Podcasts about therapeutic use

Unlocked Patreon episode. Support Ordinary Unhappiness on Patreon to get access to all the exclusive episodes. patreon.com/OrdinaryUnhappinessIn the first installment of our two-part Thanksgiving Special, we discuss the so-called “Holiday Syndrome” in general and with an eye towards the upcoming US holiday season in particular. We explore how holidays catalyze some of our most elemental anxieties and fantasies as embodied in the institution known as the family. We walk through Sandor Ferenczi's “Sunday Neurosis,” the social injunction to indulge in “recreation,” and how that demand psychically re-creates the scene of the family in all its traumas, disappointments, and contingencies. Big helpings of regression, bottomless oral need, and displaced Oedipal antagonism are served – plus a reading of the traditional Thanksgiving meal itself, which not coincidentally features a lot of food that resembles what we feed babies. Subscribe now for immediate access to Part II - on Freudian anthropology, the history behind Thanksgiving, and the libidinal structures of settler colonialism. Subscription also will give you access to our ever-growing backlog of Patreon-only content, including series like The Standard Edition (we're reading Freud's complete works thing together!) Wild Analysis (psychoanalysis goes to the movies), Gerontophallocracy 2024 (on the recent election and beyond), and much, much more!Articles referenced include:Cattell, J P.  The Holiday Syndrome. The Psychoanalytic Review (1913-1957); New York Vol. 42, (Jan 1, 1955): 39, available here.Ferenczi, Sandor. Sunday Neuroses (1919) in Further Contributions to the Theory and Technique of Psycho-Analysis. London, Karnac Books 1927.Sarah Mullooly Sattin. The Psychodynamics of the “Holiday Syndrome”: The Meaning and Therapeutic Use of Holidays in Group Therapy with Schizophrenic Patients. Perspectives in Psychiatric Care. Volume 13, Issue 4 (October 1975), Pages 156-162, available here.Rosenbaum, J. B. (1962) Holiday, Symptom and Dream. Psychoanalytic Review 49, 87-98, available here.Melanie Wallendorf, Eric J. Arnould, “We Gather Together”: Consumption Rituals of Thanksgiving Day, Journal of Consumer Research, Volume 18, Issue 1, June 1991, Pages 13–31, available here. Have you noticed that Freud is back? Got questions about psychoanalysis? Or maybe you've traversed the fantasy and lived to tell the tale? Leave us a voicemail! (646) 450-0847  A podcast about psychoanalysis, politics, pop culture, and the ways we suffer now. New episodes on Saturdays. Follow us on social media:  Linktree: https://linktr.ee/OrdinaryUnhappiness Twitter: @UnhappinessPod Instagram: @OrdinaryUnhappiness Patreon: patreon.com/OrdinaryUnhappiness Theme song: Formal Chicken - Gnossienne No. 1 https://open.spotify.com/album/2MIIYnbyLqriV3vrpUTxxO Provided by Fruits Music

Today, we are exploring the benefits of Vitamin B6.Vitamin B6 is an essential nutrient for horses and humans, and I use it regularly for various purposes. In this episode, I explain how it functions in the body, the signs and causes of a Vitamin B6 deficiency, and how to use it effectively.Nutrient Deficiency and Therapeutic Use of B6 in HorsesVitamin B6 gets used for its therapeutic properties in horses, even without a confirmed deficiency. Many horses are likely deficient in Vitamin B6, especially those on hay diets without access to fresh forage.Regulatory Minimums in Horse FeedsIn Canada, the CFIA mandates minimum levels of fat-soluble vitamins (A, D, E) in horse feeds, but B vitamins like B6 are often left out. That can lead to deficiencies, as the commercial feeds might not always meet the nutrient requirements of some horses.Digestive and Absorption ChallengesMany horses struggle to absorb nutrients from their feed, especially those with digestive issues like ulcers, colic, or diarrhea. Even when given sufficient food, compromised digestion can reduce the effectiveness and compound nutritional deficiencies over time.Role of B6 in Metabolism and HealthVitamin B6 is essential for carbohydrate, protein, and fat metabolism, so it is critical for horses with metabolic conditions like insulin resistance. Vitamin B6 also supports magnesium and Vitamin B12 absorption and helps to address those nutrient deficiencies.B6 for Skin, Immunity, and InflammationVitamin B6 helps with conditions like itchy, flaky skin and hives in horses. It also improves immune health by regulating inflammation and fluid retention, making it particularly useful for horses with metabolic issues.Neurological and Behavioral BenefitsVitamin B6 is involved in neurotransmitter production, like serotonin and melatonin, which affect brain health and mood regulation. Horses with anxiety, depression, or behavioral issues may benefit from Vitamin B6 supplementation, as it helps balance the nervous system.Hormonal Imbalance and Liver SupportVitamin B6 helps regulate estrogen, making it useful for mares with hormonal issues or insulin-resistant horses with liver stress. It supports liver detoxification, which is crucial for horses with a high toxic load due to poor diet or metabolic conditions.Sources of B6Vitamin B6 is in flax and wheat germ, but it is hard to determine the exact amount in horse feed. As such, targeted Vitamin B6 supplementation is often necessary to meet their needs.Signs of Vitamin B6 DeficiencyDeficiency symptoms include hormonal imbalances, weight gain, joint inflammation (often misdiagnosed as arthritis), skin problems, depression, and anxiety. So, horses with these symptoms tend to improve with Vitamin B6 supplementation.Proper Dosage and FormsThe recommended Vitamin B6 dose for horses is around 750 mg of B6 daily, with up to 1000 mg for a loading dose. The pyridoxine form of B6 is commonly used for horses, while the P5P form is more bioavailable for humans.ConclusionVitamin B6 offers significant benefits, from supporting metabolic health to improving behavioral issues and reducing inflammation. If you are trying Vitamin B6 for your horse, pay attention to any health or mood changes and adjust the dosage as needed.Links and resources:Connect with Elisha Edwards on her website Join my email list to be notified about new podcast releases and upcoming webinars.Free Webinar Masterclass: Four Steps to Solving Equine Metabolic...

In this episode of the Ketamine Startup Podcast, we collaborate with Dr. Carl Bonnett, the founder of Klarisana and prior podcast guest, to explore the often misunderstood concept of ego death through the lens of Matthew Perry's experiences with ketamine therapy. The conversation also covers topics like the efficacy of ketamine in treating mental health conditions, near-death experiences induced by ketamine, and the crucial role of preparation and integration in ketamine therapy.Listen for a nuanced discussion that challenges preconceptions and sheds light on the therapeutic potential of ketamine when used responsibly. What You'll Learn in This Episode:• The Role of Media and Culture: How celebrity experiences can influence public interest and stigma surrounding psychedelic therapies.• Safety and Ethics in Ketamine Therapy: The importance of setting and professional oversight in ketamine treatments.• Personal Stories and Case Studies: Both Dr. Bonnett and Sam share anecdotes from their respective clinical practices, highlighting transformative experiences and common misconceptions.Episode 19 show notes:00:00 Episode Teaser - Ketamine & Near-Death Experiences00:23 Introduction00:31 Special Collaboration with Dr. Carl Bonnet01:52 Discussion on Matthew Perry and Ego Death02:36 Therapeutic Use of Ego Disruption05:39 Patient Experiences and Integration08:07 Safety and Responsible Use of Ketamine12:36 Education and Public Perception19:36 Concluding Thoughts and Final Remarks21:10 Additional Insights on Near-Death Experiences With SamThanks for listening - make sure to check out Dr. Bonnett's YouTube ChannelStudy mentioned in episode: Neurochemical models of near-death experiences: A large-scale study based on the semantic similarity of written reports. Martial C, et al. Learn more about the types of ketamine experiences: The 4 Types of Non-Ordinary Experiences Your Ketamine Patients Can HaveConnect with Dr. Bonnett at:Instagram: docbonnett_psychedelicLinkedIn: /carlbonnettYouTube: @docbonnett⭐️ Want to fast track launching your ketamine clinic? If so, download our free checklist

Hello listeners and welcome to a new format of episode! In these episodes Jenna and John will unpack some of their history with the genre of horror and how their love for these movies has evolved over time. Join us for this week's episode as we discuss the kids movies that scared us half to death when we were young, and still stick with us to this day!

In this episode of the "Vibe Science" podcast, hosts Ryan Alford and Chris Hanson interview Paul Austin, founder of Third Wave, about the evolving perceptions and therapeutic potential of psychedelics, with a focus on microdosing. Paul shares his personal journey and insights into the history and current landscape of psychedelics, discussing their medical applications and the societal stigma surrounding them. The conversation touches on recent legalization efforts, the impact of COVID-19 on mental health and psychedelic use, and the promising future of psychedelics in mental health treatment. Ryan and Chris emphasize the importance of open discussions about these substances.TAKEAWAYSEvolving perceptions of psychedelics and microdosingTherapeutic benefits of psychedelics for mental healthPersonal journeys and experiences with psychedelicsSocietal stigma surrounding psychedelic useRecent legalization efforts for psychedelics in various statesImpact of COVID-19 on mental health and psychedelic useHistorical context and evolution of psychedelic useImportance of safe and regulated therapeutic settingsMicrodosing as an accessible entry point for new usersFuture potential of psychedelics in mental health treatmentTIMESTAMPSIntroduction to Vibe Science (00:00:00)Introduction of the podcast, hosts Ryan Alford and Chris Hanson.Welcoming Paul Austin (00:00:36)Hosts welcome guest Paul Austin, founder of Third Wave, discussing his influence in the psychedelic space.Stigmatization of Psychedelics (00:01:35)Ryan shares his evolving views on psychedelics and their potential therapeutic benefits.Legalization Efforts (00:02:25)Paul discusses recent legalization of psilocybin mushrooms in Colorado and Oregon, and decriminalization in several cities.Historical Context of Psychedelics (00:05:13)Paul reflects on his journey with psychedelics and their historical use in society.The Third Wave Concept (00:06:14)Paul explains the concept of Third Wave, integrating ancient and modern perspectives on psychedelics.Psychedelics vs. Traditional Drugs (00:14:36)Discussion on the safety and potential of psychedelics compared to traditional substances like alcohol and tobacco.Cultural Shifts and Milestones (00:16:56)Paul outlines key milestones in the psychedelic movement, including Michael Pollan's influential book.Impact of COVID-19 (00:18:59)The pandemic increased psychedelic use and interest in mental health treatments, including ketamine therapy.Future of Psychedelics (00:20:05)Paul predicts widespread legal access to psychedelics in the coming years, driven by public support and clinical research.Personal Journey with Psychedelics (00:22:20)Paul shares his personal experience with psychedelics and their impact on processing emotions.Advocacy for Psychedelics (00:23:20)Paul discusses his strong belief in psychedelics as powerful tools for emotional and spiritual healing.Understanding Different Substances (00:24:26)Paul explains the various psychedelics and their distinct experiences, emphasizing the importance of substance choice.Therapeutic Use of Ketamine (00:27:19)The therapeutic applications of ketamine are discussed, including its benefits for depression and suicidality.Risks of Ketamine Use (00:28:36)Paul highlights the dangers of unsupervised ketamine use and the importance of a safe therapeutic setting.Microdosing Benefits (00:29:57)Microdosing benefits are outlined, focusing on improved mood, energy, and sleep without significant intoxication.Ketamine Therapy Experience (00:30:30)Discussion on whether patients talk during ketamine therapy sessions, depending on the dosage used.Navigating Emotional Release (00:32:29)The conversation addresses the balance between emotional vulnerability and resilience, especially for men.Mindset and Psychedelics (00:34:02)Paul emphasizes the importance of mindset when using psychedelics for personal development and resilience.Personal Development vs. Recreational Use (00:36:30)The distinction between using psychedelics for personal growth versus recreational enjoyment is explored.Self-Regulation and Responsibility (00:38:32)The need for self-regulation in substance use is discussed to avoid dependency.Starting with Psychedelics (00:39:58)Paul advises beginners on how to approach psychedelics safely and responsibly, starting with microdosing.Credibility in Psychedelic Discussions (00:42:01)Ryan praises Paul for his in-depth knowledge and credible approach to discussing psychedelics.Resources for Learning More (00:42:56)Paul shares where listeners can find more information about psychedelics and microdosing through Third Wave.Personal Contact Information (00:43:17)Paul shares his social media handles for listeners to reach out with questions.Appreciation and Credibility (00:43:30)Ryan expresses gratitude for Paul's insights and credibility during the episode.Acknowledgment of Hosts (00:43:37)Paul thanks Ryan and Chris for their contributions and sharing their stories.Excitement for Episode Release (00:43:44)Chris shares his enthusiasm for the episode's release and its potential impact on listeners.Episode Summary and Resources (00:43:51)Ryan provides information on where to find episode highlights, full episodes, and guest resources.Medical Disclaimer (00:44:04)Ryan emphasizes that the content is for educational purposes and not medical advice.Closing Remarks (00:44:12)Ryan thanks listeners and encourages them to visit the podcast website for more information. Follow us on Instagram: @Vibe.Science Subscribe to our YouTube Page: www.youtube.com/@Vibe.Science

Kerri Fox, Executive Director and CEO of Resounding Joy, discusses her organization's dedication to transforming lives through the healing power of music therapy.  Fox chats about the clients they serve.

Angela Ardolino has over 20 years of experience in holistic pet health, earning her stripes as a certified holistic pet health coach, certified cannabis & fungi expert, and animal advocate. With a fervent dedication to educating and empowering pet parents, Angela champions the use of whole plant and mushroom medicine to support our pets' best health.As a graduate of the inaugural class of Medical Cannabis for Therapeutic Use at the University of Vermont. She has been a member of the The Society of Cannabis Clinicians since 2017, as well as a vocal supporter of safe, natural, and ethically-grown whole plant and fungi medicine for pets.In addition to her public engagements, Angela hosts the acclaimed podcast Your Natural Dog with Angela Ardolino, where she delves into holistic pet care topics with industry experts. From nutrition to natural remedies and behavior to training, Angela empowers pet parents with informed decision-making for their pets' well-being.Angela's journey into whole plant and fungi medicine was sparked by her success in using cannabis to treat her own rheumatoid arthritis. Recognizing the need for safe, effective full-spectrum hemp extract CBD tailored for dogs, she founded CBD Dog Health in 2018. Angela's line of CBD products for pets are formulated using high quality ingredients grown in the U.S., and specifically formulated for animals, prioritizing pet safety and efficacy.Driven by her own dogs' health challenges, including her beloved doberman Nina's battle with osteosarcoma and her senior schnauzer Odie's aging-related issues, Angela tackled medicinal mushrooms for dogs next. Teaming up with mycologist and spagyricist Jason Scott, she created MycoDog, a line of sustainable mushroom extract and adaptogen tinctures, triple extracted from the fruiting bodies of mushrooms, wild-harvested in the U.S.Keywords:Mushrooms| Fungi| Health| Functional Health| Medicinal| Medicine| Podcast| China| Dogs| Cannabis| CBD| Substrate Matters| Flora Funga Podcast|Resources:AngelaArdolino.comYourZbiotics: "FLORA10"Drink ZBiotics before drinking alcohol-Alcohol produces acetaldehyde, a byproduct that your next daySupport the Show.***I am an affiliate with ENERGYBITS (your daily algae tablet packed with nutrients) go visit this link and use code FLORAFUNGA at checkout for 20% off***Get 20% off Sovereignty use code "KK20" Zbiotics: "FLORA10"Drink ZBiotics before drinking alcohol-Alcohol produces acetaldehyde, a byproduct that your next day SUPPORT THE SHOW: Join my Patreon for only $1/month [THATS only .03 cents a day!]Follow my other social media sites to interact and engage with me:Email me to be on the podcast or inperson Interview: floraandfungapodcast@gmail.com FacebookInstagramTwitterTikTokYouTubePatreonNew audio done by Reflect--go show him some support!-Spotify...

View the Show Notes For This Episode Dr. Howard Elkin and Dr. Ben Weitz defend the Therapeutic Use of Niacin. [If you enjoy this podcast, please give us a rating and review on Apple Podcasts, so more people will find The Rational Wellness Podcast. Also check out the video version on my WeitzChiro YouTube page.]   Podcast Highlights     Dr. Howard Elkin is an Integrative Cardiologist with offices in Whittier and in Santa Monica, California and he has been in practice since 1986.  While Dr. Elkin does utilize medications and he performs angioplasty and stent placement and other surgical procedures, his focus in his practice is employing natural strategies for helping patients, including recommendations for diet, lifestyle changes, and targeted nutritional supplements to improve their condition.  Dr. Elkin has written an excellent new book, From Both Sides of the Table: When Doctor Becomes Patient.  His website is Heartwise.com and his office number is 562-945-3753. Dr. Ben Weitz is available for Functional Nutrition consultations specializing in Functional Gastrointestinal Disorders like IBS/SIBO and Reflux and also Cardiometabolic Risk Factors like elevated lipids, high blood sugar, and high blood pressure.  Dr. Weitz has also successfully helped many patients with managing their weight and improving their athletic performance, as well as sports chiropractic work by calling his Santa Monica office 310-395-3111.  

Get ready for a journey that takes you beyond the pain of heartbreak and into a world where loss transforms into growth with science journalist Florence Williams, who shares her personal triumph over the heartbreak of divorce, which inspired her to write a book on the subject. This episode sheds light on how heartbreak reshapes our bodies and minds. You'll gain valuable tactics for emotional healing, understand the crucial role of touch in regaining trust, and see how therapeutic practices like EMDR and rituals can offer relief. For those on the mend or helping others heal, this discussion is packed with practical advice to help you transform the trials of heartbreak into a journey of empowerment. This episode provides clear steps to recover and emerge stronger from life's emotional challenges. Timestamp Highlights (00:02:26) Florence Williams' Journey Through Divorce (00:07:42) Divorce as a Story of Inflammation (00:13:43) Rebuilding Connection Post-Heartbreak (00:18:02) Embracing Beauty and Awe in Healing (00:23:22) Therapeutic Use of Psychedelics in Overcoming Heartbreak (00:34:33) Reestablishing Trust After Betrayal (00:38:04) The Healing Power of Touch and Oxytocin (00:44:51) Safe Relationships and Self-Discovery Post-Divorce (00:50:33) Journaling as a Tool for Processing Emotions Sponsors ARMRA | Go to https://www.TryARMRA.com and use code Dave for 15% off BEAM Minerals | Go to www.Beam Minerals.com/Dave2024 for 20% off your first order. Resources Get your copy of ‘Heartbreak' by Florence Williams: https://www.florencewilliams.com/books-2 Florence Williams website: https://www.florencewilliams.com/ Follow Florence Williams: @Florence999 Dave Asprey's Book ‘Smarter Not Harder' is out now: https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Follow The Human Upgrade: @TheHumanUpgradePodcast See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Join Craig and Ivan Soto on The Bad Roman Podcast as they explore the connection between Christianity, anarchy, and psychedelics. In this episode, Ivan discusses his transformative experiences with these substances and their significant impact on his spiritual journey. The conversation tackles the government's control over these plants, their historical ties to witchcraft, and the need for open discussions within the Christian community about the potential therapeutic and spiritual benefits of psychedelics. Don't miss this insightful episode as we delve into the potential of psychedelics as a valid path to the divine and challenge traditional sources of spiritual knowledge. SUPPORT THE PROJECT: thebadroman.com/donate Connect with Ivan: Facebook Instagram Starting Points & Key Moments: 01:02 Introduction: Exploring Psychedelics and Christianity 02:00 The Double-Edged Sword of Psychedelics 06:00 Stigmas Surrounding Psychedelics 09:16 Exploring Psychedelics and Spirituality 11:00 Government Regulations and Psychedelics 12:00 The Christian Perspective on Psychedelics 13:01 Debunking Misconceptions About Witchcraft 17:00 Psychedelics as Tools for Spiritual Insight 20:00 The Cultural Significance of Psychedelics 22:54 The Therapeutic Potential of Psychedelics 27:45 Importance of Set and Setting in Psychedelic Use 30:00 Using Psychedelics for Personal Growth 32:26 The Dark Side of Psychedelics: Bad Trips 34:00 Recreational vs Therapeutic Use of Psychedelics 35:00 Psychedelics for Depression and Grief 35:09 Spiritual Enlightenment: Scripture vs Psychedelics 40:00 The Role of the Holy Spirit in Guiding Truth 43:00 Beyond the Bible: Other Sources of Divine Inspiration For Full Show Notes: https://www.thebadroman.com/show-notes/episode-107   For more on The Bad Roman Project: Blog submissions: thebadroman.com/contribute-to-the-blog Connect with us on social: thebadroman.com/social-links Want to get more involved? Request to join the private discussion group on Facebook (Bad Romans Only!!) No King but Christ Network: nokingbutchristnetwork.com  

In today's episode, I answer a question from Summer in Illinois.  She asked about the use of board games in the playroom. As a tool in child-centered play therapy, board games serve as a conduit for emotional growth, problem-solving, and social interaction. This episode's content highlights how the structured nature of board games can be leveraged to foster meaningful therapeutic outcomes. I also go over the most common questions I get about board games in the playroom, such as cheating, power and control, and how it applies to my concept of the "power pendulum."   If you would like to ask me questions directly, check out www.ccptcollective.com, where I host two weekly Zoom calls filled with advanced CCPT case studies and session reviews, as well as member Q&A.  You can take advantage of the two-week free trial to see if the CCPT Collective is right for you.   Ask Me Questions:  Call ‪(813) 812-5525‬, or email: brenna@thekidcounselor.com Brenna's CCPT Hub: https://www.playtherapynow.com CCPT Collective (online community exclusively for CCPTs): https://ccptcollective.com Podcast HQ: https://www.playtherapypodcast.com APT Approved Play Therapy CE courses: https://childcenteredtraining.com Twitter: @thekidcounselor   https://twitter.com/thekidcounselor Facebook: https://facebook.com/playtherapypodcast   References: Cochran, N., Nordling, W., & Cochran, J. (2010). Child-Centered Play Therapy (1st ed.). Wiley. VanFleet, R., Sywulak, A. E., & Sniscak, C. C. (2010). Child-centered play therapy. Guilford Press. Landreth, G. L. (2002). Play therapy: The art of the relationship (2nd ed.). Brunner-Routledge. Bratton, S. C., Landreth, G. L., Kellam, T., & Blackard, S. R. (2006). Child parent relationship therapy (CPRT) treatment manual: A 10-session filial therapy model for training parents. Routledge/Taylor & Francis Group. Benedict, Helen. Themes in Play Therapy. Used with permission to Heartland Play Therapy Institute.

In this episode, we have a fantastic conversation with Angela Ardolino who specializes in holistic health for both animals & people with a strong focus in cannabis & medicinal mushrooms. As an advocate of the power of whole plant medicine, Angela leads this informative conversation as we explore misconceptions, challenges, benefits, and everything in between regarding cannabis, mushrooms, and the healthcare system. Angela is currently on the Healing Pets Naturally Tour with Dr. Judy Morgan and joining the Forever Dog Book and the Modern Pet Parent Book tours in 2024.   About Angela: Angela is a certified holistic pet health coach and a certified cannabis/fungi clinician expert. She spends much of her time creating personalized formulations for individual animals and humans alike, teaching and sharing her extensive knowledge, and hosting It's a Dog's Life podcast on Cannabis Radio & Your Natural Dog podcast on YouTube. Angela's mission is to educate and empower pet parents to heal and support their pets using whole plant and mushroom medicine. She is also a vocal advocate for safe and natural hemp and cannabis use for both humans and animals. She attended the University of Vermont's inaugural class in Medical Cannabis for Therapeutic Use and used her expertise to found CBD Dog Health, which offers all-natural, full-spectrum hemp products for pets suffering from various conditions, as well as to launch MycoDog, a line of sustainable mushroom extract and adaptogen tinctures for dogs which was inspired by her own dog's experience with cancer. Angela shares her knowledge through her podcast, Your Natural Dog, and has been featured on various holistic pet health and wellness podcasts.    Where to find Angela: Website: www.angelaardolino.com Social Media: @angelaardolino, @cbddoghealth, @yournaturaldog, @mushroomsfordogs Podcast: Your Natural Dog - https://podcasts.apple.com/us/podcast/your-natural-dog-with-angela-ardolino-formerly-its/id1596801011   Other Resources:  CBD Resource website: www.projectcbd.org Netflix Documentary: Fantastic Fungi   -------------------------------------------------   Disclaimer: The views and opinions shared by The Animal Files Podcast hosts are based on their experiences and education. The views shared by TAF's guests do not necessarily reflect that of the hosts. We always recommend that our listeners consult animal industry professionals when necessary and are not responsible for any losses, damages, or liabilities that may arise from the use of the information in this podcast.   Be sure to follow The Animal Files online and on Facebook! www.theanimalfilespodcast.com www.facebook.com/theanimalfilesofficial Instagram => @theanimalfileofficial   Have a topic you would like us to tackle?  Email us at: theanimalfilespodcast@gmail.com   Want to support the show? => Become a Patron: www.patreon.com/theanimalfilesofficial Or grab some Merch: http://www.teepublic.com/user/positivitees/albums/129886-the-animal-files-podcast-and-radio-show   Don't forget to Rate, Review, Follow, and Subscribe on all of your favorite podcasting platforms!  

Today, Amy Keith, DoTerra Wellness Advocate, joins me on the podcast and we have a wonderful conversation about all things essential oils. Amy is a teacher who has found a passion for not only teaching kids in the daytime, but also educating adults about how to use essential oils to support their health and daily wellness. From the very first conversation I had with Amy about essential oils, her passion it was clear to me, and that she was the perfect person to help break down the foundational information around understanding essential oils.  I would imagine you have heard about oils and likely even used them at this point, but, if you are like me, you are iffy on how to use them more than just sporadically in my diffuser.  Amy tells us all the ways to use them safely and does a phenomenal explaining the importance of understanding where your oils have come from and why you need to use quality oils. She shares about how, in her own life, she has moved to using her oils preventively to help support her stress levels and health. I have been inspired to use my oils more in my daily life as well after this awesome conversation. As you listen, I hope you are inspired to learn more about how to use oils in your own life. Amy reminds us that its just start with understanding just one oil, getting comfortable with that, and then adding another. Please like and share this episode with your friends and let's help spread awareness about this incredible way to naturally support your body and health. Remember, it's ok to not be ok, but let's not stay there.  Resources Mentioned: Book:  Modern Essential Handbook: The Premier Introductory Guide to the Therapeutic Use of Essential OilsWebsites: AromaTools - Essential Oil Tools & AccessoriesOil Magic BookdoTERRA eBooks—Archive | doTERRA Essential OilsWays to Find Amy:Email: amy.keith@sbcglobal.netInstagram: Amy Keith (@wellness.is.worth.it) • Instagram photos and videosWays to Find Embrace. Live. Thrive.:Website: Embrace, Live, Thrive! (embracelivethrive.com)Instagram: Sarah Meyer (@embracelivethrive) • Instagram photos and videosFacebook: Embrace, Live, Thrive | O'Fallon MO | FacebookAmy Bio: Welcome, friend! I'm so glad you are here! Although I don't know enough about technology to be doing this, here I am! My hope is that I can help you find natural solutions to your health and wellness issues! Wellness is a journey, and I can promise, it is worth it! My husband and I have been married for 37 years and we have two beautiful kids, both grown and married! Our labradoodle, Sophie, is a fully trained therapy dog and is about to retire along aside myself in just a couple of months from teaching reading to special needs kiddos. I love nature, gardening, reading, my family, and learning and teaching about DoTerra essential oils and everything wellness.

In this episode, Jay interviews Megan and Nicole Michelena, a pair of certified microdosing coaches who founded a holistic wellness and mentorship firm called Zenchronicity. Their mission is to empower people to take back their power, grace, and create their own reality by leveraging neuroplasticity. The conversation centers around the transformative power of psychedelics, especially psilocybin and its potential for healing and personal growth. They also discuss how societal conditioning has suppressed the divine feminine and emphasize the need for everyone to restore balance between masculine and feminine energies. Tune in if you've been curious about psychedelics, or if you're looking for advice on how to maintain mindfulness and self-awareness in a world full of toxicity and temptation. This conversation with the world's foremost “microdosing mentors” is sure to help you reconnect with your spiritual essence. “To create and to nurture is masculine. To flow, to manifest, to understand divine essence is feminine. When you balance your masculine and feminine, you literally become unstoppable.” – Megan Michelena   What You'll Learn From This Episode Psilocybin and Healing - How certain strains can target specific energy centers in the body and help address trauma and promote healing. Divine Feminine and Masculine Energies - The danger of women being objectified and men lacking purpose, and why we must rebalance masculine and feminine energy.   Awakening and Breaking the Matrix - The role of inner work, psychedelics, and guided spiritual experiences in breaking free from societal programming and truly awakening. Surrender and Plant Medicine - Personal experiences of surrendering to the medicine and accessing higher states of consciousness, including profound healing and connection. Dark Forces and Energy Harvesting - How to shield yourself from dark entities that feed off negative energy and create a continuous frequency of fear and anxiety throughout society.    Key Moments In This Conversation 00:00:00 - Introduction 00:03:29 - The Power of Psilocybin and Other Psychedelics 00:11:35 - The Impact of Modern Society on Mental Health 00:13:17 - The Role of Psychedelics in Healing and Neuroplasticity 00:37:25 - The Power of Ayahuasca and Other Plant Medicines 00:40:31 - The Importance of Balancing Masculine and Feminine Energies 00:47:32 - The Energetic Dangers of Electromagnetic Frequencies 00:52:35 - Dark Entities and Their Impact On Society 01:05:07 - The Decriminalization and Therapeutic Use of Psilocybin 01:12:49 - Closing Thoughts & Guest Resources Guest Bio Megan and Nicole Michelena are sisters who have founded a microdose mentorship program called Zenchronicity focused on healing through psilocybin. Their practice focuses on helping clients address trauma, take back their power, and manifest their future by leveraging neuroplasticity to help them create new pathways. Megan and Nicole are experts in the areas of energetic fields, psychedelics, and plant-based medicine and they have hundreds of hours of practical experience working with clients through individual coaching, group mentorship, or guided spiritual experiences. Learn more about the “Zenchronicity Sisters” and their work at www.zenchronicity222.com.   Jay Campbell Products & Resources

In this weeks Cannabis News and Events we cover the following stories |  Dogs Given CBD See 'Significant Reductions' In Stress And Anxiety Related To Riding In Cars, Study Finds New York Officials Will Vote On Marijuana Home Cultivation Rules This Week Woman avoids jail for fatally stabbing man over 100 times during cannabis psychosis Albanian man who came to UK on small boat jailed for producing cannabis in Ashington New Hawaii Bill Would Create A Limited Therapeutic Psilocybin … Israel opens "anti-dumping" investigation into cannabis imports Come and join in the discussion about any of these news articles on our cannabis growing forum, Discord server, or any of your favourite social networks. Visit our website for links.  Website: https://highonhomegrown.com Discord: https://discord.gg/sqYGkF4xyQ Youtube: https://www.youtube.com/highonhomegrown Thank you for downloading and listening to our cannabis podcast! I hope you enjoy this episode.

This episode continues our "Sober Curious" conversation from Episode 88, diving deeper into community stories and examining the roles of cannabis and psilocybin and being "California Sober". We also explore the question, "What is a substance?"You'll hear from community members about their evolving relationships with substances, the impact these substances have on personal relationships and mental health, and diverse perspectives on defining a substance.Please note: If discussions about substance abuse and/or sexual assault are triggering for you, we recommend skipping this episode.Get the Sober Curious Support GuideWhat should we talk about next?Substance definitionEpisodes Referenced:Ep 88- Sober Curious Part 1Ep 5- Microdosing and Earth MedicineEp 83- The History of MushroomsSupport the showFollow @howthewiseonegrows and @hollyzajur on Instagram for more and check out more offerings online.Join the ~*Dream Team*~ and get a shout-out on our next episode as you help make dreams come true!Episode sponsored by Connect Wellness. Connect Wellness empowers people with tools to connect with themselves, others, and the present moment.Be wise-- sign up to be the first to know what's next!

Autistic and other neurodivergent people of all ages are vulnerable to many factors, both internal and external, that may lead to anxiety and phobias. Dr. Karen Levine's publications and clinical innovations have directly addressed these challenges in respectful and insightful ways. We discuss ways to understand such challenges and provide support based on a deeper understanding of the experiences shared by autistic individuals and neurodivergent individuals. Karen discusses her approach focusing on relationships, affective support, and the use of humor in co-regulation . Explore more on the episode's webpage. 

Subscribe to get access to the full episode, the episode reading list, and all premium episodes! www.patreon.com/OrdinaryUnhappinessIn the first installment of our two-part Thanksgiving Special, we discuss the so-called “Holiday Syndrome” in general and with an eye towards the upcoming US holiday season in particular. We explore how holidays catalyze some of our most elemental anxieties and fantasies as embodied in the institution known as the family. We walk through Sandor Ferenczi's “Sunday Neurosis,” the social injunction to indulge in “recreation,” and how that demand psychically re-creates the scene of the family in all its traumas, disappointments, and contingencies. Big helpings of regression, bottomless oral need, and displaced Oedipal antagonism are served – plus a reading of the traditional Thanksgiving meal itself, which not coincidentally features a lot of food that resembles what we feed babies.The second part of our Thanksgiving Special – on Freudian anthropology, the history behind (and of) Thanksgiving, and the libidinal structures of settler colonialism – drops Wednesday, Nov 22, just in time for your holiday travel.Articles referenced include:Cattell, J P.  The Holiday Syndrome. The Psychoanalytic Review (1913-1957); New York Vol. 42, (Jan 1, 1955): 39, available here.Ferenczi, Sandor. Sunday Neuroses (1919) in Further Contributions to the Theory and Technique of Psycho-Analysis. London, Karnac Books 1927.Sarah Mullooly Sattin. The Psychodynamics of the “Holiday Syndrome”: The Meaning and Therapeutic Use of Holidays in Group Therapy with Schizophrenic Patients. Perspectives in Psychiatric Care. Volume 13, Issue 4 (October 1975), Pages 156-162, available here.Rosenbaum, J. B. (1962) Holiday, Symptom and Dream. Psychoanalytic Review 49, 87-98, available here.Melanie Wallendorf, Eric J. Arnould, “We Gather Together”: Consumption Rituals of Thanksgiving Day, Journal of Consumer Research, Volume 18, Issue 1, June 1991, Pages 13–31, available here.Have you noticed that Freud is back? Got questions about psychoanalysis? Or maybe you've traversed the fantasy and lived to tell the tale? Leave us a voicemail! 484 775-0107 A podcast about psychoanalysis, politics, pop culture, and the ways we suffer now. New episodes on Saturdays. Follow us on social media: Linktree: https://linktr.ee/OrdinaryUnhappiness Twitter: @UnhappinessPod Instagram: @OrdinaryUnhappiness Patreon: patreon.com/OrdinaryUnhappiness Theme song: Formal Chicken - Gnossienne No. 1 https://open.spotify.com/album/2MIIYnbyLqriV3vrpUTxxO Provided by Fruits Music

Amber and Marcus Capone are a power couple dedicated to helping veterans and their families overcome trauma and find healing. Marcus is a former Navy SEAL with over 20 years of military service, and Amber is a passionate advocate for mental health and wellness. Together, they founded VETS, an organization that provides psychedelic therapy and support for veterans struggling with mental health issues.In this episode of Behind The Seen, Amber and Marcus Capone share their journey of overcoming trauma and finding healing through psychedelic therapy. They discuss the challenges they faced in their relationship and the impact of Marcus's military service on his mental health. They explain how they discovered the potential benefits of psychedelics for treating trauma and the transformative effects it had on Marcus's well-being. The couple also discusses the importance of community support and the need for more research and access to psychedelic therapy for veterans.KEY TAKEAWAYSPsychedelic therapy can be a powerful tool for healing trauma and improving mental health.The default mode network in the brain, which is associated with the ego and self-identity, can be quieted by psychedelics, allowing for new perspectives and healing.Psychedelic therapy should be done under the guidance of trained professionals and with proper integration and support.Veterans and their families can benefit from community support and access to alternative therapies like psychedelics.More research and funding are needed to expand access to psychedelic therapy for veterans and improve mental health care.HIGHLIGHT QUOTES"Psychedelics are medicines that were abused as recreational drugs, not recreational drugs turned into medicine." - Amber Capone"Psychedelics get to the root cause of the issue and help establish new neuronal connections in the brain." - Marcus Capone"Psychedelics are a tool, not a magic bullet. They require proper guidance, integration, and therapy for optimal results." - Amber Capone"We have to leave the country to get meaningful solutions to healthcare. It's horribly embarrassing." - Amber Capone"The more we can serve and help others, the more things happen in our own lives." - Marcus CaponeConnect and Learn more about Marcus and Amber.Marcus' LinkedIn Profile: https://www.linkedin.com/in/marcuscapone/Amber's LinkedIn Profile: https://www.linkedin.com/in/amber-capone/TARA Mind Website: https://taramind.com/VET Solutions Website: https://vetsolutions.org/Connect and learn more about Dean Stott.Instagram: @deanstottLinkedIn: https://www.linkedin.com/in/dean-stott-24725880Website: https://www.deanstott.com/about-deanConnect and learn more about Alana Stott.Instagram:@alanastottLinkedIn: https://www.linkedin.com/in/alana-stott-mbe-194493aaWebsite: https://alanastott.com/

Guest: Karen McWaters, MOT, OTR/L - With all the therapy tools we have access to, all the worksheets, toys, and bubbles, it is important to understand that you are your own best tool. Karen and Erin discuss the role of effect and attunement to truly connect with children and their caregivers in sessions. They discuss the intentional relationship model and how we clinicians can use it to truly identify and improve our relationships with our clients and their caregivers to further build our connection. They will discuss the evidence behind relationship-based therapy and the true heart and joy that comes with it.

In this episode we are talking all about therapeutic use of self with psychotherapist, academic, author, researcher and former occupational therapist, Linda Finlay. We discuss:  Linda is an integrative psychotherapist who has her own private practice in the UK.  Linda originally qualified as an occupational therapist in 1977 and worked in the mental health field in … 107 – Therapeutic Use of Self: Personal & Professional Self Intertwined ft Linda Finlay Read More »

In this episode we are talking all about therapeutic use of self with psychotherapist, academic, author, researcher and former occupational therapist, Linda Finlay. We discuss:  Linda is an integrative psychotherapist who has her own private practice in the UK.  Linda originally qualified as an occupational therapist in 1977 and worked in the mental health field in … 107 – Therapeutic Use of Self: Personal & Professional Self Intertwined ft Linda Finlay Read More »

In this week's guest interview, Jess & Rye are having an enlightening conversation with Microdosing and Plant Medicine Mentor, Tiffany Hurd!  In this episode, we discuss:  -Microdosing 101: what is it, who it might be for and transformations one may experience -Difference between psilocybin “magic” and functional mushrooms  -Legalities around psilocybin and how to safely find the right dosage and medicine for you -How Tiffany supports her clients in weaning off depression and anxiety medication and replacing it with microdosing + her own story using plant medicine to heal past trauma and depression and come off pharmaceuticals -Microdosing as a skill that can be improved and refined for use in personal growth and healing, anxiety, depression and PTSD -The difference between recreational and therapeutic use and how to figure how what's best for you  -Ways to work with Tiffany 1:1 as your guide + learn more about mushroom ceremonies  -&& more!! RESOURCES:  - Download Tiffany's free macrodosing guide HERE CONNECT WITH TIFFANY  Instagram @iamtiffanyhurd Website: https://tiffanyhurd.com Book a microdosing intro call HERE CONNECT WITH RYE+JESS Email: solo2.0podcast@gmail.com Instagram ⁠⁠⁠@solo2.0podcast⁠⁠⁠ Follow Jess ⁠⁠⁠@bodyblissbyjess⁠⁠⁠ Follow Rye ⁠⁠⁠@ryeburch⁠⁠ Follow Your Hormone Balance ⁠⁠@yourhormonebalance

Use of diabetes medications in non-approved (aka off-label) ways is increasingly common. This month, Amy and Liz dig into common off-label usage of Type 2 medications in insulin-deficient diabetes. Meds like GLP-1s, SLGT2's, and metformin have an established history as a treatment for improving insulin sensitivity in T1's. Ever wonder how that works and what the potential down sides are? While they're on the topic of medications used for non-FDA-approved purposes, stay for the second half of the episode where they delve into use of supplements (cinnamon and turmeric) for diabetes management and if/how it works (the answer may surprise you) (or not).Instagram @diacastpodcast (https://www.instagram.com/diacastpodcast/)Facebook Diacast (https://www.facebook.com/diacastpodcast)Email us at contact@diacast.comPlease feel free to join the wonderful diabetes communities on Reddit and Discord.r/diabetes subreddit:https://www.reddit.com/r/diabetes/r/Diabetes discord:discord.gg/diabetesPatreon (help us stop losing money - plus early access, bloopers, and more!)https://patreon.com/diacastReference Linkshttps://diatribe.org/how-people-diabetes-are-getting-during-ozempic-shortageOff-Label Medication in T1D https://www.utsouthwestern.edu/newsroom/articles/year-2023/february-type-1-diabetes.htmlGLP-1s in T1D https://www.endocrinologyadvisor.com/home/topics/diabetes/type-1-diabetes/type-1-diabetes-adjunct-insulin-therapy-glucagon-like-peptide-1-receptor-agonists-glp-1-ra/Current and Therapeutic Use of Metformin https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915435/Metformin in T1D [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771191/#:~:text=Metformin reduces hepatic glucose production,20%2C 21%2C 26]](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771191/#:~:text=Metformin reduces hepatic glucose production,20%2C 21%2C 26])https://www.sciencedirect.com/science/article/pii/S2589936821000049Metformin as an anti-cancer med https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497052/#:~:text=Based on recent analyses and,prostate%2C colon%2C pancreas%2C andTZDs in Diabetic Children and Beta Cell Preservation https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890222/TZDs Info https://dtc.ucsf.edu/types-of-diabetes/type2/treatment-of-type-2-diabetes/medications-and-therapies/type-2-non-insulin-therapies/insulin-sensitizers/TZDs in T2 Treatment

Rewiring Your Core Wound Patterns September 2023 http://jjflizanes.com/rewire   VIP Day with JJ for an Emotional Breakthrough http://jjflizanes.com/VIP   Dr. Nasha Winters is a sought-after luminary and global healthcare authority in integrative cancer research. She consults with physicians around the world bridging ancient therapies with advancements in modern medicine in the digital era. A personal journey with cancer and a medical career spanning over 25 years has Dr. Nasha on a mission to educate and empower the nearly fifty percent of the population expected to have cancer in their lifetime.   JJ Flizanes is an Empowerment Strategist and the host of several podcasts including People's Choice Awards nominee Spirit, Purpose & Energy. JJ Flizanes works with conscious, spiritual truth seekers who want to remove emotional blocks to success. She helps people identify sabotaging patterns and transmute struggle into joy. Through a series of clarifying exercises, she is able to curate a personalized roadmap to emotional healing.  JJ is passionate about empowering people with the knowledge and awareness of how they can live the life of their dreams. http://jjflizanes.com    

Rewiring Your Core Wound Patterns September 2023 http://jjflizanes.com/rewire   VIP Day with JJ for an Emotional Breakthrough http://jjflizanes.com/VIP   Dr. Nasha Winters is a sought-after luminary and global healthcare authority in integrative cancer research. She consults with physicians around the world bridging ancient therapies with advancements in modern medicine in the digital era. A personal journey with cancer and a medical career spanning over 25 years has Dr. Nasha on a mission to educate and empower the nearly fifty percent of the population expected to have cancer in their lifetime.   JJ Flizanes is an Empowerment Strategist and the host of several podcasts including People's Choice Awards nominee Spirit, Purpose & Energy. JJ Flizanes works with conscious, spiritual truth seekers who want to remove emotional blocks to success. She helps people identify sabotaging patterns and transmute struggle into joy. Through a series of clarifying exercises, she is able to curate a personalized roadmap to emotional healing.  JJ is passionate about empowering people with the knowledge and awareness of how they can live the life of their dreams. http://jjflizanes.com    

Rewiring Your Core Wound Patterns September 2023 http://jjflizanes.com/rewire   VIP Day with JJ for an Emotional Breakthrough http://jjflizanes.com/VIP   Dr. Nasha Winters is a sought-after luminary and global healthcare authority in integrative cancer research. She consults with physicians around the world bridging ancient therapies with advancements in modern medicine in the digital era. A personal journey with cancer and a medical career spanning over 25 years has Dr. Nasha on a mission to educate and empower the nearly fifty percent of the population expected to have cancer in their lifetime.   JJ Flizanes is an Empowerment Strategist and the host of several podcasts including People's Choice Awards nominee Spirit, Purpose & Energy. JJ Flizanes works with conscious, spiritual truth seekers who want to remove emotional blocks to success. She helps people identify sabotaging patterns and transmute struggle into joy. Through a series of clarifying exercises, she is able to curate a personalized roadmap to emotional healing.  JJ is passionate about empowering people with the knowledge and awareness of how they can live the life of their dreams. http://jjflizanes.com    

Rewiring Your Core Wound Patterns September 2023 http://jjflizanes.com/rewire   VIP Day with JJ for an Emotional Breakthrough http://jjflizanes.com/VIP   Dr. Nasha Winters is a sought-after luminary and global healthcare authority in integrative cancer research. She consults with physicians around the world bridging ancient therapies with advancements in modern medicine in the digital era. A personal journey with cancer and a medical career spanning over 25 years has Dr. Nasha on a mission to educate and empower the nearly fifty percent of the population expected to have cancer in their lifetime.   JJ Flizanes is an Empowerment Strategist and the host of several podcasts including People's Choice Awards nominee Spirit, Purpose & Energy. JJ Flizanes works with conscious, spiritual truth seekers who want to remove emotional blocks to success. She helps people identify sabotaging patterns and transmute struggle into joy. Through a series of clarifying exercises, she is able to curate a personalized roadmap to emotional healing.  JJ is passionate about empowering people with the knowledge and awareness of how they can live the life of their dreams. http://jjflizanes.com    

Rewiring Your Core Wound Patterns September 2023 http://jjflizanes.com/rewire   VIP Day with JJ for an Emotional Breakthrough http://jjflizanes.com/VIP   Dr. Nasha Winters is a sought-after luminary and global healthcare authority in integrative cancer research. She consults with physicians around the world bridging ancient therapies with advancements in modern medicine in the digital era. A personal journey with cancer and a medical career spanning over 25 years has Dr. Nasha on a mission to educate and empower the nearly fifty percent of the population expected to have cancer in their lifetime.   JJ Flizanes is an Empowerment Strategist and the host of several podcasts including People's Choice Awards nominee Spirit, Purpose & Energy. JJ Flizanes works with conscious, spiritual truth seekers who want to remove emotional blocks to success. She helps people identify sabotaging patterns and transmute struggle into joy. Through a series of clarifying exercises, she is able to curate a personalized roadmap to emotional healing.  JJ is passionate about empowering people with the knowledge and awareness of how they can live the life of their dreams. http://jjflizanes.com    

"Personal Psychedelic Use: From Recreational to Therapeutic Use” takes a deep dive into the evolution of our co-founders' psychedelic use–from recreational users to therapeutic practitioners. They share how their journeys have shaped who they are as facilitators and as human beings. Our hosts commence by exploring their initial experiences with these powerful substances - recounting their unguided and naive ventures, expressing what they would have done differently, and revealing the pivotal lessons learned. They shed light on the stark contrast between recreational and therapeutic psychedelic experiences.The narrative takes a turn when they delve into their evolution towards intentional use. Listen to Nicholas Levich speak about his sources of inspiration for more profound experiences, while Jimmy Nguyen shares his secret to maintaining positive changes – tuning into his inner integrity.By unveiling their journey, filled with challenges and triumphs, they underscore the importance of structured ceremonial containers for psychedelic use. The episode concludes with an insightful reminder about the now readily available resources and support systems for exploring psychedelic medicine.Additional Resources:Episode Transcript‘I Just Had My First Psychedelic Experience–What Do I Do Now?How Your Psychedelic Experiences Evolve Over TimeHow to Create an Intention for Your Psychedelic ExperienceAbout Us:Psychedelic Passage is the nation's first psychedelic concierge service. Our platform connects clients with a pre-vetted network of trusted, local facilitators across the country. We serve as an independent body that moderates the network of facilitators who all have their own private practice, which means we can advocate for you without a conflict of interest. Our comprehensive vetting process ensures each hand-selected facilitator serves journeyers with integrity. The goal is to inspire trust, confidence, and lasting change for each journeyer. To date, our network of guides has facilitated hundreds of safe and transformational journeys for people all across the United States. Visit our website or book a consultation to speak with a highly knowledgeable psychedelic concierge. They will get to know you and your situation and you'll have all your questions answered.More Psychedelic Passage:Official WebsiteBook a ConsultationPsychedelic Passage StoreBlog PageYoutubeInstagram: @psychedelicpassage  Twitter: @psych_passageReddit: u/psychedelicpassageFeedback & Topic Suggestions BoxLike, share, and follow to stay connected with our growing community of psychedelic-curious folks!

Food is so much more than just fuel for our bodies. It's also a powerful connector.  Food brings us together with family and friends, and allows us to express and receive love and appreciation, spark new relationships, create memories, discover and care for the world around us, and even navigate and explore our inner emotional and spiritual landscape. Because food helps us feel connected, we may also reach for it in moments of disconnection, distress, isolation, and loneliness. We can turn to it for comfort, or for a sense of familiarity and reassurance. And that's because of a foundational, biochemical truth for every human being on this planet:  When we eat food, we feel better.  As Marc David unpacks in this episode, using food to self-soothe and comfort ourselves isn't all bad. In fact, the conscious use of food to feel better can actually be beneficial. Fifty-nine year old guest coaching client, Debra, endured the death of her late husband several years ago – and now finds herself again grieving the loss of a relationship – this time, a breakup.  In response to her grief and sadness, Debra has noticed she's started eating compulsively in the evenings. And she feels ashamed of having gained some extra weight in recent months. Follow their conversation, as Marc explores how the loss or absence of close relationships and social ties in our lives can mean we look to food to satisfy some of our most basic needs – and how, at different times in our life, that can be a therapeutic strategy.

Huberman Lab Key Takeaways Psilocybin's main effect is to mimic serotonin in a very specific way, leading to neuroplasticityThe goal of psilocybin is the adaptive rewiring of the brain, not just rewiring of the brain – you want to rewire that leads to new and interesting ideasClinical trials using psilocybin for the treatment of depression are outperforming standard therapy and SSRIs (and other antidepressants) A combination of psilocybin + talk therapy shows evidence of the strongest long-lasting resultsPsilocybin increases communication across the brain and reduces the hierarchical organization of the brain, broadening the flow of information (including interoception and exteroception)“During the psilocybin journey, people have the opportunity to learn new relationships between different sensory and emotional states. Those new relationships seem to persist long after the psychedelic journey is finished.” – Dr. Andrew HubermanBest practices for an effective guided psilocybin journey: Sit or lie down comfortably with eyes closed or an eye maskMusic is critical to the experience1 or more people present should not be on psilocybinNo food at least 4 hours prior to the journeyKey features of the trip from those who experience positive results: a sense of unity, sense of spirituality, sense of bliss at some point during the experience, insight, and learning about one's lifeCurrent clinical studies and areas of promise for psilocybin use: treatment resistance depression, cancer-related depression, and anxiety Newer studies are exploring use for alcohol abuse, tobacco addiction, OCD, and moreRead the full notes @ podcastnotes.orgIn this episode, I discuss what psilocybin is (chemically) and how it works at the cellular and neural circuit level to trigger neuroplasticity, which is our brain's ability to rewire itself in ways that lead to long-lasting shifts in our emotional, cognitive and behavioral patterns and abilities. I discuss the emerging clinical trial evidence for the use of psilocybin in the treatment of depression, addictions and other psychiatric challenges. I explain the typical duration and phases of a psilocybin journey, the different categories of dosages often used and I explain the importance of set, setting and support when using psychedelics. I explain which groups of people place themselves at great risk by taking psilocybin as well as groups that could benefit, and I highlight the rapidly changing legal and medical landscape around psilocybin. This episode is a thorough exploration of psilocybin from the scientific and clinical literature perspective and ought to be of interest to anyone curious about psilocybin, mental health, neuroplasticity and/or psychedelics more generally. For the full show notes, visit hubermanlab.com. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Eight Sleep: https://eightsleep.com/huberman ROKA: https://roka.com/huberman HVMN: https://hvmn.com/huberman LMNT: https://drinklmnt.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman Timestamps (00:00:00) Psilocybin, Legal Considerations (00:08:32) Sponsors: Eight Sleep, ROKA, HVMN (00:12:00) Psilocybin Becomes Psilocin in the Gut, Serotonin (00:17:00) The Serotonin 2A Receptor, Therapeutic Outcomes SSRIs vs. Psilocybin (00:21:40) Serotonin Receptor Expression; Visual Hallucinations & Eyes Closed (00:27:21) Safety & Cautions for Specific Patient Populations (00:29:13) Sponsor: AG1 (Athletic Greens) (00:30:28) Psilocybin, “Magic Mushrooms” Dosing, Micro-Dosing, “Heroic Doses” (00:36:21) Psychedelic Journey: Set, Setting & Support (00:43:43) Music & the Psilocybin Journey; Duration of Effects (00:48:58) Psilocybin & the Brain: Subjective Experiences, Perception (00:58:36) Sponsor: LMNT (00:59:48) Brain Networks & Therapeutic Outcomes (01:05:23) Creativity; Music, Emotionality & Psychedelic Journeys (01:12:39) Depression & Psychedelics as Neuroplasticity “Wedge” (01:16:53) Positive Psychedelic Journeys, Unity, “Oceanic Boundlessness” (01:25:23) “Bad Trips”, Anxiety & Physiological Sighs (01:32:57) Therapeutic Use of Psilocybin (01:36:11) Neuroplasticity, Structural Brain Changes & Psilocybin (01:48:08) Psychedelics: Therapeutic Breakthroughs & Depression (01:56:37) Combining Psilocybin Therapy & Talk Therapy, Antidepressant Effects (02:03:11) Psilocybin Experience & Mental Health (2:06:42) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Neural Network Newsletter, Social Media Title Card Photo Credit: Mike Blabac Disclaimer

In this episode, I discuss what psilocybin is (chemically) and how it works at the cellular and neural circuit level to trigger neuroplasticity, which is our brain's ability to rewire itself in ways that lead to long-lasting shifts in our emotional, cognitive and behavioral patterns and abilities. I discuss the emerging clinical trial evidence for the use of psilocybin in the treatment of depression, addictions and other psychiatric challenges. I explain the typical duration and phases of a psilocybin journey, the different categories of dosages often used and I explain the importance of set, setting and support when using psychedelics. I explain which groups of people place themselves at great risk by taking psilocybin as well as groups that could benefit, and I highlight the rapidly changing legal and medical landscape around psilocybin. This episode is a thorough exploration of psilocybin from the scientific and clinical literature perspective and ought to be of interest to anyone curious about psilocybin, mental health, neuroplasticity and/or psychedelics more generally. For the full show notes, visit hubermanlab.com. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Eight Sleep: https://eightsleep.com/huberman ROKA: https://roka.com/huberman HVMN: https://hvmn.com/huberman LMNT: https://drinklmnt.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman Timestamps (00:00:00) Psilocybin, Legal Considerations (00:08:32) Sponsors: Eight Sleep, ROKA, HVMN (00:12:00) Psilocybin Becomes Psilocin in the Gut, Serotonin (00:17:00) The Serotonin 2A Receptor, Therapeutic Outcomes SSRIs vs. Psilocybin (00:21:40) Serotonin Receptor Expression; Visual Hallucinations & Eyes Closed (00:27:21) Safety & Cautions for Specific Patient Populations (00:29:13) Sponsor: AG1 (Athletic Greens) (00:30:28) Psilocybin, “Magic Mushrooms” Dosing, Micro-Dosing, “Heroic Doses” (00:36:21) Psychedelic Journey: Set, Setting & Support (00:43:43) Music & the Psilocybin Journey; Duration of Effects (00:48:58) Psilocybin & the Brain: Subjective Experiences, Perception (00:58:36) Sponsor: LMNT (00:59:48) Brain Networks & Therapeutic Outcomes (01:05:23) Creativity; Music, Emotionality & Psychedelic Journeys (01:12:39) Depression & Psychedelics as Neuroplasticity “Wedge” (01:16:53) Positive Psychedelic Journeys, Unity, “Oceanic Boundlessness” (01:25:23) “Bad Trips”, Anxiety & Physiological Sighs (01:32:57) Therapeutic Use of Psilocybin (01:36:11) Neuroplasticity, Structural Brain Changes & Psilocybin (01:48:08) Psychedelics: Therapeutic Breakthroughs & Depression (01:56:37) Combining Psilocybin Therapy & Talk Therapy, Antidepressant Effects (02:03:11) Psilocybin Experience & Mental Health (2:06:42) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Neural Network Newsletter, Social Media Title Card Photo Credit: Mike Blabac Disclaimer

In this episode I talk with Mick Collins, occupational therapist, author and incredible human being. We talk all about spirituality and how it plays a role in our practice as occupational therapists. We explore spiritual emergencies (and how the medical system often mistakes these for mental illness), transpersonal occupational therapy, shadow work, therapeutic use of self, … 87 – Transpersonal Occupational Therapy, Soul Awakenings & Therapeutic Use of Self ft Mick Collins Read More »

In this episode I talk with Mick Collins, occupational therapist, author and incredible human being. We talk all about spirituality and how it plays a role in our practice as occupational therapists. We explore spiritual emergencies (and how the medical system often mistakes these for mental illness), transpersonal occupational therapy, shadow work, therapeutic use of self, … 87 – Transpersonal Occupational Therapy, Soul Awakenings & Therapeutic Use of Self ft Mick Collins Read More »

As pet parents, we'll do pretty much anything to help our fur babies feel better and age healthily. Whether they have joint pain, skin issues, anxiety, or more serious illnesses like cancer or epilepsy, there is proof that cannabis and mushroom extracts can improve our pets' health. That's why so many animal lovers are interested in what CBD could do to make life easier for our cats, dogs, birds, and any other mammals we might care for.In this episode, host (and double-dog mama) Brit Smith dives into the studies and incredible real-life results of treating animals with CBD with holistic pet expert Angela Ardolino. After studying Medical Cannabis for Therapeutic Use at the University of Vermont, Angela started using CBD and hemp extracts to treat animals at her rescue farm in Florida. She's since been able to stop seizures, she's helped injured chickens in pain, and she's even put four different kinds of cancer into remission in dogs, all by treating them with full-spectrum CBD.Brit and Angela discuss how cannabis extracts work to keep us and our pets healthy, what kinds of animal ailments we can help with CBD, and whether we should be feeding our pups tincture or CBD dog treats.They also cover how to know if CBD is ok to mix with other medications our pets might be on, and how to find your pet's starting dose for common issues like anxiety before fireworks or storms.Follow us on social media @DifferentLeaf, and find host Brit Smith @BritTheBritish (including pics of her perfect pups!)Buy any issues of Different Leaf magazine at DifferentLeaf.com or find your local in-person retailer at DifferentLeaf.com/on-the-newsstandsFind DL's new merch line at xDifferentLeaf.com

The Root Cause Medicine Podcast is created by Rupa Health, the best way to order, track & get results from 30+ lab companies in one place. This episode is sponsored by Athletic Greens. With one delicious scoop of AG1, you get 75 high-quality vitamins, minerals, whole-food sourced ingredients, probiotics, and adaptogens to help support your gut health, nervous system, immune system, energy, recovery… All the things. In today's episode, Dr. Carrie Jones is joined by Dr. Erica Zelfand, a Therapeutic Psychedelic Expert and Educator. They discuss the therapeutic use of Ayahuasca, MDMA, Ketamine, and Psilocybin for depression, anxiety, addiction, PTSD, panic, and more. Key Takeaways from this episode: 1. What makes psychedelic medicine unique? When people hear the word psychedelic, they think of illegal drugs. However, psychedelic substances can be used for therapeutic purposes and help with addiction, PTSD, depression, or anxiety. The problem is that according to the Drug Enforcement Agency, there's no approved use for these substances, so there are no legal premises to use them. There are a few key medical facilities studying psychedelic medicine with their patients including Johns Hopkins and the U.S. Department of Veteran Affairs. 2. The science behind psychedelics: Psilocybin, Ayahuasca, MDMA, and Ketamine. Some of the most used psychedelic substances are Psilocybin, Ayahuasca, MDMA, LSD, and Ketamine. Psilocybin is the active constituent in magic mushrooms and is in the spotlight now. It is a constituent found in over 200 different species of fungi, which performed very well in clinical trials for treating things like depression, major depressive disorder, and various addictions. Ayahuasca is a psychedelic medicine that comes to us from the Amazon and is a combination of two different plants brewed together. MDMA has a good chance of being legalized within the next few years because of its healing trauma and post-traumatic stress disorder properties. Ketamine is a versatile psychedelic used in pediatrics, pets, surgeries, or dental procedures. It also can be used to treat addiction, but you have to be careful with it as it is an addictive substance in itself. 3. How can you get started with psychedelics correctly? Never buy and do psychedelics on your own. A safer way to do psychedelics is to go to a trusted professional. With Ketamine (for example), that means finding a licensed Ketamine practitioner or clinic. You can also enroll in a clinical trial supported by organizations like Multidisciplinary Association for Psychedelic Studies. Certain states such as Oregon and Colorado are also moving towards broadening psychedelic therapeutics in a clinical setting. Dr. Erica Zelfand is a licensed Naturopathic Doctor, specializing in integrative and functional family medicine. She is also a medical writer, editor, and speaker. Dr. Erica is a psychedelic expert and educator who helps people understand how the newly evolving world of therapeutic psychedelics such as Psilocybin and Ketamine help with depression, addiction, and more.

What are Psychedelics? Clinical Trials using Psychedelics Possible clinical application for Psychedelics What do Psychedelics feel like? Dose and Frequency Importance of Set and Setting The Darkside of Psychedelics The future of Psychedelic legalization   And so much more! .   Links mentioned in this episode! . Discounts mentioned on this show at https://burnitnutrition.com/podcast133/ . . Receive a complimentary Metabolic Profiling assessment and a 30-minute consultation with a MetPro expert at  https://metpro.co/burnit . . . Order ZBiotics at http://zbiotics.com/burnit Use code BURNIT and get 15% off on your first order! . . . BiOptimizers P3-OM - Get 10% off at www.p3om.com/burnit with coupon code burnit10.  . . . Get a FREE LMNT sample pack with any purchase. Limit one per customer at  http://drinklmnt.com/Burnit . . . Podcast Shop Page for 5th Stage Keto Body Transformation & Vitamin C Powder at https://burnitnutrition.com/shop  . Learn more about Paul Austin and Third Wave: Website: https://thethirdwave.co/ About Paul: https://thethirdwave.co/author-paul-austin/   . Leave me a rating & review on Apple Podcasts: https://itunes.apple.com/us/podcast/burn-it-nutrition-podcast/id1195955730?mt=2  . Follow Joseph Navarro on Instagram under @BurnitNutrition . Follow Joseph Navarro on Facebook under @BurnitNutrition . Thank You for Listening!! Please share this episode! Be the one who helps spark a transformation in your family! Feedback to share? Send email to info@BurnitNutrition.com Subscribe! Don't miss another episode! Notice of Sponsorship Affiliate Disclosure with MetPro, Amazon, BiOptimizers, LMNT, ZBiotics . Please read the full medical disclaimer  burnitnutrition.com/medical-disclaimer/

Such a fabulous conversation with the fantastic Marisa Sullivan. This conversation was rich with all things sex magic. This juicy episode is filled with tasty tidbits, tools and gorgeous insight!    Marisa Sullivan is a Modern Day Mystic, based in Brooklyn, NY.  She is a Soccer Mom, a  Tantrika,  a Pleasure Witch.  She teaches Women, Folks, and Couples Sexual Empowerment and Sacred Sexuality.  She coaches Decolonizing Sexual Health Practices such as Womb Steaming and Breast/Chest Massage.  She counsels how to maximize the magic and medicine of sexual juiciness, how to be authentic in our sexual expression, inhabiting our yes and no and understanding the power of pleasure, not just in Sexuality, but Joy and Pleasure in our bodies and everyday life. Her certifications include multiple Yoga Systems, (and meditation) Pelvic Floor Yoga, Pre and Post Natal, Reiki Masters, Womb Steaming, Deep Study of The Wheel of Consent, and a Masters in Theater for Educational and Therapeutic Use.     If you are craving a rich, amazing convo: this one's for you!  We are talking about:  

The development of penicillin started – but definitely did not end – with the chance discovery of some mold in a petri dish. There is so much more to the story. Research: Bernard, Diane. “How a miracle drug changed the fight against infection during World War II.” Washington Post. 7/11/2020. https://www.washingtonpost.com/history/2020/07/11/penicillin-coronavirus-florey-wwii-infection/ British Library. “Inventor(s) of the month, Alexander Fleming and the story of Penicillin.” 7/28/2021. https://blogs.bl.uk/business/2021/07/inventors-of-the-month-alexander-fleming.html Chain, E. et al. “Penicillin as a Chemotherapeutic Agent.” The Lancet. Vol. 236, Issue 6104. 8/24/1940. https://doi.org/10.1016/S0140-6736(01)08728-1 Fleming A. On the Antibacterial Action of Cultures of a Penicillium, with Special Reference to their Use in the Isolation of B. influenzæ. Br J Exp Pathol. 1929 Jun;10(3):226–36. PMCID: PMC2048009. Gaynes, Robert. “The Discovery of Penicillin—New Insights After More Than 75 Years of Clinical Use.” Emerg Infect Dis. 2017 May; 23(5): 849–853.. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403050/ Lee, Victoria. “Microbial Transformations.” Historical Studies in the Natural Sciences, SEPTEMBER 2018, Vol. 48, No. 4. Via JSTOR. https://www.jstor.org/stable/10.2307/26507225 National Museums of Scotland. “Culture Vessel.” https://www.nms.ac.uk/explore-our-collections/stories/science-and-technology/culture-vessel/ Quinn, Roswell. “Rethinking Antibiotic Research and Development: World War II and the Penicillin Collaborative.” American Journal of Public Health | March 2013, Vol 103, No. 3. Scibilia, Anthony Julius. “Being Prometheus in 1943:: Bringing Penicillin to the Working Man.” Pennsylvania History: A Journal of Mid-Atlantic Studies , Vol. 80, No. 3 (Summer 2013). https://www.jstor.org/stable/10.5325/pennhistory.80.3.0442 Science History. “Alexander Fleming.” 12/5/2017. https://www.sciencehistory.org/historical-profile/alexander-fleming Science Museum. “How Was Penicillin Developed?” 2/23/2021. https://www.sciencemuseum.org.uk/objects-and-stories/how-was-penicillin-developed Shama, Gilbert. “'Déjà Vu' – The Recycling of Penicillin in Post-liberation Paris.” Pharmacy in History , 2013, Vol. 55, No. 1 (2013). Via JSTOR. https://www.jstor.org/stable/23645718 The Alexander Fleming Laboratory Museum, London, UK. “The Discovery and Development of Penicillin 1928-1945.” 11/19/1999. https://www.acs.org/content/dam/acsorg/education/whatischemistry/landmarks/flemingpenicillin/the-discovery-and-development-of-penicillin-commemorative-booklet.pdf Wainwright, Milton. “Moulds in Folk Medicine.” Folklore , 1989, Vol. 100, No. 2 (1989). https://www.jstor.org/stable/1260294 Wainwright, Milton. “The History of the Therapeutic Use of Crude Penicillin.” Medical History, 1987, 31: 41-50. Williams KJ. The introduction of 'chemotherapy' using arsphenamine - the first magic bullet. J R Soc Med. 2009 Aug;102(8):343-8. doi: 10.1258/jrsm.2009.09k036. PMID: 19679737; PMCID: PMC2726818. Wood, Jonathan. “Penicillin: The Oxford Story.” Oxford News Blog. 7/16/2010. https://www.ox.ac.uk/news/science-blog/penicillin-oxford-story Zaffiri, Lorenzo et al. “History of Antibiotics. From Salvarsan to Cephalosporins.” Journal of Investigative Surgery, 25, 67–77, 2012.  See omnystudio.com/listener for privacy information.

Dr. Clancy Cavnar, PsyD, a clinical psychologist and co-editor of the book, The Therapeutic Use of Ayahuasca, discusses the healing benefits of using ayahuasca, especially for treating trauma and addiction. People often report a numinous or spiritual quality to their psychedelic experiences that serve as the foundation for healing and change. These spiritual awakenings can't be tested by the scientific method but are a profound component of the therapeutic experience. Dr. Cavnar shares her knowledge and wisdom on the world of ayahuasca and shamanism through the lens of her experience as a Western clinical psychologist.

Ashwagandha is an important herb used in the ancient Indian system of medicine known as Ayurveda to promote general health and well-being. In Ayurvedic practice, ashwagandha is classified as a Rasayana, which means an herb or preparation that rejuvenates, extends life, and promotes a youthful state of physical and mental health. Listen in to discover more about ashwagandha's incredible health benefits in general and a special potent “superhero” form known as KSM-66 ashwagandha.   What Does Ashwagandha Do? Ashwagandha's superpower is that it is an adaptogen. Adaptogens are non-toxic therapies that normalize our bodily functions – both physical and mental – that are thrown out of balance when we are exposed to chronic, uncontrolled stress. They do so by correcting imbalances in the neuroendocrine and immune systems [2]. In short, adaptogens enhance our ability to cope with stress. There are more than 35 natural compounds in ashwagandha including alkaloids, steroidal lactones, saponins, and with anolides. These compounds have been shown to have anti-stress activity in multiple laboratory models of chronic stress and in some human studies as well [1-5]. Additionally, ashwagandha extracts as well as specific bioactive compounds present in this plant – primarily in the roots – have been shown to help: counter pain and joint swelling associated with arthritis boost various components of the immune system protect the brain and nervous system slow down or even kill abnormal cells enhance both male and female sexual desire and function What Is KSM-66 Ashwagandha? KSM-66 Ashwagandha is a high-concentration ashwagandha root extract manufactured and sold by Ixoreal Biomed, located in Hyderabad, India [6]. Ashwagandha KSM-66 is made solely from ashwagandha roots, which contain its main bioactive ingredients, without using any other parts that are considered to be less effective. A unique feature of KSM-66 ashwagandha is that it's standardized to a withanolide content of at least 5 percent. Withanolides are a group of around 300 naturally occurring steroid compounds, some of which are naturally present in ashwagandha. One example is Withaferin A, an anti-inflammatory compound that has also been shown to stop tumors from growing their own blood vessels, slowing down their growth, and perhaps even shrinking them. Last but not least, KSM-66 ashwagandha is produced by a unique extraction process, based on the principles of “green chemistry,” without using alcohol or any synthetic solvents. Let's take a closer look now at some of KSM-66 ashwagandha's benefits for health.   What Too Much Cortisol Does to the Body Any stressful event in our lives causes our adrenal glands to produce cortisol, a steroid hormone that acts to control blood sugar levels, regulate metabolism, lower inflammation levels, influence memory formation, and manage salt and water balance [7]. The more stressed we are and the longer we're stressed, the more our adrenals respond by releasing cortisol into our bloodstream. Too much cortisol in the blood over a prolonged period of time can lead to: rapid weight gain high blood pressure osteoporosis muscle weakness mood swings anxiety, depression, or irritability increased thirst and frequency of urination [7] Ongoing high cortisol levels can also eventually cause a lack of sex drive in men. In women, periods typically become irregular, less frequent, or may even stop altogether (amenorrhea).   How Can Ashwagandha Help Us Cope With Stress? To answer this question, a double-blind, randomized, placebo-controlled trial was conducted to assess the safety and efficacy of KSM-66 ashwagandha (which, as mentioned above, is a high-concentration, full-spectrum ashwagandha root extract) in 64 adults [5]. After 60 days of treatment, the study authors observed a “substantial reduction” in four separate measures of stress in the study participants. KSM-66 ashwagandha also reduced levels of the hormone cortisol in the blood. By lowering cortisol, ashwagandha tones down the body's response to stressful situations, in effect “calming us down.”   No serious adverse events were reported [5] and the study researchers concluded that: “High-concentration full-spectrum Ashwagandha root extract safely and effectively improves an individual's resistance towards stress and thereby improves self-assessed quality of life.” Similarly, in another randomized, double-blind, placebo-controlled study, 60 stressed but otherwise healthy adults were randomly assigned to take either a placebo or an ashwagandha root extract once daily for 2 months [8]. At the end of the study, participants given ashwagandha showed a significant reduction in their stress, anxiety, and depression scores. Once again, ashwagandha consumption was associated with a greater reduction in the levels of cortisol in the blood, when compared with placebo [8].   The Connection Between Stress and Obesity Chronic stress has been associated with many illnesses, including obesity. In a double-blind, randomized, placebo-controlled trial, ashwagandha consumption was seen to lead to significant reductions in emotional and uncontrolled food cravings while also lowering cortisol, body weight, and body mass index (BMI) in 52 subjects subjected to chronic stress [9]. Indeed, laboratory experiments in mice have shown that one of the main active ingredients in ashwagandha known as Withaferin A can protect against obesity caused by a high-fat diet by reducing inflammation in the liver, oxidative stress, and insulin resistance [10]. These and other findings make it clear that ashwagandha is a powerful tool in our battle against ongoing stress, likely by regulating various specific aspects of our hypothalamus-pituitary-adrenal (HPA) axis. This is an interactive neuroendocrine system that plays a key role in maintaining our body's internal equilibrium, along with orchestrating our body's response to stress.   Ashwagandha Benefits for Joint Pain Ashwagandha is a key ingredient in many Ayurvedic formulations prescribed for joint-related conditions such as osteoarthritis. Indeed, many research studies show that ashwagandha and its bioactive ingredients help to manage and reduce inflammation levels. For instance, in a double-blind, placebo-controlled cross-over clinical trial published in 1991, 42 patients with osteoarthritis were randomized to receive a formula containing ashwagandha, frankincense, turmeric, and zinc – or placebo – for three months [11]. Clinical efficacy was evaluated every 15 days in terms of severity of pain, morning stiffness, Ritchie articular index (a weighted score of tenderness and swelling in 53 joint groups, each scored on a 0-3 scale), joint score, disability score, and grip strength. Throughout the study, the herbal formula was seen to significantly reduce the severity of joint pain and disability. No significant adverse effects were reported. In another study, 86 patients with joint pain were given 5 grams of ashwagandha powder twice a day for three weeks with lukewarm water or milk [12]. Then these patients took another Ayurvedic preparation known as Sidh Makardhwaj – a formulation used in rheumatoid arthritis and neurological disorders – daily for the next four weeks. Treatment with ashwagandha and Sidh Makardhwaj for seven weeks led to significantly improved scores of joint swelling, tenderness, and pain, indicating that this combination treatment is likely to be beneficial in rheumatoid arthritis. Indeed, in laboratory experiments, an ashwagandha root extract was seen to reduce inflammation in knee cartilage taken from chronic osteoarthritis patients [13].   Ashwagandha for Boosting Endurance, Muscle Strength, and Recovery Ashwagandha has long had the reputation of being able to enhance cardiovascular endurance and physical performance. As stated earlier, consuming this herb is said to impart the strength and stamina of a horse [1]. In a prospective, double-blind, randomized, and placebo-controlled study, KSM-66 ashwagandha was shown to significantly boost cardiorespiratory endurance and improve self-reported quality of life (QOL) in 50 healthy male and female athletic adults [14]. In another randomized, prospective, double-blind, placebo-controlled clinical study, 57 young men with little previous experience in resistance training were randomized into treatment and placebo groups [15]. Participants in the treatment group consumed 300 mg of ashwagandha root extract twice daily, while those in the control group took starch placebos instead. Multiple measurements – including muscle strength, muscle size, body composition, testosterone levels, and muscle recovery – were made before the start of the study. Both groups then went through resistance training for 8 weeks and the measurements were repeated when they were done. Promisingly, the group of men taking ashwagandha root extract had significantly greater increases in muscle strength and arm muscle size relative to the placebo group. They also showed significantly less exercise-induced muscle damage, higher testosterone levels, and a greater reduction in body fat percentage. In other words, ashwagandha supplementation is associated with significant increases in muscle mass, strength, and recovery after exercise. In another randomized, double-blind strength and conditioning study known as the STAR trial, 500 mg of an extract of ashwagandha roots and leaves was consumed by recreationally active young men for 12 weeks [16]. Body composition, muscular strength, power, and endurance, cycling time trial, and blood chemistry were measured before and after the study. Consuming the ashwagandha extract was seen to improve upper and lower body strength and improve distribution of body mass in these men, once again without causing any serious adverse effects.   Ashwagandha as an Immune System Enhancer Ashwagandha enhances immune function. In a small study, ashwagandha root extract was seen to activate multiple types of immune cells in the participants [17]. Similarly, a tea fortified with five herbs including ashwagandha was seen to activate so-called “natural killer” (NK) cells in not just one, but two independent double-blind intervention studies conducted in India on healthy volunteers [18]. NK cell activity is an important aspect of our body's early immune response to infections. Interestingly, in other situations, ashwagandha extracts have also been shown to suppress specific components of the immune system. For example, one of the characteristic features of rheumatoid arthritis (RA) is the continuous production of pro-inflammatory compounds known as cytokines in joint cavities, triggering inflammation and cartilage destruction. In laboratory experiments in rats, a root extract of ashwagandha was seen to suppress production of pro-inflammatory cytokines and reduce oxidative stress [19].   The Brain-Boosting Benefits of Ashwagandha Numerous laboratory studies show that ashwagandha – traditionally used in Ayurveda to boost intellect and memory – can slow, stop, and reverse damage to brain cells and may even help to reconstruct brain cell networks. For instance, ashwagandha extracts have been shown to promote nerve cell growth in culture [20]. Withanolide A, withanoside IV, and withanoside VI were identified as the bioactive compounds responsible. Ashwagandha extracts as well as specific bioactive compounds (e.g., withanolide A) have also been shown to protect nerve cells in culture against damage caused by various toxic agents [21]. Amazingly, the administration of withanoside IV for 21 days led to recovery in a rat model of spinal cord damage [20]. It is well known that toxic free radicals damage brain cells and contribute to both normal aging and aging-related health conditions. In a 2015 study, both ashwagandha extracts and a bioactive compound known as withanone were seen to protect nerve cells from oxidative damage [22]. Not surprisingly, ashwagandha has long been used in Ayurveda to enhance memory and improve mental faculties. In a randomized, double-blind, placebo-controlled pilot study, 50 adults suffering from mild cognitive impairment (MCI) – who are considered to be at a greater risk of developing dementia later in life – were treated with either 300 mg of KSM-66 ashwagandha twice daily or placebo for 8 weeks [23]. After 8 weeks, the ashwagandha KSM-66 group showed significant improvements in both their immediate or short-term as well as general memory, relative to the placebo group. The ashwagandha group also showed significant improvements in executive function, sustained attention, and information-processing abilities.   Can Ashwagandha Even Help Protect Against Abnormal Cell Growth? Ashwagandha and other species of Withania are well known in folk medicine traditions for their anti-cancer properties and their extracts have been shown to be toxic for multiple types of cancer cells in laboratory experiments [24]. They appear to act by slowing down or even stopping cancer cell growth by inducing programmed cell death or “apoptosis.” As stated earlier, Withaferin A, an anti-inflammatory withanolide, has been shown to act as an anti-angiogenic. In other words, it can help stop tumors from growing their own blood vessels, slowing down their growth, or perhaps even shrinking them. As reported in the journal Biochemical Pharmacology in August 2019, growing evidence suggests that Withaferin A is very effective against cancer [25]. For instance, low response rate and recurrence are common issues in lung cancer. Withaferin A has been shown to exhibit potent toxicity against several lung cancer cell lines in laboratory experiments. Not only that, the combination of Withaferin A and chemotherapeutic drugs were shown to have additive effects on lung cancer cell survival [26]. Withaferin A has also been shown to be toxic for breast cancer and cervical cancer (HeLa) cells in laboratory experiments [27,28]. Similarly, other bioactive compounds in ashwagandha have also been shown to be toxic for cancer cells in laboratory experiments [29].   KSM-66 Ashwagandha's Impact on Libido and Infertility Ashwagandha root extract has been shown to enhance sexual desire and function in both men and women. For instance, ashwagandha has been described in Ayurvedic medicine as an aphrodisiac that can be used to treat male sexual dysfunction and infertility. In a pilot study conducted to evaluate the effects of ashwagandha in patients with a low sperm count (known as oligospermia), a total of 46 male patients were randomized either to treatment with KSM-66 Ashwagandha or placebo for 90 days [30]. At the end of the study, participants given KSM-66 ashwagandha showed a 167% increase in sperm count, a 53% increase in semen volume, and a 57% increase in sperm motility relative to baseline. In comparison, only minimal changes were seen in the placebo group. Further, a greater improvement in hormone levels was seen with KSM-66 ashwagandha. In other words, ashwagandha is likely to be very effective in treating oligospermia, which is a leading cause of male infertility. Similarly, a meta-analysis showed that ashwagandha significantly improved sperm concentration and sperm motility even in men with normal sperm parameters, without any adverse effects [31]. Ashwagandha has also been shown to enhance sexual function in women. At the Trupti Hospital and Santati Fertility Center located near Mumbai in India, 50 women were randomized to either ashwagandha treatment or placebo (300 mg twice daily) for 8 weeks [32]. In this study, ashwagandha supplementation was shown to lead to significantly higher scores in multiple markers of sexual desire and function.   But Is Ashwagandha Safe? Ashwagandha root powder has been used in Ayurvedic medicine for centuries, and it is believed to be completely safe and free of any toxicity. Extracts of ashwagandha made using alcohol and water will likely contain higher doses of its natural ingredients, relative to raw powder. So far animal studies with such extracts have shown no evidence of toxicity, even at relatively high doses [33]. However, it is always advisable to take an herbal supplement only after consulting your healthcare provider, especially if you have any ongoing health conditions or if you're pregnant or breastfeeding.   Organixx Turmeric 3D Contains KSM-66 Ashwagandha The Organixx Turmeric 3D formula has always contained ashwagandha extract. As part of our commitment to seeking out the cleanest and most effective supplement ingredients, we upgraded to KSM-66 Ashwagandha in 2019 – the most clinically studied ashwagandha on the market. KSM-66 is a full-spectrum extract produced using a unique proprietary extraction process, based on “Green Chemistry” principles, without using alcohol or any other chemical solvent.   Resources: [1] An Overview on Ashwagandha: A Rasayana (Rejuvenator) of Ayurveda. [2] Scientific basis for the use of Indian ayurvedic medicinal plants in the treatment of neurodegenerative disorders: ashwagandha. [3] Scientific Basis for the Therapeutic Use of Withania somnifera (Ashwagandha): A Review. [4] Anti‐stress activity of sitoindosides VII and VIII, new acylsterylglucosides from Withania somnifera. [5] A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults. [6] KSM-66 Ashwagandha Documentary [7] Society for Endocrinology: You and Your Hormones – Cortisol. [8] An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study. [9] Body Weight Management in Adults Under Chronic Stress Through Treatment With Ashwagandha Root Extract: A Double-Blind, Randomized, Placebo-Controlled Trial. [10] Withaferin A Protects Against High-Fat Diet-Induced Obesity Via Attenuation of Oxidative Stress, Inflammation, and Insulin Resistance. [11] Treatment of osteoarthritis with a herbomineral formulation: a double-blind, placebo-controlled, cross-over study. [12] Efficacy & safety evaluation of Ayurvedic treatment (Ashwagandha powder & Sidh Makardhwaj) in rheumatoid arthritis patients: a pilot prospective study. [13] The relationship between chondroprotective and antiinflammatory effects of Withania somnifera root and glucosamine sulphate on human osteoarthritic cartilage in vitro. [14] Efficacy of Ashwagandha (Withania somnifera [L.] Dunal) in improving cardiorespiratory endurance in healthy athletic adults. [15] Examining the effect of Withania somnifera supplementation on muscle strength and recovery: a randomized controlled trial. [16] Effects of an Aqueous Extract of Withania somnifera on Strength Training Adaptations and Recovery: The STAR Trial. [17] In vivo effects of Ashwagandha (Withania somnifera) extract on the activation of lymphocytes. [18] In vivo enhancement of natural killer cell activity through tea fortified with Ayurvedic herbs. [19] In vivo, Extract from Withania somnifera Root Ameliorates Arthritis via Regulation of Key Immune Mediators of Inflammation in Experimental Model of Arthritis. [20] Effects of Ashwagandha (roots of Withania somnifera) on neurodegenerative diseases. [21] Neuritic regeneration and synaptic reconstruction induced by withanolide A. [22] Combinations of Ashwagandha leaf extracts protect brain-derived cells against oxidative stress and induce differentiation. [23] Efficacy and Safety of Ashwagandha (Withania somnifera (L.) Dunal) Root Extract in Improving Memory and Cognitive Functions. [24] Medicinal Plants from Near East for Cancer Therapy. [25] Withaferin A: From ayurvedic folk medicine to preclinical anti-cancer drug. [26] Identification of Withaferin A as a Potential Candidate for Anti-Cancer Therapy in Non-Small Cell Lung Cancer. [27] Withaferin A inhibits expression of ataxia telangiectasia and Rad3-related kinase and enhances sensitivity of human breast cancer cells to cisplatin. [28] Subcritical water extraction of withanosides and withanolides from ashwagandha (Withania somnifera L) and their biological activities. [29] Cytotoxic Withanolides from the Roots of Indian Ginseng (Withania somnifera). [30] Clinical Evaluation of the Spermatogenic Activity of the Root Extract of Ashwagandha (Withania somnifera) in Oligospermic Males: A Pilot Study. [31] Withania somnifera (Indian ginseng) in male infertility: An evidence-based systematic review and meta-analysis. [32] Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Improving Sexual Function in Women: A Pilot Study. [33] Safety assessment of Withania somnifera extract standardized for Withaferin A: Acute and sub-acute toxicity study. KSM-66 Ashwagandha: A Superhero Herb for Body & Brain

Ashwagandha is an important herb used in the ancient Indian system of medicine known as Ayurveda to promote general health and well-being. In Ayurvedic practice, ashwagandha is classified as a Rasayana, which means an herb or preparation that rejuvenates, extends life, and promotes a youthful state of physical and mental health. Listen in to discover more about ashwagandha's incredible health benefits in general and a special potent “superhero” form known as KSM-66 ashwagandha.   What Does Ashwagandha Do? Ashwagandha's superpower is that it is an adaptogen. Adaptogens are non-toxic therapies that normalize our bodily functions – both physical and mental – that are thrown out of balance when we are exposed to chronic, uncontrolled stress. They do so by correcting imbalances in the neuroendocrine and immune systems [2]. In short, adaptogens enhance our ability to cope with stress. There are more than 35 natural compounds in ashwagandha including alkaloids, steroidal lactones, saponins, and with anolides. These compounds have been shown to have anti-stress activity in multiple laboratory models of chronic stress and in some human studies as well [1-5]. Additionally, ashwagandha extracts as well as specific bioactive compounds present in this plant – primarily in the roots – have been shown to help: counter pain and joint swelling associated with arthritis boost various components of the immune system protect the brain and nervous system slow down or even kill abnormal cells enhance both male and female sexual desire and function What Is KSM-66 Ashwagandha? KSM-66 Ashwagandha is a high-concentration ashwagandha root extract manufactured and sold by Ixoreal Biomed, located in Hyderabad, India [6]. Ashwagandha KSM-66 is made solely from ashwagandha roots, which contain its main bioactive ingredients, without using any other parts that are considered to be less effective. A unique feature of KSM-66 ashwagandha is that it's standardized to a withanolide content of at least 5 percent. Withanolides are a group of around 300 naturally occurring steroid compounds, some of which are naturally present in ashwagandha. One example is Withaferin A, an anti-inflammatory compound that has also been shown to stop tumors from growing their own blood vessels, slowing down their growth, and perhaps even shrinking them. Last but not least, KSM-66 ashwagandha is produced by a unique extraction process, based on the principles of “green chemistry,” without using alcohol or any synthetic solvents. Let's take a closer look now at some of KSM-66 ashwagandha's benefits for health.   What Too Much Cortisol Does to the Body Any stressful event in our lives causes our adrenal glands to produce cortisol, a steroid hormone that acts to control blood sugar levels, regulate metabolism, lower inflammation levels, influence memory formation, and manage salt and water balance [7]. The more stressed we are and the longer we're stressed, the more our adrenals respond by releasing cortisol into our bloodstream. Too much cortisol in the blood over a prolonged period of time can lead to: rapid weight gain high blood pressure osteoporosis muscle weakness mood swings anxiety, depression, or irritability increased thirst and frequency of urination [7] Ongoing high cortisol levels can also eventually cause a lack of sex drive in men. In women, periods typically become irregular, less frequent, or may even stop altogether (amenorrhea).   How Can Ashwagandha Help Us Cope With Stress? To answer this question, a double-blind, randomized, placebo-controlled trial was conducted to assess the safety and efficacy of KSM-66 ashwagandha (which, as mentioned above, is a high-concentration, full-spectrum ashwagandha root extract) in 64 adults [5]. After 60 days of treatment, the study authors observed a “substantial reduction” in four separate measures of stress in the study participants. KSM-66 ashwagandha also reduced levels of the hormone cortisol in the blood. By lowering cortisol, ashwagandha tones down the body's response to stressful situations, in effect “calming us down.”   No serious adverse events were reported [5] and the study researchers concluded that: “High-concentration full-spectrum Ashwagandha root extract safely and effectively improves an individual's resistance towards stress and thereby improves self-assessed quality of life.” Similarly, in another randomized, double-blind, placebo-controlled study, 60 stressed but otherwise healthy adults were randomly assigned to take either a placebo or an ashwagandha root extract once daily for 2 months [8]. At the end of the study, participants given ashwagandha showed a significant reduction in their stress, anxiety, and depression scores. Once again, ashwagandha consumption was associated with a greater reduction in the levels of cortisol in the blood, when compared with placebo [8].   The Connection Between Stress and Obesity Chronic stress has been associated with many illnesses, including obesity. In a double-blind, randomized, placebo-controlled trial, ashwagandha consumption was seen to lead to significant reductions in emotional and uncontrolled food cravings while also lowering cortisol, body weight, and body mass index (BMI) in 52 subjects subjected to chronic stress [9]. Indeed, laboratory experiments in mice have shown that one of the main active ingredients in ashwagandha known as Withaferin A can protect against obesity caused by a high-fat diet by reducing inflammation in the liver, oxidative stress, and insulin resistance [10]. These and other findings make it clear that ashwagandha is a powerful tool in our battle against ongoing stress, likely by regulating various specific aspects of our hypothalamus-pituitary-adrenal (HPA) axis. This is an interactive neuroendocrine system that plays a key role in maintaining our body's internal equilibrium, along with orchestrating our body's response to stress.   Ashwagandha Benefits for Joint Pain Ashwagandha is a key ingredient in many Ayurvedic formulations prescribed for joint-related conditions such as osteoarthritis. Indeed, many research studies show that ashwagandha and its bioactive ingredients help to manage and reduce inflammation levels. For instance, in a double-blind, placebo-controlled cross-over clinical trial published in 1991, 42 patients with osteoarthritis were randomized to receive a formula containing ashwagandha, frankincense, turmeric, and zinc – or placebo – for three months [11]. Clinical efficacy was evaluated every 15 days in terms of severity of pain, morning stiffness, Ritchie articular index (a weighted score of tenderness and swelling in 53 joint groups, each scored on a 0-3 scale), joint score, disability score, and grip strength. Throughout the study, the herbal formula was seen to significantly reduce the severity of joint pain and disability. No significant adverse effects were reported. In another study, 86 patients with joint pain were given 5 grams of ashwagandha powder twice a day for three weeks with lukewarm water or milk [12]. Then these patients took another Ayurvedic preparation known as Sidh Makardhwaj – a formulation used in rheumatoid arthritis and neurological disorders – daily for the next four weeks. Treatment with ashwagandha and Sidh Makardhwaj for seven weeks led to significantly improved scores of joint swelling, tenderness, and pain, indicating that this combination treatment is likely to be beneficial in rheumatoid arthritis. Indeed, in laboratory experiments, an ashwagandha root extract was seen to reduce inflammation in knee cartilage taken from chronic osteoarthritis patients [13].   Ashwagandha for Boosting Endurance, Muscle Strength, and Recovery Ashwagandha has long had the reputation of being able to enhance cardiovascular endurance and physical performance. As stated earlier, consuming this herb is said to impart the strength and stamina of a horse [1]. In a prospective, double-blind, randomized, and placebo-controlled study, KSM-66 ashwagandha was shown to significantly boost cardiorespiratory endurance and improve self-reported quality of life (QOL) in 50 healthy male and female athletic adults [14]. In another randomized, prospective, double-blind, placebo-controlled clinical study, 57 young men with little previous experience in resistance training were randomized into treatment and placebo groups [15]. Participants in the treatment group consumed 300 mg of ashwagandha root extract twice daily, while those in the control group took starch placebos instead. Multiple measurements – including muscle strength, muscle size, body composition, testosterone levels, and muscle recovery – were made before the start of the study. Both groups then went through resistance training for 8 weeks and the measurements were repeated when they were done. Promisingly, the group of men taking ashwagandha root extract had significantly greater increases in muscle strength and arm muscle size relative to the placebo group. They also showed significantly less exercise-induced muscle damage, higher testosterone levels, and a greater reduction in body fat percentage. In other words, ashwagandha supplementation is associated with significant increases in muscle mass, strength, and recovery after exercise. In another randomized, double-blind strength and conditioning study known as the STAR trial, 500 mg of an extract of ashwagandha roots and leaves was consumed by recreationally active young men for 12 weeks [16]. Body composition, muscular strength, power, and endurance, cycling time trial, and blood chemistry were measured before and after the study. Consuming the ashwagandha extract was seen to improve upper and lower body strength and improve distribution of body mass in these men, once again without causing any serious adverse effects.   Ashwagandha as an Immune System Enhancer Ashwagandha enhances immune function. In a small study, ashwagandha root extract was seen to activate multiple types of immune cells in the participants [17]. Similarly, a tea fortified with five herbs including ashwagandha was seen to activate so-called “natural killer” (NK) cells in not just one, but two independent double-blind intervention studies conducted in India on healthy volunteers [18]. NK cell activity is an important aspect of our body's early immune response to infections. Interestingly, in other situations, ashwagandha extracts have also been shown to suppress specific components of the immune system. For example, one of the characteristic features of rheumatoid arthritis (RA) is the continuous production of pro-inflammatory compounds known as cytokines in joint cavities, triggering inflammation and cartilage destruction. In laboratory experiments in rats, a root extract of ashwagandha was seen to suppress production of pro-inflammatory cytokines and reduce oxidative stress [19].   The Brain-Boosting Benefits of Ashwagandha Numerous laboratory studies show that ashwagandha – traditionally used in Ayurveda to boost intellect and memory – can slow, stop, and reverse damage to brain cells and may even help to reconstruct brain cell networks. For instance, ashwagandha extracts have been shown to promote nerve cell growth in culture [20]. Withanolide A, withanoside IV, and withanoside VI were identified as the bioactive compounds responsible. Ashwagandha extracts as well as specific bioactive compounds (e.g., withanolide A) have also been shown to protect nerve cells in culture against damage caused by various toxic agents [21]. Amazingly, the administration of withanoside IV for 21 days led to recovery in a rat model of spinal cord damage [20]. It is well known that toxic free radicals damage brain cells and contribute to both normal aging and aging-related health conditions. In a 2015 study, both ashwagandha extracts and a bioactive compound known as withanone were seen to protect nerve cells from oxidative damage [22]. Not surprisingly, ashwagandha has long been used in Ayurveda to enhance memory and improve mental faculties. In a randomized, double-blind, placebo-controlled pilot study, 50 adults suffering from mild cognitive impairment (MCI) – who are considered to be at a greater risk of developing dementia later in life – were treated with either 300 mg of KSM-66 ashwagandha twice daily or placebo for 8 weeks [23]. After 8 weeks, the ashwagandha KSM-66 group showed significant improvements in both their immediate or short-term as well as general memory, relative to the placebo group. The ashwagandha group also showed significant improvements in executive function, sustained attention, and information-processing abilities.   Can Ashwagandha Even Help Protect Against Abnormal Cell Growth? Ashwagandha and other species of Withania are well known in folk medicine traditions for their anti-cancer properties and their extracts have been shown to be toxic for multiple types of cancer cells in laboratory experiments [24]. They appear to act by slowing down or even stopping cancer cell growth by inducing programmed cell death or “apoptosis.” As stated earlier, Withaferin A, an anti-inflammatory withanolide, has been shown to act as an anti-angiogenic. In other words, it can help stop tumors from growing their own blood vessels, slowing down their growth, or perhaps even shrinking them. As reported in the journal Biochemical Pharmacology in August 2019, growing evidence suggests that Withaferin A is very effective against cancer [25]. For instance, low response rate and recurrence are common issues in lung cancer. Withaferin A has been shown to exhibit potent toxicity against several lung cancer cell lines in laboratory experiments. Not only that, the combination of Withaferin A and chemotherapeutic drugs were shown to have additive effects on lung cancer cell survival [26]. Withaferin A has also been shown to be toxic for breast cancer and cervical cancer (HeLa) cells in laboratory experiments [27,28]. Similarly, other bioactive compounds in ashwagandha have also been shown to be toxic for cancer cells in laboratory experiments [29].   KSM-66 Ashwagandha's Impact on Libido and Infertility Ashwagandha root extract has been shown to enhance sexual desire and function in both men and women. For instance, ashwagandha has been described in Ayurvedic medicine as an aphrodisiac that can be used to treat male sexual dysfunction and infertility. In a pilot study conducted to evaluate the effects of ashwagandha in patients with a low sperm count (known as oligospermia), a total of 46 male patients were randomized either to treatment with KSM-66 Ashwagandha or placebo for 90 days [30]. At the end of the study, participants given KSM-66 ashwagandha showed a 167% increase in sperm count, a 53% increase in semen volume, and a 57% increase in sperm motility relative to baseline. In comparison, only minimal changes were seen in the placebo group. Further, a greater improvement in hormone levels was seen with KSM-66 ashwagandha. In other words, ashwagandha is likely to be very effective in treating oligospermia, which is a leading cause of male infertility. Similarly, a meta-analysis showed that ashwagandha significantly improved sperm concentration and sperm motility even in men with normal sperm parameters, without any adverse effects [31]. Ashwagandha has also been shown to enhance sexual function in women. At the Trupti Hospital and Santati Fertility Center located near Mumbai in India, 50 women were randomized to either ashwagandha treatment or placebo (300 mg twice daily) for 8 weeks [32]. In this study, ashwagandha supplementation was shown to lead to significantly higher scores in multiple markers of sexual desire and function.   But Is Ashwagandha Safe? Ashwagandha root powder has been used in Ayurvedic medicine for centuries, and it is believed to be completely safe and free of any toxicity. Extracts of ashwagandha made using alcohol and water will likely contain higher doses of its natural ingredients, relative to raw powder. So far animal studies with such extracts have shown no evidence of toxicity, even at relatively high doses [33]. However, it is always advisable to take an herbal supplement only after consulting your healthcare provider, especially if you have any ongoing health conditions or if you're pregnant or breastfeeding.   Organixx Turmeric 3D Contains KSM-66 Ashwagandha The Organixx Turmeric 3D formula has always contained ashwagandha extract. As part of our commitment to seeking out the cleanest and most effective supplement ingredients, we upgraded to KSM-66 Ashwagandha in 2019 – the most clinically studied ashwagandha on the market. KSM-66 is a full-spectrum extract produced using a unique proprietary extraction process, based on “Green Chemistry” principles, without using alcohol or any other chemical solvent.   Resources: [1] An Overview on Ashwagandha: A Rasayana (Rejuvenator) of Ayurveda. [2] Scientific basis for the use of Indian ayurvedic medicinal plants in the treatment of neurodegenerative disorders: ashwagandha. [3] Scientific Basis for the Therapeutic Use of Withania somnifera (Ashwagandha): A Review. [4] Anti‐stress activity of sitoindosides VII and VIII, new acylsterylglucosides from Withania somnifera. [5] A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults. [6] KSM-66 Ashwagandha Documentary [7] Society for Endocrinology: You and Your Hormones – Cortisol. [8] An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study. [9] Body Weight Management in Adults Under Chronic Stress Through Treatment With Ashwagandha Root Extract: A Double-Blind, Randomized, Placebo-Controlled Trial. [10] Withaferin A Protects Against High-Fat Diet-Induced Obesity Via Attenuation of Oxidative Stress, Inflammation, and Insulin Resistance. [11] Treatment of osteoarthritis with a herbomineral formulation: a double-blind, placebo-controlled, cross-over study. [12] Efficacy & safety evaluation of Ayurvedic treatment (Ashwagandha powder & Sidh Makardhwaj) in rheumatoid arthritis patients: a pilot prospective study. [13] The relationship between chondroprotective and antiinflammatory effects of Withania somnifera root and glucosamine sulphate on human osteoarthritic cartilage in vitro. [14] Efficacy of Ashwagandha (Withania somnifera [L.] Dunal) in improving cardiorespiratory endurance in healthy athletic adults. [15] Examining the effect of Withania somnifera supplementation on muscle strength and recovery: a randomized controlled trial. [16] Effects of an Aqueous Extract of Withania somnifera on Strength Training Adaptations and Recovery: The STAR Trial. [17] In vivo effects of Ashwagandha (Withania somnifera) extract on the activation of lymphocytes. [18] In vivo enhancement of natural killer cell activity through tea fortified with Ayurvedic herbs. [19] In vivo, Extract from Withania somnifera Root Ameliorates Arthritis via Regulation of Key Immune Mediators of Inflammation in Experimental Model of Arthritis. [20] Effects of Ashwagandha (roots of Withania somnifera) on neurodegenerative diseases. [21] Neuritic regeneration and synaptic reconstruction induced by withanolide A. [22] Combinations of Ashwagandha leaf extracts protect brain-derived cells against oxidative stress and induce differentiation. [23] Efficacy and Safety of Ashwagandha (Withania somnifera (L.) Dunal) Root Extract in Improving Memory and Cognitive Functions. [24] Medicinal Plants from Near East for Cancer Therapy. [25] Withaferin A: From ayurvedic folk medicine to preclinical anti-cancer drug. [26] Identification of Withaferin A as a Potential Candidate for Anti-Cancer Therapy in Non-Small Cell Lung Cancer. [27] Withaferin A inhibits expression of ataxia telangiectasia and Rad3-related kinase and enhances sensitivity of human breast cancer cells to cisplatin. [28] Subcritical water extraction of withanosides and withanolides from ashwagandha (Withania somnifera L) and their biological activities. [29] Cytotoxic Withanolides from the Roots of Indian Ginseng (Withania somnifera). [30] Clinical Evaluation of the Spermatogenic Activity of the Root Extract of Ashwagandha (Withania somnifera) in Oligospermic Males: A Pilot Study. [31] Withania somnifera (Indian ginseng) in male infertility: An evidence-based systematic review and meta-analysis. [32] Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Improving Sexual Function in Women: A Pilot Study. [33] Safety assessment of Withania somnifera extract standardized for Withaferin A: Acute and sub-acute toxicity study. KSM-66 Ashwagandha: A Superhero Herb for Body & Brain

In this issue, we explore the challenges associated with Schedule I therapeutic development. Click here to download a PDF, readable version of Issue 19: https://www.altasciences.com/sites/default/files/2022-03/The%20Altascientist_issue%2019_CNS%20Hallucinogens_v4.pdf Schedule I, or Class I (CI) drugs are currently restricted to research in the U.S., meaning that they are not approved for medical use, and are deemed at highest risk for abuse. Recent research on psychedelics and entactogens, both of which are Schedule I, is beginning to demonstrate potential therapeutic effects of these drugs for various medical indications. Approvals of such drugs for medical or therapeutic use will inevitably result in the rescheduling of these drugs from their current CI status. CHAPTERS: - 0:00 — Section 1: Introduction - 4:40 — Section 2: Research Site Requirements Associated with Development of Schedule 1 Drugs for Therapeutic Use - 8:01 — Section 3: Required Preclinical Studies - 10:30 — Section 4: Formulation, Manufacturing, and Analytical Considerations - 13:02 — Section 5: Required Clinical Studies - 18:27 — Section 6: Specialized Clinical Assessments - 20:19 — Section 7: Conclusion About Altasciences: Altasciences is an integrated drug development solution company offering pharmaceutical and biotechnology companies a proven, flexible approach to preclinical and clinical pharmacology studies, including formulation, manufacturing, and analytical services. For over 25 years, Altasciences has been partnering with sponsors to help support educated, faster, and more complete early drug development decisions. Altasciences' integrated, full-service solutions include preclinical safety testing, clinical pharmacology and proof of concept, bioanalysis, program management, medical writing, biostatistics, clinical monitoring, and data management, all customizable to specific sponsor requirements. Altasciences helps sponsors get better drugs to the people who need them, faster.

Dr. Elena Gross is a neuroscientist with a PhD in clinical research (specifically Ketosis in migraine prevention). She is also the CEO & founder of KetoSwiss. KetoSwiss develops and markets high quality exogenous ketone body therapeutics for use in disease prevention and treatment of specifically neurological diseases.KetoSwiss-  https://www.keto.swissYou can find Dr. Elena Gross on:Twitter - https://twitter.com/drelenagrossInstagram - https://www.instagram.com/drelenagross/Youtube - https://www.youtube.com/c/DrElenaGross

Stigma about psychedelics remains a problem and can cause harm when psychedelic users encounter judgment or other negative consequences in social contexts. Rooted in decades of misinformation and the failed war on drugs, there is a need for greater public education about the actual risks and benefits of psychedelics. In this episode we discuss a recent study that surveyed psychologists' attitudes about the use of psychedelics and discuss findings that demonstrate evidence of stigma. We discuss our personal experiences of stigma and how cultural and other identities can impact one's readiness to be assertive when encountering stigma in professional contexts. For more information about the study that was mentioned see: https://pubmed.ncbi.nlm.nih.gov/34468293/ (Attitudes and Beliefs about the Therapeutic Use of Psychedelic Drugs among Psychologists in the United States)

Today Joyce is talking with three canna-nurse practitioners based in Massachusetts, Julie Battel, Caitlin Bernhard and Marissa Fratoni. They are all health care providers who are using their skills, knowledge and networks to heal and to educate us at Azalla Wellness and Azalla Education. Julie, Caitlin and Marissa bring their decades of combined professional experience as practicing cannabis nurses and in the health and wellness industries to Azalla to provided unparalleled learning opportunities to Massachusetts Adult Use and Medical Use programs licensees. On today's show they share their experience and vision of a future working with cannabis industry and healthcare professionals, patients and the community-at-large to provide evidence-based educational experience centered on the Endocannabinoid System and cannabis.Thank you Dr. Bridgett Williams and the anthology she has put together, Courage in Cannabis, for supporting today's show. And Joyce gives a shout out to Massachusetts MCR Labs for putting together The Cannabis Review, a collection of scientific studies on cannabinoids and terpenes, arranged to help us identify and understand the unique potential of cannabis-based treatment. Topics Discussed(1:20) Trust(1:50) Ellen Rosenfeld and CommCan Dispensary(2:54) MCR Labs and the The Cannabis Review(3:50) Dr. Bridget Williams and Courage in Cannabis(4:20) Marissa Fratoni(5:35) Caitlin Bernhard(6:11) Julie Battel(6:31) American Cannabis Nurses Association(6:50) Green Networks Providers(10:05) Cannabinoids vs. Cannabis(12:50) Azalla Wellness and Education(13:41) Looking for Education(15:41) Nurses and Education(17:08) Canna Nurses(20:00) Aids and Cannabis, Home Baked (20:45) Cannabis Health Equity and Dr. Rachel Knox(21:30) ACHEM and Social Justice(23:50) Massachusetts and Social Equity(24:58) Responsible Vendor Training(26:30) Thank You Courage in Cannabis(27:55) Dr. Erik Brown Oklahoma Pharmacist(34:21) Illume Cannabis Wellness(34:37) Azalla Education(35:45) New York Cannabis(36:40) Application Process(38:31) Therapeutic Use(39:55) Connect with Caitlin Bernhard(40:20) Connect with Julie Battel(40:50) Connect with Marissa Fratoni and Holistic Nurse MamaThe Canna Mom Show wants to thank:Josh Lamkin and Bella Jaffe for writing and performing TCMS theme music