obstet Gynecol.,114(2 Pt 1), 386-397. Click here. Levine, L. D., Valencia, C. M. and Tolosa, J. E. (2020). Induction of labor in continuing pregnancies. Best Pract Res Clin Obstet Gynaecol., S1521-6934(20), 30079-1. Click here. Gupta, J., Chodankar, R., Baev, O., et al. (2018). Synthetic osmotic dilators in the induction of labour-An international multicentre observational study. Eur J Obstet Gynecol Reprod Biol., 229, 70-75. Click here. Saad, A. F., Villarreal, J., Eid, J., et al. (2019). A randomized controlled trial of Dilapan-S vs Foley balloon for preinduction cervical ripening (DILAFOL trial). Am J Obstet Gynecol., 220(3), 275.e1-275.e9. Click here. For more information and news about Evidence Based Birth®, visit www.ebbirth.com. Find us on Facebook (https://www.facebook.com/EvidenceBasedBirth/), Instagram (https://www.instagram.com/ebbirth/), and Pinterest (https://www.pinterest.com/ebbirth/). Ready to get involved? Check out our Professional membership (including scholarship options) (https://evidencebasedbirth.com/become-pro-member/). Find an EBB Instructor here (https://evidencebasedbirth.com/find-an-instructor-parents/), and click here (https://evidencebasedbirth.com/childbirth-class/) to learn more about the Evidence Based Birth® Childbirth Class.

Kyle Laz is a qualified and passionate herbalist, sound practitioner and intuitive healer… a modern day wizard if you like, and some of us know him as the chocolate wizard.For 15 years Kyle has dedicated his life to deeply researching and exploring plant medicines and their application to body, mind and spirit. He has visited many of the key sacred sites of England and Europe, gaining spiritual and practical knowledge from his experiences, which has allowed him to understand the diverse relationships between western health and spiritual concepts and be able to offer holistic healing in this way. With a strong focus on the five elements, he continues to develop practical processes to recognise, ground and integrate profound, mystical experiences.He works and trains with a range of modalities including Reiki 1, 2 and Master Teacher attunements, Acutonics, Sound Healing, Massage, Flower Essences, Crystal Healing and Chocolate Ceremonies (a fusion of herbal wisdom, sound and chocolate). Come and join this Birdsong…Please support us on Patreon Please leave us a review on iTunesConnect with Caiyuda on InstagramConnect with Caiyuda on FacebookMedicinepath.net/birdsongTIMESTAMPS:[3:58} Pause and presence for the sacred[7:34] Dancing between words and worlds[8:36] Reframing having an addictive personality and being lazy[11:40] What is a chocolate wizard?[13:09] What do you want to be when you grow up?[14:51] The interconnectivity of chocolate[17:00] Chocolate and the plant medicine path[19:20] Chocolate in the name of love[21:37] Conversations between cacao and mushrooms[28:48] Plant intelligence and the intersection of human consciousness[33:14] There is no “bad chocolate”[35:58] Food of the Gods + Sugar + Milk = Evolutionary Seed Spreading[39:11] Chocolate as a gatekeeper into ceremony[43:18] The synergistic intermingling between various herbs and chocolate[46:16] “Phytochemysticism” - as above, so below[48:01] Amplifying energetics with chocolate + herbs + intention[50:27] Energetic exchange between participant, practitioner and chocolate[53:46] Esoteric mysticism chocolate traditions?[56:37] Current day uses of cacao with breathwork, dance and sound[1:00:55] What to keep in mind when buying and using chocolate[1:03:05] Induction into the Secret Chocolate Society[1:07:01] Chocoloate Dreaming Rituals[1:14:30] Connection with self, connection with earthRESOURCES & LINKS:Kyle Laz websiteConnect with Kyle Laz on FBConnect with Kyle Laz on IGKeith’s CacaoThe Chocolate YogiLoco Love Chocolate

In today’s episode, Toni & Peter share their firstborn’s birth story only about 6 weeks after the big day. Originally they had hoped for a completely unmedicated birth. They share how, as they approached and passed the due date, they tried everything under the sun to go into labor spontaneously, to no effect. The unexpected development of needing induction just after 40 weeks due to developing borderline preeclampsia then required some adjusted expectations. You’ll hear how strong self-advocacy techniques were game-changers that Toni & Peter used to delay and, ultimately, avoid using pitocin for labor. They also share how their doula and Peter set up the hospital room in a way that was both meditative and celebratory, including the use of battery-operated candles, aromatherapy, music, and even a hand drum and dancing. As a psychotherapist who specializes in meditation and mindfulness, Toni details how she used those skills and tools to have an almost completely unmedicated, quick 5-hour induced labor in which she pushes the baby out in only 4 pushes. In light of the fact that most inductions are expected to take, on average, 24 hours, and even spontaneous first-time labors take 18 hours on average, this was doubly fast and efficient. Toni gives a couple of insights and recommendations to listeners for early breastfeeding, and they both reflect on the moment of meeting their daughter as well as the monumental transition into parenthood.

Episode 347 is an updated guide to somatropic hormone and GOD did I go crazy on this one! I honestly want to know more about growth hormone than anyone alive and thus, begins this string of GH based guides! I DID finally discuss the MoA for how GH causes localized fat loss which really had me excited since no one in our industry has EVER talked about this so that definitely was an interesting avenue to go down! Below I am going to reference a lot of the literature for this hormone that I was read through over the past few years on this topic so please DO NOT TAKE MY WORD FOR THIS - READ THESE YOURSELF! Keep in mind this is a brief snippet of every bit of literature on the topic however. REFERENCES   Daughaday WH, Rotwein P. Insulin-like growth factors I and II. Peptide, messenger ribonucleic acid and gene structures, serum, and tissue concentrations. Endocr Rev. 1989;10:68–91. [PubMed] [Google Scholar] Jones JI, Clemmons DR. Insulin-like growth factors and their binding proteins: biological actions. Endocr Rev. 1995;16:3–34. [PubMed] [Google Scholar] Le Roith D, Bondy C, Yakar S, Liu JL, Butler A. The somatomedin hypothesis: 2001. Endocr Rev. 2001;22:53–74. [PubMed] [Google Scholar] Melmed S. Endocrinology. 5th edn. Philadelphia: Elsevier Saunders; 2006. pp. 411–428. [Google Scholar] Fain, J. N., García‐Sáinz, JA. (1983) Adrenergic regulation of adipocytes metabolism. J Lipid Res 24: 945– 966. CAS PubMed Web of Science®Google Scholar  Gilman, AG. (1987) G protein: transducer of receptor‐generated signals. Annu Rev Biochem 56: 615– 649. Crossref CAS PubMed Web of Science®Google Scholar  Jimenez, M., Lèger, B., Canola, K., et al (2002) Beta(1)/beta(2)/beta(3)‐adrenoceptor knockout mice are obese and cold‐sensitive but have normal lipolytic responses to fasting. FEBS Lett 530: 37– 40. Wiley Online Library CAS PubMed Web of Science®Google Scholar  Birnbaumer, L., Abramowitz, J., Brown, AM. (1990) Receptor‐effector coupling by G proteins. Biochim Biophys Acta 1031: 163– 224. Crossref CAS PubMed Web of Science®Google Scholar  Spiegel, A. M., Shenker, A., Weinstein, LS. (1992) Receptor‐effector coupling by G‐protein: implications for normal and abnormal signal transduction. Endocr Rev 13: 536– 565. Crossref CAS PubMed Web of Science®Google Scholar  Beebe, S. J., Holloway, R., Rannels, R. S., Corbin, JD. (1984) Two classes of cAMP analogs which are selective for the two different cAMP‐binding sites of type II protein kinase demonstrate synergism when added together to intact adipocytes. J Biol Chem 269: 3539– 3547. PubMed Google Scholar Frank RN. Diabetic retinopathy. N Engl J Med. 2004;350:48–58. [PubMed] [Google Scholar] Tatar M, Bartke A, Antebi A. The endocrine regulation of aging by insulin-like signals. Science. 2003;299:1346–1351. [PubMed] [Google Scholar] Ibrahim YH, Yee D. Insulin-like growth factor-I and cancer risk. Growth Horm IGF Res. 2004;14:261–269. [PubMed] [Google Scholar] Laban C, Bustin SA, Jenkins PJ. The GH-IGF-I axis and breast cancer. Trends Endocrinol Metab. 2003;14:28–34. [PubMed] [Google Scholar] Pollak M. Insulin and insulin-like growth factor signalling in neoplasia. Nat Rev Cancer. 2008;8:915–928. [PubMed] [Google Scholar] Mayo KE. A little lesson in growth regulation. Nat Genet. 1996;12:8–9. [PubMed] [Google Scholar] Rosenfeld RG, Rosenbloom AL, Guevara-Aguirre J. Growth hormone (GH) insensitivity due to primary GH receptor deficiency. Endocr Rev. 1994;15:369–390. [PubMed] [Google Scholar] Goddard AD, Covello R, Luoh SM, Clackson T, Attie KM, Gesundheit N, Rundle AC, Wells JA, Carlsson LM. Mutations of the growth hormone receptor in children with idiopathic short stature. The Growth Hormone Insensitivity Study Group. N Engl J Med. 1995;333:1093–1098. [PubMed] [Google Scholar] Abuzzahab MJ, Schneider A, Goddard A, Grigorescu F, Lautier C, Keller E, Kiess W, Klammt J, Kratzsch J, Osgood D, Pfaffle R, Raile K, Seidel B, Smith RJ, Chernausek SD. IGF-I receptor mutations resulting in intrauterine and postnatal growth retardation. N Engl J Med. 2003;349:2211–2222. [PubMed] [Google Scholar] Woods KA, Camacho-Hubner C, Savage MO, Clark AJ. Intrauterine growth retardation and postnatal growth failure associated with deletion of the insulin-like growth factor I gene. N Engl J Med. 1996;335:1363–1367. [PubMed] [Google Scholar] Lupu F, Terwilliger JD, Lee K, Segre GV, Efstratiadis A. Roles of growth hormone and insulin-like growth factor 1 in mouse postnatal growth. Dev Biol. 2001;229:141–162. [PubMed] [Google Scholar] Powell-Braxton L, Hollingshead P, Warburton C, Dowd M, Pitts-Meek S, Dalton D, Gillett N, Stewart TA. IGF-I is required for normal embryonic growth in mice. Genes Dev. 1993;7:2609–2617. [PubMed] [Google Scholar] Sotiropoulos A, Ohanna M, Kedzia C, Menon RK, Kopchick JJ, Kelly PA, Pende M. Growth hormone promotes skeletal muscle cell fusion independent of insulin-like growth factor 1 up-regulation. Proc Natl Acad Sci U S A. 2006;103:7315–7320. [PMC free article] [PubMed] [Google Scholar] Fernandez AM, Dupont J, Farrar RP, Lee S, Stannard B, Le Roith D. Muscle-specific inactivation of the IGF-I receptor induces compensatory hyperplasia in skeletal muscle. J Clin Invest. 2002;109:347–355. [PMC free article] [PubMed] [Google Scholar] Coleman ME, DeMayo F, Yin KC, Lee HM, Geske R, Montgomery C, Schwartz RJ. Myogenic vector expression of insulin-like growth factor I stimulates muscle cell differentiation and myofiber hypertrophy in transgenic mice. J Biol Chem. 1995;270:12109–12116. [PubMed] [Google Scholar] Barton-Davis ER, Shoturma DI, Musaro A, Rosenthal N, Sweeney HL. Viral mediated expression of insulin-like growth factor I blocks the aging-related loss of skeletal muscle function. Proc Natl Acad Sci U S A. 1998;95:15603–15607. [PMC free article] [PubMed] [Google Scholar] Bodine SC, Stitt TN, Gonzalez M, Kline WO, Stover GL, Bauerlein R, Zlotchenko E, Scrimgeour A, Lawrence JC, Glass DJ, Yancopoulos GD. Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo. Nat Cell Biol. 2001;3:1014–1019. [PubMed] [Google Scholar] Musaro A, McCullagh K, Paul A, Houghton L, Dobrowolny G, Molinaro M, Barton ER, Sweeney HL, Rosenthal N. Localized Igf-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle. Nat Genet. 2001;27:195–200. [PubMed] [Google Scholar] Barton ER, Morris L, Musaro A, Rosenthal N, Sweeney HL. Muscle-specific expression of insulin-like growth factor I counters muscle decline in mdx mice. J Cell Biol. 2002;157:137– 148. [PMC free article] [PubMed] [Google Scholar] Caroni P, Schneider C. Signaling by insulin-like growth factors in paralyzed skeletal muscle: rapid induction of IGF1 expression in muscle fibers and prevention of interstitial cell proliferation by IGF-BP5 and IGF-BP4. J Neurosci. 1994;14:3378–3388. [PMC free article] [PubMed] [Google Scholar] Edwall D, Schalling M, Jennische E, Norstedt G. Induction of insulin-like growth factor I messenger ribonucleic acid during regeneration of rat skeletal muscle. Endocrinology. 1989;124:820–825. [PubMed] [Google Scholar] DeVol DL, Rotwein P, Sadow JL, Novakofski J, Bechtel PJ. Activation of insulin-like growth factor gene expression during work-induced skeletal muscle growth. Am J Physiol. 1990;259:E89–E95. [PubMed] [Google Scholar] Carson JA, Nettleton D, Reecy JM. Differential gene expression in the rat soleus muscle during early work overload-induced hypertrophy. FASEB J. 2002;16:207–209. [PubMed] [Google Scholar] Waters MJ, Hoang HN, Fairlie DP, Pelekanos RA, Brown RJ. New insights into growth hormone action. J Mol Endocrinol. 2006;36:1–7. [PubMed] [Google Scholar] Herrington J, Carter-Su C. Signaling pathways activated by the growth hormone receptor. Trends Endocrinol Metab. 2001;12:252–257. [PubMed] [Google Scholar] Lanning NJ, Carter-Su C. Recent advances in growth hormone signaling. Rev Endocr Metab Disord. 2006;7:225–235. [PubMed] [Google Scholar] Rotwein P, Thomas MJ, Harris DM, Gronowski AM, LeStunff C. Nuclear actions of growth hormone: an in vivo perspective. J Anim Sci. 1997;75:11–19. [Google Scholar] Herrington J, Smit LS, Schwartz J, Carter-Su C. The role of STAT proteins in growth hormone signaling. Oncogene. 2000;19:2585–2597. [PubMed] [Google Scholar] Levy DE, Darnell JEJ. Stats: transcriptional control and biological impact. Nat Rev Mol Cell Biol. 2002;3:651–662. [PubMed] [Google Scholar] Gronowski AM, Rotwein P. Rapid changes in nuclear protein tyrosine phosphorylation after growth hormone treatment in vivo. Identification of phosphorylated mitogen-activated protein kinase and STAT91. J Biol Chem. 1994;269:7874–7878. [PubMed] [Google Scholar] Gronowski AM, Zhong Z, Wen Z, Thomas MJ, Darnell JEJ, Rotwein P. In vivo growth hormone treatment rapidly stimulates the tyrosine phosphorylation and activation of Stat3. Mol Endocrinol. 1995;9:171–177. [PubMed] [Google Scholar] Ram PA, Park SH, Choi HK, Waxman DJ. Growth hormone activation of Stat 1, Stat 3, and Stat 5 in rat liver. Differential kinetics of hormone desensitization and growth hormone stimulation of both tyrosine phosphorylation and serine/threonine phosphorylation. J Biol Chem. 1996;271:5929–5940. [PubMed] [Google Scholar] Campbell GS, Meyer DJ, Raz R, Levy DE, Schwartz J, Carter-Su C. Activation of acute phase response factor (APRF)/Stat3 transcription factor by growth hormone. J Biol Chem. 1995;270:3974–3979. [PubMed] [Google Scholar] Smit LS, Vanderkuur JA, Stimage A, Han Y, Luo G, Yu-Lee LY, Schwartz J, Carter-Su C. Growth hormone-induced tyrosyl phosphorylation and deoxyribonucleic acid binding activity of Stat5A and Stat5B. Endocrinology. 1997;138:3426–3434. [PubMed] [Google Scholar] Smit LS, Meyer DJ, Billestrup N, Norstedt G, Schwartz J, Carter-Su C. The role of the growth hormone (GH) receptor and JAK1 and JAK2 kinases in the activation of Stats 1, 3, and 5 by GH. Mol Endocrinol. 1996;10:519–533. [PubMed] [Google Scholar] Gebert CA, Park SH, Waxman DJ. Regulation of signal transducer and activator of transcription (STAT) 5b activation by the temporal pattern of growth hormone stimulation. Mol Endocrinol. 1997;11:400–414. [PubMed] [Google Scholar] Teglund S, McKay C, Schuetz E, van Deursen JM, Stravopodis D, Wang D, Brown M, Bodner S, Grosveld G, Ihle JN. Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses. Cell. 1998;93:841–850. [PubMed] [Google Scholar] Udy GB, Towers RP, Snell RG, Wilkins RJ, Park SH, Ram PA, Waxman DJ, Davey HW. Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression. Proc Natl Acad Sci U S A. 1997;94:7239–7244. [PMC free article] [PubMed] [Google Scholar] Kofoed EM, Hwa V, Little B, Woods KA, Buckway CK, Tsubaki J, Pratt KL, Bezrodnik L, Jasper H, Tepper A, Heinrich JJ, Rosenfeld RG. Growth hormone insensitivity associated with a STAT5b mutation. N Engl J Med. 2003;349:1139–1147. [PubMed] [Google Scholar] Hwa V, Little B, Adiyaman P, Kofoed EM, Pratt KL, Ocal G, Berberoglu M, Rosenfeld RG. Severe growth hormone insensitivity resulting from total absence of signal transducer and activator of transcription 5b. J Clin Endocrinol Metab. 2005;90:4260–4266. [PubMed] [Google Scholar] Rosenfeld RG, Belgorosky A, Camacho-Hubner C, Savage MO, Wit JM, Hwa V. Defects in growth hormone receptor signaling. Trends Endocrinol Metab. 2007;18:134–141. [PubMed] [Google Scholar] Thompson BJ, Shang CA, Waters MJ. Identification of genes induced by growth hormone in rat liver using cDNA arrays. Endocrinology. 2000;141:4321–4324. [PubMed] [Google Scholar] Flores-Morales A, Stahlberg N, Tollet-Egnell P, Lundeberg J, Malek RL, Quackenbush J, Lee NH, Norstedt G. Microarray analysis of the in vivo effects of hypophysectomy and growth hormone treatment on gene expression in the rat. Endocrinology. 2001;142:3163–3176. [PubMed] [Google Scholar] Rowland JE, Lichanska AM, Kerr LM, White M, d'Aniello EM, Maher SL, Brown R, Teasdale RD, Noakes PG, Waters MJ. In vivo analysis of growth hormone receptor signaling domains and their associated transcripts. Mol Cell Biol. 2005;25:66–77. [PMC free article] [PubMed] [Google Scholar] Huo JS, McEachin RC, Cui TX, Duggal NK, Hai T, States DJ, Schwartz J. Profiles of growth hormone (GH)-regulated genes reveal time-dependent responses and identify a mechanism for regulation of activating transcription factor 3 by GH. J Biol Chem. 2006;281:4132–4141. [PubMed] [Google Scholar] Vidal OM, Merino R, Rico-Bautista E, Fernandez-Perez L, Chia DJ, Woelfle J, Ono M, Lenhard B, Norstedt G, Rotwein P, Flores-Morales A. In vivo transcript profiling and phylogenetic analysis identifies suppressor of cytokine signaling 2 as a direct signal transducer and activator of transcription 5b target in liver. Mol Endocrinol. 2007;21:293–311. [PubMed] [Google Scholar] Clodfelter KH, Holloway MG, Hodor P, Park SH, Ray WJ, Waxman DJ. Sex-dependent liver gene expression is extensive and largely dependent upon signal transducer and activator of transcription 5b (STAT5b): STAT5b-dependent activation of male genes and repression of female genes revealed by microarray analysis. Mol Endocrinol. 2006;20:1333–1351. [PubMed] [Google Scholar] Jorgensen JO, Jessen N, Pedersen SB, Vestergaard E, Gormsen L, Lund SA, Billestrup N. GH receptor signaling in skeletal muscle and adipose tissue in human subjects following exposure to an intravenous GH bolus. Am J Physiol Endocrinol Metab. 2006;291:E899–E905. [PubMed] [Google Scholar] Nielsen C, Gormsen LC, Jessen N, Pedersen SB, Moller N, Lund S, Jorgensen JO. Growth hormone signaling in vivo in human muscle and adipose tissue: impact of insulin, substrate background, and growth hormone receptor blockade. J Clin Endocrinol Metab. 2008;93:2842–2850. [PubMed] [Google Scholar] Waxman DJ, O'Connor C. Growth hormone regulation of sex-dependent liver gene expression. Mol Endocrinol. 2006;20:2613–2629. [PubMed] [Google Scholar] Wauthier V, Waxman DJ. Sex-specific early growth hormone response genes in rat liver. Mol Endocrinol. 2008;22:1962–1974. [PMC free article] [PubMed] [Google Scholar] Ahluwalia A, Clodfelter KH, Waxman DJ. Sexual dimorphism of rat liver gene expression: regulatory role of growth hormone revealed by deoxyribonucleic Acid microarray analysis. Mol Endocrinol. 2004;18:747–760. [PubMed] [Google Scholar] Zhou YC, Waxman DJ. Cross-talk between janus kinase-signal transducer and activator of transcription (JAK-STAT) and peroxisome proliferator-activated receptor-alpha (PPARalpha) signaling pathways. Growth hormone inhibition of pparalpha transcriptional activity mediated by stat5b. J Biol Chem. 1999;274:2672–2681. [PubMed] [Google Scholar] Zhou YC, Waxman DJ. STAT5b down-regulates peroxisome proliferator-activated receptor alpha transcription by inhibition of ligand-independent activation function region-1 transactivation domain. J Biol Chem. 1999;274:29874–29882. [PubMed] [Google Scholar] Ono M, Chia DJ, Merino-Martinez R, Flores-Morales A, Unterman TG, Rotwein P. Signal transducer and activator of transcription (Stat) 5b-mediated inhibition of insulin-like growth factor binding protein-1 gene transcription: a mechanism for repression of gene expression by growth hormone. Mol Endocrinol. 2007;21:1443–1457. [PubMed] [Google Scholar] Murphy LJ. Insulin-like growth factor-binding proteins: functional diversity or redundancy? J Mol Endocrinol. 1998;21:97–107. [PubMed] [Google Scholar] Barthel A, Schmoll D, Unterman TG. FoxO proteins in insulin action and metabolism. Trends Endocrinol Metab. 2005;16:183–189. [PubMed] [Google Scholar] Accili D, Arden KC. FoxOs at the crossroads of cellular metabolism, differentiation, and transformation. Cell. 2004;117:421–426. [PubMed] [Google Scholar] Rotwein P. Contemporary endocrinology: the IGF system. Totowa: Humana Press; 1999. Molecular biology of IGF-I and IGF-II; pp. 19–35. [Google Scholar] Hall LJ, Kajimoto Y, Bichell D, Kim SW, James PL, Counts D, Nixon LJ, Tobin G, Rotwein P. Functional analysis of the rat insulin-like growth factor I gene and identification of an IGF-I gene promoter. DNA Cell Biol. 1992;11:301–313. [PubMed] [Google Scholar] Adamo ML, Ben-Hur H, Roberts CTJ, LeRoith D. Regulation of start site usage in the leader exons of the rat insulin-like growth factor-I gene by development, fasting, and diabetes. Mol Endocrinol. 1991;5:1677–1686. [PubMed] [Google Scholar] Shimatsu A, Rotwein P. Mosaic evolution of the insulin-like growth factors. Organization, sequence, and expression of the rat insulin-like growth factor I gene. J Biol Chem. 1987;262:7894–7900. [PubMed] [Google Scholar] Kim SW, Lajara R, Rotwein P. Structure and function of a human insulin-like growth factor-I gene promoter. Mol Endocrinol. 1991;5:1964–1972. [PubMed] [Google Scholar] Kavsan VM, Koval AP, Grebenjuk VA, Chan SJ, Steiner DF, Roberts CTJ, LeRoith D. Structure of the chum salmon insulin-like growth factor I gene. DNA Cell Biol. 1993;12:729–737. [PubMed] [Google Scholar] Hoyt EC, Van Wyk JJ, Lund PK. Tissue and development specific regulation of a complex family of rat insulin-like growth factor I messenger ribonucleic acids. Mol Endocrinol. 1988;2:1077–1086. [PubMed] [Google Scholar] Woelfle J, Billiard J, Rotwein P. Acute control of insulin-like growth factor-1 gene transcription by growth hormone through STAT5B. J Biol Chem. 2003;278:22696–22702. [PubMed] [Google Scholar] Woelfle J, Chia DJ, Rotwein P. Mechanisms of growth hormone (GH) action. Identification of conserved Stat5 binding sites that mediate GH-induced insulin-like growth factor-I gene activation. J Biol Chem. 2003;278:51261–51266. [PubMed] [Google Scholar] Bichell DP, Kikuchi K, Rotwein P. Growth hormone rapidly activates insulin-like growth factor I gene transcription in vivo. Mol Endocrinol. 1992;6:1899–1908. [PubMed] [Google Scholar] Thomas MJ, Kikuchi K, Bichell DP, Rotwein P. Characterization of deoxyribonucleic acid-protein interactions at a growth hormone-inducible nuclease hypersensitive site in the rat insulin-like growth factor-I gene. Endocrinology. 1995;136:562–569. [PubMed] [Google Scholar] An MR, Lowe WLJ. The major promoter of the rat insulin-like growth factor-I gene binds a protein complex that is required for basal expression. Mol Cell Endocrinol. 1995;114:77–89. [PubMed] [Google Scholar] Mittanck DW, Kim SW, Rotwein P. Essential promoter elements are located within the 5' untranslated region of human insulin-like growth factor-I exon I. Mol Cell Endocrinol. 1997;126:153–163. [PubMed] [Google Scholar] Wang L,Wang X, Adamo ML. Two putative GATA motifs in the proximal exon 1 promoter of the rat insulin-like growth factor I gene regulate basal promoter activity. Endocrinology. 2000;141:1118–1126. [PubMed] [Google Scholar] Wang X, Talamantez JL, Adamo ML. A CACCC box in the proximal exon 2 promoter of the rat insulin-like growth factor I gene is required for basal promoter activity. Endocrinology. 1998;139:1054–1066. [PubMed] [Google Scholar] Wang Y, Jiang H. Identification of a distal STAT5-binding DNA region that may mediate growth hormone regulation of insulin-like growth factor-I gene expression. J Biol Chem. 2005;280:10955–10963. [PubMed] [Google Scholar] Chia DJ, Ono M, Woelfle J, Schlesinger-Massart M, Jiang H, Rotwein P. Characterization of distinct Stat5b binding sites that mediate growth hormone-stimulated IGF-I gene transcription. J Biol Chem. 2006;281:3190–3197. [PubMed] [Google Scholar] Eleswarapu S, Gu Z, Jiang H. Growth hormone regulation of insulin-like growth factor-I gene expression may be mediated by multiple distal signal transducer and activator of transcription 5 binding sites. Endocrinology. 2008;149:2230–2240. [PMC free article] [PubMed] [Google Scholar] Björntorp, P. (1992) Biochemistry of obesity in relation to diabetes. In: KGMM Alberti RA DeFronzo H Keen P Zimmet eds. International Textbook of Diabetes Mellitus 551– 568. John Wiley & Sons Ltd London, United Kingdom. Google Scholar  Björntorp, P. (1992) Hormonal effects on fat distribution and its relationship to health risk factors. Acta Paediatr Suppl 383: 59– 60. CAS PubMed Google Scholar  Rosèn, T., Bosaeus, I., Tolli, J., Lindstedt, G., Bengtsson, BA. (1993) Increased body fat mass and decreased extracellular fluid volume in adults with growth hormone deficiency. Clin Endocrinol (Oxf) 38: 63 Wiley Online Library PubMed Web of Science®Google Scholar  Liu JP, Baker J, Perkins AS, Robertson EJ, Efstratiadis A. Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r) Cell. 1993;75:59–72. [PubMed] [Google Scholar] Zhou Y, Xu BC, Maheshwari HG, He L, Reed M, Lozykowski M, Okada S, Cataldo L, Coschigamo K, Wagner TE, Baumann G, Kopchick JJ. A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse) Proc Natl Acad Sci U S A. 1997;94:13215–13220. [PMC free article] [PubMed] [Google Scholar] Sims NA, Clement-Lacroix P, Da Ponte F, Bouali Y, Binart N, Moriggl R, Goffin V, Coschigano K, Gaillard-Kelly M, Kopchick J, Baron R, Kelly PA. Bone homeostasis in growth hormone receptor-null mice is restored by IGF-I but independent of Stat5. J Clin Invest. 2000;106:1095–1103. [PMC free article] [PubMed] [Google Scholar] Yakar S, Rosen CJ, Beamer WG, Ackert-Bicknell CL, Wu Y, Liu JL, Ooi GT, Setser J, Frystyk J, Boisclair YR, LeRoith D. Circulating levels of IGF-1 directly regulate bone growth and density. J Clin Invest. 2002;110:771–781. [PMC free article] [PubMed] [Google Scholar] Miyakoshi N, Kasukawa Y, Linkhart TA, Baylink DJ, Mohan S. Evidence that anabolic effects of PTH on bone require IGF-I in growing mice. Endocrinology. 2001;142:4349–4356. [PubMed] [Google Scholar] Neer RM, Arnaud CD, Zanchetta JR, Prince R, Gaich GA, Reginster JY, Hodsman AB, Eriksen EF, Ish-Shalom S, Genant HK, Wang O, Mitlak BH. Effect of parathyroid hormone (1–34) on fractures and bone mineral density in postmenopausal women with osteoporosis. N Engl J Med. 2001;344:1434–1441. [PubMed] [Google Scholar] Ishizuya T, Yokose S, Hori M, Noda T, Suda T, Yoshiki S, Yamaguchi A. Parathyroid hormone exerts disparate effects on osteoblast differentiation depending on exposure time in rat osteoblastic cells. J Clin Invest. 1997;99:2961–2970. [PMC free article] [PubMed] [Google Scholar] McCarthy TL, Centrella M, Canalis E. Parathyroid hormone enhances the transcript and polypeptide levels of insulin-like growth factor I in osteoblast-enriched cultures from fetal rat bone. Endocrinology. 1989;124:1247–1253. [PubMed] [Google Scholar] Zhao G, Monier-Faugere MC, Langub MC, Geng Z, Nakayama T, Pike JW, Chernausek SD, Rosen CJ, Donahue LR, Malluche HH, Fagin JA, Clemens TL. Targeted overexpression of insulin-like growth factor I to osteoblasts of transgenic mice: increased trabecular bone volume without increased osteoblast proliferation. Endocrinology. 2000;141:2674–2682. [PubMed] [Google Scholar] Bengtsson, BÅ, Edén, S., Lönn, L., et al (1993) Treatment of adults with growth hormone (GH) deficiency with recombinant human GH. J Clin Endocrinol Metab 76: 309– 317. Crossref CAS PubMed Web of Science®Google Scholar  Al‐Shoumer, K. A. S., Page, B., Thomas, E., Murphy, M., Beshyah, S. A., Johnston, DG. (1996) Effects of four years’ treatment with biosynthetic human growth hormone (GH) on body composition in GH‐deficient hypopituitary adults. Eur Endocrinol 135: 559– 567. Crossref CAS PubMed Web of Science®Google Scholar  Li, C. H., Simpson, M. E., Evans, HM. (1949) Influence of growth and adrenocorticotropic hormone on the body composition of hypophysectomized rats. Endocrinology 44: 71– 75. Crossref CAS PubMed Web of Science®Google Scholar  Scow, RO. (1959) Effects of growth hormone and thyroxine on growth and chemical composition of muscle, bone and other tissues in thyroidectomized‐hypophysectomized rats. Am J Physiol 196: 859– 865. CAS PubMed Web of Science®Google Scholar  Lee, M. O., Schaffer, NK. (1934) Anterior pituitary growth hormone and the composition of growth. J Nutr 7: 337– 363. Crossref CAS Web of Science®Google Scholar  Goodman, H. M., Schwartz, J. (1974) Growth hormone and lipid metabolism. In: E Enobil WH Sawyer eds. Handbook of Physiology, Part 2 IV: 211– 232. American Physiological Society Washington DC. Google Scholar  Bengtsson, BÅ, Brummer, R. J. M., Edén, S., Rosèn, T., Sjöström, L. (1992) Effects of growth hormone on fat mass and fat distribution. Acta Paediatr Suppl 383: 62– 65. PubMed Google Scholar  Tanner, J. M., Hughes, P. C. R., Whitehouse, RH. (1977) Comparative rapidity of response of height, limb muscle and limb fat to treatment with human growth hormone in patients with and without growth hormone deficiency. Acta Endocrinol (Copenh) 84: 53– 57. Google Scholar  Goodman, H. M., Gorin, E., Honeyman, TW. (1988) Biochemical basis for the lipolytic activity of growth hormone. In: LE Underwood eds. Human Growth Hormone: Progress and Challenges 75– 111. Marcel Dekker Inc New York. Google Scholar  Bonnet, F., Vanderschueren‐Lodeweyckx, M., Echels, R., Malvaux, P. (1974) Subcutaneous adipose tissue and lipids in blood in growth hormone deficiency before and after treatment with human growth hormone. Pediatr Res 8: 800– 805. Crossref CAS PubMed Web of Science®Google Scholar  van Vliet, G, Bosson, D., Craen, M., Caju, NVLD, Malvaux, P., Vanderschueren‐Lodeweyckx, M. (1987) Comparative study of the lipolytic potencies of pituitary‐derived and biosynthetic human growth hormone in hypopituitary children. J Clin Endocrinol Metab 65: 876– 879. Crossref PubMed Web of Science®Google Scholar  Beauville, M., Harent, I., Crampes, F., Riviere, D., Tauber, M. T., Tauber, J. P., Garrigues, M. (1992) Effect of long‐term rhGH administration in GH‐deficient adults on fat cell epinephrine response. Am J Physiol 263: E467– E472. Crossref CAS PubMed Web of Science®Google Scholar  Vernon, R. G., Flint, DJ. (1989) Role of growth hormone in the regulation of adipocyte growth and function. In: RB Heap, C Prosser GE Lamming eds. Biotechnology in Growth Regulation 57– 71. Butterworths London, United Kingdom. Crossref Web of Science®Google Scholar  Harant, I., Beauville, M., Crampes, F., et al (1994) Response of fat cells to growth hormone (GH): effect of long term treatment with recombinant human GH in GH‐deficient adults. J Clin Endocrinol Metab 78: 1392– 1395. Crossref PubMed Web of Science®Google Scholar  Marcus, C., Bolme, P., Micha‐Johansson, G., Margery, V., Brönnegård, M. (1994) Growth hormone increases the lipolytic sensitivity from catecholamines in adipocytes from healthy adults. Life Sci 54: 1335– 1341. Crossref CAS PubMed Web of Science®Google Scholar  Yang, S., Björntorp, P., Liu, X., Edén, S. (1996) Growth hormone treatment of hypophysectomized rats increases catecholamine‐induced lipolysis and the number of β‐adrenergic receptors in adipocytes: no differences in the effects of growth hormone on different fat depots. Obes Res 4: 471– 478. Wiley Online Library CAS PubMed Web of Science®Google Scholar  Watt, P. W., Finley, E., Cork, S., Legg, R. A., Vernon, RG. (1991) Chronic control of the β‐ and α2‐adrenergic systems of sheep adipose tissue by growth hormone and insulin. Biochem J 273: 39– 42. Crossref CAS PubMed Web of Science®Google Scholar  Arner, P. (1992) Adrenergic receptor function in fat cells. Am J Clin Nutr 55: 228S– 236S. Crossref CAS PubMed Web of Science®Google Scholar  Arner, P., Hellmér, J., Wennlund, A., Östman, J., Engfeldt, P. (1988) Adrenoceptor occupancy in isolated human fat cells and its relationship with lipolysis rate. Eur J Pharmacol 146: 45– 56. Crossref CAS PubMed Web of Science®Google Scholar  Davidson, MB. (1987) Effect of growth hormone on carbohydrate and lipid metabolism. Endocr Rev 8: 115– 131. Crossref CAS PubMed Web of Science®Google Scholar  Ottosson, M., Lönnroth, P., Björntorp, Edén S. (2000) Effects of cortisol and growth hormone on lipolysis in human adipose tissue. J Clin Endocrinol Metab 85: 799– 803. Crossref CAS PubMed Web of Science®Google Scholar  Pierlussi, J., Pierlussi, R., Aschcroft, SJH. (1980) Effects of growth hormone on insulin release in the rat. Diabetologia 19: 391– 396. Crossref PubMed Web of Science®Google Scholar  Roupas, P., Ghou, S. T., Towns, R. J., Kostyo, JL. (1991) Growth hormone inhibits activation of phosphatidylinositol phospholipase C in adipose plasma membranes: evidence for a growth hormone‐induced change in G protein function. Physiol Pharmacol 88: 1691– 1695. CAS PubMed Web of Science®Google Scholar  72 Slavin, B. G., Ong, J. M., Kern, P. (1994) Hormonal regulation of hormone‐sensitive lipase activity and mRNA levels in isolated rat adiposities. J Lipid Res 35: 1535– 1541. CAS PubMed Web of Science®Google Scholar  Sheridan, MK. (1986) Effects of thyroxin, cortisol, growth hormone, and prolactin on lipid metabolism of coho salmon, oncorhynchus kisutch, during smoltification. Gen Comp Endocrinol 64: 220– 238. Crossref CAS PubMed Web of Science®Google Scholar  Dietz, J., Schwartz, J. (1991) Microdetermination of long chain fatty acids in plasma and tissue. J Biol Chem 235: 2595– 2599. PubMed Web of Science®Google Scholar Yang, S., Xu, X., Björntorp, P., Edén, S. (1995) Additive effects of growth hormone and testosterone on lipolysis in adipocytes of hypophysectomized rats. J Endocrinol 147: 147– 152. Crossref CAS PubMed Web of Science®Google Scholar  Lands, A. M., Arnold, A., McAuliff, J. P., Bron, TG. (1967) Differentiation of receptor systems activated by sympathetic amines. Nature 214: 597– 598. Crossref CAS PubMed Web of Science®Google Scholar  Stiles, G. L., Caron, M. G., Lefkowitz, RJ. (1984) β‐Adrenergic receptors: biochemical mechanisms of physiological regulation. Physiol Rev 64: 661– 743. Crossref CAS PubMed Web of Science®Google Scholar  Emorine, L. J., Marullo, S., Briend‐Sutren, M. M., et al (1989) Molecular characterization of human β3‐adrenergic receptor. Science 245: 1118– 1121. Crossref CAS PubMed Web of Science®Google Scholar  Ahquist, RP. (1948) A study of the adrenotropic receptors. Am J Physiol 153: 586– 600. PubMed Web of Science®Google Scholar  Honnor, R. C., Dhillon, G. S., Londos, C. (1985) cAMP‐dependent protein kinase and lipolysis in rat adipocytes. I. Cell preparation, manipulation and predictability in behavior. J Biol Chem 260: 15122– 15129. CAS PubMed Web of Science®Google Scholar  Honnor, R. C., Dhillon, G. S., Londos, C. (1985) cAMP‐dependent protein kinase and lipolysis in rat adipocytes. II. Definition of steady‐state relationship with lipolytic and antilipolytic modulators. J Biol Chem 260: 15130– 15138. CAS PubMed Web of Science®Google Scholar  Corbin, J. D., Cobb, C. E., Beebe, S. J., et al (1988) Mechanism and function of cAMP‐ and cGMP‐dependent protein kinases. Adv Second Messenger Phosphoprotein Res 21: 75– 86. CAS PubMed Web of Science®Google Scholar  Londos, C., Brasaemle, D. L., Schultz, C. J., Segrest, J. P., Kimmel, AR. (1999) Perilipins, ADRP, and other proteins that associate with intracellular neutral lipid droplets in animal cells. Semin Cell Dev Biol 10: 51– 58. Crossref CAS PubMed Web of Science®Google Scholar  Holm, C., Osterlund, T., Laurell, H., Contreras, JA. (2000) Molecular mechanisms regulating hormone‐sensitive lipase and lipolysis. Annu Rev Nutr 20: 365– 393. Crossref CAS PubMed Web of Science®Google Scholar  Brasaemle, D. L., Rubin, B., Harten, I. A., Gruia‐Gray, J., Kimmel, A. R., Londos, C. (2000) Perilipin A increases triacylglycerol storage by decreasing the rate of triacylglycerol hydrolysis. J Biol Chem 275: 38486– 38493. Crossref CAS PubMed Web of Science®Google Scholar  Tansey, J. T., Huml, A. M., Vogt, R., et al (2003) Functional studies on native and mutated forms of perilipins. A role in protein kinase A‐mediated lipolysis of triacylglycerols. J Biol Chem 278: 8401– 8406. Crossref CAS PubMed Web of Science®Google Scholar  Strålfors, P., Björgell, P., Belfrage, P. (1984) Hormone regulation of hormone‐sensitive lipase in intact adipocytes: Identification of phosphorylated sites and effects of the phosphorylation by lipolytic hormone and insulin. Proc Natl Acad Sci U S A 81: 3317– 3321. Crossref CAS PubMed Web of Science®Google Scholar  Egan, J. J., Greenberg, A. S., Chang, M. K., Wek, SA Moos JMC, Londos, C. (1992) Mechanism of hormone‐stimulated lipolysis in adipocytes: translocation of hormone‐sensitive lipase to the lipid storage droplet. Proc Natl Acad Sci U S A 89: 8537– 8541. Crossref CAS PubMed Web of Science®Google Scholar  Anthonsen, M. W., Ronnstrand, L., Wernstedt, C., Degerman, E., Holm, C. (1998) Identification of novel phosphorylation sites in hormone‐sensitive lipase that are phosphorylated in response to isoproterenol and govern activation properties in vitro. J Biol Chem 273: 215– 221. Crossref CAS PubMed Web of Science®Google Scholar  Sztalryd, C., Xu, G., Dorward, H., et al (2003) Perilipin A is essential for the translocation of hormone‐sensitive lipase during lipolytic activation. J Cell Boil 161: 1093– 1103. Crossref CAS PubMed Web of Science®Google Scholar  Smith, PE. (1930) Hypophysectomy and replacement therapy in the rat. Am J Anat 45: 205– 273. Wiley Online Library Web of Science®Google Scholar  Edén, S., Jansson, J. O., Oscarsson, J. (1987) Sexual dimorphism of growth hormone secretion. In: O Isaksson C Binder K Hall B Hökfelt eds. Growth Hormone—Basic and Clinical Aspects 129– 151. Elsevier Science Publishers B.V Amsterdam. Google Scholar  Frohman, L. A., Bernardis, LL. (1970) Growth hormone secretion in rat: metabolic clearance and secretion rates. Endocrinology 86: 305– 312. Crossref CAS PubMed Google Scholar  Jansson, J. O., Albertsson‐Wikaland, K., Edén, S., Thorngren, K. G., Isaksson, O. (1982) Circumstantial evidence for a role of the secretory pattern of growth hormone in control of body growth. Acta Endocrinol 99: 24– 30. CAS PubMed Web of Science®Google Scholar  Björntorp, P., Karlsson, M., Pertoft, H., Pettersson, P., Sjöström, L., Smith, U. (1978) Isolation and characterization of cells from rat adipose tissue developing into adipocytes. J Lipid Res 19: 316– 324. CAS PubMed Web of Science®Google Scholar  Lowry, O. H., Rosebrough, N. J., Farr, A. L., Randall, RJ. (1951) Protein measurements with the folin phenol reagent. J Biol Chem 193: 265– 275. CAS PubMed Web of Science®Google Scholar  Rebuffé‐Scrive, M. (1987) Sex steroid hormones and adipose tissue metabolism in adrenalectomized and ovariectomized rats. Acta Physiol Scand 129: 471– 477. Wiley Online Library CAS PubMed Web of Science®Google Scholar  Laurell, S., Tibbling, G. (1966) An enzymatic fluorometric micromethod for the determination of glycerol. Clin Chim Acta 13: 317– 322. Crossref CAS PubMed Web of Science®Google Scholar  Dole, V. P., Meinertz, H. (1960) Microdetermination of long chain fatty acids in plasma and tissues. J Biol Chem 235: 2595– 2599. CAS PubMed Web of Science®Google Scholar  Smith, U., Sjöström, L., Björntorp, P. (1972) Comparison of two methods of determining human adipose cell size. J Lipid Res 13: 822– 824. CAS PubMed Web of Science®Google Scholar  Östman, J., Arner, P., Kimura, H., Wahrenberg, H., Engfeldt, P. (1984) Influence of fasting on lipolytic response to adrenergic agonists and on adrenergic receptors in subcutaneous adipocytes. Eur J Clin Invest 14: 383– 391. Wiley Online Library PubMed Web of Science®Google Scholar  Steiner, A. L., Pagliara, A. S., Chase, L. R., Kipnis, DM. (1972) Radioimmunoassay for cyclic nucleotides. II. Adenosine 3′, 5′‐monophosphate and guanosine 3′, 5′‐monophosphate in mammalian tissues and body fluids. J Biol Chem 247: 1114– 1120. CAS PubMed Web of Science®Google Scholar  Steiner, A. L., Parker, C. W., Kipnis, DM. (1972) Radioimmunoassay for cyclic nucleotides. I. Preparation of antibodies and iodinated cyclic nucleotides. J Biol Chem 247: 1106– 1113. CAS PubMed Web of Science®Google Scholar  McKenzie, FR. (1988) Basic techniques to study G‐protein function. In: G Milligan eds. Signal Transduction—A Practical Approach, Part 2 31– 56. Oxford University Press New York. Google Scholar  Solomon, S. S., Sibley, S. D., Dismukes, J.R. (1991) Growth hormone‐enhanced lipolysis in the spontaneously diabetic BB rat. J Lab Clin Med 118: 99– 105. CAS PubMed Web of Science®Google Scholar  Nam, S. Y., Marcus, C. (2000) Growth hormone and adipocyte function in obesity. Horm Res 53: (Suppl 1), 87– 97. Crossref CAS PubMed Web of Science®Google Scholar  Bahouth, S. W., Malbon, CC. (1988) Subclassification of β‐adrenergic receptors of rat fat cells: a re‐evaluation. Mol Pharmacol 34: 318– 326. CAS PubMed Web of Science®Google Scholar  Granneman, J. G., Lahners, K. N., Chaudhry, A. (1992) Molecular cloning and expression of the rat β3‐adrenergic receptor. Mol Pharmacol 40: 895– 899. Web of Science®Google Scholar  Hollenga, C. H., Zaagsma, J. (1989) Direct evidence for the atypical nature of functional β‐adrenoceptors in rat adipocytes. Br J Pharmacol 98: 1420– 1424. Wiley Online Library CAS PubMed Web of Science®Google Scholar  Lacasa, D., Agli, B., Giudicelli, Y. (1985) Direct assessment of β‐adrenergic receptors in intact rat adipocytes by binding of [3H]CGP 12177. Eur J Biochem 146: 339– 346. Wiley Online Library CAS PubMed Web of Science®Google Scholar  Umekawa, T., Yoshida, T., Sakane, N., Kondo, M. (1996) Effect of CL316, 243, a highly specific β3‐adrenoceptor agonit, on lipolysis of human and rat adipocytes. Horm Metab Res 28: 394– 396. Crossref CAS PubMed Web of Science®Google Scholar  Bojanic, D., Nahorski, SR. (1983) Identification and subclassification of rat adipocyte β‐adrenoceptors using (±)‐[125I]cyanopindolol. Eur J Pharmacol 93: 235– 243. Crossref CAS PubMed Web of Science®Google Scholar  Langin, D., Portillo, M., Saulnier‐Blache, J. S., Lafontan, M. (1991) Coexistence of three beta‐adrenergic receptor subtypes in white fat cells of various mammalian species. Eur J Pharmacol 199: 291– 301. Crossref CAS PubMed Web of Science®Google Scholar   •••WANT YOUR QUESTION ANSWERED?••• Create a free account at www.theprepcoachforum.com and post up your question in the Mike Arnold PED Q&A open threat!    •••SUPPORT OUR PEPTIDE/RESEARCH CHEMS SPONSORS•••   (RESEARCH CHEMS) www.maresearchchems.net___use discount code “alex15” to save off your order!   (SPECIALTY SUPPS) www.masupps.com___use discount code “alex20” to save off your order!   (BEEF) www.skinnybeef.com___use discount code “alex10” to save off your order!   •••FIND THE EPISODES•••   ITUNES:https://itunes.apple.com/us/podcast/beastfitness-radios-podcast/id1065532968   LIBSYN:http://beastfitnessradio.libsyn.com   VIMEO: www.vimeo.com/theprepcoach        •••PREP COACH APPAREL•••   https://teespring.com/stores/the-prep-coach-apparel    

YWD Show #193 opens with Frank Sinatra's Witchcraft for Halloween. Amber talks about her daughter Miles being sick last week & getting ready for her filming in Atlanta.  Steve talks about hanging out with Sean - seeing Sean playing the drums for an open mic and watching the World Series together. Sean also gives his perspective about the open mic. Next we hear from our friend Paul Preston from the Movie Guys and he gives his Top 5 Horror Movies.The gang also discusses the passing of actor Sean Connery, Top 10 Halloween Songs & Would You Live In This Haunted Mansion. Last we replay for you the Induction of Mark and Brian into the Radio Hall of Fame.  LINKS: Frank Sinatra Music              

Officers of registered organisations play an important role in the running of their organisation, and they are influential drivers of good governance. It is essential that all officers have the knowledge and tools to carry out their functions and responsibilities under their organisation’s rules and the Fair Work (Registered Organisations) Act 2009 (‘the RO Act’). An induction program is a structured way of providing new officers with much of the information and support they need to be confident and productive in their role. Informing officers about their duties as an officer, like their financial responsibilities under the RO Act, can make a real difference to compliance and can deter and prevent misconduct. It is best practice for officers to be made aware of their statutory duties, and the policies and procedures of their organisation, when they take office. In our latest episode of ROCpod we discuss how induction can lift the standards of governance and contribute to a culture of voluntary compliance.

In this episode I talk about the updated research evidence on using membrane sweeping or membrane stripping for inducing labor. Is membrane sweeping effective? What are the advantages and disadvantages? Why do some providers perform membrane sweeping without asking your permission beforehand? We talk about all of this, and more, in this latest episode of the Evidence Based Birth® podcast! For more information and news about Evidence Based Birth®, visit www.ebbirth.com. Find us on Facebook (https://www.facebook.com/EvidenceBasedBirth/), Instagram (https://www.instagram.com/ebbirth/), and Pinterest (https://www.pinterest.com/ebbirth/). Ready to get involved? Check out our Professional membership (including scholarship options) (https://evidencebasedbirth.com/become-pro-member/). Find an EBB Instructor here (https://evidencebasedbirth.com/find-an-instructor-parents/), and click here (https://evidencebasedbirth.com/childbirth-class/) to learn more about the Evidence Based Birth® Childbirth Class.

In episode 101 of Kiwi Birth Tales I speak with Charlotte about the birth of her daughter Imani. In this episode we cover: - trying to fall pregnant- missed miscarriage- spontaneous conception - low level of fluids towards the end of pregnancy- induction- epidural- birth centre- breastfeeding- baby bluesCharlotte also mentions the Viva La Vulva products that she has used and loved postpartum. This episode is sponsored by Your Birth Project - the online hypnobirthing course inclusive to all types of birth giving you everything you need to prepare for your labour. Use practical comfort methods and enjoy knowing your birth partner has all the knowledge they need to support you with a specific birth partners section. Find all the information at www.yourbirthproject.com or @yourbirthproject on Instagram.

Welcome Grade 8s of 2021 — Stay calm - we've got this. John Skelton (Principal) Carryn Bukris, Adam Mawdsley, Milo Ntshanga and Shea Fourie (Grade Controllers) More information of what to expect for Grade 8 in 2021. If you have more questions, start with the school's website https://www.bryanston.com/ Music : https://JohnBartmann Visit the school's website https://www.bryanston.com/ When you're ready to #BeHeard, contact the podcast specialists at

In this episode, Yuliya shares both of her babies’ birth stories. She explains how she made the intentional choice of working with a practice of in-hospital midwives as well as hired a doula for both births, as this was the kind of birth team that she felt could help her have the kind of physiological births she hoped for.While she didn’t plan or hope to have 2 inductions, that’s how things played out given unexpected circumstances in each pregnancy of low amniotic fluid and then the pandemic. She details how she was able to cope with both medical inductions with non-pharmacological pain coping techniques using some of the techniques she knows intuitively and as a clinical psychologist as well as with the support of the team she so carefully chose.

It's Kiwi Birth Tales 100th episode!!! Proudly brought to you by Made with Love Pregnancy Journal https://shesaidyes.co.nz/product/made-with-love-pregnancy-journal/ Today I speak with Hannah Barrett about the pregnancy, birth and postpartum journey with her beautiful daughter Billie Rose Barrett. In the episode we discuss: - Obstetrician care - Planned induction- Epidural- Positive birth story - Dad delivers baby - No tearing and small grazing- Breastfeeding- Birth Care - Postpartum mental health In Hannahs episode she also mentions the following products she used on her journey- Your Birth Project, online Hypnobirthing available anytime, anywhere https://www.yourbirthproject.com/ - Viva La Vulva, postpartum healing products (NZ Made) https://www.vivalavulva.co.nz/- Haakaa Letdown pump https://www.haakaa.co.nz/collections/breast-pump-all- The Vagina Physio (@thevaginaphysio) for checks during pregnancy and post birth

For this special edition of Oncology Today, I met with Dr John Pagel from the Swedish Cancer Institute in Seattle to discuss recently published and emerging research in the front-line treatment of chronic lymphocytic leukemia. CME information and select publications here (http://www.researchtopractice.com/OncologyTodayFrontLineCLL20/).

Obstetricians and Normal Childbirth.Normalising a deviation from normal, in any field, directs the baseline off track, misleads us as to what normal is and sets us on a course that becomes very difficult to correct the further down the track we go. When we normalise trauma, we no longer see it. When we normalise bad behaviour, it becomes less apparent and when we normalise a deviation from normal physiology it confuses everyone involved. So what happens when we normalise deviating from normal physiology? When practices such as routine episiotomy (or when the vulva leading to the vaginal passageway is cut open because of a belief that that the tissues cannot or will not expand by themselves), routine induction of labour (thats when a person giving birth, overwhelmingly women, are told that their bodies will be better off being forced to go into labour rather than initiating the process of physiological labour itself), when in Australia one third of babies are born through major abdominal surgery and in some hospitals in Brazil there is an 85% cesarean section rate? What happens when a deviation from the normal physiological process of childbirth - that’s when a complex living organism separates itself from another complex living organism which has been growing inside it for ten months, what happens when this occurs? Well, we don’t know the full extent of the impacts of these deviations individually or as a whole, short term and long term. But what we do know is that much unnecessary suffering occurs along the way, for everyone involved. Even, for those that are not aware of it. In my interview with Dr Fischbein he discusses his incredible journey into becoming LA’s ONLY homebirth Obstetrician and how in a country that is leading in mechanical, managed and assisted childbirth, he practices good old fashioned sticking to the blueprint. If you have any questions about this interview or our work at PBB Media, shoot us a line at hello@pbbmedia.org.Some fun facts:> In the Netherland over 15% of babies are born at home.> In Australia 98% of women labour and birth in the hospital, 1.5% in a birth centre or on the side of the road and 0.5% at home. > In Brazil, some hospitals have an 85% Cesarean Section rate.> If you live in America or the UK and you are a black woman you are five times more likely to die during or not long after childbirth. > The US has a 31% C section rate, Australia has 34% rate (that's 1 in3!). New Zealand babies are 1 in 4 with a 25.9% rate. > 1 in 3 women in the Australia and the UK will have their labour induced.> Induction of labour for selected women giving birth for the first time in Australia in 2017 - 43.1%> 78% of Australian mothers who gave birth in 2016 had pain relief. That’s almost 4 out of 5 women. 36% of these were epidurals. > The C section rate in Finland, Iceland and Norway stay steady at around 15% (with increasing age of pregnant mothers, diabetes and other diseases). “You would never do to another mammal what you do to a human female.. no other mammal would labour like that, they would get up and run away”.Find Dr Stu here: www.birthinginstincts.comLinksWHO Statement on Cesarean Section rates: https://apps.who.int/iris/bitstream/handle/10665/161442/WHO_RHR_15.02_eng.pdf;jsessionid=FE71548F72C15166C4C9D770D1F41C11?sequence=1C Section Rates around the world (article, Belly Belly): https://www.bellybelly.com.au/birth/highest-c-section-rates-by-country/AIHW (Australian statistics on healthcare) Core Maternity Indicators: https://www.aihw.gov.au/reports/mothers-babies/ncmi-data-visualisations/contents/summaryInduction of Labour - Dr Rachel Reed (book, further links to articles and statistics): https://midwifethinking.com/2018/10/05/why-induction-matters-book-release/Produced, edited and presented by Annalee AtiaThe Pregnancy, Birth and Beyond show is part of a wider nonprofit community media and journalism project, PBB Media.All rights reserved. www.pbbmedia.orgPregnancy, Birth and Beyond comes to you from Bundjalung Country at Cavanbah or Byron Bay and we acknowledge with respect and reverence the Arakwal people of the Bunjulung nation, neighbouring clans and people for caring for this country since time immemorial.

Obstetricians and Normal Childbirth.Normalising a deviation from normal, in any field, directs the baseline off track, misleads us as to what normal is and sets us on a course that becomes very difficult to correct the further down the track we go. When we normalise trauma, we no longer see it. When we normalise bad behaviour, it becomes less apparent and when we normalise a deviation from normal physiology it confuses everyone involved. So what happens when we normalise deviating from normal physiology? When practices such as routine episiotomy (or when the vulva leading to the vaginal passageway is cut open because of a belief that that the tissues cannot or will not expand by themselves), routine induction of labour (thats when a person giving birth, overwhelmingly women, are told that their bodies will be better off being forced to go into labour rather than initiating the process of physiological labour itself), when in Australia one third of babies are born through major abdominal surgery and in some hospitals in Brazil there is an 85% cesarean section rate? What happens when a deviation from the normal physiological process of childbirth - that’s when a complex living organism separates itself from another complex living organism which has been growing inside it for ten months, what happens when this occurs? Well, we don’t know the full extent of the impacts of these deviations individually or as a whole, short term and long term. But what we do know is that much unnecessary suffering occurs along the way, for everyone involved. Even, for those that are not aware of it. In my interview with Dr Fischbein he discusses his incredible journey into becoming LA’s ONLY homebirth Obstetrician and how in a country that is leading in mechanical, managed and assisted childbirth, he practices good old fashioned sticking to the blueprint. If you have any questions about this interview or our work at PBB Media, shoot us a line at hello@pbbmedia.org.Some fun facts:> In the Netherland over 15% of babies are born at home.> In Australia 98% of women labour and birth in the hospital, 1.5% in a birth centre or on the side of the road and 0.5% at home. > In Brazil, some hospitals have an 85% Cesarean Section rate.> If you live in America or the UK and you are a black woman you are five times more likely to die during or not long after childbirth. > The US has a 31% C section rate, Australia has 34% rate (that's 1 in3!). New Zealand babies are 1 in 4 with a 25.9% rate. > 1 in 3 women in the Australia and the UK will have their labour induced.> Induction of labour for selected women giving birth for the first time in Australia in 2017 - 43.1%> 78% of Australian mothers who gave birth in 2016 had pain relief. That’s almost 4 out of 5 women. 36% of these were epidurals. > The C section rate in Finland, Iceland and Norway stay steady at around 15% (with increasing age of pregnant mothers, diabetes and other diseases). “You would never do to another mammal what you do to a human female.. no other mammal would labour like that, they would get up and run away”.Find Dr Stu here: www.birthinginstincts.comLinksWHO Statement on Cesarean Section rates: https://apps.who.int/iris/bitstream/handle/10665/161442/WHO_RHR_15.02_eng.pdf;jsessionid=FE71548F72C15166C4C9D770D1F41C11?sequence=1C Section Rates around the world (article, Belly Belly): https://www.bellybelly.com.au/birth/highest-c-section-rates-by-country/AIHW (Australian statistics on healthcare) Core Maternity Indicators: https://www.aihw.gov.au/reports/mothers-babies/ncmi-data-visualisations/contents/summaryInduction of Labour - Dr Rachel Reed (book, further links to articles and statistics): https://midwifethinking.com/2018/10/05/why-induction-matters-book-release/Produced, edited and presented by Annalee AtiaThe Pregnancy, Birth and Beyond show is part of a wider nonprofit community media and journalism project, PBB Media.All rights reserved. www.pbbmedia.orgPregnancy, Birth and Beyond comes to you from Bundjalung Country at Cavanbah or Byron Bay and we acknowledge with respect and reverence the Arakwal people of the Bunjulung nation, neighbouring clans and people for caring for this country since time immemorial.

Tit 1:5, Acts 20:28 & Various Scriptures. In the New testament we see that leaders are to be appointed to lead churches. These leadera are called Elders, Overseers & Pastors, different titles for the same office. But how many should there be? Is there a chief elder? What is their purpose? What qualifications might they […]

In Episode 98 of Kiwi Birth Tales I speak with Kate about her 2 pregnancy and birth stories. In this episode we discuss: - Scoliosis- Fertility Struggles- PCOS - Induction- Failed epidural attempts- Forcep and Episiotomy - 4th Degree Tear- Elective C-Section- Physical recoveries from birth Thank you so much for taking the time to chat with me Kate! This episode is proudly brought to you by Little One's Nappies exclusively available at Countdown. Your support of the podcast is so appreciated! To check out their awesome nappies head to https://shop.countdown.co.nz/shop/content/little-ones or to your nearest Countdown.

Following on from last week’s episode on Appliances Part 1, Rob Sinclair, of E&S Trading and Frances continue their discussion on key kitchen appliances. This episode focuses on Stove Tops and Rangehoods, plus other appliances to consider. As ever, Rob shares his incredible knowledge and practical advice about buying criteria for these appliances. SHOWNOTES: Stove tops Buying Criteria Control- Any hot plate that gives you more temperature control Whether it is gas or electric, do I have a real visible range or step of temperature Space- Creation of space and being able to fit How much space do I have at home? What are the pots I like to use, and do they fit next to each other when you are doing what you want to do? Lifestyle- What type of cooking do you use your stove top for? Induction Vs Gas Cleaning requirement- Induction stovetops are typically easier to clean than gas. Design Perspective- Induction are seamless compared to gas tops. Deliver Control- There are not as many brands available for gas that deliver a large amount of temperature control. Those available are high end products. On the other hand, induction has up to 18 different temperature settings. When it comes to high heat, induction is about twice as fast as gas will be at bringing water to boil. Flexibility- Induction has more flexibility for any cooking style. Budget- Induction starts at $1,000 Safety perspective with kids- The only thing that gets hot on an induction hot plate is the pot or the pan itself. There is no naked flame with induction, unlike gas. Additionally, pots won’t tip on an induction top because of its flat surface, unlike gas that has uneven surface. Performance and efficiency- There is a big range of both gas and induction hot plates available. Brands that offer a high quality gas stovetop are ASCO, Franke Professional and the Wolf Gas Hotplate. Highly recommended brands for Inductions are Mieli, Siemens, Neff, Smeg and AEG Range Hoods Buying Criteria Air Movement- A high quality range hood is moving air around 700-900 cubic metres per hour. Specialty brands of range hoods will do 1800 cubic metres per hour. And if you are buying a rangehood with three motors,  these  move air at 2,700 cubic meters per hour. Style of cooking- If you only do casserole then a 400-500 cubic metres per hour could work. Noise Type of range hoods- undermount, slideout, canopy Undermount Vs Slideout Vs Canopy Undermount- Integrated into the joinery across the top of your stovetop. Slideout- It is very popular in the 90’s but not necessary to increase rangehood capacity of air movement.   Canopy- Gives more an industrial  look. It gives the appearance of a commercial style kitchen. Cylinder- A  cylinder style overhead rangehood is quite popular at the moment. Brands Specialty brands develop rangehood products that suit nearly every application. Sirius- A company from Italy that makes high quality rangehoods Falmec- Another Italian Brands that specialise in rangehoods Qasair- Australian made company that has a solution like no other rangehood manufacturer. They allow custom build models to suit certain widths and applications. Cheaper alternative brands are Bosch, Miele and Smeg Ceiling cassettes and Downdraft Ventilators Creates ultimate design, particularly good for smaller spaces or when design is of utmost importance. You can have unrestricted ventilation and still have the headspace above your hot plate particularly in front of windows where there are views. Brand to consider- Bora Options for Air Sealed Homes Plasma rangehood technology- It has an activated filter that captures the fat and oils. It reduces and changes the molecular structure of fats and carbons that comes through. No odors No fats No smoke The cartridge needs to be changed about once every five years. It lasts a lot longer before they are clogged with fats and oils which makes it the more a suitable application than a mesh fiber or charcoal filtration. It also doesn’t require external ducting making it a perfect solution for air-sealed homes. However, it comes with a higher price which is about $3,000. Brand: Qasair (part of the Condari group) Other appliances for the kitchen Coffee machines- Miele have beautiful built-in and integrated coffee machines that are worth considering. Their new high end model has three different beans installed in the machine. Built-in coffee machines ranges from $4,000- $10,000. Pitt Cooktops- Glass hotplates integrated into the benchtop whether it’s reconstituted stone, natural stone or Dekton. Creates a stunning design aesthetic and continual benchtop flow. Subzero Fridges- They are an ultimate in food preservation. It filters ethylene gas which prevents vegetables and fruits to ripen easily. Subzero Fridges cost up to $17,000 or more.    Available Resources e&s TRADING Visit the E&S Website  at https://www.eands.com.au/ BEAUTIFUL KITCHEN DESIGN MADE EASY ONLINE COURSE Ready to design and create your own beautiful kitchen? Get all the interior designer insider knowledge in this online course to create your dream kitchen. Find out more and join here . BOOK A CHAT Ready to renovate or create your kitchen but not sure where to start? Get the help of a property expert and save yourself from making costly mistakes with a free Forever Home chat. Click here to get access to Frances' calendar. KITCHEN BLISS PACKAGE Overwhelmed by the amount of decisions that need to be made when creating a stylish, functional and durable kitchen? What materials to select, what colours will co-ordinate together, what design is going to best suit the space, and your requirements. We offer kitchen design packages that include joinery design and material selections for a complete kitchen design. Click the link here to find more: Related Resources: Episode 50: Kitchen Design Essentials- Kitchen Taps and Sinks Episode 49: Kitchen Design Essentials – Butler’s Pantries and Pantries Episode 47: Kitchen Design Essentials – Key Kitchen Measurements  Episode 45: Kitchen Design Essentials - Internal Elevations & Joinery Design Read our latest blog on Internal Elevations and Joinery Design here. Episode 43: Kitchen Design Essentials – Flatpack Vs Custom Designed Kitchens  Episode 41: Kitchen Design Essentials – Cabinetry Materials Episode 39: Kitchen Design Essentials – Splashbacks  Episode 38: Kitchen Design Essentials-Benchtop Criteria and Materials – Part 2 Episode 36: Kitchen Design Essentials – Benchtops part 1  Episode 14: Forever Home LIVE- Joinery Drawings and Why Do Them Early On Episode 30: Kitchen Design Essentials -Kitchen Design Layouts and Location Episode 32: Kitchen Design Essentials – The Builder’s Insight How to Choose the Right Bench Top Top 5 tips for selecting benchtops  

For this special edition of Oncology Today, I met with Dr Jeffrey Lancet from the Moffitt Cancer Center in Tampa, Florida, to discuss recently published and emerging research on induction and maintenance strategies for patients with acute myeloid leukemia. CME information and select publications here (http://www.researchtopractice.com/oncologytodayAMLInduction20).

In episode 97 of Kiwi Birth Tales I speak with Alarice who takes us through her first pregnancy and birth in Melbourne, we cover: - Unplanned pregnancy- Low Platelets- Drug free vaginal birth in hospital - Severe Mental Health concerns post partum We then discuss moving back to New Zealand and falling pregnant with her new partner but unfortunately miscarrying that pregnancy, then deciding to try again. We discuss Alarices pregnancy with Bowie and cover: - Anxiety in first trimester- Antenatal depression and taking Antidepressants during pregnancy - Polyhydramnious - Reduced fetal movements and induction- Emergency C Section under General Anaesthetic- Postpartum haemorrhage- NICU A huge thank you to this weeks sponsor - Little One's Nappies available exclusively at Countdown. https://shop.countdown.co.nz/shop/content/little-ones

Derrick Kosinki & Scott Yager induct The Miz into the Challenge Mania Hall of Fame with the help of Mark Long. The Miz gives an acceptance speech for the ages. Hear it all! Then, it's a massive 2-hour deep dive into THE GAUNTLET II and this is only part 1 of our 3 part Bonus Series. The other two parts are available at Patreon.com/ChallengeMania but you can hear Derrick (@DerrickMTV) and Scott (@SHOTOFYAGER) get into the theme, the format, the cast and the differences between The Challenge all the way back in Season 11 and today in this podcast!Attend our next LEGION OF ZOOM Call on Saturday, October 24th. Exclusive to Diesel Level Patrons and above.www.ChallengeMania.Shop is always open and the place to get We Want OGs gear, Mark Long Gear, Darrell Gear, Kam Gear, Derrick Gear, Cara Gear, Kailah Gear and MORE!www.BetterHelp.com/MANIA is giving you 10% off your first month of online counseling.

This piece tells the story of two different innovators in the field of an anesthesia. The first is, The Pediatric Device for Induction of Anesthesia (PeDIA), a mask-free anesthesia delivery system designed for kids. The second is the Error Recovery and Mitigation Aide (ERMA), a reworking of the traditional needle box whereby a clear reservoir is inserted between the re-entry proof top and opaque terminal disposal portion, allowing practitioners to have visualization of all the syringes and vials used during the course of a procedure. At the end of a single procedure, a trap door in the bottom of the reservoir is released to allow those sequestered vials and syringes to drop into the bottom of the needle box for terminal disposal. This allows providers to recognise, check and confirm possible errors in a timely fashion. Also during this piece there is a wide ranging and fascinating discussion about patents and patenting. How does the process work, how can you patent your ideas and how does the advent of block chain technology potentially change this forever? Google Patents is here: https://patents.google.com/ Check out the PeDIA website here: https://www.pediallc.com/ For more information about ERMA go here: https://ii4change.com/how-we-innovate/products/error-recovery-and-mitigation-aide/ The Facebook Group "CRNA Inventors and Innovators" mentioned in this piece is here: https://www.facebook.com/groups/2150893568464906/ This piece was part of our coverage of The American Association Nurse Anesthetists (AANA) 2019 Annual Congress in Chicago, Illinois. Check out the AANA here: https://www.aana.com/ Presented by Desiree Chappell and Monty Mythen with their guests Diane Miller, Pediatric Devices for Induction of Anesthesia | Product Development | PeDIA, LLC and Jean Snyder, CRNA Inc. Co-owner Goodwin and Snyder Anesthesia Associates, PLLC.  

The cover for issue 37 of Oncotarget features Figure 7, "The combination of romidepsin and KU60019 is synergistic in a xenograft model of MCL," by Scotto, et al. which reported that the antiproliferative effect induced by histone deactylase inhibitors is associated with the up-regulated expression of the cyclin-dependent kinase inhibitor p21. Paradoxically, the increased expression of p21 correlates with a reduced cell killing to the drug. HDAC inhibitors appear to activate p21 expression via ataxia telangiectasia mutated activity. The Oncotarget authors explored the potential synergistic interaction of the ATM inhibitor with romidepsin, given the potential complementary impact around p21. A synergistic cytotoxic effect was observed in all lymphoma cell lines examined when the HDACi was combined with KU60019. The increase in apoptosis correlates with decreased expression of p21 due to the ATM inhibitor. KU60019 decreased expression of the cyclin-dependent kinase inhibitor at the transcriptional level, compromising the ability of HDACi to induce p21 and cell cycle arrest and ultimately facilitating a shift toward the apoptotic phase. Central to the increased apoptosis observed when romidepsin is combined with KU60019 is the reduced expression of p21 and the absence of a G2/M cell cycle arrest that would be exploited by the tumor cells to evade the cytotoxic effect of the HDAC inhibitor. Dr. Owen A. O'Connor from The Columbia University Medical Center said, "HDAC inhibitors (HDACi) have emerged as valuable drugs in the treatment of select lymphomas and synergize with a diverse range of pharmacological and biological agents." The observation leads to the following hypothesis: if induction of p21 compromises the efficacy of HDAC inhibitors, then strategies to mitigate HDAC inhibitor induced p21 expression could lead to promising synergistic combinations. Induction of p21 by HDAC inhibitors is compromised in A-T cells given that ATM activity is essential for HDAC inhibitor-induced p21 expression. Collectively, these observations have led to the following hypothesis: If ATM activity is necessary for HDAC inhibitor mediated p21 induction, then selective ATM inhibitors could mitigate the HDAC induced p21 expression and potentiate its cytotoxic effect. The ATM inhibitor nullifies HDAC induction of p21 expression resulting in a synergistic interaction. KU60019 reduces p21 expression at the transcriptional level and antagonizes romidepsin transcriptional induction of p21. In both instances, the result is a markedly down-regulation of p21 expression at the protein level. The O'Connor Research Team concluded in their Oncotarget Research Paper that it is intuitive that pleotropic drugs like HDACi are likely to have both favorable and unfavorable effects on cell growth and survival. Strategies directed toward understanding how to mitigate the unfavorable influences of the class can lead to improved efficacy in rational combinations. Many examples of drug synergy with HDAC inhibitors have been driven by random efforts in mixing and matching in order to identify possible complementary partners. Obviously, a clear understanding of the molecular pharmacologic features of pleotropic drug classes like HDAC inhibitors can afford unique opportunities to think about logical combinations. Ultimately, these approaches need to be translated to the clinic in order to establish therapeutic merit in the clinic. Sign up for free Altmetric alerts about this article DOI - https://doi.org/10.18632/oncotarget.27723 Full text - https://www.oncotarget.com/article/27723/text/ Correspondence to - Owen A. O'Connor - owenaoconnor@gmail.com Keywords - lymphoma, HDAC inhibitor, ATM inhibitor, p21, cell cycle About Oncotarget Oncotarget is a weekly, peer-reviewed, open access biomedical journal covering research on all aspects of oncology. To learn more about Oncotarget, please visit https://www.oncotarget.com

APRICOT! He’s here! On this special Friday episode, we share the journey of welcoming Forest into the world. Unexpectedly, during Jeri’s last appointment she was sent straight to the hospital for an immediate induction. It’s all fun and games until you hear “you would have had this baby in the car.”

In this episode Frances outlines the essential measurements to ensure your kitchen is functional and workable. She discusses the kitchen triangle and the theory behind how this works in your kitchen, cabinetry size standards, appliances, splashbacks and also some of the regulations to check.   SHOWNOTES Kitchen Triangle You need to be able to access things easily and move between key areas for food preparation such as your sink, fridge,stove top and ovens. Ideally, it you need to have a maximum of 7 metres between all these areas.   The theory behind it is-; Have bench space near the fridge so you can put your items down Adequate space next to the stovetop Easily unpack dishes from the dishwasher Space on either side of the sink (i.e for handwashing, preparation, washing vegetables and etc)   Check your local regulations with regards to how close a water source can be next to electricity– normally at least 500mm.   Splashbacks Check with the local building regulations but as a guide. Electric - 600mm between the stove and overhead cupboards Gas - 650mm from top rivet of the stove to underside of the lowest point on overhead cupboards Induction – 650mm   The height of your splashback may impact the splashback tile that you choose.   Cabinetry When we are doing deep dives with our clients, we consider how many people are going to use the kitchen so we can design it specifically on how many people are going to cook or prepare food in that space.   Between benches - 1000mm minimum is allowable but ideally it should be 1200mm. If there are two cooks working together, we would recommend a minimum of 1200mm between benches Between the Island bench and dining area, minimum measurement of It gives you adequate space for chairs to be pulled out and still be able to flow and walk between the spaces. Ideally, you need 300 millimeters between the edge of the bench and the sink. You don’t want to have your sink hard up against the edge of a bench as you have got nowhere to put anything down Ideally, the dishwasher should be 500mm from the corner – can also be placed at the end if need be. Ideally, 300-400mm bench space either side of stovetop Standard bench height is 900mm – go higher if you are taller Standard bench depth is 600mm Kicker/kickboard which is at the bottom of the cabinetry is generally anywhere between 90 and 150mm. Setback is about 50mm. Overhead cupboards are anywhere between 300-350mm deep Island bench Ideally it should be at a metre But in apartments that may not be achievable, so then they would be between 800mm-900mm. For benchtop overhangs, 400mm is a good measurement as it allows you to tuck stools under. However, 300mm is also sufficient. Benchtop – 8-40mm thick is available in various materials. Island bench can be a feature and be thicker than rear benches Suggest 20mm -25mm – depending on material – 40mm for feature stone Laminate benchtops 33mm as standard Solid acrylic surface can be any thickness Appliances From a functionality perspective, it’s better to have your microwaves either on the bench or overhead rather than underneath the bench. Standard dishwasher size is 600mm but you can get a smaller size at 450 mm. Not so popular in Australia as they are in Europe. Standard wall oven size 600mm – free standing ovens can be 600, 750, 800, 900 Fridge cavity – minimum 1000mm for a 900mm fridge & 1800mm high. If you want to future proof your space, measure your fridge cavity first so when you upgrade your fridge you will have enough space for the new one. Double sink allow about 800mm x 480mm deep   Available Services BEAUTIFUL KITCHEN DESIGN MADE EASY Ready to design and create your own beautiful kitchen? Get all the interior designer insider knowledge in this online course to create your dream kitchen. Join the waitlist so you’re the first to get the launch special offer!   BOOK A CHAT Ready to renovate or build your kitchen but not sure where to start? Get the help of a property expert and save yourself from making costly mistakes with a free Forever Home chat. Click here to get access to Frances' calendar;    KITCHEN BLISS PACKAGE Overwhelmed by the amount of decisions that need to be made when creating a stylish, functional and durable kitchen? What materials to select, what colours will co-ordinate together, what design is going to best suit the space, and your requirements. We offer kitchen design packages that include joinery design and material selections for a complete kitchen design. Click the link here to find more.     Related Resources: Episode 45: Kitchen Design Essentials - Internal Elevations & Joinery Design and you may watch our video for more info here. Read our latest blog on Internal Elevations and Joinery Design here. Episode 43: Kitchen Design Essentials – Flatpack Vs Custom Designed Kitchens Episode 41: Kitchen Design Essentials – Cabinetry Materials Episode 39: Kitchen Design Essentials – Splashbacks Episode 38: Kitchen Design Essentials-Benchtop Criteria and Materials – Part 2 Episode 36: Kitchen Design Essentials – Benchtops part 1  Episode 14: Forever Home LIVE- Joinery Drawings and Why Do Them Early On Episode 30: Kitchen Design Essentials -Kitchen Design Layouts and Location Episode 32: Kitchen Design Essentials – The Builder’s Insight  How to Choose the Right Bench Top Top 5 tips for selecting benchtops

Lecture SummaryThis podcasts reviews all of prenatal care and recommendations for how pregnant woman can stay safe during pregnancy. Much of this episode is based on my own personal practice. So much of pregnancy care is based on the current standard of care, expert opinion, and "what we have always done". More clinical trials are needed to find out what parts of prenatal care are important and what parts may be causing harm.Topics/Key Points- Pre-pregnancy- Getting pregnant- Finding out babies due date- 1st prenatal visit- Ongoing screenings throughout pregnancy- Pregnancy medical visits- Genetic testing- Vaccines during pregnancy- Later screenings- RhD negative moms- When to go to the hospital to have a baby- Diet during pregnancy- Foods to avoid in pregnancy- Exercise- Sexual intercourse- Activities to AvoidReferences- Pope et al. Sugar substitutes during pregnancy. Can Fam Physician. 2014.- Heuser C. Seafood, Spas, & Sandwiches presentation. University of Utah, Maternal Fetal Medicine. Available online.- Weihe and Grandjean. Cohort studies of Faroese children concerning potential health effects after the mothers' exposure to marine contaminants during pregnancy. Acta Vet Scand. 2012.- Golding et al. ALSPAC--the Avon longitudinal study of parents and children. I. Study methodology. Paediatr Perinat Epidemiol. 2001.- CDC. About teen pregnancy. Available online: https://www.cdc.gov/teenpregnancy/about/index.htm - CDC. Pregnancy rates for US women continue to drop. Available online: cdc.gov/nchs/products/databriefs/db136.htm.- Association for Safe International Road Travel. Road safety facts. Available online: https://www.asirt.org/safe-travel/road-safety-facts/#:~:text=Annual%20United%20States%20Road%20Crash,enough%20to%20require%20medical%20attention.- wikipedia.org, postpartum depression- wikipedia.org, mercury in fish- Keulen et al. Induction of labour at 41 weeks versus expectant management until 42 weeks (INDEX): multicentre, randomized non-inferiority trial. BMJ. 2019.- uptodate.com, nutrition in pregnancy- Jackson et al. Listeriosis outbreaks associated with soft cheeses, United States, 1998-2014. Emerg Inf Dis. 2018.- Drevets et al. Listeria monocytogenies: epidemiology, human disease, and mechanics of brain invasion. FEMs Immunology and Medical Microbiology. 2008.- JanakiramanV. Listeriosis in pregnancy: diagnosis, treatment, and prevention. Rev Obstet Gynecol. 2008.

In this episode, I interview parents Kristin and Zach Crosby, who live in Alabama with their four children. Kristin is a Registered Nurse, and has been a stay at home mom since the birth of their third child. They recently adopted a two year old. Zach is a systems administrator, and runs a locksmith company. They took the Evidence Based Birth® Childbirth Class with EBB Instructor Traci Weafer. We talk about Kristen’s first two hospital births, and what led her to take a different approach with her third - where she opted for a home birth. We also discuss their journey of self-advocacy in birth, and the importance of making informed decisions. "Babies Are Not Pizzas: They're Born, Not Delivered!" is available on Amazon, Barnes and Nobles, Kobo, Apple books, and more!  For more information and news about Evidence Based Birth , visit www.ebbirth.com. Find us on Facebook (https://www.facebook.com/EvidenceBasedBirth/), Instagram (https://www.instagram.com/ebbirth/), and Pinterest (https://www.pinterest.com/ebbirth/). Ready to get involved? Check out our Professional membership (including scholarship options) (https://evidencebasedbirth.com/become-pro-member/). Find an EBB Instructor here (https://evidencebasedbirth.com/find-an-instructor-parents/), and click here (https://evidencebasedbirth.com/childbirth-class/) to learn more about the Evidence Based Birth® Childbirth Class.

A new MP3 sermon from Partick Free Church of Scotland (Cont) is now available on SermonAudio with the following details: Title: Elders' Ordination & Induction Speaker: Andrew R Allan Broadcaster: Partick Free Church of Scotland (Cont) Event: Special Meeting Date: 8/23/2020 Bible: Acts 20:28 Length: 14 min.

The Ordination - Induction of Mr Murray Mackay, and the Induction of Mr David L Beveridge into the eldership of Partick Free Church of Scotland -Continuing- congregation on Sabbath morning 23 August 2020.

Join Amber, Coral, and Alec for a quick refresher about rituals and their importance so your chapter can lead meaningful fraternity ceremonies, even if you can't be together in person this year.

Induction or deduction? Scientism or spiritualism? The scientific method or the rhythm method? Grab a test tube and a wet nap, it's study time! I talk about knowing when it is or isn't your fault in your career, Russia's COVID-19 vaccine and philosophy in science. JR* the Podcast RSS

As you can see from the title of this episode, number 90 is a packed one! Carmen talks us through her 3 pregnancy and birth stories with her 4 babies! Carmen and her Husband worked through a fertility struggle with PCOS, eventually using Clomophine and falling pregnant after 3 rounds - Rosie was Breech right up to her birth and ended up being a C-Section birth so Carmen talks us through that along with everything else involved in becoming a Mum. Carmen then talks through falling pregnancy with Twins, her decision to try for a VBAC and her successful VBAC birth, learning life with twins and much more.Carmen then talks through falling pregnant with Taj, her experience juggling family, work and pregnancy and then her vaginal birth. This is a lovely episode and Carmen is such a gem, I know you're going to enjoy listening to her. She is also a Midwife and it's awesome hearing things from her professional perspective at times too. Thanks for joining me Carmen!This episode is sponsored by the Motherness Podcast, a beautiful, empowering podcast created by Kiwi Mum Skye Ross. I would love for you to show her support over at @Motherness.podcast on Instagram or find the podcast on Apple Podcasts, Spotify or wherever you like to listen.

In this episode we meet Michal, a midwife and mother to 3 boys who lives with her husband in Melbourne.Michal has had three very different birth experiences. Her most recent birth was only three months ago during the current COVID-19 pandemic where she was treated as a potential COVID-19 patient in labour due to her being ill at the time.Michal experienced a miscarriage before falling pregnant with her first son. His birth was an emergency caesarean despite reaching full dilation - which although she desperately wanted to avoid she knew it was the right decision immediately after he was born.When she fell pregnant again there was no hesitation as to whether or not to VBAC - she was having one. Two years after her first was born she gave birth vaginally to her second son. Although a very fulfilling VBAC there was something she wanted to do differently for her third labour, and this she did.Little did she know she would be giving birth to her youngest son in such an unprecedented time. She speaks about how this pregnancy was riddled with anxiety, particularly towards the end when isolation and lockdown measures set in and she began to feel unwell on top of this.Michal also generously shares suggestions to women who are giving birth at this time, particularly those in Victoria who are currently in lockdown.She recently created an Instagram account specifically to share her experience of pregnancy and postpartum in the hope that other mothers will connect and feel less isolated on their own journey. Search for: @midmumma~ Notes ~Post Natal Depression/Anxiety support: If you or anyone you know is affected by PND symptoms particularly at this time of COVID-19 please don't hesitate to contact the following support networks.The Gidget Foundationhttps://gidgetfoundation.org.au/get-support/,PANDAhttps://www.panda.org.au/info-support/pandas-national-perinatal-anxiety-depression-helplineBeyond Bluehttps://www.beyondblue.org.au/get-support/get-immediate-supportCopehttps://www.cope.org.auPregnancy Loss:https://www.bearsofhope.org.auhttps://rednosegriefandloss.org.auhttps://miscarriagesupport.org.au**VBAC Birth Stories features women's lived experiences. It is not intended to replace medical advice. Should you have any concerns during your pregnancy please always consult your healthcare provider.Please connect with us on Facebook or Instagram: @vbacbirthstories

Resources This series is brought to you by the Fascia Fanatic, Cherica Voyles, LMT offering massage and bodywork in Northeast Georgia. She can be found on Instagram at www.chericavoyleslmt.com (http://www.chericavoyleslmt.com/?fbclid=IwAR2zMgdXD-_uaLWxXHDf0_vHohbKkfrmzIBl9_Oa9qJc2mnDZOEf_uNRY_k) Did you subscribe to the podcast? Did you share this episode with all your friends? Private Online 200-hr Yoga and Ayurveda Teacher Training (https://spartanmindstrength.com/2020/05/15/online-200-hr-yoga-and-ayurveda-teacher-training-yoga-alliance/) Private Online 300-hr Ayurveda and Yoga Teacher Training (https://spartanmindstrength.com/online-300-hr-ayurveda-and-yoga-teacher-training-yoga-alliance/) Both trainings include three months of private mentorship after you complete the training in order to help you successfully implement everything you have learned in your professional and / or personal yogic / ayurvedic life Email us your feedback at: training@asktimandvie.com (mailto:training@asktimandvie.com) Instagram account: yogaenergyschool (https://www.instagram.com/yogaenergyschool/) Instagram account: ayurvedaoutlaws (https://www.instagram.com/ayurvedaoutlaws/) Our YouTube Channel: https://youtube.com/c/asktimandvie (https://youtube.com/c/asktimandvie) Yoga Energy's Training Library can be found at: https://squareup.com/store/training-courses (https://squareup.com/store/training-courses) Our favorite company for meat is US Wellness Meats (https://grasslandbeef.com/?affId=213910) You can help support our Podcast by giving as little as $1 per episode, our PayPal account is here: https://www.paypal.com/cgi-bin/webscr?cmd=_s-xclick&hosted_button_id=7FDYKCGSKL3NL&source=url (https://www.paypal.com/cgi-bin/webscr?cmd=_s-xclick&hosted_button_id=7FDYKCGSKL3NL&source=url) May we all be well, adapt and thrive! - Tim and Vie Gear Resources The 10X book Tim references: https://amzn.to/39WCOMM (https://amzn.to/39WCOMM) This is the XP-10 that we got: https://amzn.to/39XZiwO (https://amzn.to/39XZiwO) But since we got it long ago, we have the older version. The portable Induction cooktop that we use that does not drain the Kodiak Inergy: https://amzn.to/2PvZERK (https://amzn.to/2PvZERK) The Coleman bottletop that we use a lot: https://amzn.to/33uv2II (https://amzn.to/33uv2II ) The Ryobi flashlight that we use that takes the same rechargeable batteries the Ryobi tools use: https://amzn.to/31lxcrn (https://amzn.to/31lxcrn) The solar inflatable light we carry on the dashboard of the truck all the time: https://amzn.to/30vraFk (https://amzn.to/30vraFk) The JetBoil system that we use (older model) for heating up liquids in windy conditions: https://amzn.to/30wxhJN (https://amzn.to/30wxhJN) The propane camping stove that we use when we need something bigger than the Coleman single burner: https://amzn.to/30t1fOK (https://amzn.to/30t1fOK) This is similar to the inverter we use in the truck when we need to use the truck's battery as a charging source: https://amzn.to/2BZCLDc (https://amzn.to/2BZCLDc) Portable outdoor solar shower, very similar to the one we have: https://amzn.to/31oSRiA (https://amzn.to/31oSRiA) Our Inergy Kodiak Generator In Action Inergy Kodiak Solar Generator - Part 1 of 4: https://youtu.be/Kvl1D-_SKRA (https://youtu.be/Kvl1D-_SKRA) Inergy Kodiak Solar Generator - Part 2 of 4: https://youtu.be/r44lOBaNDYg (https://youtu.be/r44lOBaNDYg) Inergy Kodiak Solar Generator - Part 3 of 4: https://youtu.be/anhNpNcrQv8 (https://youtu.be/anhNpNcrQv8) Inergy Kodiak Solar Generator - Part 4 of 4: https://youtu.be/kUicDBG24S8 (https://youtu.be/kUicDBG24S8) Episode Transcript Tim: And today is about the Ayurvedic Prepper - Part 3. Tim: So today is part 3 of the ayurvedic prepper. And I want to go into a little bit about, again, breaking down the psychoticness of some of the preppers into what do you really need? And so I want to talk about electricity. Tim: So electricity, and this isn’t - this... Support this podcast

In this episode we are sharing the stories of our 2nd babies' births. Both began as inductions...One took an unexpected turn...Both left us feeling empowered...and when we look back on them, we can see how information and good support contributed to us both feeling really happy with our experiences. Join us as we talk about our 2nd births and maybe gain a different perspective on inductions.For more information about Exie's birth services click here

In this episode, I interview Miranda Kelly, a certified birth doula, postpartum doula, and childbirth educator who has worked for ten years in Indigenous people’s health planning, policy education, and research. Miranda holds a Bachelor of Science in Biology and Psychology, and a Master of Public Health degree. She is a mother of two girls, and is a member of the ekw’í7tl (pronounced ah-quay-tull) doula collective in Vancouver. Miranda is passionate about indigenous peoples reclaiming their authority as decision makers in their own health and wellbeing, and I’m thrilled to welcome Miranda to the podcast to let us know about the work that she and other community organizers are doing for the Indigenous community. We also discuss the evidence on amniotic fluid. For more information and news about Evidence Based Birth®, visit www.ebbirth.com. Find us on Facebook, Instagram, and Pinterest. Ready to get involved? Check out our Professional membership (including scholarship options) and our Instructor program. Find an EBB Instructor here, and click here to learn more about the Evidence Based Birth® Childbirth Class. RESOURCES: Follow Miranda at her website and Instagram. Click here for information on the ekw’í7tl doula collective. Click here to learn about the Doulas for Aboriginal Families Grant Program, administered by the BC Association of Aboriginal Friendship Centres. Click here to see the Society for Maternal Fetal Medicine guidelines on evaluation and management of polyhydramnios. For the Evidence Based Birth article What is the Evidence for Induction for Low Fluid at Term in a Healthy Pregnancy?, click here

For Us-Journey of a Trailblazer Follow Perky @PerkyPerspectives and @Perkysexycool Subscribe to the Perky Perspectives Podcast available on all streaming platforms and Like, Rate, Comment, and Share! Available on: Spotify, Youtube, Apple Podcast, Google Play, Patreon, ICN.DJ/Perky-Perspectives, Radio Public, Periscope, Stationhead, Perksofwellness.org, and ForUsNation.Com Patreon.Com/PerkyPerspectives Become a Patron!! For as little as $1 a month to support the podcast. Perky is also Looking for assistance with managing the Perks of Wellness Newsletter and Blog. Email at Perkyperspectivespod@gmail.com Hosted By Perky @PerkySexyCool Affiliated with: For Us Nation @ForUs4Us ForUsNation.Com Perksofwellness.Org TinyUrl.com/loveperiodproject Black Podcast Awards If you identify within the Black Diaspora and you podcast then check out Black Podcast Awards! Applications are open and we are also looking for sponsors and judges. Get more information at BlackPodAwards.Com and also follow on social media at BlackPodAwards Guest: Artisha “Tee” Bolding facebook.com/Artisha.bolding Instagram @artishabolding Twitter: @MissTyson https://tboldmedia.com thehealedgirl@gmail.com Anchor.fm/boldjourneyzz Join the TrailBlazers Community and get a free E-Book gift! Journal For your Journey Induction To Power Artisha Bio: Georgia-based Empowerment Coach and Author Artisha "Tee" Bolding is the Head of T Bold Media Group. She is best known for her loud belly laughs and love of Truth. As a consultant and speaker, Artisha has spent the last decade providing relationship and spiritual advice to friends, clients and youth groups. Artisha was inspired to write her first book the Journal, after a near fatal visit to the ICU due to medical mishap. Prayer and instructions from her Spiritual Father Bishop Hezekiah Pressley, Jr. Are the reason she walks in healing today! When she's not out shopping and missing DC ever so terribly, you can find her on a Twitter rant (@MissTyson) She knows God will do great things because we expect Him to! Induction To Power is specifically for those looking to level up personally and professionally. The mindset shift that this book will cause is going to change you forever. The INDUCTION book is going to ignite your mind and take you to the next level of flowing in your Purpose! Topics -How Artisha ended up in the ICU (medical Mishap) -Becoming an Author -Encouragement to get journey organized -Tools on your Journey -Purchase the Induction to Power book and Journal Book -Importance of Mentors -Think it, Say it, Write it -Join the Trailblazer newsletter Find out more at https://perky-perspectives.pinecast.co This podcast is powered by Pinecast. Try Pinecast for free, forever, no credit card required. If you decide to upgrade, use coupon code r-1aea92 for 40% off for 4 months, and support Perky Perspectives.

In this edition of "Shot Glass Diaries," Ian tells the story of the weekend he went to Cooperstown, New York in 2018 to witness the Major League Baseball Hall of Fame Induction Ceremony, which saw his favorite player of all time, Chipper Jones, along with five others inducted into the town's famous museum. From booking the trip the last minute to meeting baseball Hall of Famers and legends, to being interviewed on Fox Sports, hear all about Ian's trip where he was one of 55,000 to attend a ceremony in a town whose population is about 1,700 people!

Show #837   Good morning, good afternoon and good evening wherever you are in the world, welcome to EV News Daily for Sunday 12th June 2020. It’s Martyn Lee here and I go through every EV story so you don't have to.   Thank you to MYEV.com for helping make this show, they’ve built the first marketplace specifically for Electric Vehicles. It’s a totally free marketplace that simplifies the buying and selling process, and help you learn about EVs along the way too.   Welcome to a new Patreon PRODUCER LUC JOLLY   TESLA MODEL S AND MODEL X SPECIFICATIONS REVEAL 250 KW BOOST RATE "Tesla has updated the specifications of the S and X models to include a maximum boost rate of 250 kW or a charge rate of 1,000 miles per hour. Updates to the S and X models website align the load capacities of its flagship vehicles with those of the 3 and Y models." reports FR24news: Tesla recently increased the S and X models’ boost rate from 200 kW to 225 kW as part of software update 2020.24.6, before that, Model 3 and Model Y were the only vehicles in the company’s lineup that could take advantage of the 250 kW higher power of the V3 Superchargers. Tesla cites the improved preconditioning of the battery as a reason for the higher charge rate."   That was for the most recently built version of the Model S and X. But now it's up again from 225kW to 250kW. It's unclear what cars will take 250kW, whether it's the existing fleet or only cars sold from today.   Tesla: “Your car is now able to charge V3 Superchargers at peak rates of up to 225 kW. As usual, when you access a Supercharger, your car conditions its battery during the journey, so that it can charge more quickly. ”   And from Elon on Twitter, Tesla had to “increase some wire thicknesses in S/X to reduce resistive heating” in order to achieve the 250 kW charge speeds. So not the cells but the hardware in the car.   Many people point out the form factor difference in cells between S&X and 3&Y by forget that Tesla has improved the chemistry being used in the S&X cells to ensure they don't degrade as much when charging so quickly. Good news too for them being seen as the premium cars. It's also about safety and guaranteeing their products.   But how long will it hit 250kW for? And also it depends on how long it holds onto 250kW for...even if you ever hit that you have to be at a low state of charge and probably have navigated to the charger so it pre-conditions the temperature of the battery.   From a Car & Driver article in April: "We took our long-term 2019 Tesla Model 3 to a 250-kW Supercharger and a 150-kW Supercharger to test the difference. The 250-kW unit only saved approximately two minutes on comparable charges from 3 to 100 percent battery. the 250-kW charger only beats the lesser one in the range between about 10 percent and 50 percent state of charge, where all of the two-minute gain we saw over the entire charge was realized. Above that, the two closely follow the same path as the power necessarily tapers off as the battery level increases.  The overall charge time at the 250-kW Supercharger was one hour and six minutes, saving us two minutes over the 150-kW charger, which filled our battery from three to 100 percent in one hour and eight minutes."   https://www.caranddriver.com/news/a32132062/tesla-250-kw-vs-150-kw-supercharger-tested/   TESLA INCREASES MODEL Y PERFORMANCE RANGE TO 291 MILES "Tesla has increased the range of the Model Y Performance from an EPA-rated 280 miles to 291 miles when equipped with the factory 21-inch Überturbine wheels.  The range boost represents an approximate 3.9% increase despite the vehicle having no noticeable hardware differences, according to the description outlined on Tesla’s Model Y online configurator. Model Y Long Range retains its 316-mile rating." says Teslarati: "Model Y Performance is currently offered with only the heavyset 21″ Überturbine wheels, which tips the scale at a whopping 65 lbs (29 kg) each. The heavy rotational mass is the main culprit for the decrease in range over the  20″ Induction wheels that Tesla briefly offered for Performance buyers." On the Model Y Long Range you can choose the 19" Gemini Wheels which are included, or the 20" Induction wheels for $2,000.   So it now has an extra 11 miles of official range, for $3,000 less.   https://www.teslarati.com/tesla-model-y-range-21-in-uberturbine-wheels/   DELTA LAUNCHES 200KW ULTRA FAST ELECTRIC VEHICLE (EV) CHARGER Delta, a global leader in power and thermal management solutions, today announced the launch of its next-generation 200kW Ultra Fast Charger (UFC200) in the Europe, Middle East & Africa (EMEA) region. Delta's UFC200, which is capable of enabling a 100km driving range with roughly 8 minutes of charging, aims to serve next-generation EVs, e-trucks and e-buses in a broad range of applications such as highways, parking lots, service stations, logistics companies as well as urban traffic hubs. The UFC200 is also meeting the EV owner's demands for quick and easy charging, realised by its 200kW capacity, which can be split in 2 x 100kW to enable two EVs to be charged simultaneously via the innovative non-liquid cooled 400A high power CCS cable/connector system. This temperature controlled high power connector system can supply extra power when the EV's battery system is at low charge without oversizing the system. In extreme environments and very frequent usage, the power will be automatically reduced to keep the cable/connector temperature in a safe range for the user.   https://finance.yahoo.com/news/delta-launches-200kw-ultra-fast-083000525.html   E-SCOOTER TRIALS COULD SEE THE UK MOVE BEYOND EU RULES "As the UK fast-tracks the e-scooter trials, the new regulation just being tested could lead to a more generous classification of light electric vehicles than applied across the EU. It could see not only e-scooters but also light electric mopeds without type-approval being allowed." says electrive in a special report today: "Where European capitals have long since introduced the light electric vehicles and already been through the inevitable trials necessary to initiate usage that was acceptable for other street users and residents, the Isles had banned the electric kick scooters from its roads. The government speeding up the e-kick-scooter trial process by a year and widening it to the entire country. However, for the time being, the e-scooters should continue to be categorized as motor vehicles, the trial period will be used to investigate whether they should have the same legal status as EPACs permanently. So, for now, users must have a motor vehicle insurance and at least an AM driving license"   https://www.electrive.com/2020/07/12/e-scooter-trials-could-see-the-uk-move-beyond-eu-rules/   25 HIGH CAPACITY HYDROGEN STATIONS TO CONNECT THE NETHERLANDS, BELGIUM, AND WEST GERMANY Air Liquide and the Port of Rotterdam Authority announce the launch of a jointly created initiative, which aims at enabling 1,000 hydrogen-powered zero-emission trucks on the roads connecting the Netherlands, Belgium, and West Germany by 2025. In order to have 1,000 Hydrogen-powered trucks on the road, out of which 500 are expected to be based in the Port of Rotterdam area, the related infrastructure needs to be developed and deployed, which envisages 25 high capacity hydrogen stations to connect the Netherlands, Belgium, and West Germany. The project also aims to include the necessary electrolysis capacity to produce low carbon hydrogen. The companies represented in the initiative will jointly perform the feasibility study of this whole value chain.   https://www.portofrotterdam.com/en/news-and-press-releases/air-liquide-and-port-of-rotterdam-authority-hydrogen-road-transport   COBALT-FREE LFP BATTERIES ARE GAINING TRACTION "Until recently LFP battery packs were mostly used in electric buses, since this kind of vehicles don’t require very energy dense batteries to be eligible for government subsidies in China. However, recent energy density increases in LFP battery packs made possible that passenger electric cars can also use this kind of cobalt-free batteries and still be eligible for government subsidies." says PushEVs: "Now that extremely popular newcomers such as the Tesla Model 3 SR+ MIC (Made in China) and the BYD Han EV arrived with LFP batteries, a production boost in this battery chemistry was inevitable. Anyway, this is just starting. I think that next year the rise of LFP batteries usage could be exponential, for at least three reasons: BYD invades Europe,  Tesla Model C, CATL battery cell plant in Germany Summing up, good cobalt-free batteries are already available and they make possible for electric cars to compete in price and availability with ICE cars"   Read more from Pedro here: https://pushevs.com/2020/07/11/cobalt-free-lfp-batteries-are-gaining-traction/   [mention for Premium Partners]   You can listen to all 836 previous episodes of this this for free, where you get your podcasts from, plus the blog https://www.evnewsdaily.com/ – remember to subscribe, which means you don’t have to think about downloading the show each day, plus you get it first and free and automatically.   It would mean a lot if you could take 2mins to leave a quick review on whichever platform you download the podcast.   And if you have an Amazon Echo, download our Alexa Skill, search for EV News Daily and add it as a flash briefing.   Come and say hi on Facebook, LinkedIn or Twitter just search EV News Daily, have a wonderful day, I’ll catch you tomorrow and remember…there’s no such thing as a self-charging hybrid.     PHIL ROBERTS / ELECTRIC FUTURE (PREMIUM PARTNER) BRAD CROSBY (PREMIUM PARTNER) AVID TECHNOLOGY (PREMIUM PARTNER) BRIGHTSMITHGROUP.COM – FOR CLEANTECH TALENT (PREMIUM PARTNER) PORSCHE OF THE VILLAGE CINCINNATI (PREMIUM PARTNER) AUDI CINCINNATI EAST (PREMIUM PARTNER) VOLVO CARS CINCINNATI EAST (PREMIUM PARTNER) NEW! 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On today's episode, Dr Joseph Sgroi (OBGYN) talks with Vanessa about her birth story. Vanessa's birth story features discussions around NIPT testing, nuchal translucency, amniocentesis, induction, syntocinon, vaginal birth, postnatal anxiety, braxton hicks, External cephalic version (ECV), prostaglandin.Dr Joseph Sgroi is a highly experienced obstetrician, gynaecologist and fertility specialist in Melbourne. You can find Dr Joseph Sgroi on Instagram @drjosephsgroi or his website at www.drjoseph.com.au.This episode is proudly brought to you by Tiny Hearts Education; our mission is to bring education to all Australian parents through first aid and birthing courses so they can move through pregnancy, childbirth and parenthood with confidence. Visit www.tinyheartseducation.com for more information.

In this episode we are discussing both natural and pharmaceutical induction methods. Everyone knows someone, or is that someone, who has been induced or tried to naturally induce themselves. Maybe you are pregnant and wondering if induction is the right choice for you and your baby. We explore some of those options and the reasons why inductions may be chosen, as well as some caution when induction is being considered.Referenced in this episode: https://evidencebasedbirth.com/?s=natural+induction https://www.nationalpartnership.org/our-work/resources/health-care/maternity/listening-to-mothers-iii-pregnancy-and-birth-2013.pdfhttps://www.acog.org/en/Clinical/Clinical%20Guidance/Committee%20Opinion/Articles/2013/11/Definition%20of%20Term%20PregnancyTo learn more about Exie's Private Childbirth Classes and Birth Doula Support: https://www.tranquiltouchforwomen.com/birth-services/

Tamer Selima takes a deeper dive into the advantages and complexities in common applications using flame, Induction, and resistance heating methods. He helps us understand how the processes work and where each method can be used.