Podcasts about physiol

Sujet passionnant aujourd'hui, le but est de faire un petit état des lieux de ce que l'on peut trouver comme recommandations basées sur les preuves à propos de la planification de l'entraînement pour l'hypertrophie et/ou la prise de force chez les femmes. On peut vite partir dans des sujets un peu complexes d'endocrinologie du sport mais vous trouverez dans cet épisode des recommandations simples dont tous peuvent tenir compte pour aider les femmes à bien évoluer dans leur discipline. La revue de 61 études : https://journals.lww.com/acsm-essr/fulltext/2024/10000/hormones,_hypertrophy,_and_hype__an.2.aspx Le post de Layne Norton : https://www.instagram.com/reel/DEF7-QkS9nm/?utm_source=ig_web_button_share_sheet&igsh=MzRlODBiNWFlZA==Les effets de la phase du cycle menstruel sur la performance des athlètes d'élite : un examen critique et systématiqueAlice Meignié et al. Physiol avant. 2021.https://pubmed.ncbi.nlm.nih.gov/35122632/https://www.mdpi.com/1056132https://pubmed.ncbi.nlm.nih.gov/32661839/https://pubmed.ncbi.nlm.nih.gov/32456980/https://pubmed.ncbi.nlm.nih.gov/35457332/https://pubmed.ncbi.nlm.nih.gov/32037785/https://pubmed.ncbi.nlm.nih.gov/35320150/Hébergé par Ausha. Visitez ausha.co/politique-de-confidentialite pour plus d'informations.

Acido lattico, dimagrimento localizzato, allenamento a digiuno e carboidrati a cena: quante volte hai sentito parlare di questi temi? Smontiamo cinque tra i falsi miti più comuni su dieta e allenamento, per eliminare credenze errate e costruire un approccio equilibrato e realistico al benessere fisico. Segui Postura Da Paura su Instagram e Facebook per trovare altri consigli e informazioni per vivere una vita più equilibrata e serena. Per noi il movimento è una medicina naturale, visita il sito www.posturadapaura.com per trovare il programma di allenamento più adatto alle tue esigenze. Come promesso ecco le fonti citate durante la puntata: Dupuy O, Douzi W, Theurot D, Bosquet L, Dugué B. An Evidence-Based Approach for Choosing Post-exercise Recovery Techniques to Reduce Markers of Muscle Damage, Soreness, Fatigue, and Inflammation: A Systematic Review With Meta-Analysis. Front. Physiol.. 26 April 2018. https://doi.org/10.3389/fphys.2018.00403 Kerautret Y, DI Rienzo F, Eyssautier C, Guillot A. Selective Effects of Manual Massage and Foam Rolling on Perceived Recovery and Performance: Current Knowledge and Future Directions Toward Robotic Massages. Front. Physiol. 21 December 2020. https://doi.org/10.3389/fphys.2020.598898 Kordi R, Dehghani S, Noormohammadpour P, Rostami M, Mansournia MA. Effect of abdominal resistance exercise on abdominal subcutaneous fat of obese women: a randomized controlled trial using ultrasound imaging assessments. J Manipulative Physiol Ther. 2015 Mar-Apr;38(3):203-9.  Thompson D, Karpe F, Lafontan M, Frayn K. Physical activity and exercise in the regulation of human adipose tissue physiology. Physiol Rev. 2012 Jan;92(1):157-91.  Smith RL, Soeters MR, Wüst RCI, Houtkooper RH. Metabolic Flexibility as an Adaptation to Energy Resources and Requirements in Health and Disease. Endocr Rev. 2018;39(4):489-517. doi:10.1210/er.2017-00211 Doherty R, Madigan S, Warrington G, Ellis J. Sleep and Nutrition Interactions: Implications for Athletes. Nutrients. 2019;11(4):822. Published 2019 Apr 11. doi:10.3390/nu11040822

References Appl. Physiol. Nutr. Metab. 40: 1233–1241 (2015) BMC Biology 2011. 9:85 FEBS J. 2024. May. Volume291, 9.:1870-1885 Haydn, M. 1771. Requiem in C. Moll https://youtu.be/RpS3ZPynlvw?si=pEJueW9E-KTgA8H0 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

References Front. Physiol. 2021. 02. June. Vol.12 Nature Aging 2021. volume 1, pages 60–72 Teleman, JF. 1723 . "Wassermusick" Concerti TWV 55:C3 https://open.spotify.com/album/7cbAYEr4FJf8fAG6upSFgL?si=E_gnKD4QRUuu7xqhSpt9fQ Hayward, J. 1967. "Nights in White Satin" Moody Blues. https://open.spotify.com/track/6L5BZEcZmD6RBJnimzlyKr?si=4d8a0d1e77494b98 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Bentornati su PDPodcast! Iniziamo la seconda stagione esplorando le ragioni per cui ingrassiamo. Analizziamo i fattori che contribuiscono all'aumento di peso e sfatiamo i miti comuni sulla dieta. Impara strategie efficaci per mantenere un peso sano attraverso l'alimentazione e l'esercizio fisico. Segui Postura Da Paura su Instagram e Facebook per trovare altri consigli e informazioni per vivere una vita più equilibrata e serena. Per noi il movimento è una medicina naturale, visita il sito www.posturadapaura.com per trovare il programma di allenamento più adatto alle tue esigenze. Come promesso ecco le fonti citate durante la puntata: M. Takemura, Kikuyaro, Office Sawa, “Biochimica”, GEDI News Network, 2022 Costa Louzada, Maria Laura, et al. “Consumption of ultra-processed foods and obesity in Brazilian adolescents and adults.” Preventive medicine 81 (2015): 9-15. Poti, Jennifer M., Bianca Braga, and Bo Qin. “Ultra-processed food intake and obesity: what really matters for health—processing or nutrient content?.” Current obesity reports 6.4 (2017): 420-431. Myers, Martin G., Michael A. Cowley, and Heike Münzberg. “Mechanisms of leptin action and leptin resistance.” Annu. Rev. Physiol. 70 (2008): 537-556.

In this week's Heal Thy Self episode, I dive into the powerful impact that nature exposure can have on our mental and physical health - even if we just experience it indoors through plants, flowers, natural sounds, and aromas. I'll share fascinating research on how simply viewing roses or plants can increase relaxation and parasympathetic activity while decreasing stress and sympathetic arousal. You'll learn how the scents of certain trees and plants, like hinoki cypress and cedars, can boost immune function and natural killer cell activity while lowering stress hormones like adrenaline. I'll also reveal the unexpected benefits of listening to birdsong and nature sounds on improving focus, sleep quality, mood, and even cardiovascular health. Get ready for easy "exposure hacks" you can use to radically enhance your indoor environment and well-being. === Puori https://puori.com/drg and use code DRG for 20% off the already discounted subscription prices.  Molly's Suds https://mollyssuds.com/drg and use code DRG for 20% off === References: -Park S.-H., Mattson R.H. Therapeutic Influences of Plants in Hospital Rooms on Surgical Recovery. HortScience. 2009;44:102–105. doi: 10.21273/HORTSCI.44.1.102. -Ulrich R.S. View through a Window May Influence Recovery from Surgery. Science. 1984;224:420–421. doi: 10.1126/science.6143402. -Li Q, Kobayashi M, Wakayama Y, et al. Effect of phytoncide from trees on human natural killer cell function. Int J Immunopathol Pharmacol. 2009;22(4):951-959. -Ikei H, Song C, Miyazaki Y. Physiological effect of olfactory stimulation by Hinoki cypress (Chamaecyparis obtusa) leaf oil. J Physiol Anthropol. 2015;34(1):44. -Ikei H., Komatsu M., Song C., Himoro E., Miyazaki Y. The physiological and psychological relaxing effects of viewing rose flowers in office workers. J. Physiol. Anthropol. 2014 doi: 10.1186/1880-6805-33-6. -Ikei H., Song C., Igarashi M., Namekawa T., Miyazaki Y. Physiological and psychological relaxing effects of visual stimulation with foliage plants in high school students. Adv. Hortic. Sci. 2014;28:111–116.

Sen jest niezbędnym elementem naszego życia. Bez niego ciężko sobie wyobrazić dobre samopoczucie i zdrowie. Jednak coraz więcej osób zgłasza problemy z długością i jakością snu. Dlaczego tak się dzieje? Jakie konsekwencje mogą mieć zaburzenia snu? Ile godzin powinniśmy spać? I czy da się zmierzyć jakość snu? Na te i inne pytania odpowiemy w dzisiejszym odcinku. Moim dzisiejszym gościem jest dr n. med. Joanna Ludwikowska – specjalistka Radiologii i Diagnostyki Obrazowej oraz certyfikowany lekarzem Medycyny Stylu Życia amerykańskiego International Board of Lifestyle Medicine. Warto dodać, że jest pierwszym radiologiem w Polsce z tym tytułem. Jej misją jest pokazanie ścieżki do zdrowia, energii oraz równowagi psychicznej i fizycznej w oparciu o dowody naukowe. W pracy z podopiecznymi łączy 12-letnie doświadczenie kliniczne lekarza medycyny z wiedzą opartą na 6 filarach zmiany w medycynie stylu życia. Asię znajdziecie na instagramie pod nickiem @dr_joanka oraz stronie internetowej: www.drjoanka.pl Odcinek podcastu jest wspierany przez markę Kogen, która czerpie inspirację z japońskiej filozofii troski o zdrowie oraz łączy naturę z osiągnięciami nauki. Marka Kogen tworzy zaawansowane nutraceutyki, które skutecznie wspierają organizm w radzeniu sobie z wyzwaniami współczesnego życia. Z kodem DRKARABIN otrzymasz 10% zniżki na produkty w sklepie Kogen: https://kogen.pl/sklep/ Lista publikacji o których wspominamy w podcaście: Grandner MA, Hale L, Moore M, Patel NP. Mortality associated with short sleep duration: the evidence, the possible mechanisms, and the future. Sleep Med Rev. 2010;14(3):191-203. Cappuccio F.P. i wsp. Sleep duration and all-cause mortality: a systematic review and meta-analysis of prospective studies. Sleep 2010 May;33(5):585-92. Garbarino S. i wsp. Role of sleep deprivation in immune-related disease risk and outcomes. Commun Biol. 2021 Nov 18;4(1):1304. Caliandro R. i wsp. Social Jetlag and Related Risks for Human Health: A Timely Review. Nutrients. 2021 Dec; 13(12): 4543 Gottlieb D.J. i wsp. Sleep deficiency and motor vehicle crash risk in the general population: a prospective cohort study. BMC Med. 2018 Mar 20;16(1):44 Pastukhov, Y.F.; Ekimova, I.V.; Khudik, K.A.; Guzhova, I.V. Protein 70 KDa in the Control of Sleep and Thermoregulation. J. Evol. Biochem. Physiol. 2008, 44, 74–81. Ito T, Maeda T, Goto K, Miura T, Wakame K, Nishioka H, Sato A. Enzyme-treated asparagus extract promotes expression of heat shock protein and exerts antistress effects. J Food Sci. 2014 Mar;79(3):H413-9 Ito T, Goto K, Takanari J, Miura T, Wakame K, Nishioka H, Tanaka A, Nishihira J. Effects of enzyme-treated asparagus extract on heat shock protein 70, stress indices, and sleep in healthy adult men. J Nutr Sci Vitaminol (Tokyo). 2014;60(4):283-90 Takanari J, Nakahigashi J, Sato A, Waki H, Miyazaki S, Uebaba K, Hisajima T. Effect of Enzyme-Treated Asparagus Extract (ETAS) on Psychological Stress in Healthy Individuals. J Nutr Sci Vitaminol (Tokyo). 2016;62(3):198-205. Robinson C.H. i wsp. The relationship between duration and quality of sleep and upper respiratory tract infections: a systematic review. Fam Pract. 2021 Nov 24;38(6):802-810. Harding, E. C. i wsp. The temperature dependence of sleep. Frontiers in Neuroscience 2019, 13, 336. 0:00 Intro 0:37 - Wstęp 2:48 - Czy sen jest tematem mocno niedocenianym? 3:48 - Po co nam sen? 7:08 - Biologiczne funkcje snu 9:19 - Następstwa zdrowotne zaburzeń snu 12:16 - Jak wpływa na nas zbyt długi sen? 15:44 - Jak brak snu wpływa na choroby neurodegeneracyjne? 18:49 - Dlaczego w obecnych czasach trudno nam wyspać się? 25:42 - Jak światło niebieskie wpływa na nasz sen? 28:21 - Jakie choroby mogą zaburzać sen? 31:09 - Jak powinien wyglądać prawidłowy sen? 35:12 - Zaburzona relacja ze snem 38:32 - Jak zbadać jakość snu? 39:58 - Co zrobić, by dobrze się wysypiać? 48:11 - Suplementacja na lepszy sen

This past May I was invited to schedule a time to appear on a podcast entitled “A Little Less Fear”. The title intrigued me as you can imagine. As I learned about the host, Lino Martinez, I found that not only did I want to appear on his podcast but that I was certain he would be a wonderful guest here on Unstoppable Mindset. As it turned out, I will be appearing on his podcast later in August and we just today, August 2, 2023, recorded my episode with Lino, (pronounced Leeno). What a fascinating and heart wrenching story Lino has to tell. He was born in 1980. While a diagnosis wasn't forthcoming until he was 36 years old, Lino was born with Muckle Wells Syndrome. As he will tell us, this syndrome manifests itself as the various parts of his body were at war with each other. He did attend school around many illnesses due to the syndrome. However, things grew worse in 2006 and he began what turned out to be some forty surgeries. Even through the surgeries he worked to secure a doctorate in Psychology. He is a college professor today and has learned to thrive. I believe you will find that Lino has much to tell us about how we can learn to fear less by especially learning more about self love. I am going to leave it to him to explain. Our conversation this episode is far ranging and quite provocative in a good way. I hope you find many good take-aways from my time with Lino Martinez. Be sure to check out his podcast “A Little Less Fear” too. About the Guest: Lino Martinez, Psy.D, is in the forefront of his life for the first time as a man. At birth he was given a rare genetic disease, Muckle Wells Syndrome, in which he was diagnosed 36 years later. In just 12 years, from ages 26-38, Lino had gone through over 40 surgeries to maintain his life. Lino was also born female and transitioned from female to male, to better match his authentic self at age 34. Lino is now 43 years strong and thriving for the first time in his life. With incredible health experts, and a strong will to survive, Lino was able to take his pain and create a fruitful life with it. He now lives as vibrant as possible, walking on two legs, with his doctorate in Clinical Psychology. His dissertation explored ways to help women suffering with Chronic Urological Conditions by using Existentialism and providing a model for a therapeutic setting. Some of his greatest passions are writing poetry, singing, interviewing people on his podcast show and showing love to the world. He is also inspired by the Deaf community and aspires to connect the hearing world and the Deaf world. Lino wishes to help the suffering world through telling his story, and writing to help the world be a peaceful, loving place for humanity. With his new book, A Little Less Fear, Lino hopes to encourage others to live by his motto of living life with more love. Ways to connect with Rob: www.alittlelessfear.com https://www.instagram.com/alittlelessfearpodcast/ https://www.youtube.com/channel/UCtP4TN79CnanTFpRfOw0lUA https://www.tiktok.com/@alittlelessfear?lang=en https://www.linkedin.com/in/dr-lino-martinez-48ba83202/ About the Host: Michael Hingson is a New York Times best-selling author, international lecturer, and Chief Vision Officer for accessiBe. Michael, blind since birth, survived the 9/11 attacks with the help of his guide dog Roselle. This story is the subject of his best-selling book, Thunder Dog. Michael gives over 100 presentations around the world each year speaking to influential groups such as Exxon Mobile, AT&T, Federal Express, Scripps College, Rutgers University, Children's Hospital, and the American Red Cross just to name a few. He is Ambassador for the National Braille Literacy Campaign for the National Federation of the Blind and also serves as Ambassador for the American Humane Association's 2012 Hero Dog Awards. https://michaelhingson.com https://www.facebook.com/michael.hingson.author.speaker/ https://twitter.com/mhingson https://www.youtube.com/user/mhingson https://www.linkedin.com/in/michaelhingson/ accessiBe Links https://accessibe.com/ https://www.youtube.com/c/accessiBe https://www.linkedin.com/company/accessibe/mycompany/ https://www.facebook.com/accessibe/ Thanks for listening! Thanks so much for listening to our podcast! If you enjoyed this episode and think that others could benefit from listening, please share it using the social media buttons on this page. Do you have some feedback or questions about this episode? Leave a comment in the section below! Subscribe to the podcast If you would like to get automatic updates of new podcast episodes, you can subscribe to the podcast on Apple Podcasts or Stitcher. You can also subscribe in your favorite podcast app. Leave us an Apple Podcasts review Ratings and reviews from our listeners are extremely valuable to us and greatly appreciated. They help our podcast rank higher on Apple Podcasts, which exposes our show to more awesome listeners like you. If you have a minute, please leave an honest review on Apple Podcasts. Transcription Notes **Michael Hingson ** 00:00 Access Cast and accessiBe Initiative presents Unstoppable Mindset. The podcast where inclusion, diversity and the unexpected meet. Hi, I'm Michael Hingson, Chief Vision Officer for accessiBe and the author of the number one New York Times bestselling book, Thunder dog, the story of a blind man, his guide dog and the triumph of trust. Thanks for joining me on my podcast as we explore our own blinding fears of inclusion unacceptance and our resistance to change. We will discover the idea that no matter the situation, or the people we encounter, our own fears, and prejudices often are our strongest barriers to moving forward. The unstoppable mindset podcast is sponsored by accessiBe, that's a c c e s s i  capital B e. Visit www.accessibe.com to learn how you can make your website accessible for persons with disabilities. And to help make the internet fully inclusive by the year 2025. Glad you dropped by we're happy to meet you and to have you here with us. **Michael Hingson ** 01:21 Well, hi, and here we are once again with another episode of unstoppable mindset. We're inclusion diversity in the unexpected meet. And in case you really don't know the reason the subtitle is that way is that when we talk about diversity, very rarely does anyone ever talk about disabilities. So I put inclusion first because if people say they're inclusive, they can't get away with leaving out disabilities. How's that for a philosophical attitude. But anyway, there we are today, we have as a guest, Lino Martinez, who is a really neat person I've gotten to know over the past few months and we've chatted a little bit more today. And he has an interesting story to tell for a lot of reasons. And I'm gonna let him do most of it. And I'm gonna sit back and listen and just but if I really need to, so leave it all. I want to welcome you to unstoppable mindset. Thanks for being here. **Lino Martinez ** 02:14 Thank you for inviting me. It's such an honor. Thank you so much. **Michael Hingson ** 02:17 Well, I really appreciate you coming and, and I know you and I are going to do an episode of your podcast called a little less fear later in the month. So that'll be fun. So we'll have to talk about that. But why don't you start by telling us about kind of the early you and kind of where you came from. And I'm really interested to hear more about this Michael's wells muckle wells syndrome. I've never heard of it before, but I'll leave you tell it in your way. **Lino Martinez ** 02:44 Okay, thank you so much. So yeah, basically, let's see here. Uh, well, I was born in East Los Angeles in January of 1980. And I was born two months early, as an emergency C section, baby for my mother, the cord was wrapped around my neck. Now, I used to joke about this. And I used to see, well, I looked like I was trying to hang myself commit suicide in the womb, because I knew what I signed up for. I didn't really want to be born. But I mean, lo and behold it. I mean, I really I was born early and and shortly after I was born. Within six months, I started having health, health issues, a lot of body spasms, a lot of tummy aches, and I was in and out of hospitals ever since I was a little kid. So, but the way that the disease presented itself was a lack of me growing, I wasn't thriving at all, I was very skinny little kid, and I'm very tiny petite. And it just, I had severe stomach pains. And I was always in the hospitals. And that's really how I spent a lot of my life. And, and it really wasn't until, until I was 36 years old, where they finally diagnosed me with a rare genetic disease. I'm not sure if you want me to jump from birth to 36 years old, because a lot happened in between all of that. But to make the long story short, that what the disease does is it causes inflammation throughout my entire body. Now all diseases inflammation, even even having a headache is an inflammation. But this disease specifically has a mutation in the genetic mutation called an L and L RP three genetic mutation. And so when that is activated, it kind of like it kind of like it causes a war with all parts of my body, every organ, every nerve. And so when there's constant inflammation in the body, and your nerves and your organs, things start to dysfunction, and they start to overreact. One of the doctors said that the disease is a drama queen. So **Michael Hingson ** 04:49 quite literally, love doctors with great medical descriptions. But but it really probably makes sense. Yeah, **Lino Martinez ** 04:56 so let's say that and it could be triggered by anything. It can be triggered by stress, it can be triggered by any emotional stress, physical stress, even an injury, anything can cause this disease to activate and it can present itself and in countless ways, from migraine headaches to paralysis. And so in my case, since it took so many years to diagnose, it lead to paralysis and paralysis and my motor nerves and my peripheral nerves. And the paralysis began in my pelvic area. And basically, I wasn't able to pee, I wasn't able to go pee like a normal person does, starting as early as 26 years old. And by the time doctors figured out what was going on, that my muscles weren't working at, there's a lot of inflammation in the bladder that the bladder was hardening. By that time, there was no salvaging of my my bladder. And so after about 15 surgeries, it was not salvageable. And by the time I was 33 years old, I had a complete what's called a radical cystectomy, which is a complete removal of my urinary bladder. And they did a complete reconstruction using about 60 inches total of my small intestine, my appendix and removing my urethra and cutting my kidney tubes in which took about five years to heal. So it was quite an adventure. And there's a lot of suffering involved in that, but I came out on the other side stronger than ever. **Michael Hingson ** 06:30 Wow. So you, you just really wanted to get the attention to the doctors, right. **Lino Martinez ** 06:37 I guess. I was a challenge. I'll tell you that much. It was a big challenge for them. It **Michael Hingson ** 06:42 certainly sounds like it well. So what was it like for those first 26 years going through, obviously having a lot of issues. And so I'm like you, you clearly went to school and other things like that. So tell me a little about that. **Lino Martinez ** 06:55 So by the time I was 26, I had my master's in psychology and my bachelor's in communication. I was doing very well. I do have my doctorate in clinical psychology, and I graduated when I was 30. That was back in 2010. I'm 43. Now, you graduated **Michael Hingson ** 07:09 with what in 2008? Doctorate in clinical doctrine? Wow. **Lino Martinez ** 07:13 Yeah, back in 2010. But from the first 26 years, yes, I was definitely going to school or getting a lot of good grades. But I was also sick in between. So I was constantly going to doctor appointments, and they couldn't find anything, quote unquote, wrong with me at the time, but I knew there was something going on. There was something different than that. And I could just feel it. I could just feel that it wasn't your average person. Yeah. Yeah. Well, **Michael Hingson ** 07:35 where did you go to college? So **Lino Martinez ** 07:39 yeah, I got my bachelor's at Cal State San Bernardino, and mass communication. And I got my master's at the Chicago school. And I also got my doctorate at the Chicago School of Professional Psychology, the Los Angeles campus. Well, **Michael Hingson ** 07:52 and as you pointed out earlier, we should tell people you're in what Pasadena now so you're really not all that far from us. Just a hoot and holler away. **Lino Martinez ** 08:02 Yeah, I'm in Pasadena, California. Lovely. Sunny Pasadena. Yeah. And it is today. So you can call it the heat is on Michael. The heat is on. This is **Michael Hingson ** 08:10 August 2 When we're doing this recording, and it was 95 out here today. **Lino Martinez ** 08:16 Oh, yeah. Yeah. So we're getting over here to Wow. But **Michael Hingson ** 08:21 you see you, you know, it seems like 30 as an age to get your doctorate that is certainly not by any standard, unusual, and been so good for you to go off and do that. **Lino Martinez ** 08:34 Thank you. I appreciate that. **Michael Hingson ** 08:35 Did you start up practice or what? **Lino Martinez ** 08:37 I was unable to practice, I was unable to get licensed because I started having a lot of surgeries prior prior to graduating. Luckily, the faculty and all of the professors worked with me while I was in hospitals, in and out of hospitals, I was able to complete my dissertation, within years of after graduating. And it was from the time that I graduated to about 40 years old that I had over 40 surgeries to save my life. And so I even missed the whole Facebook era. I never even had a Facebook I still don't because that was very popular back then. And I was too busy wired up to machines and tubes coming out of my body. So I also had a feeding tube for eight years and I also lost my voice my ability to speak for two and a half years. I also wear hearing aids. So the journey continued with this with this disease up until I was approved approved by my insurance for immunosuppressant medications. And when I finally got on immunosuppressant medications, my voice started to come back very slowly, one vocal cord at a time. And yeah, so here I am thriving finally. **Michael Hingson ** 09:38 Well, you certainly sound like you are and you're you're hopefully done with the surgeries for a while. **Lino Martinez ** 09:43 The last surgery I had was about six months ago and it was because I had a CT scan of my kidneys and they thought they saw some stones but when they went in there, they didn't find anything. So luckily I really feel that I'm for reals this time. I'm going to live the rest of my life disease free. That **Michael Hingson ** 10:03 is so cool. And you are clearly a person who sounds very positive about all of it. And you get here, it really did. So any other things that you want to talk about regarding medical issues and all that. **Lino Martinez ** 10:21 Be honest with you, it was very challenging losing my voice. I mean, losing my bladder was was a challenge in itself, but losing my voice, because I also saved my chin when I was a teenage singer. And so when I all of a sudden couldn't speak, and even hurt, my vocal cords even breathe because your vocal cords expand when you breathe. So even breathing hurt. So I was really bedridden for that amount of time. But I went to sign school to learn sign language, because I wasn't going to give up I have to keep communicating somehow. But that time, I became very depressed. So I went from physical ailments to now hitting my mental health. And I hit my mental health because I thought, What am I supposed to do with my life, I lost my ability to pee, I have a feeding tube, I can't speak, I'm losing my hearing. I'm worrying trifocals on my glasses, like I don't, I don't know what else is gonna go next. And it seems like every every Oregon was going I went, I was on high doses of heart medications for a incredible rapid heart rate. So I was really bedridden for a very long time. And I wasn't sure if I was going to make it. But one thing that I do want to reveal is that I'm transgender, I lived the first 34 years of my life as a female. And I also knew at the time that if I didn't transition, I was going to die in the wrong body. And I was going to die in authentically. And so when I decided to finally get on hormone, hormonal replacement therapy, other things started to align even my purpose in life. So when I was in this, what I call the dying stages, because this disease was taking my life very slowly, I looked on the brighter side and saw that now my gender was aligning with what felt the best alignment for my spirit in this life. And that was a masculine energy. And even though at the time, I didn't have a voice, and I didn't know what I would even sound like as a man because part of becoming a man was being able to sound like a man. And now wasn't even going to sound like a man. But at least I was looking like one. And at least I was feeling like one. And so when I was getting into this alignment of my feeling masculine other things started to align because I started to experience more self love. And when I experienced more self love, other joys started opening and opening itself to me and presenting itself as different avenues in my life. **Michael Hingson ** 12:33 Did becoming a man, though, in any way, medically, help the whole healing process and getting you through a lot of the surgeries or lessening them. Did anything become simpler or is it wasn't really totally unrelated, **Lino Martinez ** 12:47 it became simpler became simpler, because I was more authentic with myself. It's kind of like, it's kind of like this, this is the only way I could explain it. Let's see that you. Somebody tells you hey, Michael, just for the next three years of your life, you're going to be called Jane, wherever you go, your name is Jane. Now you know, you feel like Michael, and you feel like my your body feels like Michael, you can feel yourself as Michael. But all of a sudden you have to be Jane for the next three years. So being Jane for the next three years is not going to feel authentic to you. And in that you start to present yourself differently in a different manner. And you start to feel insecure. So I lived my life with such insecurity. So when I finally transitioned to my full self, there was less insecurity and with less insecurity means there's less fear. And when there's less fear, that means there's more love. And when there's more love, there's more opportunity. **Michael Hingson ** 13:39 And with all of that there's a whole lot less stress and that had to help in the healing process. Physiologically, yeah, physiologically, did it make life easier just to be a man instead of a woman? Or did that did that help just from a standpoint of apps actual physiological sorts of things did did the insides of your body becoming a male as opposed to a female make any difference? **Lino Martinez ** 14:08 The what made a major difference is that I decided to have a lot of surgeries to better align my body physically as a man and I wasn't intimidated at all because by by now Michael, I had had over 2030 surgeries to save my life. So what it's not a big deal to have my breasts removed at this point, it's not a big deal to have a hysterectomy and it really wasn't and I'm sorry for for listeners that are listening for the first time and if it triggers them, for me to say that it was nothing to have a double mastectomy or that it was nothing to have a hysterectomy. This isn't in any way to hurt anybody's experiences with whatever they may have experienced. But for me personally it was freedom. For me personally, it was not painful. There was joy involved with that. And it better align with me when I touched my chest and the breasts were gone. It felt like this is me whole this is who I am. Well, **Michael Hingson ** 14:53 the other part about it is just listening to you clearly you're very confident about yourself Today, and as I said, with all the things that have happened a whole lot less stress, and that has to help the confidence we I'm actually writing we're we're in the middle of writing a book about fear. And the idea behind it basically, is that the biggest problem with fear is everyone thinks you can't control it. It's all biological. And that's all there is to it. But the reality is, you have control over fear or can learn to control fear so that you can make it a very powerful tool, as opposed to a negative thing in your life. And, of course, my story of being in the World Trade Center on September 11, and the things that I learned that prepared me, although I didn't know it at the time, but prepared me to be able to deal with the emergency of what happened that day and getting out and so on, was all about creating a mindset that I only later realized that creative which was fear, is not really the problem. There are some things you can control and some things that you can't. And what we need to focus on are the things that we can and one of them is really the whole issue of fear. We don't need to be afraid of everything, even unexpected things that happen in our lives. If we prepare. **Lino Martinez ** 16:17 Yes. And a lot of the times it's hard to prepare to not be in fear, because our instincts and as you were saying a lot Physiol physiologically, our body will respond with increased cortisol levels stress hormones, when fear presents itself, but fear in general as an emotion, is the complete opposite of love. And in life, there's only two emotions fear and love. Because all negativity is the derivative of any negative feeling of any negative thought is fear. And so when you can break that down and see, well, why am I feeling negative about this? What's the underlying fear? There's a fear with every negative emotion, there's an attachment to it. And when you see that life is only two major emotions, love and fear, you can start leaning more towards love. And when you start leaning more towards love, there's less fear and less negativity. **Michael Hingson ** 17:10 Yeah. And that makes a lot of sense. It's just that we don't teach that collectively to people we **Lino Martinez ** 17:19 don't, we don't. And that's challenging. And when we learn that in school, either, yeah, we don't know that anywhere live, we **Michael Hingson ** 17:27 don't live anywhere. Well, and look at all the things that are going on around us. If you sit back and analyze everything that's going on in politics, it's all about fear. People are selling fear. And they're, they're not helping to encourage us to step back and look at things or on television, advertisements are oftentimes all about fear, really is beware of your car light, or engineering light or your your car. Motor light coming on, you know, so get this warranty now. And it's all about fear. **Lino Martinez ** 18:04 It really is. It's all about fear. And I really stay away from politics as much as possible. I don't listen to the news, if I really try to remain as focused in the present moment, because any any any politics or anything that's going to steer someone towards fear. It's either living in the past or living in the future. And it's not living currently right now. Like right and right, specifically right now with you and I chatting, Michael, there is no fear right now. He's only connection and because of couldn't reconnecting because of the love for humanity. **Michael Hingson ** 18:35 I do watch the news every day. But I do it because I want to know what's going on in the world. And I can do that. Without fear. I've, I've learned I've read enough to understand the need for conversation to understand the need to connect. And so for me, what is just amazing is how many people have forgotten how to do that. I mean, but I grew up needing to connect. And I was taught how to do that by my parents. And I think that's extremely important. And I wish that we taught it more today than we do. **Lino Martinez ** 19:09 I love that you can do that. Michael, I think I'm not in a place in my life where I can listen to negativity, negative news, and then it not come with me and kind of start steering me in a negative in any direction. So I that's where I'm at right now. And mostly because my mother, I'll give you an example. My mother watches the news every day. And she's so she gets in that negative loop. She'll be like, Oh, don't do this, because this or there, oh, there's this killer going around, or you're this and this might happen. And I just I have to tell her sometimes I get very short temper and I say you know what, you need to stop watching the news. So that really scares me away from watching and if she if she was able to deviate from from not being so absorbed about it, and I saw more of the positive aspects of it. I probably would watch it or listen to it a little more. But for me personally, I tried to see your way as far as I can **Michael Hingson ** 19:59 I fully understand that. And for me, as I said, it's it's a source of information. But if I start letting it get to me, whatever it is, then that's the time not to watch it anymore. And very frankly, I love having a good part of the day where there's there's nothing going on my wife passed away last November after we were married for 40 years. So it's me in the house. And I have a person who helps part time. But I value silence. And I think that we really need to value and get more of that. Because, again, if we don't have that silence, then we don't spend any time thinking and becoming analytical and really reflecting on our lives and what we need to do to improve and so on. I **Lino Martinez ** 20:51 agree with you. I love being in silence myself, and I do it very often. **Michael Hingson ** 20:55 Yeah, it's, it's valuable to do, we don't always need to have something going on. And and you know, I will have something on I'll have I collect old radio shows as a hobby. And I also listen to internet stations that do radio when I listen to other things as well. But if if I'm going to have something on, it's going to be reading a book or listening to old radio shows, and I will watch news for a little bit during the day. But it's not something that is a major driving force that I have to do. And certainly I'm not going to let it affect me. But I have control over that. I have control over whether I let it affect me or not. Which is the point? **Lino Martinez ** 21:35 Definitely. That is the point. Exactly. Yeah. **Michael Hingson ** 21:39 So it really works. works out well, I think. I hope so anyway. So does does fear, however talking about fear like that does fear serve a purpose. **Lino Martinez ** 21:54 I believe that fear steers you in the direction of what needs healing and what needs attention. And it really depends also on the type of fear, if it's a fear of something of being attacked of your wellbeing, perhaps that's more of an intuition for safety. And if it is, but if it is a fear based on emotions, that can be a really good indicator of things that need attention to, for example, Shadow Work, or things that need to be released. Things that need attention in order for you to progress yourself as a mind, body and soul in this one human life that we're experiencing. So fear definitely has a purpose. Well, **Michael Hingson ** 22:36 and if you're afraid of something, like fear of being attacked, and so on, it really is important to spend a little bit of time looking at why do I feel that way? And that's what most of us don't? Do we just live in the fear rather than living in the real cause? Or what can be the real result. We don't look at that. **Lino Martinez ** 23:04 I love what you said that why do I feel this way? This? I mean, not that many people ask themselves a question, as you said, they just live in reaction. **Michael Hingson ** 23:10 Yeah, it's all about reaction, isn't it? It is it really, it really is. And it's it's unfortunately, getting a lot worse. We're getting a lot more reactive and things that we do look at drivers today. I am absolutely ready for the time. Some of your people are going to hate me for it. But I am absolutely ready for the time when we have fully operating and running. Well, autonomous vehicles because I think it's high time to get the hint driving out of the hands of drivers. **Lino Martinez ** 23:37 That's coming soon. coming very soon. Yeah, it's **Michael Hingson ** 23:41 gonna come pretty soon. It'll take a little while yet, but drivers are just not being responsible at all. And I've been in the car with many people who are driving and they complain about people on the road and people who have the road people who just pass them I was in a vehicle going to an airport. And all of a sudden this motorcycle actually, I guess it was only one past past us and the the driver said I cannot believe what just happened. We were in a lane. There was a car next to us. And this motorcycle threaded its way through and the driver said there had to be no more than an inch on either side. But he was in a hurry. And he passed us on he was really moving quickly and pass us I'm going to give me a break. Why? Yeah, **Lino Martinez ** 24:28 the rage. Something anyway, impatient in this. **Michael Hingson ** 24:33 Yeah. And it happens all too often. Well, how did you get into this whole idea of thinking a lot about fear and making that kind of a basic part of what you do and what you think about and what you practice in psychiatry psychology. **Lino Martinez ** 24:51 Well, the reason I got into fear was because of my fear whether or not I was going to live with this genetic disease whether or not I was going to make it and I realized that I had fears, constant fears, fears of the female that I was fears that I wasn't being authentic fears that I had this disease that I was going to die young everything was fear, fear, fear, fear, fear. And every time I overcame an obstacle, AKA a fear, I realized, oh, one less fear, or one less fear, one less fear. And every time there was a less fear I had, I started to gain a momentum of more happiness and more joy, and more in realizing that there actually is a way to succeed in life. And I don't mean a diploma, I mean, to succeed in life into finding growth, personal growth, expansion and opportunity within yourself. **Michael Hingson ** 25:39 And so you, you have made that a mainstay of a lot of the things that you do, needless to say, Oh, **Lino Martinez ** 25:46 yeah. And then even even recently, is going through somewhat of a separation with my girlfriend, we're looking a little separated mode right now. And even in the separation mode, a lot of fears that I wasn't faced with before were coming up, it's been about a month. And these fears that I haven't been faced with ever. Because before, when I separated with somebody, I think maybe the type of separation that I had before I it was just a different period of my life. And in this period of my life, I started to feel, having these emotional fears that I hadn't experienced before such as I'm unlovable or I'm not deserving of love. Or where did these fears coming from? Why am I feeling these things? That's not true. These are untrue. All these fears that we tell ourselves, none of it's true. We're all deserving and we're all worthy of love. So where do these fears come from? So I've been digging into a lot of these fears and how I'm feeling and trying to break through them, get past them, so that I can continue to grow on on the path that I was before the relationship, but it's really posing a lot of obstacles in which I am overcoming because today I can smile. And two days ago, I couldn't. So yeah, it's fears present themselves in many different ways, shapes and forms. **Michael Hingson ** 27:05 How do you work through it? How do you how do you work yourself to get beyond some of those fears? **Lino Martinez ** 27:13 Well, I write a lot. And I think a lot and I meditate a lot. And I write a lot of poetry. And in my poetry, I can give you an example. Poetry really helps me and I can read to one of my poems here. It helps me discover what is inside me, and what I'm fearing and what what it where is there light. So a poem that I wrote last night it says, The dim night lights up with the full moon ready for a fresh start and a new beginning, emerging after a rebirth was necessary. And I still feel the heat of your breath on my skin, the way our love emerged after an Eclipse of the Heart. So when I write it releases, fears, it releases stagnant energy within my body, and I'm able to then see things in a different type of light, and also meditating. I mean, I do spend a lot of alone time I do take a lot of baths. And in this alone time with baths I symptoms, I listened to meditative hertz frequency music to heal myself. And I do self affirmations starting with the I am statements I am love, I am worthy. I am deserving and then moving up from after I am I feel I feel worthy, I feel loving I feel deserving. Moving up from feel you go with I do statements I do believe that I am worthy. I do believe that I am love moving up from I do too I love I love myself I love unconditionally means note when you love unconditionally, Michael, that means that you love with no with no conditions involved meaning that you simply just love for loving, it's because love is not a transaction. So I go with I love my mother I love myself, I love my friends. I love this bathtub. I love right now. After I love I move up to my throat chakra and the throat chakra is the speaking that I speak. And so when I say I speak words of love, I speak words of unconditional love, I speak of worthiness I speak deserving. After that I go to I see I see love all around me, I see happiness all around me I see joy. Then after that I go to understand, I understand I understand that I am deserving. I understand that I am love. I understand that I'm unconditional love. I understand that I can give the same love to everybody else that I give to myself. And so when I when I move up my body with all of these statements, it brings me into an alignment and realizing that I'm okay, I'm okay and I'm going to be okay. **Michael Hingson ** 29:49 And none of that is conceived at any way. I mean, there's nothing wrong with loving yourself and loving other people. As long as If you are truly loving, I mean are plenty of people around who are conceited. I'm the greatest thing in the world. There's a difference in saying I'm the greatest thing in the world and believing it from a philosophical standpoint. Yeah, it's just amazing how, oftentimes we miss some of the very things that you're talking about, which I think is great that you're able to go through that process. And really love and respect yourself and come out the other side better, much better for it. Absolutely, **Lino Martinez ** 30:32 yeah. Because if somebody comes with the, with the attitude of I'm the greatest thing in the world, there is still there's actually some fear attached to that not love. You're saying you're the greatest thing of the world, that means that you aren't any lower than anybody else. And there's somebody saying they're not lower than anybody else, they're already having fear that they could potentially be lower than someone else. And if that were to happen, they wouldn't be the greatest thing in the world. So when it comes from true love, there's no judgment attached to it. When you just say I'm unconditional love, I means I love myself without any conditions. And in doing that, I can see everybody for who they are without any conditions. **Michael Hingson ** 31:07 Right? And that's the real point. Isn't it? Unconditional? Exactly, **Lino Martinez ** 31:12 exactly. Because when it's not unconditional, you're trying to control the situation so that it matches what's going to make you happy. And in that case, it ends up being manipulative. **Michael Hingson ** 31:21 Have you ever read a book called it's a little book, The greatest thing in the world is Love by Henry Drummond? No, but I gotta get this. He's a British philosopher. And he was a, I think he was with a group. And they asked him to talk about I forget how it started, I think they asked him to talk about love. And he, he took a Bible and and he read a couple of lines from Ephesians, and so on. And basically what he did, was lectured for about 15 or 20 minutes, and it got written into this book. And there are other lectures in there as well. But that love is the greatest thing in the world. And there is a lot of evidence to prove that. And the people who truly love and who truly are willing to love are going to be the ones who recognize that first, as long as they live by it. Of course, he talks about God, and that's fine. Because that's all part of it. Because that's where the love originally comes from. **Lino Martinez ** 32:28 Exactly. Yeah. And you know that, that sounds amazing. It sounds like a little book that I'm gonna have to definitely, yeah, I think also right now, you mentioned God, I think that a lot of people steer away from when they hear God because they think that God is a human being rather than an energy, rather than a force of energy. So when I think of God, I think of the universe I think of higher consciousness, I think of all that unites us, because we're all universally connected, and we can all communicate telepathically and we do. And that is where the true essence of God lies, higher consciousness. **Michael Hingson ** 33:05 And we're all part of it. And it is all part of us, God is part of us. And we are we are, we are all part of the same thing. And it's so unfortunate that we, we miss that a lot of organized religion tends to not really teach some of those things. And I went to a church and attended for years. And the pastor said, you know, people are at this church are really great at knowing about spirituality, you've they can intellectually talk about it. But as far as being spiritual as far as really having that true, emotional relationship with God, they don't. I **Lino Martinez ** 33:49 agree with you. And that is because of organized religion that is more of a control factor, rather than rather than free will. **Michael Hingson ** 33:57 Yeah. I hope that that somewhere on the line, we can get beyond some of that. And I think we will. I don't know what it will take Michael. Go ahead. **Lino Martinez ** 34:09 I feel it's headed that way. Yeah, we'll get there. Yeah, because what I've noticed, mostly on social media, actually, well, there's a lot of almost said the word kids, but I'm gonna say kids, because people in there, like it. If I see people in their 20s to eat, I mean, to me, they're very young and but these young minded individuals in their 20s I'm noticing a very spiritual and a lot more spiritual than I was in my 20s. I wasn't spiritual at all. I didn't I wouldn't God, what are you talking about? God, I'm not I'm going to hell, I'm a sinner. These people. Yeah, they're not thinking like this anymore. I'm seeing the evolution happen. And so it's an evolution and it's really beautiful. **Michael Hingson ** 34:49 It is and I think it will continue. I think that people are and young people are going to be leading the way are discovering that there's a whole lot more to The world then all this hatred, and I hope, it won't take overly long for some of those people to get into positions to stop some of the nonsense that we see all around us. I was fortunate my, my father was very spiritually oriented. And we had a lot of conversations about God. When I was growing up, I did some with my mother, but my dad was really the one. And he was a great thinker about a lot of those things. So I was blessed by having someone who encouraged having strong relationships in terms of loving myself, but loving God and recognizing that God is in all of us and what God is. I **Lino Martinez ** 35:42 love that. Yeah, it's really important to have these discussions with with your children definitely helps them open up and feel things differently and expand their mind and not close up their heart or, or their mind **Michael Hingson ** 35:54 what we've talked about a little bit, but maybe you could define a little bit more detail, what really is self loves. Since we know it's not being conceited, and all that stuff. **Lino Martinez ** 36:06 It's a really good question. So self love can look different to everybody. My personal experience, self love came from accepting who I am, and who I've become and who I am becoming. And also comes from forgiveness, forgiving your past forgiving past pains, and learning lessons. And when you can learn the lesson and forgive the pain forgive the past. You gain love, and you gain joy. And self love is also joy. When you find what brings you joy, what makes you laugh, what helps you connect with other people. That's all self love. Self love is also spending time with yourself alone time, or even talking to yourself, doing things that you love to do not what other people love to do, but you yourself, what do you love to do. And also telling yourself, you love yourself. And this can be really difficult, especially if you're having a bad day. And I can tell you because I had many bad days last month after this separation. But I keep at it, Michael, I'll keep at it. And I'll keep telling me so before I go to bed, I love you lino, I love you. And even if I say with tears, or a knot in my throat, I'll still keep adding, I'll keep telling myself because I know that inside I am loved and that God loves me. And if God loves me, why wouldn't I love me. And so it's just a constant reminder, a constant push, that we are made, we're made to love. We're here in this in this life, to love ourselves, and to give the same love to others. So self love can look as as beautiful as learning how to grow within, as even eating something that you love, or even learning something new, a new activity, doing something healthy for yourself. Even the people that you hang out with, who are you hanging out with self love looks like hanging out with people, that increases your peace. If people are not bringing you peace, it's probably time to move around, move that energy around, refocus on who brings you peace and what's going to bring you peace. And when you start bringing peace to yourself, peace will start navigating towards you naturally. **Michael Hingson ** 38:13 I liked the way you you put that and that you talked about peace because we we oftentimes go down these rabbit holes and we don't come back to wait, what's going on? I'm not feeling peace. I'm not feeling confident, or I'm not feeling certain. Why is that? And going back to recognizing what it was like yesterday when I did feel all of those things. I **Lino Martinez ** 38:39 love how you said that. Again, asking yourself these questions is so important to be asking yourself these questions because you will get an answer a lot. Oh, you don't. And then there you go. And you know what, Michael? That's self love right there. Self love is asking yourself questions. Start a relationship with yourself, I can tell the audience's if you have not done this yourself, and you don't know where to start. You can start by having conversations with yourself sitting in a quiet space and seeing what comes through the what kind of answers comes to your mind when you ask yourself these questions. That's spending time with yourself quality time with yourself. And that's self love as well. **Michael Hingson ** 39:11 I love to tell people that. You know why. As I mentioned earlier, my wife passed this past November after 40 years of marriage. And as I tell people if I misbehave I know I'm going to hear about it. So I have to stay on the straight and narrow you know, leave it for two years and marriage is a great thing and I still value everything that we had and as far as I am concerned really do have. So I know that if I misbehave in some horrible way I'm gonna hear about it somewhere along the line. I'm sure you will. That's all I need. So you know, I'm not going to say I'm living in fear because of it. But, you know, it's it really is love because I know what we had and why we had it. and maintaining that mindset is really so important. **Lino Martinez ** 40:04 It really is my thank you for sharing. So **Michael Hingson ** 40:06 you talked about people talking with themselves and really interacting with themselves. What other advice can you give to help someone who maybe wants to start really learning more about themselves. **Lino Martinez ** 40:23 If somebody wants to learn more about themselves and doesn't know how to start, where to start, I do I do recommend journaling. And I know it sounds cliche, but it's it helps so many people helps millions, billions of people to journal even if you're not a good writer, you don't have to be a good writer. If you're you can even speak it in your notes. You don't have to write you could just speak it in in your phone and just kind of keep a memorandum is that the right word? memorandum? That's fine. Sure it works of of your personal journey and start asking yourself questions, start giving yourself the opportunities to for different choices and things in your life. What have you been interested in your life that you haven't done yet? Well, you know what, I really, I want to take this road trip here. I've never done that before. Okay, well, let's, let's put this let's write this down. Let's talk about this. What is this road trip feel like? Well, what would it signify for me, oh, that I stepped out of my comfort zone, that I was able to be exploratory that I was able to see different a different path and meet new people. And perhaps maybe even now, I want to move to a different city, because I travel I mean, there's just so much expansion when you start coming up with these ideas within yourself. And so I would first start with journaling, because so much comes out of it. When you start to journal and talk to yourself and ask yourself questions and come up with these ideas. Creativity will be your guide, creativity will be your North Star, your navigation tool. And we all have an inner navigation star, we all have this north star within us. And it wants us it wants to navigate us, we just have to ask, we have to ask it's as easy as asking. **Michael Hingson ** 41:52 Well, and I think that the whole issue of journaling also means go back and read it. And and think about what what you've written to. **Lino Martinez ** 42:07 Exactly. I've left myself a lot of memo notes as well. voice notes, and I'll go back and and listen to this Oh, today, I wanted to do well. But you know what, actually, Michael, what I did last night, I was cleaning out my office. And I found some notes of some things that I wanted to accomplish this year. And that's another thing that I can recommend for people as well getting to know yourself and getting to know what you want to do. Give yourself some and you know, I try not to say the word goals, because there tends to be a lot of negativity with gold, what if you don't reach your goal, there might be some fear in that. So rather than reaching a goal, just write yourself stuff that you want to do and make it sound that easy stuff that I want to do. And if you don't do it, that's fine, because it's just stuff. But either way, if you get the stuff done, and you can go back and reflect and say, Hey, I did that stuff. It felt great. And so I was able to go back and say, Wow, so far, it's been six months into the year and I've done this stuff. And so far, I feel great that I've done this stuff, or that I completed this task. And so yeah, make it fun, have fun with it. **Michael Hingson ** 43:06 The other side of it. And the other aspect that's worth considering is you took some notes, you wanted to do this stuff. And you look at them in six months, you didn't do some stuff is also scared to go. Why didn't I do that stuff? **Lino Martinez ** 43:22 Yeah, right. Yes. **Michael Hingson ** 43:25 And it doesn't necessarily have as you said, I mean, it's a bad thing that you didn't, but why didn't you? Were you afraid? Or was there really something else that came up, that was a more important bunch of stuff to do, which is also just as Okay, now, I understand the whole concept of the issues with goals. So just writing down direction and writing down ideas that you want to do is fine goals, that there there's a place for goals and things that you have to do. But a lot of things aren't goals. And so it is it is a fair thing to then say, why didn't I do that? **Lino Martinez ** 44:01 You know why like that as well. Because why didn't I do that can lead you all kinds of different directions? It could You could even say, Hey, I never really even wanted to do that. I didn't really want to do that, I guess. And you can even figure out if that's something that you want to revisit and whether or not you want to try it again or just let it go. **Michael Hingson ** 44:18 Try it gives you a discussion point, which is what it's really all about, is I think really the issue, right? So there's nothing there's nothing wrong with discussing and you can talk to yourself. And as you said you will get answers. Yeah, that's the other part about it. I think and it goes back to talking about God. You know, we talk about prayer a lot. Churches talk about prayer a lot. But the reality is God knows what we want. It isn't so much that we have to tell God what we want, because God knows, but verbalizing it or putting it in some form for us. The other aspect of that is listening I'm looking for the response. And it may not come exactly what in the way that we think or how we think. But we should be looking for a response. And I say pretty much invariably, we'll get the response somewhere. **Lino Martinez ** 45:15 The response definitely comes to us. And if and one thing that I've learned too, is to not obsess over getting an answer, right, when you start to obsess over getting an answer, you create a resistance. And resistance holds up a lot of energy in your space. And when this resistance is holding up a lot of filling up your space with with tangled energy, you're disallowing what's supposed to come to you naturally. And so part of this is releasing a lot of a lot of resistance. And that that can be challenging as well. **Michael Hingson ** 45:47 There is something to the old adage of watched pot never boils. Just Just sing. So I've learned that when I turned my tea kettle on in the morning, don't stand there and wait for it to boil, go do other things. And when it boils, you'll hear **Lino Martinez ** 46:07 yes, absolutely. I love that. But **Michael Hingson ** 46:11 there is something to be said for that. What is really is **Lino Martinez ** 46:15 what a struggle taught you. struggle has taught me has taught me a lot, Michael. So when I was struggling and come again, I mean, I'm still in some struggle, struggling in some certain emotional parts of my life right now. And because just what I'm kind of just overcoming right now. But the struggle for me, when I did think of struggling before was me struggling physically in pain. But one thing that I learned and this is because I practice Buddhism for for about five years, and our monk taught us that just because you're struggling or because you're suffering, it doesn't mean you have to be in pain. And when I when when he said that it really struck a beautiful chord within me. And it made me realize that hey, you know what, that's my body is suffering, I am in pain, I do feel this, but but I don't have to be in pain overall. Overall, I can think happy thoughts. Overall, there's connection all around me. Overall, if I sit here within my with my true self, my inner being, I'm okay. And I'm going to be okay. And when you start to see and the the the eyes of seeing it, when you start to look at pain as an opportunity to transform pain into wisdom and love, you start to see that anything can be transformed. And so that is really what I learned with struggles struggle with struggling with a lot of pain and realizing that pain can be transformed, because pain is just energy. And all energy be can be transformed. And energy is not either positive or negative. It's neutral. And so if I can transform it into something beautiful, wise and into love, why not choose the latter? **Michael Hingson ** 47:56 Yeah. There's, there's no reason not to do that. You know, there's there's physical pain. And of course, as doctors and others tell us, pain is a warning, there's a message about something with your body. But even that is a subset of the more general spiritual or emotional pain that we do have the ability to deal with. **Lino Martinez ** 48:21 Right? Absolutely. **Michael Hingson ** 48:22 Which is so cool. Well, you've talked about the fact that you value silence and so on what is silence taught you. **Lino Martinez ** 48:32 So my value from being silent, came from when I lost my voice for almost three years. And at first, it was very difficult. But I accepted that there was there was a chance that I would never speak again. And when I accepted that, I started to go inward more and see more of within my own life, my own personality, my own wants and desires. And that's really where the beauty started to blossom. It's almost as if my higher self said, Hey, I'm going to shut you up and you're going to be completely silent in order for you to go inside, within and really find the beauty within yourself. And once that silent really taught me to calm down, ease anxiety, be patient, and just allow things to unfold naturally. And that's what silence teaches me even now when I am in silence, learn to appreciate the moment the solitude and allow the universe to naturally show you and unfold things for you because everything's happening in a synchronistic manner. **Michael Hingson ** 49:39 So you've been going through the whole business of having a relationship and it's kind of stopped for a while and I don't know whether that's that's permanent or not. But what what have you learned from that and also having silence again in your life like that? **Lino Martinez ** 49:56 That's a beautiful, beautiful question. Honest See, I really feel that I'm meant to be with this woman. And what for whatever reasons whether it's trauma, whether it's insecurities that caused us to be in this non-communicative. I guess the buzzword is ghost being ghosted. But I do feel that we have a really strong spiritual connection and that what we had was was very authentic. It was very soulful, spiritual, very loving, and whatever the separation means right now, at the moment, I can tell you right now that it means growth. Because I have grown so much in this last month going inward and going silent, I have meditated more than I ever have. I've taken more walks than I ever have. I've taken more baths by myself listening to meditative music than I ever have. And I was able to, in this just last month, really ask myself, where my fears were stemming from what if I never hear from her again? What does that mean? And again, asking those questions, Michael, what does that mean, right away, the fear will start to start to show up that I'm unlovable or I'm undeserving, but none of that's true. But when did this support this originate? You don't where it originated, and that I realized is growing up with alcoholic family. And growing up with an alcoholic family, parents are not usually present when that happens when when they're drunk. So as a kid, I didn't really fully have present parents emotionally. And so when somebody ghosts me, it started to remind me of my childhood when family members would ignore me because they were busy hitting the bottle rather than paying attention to their kid. And I started to realize this isn't the same situation. And this isn't true. And so in going that, I constantly have to rewind and say, and rewire my brain, and even go back to that timeline, and forgive myself for my survival skills that I that I had to go through in order to survive emotionally, and mentally as a little kid, and really gravitate towards learning how to feel safe within myself and not receiving the love that I needed as a little kid. But I so I mean, I've learned so much. And I wouldn't have been able to admit this even just two months ago, because I wasn't aware of it. So going silent in her goes to me, which is silence. And also me go see an officer and also me going silent with myself, I'm able to go inward and realize what needs healing. Because should I get back into this relationship? Or should I go into another relationship? I now know what needs attention and what needs work? And what what? What part of my body and mind, body and soul needs more love? **Michael Hingson ** 52:35 Well, and if you really feel you have that deep of a spiritual relationship with her, do you reach back out to her or what happens? And **Lino Martinez ** 52:43 that's a great question. I was reaching out with her. Yeah, I was I the reason why. And the reason why we broke up, she literally told me that she cannot give me the same love that I give her in return. But then I started realizing that she could only be friends. And this was literally a month ago. But when that happened, I felt I felt a few things. And this all in all of this was solved all these answers came again from being alone. And this is why I want listeners listening to this. Whoever is going through a breakup. Don't be afraid to go inward. When you go inward and ask yourself questions, ask yourself a million questions, you will get answers. And as much as it hurts, you're gonna plow through it, and you're gonna have incredible self discovery. So my self discovery, I realized, we're, we're all mirrors of each other. There are things aspects about you, Michael, that I have in common with, there's aspects about anybody that I come in contact with, that I have in common with, we're all mirrors of each other. And so when she felt that she couldn't give me the love, and I'm I can't speak for her because I'm not her, but I feel I can feel and what I felt at the moment as well, when she said that, and and she left I felt at that moment, Well, geez, that must mean that I'm undeserving, and I'm unloving. And then I realized, but wait, she's the one saying that by saying she can't give me the same love that I that I give in return. That message is the same message. She's saying I'm undeserving, I'm unloving, and therefore, I can't give you that much love. But I'm also feeling the same way. And so and I started to reach out to her shortly after the breakup within within a week, and it was text messaging, how are you and she was responsive. And I must have text within the last month, maybe about four or five times when she did respond. However, I finally realized two weeks ago, you know what, it's time for her to reach out to me, because at this point, it's not self love anymore. At this point, when you start filling up someone else's cup and pushing them to communicate, you're taking love away from yourself. And so I needed to go back and fill my own cup and because it was bringing me down, why is it me reaching out? Why am I always the one reaching out? Well, you know what, I also need to give her the benefit of the doubt that she's also growing and that she's learning and that she's going to get stronger and that she does have the ability and the capability to reach out to me and communicate. I'm not going to give her I'm not going to doubt her growth is either and so I'm giving her the opportunity to come to me when she's ready. And because I have no doubt in the love that we've experienced together, we didn't have a toxic relationship. There were simple traumas. And whenever there's trauma versus toxicity, you can work through traumas, you can learn to love each other, and through love, grow and expand and understand where there needs more attention. **Michael Hingson ** 55:19 Yeah. And the reality is, of course, that the love that she gives you is different than the love that you give her anyway, because you're two different beings. And then that's a matter of figuring out how to blend those. And clearly, that's part of what you're hoping that she will work on an hour, or come to realize, and then you'll be able to get back together. **Lino Martinez ** 55:42 Absolutely. Michael, and I'm not going to deny that there's been thoughts recently Oh, it's been two weeks since I reached out should I reach out but there's there's this nagging voice inside me that says allow her, give her she she is strong enough, because in me doing so there's a lot of things that I'm that I'm not allowing, I'm gonna allow a not allowing her to grow. If I come in and keep and keep kind of like intruding into these unspoken energetic boundaries. And in doing that, it's also manipulative in a way even though it's not intended to be that way. It's hang on a minute, I'm feeling bad. I'm feeling sad. Let me get a hold of you. I miss you. Rather than you know, what, how about I trust the situation and trust that we're both growing and that there's still love within our distance? Yeah. **Michael Hingson ** 56:26 And hopefully it works out, you'll you'll figure it out. I have no doubt about that. And the right solution will come along whatever it happens to be. **Lino Martinez ** 56:35 I believe that, Michael, thank you. **Michael Hingson ** 56:37 What other advice might you have for anyone else who may be suffering or feeling challenged in one way or another? **Lino Martinez ** 56:45 It's such a good question. Because so many, I mean, everybody, there's so many so much suffering going on going on in this world. Yeah, **Michael Hingson ** 56:51 don't watch the news. I know. But **Lino Martinez ** 56:57 you know, pay attention to, to your feelings. Because all your feelings are messages. And as negative as it can feel, and is in as daunting as it could be. It can always be turned into something beautiful, even grief, even in the grief of losing someone, there's always beauty in grief. And when you can turn pain and sorrow into beauty. That's where all the magic starts to happen. And don't give up. There's no reason to give up. There's, there's also people need to understand that there's no failure. At all, there's only clarifying things in this world, you can't fail, there's only things that are constantly showing you clarification. And also Success is not final. And also failure is not fatal. So as long as you know that Success is not final, you're going to always be striving for to do something else or feel something else. And that's okay. There's a flexibility of flow of life and ebb and flow. And just like the ocean waves, they come back and they back and forth. We're the same way the same, that same beauty that Earth possess we possess within ourselves. **Michael Hingson ** 58:08 I think it was in the Henry Drummond book that I mentioned one of his lectures, he talked about the fact that teachers can teach a lot of things, but really the only person who can teach you is you. You're your own real teacher, everything else is information or concepts, but you have to teach it to yourself. And that has taught me to learn to realize that, in fact, I am my own best teacher, I have now learned not to say I'm my own worst critic anymore. I always said, I didn't. And I don't journal a lot as such. But whenever I give a speech, I reply to record it. And then I can go back and listen to it and improve. And I've realized that it's not being my own worst critic. It's my faith and my recognition that I'm my own best teacher, I get to listen to it, and hear what happened. And I can go on thinking, could I have done that better? Was it as good as it could be? Or how can I make the best part even better? And that's only something that I can do. No one else can do it. So I am a firm believer and I my own best teacher. **Lino Martinez ** 59:14 I totally agree with you. I love I said that. How can I make the best better? **Michael Hingson ** 59:19 Yeah, I love it. And maybe the answer is it's as good as it can possibly be. But it's okay to ask yourself. Yeah, absolutely. Which is what it's really about. Well, this has been fun. But if people want to reach out to you, and learn more from you, I don't know whether in the things that you do. Do you work virtually or just in person? **Lino Martinez ** 59:43 Do I work virtually **Michael Hingson ** 59:45 doing you've got a doctorate in psychology do you do and do you have any kind of practice or do you coach or teach people? **Lino Martinez ** 59:50 Yeah, actually, I'm a professor in psychology and there you go. This fall I'm teaching. It's called psychodynamic theory. And so I'm not teaching right now in the fall. I mean, I'm sorry, in the summertime, we actually did teach the summer but summer session ended a month ago. So

Die Themen der Wissensmeldungen: +++ Nach dem 2. Weltkrieg konnten frühere Nationalsozialisten im Bundespräsidialamt gut Karriere machen +++ wie sich eine Atlantik-Überquerung im Ruderboot optimieren lässt +++ Forschende haben es geschafft, Hühner gegen Vogelgrippe-Virus resistent zu machen +++ **********Weiterführende Quellen zu dieser Folge:Das Bundespräsidialamt und der Umgang mit der NS-Vergangenheit 1949–1994. 11. Oktober 2023Mental and physiological wellbeing while rowing across the North Atlantic: a single-case study of subjective versus objective data Front. Physiol., 19 September 2023Creating resistance to avian influenza infection through genome editing of the ANP32 gene family. 10 October 2023The growing energy footprint of artificial intelligence. October 10, 2023Violence trends in the ancient Middle East between 12,000 and 400 BCE. 09 October 2023More than 10,000 pre-Columbian earthworks are still hidden throughout Amazonia. 5 Oct 2023**********Ihr könnt uns auch auf diesen Kanälen folgen: Tiktok und Instagram.

References Prostaglandins Leukot Essent Fatty Acids. 2015 Jul;98:49-55 Int J Biol Sci. 2015; 11(11):1272–1280 Front. Physiol., 01 June 2018 Int. J. Mol. Sci. 2019, 20(6), 1505 Front Immunol. 2023; 14: 1149366 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Nerw błędny jest kluczowym elementem autonomicznego układu nerwowego, który unerwia większość narządów, zwłaszcza tych w obrębie przewodu pokarmowego. Nerw błędny jest głównym składnikiem osi neuroendokrynnoimmunologicznej, która zapewnia regulację wrodzonej odpowiedzi odpornościowej przed zakażeniami i stanem zapalnym, pomagając organizmowi przywrócić równowagę. Z tego powodu stymulacja nerwu błędnego jest aktualnie intensywnie badany pod kątem przeciwzapalnego potencjału terapeutycznego w niektórych chorobach. Gość: dr Maciej Duczyński – fizjoterapeuta i student osteopatii. Od lat pasjonuje się układem nerwowym i możliwościami poprawy jego funkcjonowania poprzez terapię manualną. Maciek popularyzuje metodę elektrostymulacji nerwu błędnego w leczeniu pacjentów ze schorzeniami autoimmunologicznymi, zaburzeniami funkcji przewodu pokarmowego i depresją. Misją Maćka jest przede wszystkim edukacja i pokazywanie ludziom, że osiągnięcie zdrowia nie musi być bardzo skomplikowane. Na co dzień pracuje z pacjentami w gabinecie Triada Zdrowia na warszawskich Włochach oraz prowadzi szkolenia dla fizjoterapeutów w firmie Neuroprojekt. Oprócz tego Maćka znajdziecie na instagramie pod nickiem @duczynski.m W odcinku znajdziesz odpowiedzi m. in. na następujące pytania: Na czym polega praca fizjoterapeuty i osteopaty? Czym jest terapia manualna? Dlaczego chorujemy? Jak emocje i stres wpływają nasze ciało? Czym jest zmienność rytmu zatokowego (HRV)? Czym jest nerw błędny i czy ma związek z chorobami? Czym jest teoria poliwagalna? Jak możemy stymulować nerw błędny? Czy elektrostymulacja nerwu błędnego jest metoda leczenia chorób autoimmunologicznych i metabolicznych? Lista publikacji o których wspominamy w podcaście: Bonaz B. i wsp. Anti-inflammatory properties of the vagus nerve: potential therapeutic implications of vagus nerve stimulation. J Physiol. 2016 Oct 15;594(20):5781-5790. Kelly M.J. i wsp. Manipulation of the inflammatory reflex as a therapeutic strategy. Cell Rep Med. 2022 Jul 19;3(7):100696. Kuzior K. i Gorczyca W. Odruch zapalny jako przykład współzależności pomiędzy układem odpornościowym i nerwowym. Chemistry, environment, biotechnology 2010, XIV, 139–151. Bellocchi Ch. i wsp. The Interplay between Autonomic Nervous System and Inflammation across Systemic Autoimmune Diseases. Int J Mol Sci . 2022 Feb 23;23(5):2449. Adlan A.M. i wsp. Autonomic function and rheumatoid arthritis—A systematic review. Semin. Arthritis Rheum. 2014, 44, 283–304. Ghia J.-E. i wsp. Vagus nerve integrity and experimental colitis. Am. J. Physiol. Liver Physiol. 2007, 293,G560–G567. Koopman F.A. i wsp. Vagus nerve stimulation inhibits cytokine production and attenuates disease severity in rheumatoid arthritis. Proc. Natl. Acad. Sci. USA 2016, 113, 8284–8289 Sorski L. i Gidron Y. The Vagal Nerve, Inflammation, and Diabetes-A Holy Triangle. Cells. 2023 Jun 15;12(12):1632. Fang J. i wsp. Transcutaneous Vagus Nerve Stimulation Modulates Default Mode Network in Major Depressive Disorder. Biol Psychiatry . 2016 Feb 15;79(4):266-73. de Moraes T.l. i wsp. Brief periods of transcutaneous auricular vagus nerve stimulation improve autonomic balance and alter circulating monocytes and endothelial cells in patients with metabolic syndrome: a pilot study. Bioelectron Med. 2023 Mar 31;9(1):7. Hilz M.J. Transcutaneous vagus nerve stimulation - A brief introduction and overview. Auton Neurosci. 2022 Dec;243:103038. Inbaraj G. i wsp. Immediate Effects of OM Chanting on Heart Rate Variability Measures Compared Between Experienced and Inexperienced Yoga Practitioners. Int J Yoga. 2022 Jan-Apr;15(1):52-58. Black D.S. i Slavich G.M. Mindfulness meditation and the immune system: a systematic review of randomized controlled trials.Ann N Y Acad Sci. 2016 Jun;1373(1):13-24.

New research shows exercise is one of the most important tools for fighting off respiratory infections, including COVID-19. Here's a summary of the most recent data... Support your Workout Sessions and Healthy Hydration with this Creatine Electrolyte Combo by MYOXCIENCE: http://bit.ly/electrolyte-stix Save 12% with code podcast at checkout Studies, Video and Images: https://bit.ly/3KRY2z2   1. Torres, G., Constantinou, D., Gradidge, P., Patel, D. & Patricios, J. Exercise is the Most Important Medicine for COVID-19. Curr. Sports Med. Rep. 22, 284–289 (2023).   2. Jimeno-Almazán, A. et al. Effects of a concurrent training, respiratory muscle exercise, and self-management recommendations on recovery from post-COVID-19 conditions: the RECOVE trial. J. Appl. Physiol. 134, 95–104 (2023). Time Stamps: 00:00 Exercise is the most important medicine for COVID19. 02:10 Exercise reduces the severity of upper respiratory tract infections. 02:30 Exercise reduces odds of contracting COVID, being hospitalized, being in the ICU, and risk of death. 05:10 Exercise reduces inflammation. 07:30 Autophagy and mitophagy occur with every exercise session, optimizing energy production. 09:20 Exercise prevents the accumulation of exhausted T cells. 10:45 Exercise releases myokines that help the thymus gland release T cells. 11:00 T cells and B cells are mobilized in the blood by increased catecholamines during exercise, and likely cold exposure. 11:20 Natural killer cells and viral specific T cells occur with each exercise session. 12:00 Aerobic exercise mobilizes T lymphocytes, T cells, and effector cells. 13:00 Exercise exerts anti-inflammatory effects within the heart. 13:50 Stem cells from muscle are released during intense exercise. 14:35 Your frontline mucosal defense is impacted by exercise. 15:30 Myokines from exercise increase BDNF.  

Women are not small men.  We know that women are physiologically different to men. But how do they differ? And what does that mean when it comes to training for triathlon, coaching females and providing nutrition support? We're kicking off Part 1 of a new Female Athlete Series on the podcast with the physiological differences between male and female athletes:   Body Fat levels Muscle mass and strength Vo2max Lactate Threshold Thermoregulation Fat Oxidation Hormones As you can see, there are lots of differences that we need to take into consideration.  There is no one size fits all. When we understand female physiology, we can do better and be better. Athletes, coaches and sports dietitians. LINKS Check how well you're doing when it comes to your nutrition with our 50 step checklist to Triathlon Nutrition Mastery: dietitianapproved.com/checklist Start working on your nutrition now with my Triathlon Nutrition Kickstart course: dietitianapproved.com/kickstart It's for you if you're a triathlete and you feel like you've got your training under control and you're ready to layer in your nutrition. It's your warmup on the path to becoming a SUPERCHARGED triathlete – woohoo! Join the waitlist for our next opening of the Triathlon Nutrition Academy www.dietitianapproved.com/academy   Website: www.dietitianapproved.com Instagram: @Dietitian.Approved  @triathlonnutritionacademy Facebook: www.facebook.com/DietitianApproved   References: Carter, S. L., Rennie, C., and Tarnopolsky, M. A. (2001). Substrate utilization during endurance exercise in men and women after endurance training. Am. J. Physiol. Endocrinol. Metabolism. 280, 898–907. Heydenreich, J., Kayser, B., Schutz, Y., and Melzer, K. (2017). Total energy expenditure, energy intake, and body composition in endurance athletes across the training season: a systematic review. Sports Medicine. Open 3:8. doi: 10.1186/ s40798- 017- 0076- 1 Lepers R. Sex Difference in Triathlon Performance. Frontiers Physiology. 2019 Jul 24;10:973. doi: 10.3389/fphys.2019.00973. PMID: 31396109; PMCID: PMC6668549.Lepers, R. (2008). Analysis of Hawaii ironman performances in elite triathletes from 1981 to 2007. Med. Sci. Sports Exerc. 40, 1828–1834. doi: 10.1249/MSS. 0b013e31817e91a4 Marino, F. E., Mbambo, Z., Kortekaas, E., Wilson, G., Lambert, M. I., Noakes, T. D., et al. (2000). Advantages of smaller body mass during distance running in warm, humid environments. Pflugers. Arch. 441, 359–367. doi: 10.1007/ s004240000432 Millet, G. P., and Bentley, D. J. (2004). The physiological responses to running after cycling in elite junior and senior triathletes. Int. J. Sports Med. 25, 191–197. doi: 10.1055/s-2003-45259 Rüst, C. A., Knechtle, B., Rosemann, T., and Lepers, R. (2012b). Sex difference in race performance and age of peak performance in the ironman triathlon world championship from 1983 to 2012. Extrem. Physiol. Med. 14:15. doi: 10.1186/ 2046- 7648- 1- 15 The Triathlon Nutrition Academy is a podcast by Dietitian Approved. All rights reserved. www.dietitianapproved.com/academy Dietitian Approved acknowledges the Traditional custodians of the Land we have recorded this podcast on, The Turrbal and Jagera peoples. We pay our respects to their elders past and present and extend that respect to all Aboriginal and Torres Strait Islander cultures.See omnystudio.com/listener for privacy information.

Biologics and the Peripheral Nerve.   Claim CME The CE experience for this Podcast is powered by CMEfy - click here to reflect and earn credits: https://earnc.me/TgB18M   Dr. Rosenblum discuss his upcoming talk at the Appalachian Region Spine and Pain Meeting:  Incorporating Ultrasound into a Spine and Pain Practice on April 14-16 2023 and the topics he plans to include: Ultrasound Guided Knee therapies, cluneal nerve, caudal, brachial plexus and more!   Today's podcast (inspired by TOBI and Dr. Sudhir Diwan, Dr. Sheldon Jordon and Dr. Rikin Patel's ASIPP Lectures)  focuses on the risk and benefits of performing PRP injection onto a nerve.  Dr. Rosenblum discusses:    Possible fibrosis of the ulna nerve after using PRP for partial ulnar collateral ligament tears  Best Time for PRP Injection after Nerve Regeneration  Alpha 2-macroglobulin (what is it?)  PRP for moderate to severe carpal tunnel syndrome   Featured Courses!   May 25, 2023 Private Pain Group   Ultrasound Course- NYC (Sold out) Ultrasound Guided Regional Anesthesia and Pain Medicine NYC- April 22, 2023 Regenerative Pain Medicine Course NYC- May 13 Pain Management Board Review/Refresher Course/ Ultrasound Training NYC- June 9-11, 2023 see the full schedule for our July and August US IPM Courses!   References Robert G. Thompson, Kendall Bradley, Gary M. Lourie, Ulnar nerve dysfunction at the elbow after platelet-rich plasma treatment for partial ulnar collateral ligament injuries,JSES Reviews, Reports, and Techniques,Volume 1, Issue 1,2021,Pages 41-44,ISSN 2666-6391,   Si-Ru Chen, Yu-Ping Shen, Tsung-Yen Ho, Tsung-Ying Li, Yu-Chi Su, Yu-Ching Chou, Liang-Cheng Chen, Yung-Tsan Wu,One-Year Efficacy of Platelet-Rich Plasma for Moderate-to-Severe Carpal Tunnel Syndrome: A Prospective, Randomized, Double-Blind, Controlled Trial,Archives of Physical Medicine and RehabilitationVolume 102, Issue 5,2021, Pages 951-958,ISSN 0003-9993,https://doi.org/10.1016/j.apmr.2020.12.025.   Rehman, A.A., Ahsan, H. and Khan, F.H. (2013), Alpha-2-macroglobulin: A physiological guardian. J. Cell. Physiol., 228: 1665-1675. https://doi.org/10.1002/jcp.24266   Muhammad Pandunugrahadi, Komang Agung Irianto, Oen Sindrawati, "The Optimal Timing of Platelet-Rich Plasma (PRP) Injection for Nerve Lesion Recovery: A Preliminary Study", International Journal of Biomaterials, vol. 2022, Article ID 9601547, 7 pages, 2022. https://doi.org/10.1155/2022/9601547

Biologics and the Peripheral Nerve.   Claim CME The CE experience for this Podcast is powered by CMEfy - click here to reflect and earn credits: https://earnc.me/TgB18M   Dr. Rosenblum discuss his upcoming talk at the Appalachian Region Spine and Pain Meeting:  Incorporating Ultrasound into a Spine and Pain Practice on April 14-16 2023 and the topics he plans to include: Ultrasound Guided Knee therapies, cluneal nerve, caudal, brachial plexus and more!   Today's podcast focuses on the risk and benefits of performing PRP injection onto a nerve.  Dr. Rosenblum discusses:    Possible fibrosis of the ulna nerve after using PRP for partial ulnar collateral ligament tears  Best Time for PRP Injection after Nerve Regeneration  Alpha 2-macroglobulin (what is it?)  PRP for moderate to severe carpal tunnel syndrome   Featured Courses!   May 25, 2023 Private Pain Group   Ultrasound Course- NYC (Sold out)   Ultrasound Guided Regional Anesthesia and Pain Medicine NYC- April 22, 2023 Regenerative Pain Medicine Course NYC- May 13 Pain Management Board Review/Refresher Course/ Ultrasound Training NYC- June 9-11, 2023 see the full schedule for our July and August US IPM Courses!   References Robert G. Thompson, Kendall Bradley, Gary M. Lourie, Ulnar nerve dysfunction at the elbow after platelet-rich plasma treatment for partial ulnar collateral ligament injuries,JSES Reviews, Reports, and Techniques,Volume 1, Issue 1,2021,Pages 41-44,ISSN 2666-6391,   Si-Ru Chen, Yu-Ping Shen, Tsung-Yen Ho, Tsung-Ying Li, Yu-Chi Su, Yu-Ching Chou, Liang-Cheng Chen, Yung-Tsan Wu,One-Year Efficacy of Platelet-Rich Plasma for Moderate-to-Severe Carpal Tunnel Syndrome: A Prospective, Randomized, Double-Blind, Controlled Trial,Archives of Physical Medicine and RehabilitationVolume 102, Issue 5,2021, Pages 951-958,ISSN 0003-9993,https://doi.org/10.1016/j.apmr.2020.12.025.   Rehman, A.A., Ahsan, H. and Khan, F.H. (2013), Alpha-2-macroglobulin: A physiological guardian. J. Cell. Physiol., 228: 1665-1675. https://doi.org/10.1002/jcp.24266   Muhammad Pandunugrahadi, Komang Agung Irianto, Oen Sindrawati, "The Optimal Timing of Platelet-Rich Plasma (PRP) Injection for Nerve Lesion Recovery: A Preliminary Study", International Journal of Biomaterials, vol. 2022, Article ID 9601547, 7 pages, 2022. https://doi.org/10.1155/2022/9601547

Biologics and the Peripheral Nerve.   Claim CME The CE experience for this Podcast is powered by CMEfy - click here to reflect and earn credits: https://earnc.me/TgB18M   Dr. Rosenblum discuss his upcoming talk at the Appalachian Region Spine and Pain Meeting:  Incorporating Ultrasound into a Spine and Pain Practice on April 14-16 2023 and the topics he plans to include: Ultrasound Guided Knee therapies, cluneal nerve, caudal, brachial plexus and more!   Today's podcast (inspired by TOBI and Dr. Sudhir Diwan, Dr. Sheldon Jordon and Dr. Rikin Patel's ASIPP Lectures)  focuses on the risk and benefits of performing PRP injection onto a nerve.  Dr. Rosenblum discusses:    Possible fibrosis of the ulna nerve after using PRP for partial ulnar collateral ligament tears  Best Time for PRP Injection after Nerve Regeneration  Alpha 2-macroglobulin (what is it?)  PRP for moderate to severe carpal tunnel syndrome   Featured Courses!   May 25, 2023 Private Pain Group   Ultrasound Course- NYC (Sold out) Ultrasound Guided Regional Anesthesia and Pain Medicine NYC- April 22, 2023 Regenerative Pain Medicine Course NYC- May 13 Pain Management Board Review/Refresher Course/ Ultrasound Training NYC- June 9-11, 2023 see the full schedule for our July and August US IPM Courses!   References Robert G. Thompson, Kendall Bradley, Gary M. Lourie, Ulnar nerve dysfunction at the elbow after platelet-rich plasma treatment for partial ulnar collateral ligament injuries,JSES Reviews, Reports, and Techniques,Volume 1, Issue 1,2021,Pages 41-44,ISSN 2666-6391,   Si-Ru Chen, Yu-Ping Shen, Tsung-Yen Ho, Tsung-Ying Li, Yu-Chi Su, Yu-Ching Chou, Liang-Cheng Chen, Yung-Tsan Wu,One-Year Efficacy of Platelet-Rich Plasma for Moderate-to-Severe Carpal Tunnel Syndrome: A Prospective, Randomized, Double-Blind, Controlled Trial,Archives of Physical Medicine and RehabilitationVolume 102, Issue 5,2021, Pages 951-958,ISSN 0003-9993,https://doi.org/10.1016/j.apmr.2020.12.025.   Rehman, A.A., Ahsan, H. and Khan, F.H. (2013), Alpha-2-macroglobulin: A physiological guardian. J. Cell. Physiol., 228: 1665-1675. https://doi.org/10.1002/jcp.24266   Muhammad Pandunugrahadi, Komang Agung Irianto, Oen Sindrawati, "The Optimal Timing of Platelet-Rich Plasma (PRP) Injection for Nerve Lesion Recovery: A Preliminary Study", International Journal of Biomaterials, vol. 2022, Article ID 9601547, 7 pages, 2022. https://doi.org/10.1155/2022/9601547

In this episode, Jess hosts Lynndsey on a very quick discussion on strategies that can help alleviate or at least help with muscle soreness. They go over easing into training as well as post-exercise active recovery, compression clothing, heat/cold exposure, massage, foam rolling, and Lynndsey's personal habits to stay fresh for her training!  References: Armstrong R. B. (1984). Mechanisms of exercise-induced delayed onset muscular soreness: a brief review. Med. Sci. Sports Exerc. 16, 529–538. 10.1249/00005768-198412000-00002 Beliard S., Chauveau M., Moscatiello T., Cros F., Ecarnot F., Becker F. (2015). Compression garments and exercise: no influence of pressure applied. J. Sports Sci. Med. 14, 75–83.  Bieuzen F., Brisswalter J., Easthope C., Vercruyssen F., Bernard T., Hausswirth C. (2014b). Effect of wearing compression stockings on recovery after mild exercise-induced muscle damage. Int. J. Sports Physiol. Perform. 9, 256–264. 10.1123/ijspp.2013-0126 Brown F., Gissane C., Howatson G., van Someren K., Pedlar C., Hill J. (2017). Compression garments and recovery from exercise: a meta-analysis. Sports Med. 47, 2245–2267. 10.1007/s40279-017-0728-9  Crane, Justin D., Daniel I. Ogborn, Colleen Cupido, Simon Melov, Alan Hubbard, Jacqueline M. Bourgeois, and Mark A. Tarnopolsky. “Massage Therapy Attenuates Inflammatory Signaling After Exercise-Induced Muscle Damage.” Science Translational Medicine 4, no. 119 (February 1, 2012): 119ra13-119ra13. doi:10.1126/scitranslmed.3002882. Dupuy, O., Douzi, W., Theurot, D., Bosquet, L., & Dugué, B. (2018). An evidence-based approach for choosing post-exercise recovery techniques to reduce markers of muscle damage, soreness, fatigue, and inflammation: A systematic review with meta-analysis. Frontiers in Physiology, 9. https://doi.org/10.3389/fphys.2018.00403 Fröhlich M., Faude O., Klein M., Pieter A., Emrich E., Meyer T. (2014). Strength training adaptations after cold-water immersion. J. Strength Cond. Res. 28, 2628–2633. 10.1519/JSC.0000000000000434  Guo J., Li L., Gong Y., Zhu R., Xu J., Zou J., et al.. (2017). Massage alleviates delayed onset muscle soreness after strenuous exercise: a systematic review and meta-analysis. Front Physiol. 8:747. 10.3389/fphys.2017.00747 Herbert R. D., de Noronha M., Kamper S. J. (2011). Stretching to prevent or reduce muscle soreness after exercise. Cochrane Database Syst Rev. CD004577. 10.1002/14651858.CD004577.pub3 Hill J., Howatson G., van Someren K., Leeder J., Pedlar C. (2014). Compression garments and recovery from exercise-induced muscle damage: a meta-analysis. Br. J. Sports Med. 48, 1340–1346. 10.1136/bjsports-2013-092456 Kargarfard M., Lam E. T., Shariat A., Shaw I., Shaw B. S., Tamrin S. B. (2016). Efficacy of massage on muscle soreness, perceived recovery, physiological restoration and physical performance in male bodybuilders. J. Sports Sci. 34, 959–965. 10.1080/02640414.2015.1081264 Nahon, R. L., Silva Lopes, J. S., & Monteiro de Magalhães Neto, A. (2021). Physical therapy interventions for the treatment of delayed onset muscle soreness (DOMS): Systematic review and meta-analysis. Physical Therapy in Sport: Official Journal of the Association of Chartered Physiotherapists in Sports Medicine, 52, 1–12. https://doi.org/10.1016/j.ptsp.2021.07.005 Schoenfeld, B. J., & Contreras, B. (2013). Is postexercise muscle soreness a valid indicator of muscular adaptations? Strength and Conditioning Journal, 35(5), 16–21. https://doi.org/10.1519/ssc.0b013e3182a61820 Strategies for reducing delayed-onset muscle soreness. (n.d.). Human Kinetics. Retrieved January 26, 2023, from https://us.humankinetics.com/blogs/excerpt/strategies-for-reducing-delayed-onset-muscle-soreness Suzuki M., Umeda T., Nakaji S., Shimoyama T., Mashiko T., Sugawara K. (2004). Effect of incorporating low intensity exercise into the recovery period after a rugby match. Br. J. Sports Med. 38, 436–440. 10.1136/bjsm.2002.004309 Zainuddin, Zainal, Mike Newton, Paul Sacco, and Kazunori Nosaka. “Effects of Massage on Delayed-Onset Muscle Soreness, Swelling, and Recovery of Muscle Function.” Journal of Athletic Training 40, no. 3 (September 2005): 174–80. Zainuddin Z., Sacco P., Newton M., Nosaka K. (2006). Light concentric exercise has a temporarily analgesic effect on delayed-onset muscle soreness, but no effect on recovery from eccentric exercise. Appl. Physiol. Nutr. Metab. 31, 126–134. 10.1139/h05-010

Front. Physiol., 13 January 2023Sec. Exercise PhysiologyVolume 13 - 2022 | https://doi.org/10.3389/fphys.2022.10...The Sports Science Dudes represents the opinions of the hosts and guests and are not the official opinions of the International Society of Sports Nutrition (ISSN), the Society for NeuroSports, or Nova Southeastern University. The advice provided on this show should not be construed as medical advice and is purely an educational forum.About the ShowHosted by Jose Antonio PhD - The CEO of the ISSN, www.issn.net https://www.sportsnutritionsociety.or... Twitter: @JoseAntonioPhD Co-host Anthony Ricci EdDAnthony Ricci | College of Health Care Sciences | NSU (nova.edu)Twitter: @sportsci_psyDoc

ReviewersRyan Thomas, MDElizabeth Fiorino, MDRob Tepper, MDAlbin Leong, MDAdditional AcknowledgementsMichael Kiernan, MD (for expertise on scuba physiology)Contact InformationEmail: TidalVolumeATSPeds@gmail.comTwitter: @ATSPedsReferences Ratjen FA, Colin AA, Stark AR, Mead J, And Wohl MEB, Changes of time constants during infancy and early childhood. J. Appl. Physiol. 67(5):2112-2115, 1989. LeSouef PN, England SJ, and Bryan AC, Passive Respiratory Mechanics in Newborns and Children, Am Rev Respir Dis, 1984:  129:552-558. Otis AB et al, Mechanical Factors in the Distribution of Ventilation, J Appl Physiol,  8(4):  427-443. Deranged Physiology > Respiratory System > Mechanics of Breathing >Time Constants:  https://derangedphysiology.com/main/cicm-primary-exam/required-reading/respiratory-system/Chapter%20034/time-constants

Fonte: Santana, M. R. D., Pontes, Y. M. D. M., Benjamim, C. J. R., Rodrigues, G. D. S., Liberalino, G. A., Mangueira, L. B., ... & Valenti, V. E. (2022). A Single Dose of Beer after Moderate Aerobic Exercise Did Not Affect the Cardiorespiratory and Autonomic Recovery in Young Men and Women: A Crossover, Randomized and Controlled Trial. International Journal of Environmental Research and Public Health, 19(20), 13330. Wiklund, U.; Karlsson, M.; Oström, M.; Messner, T. Influence of energy drinks and alcohol on post-exercise heart rate recovery and heart rate variability. Clin. Physiol. Funct. Imaging 2009, 29, 74–80. - Siga no Instagram: @fabiodominski https://www.instagram.com/fabiodominski/ Gostou do podcast? Você vai gostar mais ainda desse livro! - Livro Exercício Físico e Ciência: Fatos e mitos de Fábio Dominski https://www.amazon.com.br/dp/6586363187?ref=myi_title_dp - Grupo Exercício Físico e Ciência no Telegram: https://t.me/+VazaFBxgPq0y5v8p - Inscreva-se no canal no YouTube: https://www.youtube.com/channel/UC4Dwwly0tJa49CfHC0MSQ7A --- Support this podcast: https://anchor.fm/fabiodominski/support

Not medical licensed advice . Always consult with your doctor:New Treatments For ObesityBMI: 25-30 : overweight  >30 ObeseWHO 2016 40% are over weight and 13% obese slightly higher in females . This is triple that in 1975UK 2019 House of Commons Library  40% are overweight and 30% obese higher in middle aged and elderly menNHS 2021: Children Obesity has gone up in 12 years from 19% to 25% The Surprising Link Between Chronic Inflammation & Obesity—Plus What You Can Do About ItMay 5th 2021Leptins are hormones produced by adipocytes that communicate with the hypothalamus to reduce eating. If you have too much leptin you become leptin resistant and do not stop eating. High leptin levels are also associated with  chronic inflammation.Conversely losing weight reduces systemic inflammation. REVIEW articleFront. Physiol., 29 January 2020Sec. Clinical and Translational PhysiologyChronic Adipose Tissue Inflammation Linking Obesity to Insulin Resistance and Type 2 DiabetesFrederika ZatteralThe key mediator of inflammation in obesity is the innate immune system cell the macrophage that can account for up to 40% of adipose tissue and it differentiates into a pro-inflammatory M1 macrophage setting up chronic inflammation.Obesity and Inflammation: A Vicious CycleDoes obesity cause inflammation or does inflammation lead to obesity?Jun 25, 2020Jennifer LutzObesity causes chronic inflammation via a chronic immune reaction initiated in the adipose tissue but inflammatory cells can go round the body. In addition gut inflammation may be a result also of the poor diet that led to the obesity.We know that obesity has tripled in the last 50 years such that 40% of the western world are obese. In fact 75% are prediabetic.Cardiovascular disease leading to cardiac disease and strokes, diabetes, cancer, depression, osteoarthritis all feed back and make it more likely you will continue to be obese.Higher adiposity and mental health: causal inference using Mendelian randomization Francesco Casanova,Jessica O'Loughlin,Susan Martin,Robin N Beaumont,Andrew R Wood,Edward R Watkins,Rachel M Freathy,Saskia P Hagenaars,Timothy M Frayling,Hanieh Yaghootkar... Show moreAuthor NotesHuman Molecular Genetics, Volume 30, Issue 24, 15 December 2021, Pages 2371–2382, There is a bidirectional relationship between depression and obesity.Genetic sorting showed that it is obesity per se and not the metabolic unhealthiness due to the obesity such as diabetes that leads to depression.That said diabetes from obesity causes depression although obesity itself causes systemic inflammation which is an independent risk factor for depression and cancer.There are also huge psychosocial effects of obesity on mood.Once-Weekly Semaglutide in Adults with Overweight or ObesityNew England Journal Of Medicine March 2021John P.H. Wilding,Once a week subcutaneous Semaglutide reduced weight by up to 20%Semaglutide is a GLP-1 agonist so suppresses Glucagon and increases insulin hence controlling blood sugar. It also slows gastric emptying  increasing satiety and acts on Receptors in the Arcuate Nucleus in the brain to increase satiety.It is already licensed to treat Type 2 diabetes.It also reduces the risk of cardiovascular complication in Type 2 diabetes and at a cellular level reverses atherogenesis. There is a question on worsening the risk of retinopathy.Other GLP-1 agonists : Liraglutide Setmelanotide.CpdFDA Approved Medication for treating ObesityPhentermine, diethylpropion,benzphetamine, phendimetrazine , Orlistat, Phentermine/topiramate Qsymia, Bupropion/naltrexone, Semaglitide, Liraglutide, setmelanotideCpd Phentermine-topiramate: First combination drug for obesityInt J Applied Med Res 2015Singh et alPhentermine is a centrally acting sympathomimetic that reduces appetite and topiramate enhances GABA ergic transmission reducing Dopamine Response to food.This combination causes up to 10% weight loss maintained in 50% for 2 years.The relationship between early weight loss and weight loss maintenance with naltrexone bupropion therapy.THe Lancet Discovery Science 2022Le Roux et alNaltrexone blocks opiate receptors and bupropion (wellbutrin/zyban) blocks reuptake of dopamine  -reward pathways- .and noradrenaline . Weight loss is maintained at 1 yearBoth medications enhance each other on feeding and satiety

In this MEGAphone episode we will be shouting out one of the most informative people to follow on social media that I know about, he specializes in power lifting and biomechanics and injury prevention and physical therapy. His Instagram handle is @SquatUniversity and his name is Dr. Aaron Horschig. As a physical therapist & strength coach, Aaron helps athletes move better, decrease their aches & pains associated with training, and find their true athletic potential.Dr. Horschig wrote an extremely informative and also controversial article that I love and want to share. This information addresses a well known injury protocol… A protocol that I used when I was an athlete in high school in college. A protocol that I used with clients and family members of mine when they got injured… A protocol that I believed in whole heartedly and taught every chance I could. A protocol my college courses taught me, straight out of the text books. It was simple… when you get hurt… the solution is RICE. Rest, Ice, Compression, Elevation. We all knew RICE.   And it turns out… we were all wrong. References: Dr. Aaron Horschig IG: @SquatUniversitywww.squatuniversity.com Book: Rebuilding MiloArticle Citations:1.    Mirkin G, Hoffman M. The Sports Medicine Book. 1978. Little Brown & Co2.    Lu H, Huang D, Saederup N, et al. Macrophages recruited via CCR2 produce insulin-like growth factor-1 to repair acute skeletal muscle injury. FASEB J. 2011;25(1):358-69.3.    Summan M, Warren GL, Mercer RR, Chapman R, et al. Macrophages and skeletal muscle regeneration: a clodronate-containing liposome depletion study. Am J Physiol Regul Integr Comp Physiol. 2006;290(6):R1488-954.    Pelosi L, Giacinti C, Nardis C, Borsellino G, et al. (2007) Local expression of IGF-1 accelerates muscle regeneration by rapidly modulating inflammatory cytokines and chemokines. FASEB J. 21, 1393–14025.    Singh DP, Lonbani ZB, Woodruff MA, Parker JP, et al. Effects of topical icing on inflammation, angiogenesis, revascularization, and myofiber regeneration in skeletal muscle following contusion injury. Front Physiol. 2017;8:93.6.    Takagi R., Fujita N., Arakawa T., Kawada S., Ishii N., Miki A. (2011). Influence of icing on muscle regeneration after crush injury to skeletal muscles in rats. J. Appl. Physiol. 110, 382–388.7.    Tiidus PM. Alternative traetments for muscle injury: massage, cryotherapy, and hyperbaric oxygen. Current reviews in musculoskeletal medicine. 2015;8(2):162-78.    Reinl G. Iced! The illusionary treatment option. 2nd Edition. Gary Reinl. 2014.9.    Khoshnevis S, Kraik NK, Diller KR. Cold-induced vasoconstriction may persist long after cooling ends: an evaluation of multiple cryotherapy units. Knee Surg Sports Traumatol Arthrosc. 2015;23(9):2475-238310. Dirks ML, Wall BT, van Loon L CJ. Interventional strategies to combat muscle disuse atrophy in humans: focus on neuromuscular electoral stimulation and dietary protein. J Appl Physiol. 2018;125:850-86111. Raynor MC, Pietrobon R, Guller U, Higgins LD. Cryotherapy after ACL reconstruction: a meta-analysis. J Knee Surg. 2005;18(2):123-912. Spencer JD, Hayes KC, Alexander IJ. Knee joint effusion and quadriceps reflex inhibition in man. Arch Phys Rehabil. 1984;65:171-17713. Buckwalter JA, Grodzinsky AJ. Loading of healing bone, fibrous tissue, and muscle: implications for orthopaedic practice. J Am Acad Orthop Surg. 1999;7(5):291-9.14. Silveria EM, Rodrigues MF, Krause MS, et al. Acute exercise stimulates macrophage function: possible role of NF-kappaB pathways. Cell Biochem Funct. 2007;25(1):63-7315. Teixeira E, Duarte JA. Skeletal muscle loading changes its regenerative capacity. Sports Med.

Fancy pancy measurements might LOOK GOOD, but a simple TAPE MEASURE around YOUR BELLY might give you the best idea whether you are OVERFAT or not.Dr Phil Maffetone wants you to consider that a FOCUS on WEIGHT means you are missing what matters when it comes to body composition. Think about it. Doesn't your muscle weigh more than fat? But we need to know how much fat we're accumulating because a whole collection of risk factors for most lifestyle diseases make up the MAJORITY of deaths nowadays!In the 26th episode of the Training Science Podcast, Paul and Phil discuss not just the origin of their own professional collaboration, but also many health AND performance related topics around the benefits of basic endurance training for all activities and sports, the large potential of eating whole and real foods, as well as why suddenly we are seeing more extremely fit people suddenly die from heart issues.So you say to yourself “OK, I GET IT! I need healthier ATHLETES. What do I exactly do!?”.We got ya covered with Phil's ATHLETE HEALTH COURSE:https://hiit-science.thinkific.com/courses/athlete-health-high-intensity-interval-training_____________________ Today's speakers:Prof. Paul Laursen https://www.paullaursen.com/ Dr. Phil Maffetone https://philmaffetone.com/  & https://maffetonemusic.com/  _____________________ References:Hetlelid KJ, Plews DJ, Herold E, et alRethinking the role of fat oxidation: substrate utilisation during high-intensity interval training in well-trained and recreationally trained runners. BMJ Open Sport & Exercise Medicine 2015;1:e000047. doi: 10.1136/bmjsem-2015-000047Maffetone, P.B., Laursen, P.B. Athletes: Fit but Unhealthy?. Sports Med - Open 2, 24 (2016). https://doi.org/10.1186/s40798-016-0048-xMaffetone P and Laursen PB (2020) Maximum Aerobic Function: Clinical Relevance, Physiological Underpinnings, and Practical Application. Front. Physiol. 11:296. doi: 10.3389/fphys.2020.00296Maffetone PB and Laursen PB (2020) The Perfect Storm: Coronavirus (Covid-19) Pandemic Meets Overfat Pandemic. Front. Public Health 8:135. doi: 10.3389/fpubh.2020.00135Maffetone PB and Laursen PB (2022) COVID-Related Athletic Deaths: Another Perfect Storm? Front. Sports Act. Living 4:829093. doi: 10.3389/fspor.2022.829093_____________________ 

References Dr Guerra's notes Front. Physiol., 30 January 2019 | https://doi.org/10.3389/fphys.2019.00042 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message Support this podcast: https://anchor.fm/dr-daniel-j-guerra/support

References Dr. Guerra's lecture notes Front. Physiol., 30 January 2019 | https://doi.org/10.3389/fphys.2019.00042 Cold Spring Harb PerspectBiol. 2018 Feb; 10(2): a028415. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message Support this podcast: https://anchor.fm/dr-daniel-j-guerra/support

HIFT representa un método apropiado para mejorar el rendimiento cognitivo, específicamente la memoria de trabajo. Autor Jan Wilke Department of Sports Medicine, Goethe University Frankfurt am Main, Ginnheimer Landstraße 39, 60487, Frankfurt am Main, Germany. wilke@sport.uni-frankfurt.de. Enlace al Articulo Original en Ingles Los ejercicios aeróbicos y de resistencia (con pesas) aumentan de manera inmediata el rendimiento cognitivo (PC). El entrenamiento funcional de alta intensidad (HIFT) combina las características de ambos regímenes, pero su efecto sobre el rendimiento cognitivo no está claro. Treinta y cinco individuos sanos (26,7 ± 3,6 años, 18 mujeres) fueron asignados al azar a tres grupos. El primer grupo (HIFT) realizó un entrenamiento funcional con el máximo esfuerzo y en formato de circuito involucrando todos los grupos musculares del cuerpo, mientras que el segundo grupo (WALK) caminó al 60% de la reserva de frecuencia cardíaca. El tercer grupo permaneció físicamente inactivo leyendo un libro (CON). Antes y después del período de intervención que duro 15 minutos, el rendimiento cognitivo se evaluó con el Stroop Task, Trail Making Test y Digit Span Test. Se utilizaron ANOVA de medidas repetidas e intervalos de confianza del 95% post-hoc para detectar diferencias en los grupos y tiempo (previo y posterior a los protocolos). Se encontró una interacción significativa entre los grupos y el tiempo para la condición de conteo hacia atras de Digit Span Test (p = 0.04, IC 95%). HIFT fue superior a WALK y CON. Ademas, el análisis de la puntuación total del Digit Span Test y la condición incongruente del Stroop Task, reveló efectos pre y post (p 0.05). En conclusión, HIFT representa un método apropiado para mejorar de manera inmediata la memoria de trabajo, siendo potencialmente superior al ejercicio de tipo aeróbico moderado. El entrenamiento funcional de alta intensidad (HIFT, por sus siglas en inglés) como metodo de entrenamiento es una tendencia muy popular en el mundo del fitness, que integra el esfuerzo cardiovascular y muscular. El HIFT utiliza movimientos funcionales, multimodales y multiarticulares, por ejemplo, sentadillas, flexiones y burpees (Buckley et al., 2015). Los ejercicios funcionales utilizan todo el cuerpo y provocan un patrón de reclutamiento motor universal (Heinrich et al., 2014). El HIFT también tiene una configuración de intervalos de descanso mínimo o casi nulo (Feito, Heinrich, Butcher, & Poston, 2018). Las características mencionadas anteriormente confieren al HIFT la capacidad de mejorar la fuerza y la potencia muscular, así como de generar adaptaciones cardiovasculares anaeróbicas y aeróbicas, por lo que se ha demostrado que el HIFT desencadena efectos beneficiosos sobre el consumo de oxígeno (Vo2max), la potencia anaeróbica y fuerza muscular (Alcaraz et al., 2008; Brisebois et al., 2018; Menz et al., 2019). Además, el HIFT parece causar también beneficios neurofisiologicos. Los primeros estudios neurocientíficos asocian el HIFT con una reducción aguda del BDNF (García-Suárez et al., 2020), y curiosamente, en intervenciones más largas con un incremento del BDNF basal (Murawska-Ciałowicz et al., 2021). Además, una sesión aguda de entrenamiento del circuito HIFT mejoró la memoria a corto plazo y el control inhibitorio (Wilke et al., 2020) y una intervención de tres meses mejoró el rendimiento en el aprendizaje espacial, la separación de patrones y la capacidad de atención (Ben-Zeev, Hirsh, Weiss, Gornstein y Okun, 2020). En este estudio la intervencion consistía en una sesion de 15 ejercicios funcionales para todo el cuerpo, realizados en formato de circuito con repeticiones de 20 segundos de entrenamiento y 10 segundos de descanso. Con una duración total de 15 minutos. La selección de los ejercicios se basó en dos objetivos principales (a) la implicación de los principales grupos musculares para aumentar el consumo absoluto de oxígeno y (b) la simulación de patrones de movimiento fundamentales de uso diario (por ejemplo, sentadillas, desplantes, flexiones). El rendimiento cognitivo (CP), que puede subdividirse en funciones cognitivas de orden superior (por ejemplo, control inhibitorio o memoria de trabajo) y de orden inferior (por ejemplo, atención o tiempo de reacción). Las revisiones sistemáticas disponibles han investigado los efectos del ejercicio de tipo aeróbico, han detectando un efecto positivo en el CP incluso cuando se realiza como un único entrenamiento. Tanto el ejercicio continuo aerobico de intensidad moderada como de alta intensidad han reportado un impacto positivo en el rendimiento cognitivo. El test de Stroop consta de tres partes. En la primera y segunda sección de captación de la atención, se pide a los participantes que nombren lo más rápidamente posible las palabras escritas o los colores que aparecen en una hoja. La tercera sección representa una medida de control de la inhibición. Las palabras de colores se presentan de forma incongruente (por ejemplo, "verde" escrito en rojo o "azul escrito en amarillo"). Aquí, los participantes deben nombrar el color de la palabra mientras ignoraban las letras. Para el análisis posterior, se registra el tiempo necesario para completar la tarea. Se ha demostrado que el test de Stroop presenta una alta fiabilidad (ICC: 0,82) y consistencia interna (alfa de Cronbach: 0,93-0,97). Es el Episodio 4 Correr y Salud Mental puedes aprender mas sobre esta prueba cognitiva. El test de creación de rastros (TMT) consta de dos partes. En la parte A, los participantes deben conectar números linealmente crecientes utilizando un bolígrafo a la máxima velocidad posible. En la parte B, deben enlazar números y letras sucesivos (por ejemplo, del 1 al a y del 2 al b) de forma alterna. Al igual que en la prueba Stroop, se registra el tiempo necesario para completar la prueba. Los resultados de la prueba proporcionan una medida de detección visual/atención (TMT-A) y de flexibilidad cognitiva/memoria de trabajo (TMT-B). Se ha demostrado una alta fiabilidad (ICC: 0,81-0,86) y validez de constructo de la TMT. En la prueba de amplitud de dígitos, se realizan dos condiciones. En la primera, los participantes tienen que memorizar y repetir cantidades crecientes de números que se les leen. Al principio, deben recordar cuatro números. Si la memorización es satisfactoria, se les leen cinco números los memorizan y repiten, y asi continua subiendo la cantidad de numeros leidos que tienen que memorizar y repetir. Para cada paso, se realizan dos repeticiones y se otorgan uno o cero puntos en función del éxito de la memorización. La prueba termina si se fallan los dos ensayos. La segunda condición es idéntica a la primera, pero los números deben repetirse en orden inverso (por ejemplo, 2, 4, 7, 9 se convierte en 9, 7, 4, 2). Ambas partes de la prueba y la puntuación compuesta están relacionadas con la memoria a corto plazo y la memoria de trabajo. La prueba de amplitud de dígitos es fiable en las mediciones repetidas (r = 0,73). Los participantes del grupo WALK realizaron 15 minutos de marcha en cinta rodante al 60% de la reserva de frecuencia cardíaca individual. La RFC se determina mediante la fórmula de Karvonen (frecuencia cardíaca en reposo + ((frecuencia cardíaca máxima - frecuencia cardíaca en reposo) x intensidad). Esto es porque Los resultados de este estudio sugieren que el HIFT puede mejorar de forma inmediata el rendimiento cognitivo, concretamente la memoria a corto plazo/de trabajo y el control inhibitorio. Siendo el HIFT ligeramente superior al ejercicio aerobico continuo. Los autores mencionan que los posibles mecanismos que explican este aumento en el rendimiento cognitivo son Aumento de la perfusión cerebral tras el ejercicio de resistencia (Querido & Sheel, 2007; Ogoh & Ainslie, 2009). El aumento de los niveles séricos de cortisol y BDNF, que se ha reportado con entrenamiento de resistencia (pesas) (Tsai, et al. 2014; Yarrow, et al. 2010). Sin embargo los resultados son contradictorios en el sentido que no reportan mejoras con el ejercicio aeróbico, las cuales han sido encontradas en estudios anteriores con intensidades del 40 al 80% de la capacidad maxima de oxigeno ( Brisswalter, et al. 2002; Chang, et al. 2012). Acerca de este tema, Browne et al. 2017 sugiere que multiples factores, como el nivel de forma física y el modo de ejercicio, influyen en la relación entre el ejercicio y la cognición. Una implicación clinica práctica importante del presente estudio es que el HIFT representa una alternativa al uso de otros métodos de entrenamiento convencionales, no sólo en lo que respecta a la mejora o recuperacion de la función muscular y cardiovascular (Wilke, et al. 2020; Menz, et al. 2019), sino también cuando se pretende mejorar el rendimiento cognitivo a corto plazo. El HIFT también podría ser interesante para los individuos sedentarios con poca motivacion y tiempo limitado para hacer ejercicio, ya que se ha reportado una mayor motivacion intrinseca y mayor disfrute del ejercicio que una actividad de tipo aeróbico moderado (Wilke, et al. 2020). No se investigo la sosteníbilidad de la mejora de la PC, con evaluaciones de seguimiento adicionales, por lo que investigar los cambios 5, 10 15, 30, 60 minutos después o incluso 2, 6, 12, 24 horas después del entrenamiento a largo plazo es una tarea pendiente.No incluyó una comparación con una sesión de entrenamiento aeróbico o de resistencia con pesas de intensidad equivalente, es decir de alta intensidad. Solamente HIFT fue de alta intensidad, pero el ejercicio aeróbico estuvo en el limite superior de ejercicio de baja intensidad, con lo que la diferencia en intensidad pudo haber afectado la comparación. Alcaraz, P. E., Sánchez-Lorente, J., & Blazevich, A. J. (2008). Physical performance and cardiovascular responses to an acute bout of heavy resistance circuit training versus traditional strength training. In Journal of Strength and Conditioning Research (Vol. 22, pp. 667-671): J Strength Cond Res.Ben-Zeev, T., Hirsh, T., Weiss, I., Gornstein, M., & Okun, E. (2020). The Effects of High-intensity Functional Training (HIFT) on Spatial Learning, Visual Pattern Separation and Attention Span in Adolescents. In Frontiers in Behavioral Neuroscience (Vol. 14, pp. 577390): Frontiers Media S.A.Brisswalter, J., Collardeau, M. & René, A. Effects of acute physical exercise characteristics on cognitive performance. Sports Med. 32, 555–566 (2002).Browne, S. E. et al. Effects of acute high-intensity exercise on cognitive performance in trained individuals: a systematic review. Progr. Brain. Res. 234, 161–187 (2017).Buckley, S., Knapp, K., Lackie, A., Lewry, C., Horvey, K., Benko, C., . . . Butcher, S. (2015). Multimodal high-intensity interval training increases muscle function and metabolic performance in females. In Applied Physiology, Nutrition and Metabolism (Vol. 40, pp. 1157-1162): Appl Physiol Nutr MetabChang, Y. et al. The effects of acute exercise on cognitive performance: a meta-analysis. Brain. Res. 1453, 87–101 (2012).Feito, Y., Heinrich, K. M., Butcher, S. J., & Poston, W. S. C. (2018). High-Intensity Functional Training (HIFT): Definition and Research Implications for Improved Fitness. In Sports (Basel, Switzerland) (Vol. 6, pp. 76): MDPI AGGarcía-Suárez, P. C., Rentería, I., Moncada-Jiménez, J., Fry, A. C., & Jiménez-Maldonado, A. (2020). Acute Systemic Response Of BDNF, Lactate and Cortisol to Strenuous Exercise Modalities in Healthy Untrained Women. In Dose-response : a publication of International Hormesis Society (Vol. 18, pp. 1559325820970818): SAGE Publications Inc.Heinrich, K. M., Patel, P. M., O'Neal, J. L., & Heinrich, B. S. (2014). High-intensity compared to moderate-intensity training for exercise initiation, enjoyment, adherence, and intentions: an intervention study. BMC Public Health, 14, 789. doi:10.1186/1471-2458-14-789Menz, V. et al. Functional vs running low-volume high-intensity interval training: effects on VO2max and muscular endurance. J. Sports Sci. Med. 18, 497–504 (2019).Murawska-Ciałowicz, E., de Assis, G. G., Clemente, F. M., Feito, Y., Stastny, P., Zuwała-Jagiełło, J., . . . Wolański, P. (2021). Effect of four different forms of high intensity training on BDNF response to Wingate and Graded Exercise Test. In Scientific Reports (Vol. 11, pp. 8599): Nature Research.Ogoh, S. & Ainslie, P. N. Cerebral blood flow during exercise: mechanisms of regulation. J. Appl. Physiol. 107, 1370–1380 (2009).Querido, J. S. & Sheel, A. W. Regulation of cerebral blood flow during exercise. Sports Med. 37, 765–782 (2007).Tsai, C. et al. Executive function and endocrinological responses to acute resistance exercise. Front Behav Neurosci. 8, 283 (2014).Wilke, J. et al. Effects of high-intensity functional circuit training on motor function and sport motivation in healthy, inactive adults. Scand. J. Med. Sci. Sports 29, 144–153 (2019).Wilke, J., Stricker, V., & Usedly, S. (2020). Free-Weight Resistance Exercise Is More Effective in Enhancing Inhibitory Control than Machine-Based Training: A Randomized, Controlled Trial. In Brain sciences (Vol. 10, pp. 1-10): MDPI AG.Yarrow, J. F., White, L. J., McCoy, S. C. & Borst, S. E. Training augments resistance exercise induced elevation of circulating brain derived neurotrophic factor (BDNF). Neurosci. Lett. 26, 161–165 (2010).

デンマーク・オーフス大のDANDRITE研究所で来夏独立予定の北沢太郎さん(@kitazawa_taro, 現FMI Rijliラボ)をゲストに、これまでのキャリア・興味の変遷、FMI、ヨーロッパでの就活などなどについて話しました。(11/4収録　* 初のin-person収録ということで宮脇はお休み) Shownotes: 北沢ラボ(2022夏open予定、現在メンバー募集中)@DANDRITEのHP Aarhus大学DANDRITE (#20/21 米原さん回も参照) Nordic-EMBL EMBL 長野県の松本深志 東大医のPhD-MDコース 栗原裕基教授 Single-cell レベルでChIPseqできるCut&Run Hoxa2論文(Kitazawa et al., Developmental Biology, 2015) 鼓膜進化論文(Kitazawa et al., Nature Comm, 2015) 鼓膜論文、結局内容についてちゃんと話してなかったです汗。哺乳類(=マウス)と双弓類(爬虫類・鳥類=ニワトリ)でEdn1-Dlx5/6経路を阻害して下顎→上顎ホメオティック変異を起こさせると、マウスでは鼓膜が消失するのに対してニワトリでは鼓膜の重複が起きる。これは鼓膜の発生が全く異なる発生機構の下流にあることを示し、鼓膜の収斂進化の実験的証拠となった。理研のプレスリリースがとても分かりやすい。(北沢注) あと、日経サイエンス(Scientific American日本語版)2015年8月号でも特集されました。他にも結構新聞で取り上げられたなー(北沢注) 神戸理研　倉谷滋先生 怪獣生物学 動物進化形態学 初版(2004年) 新版(2017年) 2004年Verに鼓膜は課題として述べられていて、2017年Verで僕のアンサーがアップデートされています！ (北沢注) Gauppの論文の例 Arch. Anat. Physiol. Suppl. 1, 416 (1912). Filippo Rijli Maryline Minoux et al., Science, 2017 ChIPmentationのNat Methodsペーパー FMIのSAB (Scientific Advisory Board) ERC: EU+αのグラント。PIがステージ(Starting/Consolidator/Advanced)に応じて取るprestigiousな研究費。(日本で言うとさきがけ〜CRESTに相当だが額は倍くらいある) コンディショナルオファー: 独立するためのお金を外部から取ってきたらスペースはあげるよ、というタイプのジョブオファー。一方のオープンポジションはオファーが出たらラボを立ち上げるための資金(スタートアップ)は基本的にもらえる。 えくせれんつぁ: スイスSfNの独立用グラント Eccellenza(1,000,000CHF=1億2000万くらい) えみーねたー: ドイツDFGの独立用グラント Emmy Norther *RO1に関する言及はテキトーだと思うので注意。 Editorial notes: 出だしで北沢さんが敬語なのがおもろい。Part1では神経科学的な内容をほぼしてませんが、Part2では多少します！ (萩原) 対面でしゃべっていると段々砕けていって、ちょいちょいフランクすぎる感じになってしまったかも。こういう収録は初めてでしたが、自分の語り段取りの悪さや言葉足らずな点が目立ちますね、難しい！(北沢) 今回の自分のcontributionはshownotes作りを5%やった程度ですw　(宮脇)

Dr Rob reveals several new studies that are challenging the fundamental assumptions that underlie the neo-Darwinian synthesis. Specifically. the 'central dogma of molecular biology' (the thought that information only flows from DNA to RNA to protein) and the Weismann barrier (the thought that only the DNA 'information' in sperm and egg cells is inherited) are both wrong. Recent revelations have shown us that sperm actively absorb and use body-cell-sourced RNA in the epididymis, and one polymerase uses RNA templates in a newly discovered DNA repair system. Neither of these are supposed to be true. Can a vague idea from the 19th century withstand the assault of 21st century knowledge? Hardly. The simplifying assumptions made by Darwin and his contemporaries no longer hold up. Notes and links: Main article: Carter R., The barrier has been breached! Making a fool out of Professor Wise-man, Creation.com, 7 September 2021. Wilhelm D, Palmer S, Koopman P, Sex determination and gonadal development in mammals, Physiol. Rev. 87(1):1–28, 2007; doi: 10.1152/physrev.00009.2006. Crow JF, Age and sex differences on human mutation rates: an old problem with new complexities, J. Radiat. Res. 47(Suppl.):B75–B82, 2006; doi: 10.1269/jrr.47.b75. James ER, et al., The role of the epididymis and the contribution of epididymosomes to mammalian reproduction, Int. J. Mol. Sci. 21:5377, 2020; doi: 10.3390/ijms21155377. Chandramouly G, et al., Polθ reverse transcribes RNA and promotes RNA-templated DNA repair. Science Advances 7(24):eabf1771; doi: 10.1126/sciadv.abf1771. See also the press release from Thomas Jefferson University “New discovery shows human cells can write RNA sequences into DNA”, Phys.org, 11 June 2021. King TE, et al., Africans in Yorkshire? The deepest-rooting clade of the Y phylogeny within an English genealogy, Eur J. Hum. Genet. 15:288–293, 2007; doi: 10.1038/sj.ejhg.5201771. Filming locations: Kennesaw National Battlefield Park and Kennesaw Memorial Park.

Annu. Rev. Physiol. 2013. 75:685–705 Nutrients. 2020 Mar; 12(3): 622 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message Support this podcast: https://anchor.fm/dr-daniel-j-guerra/support

喝冰水會得癌症、會導致肝臟堆積脂肪、會對腸胃不好嗎？這邊找了一些研究報告大家可以參考： 資料來源： Wong JMW, Ebbeling CB, Robinson L, Feldman HA, Ludwig DS. Effects of Advice to Drink 8 Cups of Water per Day in Adolescents With Overweight or Obesity: A Randomized Clinical Trial. JAMA Pediatr. 2017 May 1;171(5):e170012. Brown CM, Dulloo AG, Montani JP. Water-induced thermogenesis reconsidered: the effects of osmolality and water temperature on energy expenditure after drinking. J Clin Endocrinol Metab. 2006 Sep;91(9):3598-602. Thornton SN. Increased Hydration Can Be Associated with Weight Loss. Front Nutr. 2016 Jun 10;3:18. Stookey JJ. Negative, Null and Beneficial Effects of Drinking Water on Energy Intake, Energy Expenditure, Fat Oxidation and Weight Change in Randomized Trials: A Qualitative Review. Nutrients. 2016 Jan 2;8(1). pii: E19. Zoeller, R.T., N.Kabeer and H.E. Albers.1990. Cold exposure elevates cellular levels of messenger ribonucleic acid encoding thyrotropin-releasing hormone in paraventricular nucleus despite elevated levels of thyroid hormones. Endocrinology 127(6); 2955-2962 Wu S.Y., J.S. Stern, D.A. Fisher and Z. Glick. 1987. Cold-induced increase in brown fat thyroxine 5'-monodeiodinase is attenuated in Zucker obese rat. Am. J. Physiol. 252:E63-E67 Harrop, J.S., Ashwell and M.R. Hopton. 1985. Circannual and within-individual variation of thyroid function tests in normal subjects. Ann. Clin. Biochem. 22:371-375 Gong, D.W., Y.He, M.Karas and M. Reitman. 1997. Uncoupling protein-3 is a mediator of thermogenesis regulated by thyroid hormone, β3-adrenergic agonists, and leptin. J. Biol. Chem. 272:24129-24132 Westerterp-Plantenga, MS., WD. Van Marken Lichtenbelt, H. Strobbe and P. Schrauwen. 2002. Energy metabolism in humans at lowered ambient temperature. Eur.J.Clin.Nutr. 56:288-296 各位朋友，若您有醫美、減肥、健康相關問題，請直接到「景升診所」官網任一頁面留言，或用下列方法與我們聯絡： 直接撥打24小時專線 +886-931919066 Line id=“Gscline" WeChat id=“Gscline" 哈囉，大家好: 我們有幾個不同的頻道： Grand Health 大健康 （健康加財富、知足就是福）https://goo.gl/6EGLMd Grand Beauty 大醫美 （好好愛自己、就從現在起）https://goo.gl/g1E1rq Grand Touring 大旅遊 （大叔向前跑、永遠沒煩惱）https://goo.gl/7HN4bk 歡迎大家欣賞，喜歡就請按個讚，想獲取最新訊息就按「訂閱」吧！ 我們會提供更多更新的知識和訊息給大家。 感謝以下單位的幫助： ✪景升診所 https://www.genesis-clinic.org https://www.gscline.com ✪愛瘦美官網 https://www.isome.com.tw ✪邱醫師醫話園 https://www.okclinic.gscline.com ✪隆乳 https://www.gscline.com/ifatgraft/breast-adsc-htm ✪減肥 https://www.gscline.com/islimcenter-htm/fat-htm ✪自體脂肪隆乳 https://www.gscline.com/ifatgraft/breast-adsc-htm ✪瘦臉 https://www.gscline.com/ilipolysis-htm/fll-face-htm ✪瘦手臂 https://www.gscline.com/ilipolysis-htm/fll-arm-htm ✪瘦小腹 https://www.gscline.com/ilipolysis-htm/fll-abdomen-htm ✪瘦腿 https://www.gscline.com/ilipolysis-htm/fll-leg-htm ✪瘦大腿 https://www.gscline.com/ilipolysis-htm/fll-thigh-htm ✪抽脂 https://www.gscline.com/liposuction-new-technique/fat_liposuction-htm ✪男性女乳 https://www.gscline.com/ihair-htm/fll-gynecomastia-htm ✪狐臭 https://www.gscline.com/ihair-htm/laserhyperhidrosis-htm

Before we begin, we would like to clarify something - Branched chain amino acids are ESSENTIAL AMINO ACIDS (EAAs). In fact, the BCAAs are just 3 of the 9 EAAs. But please note, an EAA supplement should contain an abundance of BCAAs, otherwise it is not a full spectrum EAA supplement.  If you are interested in how to get the most out of EAA and BCAA supplements, listen on as we explain the science behind essential amino acids as performance enhancing agents.  We will talk about the follow:What are the EAAs?  So why have a standalone BCAA supplement?  What makes BCAAs so “special”? BCAAs and Brain Function Immune Function Muscle Recovery and Muscle WastingIf you want to maximize buildingWhen is the best time to take BCAAs and EAAs? References: Curzon G, Friedel J, & Knott PJ (1973). The effect of fatty acids on the binding of tryptophan to plasma protein. Nature242, 198-200. Blomstrand E (2006). A role for branched-chain amino acids in reducing central fatigue. J Nutr136, 544S-547S. Blomstrand E, Hassmen P, Ek S, Ekblom B, & Newsholme EA (1997). Influence of ingesting a solution of branched-chain amino acids on perceived exertion during exercise. Acta Physiol Scand159, 41-49. Calder PC. Branched-chain amino acids and immunity. J Nutr. 2006 Jan;136(1 Suppl):288S-93S  Shimomura Y, Yamamoto Y, Bajotto G, Sato J, Murakami T, Shimomura N, Kobayashi H, & Mawatari K (2006). Nutraceutical effects of branched-chain amino acids on skeletal muscle. J Nutr136, 529S-532S. Blomstrand E, Eliasson J, Karlsson HK, & Kohnke R (2006). Branched-chain amino acids activate key enzymes in protein synthesis after physical exercise. J Nutr136, 269S-273 Jackman SR, Witard OC, Philp A, Wallis GA, Baar K, Tipton KD. Branched-Chain Amino Acid Ingestion Stimulates Muscle Myofibrillar Protein Synthesis following Resistance Exercise in Humans. Frontiers in Physiology. 2017;8:390;  Tipton K. D., Rasmussen B. B., Miller S. L., Wolf S. E., Owens-Stovall S. K., Petrini B. E., et al. Timing of amino acid-carbohydrate ingestion alters anabolic response of muscle to resistance exercise. Am. J. Physiol. Endocrinol. Metab. 281, E197–E206; 2001; 

Treinos com elásticos podem dar os mesmos resultados que treinos em academias. Artigos citados:Gentil P, Ramirez-Campillo R and Souza D (2020) Resistance Training in Face of the Coronavirus Outbreak: Time to Think Outside the Box. Front. Physiol. 11:859. doi: 10.3389/fphys.2020.00859Souza D, Barbalho M, Vieira CA, Martins WR, Cadore EL, Gentil P (2019). Minimal dose resistance […]

Treinos com peso corporal, no estilo calistenia, dão os mesmos resultados que treinar em academia Artigos citados: Gentil P, Ramirez-Campillo R and Souza D (2020) Resistance Training in Face of the Coronavirus Outbreak: Time to Think Outside the Box. Front. Physiol. 11:859. doi: 10.3389/fphys.2020.00859 (veja em https://www.paulogentil.com/2020/07/0…)Calatayud J, Borreani S, Colado JC, Martin F, Tella […]

A falta de sono gera uma série de problemas, no entanto, o exercício pode ajudar. Artigo citado:de Souza JFT, Dáttilo M, de Mello MT, Tufik S and Antunes HKM (2017) High-Intensity Interval Training Attenuates Insulin Resistance Induced by Sleep Deprivation in Healthy Males. Front. Physiol. 8:992. doi: 10.3389/fphys.2017.00992

Cześć! W dzisiejszym odcinku dowiesz się co można robić na najwyższej górze świata (i nie chodzi nam tylko o jej zdobycie), czy Adrian planuje dołączyć do sekty i co zachęca go do zdobycia Śnieżki w samych szortach! Ponadto rozmawiamy o tym jak to jest się nie bać, jak długo człowiek może wytrzymać w kąpieli lodowej (jak tylko zrobi ten jeden prosty trick... a właściwie to trzy), a także co wspólnego ma poznawanie mózgu i zderzanie samochodów! Odcinek zawiera śladowe ilości zmiany biegów. Do usłyszenia! Adrian o Mount Everest, wpływie wysokości na organizm człowieka i metodzie Wima Hoffa: 1:04:05 Patryk o pacjentce SM-046: 11:48 Źródła internetowe: https://www.wimhofmethod.com www.youtube.com/watch?v=VaMjhwFE1Zw&list=WL&index=49&t Bibliografia M. P. W. Grocott et al., N. Engl. J. Med. 360, 2009, 140-149 T. O. Nelson et al., J Exp. Psychol. Gen. 119, 1990, 367-374 J. Ke et al., Exerc. Sport Sci. Rev. 14, 1986, 269-302 J. B. West, J. Appl. Physiol. 102, 1985, 2398-2399 O. Muzik, NeuroImage 172, 2018, 632-641 M. Kox, Proceedings of the National Academy of Sciences 111, 2014, 7379-7384 R. Adolphs et al., Nature 372, 1994, 669-672 R. Adolphs et al., J. Neurosci. 15, 1995, 5879-5891 R. Adolphs et al., Nature 393, 1998, 470-474 J.S. Feinstein et al., Curr Biol. 21, 2011, 34-38 J.S. Feinstein et al., Nat. Neurosci. 16, 2013, 270-272 D. Tranel et al., Cogn. Neuropsychiatry 11, 2006, 219-232

One key question we ask ourselves as coaches at FasCat, is if the athlete is responding to the training we have prescribed. Aka, are they getting faster? Our favorite “experiment” to answer this question is a good old fashioned 20 minute power based field test, which is free and can be conducted anywhere and anytime appropriate. Reality Cycling In a former life and career, I conducted hundreds of experiments as a research scientist in biotechnology and academic medical research laboratories designed to answer specific questions about the research projects I was working on. Spinal cord research, cancer, and novel cancer cures to name a few.  At FasCat, we still perform “experiments” designed to evaluate our athletes' current physiology as it relates to their cycling performance.  Still to this day the most practical, most relevant test of all is a 20 minute power based field test. With the exception of the gold standard, 40k time trial. 1463Increase your FTP with our Hill Climb Intervals Training Plan. In the past we have conducted MLSS tests in an exercise physiology lab, but the reality is that cyclists need to test two to three times per year which is cost prohibitive and not practical for many athletes.  Plus indoor power tends to be slightly less that outdoor power.  A properly conducted field test cuts to the core of cycling performance and gives a great physiological assessment of the athlete (1), making it an indispensable tool for our coaches or the self coached athlete. How Do I Conduct a Field Test? In essence, a 20 minute power based field test is riding as fast as hard as you can for exactly 20 minutes.  Just like a 20 minute time trial. Record your average power output and use that number as a benchmark and to determine your wattage based zones*.  When available we'll recommend a steady grade hill free of stop signs, descents and any section of road that requires the athlete to stop pedalling.  Ideally a 2-3% steady grade hill like this Strava segment.  Steeper climbs tend to bog athletes' cadence down which skews the test results.  Conversely, some athletes make greater power uphill than they can on the flats. Whichever you choose, it is absolutely imperative that you ensure your test is repeatable, accurate and reliable. Apples – apples. Here's how: For the road cyclist and mountain biker an all out effort similar to your time trial pace of 20 minutes elicits a physiological response that has been found to be “the single greatest determinant of cycling performance in mass start cycling events” (1).  We have experimented with 60 minute Field Tests and honestly not that many athletes can sustain that sort of mental effort for the full 60 minutes.  If they can its a mental match we don't want to burn.  On the other hand if we know the athlete can do a 60 minute field test once a year, it is the coaches discretion to prescribe one.   It is especially beneficial to compare 60 minute field test data to ~ 60 minute 40k time trial data. When choosing the roads for your field test let the terrain you have available dictate the specifics of your test (working within the 20 min range). After all, going for it from the bottom of a climb all the way to the top is more stimulating than working off your stopwatch. It may even be specific to your target event(s). For instance, a climber targeting a race with a decisive climb will want to specifically perform their test on a climb similar to the one found in the race. Heck, if you live nearby the race course, test on the race course! Conversely you may not even see a climb longer than one or two minutes where you live. That's cool; then find a stretch of road to measure how far you can ride in 20 minutes. If this is the case, pay special attention to the wind and humidity which will affect your aerodynamics and thus time. As long as you come back to the very same piece of road and start from the very same spot, under the same test conditions, your test will be repeatable. *We take the average 20 minute power and subtract 5 – 10% to arrive at an athlete's 60 minute “Functional Threshold Power” or FTP. As a generally rule of thumb we use 5% for slow twitch aerobic athletes and 10% for athletes that have a well developed anaerobic system.  We'll subtract 7.5% if we don't know about the athlete's anaerobic capacity. Repeatability Whatever you have nearby, find a stretch of road free of stops signs, intersections and corners — anything that would slow you down. In essence: go as hard as you can! Don't hold back one bit, go for it! Now here's the catch: remember everything about this test and duplicate it for your next test. Items to keep the same (& ensure repeatability) include: Your powermeter! Calibrated of course. Different powermeters unfortunately produce different results Your bike: weight (including water bottles), body position, tires, tire pressure. Your kit: jersey, shorts, helmet – – essentially you want to have the same aerodynamic characteristics from test to test. Wind and weather conditions: test on a windless day under the same humidity – air density affects aerodynamics too! Temperature: avoid testing between extreme temperature differences. Come into the test rested, properly fueled, well hydrated with tons of motivation (you gotta go full gas!) Perform the exact same warm up before each field test. In a nutshell keep everything the same except for your fitness – that is the variable you are testing for. Being able to compare tests and controlling for all other variables except your physiology or fitness allows you and your coach to interpret the efficacy of your training. These details may seem picky but are necessary to draw accurate comparisons. Your results: Test at the beginning of your training and then again after 8-12 weeks to measure your improvement. If your power goes up, guess what? Your training is working, keep going.  If your power goes down or stays the same, guess what? Your training is not working and you need to change what you are doing.  Its as simple as that. All of our Six Week $49 Training Plans culminate with a field test so you can measure how much faster you've become! Test not once, but twice, or more If you have a new powermeter or are beginning a training program, perform a “baseline” field test for two reasons: • To determine your wattage based training zones • To establish a benchmark to measure future improvement For a good test ‘performance', approach the day with a minimum of 24 hours rest and go absolutely as hard as you can during the test.  If you don't, the results will be inconclusive.  Record the average power and continue with your next training cycle. Come back to the very same field test in 6-8 weeks under the same rested conditions and go for it again. By comparing the two average power outputs,  you will be able to draw useful conclusions about your training. i.e. is it working? Test periodically throughout the year (we recommend no more than 3 times*) and carefully record your results in your training log. This will paint a big picture that is extremely useful when plotting out your next move and planning your next winning season. Regular testing is THE BEST way to track performance and we do not recommend using mean maximal, mFTP or power profile charts that cull non “as hard as you can go” power outputs. By performing 20 minute tests, you'll also be able to compare this data with race data.  For example, time trials where you went as hard as you could for 20 minutes or breakaways and long climbs. Summary • Go as hard as you can for the full 20 minutes • Upload your data and analyze the average power output • Make sure the test is 100% repeatable to eliminate all variables except your average power output improvement • For indoor 20 minutes tests, see our indoor cycling 20 minute tip Finally, testing yourself is a great start, but remember the ultimate measure of performance is performance itself. So get out there in a race, go hard, and duke it out!  For further reading, please read the “Determining Threshold Power” training tip on VeloNews. Reference E.F. Coyle, A.R. Coggan, M.K. Hopper and T.J. Walters, “Determinants of endurance in well-trained cyclists.” J Appl. Physiol 64:2622-2630, 1988 Copyright © 2020 FasCat Coaching – all rights reserved. Join our *FREE* Athlete Forum to nerd out with FasCat coaches and athletes about your FTP, race data, power based training, or anything related to going fast on the bike! Comments The post A 20 Minute Power-Based Field Test appeared first on FasCat.