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Behind The Knife: The Surgery Podcast
Building the House of Surgical Education: The Legacy of Dr. Ajit Sachdeva

Behind The Knife: The Surgery Podcast

Play Episode Listen Later Aug 31, 2026 38:47


What does it take to build a national surgical education apparatus from scratch? In this episode, we sit down with Dr. Ajit Sachdeva, the former Senior Vice President for Education at the American College of Surgeons—a role he held for 24 years before passing the torch in fall 2025. When Dr. Sachdeva arrived at the ACS in 2001, there was no division, no script, and almost no structure. Over the course of his tenure, he created an ecosystem that now touches surgeons at every stage of their careers, from the first year of medical school to the last year of practice.Dr. Sachdeva reflects on competence, excellence, and the value of surgical educators. He discusses the structural shifts that have shaped modern surgical training, including simulation standards, competency-based curricula, the ACS Accredited Education Institutes, and the Academy of Master Surgeon Educators. He also shares his thoughts on the challenges that remain: resource constraints, the tension between clinical productivity and educational investment, and the gap between national standard-setting and local implementation.Join hosts Pooja Varman, MD, Judith French, PhD, and Jeremy Lipman, MD, MHPE to reflect on Dr. Sachdeva's impact on surgical education.Learning ObjectivesBy the end of this episode, listeners will be able to 1.     Distinguish between competence, proficiency, expertise, and mastery in the context of surgical training and career development.2.     Identify key structural initiatives from the ACS Division of Education and describe their impact on surgical education at the national level.3.     Discuss the challenges of sustaining and funding surgical education infrastructure and articulate strategies for aligning educational goals with institutional priorities.  References1.     ACS Accredited Education Institutes: https://www.facs.org/for-medical-professionals/education/programs/accredited-education-institutes/ 2.     Dr. Ajit Sachdeva Describes a Career of Distinction in Practice and Surgical Education | ACS. Accessed March 27, 2026. https://www.facs.org/for-medical-professionals/news-publications/news-and-articles/acs-brief/october-21-2025-issue/dr-ajit-sachdeva-describes-a-career-of-distinction-in-practice-and-surgical-education/ Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more.  If you liked this episode, check out our recent episodes here: https://behindtheknife.org/listenBehind the Knife Premium: https://behindtheknife.org/premiumOral Board Review: https://behindtheknife.org/oral-boardOral Board Simulator: https://behindtheknife.org/oral-board/simulatorGeneral Surgery Oral Board Review Course: https://behindtheknife.org/premium/general-surgery-oral-board-reviewTrauma Surgery Video Atlas: https://behindtheknife.org/premium/trauma-surgery-video-atlasDominate Surgery: A High-Yield Guide to Your Surgery Clerkship: https://behindtheknife.org/premium/dominate-surgery-a-high-yield-guide-to-your-surgery-clerkshipDominate Surgery for APPs: A High-Yield Guide to Your Surgery Rotation: https://behindtheknife.org/premium/dominate-surgery-for-apps-a-high-yield-guide-to-your-surgery-rotationVascular Surgery Oral Board Review Course: https://behindtheknife.org/premium/vascular-surgery-oral-board-reviewColorectal Surgery Oral Board Review Course: https://behindtheknife.org/premium/colorectal-surgery-oral-board-reviewSurgical Oncology Oral Board Review Course: https://behindtheknife.org/premium/surgical-oncology-oral-board-reviewCardiothoracic Oral Board Review Course: https://behindtheknife.org/premium/cardiothoracic-surgery-oral-board-reviewOBGYN Oral Board Review Coures: https://behindtheknife.org/course/obgyn-oral-board-reviewEPA Playbook: https://behindtheknife.org/course/epa-playbookSurgical Instrument Flashcards: https://behindtheknife.org/course/surgical-instrument-flashcardsABSITE Review: https://behindtheknife.org/course/absite-2026-exam-reviewDownload our App:Apple App Store: https://apps.apple.com/us/app/behind-the-knife/id1672420049Android/Google Play: https://play.google.com/store/apps/details?id=com.btk.app&hl=en_US

Frankly Speaking About Family Medicine
500th Episode: Hot Topics, Then and Now - Frankly Speaking Ep 500

Frankly Speaking About Family Medicine

Play Episode Listen Later Aug 31, 2026 41:25


Credits: 0.75 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-500 Overview: To celebrate our 500th episode, each member of our team revisits a popular topic from the podcast's earlier installments—GLP-1s, cervical and breast cancer screening, diet and exercise, contraception, hypertension, and lipid management—to trace how the evidence and guidelines have changed since it was first covered. Whether you're catching up or reinforcing what you know, this milestone episode helps you bring the latest evidence into everyday patient care. Guest: Robert Baldor, MD, Alan Ehrlich, MD, Susan Feeney, DNP, FNP-BC; FAANP, Jillian Joseph, PA, Mariyan L. Montaque, DNP, FNP-BC, Jill Terrien PhD, ANP-BC, FAAN   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com  Episode resource links:  Zhou H et al.  Evaluation and Comparison of the PREVENT and Pooled Cohort Equations for 10‐Year Atherosclerotic Cardiovascular Risk Prediction. Journal of the American Heart Association Volume 14, Number 4 Goff DC et al. 2013 ACC/AHA guideline on the assessment of cardiovascular risk: a report of the American College of Cardiology/American Heart Association task force on practice guidelines. Circulation. 2014;129:S49–S73. Circulation. 2018 Jul 24;138(4):345-355.  eClinicalMedicine 2025: 103741. Curry, J. (2018). Screening for cervical cancer: US Preventive Services Task Force Recommendation Statement. JAMA.320(7):674-686. doi:10.1001/jama.2018.10897 https://www.ncbi.nlm.nih.gov/pubmed/30140884  Perkins RB, Wolf AMD, Church TR, et al. Self-collected vaginal specimens for human papillomavirus testing and guidance on screening exit: An update to the American Cancer Society cervical cancer screening guideline. CA Cancer J Clin. 2026;e70041. doi:10.3322/caac.70041   Screening for Cervical Cancer (2026). Obstetrics & Gynecology, 148(1), e63-e67. https://doi.org/10.1097/AOG.0000000000006257  Jad Zeitouni, Nosayaba Osazuwa-Peters, Yusuf Dundar, Gregory Zimet, Mark A. Varvares. (2025). Two decades of the HPV vaccine: its promise, progress, prospects, projections, and posterity, The Lancet Regional Health - Americas, (51), https://doi.org/10.1016/j.lana.2025.101243 Diabetes, Obesity and Metabolism 28, no. 6 (2026): 5043–5057, https://doi.org/10.1111/dom.70698.  Relationship of early rapid weight loss to efficacy and safety of tirzepatide and semaglutide for obesity: SURMOUNT-5 post hoc analysis. Am J Med. 2026 Jul;139(7):913-921. doi: 10.1016/j.amjmed.2026.03.010 US Preventive Services Task Force; Nicholson WK, Silverstein M, Wong JB, et al. Screening for breast cancer: US Preventive Services Task Force recommendation statement. JAMA. 2024;331(22):1918–1930.  Trentham-Dietz A, Chapman CH, Jayasekera J, et al. Collaborative modeling to compare different breast cancer screening strategies: a decision analysis for the US Preventive Services Task Force. JAMA. 2024;331(22):1931–1946. Giaquinto AN, Sung H, Miller KD, et al. Breast cancer statistics, 2022. CA Cancer J Clin. 2022;72(6):524–541.  Qaseem A, Harrod CS, Balk EM, et al. Screening for breast cancer in asymptomatic, average-risk adult females: a guidance statement from the American College of Physicians (Version 2). Ann Intern Med. 2026.:  American Cancer Society. Breast Cancer Facts & Figures 2022–2024. Atlanta, GA: American Cancer Society, 2022.  Hu X, Chehal PK, Kaplan C, et al. Racial differences in patient-reported symptoms and adherence to adjuvant endocrine therapy among women with early-stage, hormone receptor-positive breast cancer. JAMA Netw Open. 2022;5(8):e2225485.  Torres JM, Sodipo MO, Hopkins MF, Chandler PD, Warner ET. Racial differences in breast cancer survival between Black and White women according to tumor subtype: a systematic review and meta-analysis. J Clin Oncol. 2024;42(35):4225–4234.  Bailey ZD, Krieger N, Agénor M, Graves J, Linos N, Bassett MT. Structural racism and health inequities in the USA: evidence and interventions. Lancet. 2017;389(10077):1453–1463. Hypertension. 2026;83:00–00. DOI: 10.1161/HYPERTENSIONAHA.125.25787 Allen RH, Bartz D. Opill: The Over-the-Counter Contraceptive Pill. Obstet Gynecol. 2024;143(2):184-188. doi:10.1097/AOG.0000000000005455  Cahill EP, Kaur S. Advances in contraception research and development. Curr Opin Obstet Gynecol. 2020;32(6):393-398. doi:10.1097/GCO.0000000000000666  Charles DN, Nagarsheth M, Oshman L. Pain Management for IUD Insertion in Primary Care. Am Fam Physician. 2025;111(4):299-301.  Chen, C., Strasser, J., Banawa, R., Luo, Q., Bodas, M., Castruccio-Prince, C., Das, K., & Pittman, P. (2022). Who is providing contraception care in the United States? An observational study of the contraception workforce. American journal of obstetrics and gynecology, 226(2), 232.e1–232.e11. https://doi.org/10.1016/j.ajog.2021.08.015  Diedrich,J., Klein, D. Peipert, J.(2017). Long-acting reversible contraception in adolescents: a systematic review and meta-analysis, Am J Ob Gyn, April 2017. http://dx.doi.org/10.1016/j.ajog.2016.12.024  Li RHW, Lo SST, Gemzell-Danielsson K, Fong CHY, Ho PC, Ng EHY. Oral emergency contraception with levonorgestrel plus piroxicam: a randomised double-blind placebo-controlled trial. Lancet. 2023;402(10405):851-858. doi:10.1016/S0140-6736(23)01240-0  Mørch LS, Meaidi A, Corn G, Hargreave M, Wessel Skovlund C. Breast Cancer in Users of Levonorgestrel-Releasing Intrauterine Systems. JAMA. 2024;332(18):1578–1580. doi:10.1001/jama.2024.18575  Nguyen AT, Curtis KM, Tepper NK, et al. U.S. Medical Eligibility Criteria for Contraceptive Use, 2024. MMWR Recomm Rep. 2024;73(4):1-126. Published 2024 Aug 8. doi:10.15585/mmwr.rr7304a1  Paradise SL, Landis CA, Klein DA. Evidence Based Contraception: Common Questions and Answers. American Family Physician. 2022. https://www.aafp.org/afp/2022/0900/contraception The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.

NeuroDiverse Christian Couples
What is the Connection of NeuroInflammation & Autism with Dr. Eric Weiss

NeuroDiverse Christian Couples

Play Episode Listen Later Aug 31, 2026 45:30 Transcription Available


Discussion: Dr. Holmes and Dr. Weiss discuss the John Hopkins and current Duke University studies on neuroinflammation and the brain, with specifics on the impact on the autistic brain. Dr. Weiss shares his personal story of stem-cell treatment and the impact on his young adult son with autism who went from having a few words at the age of 23 to living independently. Dr. Eric Weiss is a leader in advanced regenerative medicine and the co-author of Educating Marston. Founder of the North Florida Stem Cells Clinic, Dr. Weiss provides stem cell replacement therapy to treat various conditions such as Osteoarthritis (OA), Rheumatoid Arthritis (RA), and Traumatic Brain Injury (TBI), with a special focus on the treatment of Autism. Dr. Weiss co-wrote Educating Marston with his wife, Christine Weiss, as a memoir of their journey through programs and therapies to improve the quality of life of their autistic son, Marston. Trying seemingly everything under the sun, nothing clicked until they discovered stem cell replacement therapy in conjunction with intensive work at programs like the Institutes for the Achievement of Human Potential. Once with limited verbal communication abilities, Marston can now hold a conversation and do so much more. With Educating Marston, Dr. Weiss is on a mission to help fellow parents of children on the autism spectrum and spread the word about stem cell replacement therapy as a treatment therapy for autism. Dr. Weiss and Educating Marston have been featured on local and national outlets including LA Weekly, Life & Style, Wake Up with Marci, and more. A graduate of Duke University Medical School, Dr. Weiss completed his general surgery residency in the University of California system and a Plastic and Reconstructive Surgery residency at the University of Miami. Board certified in Plastic and Reconstructive Surgery (American Board of Plastic Surgery), Dr. Weiss is also a Fellow (FACS) in the American College of Surgeons, Diplomate of the National Board of Medical Examiners, Member of the American Society of Plastic Surgeons (ASPS) and the Greater Jacksonville Society of Plastic and Reconstructive Surgeons, and a volunteer with “Hands Healing Hearts,” which makes annual medical missions to South America to perform reconstructive surgery on patients with birth defects. Dr. Weiss lives with his wife Christine in sunny Jacksonville, Florida.  Buy the Book HereEducating Marston WebsiteNorth Florida Stem Cells WebsiteMedical Daily Article 

A Quest for Well-Being
Understanding BPH: A Guide for Couples

A Quest for Well-Being

Play Episode Listen Later Aug 30, 2026 53:11


— Today's conversation is about a health issue that affects millions of families but is rarely talked about openly. While it primarily impacts men, it often becomes a shared experience for couples. If your partner is waking up several times a night to use the bathroom, struggling with urinary symptoms, or simply saying, "It's just part of getting older," this episode is for you. Benign prostatic hyperplasia, or BPH, is an incredibly common condition as men age, yet many delay seeking help—even though effective treatments are available. The result isn't just interrupted sleep for them; it can affect the well-being, rest, intimacy, and quality of life of both partners. Today, we'll explore what BPH really is, the signs to look for, how to start compassionate conversations with a loved one, and the treatment options that can help men regain comfort, confidence, and a better quality of life. Joining us today is urologist Dr. Sravan Panuganti, who specializes in men's urologic health and is passionate about helping patients find effective, personalized solutions so they can get back to living life more fullyValeria sits with Dr. Sravan Panuganti — He is a urologist with Carolina Urology Partners and an assistant professor in urology at the Virginia College of Osteopathic Medicine in Spartanburg, S.C. Dr. Panuganti completed his college education at the University of Pittsburgh. He then went on to medical school at the Philadelphia College of Osteopathic Medicine and completed his residency in urological surgery at Jefferson New Jersey Hospitals in Southern New Jersey, followed by a fellowship in men's sexual medicine at MD Anderson Cancer Center and University of Texas Health Science Center in Houston, Texas. He is also a fellow of the American College of Osteopathic Surgeons. His specialty interests in urology include benign prostatic hyperplasia (BPH) and erectile dysfunction (ED). He believes in early intervention for BPH and is trained in a variety of treatment options. He lives in Charlotte with his wife, two kids, and dog. To learn more about Dr. Sravan Panuganti and his work, please visit: https://www.laborie.com/patients/conditions/optilume-for-bph/

ZOE Science & Nutrition
The 5 best food swaps to lower cholesterol, protect your heart and to live longer | Dr. Alice Lichtenstein

ZOE Science & Nutrition

Play Episode Listen Later Aug 27, 2026 52:26


Is fat good or bad for your heart? For decades, we blamed fat and cholesterol for clogged arteries and heart attacks. Now you choose low-fat yogurt to protect your heart, while others cook with beef tallow. In this episode, Dr. Alice Lichtenstein, a world-leading expert on dietary fat and heart health, helps settle the debate. Dr. Lichtenstein explains which fats protect your heart and which to cut back on, you'll learn what raises your cholesterol, and why the type of fat you eat matters more than how much of it you eat. You'll leave the episode with some practical food swaps to protect your heart and live longer. Have you swapped butter for "low-fat" alternatives loaded with sugar? Could that choice be working against your heart?

Your Healthiest Healthy with Samantha Harris
The Coffee & Sleep Lies You Believe: The Surprising Habits That Protect Your Brain for Life with guest expert Dr. David Perlmutter — #70

Your Healthiest Healthy with Samantha Harris

Play Episode Listen Later Aug 25, 2026 50:11


If you've ever wondered whether your daily habits are quietly protecting your brain, or quietly working against it, this one's for you. Some of the most powerful things you can do for your memory, your focus, and your long-term brain health aren't found in a prescription. They're in your morning coffee, your nightly sleep, and the way you help your body recover every single day.I'm joined by returning guest expert Dr. David Perlmutter, a board-certified neurologist and 6-time New York Times bestselling author, to unpack the real science on the choices that shape cognitive function, metabolism, and longevity. We get into why coffee is so much more than caffeine, how deep sleep literally washes waste out of your brain overnight, why tracking your sleep might be one of the smartest health moves you make, and what the research actually says about infrared saunas, cold plunges, and heart rate variability. It's practical, it's evidence-based, and you can start using it today.What You'll Learn:• Why coffee is far more than caffeine, and the 90-plus bioactive compounds that may help protect your brain• The daily coffee sweet spot, and the "caffeine curfew" that guards your deep sleep• How to choose cleaner coffee: organic, mold-free, water-processed decaf, and why flavored blends are a gamble• Quality over quantity: why "I slept 8 hours" tells you almost nothing about your brain• How deep sleep activates the glymphatic system to wash away waste tied to cognitive decline, and the minimum you should aim for• The everyday habits that quietly sabotage restorative sleep, and why a wearable can help you fix them• What HRV really measures, why higher means more resilient, and simple ways to raise yours• Hot & Cold therapy: What the science says about infrared saunas and cold plunges, and why heat and cold may share the same protective pathways• A crucial caution for breast cancer survivors and anyone at risk for lymphedema before starting heat or cold therapy• The Mouthwash Habit Your Didn't Realize Is Harming You: The surprising connection between your mouth bacteria, mouthwash, blood pressure, and blood sugar• Brain-Boosting Movement: Why exercise acts like medicine, turning your muscles into hormone-producing organs that support your brain...and so much more!About Our Guest Expert:Dr. David Perlmutter is a board-certified neurologist, Fellow of the American College of Nutrition, and 6-time New York Times bestselling author. Recognized as one of the world's leading voices in brain health, he has spent decades translating cutting-edge neuroscience into practical strategies that help people reduce their risk of neurodegenerative disease and support lifelong wellness. He's the author of bestsellers including Grain Brain, Brain Wash, and Drop Acid, with his newest book, Brain Defenders, released in 2026.Connect with Dr. David Perlmutter:Instagram: @davidperlmutterFacebook: Dr. David PerlmutterWebsite: drperlmutter.com_________________________________________Get Cleaner, Regulated, Better Supplements for LessDid your last order of vitamins come off a big online overnight shipping platform but you have no idea how long it was sitting in an overheated warehouse?Or maybe those Omega-3's you take are actually rancid but you wouldn't know?That's why I'm excited to have found a platform that is not only efficacious and 3rd-party lab tested, but also regulated to have the ingredients in them that are on the label!And Fullscript has 100+ brands of supplements you may already be taking…only better. Safer. What your family needs.Yup — your one-stop shop for high-quality wellness and supplement products from brands people actually trust.Better still? I have been able to secure the most awesome discounts for you. Every order. Every day of the year. Even more savings with auto-ship.Whether you're leveling up your health routine, trying to stay consistent, or just attempting to remember to take your vitamins before 11 PM, Fullscript makes the whole process way easier.✨ Easy online ordering✨ Practitioner-trusted supplement brands✨ Personalized wellness support✨ Delivered straight to your door (because leaving the house is optional)Just click HERE to set up a free account. Or visit:https://us.fullscript.com/welcome/samanthaharris_store/store-start_________________________________________Why wash clothes with toxic cleaners? Try this instead!It shocked me that our laundry rooms are often one of the most toxic places in our homes.After breast cancer, I began changing out my personal care and beauty but didn't even think about my cleaning supplies.For laundry, I found a few brands that are really clean and free of harmful ingredients, but still searched for that fresh scent without the toxic junk.Found it finally! Here is the link to it (and you can message me to check to see if there are any great offers happening with current savings!CLICK THIS LINK for the details and get 100 FREE LOADS

Frankly Speaking About Family Medicine
Recalculating Risk: Updated Guidelines for Lipid Management - Frankly Speaking Ep 499

Frankly Speaking About Family Medicine

Play Episode Listen Later Aug 24, 2026 15:02


Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-499 Overview: Stay in the know with this breakdown of the latest American College of Cardiology (ACC)/American Heart Association (AHA) recommendations for lipid testing and management. New approaches to evaluating hyperlipidemia, as well as limitations of the updated guidelines, are discussed to provide you with practical strategies for tailoring treatment decisions to individual patient risk. Episode resource links: Writing Committee Members, Blumenthal RS, Morris PB, et al. 2026 ACC/AHA/AACVPR/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Dyslipidemia: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation. 2026;153(17):e1154-e1276.  Guest: Alan M. Ehrlich, MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com  The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.

Ralph Nader Radio Hour
Quadcopters and Rolling Coups

Ralph Nader Radio Hour

Play Episode Listen Later Aug 22, 2026 123:44


Ralph welcomes Dr. Mimi Syed to discuss the recent report from Brown University's Costs of War Project: “Lethal Precision Without Accountability: Israeli Government ‘Quadcopter' Use in Gaza.” Then, Ralph speaks to Joel McCleary (former Deputy Assistant to President Jimmy Carter and international consultant) about his “Dancing in the Dark” essay series on the strategies that Trump is using to hold onto power at almost any cost.Dr. Mimi Syed is an emergency medicine physician and assistant clinical professor at University of Washington and Washington State University, and a fellow of the American College of Emergency Physicians. Dr. Syed served in Gaza at both al-Aqsa Hospital and Nasser Hospital, where she documented severe injuries from drone strikes and she has firsthand experience treating civilians targeted by the IDF. She is co-author of the Costs of War Project's new report: Lethal Precision Without Accountability: Israeli Government “Quadcopter” Use in Gaza.A lot of the attention has essentially fallen off from Gaza because of this so-called ceasefire…And the media (Western media) unfortunately is complicit in this—has no interest in covering Gaza, has no interest in covering the ongoing slaughter that's happening in Gaza.Dr. Mimi SyedThe irony of all of this is that the drones and the capabilities that these drones have to shoot and to distinguish between a civilian and a combatant—the whole purpose of this is to mitigate civilian harm. And instead, perversely, they're being used for the opposite. They're being used to target civilians and children. And in the U.N. report, they specifically talk about a soldier describing the experience, saying that it's like a video game. He can be sitting somewhere far away, away from the dangers of a military zone, away from the dangers of combatants, and essentially target whoever he wants, and shoot. And these drones have the capability of distinguishing between a child, an adult, a combatant. And most of these cases that I documented, the child was by themselves. There was no other adult harmed.Dr. Mimi SyedJoel McCleary served as Deputy Assistant to the President during the Carter Administration. As president of the Sawyer-Miller Group he oversaw international strategic advisory work for fourteen prime ministers and presidents. Currently, he is Managing Partner of Four Seasons Ventures, which has conducted in-depth studies for the Department of Defense and Department of Homeland Security on biodefense. These studies reviewed the emergency powers of the President in the event of a pandemic or major biological weapons attack. He is co-founder of the nonpartisan nonprofit Keep Our Republic.November 3rd is just the prelude to January 3rd—the game (so to speak) is who controls the Speakership. And that is determined by the certified members who are certified by the current House—they will determine who meets on January 3rd. So obviously what Trump does not want (or any President does not want) is there to be an opposing party's Speaker.Joel McClearyWe're not saying that anything is inevitable. We're just saying what is possible if you look at what they're saying and if you look at where they might go if they feel compelled to do so. So NSPM-7 is probably the most frightening aspect of this whole thing. And what's most frightening is how few people have focused on it. All of us need to read these documents at the ACLU (the Brennan Center has done fantastic work). And Mark Medish and I just are appalled that still, in Democratic circles or other circles, we are not yet comprehending the meaning of NSPM-7 and how it threatens each one of us in reality.Joel McClearyNews 8/21/26* This week, another round of primaries were held, most notably in Florida. For progressives, the biggest victory is that of Angie Nixon, a DSA-backed member of the Florida House of Representatives, representing Jacksonville. Nixon trounced her opponent – Alex Vindman, who testified against Trump during the 2019 impeachment effort – winning 56% of the vote to his 44% despite being outspent by a margin of 16 to 1. Forbes reports that in her victory speech, Nixon said “We have proved that everyday people are more powerful than corporations and billionaires…We went up against the political establishment, against millions of dollars of outside spending…and we won. This win was for the little guys and girls…We, the hardworking everyday people of Florida, sent a shock wave to the Washington, D.C., establishment.” Unfortunately, Nixon's candidacy, like that of any statewide Democratic campaign in the Sunshine State, remains a long shot. The last Democrat to win a U.S. Senate seat in Florida was former astronaut Bill Nelson in 2012.* More disappointing were the down-ballot results in these primaries. In the 20th congressional district, a majority-minority district centered on Broward County, Debbie Wasserman Schultz won with 45% of the vote, according to NBC. She defeated four Black candidates, including young progressive Elijah Manley. Wasserman Schultz previously represented the 25th district, but following the Republican-led mid-decade redistricting program carried out in Florida, she opted to seek reelection in this heavily Democratic seat. The Black candidates had tried and failed to consolidate behind a single choice.* And in Florida's 25th congressional district, ultra-zionist incumbent Congressman Jared Moskowitz “warded off” a challenge from his left in the form of Oliver Larkin, a DSA-backed union organizer. Larkin drew substantial media attention, first when he appeared on Fox and, asked about immigration and crime, he demanded accountability for “this pedophile president Donald Trump” and others implicated in the Jeffrey Epstein scandal and again during an interview with WPLG Local 10 when Larkin was “faced with genocide denial.” According to the Middle East Eye, Larkin “raised the topic of Israel's genocide in Gaza, pointing to statements and findings from institutions such as the United Nations, Amnesty International and Israeli human rights organisation B'Tselem,” which the interviewer, Glenna Milberg incorrectly dismissed as “factually incorrect.” Larkin “outlined Israel's deliberate targeting of civilians, restrictions on humanitarian aid and attacks on churches, schools and other places of worship,” and Milberg again “interrupted and said his account was ‘factually not correct.'” The Middle East Eye writes that the exchange was then “cut short when Milberg said she was being told they had to wrap up the interview.”* Turning to Texas, NOTUS reports Democratic Senate nominee James Talarico – capitalizing on the acrimonious primary battle between sitting Republican Senator John Cornyn and his victorious primary opponent Texas AG Ken Paxton – has taken the extraordinary step of bringing a Cornyn aide onto his campaign. According to this piece, “Jacob Smith, who worked for Cornyn for five years as a deputy legislative director and policy adviser, is taking on the role of deputy policy director for Talarico's campaign.” In a statement, Smith said that he is “proud” to join Talarico's campaign and that “Instead of playing partisan politics, Talarico speaks to the needs of everyday people who day in and day out work too hard for too little.” Smith also laid into Paxton, calling him “the most corrupt, self-dealing politician in Texas who would sell their futures to the highest contributor just to hold onto power,” and urging “fellow Republicans who know Ken Paxton is unfit to serve in the Senate to finally hold him accountable at the ballot box.” This piece quotes an anonymous “Republican operative” who characterized this kind of “cross-party hire” as “unheard of.” He added that Talarico has a “better chance than any Democrat has had in the state in a very long time.”* In more primary news, last week we discussed the victory of former Hartford, Connecticut Mayor Luke Bronin over 14-term incumbent Congressman John Larson. That same day, the Lever published an exposé of Stephen Mandel, a Connecticut-based billionaire hedge fund manager and Democratic mega-donor who is the “largest bankroller of a nascent political machine promising to ‘redefine' the Democratic Party.” Via two organizations – Majority Democrats and the Bench – Mandel and his wife have funneled tens of millions of dollars to candidates of their choosing in an attempt to form a “new [political] center.” According to this report, Bronin amassed a “sizable war chest,” during his primary challenge against Larson, much of which traces back to Mandel. Not only that, apparently, Bronin “used to be on the payroll of a nonprofit funded by the billionaire,” and his campaign's policy stances reflect the network's preferences and priorities. The Lever notes that, perhaps unsurprisingly, the Mandels did not return their requests for comment.* In more Connecticut news, in the wake of Larson's defeat, local media is beginning to question whether Senator Richard Blumenthal should run for another term in 2028, with WTNH noting that he will be 82 at the end of his current term. While Blumenthal has not formally announced that he will run for a fourth senate term, he did confirm that he has a campaign committee and it is raising money. This piece notes that Blumenthal is the second oldest member of Connecticut's congressional delegation, behind only Congresswoman Rosa DeLauro, 83, who represents the state's third congressional district. With the increased scrutiny on aging Democrats, and donors like Stephen Mandel bankrolling primary challenges by younger candidates, Blumenthal's decision of whether or not to run or anoint a successor could prove critical. For his part, Blumenthal is quoted saying “Age is a state of mind…and I am very, very happy doing my job right now, as energetically as I feel is appropriate.”* Senator Blumenthal features prominently in another story this week from a different part of Washington. NOTUS reports that on K Street, lobbyists for the defense industry – literally the military industrial complex – are “girding for aggressive investigations of President Donald Trump's Pentagon and the companies that do business with it,” if the Democrats retake one or both houses of Congress in the midterm elections. This piece emphasizes that Democrats have “spent two years seething that the Trump administration shut Congress out of decisions about the Pentagon, from the Iran war to politically connected contractors and a defense budget that's ballooned to $1.5 trillion.” Lobbyists are reported to be particularly wary of their clients being caught between outraged congressional Democrats and an uncooperative White House for the next two years. Blumenthal, the top Democrat on the Senate Investigations Subcommittee, is already zeroing in on 1789 Capital, where Donald Trump Jr. is an investor, and American Ventures, where Eric Trump is an investor, both of which received billions of dollars in government awards. He is quoted saying “We need to look into whether Trump's sons are profiting from investments in defense contractors that involve insider information or contracts awarded in ways that compromise defense interests.” Other investigations he signaled they might pursue include a probe of “the administration's growing reliance on single-source contracts and whether the administration has given preferential treatment to companies with political ties, particularly those that donated to Trump's White House ballroom project.” In the House, Democrats on the Armed Services Committee will likely focus on “military strategy, acquisition decisions and the Pentagon's rapidly growing budget,” while the Oversight Committee, is more focused on “corruption, conflicts of interest, companies connected to Trump allies such as SpaceX and other ethics issues.” When Republicans won control of the House, Senate, and presidency in 2024, many lobbying firms axed their Democratic staff. It seems they are beginning to regret that decision.* Our next two stories have to do with the AI boom. First, in Wisconsin, the politics of AI data centers have come to in large part define the ongoing race to succeed Democrat Tony Evers as Governor. DSA-backed candidate Francesca Hong rode her vow of a moratorium on new data center construction to front-runner status in the primary, only to lose by a hair to Evers' last minute chosen successor, David Crowley. Since becoming the nominee, Crowley has refused to adopt Hong's signature issue and his opponent, Republican Congressman Tom Tiffany is taking full advantage. According to Wisconsin Public Radio, Tiffany's campaign has released a new TV ad labeling his opponent “data center David Crowley.” In the ad, Crowley is “seen saying Wisconsin has the opportunity to be ‘an AI and a data hub not only for the entire country, but for the entire globe.'” Ironically, Tiffany himself has cast “pro-data center votes in Congress” and Crowley's campaign argues that Tiffany “wouldn't be as hard on developers as his campaign claims,” though he is now campaigning on “ending state subsidies for data centers and creating additional protections for ratepayers and the state's farmland and water.”* Next, a stunning feat of reporting by 404 Media exposed how “Amazon is buying massive quantities of books, scanning them for AI training data, and destroying them in the process.“ To investigate this, the outlet placed a tracking device in a rare book that they suspected would be acquired by an AI company for training data. Then, when indeed it was, they followed the book around the country to its final destination – an Amazon warehouse in Las Vegas, Nevada – where employees say that “all [they] do is scan books..Some are assigned to cut books, and others go to receive where they get books and scan the bar codes.” The printed book is destroyed in the process. The logo of the Amazon team that works at this warehouse, called VGT3, is a dinosaur, brandishing its teeth and with a book in its hands. The piece notes that the AI company Anthropic has previously been sued for engaging in the practice of destroying rare books in order to feed them into their large language models, or LLMs, on copyright grounds, but the “judge in the lawsuit ruled it was fair use and not a copyright violation for Anthropic to scan a book for training data in part because it destroyed the original, printed copy.” The author of this piece notes that these rare books are not necessarily monetarily valuable – they could be rare because “not many copies of them were ever printed,” or “they are in a foreign language not many people speak.” Still, as one bookseller said “There are different types of value…[besides monetary value] There's historical value, intellectual value, sentimental value. All sorts of things, and all of those the AI companies don't care about. They just want the content as a bunch of words strung together.”* Finally, we turn to the Vatican, where, Drop Site reports, Pope Leo XIV is using his pulpit to call for the opening of humanitarian corridors for civilians in Sudan. In his weekly Angelus address, the first American Pope highlighted “the plight of civilians in the besieged city of el-Obeid.” In addition to his call for humanitarian corridors, the pontiff called for both sides to “cease attacks on civilian targets.” Drop Site explains that El-Obeid, the largest city in Kordofan – the region comprising central Sudan – has faced intense drone attacks as the rebels of the Rapid Support Forces (RSF) battle the Sudanese army for supremacy in the region. An RSF siege has “left over 500,000 people in famine conditions for months and without supplies.” The United Nations warns that if El-Obeid falls, it could follow in the mold of el-Fasher, which fell to the RSF last year and resulted in “mass ethnic cleansing massacres by the RSF that killed an estimated 60,000 people.” We can only hope that the world will heed the Pope's plea for peace and humanitarian assistance to the civilian population of Sudan.This has been Francesco DeSantis, with In Case You Haven't Heard. Get full access to Ralph Nader Radio Hour at www.ralphnaderradiohour.com/subscribe

Boundless Body Radio
SPECIAL EPISODE! The Heritage Series with Metabolic Cancer Expert Dr. Thomas Seyfried! 1025

Boundless Body Radio

Play Episode Listen Later Aug 21, 2026 64:55


Send us Fan MailToday we're releasing a new episode from a brand new series called the Boundless Body Radio Heritage Series! I wanted to do something extra special to celebrate 1,000 podcast episodes recorded here at Boundless Body Radio, a milestone that we hit on June 24, 2026!These episodes are actually not new, although they might be new to you! When we first got started back in October, 2020, I was so fortunate that so many incredible people said "YES" to being hosted on the show, however, we didn't have very many listeners at the time!Today, we get thousands of downloads every single month, and are usually included in the top 150 Fitness and Nutrition Podcasts on the Apple Podcast charts!To honor our amazing guests, I will be selecting one of those original episodes and posting them here on for this special series!As I was going through these episodes again, I remembered how valuable these conversations actually were. it was really striking how much the information these experts have shared has born out to be even more accurate several years later.The audio quality of a show was not as good back then as it is now, but I still really hope you enjoy these episodes, and find them relevant and helpful to you today!Cheers, thanks as always for listening, and I really hope you enjoy this episode of the Boundless Body Radio Heritage Series!Dr. Thomas Seyfried is a returning guest on our show! Be sure to check out his first appearance on Boundless Body Radio on episode 60, which one of the most fascinating discussions we've ever had, all about cancer as a metabolic disease! He was also hosted on episode 363 of our podcast.Thomas N. Seyfried received his Ph.D. in Genetics and Biochemistry from the University of Illinois, Urbana, in 1976. He was a Postdoctoral Fellow in the Department of Neurology at the Yale University School of Medicine and then served on the faculty as an Assistant Professor in Neurology. Other awards and honors have come from such diverse organizations as the American Oil Chemists Society, the National Institutes of Health, The American Society for Neurochemistry, the Ketogenic Diet Special Interest Group of the American Epilepsy Society, the Academy of Comprehensive and Complementary Medicine, and the American College of Nutrition.Dr. Seyfried has over 150 peer-reviewed publications and is the author of the book, Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer (Wiley, 1st ed., 2012).Find Dr. Seyfried at-https://foundationformetaboliccancertherapies.com/Movie, coming soon- CANCERREVOLUTION: A Cancer Science Documentary with Dr. Seyfried and former podcast guest Travis Christofferson.Find Boundless Body at-myboundlessbody.comFind Boundless Body at-myboundlessbody.comBook a session with us here! 

Behind The Knife: The Surgery Podcast
Operative Standards for Cancer Surgery Series: Liver Resection for Hepatocellular Carcinoma

Behind The Knife: The Surgery Podcast

Play Episode Listen Later Aug 20, 2026 28:55


This mini-series on Behind the Knife will delve into the technical aspects of the Operative Standards for Cancer Surgery, developed through the American College of Surgeons Cancer Research Program. This third episode highlights the Hepato-Pancreato-Biliary cancer operative standard.Hosts:Eliza W. Beal, MD, FACS (X: @ElizaWBealMD) is a Hepato-Pancreato-Biliary surgeon at the Barbara Ann Karmanos Cancer Institute in Detroit. She is also an associate professor of Oncology and Surgery at Wayne State University School of Medicine.Morgan Jackson, MD is a general surgery resident at the Detroit Medical Center and Wayne State University in Detroit, MI.Daniel Nelson, MD, FACS, FSSO (X: @DWNelsonHPB) is a Hepato-Pancreato-Biliary surgeon at the University of Tennessee Health Science Center - Chattanooga.Hop Sanderson Tran Cao, MD, FACS (X: @HopSTranCao) is a Hepato-Pancreato-Biliary surgeon at MD Anderson Cancer Center. Guest:Alice Wei, MD is a Hepato-Pancreato-Biliary surgeon at Memorial Sloan Kettering and associate professor of surgery at Weill Cornell School of Medicine. Dr. Wei contributed to the development of the operative standards for HPB surgery. Learning Objectives: The goals of this podcast are to provide education about the standards, generate discussion, and offer technical pearls to both oncologic specialists and general surgeons, to all of whom these standards apply. In this podcast we discuss the operative standards for liver resection for hepatocellular carcinoma, which includes that the surgeon should: (1) perform a thorough inspection of the liver and abdomen, either laparoscopically or open, including performing liver ultrasound, and (2) should resect all lesions to macroscopically negative margins, preferably with an anatomic resection. Our guest Dr. Wei also provides technical tips, pearls for improving skills performing and interpreting liver ultrasound, and discusses the role of lymphadenectomy in patients with hepatocellular carcinoma. References: Operative Standards for Cancer Surgery, Volume 3: Sarcoma, Adrenal, Neuroendocrine, Peritoneal, Urothelial, Hepatobiliary https://www.facs.org/quality-programs/cancer-programs/cancer-surgery-standards-program/operative-standards-for-cancer-surgery/purchase/ Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more.  If you liked this episode, check out our recent episodes here: https://behindtheknife.org/listenBehind the Knife Premium: https://behindtheknife.org/premiumOral Board Review: https://behindtheknife.org/oral-boardOral Board Simulator: https://behindtheknife.org/oral-board/simulatorGeneral Surgery Oral Board Review Course: https://behindtheknife.org/premium/general-surgery-oral-board-reviewTrauma Surgery Video Atlas: https://behindtheknife.org/premium/trauma-surgery-video-atlasDominate Surgery: A High-Yield Guide to Your Surgery Clerkship: https://behindtheknife.org/premium/dominate-surgery-a-high-yield-guide-to-your-surgery-clerkshipDominate Surgery for APPs: A High-Yield Guide to Your Surgery Rotation: https://behindtheknife.org/premium/dominate-surgery-for-apps-a-high-yield-guide-to-your-surgery-rotationVascular Surgery Oral Board Review Course: https://behindtheknife.org/premium/vascular-surgery-oral-board-reviewColorectal Surgery Oral Board Review Course: https://behindtheknife.org/premium/colorectal-surgery-oral-board-reviewSurgical Oncology Oral Board Review Course: https://behindtheknife.org/premium/surgical-oncology-oral-board-reviewCardiothoracic Oral Board Review Course: https://behindtheknife.org/premium/cardiothoracic-surgery-oral-board-reviewOBGYN Oral Board Review Coures: https://behindtheknife.org/course/obgyn-oral-board-reviewEPA Playbook: https://behindtheknife.org/course/epa-playbookSurgical Instrument Flashcards: https://behindtheknife.org/course/surgical-instrument-flashcardsABSITE Review: https://behindtheknife.org/course/absite-2026-exam-reviewDownload our App:Apple App Store: https://apps.apple.com/us/app/behind-the-knife/id1672420049Android/Google Play: https://play.google.com/store/apps/details?id=com.btk.app&hl=en_US

Associations Thrive
191. Angela Davis, CEO of SPR and Yasmeen Fields, CEO of SBI, on Becoming Independent, Association Autonomy, and the Power of Executive Peer Networks

Associations Thrive

Play Episode Listen Later Aug 20, 2026 28:55


What happens when the organization that has managed your association for decades tells you that you have 18 months to find a new path forward? How can association leaders navigate a major operational transition while protecting their staff, serving members, and making smart decisions about what to keep in-house and what to outsource?In this episode of Associations Thrive, host Joanna Pineda interviews Angela Davis, CEO of the Society for Pediatric Radiology (SPR), and Yasmeen Fields, CEO of the Society of Breast Imaging (SBI). Angela and Yasmeen discuss:How SPR is a community of more than 3,000 physicians, trainees, and allied professionals dedicated to improving children's health through medical imaging, while SBI represents more than 4,200 breast imaging radiologists working to minimize breast cancer mortality and suffering.Why radiology has so many subspecialty associations. As Angela explains, “children are not small adults,” and specialized areas such as pediatric radiology and breast imaging require distinct expertise, education, and professional communities.How both SPR and SBI were managed for decades by the American College of Radiology (ACR), which provided the infrastructure, resources, expertise, and operational support that allowed smaller specialty societies to grow and thrive.How ACR ultimately decided to focus exclusively on its own mission, strategic plan, and members, giving the societies it managed 18 months to transition to a new management structure.How SPR and SBI evaluated different business models, including partnering with another radiology organization, working with an association management company (AMC), and becoming fully self-managed. Both initially partnered with AMCs before ultimately becoming standalone organizations.How becoming independent required Angela and Yasmeen to assume responsibility for functions that previously existed under the ACR umbrella, including HR, accounting, technology, investments, and operational decisions.How both organizations learned not to overcommit during a major transition. Today, both organizations combine small internal staffs with strategic outsourced support.How collaboration extends across the larger “House of Radiology.” Through gatherings like the ACR Inter-Society Conference, association executives and volunteer leaders learn from one another, develop stronger relationships, and see how their individual organizations fit into the broader radiology community.References:SBI WebsiteSPR Website

The Grimerica Show
#776 - Helen Lavretsky, MD, MS - Living From The Soul: The Neuroscience of Spiritual Awakening

The Grimerica Show

Play Episode Listen Later Aug 19, 2026 89:37


Interview starts at 27:10   The neuroscience of spiritual awakening, how Kundalini yoga shaped her life, and why she believes listening inward is especially important in a time of cultural confusion. She also explains how her work in geriatric psychiatry connects spirituality, brain health, stress regulation, and prevention strategies for aging populations. Helen Lavretsky, MD, MS, is a Professor In-Residence in the Department of Psychiatry at UCLA (Semel Institute for Neuroscience and Human Behavior), a leading geriatric integrative psychiatrist, and a pioneer in mind-body approaches to late-life mental health. https://drhelenlavretsky.com/book/living-from-the-soul/ https://drhelenlavretsky.com/about/   In this episode: Dr. Helen Lavretsky shares her unusual path from the former Soviet Union into psychiatry, neuroscience, and later Kundalini yoga teacher training. She explains how growing up in an atheist Soviet environment still left room for underground spirituality passed through families and oral tradition. She describes a six-month temporary enlightenment experience after Kundalini practice and why it was physically intense, hard to describe, and initially unsustainable. The conversation focuses on her book Living from the Soul and the idea that people are increasingly being pushed to trust their own wisdom instead of outside authorities. She discusses how spirituality shows up in geriatric psychiatry, especially for older adults, dementia caregivers, and long COVID patients dealing with mortality and stress. She argues that meditation, breathing practices, yoga, tai chi, and qigong can improve self-regulation, brain health, and decision-making under pressure. She outlines how brain health should be cultivated across the lifespan, starting in childhood and even in utero, rather than only addressed later in life. She notes that lifestyle factors such as sleep, movement, diet, and stress management matter for dementia prevention and broader cognitive resilience. She emphasizes that meaning, purpose, and connection to soul are central to mental well-being. Key frameworks: Soul-based self-inquiry- asking inwardly what is right for you rather than defaulting to external authority Brain health across the lifespan- prevention beginning in childhood and even before birth Stress self-regulation toolkit- breathing, meditation, yoga, tai chi, and qigong as practical nervous-system supports Constitutional approach to diet- different people may need different foods based on ancestry, metabolism, and predisposition   Become a Lord or Lady with 1k donations over time. And a Noble with any donation. Leave Serfdom behind and help Grimerica stick to 0 ads and sponsors and fully listener supported. Thanks for listening!! Help support the show, because we can't do it without ya. http://www.grimerica.ca/support Secret Teachings Esoteric Book Club audiobook library. www.skool.com/audiobooks Pegs and Jokers - Card and peg boardgame online for free https://pegsandjokers.ca/ https://www.simulationmaps.com/#products Suite of Interactive Maps! DisasterMap, VolcanoSim, AsteroidSim, ShipwreckMap, UFOMap etc https://www.amazon.com/Unlearned-School-Failed-What-About/dp/1998704904/ref=sr_1_3?sr=8-3   Support the show directly: https://open.spotify.com/show/2punSyd9Cw76ZtvHxMKenI?si=ImKxfMHgQZ-oshl499O4dQ&nd=1&dlsi=4c25fa9c78674de3 Watch or Listen on Spotify https://grimericacbd.com/ CBD / THC Gummies and Tinctures https://www.patreon.com/grimerica http://www.grimericaoutlawed.ca/support   Our audio book website: www.adultbrain.ca Check out our next trip/conference/meetup - Contact at the Cabin www.contactatthecabin.com www.grimerica.ca/shrooms and Micro Dosing Darren's book www.acanadianshame.ca Join the chat / hangout with a bunch of fellow Grimericans Https://t.me.grimerica grimerica.ca/chats   Discord Chats https://itunes.apple.com/ca/podcast/grimerica-outlawed Sign up for our newsletter https://grimerica.substack.com/ SPAM Graham = and send him your synchronicities, feedback, strange experiences and psychedelic trip reports!! graham@grimerica.com Purchase swag, with partial proceeds donated to the show: www.grimerica.ca/swag Send us a postcard or letter http://www.grimerica.ca/contact/ Episode ART - Napolean Duheme's site http://www.lostbreadcomic.com/ MUSIC https://brokeforfree.bandcamp.com/ - Something Galactic Felix's Site sirfelix.bandcamp.com - Should I       Timestamps: (00:00) Technical start and introducing Dr. Helen Lavretsky and her new book (01:15) Helen's background in geriatric psychiatry and the science-spirituality bridge (02:45) Growing up in the Soviet Union and an early attraction to psychiatry (03:59) First Kundalini yoga experience and the start of her spiritual-scientific merger (05:25) Death, dying, and why mortality became a lifelong theme in her work (06:10) Lanai, early Kundalini practice, and rapid changes in health and temperament (07:35) Temporary enlightenment and the difficulty of describing spiritual states (09:59) Why she wrote the book and how the world is changing around spirituality (12:27) Crumbling old structures and learning to depend on inner wisdom (14:14) What happens when spirituality is suppressed in the Soviet system (16:55) The shift from religion to spirituality, atheism, and changing belief patterns (19:07) Why the soul matters and how her meditation work helps people connect (21:24) How to tell soul guidance apart from self-talk and mental noise (22:29) Family reactions, including her mother's skepticism (23:27) Atheism as a spiritual belief system and its place on the spectrum (25:00) Materialism, duality, and the limits of studying non-material experience (27:35) Meaning and purpose as measures of spirituality (28:09) Yoga, tai chi, and stress regulation in aging and chronic illness (30:04) Staying calm during the Los Angeles fires while teaching breathing practices (31:06) Yoga, cognition, gray matter, and reducing inflammation (32:03) Young people, social media, the pandemic, and declining resilience (35:11) Prevention strategies for Alzheimer's and dementia starting in midlife (36:36) Brain health across the lifespan, including early childhood and in utero (38:30) Simple breathing tools kids can learn for resilience and self-regulation (39:39) Dementia, Alzheimer's, cholesterol, and lifestyle factors (41:19) Why there is no magical one-food cure and why sardine-fasting is not a silver bullet (43:15) The Mediterranean diet, processed foods, seed oils, and nuts (47:18) Supplements she uses for brain health, including B vitamins, vitamin D, fish oil, ginkgo, and adaptogens (49:51) Ancestry, blood type, constitution, and why one diet does not fit everyone (52:24) Local food, microbiome health, and eating in tune with your environment (53:18) What the book covers beyond spirituality: trauma, psychedelics, technology, and authenticity (55:22) Why she wants people to ask their own intuition instead of outsourcing authority (56:30) Where to find her book and follow her work       Dr. Helen Lavretsky is a Professor In-Residence in the Department of Psychiatry at UCLA and a geriatric integrative psychiatrist with federally funded research program in geriatric depression and integrative mental health using mind-body interventions. She directs a clinical and research program in Integrative Psychiatry. She is a recipient of the Career Development award from the NIMH and the NCCIH, and the recipient of the 2020 Distinguished Investigator awards for research in geriatric psychiatry from the American College of Psychiatrists and the American Association for Geriatric Psychiatry, and the Jack Weinberg Memorial Award in Geriatric Psychiatry from the American Psychiatric Association. She is the Distinguished Life Fellow of the American Psychiatric Association, the Distinguished Fellow of the American Association for Geriatric Psychiatry, and the Fellow of the American College of Neuropsychopharmacology. She is the President of the American Association for Geriatric Psychiatry.

Cardionerds
463. Multimodality Imaging in Chronic Coronary Artery Disease with Dr. Panithaya Chareonthaitawee

Cardionerds

Play Episode Listen Later Aug 17, 2026 39:49


CardioNerds (Drs. Dr. Natalie Marrero, Dr. Ritika Tuli, and Dr. Rafael Toro Manotas) discuss multimodality imaging for risk stratification, evaluation, and management of chronic coronary artery disease with Dr. Panithaya Chareonthaitawee. Audio editing by CardioNerds intern Iman Razeghian. This episode was produced as part of the CardioNerds Academy curriculum by House Taussig under the guidance of House Chief, Dr. Natalie Marrero and Academy Program Director, Dr. Gurleen Kaur. A matching review article will be published in US Cardiology Review, the official journal of CardioNerds. This discussion was planned in collaboration with the Mayo Clinic Cardiovascular Board Review Course. In this episode, we discuss the pathophysiology and risk stratification of chronic coronary artery disease (CAD), as well as the current landscape of non-invasive evaluation of this condition. CAD remains a leading cause of morbidity and mortality despite advances in pharmacological and non-pharmacological strategies for the prevention and treatment of atherosclerotic disease. The concept of chronic CAD has shifted from the traditional model of stable, obstructive, flow-limiting disease, toward the current understanding of a dynamic process that extends beyond obstructive epicardial lesions to include non-obstructive plaque, diffuse atherosclerosis, and microvascular disease. Similarly, the imaging modalities used to evaluate CAD have evolved, and clinicians now have an extensive menu of options, each with distinct advantages and limitations, that must be selected carefully to maximize diagnostic accuracy and optimize treatment guidance, while also considering resource availability, local expertise, and high-value care. By the end of the episode, listeners will understand the pathophysiology of chronic CAD, risk-stratify patients with suspected CAD, recognize the advantages and pitfalls of each non-invasive diagnostic modality, and select the most appropriate diagnostic tool for a given clinical scenario. Enjoy this Circulation 2022 Paths to Discovery article to learn about the CardioNerds story, mission, and values. CardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Pearls: Chronic CAD is a complex process that extends beyond obstructive epicardial stenosis to include non-obstructive disease, dynamic plaque burden and ischemia, diffuse atherosclerosis, microvascular dysfunction, vasospasm, among others. When evaluating patients with suspected CAD, the diagnostic process should be guided by a specific and appropriate clinical question before ordering any tests. The current diagnostic tool arsenal is broadly divided into anatomic and functional imaging modalities. These are complementary, each with distinct properties and limitations, addressing different clinical questions and assessing different aspects of disease. Local availability and expertise, along with patient-specific considerations and contraindications, determine the choice of diagnostic modality. No single test is best for every patient. INOCA and coronary microvascular dysfunction represent a common and increasingly recognized entity that is diagnosable and treatable; initial evaluation includes non-invasive testing such as stress PET and stress CMR. References Gulati M, Levy PD, Mukherjee D, et al. 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guideline for the Evaluation and Diagnosis of Chest Pain: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation. 2021;144(22):e368-e454. doi:10.1161/CIR.0000000000001029 https://pubmed.ncbi.nlm.nih.gov/34709879/ Vrints C, Andreotti F, Koskinas KC, et al. 2024 ESC Guidelines for the management of chronic coronary syndromes. Eur Heart J. 2024;45(36):3415-3537. doi:10.1093/eurheartj/ehae177 https://pubmed.ncbi.nlm.nih.gov/39210710/ Virani SS, Newby LK, Arnold SV, et al. 2023 AHA/ACC/ACCP/ASPC/NLA/PCNA Guideline for the Management of Patients With Chronic Coronary Disease: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines. Circulation. 2023;148(9):e9-e119. doi:10.1161/CIR.0000000000001168 https://pubmed.ncbi.nlm.nih.gov/37471501/ Edvardsen T, Asch FM, Davidson B, et al. Non-Invasive Imaging in Coronary Syndromes: Recommendations of The European Association of Cardiovascular Imaging and the American Society of Echocardiography, in Collaboration with The American Society of Nuclear Cardiology, Society of Cardiovascular Computed Tomography, and Society for Cardiovascular Magnetic Resonance. J Am Soc Echocardiogr. 2022;35(4):329-354. doi:10.1016/j.echo.2021.12.012 https://pubmed.ncbi.nlm.nih.gov/35379446/ Douglas PS, Hoffmann U, Patel MR, et al. Outcomes of anatomical versus functional testing for coronary artery disease. N Engl J Med. 2015;372(14):1291-1300. doi:10.1056/NEJMoa1415516 https://pubmed.ncbi.nlm.nih.gov/39210710/ Sharma A, Coles A, Sekaran NK, et al. Stress Testing Versus CT Angiography in Patients With Diabetes and Suspected Coronary Artery Disease. J Am Coll Cardiol. 2019;73(8):893-902. doi:10.1016/j.jacc.2018.11.056 https://pubmed.ncbi.nlm.nih.gov/30819356/ SCOT-HEART Investigators, Newby DE, Adamson PD, et al. Coronary CT Angiography and 5-Year Risk of Myocardial Infarction. N Engl J Med. 2018;379(10):924-933. doi:10.1056/NEJMoa1805971 https://pubmed.ncbi.nlm.nih.gov/30145934/ Li Z, Xu T, Wang Z, et al. Prognostic Significance of Computed Tomography-Derived Fractional Flow Reserve for Long-Term Outcomes in Individuals With Coronary Artery Disease. J Am Heart Assoc. 2025;14(2):e037988. doi:10.1161/JAHA.124.037988 https://pubmed.ncbi.nlm.nih.gov/39791423/ Bateman TM, Al-Mallah MH, et al. Clinical indications for positron emission tomography myocardial perfusion imaging and myocardial blood flow quantification: An American Society of Nuclear Cardiology position statement. J Nucl Cardiol. 2026;57:102619. doi:10.1016/j.nuclcard.2025.102619 https://pubmed.ncbi.nlm.nih.gov/41482140/ Taqueti VR, Di Carli MF. Coronary Microvascular Disease Pathogenic Mechanisms and Therapeutic Options: JACC State-of-the-Art Review. J Am Coll Cardiol. 2018;72(21):2625-2641. doi:10.1016/j.jacc.2018.09.042 https://pubmed.ncbi.nlm.nih.gov/30466521/ Taqueti VR, Hachamovitch R, Murthy VL, et al. Global coronary flow reserve is associated with adverse cardiovascular events independently of luminal angiographic severity and modifies the effect of early revascularization. Circulation. 2015;131(1):19-27. doi:10.1161/CIRCULATIONAHA.114.011939 https://pubmed.ncbi.nlm.nih.gov/25400060/ Mehta PK, Huang J, Levit RD, Malas W, Waheed N, Bairey Merz CN. Ischemia and no obstructive coronary arteries (INOCA): A narrative review. Atherosclerosis. 2022;363:8-21. doi:10.1016/j.atherosclerosis.2022.11.009 https://pubmed.ncbi.nlm.nih.gov/36423427/ Kunadian V, Chieffo A, Camici PG, et al. An EAPCI Expert Consensus Document on Ischaemia with Non-Obstructive Coronary Arteries in Collaboration with European Society of Cardiology Working Group on Coronary Pathophysiology & Microcirculation Endorsed by Coronary Vasomotor Disorders International Study Group. EuroIntervention. 2021;16(13):1049-1069. doi:10.4244/EIJY20M07_01 https://pubmed.ncbi.nlm.nih.gov/32624456/

Boardroom Governance with Evan Epstein
Shannon Nash: Boards, AI Agents, and Human Judgment

Boardroom Governance with Evan Epstein

Play Episode Listen Later Aug 17, 2026 55:00


(0:00) About the Boardroom Governance Summit (Aug 26-27, 2026)  (0:43) Intro (2:08) About the podcast sponsor: The American College of Governance Counsel. (2:54) Start of interview.  (3:56) Origin Story of Shannon Nash (7:00) Her pivot from Law to Finance (9:15) Her operating and finance career  (12:55) Her experience in tech (subscription businesses) and current COO and CFO role at Vibrant Planet (15:50) Her first board (UserTesting) and subsequent board career (Netscout, SoFi, Lazy Dog Restaurants, Silicon Valley Community Foundation)  (22:04) Cybersecurity Meets AI (28:47) Where are the Humans? The next wave in the agentic era (31:44) Regulated Boards and Risk (36:25) Private Board Experience (VC and PE).  (41:13) About Alpha AI, focusing on AI Governance (43:53) On her podcast No Boxes, Just Verses (46:45) Her obsession with the Acquired podcast (47:41) Her mentors (49:40) Quotes that she thinks of often or lives her life by. (51:06) An unusual habit or an absurd thing that she loves. Beat Shazam show (52:15) The living person she most admires. Shannon Nash is a qualified financial expert, attorney, and CPA with over 30 years at the intersection of technology, finance, and governance. She serves as a board member in both public and private companies. You can follow Evan on social media at:X: @evanepsteinLinkedIn: https://www.linkedin.com/in/epsteinevan/ Substack: https://evanepstein.substack.com/__To support this podcast you can join as a subscriber of the Boardroom Governance Newsletter at https://evanepstein.substack.com/__Music/Soundtrack (found via Free Music Archive): Seeing The Future by Dexter Britain is licensed under a Attribution-Noncommercial-Share Alike 3.0 United States License

The mindbodygreen Podcast
663: Daily choices that shape brain health in your 30s, 40s & beyond | David Perlmutter, MD

The mindbodygreen Podcast

Play Episode Listen Later Aug 16, 2026 47:20


“We can choose our brain's destiny,” says David Perlmutter, MD. Perlmutter is a Board-Certified Neurologist and six-time New York Times bestselling author whose work focuses on the intersection of neurology, nutrition, and brain health. He is on the Board of Directors of the American College of Nutrition and the Editorial Board of the Journal of Alzheimer's Disease. His books, including the #1 bestseller Grain Brain, has been published in 32 languages and sold over a million copies. Perlmutter lectures globally at leading institutions and has been featured on major media outlets including 20/20, CNN, The Today Show, and Oprah. His new book, Brain Defenders, focuses on the pivotal role of microglia, the brain's immune cells, in protecting, repairing, and reprogramming the brain for lifelong resilience, and is now available for pre-order. 00:00 - Treating the symptoms, not the cause  02:37 - Microglial cells & their evil twin state  05:44 - How metabolism affects the brain  08:00 - Gut bacteria, inflammation, & brain degeneration  11:38 - Why lifestyle beats the APOE4 gene  16:25 - Perlmutter's daily routine 23:55 - Loneliness & oxytocin  26:21 - The effects of long COVID on the brain 32:18 - Glyphosate & other environmental factors  39:20 - Reprogramming microglia & mitochondrial transplants  41:35 - Own your brain's destiny Referenced in the episode:  For more about Perlmutter, visit his website: https://drperlmutter.com/  Alzheimers & UPFs study: https://doi.org/10.1016/j.tjpad.2024.100042  POINTER study - https://jamanetwork.com/journals/jama/fullarticle/2837046  20-week Alzheimer's study:  https://link.springer.com/article/10.1186/s13195-024-01482-z  Golf course & Parkinson's study: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2833716  We hope you enjoy this episode, and feel free to watch the full video on YouTube! Whether it's an article or podcast, we want to know what we can do to help here at mindbodygreen. Let us know at: podcast@mindbodygreen.com. Learn more about your ad choices. Visit megaphone.fm/adchoices

All Shows Feed | Horse Radio Network
My Senior Horse 51: Vision with Dr. Ann Dwyer

All Shows Feed | Horse Radio Network

Play Episode Listen Later Aug 15, 2026 29:44


Dr. Ann Dwyer, an equine practitioner and veterinary leader for nearly 40 years prior to retirement, discusses equine vision loss and management of blind horses. She has a special interest in equine vision, and she was named an honorary member of the American College of Veterinary Ophthalmology.My Senior Horse - Episode 51 Guests and Links:Guests: Dr. Ann Dwyer, Honorary Member of the American College of Veterinary OphthalmologyConnect with Host: Kimberly S. Brown of Editorial Director of My Senior Horse | Email Kim (kbrown@equinenetwork.com) | Follow Kim on LinkedIn (@kimberlylsbrown)

5 Things
Why hundreds of private American colleges are shutting down

5 Things

Play Episode Listen Later Aug 13, 2026 14:29


When Vermont's Sterling College shut down, it brought into focus a growing crisis for higher education in rural America. With hundreds of small private colleges facing severe financial pressure, what happens to the students and communities left behind? Investigative journalist Jon Marcus from The Hechinger Report joins The Excerpt for a look at the impacts and what families must look for prior to enrollment.Let us know what you think of this episode by sending an email to podcasts@usatoday.com. Episode transcript available here. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The Adversity Advantage
The Everyday Habits That Are Aging Your Brain | Dr. David Perlmutter

The Adversity Advantage

Play Episode Listen Later Aug 13, 2026 69:29


Dr. David Perlmutter is a Board-Certified Neurologist and six-time New York Times bestselling author whose work focuses on the intersection of neurology, nutrition, and brain health. A Fellow of the American College of Nutrition, he serves on its Board of Directors and on the Editorial Board of the Journal of Alzheimer's Disease. His books, including the #1 bestseller Grain Brain, have been published in 32 languages and sold over a million copies. Dr. Perlmutter lectures globally at leading institutions and has been featured on major media outlets including 20/20, CNN, The Today Show, and Oprah. His contributions have earned him numerous national and international awards for clinical innovation and leadership. Today on the show, we discuss why Alzheimer's may be driven more by lifestyle than genetics, how insulin resistance and blood sugar can quietly damage the brain, the foods and eating habits that may protect cognitive health, why sleep, exercise, and social connection are critical for preventing decline, what caffeine, nicotine, marijuana, and alcohol actually do to the brain, and the simple changes you can start making today to protect your memory for decades to come. Thank you to today's sponsor: Momentous Try Momentous Signature Spec Creatine: https://www.livemomentous.com Use code ADVERSITY for up to 35% off your entire first order Learn more about your ad choices. Visit megaphone.fm/adchoices

The Plaidcast
502. Plaidcast in Person from Spy Coast Farm- Dr. Michele Frazer, DVM, Berry Porter, & Eleanor Rudnicki

The Plaidcast

Play Episode Listen Later Aug 13, 2026 88:26


Send us Fan MailDr. Michele Frazer, DVM, is a board-certified equine veterinarian at Hagyard Equine Medical Institute in Lexington, Kentucky — one of the world's oldest and most respected equine veterinary practices — where she holds dual diplomate status in two of the most demanding specialties in veterinary medicine. A diplomate of both the American College of Veterinary Internal Medicine and the American College of Veterinary Emergency and Critical Care, Dr. Frazer represents the kind of deep, specialized expertise that the most complex equine cases demand. Her passion for horses and the equine industry was always present, but her specific desire to become an equine veterinarian crystallized in a memorable moment: watching Seattle Slew win the Triple Crown. From that spark, she built a career at the highest levels of equine medicine. Her professional interests center on neonatal medicine and the treatment and research of Lawsonia intracellularis, a bacterial pathogen that causes significant disease in young horses and remains an active area of veterinary research. Dr. Frazer describes her first week at Hagyard as her favorite memory of her veterinary career — a dream come true because of the people, the horses, and the extraordinary location in the heart of the Thoroughbred world. Outside of work, she is an enthusiastic supporter of the arts and shares her life with an impressive menagerie that includes horses, llamas, dogs, cats, saltwater fish, rabbits, and lizards.Berry Porter is one of the most respected and inspiring professionals in American hunter-jumper sport — a trainer, judge, volunteer leader, and community builder whose career is as much a story about what is possible in this sport as it is about what he has accomplished within it.Porter's introduction to the hunter-jumper world came through a pony ride as a young child in the Houston area — a single moment that set the course of his life. At 22, he attended his first hunter-jumper competition at the Great Southwest Equestrian Center in Katy, Texas, arriving without a groom — cleaning all the stalls himself, arriving at 3 or 4 am to do chores before stepping into his role as professional rider and trainer. That combination of humility and relentless work ethic has defined everything he has built since. Berry Porter is the head trainer at Brookside Pine Farms in Conroe, Texas, where he has developed many riders from the beginner level, progressing to compete in the collegiate ranks and succeed at the top levels of equestrian competition. He once watched Frank Madden, Stacia Klein Madden, Andre Dignelli, and Missy Clark on television and thought they were rock stars — and now has those same professionals on speed dial while his students go toe-to-toe with theirs at championship shows. His competitive accomplishments are substantial. At the 2025 Platinum Performance/USEF Show Jumping Talent Search Final — East, Porter took Leading Trainer honors after coaching riders Eleanor Rudnicki and Emily Jurnovoy to the top two finishes. His contributions to the governance of the sport are equally significant. Porter voluntarily serves on the USHJA Hunter Working Group and the Joint Equitation Task Force, and in December 2025 was awarded the USHJA President's Distinguished Service Award at the USHJA Evening of Equestrians — an honor bestowed upon members who have gone beyond the call of duty to bring the sport to a new level. In May 2026, he was named a recipient of the Ethos Award presented by Ethos Award Equestrian, Inc., which celebrates and elevates the contributions of Black and Brown equestrians who are creating meaningful change and inspiring a more inclusive future in the sport. Porter was among the initial members of the USHJA Diversity Task Force, formed in 2020, and has consistently approached conversations about race and access in equestrian sport with the levelheadedness, generosity, and fundamental optimism that characterize everything he does. Berry Porter is, in every sense, a professional whose presence in this sport makes it measurably better.Eleanor Rudnicki is one of the most compelling success stories in American hunter-jumper sport — a young professional from Conroe, Texas whose journey from a small local barn and a cart-bred pony to the winner's circle of the nation's most prestigious equitation finals is the kind of story the sport tells about itself at its best, and one she actually lived.Her start in the sport was far from glamorous. Growing up in Texas, she began at a small local barn with a pony originally bred to pull a cart — and that same pony, through hard work and persistence, carried her all the way to Pony Finals. The barn where she learned to ride focused primarily on jumpers, but Eleanor was drawn early and irrevocably to the hunters and equitation. She moved to Berry Porter's Brookside Pine Farm in Conroe, Texas at age twelve, and that partnership would prove to be the foundation of everything that followed.What distinguished Eleanor throughout her junior career was not just talent but an extraordinary ability to catch ride — to get on a horse she had barely met and produce a performance that looked like years of partnership. Many of the horses she rode were new to either the equitation or hunter ring, and she fell in love early with the experience of feeling their progression and growth. That versatility produced results across the country at the highest levels of junior competition. In 2019, she won the THIS National Children's Medal Final, and that same year emerged victorious in the Hamel Foundation National Horse Show 3'3" Equitation Championship — impressively, during her first year competing in the equitation ranks and her first indoors season, on a horse she had ridden for the first time only one week prior. She went on to win the ASPCA Maclay at the Kentucky Summer Horse Show and captured the Overall Grand Championship in the 3'6" Junior Hunter National Championship — West in 2023, earning scores of 90 across all three phases on a catch ride.The crowning achievement of her junior career came at the 2025 Platinum Performance/USEF Show Jumping Talent Search Finals — East, where she and Qwantreau, a 2016 Belgian Warmblood gelding, were crowned champions after navigating a technical 1.15m course featuring bending lines, unrelated distances, and an open water jump. The win made her the top finisher in one of the most coveted equitation-to-jumper transition competitions in the country and confirmed what the industry had known for years — that Eleanor Rudnicki was ready for whatever came next.Now competing as a professional, she manages horses, clients, and staff while transitioning into the open jumper ranks, with her sights set on five-star shows and ultimately the U.S. Equestrian Team. The cart pony from Texas has taken her a very long way, and she is just getting started.theplaidhorse.comThank you so much for joining us today on the Plaidcast. This podcast is a labor of love, and every single episode exists because of this incredible community of riders, trainers, barn managers, parents, and horse lovers who show up in the barn, in the ring, and right here with us.At The Plaid Horse, our commitment goes far beyond the show ring. We believe deeply in the power of literacy and education and that every rider, at every level, deserves access to knowledge, stories, and ideas that make them a better horseperson and a better human being. Reading matters. Learning matters. And the stories we tell each other in this sport matter more than we sometimes realize.Whether you are a junior rider picking up your first copy of The Plaid Horse  Magazine, a professional trainer looking for inspiration, or someone who simply loves horses and everything this world stands for then this community is for you. You belong here.We build this together. Every article, every episode, every conversation is an opportunity to learn something new, to feel less alone in the challenges of this sport, and to be reminded of why we fell in love with horses in the first place.Until next time, keep reading, keep learning, keep riding, and remember that the horse world is better when we build it together. I will see you at the ring!

Time to Transform with Dr Deepa Grandon
The Asthma Treatment Blind Spot No One Talks About (and How GLP-1s Can Help) w/ Dr. Atoosa Kourosh | Ep 59

Time to Transform with Dr Deepa Grandon

Play Episode Listen Later Aug 13, 2026 43:15


Asthma is often treated like a lung problem. The tighter the chest, the more inflamed the airway, the worse the flare-up, the answer has usually been to reach for medications designed to calm the lungs directly.But what if, for some patients, the real driver is not only in the lungs at all?For years, clinicians have recognized that patients with both obesity and asthma often experience a more difficult form of the disease. Their symptoms are more severe. Their flare-ups are more frequent. Their quality of life is lower. And frustratingly, many do not respond as well to the standard asthma therapies we rely on, including inhaled steroids.That is because obesity-related asthma is not simply “asthma plus extra weight.” It appears to be a distinct phenotype shaped by metabolic dysfunction, systemic inflammation, insulin resistance, immune reprogramming, and the mechanical effects of excess weight on lung function. In other words, for many patients, asthma may not be just a disease of the airways. It may be a whole-body inflammatory condition showing up in the lungs.That shift in thinking is why the growing research around GLP-1 receptor agonists is so compelling. These medications, originally developed for type 2 diabetes and now widely known for their role in weight management, may be doing far more than changing blood sugar or body weight. Emerging research suggests they may influence airway inflammation, immune signaling, airway smooth muscle function, and asthma exacerbation risk, sometimes even before major weight loss occurs.To explore what this could mean for the future of asthma care, Dr. Atoosa Kourosh, a board-certified allergist, immunologist, and pediatrician with more than two decades of clinical experience, returns to the show.She is the founder of Holistic Allergy and Immunology and chair of the Integrative Medicine Committee at the American College of Allergy, Asthma, and Immunology, where she brings together conventional medicine, lifestyle medicine, metabolic health, and integrative care.Together, we explore:Why obesity-related asthma is not just “regular asthma in a heavier body,” but a distinct phenotype with different biology, different inflammation, and often a different response to treatmentHow metabolic dysfunction, insulin resistance, adipokines, immune reprogramming, and systemic inflammation can all shape what happens in the lungsWhy standard asthma therapies may miss the mark for patients whose disease is driven less by classic allergic inflammation and more by metabolic inflammationWhat emerging research suggests about GLP-1 receptor agonists and their potential effects on airway inflammation, airway smooth muscle, bronchodilation, and asthma exacerbationsWhy some patients may see asthma improvement before significant weight loss, suggesting these medications may be acting on more than the scaleWhat real-world data can and cannot tell us about GLP-1 medications, asthma attacks, and patients with both asthma and type 2 diabetesWhy randomized controlled trials are still needed before GLP-1s can be considered a definitive asthma treatmentWhat clinicians and families should consider before using GLP-1 medications in adolescents, including growth, muscle loss, bone health, mental health, activity levels, and the need for careful testing and monitoringWhy these medications should be viewed as one tool in a broader lifestyle and integrative medicine toolkit, not a quick fix or a substitute for nutrition, movement, sleep, stress regulation, and anti-inflammatory livingHow this research could change the way we classify asthma in the future, moving from a lung-only model to a more metabolic, systems-based model of chronic inflammatory diseaseIf you are a clinician treating difficult-to-control asthma, a patient living with asthma and metabolic dysfunction, or someone trying to understand why chronic disease rarely fits into one neat category, this conversation will challenge you to look beyond the lungs and consider the whole body story.About the GuestDr. Atoosa Kourosh, MD, MPH, RYT, is a physician, board-certified in pediatrics, Allergy & immunology, and public health. She's also a patient health advocate, a Clinical Hypnotherapy practitioner, and a registered yoga teacher. Dr. Kourosh combines treatment modalities from cutting-edge and mainstream medicine with the best of functional and integrative medicine therapies and traditional philosophies to treat the whole person in their environment. She is the chair of the American College of Allergy, Asthma, and Immunology Integrative Medicine Committee and an internationally renowned expert in holistic and integrative health. Visit https://www.doctoratoosa.com/ to learn more.About Your HostHosted by Dr. Deepa Grandon, MD, MBA, a triple board-certified physician with over 23 years of experience working as a Physician Consultant for influential organizations worldwide. Dr. Grandon is the founder of Transformational Life Consulting (TLC) and an outspoken faith-based leader in evidence-based lifestyle medicine.ResourcesWork with Me - Learn More About My Soon-to-Launch Telemedicine PlatformExciting news—my virtual medical platform is launching soon! If you're looking for personalized, evidence-based care in allergy, immunology, and lifestyle medicine, stay tuned. Click here to join the wait-list and be the first to receive updates about services, membership options, and launch details.Precision care. Personalized guidance. Wherever you are.Feeling stuck and want guidance on how to transform your spiritual, mental and physical well being? Get access to Dr Deepa's 6 Pillars of Health video! Subscribe and watch the video for free here.Want to receive a devotional every week From Dr. Deepa? Devotionals are dedicated to providing you with a moment of reflection, inspiration, and spiritual growth each week, delivered right to your inbox. Subscribe now.Ready to deepen your understanding of trauma and kick start your healing journey? Explore a range of online and onsite courses designed to equip you with practical and affordable tools. From counselors, ministry leaders, and educators to couples, parents and individuals seeking help for themselves, there's a powerful course for everyone. Browse all the courses now to start your journey.Disclaimer​​TLC is presenting this podcast as a form of information sharing only. It is not medical advice or intended to replace the judgment of a licensed physician. TLC is not responsible for any claims related to procedures, professionals, products, or methods discussed in the podcast, and it does not approve or endorse any products, professionals, services, or methods that might be referenced.

The Lead Podcast presented by Heart Rhythm Society
The Lead Episode 164: A Discussion of Digital Twin–Guided Ablation for Ventricular Tachycardia

The Lead Podcast presented by Heart Rhythm Society

Play Episode Listen Later Aug 13, 2026 18:43


Recorded at HRS2026, this episode of The Lead features host Christopher Kowalewski, MD, in conversation with Junaid A.B. Zaman, MA, MD, PhD, CCDS, and Patrick Boyle, BS, PhD, FHRS, about the journal article, Digital Twin–Guided Ablation for Ventricular Tachycardia. Together, they discuss the study's findings and explore the use of digital twin technology to guide ventricular tachycardia ablation and its potential implications for clinical electrophysiology. Learning Objectives Review the design and key findings of the study evaluating digital twin–guided ablation for ventricular tachycardia. Discuss the use of digital twin technology as a tool to guide ventricular tachycardia ablation. Explore the potential clinical implications of digital twin–guided ablation for the management of ventricular tachycardia. Host: Christopher Kowalewski, MD   Guests: Junaid A.B. Zaman, MA, MD, PhD, CCDS  Patrick Boyle, BS, PhD, FHRS    Disclosures: C. Kowalewski No relevant disclosures   J Zaman Honoraria/Speaking/Consulting Fee: Acutus Medical Inc., Johnson and Johnson, American Medical Association, American College of Physicians, Bylis Medical Company Office/Trustee/Director/Other Fiduciary Role: Society of Bedside Medicine Travel/Entertainment: Boston Scientific   P Boyle Research: Seattle Foundation, Catherine Holmes Wilkins Charitable Foundation, NIH/NHLBI, American Heart Association Other Non-Financial Relationship: Cardiovascular Engineering and Technology Office/Trustee/Director/Other Fiduciary Role: The Cardiac Electrophysiology Society

WarDocs - The Military Medicine Podcast
Expeditionary Interventional Radiology: Make the Case for Endovascular Care Forward on the Battlefield- Dr. John Pavlus and Dr. Jonathan Schutt

WarDocs - The Military Medicine Podcast

Play Episode Listen Later Aug 12, 2026 51:09


    Bleeding is what kills people after trauma. That single fact sits at the center of this WarDocs episode, in which host Dr. Wayne Causey, a vascular surgeon, sits down with two military interventional radiologists — Dr. John Pavlus of Brooke Army Medical Center and Dr. Jonathan Schutt, an interventional radiology resident at Yale — to examine one of the fastest-moving areas in modern medicine and what it could mean for the wounded service member. Endovascular care, as they describe it, is deceptively simple to explain and remarkably hard to field: a small stick in the groin or the wrist, image guidance instead of an incision, and wires and catheters small enough to be called straws, threaded through the vascular tree to block a bleeding artery or reline an injured one. As one guest puts it, the patient goes home with a band-aid.    The conversation moves quickly from definition to system. At Brooke Army Medical Center, a trauma activation commits the interventional team to needle-stick access within sixty minutes of the call, day or night. That standard was not bought with equipment. It was built on years of bi-directional trust with the trauma surgeons, to the point that the team now responds without stopping to relitigate the imaging. Both guests are blunt that ownership is the price of admission: if interventional radiology wants a seat on the trauma team, it has to show up at two in the morning for cases that are neither lucrative nor glamorous.   The harder question is how far forward this capability can go. REBOA is scaled today at Role 2, and stent graft and embolization cases in Role 3 remain largely case-reportable events performed by clinicians who brought their own equipment. The limiting factor, both guests argue, is not technique — it is imaging, logistics, and institutional will. Meanwhile, Israeli teams transition to bunker operations within twenty-four hours, and Ukrainian experience with drone-driven injury patterns is already reshaping assumptions about REBOA and embolization that the United States has not yet tested.   The episode closes on people rather than platforms: the case for a military interventional community that crosses Service lines and partners with surgical colleagues, the argument for a skill identifier that lets the system find the right clinician, and a practical inventory of what one interventional radiologist would carry in a backpack if told to deploy tomorrow. Chapters (01:11-06:26) Two Pathways Into Military Interventional Radiology (06:26-10:15) Endovascular Care Explained: A Lot Through a Pinhole (10:15-17:02) The Sixty-Minute Trauma Activation at Brooke Army Medical Center (17:02-26:11) Forward Capability: REBOA, Stent Grafts, and the Role 2 and Role 3 Gap (26:11-35:54) Silos, Superpowers, and the Real Cost Equation (35:54-49:56) Allied Lessons, a Military IR Community, and What Fits in a Backpack Chapter Summaries (01:11-06:26) Two Pathways Into Military Interventional Radiology Both guests trace how they arrived at interventional radiology and at military service — one from the Air Force Academy and a fighter pilot track redirected by a day shadowing an orthopedic surgeon, the other from a childhood spent in a pararescue uncle's uniform and an HPSP commissioning. Each was pulled toward endovascular work by the same realization: that the future of the specialty was in doing more through less. Their training routes differ, one through diagnostic radiology and fellowship, the other through an integrated residency pathway. (06:26-10:15) Endovascular Care Explained: A Lot Through a Pinhole The guests define endovascular care in the language they use with patients: a small poke in the groin or the wrist, image guidance rather than an open field, and catheters threaded through the vascular tree like a plumber working pipes. Roughly ninety-five percent of the work is image guided, most often with fluoroscopy. The host adds the surgeon's framing — always ask what can be fixed through the blood vessel before opening a chest or an abdomen. (10:15-17:02) The Sixty-Minute Trauma Activation at Brooke Army Medical Center A blunt trauma patient arrives, CT shows active extravasation from a high-grade splenic injury, and the trauma activation commits the interventional team to needle-stick access within sixty minutes. The guests describe how that pathway was built on bi-directional trust rather than debate over each scan, and why the team now launches without relitigating the imaging. Both stress that owning trauma call — unglamorous, poorly reimbursed, and at all hours — is what earns interventional radiology its place on the team. (17:02-26:11) Forward Capability: REBOA, Stent Grafts, and the Role 2 and Role 3 Gap The conversation turns to what exists downrange. REBOA is scaled today at Role 2, and endovascular hemorrhage control at Role 3 remains largely a set of case reportable events performed with clinician-supplied equipment. The guests explain stent grafts as simultaneous hemorrhage control and reconstruction, and identify imaging, transport, and packaging — not procedural skill — as the true limiting factors on projecting this capability forward. (26:11-35:54) Silos, Superpowers, and the Real Cost Equation One guest argues that interventional radiology has been siloed by civilian incentives the military has no reason to copy, and that the specialty's real advantage is the fusion of diagnostic reading and procedural skill he calls a superpower. The host and guests weigh the higher up-front cost of advanced imaging and devices against the dramatically lower recovery burden of a pinhole procedure. The biggest hurdle, one guest says flatly, is people — convincing decision makers the capability is worth funding. (35:54-49:56) Allied Lessons, a Military IR Community, and What Fits in a Backpack Israeli teams shifting hospitals to bunker operations within twenty-four hours and Ukrainian experience with drone-driven injury patterns are held up as evidence the United States is playing catch-up. The guests describe the effort to build a military interventional radiology community across Services and to partner with the American College of Surgeons military chapter. The episode closes with a practical deployment loadout — ultrasound, micropuncture kits, sheaths, a base catheter, coils, and wire — and a walk through current training pathways into the specialty. Take Home Messages Bleeding is the mission. The immediate cause of preventable death after trauma is hemorrhage, which is why endovascular capability belongs in the operational conversation at all. Every argument for pushing this capability forward reduces to stopping the bleeding fast enough, and doing it without creating a second catastrophe. Framing the specialty this way makes its military relevance impossible to dismiss. Trust is the system, not the equipment. A sixty-minute call-to-stick standard at a level one trauma center was not purchased — it was built over years of bi-directional trust between the trauma team and the interventional service. Once that trust exists, the activation launches without relitigating the imaging, and everything else falls into motion. Any unit trying to replicate the capability should build the relationship before it buys the gear. Ownership earns the seat. Trauma call is unglamorous, poorly reimbursed, and inconvenient, which is exactly why some centers have written interventional radiology out of the pathway entirely. Showing up at two in the morning, reviewing imaging alongside the trauma team, and taking responsibility for the patient is what secures a permanent place on that team. Presence before the activation is what makes the activation work. The limiting factor is logistics, not technique. Everything done at a level one trauma center is technically achievable far forward — the constraint is diagnostic imaging, fluoroscopy, packaging, and airlift, not procedural skill. Progress therefore depends on investment decisions and institutional will rather than on new procedures. Convincing leaders that the capability is valuable is the hurdle, and funding follows conviction. Allies are already ahead, and the injury patterns are changing. Israeli teams move a hospital into bunker operations within twenty-four hours, and Ukrainian experience with drone-driven wounding is already reshaping assumptions about balloon occlusion and embolization. Planning for the last war is the fastest way to arrive unprepared for the next one. Learning from partner nations now is cheaper than relearning under fire. Episode Keywords military medicine, interventional radiology, endovascular care, WarDocs podcast, non compressible torso hemorrhage, REBOA, stent graft, embolization, hemorrhage control, combat casualty care, Brooke Army Medical Center, trauma activation, expeditionary interventional radiology, Role 2 care, Role 3 care, military trauma system, vascular surgery, image guided procedures, John Pavlus, Jonathan Schutt, Air Force medicine, Army medicine, military health system, battlefield medicine, damage control #WarDocs, #MilitaryMedicine, #InterventionalRadiology, #EndovascularCare, #CombatCasualtyCare, #HemorrhageControl, #TraumaCare, #MilitaryHealthSystem Honoring the Legacy and Preserving the History of Military Medicine The WarDocs Mission- WarDocs exists to honor the legacy of Military Medicine, preserve its history, and inspire every generation — across all Services, Corps, and Ranks — to serve with excellence and pride. Through mentorship, coaching, and education, we equip those considering, entering, and serving in military medicine with the knowledge, connections, and community they need to thrive. We celebrate Who we are, What we do, and, most importantly, How we serve Our Patients, the DoW, and Our Nation. Find out more and join Team WarDocs at https://www.wardocspodcast.com/ Check our list of previous guest episodes at https://www.wardocspodcast.com/our-guests Subscribe and Like our Videos on our YouTube Channel: https://www.youtube.com/@wardocspodcast Listen to the “What We Are For” Episode 47. https://bit.ly/3r87Afm WarDocs- The Military Medicine Podcast is a Non-Profit, Tax-exempt-501(c)(3) Veteran Run Organization run by volunteers. All donations are tax-deductible and go to honoring and preserving the history, experiences, successes, and lessons learned in Military Medicine. A tax receipt will be sent to you. WARDOCS documents the experiences, contributions, and innovations of all military medicine Services, ranks, and Corps who are affectionately called “Docs” as a sign of respect, trust, and confidence on and off the battlefield, demonstrating dedication to the medical care of fellow comrades in arms. Follow Us on Social Media Twitter: @wardocspodcast Facebook: WarDocs Podcast Instagram: @wardocspodcast LinkedIn: WarDocs-The Military Medicine Podcast YouTube Channel: https://www.youtube.com/@wardocspodcast

Resiliency Radio
329: Resiliency Radio with Dr. Jill: The Hidden Drivers of Brain Diseases with Dr. David Perlmutter

Resiliency Radio

Play Episode Listen Later Aug 12, 2026 49:17


  In this episode of Resiliency Radio with Dr. Jill, Dr. Jill Carnahan welcomes renowned neurologist and bestselling author Dr. David Perlmutter to explore the emerging science behind brain health, neuroinflammation, and cognitive resilience. Drawing from his groundbreaking new book, Brain Defenders, Dr. Perlmutter explains how microglia—the brain's immune cells—play a central role in protecting or damaging the brain depending on our metabolism, lifestyle, and environment. Together they discuss why Alzheimer's and Parkinson's disease begin decades before symptoms appear, why inflammation and insulin resistance are major drivers of neurodegeneration, and what we can do today to protect lifelong brain health. Whether you're concerned about memory loss, dementia prevention, or optimizing cognitive performance, this episode offers science-backed strategies to build a healthier, more resilient brain.

Triple Play Performance Podcast
EP 129: How not be a statistic for the top 10 leading causes of death

Triple Play Performance Podcast

Play Episode Listen Later Aug 12, 2026 26:51


Disclaimer: This episode and article are for educational purposes only and are not a substitute for individualized medical advice. Always consult your physician before making changes to your diet, exercise routine, or medications.TL;DR* The CDC's top 10 causes of death account for roughly 74% of all deaths in the US each year, and up to 80% of chronic disease is estimated to be driven by lifestyle factors — diet, movement, sleep, stress, and toxin exposure. * This episode goes cause by cause (heart disease, cancer, COVID/respiratory disease, accidents, stroke, Alzheimer's, diabetes, kidney disease, flu/pneumonia, and suicide) and lays out what the peer-reviewed research says about preventing, slowing, or reversing each one.* Ready to build your own plan? Book a free Metabolic Blueprint Session →The List, and the Number That Should Keep You Up at NightAccording to the CDC, ten conditions account for about 74% of all deaths in the United States every year:* Heart disease* Cancer* COVID-19 / chronic lower respiratory diseases* Accidents (unintentional injuries)* Stroke* Alzheimer's disease* Diabetes* Kidney disease* Influenza and pneumonia* SuicideHere's the part that doesn't get said enough: research estimates that up to 80% of chronic disease is driven by lifestyle factors — diet, movement, sleep, stress, and toxin exposure. Those aren't destinies. They're decisions, and decisions can change.A landmark paper in the Journal of the American Medical Association found that poor diet alone accounts for more deaths in the US than tobacco use. The fork may be more dangerous than the cigarette. And yet, most patients who end up on four to six medications were never once asked what they eat, how they sleep, or whether they move their bodies before those prescriptions were written. That's the difference between a sick care system and a healthcare system.Heart Disease and Stroke: The Most Reversible Disease We KnowHeart disease kills one American every 34 seconds and has held the #1 spot for over a century. But it's also one of the most reversible conditions in medicine.In 1990, Dr. Dean Ornish's landmark Lifestyle Heart Trial showed that intensive lifestyle changes — diet, exercise, stress management, and social support — could reverse coronary artery disease without drugs or surgery. Arterial plaques reduced. Blood flow improved. Chest pain decreased. A 2019 study in the Journal of the American College of Cardiology confirmed it: a plant-predominant diet, regular aerobic exercise, not smoking, and a healthy weight reduced cardiovascular risk by over 80%.What that looks like in practice:* A Mediterranean or whole-food, plant-based diet rich in omega-3s and antioxidants (this isn't the only diet that works — it's the broadest evidence-backed baseline)* Zone 2 cardio (low-intensity aerobic work, three to five times a week — a brisk walk counts)* Managing chronic inflammation, the real driver of arterial plaque formation* Reducing refined sugar and seed oils, which damage the endothelial lining of the arteries* Prioritizing sleep, since poor sleep spikes cortisol and directly harms the heartStroke follows the same playbook: control blood pressure through diet, exercise, and stress reduction. The DASH diet in particular has been shown in multiple studies to lower blood pressure as effectively as medication in many patients.Cancer: 30–50% Preventable, and Possibly More Metabolic Than GeneticTo be clear, this isn't a claim about curing cancer — it's about how much prevention research is available and underused. The World Health Organization estimates that 30–50% of cancers are preventable. The American Institute for Cancer Research has identified lifestyle factors that dramatically reduce risk across multiple cancer types:* Diet. A 2022 meta-analysis in The Lancet linked poor dietary patterns — low fiber, low fruit/vegetable intake, high processed meat — to one in five cancer deaths globally.* Obesity. Excess weight is now the second-leading risk factor for cancer after smoking, because fat tissue is metabolically active and produces hormones like estrogen and inflammatory cytokines that fuel cancer growth.* Exercise. A 2019 study of over 1.4 million people found higher physical activity was associated with lower risk across 13 cancer types, including breast, colon, and endometrial cancer.* Fasting and metabolic health. Emerging research on intermittent fasting and time-restricted eating shows it can lower insulin-like growth factor, a key promoter of cancer cell proliferation.* Toxin reduction. Chronic low-grade exposure to pesticides, plastics (BPA, phthalates), and environmental pollutants has been linked to increased cancer risk. Choosing organic where possible, filtering water and air, and reducing plastic in cookware and storage all matter.There's also a deeper shift happening in how researchers understand cancer itself. It's long been treated primarily as a genetic disease, but the evidence is increasingly pointing toward cancer as a metabolic disease. Dr. Thomas Seyfried at Boston College has done groundbreaking work showing that cancer cells overwhelmingly rely on glucose and glutamine fermentation for energy — which is why a ketogenic or low-glycemic approach may help starve cancer cells while protecting healthy ones. The research is still evolving, but it's compelling.Think of your body like a garden. You can water it, enrich the soil, and pull the weeds — or you can dump sugar and chemicals on it and wonder why nothing grows right. Disease doesn't happen to you. It grows in an environment you create, consciously or not. The good news: you can change that environment starting today.Alzheimer's: “Type 3 Diabetes”Alzheimer's is rising, and it's terrifying to watch someone go through it. But emerging science shows it has a strong lifestyle and metabolic component — researchers now sometimes call it “type 3 diabetes” because of the profound link between insulin resistance and neurodegeneration.Dr. Dale Bredesen's ReCODE Protocol, published in the Journal of Aging, showed that a multimodal lifestyle intervention — diet, exercise, sleep optimization, hormone balancing, and stress reduction — reversed early cognitive decline in the majority of patients treated. In his 2014 case series, 9 of 10 patients with early Alzheimer's or mild cognitive impairment showed measurable improvement, with several returning to work.Key strategies from the research:* Sleep is non-negotiable. The brain's glymphatic (waste clearance) system activates primarily during sleep, flushing out amyloid beta plaque. Poor sleep means plaque buildup.* Exercise. A 2020 study showed aerobic exercise increases BDNF (brain-derived neurotrophic factor) — essentially fertilizer for neurons — and reduces dementia risk by up to 35%.* Mediterranean-MIND diet. Shown to slow cognitive aging by an estimated 7.5 years in adherent individuals.* Blood sugar management. Insulin resistance in the brain disrupts its ability to use glucose for energy, effectively starving neurons.* Social connection. Harvard's 80-year longitudinal study found relationship quality was the single strongest predictor of cognitive health and longevity in old age.Type 2 Diabetes and Kidney Disease: One Disease Driving AnotherOver 37 million Americans have type 2 diabetes, and another 96 million are pre-diabetic. Here's the part that surprises people: type 2 diabetes is reversible in the majority of cases, and this isn't controversial — the science is overwhelming.The 2019 DiRECT trial, published in The Lancet, found that nearly half of type 2 diabetics achieved full remission through an intensive dietary intervention alone, with no medication. Other studies using low-carbohydrate and very-low-calorie diets have replicated these results consistently.Diabetic nephropathy — kidney damage from chronically high blood sugar — is the leading cause of kidney failure in the US. Control the upstream issue (blood sugar and metabolic dysfunction) and you protect the downstream organ.The diabetes reversal framework from the research:* Dramatically reduce refined carbohydrates and added sugars to blunt insulin spikes and reduce fat storage in the liver and pancreas* Practice time-restricted eating or intermittent fasting to improve insulin sensitivity* Add resistance training — muscle is your biggest glucose sink, so more muscle means better blood sugar control* Reduce visceral fat (the fat around and inside your organs), a key driver of insulin resistance and inflammationIf this list feels like a lot, that's fair. But it's not about blame — it's about empowerment. You have more control over your health outcomes than the medical system has typically told you.Respiratory Disease, Flu, and PneumoniaChronic lower respiratory diseases like COPD and emphysema are largely driven by smoking and air quality. Quitting smoking remains the single most impactful intervention here, full stop.For flu and pneumonia risk, immune resilience matters: vitamin D optimization, zinc and elderberry, and gut microbiome health (roughly 70% of your immune system lives in your gut). Even mild sleep deprivation has been shown to quadruple susceptibility to viral infection.Suicide and Mental HealthThis is the cause of death nobody wants to talk about, but it's in the top 10 — and it's the leading cause of death for men under 50, and the second-leading cause of death for people ages 10–34.While this is complex and deeply personal, research points to several lifestyle levers:* Exercise functions as an effective antidepressant, largely through endorphin release* The gut-brain axis matters more than most people realize — over 75% of the body's serotonin is produced in the gut, so gut health directly shapes brain chemistry* Social connection and purpose. Viktor Frankl's Man's Search for Meaning, written while he was in a Nazi concentration camp, captured this: meaning and connection to purpose are essential for survival, and perspective shapes both physiology and outcome* Reducing alcohol, a central nervous system depressant that worsens anxiety and depression despite short-term reliefIf you or someone you love is struggling, crisis hotlines are available 24/7. There's often a reason it's happening, and there's often a way through it.The Common ThreadAcross every single one of these conditions — heart disease, stroke, cancer, Alzheimer's, diabetes, kidney disease, respiratory disease, immune function, mental health — the same five levers keep showing up: diet, exercise, sleep, toxin reduction, and blood sugar balance.Your daily habits are either building disease or building resilience. Every meal, every walk, every night of good sleep compounds — just like interest in a bank account.This Week's Action Plan* Do a food audit. For the next three days, write down everything you eat. No judgment, just awareness — you can't change what you can't see.* Walk 30 minutes a day. It lowers blood pressure, improves insulin sensitivity, boosts BDNF, and reduces cortisol. Simple, not easy — do it anyway.* Optimize your sleep. Consistent bedtime, dark room, cool temperature, no screens.* Get your labs done. Know your fasting glucose, A1C, CRP, vitamin D, triglycerides, and LDL — these are your early warning systems.* Address one stress source this week. A conversation you need to have, a boundary you need to set, or ten minutes of breathwork. Chronic stress is silently killing you — take action on it.Ready for a Real Plan?If you're ready to take your health seriously and want a clear roadmap instead of guesswork, book a Metabolic Blueprint Session. In 30–45 minutes, we'll walk through your top three priority areas and how programs like the Metabolic Momentum Accelerator, the Cellular Reboot Accelerator, and the Total Health Restore Protocols can help.Schedule your complimentary consult →Know someone this could help? Share this episode with them — it might change or even save their life.If this episode was valuable, leaving a review on Spotify or Apple Podcasts helps this show reach more people.ReferencesStudies and sources cited in this episode:* CDC — Leading Causes of Death data* Journal of the American Medical Association (JAMA) — poor diet and US mortality* Ornish, D. et al. (1990) — The Lifestyle Heart Trial* Journal of the American College of Cardiology (2019) — plant-predominant diet, exercise, and cardiovascular risk reduction* DASH diet research on blood pressure control* World Health Organization (WHO) — cancer preventability estimates* American Institute for Cancer Research — lifestyle and cancer risk* The Lancet (2022 meta-analysis) — dietary patterns and cancer deaths* Physical activity and cancer risk study (2019, ~1.4 million participants)* Seyfried, T., Boston College — cancer as a metabolic disease* Bredesen, D., Journal of Aging — the ReCODE Protocol; 2014 case series* BDNF and exercise study (2020) — dementia risk reduction* Mediterranean-MIND diet and cognitive aging research* Harvard Study of Adult Development (80-year longitudinal study) — relationships and longevity* DiRECT Trial, The Lancet (2019) — type 2 diabetes remission through dietary intervention* Frankl, V. — Man's Search for MeaningThis article summarizes claims and studies as presented in the podcast episode. Listeners are encouraged to review primary sources directly and consult their own physician before making health decisions. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit tripleplaydoc.substack.com/subscribe

Live Foreverish
358. Summary: Want to End Chronic Inflammation? This Helps! - Life Extension

Live Foreverish

Play Episode Listen Later Aug 12, 2026 3:22


The Future of Inflammation Resolution In this episode of Live Foreverish, Dr. Mike and Dr. Crystal welcome Harvard researcher Dr. Charles Serhan to discuss resolution medicine, a groundbreaking field focused on activating the body's natural inflammation-resolving mechanisms. Dr. Serhan explains how specialized pro-resolving mediators (SPMs), derived from omega-3 fatty acids like EPA and DHA, actively resolve inflammation rather than simply suppressing it. This show offers promising new strategies for treating chronic inflammatory diseases. #LELEARN #EDULFsocial Guest Bio: Prof. Charles Nicholas Serhan, PhD, DSc is the Simon Gelman Professor of Anaesthesia (Biochemistry and Molecular Pharmacology) at Harvard Medical School and Professor of Oral Medicine, Infection and Immunity at Harvard School of Dental Medicine. He is Director of the Center for Experimental Therapeutics and Reperfusion Injury at Brigham and Women's Hospital. He has received several awards including an NIH MERIT award (2000) and has delivered over 50 keynote and plenary lectures. Among these, 2008 William Harvey Outstanding Scientist Medal and AAAS Fellow in 2011. In 2010, he received the Society for Leukocyte Biology Bonazinga Award for outstanding research on leukocytes, The American College of Rheumatology Hench (Nobel Laureate) Award Lecture in 2011 and is a Mérieux 2013 Laureate. In 2016, he received the IUBMB Lecture Medal and the Ross Prize in Molecular Medicine. In 2017, he received the International Eicosanoid Research Foundation's Lifetime Achievement Award and the American Society of Investigative Pathology (ASIP) 2018 Rous Whipple Award.

ACR on Air
The 2026 Adult/Juvenile Spondyloarthritis Guidelines

ACR on Air

Play Episode Listen Later Aug 11, 2026 44:47


The new clinical guidelines for juvenile and adult axial spondyloarthritis (axSpA), developed collaboratively by the American College of Rheumatology (ACR), the Spondylitis Association of America (SAA), and the Spondyloarthritis Research and Treatment Network (SPARTAN), mark an important evolution in the management of this complex disease. In this episode, Drs. Liron Caplan and Matthew Stoll discuss what's changed, why it matters, and how these recommendations can guide everyday clinical practice—from the first-ever juvenile axSpA guideline and the unified approach to radiographic and non-radiographic disease, to practical decisions around MRI use, first-line therapies, biologic selection, treatment failure, and physical activity.  2026 Update of the American College of Rheumatology/Spondylitis Association of America/Spondyloarthritis Research and Treatment Network Recommendations for the Treatment of Axial Spondyloarthritis in Adults and Children/Adolescents  

Dean's Chat - All Things Podiatric Medicine
Ep. 350 - Michael Cornelison: Moving Forward Together: Leadership and Collaboration in Podiatry

Dean's Chat - All Things Podiatric Medicine

Play Episode Listen Later Aug 11, 2026 56:01


In this episode of Dean's Chat, Drs. Jeffrey Jensen and Johanna Richey welcome Dr. Michael Cornelison, former president of the American College of Foot and Ankle Surgeons (ACFAS) and current executive director of the California Podiatric Medical Association (CPMA), for a wide-ranging conversation about leadership, mentorship, collaboration, and the future of podiatric medicine. Dr. Cornelison also offers a unique perspective as a father of three daughters, two of whom have followed him into podiatric medicine. He reflects on the importance of leading by example and allowing the next generation to discover their own reasons for choosing the profession. His daughters' journeys have reinforced his belief that podiatry needs to introduce students to the profession much earlier and demonstrate not only the clinical opportunities, but also the fulfillment, flexibility, and diverse career paths available to DPMs.Dr. Cornelison shares his own circuitous path into podiatry, beginning with an interest in biomechanics and musculoskeletal physiology at UCLA. A chance recommendation from a pre-health counselor, followed by an unexpected connection with podiatrist and mentor Dr. Jeff Stone, ultimately led him to Scholl College and then to residency training at Inova. He describes how mentors, senior residents, and the culture of his training program helped foster his interest in leadership and reinforced the idea that podiatrists have an important role to play beyond the clinic and operating room.The discussion explores Dr. Cornelison's leadership journey through ACFAS, including his experience navigating the organization through the challenges of the COVID-19 pandemic and ultimately serving as president. A central theme of his leadership philosophy is collaboration. He discusses his efforts to bring organizations including ACFAS, APMA, AAOS, and AOFAS together around shared priorities such as reimbursement, advocacy, and the advancement of podiatric medicine. He emphasizes that progress does not require having every answer in advance; sometimes leaders must be willing to remain open-minded, listen to different perspectives, and build consensus.Dr. Cornelison also discusses leadership development and the importance of creating pathways for individuals from all backgrounds and training programs to become involved. He highlights emerging leadership initiatives within ACFAS and APMA as opportunities to cultivate the next generation of leaders. His advice is particularly relevant to anyone seeking greater professional fulfillment: find a niche beyond the traditional nine-to-five clinical role, whether through leadership, advocacy, research, education, or another area of interest. By staying engaged, embracing collaboration, and focusing on what can be controlled, podiatrists can help move the profession forward while finding greater purpose and satisfaction in their own careers.

College and Career Clarity
Who Should Be on Your Teen's College Planning Team? with Stephanie Simpson

College and Career Clarity

Play Episode Listen Later Aug 11, 2026 26:02


Parents often assume their teen's school counselor can handle every part of the college planning process, but the reality is far more collaborative.In this episode, Lisa Marker-Robbins and Stephanie Simpson, CEO of the Independent Educational Consultants Association (IECA), explore how the right team and a foundation of self-awareness can help students make thoughtful college decisions.In this episode, Lisa and Stephanie discuss:How school counselors, independent educational consultants, and families each contribute to college planningWhy self-awareness should guide college and career decisions from the startWhen outside college planning support can benefit students and familiesWhat to consider when choosing an independent educational consultantKey Takeaways: Start career and identity exploration before college applications so students make decisions based on who they are, not deadlines.Independent educational consultants help students present their authentic story and find the right college fit, not improve their admissions odds.Many begin in junior year; starting by sophomore year creates more time for thoughtful course selection, extracurriculars, and summer opportunities.Choose an independent educational consultant whose expertise matches your student's needs and complements the school counselor's support. “Independent means that these counselors do not receive any compensation from a program, school, or university to place or recommend a student, so they really can provide that unbiased advice.” – Stephanie SimpsonAbout Stephanie Simpson: Stephanie Simpson is the Chief Executive Officer of IECA, the leading professional organization for independent educational consultants supporting students and families through college and career planning. Previously, she led the Association for Middle Level Education (AMLE) and held senior leadership roles at the American College of Cardiology and the American Psychiatric Association. She holds a JD from Northwestern University Pritzker School of Law and a BA from DePaul University.Episode References:Learn more about Launch Career Clarity at https://flourishcoachingco.com/courseFind a Private College Counselor: https://www.iecaonline.com/independent-educational-consultant-search/#230 Stop Trying to Impress Colleges: What Admissions Really Want with Susan Knoppow: https://flourishcoachingco.com/230Get Lisa's Free on-demand video: THE CAREER IDENTIFICATION COMPASS: How To Be Certain Your 15 To 25 Year Old is On The Right Path to Launch With Confidence–Not Confusion: flourishcoachingco.com/video Connect with Stephanie:Website: https://www.iecaonline.com/LinkedIn: https://www.linkedin.com/in/stephanie-simpson-49bba72a/Connect with Lisa:Website: https://www.flourishcoachingco.com/YouTube: https://www.youtube.com/@flourishcoachingcoFacebook: https://www.facebook.com/flourishcoachingco/ Instagram: https://www.instagram.com/flourishcoachingco/LinkedIn: https://www.linkedin.com/company/flourish-coaching-co

Just Grow Something | A Gardening Podcast
Organic, Conventional, or Homegrown: What the Research Really Shows About Nutrition - Ep. 313

Just Grow Something | A Gardening Podcast

Play Episode Listen Later Aug 11, 2026 31:18


You've probably heard both sides of this argument: that organic and conventional produce are nutritionally identical, and that homegrown vegetables blow store-bought out of the water. Which one is true? In this episode, I dig through the peer-reviewed research on three separate questions: whether organic farming produces more nutritious food, whether soil health itself changes the nutrient content of what we eat, and what happens to those nutrients in the days between harvest and the moment food lands on your plate. I'm treating this as a real meta-analysis, pulling together findings from major systematic reviews, long-term field trials, and postharvest storage studies, and following the data wherever it leads. The answer is more interesting, and more useful for your own garden, than either side of the argument usually admits. By the end, you'll know exactly which parts of the nutrient-density conversation hold up under scrutiny and which parts are oversimplified, plus what it means for the food coming out of your own backyard. Let's dig in! Get your bag of Larry's Coffee and a free gift from their fair-trade partners at https://LarrysCoffee.com/JustGrow Peer-Reviewed Sources Smith-Spangler et al. (2012), Annals of Internal Medicine — Are Organic Foods Safer or Healthier Than Conventional Alternatives?: https://www.acpjournals.org/doi/10.7326/0003-4819-157-5-201209040-00007 Baranski et al. (2014), British Journal of Nutrition — Higher Antioxidant and Lower Cadmium Concentrations in Organically Grown Crops (343-study meta-analysis): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141693/ Worthington (2001), Journal of Alternative and Complementary Medicine — Nutritional Quality of Organic Versus Conventional Fruits, Vegetables, and Grains: https://pubmed.ncbi.nlm.nih.gov/11327522/ Hunter et al. (2011), Critical Reviews in Food Science and Nutrition — Evaluation of the Micronutrient Composition of Plant Foods Produced by Organic and Conventional Methods: https://pubmed.ncbi.nlm.nih.gov/21929333/ Montgomery & Biklé (2021), Frontiers in Sustainable Food Systems — Soil Health and Nutrient Density: Beyond Organic vs. Conventional Farming: https://www.frontiersin.org/journals/sustainable-food-systems/articles/10.3389/fsufs.2021.699147/full Lehmann et al. (2014), Soil Biology and Biochemistry — Arbuscular Mycorrhizal Influence on Zinc Nutrition in Crop Plants: A Meta-Analysis: https://www.sciencedirect.com/science/article/abs/pii/S0038071713004045 Reganold et al. (2010), PLOS ONE — Fruit and Soil Quality of Organic and Conventional Strawberry Agroecosystems: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0012346 Helfenstein et al. (2016), PLOS ONE — Organic Wheat Farming Improves Grain Zinc Concentration: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0160729 Hepperly, Omondi & Seidel (2018), MOJ Food Processing & Technology — Soil Regeneration Increases Crop Nutrients, Antioxidants and Adaptive Responses (Rodale Institute Farming Systems Trial): https://medcraveonline.com/MOJFPT/soil-regeneration-increases-crop-nutrients-antioxidants-and-adaptive-responses.html Davis, Epp & Riordan (2004), Journal of the American College of Nutrition — Changes in USDA Food Composition Data for 43 Garden Crops, 1950 to 1999: https://pubmed.ncbi.nlm.nih.gov/15637215/ Marles (2017), Journal of Food Composition and Analysis — Mineral Nutrient Composition of Vegetables, Fruits and Grains: The Context of Reports of Apparent Historical Declines: https://www.sciencedirect.com/science/article/pii/S0889157516302113 Favell (1998), Food Chemistry — A Comparison of the Vitamin C Content of Fresh and Frozen Vegetables: https://www.sciencedirect.com/science/article/abs/pii/S0308814697001659 Rickman, Barrett & Bruhn (2007), Journal of the Science of Food and Agriculture — Nutritional Comparison of Fresh, Frozen and Canned Fruits and Vegetables, Part 1: https://scijournals.onlinelibrary.wiley.com/doi/abs/10.1002/jsfa.2825 Li, Pegg, Eitenmiller, Chun & Kerrihard (2017), Journal of Food Composition and Analysis — Selected Nutrient Analyses of Fresh, Fresh-Stored, and Frozen Fruits and Vegetables: https://www.sciencedirect.com/science/article/abs/pii/S0889157517300418 Galani et al. (2017), Antioxidants — Storage of Fruits and Vegetables in Refrigerator Increases Their Phenolic Acids but Decreases the Total Phenolics, Anthocyanins and Vitamin C: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618087/ Jo, Shin & Lee (2003), Journal of Agricultural and Food Chemistry — The Effect of Post-Harvest and Packaging Treatments on Glucoraphanin Concentration in Broccoli: https://pubs.acs.org/doi/10.1021/jf0203592 Just Grow Something: https://justgrowsomething.com Gardening Courses: https://justgrowsomething.com/courses Just Grow Something Merch and Downloads: https://justgrowsomething.com/shop Just Grow Something Gardening Friends Facebook Group: https://www.facebook.com/share/g/18YgHveF5P/ Check out how you can become a patron on Patreon: https://www.patreon.com/JustGrowSomething Feed my coffee habit: https://buymeacoffee.com/justgrowsomething Amazon storefront: https://www.amazon.com/shop/justgrowsomething Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

ACTEC Trust & Estate Talk
Trust Modification: When Flexibility Conflicts With Settlor Intent

ACTEC Trust & Estate Talk

Play Episode Listen Later Aug 11, 2026 13:54


Learn when an irrevocable trust can be modified, how courts define material purpose, and the legal risks of judicial and non-judicial trust changes. The American College of Trust and Estate Counsel, ACTEC, is a professional society of peer-elected trust and estate lawyers in the United States and around the globe. This series offers professionals best practice advice, insights, and commentary on subjects that affect the profession and clients. Learn more in this podcast.

The Dr. Axe Show
The 25-Year Rash: Dr. Steven Zodkoy on Biofilms, Buried Trauma, and Why Your UTI Isn't a UTI

The Dr. Axe Show

Play Episode Listen Later Aug 10, 2026 62:00


A rash baffled 25 years of dermatologists. It disappeared in a week once Dr. Steven Zodkoy traced it to a childhood memory. Here's what that case, and the concept of a "biofilm," has to do with your migraines and your bladder. Dr. Chris Motley sits down with Dr. Steven Zodkoy, a chiropractor and applied kinesiologist who became the first in his field to pass the American College of Nutrition exam, a credential previously reserved for MDs and PhDs. Thirty-five years into practice, Dr. Zodkoy specializes in the patient conventional medicine gave up on: the migraine sufferer, the "recurring UTI" patient who never actually had a UTI, the chronic fatigue case with a normal bloodwork panel. His framework rests on one idea most doctors do not test for: the biofilm, a sticky protective layer that bacteria, viruses, mold, and parasites lay down to hide from the immune system and from treatment. Once one pathogen builds a biofilm, Zodkoy argues, it invites others in, which is why a "cured" infection so often resurfaces as something else entirely, chronic sinusitis becoming Lyme-like fatigue, a bladder infection becoming a lifetime of unexplained pelvic tightness, a resistant childhood strain becoming an adult autoimmune diagnosis.  Key Takeaways Biofilms are why a "cleared" infection keeps coming back as something else. A biofilm is the mucous-like shield a bacterium, virus, parasite, or mold colony builds to hide from the immune system and from antibiotics. Once it's there, he says, it invites other pathogens to shelter in it too, which can explain why chronic sinusitis, Lyme-linked fatigue, and mold exposure so often show up in the same patient.  Interstitial cystitis is frequently a tight-bladder problem being treated as a recurrent UTI. Dr. Zodkoy's read: stress and anxiety tighten the bladder, it never fully empties, and what's left behind gets infected, so the antibiotic treats a symptom while the muscle stays tight and the infections keep returning. His protocol adjusts the pelvic floor and pubic symphysis, then layers in biofilm-breaking supplements and emotional work.  A 25-year rash resolved after one round of Neuro-Emotional Technique tied to an age-seven memory. Every physical test on this patient, mold, yeast, parasites, heavy metals, came back clean. Emotional testing didn't.  His migraine protocol runs liver support first, nervous system second, emotional work third, in that order, on purpose. Dr. Zodkoy's 1992 theory ties migraines to a slow-functioning liver overloaded by chemical exposure, hormones, or diet. He walks us through his 8-week liver protocol, 16 weeks including autonomic nervous system support, and a 96% success rate once emotional work is added. You cannot do deep detox or trauma work on a nervous system that has nothing left. There's no point moving to detox, biofilm-clearing, or emotional release until a patient's self-rated energy crosses roughly 50 to 60 out of 100.  [00:00:00] Cold open: migraines, interstitial cystitis, chronic fatigue, and the biofilm nobody explains  [00:02:02] Origin story: "doctor, lawyer, doctor" and practicing three months before 25  [00:04:04] Why he became a nutritionist first: the autonomic nervous system as the missing piece  [00:06:08] Finding a hidden emotion: the six-minute visit versus a real history  [00:09:37] The HPA axis toolkit: DHEA, GABA, adaptogens, and a gut bacterium built for stress  [00:11:27] NET, emotion code, and generational trauma: "it doesn't have to be real, it has to be believed"  [00:14:36] The 25-year rash: a muscle test, a forgotten age seven, and a mother's confession  [00:19:04] Migraines: the 1992 liver theory, the 80/20 split, and a claimed 96% success rate  [00:23:43] Interstitial cystitis is not a UTI: the tight bladder nobody is treating [00:27:06]  Killing the biofilm: natokinase, antimicrobials, and cranial electrotherapy stimulation  [00:31:29] The sympathetic-parasympathetic seesaw, and why healing collapses without it  [00:34:59] The "oomph" scale: testing cortisol at home and in the office  [00:36:27] The protocol in order: glandulars, adaptogens, and parasympathetic support, dosed on purpose  [00:43:30] Chronic fatigue, sinus biofilms, and the "house party" that becomes Lyme, EBV, and mold  [00:47:19] Parasites in America, and the TG/HDL ratio he says predicts heart risk  [01:00:02] Closing: where to find Dr. Zodkoy, and a teed-up follow-up on the healthcare system Resources Mentioned Tools & Products Biofilm Clear: Zodkoy's stated favorite combination product for breaking down biofilms, made up of natokinase, serrapeptase, lumbrokinase, and bromelain. He describes dosing at 2000 IU for patients under 50 and up to 4000 IU for patients over 50 with abnormal bloodwork. CP2305 (referenced in audio as "PC2305"): a Lactobacillus gasseri probiotic strain studied for stress and HPA-axis effects. True Laser: a home low-level laser device Zodkoy places over the vagus nerve. Cranial electrotherapy stimulation (CES) units: clip-on-the-ear devices Zodkoy uses for anxiety, sleep, depression, and (with pads placed over the bladder) interstitial cystitis relief. Adrenal glandular products (brand examples given: Adrenal Complex from Designs for Health, Adrenal from Orthomolecular, Cortex from Thorne Research), used at a fraction of label dose, one pill in the morning only, per Zodkoy's protocol. Adaptogens referenced: ashwagandha, holy basil, rhodiola, cordyceps. • Nervous-system support referenced: DHEA, L-theanine, GABA, phosphatidylserine, adrenoglandulars. Antimicrobials referenced for biofilm-associated infections: berberine, olive leaf, oregano. Nutrients referenced for liver-support migraine protocol: B vitamins, glutathione, NAC. Concepts referenced: HPA axis (hypothalamus-pituitary-adrenal): the stress-response pathway Zodkoy targets before any other intervention. Applied kinesiology: manual muscle testing Zodkoy uses to distinguish emotional, physical, biochemical, parasitic, fungal, or toxic causes of a symptom. NET (Neuro-Emotional Technique), Emotion Code, Body Code: hands-on techniques used to locate and release stored emotional triggers. Sympathetic and parasympathetic nervous system balance: the "seesaw" framework underlying his treatment sequencing. • Triglyceride-to-HDL ratio: Zodkoy's preferred cardiovascular risk marker over total cholestero Want more of The Ancient Health Podcast? Subscribe to the YouTube channel. ------  Follow Doctor Motley! Instagram TikTok Facebook Website Follow Dr. Steven Zodkoy https://www.instagram.com/drstevenzodkoy/ ------  *You can get cell support in gummy form: Mitopure now starts at $79, when you go to timeline.com/DRMOTLEY. *Join Doctor Motley's newsletter for TCM insights and regular podcast updates https://www.doctormotley.com/ *Do you have a ton more in-depth questions for Doctor Motley? Check out his course on emotions and the body in his membership. You'll find other courses full of his expertise and clinical wisdom, plus bring all your questions to his weekly lives! To try risk-free for 15 days click here https://www.doctormotley.com/15

Portable Practical Pediatrics
Dr. M's Women and Children First Podcast #116: Russell Greenfield, MD – The Art of Listening

Portable Practical Pediatrics

Play Episode Listen Later Aug 10, 2026 70:18


Welcome back to Dr. M's Women and Children First. One of the recurring themes on this podcast is that the future of medicine won't be discovered through faster-paced healthcare alone. It will be discovered by slowing down, listening more carefully, and embracing a patient-centered approach that seeks to understand the whole person—not just the disease. Ultimately, the future of medicine begins with a better question: How do we truly hear a patient's story so that we can better serve the person sitting in front of us? Today's guest has spent his entire career helping answer that question. Our conversation today centers on one of the most overlooked aspects of healing: why so many people struggle to begin the healing process in the first place—and more importantly, how we, as clinicians, parents, and patients, can help that process finally move forward. Dr. Russell Greenfield is a board-certified emergency medicine physician and a Diplomate of the American College of Lifestyle Medicine whose career has been dedicated to transforming healthcare from a disease-centered model into one focused on whole-person health. He has served as Medical Director of Integrative Medicine for major health systems, including Novant Health and the Weisiger Cancer Institute, held national leadership positions within the Veterans Health Administration's Whole Health Initiative, and continues to advise organizations across the country that are reimagining what healthcare can become. What makes Dr. Greenfield's journey especially unique is that he was one of the select physicians chosen to complete a residential fellowship under the mentorship of Dr. Andrew Weil at the University of Arizona—the birthplace of academic integrative medicine. At a time when very few physicians were willing to challenge the traditional boundaries of healthcare, Dr. Greenfield immersed himself in a model that recognized nutrition, movement, sleep, stress, relationships, purpose, and environment as fundamental pillars of health, while embracing the remarkable advances of modern medical science. For me, this conversation is especially meaningful because many of us in medicine are asking the same question: How do we move upstream? How do we stop waiting for chronic disease to develop and instead create the conditions where health can flourish? Today we'll explore the art of becoming an experienced listener in service of the patient before us. We'll discuss why curiosity often matters more than certainty, why healing frequently begins long before the prescription pad comes out, and how understanding a person's story can unlock opportunities that laboratory tests and imaging studies alone may never reveal. Whether you're a clinician, a parent, or simply someone searching for a deeper understanding of health, I think you'll come away from this conversation with a renewed appreciation for one of medicine's most powerful tools: listening. Enjoy, Dr. M

The Joyce Kaufman Show
Joyce's Thought of the Day 8/10/26 - Universities neglecting to protect Jewish students from pro-Palestinian protesters following October 7th

The Joyce Kaufman Show

Play Episode Listen Later Aug 10, 2026 3:01


Joyce talks about have many American universities often rally to defend marginalized students but failed to rally behind Jewish student who faced discrimination or who felt unprotected during pro- Palestinian protesters following the October 7th massacre and the war in Gaza. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Live Foreverish
358. Want to End Chronic Inflammation? This Helps! - Life Extension

Live Foreverish

Play Episode Listen Later Aug 10, 2026 36:23


The Future of Inflammation Resolution In this episode of Live Foreverish, Dr. Mike and Dr. Crystal welcome Harvard researcher Dr. Charles Serhan to discuss resolution medicine, a groundbreaking field focused on activating the body's natural inflammation-resolving mechanisms. Dr. Serhan explains how specialized pro-resolving mediators (SPMs), derived from omega-3 fatty acids like EPA and DHA, actively resolve inflammation rather than simply suppressing it. This show offers promising new strategies for treating chronic inflammatory diseases. #LELEARN #EDULFsocial Guest Bio: Prof. Charles Nicholas Serhan, PhD, DSc is the Simon Gelman Professor of Anaesthesia (Biochemistry and Molecular Pharmacology) at Harvard Medical School and Professor of Oral Medicine, Infection and Immunity at Harvard School of Dental Medicine. He is Director of the Center for Experimental Therapeutics and Reperfusion Injury at Brigham and Women's Hospital. He has received several awards including an NIH MERIT award (2000) and has delivered over 50 keynote and plenary lectures. Among these, 2008 William Harvey Outstanding Scientist Medal and AAAS Fellow in 2011. In 2010, he received the Society for Leukocyte Biology Bonazinga Award for outstanding research on leukocytes, The American College of Rheumatology Hench (Nobel Laureate) Award Lecture in 2011 and is a Mérieux 2013 Laureate. In 2016, he received the IUBMB Lecture Medal and the Ross Prize in Molecular Medicine. In 2017, he received the International Eicosanoid Research Foundation's Lifetime Achievement Award and the American Society of Investigative Pathology (ASIP) 2018 Rous Whipple Award.

Rio Bravo qWeek
Episode 227: Understanding DVT (Pidgin English)

Rio Bravo qWeek

Play Episode Listen Later Aug 7, 2026 21:17


Interview: Dr. Ozoemena: Welcome to today's podcast where we will be discussing an important health topic in a way that's easy to understand. I'm your host, Dr. Ozoemena. Today we're talking about Deep Vein Thrombosis, or DVT, a condition that affects thousands of people each year and can sometimes lead to serious complications if not recognized early. Joining us today is Dr. Okojie, a 3rd year Family Medicine Resident Physician. Thank you for being here today, Doctor. Dr. Okojie: Thank you for having me. I'm excited to discuss this important topic. What is DVT? Dr. Ozoemena: Let's start with the basics. What exactly is Deep Vein Thrombosis? Dr. Okojie: Deep Vein Thrombosis, or DVT, occurs when a blood clot forms in one of the deep veins of the body, most commonly in the legs. Normally, blood flows smoothly through our veins, but sometimes a clot can develop and block that flow. The biggest concern is that part of the clot can break off and travel to the lungs. This is called pulmonary embolism, which can be a medical emergency. Why Should People Know About DVT? Dr. Ozoemena: Why is it important for the public to be aware of DVT? Dr. Okojie: DVT is more common than many people realize. The symptoms can sometimes be mild or mistaken for other conditions. Early recognition is important because prompt treatment can prevent serious complications and improve outcomes. Many cases are preventable, especially when people understand the risk factors. Who Is at Risk? Dr. Ozoemena: Who is more likely to develop blood clots? Dr. Okojie: Several factors can increase the risk of DVT. These include: {Discuss Virchow triad: VEH - Venous stasis, Endothelial injury and Hypercoagulability} Being inactive for long periods, such as during long flights or car rides Recent surgery or hospitalization Cancer  Pregnancy and the weeks after childbirth Smoking Obesity A History of clotting disorders It's important to remember that having a risk factor doesn't mean someone will definitely develop a clot, but it does increase the chances. What Are the Symptoms? Dr. Ozoemena: What symptoms should people watch for? Dr. Okojie: The most common symptoms occur in one leg and may include: Swelling Pain or tenderness Warmth in the affected area Redness or discoloration of the skin Some people describe the pain as a cramp that doesn't go away. When Does It Become an Emergency? Dr. Ozoemena: You mentioned that a clot can travel to the lungs. What warning signs should prompt someone to seek emergency care? Dr. Okojie: That's a very important question. People should seek immediate medical attention if they experience: Sudden shortness of breath Chest pain, especially when taking a deep breath Rapid heartbeat Dizziness or fainting Coughing up blood These symptoms could indicate a pulmonary embolism, which requires urgent treatment. How Is DVT Diagnosed? Dr. Ozoemena: If someone visits their doctor with symptoms, how is DVT diagnosed? Dr. Okojie: The healthcare provider will first ask about symptoms and medical history. The most common test is the ultrasound of the leg. It's painless, noninvasive, and allows us to see whether blood flow is blocked by a clot. Sometimes a blood test called a D-dimer is also used to help determine whether further testing is needed. How Is DVT Treated? Dr. Ozoemena: Once a clot is diagnosed, what treatment options are available? Dr. Okojie: The primary treatment is medication known as anticoagulants for those with contraindications to anticoagulants, IVC filter is recommended These medications help prevent the clot from growing larger and reduce the risk of new clots forming. Treatment usually continues for at least several months, although the exact duration depends on the individual's situation and risk factors. Most patients do very well when treatment starts promptly. Can DVT Be Prevented? Dr. Ozoemena: That's encouraging. What can people do to reduce their risks? Dr. Okojie: There are several practical steps: Stay physically active Take walking breaks during long trips Stay well hydrated Maintain a healthy weight Avoid smoking Follow your healthcare provider's recommendations after surgery or hospitalization Common Misconceptions Dr. Ozoemena: Are there any common myths about DVT that you'd like to address? Dr. Okojie: One common misconception is that blood clots only affect older adults. While risk increases with age, DVT can occur in younger adults as well, especially if they have risk factors such as recent surgery, pregnancy, certain medications, or inherited clotting disorders. Another misconception is that leg swelling is always harmless. Persistent swelling, especially in one leg, should be evaluated by a healthcare professional. Key Take-Home Messages Dr. Ozoemena: Before we wrap up, what are the most important messages you'd like listeners to remember? Dr. Okojie: I'd emphasize three key points: First, know the symptoms—swelling, pain, warmth, and redness in one leg. Second, understand your personal risk factors, especially after surgery, hospitalization, long travel, or during pregnancy. And third, seek medical attention promptly if you have symptoms of DVT or signs of pulmonary embolism, such as sudden shortness of breath or chest pain. Early diagnosis and treatment can save lives. Dr. Okojie: Thank you for having me. I hope today's discussion helps listeners better understand DVT and recognize when to seek medical care. Dr. Ozoemena: And thank you to our listeners for joining us today. Remember, this podcast is intended for educational purposes and should not replace advice from your healthcare provider. Until next time, stay informed, stay healthy, and take care. This is Rio Bravo qWeek… signing off! Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week!  References: American Academy of Family Physicians. Venous Thromboembolism: Diagnosis and Management.  UpToDate. Overview of the Treatment of Lower Extremity Deep Vein Thrombosis (DVT). Updated September 2025.  American College of Chest Physicians. Antithrombotic Therapy for VTE Disease.  American Society of Hematology. Guidelines for Management of Venous Thromboembolism. Theme song, Works All The Time by Dominik Schwarzer, YouTube ID: CUBDNERZU8HXUHBS, purchased from https://www.premiumbeat.com/. Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week!

Connecting the Dots
Following Your Heart with Dr. Richard D. Mainwaring

Connecting the Dots

Play Episode Listen Later Aug 6, 2026 29:46


Richard Mainwaring, MD, has been a pediatric cardiac surgeon since 1990 and has been a faculty member at the Stanford University School of Medicine since 2003.During Dr. Mainwaring's career as a surgeon, he has contributed to this specialized field of surgery in many realms, including clinical medicine, basic science research, and publications. Dr. Mainwaring is a member of all four professional thoracic surgical organizations, including the American Association of Thoracic Surgery, Society for Thoracic Surgeons, Western Thoracic Surgical Association, and the Southern Thoracic Surgical Association and is also a member of the American College of Surgeons and Congenital Heart Surgeons' Society.In 2012, the congenital cardiac surgery fellowship program at Lucile Packard Children's Hospital (LPCH) received accreditation from the Accreditation Council for Graduate Medical Education. This program is one of 17 accredited congenital cardiac surgery training programs in the US. Dr. Mainwaring has been program director at LPCH since its inception and is currently Chairperson of the Congenital Thoracic Surgical Directors Association. Dr. Mainwaring teaches intra-operative management and surgical technique to the congenital cardiac surgery fellows.Link to claim CME credit: https://www.surveymonkey.com/r/3DXCFW3CME credit is available for up to 3 years after the stated release dateContact CEOD@bmhcc.org if you have any questions about claiming credit.

Diabetes Core Update
Special Edition: Hypertension Part I—Overview and Management

Diabetes Core Update

Play Episode Listen Later Aug 6, 2026 33:38


In the first episode of this special three-part series, Neil Skolnik speaks with Dr. Minesh Rajpal. Together, they provide an overview, discussing the assessment and management of high blood pressure. This special episode is sponsored with support from AstraZeneca. Presented by: Neil Skolnik, MD, Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health Minesh Rajpal, MD, Attending Nephrologist and Hypertension Specialist at the Southwest Kidney Institute References: 2025 AHA/ACC/AANP/AAPA/ABC/ACCP/ACPM/AGS/AMA/ASPC/NMA/PCNA/SGIM Guideline for the Prevention, Detection, Evaluation and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Joint Committee. Hypertension 2025; 82(10) Blood pressure lowering for prevention of cardiovascular disease and death: a systematic review and meta-analysis. Lancet 2016;387:957

ACTEC Trust & Estate Talk
Liability of Executors and Transferees for Estate Taxes

ACTEC Trust & Estate Talk

Play Episode Listen Later Aug 4, 2026 12:47


Can executors be personally liable for unpaid estate taxes? Learn how fiduciaries and transferees can reduce risk and avoid costly mistakes. The American College of Trust and Estate Counsel, ACTEC, is a professional society of peer-elected trust and estate lawyers in the United States and around the globe. This series offers professionals best practice advice, insights, and commentary on subjects that affect the profession and clients. Learn more in this podcast.

Dentistry Uncensored with Howard Farran
Dr. Samir Singh and Nancy Hairston : Dentistry Uncensored w/ Howard Farran #1722

Dentistry Uncensored with Howard Farran

Play Episode Listen Later Aug 3, 2026 54:28


In this two-guest episode, Howard Farran brings together two very different but complementary paths in reconstructive surgery. Nancy Hairston is the founder and CEO of MedCAD, a Dallas-based medical technology company specializing in patient-matched cranial, facial, and mandibular implants. A sculptor by training — with a fine arts degree and an early career designing toys for Mattel and Disney and building 3D animation software that became Maya — Nancy channeled her mastery of digital sculpting into medicine, earning FDA clearance for her AccuShape cranial implant in 2011 and delivering custom, patient-specific solutions for more than 8,000 individuals since. Dr. Samir Singh is a board-certified oral and maxillofacial surgeon and Fellow of the American College of Surgeons, trained at VCU in complex implant surgery, bone grafting, orthognathic surgery, and maxillofacial trauma, who now practices in North Pittsburgh, teaches and mentors residents, and lectures nationally on full-arch implant reconstruction. Together, the conversation walks through how custom implant design and surgical expertise intersect — the MedCAD process of turning precise imaging into a planned, in-house-manufactured implant delivered to surgical teams around the world, and how that planning removes friction, shortens procedure time, and boosts a surgeon's confidence before the first incision. Dr. Singh shares his journey from Pittsburgh to the operating room, the growth and technology behind his practice, and memorable orthognathic and reconstruction cases, along with his heart for mission work — including trips to treat children with cleft lip and palate in Peru. The episode closes on mentorship and the shadowing and hiring opportunities both guests see for the next generation of surgeons and innovators.   Episode #1722 : Dentistry Uncensored with Howard Farran, Howard sits down with two guests at the cutting edge of surgical reconstruction: Nancy Hairston, founder & CEO of MedCAD, and Dr. Samir Singh, board-certified oral and maxillofacial surgeon. From an artist-turned-medical-tech founder who's created patient-matched implants for 8,000+ people, to a surgeon rebuilding faces and jaws with full-arch and orthognathic expertise — this is a fascinating look at how custom design and surgical skill come together in the OR.

Financial Clarity for Doctors
Summer Planning Checklist

Financial Clarity for Doctors

Play Episode Listen Later Aug 3, 2026 29:47


It's summer!  Time for fun in the sun and extra time with friends and family, which can have an impact on the finances!  In this episode of Financial Clarity for Doctors, hosts Corey Janoff and Rachelle Vanderzanden walk through a few things that can be helpful during a mid-year financial planning check. Ideas for Summer Planning: Take a moment to review your spending and reflect on whether it matches up with those goals! Spent a lot of money on eating on travel, but travel is important to you? That might be just fine!  Everyone is different. Review progress toward making maximum retirement contributions (if you are able). Are you on track to make the maximum employee deferral contribution of $24,500 to your employer plan? Review your cash on hand to see if you have anything “extra” that can be put toward long-term goals. Can potentially add funds to 529 college savings accounts, 530A (Trump Accounts), or other investment accounts, depending on your goals. Go through your workplace benefits to ensure you are using them! Unused vacation days that may expire? Flexible Spending Account balances that need to be used? Potentially make some strategic tax planning moves depending on your circumstances. Example: Roth conversions add funds to your taxable income in the year converted, but then funds can grow tax free if used for qualified retirement withdrawals. Do a quick risk review – For example do you have adequate insurance and an estate plan drafted? You can review your finances any time of year, but the summer can be a great mid-year reset.  Sit back and relax on your deck with a cold beverage and lots of numbers!  Sounds like fun to us! For more financial planning tips from Corey and Rachelle, find them on social media! LinkedIn: @CoreyJanoff; Instagram: @CoreyJanoff and @VanderzandenRachelle; and Twitter: @CoreyJanoffCFP Discussions in this show should not be construed as specific recommendations or investment advice. Always consult with your investment professional before making important investment decisions. Securities and advisory services offered through LPL Financial, a registered investment advisor, Member FINRA/SIPC.  Finity Group, LLC is a separate entity from LPL Financial.  Finity Group and LPL Financial do not provide legal advice or tax services.  Please consult your legal advisor or tax advisor regarding your specific situation. This material is for general information and educational purposes only and is not intended to provide specific advice or recommendations for any individual. Investing involves risk including the loss of principal. There is no assurance that the views or strategies discussed are suitable for all investors or will yield positive outcomes. A Roth IRA conversion—sometimes called a backdoor Roth strategy—is a way to contribute to a Roth IRA when income exceeds standard limits. The converted amount is treated as taxable income and may affect your tax bracket. Federal, state, and local taxes may apply. If you're required to take a minimum distribution in the year of conversion, it must be completed before converting. To qualify for tax-free withdrawals, you must generally be age 59½ and hold the converted funds in the Roth IRA for at least five years. Each conversion has its own five-year period, and early withdrawals may be subject to a 10% penalty unless an exception applies. Income limits still apply for future direct Roth IRA contributions. This material is for informational purposes only and does not constitute tax, legal, or investment advice. Please consult a qualified tax professional regarding your individual circumstances. Prior to investing in a 529 Plan investors should consider whether the investor's or designated beneficiary's home state offers any state tax or other state benefits such as financial aid, scholarship funds, and protection from creditors that are only available for investments in such state's qualified tuition program. Withdrawals used for qualified expenses are federally tax free. Tax treatment at the state level may vary. Please consult with your tax advisor before investing.​ Trump Accounts offer tax deferred growth on earnings. Family contributions are made with after tax dollars, and eligible employer contributions may be excluded from the employee's taxable income. A one time $1,000 federal contribution may be available for eligible children born between 2025 and 2028. Distributions are generally prohibited during the child's growth period and, once permitted, are taxable as ordinary income and may be subject to a 10% IRS early distribution penalty if taken before age 59½. Contribution limits and other restrictions apply, and some rules remain subject to future Treasury and IRS guidance. Consult a qualified tax advisor or financial professional before making decisions. Rebalancing a portfolio may cause investors to incur tax liabilities and/or transaction costs and does not assure a profit or protect against a loss.​ Finity Group and LPL Financial do not provide legal advice or tax services. Please consult your legal advisor or tax advisor regarding your specific situation. Citations: Internal Revenue Service.  Frequently asked questions on gift taxes. https://www.irs.gov/businesses/small-businesses-self-employed/frequently-asked-questions-on-gift-taxes. Internal Revenue Service.  Charitable contribution deductions.. https://www.irs.gov/charities-non-profits/charitable-organizations/charitable-contribution-deductions. Trump Accounts. https://trumpaccounts.gov/. Bart, Susan T. and Connie T Eyster.  What is a Trump Account? Rules, Taxes, and How They Work for Families. https://www.actec.org/resource-center/video/trump-accounts-explained/. 2026. The American College of Trust and Estate Counsel.

Boardroom Governance with Evan Epstein
Sandra Gobert: European Governance in a Changing World

Boardroom Governance with Evan Epstein

Play Episode Listen Later Aug 3, 2026 60:26


(0:00) About the Boardroom Governance Summit (Aug 26-27, 2026)  (1:20) Intro (2:45) About the podcast sponsor: The American College of Governance Counsel. (3:31) Start of interview.  (4:55) Origin Story of Sandra Gobert (6:04) Sandra's Career Path (8:56) Guberna and Board Education. Member of EcoDa. (12:00) Family Firms and Control in EU (13:53) Relationship Agreements Explained (examples, Bpost and Proximus) (19:05) State Owned Enterprises (SOEs), and Government involvement on Boards (19:58) The Board's Emerging Fourth Role: advocacy and policymaking, alongside its traditional strategic, leadership, and oversight responsibilities. (22:52) AI and Alternative Structures. PBCs, Foundations, and other European multi-stakeholder models. (29:25) Employees on the Board ("unacceptable in Belgium"). (31:01) Toward European Harmonization ("We need more Europe, not less Europe") (31:50) The EU Inc. Idea (33:57) Principle-Based Governance ("Comply or Explain" framework) (36:19) The Value of Board Evaluations (41:05) Founder Control in Tech (dual class share structures) (44:05) Europe's Power Shift  (46:34) China and Global Competition (49:42) Europe's Economic Pressures (reference to The Economist's interview with Elon Musk) (52:23) Board Dynamics Matter (53:19) Books that have greatly influenced her life: Catherine de Médicis, ou, La reine noire, by Jean Orieux (1986) Passion, by Jude Morgan (2005) The Journey of Leadership by Hans-Werner Kaas, Dana Maor, Kurt Strovink, Ramesh Srinivasan (2024) (54:59) Her mentors.  (55:52) Quotes that she thinks of often or lives her life by.  (57:09) An unusual habit or an absurd thing that she loves.  (58:05) The living person she most admires in governance: Christine Lagarde. Sandra Gobert is the Executive Director of GUBERNA. Sandra also serves as an independent director of Fluxys Belgium, sits on the board of ecoDa, the European Confederation of Directors Associations, and is a member of the board of Belgium's Corporate Governance Committee. You can follow Evan on social media at:X: @evanepsteinLinkedIn: https://www.linkedin.com/in/epsteinevan/ Substack: https://evanepstein.substack.com/__To support this podcast you can join as a subscriber of the Boardroom Governance Newsletter at https://evanepstein.substack.com/__Music/Soundtrack (found via Free Music Archive): Seeing The Future by Dexter Britain is licensed under a Attribution-Noncommercial-Share Alike 3.0 United States License

KQED’s Forum
More California Kids Are Getting Hurt on E-Bikes, Study Finds

KQED’s Forum

Play Episode Listen Later Jul 31, 2026 54:45


E-bike crashes and injuries in California are increasing, a new study out of UC San Diego finds. And those injuries are not only more severe compared with conventional bikes, they'redisproportionately involving kids age 14 and younger. We'll hear how doctors, lawmakers andbiking advocates are responding to the risks posed by e-bikes – and by what some call emotorcycles – and we'll hear your takes about how we can make our roads safer for all. Guests: Azul Dahlstrom-Eckman, reporter, KQED Asha Weinstein Agrawal, professor and researcher, Mineta Transportation Institute at San Jose State University John Maa, governor and former president, American College of Surgeons; former trauma surgeon, MarinHealth Medical Center; co-author of the new study from UCSD, “An exponential increase in e-bike injuries in California” Learn more about your ad choices. Visit megaphone.fm/adchoices

Phoenix Cast
Abortion Access, Reproductive Coercion, and Survivor Autonomy Part 2

Phoenix Cast

Play Episode Listen Later Jul 30, 2026 28:32 Transcription Available


In part 2 of this episode of The Phoenix Cast, Violence Prevention Educator Cassandra Carmona-Wayman (she/hers/ella) continues her conversation with reproductive health advocate Cristina Ponce (she/hers) about Abortion Access, Reproductive Coercion, and Survivor Autonomy. Cristina shares her abortion story and shares her lived experiences with these topics. We also unpack how shifting laws, financial barriers, and crisis pregnancy centers impact survivor autonomy and safety. We highlight practical resources like abortion funds, doulas, travel support, and trusted clinic locators. We also break down myths about medication abortion and centering abortion as both healthcare and a crucial safety option for survivors of violence.Content warnings: discussion of abortion (including personal and self-managed abortion stories), reproductive coercion, intimate partner and interpersonal violence, sexual violence (including rape and sexual coercion), pregnancy-related homicide risk, and anti-abortion harassment/misinformation.Additionally:We discuss healthcare clinics and abortion providers near the Denver Metro area. Please be aware of clinics that misrepresent their services and can appear misleading to patients in need of care. Some “crisis pregnancy centers” near campus and in Denver are not medical clinics and may offer misleading or incomplete information about abortion and pregnancy options. When you can, seek licensed providers or clinics that clearly offer full-spectrum reproductive healthcare, and remember you can reach out to the Phoenix Center at Auraria for confidential support and accurate referrals.Sources and Resources mentioned in the episode:American College of Obstetricians and Gynecologists. Committee Opinion No. 554: Reproductive and Sexual Coercion. American College of Obstetricians and Gynecologists, 2013.American College of Obstetricians and Gynecologists. “Reproductive and Sexual Coercion.” ACOG, Feb. 2013,  https://www.acog.org/clinical/clinical-guidance/committee-opinion/articles/2013/02/reproductive-and-sexual-coercion.Centers for Disease Control and Prevention. “About Violence and Pregnancy.” Centers for Disease Control and Prevention,  https://www.cdc.gov/intimate-partner-violence/about/violence-and-pregnancy.html.Centers for Disease Control and Prevention. “Pregnancy Resulting from Sexual Violence.” Centers for Disease Control and Prevention,  https://www.cdc.gov/sexual-violence/about/pregnancy-resulting-from-sexualviolence.html.Cobalt Abortion Fund. Cobalt Abortion Fund,  https://cobaltaf.org/.Colorado Doula Project. Colorado Doula Project,  https://www.coloradodoulaproject.org/.Foster, Diana Greene. The Turnaway Study: Ten Years, a Thousand Women, and the Consequences of Having—or Being Denied—an Abortion. Scribner, 2020.Grace, Kelsey T., and Julie C. Anderson. “Reproductive Coercion: A Systematic Review.” Journal of Midwifery & Women's Health, vol. 63, no. 4, 2018, pp. 371–84.Guttmacher Institute. U.S. Abortion Patient and Policy Reports. Guttmacher Institute, https://www.guttmacher.org.Miller, Elizabeth, et al. “Pregnancy Coercion, Intimate Partner Violence and Unintended Pregnancy.” Contraception, vol. 81, no. 4, 2010, pp. 316–22.National Abortion Federation. National Abortion Federation,  https://prochoice.org/.National Academies of Sciences, Engineering, and Medicine. The Safety and Quality of Abortion Care in the United States. National Academies Press, 2018.“North Carolina Bill Would Authorize Deadly Force for Women Seeking Abortions.” WCNC Charlotte,  https://www.wcnc.com/article/news/politics/north-carolina-politics/north-carolina-bill-would-authorize-deadly-force-for-women-seeking-abortions/275-353d54a3-9231-4341-ae44-a127546db76f.Raymond, Elizabeth G., and David A. Grimes. “The Comparative Safety of Legal Induced Abortion and Childbirth in the United States.” Obstetrics & Gynecology, vol. 119, no. 2, 2012, pp. 215–19.“Reproductive Coercion.” The National Domestic Violence Hotline,  https://www.thehotline.org/resources/reproductive-coercion/.“Reproductive Coercion: What Is It?” Teen Vogue,  https://www.teenvogue.com/story/what-is-reproductive-coercion.Sexual Assault Awareness Fund. “Bisexual Women Are More Likely to Have Abortions.” Sexual Assault Awareness Fund, https://saafund.org/bisexual-women-are-more-likely-to-have-abortions/.Society of Family Planning. #WeCount Reports on Abortion Access After Dobbs.Society of Family Planning,  https://societyfp.org/.Tarzia, Laura, et al. “Reproductive Coercion and Abuse: A Systematic Review of Qualitative Evidence.” Trauma, Violence, & Abuse,  https://pmc.ncbi.nlm.nih.gov/articles/PMC5819992/.Van Parys, An-Sofie, et al. “Prevalence and Evolution of Intimate Partner Violence before and during Pregnancy: A Cross-Sectional Study.” BMC Pregnancy and Childbirth, vol. 14, 2014, article 294,  https://doi.org/10.1186/1471-2393-14-294.Washington State Coalition Against Domestic Violence. Pregnancy and Domestic Violence Issue Brief. Washington State Coalition Against Domestic Violence, 2013,  https://wscadv.org/wp-content/uploads/2016/12/pregnancy-dvfr-issue-brief-12-2013.pdf.World Health Organization. Abortion Care Guideline. World Health Organization, 2022.You can learn more about your options with healthcare service providers like Just the Pill. They can provide vital information and assistance with abortion, contraception, and other sexual and reproductive health services. We provide efficient and equitable access to health care by telemedicine. https://justthepill.com/about-us/You can also look into resources like Elevated Access. They are a nonprofit organization that provides free air transportation through a network of volunteer pilots, helping people travel to essential healthcare services they might not otherwise be able to reach. Their services primarily support access to abortion care and gender-affirming care by coordinating safe, confidential flights in partnership with healthcare and advocacy organizations across the United States.Be aware of Denver Metro Crisis Pregnancy Centers (CPCs):The AVI Project https://www.theaviproject.com/Alternatives Pregnancy Center (Alternatives Colorado) https://youhavealternatives.org/Bella Health and Wellness. Bella Health and Wellness.  https://bellahealthandwellness.com/.Alternatives Pregnancy Center. Alternatives Pregnancy Center.  https://youhavealternatives.org/.Marisol Health. Marisol Health.  https://marisolhealth.com/.Life Choices. Life Choices.  https://lifechoices.org/.If you are in crisis and need immediate support, please call our 24/7 interpersonal violence helpline at 303-556-2255.Request an Appointment with an Advocate athttps://www.thepca.org/online-appointment-requestRequest a Violence Prevention Presentation at https://www.thepca.org/prevention-educationInstagram @phoenixauraria

Lab Rat Chat
38. Translational Conversations Ep. 4 - Love, Loss, and the Treatment of Prolonged Grief

Lab Rat Chat

Play Episode Listen Later Jul 29, 2026 45:20


Send us Fan MailThis week on Translational Conversations, we talk with Dr. Zoe Donaldson, a prairie vole researcher, and Dr. Katherine Shear, a human researcher, about how their work has inspired and influenced each other's research on attachment bonding, love and loss, and the development of Prolonged Grief Disorder. In this episode, Dr. Donaldson and Dr. Shear discuss the role of the brain's reward system in grief, how grief differs from depression, the special bonding of prairie voles that makes them an ideal species for studying grief, and how their complementary research has inspired novel treatments for Prolonged Grief Disorder. Their discussion further explores the bidirectional process of translational research, how to consider the language we use when communicating findings from different species, and ways we can build better bonds between researchers to advance scientific progress. We thank Dr. Zoe Donaldson, the Larry Gold Professor in the Department of Molecular, Cellular, and Developmental Biology and the Department of Psychology and Neuroscience at the University of Colorado Boulder and Dr. Katherine Shear, the Marion E. Kenworthy Professor of Psychiatry at Columbia University and the founding Director of the Center for Prolonged Grief at Columbia School of Social Work, for their openness and willingness in discussing their research with us for this podcast.Translational Conversations is made possible through support from Biomedical Research Awareness Day, a program of Americans for Medical Progress and the American College of Neuropsychopharmacology.Resources & Links: Craving Love? Enduring grief activates brain's reward center by Mary-Frances O'ConnorNeurobiology and treatment advances for prolonged grief disorder by Donaldson and ShearPrairie Voles as a model of adaptive reward remodeling following loss of a bonded partner by Sadino and Donaldson Support the showFollow Lab Rat Chat on X! Facebook! Instagram!https://twitter.com/thelabratchat https://www.facebook.com/labratchat https://www.instagram.com/thelabratchat All Lab Rat Chat episodes are edited by Audionauts: https://audionauts.pro/ 

The Gary Null Show
The Gary Null Show - 7-27-26

The Gary Null Show

Play Episode Listen Later Jul 27, 2026 64:04


HEALTH NEWS   Berberine Shows Beneficial Effects on Metabolic Health, Study Reports Cooperation beats selfishness more often than scientists thought Sleep Disorders Don't Just Exhaust You. New Research Shows They Change Your Brain Two Hours of Strength Training Weekly Linked to Lower Heart Attack Risk in Women, Study Finds Planetary Health Diet lowers cardiovascular risk in older women     Berberine Shows Beneficial Effects on Metabolic Health, Study Reports Peking Union Medical College (China), July 24 2026 (Natural News)     A review published in the journal Molecules has summarized evidence indicating that berberine, a compound found in several plants, may influence glucose and lipid metabolism. According to the review, berberine has been associated with improvements in metabolic health markers across multiple studies. The compound is a yellow alkaloid extracted from plants such as European barberry, goldenseal, goldthread, Oregon grape, and tree turmeric. The review cited evidence that berberine may reduce blood glucose levels and improve insulin sensitivity, according to clinical trials. A systematic review of seven randomized clinical trials from China published in Nutrients revealed that berberine consistently alters the composition of gut bacteria in patients taking the supplement, and the analysis examined data across conditions including Type 2 diabetes, high cholesterol, and colorectal adenoma. Lipid panel improvements, including lower total cholesterol and triglycerides, were also reported in the reviewed studies.   Cooperation beats selfishness more often than scientists thought Hebrew University of Jerusalem & Rutgers University, July 20 2026 (Eureaklert)  For decades, one of the most influential ideas in evolutionary biology has suggested that when individuals act purely in their own self-interest, cooperation should eventually collapse. But a new study by the Hebrew University of Jerusalem and Rutgers University demonstrates that evolution may be far more optimistic than previously believed. Their findings reveal that cooperation does not require close family ties, reputation, repeated favors, or rigid social structures. Instead, cooperation can flourish simply because individuals respond differently to different opponents. The research proposes a new solution to one of biology's oldest puzzles: how cooperation survives in a world shaped by natural selection. Using mathematical models, evolutionary simulations, and populations of artificial intelligence agents, the researchers found that cooperation consistently evolved when individuals adjusted their willingness to cooperate according to whom they encountered. Rather than treating everyone identically, simple opponent-specific responses created stable communities in which cooperative behavior repeatedly outperformed purely selfish strategies. Perhaps the study's most surprising finding is that cooperative societies are not fragile exceptions. Across thousands of simulations, populations repeatedly evolved toward highly cooperative states, while purely selfish populations often failed to dominate. Even when mutations introduced new defectors, cooperative communities remained remarkably resilient.   Sleep Disorders Don't Just Exhaust You. New Research Shows They Change Your Brain Florida International University, July 26, 2026 (SciTech Daily) A poor night's sleep can affect far more than energy the next day. Research from Florida International University links sleep disorders with structural differences in brain regions that help control attention, motivation and decision-making. Published in the journal Scientific Reports, the findings provide one of the broadest comparisons yet of how different sleep disorders are associated with the brain.  The researchers compared two broad categories. Dyssomnias, such as insomnia and sleep apnea, interfere with falling asleep or remaining asleep. Parasomnias, including sleepwalking, nightmare disorder and sleep terrors, involve unusual events that disrupt the sleep cycle. Both categories were associated with decreases in the thalamus, a region that filters incoming information, supports concentration, and contributes to higher-level thinking. The researchers identified changes specifically in the pulvinar, an area within the thalamus that directs attention and helps manage cognitive control. These differences were connected with wider brain networks that support concentration and task performance. That pattern may help explain why disrupted sleep is associated with slower reactions, poorer decision-making and a greater likelihood of errors and accidents.   Two Hours of Strength Training Weekly Linked to Lower Heart Attack Risk in Women, Study Finds Harvard School of Public Health, July 26 2026 (Natural News) A large-scale study published in the Journal of the American College of Cardiology has found that women who engage in regular strength training have a significantly lower risk of developing cardiovascular disease. The study examined data from 117,025 women over an average follow-up period of 14.5 years.   Women who performed any amount of resistance training had a lower risk of cardiovascular events compared with those who did none. The association persisted after adjusting for overall lifestyle and health factors, the study stated.  Among the study's specific findings, women who performed at least two hours of resistance training per week had a 44% lower risk of heart attack relative to women who did no resistance training, the report said. Any cardiovascular disease risk was 20% lower for that group, with an additional 5% reduction per extra hour of weekly resistance training, according to the study. The benefits of strength training were more pronounced among women who maintained resistance training consistently and trained both upper and lower body, according to the study. Adding strength training to regular aerobic exercise – such as walking or running – was linked to better heart health.   Planetary Health Diet lowers cardiovascular risk in older women University of Caliornia at Irvine, July 25 2026 (News-Medical) A 20-year study of more than 65,000 postmenopausal women found that higher adherence to the Planetary Health Diet was associated with a lower risk of overall cardiovascular disease, coronary heart disease, stroke and heart failure. The findings showed that women whose diet most closely followed the Planetary Health Diet had about a 28% lower risk of cardiovascular disease compared with women in the group scoring the lowest for adherence. However, even moderate adherence to the diet was linked with lower risk. The Planetary Health Diet emphasizes foods such as fruits, vegetables, whole grains, legumes, nuts and unsaturated fats while limiting foods such as red and processed meats, added sugars, refined grains and saturated fats. The investigators followed 66,892 participants in the Women's Health Initiative (WHI).  Overall, the results showed that women in the group whose diets were more closely aligned with the Planetary Health Diet had the lowest risk of cardiovascular disease. These women also showed a decreased risk of heart disease, heart failure and stroke risk compared to the women in the lowest-adherence group. However, even moderate adherence to the diet was associated with a decrease in risk, with each 10-point increase in Planetary Health Diet Index score linked to further risk reduction.

The mindbodygreen Podcast
660: Why adding more to your diet beats eliminating | Wendy Bazilian, DrPH, MA, RDN

The mindbodygreen Podcast

Play Episode Listen Later Jul 26, 2026 42:54


"The diet you'll stay on is a diet that's enjoyable and not too hard,” says Wendy Bazilian, DrPH, MA, RDN.  Bazilian is a Registered Dietitian Nutritionist, American College of Sports Medicine Certified Exercise Physiologist, and Doctor of Public Health. She's authored multiple bestselling books, as well as contributed to a New York Times bestseller and a James Beard-nominated cookbook. She's a spokesperson for Avocados – Love One Today and she's a frequent nutrition expert cited in mindbodygreen articles.  This podcast is sponsored by Avocados - Love One Today®. Visit LoveOneToday.com for free nutrition resources backed by science and tasty recipes to help you find new ways to add more avocado to your plate, whether it's breakfast, lunch, a snack or dinner.   00:00 - The value of the food we consume 03:06 - Why dietary fat was misunderstood for decades 07:47 - Nutrient density vs. calorie counting 09:56 - Why 94% of us fall short on fiber 14:26 - Heart health, satiety, & blood sugar control 16:48 - Why the best diet is one you enjoy 18:50 - Food synergy & nutrient absorption 21:51 - Unexpected ways to cook with avocados 26:58 - The glycemic load effect 31:28 - Serving size vs. portion size 35:41 - How to store avocados properly 40:06 - 3 rules for moving the needle on health Referenced in the episode:  The HAT trial: https://pubmed.ncbi.nlm.nih.gov/34496276/  Glycemic load study: https://www.sciencedirect.com/science/article/pii/S2475299126000557  For more about Bazilian, visit her website: https://www.wendybazilian.com/  We hope you enjoy this episode, and feel free to watch the full video on YouTube! Whether it's an article or podcast, we want to know what we can do to help here at mindbodygreen. Let us know at: podcast@mindbodygreen.com. Learn more about your ad choices. Visit megaphone.fm/adchoices

Optimal Health Daily
3476: What Are The Health Benefits of Saunas and Cold Showers on Evidence-Based Health

Optimal Health Daily

Play Episode Listen Later Jul 24, 2026 9:44


Get the 200+ Page Optimal Living Daily Workbook (PDF) — Free. Want to turn today's episode into an actionable plan? Join the Optimal Living Weekly newsletter and I'll send you our 200-page digital workbook immediately. It's packed with the best takeaways from the show, formatted for easy reading and implementation at home. Get your free PDF workbook here: ⁠⁠https://oldpodcast.eo.page/join⁠ Discover all of the podcasts in our network, search for specific episodes, get the Optimal Living Daily workbook, and learn more at: OLDPodcast.com. Episode 3476: Dr. Neal Malik answers a listener's question about whether saunas and cold showers are worth prioritizing for better health and longevity, separating popular claims from what the research actually supports. He explains why traditional steam saunas appear to offer cardiovascular and other health benefits for many people, while the current evidence for cold water immersion is much weaker and may even suggest potential downsides. Quotes to ponder: "When we spend time in the environments I just described or really when we're exposed to a lot of heat our bodies respond by dilating our blood vessels which means the inner lining of our blood vessels get bigger." "Some researchers have found that regular use of saunas may decrease pain levels in those experiencing chronic pain like those that suffer from arthritis." "The reason you hear so much about the benefits of antioxidants is because they help our bodies get rid of free radicals." Episode references: American College of Sports Medicine: https://www.acsm.org/ Bastyr University California: https://bastyr.edu/ Learn more about your ad choices. Visit megaphone.fm/adchoices

Cardionerds
459. The Continuum of Prevention and Heart Failure with Dr. Anu Lala and Dr. Martha Gulati

Cardionerds

Play Episode Listen Later Jul 23, 2026 26:30


CardioNerds (Drs. Apoorva Gangavelli, Jenna Skowronski, and Hannah Every) discuss the continuum of prevention and heart failure with Drs. Anu Lala and Martha Gulati. Grounded in a clinical case of a 55-year-old woman with uncontrolled hypertension, type 2 diabetes, and obesity who is on the trajectory toward heart failure, this episode unpacks a paradigm-shifting framework from a joint HFSA/ASPC Scientific Statement. The discussion explores how prevention should not be siloed from heart failure management but rather integrated across a patient’s lifespan—from primary prevention in at-risk individuals, to secondary prevention in those with established heart failure, to tertiary prevention in patients with advanced therapies such as LVADs and heart transplantation. The experts highlight the importance of aggressive risk factor management, biomarker-guided screening, the AHA’s Life’s Essential 8, and the need for multidisciplinary collaboration and systems-level change to shift heart failure care from reactive to proactive. Audio editing for this episode was performed by CardioNerds Intern, Dr. Julia Marques Fernandes. Enjoy this Circulation 2022 Paths to Discovery article to learn about the CardioNerds story, mission, and values. US Cardiology Review is now the official journal of CardioNerds! Submit your manuscript here. CardioNerds Prevention PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Pearls Systemic inflammatory diseases are associated with an elevated CVD risk that has significant implications for early detection, risk Heart failure prevention is a continuum, not a checkpoint. Prevention applies at every stage—from at-risk (Stage A) through advanced/post-transplant care—and every clinical encounter is an opportunity to intervene. The AHA’s Life’s Essential 8 (diet, physical activity, nicotine exposure, sleep, BMI, blood lipids, blood glucose, blood pressure) forms the foundation at every stage. Hypertension carries the highest population-attributable risk for heart failure of any modifiable risk factor. In the Framingham Heart Study, 91% of patients with newly diagnosed HF had pre-existing hypertension. The SPRINT trial demonstrated a 38% reduction in HF incidence with intensive blood pressure targets (30 ng/L or NT-proBNP >125 ng/L) identify individuals at heightened risk for progression to symptomatic HF. The ACC/AHA/HFSA guidelines give a Class IIa recommendation for natriuretic peptide screening in at-risk patients. Urine albumin-to-creatinine ratio (UACR) is an underutilized screening tool that provides additional insight into CKM risk. The heart failure label does not close the prevention window—it accentuates it. Secondary prevention through GDMT optimization (quadruple therapy in HFrEF) and continued risk factor management remains critical. Tertiary prevention extends to post-LVAD and post-transplant patients, where hypertension, diabetes, obesity, and CKD management remain essential to long-term outcomes. Show notes For a comprehensive review, please review the full HFSA/ASPC Joint Scientific Statement: Lala A, Beavers C, Blumer V, et al. The Continuum of Prevention and Heart Failure in Cardiovascular Medicine. J Card Fail. 2026;32:75-105. doi:10.1016/j.cardfail.2025.06.013 1. What is the “continuum of prevention” framework, and how does it differ from traditional approaches to heart failure prevention? Historically, prevention and heart failure management have been treated as separate disciplines—primary prevention handled by preventive cardiologists and treatment managed by heart failure specialists. This joint HFSA/ASPC Scientific Statement reframes prevention as a dynamic, continuous process that spans a patient’s entire lifespan, regardless of HF stage or ejection fraction. The framework maps onto the ACC/AHA HF staging system: Primary prevention targets Stage A (“at risk”) and Stage B (“pre-HF”) patients to reduce the burden of incident HF. Secondary prevention targets Stage C (symptomatic) and Stage D (advanced) patients to reduce the impact of established HF through GDMT optimization and ongoing risk factor management. Tertiary prevention encompasses risk factor management in patients with LVADs or heart transplants—populations where hypertension, diabetes, and obesity still drive outcomes. The Central Figure of the statement illustrates that Life’s Essential 8 (blood pressure and lipid control, diabetes management, exercise, sleep, smoking cessation, weight management, and diet/nutrition counseling) forms the foundation at every stage, with pharmacologic and device-based therapies layered on top as disease progresses (Figure) 2. How do traditional risk factors drive heart failure, and what should clinicians prioritize? Hypertension carries the greatest population-attributable risk for HF. In the Framingham Heart Study (N=5,143), HTN was associated with a 2- to 3-fold increased risk of HF, with a population-attributable risk of 39% in men and 59% in women. The SPRINT trial showed a 38% reduction in HF incidence and 25% reduction in the primary composite outcome with intensive BP targets (30 ng/L or NT-proBNP >125 ng/L) are associated with heightened risk for progression to symptomatic HF. In the ARIC study, incorporating NT-proBNP reclassified 20% of older adults without HF into Stage B. Factors that affect interpretation include age, sex, obesity (lower values), and CKD (higher values). High-sensitivity cardiac troponin (hs-cTn): Concentrations above the 99th percentile are now included in the definition of Stage B HF. Troponin testing may complement natriuretic peptides, particularly when BNP/NT-proBNP values are ambiguous. Risk scores: The PCP-HF equation predicts 10-year HF risk using traditional risk factors plus QRS duration. The AHA PREVENT score incorporates HF risk calculation and includes markers of kidney function (albuminuria, eGFR), though it may underestimate risk in men and Black adults. The CKM syndrome staging framework (Stages 0–4) provides a holistic approach to assessing systemic cardiovascular-kidney-metabolic risk. 4. What are the key nontraditional risk factors and cross-cutting themes in heart failure prevention? Genetics: Pathogenic cardiomyopathy variants exist in ~1 in 200 individuals in the general population. The HFSA and ACMG recommend cascade testing to identify at-risk family members. Polygenic risk scores for dilated cardiomyopathy show a 3.8-fold risk for DCM in the top 10th percentile compared with the median. Sex-specific considerations: Women have 2.8 times the odds of developing HFpEF, while men have similarly increased odds of HFrEF. A complete obstetric/gynecologic history is essential—preeclampsia is associated with a 4-fold increased risk of HF. Peripartum cardiomyopathy requires intentional screening in high-risk populations. Cardiotoxic exposures: Clinicians should be aware of medications that cause direct myocardial toxicity (e.g., anthracyclines, trastuzumab, tyrosine kinase inhibitors). A team-based approach with pharmacists can help optimize medication selection and risk factor modification. Social determinants of health: Environmental exposures (air pollution, arsenic, lead, cadmium), food insecurity, financial instability, and limited healthcare access contribute to HF risk and progression. Equity-focused, risk-based prevention strategies are needed. Psychological health: Depression is common in HF and independently associated with worse outcomes. Screening with brief questionnaires (e.g., PHQ-2) is recommended. Meditation, spirituality, and holistic wellness approaches remain underutilized. 5. What systems-level and policy changes are needed to move the needle on heart failure prevention? Multidisciplinary HF prevention clinics that bring together preventive cardiologists, HF specialists, endocrinologists, nephrologists, dietitians, pharmacists, exercise physiologists, and genetic counselors are advocated by the statement. EHR-embedded risk stratification could proactively flag patients on a trajectory toward HF—analogous to sepsis alerts or fall risk flags—enabling earlier intervention, particularly for patients who may not reach a cardiologist. Cardiac rehabilitation remains underutilized, particularly in HFrEF (Class 2b recommendation) and HFpEF (not yet covered by Medicare). The HF-ACTION trial showed quality-of-life benefits, and the REHAB-HF trial showed particular benefit in older patients with HFpEF. Policy priorities include expanding insurance coverage for preventive screening and novel therapies (SGLT2i, GLP-1 RAs, nsMRAs), reducing clinical inertia through team-based care models with closer follow-up intervals, and ensuring equitable access to evidence-based therapies across diverse populations. Digital health and AI hold promise for personalized risk prediction, remote monitoring (e.g., wearable devices, implantable PA pressure monitors), and virtual cardiac rehabilitation to overcome access barriers. Figure  Lala A, Beavers C, Blumer V, et al. The continuum of prevention and heart failure in cardiovascular medicine: a joint scientific statement from the Heart Failure Society of America and the American Society for Preventive Cardiology. J Card Fail. 2026;32(1):75-105. doi:10.1016/j.cardfail.2025.06.013) References Key references are bolded. Lala A, Beavers C, Blumer V, et al. The continuum of prevention and heart failure in cardiovascular medicine: a joint scientific statement from the Heart Failure Society of America and the American Society for Preventive Cardiology. J Card Fail. 2026;32(1):75-105. doi:10.1016/j.cardfail.2025.06.013 Heidenreich PA, Bozkurt B, Aguilar D, et al. 2022 AHA/ACC/HFSA guideline for the management of heart failure: a report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation. 2022;145(18):e895-e1032. doi:10.1161/CIR.0000000000001063 Lloyd-Jones DM, Allen NB, Anderson CAM, et al. Life’s Essential 8: updating and enhancing the American Heart Association’s construct of cardiovascular health: a presidential advisory from the American Heart Association. Circulation. 2022;146(5):e18-e43. doi:10.1161/CIR.0000000000001078 SPRINT Research Group, Wright JT Jr, Williamson JD, et al. A randomized trial of intensive versus standard blood-pressure control. N Engl J Med. 2015;373(22):2103-2116. doi:10.1056/NEJMoa1511939 Levy D, Larson MG, Vasan RS, Kannel WB, Ho KK. The progression from hypertension to congestive heart failure. JAMA. 1996;275(20):1557-1562. doi:10.1001/jama.1996.03530440037034 Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). JAMA. 2002;288(23):2981-2997. doi:10.1001/jama.288.23.2981 Yusuf S, Sleight P, Pogue J, et al. Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. N Engl J Med. 2000;342(3):145-153. doi:10.1056/NEJM200001203420301 Zinman B, Wanner C, Lachin JM, et al. Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes. N Engl J Med. 2015;373(22):2117-2128. doi:10.1056/NEJMoa1504720 Anker SD, Butler J, Filippatos G, et al. Empagliflozin in heart failure with a preserved ejection fraction. N Engl J Med. 2021;385(16):1451-1461. doi:10.1056/NEJMoa2107038 Solomon SD, McMurray JJV, Claggett B, et al. Dapagliflozin in heart failure with mildly reduced or preserved ejection fraction. N Engl J Med. 2022;387(12):1089-1098. doi:10.1056/NEJMoa2206286 Filippatos G, Anker SD, Agarwal R, et al. Finerenone reduces risk of incident heart failure in patients with chronic kidney disease and type 2 diabetes: analyses from the FIGARO-DKD trial. Circulation. 2022;145(6):437-447. doi:10.1161/CIRCULATIONAHA.121.057983 Solomon SD, McMurray JJV, Vaduganathan M, et al. Finerenone in heart failure with mildly reduced or preserved ejection fraction. N Engl J Med. 2024;391(16):1475-1485. doi:10.1056/NEJMoa2407107 Lincoff AM, Brown-Frandsen K, Colhoun HM, et al. Semaglutide and cardiovascular outcomes in obesity without diabetes. N Engl J Med. 2023;389(24):2221-2232. doi:10.1056/NEJMoa2307563 Deanfield J, Verma S, Scirica BM, et al. Semaglutide and cardiovascular outcomes in patients with obesity and prevalent heart failure: a prespecified analysis of the SELECT trial. Lancet. 2024;404(10454):773-786. doi:10.1016/S0140-6736(24)01498-3  Kosiborod MN, Abildstrøm SZ, Borlaug BA, et al. Semaglutide in patients with heart failure with preserved ejection fraction and obesity. N Engl J Med. 2023;389(12):1069-1084. doi:10.1056/NEJMoa2306963 Ndumele CE, Neeland IJ, Tuttle KR, et al. A synopsis of the evidence for the science and clinical management of cardiovascular-kidney-metabolic (CKM) syndrome: a scientific statement from the American Heart Association. Circulation. 2023;148(20):1636-1664. doi:10.1161/CIR.0000000000001175 Khan SS, Matsushita K, Sang Y, et al. Development and validation of the American Heart Association’s PREVENT equations. Circulation. 2024;149(6):430-449. doi:10.1161/CIRCULATIONAHA.123.067626 Khan SS, Ning H, Shah SJ, et al. 10-year risk equations for incident heart failure in the general population. J Am Coll Cardiol. 2019;73(19):2388-2397. doi:10.1016/j.jacc.2019.02.057 Bozkurt B, Fonarow GC, Goldberg LR, et al. Cardiac rehabilitation for patients with heart failure: JACC expert panel. J Am Coll Cardiol. 2021;77(11):1454-1469. doi:10.1016/j.jacc.2021.01.030 Packer M. Leptin-aldosterone-neprilysin axis: identification of its distinctive role in the pathogenesis of the three phenotypes of heart failure in people with obesity. Circulation. 2018;137(15):1614-1631. doi:10.1161/CIRCULATIONAHA.117.032474 Lala A, Tayal U, Hamo CE, et al. Sex differences in heart failure. J Card Fail. 2022;28(3):477-498. doi:10.1016/j.cardfail.2021.10.006 Bozkurt B, Coats AJS, Tsutsui H, et al. Universal definition and classification of heart failure. Eur J Heart Fail. 2021;23(3):352-380. doi:10.1002/ejhf.2115 Hershberger RE, Givertz MM, Ho CY, et al. Genetic evaluation of cardiomyopathy—a Heart Failure Society of America practice guideline. J Card Fail. 2018;24(5):281-302. doi:10.1016/j.cardfail.2018.03.004 Levine GN, Cohen BE, Commodore-Mensah Y, et al. Psychological health, well-being, and the mind-heart-body connection: a scientific statement from the American Heart Association. Circulation. 2021;143(10):e763-e783. doi:10.1161/CIR.0000000000000947 Ezekowitz JA, Colin-Ramirez E, Ross H, et al. Reduction of dietary sodium to less than 100 mmol in heart failure (SODIUM-HF): an international, open-label, randomised, controlled trial. Lancet. 2022;399(10333):1391-1400. doi:10.1016/S0140-6736(22)00369-5

The Human Upgrade with Dave Asprey
The Foods, Drinks, and Daily Habits Wrecking Your Brain (Surprising!) | David Perlmutter : 1498

The Human Upgrade with Dave Asprey

Play Episode Listen Later Jul 9, 2026 53:04


Neurologist Dr. David Perlmutter Explains Brain Inflammation and Alzheimer's Risk Your brain has its own immune system, and when it turns against you, it becomes the hidden driver behind Alzheimer's, Parkinson's, depression, and even long COVID. This episode hands you the science to recognize it early and reverse it. Get Dr. Perlmutter's new book Brain Defenders: https://drperlmutter.com/books/brain-defenders/ Host Dave Asprey sits down with Dr. David Perlmutter, a board-certified neurologist and six-time New York Times bestselling author whose work sits at the intersection of neurology, nutrition, and brain health. He is a Fellow of the American College of Nutrition, serves on its Board of Directors, and sits on the Editorial Board of the Journal of Alzheimer's Disease. His books, including the number one bestseller Grain Brain, span 32 languages and have sold over a million copies, and his upcoming release, Brain Defenders, explores the pivotal role of microglia, the brain's immune cells, in protecting, repairing, and reprogramming the brain for lifelong resilience. Dave and Dr. Perlmutter break down how microglia, the brain's resident immune cells, shift from a supportive state into a destructive one called M1, and why this shift, not amyloid plaque, may be the real driver of Alzheimer's, Parkinson's, and other neurodegenerative conditions. They dig into why the leading amyloid-clearing drugs fail to improve cognition, what a landmark JAMA study revealed about reversing cognitive decline through lifestyle intervention alone, and why a single daily serving of ultra-processed food raised Alzheimer's risk by 13 percent in a 12.7 year study. They also cover new research on GLP-1 drugs and brain inflammation, the surprising role of gum disease and oral bacteria in dementia risk, and why 40 hertz light therapy is emerging as a low-cost tool for clearing brain plaque and calming neuroinflammation. You'll Learn: Why the shift from supportive to destructive brain immune cells may be the true root cause of Alzheimer's and Parkinson's Why leading Alzheimer's drugs fail to improve cognition, and what the original research behind the amyloid hypothesis actually showed How one daily serving of ultra-processed food raises Alzheimer's risk, and what a landmark lifestyle intervention study found instead Whether GLP-1 drugs help or harm brain inflammation, based on new Parkinson's and Alzheimer's trial data How gum disease and oral bacteria are linked to dementia, and simple daily habits that reduce that risk Why 40 hertz light therapy is emerging as a tool to clear brain plaque and calm neuroinflammation How ketones, DHA, and metabolic health protect the brain after head injury Thank you to our sponsors! - Beyond Wonderland Conference | Oct 13 - 14, 2026. Get your ticket now at wonderlandconference.com. - ZenBud | Dave's Nervous System Biohack. Visit zenbud.health and use code DAVE15 at checkout for a discount. - Pique | Head over to Piquelife.com/Dave to get 20% off your order. That's P-I-Q-U-E life dot com slash DAVE - PredictiveMind™ | Get your Brain Pattern Mapping report at predictivemind.io/dave and use code DAVE for 10% off. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: microglia, brain inflammation, Alzheimer's prevention, Parkinson's disease, amyloid hypothesis, neurodegeneration, GLP-1 drugs, semaglutide, ultra-processed food, gum disease and dementia, oral microbiome, 40 hertz light therapy, ketones, DHA, mitochondria, brain fog, long COVID, David Perlmutter, Brain Defenders, Grain Brain, functional medicine, biohacking, longevity, neuroplasticity Resources: • Get Dr. Perlmutter's New Book Brain Defenders: https://drperlmutter.com/books/brain-defenders/ • Learn More About Dr. Perlmutter's Work At: https://drperlmutter.com/ • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15? • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 00:40 – Intro 02:38 – Ultra-Processed Foods 06:34 – Are Carbs Bad? 08:48 – Alcohol & Brain Health 12:28 – Microglia & Inflammation 24:37 – Head Injury & Recovery 29:27 – Oral Bacteria & Dementia 34:08 – GLP-1s & Brain Inflammation 40:20 – 40 Hertz Light Therapy 48:35 – Air Pollution vs. Lead 50:27 – David's Closing Truth See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.