Podcasts about accessed february

Episode Summary: In recognition of National DNA Day, April 25, 2024, Dr. Mary Weissman, Miss Courtney Harmon, and Dr. Becky Winslow discuss clinical pharmacogenomics resources, what pharmacogenomics information they provide, and how to navigate and utilize the pharmacogenomics information to answer a prescriber's clinical question about pharmacogenomics' relationship to an adverse drug event.  Listeners interested in learning a step-wise approach to using the Food and Drug Administration's (FDA's) Table of Pharmacogenetics Associations and the FDA Table of Pharmacogenomic Biomarkers in Drug Labeling, the Clinical Pharmacogenetics Implementation Consortium's (CPIC's) database, and the Pharmacogenomics Knowledgebase (PharmGKB) to demystify pharmacogenomics' role in adverse drug events will not want to miss this Precision Health and PGx Podcast episode.  Biographies: Before founding inGENEious RX Incorporated, a boutique pharmacogenomics consulting firm, Dr. Winslow directed pharmacy business operations and clinical pharmacy programs in retail, hospital, long-term care, and public health pharmacies for Walmart Stores, Community Health Systems, Neil Medical Group, and the North Carolina Department of Health and Human Services. Since founding inGENEious RX over ten years ago, Dr. Winslow has worked with numerous distinguished vendors in the pharmacogenomics industry to reduce barriers holding pharmacogenomics back from becoming a standard of care including Translational Software, Admera Health, Genemarkers, National Association of Chain Drug Stores, Acutis Diagnostics, Kentucky Teachers' Retirement System, and GenXys.  A sought-after pharmacogenomics subject matter expert, Dr. Winslow, is an authority in pharmacogenomics access and reimbursement and specializes in business strategy consulting for pharmacogenomics stakeholders.   Dr. Mary Weissman is a pharmacogenomics science, clinical utility and reimbursement expert and inGENEious RX Incorporated team member.  After earning her PharmD from the Arnold and Marie Schwartz College of Pharmacy, Dr. Weissman completed a two-year pharmacogenomics fellowship with a clinical diagnostic lab. Upon completing her academic training in pharmacology and pharmacogenomics, Dr. Weissman embarked on a journey to apply her expertise in clinical diagnostic laboratories and has held several key scientific and clinical roles in pharmacogenomics laboratories. Through informative presentations, training sessions, papers, and webinars, she has helped clarify pharmacogenomics' complexities and highlight its potential to revolutionize medication management strategies for pharmacogenomics' stakeholders. Miss Courtney Harmon is graduating from Manchester University's Pharmacy and Pharmacogenomics programs in 2024.  She serves as a P4 liaison for Manchester University's chapter of Industry Pharmacists Organization (IPhO) and she is interested in pursuing a career in industry pharmacy. She has worked for Walgreens pharmacy for the last eight years.  References: 1. Table of pharmacogenomic biomarkers in drug labeling. U.S. Food and Drug Administration. Published August 10, 2023. Accessed February 1, 2024. https://www.fda.gov/drugs/science-and-research-drugs/table-pharmacogenomic-biomarkers-drug-labeling  2. Table of pharmacogenetic associations. U.S. Food and Drug Administration. Published October 26, 2022. Accessed February 1, 2024. https://www.fda.gov/medical-devices/precision-medicine/table-pharmacogenetic-associations  3. CPIC. Cpicpgx.org. Accessed February 1, 2024. https://cpicpgx.org  4. PharmGKB. PharmGKB. Accessed February 1, 2024. https://www.pharmgkb.org Keywords: #pharmacogenomics #ingeneiousrx #PGx #pharmacists #precisionhealthandpgxpodcast #pharmacypodcastnetwork #pharmacogenetics #genetics #sources #resources #FDA #CPIC #PharmGKB

Episode Summary: In recognition of National DNA Day, April 25, 2024, Dr. Mary Weissman, Miss Courtney Harmon, and Dr. Becky Winslow discuss clinical pharmacogenomics resources, what pharmacogenomics information they provide, and how to navigate and utilize the pharmacogenomics information to answer a prescriber's clinical question about pharmacogenomics' relationship to an adverse drug event.  Listeners interested in learning a step-wise approach to using the Food and Drug Administration's (FDA's) Table of Pharmacogenetics Associations and the FDA Table of Pharmacogenomic Biomarkers in Drug Labeling, the Clinical Pharmacogenetics Implementation Consortium's (CPIC's) database, and the Pharmacogenomics Knowledgebase (PharmGKB) to demystify pharmacogenomics' role in adverse drug events will not want to miss this Precision Health and PGx Podcast episode.  Biographies: Before founding inGENEious RX Incorporated, a boutique pharmacogenomics consulting firm, Dr. Winslow directed pharmacy business operations and clinical pharmacy programs in retail, hospital, long-term care, and public health pharmacies for Walmart Stores, Community Health Systems, Neil Medical Group, and the North Carolina Department of Health and Human Services. Since founding inGENEious RX over ten years ago, Dr. Winslow has worked with numerous distinguished vendors in the pharmacogenomics industry to reduce barriers holding pharmacogenomics back from becoming a standard of care including Translational Software, Admera Health, Genemarkers, National Association of Chain Drug Stores, Acutis Diagnostics, Kentucky Teachers' Retirement System, and GenXys.  A sought-after pharmacogenomics subject matter expert, Dr. Winslow, is an authority in pharmacogenomics access and reimbursement and specializes in business strategy consulting for pharmacogenomics stakeholders.   Dr. Mary Weissman is a pharmacogenomics science, clinical utility and reimbursement expert and inGENEious RX Incorporated team member.  After earning her PharmD from the Arnold and Marie Schwartz College of Pharmacy, Dr. Weissman completed a two-year pharmacogenomics fellowship with a clinical diagnostic lab. Upon completing her academic training in pharmacology and pharmacogenomics, Dr. Weissman embarked on a journey to apply her expertise in clinical diagnostic laboratories and has held several key scientific and clinical roles in pharmacogenomics laboratories. Through informative presentations, training sessions, papers, and webinars, she has helped clarify pharmacogenomics' complexities and highlight its potential to revolutionize medication management strategies for pharmacogenomics' stakeholders. Miss Courtney Harmon is graduating from Manchester University's Pharmacy and Pharmacogenomics programs in 2024.  She serves as a P4 liaison for Manchester University's chapter of Industry Pharmacists Organization (IPhO) and she is interested in pursuing a career in industry pharmacy. She has worked for Walgreens pharmacy for the last eight years.  References: 1. Table of pharmacogenomic biomarkers in drug labeling. U.S. Food and Drug Administration. Published August 10, 2023. Accessed February 1, 2024. https://www.fda.gov/drugs/science-and-research-drugs/table-pharmacogenomic-biomarkers-drug-labeling  2. Table of pharmacogenetic associations. U.S. Food and Drug Administration. Published October 26, 2022. Accessed February 1, 2024. https://www.fda.gov/medical-devices/precision-medicine/table-pharmacogenetic-associations  3. CPIC. Cpicpgx.org. Accessed February 1, 2024. https://cpicpgx.org  4. PharmGKB. PharmGKB. Accessed February 1, 2024. https://www.pharmgkb.org Keywords: #pharmacogenomics #ingeneiousrx #PGx #pharmacists #precisionhealthandpgxpodcast #pharmacypodcastnetwork #pharmacogenetics #genetics #sources #resources #FDA #CPIC #PharmGKB

Killers of the Flower Moon has brought the world's attention to one of the most vile murder cases in American history, and at the center of it all was Mollie Kyle-Burkhart. Mollie would have grown up in the traditional way of her Osage ancestors, but by the time she was an adult, her family was wealthy, and she lived in a big home with white servants and with a white husband. Mollie lost all of her family members during the reign of terror, and I can't imagine what it must have been like to go through something that horrible. On today's episode, we get into her story of resilience.  Bibliography Osage Nation. “About.” Accessed February 25, 2024. https://www.osagefoundation.org/about. Blakemore, Erin. “Erin Blakemore.” National Geographic, September 15, 2023. https://www.nationalgeographic.com/history/article/osage-murders-killers-of-the-flower-moon. Contributors to Wikimedia projects. “Ernest Burkhart.” Wikipedia, February 24, 2024. https://en.wikipedia.org/wiki/Ernest_Burkhart. ———. “Mollie Kyle.” Wikipedia, February 6, 2024. https://en.wikipedia.org/wiki/Mollie_Kyle. ———. “Osage Nation.” Wikipedia, February 23, 2024. https://en.wikipedia.org/wiki/Osage_Nation. ———. “William King Hale.” Wikipedia, February 19, 2024. https://en.wikipedia.org/wiki/William_King_Hale. Evans, Elinor. “Who Was Mollie Burkhart in Killers of the Flower Moon?” HistoryExtra, October 19, 2023. https://www.historyextra.com/period/20th-century/mollie-burkhart-who-killers-flower-moon/. Grann, David. Killers of the Flower Moon: The Osage Murders and the Birth of the FBI. Vintage, 2018. ———. “The Rare Archival Photos Behind ‘Killers of the Flower Moon.'” Atlas Obscura, May 18, 2017. https://www.atlasobscura.com/articles/osage-murders-photos-killers-of-flower-moon. Hemenway, Megan. “What Happened To Mollie & Ernest's Children After Killers Of The Flower Moon.” Screen Rant, October 26, 2023. https://screenrant.com/killers-flower-moon-mollie-ernest-children-what-happened/. Sam Noble Museum - The Sam Noble Museum at The University of Oklahoma inspires minds to understand the world through collection-based research, interpretation, and education. “History Behind A Giving Heritage - Sam Noble Museum,” October 1, 2019. https://samnoblemuseum.ou.edu/history-behind-osage-weddings-exhibit/. Kaplan, Anna. “What Happened To Mollie Burkhart, Subject of Killers Of The Flower Moon?” TODAY, January 11, 2024. https://www.today.com/popculture/movies/killers-of-the-flower-moon-what-happened-to-mollie-burkhart-now-rcna121685. McCluskey, Megan. “How Killers of the Flower Moon Captures the True Story of the Osage Murders.” Time: October 20, 2023. https://time.com/6325586/killers-of-the-flower-moon-true-story/. Montalvan, Karla. “The True Story of Osage Woman Mollie Burkhart.” Fierce, November 16, 2023. https://fiercebymitu.com/entertainment/mollie-burkhart-true-story-killers-of-the-flower-moon-osage/. Kansas Historical Society. “Osage - History and Culture From Early 20th Century to Present         - Kansapedia.” Accessed February 25, 2024. https://www.kshs.org/kansapedia/osage-history-and-culture-from-early-20th-century-to-present/19296. Oklahoma Historical Society | OHS. “Osage Murders.” Accessed February 25, 2024. https://www.okhistory.org/publications/enc/entry.php?entry=OS005. Quinn, Liam. “‘Killers of the Flower Moon True Story': All About the Real Events That Inspired the Martin Scorsese Film.” PEOPLE, October 20, 2023. https://people.com/killers-of-the-flower-moon-real-events-inspired-martin-scorsese-film-8364150. Romano, Aja. “Killers of the Flower Moon: What Is the True Story about the Osage Murders?” Vox, October 18, 2023. https://www.vox.com/culture/23920002/killers-flower-moon-true-story-osage-murders-reign-of-terror-mollie-burkhart-what-happened. Solly, Meilan. “The Real History Behind ‘Killers of the Flower Moon.'” Smithsonian Magazine, October 18, 2023. https://www.smithsonianmag.com/history/the-real-history-behind-killers-of-the-flower-moon-180983086/. World, Lenzy Krehbiel-Burton Tulsa. “Following the Headrights: Mollie Burkhart's Many Connections to the Osage Reign of Terror.” Tulsa World, October 4, 2023. https://tulsaworld.com/news/local/indigenous/following-the-headrights-mollie-burkharts-many-connections-to-the-osage-reign-of-terror/article_de635c84-5268-11ee-abe5-8b306bd2c14c.html.  

Do you know someone who might have a manipulative personality? What does it mean to be manipulative? Manipulation involves the use of deception or underhand methods to achieve personal aims. Manipulative people love to control, change, and warp the behaviors or perceptions of others. Do you anyone in mind who you think people be a manipulative person, but you aren't sure? To help you with that, let's go through some of the signs of a manipulative personality. Did you know that there are different types of manipulation? To find out more, watch this video: https://youtu.be/j5AOp93S1F4 Credits Writer: Julian Heng Script Editor: Rida Batool & Kelly Soong VO: Amanda Silvera Storyboarder: Yi Lin Animator: Anthony Shek YouTube Manager: Cindy Cheong References “9 Classic Traits of Manipulative People.” Psychology Today. Sussex Publishers. Accessed February 12, 2020. www.psychologytoday.com/sg/blog/in-flux/201610/9-classic-traits-manipulative-people. GoodTherapy. 2020. “Manipulation”. Goodtherapy.Org Therapy Blog. www.goodtherapy.org/blog/psychpedia/manipulation. Lancer, Darlene. 2020. “How To Spot Manipulation”. Psych Central. www.psychcentral.com/lib/how-to-spot-manipulation/. Do you have any personal stories or video requests that you would like to share with us? If so, email us at editorial@psych2go.net

Sabrina & Corinne from Two Girls One Ghost join us on this week's episode to talk about the dark histories behind childhood nursery rhymes. Fresh off of our ghost hunting experience at the Lizzie Borden house, we talk about the childhood rhyme and where it went wrong, as well as talk about others that SEEMED so innocent! Don't forget to check the episode on the Two Girls One Ghost feed where we talk about our ghost hunting experiences! It was WILD! Thank you to the wonderful Dave White of Bring me the Axe Podcast for research!ReferencesBurton-Hill, Clemency. 2015. The dark side of nursery rhymes. June 10. Accessed February 6, 2024. https://www.bbc.com/culture/article/20150610-the-dark-side-of-nursery-rhymes.Hazlett, Lisa A. 2009. "The use of British nursery rhymes and contemporary technology as venues for creating and expressing hidden literacies throughout time by children, adolescents, and adults." Forum on Public Policy: A Journal of the Oxford Round Table. Opie, Iona, and Peter Opie. 1952. The Oxofrd Dictionary of Nursery Rhymes. Oxford, UK: Oxford University Press.Roberts, Chris. 2005. Heavy Words Lightly Thrown: The Reason Behind the Rhyme. Sheridan, WY: Gotham Books.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Episode 163: Vascular Dementia      Future Dr. Ruby explains gives a definition of vascular dementia and concisely explains the pathophysiology and presentation of this disease. Dr. Arreaza reminds us of the importance of treating diabetes to prevent dementia.  Written by Carmen Ruby, MSIV, Ross University School of Medicine. Editing and comments by Hector Arreaza, MD. You are listening to Rio Bravo qWeek Podcast, your weekly dose of knowledge brought to you by the Rio Bravo Family Medicine Residency Program from Bakersfield, California, a UCLA-affiliated program sponsored by Clinica Sierra Vista, Let Us Be Your Healthcare Home. This podcast was created for educational purposes only. Visit your primary care provider for additional medical advice.What is vascular dementia?Vascular dementia is a condition that arises due to damage to blood vessels that reduce or block blood flow to the brain. A stroke can block an artery and result in various symptoms, such as changes in memory, thinking, or movement. Other conditions like high blood pressure or diabetes can also damage blood vessels and lead to memory or thinking problems over time.Vascular dementia (VaD) is a type of dementia that slowly worsens cognitive functions and is thought to be caused by vascular disease within the brain. Patients with VaD often exhibit symptoms similar to Alzheimer's disease (AD) patients. However, the changes in the brain are not due to Alzheimer's disease pathology (amyloid plaques and neurofibrillary tangles) but due to a chronic reduction in blood flow to the brain, eventually leading to dementia. Alzheimer's disease pathophysiology is very complex, and studies have shown that patients with AD can experience simultaneously several vascular issues that can affect cognitive function. For example, patients with AD may experience mini-strokes and have a reduction of the flow of oxygen and nutrients to the brain tissue. So, AD can be worsened by vascular factors as well, but the vascular factors are not the main problem in AD.Clinically, patients with VaD can appear very similar to those with AD, which makes it difficult to distinguish between the two diseases. Nevertheless, some clinical symptoms and brain imaging findings suggest that vascular disease is contributing to, if not entirely explaining, a patient's cognitive impairment.Epidemiology.In the US, VaD is the 2nd most common type of dementia (15-20% of cases). Prevalence increases with age (∼ 1–4% in patients ≥ 65 years.) People affected by vascular dementia typically start experiencing symptoms after age 65, although the risk is significantly higher for people in their 80s and 90s.EtiologyVaD may occur as a result of prolonged and severe cerebral ischemia of any etiology, primarily:Large artery occlusion (usually cortical ischemia) *Acute*Lacunar stroke (small vessel occlusion resulting in subcortical ischemia) *Acute/Subacute**Chronic* subcortical ischemiaRisk factors:Advanced ageHistory of strokeUnderlying conditions associated with cardiovascular disease:Chronic hypertensionDiabetesDyslipidemiaObesitySmokingClinical Features:Symptoms depend on the location of ischemic events and, therefore, vary widely amongst individuals, but a progressive impairment of daily life is common. Because of the diverse clinical picture, the term "vascular cognitive impairment" is gaining popularity over Vascular Dementia.Dementia due to small vessel disease:Symptoms tend to progress gradually or in a stepwise fashion and comparatively slower than in multi-infarct dementia.Generally associated with signs of subcortical pathology:Dementia due to large vessel disease Usually, sudden onsetMulti-infarct dementia: typically, stepwise deterioration Generally associated with signs of cortical pathology:Early symptomsReduced executive functioningLoss of visuospatial abilitiesConfusion ApathyMotor disorders (e.g., gait disturbance, urinary incontinence)Later symptomsImpaired memoryFurther cognitive decline: loss of judgment, disorientationMood disorders (e.g., euphoria, depression)Behavioral changes (e.g., aggressiveness)Advanced stages: further motor deterioration: dysphagia, dysarthriaDementia due to large vessel disease Usually, sudden onsetMulti-infarct dementia: typically, stepwise deterioration Generally associated with signs of cortical pathology:Cognitive impairment in combination with asymmetric or focal deficits (e.g., unilateral visual field defects, hemiparesis, Babinski reflex present)Overall, the symptoms vary depending on which areas of the brain are affected.Management and TreatmentThere is hope when it comes to managing the symptoms of vascular dementia. Although there is no cure for the condition, there are medications available that can help make life easier for those living with it. Additionally, there are drugs commonly used to treat memory issues in Alzheimer's disease that may be effective for individuals with vascular dementia. Sometimes, people with vascular dementia may experience mood changes, such as depression or irritability. These changes can be managed with medications used for depression or anxiety.Vascular risk modification: If your patient is experiencing cognitive impairment and has clinical or radiologic evidence of cerebrovascular pathology, getting screened for vascular risk factors, especially hypertension, is essential. Treatment can help prevent dementia, but it may not be as effective in reversing it. Statins are given after a stroke regardless of lipid levels.Antithrombotic therapy: For patients with vascular dementia who have had a clinical ischemic stroke or transient ischemic attack, they must receive the appropriate antithrombotic therapy based on the specific stroke subtype to help prevent any future ischemic strokes.When considering antiplatelet therapy for patients with vascular dementia who have not had a clinical ischemic stroke or TIA, it is important to make an individualized decision. For instance, we may prescribe aspirin at a dosage of 50-100 mg daily for patients with an infarction seen on brain imaging but not for those with only white matter lesions.Cholinesterase inhibitor therapy: It is recommended to start cholinesterase inhibitor therapy, such as donepezil or galantamine, for patients with vascular dementia who have a gradual cognitive decline that is not a direct result of a stroke. The evidence suggests that this treatment may offer a small cognitive benefit, but the clinical significance is unclear. Experts do not recommend cholinesterase inhibitors for patients with dementia diagnosed after a stroke if there is no gradual cognitive decline.Antipsychotics: We can briefly mention antipsychotics. They may be used but we have to remember they may increase mortality in the elderly, and the patient and family must be aware of this risk. Some examples are risperidone, quetiapine, and olanzapine, use them cautiously. Let's talk beyond medications, what other treatments can we offer? Non-pharmacologic options: In addition to medications, there are various ways to help a person with vascular dementia. Research has shown that physical exercise, sleep hygiene, and maintaining a healthy weight can not only enhance brain health but also reduce the risk of heart problems, stroke, and other diseases that affect blood vessels. Patients must be encouraged to eat a balanced diet, get enough sleep,limit alcohol intake, and encouraged to quit smoking, as these are other crucial ways to promote good brain health and reduce the risk of heart disease. Additionally, comorbid conditions such as diabetes, high blood pressure, or high cholesterol, must be treated, because they affect brain function and quality of life overall.It is essential to understand that emotional outbursts and personality changes can be caused by underlying brain disease and are not always intentional responses or reactions. When behavior problems overwhelm an individual, their family members, or friends, it is critical to seek support. Patient and caregiver support groups are helpful, offering a space to vent, grieve, and gain practical advice from others experiencing similar challenges. Exploring other sources of support, such as adult day programs, can also benefit caregivers and individuals affected by vascular dementia. Conclusion: Now we conclude episode number 163, “Vascular dementia basics.” Future Dr. Ruby explained that vascular dementia is mainly caused by an impaired circulation of blood and oxygen to certain areas in the brain. This can be a result of large or small vessel disease. Dr. Arreaza reminded us of the importance of treating diabetes as a way to prevent dementia. This week we thank Hector Arreaza and Carmen Ruby. Audio editing by Adrianne Silva.Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week! _____________________References:Smith, MD EE, Wright, MD, MS CB. Treatment of Vascular Cognitive Impairment and Dementia. Wilterdink, MD JL, ed. UpToDate. Published online May 24, 2022. Accessed February 27, 2024. https://www.uptodate.comVascular Dementia. Memory and Aging Center. Published 2020. https://memory.ucsf.edu/dementia/vascular-dementiaVascular dementia. AMBOSS. Published online June 29, 2023. Accessed February 28, 2024. https://www.amboss.com/usWhat Happens to the Brain in Alzheimer's Disease? National Institute on Aging, https://www.nia.nih.gov/health/alzheimers-causes-and-risk-factors/what-happens-brain-alzheimers-disease. Royalty-free music used for this episode: Space Orbit by Scott Holmes, downloaded on July 20, 2022 from https://freemusicarchive.org/music/Scott_Holmes/. 

On this episode, experts discuss the role of celebrity endorsements and trusted local figures in addressing vaccine hesitancy. Experts commented on studies examining how peer influencers and endorsements from figures like Dr. Fauci can increase vaccine acceptance by making the issues more relatable. However, they also noted the need to understand different factors contributing to hesitancy as well as ensuring endorsements match the right target audience and local context to be most effective. The podcast explored both the potential and limitations of celebrity marketing in vaccine promotion and uptake. Experts Include: Sean Young, PhD, executive director of the University of California Institute for Prediction Technology; Alfred L'Altrelli, PharmD, CFMC, MBA, the senior director of pharmacy at UPMC Presbyterian-Shadyside; and Troy Trygstad, PharmD, PhD, MBA, the executive director of CPESN USA. Key Takeaways 1. The podcast discussed vaccine hesitancy and how celebrity endorsements can be used to address it. Experts commented on factors like personal beliefs, social networks, and online misinformation that contribute to hesitancy. 2. Pharmacists noted that conversations with patients have shifted from vaccine development to side effects and efficacy as awareness has increased. Misinformation remains a challenge. 3. Studies found that peer-led online communities and celebrity endorsements, like from Dr. Fauci, can increase vaccine acceptance and confidence. Experts emphasized matching the right celebrity to the target audience. 4. While celebrity endorsements may not directly drive people to pharmacies, they can make vaccination more relatable and impact attitudes. Local media personalities were suggested as alternative endorsers. 5. The podcast explored both the potential benefits but also limitations of celebrity endorsements in influencing public health decisions around vaccines. Understanding audience trust was a key consideration. References 1. Gallagher A. Celebrities Don't Persuade Patients to Get Vaccinated; Pharmacists Do. Pharmacy Times. January 18, 2024. Accessed February 15, 2024. https://www.pharmacytimes.com/view/celebrities-don-t-persuade-patients-to-get-vaccinated-pharmacists-do 2. Bokemper SE, Huber GA, Gerber AS, James EK, Omer SB. Timing of COVID-19 vaccine approval and endorsement by public figures. Vaccine. 2021;39(5):825-829. doi:10.1016/j.vaccine.2020.12.048

In a conversation with CancerNetwork®, Robert A. Winn, MD, spoke about current obstacles in achieving equitable care for patients with cancer and discussed how initiatives from community health centers and federal bodies alike may help increase access to anti-cancer therapy. Winn, director and Lipman Chair in Oncology at Virginia Commonwealth University (VCU) Massey Comprehensive Cancer Center, senior associate for Cancer Innovation, and professor of pulmonary disease and critical cancer medicine at VCU School of Medicine, began the discussion by defining health equity as a principle. By eliminating disparities that impact access to treatment for certain populations, it may be possible for all patients to receive the same kind of care and potentially experience the same outcomes as part of an “even playing field.” According to Winn, initiatives that may promote health equity in oncology include the ruling from the Centers for Medicare & Medicaid Services (CMS) allowing for the reimbursing of navigation services to help patients and their families access treatment for cancer and other serious diseases.1 Although Winn said that the field was trending towards the goal of health equity, he stated that more progress was necessary for biomarker testing in lung cancer and other malignancies. Additionally, increasing access to new treatments, technologies, and screening mechanisms across different communities represented another challenge concerning progress.  Winn also spoke about educating others on cancer-related disparities, including his colleagues and other resourceful groups in cancer care. He detailed his experiences with working on the yearly American Association for Cancer Research (AACR) Cancer Disparities Progress Reports since the first was published in 2020, which he described as an element that he hopes will educate people and spread awareness. In addition to collaboration among professional bodies including the Association of American Cancer Institutes and the American Society of Clinical Oncology, Winn highlighted local efforts in spreading awareness and improving progress towards health equity. “By not sitting on our heels and waiting for the community to come to us, but by going out to the community and talking about the importance of screening, talking about the importance of finding a new drug and what that means, and talking about these new technologies, we've actually gotten a very robust group of community members who are actually by our sides and actually making other people aware out in the community,” Winn said regarding Facts & Faith Fridays, an initiative from Massey Comprehensive Cancer Center in collaboration with local faith-based leaders designed to spread awareness of anti-cancer treatment.2 “That has resulted in very positive outcomes for us.” References 1.        CMS finalizes physician payment rule that advances health equity. News release. Centers for Medicare & Medicaid Services. November 2, 2023. Accessed February 27, 2024. http://tinyurl.com/4p7dhr7h 2.        Facts & Faith Fridays. VCU Massey Comprehensive Cancer Center. Accessed February 27, 2024. http://tinyurl.com/5wetmdyz

On August 16, 1977, the nation was shocked when the evening headlines were sent out. Elvis Presley, the King of Rock and Roll was dead. What else was being reported on such a tragic day? SOURCES “Advertisement: RCA Televisions (Page 2).” The Winona Daily News (Winona, Minnesota), August 16, 1977. www.newspapers.com. Associated Press. “N. Y. Grand Jury Indicts Berkowitz in Slaying.” The Daily Pantagraph (Bloomington, Illinois), August 16, 1977. www.newspapers.com. “Biography.” Graceland. Accessed February 2, 2024. https://www.graceland.com/biography. Blanco, Juan Ignacio. “Herbert Lee Richardson: Murderpedia, the Encyclopedia of Murderers.” Herbert Lee Richardson | Murderpedia, the encyclopedia of murderers. Accessed February 5, 2024. https://murderpedia.org/male.R/r1/richardson-herbert.htm. “Bomb Kills Girl Here; Man Sought In Death.” The Dothan Eagle (Dothan, Alabama), August 16, 1977. www.newspapers.com. “David Berkowitz.” Wikipedia, February 1, 2024. https://en.wikipedia.org/wiki/David_Berkowitz. Ehrlich, Ken. “Portrait Is Saco Man's Hope for Elvis Meeting.” Journal Tribune (Biddeford, Maine), August 16, 1977. www.newspapers.com. “Elvis Presley Dies.” The San Francisco Examiner (San Francisco, California), August 16, 1977. www.newspapers.com. “Lost Graveyard Haunts Park Developer.” Tri-City Herald (Pasco, Washington), August 16, 1977. www.newspapers.com. “Old Almshouse Cemetery.” Rootsweb. Accessed February 2, 2024. https://sites.rootsweb.com/~paerie/cemeteries/almshouse.htm. “Richardson v. State.” Justia Law. Accessed February 5, 2024. https://law.justia.com/cases/alabama/court-of-appeals-criminal/1978/376-so-2d-205-0.html. Ripley's Believe It or Not!, Steph Distasio, and Colton Kruse. “Bizarre Elvis Facts That Will Leave You All Shook Up.” Ripley's Believe It or Not!, November 17, 2023. https://www.ripleys.com/weird-news/bizarre-elvis-facts/. “The Rise of the Son of Sam.” Psychology Today. Accessed February 2, 2024. https://www.psychologytoday.com/us/blog/wicked-deeds/202310/the-rise-of-the-son-of-sam. Whole. The Sons of Sam: A Descent Into Darkness 1, no. 1. Netflix, May 5, 2021. www.newspapers.com. SOUND SOURCES Al Jolson. “I'll Say She Does.” www.pixabay.com/music. Lucille Hegamin and The Dixie Daisies. “Cold Winter Blues.” www.pixabay.com/music. Sophie Tucker. “Reuben Rag.” www.pixabay.com/music.

After the 2024 Gastrointestinal Cancers Symposium, Jun Gong, MD, and Daneng Li, MD, sat down to discuss the most relevant trial data to have come from the conference. They convened for a live X Space hosted by CancerNetwork®. During the discussion, they covered different trials across the gastrointestinal space, which included those evaluating different disease states from hepatocellular carcinoma (HCC) to colorectal cancer (CRC), and those assessing circulating tumor DNA (ctDNA) dynamics. Gong, a hematologic oncologist focusing on gastrointestinal and genitourinary cancers at Cedars-Sinai Medical Center, and Li, an associate professor in the Department of Medical Oncology and Therapeutics Research at City of Hope, each gave their perspective on the clinical trial data and discussed if they had implemented any of these study treatments into clinical practice.  The studies they covered included:  1.        Phase 3 NETTER-2 Trial (NCT03972488)1: - Investigated lutetium Lu 177 dotatate (Lutathera) plus octreotide vs octreotide alone for advanced gastroenteropancreatic neuroendocrine tumors (GEP-NETs). - Lutetium Lu 177 significantly improved progression-free survival (PFS) and overall response rate (ORR) compared with octreotide alone. - The agent may be considered for patients with high-grade GEP-NETs who desire significant tumor shrinkage. 2.        Phase 3 EMERALD-1 Trial (NCT03778957)2: - Studied transarterial chemoembolization (TACE) plus durvalumab (Imfinzi) with or without bevacizumab (Avastin) for unresectable HCC. - Durvalumab/bevacizumab plus TACE improved PFS compared with placebo plus TACE. - TACE may be preferred over transarterial radioembolization (TARE) due to faster patient recovery. 3.        Phase 3 CheckMate-8HW Trial3: - Evaluated nivolumab (Opdivo) plus ipilimumab (Yervoy) vs chemotherapy for first-line treatment of microsatellite instability-high/mismatch repair deficient metastatic CRC. - Nivolumab/ipilimumab demonstrated superior PFS compared with chemotherapy. - Chemotherapy may no longer be the standard first-line treatment for this patient population. 4.        BESPOKE Study (NCT04264702)4: - Assessed the impact of minimal residual disease (MRD) detected by ctDNA on disease recurrence in patients with stage II and III CRC receiving adjuvant chemotherapy. - MRD positivity was associated with worse disease-free survival (DFS). - ctDNA clearance at 12 weeks indicated improved DFS.  5.        GALAXY Trial5: - ctDNA is a promising biomarker that can be used to predict recurrence in patients with CRC. - Patients with ctDNA-positive disease had a worse DFS than patients with ctDNA-negative disease. - This suggests that ctDNA may be useful for making treatment decisions, but more research is needed before it can be used in clinical practice. 6.        Phase 3 FRESCO-2 Trial (NCT04322539)6: - Fruquintinib (Fruzaqla) improved the quality of life in patients with metastatic CRC when combined with best supportive care and significantly improved quality-adjusted time without symptoms of disease or toxicity compared with placebo and best supportive care. - The study showed positive effects on PFS, response rate, disease control, and duration of response with the fruquintinib combination. - The findings from this trial supported the FDA approval of fruquintinib for metastatic CRC in November 2023.7 References 1.        Singh S, Halperin D, Myrehaug S, et al. [177Lu]Lu-DOTA-TATE in newly diagnosed patients with advanced grade 2 and grade 3, well-differentiated gastroenteropancreatic neuroendocrine tumors: primary analysis of the phase 3 randomized NETTER-2 study. J Clin Oncol. 2024(suppl 3):LBA588. doi:10.1200/JCO.2024.42.3_suppl.LBA588 2.        Lencioni R, Kudo M, Erinjeri J, et al. EMERALD-1: a phase 3, randomized, placebo-controlled study of transarterial chemoembolization combined with durvalumab with or without bevacizumab in participants with unresectable hepatocellular carcinoma eligible for embolization. J Clin Oncol. 2024;42(suppl 3):LBA432. doi.10.1200/JCO.2024.42.3_suppl.LBA432 3.        Andre T, Elez E, Van Cutsem E, et al. Nivolumab (NIVO) plus ipilimumab (IPI) vs chemotherapy (chemo) as first-line (1L) treatment for microsatellite instability-high/mismatch repair-deficient (MSI-H/dMMR) metastatic colorectal cancer (mCRC): First results of the CheckMate 8HW study. J Clin Oncol. 2024;42(suppl_3):LBA768. doi.10.1200/JCO.2024.42.3_suppl.LBA768 4.        Kasi P, Aushev V, Ensor J, et al. Circulating tumor DNA (ctDNA) for informing adjuvant chemotherapy (ACT) in stage II/III colorectal cancer (CRC): interim analysis of BESPOKE CRC study. J Clin Oncol. 2024;42 (suppl _3):9. doi:10.1200/JCO.2024.42.3_suppl.9 5.        Yukami H, Nakamura Y, Mishima S, et al. Circulating tumor DNA (ctDNA) dynamics in patients with colorectal cancer (CRC) with molecular residual disease: Updated analysis from GALAXY study in the CIRCULATE-JAPAN. J Clin Oncol. 2024;42(suppl_3):6. doi:10.1200/JCO.2024.42.3_suppl.6 6.        Stintzing S, Tabernero J, Satoh T, et al. Quality-adjusted time without symptoms of disease or toxicity (Q-TWiST) analysis of fruquintinib + best supportive care (BSC) compared with placebo + BSC in metastatic colorectal cancer (mCRC): results from the FRESCO-2 trial. J Clin Oncol. 2024;42(suppl 3):116. doi:10.1200/JCO.2024.42.3_suppl.116 7.        FDA approves fruquintinib in refractory metastatic colorectal cancer. FDA. News release. November 8, 2023. Accessed February 7, 2024. https://shorturl.at/isJW2

Welcome to this special episode of the NeurologyLive® Mind Moments® podcast. Tune in to hear leaders in neurology sound off on topics that impact your clinical practice. For major FDA decisions in the field of neurology, we release short special episodes to offer a snapshot of the news, including the main takeaways for the clinical community, as well as highlights of the efficacy and safety profile of the agent in question. In this episode, we're covering the recent approval of vamorolone (Agamree; Santhera Pharmaceuticals) oral suspension 40 mg/mL for the treatment of patients with Duchenne muscular dystrophy (DMD) aged 2 years and older. The therapy is set to be acquired by Catalyst Pharmaceuticals soon, and is a first-in-class dissociative steroid that aims to retain the anti-inflammatory activity of corticosteroids while decreasing the deleterious adverse events (AEs). We spoke with Barry J. Byrne, MD, PhD, professor and associate chair of pediatrics and director of the Powell Gene Therapy Center at the University of Florida, who discussed the recent FDA approval of Santhera Pharmaceuticals investigational agent vamorolone (now marketed as Agamree, and soon to be acquired by Catalyst Pharmaceuticals in North America), its potential to affect the treatment paradigm as a first-in-class dissociative steroid, and important efficacy and safety information from the phase 2b VISION-DMD study (NCT03439670). For more of NeurologyLive's coverage of vamorolone's approval, head here: FDA Approves Vamorolone as a Treatment for Duchenne Muscular Dystrophy Episode Breakdown: 0:30 – Vamorolone approved for Duchenne muscular dystrophy 2:20 – Barry J. Byrne, MD, PhD, on his immediate reaction 3:25 – Safety data on vamorolone 4:00 – Byrne on the importance of bone mineralization in DMD 5:10 – Phase 2b efficacy data from VISION-DMD 5:45 – Byrne with context on the efficacy data 7:05 – Byrne with context on the landscape of DMD therapeutic development and personalization approaches Thanks for listening to the NeurologyLive Mind Moments podcast. To support the show, be sure to rate, review, and subscribe wherever you listen to podcasts. For more neurology news and expert-driven content, visit neurologylive.com. REFERENCES 1. Catalyst Pharmaceuticals Reports FDA Approval of AGAMREE® (vamorolone) for Duchenne Muscular Dystrophy Granted to Santhera Pharmaceuticals. News release. Catalyst Pharmaceuticals. October 26, 2023. Accessed October 26, 2023. https://www.globenewswire.com/en/news-release/2023/10/26/2767947/13009/en/Catalyst-Pharmaceuticals-Reports-FDA-Approval-of-AGAMREE-vamorolone-for-Duchenne-Muscular-Dystrophy-Granted-to-Santhera-Pharmaceuticals.html 2. Santhera and ReveraGen announce positive and statistically highly significant topline results with vamorolone in pivotal VISION-DMD study. News release. Santhera. June 1, 2021. Accessed February 1, 2023. https://www.globenewswire.com/news-release/2021/06/01/2239124/0/en/Santhera-and-ReveraGen-Announce-Positive-and-Statistically-Highly-Significant-Topline-Results-with-Vamorolone-in-Pivotal-VISION-DMD-Study.html 3. Dang U, Guglieri M, Clemens PR, et al. Delayed start analysis of efficacy outcomes in placebo to vamorolone crossover participants in VBP15-004. Presented at MDA Clinical and Scientific Conference; March 13-16. Poster 89. 4. Muscular Dystrophy Association-Supported Drug AGAMREE® (vamorolone) Approved for the Treatment of Duchenne Muscular Dystrophy by the FDA. News release. MDA. October 26, 2023. Accessed October 26, 2023. https://www.mda.org/press-releases/mda-supported-drug-agamree-vamorolone-approved-for-the-treatment-of-duchenne-muscular-dystrophy-by-the-fda 5. Guglieri M, Clemens PR, Perlman SJ, et al. Efficacy and safety of vamorolone vs placebo and prednisone among boys with Duchenne muscular dystrophy: a randomized clinical trial. JAMA Neurol. Published online August 29, 2022. doi:10.1001/jamaneurol.2022.2480

Join Yvonne Brandenburg, RVT, VTS SAIM and Jordan Porter RVT, VTS SAIM as we talk WITH: Elycia Degenhardt about how multitasking can actually hinder our ability to be efficient and effective in our daily work. But don't fret, we also discuss ways to manage our time efficiently!     Resources We Mentioned in the Show   Mark G, Gudith D, Klocke U. The Cost of Interrupted Work: More Speed and Stress. CHI '08: Proceedings of the SIGCHI Conference on Human Factors in Computing Systems. 2008;107-110. Marois R, Ivanoff J. Capacity limits of information processing in the brain. TRENDS in Cognitive Sciences. 2005;9. 296-305 Multitasking: Switching costs. American Psychological Association. https://www.apa.org/research/action/multitask. Published March 20, 2006. Accessed February 4, 2021. O'Conaill B, Frohlich D. Timespace in the Workplace: Dealing With Interruptions. CHI ‘95 Mosaic of Creativity. 1995;262-263. To Multitask or Not to Multitask. University of Southern California. https://appliedpsychologydegree.usc.edu/blog/to-multitask-or-not-to-multitask/. Accessed February 2, 2021. Weinschenk S. The True Cost of Multitasking. Psychology Today. https://www.psychologytoday.com/us/blog/brain-wise/201209/the-true-cost-multi-tasking. Published September 18, 2012. Accessed February 2, 2021. The Multitasking Monster Article: https://www.petvetmagazine.com/multitasking-monster/  Thanks so much for tuning in. Join us again next week for another episode!  Want to earn some RACE approved CE credits for listening to the podcast? You can earn between 0.5-1.0  hour of RACE approved CE credit for each podcast episode you listen to.    Join the Internal Medicine For Vet Techs Membership to earn and keep track of your continuing education hours as you get your learn on!   Join now! http://internalmedicineforvettechsmembership.com/   Get Access to the Membership Site for your RACE approved CE certificates Sign up at https://internalmedicineforvettechsmembership.com  Get Access to the Technician Treasure Trove  Sign up at https://imfpp.org/treasuretrove    Thanks for listening!  – Yvonne and Jordan     

On December 15, 1996, Baltimore police discovered the body of twenty-three-year-old Kimberly Spicer buried under a trailer on the property of a pallet factory in the city's southwest side. Later that day, police arrested Joseph Methainy, a man who lived and worked at the factory where Spicer's body was discovered. It didn't take long for police to solidly connect Methainy to the murders of two additional Baltimore women as well. In his wild confessions he claimed massive victim numbers and even cannibalism. Thanks to Dave White for research assistance!ReferencesAssociated Press. 1997. "Man's trial in slaying of 2 women is postponed; change of venue sought." Baltimore Sun, July 8: 4B.—. 1996. "Accused killer called fun-loving." Daily Times, December 20: 2.—. 1997. "Mount Airy scientits finds where the bones are buried." Star-Democrat, February 5: 13.—. 1998. "Officials: Methainy attempted suicide ." Star-Democrat, March 24: 6.—. 1996. "'Practical joker' held in 3 slayings." The Capital, December 20: 14.—. 1997. "Suspected serial killer indicted." The Daily Times, January 29: 2.Hermann, Peter. 1996. "Suspect charged in 2 more slayings." Baltimore Sun, December 19: 25.—. 1996. "Suspect gives police details of 4 slayings." Baltimore Sun, December 21: 1A.—. 1996. "Suspect in slaying says he killed 2 others Police searches yield." Baltimore Sun, December 18.Higham, Scott. 1998. "Methainy found guilty of killing woman." Baltimore Sun, May 15: 8B.Hopper, Dale. 1997. "Murder suspect convicted of kidnapping, assault." Star-Democrat, November 18: 3.Investigation Discovery. 2016. Serial killer Joe 'The Cannibal' Methainy, served human burgers at his BBQ stand, dead in cell. December 19. Accessed February 27, 2023. https://www.investigationdiscovery.com/crimefeed/serial-killer/joe-the-cannibal-Methainy-the-serial-killer-with-a-penchant-for-human-flesh-burgers.Irwin, Richard. 1996. "2 men charged in woman's stabbing death." Baltimore Sun, December 16: 2B.Jacobson, Joan. 2000. "Court voids death verdict." Baltimore Sun, July 25: 11.—. 1998. "Killer given death penalty." Baltimore Sun, November 14: 1.—. 1998. "Methainy sentencing testimony begins." Baltimore Sun, November 10: 27.James, Michael. 1997. "As police sift claims, families seek solace." Baltimore Sun, January 13: 1.Methainy v. State of Maryland. 2000. 149 (Court of Appeals of Maryland, July 24).Pekkanen, Sarah. 1998. "Suspect's confession to killing played in court." Baltimore Sun, May 1: 1B.Penn, Ivan. 1997. "Slaying suspect on trial in attempted murder." Baltimore Sun, November 6: 11B.—. 1997. "Woman describes night of attack." Baltimore Sun, November 7: 7B.Prudente, Tim. 2017. "Convicted murderer dead in his cell." Baltimore Sun, August 8: A2.Shatzkin, Kate. 1997. "Death penalty to be sought in slayings of 2." Baltimore Sun, March 21.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Compared to Queen Liliuokalani, Queen Emma gets very little attention in the grand scheme of things. Like her cousin Lili, Emma was born into Hawaiian royalty, but she hardly could have conceived that she would not only be a popular consort but also have the chance to campaign to run the kingdom in her own name. Emma was fashionable, beautiful and a true jewel of the Hawaiian royal family. Come learn about her story on today's episode. Bibliography Bloks, Moniek. “Emma of Hawaii - A Beloved Queen (Part One).” History of Royal Women, February 27, 2019. https://www.historyofroyalwomen.com/emma-of-hawaii/emma-of-hawaii-a-beloved-queen-part-one/. ———. “Emma of Hawaii - A Beloved Queen (Part Two).” History of Royal Women, March 6, 2019. https://www.historyofroyalwomen.com/hawaii/emma-of-hawaii-a-beloved-queen-part-two/. Contributors to Wikimedia projects. “Albert Kamehameha.” Wikipedia, January 2, 2023. https://en.wikipedia.org/wiki/Albert_Kamehameha. ———. “Fanny Kekelaokalani.” Wikipedia, September 6, 2021. https://en.wikipedia.org/wiki/Fanny_Kekelaokalani. ———. “George Naea.” Wikipedia, July 11, 2022. https://en.wikipedia.org/wiki/George_Naea. ———. “Grace Kamaikui.” Wikipedia, August 31, 2022. https://en.wikipedia.org/wiki/Grace_Kamaikui. ———. “Kamehameha IV.” Wikipedia, January 12, 2023. https://en.wikipedia.org/wiki/Kamehameha_IV. ———. “Queen Emma of Hawaii.” Wikipedia, December 31, 2022. https://en.wikipedia.org/wiki/Queen_Emma_of_Hawaii. ———. “Thomas Charles Byde Rooke.” Wikipedia, November 14, 2021. https://en.wikipedia.org/wiki/Thomas_Charles_Byde_Rooke. Royal Family Hawaii. “Royal Family of Hawaii Official Website.” Accessed February 4, 2023. https://www.crownofhawaii.com/queen-emma-rs.

In this episode, GI specialist dietitian, Emily Manez, MS, RD, CNSC, shares her experience working as a dietitian in the world of solid organ transplant. She discusses the process of organ transplant from patient selection to discharge and highlights the important role a dietitian plays in promoting a successful outcome.    Show Notes:  Centers for Medicare & Medicaid Services (CMS), HHS. Medicare program; hospital conditions of participation: requirements for approval and re-approval of transplant centers to perform organ transplants. Final rule. Fed Regist. 2007;72(61):15197-15280.  Hayes D, Melicoff-Portillo E, Ziady AG. Selection of lung transplant candidates: A pediatric perspective on the International Society for Heart and Lung Transplantation consensus document. The Journal of Heart and Lung Transplantation. Published online February 2022. doi: http://bit.ly/3nhlJYq  OPTN: Organ Procurement and Transplantation Network. Member Evaluation Plan. Updated February 1, 2023.  Accessed February 24, 2023: https://bit.ly/40wbv58 

Easter marked the 60th anniversary of the disappearance of 22 year old Hannah Jane Rowell. Her estranged husband believed Jane abandoned the family to leave Baton Rouge, Louisiana and try to make it in Hollywood. Her distraught and protective brother vowed there was foul play.    Want more Southern Mysteries?  Hear the Southern Mysteries show archive of 60+ episodes along with Patron exclusive podcast, Audacious: Tales of American Crime and more when you become a patron of the show. You can immediately access exclusive content now at patreon.com/southernmysteries   Connect Website: southernmysteries.com Facebook: Southern Mysteries Podcast Twitter: @southernpod_ Instagram: @shannonballard_ Email: southernmysteriespodcast@gmail.com    Episode Sources Jane Clement Missing Since 1963. The Hammond Star, Bayou Justice. Accessed February 25, 2020. https://www.hammondstar.com/news/jane-clement-missing-since-1963/article_317d206e-c244-53a3-a061-6b13a44b0413.html Dental Chart of Missing Woman Studied. The Daily Iberian. December 10, 1963. https://www.newspapers.com/image/849587767/ Jane Rowell Clement. Doe Network. Accessed March 13, 2023. https://www.doenetwork.org/cases/1373dfla.html Jane Clement Rowell. The Charley Project. Accessed March 13, 2023. https://charleyproject.org/case/jane-rowell-clement Jane Clement missing since 1963. Bayou Justice. Accessed March 28, 2023. https://bayoujustice.com/2023/03/jane-clement-missing-since-1963-2/ Jane Rowell buried in concrete tomb. Bayou Justice. Accessed March 28, 2023. https://bayoujustice.com/2023/03/jane-rowell-buried-in-concrete-tomb/   Episode Music Not Alone by Lee Rosevere. Licensed under Creative Commons; Theme Song “Dark & Troubled” by Pantherburn. Special thanks to Phillip St Ours for permission for use

In this episode I cover the aftermath of the Spanish conquests of America and more specifically, the consequences the conquistadors faced after partaking in them. References 2019. Francisco Vázquez de Coronado - Facts, Routes & Wife - HISTORY. https://www.history.com/topics/exploration/francisco-vazquez-de-coronado. Ballesteros, Manuel. n.d. “Francisco Pizarro | Biography, Accomplishments, & Facts | Britannica.” Encyclopedia Britannica. Accessed February 27, 2023. https://www.britannica.com/biography/Francisco-Pizarro. “The Basque Juan de Garay: colonizer and conqueror, the search for the city of the Caesars and his tragic death.” 2022. Infobae. https://www.infobae.com/en/2022/03/21/the-basque-juan-de-garay-colonizer-and-conqueror-the-search-for-the-city-of-the-caesars-and-his-tragic-death/. Chasteen, John C. 2016. Born in Blood & Fire: A Concise History of Latin America. N.p.: W.W. Norton. Flint, Valerie I. n.d. “Christopher Columbus | Biography, Nationality, Voyages, Ships, Route, & Facts.” Encyclopedia Britannica. Accessed February 26, 2023. https://www.britannica.com/biography/Christopher-Columbus. “Gonzalo Jiménez de Quesada | Spanish conquistador | Britannica.” 2023. Encyclopedia Britannica. https://www.britannica.com/biography/Gonzalo-Jimenez-de-Quesada. “Guzmán, Nuño Beltrán de (c. 1485–1558).” n.d. Encyclopedia.com. Accessed February 26, 2023. https://www.encyclopedia.com/humanities/encyclopedias-almanacs-transcripts-and-maps/guzman-nuno-beltran-de-c-1485-1558. Innes, Hammond. 2023. “Hernan Cortes | Expeditions, Biography, & Facts | Britannica.” Encyclopedia Britannica. https://www.britannica.com/biography/Hernan-Cortes. “Juan Díaz de Solís | Spanish explorer | Britannica.” 2023. Encyclopedia Britannica. https://www.britannica.com/biography/Juan-Diaz-de-Solis. Mann, Charles C. 2012. 1493: Uncovering the New World Columbus Created. N.p.: Knopf Doubleday Publishing Group. “Olid, Cristóbal De (1488–1524).” n.d. Encyclopedia.com. Accessed February 26, 2023. https://www.encyclopedia.com/humanities/encyclopedias-almanacs-transcripts-and-maps/olid-cristobal-de-1488-1524. “Pedro de Alvarado | Biography & Facts | Britannica.” 2023. Encyclopedia Britannica. https://www.britannica.com/biography/Pedro-de-Alvarado. Todorov, Tzvetan. 1999. The conquest of America : the question of the other. Edited by Richard Howard. Translated by Richard Howard. N.p.: University of Oklahoma Press. --- Support this podcast: https://podcasters.spotify.com/pod/show/d-a-f-l-o-w/support

In December 1989, Judge Robert Vance was killed in his Alabama home when he opened a package that contained a mail bomb. Two days later Civil rights attorney Robert Robinson was killed in a separate explosion in Georgia. The investigation to find the person responsible for the attacks became one of the largest cases in FBI history.    Want more Southern Mysteries?  Hear the Southern Mysteries show archive of 60+ episodes along with Patron exclusive podcast, Audacious: Tales of American Crime and more when you become a patron of the show. You can immediately access exclusive content now at patreon.com/southernmysteries   Connect Website: southernmysteries.com Facebook: Southern Mysteries Podcast Twitter: @southernpod_ Instagram: @shannonballard_ Email: southernmysteriespodcast@gmail.com    Episode Sources Helen Vance is remembered as passionate about life, animal lover. AL.com. Accessed January 15, 2023. https://www.al.com/spotnews/2010/10/helen_vance_remembered_as_pass.html Family remembers Savannah attorney killed in 1989 bombing. WTOC.com. Accessed January 20, 2023. https://www.wtoc.com/story/37989246/family-remembers-savannah-attorney-killed-in-1989-bombing/ Judge Vance Murder. FBI.gov. Accessed February 1, 2023. https://www.fbi.gov/history/famous-cases/judge-vance-murder Alabama Executes Man for 1989 Mail-Bomb Murder of U.S. Appeals Court Judge Robert S. Vance. Justice.gov. Accessed February 1, 2023. https://www.justice.gov/usao-ndal/pr/alabama-executes-man-1989-mail-bomb-murder-us-appeals-court-judge-robert-s-vance-0 United States of America, Plaintiff-appellee, v. Walter Leroy Moody, Jr. Justia US Law. Accessed February 2, 2023. https://law.justia.com/cases/federal/appellate-courts/F2/977/1425/305286/ 'Why my dad?' Judge recalls father's legacy as bomber's execution nears. AL.com. Accessed February 3, 2023. https://www.al.com/news/birmingham/2018/04/circuit_judge_bob_vance_talks.html Alabama Executes Mail Bomber, 83, the Oldest Inmate Put to Death in Modern Era. The New York Times. Accessed February 3, 2023. https://www.nytimes.com/2018/04/19/us/alabama-execution-walter-leroy-moody.html Forensic Files - Season 3, Episode 5 - Deadly Delivery. Accessed February 3, 2023. https://youtu.be/Ru8PHBVPgLc Episode Music Last Frontier and Falling Rain by Kevin MacLeod. Licensed under Creative Commons; Theme Song “Dark & Troubled” by Pantherburn. Special thanks to Phillip St Ours for permission for use

In this first ever CE episode, we discuss the A-Zs of continuous glucose monitors (CGMs). In specific, our learning objective for the CE are: Describe commonly available types of continuous glucose monitors (CGMs) in the US market and the features and capabilities of these devices. Summarize the evidence and guideline recommendations for use of CGMs in the management of diabetes. Identify the role of the pharmacist in the selection of CGMs and provision of education to patients and providers. Interpret the ambulatory glucose profile (CGM data output) and recommend changes in antihyperglycemic regimen for a patient. ACPE-Accredited Pharmacist CE (1.0 hrs) To obtain CE credit for a $5 fee, visit the following link: https://rfums.wufoo.com/forms/z1qzh5vf0ggr832/. Once payment is successful, you will be redirected to our CE partner (CE Impact) to complete an evaluation and to earn 1.0 hour of CE credit. CE is available for 12 months after episode publication. Key Concepts There are two main types of stand-alone personal CGMs available in the US market – real-time (rtCGM) and intermittently scanning (isCGM). [1] These CGMs vary in their features such as sensor wear time, sensor warm up time, sensor application site, reader availability, approved age for use, fingerstick calibration, non-adjunctive FDA labeling, interconnectability with other technology such as insulin pumps, and drug interactions – these variabilities can be used in decision-making when selecting an appropriate CGM for a patient. [2-7] Based on the evidence for use, both types of CGMs (real-time and intermittently scanning) are recommended in patients with Type 1 and Type 2 diabetes who are on multiple-daily insulin or continuous insulin infusion (pump), patients with Type 2 diabetes on basal insulin therapy, and as adjunct use in patients with diabetes who are pregnant. The strength of recommendations in general is stronger for real-time CGMs than for intermittently scanning CGMs. [1,11] These recommendations are supported by the evidence that CGMs can help improve glucose control, reduce risk of hypoglycemia, diabetes-related hospitalizations, and patient/caregiver satisfaction. Pharmacists play an integral role in education, on-going support, data interpretation, and resulting disease management in patients who qualify for CGM use and providers who care for patients with diabetes. [14] The ambulatory glucose profile is a standardized data output that informs understanding of glucose trends. [15] The recommended goal for most patients is to maintain a glucose range between 70-180 mg/dL with at least 70% of time spent in this range with variability coefficient of no more than 36%. [1,11,15] Supplemental Content Comparison of rtCGM and isCGM devices "Mary's" Example AGP Report (adapted from Battelino et al.) References ElSayed NA, Aleppo G, Aroda VR, et al. American Diabetes Association. Chapter 7. Diabetes technology: Standards of medical care in diabetes - 2023. Diabetes Care. 2023;46(suppl 1):S111-S127. Dexcom G6 User Guide. Dexcom, Inc. 2020. Accessed February 20, 2023. https://s3-us-west-2.amazonaws.com/dexcompdf/G6-CGM-Users-Guide.pdf. Dexcom G7 User Guide. Dexcom, Inc. 2022. Accessed February 20, 2023. https://dexcompdf.s3.us-west-2.amazonaws.com/en-us/G7-CGM-Users-Guide.pdf#page=12 Guardian Connect System User Guide. Medtronic MiniMed. 2020. Accessed February 20, 2023. https://www.medtronicdiabetes.com/sites/default/files/library/download-library/user-guides/Guardian-Connect-System-User-Guide.pdf. Eversense E3 User Guide. Sensionics, Inc. 2022. Accessed February 20, 2023. https://www.eversensediabetes.com/wp-content/uploads/LBL-4002-01-001-Rev-F_Eversense-E3-User-Guide_mgdL_R1_web.pdf FreeStyle Libre 3 User's Manual. Abbott Diabetes Care Inc. 2022. Accessed February 20, 2023. https://freestyleserver.com/Payloads/IFU/2022/q2/ART44140-002_rev-A.pdf FreeStyle Libre 2 User's Manual. Abbott Diabetes Care Inc. 2020. Accessed February 20, 2023. https://freestyleserver.com/Payloads/IFU/2020/q2/ART40703-001_rev-D-Web.pdf. Products. American Diabetes Association. Accessed February 20, 2023. https://consumerguide.diabetes.org/ Wood A, O'Neal D, Furler J, Ekinci EI. Continuous glucose monitoring: a review of the evidence, opportunities for future use and ongoing challenges. Intern Med J. 2018 May;48(5):499-508. Edelman SV, Argento NB, Petty SJ, Hirsch IB. Clinical implications of real-time and intermittently scanned continuous glucose monitoring. Diabetes Care. 2018;41:2265-2274. Fonseca VA, Grunberger G, Anhalt H, et al. Continuous glucose monitoring: A consensus conference of the American Association of Clinical Endocrinologists and American College of Endocrinology. Endocr Pract. 2016;22(8):1008-21. Reiterer F, Polterauer P, Schoemaker M, Schmelzeisen-Redecker G, Freckmann G, Heinemann L, Del Re L. Significance and Reliability of MARD for the Accuracy of CGM Systems. J Diabetes Sci Technol. 2017 Jan;11(1):59-67. doi: 10.1177/1932296816662047. Epub 2016 Sep 25. PMID: 27566735; PMCID: PMC5375072. Food and Drug Administration. Premarket Notification 510(k). 2022. Accessed February 25, 2023. https://www.fda.gov/medical-devices/premarket-submissions-selecting-and-preparing-correct-submission/premarket-notification-510k. Isaacs, Diana. The pharmacist's role in continuous glucose monitoring. Pharmacy Today. 2020;26:37-54. Battelino T, Danne T, Bergenstal RM, et al. Clinical Targets for Continuous Glucose Monitoring Data Interpretation: Recommendations from the International Consensus on Time in Range. Diabetes Care. 2019;42(8):1593-1603.

In 1920 Lena Clarke made history when she became the first woman to be named postmaster of West Palm Beach, Florida. Within a year, she gained notoriety as “the murdering postmistress when she stood trial for killing her lover to cover up an embezzlement scheme.   Want more Southern Mysteries?  Hear the Southern Mysteries show archive of 60+ episodes along with Patron exclusive podcast, Audacious: Tales of American Crime and more when you become a patron of the show. You can immediately access exclusive content now at patreon.com/southernmysteries   Connect   Website: southernmysteries.com Facebook: Southern Mysteries Podcast Twitter: @southernpod_ Instagram: @shannonballard_ Email: southernmysteriespodcast@gmail.com    Episode Sources   Florida history: The story of West Palm Beach's murderous postmistress. The Palm Beach Post. Accessed January 30, 2023. https://www.palmbeachpost.com/story/news/2022/01/09/lena-clarke-mysterious-murderous-postmistress-west-palm-beach/9084494002/   Going Postal, 1920s Style – The Strange Case of Lena Clarke. Palm Beach Past. Accessed January 29, 2023. https://palmbeachpast.org/2021/07/going-postal-1920s-style-the-strange-case-of-lena-clarke/   The Murdering Postal Woman, Lena Clarke, 1921. Historical Crime Detective. Accessed February 2, 2023. https://www.historicalcrimedetective.com/the-murdering-postal-woman-lena-clarke-1921/   Lena Marietta Thankful Clarke. Find A Grave. Accessed February 3, 2023. https://www.findagrave.com/memorial/23950611/lena-marietta_thankful-clarke   Theft of $32,000 Solved by Lena Clarke but Murder of Miltimore is still a mystery. The Orlando Sentinel. Accessed February 3, 2023. https://www.newspapers.com/image/313585521/?terms=lena%20clarke&match=1   The Life of Lena Clarke In Her Own Pen. The Miami Herald. Accessed February 3, 2023. https://www.newspapers.com/image/616088404/?terms=lena%20clarke&match=1   Lena Clarke Murder Trial. The MIami Herald. Accessed February 3, 2023. https://www.newspapers.com/image/616088368/?terms=lena%20clarke&match=1   Postmistress Called Insane Freed of Murder. The New York Daily News. Accessed February 3, 2023. https://www.newspapers.com/image/410910479/?terms=lena%20clarke&match=1   Episode Music St. Francis by by Josh Lippi & The Overtimers. Licensed under Creative Commons; Theme Song “Dark & Troubled” by Pantherburn. Special thanks to Phillip St Ours for permission for use

This week on Pharm5: Voluntary eyedrop recalls Bempedoic acid lowers MACE risk LDL

Episode 131: Breastfeeding Part 2Lia and Aruna explain some updates given by the American Academy of Pediatrics regarding breastfeeding. Dr. Arreaza adds some comments about breastfeeding. Written by Aruna Sridharan, MS4, and Lia Khachikyan, MS4, Ross University School of Medicine. Comments by Hector Arreaza, MD.You are listening to Rio Bravo qWeek Podcast, your weekly dose of knowledge brought to you by the Rio Bravo Family Medicine Residency Program from Bakersfield, California, a UCLA-affiliated program sponsored by Clinica Sierra Vista, Let Us Be Your Healthcare Home. This podcast was created for educational purposes only. Visit your primary care provider for additional medical advice.The motivation for this episode was a recent publication by the American Academy of Pediatrics, on June 27, 2022, titled Policy Statement: Breastfeeding and the Use of Human Milk. During this episode, we included updated information along with other useful material.Duration of breastfeeding:The American Academy of Pediatrics (AAP), World Health Organization (WHO), and Center of Disease Control (CDC) recommend exclusive breastfeeding at least for the first 6 months, after which one can start to introduce complementary pureed foods. The US Department of Agriculture states that initiating complementary foods earlier than 6 months offers no benefit to the baby and can even be associated with a higher risk of overweight or obesity, especially if introduced before 4 months. Mothers are then encouraged to continue breastfeeding for at least one year and can further continue up to 2 years of age or longer - as long as mutually desired by mother and child. This is an update from previous recommendations regarding the duration of breastfeeding until 1 year of age.Composition of human breastmilk:As the sole source of nutrition for infants in the first 6 months of life, breast milk plays a critical role in development. Human milk has a unique composition of proteins, fats, and lactose, as well as vitamins, electrolytes, antimicrobial, anti-inflammatory immunoregulatory agents, and living leukocytes, all of which contribute to the developing immune system of the child. Breast milk is rich in Vitamins B1, B2, and B6, Vitamins C, A, E, Ca, Mg, phosphate, and folate. However, it is low in Vitamins K, D, B12, and iron, therefore supplementation of these nutrients is required. It is important for mothers to consume an adequate and healthy diet for their breastmilk to contain appropriate levels of these nutrients. Water-soluble and Fat-soluble vitamins can be low in breast milk if the mother has a deficiency. Selenium can be low if maternal serum levels are low. Dietary iodine deficiency may also be exacerbated by smoking; iron deficiency; and consumption of large amounts of foods that interfere with the production of thyroid hormones, known as goitrogens, including Brussels sprouts, kale, cabbage, cauliflower, and broccoli. Maternal diet:Mothers should consume iodine-rich foods, such as lean meat, eggs, dairy, beans, and lentils. It is important to choose a variety of whole grains, as well as fruits and vegetables, and continue taking multivitamins. Fun fact: Different foods will change the flavor of your breast milk. This will expose your baby to different tastes, which might help him or her more easily accept solid foods down the road! It is recommended that mothers consume 290 mcg of iodine and 550mg of choline a day. Is there anything that mothers should avoid in their diet?-Limit seafood: Although fish is a good source of protein and lean meat, it contains some mercury, which can be transferred to the baby's diet. High amounts of mercury can have an adverse effect on the baby's brain and nervous system.-Limit caffeine: Also, we know a lot of people love their morning dose of espresso! Low to moderate amounts, equivalent to 2-3 cups of coffee per day, do not adversely affect the infant. However, anything more than around 300 mg of caffeine can cause irritability, poor sleeping patterns, fussiness, and jitteriness. Remember! This also includes sodas, energy drinks, tea, and even chocolate! As a reminder, one cup of coffee can have 95mg of caffeine.Vegan mothers: Vegetarian/vegan mothers may have very limited amounts of vitamin B12 in their bodies, which can result in neurological damage to the baby. Iron levels may also be sparse since plant-based foods only contain non-heme iron, which is less absorbable than heme iron. The American Dietetic Association recommends supplementation of vitamin B12, iron, and other nutrients such as choline, zinc, iodine, or omega-3 fats. Benefits:For the baby: Studies show that exclusively breastfeeding for 6 months decreased rates of neonatal and infant mortality as well as pediatric disorders such as otitis media, diabetes mellitus, obesity, lower respiratory tract disorders, asthma, atopic dermatitis, sudden infant death syndrome (SIDS), severe diarrhea, and inflammatory bowel disease. The longer an infant is breastfed, the greater the protection from certain illnesses and long-term diseases. For the mother: The longer a mother breastfeeds, the greater the benefits to her health as well. Mothers who breastfeed experience a lower risk of hypertension, type 2 diabetes, and breast, ovarian, and endometrial cancers. Contraindications:-Alcohol: Having up to 1 drink per day is not harmful to the baby, especially if the mother waits at least 2 hours before feeding the infant. This allows time for the blood alcohol concentration in the breastmilk to decrease. Consuming more than 2 standard alcoholic drinks daily is highly discouraged.-Tobacco: Cigarette smoking, or the use of nicotine products, is associated with decreased production of milk, shorter lactation time, and an increased risk of SIDS, asthma, and other respiratory illnesses in infants. Therefore, mothers should be strongly encouraged to stop smoking and minimize secondhand exposure. We know it is very difficult for people to quit abruptly. While transitioning to cessation, mothers should be counseled to smoke right after breastfeeding to allow the greatest amount of time for nicotine to exit the body until the next feed. Other cessation alternatives such as the patch or gum can also be used during breastfeeding.Varenicline: No human data is available to assess the risk of infant harm, but it is likely excreted in the milk, no data on the assessment of milk production.-Other substances: Marijuana, opioids, amphetamine, cocaine, and other illicit drugs are contraindicated due to their effects on neurodevelopmental behaviors. If these substances have been used intrapartum or during breastfeeding, it is important to monitor the baby for Neonatal Abstinence Syndrome. Some symptoms include poor weight gain, tremors, high-pitched crying, stuffy nose, poor feeding/sucking, seizures, irritability, poor sleep, vomiting, and diarrhea.-Maternal infections: Breastfeeding is not contraindicated during most maternal infections. Some exceptions include HIV, Human T-cell lymphotropic virus type I or II, untreated brucellosis, Ebola virus, or active Herpetic lesions on the breast. Women with herpetic lesions may breastfeed from the unaffected breast. -Maternal medications: Medications are relatively safe for breastfed babies, but some contraindications include anticancer drugs, oral retinoids, lithium, iodine, and amiodarone. Mothers should go over their medication list with their primary physician.Pregnancy and Lactation Labeling Final Rule (PLLR): Classification of drugs according to their impact on pregnancy and breastfeeding (categories A, B, C, D, X) was started in 1979, but it was stopped in 2015 and replaced by the Pregnancy and Lactation Labeling Final Rule (PLLR). The former categories were replaced with narrative sections and subsections to include: Pregnancy (including labor and delivery), Lactation, and information for Females and Males of Reproductive Potential (pregnancy testing, contraception, infertility).Role of the physician and stigmas:It is well known that breastfeeding can strengthen the bond between the mother and her child. Therefore, when latching becomes a problem, mothers are quick to become discouraged. If this happens, pediatricians should educate the parents that many breastfeeding problems commonly arise between 4-7 days after birth. Sometimes, exclusive or any amount of breastfeeding is not always possible, despite the mother's best intentions. This can understandably cause them to feel a lot of guilt and disappointment as a new mother. Physicians should provide a safe, non-judgmental environment for the parents to openly discuss their difficulties while educating them on proper latching techniques and other alternatives for breastfeeding.Conclusion: Now we conclude our episode number 131 “Breastfeeding Part 2.” Aruna and Lia explained that the American Academy of Pediatrics now recommends continued breastfeeding until 2 years or as long as the mother and the baby desire it. It is important to remember some contraindications such as babies with galactosemia, mothers who are using illicit drugs, and some maternal infections such as HIV, untreated brucellosis, and Ebola virus. This week we thank Hector Arreaza, Aruna Sridharan, and Lia Khachikyan. Audio editing by Adrianne Silva.Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week! _____________________Dror, D. K., & Allen, L. H. (2018, May 29). Overview of Nutrients in Human Milk. PubMed Central (PMC). https://doi.org/10.1093/advances/nmy022.Meek, J. Y., Noble, L., & Breastfeeding, S. O. (2022, July 1). Policy Statement: Breastfeeding and the Use of Human Milk. American Academy of Pediatrics. https://doi.org/10.1542/peds.2022-057988.“Maternal Diet.” Centers for Disease Control and Prevention, Centers for Disease Control and Prevention, 17 May 2022, https://www.cdc.gov/breastfeeding/breastfeeding-special-circumstances/diet-and-micronutrients/maternal-diet.html.Breastfeeding FAQs. Centers for Disease Control and Prevention. https://www.cdc.gov/breastfeeding/faq/index.htm. Accessed February 21, 2023. Butte, Nancy F., and Alison Stuebe. Maternal nutrition during lactation. UpToDate, July 13, 2022. https://www.uptodate.com/contents/maternal-nutrition-during-lactation. Accessed March 6, 2023. Royalty-free music used for this episode: “Gushito - Burn Flow." Downloaded on October 13, 2022, from https://www.videvo.net/

Roseann Quinn was a young, single school teacher working at St. Joseph's School for the Deaf and pursuing a graduate degree that would help her advance her career. She was independent and had a bright future. Then on January 2, 1973, she was brutally murdered in her New York apartment by a man she met at a neighborhood bar. Her death would become a talking point for those against the Woman's Liberation Movement—citing her "high risk" lifestyle as the catalyst for her own demise. Of course we know that the only one to blame here is the vicious killer himself, and Roseann Quinn was merely a symbol for his rage.Associated Press. 1973. "Murdered teacher was dedicated to her work with deaf children." Reporter Dispatch, January 5: 2.Churcher, Sharon. 1999. "Could Sex and the City lead to murder?" Mail on Sunday, February 14.Ebert, Roger. 1977. Looking for Mr. Goodbar. January 1. Accessed February 8, 2023. https://www.rogerebert.com/reviews/looking-for-mr-goodbar-1977.Fosburgh, Lacey. 1977. Closing Time: The True Story of the "Looking for Mr. Goodbar" Murder. New York, NY: Dellacorte Press.—. 1973. "A man seen with teacher on slaying night is sought." New York Times, January 6: 16.—. 1973. "Suspect seized in Indiana in teacher's slaying here." New York Times, January 10: 1.Gelb, Arthur. 2003. City Room. New York, NY: Putnam.Kaufman, Michael. 1973. "Teacher, 28, slain in her apartment on West 72d Street." New York Times, January 5: 1.Knight, Michael. 1973. "Suspect in killing of a teacher on West Side hangs himself." New York Times, May 6.McFadden, Robert. 1973. "Police issue a sketch of witness they hope will identify killer of teacher." New York Times, January 7: 39.New York Times. 1973. "Insanity defense planned in killing of teacher here." New York Times, February 2: 14.Weisman, Steven R. 1973. "Corrections board assails city aides on Tombs suicide." New York Times, July 22: 33.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Historian Richard A. Gabriel neatly summarized Philip II's legacy, “Had there been no Philip to bring the Macedonian national state into existence, to assemble the economic and military resources to unite Greece, to create the bold strategic vision of conquering Persia, and to invent the first modern, tactically sophisticated and strategically capable military force in Western military history as the instrument for accomplishing that vision, the exploits of Philip's son Alexander is Asia would not have been possible.” Give this episode a listen and learn more about the charismatic and amazing life of Philip II of Macedonia You can find the Hardtack socials via linktree. If you have any feedback on Hardtack episodes or suggestions for future episodes, please send an email to hardtackpod@gmail.com Don't forget to rate and subscribe! Make your Own Hardtack! Hardtack Recipe (Survival Bread) - Bread Dad Sources: Philip II of Macedon: Great than Alexander by Richard A. Gabriel The Anabasis of Alexander by Arrian Tucker, Spencer C., and Lee L. Brice. "Philip II of Macedon." In World at War: Understanding Conflict and Society, ABC-CLIO, 2023. Accessed February 13, 2023. https://worldatwar2-abc-clio-com.ezproxy2.apus.edu/Search/Display/1722643. Diodorus on the death of Philip - Livius Herodotus on the Macedonian royal House - Livius --- Send in a voice message: https://anchor.fm/hardtackpod/message Support this podcast: https://anchor.fm/hardtackpod/support

Chelsea and I continue our series about the Christian revivals in American history.Solomon Stoddard, a fiery preacher saw several revivals in his 60 years pastoring the church at Northampton, Massachusetts, but he embraced and expanded the Half-Way Covenant. Stoddard allowed open membership and open communion. The Northampton church grew to over 600 members, but over time the majority were likely unbelievers.Stoddard's grandson Jonathan Edwards would become the new pastor of the church. He would follow in the footsteps of revivalist preaching, with his famous sermon "Sinners in the Hands of an Angry God." Edwards would also see that the Half-Way Covenant and Stoddard's church polity was enshrining the "dead religion" they were intended to solve.Scriptures Referenced:Revelation 3:161 Corinthians 11:30Sources Consulted:"Spiritual Awakenings in North America: Christian History Timeline," Christianity Today, Accessed February 26, 2023.Schafer, T. A.. "Jonathan Edwards." Encyclopedia Britannica, February 18, 2023.Jack Zavada, "Jonathan Edwards, Reformed Church Pioneer: Famous Revivalist Preacher of the Great Awakening," Learn Religions, August 9, 2019.Martin Kelly, "Jonathan Edwards: Colonial Clergyman of the Great Awakening," ThoughtCo, July 3, 2019.Jonathan Edwards, "Sinners in the Hands of an Angry God."*** Castle Rock Women's Health is a pro-life and pro-women health care ministry. They need your help to move into a new office to serve the community better. Please consider a monthly or one-time donation. ***We value your feedback!Have questions for Truthspresso? Contact us!

In this episode of the Tech Policy Leaders podcast, Meredith Broussard discusses her new book ‘More Than a Glitch,' which takes a critical look at algorithms and the people who create them.   Bio Website LinkedIn @MerBroussard   Data journalist Meredith Broussard is an associate professor at the Arthur L. Carter Journalism Institute of New York University, research director at the NYU Alliance for Public Interest Technology, and the author of several books, including “Artificial Unintelligence: How Computers Misunderstand the World” and “More Than a Glitch: Confronting Race, Gender, and Ability Bias in Tech.” Her academic research focuses on artificial intelligence in investigative reporting and ethical AI, with a particular interest in using data analysis for social good. She appeared in the 2020 documentary Coded Bias, an official selection of the Sundance Film Festival that was nominated for an Emmy Award and an NAACP Image Award. Resources (2022) More Than a Glitch: Confronting Race, Gender, and Ability Bias in Tech. Available at: https://bookshop.org/p/books/more-than-a-glitch-confronting-race-gender-and-ability-bias-in-tech-meredith-broussard/18634652?ean=9780262047654 (Accessed: February 27, 2023).      

Ellen Swallow Richards was a big part of the establishment of home economics as a field.  But well before that, she broke a lot of ground and was often way ahead of her time. Research: Bettex, Morgan. “A life filled with firsts.” MIT News. 1/26/2011. https://news.mit.edu/2011/timeline-richards-0126 Britannica, The Editors of Encyclopaedia. "Ellen Swallow Richards". Encyclopedia Britannica, 29 Nov. 2022, https://www.britannica.com/biography/Ellen-Swallow-Richards. Accessed 8 February 2023. Chapman, Sasha. “The Woman Who Gave Us the Science of Normal Life.” Nautilus. 3/28/2017. https://nautil.us/the-woman-who-gave-us-the-science-of-normal-life-236534/ Daniels, Elizabeth A. “The Disappointing First Thrust of Euthenics.” Vassar Encyclopedia. https://vcencyclopedia.vassar.edu/interviews-and-reflections/the-disappointing-first-thrust-of-euthenics/ Durant, Elizabeth. “Ellencyclopedia.” MIT Technology Review. 8/15/2007. https://www.technologyreview.com/2007/08/15/36578/ellencyclopedia/ Dyball, Robert and Liesel Carlsson. Human Ecology Review, Vol. 23, No. 2, Special Issue: Human Ecology—A Gathering of Perspectives: Portraits from the Past—Prospects for the Future (2017). Via JSTOR. https://www.jstor.org/stable/26367977 Egan, Kristen R. “Conservation and Cleanliness: Racial and Environmental Purity in Ellen Richards and Charlotte Perkins Gilman.” Women's Studies Quarterly , FALL/WINTER 2011, Vol. 39, No. 3/4. Via JSTOR. https://www.jstor.org/stable/41308345 Hunt, Caroline Lousia. “The life of Ellen H. Richards, 1842-1911.” Boston: Whitcomb & Barrows. 1918. https://archive.org/details/lifeofellenhrich1918hunt Kwallek, Nancy. "Ellen Swallow Richards: visionary on home and sustainability." Phi Kappa Phi Forum, vol. 92, no. 2, summer 2012, pp. 8+. Gale General OneFile, link.gale.com/apps/doc/A291498991/GPS?u=mlin_n_melpub&sid=bookmark-GPS&xid=7050163b. Accessed 6 Feb. 2023. McNeill, Leila. “The First Female Student at MIT Started an All-Women Chemistry Lab and Fought for Food Safety.” Smithsonian. 12/18/2018. https://www.smithsonianmag.com/science-nature/first-female-student-mit-started-women-chemistry-lab-food-safety-180971056/ Richardson, Barbara. “Ellen Swallow Richards: Advocate for ‘Oecology,' Euthenics and Women's Leadership in Using Science to Control the Environment.” Michigan Sociological Review , Fall 2000, Vol. 14 (Fall 2000). Via JSTOR. https://www.jstor.org/stable/40969050 Smith, Coleen. "The William Barton Rogers Building - The Door Opens." Clio: Your Guide to History. October 24, 2022. Accessed February 8, 2023. https://theclio.com/entry/147331 Smith, Nancy DuVergne. “Scene at MIT: Ellen Swallow Richards leads the Women's Laboratory.” MIT News. 3/21/2017. https://news.mit.edu/2017/scene-at-mit-ellen-swallow-richards-womens-laboratory-0321 Talbot, H.P. “Ellen Swallow Richards.” Technology Review, volume 13, pp. 365-373. https://wayback.archive-it.org/7963/20190702115713/https://libraries.mit.edu/archives/exhibits/esr/esr-biography.html Vassar Encyclopedia. “Ellen Swallow Richards '1870.” https://vcencyclopedia.vassar.edu/distinguished-alumni/ellen-swallow-richards/ See omnystudio.com/listener for privacy information.

Chelsea and I continue our series about the Christian revivals in American history. Solomon Stoddard, a fiery preacher saw several revivals in his 60 years pastoring the church at Northampton, Massachusetts, but he embraced and expanded the Half-Way Covenant. Stoddard allowed open membership and open communion. The Northampton church grew to over 600 members, but over time the majority were likely unbelievers. Stoddard's grandson Jonathan Edwards would become the new pastor of the church. He would follow in the footsteps of revivalist preaching, with his famous sermon "Sinners in the Hands of an Angry God." Edwards would also see that the Half-Way Covenant and Stoddard's church polity was enshrining the "dead religion" they were intended to solve. Scriptures Referenced: Revelation 3:16 1 Corinthians 11:30 Sources Consulted: "Spiritual Awakenings in North America: Christian History Timeline," Christianity Today, Accessed February 26, 2023. Schafer, T. A.. "Jonathan Edwards." Encyclopedia Britannica, February 18, 2023. Jack Zavada, "Jonathan Edwards, Reformed Church Pioneer: Famous Revivalist Preacher of the Great Awakening," Learn Religions, August 9, 2019. Martin Kelly, "Jonathan Edwards: Colonial Clergyman of the Great Awakening," ThoughtCo, July 3, 2019. Jonathan Edwards, "Sinners in the Hands of an Angry God." *** Castle Rock Women's Health is a pro-life and pro-women health care ministry. They need your help to move into a new office to serve the community better. Please consider a monthly or one-time donation. *** We value your feedback! Have questions for Truthspresso? Contact us!

There are lesser known stories of enslaved men and women who fought for their freedom in court. Elizabeth Key was at the center of one of the most important colonial court cases involving slavery. Henrietta Wood made history when she sued the man who kidnapped and enslaved her. Want more Southern Mysteries?  Hear the Southern Mysteries show archive of 60+ episodes along with Patron exclusive podcast, Audacious: Tales of American Crime and more when you become a patron of the show. You can immediately access exclusive content now at patreon.com/southernmysteries Connect Website: southernmysteries.com Facebook: Southern Mysteries Podcast Twitter: @southernpod_ Instagram: @shannonballard_ Email: southernmysteriespodcast@gmail.com    Episode Sources Elizabeth Key. Women in History. Accessed January 10,2023 Elizabeth Key. Library of Virginia. Accessed January 13, 2023 Elizabeth Key and Her History-Changing Lawsuit. ThoughtCo. Accessed January 14, 2023 The Case of Elizabeth Key, 1655/1656 Northumberland County Record Books, 1652-1658, fols. 66-67, 85; 1658-1660, fol. 28; Northumberland County Order Book, 1652-1665, fols. 40, 46, 49. University of Chicago Taunya Lovell Banks, "Dangerous Woman: Elizabeth Key's Freedom Suit - Subjecthood and Racialized Identity in Seventeenth Century Colonial Virginia", 41 Akron Law Review 799 (2008), Digital Commons Law, University of Maryland.  Sweet Taste of Liberty Open Source Notebook. Caleb McDaniel. Accessed January 14, 2023 In 1870, Henrietta Wood Sued for Reparations—and Won. Smithsonian Magazine. Accessed February 1, 2023   Episode Music Magic Forest by Sir Cubworth Licensed under a Creative Commons; Theme Song “Dark & Troubled” by Pantherburn. Special thanks to Phillip St Ours for permission for use

Chelsea and I continue our series about the Christian revivals in American history.Solomon Stoddard, a fiery preacher saw several revivals in his 60 years pastoring the church at Northampton, Massachusetts, but he embraced and expanded the Half-Way Covenant. Stoddard allowed open membership and open communion. The Northampton church grew to over 600 members, but over time the majority were likely unbelievers.Stoddard's grandson Jonathan Edwards would become the new pastor of the church. He would follow in the footsteps of revivalist preaching, with his famous sermon "Sinners in the Hands of an Angry God." Edwards would also see that the Half-Way Covenant and Stoddard's church polity was enshrining the "dead religion" they were intended to solve.Scriptures Referenced:Revelation 3:161 Corinthians 11:30Sources Consulted:"Spiritual Awakenings in North America: Christian History Timeline," Christianity Today, Accessed February 26, 2023.Schafer, T. A.. "Jonathan Edwards." Encyclopedia Britannica, February 18, 2023.Jack Zavada, "Jonathan Edwards, Reformed Church Pioneer: Famous Revivalist Preacher of the Great Awakening," Learn Religions, August 9, 2019.Martin Kelly, "Jonathan Edwards: Colonial Clergyman of the Great Awakening," ThoughtCo, July 3, 2019.Jonathan Edwards, "Sinners in the Hands of an Angry God."*** Castle Rock Women's Health is a pro-life and pro-women health care ministry. They need your help to move into a new office to serve the community better. Please consider a monthly or one-time donation. ***We value your feedback!Have questions for Truthspresso? Contact us!

This week on Pharm5: Ivermectin fails against COVID-19 Cabenuva noninferior to Biktarvy Syfovre for geographic atrophy Aspirin for pre-eclampsia prevention TRUNCATE-TB results could shorten TB treatment Connect with us! Listen to our podcast: Pharm5 Follow us on Twitter: @LizHearnPharmD References: Naggie S, Boulware DR, Lindsell CJ, et al. Effect of higher-dose ivermectin for 6 days vs placebo on time to sustained recovery in outpatients with covid-19. JAMA. February 2023. doi:10.1001/jama.2023.1650. Efficacy: Cabenuva (cabotegravir; Rilpivirine). Efficacy: Every 2 Month | CABENUVA Official HCP Website. http://bit.ly/3kpnkdU. Accessed February 23, 2023. VIIV healthcare announces positive data demonstrating long-acting injectable Cabenuva (cabotegravir, Rilpivirine) is as effective as daily oral biktarvy (BIC/FTC/TAF) for the treatment of HIV-1. ViiV Healthcare. http://bit.ly/3m14uKy. Accessed February 23, 2023. Low-dose aspirin use for the prevention of preeclampsia and related morbidity and mortality. ACOG. http://bit.ly/3kuekE7. Accessed February 23, 2023. Mendoza M, Bonacina E, Garcia-Manau P. Aspirin discontinuation at 24 to 28 weeks' gestation in pregnancies a high risk of preterm preeclampsia: a randomized clinical trial. JAMA. February 2023. doi: 10.1001/jama.2023.0691. FDA Oks first drug for geographic atrophy, a major cause of adult blindness. FDA OKs First Drug for Geographic Atrophy, a Major Cause of Adult Blindness. http://bit.ly/3ZgFwoE. Published February 17, 2023. Accessed February 22, 2023. Paton NI, Cousins C, Suresh C, et al. Treatment strategy for rifampin-susceptible tuberculosis. New England Journal of Medicine. 2023. doi:10.1056/nejmoa2212537 Treatment for TB disease. Centers for Disease Control and Prevention. http://bit.ly/3Y5HxTW. Published March 7, 2022. Accessed February 23, 2023.

Welcome to the 2 View - Episode 24 Welcome to Episode 24 of “The 2 View,” the podcast for EM and urgent care nurse practitioners and physician assistants! Show Notes for Episode 24 of “The 2 View” – New street drug xylazine/"tranq," app for EM coding changes, FPL injuries, hemorrhoids. Molnupiravir Butler CC, Hobbs FDR, Gbinigie OA, et al. Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial. Lancet. PubMed. NIH: National Library of Medicine, National Center for Biotechnology Information. Published January 28, 2023. Accessed February 21, 2023. https://pubmed.ncbi.nlm.nih.gov/36566761/ Molnupiravir. COVID-19 Treatment Guidelines. NIH. Last Updated: September 26, 2022. Accessed February 21, 2023. https://www.covid19treatmentguidelines.nih.gov/therapies/antivirals-including-antibody-products/molnupiravir/ Easy Emergency Medicine Coding Calculator American Medical Association. 2023 Emergency Medicine Coding Guide. MDCalc. Accessed February 21, 2023. https://www.mdcalc.com/calc/10454/2023-emergency-medicine-coding-guide CPT Evaluation and Management (E/M) Code and Guideline Changes. Ama-assn.org. AMA: American Medical Association. Accessed February 21, 2023. https://www.ama-assn.org/system/files/2023-e-m-descriptors-guidelines.pdf Graham. 2023 Emergency Medicine Level of Service/Billing Guidelines Overview. Published December 31, 2022. Accessed February 21, 2023. https://www.youtube.com/watch?v=WuV8O3SuXJI The Center for Medical Education. Documentation Changes that Can Help Your Practice. Published August 16, 2022. Accessed February 21, 2023. https://www.youtube.com/watch?v=gHLBjzQt4vo Xylazine DEA Joint Intelligence Report. The Growing Threat of Xylazine and its Mixture with Illicit Drugs. U.S. Department of Justice Drug Enforcement Administration. Dea.gov. Published October 2022. Accessed February 21, 2023. https://www.dea.gov/sites/default/files/2022-12/The%20Growing%20Threat%20of%20Xylazine%20and%20its%20Mixture%20with%20Illic it%20Drugs.pdf FDA warns about the risk of xylazine exposure in humans. Fda.gov. FDA. Published November 8, 2022. Accessed February 21, 2023. https://www.fda.gov/media/162981/download Hoffman J. Tranq dope: Animal Sedative Mixed with Fentanyl Brings Fresh Horror to U.S. Drug Zones. The New York Times. Published January 7, 2023. Accessed February 21, 2023. https://www.nytimes.com/2023/01/07/health/fentanyl-xylazine-drug.html. National Institute on Drug Abuse. Xylazine. National Institute on Drug Abuse: Advancing Addiction Science. Published April 21, 2022. Accessed February 21, 2023. https://nida.nih.gov/research-topics/xylazine Overdose C on O. Toxicity of Xylazine and How It Impacts People Who Use Drugs by Dr. Joseph D'Orazio. Published June 15, 2022. Accessed February 21, 2023. https://www.youtube.com/watch?v=Rqpf0jIuyCo Flexor Pollicis Longus and Other Thumb Injuries Gault D. A review of repaired flexor tendons. J Hand Surg Br. ScienceDirect. Published October 1987. Accessed February 21, 2023. https://www.sciencedirect.com/science/article/abs/pii/0266768187901811 Urbaniak JR. Repair of the flexor pollicis longus. Hand Clin. Europe PMC. Published February 1, 1985. Accessed February 21, 2023. https://europepmc.org/article/med/3912396 Hemorrhoids Procedure Review: Thrombosed Hemorrhoids. EM:RAP. EM:RAP.ORG. Published April 2018. Accessed February 21, 2023. https://www.emrap.org/episode/emrapliveapril/procedurereview Zuber TJ. Hemorrhoidectomy for Thrombosed External Hemorrhoids. Am Fam Physician. AAFP. Published 2002. Accessed February 21, 2023. https://www.aafp.org/pubs/afp/issues/2002/0415/p1629.html Recurring Sources Center for Medical Education. Ccme.org. http://ccme.org The Proceduralist. Theproceduralist.org. http://www.theproceduralist.org The Procedural Pause. Emergency Medicine News. Lww.com. https://journals.lww.com/em-news/blog/theproceduralpause/pages/default.aspx The Skeptics Guide to Emergency Medicine. Thesgem.com. http://www.thesgem.com Trivia Question: Send answers to 2viewcast@gmail.com Be sure to keep tuning in for more great prizes and fun trivia questions! Once you hear the question, please email us your guesses at 2viewcast@gmail.com and tell us who you want to give a shout-out to. Be sure to listen in and see what we have to share!

Mountain goats spend winter above treeline on windswept ridges, while coastal populations migrate downhill to spend winters in low-elevation forested areas. Cumulative snow depth varies more than recently fallen snow, which could explain the negative effects of cumulative snow depth on movements and winter range size. Reduced movements during snowfalls, possibly related to low visibility, could also explain these results. Mountain goat ranges were smaller in late winter than early winter but increased with day length as winter advanced. This may be because increased day length enables mountain goats to be active for longer periods and thus travel longer distances.     Richard, J.H. et al. (2014) The effect of snow on space use of an alpine ungulate: Recently fallen snow tells more than cumulative snow depth, Canadian Journal of Zoology. Available at: https://cdnsciencepub.com/doi/10.1139/cjz-2014-0118 (Accessed: February 22, 2023).   Music from #Uppbeat (free for Creators!): https://uppbeat.io/t/paul-yudin/your-adrenaline License code: QWS1TG5BYTFK2PCL

Chelsea and I start a new series about the Christian revivals in American history.The controversy over the recent "Asbury revival" drove us to ask the question "What is a revival?"Using a dictionary, Scripture, and a Spurgeon quote, we come up with a working definition of a revival. Then, we dive deep into the setting of the American colonies in the 1600's and early 1700's.As church life was decaying since the first generation of pilgrims covenanted the first Congregational churches in the Massachusetts Bay colony, pastors begin to look for revival.Congregationalist churches practiced infant baptism but only granted church membership to attendees who could evidence regeneration. As the first generation's children became adults but didn't become fully covenanted members, could their children be baptized? Could they partake of the Lord's Supper? Boston pastor Richard Mather argued that the children were proper covenant members in some sense. The question remained whether to baptize children of "unregenerate" members into the third generation.In 1662, Mather collaborated on what became known as the Half-Way Covenant to revive the church with a structural and political solution. Would it work? Scriptures Referenced:Psalm 85:6-8Acts 2:16-18Matthew 7:15-16Titus 3:9,5Sources Consulted:"Revival," Websters Dictionary 1828, Accessed February 19, 2023.C. H. Spurgeon, "What Is a Revival?" Sword and Trowel, December 1866.Britannica, T. Editors of Encyclopaedia. "Richard Mather." Encyclopedia Britannica, January 1, 2023."BIOGRAPHY: RICHARD MATHER (1596-1669)," The Mather Project, Accessed February 19, 2023.Richard Mather, "A DISPUTATION CONCERNING Church-Members AND THEIR CHILDREN IN ANSWER to 21 QUESTIONS," 1657.*** Castle Rock Women's Health is a pro-life and pro-women health care ministry. They need your help to move into a new office to serve the community better. Please consider a monthly or one-time donation. ***We value your feedback!Have questions for Truthspresso? Contact us!

Chelsea and I start a new series about the Christian revivals in American history.The controversy over the recent "Asbury revival" drove us to ask the question "What is a revival?"Using a dictionary, Scripture, and a Spurgeon quote, we come up with a working definition of a revival. Then, we dive deep into the setting of the American colonies in the 1600's and early 1700's.As church life was decaying since the first generation of pilgrims covenanted the first Congregational churches in the Massachusetts Bay colony, pastors begin to look for revival.Congregationalist churches practiced infant baptism but only granted church membership to attendees who could evidence regeneration. As the first generation's children became adults but didn't become fully covenanted members, could their children be baptized? Could they partake of the Lord's Supper? Boston pastor Richard Mather argued that the children were proper covenant members in some sense. The question remained whether to baptize children of "unregenerate" members into the third generation.In 1662, Mather collaborated on what became known as the Half-Way Covenant to revive the church with a structural and political solution. Would it work? Scriptures Referenced:Psalm 85:6-8Acts 2:16-18Matthew 7:15-16Titus 3:9,5Sources Consulted:"Revival," Websters Dictionary 1828, Accessed February 19, 2023.C. H. Spurgeon, "What Is a Revival?" Sword and Trowel, December 1866.Britannica, T. Editors of Encyclopaedia. "Richard Mather." Encyclopedia Britannica, January 1, 2023."BIOGRAPHY: RICHARD MATHER (1596-1669)," The Mather Project, Accessed February 19, 2023.Richard Mather, "A DISPUTATION CONCERNING Church-Members AND THEIR CHILDREN IN ANSWER to 21 QUESTIONS," 1657.*** Castle Rock Women's Health is a pro-life and pro-women health care ministry. They need your help to move into a new office to serve the community better. Please consider a monthly or one-time donation. ***We value your feedback!Have questions for Truthspresso? Contact us!

Chelsea and I start a new series about the Christian revivals in American history. The controversy over the recent "Asbury revival" drove us to ask the question "What is a revival?" Using a dictionary, Scripture, and a Spurgeon quote, we come up with a working definition of a revival. Then, we dive deep into the setting of the American colonies in the 1600's and early 1700's. As church life was decaying since the first generation of pilgrims covenanted the first Congregational churches in the Massachusetts Bay colony, pastors begin to look for revival. Congregationalist churches practiced infant baptism but only granted church membership to attendees who could evidence regeneration. As the first generation's children became adults but didn't become fully covenanted members, could their children be baptized? Could they partake of the Lord's Supper? Boston pastor Richard Mather argued that the children were proper covenant members in some sense. The question remained whether to baptize children of "unregenerate" members into the third generation. In 1662, Mather collaborated on what became known as the Half-Way Covenant to revive the church with a structural and political solution. Would it work? Scriptures Referenced: Psalm 85:6-8 Acts 2:16-18 Matthew 7:15-16 Titus 3:9,5 Sources Consulted: "Revival," Websters Dictionary 1828, Accessed February 19, 2023. C. H. Spurgeon, "What Is a Revival?" Sword and Trowel, December 1866. Britannica, T. Editors of Encyclopaedia. "Richard Mather." Encyclopedia Britannica, January 1, 2023. "BIOGRAPHY: RICHARD MATHER (1596-1669)," The Mather Project, Accessed February 19, 2023. Richard Mather, "A DISPUTATION CONCERNING Church-Members AND THEIR CHILDREN IN ANSWER to 21 QUESTIONS," 1657. *** Castle Rock Women's Health is a pro-life and pro-women health care ministry. They need your help to move into a new office to serve the community better. Please consider a monthly or one-time donation. *** We value your feedback! Have questions for Truthspresso? Contact us!

Most of us have experienced feelings of doubt and unworthiness at some point in our lives. But when our accomplishments are a result of our own knowledge, hard work, and preparation and we still feel inadequate ... we're probably suffering from impostor syndrome. The impostor “syndrome” is a feeling that if we've achieved something it is not because of our competencies, but because of some oversight or stroke of luck. We therefore feel like frauds or “impostors.” and we tend to discount the hard work we have done. Andrew and Louise discuss Imposter Syndrome with Mary Watkins, a local mental health counsellor. They find the whole experience of chatting with Mary so enlightening and by the end of the podcast both Andrew and Louise had a few light bulb moments. 1m: 48s What Is It? 5m :09s What Does It Feel Like? 5m: 55s How Can We Recognise It? 10m: 38s Where Does It All Start? 13m : 06s Who Is More Susceptible? 14m: 02s How Limiting Can It Be? 22m: 09s What Can We Do About It? 23m :48s Going To See A Counsellor 26m: 23s Social Media Pressure 30m: 05s Shiny Object Syndrome 30m: 49s How Do We Know When The Need To Continually Learn Is Problematic? 35m: 27s Supporting And Helping Others Episode notes Clance, P. and Imes, S., 1978. The imposter phenomenon in high achieving women: Dynamics and therapeutic intervention. Psychotherapy: Theory, Research & Practice, 15(3), pp.241-247. Do you have 'shiny object' syndrome? what it is and how to beat it (2017) Entrepreneur. Entrepreneur. Available at: https://www.entrepreneur.com/living/do-you-have-shiny-object-syndrome-what-it-is-and-how-to/288370 (Accessed: February 13, 2023).Episode Notes Contact Mary marywatkinscounselling.co.uk Blackwood Well-being Centre https://www.facebook.com/blackwoodwellbeing Find At The Bench on At The Bench Website At The Bench Tools Website Instagram Our Monday Q & A's YouTube Facebook

On suffering and carelessness.Anonymous (2002). Meditations on the Tarot: A Journey into Christian Hermeticism. New York: Tarcher.Bonifacio Bembo (c. 1450). File:Bembo-Visconti-tarot-arcanum-10-wheel of fortune.jpg, https://tinyurl.com/4zxjhnf8 (wikimedia.org). Accessed February 2023.Aleister Crowley (2004). The Book of Thoth. York Beach, ME: Weiser.Ruth Lawes (2022). This Morning's ‘tone-deaf' energy bills game featured as propaganda on Russian state TV, https://tinyurl.com/5n75dmny (metro.co.uk). Accessed February 2023.Isobel Lewis (2022). This Morning drops Spin to Win energy bill prizes following backlash, https://tinyurl.com/yc4adzrp (independent.co.uk). Accessed February 2023.Support the podcast and access additional content at: https://patreon.com/oeith. Buy me a coffee at https://ko-fi.com/oeith or https://www.buymeacoffee.com/dbarfordG. Or you could send me a lovely book from https://www.amazon.co.uk/hz/wishlist/ls/1IQ3BVWY3L5L5?ref_=wl_share. Hosted on Acast. See acast.com/privacy for more information.

This week on Pharm5: Narcan possibly OTC soon Dexcom G7 now available PBM Transparency Act hearing Rocuronium shortage Phase I Rankings now open Connect with us! Listen to our podcast: Pharm5 Follow us on Twitter: @LizHearnPharmD References: Hoffman J. Narcan is safe to sell over the counter, advisers to the F.D.A. conclude. The New York Times. http://bit.ly/3S2btPf. Published February 15, 2023. Accessed February 16, 2023. Person, Bhanvi Satija PJ. U.S. FDA panel backs OTC opioid overdose drug, proposes label changes. Reuters. http://bit.ly/3xrx0r5. Published February 16, 2023. Accessed February 16, 2023. New Dexcom G7 CGM Nick Jonas Super bowl 2023. Dexcom. http://bit.ly/3Is32cU. Accessed February 16, 2023. Dexcom G7 receives FDA clearance: The most accurate continuous glucose monitoring system cleared in the U.S. Business Wire. https://bit.ly/3UMwMnv. Published December 8, 2022. Accessed February 16, 2022. Bringing transparency and accountability to Pharmacy Benefit Managers. U.S. Senate Committee on Commerce, Science, & Transportation. http://bit.ly/3YAhjKg. Published February 16, 2023. Accessed February 16, 2023. FDA drug shortages. FDA Drug Shortages. http://bit.ly/3Ir1kZb. Accessed February 16, 2023. Drug shortage detail: Rocuronium injection. ASHP. http://bit.ly/3Kat9q3. Accessed February 16, 2023. Schedule of dates. ASHP Match | Schedule. http://bit.ly/3I8MJA7. Published January 19, 2023. Accessed February 16, 2023.

With multiple ways to help habitat reduce invasive species, I think I have found another I would like to try. Using geese sounds awesome for about 30 seconds until you try and herd them. But the seems like a low-key stress-free job I would like to try for a day. Raising geese in small or backyard flocks (no date) Small and backyard poultry. Available at: https://poultry.extension.org/articles/poultry-management/raising-geese-in-small-or-backyard-flocks/ (Accessed: February 10, 2023).       Music from #Uppbeat (free for Creators!): https://uppbeat.io/t/paul-yudin/your-adrenaline License code: QWS1TG5BYTFK2PCL

In the 1930s Harry Powers used several aliases to correspond with lonely women he promised to marry. In 1931 five bodies were discovered on his Quiet Dell, West Virginia farm that was dubbed The Murder Farm.    Want more Southern Mysteries?  Hear the Southern Mysteries show archive of 60+ episodes along with Patron exclusive podcast, Audacious: Tales of American Crime and more when you become a patron of the show. You can immediately access exclusive content now at patreon.com/southernmysteries   Connect   Website: southernmysteries.com Facebook: Southern Mysteries Podcast Twitter: @southernpod_ Instagram: @shannonballard_ Email: southernmysteriespodcast@gmail.com    Episode Sources   Harry F. Powers. Murderpedia. Accessed January 4, 2023. https://murderpedia.org/male.P/p/powers-harry.htm   Hanging the Bluebeard of Quiet Dell. Appalachian History. Accessed January 7, 2023. https://www.appalachianhistory.net/2014/03/grisly-anniversary-hanging-bluebeard-quiet-dell.html   The Bluebeard of Quiet Dell, Clarksburg Serial Killer. West Virginia Gazette. Accessed January 7, 2023 https://web.archive.org/web/20120324101310/http://www.wvgazette.com/mediafiles/document/2009/03/17/Bluebeard_I090317193022.pdf   Harry Powers' Murder Farm. Morbid Tourism. Accessed February 1, 2023. https://www.morbidtourism.com/locations/id/606a1c2bc892bc9da3b0864a   Episode Music Lost by Kevin MacLeod, Licensed under a Creative Commons License; Theme Song “Dark & Troubled” by Pantherburn. Special thanks to Phillip St Ours for permission for use

Ahmad Thomas: A Glimpse Into a Shifting World - Examining the Purpose of Corporate Social Responsibility in a Turbulent Environment Corporate social responsibility (CSR) has become an increasingly important part of business practices. Companies are ostensibly thinking more proactively and creatively about how they can contribute to the world around them and make a positive impact on society. But what does this mean for tech policy in a tumultuous world? In this episode of Tech Policy Leaders, you'll learn from Ahmad Thomas, CEO of the Silicon Valley Leadership Group. After listening to this episode, you'll understand more about: 1. The current state of corporate social responsibility 2. Ahmad Thomas' definition of CSR 3. Why corporations should care about CSR 4. How to implement CSR in your business 5. The benefits of CSR 6. Challenges faced by businesses when implementing CSR Ahmad Thomas Silicon Valley Leadership Group Twitter LinkedIn   Bio  Ahmad Thomas is the CEO of the Silicon Valley Leadership Group, the region's most dynamic business association. As a change agent and next-generation business leader, Thomas partners with the organization's 350+ member companies to promote entrepreneurial solutions to strengthen Silicon Valley business competitiveness, bolster its innovation ecosystem, and create shared economic value throughout the greater Bay Area. Resources The White House. The United States Government. Available at: https://www.whitehouse.gov/briefing-room/statements-releases/2022/08/09/fact-sheet-chips-and-science-act-will-lower-costs-create-jobs-strengthen-supply-chains-and-counter-china/ (Accessed: February 13, 2023)   Inflation reduction act of 2022 (no date) Internal Revenue Service. Available at: https://www.irs.gov/inflation-reduction-act-of-2022 (Accessed: February 13, 2023).   (no date) Broadbandusa. Available at: https://broadbandusa.ntia.doc.gov/news/latest-news/ntias-role-implementing-broadband-provisions-2021-infrastructure-investment-and (Accessed: February 13, 2023).    

This week on Pharm5: Adult Immunization Schedule 2023 Pediatric Immunization Schedule 2023 Rapid acting antidepressant, Zuranolone 2022 NAPLEX/MPJE Pass Rates State of the Union Address Connect with us! Listen to our podcast: Pharm5 Follow us on Twitter: @LizHearnPharmD References: Murthy N, Wodi AP, Cineas S, Ault KA. Recommended Adult Immunization Schedule, United States, 2023. https://doi.org/10.7326/M23-0041. Ann Int Med. 2023. The 5 biggest changes in the 2023 adult vaccine schedules. Medscape. http://bit.ly/40WmmX5. Published February 9, 2023. Accessed February 9, 2023. Committee on Infectious Diseases. Recommended Childhood and Adolescent Immunization Schedule: United States, 2023. https://doi.org/10.1542/peds.2022-061029. Pediatrics. 2023. Swift D. AAP approves 2023 Child and adolescent immunization schedule. Medscape. http://bit.ly/3RMFhPD. Published February 9, 2023. Accessed February 9, 2023. Biogen and Sage Therapeutics announce FDA accepts filing of New Drug Application and grants priority review of Zuranolone in the treatment of major depressive disorder and postpartum depression. Biogen. http://bit.ly/3HR6pbB. Accessed February 9, 2023. Data & Research. National Association of Boards of Pharmacy. http://bit.ly/40W5qQv. Accessed February 9, 2023. Aislinn Antrim E. State of the union address focuses on affordable health care, cost of insulin. Pharmacy Times. http://bit.ly/3jPc4qT. Published February 8, 2023. Accessed February 9, 2023. Full 2023 President Biden State of the Union Annotated and fact checked. CNN. http://bit.ly/3YlJs7w. Accessed February 9, 2023.

Multiple states provide supplemental feed for elk. They do this to reduce the effects of a harsh winter and also to cut down the amount of elk depredation. Wyoming is currently looking to provide a short-term and long-term management plan and to decide whether to continue those feed grounds.   Wy Elk feedground background information (no date) Wyoming Game and Fish Department - Feedgrounds public engagement. Available at: https://wgfd.wyo.gov/Get-Involved/elk-feedgrounds (Accessed: February 7, 2023).     Music from #Uppbeat (free for Creators!): https://uppbeat.io/t/paul-yudin/your-adrenaline License code: QWS1TG5BYTFK2PCL

Random walk theory is that each step is completely random from the previous one. It can help identify variables in wildlife behavior.   Music from #Uppbeat (free for Creators!): https://uppbeat.io/t/paul-yudin/your-adrenaline License code: QWS1TG5BYTFK2PCL   S;, C.E.A.P.M.J.B. (no date) Random walk models in biology, Journal of the Royal Society, Interface. U.S. National Library of Medicine. Available at: https://pubmed.ncbi.nlm.nih.gov/18426776/ (Accessed: February 7, 2023).   Berthelot, G., Saïd, S. and Bansaye, V. (2020) “How to use random walks for modeling the movement of wild animals.” Available at: https://doi.org/10.1101/2020.03.11.986885.    

Since the first invasive insect was identified in 1635 until now, habitat managers have had an uphill battle. With more than 400 invasive insects and over 15 pathogens attacking our forests daily, managers find themselves behind the trying to play catchup.   Music from #Uppbeat (free for Creators!): https://uppbeat.io/t/paul-yudin/your-adrenaline License code: QWS1TG5BYTFK2PCL   Solano, A. et al. (2021) “Firewood transport as a vector of forest pest dispersal in North America: A scoping review,” Journal of Economic Entomology, 114(1), pp. 14–23. Available at: https://doi.org/10.1093/jee/toaa278. Aukema, J.E. et al. (2010) “Historical accumulation of nonindigenous forest pests in the continental United States,” BioScience, 60(11), pp. 886–897. Available at: https://doi.org/10.1525/bio.2010.60.11.5. Forest Service silviculture (no date) Forest Service Shield. Available at: https://www.fs.usda.gov/forestmanagement/vegetation-management/silviculture/index.shtml (Accessed: February 6, 2023).  

What do the Metaverse, blue aliens, and airbenders have in common? They're all based on the idea of the avatar, which goes back thousands of years to the Sanskrit term avatāra. In this episode, we'll explore what an avatar is and how thinking about these ideas in ancient Hindu and Buddhist contexts can help us think about reality, the divine, and even our survival after death. Sounds and Music All music excerpts and soundbites used with an understanding of fair use modification for educational purposes. Theme music by Kevin MacLeod's music https://incompetech.filmmusic.io  Bibliography and Further Reading Clough, Bradley S. “The Ambivalence of the Hindus: The Buddha as Avatāraṇa of Viṣṇu in the Mahhāpurāṇas and Beyond.” The Journal of Hindu Studies (2021): 1–19. Parrinder, Geoffrey. Avatar and Incarnation: The Divine in Human Form in the World's Religions. Oxford: Oneworld Publications, 1997. Sheth, Noel. “Hindu Avatāra and Christian Incarnation: A Comparison.” Philosophy East and West 52, no. 1 (2002): 98–125. Stevenson, Robert W. “The Concept of Avatāra in Ancient and Modern Commentaries on the Bhagavadgītā.” Journal of Studies in the Bhagavad Gītā 3 (1983): 56–86. Vaidya, Anand. Review of Reality+ by David Chalmers in Philosophy East and West, forthcoming. Wolfendale, Jessica. “My avatar, my self: Virtual harm and attachment.” Ethics and Information Technology (2007) 9:111–119. Clips and Sound Effects Watch Mark Zuckerberg Reveal Next-Gen Avatars With Legs!, 2022. https://www.youtube.com/watch?v=njvp-E8gzqA. https://freesound.org/s/403005/ by InspectorJ https://freesound.org/s/326404/ by MorneDelport Avatar | Official Trailer (HD) | 20th Century FOX, 2009. https://www.youtube.com/watch?v=5PSNL1qE6VY. “Avatar: The Last Airbender” Theme Song (HQ) | Episode Opening Credits | Nick Animation, 2016. https://www.youtube.com/watch?v=d1EnW4kn1kg. New Books Network. Raj Balkaran, host. “Podcast | Simon Brodbeck, "Divine Descent and the Four World-Ages In….” Accessed February 2, 2023. https://newbooksnetwork.com/divine-descent-and-the-four-world-ages-in-the-mah%C4%81bh%C4%81rata-or-why-does-the-krsna-avat%C4%81ra-inaugurate-the-worst-yuga. Oxford Centre for Hindu Studies. Ramesh Pattni. “Three Faces of Vedanta: Shankaracharya, Madhvacharya, and Ramanujacharya - YouTube.” Accessed February 3, 2023. https://www.youtube.com/watch?v=tlmdRFz1DVs. New Books Network. Raj Balkaran, host. “Podcast | Sucharita Adluri, "Textual Authority in Classical Indian….” Accessed February 3, 2023. https://newbooksnetwork.com/sucharita-adluri-textual-authority-in-classical-indian-thought-ramanuja-and-the-vishnu-purana-routledge-2014. David Chalmers: Reality+ from the Matrix to the Metaverse, 2022. https://www.youtube.com/watch?v=3ov_BTAsgDU. Little Buddha (1993). Clip via Crescendo on YouTube.com https://www.youtube.com/watch?v=xf4e4tbkmCM Dalai Lama Wants to Be a Machine Avatar, 2011. https://www.youtube.com/watch?v=6JNyUVSoiAE. The Dalai Lama on Why Reincarnation Is Not Important, 2019. https://www.youtube.com/watch?v=uqOMZP6HPP8. DW Shift. How You Can Become Immortal as a Digital Avatar, 2022. https://www.youtube.com/watch?v=X8EiTfOggbI. --- Send in a voice message: https://anchor.fm/malcolm-keating/message Support this podcast: https://anchor.fm/malcolm-keating/support

This week on Pharm5: Walmart, CVS Claim Pharmacist Shortage Changes to Paxlovid, Lagevrio, and COVID vaccines EzriCare eyedrops linked to bacterial outbreak New FDA approvals: Jayprica, Orserdu, Jesduvroq GoodRx sells health info to advertisers Connect with us! Listen to our podcast: Pharm5 Follow us on Twitter: @LizHearnPharmD References: Valinsky J. CVS and Walmart Cut Pharmacy Hours, close some locations earlier, citing staffing shortage | CNN business. CNN. http://bit.ly/3RpgS2F. Published January 27, 2023. Accessed February 2, 2023. Keagy J. American Pharmacists Association on move to cut pharmacy hours. American Pharmacists Association. http://bit.ly/3JB0v0Q. Published January 30, 2023. Accessed February 2, 2023. Paxlovid, Lagevrio prescriptions no longer need a positive COVID-19 test. Becker's Hospital Review. http://bit.ly/3DC3Jh3. Published February 1, 2023. Accessed February 2, 2023. Fact sheet for healthcare providers: emergency use authorization for Paxlovid. New York, NY: Pfizer. https://bit.ly/3RvXNvO. Revised February 1, 2023. Accessed February 2, 2023. Fact sheet for healthcare providers: emergency use authorization for Lagevrio (molnupiravir) capsules). Rahway, NJ: Merck & Co. https://bit.ly/3HsLo72. Revised February 1, 2023. Accessed February 2, 2023. Bulloch M. FDA Advisory Committee vote to simplify covid-19 regimen. Pharmacy Times. http://bit.ly/3jweY3t. Published February 1, 2023. Accessed February 2, 2023. O'Mary L. Bacterial outbreak linked to EzriCare eyedrops: CDC. Medscape. http://bit.ly/3l3tOz9. Published February 1, 2023. Accessed February 2, 2023. Update: Multistate Cluster of VIM- and GES-producing Carbapenem resistant Pseudomonas aeruginosa associated with Artificial Tears. https://bit.ly/3DDHrey. Published January 20, 2023. Accessed February 2, 2023. Center for Drug Evaluation and Research. Novel drug approvals for 2023. U.S. Food and Drug Administration. http://bit.ly/3wO6ckC. Accessed February 2, 2023. Pagliarulo N. FDA approves cancer drugs from Lilly, Menarini. BioPharma Dive. http://bit.ly/3DEgnfc. Published January 30, 2023. Accessed February 2, 2023. FDA approves first oral treatment for anemia caused by chronic kidney disease for adults on dialysis. U.S. Food and Drug Administration. http://bit.ly/3RsL64E. Accessed February 2, 2023. FTC enforcement action to Bar Goodrx from sharing consumers' sensitive health info for advertising. Federal Trade Commission. http://bit.ly/3l50F6C. Published February 1, 2023. Accessed February 2, 2023.

EPISODE NOTES: Every year, one of the biggest parties in the United States takes place in the 300-year-old streets of New Orleans. This episode traces the history of Mardi Gras and its costuming practices in New Orleans up to the twentieth century. Support us at :https://www.patreon.com/historyunhemmedhttps://anchor.fm/historyunhemmed/support Follow us on: Instagram: @history_unhemmed Facebook: History Unhemmed Thank you!

The Imperial Japanese Army was born of, and found its conclusion in, violent conflict. Westernization had come to Japan during the mid to late nineteenth century and divided the nation, for a time reversing the unification efforts of the Tokugawa Shogunate. Consisting of warring clans and provinces governed by a militarily ordered form of government, feudal Japan was a nation designed from warfare, and warfare had long been an essential thread in the weave of Japanese society. You can find the Hardtack Community on all of our socials via our linktree. If you have any feedback on our episodes or suggestions for future episodes, please send us an email: hardtackpod@gmail.com Don't forget to rate us and subscribe! Make your Own Hardtack! Hardtack Recipe (Survival Bread) - Bread Dad Civil War Recipe: Hardtack (1861) – The American Table Sources: Barker, A. J. Japanese Army Handbook 1939-1945. London: Ian Allan Ltd., 1979. Brinkley, Frank and Kikuchi, Dairoku A History of the Japanese People From the Earliest Times to the End of the Meiji Era. Andesite Press, 2015. Clancey, Patrick, ed., TM-3 30-480 Technical Manual Handbook on Japanese Military Forces §. Accessed February 10, 2022. https://www.ibiblio.org/hyperwar/Japan/IJA/HB/HB-7.html?fbclid=IwAR0u_LliAyyGUjGIvNLMTVIBQCiD8LvHzSQ_hUF4eF5yQLNPbxSW4ZPAVas. Drea, Edward J. “In the Army Barracks of Imperial Japan.” Armed Forces & Society 15, no. 3 (1989): 329–48. https://doi.org/10.1177/0095327x8901500301. Drea, Edward J. Japan's Imperial Army: Its Rise and Fall 1853-1945. Read.amazon.com. Kansas City, KS: University Press Kansas, 2009. https://read.amazon.com/?asin=B01EBBK. Paine, S. C. M. The Japanese Empire: Grand Strategy from the Meiji Restoration to the Pacific War. Cambridge: Cambridge University Press, 2017. Smith, Richard J. “Meiji Japan and Late Qing China: Some Comparisons.” Charter Oath IWSM Preface. Accessed January 29, 2022. http://www.ruf.rice.edu/~asia/CharterOathIWSMPreface.html. --- Send in a voice message: https://anchor.fm/hardtackpod/message Support this podcast: https://anchor.fm/hardtackpod/support