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“I think that this is an area that is exploding. Working with drug development, I see new agents all the time, with unique targets I've never heard about, with targets I have heard about used in a different way. So, I really think we're going to see more and more bispecifics. A lot of these drugs are used second line, third line, fourth line. I would not be surprised if they moved up in treatment, especially as we learn safer ways to give these drugs,” ONS member Moe Schwartz, PharmD, BCOP, FHOP, professor of pharmacy practice at the James L. Winkle College of Pharmacy at the University of Cincinnati, OH, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a conversation about bispecific antibodies. Music Credit: “Fireflies and Stardust” by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0 Earn 0.5 contact hours of nursing continuing professional development (NCPD) by listening to the full recording and completing an evaluation at courses.ons.org by October 3, 2026. The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. Learning outcome: Learner will report an increase in knowledge related to the use of bispecific antibodies in the treatment of cancer. Episode Notes Complete this evaluation for free NCPD. ONS Podcast™ episodes: Pharmacology 101 series Episode 275: Bispecific Monoclonal Antibodies in Hematologic Cancers and Solid Tumors Episode 261: CAR T-Cell Therapy for Hematologic Malignancies Requires Education and Navigation Episode 176: Oncologic Emergencies: Cytokine Release Syndrome ONS Voice articles: An Oncology Nurse's Guide to Bispecific Antibodies Bispecific Antibodies Cross-Discipline Cancer Care ONS Voice oncology drug reference sheets: Amivantamab-Vmjw Blinatumomab Epcoritamab-Bysp Glofitamab-Gxbm Mosunetuzumab-Axgb Tebentafusp-Tebn Teclistamab-Cqyv ONS book: Guide to Cancer Immunotherapy (second edition) ONS course: ONS/ONCC® Chemotherapy Immunotherapy Certificate™ Clinical Journal of Oncology Nursing article: Optimizing Transitions of Care in Multiple Myeloma Immunotherapy: Nurse Roles Other ONS resources: Bispecific Antibodies Video Bispecifics Huddle Card Cytokine Release Syndrome Huddle Card Immune Effector Cell–Associated Neurotoxicity Syndrome Huddle Card DailyMed homepage Hematology/Oncology Pharmacy Association late-breaking news article: The Emerging Use of Bispecific Antibodies with Chemotherapy in Diffuse Large B-Cell Lymphoma To discuss the information in this episode with other oncology nurses, visit the ONS communities. To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org Highlights From This Episode “It was 2014 that most of us think of as the beginning of bispecifics in cancer, and that was with approval of blinatumomab. That was granted accelerated approval for the treatment of patients with Philadelphia chromosome–negative relapsed or refractory B-cell precursor acute lymphoblastic leukemia. It is a bispecific that targets CD19-expressing tumor cells and CD3 on T cells. It's the original bispecific T-cell engager and is often called a ‘BiTE.'” TS 2:11 “The term ‘bispecific' means that this is an artificial protein that's developed to hit two different antigens simultaneously. They can be two different epitopes on the same antigen. They can be an antigen on a cancer cell and CD3 on a T cell that kind of recruits the T cell to the cancer. So, there are different types [of bispecific antibodies]. The subtype that we often talk about are bispecific T-cell engagers, which are those bispecifics that do target the T cell. And currently, the target on the T cell that's utilized is the CD3 molecule. That's not the only one that will be used in the future because there's a lot of work being done on other types of T-cell engagers.” TS 4:21 “The targets for lymphoma are CD20. Those are bispecific T-cell engagers that hit CD20 on the lymphoma cell, as well as CD3 on a T cell. ... In myeloma, we have two different targets that have been utilized. One is BCMA or B-cell maturation antigen. That sits on the surface of myeloma cells and on some healthy B cells. ... There's also a target used in myeloma that's called GPRC5D, which stands for G protein–coupled receptor, class C, group 5, member D. ... In small cell lung cancer, there's delta-like ligand 3 (DLL3); it's part of the NOTCH pathway. ... And then this year, we've had a couple agents come out that target HER2.” TS 6:52 “[Toxicities] are very dependent on what your target is. ... The bispecific T-cell engager that's used in myeloma that targets the GPRC5D is also expressed on tissues that produce hard keratin like hair follicles and actually, within the tongue. So the toxicities that we see with that agent are something you wouldn't expect to see if you were using a myeloma agent. You see nail and skin issues. You see taste problems. So it's very specific about the target, which says to me, that every time a new one of these agents comes out, I have to learn about the target that helps me learn about the toxicity. I find that fascinating and really appreciate that.” TS 16:19 “Cytokine release syndrome has been one of the areas that drug development has really focused on to see how they can help mitigate the severity [of it]. ... [One of] the strategies that has been incorporated and studied in clinical trials is the step-up dosing scheme. [It's] where you give initial small doses and over time, increase the dose to the dose you're going to continue with. Usually, monitoring in the hospital is required by the FDA approval for anywhere from 28–48 hours for the first couple of doses. And that's a real common strategy that you'll see. Premedication with H2 blockers, H1 blockers, sometimes steroids. These are also things that are incorporated within the approvals of these drugs and are important to look at.” TS 20:53
Dr. Rahul Banerjee interviews Dr. Ajay Major on patient-reported outcomes, toxicity reporting, and patient engagement in blood cancer clinical trials.
In recognition of World Mental Health Day, we present a powerful and timely conversation with our returning special guest, Beverly Beuermann-King, a seasoned expert in workplace mental health. Beverly shares her insights on two critical threats to workplace safety and well-being today: toxicity in the workplace and the importance of self-care for leaders. She explores real examples of toxic workplaces and offers actionable strategies to help leaders recognize warning signs, communicate effectively, and engage in difficult conversations to address issues head-on. Beverly also unpacks the deeper drivers behind workaholism, sharing how leaders can identify root causes, set healthy boundaries, and intentionally create space to rest, recharge, and reflect, prioritizing self-care to enhance both their own well-being and that of their teams. This episode highlights why mental health isn't just a personal wellness matter; it's a workplace safety issue that fosters a healthier, more resilient workplace culture. Tune in for expert insights to help leaders prevent burnout, navigate toxicity in the workplace, and build environments where people and organizations can truly thrive. About the Guest: Beverly Beuermann-King has over 25 years of experience helping individuals and organizations master their responses to stress, build resilience, and thrive using her innovative S-O-S Principle™. Since founding WorkSmartLiveSmart.com in 1995, she has transformed teams across diverse business sectors. Her presentations, grounded in psychology, sociology, management, and adult education, offer practical strategies to enhance mental health and workplace well-being. She is also a prolific author, respected podcaster, and trusted media spokesperson, with over 500 television and radio appearances. Beverly currently serves as the National President of the Canadian Association of Professional Speakers. Prepare to be captivated as she empowers you to conquer stress, cultivate resilience, and unlock the secrets to a healthier, more fulfilling life. For more information: www.WorkSmartLiveSmart.com Learn more about your ad choices. Visit megaphone.fm/adchoices
Transform your approach to CLL care with insights from clinical pharmacy expert, "Kelsey Marciano, PharmD, BCOP,UCHealth. This podcast unpacks the latest strategies for treatment selection and toxicity management—empowering oncology pharmacists to lead confidently, maximize patient outcomes, and deliver next-level care in the evolving era of oral targeted therapies.
Joshua Ryle brings over two decades of corrections experience to this deeply insightful conversation about the hidden psychological patterns that shape corrections culture. From his early days at the Tennessee Department of Corrections to his current role as a training sergeant, Ryle has observed firsthand how the corrections environment creates behavioral patterns that affect officers both professionally and personally.At the heart of this episode is Ryle's new training program focused on workplace toxicity in corrections. He explains how officers spend their entire workday in a hypervigilant, fight-or-flight state that gradually transforms how they interact with everyone around them. This physiological reality leads to communication challenges, negative filtering, and self-sabotaging behaviors that follow officers home and contribute to concerning wellness statistics in the corrections profession.What makes Ryle's approach unique is his focus on behavioral science and practical solutions. Rather than simply identifying problems, he provides clear strategies for shifting from self-criticism to self-reflection, improving communication despite technological limitations, and creating a culture where colleagues support rather than undermine each other. Ryle's program has gained such recognition that it's now being implemented nationwide through ARC Tactical.Whether you work in corrections or are interested in workplace culture transformation, this episode provides valuable insights into how awareness and intentional behavior change can create healthier environments in even the most challenging professions. Connect with Josh at josh@arttechnet.com to learn more about bringing this training to your agency.Josh's E-mail: josh@arctac.netJosh's phone: 931-624-4444ARC Tactical website: https://www.arctac.net/Send us a text PepperBallFrom crowd control to cell extractions, the PepperBall system is the safe, non-lethal option.OMNIOMNI is cutting-edge software designed to track inmates and assets within your prison or jail. Command PresenceBringing prisons and jails the training they deserve!Disclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Support the showAlso, check out Michael's newest book - POWER SKILLS: Emotional Intelligence and Soft Skills for Correctional Officers, First Responders, and Beyond https://amzn.to/4mBeog5 See Michael's newest Children's Books here: www.CantrellWrites.com Support the show ======================= Contact me: mike@theprisonofficer.com Buy Me a Cup of Coffee https://www.buymeacoffee.com/mikeml Keys to Your New Career: Information and Guidance to Get Hired and Be Successful as a Correctional or Detention Officer https://amzn.to/4g0mSLw Finding Your Purpose: Crafting a Personal Vision Statement to Guide Your Life and Career https://amzn.to/3HV4dUG Take care of each other and Be Safe behind those walls and fences! #prisonofficerpodcast #leadership #podcast @theprisonofficerpodcast Contact us: mike@theprisonofficer.comFacebook: https://www.facebook.com/ThePrisonOfficerTake care of each other and Be Safe behind those walls and fences!
2001 yılında yayınlanan "Toxicity" albümünde yer alan ve System of a Down grubunu dünya çapında şöhrete kavuşturan şarkının ve klibinin hikâyesi.
juniorziegler.com Scripture Reference: 1 Peter 2:13-25
Ever wondered what really happens behind closed boardroom doors when leaders are faced with uncomfortable truths, especially when speaking up could cost them their job? This conversation isn't just about corporate buzzwords or performative change. It's an unfiltered look at how fear quietly shapes decisions, and how a handful of micro-courage moments can actually flip the script for whole organizations. If you think courage at work is all about bold speeches, think again. There's a twist here that might just change the way you see your own leadership, and what's possible for your team. Ready to find out what most leaders are missing (and why it matters now more than ever)? In this episode, you will be able to: Discover how cultivating courage in the workplace can unlock bold decisions that drive real growth and innovation. Learn strategies to overcome fear in leadership that empower you to lead with confidence and authenticity. Build people-first cultures that inspire loyalty, boost morale, and create teams ready to tackle any challenge. Master emotional intelligence and respectful communication to transform workplace relationships and fuel collaboration. My special guests are Kristen Kavanaugh, Mike Randolph Kristen Kavanaugh brings a wealth of real-world leadership experience shaped by roles that truly matter, from her time as Senior Director of Inclusion, Talent, and Learning at Tesla to her service as a Naval Academy graduate and veteran. As Founder and CEO of The Agency Initiative, Kristen focuses on helping leaders and organizations step up with courage, not just when it's easy, but when the pressure is on and the stakes are high. She's also served as Vice Chair for the Department of Defense's first-ever Advisory Committee on Diversity and Inclusion, showing her commitment to building workplaces where everyone can thrive. Mike Randolph is the Co-Founder and COO of The Agency Initiative and a strategic leader with expertise in operational effectiveness and holistic people development. Most recently, Mike held a senior position at YETI, leading and designing Talent Experience programs. Prior to that, he led the Talent Management and Leadership Development organizations at Tesla where he integrated courageous leadership practices into the people systems and programs that accelerated growth. The key moments in this episode are:00:05:17 - Understanding Fear in Leadership and Organizational Culture 00:07:04 - Fear-Based vs Courageous Leadership: Lessons from Tesla 00:10:05 - The Impact of Fear-Based Leadership on Organizations and Society 00:13:11 - The Normalization of Fear and Surveillance in the Workplace 00:15:53 - Leadership Examples Challenging Toxic Normalization 00:17:17 - The Business Case for Protecting Rights and Embracing Diversity 00:19:11 - Leading with Empathy during Crisis and Uncertainty 00:23:02 - The Agency Loop: Courage as the Fuel for Authentic Leadership 00:25:55 - Cultivating Agency, Authenticity, and Growth in Leadership 00:28:00 - Building Courage and Resilience in High-Speed Environments 00:31:00 - Listening to Understand: A Foundation for Authentic DEI Efforts 00:33:00 - Addressing Burnout and Learning Agility in Today's Workforce 00:35:00 - Embracing Curiosity and Courage to Drive Inclusive Leadership 00:38:42 - The Importance of Diverse Leadership Reflecting Customer Needs 00:40:29 - Navigating Cultural Differences and Building Peace at Tesla 00:42:18 - Anchoring Leadership in a Shared Mission to Overcome Conflict 00:44:08 - Courageous Leadership Amid Fear and Toxicity in the Workplace Connect with Kristen Kavanaugh and Mike Randolph Follow on Instagram at @courageoverfearbook, @mikerandolph.official, and @kristenkavanaugh.official for updates and community engagement. Purchase the book at courageoverfearbook.com Learn more about your ad choices. Visit megaphone.fm/adchoices
Ever wondered what really happens behind closed boardroom doors when leaders are faced with uncomfortable truths, especially when speaking up could cost them their job? This conversation isn't just about corporate buzzwords or performative change. It's an unfiltered look at how fear quietly shapes decisions, and how a handful of micro-courage moments can actually flip the script for whole organizations. If you think courage at work is all about bold speeches, think again. There's a twist here that might just change the way you see your own leadership, and what's possible for your team. Ready to find out what most leaders are missing (and why it matters now more than ever)? In this episode, you will be able to: Discover how cultivating courage in the workplace can unlock bold decisions that drive real growth and innovation. Learn strategies to overcome fear in leadership that empower you to lead with confidence and authenticity. Build people-first cultures that inspire loyalty, boost morale, and create teams ready to tackle any challenge. Master emotional intelligence and respectful communication to transform workplace relationships and fuel collaboration. My special guests are Kristen Kavanaugh, Mike Randolph Kristen Kavanaugh brings a wealth of real-world leadership experience shaped by roles that truly matter, from her time as Senior Director of Inclusion, Talent, and Learning at Tesla to her service as a Naval Academy graduate and veteran. As Founder and CEO of The Agency Initiative, Kristen focuses on helping leaders and organizations step up with courage, not just when it's easy, but when the pressure is on and the stakes are high. She's also served as Vice Chair for the Department of Defense's first-ever Advisory Committee on Diversity and Inclusion, showing her commitment to building workplaces where everyone can thrive. Mike Randolph is the Co-Founder and COO of The Agency Initiative and a strategic leader with expertise in operational effectiveness and holistic people development. Most recently, Mike held a senior position at YETI, leading and designing Talent Experience programs. Prior to that, he led the Talent Management and Leadership Development organizations at Tesla where he integrated courageous leadership practices into the people systems and programs that accelerated growth. The key moments in this episode are:00:05:17 - Understanding Fear in Leadership and Organizational Culture 00:07:04 - Fear-Based vs Courageous Leadership: Lessons from Tesla 00:10:05 - The Impact of Fear-Based Leadership on Organizations and Society 00:13:11 - The Normalization of Fear and Surveillance in the Workplace 00:15:53 - Leadership Examples Challenging Toxic Normalization 00:17:17 - The Business Case for Protecting Rights and Embracing Diversity 00:19:11 - Leading with Empathy during Crisis and Uncertainty 00:23:02 - The Agency Loop: Courage as the Fuel for Authentic Leadership 00:25:55 - Cultivating Agency, Authenticity, and Growth in Leadership 00:28:00 - Building Courage and Resilience in High-Speed Environments 00:31:00 - Listening to Understand: A Foundation for Authentic DEI Efforts 00:33:00 - Addressing Burnout and Learning Agility in Today's Workforce 00:35:00 - Embracing Curiosity and Courage to Drive Inclusive Leadership 00:38:42 - The Importance of Diverse Leadership Reflecting Customer Needs 00:40:29 - Navigating Cultural Differences and Building Peace at Tesla 00:42:18 - Anchoring Leadership in a Shared Mission to Overcome Conflict 00:44:08 - Courageous Leadership Amid Fear and Toxicity in the Workplace Connect with Kristen Kavanaugh and Mike Randolph Follow on Instagram at @courageoverfearbook, @mikerandolph.official, and @kristenkavanaugh.official for updates and community engagement. Purchase the book at courageoverfearbook.com Learn more about your ad choices. Visit megaphone.fm/adchoices
About the Guest(s): Dr. Kristin Hieshetter hosts Functional Health Radio, where she shares insights into functional medicine and health optimization. With a background in functional health, she combines her expertise with a passion for educating listeners on preventive health measures. Through her podcast, Dr. Hieshetter aims to empower people with knowledge to make informed health decisions. Episode Summary: In this eye-opening episode of Functional Health Radio, Dr. Hieshetter tackles the pervasive issue of titanium dioxide found in everyday products. She explains the health risks associated with this widely-used chemical, particularly its presence in foods and personal care items. Dr. Hieshetter emphasizes the importance of understanding what we consume and its impact on health, urging her listeners to take a proactive role in avoiding harmful substances. Dr. Hieshetter dives deep into the research regarding titanium dioxide, focusing on its toxic potential and correlation with cancer risk. She shares detailed findings from scientific studies showing how titanium dioxide affects DNA and promotes cancerous growth, especially noting its impact on children's health. SEO keywords such as "titanium dioxide dangers," "cancer risk," and "healthier alternatives" run throughout her analysis, providing listeners with an insightful understanding of this chemical's hazards. Dr. Highshedder stresses the urgent need for regulatory bodies to reassess the safety approvals for titanium dioxide and encourages individuals to be their own health advocates by avoiding products that contain it. Key Takeaways: Titanium Dioxide in Everyday Products: Titanium dioxide is commonly found in products such as toothpaste, candies, sunscreen, and some processed foods, posing potential health risks. Health Concerns and Risks: It has been linked to DNA damage, cancer, and negative impacts on children's health, including anxiety and developmental issues. Regulation and Safety: Despite known dangers, regulatory agencies have been slow to regulate titanium dioxide effectively, which necessitates individual vigilance. Encouragement for Vigilance: Consumers are urged to read product labels carefully and choose products free from titanium dioxide to reduce health risks. Healthier Alternatives: Dr. Highshedder suggests using natural ingredients and making informed food choices to protect one's health and that of their family. Notable Quotes: “Titanium dioxide is a nasty chemical found in many daily products, and it can cause lung cancer when inhaled.” “Animal studies show that nano titanium dioxide crosses the gut-brain barrier and causes paraneoplastic lesions and anxiety.” "Food matters. Everything you put in your body is either immediately going to help you or immediately harm you." "Ingesting titanium dioxide is associated with chronic intestinal inflammation and cancer." "No one thinks that they want to wake up and get cancer. We need to avoid things that deliberately harm." Resources: International Journal of Environmental Research and Public Health: Referenced for a study on the toxicity of titanium dioxide. Journal of Applied Toxicology: Discussed research on liver toxicity related to titanium dioxide. Fictional Book: "Johnson and Johnson, No More Tears" was mentioned to highlight corporate responsibility and cover-up issues (Note: This book is hypothetical in the transcript). Yucca App: Suggested by Dr. Hieshetter to find safe products by scanning in-store items. Engage with the full episode for an in-depth understanding of these critical health insights, and stay tuned for more enlightening content from Functional Health Radio.
In this episode of the ACRO Podcast CURiE Conversations edition, Dr. Jenna Kahn speaks with authors Dr. Scott Silva and med student Caitlin Reichard about their published article, "Dosimetry, Toxicity, and Outcomes of Medically Inoperable Endometrial Cancer Treated With Definitive External Beam Radiation Therapy and Brachytherapy." Contemporary Updates: Radiotherapy Innovation & Evidence (CURiE) is the official publication platform of the American College of Radiation Oncology through the Cureus Journal of Medical Science. Read the full article here: https://www.cureus.com/articles/366834-dosimetry-toxicity-and-outcomes-of-medically-inoperable-endometrial-cancer-treated-with-definitive-external-beam-radiation-therapy-and-brachytherapy#!/
What dose and mode of ingestion of B12 do you recommend for an active 78-year-old husband and wife?If ubiquinol is more bioavailable than CoQ10, what about other supplements with respect to bioavailability?Does proline help ligaments?What are your thoughts on smart watches and EMF exposure?
We're living longer thanks to medical advancesStudy: Does cannabis use increase the risk of diabetes?What dose of selenium and iodine should I take?What do you suggest for people who have carpal tunnel syndrome? I would like to avoid surgeryWhat do you think of the claims made for EDTA? Are there benefits?I have the beginnings of macular degeneration. Is taking the AREDs supplement helpful?
We discuss propofol infusion syndrome (PRIS) and propylene glycol toxicity from lorazepam infusions, with medical toxicologist Dr. Jerry Snow, director of the toxicology fellowship at Banner University Medical Center in Phoenix. Learn more at the Intensive Care Academy! Takeaway lessons
Featuring an interview with Dr Neel Pasricha, including the following topics: Anatomy and physiology of the cornea; intersection of ophthalmology and oncology for patients receiving antibody-drug conjugates (ADCs) (0:00) Association of corneal toxicities with ADCs (4:56) Dose and schedule modifications to mitigate ocular toxicities associated with belantamab mafodotin and other ADCs (9:02) Spectrum and severity of corneal toxicities associated with datopotamab deruxtecan (14:44) Role of optometrists and ophthalmologists in screening for and management of ocular toxicities (17:55) Other ocular toxicities associated with cancer therapies (24:26) Prevention and management of corneal toxicity (33:58) Preexisting ophthalmic conditions as potential risk factors for development of ocular toxicities with ADCs (43:39) General clinical pearls on the management of ocular toxicities with cancer therapies (48:04) CME information and select publications
Dr. Ravi Kamepalli made a startling realization that changed everything: bacteria aren't the enemy. As both an infectious disease specialist and wound care physician, he witnessed firsthand how traditional medicine's war on microbes was failing patients catastrophically. In this profound conversation, he unveils his revolutionary "disease triangles" framework that connects our immune system, lipid metabolism, and microbiome in ways that transform how we understand healing.The statistics he shares will shock you: diabetic foot amputations have a higher five-year mortality rate than breast cancer. While diabetes costs healthcare systems $237 billion annually compared to cancer's $80 billion, we're attacking symptoms instead of root causes. Dr. Kamepalli explains his concept of "energy toxicity" - how excess stored energy triggers inflammatory cascades that turn our own immune systems against us.Through his personal journey of losing 50 pounds and dramatically reducing his LP(a) levels, he demonstrates that supposedly "genetic" markers are actually nutritionally modifiable. His approach integrates metabolic interventions with wound care, using continuous glucose monitoring, food logging, and remote patient tracking to address the underlying metabolic dysfunction that prevents healing.This isn't just about wound care - it's about reimagining medicine itself. Dr. Kamepalli advocates for moving beyond "mass medicine mindset" toward personalized, n-of-one healthcare that empowers patients with tools, tracking, and understanding rather than simply prescribing interventions. His vision extends from revolutionizing American healthcare to building sustainable systems in rural India.BIG IDEA"We cannot kill bacteria and keep the humans alive - we need to learn how to survive together, and that survival depends on fixing our metabolic dysfunction, not declaring war on microbes."Dr. Ravi Kamepalli Contact InfoWebsite: https://nobadbugs.com/Social Media: @WoundPhysicianWebsite: ColigoMed.comSociety for Metabolic Health Practitioners SMHP.orgSend Dr. Ovadia a Text Message. (If you want a response, you must include your contact information.) Dr. Ovadia cannot respond here. To contact his team, please send an email to team@ifixhearts.com Like what you hear? Head over to IFixHearts.com/book to grab a copy of my book, Stay Off My Operating Table. Ready to go deeper? Talk to someone from my team at IFixHearts.com/talk.Stay Off My Operating Table on X: Dr. Ovadia: @iFixHearts Jack Heald: @JackHeald5 Learn more: Stay Off My Operating Table on Amazon Take Dr. Ovadia's metabolic health quiz: iFixHearts Dr. Ovadia's website: Ovadia Heart Health Jack Heald's website: CultYourBrand.com Theme Song : Rage AgainstWritten & Performed by Logan Gritton & Colin Gailey(c) 2016 Mercury Retro RecordingsAny use of this intellectual property for text and data mining or computational analysis including as training material for artificial intelligence systems is strictly prohibited without express written consent from Dr. Philip Ovadia.
Dr Neel Pasricha from the University of California, San Franciso, reviews corneal and other ophthalmic toxicities associated with antibody-drug conjugates and other cancer therapies and strategies for their prevention and management. CME information and select publications here.
Dr Neel Pasricha from the University of California, San Franciso, reviews corneal and other ophthalmic toxicities associated with antibody-drug conjugates and other cancer therapies and strategies for their prevention and management. CME information and select publications here.
Contaminated Site Clean-Up Information (CLU-IN): Internet Seminar Audio Archives
In 2020, ITRC's 1,4-Dioxane team created multiple tools and documents that provide information to assist all interested stakeholders in understanding this contaminant and for making informed, educated decisions. Since the 1950s, 1,4-Dioxane has seen widespread use as a solvent stabilizer. The use of solvents through the 1980s suggests its presence at thousands of solvent sites in the US; however, it is not always a standard compound in typical analytical suites for hazardous waste sites, so it previously was overlooked. The U.S. EPA has classified 1,4-Dioxane as "likely to be carcinogenic to humans." Some states have devised health standards or regulatory guidelines for drinking water and groundwater standards; these are often sub-part per billion values. These low standards present challenges for analysis, characterization, and remediation of 1,4-Dioxane. The 1,4-Dioxane: Science, Characterization & Analysis, and Remediation training is a series of six (6) modules. The six individual modules will be presented together live, and then archived on the ITRC 1,4-Dioxane training webpage for on demand listening. The modular 1,4-Dioxane training series provides an overview of 1,4-Dioxane and presenting six sections from the ITRC guidance document (1,4d-1, 2021):History of Use and Potential Sources (Sect 1)Regulatory Framework (Sect 2)Fate and Transport (Sect 3)Sampling and Analysis (Sect 4)Toxicity and Risk Assessment (Sect 5)Remediation and Treatment Technologies (Sect 6)After the six-part 1,4-Dioxane: Science, Characterization & Analysis, and Remediation series, you should understand:The history of 1,4-Dioxane manufacturing and usage and the potential sources of releases of 1,4-Dioxane to the environment.Primary state and U.S. federal regulatory programs of relevance to 1,4-DioxaneKey physical/chemical properties, and fate and transport processes that are relevant for 1,4-DioxaneBenefits and limitations of the available analytical methodsRisk drivers for human health and how ecological risk comparesHow/when/why different treatment technologies are appropriate We encourage you to use the ITRC 1,4-Dioxane products (14d-1) and these training modules to learn about 1,4-Dioxane and how you can apply these best practices to improve decision-making at your sites. For regulators and other government agency staff, this understanding of 1,4-Dioxane can be incorporated into your own programs. This training summarizes the current understanding of 1,4-Dioxane. While the training makes every effort to keep the information accessible to a wide audience, it is assumed that the participants will have some basic technical understanding of chemistry, environmental sciences, and risk assessment. As with other emerging contaminants, our understanding of 1,4-Dioxane continues to advance. This training provides the participants with information on areas where the science is evolving and where uncertainty persists. To view this archive online or download the slides associated with this seminar, please visit http://www.clu-in.org/conf/itrc/14D-1_091625/
Today we're doing a deep dive into RHOC, where Tamara brought of the ancient drama of Naked Wasted at a lie decector party. We went back and refreshed our memories by watching Naked Wasted (Season 4, Episode 8 if you'd like to do the same) and we have some THOUGHTS! After we explore the toxicity of RHOC we'll dip our toes into the palette cleanser of Real Housewives of Miami and recap our thoughts on their trip to Seville. Plus: Unknown Number, why Bravo is more enjoyable now that we're sober, and our personal experiences with ADHD and OCD minds. Are you craving community in sobriety? Join us in The Sober Mom Life Cafe! You'll get access to 4 weekly peer support meetings, the exclusive Cafe social feed, our monthly book club, the chance to share your story on The Real Sober Moms, and more! Get one week free at this link! The Sober Shift is now available for pre-order! Pre-order now for three free mocktail recipes and access to my pre-order launch Zoom in October. Plus, take a look at my events calendar for a book tour stop near you. I would LOVE to meet you and thank you for being a part of this incredible community! We have two spots open for The Sober Mom Life retreat Oct 23-26th in Scottsdale, AZ! Join us for an incredible sober getaway!https://www.instagram.com/thesobermomlife/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Featuring perspectives from Prof Rebecca A Dent, Dr Hans Lee, Dr Neel Pasricha and Dr Tiffany A Richards, including the following topics: Introduction: The Patient Experience (0:00) Managing Ocular Toxicities Associated with Antibody-Drug Conjugates and Other Cancer Therapies — Dr Pasricha (10:28) Ocular Toxicities in Multiple Myeloma (45:33) Ocular Toxicities in Breast Cancer (50:34) CME information and select publications
Prof Rebecca A Dent from National Cancer Centre Singapore, Dr Hans Lee from Sara Cannon Research Institute in Nashville, Tennessee, Dr Neel Pasricha from the University of California, San Francisco, and Dr Tiffany A Richards from The University of Texas MD Anderson Cancer Center in Houston, discuss strategies to manage ocular toxicities associated with antibody-drug conjugates and other cancer therapies. CME information and select publications here.
Prof Rebecca A Dent from National Cancer Centre Singapore, Dr Hans Lee from Sara Cannon Research Institute in Nashville, Tennessee, Dr Neel Pasricha from the University of California, San Francisco, and Dr Tiffany A Richards from The University of Texas MD Anderson Cancer Center in Houston, discuss strategies to manage ocular toxicities associated with antibody-drug conjugates and other cancer therapies. CME information and select publications here.
What do the acronyms ConVENTID, VENTID and ASS all have in common? Well, have a listen and find out as the boys continue their journey down Highway O2 while avoiding the pitfalls of oxygen Toxicity. Have A Listen!!
We're back with another Britwres indie wrestling special here on the Groupchat Wrestling Podcast — and this one's a big one. TNT Extreme Wrestling have always been close to our hearts (and we're proud to call ourselves sponsors), so when they deliver something special, we want to give it the spotlight it deserves.This bonus episode features an exclusive interview with TNT Ultra X Champion Che Monet, fresh off history-making title defences and heading straight into one of the most talked-about matches of the year: Che Monet vs. Sonny Kiss at Effy's Big Gay Brunch UK at Fusion, Liverpool, on 27 September, as part of a massive double-header! We dive into Che's journey, LGBTQ visibility in wrestling, the pride of carrying TNT gold, and what fans can expect when the bell rings! Sit back, grab a drink, and enjoy a special conversation with one of UK wrestling's brightest champions.00:00 Introduction to the Podcast and Guests01:55 Che Monet's Journey and Competitive Spirit05:06 The Build-Up to Effy's Big Gay Brunch08:06 Reflections on Winning the Ultra X Championship10:58 The Dynamics of Rivalries and Relationships in Wrestling14:04 The Pressure of Representation in Wrestling17:03 The Evolution of Che Monet's Persona19:59 The Impact of First Impressions in Wrestling25:52 The Toxicity of Social Media in Wrestling27:05 Celebrating Local Wrestling and Tag Team Success28:16 The Dynamic of Tag Team Partnerships29:16 The Evolution of Martin Kirby's Wrestling Career31:06 Preparing for Effy's Big Gay Brunch33:37 The Anticipation of a High-Stakes Match35:50 The Importance of Unique Wrestling Personas38:31 The Role of Fan Perception in Wrestling42:47 Musical Inspirations and Entrance Themes47:07 The Evolution of a Wrestling Name53:06 Fun and Games: Rapid Fire Questions55:57 Closing Thoughts and Future Plans
RTL2 Pop-Rock Station l'a annoncé en exclusivité : le groupe mythique de métal alternatif System Of A Down fait son grand retour et jouera au Stade de France le 2 juillet 2026, avec Queens Of The Stone Age et Acid Bath. Pour fêter cette nouvelle attendue depuis neuf ans d'absence en Europe, Marjorie Hache lance l'émission avec un de leurs titres les plus emblématiques : "Toxicity". La suite de l'émission reste tout aussi intense avec le nouveau Nine Inch Nails, puis un hommage à Richard Ashcroft, leader de The Verve, qui fête ses 54 ans avec "Bitter Sweet Symphony". Linkin Park, désormais emmené par Emily Armstrong, impressionne avec "Heavy Is The Crown", et Shame poursuit la mise en avant de son album "Cutthroat", disque de la semaine, avec le tranchant "Screwdriver". Suede revient en grande forme avec "Dancing With Europeans", Wolf Alice dévoile "The Sofa" avant sa tournée française, tandis que Tame Impala révèle un extrait de son futur album "Deadbeat", le percutant "Loser". Hayley Williams (Paramore), en solo, apporte une touche plus introspective avec "Glum", extrait de son projet "Ego Death at a Bachelorette Party". System Of A Down - Toxicity Nine Inch Nails - As Alive As You Need Me To Be The Verve - Bitter Sweet Symphony Sharon Van Etten - Seventeen Linkin Park - Heavy Is The Crown Eric Clapton - Cocaine Black Strobe - I'm A Man Shame - Screwdriver Motörhead - Ace Of Spades CSS - Left Behind Midnight Oil - The Dead Heart Suede - Dancing With The Europeans Thurston Moore - Temptation Inside Your Heart The Vaccines - I Can't Quit The Ting Tings - That's Not My Name Wolf Alice - The Sofa The Seeds - Can't Seem To Make You Mine Cold War Kids - Hang Me Up To Dry Tame Impala - Loser Green Day - Holiday The Undertones - Here Comes The Summer Haylee Williams - Glum The Turtles - Happy Together Franz Ferdinand - (The Dark Of The) Matinée Lorde - Tennis Court Iggy Pop - Lust For Life Jehnny Beth - No Good For People LCD Soundsystem - Dance Yrself CleanHébergé par Audiomeans. Visitez audiomeans.fr/politique-de-confidentialite pour plus d'informations.
The Dad Edge Podcast (formerly The Good Dad Project Podcast)
In this special father-son episode of the Dad Edge Podcast, I sit down with my 19-year-old son, Ethan Hagner, to talk about the ever-evolving world of modern dating, masculinity, and what respect looks like in today's culture. From Snapchat and Bitmoji “vibes” to the dangers of digital footprints, Ethan pulls back the curtain on what Gen Z is really experiencing when it comes to relationships, identity, and self-worth. We get raw and real about breakups, social media drama, posting for “social therapy,” and what red flags look like in 2025. But the conversation goes much deeper than dating. Ethan opens up about his personal growth, past mistakes, and what he'd tell his 16-year-old self—and future daughter—about how to protect your integrity in the world of online relationships and viral opinions. This is a must-listen for any dad raising teens or preteens. It's funny, eye-opening, brutally honest, and packed with generational wisdom from both sides of the table. TIMELINE SUMMARY [0:00] - Welcome to the Dad Edge mission [1:04] - How dating has changed since “back in the day” [2:38] - Meet Ethan Hagner: college, EMT prep, and dad banter [3:58] - Inside the Dad Edge studio & sponsor shoutout (First Form) [5:36] - Ignition + Formula 1 explained: post-workout must-haves [8:08] - Pre-order info: The Pursuit of Legendary Fatherhood [9:11] - How 19-year-olds actually meet people now (Snapchat!) [10:20] - Snapchat's “Quick Add” and Bitmoji-deep dating decisions [14:04] - Dating vs. passing notes in the 90s, how we used to ask friends to “talk to her for me” [16:06] - Red flags on social profiles: vaping, weed, or weird vibes [20:30] - Toxicity, trust, and “the feeling you just can't explain” [24:30] - Social media therapy: breakups that go viral [27:03] - Digital drama and public TikTok crying [30:27] - The real meaning of “game” for Gen Z (hint: not confidence) [32:02] - Confidence vs. bravado: what women really respond to [34:09] - What healthy confidence looks like in teens [35:30] - Are ICks ruining relationships before they start? [39:22] - Ego, lifting, and growing up with the wrong friend group [41:13] - Self-awareness: from wife beater tanks to regretful beliefs [42:35] - Advice Ethan would give his future 16-year-old daughter [43:10] - Digital safety, values, and protecting your future [46:40] - Larry's top two dating lessons for his younger self [47:40] - Regret from not approaching vs. regret from rejection [48:16] - When you strike out, you're still winning [51:11] - Protecting your reputation on social media [52:22] - First Form Dad of the Month: Ty Twizzler's inspiring story 5 KEY TAKEAWAYS 1. Snapchat Changed Dating Forever For Gen Z, Snapchat is the new hallway, lunch table, and dating app combined. But what happens there leaves a permanent digital trail—so teach your kids to tread carefully. 2. Confidence Wins—Ego Repels Bravado might grab attention, but real confidence comes from knowing who you are and not bending for validation. It's quiet, steady, and deeply attractive. 3. Respect Is Never Outdated Whether it's how you treat a teacher, a girlfriend, or yourself, respect is foundational. True character shows when no one's watching—or when everyone's watching online. 4. Your Digital Footprint Never Goes Away Posting relationship drama on TikTok or Snapchat may feel therapeutic in the moment, but it can damage reputations, create enemies, and attract the wrong kind of attention. 5. You're Not Too Young to Lead Ethan may be 19, but his mindset about dating, identity, and future family is already grounded in wisdom. His generation needs more examples like this—and so do ours. LINKS & RESOURCES
This ain't clickbait. This is me, Marie Shadows, talking straight from the heart about wrestling, music, and life without Twitter breathing down my neck.Inside this episode:
I am continue continuing to talk about what toxins are lurking inside your body and today's toxin of the top five that I lab test for and see showing up on a regular basis amongst my clients is cadmium.About the Host:Melissa is an Integrative Health Practitioner helping people get to the root cause of their health issues. Melissa neither diagnoses nor cures but helps bring your body back into balance by helping discover your “toxic load” and then removing the toxins. Melissa offers functional medicine lab testing that helps you “see inside” to know exactly what is going on, and then provides a personalized wellness protocol using natural herbs and supplements. Melissa's business is 100% virtual –the lab tests are mailed directly to your home and she specializes in holding your hand and guiding the way to healing so that you don't have to figure it all out on your own. Melissa has been featured at a number of Health & Wellness Summits, such as the Health, Wealth & Wisdom Summit, The Power To Profit Summit, The Feel Fan-freaking-tas-tic Summit, and the Aim Higher Summit, and has guested on over 30 different podcasts teaching people about the importance of prioritizing our health and how to get get started. www.yourguidedhealthjourney.comLinkedIn: https://www.linkedin.com/in/melissadeally/FB: https://www.facebook.com/GuidedhealthjourneyInstagram: https://www.instagram.com/guidedhealthjourney/Thanks for listening!If you know somebody who would benefit from this message, or would be an awesome addition to our community, please share it using the social media buttons on this page. Do you have some feedback or questions about this episode? Leave a note in the comment section below!Subscribe to the podcast!If you would like to get automatic updates of new podcast episodes, you can subscribe to the podcast app on your mobile device.Leave us a review!We appreciate every bit of feedback to make this a value-adding part of your day. Ratings and reviews from our listeners not only help us improve, but also help others find us in their podcast app. If you have a minute, an honest review on Apple Podcasts/iTunes goes a long way! Thank You!!
What if the very foundation of America was built on a system that was never meant to serve us all? And what if reclaiming something as simple and as profound as our intuition could be the key to creating a more just and loving future? In this episode of HEAL with Kelly Podcast, I sit down with scholar, advocate, and bestselling author Anna Malaika Tubbs to explore the roots of American patriarchy. Drawing from her recent book Erased: What American Patriarchy Has Hidden from Us and her celebrated debut The Three Mothers, Anna reveals how patriarchy was intentionally written into law, how it continues to shape institutions like healthcare and education, and why reclaiming women's intuition is one of the most radical steps we can take toward change. We explore the intentional design of patriarchy in America's laws, and why recognizing that history is often written by those in power is essential to collective healing. Anna highlights the stories of courageous women who have been erased, yet whose contributions have powerfully shaped our nation's evolution. Anna also shares insights on partnership, motherhood, and the ways our relationships and communities can model new ways of sharing power…the path to true democracy. This conversation is both eye-opening and empowering, offering a reminder that because these systems were built, we have the power to build something different. Key Moments You'll Love:
In this conversation, Dr. Jockers sits down with Dr. Paul Savage to explore the hidden roots of chronic inflammation. You'll hear how toxins are the driving force behind today's rise in disease and how plasma exchange therapy is offering people a way to lower their toxic load, calm inflammation, and regain vitality. You'll find out why the usual detox methods like sauna, fasting, and binders don't always cut it anymore. Dr. Savage explains how toxins disrupt nutrient absorption, shut down key pathways, and even damage your body's natural detox systems, making advanced approaches like plasma exchange more necessary than ever. You'll also discover how plasma exchange works, why it's safer and more effective than many other methods, and the kind of real results patients are seeing. From stronger immune systems to clearer thinking and more energy, this episode shows how reducing toxins at the source can change everything. In This Episode: 00:00 Introduction to Plasma Exchange 00:17 Podcast Introduction and Guest Overview 00:46 Understanding Toxins and Detox Strategies 01:48 Introduction to Dr. Paul Savage and MD Lifespan 04:59 Interview with Dr. Paul Savage Begins 05:17 Hidden Sources of Chronic Inflammation 06:48 The Role of Toxins in Chronic Inflammation 08:54 Therapeutic Plasma Exchange Explained 15:32 Functional Medicine Approach to Plasma Exchange 22:55 Patient Selection Criteria 26:23 The Plasma Exchange Procedure 30:54 Clinician Collaboration and Expansion 35:01 Future of Functional and Longevity Medicine 39:43 Final Thoughts and Recommendations Looking for a clean, nutrient-packed snack? Paleo Valley's Grass-Fed Meat Sticks are free from sugar, additives, and preservatives—just pure protein and healthy fats to keep cravings in check and support muscle and immune health. They come in delicious flavors like Original, Garlic Summer Sausage, and Teriyaki, and they're even kid-approved. Try them today and get 15% off your order at paleovalley.com/jockers. Think heartburn comes from too much stomach acid? Think again. Most digestive issues actually stem from too little stomach acid. That's why I recommend Just Thrive Digestive Bitters—they naturally stimulate stomach acid, bile, and enzymes to improve digestion, reduce bloating, and boost nutrient absorption.Save 20% off your order with code JOCKERS at justthrivehealth.com. Support your skin from the inside out with Clearstem, the acne brand that connects internal and external skincare without pore-clogging ingredients. Pair their best-selling Mind Body Skin hormonal acne supplement with Clearstem's clinically effective topicals for results that last. Get 15% off your order today at clearstem.com/drjockers using code DRJOCKERS at checkout. "99.9% of chronic inflammation is driven by toxins. Plasma exchange is a game-changer in detoxing your system." Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio Resources: Get 15% off Paleovalley: paleovalley.com/jockers – Use code JOCKERS Save 20% on Just Thrive: justthrivehealth.com – Use code JOCKERS Get 15% off: https://clearstem.com/drjockers - Use code DRJOCKERS Connect with Dr. Paul Savage: Website: https://mdlifespan.com/ Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https:/www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/
Effective management of adverse events and addressing barriers to care are critical to optimizing outcomes and maintaining quality of life for patients receiving CDK4/6 inhibitors. In this episode, CANCER BUZZ speaks with Julia Lea Ziegengeist, PharmD, BCOP, clinical pharmacist coordinator in solid tumor oncology at Atrium Health Levine Cancer Institute about proactive, team-based strategies to identify, monitor, and manage treatment-related toxicities in patients with early-stage and metastatic HR-positive, HER2-negative breast cancer. Dr. Ziegengeist sheds light on the patient journey, the roles of various multidisciplinary care team members, and useful resources for language and literacy barriers. “I think the biggest thing that is specific to CDK4/6 inhibitors is... eligibility criteria and when we're using the drugs in what setting, having those monitoring protocols and getting that multidisciplinary collaboration is really key.” – Julia Lea Ziegengeist, PharmD, BCOP Julia Lea Ziegengeist, PharmD, BCOP Clinical Pharmacist Coordinator, Solid Tumor Oncology Levine Cancer Institute Atrium Health Charlotte, NC Resources: ACCC Resource: CDK4/6 Inhibitors Management ACCC CDK4/6 Inhibitors Infographic
Carli Davis is a functional sports dietitian who helps active women fuel smarter, prevent burnout (aka REDs), and support hormone health—without fad diets or pseudoscience. A lifelong runner and former collegiate athlete, she's especially passionate about working with endurance athletes, but enjoys helping anyone who values their health and wants to feel their best. Carli began her career in clinical nutrition in 2017, specializing in nutrition support in the ICU and for those undergoing bone marrow transplants. In 2021, she transitioned to preventive health and launched her own private practice in 2024 after relocating to Austin. Her approach is deeply integrative and personalized—combining functional lab testing with root-cause exploration to go beyond the “everything looks normal” response when the body is clearly asking for more. She's on a mission to help women avoid the pitfalls of underfueling and return to a thriving state—where performance, hormone balance, and day-to-day energy align. Carli also values collaboration and often partners with other providers, such as physicians and therapists, to ensure her clients receive well-rounded support. You can connect with Carli or book a free discovery call at https://www.carlirunnutrition.com/ , or check out her popular Meal Planning Guide at https://carli-run-nutrition.kit.com/products/meal-planning-made-easy. In this episode we chat about: Toxicity of running to lose weight Dieting is crushing your performance goals What is RED-s and why you should know about it Why you need to strive to be fertile (even if you don't want a baby) Why carbs are so important Your toxic job is literally killing you Its okay to not train for a race Moving your body shouldn't be your ONLY coping mechanism Why intermittent fasting is trashing your performance Learn more about working with me Shop my masterclasses (learn more in 60-90 minutes than years of dr appointments) Follow me on IG Follow Carli on IG
For freelancers and creatives, surrounding yourself with the right people is critical to staying motivated and inspired. Today's episode dives into the "bad apple effect," how negative influences impact your life and work, and how to remove them to create space for positivity and productivity.OFFICIAL WEBSITE: https://www.filmproproductivity.com/TWITTER: https://twitter.com/FilmProProdPodFACEBOOK: https://www.facebook.com/filmproproductivityCONTACT: https://www.filmproproductivity.com/contactINDIE FILM HUSTLE: https://indiefilmhustle.com/ifh-podcast-network-filmmaking-and-screenwriting/YOUTUBE: https://www.youtube.com/channel/UCqo0Zld2Lm2lJDpDh3GsuZgQUOTES:You are the average of the five people you spend the most time with. Jim RohnSurround yourself with people who lift you higher. Oprah WinfreyDon't let negative and toxic people rent space in your head. Raise the rent and kick them out. Robert TewA rotten apple quickly infects its neighbour. Benjamin FranklinTHIS EPISODE IS SPONSORED BY: -----------------------------------------------------------Please check out my friends shows:FILM FIGHTS WITH FRIENDS PODCASTTHE FILMMAKERS PODCASTTHE HORROR CUTWILDE WORLD-----------------------------------------------------------Thanks:A Himitsu Music: Adventures by A HimitsuCommons — Attribution 3.0 Unported— CC BY 3.0http://creativecommons.org/licenses/b...Music released by Argofox https://www.youtu.be/8BXNwnxaVQEMusic provided by Audio Library https://www.youtu.be/MkNeIUgNPQ8 –––Contact the artist: x.jonaz@gmail.comhttps://www.facebook.com/ahimitsuhttps://www.twitter.com/ahimitsu1https://www.youtube.com/channel/UCgFwu-j5-xNJml2FtTrrB3A
Toxicity is a culture killer. It can be hard to recognize and even harder to change. This happens because people struggle to recognize negative habits in others and themselves. Cultures are built, not found, whether you know it or not. A toxic culture will ruin the professional experience of its people and you have to recognize and address it as soon as possible. The problem is that most people are uncomfortable addressing it because it's a “people thing”. You have to understand others' perspective and be willing to have tough conversations. I have a way of looking at toxicity that is more personal and direct than the average culture advice. Take note of the steps in the process and learn to take them with caution and compassion. Have a great rest of your week.
In this episode of The Collective Perspective, we unpack the hidden cost of holding grudges — and the life-changing freedom that forgiveness brings. Grudges poison our minds, our bodies, and our relationships, keeping us stuck in cycles of negativity and blame. Forgiveness, on the other hand, isn't weakness — it's one of the strongest choices you can make.We talk about how grudges trap us in toxic thinking, how forgiveness shifts our mindset to growth, and how this process is especially powerful for those healing from trauma and PTSD.Are you just going to sit there and dwell on what's wrong — or take back your power, forgive, and move forward?Join Jeff and Travis for practical ways to let go, think positive, and break free from the weight that's holding you down. Listen, share, and take on the challenge: Who do you need to forgive — and how will you start today?#forgiveness #grudges #mentalhealth #positivemindset #healing #ptsdrecovery #emotionalhealth #mindsetshift #personaldevelopment #selfgrowth Chapters (00:00:00) - Introduction: What Makes America Stronger(00:00:26) - Welcome Back: Meet the Hosts(00:00:38) - The Toxicity of Grudges(00:01:30) - The Power of Forgiveness(00:03:30) - Ego and Grudges in Politics(00:06:01) - Personal Stories of Grudges(00:16:28) - Forgiveness vs. Reconciliation(00:18:01) - Practical Ways to Forgive(00:23:05) - Road Rage and Forgiveness(00:24:13) - Conclusion: Final Thoughts and Farewell
Dioxin-like compounds can alter how white blood cells develop and do so in ways that current risk assessment methods fail to predict, according to a study from the Michigan State University Superfund Research Program Center.
Why Minnesota Twins players feel uncomfortable; How did the Twins get here from two years ago; Why the Twins hitting staff faces challenges; Are the Twins going toxic; The dynamics of young players leading the Twins; Plus other Twins talkers with Trevor Plouffe See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Why Minnesota Twins players feel uncomfortable; How did the Twins get here from two years ago; Why the Twins hitting staff faces challenges; Are the Twins going toxic; The dynamics of young players leading the Twins; Plus other Twins talkers with Trevor Plouffe See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Women's health is complicated, isn't it? Between stress, hormones, and all the changes that come with midlife, it can feel like we're constantly trying to put puzzle pieces together without seeing the full picture. That's why I loved sitting down with Dr. Margaret Christensen to talk about what's really going on beneath the surface. She's sharing a perspective on health, intimacy, and connection that every woman deserves to hear. Dr. Margaret walked this journey herself. After facing serious health challenges from toxic mold exposure, she shifted from being a traditional OB-GYN to a leader in functional medicine. Now she helps women uncover the root causes of what's draining their energy, throwing off their hormones, and leaving them feeling disconnected. In our conversation, she opens up about midlife changes, hormone therapy, and how we can reclaim both our vitality and our joy. What really struck me was how she talks about sexuality and connection, not as something to be hidden or ignored, but as a powerful force for healing. We cover everything from navigating menopause to rekindling intimacy to why relationships are so key for our health. If you've ever felt like you're just pushing through midlife instead of thriving in it, this is a conversation you won't want to miss. And if you're ready for a little extra support, I'd love to have you in my 10-day Breeze Through Menopause masterclass, just $17 at dranna.com/breeze. Key Timestamps: [00:00:00] Introduction. [00:03:42] Sacred sexuality discussion. [00:06:03] Spirituality and health connection. [00:08:14] Clinical experience vs. published studies. [00:10:18] Chronic stress and hormonal disruption. [00:14:11] Autoimmunity increase post-COVID. [00:17:51] Post-midlife love story. [00:19:32] Sacred sexuality and body appreciation. [00:23:27] Power of creativity in aging. [00:24:57] Hormone replacement therapy considerations. [00:30:14] Hormonal rewiring during menopause. [00:33:08] Pressure cooker of our lives. [00:35:47] Weight gain and biotoxins. Memorable Quotes: "Sacred sexuality is really honoring our God-given gifts and our bodies." [00:20:54] – Dr. Margaret Christensen "We are energetic beings, we are energetic bodies, everything is made of energy." [00:34:07] – Dr. Margaret Christensen Links Mentioned: 10-Day Masterclass: https://dranna.com/breeze GLP Herbal: http://dranna.com/glpherbal Connect with Dr. Margaret Christensen: Website: https://margaretchristensenmd.com/ Instagram: https://www.instagram.com/drmargaretchristensen/ & https://www.instagram.com/carpathiahealth/ Facebook: https://www.facebook.com/CarpathiaCollaborative Connect with Dr. Anna Cabeca: Website: https://drannacabeca.com/pages/show Instagram: https://www.instagram.com/thegirlfrienddoctor/ YouTube: https://www.youtube.com/@thegirlfrienddoctor TikTok: https://www.tiktok.com/@drannacabeca Produced by Evolved Podcasting: www.evolvedpodcasting.com
An increasing number of case reports have linked turmeric extract supplements to liver injury.
Toxicity is something I've been focusing on more than ever—because it's everywhere. From the water we drink to the air we breathe, the buildings we live and work in, even the everyday products we use—environmental toxins are silently impacting our health at the deepest levels.That's why I'm excited to bring you this powerful conversation with Dr. Kelly McCann—an integrative physician and true pioneer in environmental medicine. Dr. McCann has called environmental toxins the “tsunami” behind today's chronic disease epidemic, and in this episode, she breaks down exactly why.Whether you've been told you're "too sensitive" to chemicals or you've been struggling with chronic symptoms that no one can seem to explain, this episode is a must-listen.Dr. McCann has helped thousands of patients navigate complex medical issues—chronic illness, autoimmune disease, gut dysfunction, hormone imbalances, and more—through compassionate, root-cause-focused care. Her approach blends deep clinical expertise with a calm, healing presence that's helped so many on their path to wellness.In this episode, we explore:Environmental toxicity at the core of the chronic disease crisis & why environmental medicine is the most overlooked component in the functional health arena.The difference between persistent vs non-persistent toxins—and why total load mattersMast Cell Activation Syndrome (MCAS), multiple chemical sensitivity & hidden triggersHow to effectively detox your home and your bodyThe truth about sweating: passive vs active detox, sauna protocols, and what actually worksDr. McCann's clinical insights on binders and supporting sensitive patientsThe crucial connection between antioxidant enzymes and longevityHow environmental toxins interact with gene variants—leading to thicker blood, strokes, and heart attacksConnect with Dr. Kelly McCann:
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Ready to transform your HR operations?Download Deel's free AI-powered HR guide and discover how to streamline processes, stay compliant, and scale globally with ease: https://shorturl.at/Y1ySBWhy do toxic workplaces thrive, and how can leaders turn them around? In this HR L&D Podcast episode, we're sitting down with Dr Mary-Clare Race, a workplace psychologist and leadership expert, to uncover the psychology of toxic cultures and the strategies that transform them into thriving, inclusive environments.From her PhD research to leading DE&I initiatives for companies like Barclays, GSK, and Unilever, Dr Race explains why harmful behaviors persist, how to rebuild belonging, and why empathy, resilience, and self-awareness are the hallmarks of great leadership. She shares practical ways to hold leaders accountable, strengthen workplace connection, and use AI as a tool to support human-centered coaching.Whether you're in HR or lead a team, this conversation delivers actionable insights for creating healthier, more productive workplaces.Dr Mary-Clare Race's LinkedIn: https://www.linkedin.com/in/dr-mary-clare-race-b59a602/Nick Day's LinkedIn: https://www.linkedin.com/in/nickday/Find your ideal candidate with our job vacancy system: https://jgarecruitment.ck.page/919cf6b9eaSign up to the HR L&D Newsletter - https://jgarecruitment.ck.page/23e7b153e7(00:00) Why Human Resources Matter Most (01:46) Introducing Dr Mary-Clare Race (04:00) The Psychology of Workplace Toxicity (06:06) The “Toxic Triangle” Explained (07:48) Turning Toxic Cultures Into Thriving Ones (10:40) Why DE&I Slips During Economic Pressure (13:16) The Backlash Against DE&I (15:12) Building Belonging Through Human Connection (16:45) Remote Work's Impact on Toxicity (18:27) The Connection Crisis at Work (22:19) Do Playground Bullies Become Business Leaders? (26:25) How Early Experiences Shape Leadership Styles (28:56) Empathy, Resilience & Self-Awareness in Leadership (31:46) Micro-Coaching Moments for Busy Leaders (33:30) Leading Multi-Generational Workforces (36:42) Supporting Caregivers and Working Parents (39:26) AI in Coaching and Leadership Development (43:45) Final Advice for HR Leaders
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In today's episode, Dr. Killeen talks about one of the hardest parts of leadership—dealing with toxic team members and the ripple effects they create. From recognizing early warning signs to having honest conversations and setting clear expectations, Addison walks through how to handle negativity with both empathy and decisiveness. If you've ever felt the energy shift in your office or sensed something was off, this episode is for you. Because protecting your culture isn't just important—it's essential.To learn more about Dr. Killeen and his new book, The Shift, or to connect with him, check out www.AddisonKilleen.com.
Join us today for a unique Mormon Stories episode that is the first of its kind. Myndee Tollefson was born in Bountiful, Utah to an orthodox Mormon family. At just 19, she became pregnant and, feeling immense pressure from the Church and her family, gave her baby up for adoption through LDS Family Services—only to later discover that her child's life in the adoptive family was not what the Church promised.Topics include:-Toxicity of purity culture-Unplanned pregnancy in Mormonism-Harsh backlash from her family and LDS community-Adoption within the LDS Family services program-The church's role in facilitating and encouraging adoption-Being a "birth mom"-Troubled teen culture within MormonismHer story sheds light on the emotional and spiritual costs of institutional coercion, and the healing that comes with breaking free from this control. ___________________YouTubeMormon Stories Thanks Our Generous Donors!Help us continue to deliver quality content by becoming a donor today:One-time or recurring donation through DonorboxSupport us on PatreonPayPalVenmoOur Platforms:YouTubePatreonSpotifyApple PodcastsSocial Media:Insta: @mormstoriesTikTok: @mormonstoriespodcastJoin the DiscordContact us:MormonStories@gmail.comPO Box 171085, Salt Lake City, UT 84117
Contributor: Megan Hurley MD Educational Pearls: Acute toxicity of heavy metals: Gastrointestinal upset is the most common presentation Chronic toxicity of heavy metals: Symptoms depend on the metal ingested Increased risk of cancer Altered mentation Developmental delays (in children) Kidney failure Four heavy metals that are tested for in a general panel and their sources: Lead Old paint (homes built before 1977) or some older toys Pipes of older homes or those with corrosive agents May obtain testing kits from home improvement stores to test water supply Mercury Previously in thermometers, although much less common now Compact fluorescent lightbulbs, LCD screens, and some batteries Large predatory fish like tuna, swordfish, dolphins, and shark Arsenic sources Most commonly found in pesticides Contaminated groundwater (especially private wells) Cadmiun sources Most commonly found in tobacco smoke Batteries Metal plating and welding Additional heavy metals that require specific testing Chromium, Nickel, & Thallium Thallium is found in rodenticides, pesticides, and fireworks Management of heavy metal toxicity depends on the intoxicant Generally, chelation therapy is used for acute and severe cases Arsenic: dimercaprol or DMSA Mercury: DMPS (chronic or mild) or DMSA (severe) Lead: succimer is first line, followed by dimercaprol or EDTA References Baker BA, Cassano VA, Murray C; ACOEM Task Force on Arsenic Exposure. Arsenic Exposure, Assessment, Toxicity, Diagnosis, and Management: Guidance for Occupational and Environmental Physicians. J Occup Environ Med. 2018;60(12):e634-e639. doi:10.1097/JOM.0000000000001485 Balali-Mood M, Naseri K, Tahergorabi Z, Khazdair MR, Sadeghi M. Toxic Mechanisms of Five Heavy Metals: Mercury, Lead, Chromium, Cadmium, and Arsenic. Front Pharmacol. 2021;12:643972. Published 2021 Apr 13. doi:10.3389/fphar.2021.643972 Kinally C, Fuller R, Larsen B, Hu H, Lanphear B. A review of lead exposure source attributional studies. Sci Total Environ. 2025;990:179838. doi:10.1016/j.scitotenv.2025.179838 Jannetto PJ, Cowl CT. Elementary Overview of Heavy Metals. Clin Chem. 2023;69(4):336-349. doi:10.1093/clinchem/hvad022 Järup L. Hazards of heavy metal contamination. Br Med Bull. 2003;68:167-182. doi:10.1093/bmb/ldg032 Zhang H, Reynolds M. Cadmium exposure in living organisms: A short review. Sci Total Environ. 2019;678:761-767. doi:10.1016/j.scitotenv.2019.04.395 Summarized & Edited by Jorge Chalit, OMS4 Donate: https://emergencymedicalminute.org/donate/
Some people seem to have a toxic gravitational pull that affects everyone around them. And whether you're with them or not, they are either on your mind or in your space. Getting away from their influence can feel impossible.
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