Podcasts about Curcuma

durée : 00:43:56 - Le curcuma, épice miracle ? avec François Tournay, spécialiste santé au naturel - Infusion, poudre ou gélules : de nombreux auditeurs utilisent le curcuma pour soulager douleurs et troubles digestifs. François Tournay explique pourquoi cette plante est un allié santé incontournable.

Curcuma ist lebertoxisch in bereits sehr niedrigen Mengen und kann unserer Gesundheit großen Schaden anrichten - so zumindest die Kernaussagen neuster Beiträge des NDR und der Tagesschau auf Social Media.Die Panik ist groß, die Sorge berechtigt - Doch was ist wirklich dran an dieser neuen ”wissenschaftlichen” Erkenntnis zum Curcuma bzw. Curcumin?Höchste Zeit, dass sich Experten diesem Thema widmen und dass wir dieses Thema tatsächlich wissenschaftlich beleuchten, es ins korrekte Verhältnis setzen und echte wissenschaftliche Aufklärungsarbeit betreiben.Viel Spaß beim Hören und noch mehr Erfolg bei der Umsetzung!➜ Zu meinem Kalorien- & Makrorechnerhttp://90tage.de/kalorien➜ In 90 Tagen zur besten Form deines Lebenshttps://90tage.de/➜ Fettverlust Fibel hier Gratis sichernhttps://fettverlust.de/➜ Home Fit Fibel hier Gratis sichernhttps://home-fit.de/Instagram | Facebook | YouTube | Quantum Leap Fitness

Curcuma & Douleurs Inflammatoires des Sportifs

Curcuma, Spezia Magica: Benefici, Proprietà E Indicazioni!Scopri le proprietà della curcuma e i suoi benefici per la salute. Una spezia ricca di sorprese.#breakingnews #ultimenotizie #notiziedelgiorno #notizie #cronaca #asiatica #benefici #controindicazioni #curcuma #indicazioni #magica #preziosa #proprieta #spezia

REDIFF - Cette épice jaune d'or est utilisée depuis des millénaires comme condiment dans la cuisine indienne et asiatique. On lui reconnaît des vertus médicinales. Et depuis quelques décennies, elle fait l'objet de nombreuses recherches scientifiques. Les explications d'Aline Perraudin.

A travers le hors-série « La grande histoire des mers », Le Vif L'express rend hommage à l'or bleu. Source de vie et d'émerveillement, les mers et océans sont aussi le théâtre des grandes aventures fondatrices du monde actuel. Explorations, conquêtes, commerces… leur domination a été un enjeu majeur dans les luttes que se sont livrées les grandes puissances depuis l'Antiquité. On évoque ces moments clé de l'histoire avec Philippe Berkenbaum, journaliste et concepteur du hors série Sujets traités : mer, épices, safran coton,vanille, curcuma, esclaves, Pondichery, Inde, mers ,océans Merci pour votre écoute Un Jour dans l'Histoire, c'est également en direct tous les jours de la semaine de 13h15 à 14h30 sur www.rtbf.be/lapremiere Retrouvez tous les épisodes d'Un Jour dans l'Histoire sur notre plateforme Auvio.be : https://auvio.rtbf.be/emission/5936 Et si vous avez apprécié ce podcast, n'hésitez pas à nous donner des étoiles ou des commentaires, cela nous aide à le faire connaître plus largement.

The longevity research world is exploding right now, it's so exciting and the technology is advancing in leaps and bounds and we are able now to discover faster than ever before thanks to AI and co to test more molecules that can impact human health than ever before in the history of mankind. What would have taken years now takes weeks or months. In this episode I talk to Michael Antonelli CEO and founder of Healthgevity. Michael is a master formulator who has spent decades in the anti-ageing and longevity space learning at the feet of many masters and who is at the forefront of working with companies at the cutting edge in peptide and bioactive ingredient development. All his formulations are science backed with clinical research and I was excited to learn about something of these novel molecules Introduction to Healthgevity and its CEO, Michael Antonelli Overview of Healthgevity's approach: merging clinical research, AI, and medical expertise Exploring the importance of longevity in today's society Michael Antonelli's journey and motivation behind founding Healthgevity The role of cutting-edge science in developing longevity supplements How Healthgevity collaborates with clinical practitioners and doctors Deep dive into Healthgevity's science-backed formulations Examples of specific ingredients and their benefits in promoting longevity The impact of AI in optimizing formulations and personalizing supplementation Addressing common misconceptions about longevity supplements Future prospects and advancements in the longevity industry   BIO   Throughout a career spanning over 17 years, Michael passionately devoted himself to pioneering methods aimed at enhancing longevity, optimizing healthspan, and elevating overall quality of life. His focus revolves around collaborating with leading healthcare professionals, researchers, and other likeminded healthcare leaders to create natural solutions that elevate patient outcomes. Michael utilizes his past experiences that integrates a diverse range of therapies and services, spanning from precision diagnostics to practice management strategies, hormone optimization, nutritional supplements, and leveraging peptides. Previous roles included Chief Innovation Officer, Executive Director, and Business Development for leading companies within the healthcare industry before founding Healthgevity. His expertise extends beyond conventional approaches, emphasizing holistic well-being and personalized care as essential components to any successful medical practice. By championing novel methodologies and innovative technologies, Michal facilitates transformative changes within the healthcare landscape, fostering advancements that positively impact both practitioners and the individuals they serve.  Michael continues to remain dedicated to the pursuit of innovative strategies that enhance health and vitality while reshaping the paradigms of healthcare.   Some of the products mentioned in this podcast:   CARDIO NAD+ Vascular health and aging are the most important health care problem in the world today. Healthy aging requires healthy arteries and a healthy heart. Cardio NAD+ is a state-of-the-art solution which uses the most novel ingredients available to help optimize cardiovascular health. As one of the most important systems in your body, we have designed this combination to be synergistic to the many different areas of cardiovascular health while demonstrating cardioprotective effects including the emerging connection between NAD+ and heart health. Featured Supportive Benefits: Improves net NAD+ status by supporting both its synthesis and limiting its degradation Supports healthy blood pressure Improves vascular aging and endothelial function Supports healthy fibrinolytic activity and clotting function Promotes healthy circulation and blood flow Inhibits platelet & red blood cell aggregation Decreases blood viscosity Supports clinical measures of inflammation Supports healthy blood sugar and insulin levels Inhibits lipid peroxidation Supports healthy lipid metabolism Demonstrated reduction in various independent cardiovascular risk factors   Resolve+ Resolve+ contains numerous compounds that have been found to reduce the inflammatory response by targeting a variety of mechanisms.  Acmella oleracea ("jambu") is sourced from Sardinia, Italy and rich in alkylamides mainly represented by spilanthol. Its flowers are widely used in folk medicine to treat toothache due to tingling, numbness, and local anesthesia caused in the mouth.  Acmella oleracea has been shown to be active in fatty acid amide hydrolase (FAAH) inhibition the enzyme responsible for the degradation of fatty acid amides and cannabinoid type 2 (CB2) activation.  There are almost 100 studies suggesting the supportive potential for anti-inflammatory, antioxidant, and analgesic effects of Acmella. Studies reported in this review confirmed activities of Acmella, postulating that transcription factors of the nuclear factor-κB family (NF-κB) trigger the transcription iNOS and COX-2 and several other pro-inflammatory mediators, such as IL-6, IL-1β, and TNF-α. Curcumin, a natural polyphenolic compound derived from turmeric (Curcuma longa L.), has been well documented to exhibit various health benefits. There have been many claims on the health benefits of curcumin on neurological, cardiovascular, lung, metabolic, and liver function, mainly through its anti-inflammatory and antioxidant properties. Despite its promising potential, the clinical application of curcumin has been limited due to its low bioavailability. To enhance curcumin absorption, we are the first to feature Theracurmin Super® 85X, a proprietary curcumin utilizing the latest technology that transforms standard curcumin into an amorphous structure. Theracurmin Super® 85X uses the latest technology to transform regular curcumin particles into a more bioavailable structure. This is done by splitting curcumin particles' crystal structure amorphous, therefore, making it easily absorbed and bioavailable to maximize its supportive potential. Tetrahydrocurcumin (4-HC) is the key bioactive derivative of curcumin, it's also given credibility as the engine behind all that curcumin brings to the table. With a newfound ability to extract and isolate the compound, research has even seen tetrahydrocurcumin outperform its parent compound in several tests of its capabilities. Researchers have also confirmed that 4-HC attenuated pro-inflammatory indicators like interleukin-1, interleukin-6, TNF-⍺, and prostaglandin E2.  After reviewing the data, we found many advantages to infuse tetrahydrocurcumin as CurcuPrime® stacked with Theracurmin Super® 85X into Resolve+. Quercetin is a well-known studied dietary flavonoid ubiquitously present in various vegetables. Quercetin is known for its antioxidant activity in radical scavenging and anti-allergic properties characterized by stimulation of immune system, antiviral activity, inhibition of histamine release, decrease in pro-inflammatory cytokines, leukotrienes creation, and suppresses interleukin IL-4 production.  Multiple studies have confirmed its supportive potential as an immune modulator and its ability to support a healthy inflammatory response. It can improve the Th1/Th2 balance, and restrain antigen specific IgE antibody formation However, chemical instability, poor water solubility and low bioavailability of quercetin greatly limit its applications which is why a phytosome technology which we feature in resolve is the preferred delivery system to overcome these limitations.  This enhanced form of quercetin has been shown to be as much as 20 times better absorbed than other quercetin options.  Casperome®  boswellia phytosome is a potent extract made from the resin of Boswellia serrata trees and is also referred as Indian frankincense. Boswellia extracts have been demonstrated to be effective in the management of various inflammatory response functions including those that occur in the bowel, joints, bones, respiratory airways and in the brain. The mechanism of action that involves the modulation of the natural inflammatory response both acting on prostanoid synthesis (mPGE2S) and protein degradation (caspases), and transcription factors (Nf-κB).  We have selected Casperome® which is a highly standardized in boswellic acids to match the natural composition of boswellia, formulated with phytosome technology to achieve optimized absorption and has been validated by over 10 human studies. Perilla frutescens is an annual herb belonging to the mint family (Lamiaceae). It is mainly produced in countries like China, Japan, India, Thailand and Korea. Recently, Perilla is gaining more attention because of its medicinal benefits and phytochemical contents. The functional compounds of Perilla Seed Extract are flavonoid Aglycons – polyphenols such as Luteolin, Apigenin, Chrysoeriol, and Rosemarinic Acid. Studies have shown that Perilla seed polyphenols regulate allergic and inflammatory response due to its 5-lipoxygenase inhibitory activity and suppression potential of histamine release from mast cells. AstraGin® is a natural compound derived from the roots of two traditional Chinese herbs: Panax notoginseng and Astragalus membranaceous which contain astragaloside I, II, IV and ginsenoside Rb1. AstraGin® has been shown to provide full-spectrum gut support through enhanced absorption, microbiota and immune cell viability, and supporting a health. AstraGin® has been shown in numerous studies to increase the absorption of peptides, amino acids, fatty acids, vitamins, and phytonutrients by up regulating the absorption specific mRNA and transporters, such as SGLT1, CAT1, and GLUT4. Additionally, AstraGin® was shown to reduce intestinal inflammatory biomarker MPO, the pro-inflammatory cytokines IL-6, IL-17, and IL-1β in ulcerative colitis patients. Prime Gut Health Prime Gut Health was created because the digestive system is the foundation of getting and staying healthy. There are many benefits to an optimal digestive system such as a healthy immune system and the protection against harmful viruses, bacteria, fungi, and yeast. The ingredients selected in Prime Gut Health work together to help restore gut homeostasis and GI barrier function.    There are many benefits to taking Prime Gut Health, including:  Supports healthy GI barrier function*   Helps restore gut homeostasis* Binds and neutralizes bacterial toxins in the gut*  Promotes a healthy immune system and respiratory health* Supports digestive health and gut discomfort*  Increased nutrient absorption*  Supports gut inflammation especially within the intestinal wall*  Promotes a healthier GI environment* Promoted regularity and healthy bowel function*    WHAT MAKES PRIME GUT HEALTH SO IMPACTFUL? ImmunoLin® is the branded ingredient serum-derived bovine immunoglobulin/protein isolate (SBI) with over 40 human studies demonstrating its clinical efficacy in digestive and immune health.   SBI has been shown to be a broad-spectrum modulator of the immune system by targeting excessive or imbalanced immunity.* In addition, ImmunoLin® works by binding, neutralizing, and removing pathogenic bacteria, viruses, and other gut irritants that can lead to inflammation.* It also helps to repair the gut lining and restore gut homeostasis.*   Tributyrin (as CoreBiome®) is a postbiotic and the most important short-chain fatty acid (SCFA) for supporting digestive, gut, immune and gastrointestinal health. CoreBiome® is a unique butyrate formula intended to pass intact through the stomach and small intestine to deliver butyrate right where it's needed—the colon.  CoreBiome® supports: Delivery of butyrate to the colon where it helps maintain the integrity of your intestinal lining* Helps repair the gut lining and restore gut homeostasis*  Tight junctures in the intestinal lining*  Regularity and regulation of a normal inflammatory response* Sporebiotics:  Soil-based probiotics have been touted for their stability, ability to improve digestion, stimulate the immune system, and help maintain a healthy gut microbiota. Bacillus coagulans SNZ 1969®, Bacillus subtilis SNZ 1972 and Bacillus clausii SNZ 1971 are supported with an over 50 year history of use and over 30 human studies covering gut health, gastrointestinal discomfort, immunity against GI tract pathogens, inhibition of food borne pathogens, inhibition of bacteria causing dental carries and gingivitis along with bacterial vaginosis. AstraGin® is a 100% natural compound derived from the roots of two traditional Chinese herbs: Panax notoginseng and Astragalus membranaceous,  containing astragaloside I, II, IV and ginsenoside Rb1. AstraGin® enhances nutrient absorption by up-regulating nutrient transporters, such as CAT1, SGLT1, and FR. AstraGin® restores gut wall integrity by triggering an anti-inflammatory response and activating the mTOR pathway for rapid intestinal stem cell migration and differentiation in the inflamed intestinal mucosal barrier (epithelial cell and tight junction). AstraGin® promotes gut ecosystem homeostasis by the symbiotic effect of restoring gut wall integrity and increasing microbiota-immunity communication.  AstraGin® activates the immune system through the symbiotic effect of improved gut wall integrity and enhanced microbiota-immunity communication. AstraGin® demonstrated in a recent published human clinical trial, to improve upon a number of measurable factors relating to gut health making it an ideal addition into Prime Gut Health.  PrimeTime  Prime Time is a comprehensive blend of 12 key natural ingredients shown to have a role in supporting age management powered by industry leading 10mg's of spermidine per serving.  Prime Time has been formulated with ingredients to mimic fasting and catalyze your body's natural ability to rid itself of aged cells.  Various publications demonstrate the potential this formula will have in your longevity protocols as Prime Time was formulated to support:   Epigenetic aging*  Boosting autophagy and promote cellular renewal*  Fasting* Memory, cognition, and brain health* Cardiovascular health* Beauty from within* Mitochondria*  WHAT MAKES PRIME TIME SO IMPACTFUL? Spermidine Spermidine, a natural polyamine, plays a critical role in molecular and cellular interactions involved in various physiological and functional processes. Spermidine has been shown to modulate aging, suppress the occurrence and severity of age-related diseases, and prolong lifespan.  The concentration of spermidine declines with age, and exogenous spermidine supplementation reverses age- associated adverse changes and supports health span. Given that it interacts with various molecules, spermidine influences aging through diverse mechanisms.  Autophagy is the body's way of cleaning out damaged cells, to regenerate newer, healthier cells and is the main mechanism of spermidine. In addition, spermidine exerts its effects through other mechanisms, including anti-inflammation, histone acetylation reduction, lipid metabolism and regulation of cell growth and signaling pathways. Nicotinamide mononucleotide  Nicotinamide mononucleotide, a naturally occurring molecule present in all species.  NMN is rapidly absorbed and converted to NAD+, which evidence shows declines as we age.  In numerous studies, supplementation has increased NAD+ biosynthesis, suppressed age-related adipose tissue inflammation, enhanced insulin secretion and insulin action, improved mitochondrial function, and improves neuronal function in the brain among much more. Epigallocatechin-3-gallate (EGCG)  Epigallocatechin-3-gallate (EGCG) is the major catechin in green tea.  There is consistency in the literature about the beneficial role of green tea on senescence-related mechanisms, thanks to its scavenging properties against reactive oxygen species (ROS) and reactive nitrogen species (RNS) and its ability to stimulate autophagy  Alpha-ketoglutarate (AKG) Alpha-ketoglutarate (AKG) is a molecule involved in several metabolic and cellular pathways that declines with age. It works as an energy donor, a precursor in amino acid production, and a cellular signaling molecule, and it is a regulator of epigenetic processes.  Dihydroquercetin (Taxifolin)  Dihydroquercetin is a powerful antioxidant of plant origin that can protect cells from the harmful effects of free radicals and protect cell membranes against damage Apigenin Apigenin is a natural bioactive plant polyphenol with antioxidant, anti-inflammatory and immune system boosting properties.  It also helps to support against oxidative stress for better cellular function. Studies have shown that apigenin prevents excessive loss of NAD+ by reducing the amount of circulating CD38, allowing NAD+ stores to remain at higher, more youthful levels. Luteolin Luteolin is a flavonoid naturally found in plants. Flavonoids like luteolin have been found to have beneficial effects on human health by reducing oxidative stress.   Trimethylglycine (TMG) Trimethylglycine (TMG) is an amino acid derivative that occurs in plants and has been shown to support methylation which, in turn, supports the homocysteine levels. Taking TMG along with NMN provides the ideal balance for NAD+ production in the body.  Resveratrol  Resveratrol is part of a group of compounds called polyphenols, which act as antioxidants to protect the body against age-related conditions.The anti-aging mechanisms of resveratrol are mainly modulating oxidative stress, relieving inflammatory reaction, improving mitochondrial function, and regulating apoptosis. Resveratrol is considered for the prevention and support of aging and age-related diseases as it mimics the effects of calorie restriction.  Pterostilbene Pterostilbene is a phenolic compound in the same family as resveratrol and is present in small amounts in a large variety of foods and beverages like blueberries or red wine. Multiple studies confirm pterostilbene's remarkable anti-aging effects. Cell and animal studies have shown that pterostilbene can extend the lifespan of various animal models of human longevity by regulating three major pathways linked to longevity: mammalian target of rapamycin (mTOR), AMP-activated protein kinase (AMPK), and sirtuins Bergamot Bergamot (Citrus bergamia) is a type of citrus fruit native to Italy. It has been shown that bergamot juice exerts antioxidant, cardioprotective properties and antisenescence effects.  AstraGin®  AstraGin® is a natural compound derived from the roots of two traditional Chinese herbs: Panax notoginseng and Astragalus membranaceous. AstraGin® increases the absorption of peptides, amino acids, fatty acids, vitamins, and phytonutrients by up-regulating absorption-specific m RNA and transporters such as SGLT1, CAT1, and GLUT4. Check out all the healthgevity products in our shop.    Personalised Health Optimisation Consulting with Lisa Tamati Lisa offers solution focused coaching sessions to help you find the right answers to your challenges. Topics Lisa can help with:  Lisa is a Genetics Practitioner, Health Optimisation Coach, High Performance and Mindset Coach. She is a qualified Ph360 Epigenetics coach and a clinician with The DNA Company and has done years of research into brain rehabilitation, neurodegenerative diseases and biohacking. She has extensive knowledge on such therapies as hyperbaric oxygen,  intravenous vitamin C, sports performance, functional genomics, Thyroid, Hormones, Cancer and much more. She can assist with all functional medicine testing. Testing Options Comprehensive Thyroid testing DUTCH Hormone testing Adrenal Testing Organic Acid Testing Microbiome Testing Cell Blueprint Testing Epigenetics Testing DNA testing Basic Blood Test analysis Heavy Metals  Nutristat Omega 3 to 6 status and more  Lisa and her functional medicine colleagues in the practice can help you navigate the confusing world of health and medicine . She can also advise on the latest research and where to get help if mainstream medicine hasn't got the answers you are searching for whatever the  challenge you are facing from cancer to gut issues, from depression and anxiety, weight loss issues, from head injuries to burn out to hormone optimisation to the latest in longevity science. Book your consultation with Lisa    Join our Patron program and support the show Pushing the Limits' has been free to air for over 8 years. Providing leading edge information to anyone who needs it. But we need help on our mission.  Please join our patron community and get exclusive member benefits (more to roll out later this year) and support this educational platform for the price of a coffee or two You can join by going to  Lisa's Patron Community Or if you just want to support Lisa with a "coffee" go to  https://www.buymeacoffee.com/LisaT to donate $3   Lisa's Anti-Aging and Longevity Supplements  Lisa has spent years curating a very specialized range of exclusive longevity, health optimizing supplements from leading scientists, researchers and companies all around the world.  This is an unprecedented collection. The stuff Lisa wanted for her family but couldn't get in NZ that's what it's in her range. Lisa is constantly researching and interviewing the top scientists and researchers in the world to get you the best cutting edge supplements to optimize your life.   Subscribe to our popular Youtube channel  with over 600 videos, millions of views, a number of full length documentaries, and much more. You don't want to miss out on all the great content on our Lisa's youtube channel. Youtube   Order Lisa's Books Lisa has published 5 books: Running Hot, Running to Extremes, Relentless, What your oncologist isn't telling you and her latest "Thriving on the Edge"  Check them all out at  https://shop.lisatamati.com/collections/books   Perfect Amino Supplement by Dr David Minkoff Introducing PerfectAmino PerfectAmino is an amino acid supplement that is 99% utilized by the body to make protein. PerfectAmino is 3-6x the protein of other sources with almost no calories. 100% vegan and non-GMO. The coated PerfectAmino tablets are a slightly different shape and have a natural, non-GMO, certified organic vegan coating on them so they will glide down your throat easily. Fully absorbed within 20-30 minutes! No other form of protein comes close to PerfectAminos Listen to the episode with Dr Minkoff here:    Use code "tamati" at checkout to get a 10% discount on any of their devices.   Red Light Therapy: Lisa is a huge fan of Red Light Therapy and runs a Hyperbaric and Red Light Therapy clinic. If you are wanting to get the best products try Flexbeam: A wearable Red Light Device https://recharge.health/product/flexbeam-aff/?ref=A9svb6YLz79r38   Or Try Vielights' advanced Photobiomodulation Devices Vielight brain photobiomodulation devices combine electrical engineering and neuroscience. To find out more about photobiomodulation, current studies underway and already completed and for the devices mentioned in this video go to www.vielight.com and use code “tamati” to get 10% off     Enjoyed This Podcast? If you did, subscribe and share it with your friends! If you enjoyed tuning in, then leave us a review and share this with your family and friends. Have any questions? You can contact my team through email (support@lisatamati.com) or find me on Facebook, Twitter, Instagram and YouTube. For more episode updates, visit my website. You may also tune in on Apple Podcasts.  To pushing the limits, Lisa and team

Le curcuma : un aliment magique ? Un des produits choisi dans mon prochain livre sur les stars de l'alimentation ou des compléments alimentaires, c'est le curcuma. C'est une épice jaune vif originaire d'Asie du Sud-Est, connue pour sa saveur et sa couleur uniques. Ces dernières années, il a fait l'objet de nombreuses études scientifiques et a gagné en popularité pour ses prétendues propriétés médicinales antioxydantes, anti-inflammatoires, anti-infectieuses, anticancéreuses... Mais le curcuma est-il vraiment un remède miracle ou s'agit-il simplement d'une arnaque ? Dans ce live, nous allons explorer la science derrière le curcuma et découvrir la vérité. N'oubliez pas de relayer notre opération #stopobesite et merci de votre soutien et de faire votre analyse minceur gratuite avec Jean-Michel Cohen Vous souhaitez mieux manger, maigrir, rééquilibrer votre alimentation, apprendre à toujours faire les bons choix alimentaires ?Faites votre analyse minceur gratuite avec Jean-Michel Cohen Découvrez l'ActiBox Minceur Dr Cohen, la boîte d'assistance à l'amaigrissement conçue pour éviter tous les “parasites” du régime Abonnez-vous ici à la chaîne Savoir Maigrir sur Youtube Découvrez la chaîne Youtube de Jean-Michel Cohen Consultez les Lettres d'Information du Dr Jean-Michel Cohen Visitez la page Facebook Savoir Maigrir avec Jean-Michel Cohen Suivez les stories de Jean-Michel Cohen sur Instagram

In dieser Folge spreche ich mit Marc über Kurkuma. naja hauptsächlich - wir sprechen auch über vieles mehr. Marc ist Gründer von Curcama - eine kleine BIO–Manufaktur im Herzen von Wien, die ausschließlich mit 100% natürlichen BIO-Lebensmitteln arbeitet. Seine absolute Leidenschaft ist der Kurkuma. Natürlich will ich alles von ihm wissen: Ist Kurkuma wirklich so gesund? Für was nutze ich Kurkuma? Was sind Mythen und was stimmt. Das Prinzip von Mythen und Wahrheiten nutzten wir nicht nur auf den Kurkuma an, sondern auf einiges mehr. Wir sprechen über Apfelessig, Wimhof, Routinen und Superfoods. Es wird nachhaltig und bewusst. ************** Curcama: https://www.curcama.at Michael Puntigam: Gesundheit durch die Kraft der Nahrung: TCM, Nachhaltigkeit und bewusste Ernährung ************** Code Everydays: annelina10 https://www.everydays.de ************** Blog: https://annelinawaller.com Podcast: https://open.spotify.com/show/58BYIK2fH9d9ho2Oqx3wLI?si=jDBCCLiwTTyEupCln0oL6 Instagram: https://www.instagram.com/annelinawaller/ Pinterest: https://nl.pinterest.com/annelinawaller/ Buch: https://www.amazon.de/Ein-Bauch-voll-Glück-Vegan/dp/395575197X/ref=sr12?dib=eyJ2IjoiMSJ9.Gep441sWaefowdgZxBWNZEoKVJ3R32lhtCar7FCNIDMU9477JIDLpWUBeEAzOohU1gXmBAIMaBnLGw5cegufpw.pWXkctiTaD-70bCENCnxwsYtAdISKUgb4WV94ReXPB0&dibtag=se&qid=1710483684&refinements=p27%3AAnnelina+Waller&s=books&sr=1-2

Revue scientifique : violette odorante pour les bouffées de chaleur, le plantain pour les escarres, le curcuma comme alternative aux IPPs. Abonnez-vous à la lettre d'information gratuite ! C'est ici : ➜ www.altheaprovence.com/podcast-lettreinfo ---------------------------- La transcription du podcast : ➜ https://www.altheaprovence.com/bdh6-violette-et-menopause-plantain-et-escarres-curcuma-et-ipps/

Au programme de cet épisode, le curcuma ! Une plante plus connue sous forme d'épice qui nous vient d'Asie du Sud Est et d'Inde. Elle est devenue la STAR de la phytothérapie, on la voit partout ! Le curcuma a de multiples pouvoirs : c'est un puissant antioxydant, il maintient également le foie en bonne santé et contribue à un bon confort digestif. Découvrez tous les bienfaits du curcuma dans cet épisode du podcast Arkopharma. Pour en savoir plus sur les produits Arkopharma, rendez-vous sur www.arkopharma.com.

Cyril Lignac partage ses astuces pour réaliser une recette originale d'œufs cocotte.

Today we reach the end of our apothecary shelves! This series started way back with episode 170 on Achillea & Acorus, and today in episode 227 we've finally come to Zingiber.Today's entire episode is all about ginger. (Yes, it deserves its own entire episode. If you don't already believe it, we will convince you!)We discuss Katja's evolving preference for fresh vs dried ginger in our tea blends at home, and some of the variations in activity between fresh vs dried ginger. We talk about quick topical applications of this wildly accessible herb, to relieve muscle aches, joint pains, and other musculoskeletal discomforts. Ryn takes time for an ode to candied ginger – yes, it's sugar, but there are plenty of reasons why it's excellent to have! You can easily make your own, too.Maybe you could put some chopped candied ginger into some ginger-chamomile cookies, eh?You can even grow your own ginger, if you're up for it!Finally, we mention some relatives of ginger, members of the Zingiberaceae: turmeric (Curcuma longa), galangal (Alpinia galanga), cardamom (Elettaria cardamomum), grains of paradise (Aframomum melegueta), korarima (Aframomum corrorima), “shampoo ginger lily / bitter ginger” (Zingiber zerumbet). These are all worth experimenting with and comparing to ginger – they have a lot in common, with some individual nuances. Watch out for “wild gingers” of the Asarum genus, though – those have risks of liver toxicity.Ginger's an herb we love so much, we probably mention it in every course we teach… but especially in the Digestive Health course! Learning to care for digestion is a critical skill for herbalists, and a place herbs can do so much good.Like all our offerings, this is a self-paced online video course, which comes with free access to twice-weekly live Q&A sessions, lifetime access to current & future course material, twice-weekly live Q&A sessions with us, open discussion threads integrated in each lesson, an active student community, study guides, quizzes & capstone assignments, and more!If you enjoyed the episode, it helps us a lot if you subscribe, rate, & review our podcast wherever you listen. This helps others find us more easily. Thank you!Our theme music is “Wings” by Nicolai Heidlas.Support the showYou can find all of our online herbalism courses at online.commonwealthherbs.com!

durée : 00:27:43 - Gingembre, curcuma et citronnelle

La curcuma, pianta erbacea perenne originaria dell'India, è un ingrediente tipico della cucina asiatica; la sua radice essicata e macinata dà origine a una polvere dorata e brillante. Molti sono i benefici che può apportare alla salute. Di questi ne ha parlato in un articolo di approfondimento la Dottoressa Elisabetta Macorsini di Humanitas Mater Domini.

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Professor Carsten Jahnke, one of the leading historians on the Hanse has kindly granted us an interview where we discuss how the Hanse network functioned and how the perception of the Hanse has changed dramatically over the last 200 years, a story that almost as interesting as the history of the Hanse itself.As listeners of the last season of the History of the Germans might have noticed, I have been relying heavily extensively on Carsten Jahnke's work. many of the episodes discussing the economic structure and the way money transfers worked in the network are based on his research. So if you liked those episodes, you will certanly enjoy this interview. Listen in!And here are some links to research Carsten recommends for those of you who want to follow up further:Christian Manger,Behind the scenes: Urban secretaries as managers of legal and diplomatic conflicts in the Baltic region, c.1470–1540: https://www.tandfonline.com/doi/full/10.1080/03044181.2022.2098528Carsten Jahnke, Von Mandeln, Narde, Curcuma und Kümmel. Herkunft, Handel und Verbrauch von „exotischen“ Gewürzen und Lebensmitteln im nördlichen Europa, in: Die Ausgrabungen im Lübecker Gründungsviertel II. Archäoparasitologie, Handelsgeschichte, Paläopathologie und Anthropologie, ed. by Dirk Rieger, Lübeck 2022, s. 131-164Carsten Jahnke, Hansische Kaufleute und deren Religiosität ausserhalb ihrer Heimat, i: Zapiski Historyczne, Tom LXXXIV, Rok 2019, Zeszyt 1, s. 7-41.There is also a lecture Cartsen gave at the German Historical institute in London on teh perception history:https://www.ghil.ac.uk/publications/podcasts/the-hanseatic-league-as-a-national-projectThe music for the show is Flute Sonata in E-flat major, H.545 by Carl Phillip Emmanuel Bach (or some claim it as BWV 1031 Johann Sebastian Bach) performed and arranged by Michel Rondeau under Common Creative Licence 3.0.As always:Homepage with maps, photos, transcripts and blog: www.historyofthegermans.comFacebook: @HOTGPod Twitter: @germanshistoryInstagram: history_of_the_germansReddit: u/historyofthegermansPatreon: https://www.patreon.com/Historyofthegermans

Professor Carsten Jahnke, one of the leading historians on the Hanse has kindly granted us an interview where we discuss how the Hanse network functioned and how the perception of the Hanse has changed dramatically over the last 200 years, a story that almost as interesting as the history of the Hanse itself.As listeners of the last season of the History of the Germans might have noticed, I have been relying heavily extensively on Carsten Jahnke's work. many of the episodes discussing the economic structure and the way money transfers worked in the network are based on his research. So if you liked those episodes, you will certanly enjoy this interview. Listen in!And here are some links to research Carsten recommends for those of you who want to follow up further:Christian Manger, Behind the scenes: Urban secretaries as managers of legal and diplomatic conflicts in the Baltic region, c.1470–1540: https://www.tandfonline.com/doi/full/10.1080/03044181.2022.2098528Carsten Jahnke, Von Mandeln, Narde, Curcuma und Kümmel. Herkunft, Handel und Verbrauch von „exotischen“ Gewürzen und Lebensmitteln im nördlichen Europa, in: Die Ausgrabungen im Lübecker Gründungsviertel II. Archäoparasitologie, Handelsgeschichte, Paläopathologie und Anthropologie, ed. by Dirk Rieger, Lübeck 2022, s. 131-164Carsten Jahnke, Hansische Kaufleute und deren Religiosität ausserhalb ihrer Heimat, i: Zapiski Historyczne, Tom LXXXIV, Rok 2019, Zeszyt 1, s. 7-41.There is also a lecture Cartsen gave at the German Historical institute in London on teh perception history: https://www.ghil.ac.uk/publications/podcasts/the-hanseatic-league-as-a-national-projectThe music for the show is Flute Sonata in E-flat major, H.545 by Carl Phillip Emmanuel Bach (or some claim it as BWV 1031 Johann Sebastian Bach) performed and arranged by Michel Rondeau under Common Creative Licence 3.0.As always:Homepage with maps, photos, transcripts and blog: www.historyofthegermans.comFacebook: @HOTGPod Twitter: @germanshistoryInstagram: history_of_the_germansReddit: u/historyofthegermansPatreon: https://www.patreon.com/Historyofthegermans

Turmeric: It can kill youTurmeric is from the root of a flowering plant (Curcuma longa of the ginger family Zingiberaceae), known for being anti-inflammatory. Because of its anti-inflammatory nature, turmeric is one of the most common supplements I am asked about during my TikTok live sessions. This is because people like a "natural" anti-inflammatory supplement rather than over-the-counter medications.SupplementsSupplements are excluded from "black box warnings." Those warnings you see in the package inserts in pharmaceuticals. This article is meant to provide references for those interested in doing more research about Tumeric to realize it is not benign.Turmeric has many potential applications for cancer, brain injury, and many other diseases. The key is knowing what dose of turmeric is toxic, what dose is effective, and what dose is ineffective. We also need to know how to mitigate potential dangers.Contrast with AspirinAspirin is a known anti-inflammatory agent with many uses. Since aspirin is regulated, we know the dose effect of aspirin. If you have a headache, the 81 mg dose of aspirin will not relieve your headache. But the 325 mg dose will decrease headache. And you know that taking two hundred tablets of aspirin is a toxic dose.A single aspirin can cause a bleeding ulcer, which may lead to death. Some people are allergic to aspirin, and an allergic reaction can lead to death.What we don't know is the effective dose of Turmeric or the lethal dose of it in that supplement bottle. But we know that turmeric, curcumin can lead to liver injury and death.Turmeric and Liver InjuryToxicity is always in the dose. High curcumin levels, the active ingredient in turmeric, have caused liver damage (Ref 1-13). To quote from one of the references:Liver injury due to turmeric appears to be increasing in the United States, perhaps reflecting usage patterns or increased combination with black pepper. (2)Turmeric and CookingThere is no danger in using turmeric as a spice in cooking. First, because your intestines do not absorb turmeric well. Unlike a supplement, which has high doses of curcumin. In addition, supplements also have black pepper, which increases absorption. Since turmeric has a mild anti-inflammatory component, this might have limited benefits as part of a healthy diet. Tumeric belongs in the cabinet, not in a capsule.TEXT FROM THE PODCASTYou probably have some turmeric in your herb and spice drawer.You've probably heard that Turmeric's active ingredient Curcumin has anti-inflammatory properties and has been used for centuries as an “ancient” medicine.That yellow powder comes from the root of the Curcuma longa plant, a member of the ginger family.Turmeric has a warm, bitter taste, and I use it in Paella, curry, and add it to salads, rice, or other starches like pearl barley.But what you haven't heard is that too much Turmeric can kill you.Today we will make sense of the madness surrounding Turmeric. From its promise as an anti-cancer agent to its toxicity, and who should avoid it for daily use.FORK UI'm Dr. Terry Simpson, and THIS is FORK UFork UniversityWhere we make sense of the madnessBust a few myths!And teach you a little bit about food as medicine.InflammationInflammation is a complex biochemical, physiological, and even pathological process. Inflammation is the basis of our immune system, and acute inflammation allows us to rid our bodies of cancer, viruses, bacteria, yeasts, mold, and parasites. Without the inflammatory process, we would end up being a pile of goo in twenty-four hours – dead as dead can be. Inflammation allows us

Petrone Group azienda con sede a Fisciano (SA), con progetti di espansione e trasferimento a Ravello, in costiera amalfitana, detiene il brevetto di Innovative Enrichment Milk (IEM) un dispositivo di recentissime invenzione (2017) firmato da Vincenzo Petrone, che punta a rivoluzionare l'industria casearia raggiungendo contemporaneamente importanti obiettivi di sostenibilità.

Cyril Lignac partage sa recette de poisson au lait de coco et au curcuma.

Le SIBO ? Sûrement un terme dont vous n'avez jamais entendu parler ! C'est normal puisqu'il est beaucoup moins connu que son cousin le “syndrome du côlon irritable”.Néanmoins, SIBO et côlon irritable ont de nombreux symptômes qui se confondent. À tel point que l'on peut parfois penser diagnostiquer un côlon irritable et passer à côté d'un SIBO / SIFO.Pour avoir les idées plus claires sur le sujet, écoutez bien cet épisode dans lequel je vous explique ce qu'est le SIBO et comment le dépister. Je vous donne aussi mes 3 règles d'or alimentaires pour sortir de l'état de dysbiose et je partage avec vous mes plantes préférées pour soulager ce trouble digestif. Bonne écoute !

Accidentes que dan risa en un fin de semana de waterpark.¡Ponte los audífonos y escucha el podcast del Free Guey Show en Uforia, Apple Podcast o Spotify o en tu plataforma favorita!

A la cúrcuma se le adjudican grandes beneficios. Pero, ¿qué es verdad y que es fantasía? Descubre los últimos avances en materia de este suplemento. Y recuerda, solo ciencia, nada de dramas. -Dr. Mau Fuentes: Efficacy and safety of Curcuma domestica extracts compared with ibuprofen in patients with knee osteoarthritis: a multicenter study https://pubmed.ncbi.nlm.nih.gov/24672232/ Chronic Supplementation of Curcumin Enhances the Efficacy of Antidepressants in Major Depressive Disorder: A Randomized, Double-Blind, Placebo-Controlled Pilot Study. https://pubmed.ncbi.nlm.nih.gov/26066335/ Effects of Curcuminoids on Systemic Inflammation and Quality of Life in Patients with Colorectal Cancer Undergoing Chemotherapy: A Randomized Controlled Trial. https://pubmed.ncbi.nlm.nih.gov/34981467/ The Effects of Curcumin on Diabetes Mellitus: A Systematic Review https://pubmed.ncbi.nlm.nih.gov/34012421/

Salut mes femmes en santé ! Ici Alie Bragz pour l'épisode E027 (et non 26 comme j'ai mentionné dans l'épisode, une petite erreur, le temps passe trop vite!) de l'ABC de la Perte de Poids et aujourd'hui, on va élaborer sur le « C » de connaissances. Je veux qu'à la suite de cette émission tu en connaisses davantage sur l'inflammation autant au niveau du cerveau qu'au niveau du corps. Si tu es une femme qui a fait le yoyo avec son poids, on va voir aujourd'hui que ce n'est pas juste une question hormonale. En effet, je ne sais pas si tu es le genre de femme qui a commencé à prendre soin d'elle-même. Tu te lèves plus tôt le matin afin d'aller au gym et même prendre maintenant le temps de déjeuner afin de ne pas négliger son apport calorique. Tu as même refusé deux fois du dessert cette semaine, mais malgré tous tes efforts, tu n'as vu aucun résultat sur la balance. Maudit que ça peut être frustrant, je le sais ! Tu dois cependant comprendre que parfois, pour certaines femmes, c'est un peu plus compliqué que cela une perte de poids et ça, ça peut être en raison d'une inflammation dans ton corps. Ça tombe bien, c'est justement le sujet de cet épisode !   Mot de la fin sur ton inflammation fait monter la balance En souhaitant que tu aies apprécié l'épisode du jour et si ce n'est pas déjà fait, je t'invite à t'abonner à mon nouveau compte Instagram: https://www.instagram.com/coachaliebragz/ . Je te partage du contenu exclusif ainsi que des capsules pour t'aider à perdre du gras et du poids. Au menu pour le prochain épisode, soit le E028, il sera question de la santé sexuelle de la femme. Je voulais élaborer là-dessus, car cela est relié à ta perte de poids ainsi qu'à ta santé en général. Abonne-toi au podcast pour ne rien manquer de tout ça. Tu recevras une notification lorsque l'épisode sera en ligne ! Les liens mentionnés dans l'épisode: Code promo de 15% sur les suppléments: Alie Oméga-3 :  https://www.designsforhealth.ca/u/aliebragz/products/omegavail-smoothie-mango-peach-cn/ Curcuma evail :  https://www.designsforhealth.ca/u/aliebragz/products/curcum-evail-cn/ Neuromag magnésium :  https://www.designsforhealth.ca/u/aliebragz/products/neuromag-capsules-cn/ Carnitine synergie :  https://www.designsforhealth.ca/u/aliebragz/products/carnitine-synergy-cn/ Pour me rejoindre :  Mon compte Instagram : https://www.instagram.com/coachaliebragz/ La gestion du stress | E003 : https://podcast.ausha.co/l-abc-de-la-perte-de-poids-avec-alie-bragz/la-gestion-du-stress-e003  Comment lire une étiquette afin de perdre du gras | E024 : https://podcast.ausha.co/l-abc-de-la-perte-de-poids-avec-alie-bragz/comment-lire-une-e-tiquette-afin-de-perdre-du-gras-e024  La communauté Facebook francophone #1 pour optimiser ton hygiène de vie afin d'atteindre ton plein potentiel ( + 9 000 membres) :  https://www.facebook.com/groups/thinkifit/  Page Facebook : https://facebook.com/aliebragz/  Profil LinkedIn : https://www.linkedin.com/in/aliebragz/  Compte Tik Tok : https://www.tiktok.com/@aliebragz Site web ThinkiFit : https://thinkifit.com/ Unique Jungle Gym : https://www.facebook.com/uniquejunglegym/ 

Curcuma, zenzero, melograno, papaya fermentata, avocado, alga spirulina... Sono moltissimi gli alimenti, le spezie e gli estratti vegetali pubblicizzati come potenti antiage. Ma cosa aspettaresi da queste sostanze? www.starbene.it

Cette épice est un puissant antioxydant qui, associée aux lentilles, apporte des saveurs estivales corsées. Pour réaliser une salade de lentilles au curcuma pour 4 personnes, vous aurez besoin de 100g de lentilles, 200g de fond d'artichaut, 1 filet de truite fumé, 3 cuillère à soupe de vinaigre balsamique, 3 cuillère à soupe de moutarde à l'ancienne, 2 cuillères à soupe de curcuma, 6 cuillères à soupe d'huile d'olive, 3 cuillères à soupe de persil haché, du sel et du poivre.

Découvrez tous les bienfaits du Curcuma sur votre cheval avec Laura, vétérinaire équin.

https://phoenixvitamins.com/product/natural-anti-inflammatory-support/ https://phoenixvitamins.com/product/the-best-slim-cleanse/ https://phoenixvitamins.com/product/complete-joint-support/ 619-871-1855 High potency turmeric supplement enhanced with bioperine. Our turmeric formula has 1500mg of turmeric curcumin with 95% standardized curcuminoids per serving (high potency) and 10mg of bioperine (black pepper, curcumin with black pepper) aiding in enhanced absorption and bio-availability. All natural, non-GMO, no fillers, binders, or preservatives. Our professional grade turmeric with bioperine (curcumin with bioperine) is a natural turmeric powder; turmeric powder has higher absorption compared to common turmeric teas, and this curcumin is also hypo-allergenic and free of soy, gluten, milk, egg, wheat, GMOs, peanuts, sweeteners, shellfish, and sugar. Formulated by leading biochemists: Our professional formula is made in the USA: Phoenix Nutritionals Natural Anti-inflammatory Support is manufactured in the USA following strict GMP guidelines. Our turmeric curcumin supplement's potency is enhanced with patented bioperine (10mg per serving), a type of black pepper extract shown to increase absorption and bioavailability in turmeric supplements. Curcumin is the major bioactive component found in the roots of turmeric (Curcuma longa), a plant belonging to the ginger family. Turmeric has been used as a coloring and flavoring agent in South Asian cuisines for centuries, and it has also been recommended by traditional Ayurvedic herbalists for thousands of years. Curcumin has been extensively researched by modern scientists for its various biological activities. Super high potency Turmeric Supplement with enhanced piperine. With our high absorption compared to common turmeric teas with much stronger results. This type of natural supplement is perfect for a women or man who wants to enjoy the benefits of turmeric curcumin supplements with maximum results. Stop sitting on the side lines of life and attack the day with enhanced absorption by the body by taking a super formula.

Basare sind die Supermärkte des Orients. Hier pulsiert das Leben. Sie sind Treffpunkt, Einkaufsmeile und Restaurant zugleich. Wer hier einkauft, findet alles: Obst und Fleisch ebenso wie Kleidung, Putzmittel oder CDs. Es riecht nach Koriander und Curcuma, Knoblauch und orientalischen Gewürzen. Berühmt sind die Basare von Taschkent und Samarkand, in Usbekistan, im Herzen von Zentralasien. Hier verlief die alte Seidenstraße. Aber auch kleinere Städte wie Termiz oder Bishkek, Kirgistan, haben ihre Basare. Zentralasien, zwischen dem Kaspischen Meer, Russland und China gelegen, mit den fünf unabhängigen Staaten Kasachstan, Kirgistan, Tadschikistan, Turkmenistan und Usbekistan hat rund 65 Millionen Einwohner. Die Hälfte von ihnen wohnt im Herzen der Region, in Usbekistan. Dort leuchten die türkisfarbigen Kuppeln berühmter alter Bauten über vielspurigen Straßen und modernen Shopping Centern. Trotz der vielen Neuerungen in Usbekistan in den letzten Jahren, hat Usbekistan seine Traditionen erhalten - und die Basare! Sie sind viel besucht und beliebt, von jung und alt, bei jedem Wetter und zu allen Jahreszeiten. Birgit Wetzel war für uns unterwegs auf den Basaren in Zentralasien.

In seguito ad alcune segnalazioni di effetti avversi pervenute all'Istituto Superiore di Sanità, la curcuma è passata rapidamente da ingrediente di tendenza negli integratori alimentari a ingrediente percepito dall'opinione pubblica addirittura come pericoloso [Testo: Marta Faggian, Giovanni Tafuro, Giulia Galizia, Alessandra Semenzato. Voce: Giovanni Tafuro]

►Check out our fanlink.to/Y0UTUBE for your audiovisual experience◄ Roxānitā presents a delicious Curcuma Blossom, a gin based cocktail with curcuma and orange juice! About Roxānitā: After a time of deep inner self-discovery, I became increasingly aware of the ancient knowledge stored within my consciousness. Tapping into this Source of infinite ability and energy and so channelling it through the being as embodiment was the most empowering experience that has ever happened to me. Rippling frequencies of contagious light and transmuting cosmical sounds in vibrations to ignite the oneness manifestation. This is my mission, my purpose - all is divinely aligned with my soul's path of ascension. I am Roxānitā Cheers The bartenders Roxānitā @iamroxanita www.facebook.com/iamroxanita www.instagram.com/i.am.roxanita Schirmchendrink @schirmchendrink www.facebook.com/schirmchendrink www.instagram.com/schirmchendrink

AGAIN…Happy Black History Month, We're continuing the Tropical Roots Series with… TURMERIC! Another plant in the ginger family - Zingiberaceae family. We're connecting the sister herbs in this family, and we're letting you know some interesting facts about turmeric. We're also going to give y'all a recipe from Lakshmi Nair on socials… so look out for that! Have you cleaned your house yet, this weekend? Well if not, this is the soundtrack to get it done! Enjoy bbs! Topics Discussed: turmeric (Curcuma longa) as an anti-inflammatory (most of the references will be coming from this one book)Yost, Debora, and Aggarwal, Bharat B.. Healing Spices: How to Use 50 Everyday and Exotic Spices to Boost Health and Beat Disease. United States, Sterling, 2011. mullien (Verbascum thapsus) linden (Tilia americana) Black Panther Wakanda Forever *slight spoilers* hibiscus (Hibiscus sabdariffa) cardamom (Elettaria cardamomum) Beverly Grant Lakshmi Nair Hatha Yoga Golden Milk Turmeric Latte galangal (Alpinia officinarum) ________________________ Follow us on social: @pettyherbalist @bonesbugsandbotany Join the Patreon Community to fund this amazing POD: https://www.patreon.com/pettyherbalist Rate us to show your support! Thank You! #StayReady #BePetty --- Send in a voice message: https://anchor.fm/pettyherbalist/message Support this podcast: https://anchor.fm/pettyherbalist/support

“Curcumin seems to preserve, and even repair, damaged tendons. In this systematic review, we focus more especially on the benefits of curcumin.” #curcumin #tendon #tendinopathy Córdova A, Drobnic F, Noriega-González D, Caballero-García A, Roche E, Alvarez-Mon M. Is Curcumine Useful in the Treatment and Prevention of the Tendinopathy and Myotendinous Junction Injury? A Scoping Review. Nutrients. 2023; 15(2):384. https://doi.org/10.3390/nu15020384 Curcumin, tendon, tendinopathy, collagen, type 1, inflammation, substance p, Curcuma longa, Myotendinous Junction Injury, prevention, repair, regeneration, leukocytes, Curcumine, crosslinking, antialgic Curcumin, Tendinopathy and Myotendinous Junction Injury Episode 1120 JAN 2023 #curcumin #tendon #tendinopathy #myotendinous #repair #regeneration --- Support this podcast: https://podcasters.spotify.com/pod/show/ralph-turchiano/support

“Curcumin seems to preserve, and even repair, damaged tendons. In this systematic review, we focus more especially on the benefits of curcumin.” #curcumin #tendon #tendinopathy Córdova A, Drobnic F, Noriega-González D, Caballero-García A, Roche E, Alvarez-Mon M. Is Curcumine Useful in the Treatment and Prevention of the Tendinopathy and Myotendinous Junction Injury? A Scoping Review. Nutrients. 2023; 15(2):384. https://doi.org/10.3390/nu15020384 Curcumin, tendon, tendinopathy, collagen, type 1, inflammation, substance p, Curcuma longa, Myotendinous Junction Injury, prevention, repair, regeneration, leukocytes, Curcumine, crosslinking, antialgic Curcumin, Tendinopathy and Myotendinous Junction Injury Episode 1120 JAN 2023 #curcumin #tendon #tendinopathy #myotendinous #repair #regeneration --- Support this podcast: https://podcasters.spotify.com/pod/show/ralph-turchiano/support

Videos: Brought to you by… Pfizer! FORMER PFIZER VP, DR. MIKE YEADON – EVERYTHING WE HAVE BEEN TOLD ABOUT COVID-19 WAS A LIE Fauci didn't want autopsies done on Covid victims. I wonder why? Dr. Peter McCullough SLAMS Pfizer board member over censorship and propaganda | Redacted News Study explores effects of dietary choline deficiency on neurologic and system-wide health Arizona State University, January 16, 2023 Choline, an essential nutrient produced in small amounts in the liver and found in foods including eggs, broccoli, beans, meat and poultry, is a vital ingredient for human health. A new study explores how a deficiency of dietary choline adversely affects the body and may be a missing piece in the puzzle of Alzheimer's disease. It's estimated that more than 90% of Americans are not meeting the recommended daily intake of choline. The current research, conducted in mice, suggests that dietary choline deficiency can have profound negative effects on the heart, liver and other organs. Lack of adequate choline is also linked with profound changes in the brain associated with Alzheimer's disease. These include pathologies implicated in the development of two classic hallmarks of the illness: amyloid plaques, which aggregate in the intercellular spaces between neurons; and tau tangles, which condense within the bodies of neurons. The new research, led by scientists at Arizona State University and published in Aging Cell, describes pathologies in normal mice deprived of dietary choline and in choline-deficient transgenic mice, the latter of which already exhibit symptoms associated with the disease. In both cases, dietary choline deficiency results in liver damage, enlargement of the heart and neurologic alterations in the AD mice, typically accompanying Alzheimer's disease and including increased levels of plaque-forming amyloid-beta protein and disease-linked alterations in tau protein. Further, the study illustrates that choline deficiency in mice causes significant weight gain, alterations in glucose metabolism (which are tied to conditions such as diabetes), and deficits in motor skills. In the case of humans, “it's a twofold problem,” according to Ramon Velazquez, senior author of the study and assistant professor with the ASU-Banner Neurodegenerative Disease Research Center. “First, people don't reach the adequate daily intake of choline established by the Institute of Medicine in 1998. And secondly, there is vast literature showing that the recommended daily intake amounts are not optimal for brain-related functions.” The research highlights a constellation of physical and neurological changes linked to choline deficiency. Sufficient choline in the diet reduces levels of the amino acid homocysteine, which has been recognized as a neurotoxin contributing to neurodegeneration, and is important for mediating functions such as learning and memory through the production of acetylcholine. The growing awareness of choline's importance should encourage all adults to ensure proper choline intake. This is particularly true for those on plant-based diets, which may be low in naturally occurring choline, given that many foods high in choline are eggs, meats, and poultry. Plant-based, choline-rich foods, including soybeans, Brussels sprouts and certain nuts can help boost choline in these cases. Moreover, inexpensive, over-the-counter choline supplements are encouraged to promote overall health and guard the brain from the effects of neurodegeneration. The new study examines mice at 3-12 months, or early to late adulthood (roughly equivalent to 20-60 years of age for humans). In the case of both normal and transgenic mice displaying symptoms of Alzheimer's, those exposed to a choline-deficient diet exhibited weight gain and adverse effects to their metabolism. Damage to the liver was observed through tissue analysis, as was enlargement of the heart. Elevated soluble, oligomeric and insoluble amyloid-beta protein were detected, as well as modifications to tau protein characteristic of those leading to neurofibrillary tangles in the brain. Further, choline-deficient mice performed poorly in a test of motor skills, when compared with mice receiving adequate choline in their diet. These adverse effects were heightened in the transgenic mice. Translating these findings to humans, this implies that people who are predisposed to Alzheimer's disease or in the throes of the illness should ensure they are getting enough choline.”Our work provides further support that dietary choline should be consumed on a daily basis given the need throughout the body,” Velazquez says. (NEXT) Melanoma: Vitamin D supplements linked to reduced skin cancer risk University of Eastern Finland & Kuopio University, January 15, 2023 A new study finds that the regular use of vitamin D is associated with lower rates of melanoma skin cancer. The cross-sectional study was a collaboration between the University of Eastern Finland and Kuopio University Hospital. The research involved 498 Finnish adults determined by dermatologists to be at high risk of skin cancer, such as melanoma, as well as squamous cell carcinoma and basal cell carcinoma. According to researchers, people who took vitamin D regularly were less likely to have had melanoma in the past or currently and were deemed by dermatologists to be less likely to develop melanoma in the future. Study participants ranged in age from 21 to 79 years old, including 253 males and 245 females. Participants were divided into three groups based on their intake of vitamin D supplements: non-use, occasional use, or regular use. The researchers were also interested in finding out whether regular use of vitamin D supplements corresponded to higher blood levels of vitamin D, known as serum calcidiol or 25-hydroxy-vitamin D3. This is the “storage form” of vitamin D in the body. Some research has linked low serum calcidiol with increased cancer risk, while other research has suggested otherwise. Nonetheless, it is a measure often used to determine a person's vitamin D levels. After testing serum calcidiol levels in 260 participants, researchers found that regular vitamin D supplementation corresponded with the highest levels of serum calcidiol and non-supplementation with the lowest levels. “Human skin itself expresses [the enzyme] CYP27A1 that produces calcidiol from vitamin D, and CYP27B1 that produces biologically very active calcitriol from calcidiol,” Dr. Harvima explained, noting that enzyme expression determines the level of vitamin D and its metabolites in the body. (NEXT) New research furthers case for exercise promoting youthfulness University of Arkansas, January 17, 2023 A recent paper published in the Journal of Physiology deepened the case for the youthfulness-promoting effects of exercise on aging organisms, building on previous work done with lab mice nearing the end of their natural lifespan that had access to a weighted exercise wheel. For this paper, the researchers compared aging mice that had access to a weighted exercise wheel with mice that had undergone epigenetic reprogramming via the expression of Yamanaka factors. The Yamanaka factors are four protein transcription factors (identified as Oct3/4, Sox2, Klf4 and c-Myc, often abbreviated to OKSM) that can revert highly specified cells (such as a skin cell) back to a stem cell, which is a younger and more adaptable state. The Nobel Prize in Physiology or Medicine was awarded to Dr. Shinya Yamanaka for this discovery in 2012. In the correct dosages, inducing the Yamanaka factors throughout the body in rodents can ameliorate the hallmarks of aging by mimicking the adaptability that is common to more youthful cells. Of the four factors, Myc is induced by exercising skeletal muscle. Myc may serve as a naturally induced reprogramming stimulus in muscle, making it a useful point of comparison between cells that have been reprogrammed via over expression of the Yamanaka factors and cells that have been reprogrammed through exercise—”reprogramming” in the latter case reflecting how an environmental stimulus can alter the accessibility and expression of genes. Ultimately, the team determined that exercise promotes a molecular profile consistent with epigenetic partial programming. That is to say, exercise can mimic aspects of the molecular profile of muscles that have been exposed to Yamanaka factors (thus displaying molecular characteristics of more youthful cells). This beneficial effect of exercise may in part be attributed to the specific actions of Myc in muscle. Murach sees their research as further validation of exercise as a polypill. “Exercise is the most powerful drug we have,” he says, and should be considered a health-enhancing—and potentially life-extending—treatment along with medications and a healthy diet. (NEXT) Exploiting the synergy of nutraceuticals for cancer prevention and treatment Research suggests that free radicals (ROS) generated upon mixing two nutraceuticals—resveratrol and copper—can help ameliorate various diseases by inactivating cell-free chromatin particles Tata Memorial Centre (India), January 16, 2023 Chromatin comprises a complex mixture of DNA and proteins that forms the structural basis of chromosomes in the cellular nuclei. When cells die, they release cell-free chromatin particles or “cfChPs” into the circulatory system. In 1996, evidence for tumour-derived DNA circulating in the blood of cancer patients was first reported. This evidence caught the interest Dr. Indraneel Mittra, who is now Professor Emeritus and the Dr. Ernest Borges Chair in Translational Research at Tata Memorial Centre in Mumbai, India. His tryst with research on genetic material in cancer metastases began, and after 15 years of research he has presented various papers, developing a body of evidence that indicates the critical role of cfChPs in orchestrating development of not only cancer, but various other diseases. Emerging evidence indicates that cfChPs play an essential role in ageing, sepsis, cancer development, and chemotherapy-related toxicity. With respect to the latter, Prof. Mittra explains, “Chemo-toxicity is not primarily caused by chemotherapeutic drugs, but rather by cfChPs that are released from the first cells that die after chemotherapy. The released cfChPs set in motion a cascading effect, increasingly damaging the DNA of healthy host cells, and triggering inflammatory processes in a vicious cycle that perpetuates and prolongs the toxicity of chemotherapy.” Recently, a team from Tata Memorial Centre have demonstrated the therapeutic benefits of a pro-oxidant mixture of resveratrol and copper, R-Cu, in patients undergoing chemotherapy for advanced gastric cancer. Combining R with Cu (R-Cu) leads to the generation of free oxygen radicals which can inactivate the offending cfChPs. In this context, the research team launched a single-arm phase II clinical trial to study the synergistic effects of R-Cu administration on cfChPs inactivation in patients with advanced gastric cancer. The primary objective was to determine whether R-Cu, via cfChPs' inactivation, was successful in reducing the grade ≥ 3 toxicity seen with docetaxel-based chemotherapies. To this end, the researchers monitored the likely changes in the toxicities of chemotherapeutic treatments using a grading system that provides a framework for the assessment of unwanted physiological effects. The results were promising—although R-Cu did not reduce haematological toxicities, it significantly reduced the incidence of non-haematological toxicities comprising hand-foot syndrome, diarrhoea, and vomiting. Moreover, R-Cu reduced docetaxel exposure compared to the control arm without affecting efficacy in terms of overall survival. (NEXT) Deep meditation may alter gut microbes for better health Shanghai Jiao Tong University School of Medicine (China), January 16, 2023 Regular deep meditation, practiced for several years, may help to regulate the gut microbiome and potentially lower the risks of physical and mental ill health, finds a small comparative study published in the open access journal General Psychiatry. The gut microbes found in a group of Tibetan Buddhist monks differed substantially from those of their secular neighbors, and have been linked to a lower risk of anxiety, depression, and cardiovascular disease. Research shows that the gut microbiome can affect mood and behavior through the gut–brain axis. This includes the body's immune response, hormonal signaling, stress response and the vagus nerve—the main component of the parasympathetic nervous system, which oversees an array of crucial bodily functions. The significance of the group and specimen design is that these deep-thinking Tibetan monks can serve as representatives of some deeper meditations. Although the number of samples is small, they are rare because of their geographical location. The researchers analyzed the stool and blood samples of 37 Tibetan Buddhist monks from three temples and 19 secular residents in the neighboring areas. None of the participants had used agents that can alter the volume and diversity of gut microbes: antibiotics; probiotics; prebiotics; or antifungal drugs in the preceding 3 months. Sample analysis revealed significant differences in the diversity and volume of microbes between the monks and their neighbors.”Collectively, several bacteria enriched in the meditation group [have been] associated with the alleviation of mental illness, suggesting that meditation can influence certain bacteria that may have a role in mental health,” write the researchers. These include Prevotella, Bacteroidetes, Megamonas and Faecalibacterium species, the previously published research suggests. Finally, blood sample analysis showed that levels of agents associated with a heightened risk of cardiovascular disease, including total cholesterol and apolipoprotein B, were significantly lower in the monks than in their secular neighbors by their functional analysis with the gut microbes. (NEXT) Curcumin/Boswellia shows promise in chronic kidney disease Baylor University, January 14, 2023. The Journal of Complementary and Integrative Medicine reports the finding of researchers at Baylor University of a reduction in a marker of inflammation among chronic kidney disease patients given a combination of Curcuma longa (curcumin) and Boswellia serrata. The study included sixteen individuals receiving standard care for chronic kidney disease who were not undergoing dialysis. Participants were randomized to receive capsules containing curcumin from turmeric extract plus Boswellia serrata, or a placebo for eight weeks. Blood samples collected before and after treatment were analyzed for plasma interleukin-6 (IL-6), tumor necrosis factor alpha (markers of inflammation), and the endogenous antioxidant enzyme glutathione peroxidase, as well as serum C-reactive protein (CRP, another marker of inflammation.) Blood test results from the beginning of the study revealed increased inflammation and reduced glutathione peroxide levels. At the study's conclusion, participants who received curcumin and Boswellia serrata experienced a reduction in interleukin-6 in comparison with pretreatment values, indicating decreased inflammation, while IL-6 values rose among those who received a placebo. In their discussion of the findings, the authors remark that curcumin and Boswellia serrata have been separately shown to lower interleukin-6 via inhibition of the nuclear factor kappa beta and mitogen activated protein kinase (MAPK) signaling pathways.

Episodio 12 de “La voce della nutrizione – Pink Positive Edition. Stili di vita sani al centro del percorso di cura”. Un podcast di Smartfood Istituto Europeo di Oncologia, promosso dalla partnership Fondazione IEO-MONZINO e Daiichi Sankyo, pensato per fornire informazioni chiare e affidabili, in tema alimentazione e salute. L'alimentazione gioca sicuramente un ruolo chiave nello sviluppo delle più comuni patologie, tra cui i tumori, ma non esistono prove scientifiche solide che dimostrino che un singolo alimento, nutriente o composto chimico, che magari si assume in quantità minime nel quotidiano, sia in grado di inibire o promuovere l'insorgenza o la ricorrenza del cancro. In questo episodio sfatiamo tutti i miti legati a curcuma, zenzero, poliammine e glicoalcaloidi.

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Il dottor Franco Berrino in un nuovo articolo per il Corriere della Sera spiega come il DNA sia influenzato dall'ambiente in cui viviamo, dal cibo che mangiamo e dalle nostre abitudini di vita. Secondo il medico, il nostro stile di vita interagisce con i nostri geni e influenza lo stato di salute. In particolare, fa sapere Berrino: «La curcuma, il resveratrolo dell’uva, i composti solforati dei cavoli, ad esempio, attivano l’enzima DNA metiltransferasi, che metila il DNA, mentre i polifenoli del tè verde e quelli della soia, il licopene dei pomodori e i composti solforati dell’aglio ne bloccano l’azione. Analogamente i composti dei cavoli, dell’uva e dell’aglio attivano l’acetilazione degli istoni e altri composti la disattivano». Inoltre, «la nostra attività fisica influenza la metilazione del DNA e persino la nostra vita spirituale, la meditazione, agisce sull’acetilazione degli istoni», mentre «una dieta troppo ricca di glucosio inibisce la produzione di microRNA16, che riduce la proliferazione cellulare (mir16 è disattivato in molti tumori)», scrive ancora Berrino.

Dee and Carol talk about hidden lilies, some All-America Selection vegetables, monarchs, and more in this week's episode.Link to our Substack newsletter with more information about this week's episode. Be sure and subscribe to get the newsletter directly in your email inbox! Hidden Lilies, Curcuma alismatifolia  Dee's Instagram pics of these lilies - here and here Newly announced All-America Selections winners for 2023Pepper cayenne Wildcat F1 Watermelon Rubyfirm F1Also, shout out for the 2022 All-America tomato, Tomato Purple Zebra F1                                        (National Winner) and Begonia Viking Explorer Rose on Green F1   (And on Carol's Instagram) On the bookshelf:   Green Kitchen: Quick & Slow: Joyful Vegetarian Recipes for Quick Weeknight Fixes and Slow Weekend Meals by  David Frenkiel  (Author), Luise Vindahl  (Author) (Amazon Link)   Check out the authors' blog, Green Kitchen StoriesUpdates on Monarchs     Daily briefing: Monarch butterflies are an endangered species andMonarchs | U.S. Fish & Wildlife ServiceThe Language of Butterflies by Wendy Williams (Amazon Link)More on Gladys Taber - Friend of Gladys TaberAffiliate link to Botanical Interest Seeds. (If you buy something from them after using this link, we earn a small commission at no cost to you. This helps us continue to bring this podcast to you ad-free!)  Book links are also affiliate links.Email us at TheGardenangelists@gmail.com  For more info on Carol and her books, visit her website.  Visit her blog May Dreams Gardens.For more info on Dee and her book, visit her website.  Visit her blog Red Dirt Ramblings.Don't forget to sign up for our newsletters, via our websites! 

*Cet épisode a été réalisé grâce au soutien d'Arcadie, je les remercie de soutenir Basilic* Cette semaine, Jeane reçoit Mégane Forestier et Julie Raymond, toutes deux salariées de l'entreprise Arcadie. L'histoire d'Arcadie est une histoire fabuleuse qui mérite pleinement d'être racontée au micro de Basilic. Cette aventure débute à la fin des années 1970, alors que l'agriculture biologique est encore marginale. Dominique et Bernard Kimmel, deux étudiants (faculté de psychologie pour elle, sciences politiques et faculté de mathématiques pour lui), laissent tomber leur avenir tout tracé dans une société dont ils ne partagent plus les valeurs. Ils se lancent alors dans l'une des premières productions françaises de plantes médicinales et aromatiques issues de culture biologique. En 1990, Dominique et Bernard créent Arcadie, Cook et l'Herbier de France. C'est le début d'une très belle aventure. 32 ans plus tard, l'entreprise familiale existe toujours et ce sont les enfants du couple fondateur qui ont repris le flambeau. Dans cet épisode, Mégane et Julie nous partagent la belle histoire d'Arcadie. Au fil de cette conversation, vous en apprendrez davantage sur les épices et leur utilisation. Il est certain qu'après avoir écouté cet épisode, vous n'utiliserez plus vos gousses de vanille de la même façon ! Liens utiles pour suivre l'épisode : Arcadie : https://www.arcadie.fr/ Instagram : s'abonner Soutenir Basilic : instagram.com/basilicpodcast/ basilicpodcast.com Production : Jeane Clesse Musique : @Klein Graphisme : Mahaut Clément & Coralie Chauvin Mix : Jeane Clesse Si cet épisode vous a plu, n'hésitez pas à laisser plein d'étoiles et un commentaire sur la plateforme Apple Podcasts et surtout à vous abonner grâce à votre application de podcasts préférée ! Cela m'aide énormément à faire découvrir Basilic à de nouveaux auditeurs et de nouvelles auditrices.

You've likely heard about the many health benefits of turmeric (Curcuma longa L.) and its compound curcumin. But did you know that it can be difficult to “unlock” the nutrients in turmeric so your body can actually take full advantage of them? Tune in to today's episode to unlock the magic of turmeric!   Turmeric and Black Pepper: The Best Way to Take Turmeric? You've likely heard about the many health benefits of turmeric (Curcuma longa L.) and its compound curcumin. But did you know that it can be difficult to “unlock” the nutrients in turmeric so your body can actually take full advantage of them? One popular way to make the compounds in turmeric more bioavailable (absorbable and usable to the body) is to pair it with another popular cooking spice: black pepper [1]. But what if there was a better way than combining turmeric and black pepper? A way to boost turmeric's bioavailability, allowing it to more safely and effectively support the natural healing process?   The Healing Power of Turmeric Turmeric is a staple remedy from the traditional medicine systems of the Far East that has gained widespread popularity throughout the West in recent years as a “super” spice. Turmeric's many health-supportive properties are attributed to curcumin, a key component of turmeric that's associated with longevity. Curcumin is documented in the scientific literature as offering powerful support for the cardiovascular, neurological, metabolic, immune, and cellular systems. It's also the part of turmeric that gives this root spice its rich, golden yellow color. But the truth of the matter is that humans have a difficult time getting all the health benefits from turmeric when consuming the spice all by itself. Research shows that only a very small portion of it is assimilated into the body when eaten in isolation. This is why many natural health experts suggest consuming turmeric along with black pepper (Piper nigrum). Black pepper contains a unique “bio-enhancer” compound known as piperine that significantly boosts turmeric's bioavailability – by as much as 2,000 percent, in fact. This is the reason why many turmeric and curcumin supplement products on the market today contain either black pepper or piperine.   The Problem: Black Pepper Isn't Good for Everyone This pairing approach of turmeric and black pepper comes with limitations, however, as too much black pepper can actually be detrimental to health – especially in people with gastrointestinal issues.Research published in the American Journal of Gastroenterology found that consuming black pepper in excess can damage the mucosal lining of the gut, potentially causing bleeding or other injuries. Consuming high amounts of black pepper, this same study found, is akin to taking the painkiller drug aspirin [2]. In other words, aspirin represents a similar threat to the gut lining in terms of its tendency to cause serious erosions and ulcers in the intestinal tract [3]. This isn't to say that black pepper is inherently dangerous, and there's no need to toss out the pepper shaker just yet. After all, the amounts of black pepper required to induce such harm are far greater than what the average person consumes in their food on a daily basis. There's also evidence to show that taking curcumin along with just piperine, black pepper's primary alkaloid, is typically safe and causes “no adverse effects [4].” Even so, there's always the possibility that someone might react negatively to this combination – especially when taking very high doses of turmeric or curcumin for therapeutic purposes. For this reason, science set out to determine whether or not it was possible to retain turmeric's full bioavailability without the need for black pepper, piperine, or any other additive. And the good news is, it is possible.   Fermentation Increases the Power of Turmeric BETTER Than Black Pepper As it turns out, by fermenting turmeric its active constituents can be drawn out and made more potent in a way similar to, and potentially even greater than, black pepper. Here's another reason why fermented turmeric may be superior to turmeric and black pepper. Besides possibly upsetting a person's digestive system, black pepper is known to interfere with a process known as glucuronidation that's necessary for eliminating toxins from the body [5]. Put simply, too much black pepper can cause a buildup of xenoestrogens (harmful chemicals found in plastic and other everyday products) and other toxins that would otherwise be quickly eliminated from the body [6]. With simple fermentation, however, there's little-to-no risk of these types of complications. That's because there's nothing like black pepper getting in the way to block the body's important detoxification pathways. It's rather like eating fresh turmeric, which still contains all of the volatile (essential) oils that help to deliver the herb's active compounds throughout the body. Fermentation may even go a step beyond this by further optimizing turmeric's absorption potential. Research conducted on rat models found that fermented turmeric is, indeed, the best form of turmeric because it contains the most antioxidant power. Compared to ground turmeric in powder and probiotic forms, fermented turmeric led to substantially higher plasma antioxidant concentrations in test subjects [7]. In terms of how it affects the liver, fermented turmeric was shown in a paper out of South Korea to be powerfully hepatoprotective, meaning it shields the liver from damage. Not only that, but fermented turmeric was also shown to help improve the liver's functional detoxification potential [8] – as opposed to black pepper-potentiated turmeric that can inhibit natural detoxification. Fermented turmeric also contains more curcumin (the beneficial compound) than unfermented turmeric, by volume. In addition to improving both its antioxidant and antimicrobial capacity, fermenting turmeric draws out an impressive 11% more curcumin compared to what's found in raw turmeric. Fermentation also makes turmeric 3.1 times more effective at scavenging oxidizing free radicals from the body [9]. Another area where fermented turmeric has a leg up on both unfermented turmeric and turmeric combined with black pepper is in the area of inflammation. Research published by The Korean Society for Applied Microbiology and Biotechnology found that fermented turmeric is a powerful anti-inflammatory, possessing the ability to inhibit pro-inflammatory cytokines much more effectively than any other known form of turmeric. Fermented turmeric was further shown in this same study to protect against acute anaphylactic, or allergic, reactions [10]. From an antimicrobial perspective, fermented turmeric shows incredible potential against a wide variety of pathogenic bacteria, including drug-resistant “superbugs.” Research out of the Middle East found that fermented turmeric provides broad-spectrum protection against harmful bacteria such as Escherichia coli (E. coli), Streptococcus agalactiae, Staphylococcus aureus (Staph), Entreococcus faecalis, Methicillin-Resistant Staphylococcus aureus (MRSA), Klebsiella pneumonia, and Pseudomonas aeruginosae [11]. Research out of China found that fermented curcumin can be a powerful weapon against high cholesterol, also known as hyperlipidemia. While unfermented curcumin showed minimal-to-no benefits during the evaluation, its fermented counterpart significantly reduced serum lipid levels in test models [12].   Fermented Turmeric Increased Fat Loss in Animal Test Subjects Fermented turmeric also shows promise in fighting another undesirable form of fat: the obesity kind. Research out of South Korea found that consumption of fermented turmeric can alter the expression of certain genes involved with lipid accumulation, effectively preventing them from communicating to the body that it's time to pack on extra pounds [13]. Related research published a year later, also out of South Korea, reiterated these findings while building upon them. Obese rats fed a high-fat diet not only didn't gain more weight when also consuming fermented turmeric, but they further lost weight as a result of consuming the herb as part of their daily eating routines [14].   Preventing Impairment of Learning and Memory Research has shown there are brain benefits associated with fermented turmeric as well. Among the findings fleshed out in a paper published in the journal BMC Complementary and Alternative Medicine was evidence suggesting that fermented turmeric has the potential to mitigate memory impairment while supporting optimized learning and memory ability in mice [15]. While more research needs to be done, the evidence so far seems clear… fermentation is the key to “unlocking” the incredible healing potential of turmeric, while avoiding the potential side effects of combining turmeric and black pepper.   Resources: Turmeric 3D by Organixx ParActin®: A Potent Form of Andrographis Paniculata for Pain Support & More – Episode 87 The BIG 3 Anti-Inflammatories – Episode 88 [1] Recent developments in delivery, bioavailability, absorption and metabolism of curcumin: the golden pigment from golden spice. [2] Effect of red pepper and black pepper on the stomach. [3] The Effects of Aspirin and Acetaminophen on the Stomach in Healthy Volunteers [4] Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. [5] Turmeric, Hold the Black Pepper Please! [6] Glucuronidation [7] Study on enhanced absorption of phenolic compounds of Lactobacillus‐fermented turmeric (Curcuma longa Linn.) beverages in rats [8] The effectiveness of fermented turmeric powder in subjects with elevated alanine transaminase levels: a randomised controlled study [9] Antioxidant and Antimicrobial Effects of Fermented Tumeric (Curcuma longa L.) [10] Antiinflammatory and Antiallergic Activity of Fermented Turmeric by Lactobacillus [11] Influence of solid state fermentation by Trichoderma spp. on solubility, phenolic content, antioxidant, and antimicrobial activities of commercial turmeric. [12] Study of the property of lipids reducing of curcumin on hyperlipidemia mice after fermented by Monascus purureus. [13] Evaluation of the Anti-obesity Activity of Platycodon grandiflorum Root and Curcuma longa Root Fermented with Aspergillus oryzae [14] Anti-obesity effect of extract from fermented Curcuma longa L. through regulation of adipogenesis and lipolysis pathway in high-fat diet-induced obese rats. [15] The protective effect of fermented Curcuma longa L. on memory dysfunction in oxidative stress-induced C6 gliomal cells, proinflammatory-activated BV2 microglial cells, and scopolamine-induced amnesia model in mice [16] Is Turmeric Good for Your Heart? Here's What the Science Shows [17] 10 Surprising Ways Turmeric Benefits a Woman's Health

You've likely heard about the many health benefits of turmeric (Curcuma longa L.) and its compound curcumin. But did you know that it can be difficult to “unlock” the nutrients in turmeric so your body can actually take full advantage of them? Tune in to today's episode to unlock the magic of turmeric!   Turmeric and Black Pepper: The Best Way to Take Turmeric? You've likely heard about the many health benefits of turmeric (Curcuma longa L.) and its compound curcumin. But did you know that it can be difficult to “unlock” the nutrients in turmeric so your body can actually take full advantage of them? One popular way to make the compounds in turmeric more bioavailable (absorbable and usable to the body) is to pair it with another popular cooking spice: black pepper [1]. But what if there was a better way than combining turmeric and black pepper? A way to boost turmeric's bioavailability, allowing it to more safely and effectively support the natural healing process?   The Healing Power of Turmeric Turmeric is a staple remedy from the traditional medicine systems of the Far East that has gained widespread popularity throughout the West in recent years as a “super” spice. Turmeric's many health-supportive properties are attributed to curcumin, a key component of turmeric that's associated with longevity. Curcumin is documented in the scientific literature as offering powerful support for the cardiovascular, neurological, metabolic, immune, and cellular systems. It's also the part of turmeric that gives this root spice its rich, golden yellow color. But the truth of the matter is that humans have a difficult time getting all the health benefits from turmeric when consuming the spice all by itself. Research shows that only a very small portion of it is assimilated into the body when eaten in isolation. This is why many natural health experts suggest consuming turmeric along with black pepper (Piper nigrum). Black pepper contains a unique “bio-enhancer” compound known as piperine that significantly boosts turmeric's bioavailability – by as much as 2,000 percent, in fact. This is the reason why many turmeric and curcumin supplement products on the market today contain either black pepper or piperine.   The Problem: Black Pepper Isn't Good for Everyone This pairing approach of turmeric and black pepper comes with limitations, however, as too much black pepper can actually be detrimental to health – especially in people with gastrointestinal issues.Research published in the American Journal of Gastroenterology found that consuming black pepper in excess can damage the mucosal lining of the gut, potentially causing bleeding or other injuries. Consuming high amounts of black pepper, this same study found, is akin to taking the painkiller drug aspirin [2]. In other words, aspirin represents a similar threat to the gut lining in terms of its tendency to cause serious erosions and ulcers in the intestinal tract [3]. This isn't to say that black pepper is inherently dangerous, and there's no need to toss out the pepper shaker just yet. After all, the amounts of black pepper required to induce such harm are far greater than what the average person consumes in their food on a daily basis. There's also evidence to show that taking curcumin along with just piperine, black pepper's primary alkaloid, is typically safe and causes “no adverse effects [4].” Even so, there's always the possibility that someone might react negatively to this combination – especially when taking very high doses of turmeric or curcumin for therapeutic purposes. For this reason, science set out to determine whether or not it was possible to retain turmeric's full bioavailability without the need for black pepper, piperine, or any other additive. And the good news is, it is possible.   Fermentation Increases the Power of Turmeric BETTER Than Black Pepper As it turns out, by fermenting turmeric its active constituents can be drawn out and made more potent in a way similar to, and potentially even greater than, black pepper. Here's another reason why fermented turmeric may be superior to turmeric and black pepper. Besides possibly upsetting a person's digestive system, black pepper is known to interfere with a process known as glucuronidation that's necessary for eliminating toxins from the body [5]. Put simply, too much black pepper can cause a buildup of xenoestrogens (harmful chemicals found in plastic and other everyday products) and other toxins that would otherwise be quickly eliminated from the body [6]. With simple fermentation, however, there's little-to-no risk of these types of complications. That's because there's nothing like black pepper getting in the way to block the body's important detoxification pathways. It's rather like eating fresh turmeric, which still contains all of the volatile (essential) oils that help to deliver the herb's active compounds throughout the body. Fermentation may even go a step beyond this by further optimizing turmeric's absorption potential. Research conducted on rat models found that fermented turmeric is, indeed, the best form of turmeric because it contains the most antioxidant power. Compared to ground turmeric in powder and probiotic forms, fermented turmeric led to substantially higher plasma antioxidant concentrations in test subjects [7]. In terms of how it affects the liver, fermented turmeric was shown in a paper out of South Korea to be powerfully hepatoprotective, meaning it shields the liver from damage. Not only that, but fermented turmeric was also shown to help improve the liver's functional detoxification potential [8] – as opposed to black pepper-potentiated turmeric that can inhibit natural detoxification. Fermented turmeric also contains more curcumin (the beneficial compound) than unfermented turmeric, by volume. In addition to improving both its antioxidant and antimicrobial capacity, fermenting turmeric draws out an impressive 11% more curcumin compared to what's found in raw turmeric. Fermentation also makes turmeric 3.1 times more effective at scavenging oxidizing free radicals from the body [9]. Another area where fermented turmeric has a leg up on both unfermented turmeric and turmeric combined with black pepper is in the area of inflammation. Research published by The Korean Society for Applied Microbiology and Biotechnology found that fermented turmeric is a powerful anti-inflammatory, possessing the ability to inhibit pro-inflammatory cytokines much more effectively than any other known form of turmeric. Fermented turmeric was further shown in this same study to protect against acute anaphylactic, or allergic, reactions [10]. From an antimicrobial perspective, fermented turmeric shows incredible potential against a wide variety of pathogenic bacteria, including drug-resistant “superbugs.” Research out of the Middle East found that fermented turmeric provides broad-spectrum protection against harmful bacteria such as Escherichia coli (E. coli), Streptococcus agalactiae, Staphylococcus aureus (Staph), Entreococcus faecalis, Methicillin-Resistant Staphylococcus aureus (MRSA), Klebsiella pneumonia, and Pseudomonas aeruginosae [11]. Research out of China found that fermented curcumin can be a powerful weapon against high cholesterol, also known as hyperlipidemia. While unfermented curcumin showed minimal-to-no benefits during the evaluation, its fermented counterpart significantly reduced serum lipid levels in test models [12].   Fermented Turmeric Increased Fat Loss in Animal Test Subjects Fermented turmeric also shows promise in fighting another undesirable form of fat: the obesity kind. Research out of South Korea found that consumption of fermented turmeric can alter the expression of certain genes involved with lipid accumulation, effectively preventing them from communicating to the body that it's time to pack on extra pounds [13]. Related research published a year later, also out of South Korea, reiterated these findings while building upon them. Obese rats fed a high-fat diet not only didn't gain more weight when also consuming fermented turmeric, but they further lost weight as a result of consuming the herb as part of their daily eating routines [14].   Preventing Impairment of Learning and Memory Research has shown there are brain benefits associated with fermented turmeric as well. Among the findings fleshed out in a paper published in the journal BMC Complementary and Alternative Medicine was evidence suggesting that fermented turmeric has the potential to mitigate memory impairment while supporting optimized learning and memory ability in mice [15]. While more research needs to be done, the evidence so far seems clear… fermentation is the key to “unlocking” the incredible healing potential of turmeric, while avoiding the potential side effects of combining turmeric and black pepper.   Resources: Turmeric 3D by Organixx ParActin®: A Potent Form of Andrographis Paniculata for Pain Support & More – Episode 87 The BIG 3 Anti-Inflammatories – Episode 88 [1] Recent developments in delivery, bioavailability, absorption and metabolism of curcumin: the golden pigment from golden spice. [2] Effect of red pepper and black pepper on the stomach. [3] The Effects of Aspirin and Acetaminophen on the Stomach in Healthy Volunteers [4] Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. [5] Turmeric, Hold the Black Pepper Please! [6] Glucuronidation [7] Study on enhanced absorption of phenolic compounds of Lactobacillus‐fermented turmeric (Curcuma longa Linn.) beverages in rats [8] The effectiveness of fermented turmeric powder in subjects with elevated alanine transaminase levels: a randomised controlled study [9] Antioxidant and Antimicrobial Effects of Fermented Tumeric (Curcuma longa L.) [10] Antiinflammatory and Antiallergic Activity of Fermented Turmeric by Lactobacillus [11] Influence of solid state fermentation by Trichoderma spp. on solubility, phenolic content, antioxidant, and antimicrobial activities of commercial turmeric. [12] Study of the property of lipids reducing of curcumin on hyperlipidemia mice after fermented by Monascus purureus. [13] Evaluation of the Anti-obesity Activity of Platycodon grandiflorum Root and Curcuma longa Root Fermented with Aspergillus oryzae [14] Anti-obesity effect of extract from fermented Curcuma longa L. through regulation of adipogenesis and lipolysis pathway in high-fat diet-induced obese rats. [15] The protective effect of fermented Curcuma longa L. on memory dysfunction in oxidative stress-induced C6 gliomal cells, proinflammatory-activated BV2 microglial cells, and scopolamine-induced amnesia model in mice [16] Is Turmeric Good for Your Heart? Here's What the Science Shows [17] 10 Surprising Ways Turmeric Benefits a Woman's Health

You've likely heard about the many health benefits of turmeric (Curcuma longa L.) and its compound curcumin. But did you know that it can be difficult to “unlock” the nutrients in turmeric so your body can actually take full advantage of them? Tune in to today's episode to unlock the magic of turmeric!   Turmeric and Black Pepper: The Best Way to Take Turmeric? You've likely heard about the many health benefits of turmeric (Curcuma longa L.) and its compound curcumin. But did you know that it can be difficult to “unlock” the nutrients in turmeric so your body can actually take full advantage of them? One popular way to make the compounds in turmeric more bioavailable (absorbable and usable to the body) is to pair it with another popular cooking spice: black pepper [1]. But what if there was a better way than combining turmeric and black pepper? A way to boost turmeric's bioavailability, allowing it to more safely and effectively support the natural healing process?   The Healing Power of Turmeric Turmeric is a staple remedy from the traditional medicine systems of the Far East that has gained widespread popularity throughout the West in recent years as a “super” spice. Turmeric's many health-supportive properties are attributed to curcumin, a key component of turmeric that's associated with longevity. Curcumin is documented in the scientific literature as offering powerful support for the cardiovascular, neurological, metabolic, immune, and cellular systems. It's also the part of turmeric that gives this root spice its rich, golden yellow color. But the truth of the matter is that humans have a difficult time getting all the health benefits from turmeric when consuming the spice all by itself. Research shows that only a very small portion of it is assimilated into the body when eaten in isolation. This is why many natural health experts suggest consuming turmeric along with black pepper (Piper nigrum). Black pepper contains a unique “bio-enhancer” compound known as piperine that significantly boosts turmeric's bioavailability – by as much as 2,000 percent, in fact. This is the reason why many turmeric and curcumin supplement products on the market today contain either black pepper or piperine.   The Problem: Black Pepper Isn't Good for Everyone This pairing approach of turmeric and black pepper comes with limitations, however, as too much black pepper can actually be detrimental to health – especially in people with gastrointestinal issues.Research published in the American Journal of Gastroenterology found that consuming black pepper in excess can damage the mucosal lining of the gut, potentially causing bleeding or other injuries. Consuming high amounts of black pepper, this same study found, is akin to taking the painkiller drug aspirin [2]. In other words, aspirin represents a similar threat to the gut lining in terms of its tendency to cause serious erosions and ulcers in the intestinal tract [3]. This isn't to say that black pepper is inherently dangerous, and there's no need to toss out the pepper shaker just yet. After all, the amounts of black pepper required to induce such harm are far greater than what the average person consumes in their food on a daily basis. There's also evidence to show that taking curcumin along with just piperine, black pepper's primary alkaloid, is typically safe and causes “no adverse effects [4].” Even so, there's always the possibility that someone might react negatively to this combination – especially when taking very high doses of turmeric or curcumin for therapeutic purposes. For this reason, science set out to determine whether or not it was possible to retain turmeric's full bioavailability without the need for black pepper, piperine, or any other additive. And the good news is, it is possible.   Fermentation Increases the Power of Turmeric BETTER Than Black Pepper As it turns out, by fermenting turmeric its active constituents can be drawn out and made more potent in a way similar to, and potentially even greater than, black pepper. Here's another reason why fermented turmeric may be superior to turmeric and black pepper. Besides possibly upsetting a person's digestive system, black pepper is known to interfere with a process known as glucuronidation that's necessary for eliminating toxins from the body [5]. Put simply, too much black pepper can cause a buildup of xenoestrogens (harmful chemicals found in plastic and other everyday products) and other toxins that would otherwise be quickly eliminated from the body [6]. With simple fermentation, however, there's little-to-no risk of these types of complications. That's because there's nothing like black pepper getting in the way to block the body's important detoxification pathways. It's rather like eating fresh turmeric, which still contains all of the volatile (essential) oils that help to deliver the herb's active compounds throughout the body. Fermentation may even go a step beyond this by further optimizing turmeric's absorption potential. Research conducted on rat models found that fermented turmeric is, indeed, the best form of turmeric because it contains the most antioxidant power. Compared to ground turmeric in powder and probiotic forms, fermented turmeric led to substantially higher plasma antioxidant concentrations in test subjects [7]. In terms of how it affects the liver, fermented turmeric was shown in a paper out of South Korea to be powerfully hepatoprotective, meaning it shields the liver from damage. Not only that, but fermented turmeric was also shown to help improve the liver's functional detoxification potential [8] – as opposed to black pepper-potentiated turmeric that can inhibit natural detoxification. Fermented turmeric also contains more curcumin (the beneficial compound) than unfermented turmeric, by volume. In addition to improving both its antioxidant and antimicrobial capacity, fermenting turmeric draws out an impressive 11% more curcumin compared to what's found in raw turmeric. Fermentation also makes turmeric 3.1 times more effective at scavenging oxidizing free radicals from the body [9]. Another area where fermented turmeric has a leg up on both unfermented turmeric and turmeric combined with black pepper is in the area of inflammation. Research published by The Korean Society for Applied Microbiology and Biotechnology found that fermented turmeric is a powerful anti-inflammatory, possessing the ability to inhibit pro-inflammatory cytokines much more effectively than any other known form of turmeric. Fermented turmeric was further shown in this same study to protect against acute anaphylactic, or allergic, reactions [10]. From an antimicrobial perspective, fermented turmeric shows incredible potential against a wide variety of pathogenic bacteria, including drug-resistant “superbugs.” Research out of the Middle East found that fermented turmeric provides broad-spectrum protection against harmful bacteria such as Escherichia coli (E. coli), Streptococcus agalactiae, Staphylococcus aureus (Staph), Entreococcus faecalis, Methicillin-Resistant Staphylococcus aureus (MRSA), Klebsiella pneumonia, and Pseudomonas aeruginosae [11]. Research out of China found that fermented curcumin can be a powerful weapon against high cholesterol, also known as hyperlipidemia. While unfermented curcumin showed minimal-to-no benefits during the evaluation, its fermented counterpart significantly reduced serum lipid levels in test models [12].   Fermented Turmeric Increased Fat Loss in Animal Test Subjects Fermented turmeric also shows promise in fighting another undesirable form of fat: the obesity kind. Research out of South Korea found that consumption of fermented turmeric can alter the expression of certain genes involved with lipid accumulation, effectively preventing them from communicating to the body that it's time to pack on extra pounds [13]. Related research published a year later, also out of South Korea, reiterated these findings while building upon them. Obese rats fed a high-fat diet not only didn't gain more weight when also consuming fermented turmeric, but they further lost weight as a result of consuming the herb as part of their daily eating routines [14].   Preventing Impairment of Learning and Memory Research has shown there are brain benefits associated with fermented turmeric as well. Among the findings fleshed out in a paper published in the journal BMC Complementary and Alternative Medicine was evidence suggesting that fermented turmeric has the potential to mitigate memory impairment while supporting optimized learning and memory ability in mice [15]. While more research needs to be done, the evidence so far seems clear… fermentation is the key to “unlocking” the incredible healing potential of turmeric, while avoiding the potential side effects of combining turmeric and black pepper.   Resources: Turmeric 3D by Organixx ParActin®: A Potent Form of Andrographis Paniculata for Pain Support & More – Episode 87 The BIG 3 Anti-Inflammatories – Episode 88 [1] Recent developments in delivery, bioavailability, absorption and metabolism of curcumin: the golden pigment from golden spice. [2] Effect of red pepper and black pepper on the stomach. [3] The Effects of Aspirin and Acetaminophen on the Stomach in Healthy Volunteers [4] Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. [5] Turmeric, Hold the Black Pepper Please! [6] Glucuronidation [7] Study on enhanced absorption of phenolic compounds of Lactobacillus‐fermented turmeric (Curcuma longa Linn.) beverages in rats [8] The effectiveness of fermented turmeric powder in subjects with elevated alanine transaminase levels: a randomised controlled study [9] Antioxidant and Antimicrobial Effects of Fermented Tumeric (Curcuma longa L.) [10] Antiinflammatory and Antiallergic Activity of Fermented Turmeric by Lactobacillus [11] Influence of solid state fermentation by Trichoderma spp. on solubility, phenolic content, antioxidant, and antimicrobial activities of commercial turmeric. [12] Study of the property of lipids reducing of curcumin on hyperlipidemia mice after fermented by Monascus purureus. [13] Evaluation of the Anti-obesity Activity of Platycodon grandiflorum Root and Curcuma longa Root Fermented with Aspergillus oryzae [14] Anti-obesity effect of extract from fermented Curcuma longa L. through regulation of adipogenesis and lipolysis pathway in high-fat diet-induced obese rats. [15] The protective effect of fermented Curcuma longa L. on memory dysfunction in oxidative stress-induced C6 gliomal cells, proinflammatory-activated BV2 microglial cells, and scopolamine-induced amnesia model in mice [16] Is Turmeric Good for Your Heart? Here's What the Science Shows [17] 10 Surprising Ways Turmeric Benefits a Woman's Health

You've likely heard about the many health benefits of turmeric (Curcuma longa L.) and its compound curcumin. But did you know that it can be difficult to “unlock” the nutrients in turmeric so your body can actually take full advantage of them? Tune in to today's episode to unlock the magic of turmeric!   Turmeric and Black Pepper: The Best Way to Take Turmeric? You've likely heard about the many health benefits of turmeric (Curcuma longa L.) and its compound curcumin. But did you know that it can be difficult to “unlock” the nutrients in turmeric so your body can actually take full advantage of them? One popular way to make the compounds in turmeric more bioavailable (absorbable and usable to the body) is to pair it with another popular cooking spice: black pepper [1]. But what if there was a better way than combining turmeric and black pepper? A way to boost turmeric's bioavailability, allowing it to more safely and effectively support the natural healing process?   The Healing Power of Turmeric Turmeric is a staple remedy from the traditional medicine systems of the Far East that has gained widespread popularity throughout the West in recent years as a “super” spice. Turmeric's many health-supportive properties are attributed to curcumin, a key component of turmeric that's associated with longevity. Curcumin is documented in the scientific literature as offering powerful support for the cardiovascular, neurological, metabolic, immune, and cellular systems. It's also the part of turmeric that gives this root spice its rich, golden yellow color. But the truth of the matter is that humans have a difficult time getting all the health benefits from turmeric when consuming the spice all by itself. Research shows that only a very small portion of it is assimilated into the body when eaten in isolation. This is why many natural health experts suggest consuming turmeric along with black pepper (Piper nigrum). Black pepper contains a unique “bio-enhancer” compound known as piperine that significantly boosts turmeric's bioavailability – by as much as 2,000 percent, in fact. This is the reason why many turmeric and curcumin supplement products on the market today contain either black pepper or piperine.   The Problem: Black Pepper Isn't Good for Everyone This pairing approach of turmeric and black pepper comes with limitations, however, as too much black pepper can actually be detrimental to health – especially in people with gastrointestinal issues.Research published in the American Journal of Gastroenterology found that consuming black pepper in excess can damage the mucosal lining of the gut, potentially causing bleeding or other injuries. Consuming high amounts of black pepper, this same study found, is akin to taking the painkiller drug aspirin [2]. In other words, aspirin represents a similar threat to the gut lining in terms of its tendency to cause serious erosions and ulcers in the intestinal tract [3]. This isn't to say that black pepper is inherently dangerous, and there's no need to toss out the pepper shaker just yet. After all, the amounts of black pepper required to induce such harm are far greater than what the average person consumes in their food on a daily basis. There's also evidence to show that taking curcumin along with just piperine, black pepper's primary alkaloid, is typically safe and causes “no adverse effects [4].” Even so, there's always the possibility that someone might react negatively to this combination – especially when taking very high doses of turmeric or curcumin for therapeutic purposes. For this reason, science set out to determine whether or not it was possible to retain turmeric's full bioavailability without the need for black pepper, piperine, or any other additive. And the good news is, it is possible.   Fermentation Increases the Power of Turmeric BETTER Than Black Pepper As it turns out, by fermenting turmeric its active constituents can be drawn out and made more potent in a way similar to, and potentially even greater than, black pepper. Here's another reason why fermented turmeric may be superior to turmeric and black pepper. Besides possibly upsetting a person's digestive system, black pepper is known to interfere with a process known as glucuronidation that's necessary for eliminating toxins from the body [5]. Put simply, too much black pepper can cause a buildup of xenoestrogens (harmful chemicals found in plastic and other everyday products) and other toxins that would otherwise be quickly eliminated from the body [6]. With simple fermentation, however, there's little-to-no risk of these types of complications. That's because there's nothing like black pepper getting in the way to block the body's important detoxification pathways. It's rather like eating fresh turmeric, which still contains all of the volatile (essential) oils that help to deliver the herb's active compounds throughout the body. Fermentation may even go a step beyond this by further optimizing turmeric's absorption potential. Research conducted on rat models found that fermented turmeric is, indeed, the best form of turmeric because it contains the most antioxidant power. Compared to ground turmeric in powder and probiotic forms, fermented turmeric led to substantially higher plasma antioxidant concentrations in test subjects [7]. In terms of how it affects the liver, fermented turmeric was shown in a paper out of South Korea to be powerfully hepatoprotective, meaning it shields the liver from damage. Not only that, but fermented turmeric was also shown to help improve the liver's functional detoxification potential [8] – as opposed to black pepper-potentiated turmeric that can inhibit natural detoxification. Fermented turmeric also contains more curcumin (the beneficial compound) than unfermented turmeric, by volume. In addition to improving both its antioxidant and antimicrobial capacity, fermenting turmeric draws out an impressive 11% more curcumin compared to what's found in raw turmeric. Fermentation also makes turmeric 3.1 times more effective at scavenging oxidizing free radicals from the body [9]. Another area where fermented turmeric has a leg up on both unfermented turmeric and turmeric combined with black pepper is in the area of inflammation. Research published by The Korean Society for Applied Microbiology and Biotechnology found that fermented turmeric is a powerful anti-inflammatory, possessing the ability to inhibit pro-inflammatory cytokines much more effectively than any other known form of turmeric. Fermented turmeric was further shown in this same study to protect against acute anaphylactic, or allergic, reactions [10]. From an antimicrobial perspective, fermented turmeric shows incredible potential against a wide variety of pathogenic bacteria, including drug-resistant “superbugs.” Research out of the Middle East found that fermented turmeric provides broad-spectrum protection against harmful bacteria such as Escherichia coli (E. coli), Streptococcus agalactiae, Staphylococcus aureus (Staph), Entreococcus faecalis, Methicillin-Resistant Staphylococcus aureus (MRSA), Klebsiella pneumonia, and Pseudomonas aeruginosae [11]. Research out of China found that fermented curcumin can be a powerful weapon against high cholesterol, also known as hyperlipidemia. While unfermented curcumin showed minimal-to-no benefits during the evaluation, its fermented counterpart significantly reduced serum lipid levels in test models [12].   Fermented Turmeric Increased Fat Loss in Animal Test Subjects Fermented turmeric also shows promise in fighting another undesirable form of fat: the obesity kind. Research out of South Korea found that consumption of fermented turmeric can alter the expression of certain genes involved with lipid accumulation, effectively preventing them from communicating to the body that it's time to pack on extra pounds [13]. Related research published a year later, also out of South Korea, reiterated these findings while building upon them. Obese rats fed a high-fat diet not only didn't gain more weight when also consuming fermented turmeric, but they further lost weight as a result of consuming the herb as part of their daily eating routines [14].   Preventing Impairment of Learning and Memory Research has shown there are brain benefits associated with fermented turmeric as well. Among the findings fleshed out in a paper published in the journal BMC Complementary and Alternative Medicine was evidence suggesting that fermented turmeric has the potential to mitigate memory impairment while supporting optimized learning and memory ability in mice [15]. While more research needs to be done, the evidence so far seems clear… fermentation is the key to “unlocking” the incredible healing potential of turmeric, while avoiding the potential side effects of combining turmeric and black pepper.   Resources: Turmeric 3D by Organixx ParActin®: A Potent Form of Andrographis Paniculata for Pain Support & More – Episode 87 The BIG 3 Anti-Inflammatories – Episode 88 [1] Recent developments in delivery, bioavailability, absorption and metabolism of curcumin: the golden pigment from golden spice. [2] Effect of red pepper and black pepper on the stomach. [3] The Effects of Aspirin and Acetaminophen on the Stomach in Healthy Volunteers [4] Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. [5] Turmeric, Hold the Black Pepper Please! [6] Glucuronidation [7] Study on enhanced absorption of phenolic compounds of Lactobacillus‐fermented turmeric (Curcuma longa Linn.) beverages in rats [8] The effectiveness of fermented turmeric powder in subjects with elevated alanine transaminase levels: a randomised controlled study [9] Antioxidant and Antimicrobial Effects of Fermented Tumeric (Curcuma longa L.) [10] Antiinflammatory and Antiallergic Activity of Fermented Turmeric by Lactobacillus [11] Influence of solid state fermentation by Trichoderma spp. on solubility, phenolic content, antioxidant, and antimicrobial activities of commercial turmeric. [12] Study of the property of lipids reducing of curcumin on hyperlipidemia mice after fermented by Monascus purureus. [13] Evaluation of the Anti-obesity Activity of Platycodon grandiflorum Root and Curcuma longa Root Fermented with Aspergillus oryzae [14] Anti-obesity effect of extract from fermented Curcuma longa L. through regulation of adipogenesis and lipolysis pathway in high-fat diet-induced obese rats. [15] The protective effect of fermented Curcuma longa L. on memory dysfunction in oxidative stress-induced C6 gliomal cells, proinflammatory-activated BV2 microglial cells, and scopolamine-induced amnesia model in mice [16] Is Turmeric Good for Your Heart? Here's What the Science Shows [17] 10 Surprising Ways Turmeric Benefits a Woman's Health

Rachel Musquiz is the CEO and founder of Curcuma. We met Rachel first while she still had a food truck here in Austin, she's full of knowledge, and we were excited that we got to interview her because she's about to leave Austin to go on a big road trip to explore the world. This conversation is full of great information, both scientific and just plain fun and we can't wait for you to listen.       Key Topics: Ayurvedic Practices The healing that goes back thousands of years Road Tripping Cooking Naturally Food is Medicine     WATCH THE VIDEO: https://youtu.be/jMEDcbYTWBI Connect with Rachel:   IG: @racheldrinksgold IG: @curcumakitchen www.curtcumakitchen.com   Episode Sponsored by MSW Nutrition Shop MSW Nutrition products: www.mswnutrition.com/?ref=hdyh use code HowDoYouHealth or HDYH for 15% OFF     CREDITS: Hosts - Baldomero Garza (@txmxyogi), Nurse Doza (@nursedoza) Guest -Rachel Musquiz [@racheldrinkgold] Podcast production - Baldomero Garza, HDYH Network [@howdoyouhealth] Intro song - Benjamin Banger

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FDA 批准靶向IL-23的单克隆抗体治疗银屑病Arthritis & Rheumatol 替格瑞洛治疗后骨关节炎风险的降低JAMA 生物力学鞋对膝骨关节炎患者膝关节疼痛的影响LANCET 非布司他与别嘌醇在痛风患者中的长期心血管安全性Nature子刊 抑制MEK使CD8+ T淋巴细胞重新编码为具有潜在抗肿瘤特性的记忆干细胞替达珠单抗（tildrakizumab）替达珠单抗（tildrakizumab）是人源化IgG1x单克隆抗体，靶向IL-23的p19亚基并阻断其与IL-23受体结合，抑制细胞因子与趋化因子释放。2018年3月FDA批准替达珠单抗用于治疗成人中重度斑块型银屑病。《reSURFACE1和reSURFACE2研究52周的综合分析：替达珠单抗治疗中重度银屑病52周的疗效的3期临床研究》Journal of European Academy of Dermatology & Venereology，2019年12月 (1) reSURFACE1和reSURFACE2研究的目的是观察替达珠单抗治疗中重度银屑病的疗效，前28周的结果已经证实了替达珠单抗的疗效，这篇文章报告了随访52周的结果，旨在评价治疗对患者皮肤科生活质量评分（DLQI）和银屑病面积和严重程度指数（PASI）评分的影响。两项研究中使用替达珠单抗100 mg或200 mg治疗的1156位患者，在第28周合并，然后根据第28周时的PASI评分改善程度分为5组：0-49分、50-74分、75-89分、90-99分和100分。第28周，替达珠单抗100 mg组和200 mg组根据PASI评分改善程度分组后的患者比例分别为8.3%、14.3%、23.8%、30.4%、23.1%，和4.0%、18.1%、19.6%、29.1%、29.3%。第28周疗效较差的、PASI改善50的患者中，持续使用相同剂量的替达珠单抗至第52周，PASI评分持续改善。两种剂量都观察到了类似的结果。28周时PASI改善较好的患者中，DLQI 0/1的比例较高，且维持或改善至52周。然而，并不是所有PASI改善100患者的DLQI都为0/1。结论：替达珠单抗疗效较差的患者可在第8周确定，疗效好、PASI评分改善≥90的患者通常可在第4周确定。第28周PASI改善水平与生活质量改善相关。骨关节炎骨关节炎（osteoarthritis，OA）是最常见的关节炎。发病机制中有很多重要的因素，包括生物力学因素、促炎因子和蛋白酶等。症状主要是特征性关节组织病理改变所引起的疼痛和关节功能改变，所有的OA患者都存在关节软骨、骨骼、滑膜和软组织的病理表现。《回顾性分析：与氯吡格雷相比，替格瑞洛治疗后骨关节炎风险的降低》Arthritis & Rheumatol，2020年11月 (2)细胞外腺苷具有抗炎作用，在动物模型中可预防和治疗骨关节炎。替格瑞洛和氯吡格雷都用于冠心病患者，但只有替格瑞洛增加了细胞外腺苷水平。这项研究是为了确定治疗替格瑞洛是否与降低骨关节炎风险有关。研究纳入替格瑞洛或氯吡格雷治疗≥90天的、没有关节炎病史的、21000例患者。平均治疗天数分别为287天和284天。两组患者的平均年龄均为64岁，73%为男性。多变量Cox回归分析估计，与氯吡格雷相比，替格瑞洛治疗后发生OA的危险比为0.71(95%可信区间0.64-0.79)(P < 0.001)。结论：在5年的随访中，与氯吡格雷治疗相比，替格瑞洛治疗降低了骨关节炎发病风险达29%，这可能与我们假设接受替格瑞洛的患者中OA的减少可能部分是由于细胞外腺苷水平的增加。《软骨缺失会导致骨关节炎疼痛吗？如果会，疼痛程度是多少?》Annals of Rheumatic Disease，2020年9月 (3)虽然骨关节炎的治疗重点是软骨保护，但目前尚不清楚预防软骨损失能在多大程度上减轻关节疼痛。研究量化了骨髓病变和滑膜炎后软骨损失、和膝关节疼痛恶化之间的关系，并检查了这些因素在多大程度上介导了这种关联。研究人员在基线、12个月和24个月时，对600例膝关节MRI定量、半定量测量骨关节炎的结构特征。定量的计算了内侧软骨厚度的变化、软骨损失情况、使用西安大略和麦克马斯特大学骨关节炎指数疼痛评分（WOMAC疼痛评分）评价疼痛程度。随访24个月，软骨厚度的减少与疼痛的轻微恶化显著相关。例如，两年内软骨厚度减少0.1mm，WOMAC疼痛增加0.32。软骨厚度的减少与疼痛的关系是通过滑膜炎的改变，而不是骨髓病变的改变。亚分析结果相似。结论：软骨厚度的减少只与少量的膝关节疼痛恶化有关，这种关联部分是由滑膜炎恶化引起的。通过软骨保护减少膝盖疼痛可能是难以实现的。骨关节炎的治疗膝关节骨性关节炎的治疗方法包括非药物治疗、药物治疗和手术，旨在缓解疼痛、改善关节功能以及改变骨关节炎进展的危险因素。尽管研究很多，但改变疾病病程的疗法效果欠佳。轻度骨性关节炎着重体重管理、镇痛、局部物理治疗；中重度骨性关节炎着重情绪疏导、镇痛、关节内注射类固醇、运动（建议水中锻炼，耐受性比地面锻炼好）和手术。《VITAL研究：补充维生素D和ω-3脂肪酸对老年慢性膝盖疼痛的影响》Arthritis & Rheumatol，2020年11月 (4)膝痛是成人骨关节炎的常见病因。该研究的目的是评价维生素D、ω-3脂肪酸治疗膝关节疼痛的效果。这项双盲、安慰剂对照的研究纳入25,871名参与者，按照2x2设计随机接受维生素D或ω-3脂肪酸，随机化之前，确定了一个膝盖疼痛的亚组，这组人群共1398人，平均年龄67岁，66%为女性，根据WOMAC评分评价关节疼痛程度。基线时，WOMAC疼痛评分平均值为37，平均随访时间为5.3年后，WOMAC疼痛评分在维生素D组、ω-3脂肪酸组和安慰剂组之间没有差异。随着时间的推移，补充维生素D和ω-3脂肪酸对WOMAC功能或僵硬评分也没有显著影响。结论：在慢性膝关节疼痛的大样本中，补充维生素D和ω-3脂肪酸持续5.3年并不能减轻膝关节疼痛、或改善关节功能或僵硬。《随机、双盲、安慰剂对照试验：白细胞介素-1β抑制对髋关节和膝关节置换术发生率的影响》Annals of Internal Medicine，2020年10月 (5) 研究的目的是确定IL-1抑制卡那单抗是否减少全髋关节或膝关节置换术的发生率。研究纳入1061例CANTOS研究的参与者，随机给予安慰剂、或卡那单抗50mg、150mg或300mg ip 三个月一次。平均随访3.7年，与安慰剂相比，卡那单抗组的关节置换的风险比分别为：50mg组为0.60，150mg组为0.53，300 mg组为0.60，均有统计学意义。将治疗组数据合并，关节置换发生率为0.31/100人年，安慰剂组为0.54例/100人年（风险比 0.58，P=0.001）。结论：该随机对照试验的探索性分析结果支持进一步研究IL-1抑制治疗大型关节骨性关节炎。《随机对照研究：膝关节骨性关节炎的物理治疗与糖皮质激素注射比较》New England Journal of Medicine，2020年4月 (6)物理治疗和关节内注射糖皮质激素已被证明对膝骨关节炎有临床疗效。该研究的目的是评价这两种疗法在缓解疼痛、改善身体功能方面的短期和长期效果。这项随机试验纳入单膝或双膝骨关节炎患者共156人，平均年龄56岁，随机接受糖皮质激素注射或接受物理治疗。基线WOMAC功能或僵硬度评分平均值，糖皮质激素注射组为108.8分，物理治疗组为107.1分；1年时的平均值分别为55.8分和37.0分。组间平均差异为18.8分，物理治疗更好。结论：与接受关节内糖皮质激素注射的膝关节骨性关节炎患者相比，接受物理治疗的膝关节骨性关节炎患者在1年的疼痛和功能残疾更少。《BIOTOK研究：生物力学鞋对膝骨关节炎患者膝关节疼痛的影响》JAMA，2020年5月 (7)研究的目的是评价个体化校准的生物力学鞋疗法是否可能改善有症状性的、膝骨关节炎患者的疼痛和功能。这项随机临床试验纳入症状性膝关节骨关节炎患者220名，平均年龄65.2岁，给予生物力学鞋治疗或安慰剂治疗，随访24周。随访24周时，生物力学鞋组的标准化WOMAC疼痛评分平均值从4.3提高到1.3，对照组鞋组从4.0提高到2.6（P 50岁的、膝关节骨关节炎和软骨下骨髓病变的223名成年患者，平均年龄62岁，女性52%。随机分组，分别在试验开始时和12个月的时候静脉滴注一次5mg唑来膦酸组或100ml生理盐水作为安慰剂。随访24个月，唑来膦酸组和安慰剂组的胫股软骨体积变化无显著差异（P = 0.50）。次要结果的组间差异均无统计学意义，包括膝关节疼痛评分、WOMAC骨关节炎指数、骨髓病灶大小变化。唑来膦酸的不良事件比安慰剂更常见。结论：症状性膝骨关节炎和骨髓病变患者中，每年注射唑来膦酸并没有显著减少软骨体积损失。这些发现不支持使用唑来膦酸治疗膝骨关节炎。《随机对照研究：姜黄提取物治疗膝关节骨关节炎症状及渗出性滑膜炎的疗效观察》Annals of Internal Medicine，2020年12月 (9)研究的目的是探讨姜黄提取物对症状性、膝关节骨性关节炎和膝关节渗出性滑膜炎的疗效。这项单中心研究招募了70名参与者，连续12周，每天2粒姜黄提取物或安慰剂。12周后，与安慰剂相比，姜黄提取物改善视觉模拟疼痛（VAS）评分的幅度为-9.1mm（P = 0.039），但没有改变渗出性滑膜炎体积（3.2mL）。姜黄提取物还可改善WOMAC膝关节疼痛评分（P = 0.006），但没有改善MRI腓骨外侧软骨T2松弛时间（−0.4 ms）。两组不良事件发生率相似（P = 0.16）结论：对于膝关节疼痛，姜黄提取物比安慰剂更有效，但不影响膝关节渗出性滑膜炎或软骨成分。需要更大样本量的多中心试验来评估这些发现的临床意义。痛风痛风是尿酸单钠结晶沉积病，其生化特点是细胞外液尿酸盐浓度达到饱和，血液中表现为高尿酸血症，即血尿酸盐浓度超过400μmol/L，该水平接近于尿酸盐的溶解度极限。痛风的临床表现包括：炎症性关节炎的反复发作、慢性关节病、尿酸盐结晶累积形成痛风石沉积、尿酸性肾结石等。急性期止痛，可以使用全身或关节内糖皮质激素、NSAID、秋水仙碱，难治性痛风发作可尝试使用抑制IL-1β的生物制剂（欧盟已批准卡那单抗治疗难治性痛风发作）。缓解期降尿酸，可以使用别嘌醇、非布司他、丙磺舒、苯溴马龙或聚乙二醇重组尿酸酶。《FAST研究：非布司他与别嘌醇在痛风患者中的长期心血管安全性》LANCET，2020年11月 (10)这项前瞻性、随机、开放、非劣效研究，纳入≥60岁、已经接受别嘌醇治疗的、合并心血管危险因素的患者，共6128人。患者平均年龄71岁，85%为男性，33.4%有心血管疾病病史。被随机分配别嘌醇或非布司他治疗，中位随访时间为1467天。在非致死性心梗或急性冠脉综合征住院的发生率方面，非布司他为1·72次/100人年，低于别嘌醇2·05次/100人年（风险比 0·85，p