Podcasts about bath uk

In this episode, Dr Tsen Vei Lim talks to Dr James MacKillop, a clinical psychologist and professor at McMaster University in Canada, and director for both the Peter Boris Centre for Addictions Research and the Michael G DeGroote Centre for Medicinal Cannabis Research. The interview covers his research report on the diagnostic validity of drinking behaviour for identifying alcohol use disorder (AUD) with findings from a representative sample of community adults and an inpatient clinical sample. · What alcohol use disorder is and how it is currently diagnosed [01:41]· The surprising exclusion of drinking behaviour in AUD diagnosis [03:03]· Unpacking ‘receiver operating characteristic curves' [04:42]· The key findings of the study [05:45]· Whether James' findings will change how we think about diagnosing AUD [07:35]· Why clinicians would benefit collecting how much people are drinking in one session [09:32]· Whether an indicator of heavy drinking would be helpful in treatment settings [10:35]· Bringing objective data into clinical application [12:09]· Whether we can use a similar metric to other drugs, such as cannabis [13:09]· What we can learn for policy and further research [15:56]· The barrier of the lack of biomarkers in alcohol use disorder [18:00]· The take-home message of the paper [19:40]About Tsen Vei Lim: Tsen Vei is an academic fellow supported by the SSA, currently based at the Department of Psychiatry at the University of Cambridge. His research integrates computational modelling, experimental psychology, and neuroimaging to understand the neuropsychological basis of addictive behaviours. He holds a PhD in Psychiatry from the University of Cambridge (UK) and a BSc in Psychology from the University of Bath (UK). About James MacKillop PhD, CPsych, FCAHS: Dr. MacKillop holds the Peter Boris Chair in Addictions Research and a Canada Research Chair in Translational Addiction Research at McMaster University and St. Joseph's Healthcare Hamilton. There, Dr. MacKillop directs both the Peter Boris Centre for Addictions Research and the DeGroote Centre for Medicinal Cannabis Research. Dr. MacKillop trained as a clinical psychologist at Binghamton University and Brown University and studies addiction using a multidisciplinary approach, integrating psychology, economics, neuroscience, and genetics. James receives unrestricted research funding from Canadian Institutes on Health Research, the National Institutes of Health, and Correctional Services of Canada and am a senior scientist and principal in Beam Diagnostics, Inc., a technology transfer start-up company. The latter had no relationship to the publication in Addiction.Original article: Diagnostic validity of drinking behaviour for identifying alcohol use disorder: Findings from a representative sample of community adults and an inpatient clinical sample. https://doi.org/10.1111/add.70037The opinions expressed in this podcast reflect the views of the host and interviewees and do not necessarily represent the opinions or official positions of the SSA or Addiction journal. The SSA does not endorse or guarantee the accuracy of the information in external sources or links and accepts no responsibility or liability for any consequences arising from the use of such information. Hosted on Acast. See acast.com/privacy for more information.

Use promo code 09POD to save 30% on Women of the Mafia: https://www.cornellpress.cornell.edu/book/9781501774799/women-of-the-mafia/ In the UK, use promo code CSANNOUNCE here: https://www.combinedacademic.co.uk/9781501774799/women-of-the-mafia/ Transcript here: https://otter.ai/u/66ZHk_WmYWFLUANWFtixUAe64Sc?utm_source=copy_url Felia Allum is Professor in the department of Politics, Languages and International Studies at the University of Bath (UK). Her research focuses on organized crime, Italian Mafias, criminal mobility, gender and political corruption. She is the award-winning author of The Invisible Camorra. We spoke to Felia about why the conventional wisdom that all women are victims of a male-only mafia that excludes them is false; how women's criminal activities within the mafia of Naples, Italy are hidden for a variety of reasons; and, why in the private sphere women are actually the key to the power of the Neapolitan Camorra and are its very backbone.

This week we're talking about our trip to Bath, England where Erica's expectations were surpassed!

Você está no canal de Podcast O Marketeiro. O tema: Conectando-se com o Público Infantojuvenil: Estratégias de Marketing Digital, Metaverso e Games Neste episódio, convidamos você a explorar o universo do marketing digital direcionado ao público infantojuvenil e familiar, aprendendo com um especialista sobre as estratégias e tendências que estão moldando esse mercado em constante evolução. Junte-se a nós para uma conversa envolvente sobre como as marcas podem se conectar de forma autêntica e responsável com esse público tão especial. Esteja preparado para descobrir como o metaverso, os games e outras inovações digitais estão transformando a maneira como as empresas se comunicam e se relacionam com as crianças e adolescentes de hoje. (*) Ricardo Wako, Formado em Administração de Empresas pela FGV/EAESP, com MBA pela University of Bath/UK, Ricardo Wako conta com vasta experiência no mercado de marketing e publicidade, com passagens por empresas como Johnson & Johnson, Pepsico, Novartis, Semp TCL, Mattel, Hasbro e Ogilvy, Além de responder pela gestão dos investimentos em publicidade destas marcas, Wako liderou diversos projetos de produção de conteúdo. Até o próximo Podcast!

Tyler Spicer, musician, producer and songwriter from Bath UK soon to be in Nashville. This passionate artist has been pivoting his talents in a big way he thanks the covid lockdowns for this change and feels like it was the perfect time for him to move into this production space. Connect with Tyler: Instagram Website YouTube Facebook

Aufzeichnung des 4. Webinars der Power-to-the-People-Gruppe, einer Kooperation aus European Alternatives, European University Institute, Europe Calling, Mehr Demokratie, Another Europe is Possible, Citizens Takeover Europe. Am 22. Juni zum Thema „Klima-Erschöpfung: Wie aus Ohnmacht Veränderung werden kann” Unsere Gäste waren: - Caroline Hickman, Psychologin an der University of Bath (UK), spezialisiert auf Klimapsychologie und Umwelt-Angst, bekannte Rednerin und Autorin - Sven Hillenkamp, Soziologe, Autor und Analytiker der Klimaprotestbewegung mit einer Vorgeschichte in radikalen Protestbewegungen - Terry Reintke, Mitglied des Europäischen Parlaments für die deutsche grüne Partei und Co-Vorsitzende der Grünen/EFA-Fraktion - Matteo Innocenti, Psychiater und Botschafter für den Europäischen Klimapakt - Louis Fidel, Gründungsmitglied der HEC (École des hautes études commerciales Paris) und ehemaliger Präsident der Ökologengesellschaft der HEC - Kira Hoffmann, Vertreterin der Gruppe „Letzte Generation“ in Deutschland

Recording of the 4th webinar of the Power-to-the-People group, a cooperation of European Alternatives, European University Institute, Europe Calling, Mehr Demokratie, Another Europe is Possible, Citizens Takeover Europe. On 22 June on the topic: “Climate Fatigue: How to turn powerlessness into change?” Our guests were: - Caroline Hickman, psychologist at the University of Bath (UK), specialising in climate psychology and environmental anxiety, well-known speaker and author. - Sven Hillenkamp, sociologist, author and analyst of the climate protest movement with a background in radical protest movements - Terry Reintke, Member of the European Parliament for the German Green Party and Co-Chair of the Greens/EFA Group - Matteo Innocenti, psychiatrist and ambassador for the European Climate Pact - Louis Fidel, founding member of the HEC (École des hautes études commerciales Paris) and former President of the Ecology Society of the HEC - Kira Hoffmann, representative of the group "Last Generation" in Germany

On today's show Richard Vobes discusses the up-coming Better Way Conference in Bath UK that he will be speaking at. Richard also discusses recent evidence from the International Covid Inquiry at the EU Parliament that covid and the covid vaccines are a bio-weapon. GUEST OVERVIEW: Richard Vobes, also known as The Bald Explorer and now also as one half of The English Couple. Has a YouTube channel to express concerns over the way things are in the world. Particularly that which affects England.

In this Astronomy Daily podcast episode, new host Tim Gibbs (AstroTim) is joined by Halley to discuss the latest news in space exploration. Private companies like Astrobotic, Intuitive Machines, Mast and Space Systems, Blue Origin, and SpaceX are planning multiple missions to the Moon, some to deliver scientific instruments and payloads, while others will transport humans in the future. SpaceX's Starship rocket prototype achieved launch successfully, but it exploded during its seperation attempt. Thales has successfully demonstrated its ability to protect a demonstration satellite from cyberattacks, highlighting the need for increased cybersecurity measures in space. Astria has launched a new satellite tasking capability in partnership with major satellite imagery providers, enabling customers to request and receive tasking of high-resolution satellite imagery within hours, offering more efficient and cost-effective access to high-resolution satellite imagery. Researchers at USC are collaborating with the software company Tangram Flex to replace the software components within legacy satellites to repurpose them, which could result in cost savings and less space debris. Voyager Two, launched in 1977, has begun using a small reservoir of backup power to keep its five science instruments operating, enabling the mission to postpone shutting down the science instruments until 2026. You can find out more about the low cost observatory being set in in Bath (UK) by visiting their website: https://www.bathecho.co.uk/news/education/low-cost-observatory-students-university-101854/ Available on Apple Podcasts, Spotify, YouTube and wherever you get your podcasts from. Apple Podcasts: https://podcasts.apple.com/us/podcast/astronomy-daily-the-podcast/id1642258990 Spotify: https://open.spotify.com/show/2kPF1ABBW2rCrjDlU2CWLW Or stream from our websites at www.spacenuts.io or our HQ at www.bitesz.com Astronomy Daily The Podcast now has its own YouTube channel – please subscribe (we're a little lonely there) – thank you: www.youtube.com/@astronomydailythepodcast Commercial Free Premium version available with a Space Nuts subscription via Supercast only. Details: https://spacenuts.supercast.com/ Please subscribe to the podcast and if you have a moment, a quick review would be most helpful. Thank you… Please show our sponsor some love. Looking to buy a domain name and establish yourself online for not very much money? Then use the folks we trust all our domains too… NameCheap…and help support the show. To find out more visit www.spacenutspodcast.com/namecheap - thank you. #space #astronomy #science #podcast #astronomydaily #spacenuts #spacetime

This week on SA Voices From the Field, we interviewed Omneya Badr about her own experiences working in student affairs as well as directing efforts of student affairs professionals working in the Middle East, North Africa, and South Asia. Omneya Badr is the current director of MENASA NASPA. MENASA is the Middle East, North Africa, and South Asia region of NASPA. She is a Student Affairs enthusiast who sees a huge potential for growth in the region. Omneya Badr holds the position of Senior Academic Advisor at Qatar University and previously was a lecturer and faculty advisor at NYIT Bahrain (New York Institute of Technology). Omneya has gained a culturally diverse experience studying, teaching, and working for over 20 years in the USA, UK, Egypt, Bahrain, and Qatar. Omneya is a frequent presenter at NASPA and NACADA conferences. Her research interest is culturally based on Academic Advising, branding higher education, MENA First-generation students, cross-cultural communication, Student Success initiatives, FYE, and education as a soft power. Omneya holds an MBA from the University of Bath – UK, a Certificate of Entrepreneurial & Small Business Operation from the Academy of Arts, California - USA, and a BA in Management from the American University in Cairo - Egypt. In addition, she recently acquired a Diversity, Equity and Inclusion in the Workplace Certificate from the University of South Florida - USA.  As an educator, Omneya is highly interested in developing professional development venues in the MENA regions and encouraging Student Affairs Professionals to research and share knowledge. Please subscribe to SA Voices from the Field on your favorite podcasting device and share the podcast with other student affairs colleagues!

On the show today is Ed Maunder. Ed is an exercise physiologist with expertise in metabolic responses to endurance exercise, and metabolic adaptations to endurance training. Ed is a Lecturer in the School of Sport and Recreation and part of the Sport Physiology and Nutrition Research Group at SPRINZ. Ed is also a British Association of Sport and Exercise Science (BASES) accredited applied exercise physiology practitioner in the Sports Performance Clinic at AUT Millennium. Ed holds a BSc (Hons) in Sport and Exercise Science from the University of Bath (UK), an MRes from the University of Birmingham (UK), and a PhD from AUT. Ed won the 2018 BASES Masters Dissertation of the Year Award for his work on carbohydrate nutrition in recovery from acute exhaustive endurance exercise. Ed was awarded a prestigious Education New Zealand International Doctoral Research Scholarship for his PhD, which investigated the effect of exposure to environmental heat stress on acute metabolic responses to endurance exercise, and skeletal muscle and metabolic adaptations to endurance training.Links to EdTwitter: https://twitter.com/maunder_ed?lang=en Researchgate: https://www.researchgate.net/profile/Ed-Maunder/research Oxidative Potential Podcast LinksMoxy Monitor Discount:For a 5% discount on a Moxy Monitor purchase use promocode: OXPOhttps://www.moxymonitor.com/Instagram Links:https://www.instagram.com/criticalo2/?hl=enhttps://www.instagram.com/resiliencehpc/?hl=enYoutube Links:https://www.youtube.com/channel/UCfkBVklDMTPMbaPw0ikG2tgWebsite Links:https://www.resiliencehpc.ca/

Videos: All Found on Youtube TikTok Is Worse Than You Thought Joe Reviews TikTok's Crazy Terms of Service   HEALTH NEWS  Lutein may counter cognitive aging, study finds A stable gut helps elite athletes perform better Could Spirulina modify the microbiome to protect against age-related damage? It doesn't matter much which fiber you choose—just get more fiber Plant-based meat ‘healthier and more sustainable than animal products,' according to new study Pine Bark Extract Treats Meniere's Disease Lutein may counter cognitive aging, study finds University of Illinois, July 25, 2022 Spinach and kale are favorites of those looking to stay physically fit, but they also could keep consumers cognitively fit, according to a new study from University of Illinois researchers. The study, which included 60 adults aged 25 to 45, found that middle-aged participants with higher levels of lutein – a nutrient found in green leafy vegetables such as spinach and kale, as well as avocados and eggs — had neural responses that were more on par with younger individuals than with their peers. The findings were published in the journal Frontiers in Aging Neuroscience. “Now there's an additional reason to eat nutrient-rich foods such as green leafy vegetables, eggs and avocados,” said Naiman Khan, a professor of kinesiology and community health at Illinois. “We know these foods are related to other healthbenefits, but these data indicate that there may be cognitive benefits as well.” Lutein is a nutrient that the body can't make on its own, so it must be acquired through diet. Lutein accumulates in brain tissues, but also accumulates in the eye, which allows researchers to measure levels without relying on invasive techniques. The Illinois researchers measured lutein in the study participants' eyes by having participants look into a scope and respond to a flickering light. Then, using electrodes on the scalp, the researchers measured neural activity in the brain while the participants performed a task that tested attention. “The neuro-electrical signature of older participants with higher levels of lutein looked much more like their younger counterparts than their peers with less lutein,” Walk said. “Lutein appears to have some protective role, since the data suggest that those with more lutein were able to engage more cognitive resources to complete the task.” Next, Khan's group is running intervention trials, aiming to understand how increased dietary consumption of lutein may increase lutein in the eye, and how closely the levels relate to changes in cognitive performance. A stable gut helps elite athletes perform better Anglia Ruskin University, July 29, 2022 New research has found that microbial instability in the gut could hinder the performance of elite endurance athletes, and that short-term, high-protein diets are associated with this type of imbalance. Researchers from across the UK analyzed the performance and gut health of a group of well-matched, highly trained endurance runners, to explore the impact of both high-protein and high-carbohydrate diets. The study found that in those following a high-protein regime, this resulted in a disturbance in the stability of the gut microbiome. This was also accompanied by a 23.3% reduction in time trial performance. Analysis found a significantly reduced diversity and altered composition of the gut phageome, as well as higher levels of certain types of virals and bacterial compartments. Those participants whose gut microbiome was more stable performed better during time trials. Those following a high-carbohydrate diet resulted in an improved time trial performance of 6.5%. Could Spirulina modify the microbiome to protect against age-related damage? Louvain Drug Research Institute (Belgium), July 28, 2022 Spirulina might help protect against age-related liver inflammation by modifying pathways in the microbiome, say researchers. Consumption of spirulina could help protect against hepatic inflammation in the elderly, according to the new animal research published in Nutrients. Belgian researchers carried out tests on mice, which suggest that the algae Spirulina has an impact on the gut microbiota, which in turn activates the immune system in the gut and improves inflammation in the liver that is associated with ageing. Led by senior author Professor Nathalie Delzenne from the Louvain Drug Research Institute in Belgium, the team said oral feeding of Spirulina was found to modulates several immunological functions involving, among others, the TLR4 pathway in old mice. “The fact that its oral consumption can influence both gut immunity and systemic sites, such as the liver, suggests that its immune action is not confined to the gut immune system,” wrote the team – who said the findings open the way to new therapeutic tools “in the management of immune alterations in aging, based on gut microbe-host interactions.” Furthermore, they suggested that improvement of the homeostasis in the gut ecosystem ‘could be essential' during the aging process, “and, in this perspective, dietary manipulation of the gut microbiota of the elderly with Spirulina, may represent a tool for preserving a healthy gastrointestinal microbial community in addition to its beneficial effects on immune function.” It doesn't matter much which fiber you choose—just get more fiber Duke University, July 30, 2022 That huge array of dietary fiber supplements in the drugstore or grocery aisle can be overwhelming to a consumer. They make all sorts of health claims too, not being subject to FDA review and approval. So how do you know which supplement works and would be best for you? A rigorous examination of the gut microbes of study participants who were fed three different kinds of supplements in different sequences concludes that people who had been eating the least amount of fiber before the study showed the greatest benefit from supplements, regardless of which ones they consumed. “The people who responded the best had been eating the least fiber to start with,” said study leader Lawrence David, an associate professor of molecular genetics and microbiology at Duke University. When your gut bugs are happily munching on a high-fiber diet, they produce more of the short-chain fatty acids that protect you from diseases of the gut, colorectal cancers and even obesity. And in particular, they produce more of a fatty acid called butyrate, which is fuel for your intestinal cells themselves. Butyrate has been shown to improve the gut's resistance to pathogens, lower inflammation and create happier, healthier cells lining the host's intestines. “We didn't see a lot of difference between the fiber supplements we tested. Rather, they looked interchangeable,” David said during a tour of his sparkling new lab in the MSRB III building Plant-based meat ‘healthier and more sustainable than animal products,' according to new study University of Bath (UK), July 30, 2022 Plant-based dietary alternatives to animal products are better for the environment and for human health when compared with the animal products they are designed to replace, say the authors of a new study. A new paper published in Future Foods argues that because these foods are “specifically formulated to replicate the taste, texture, and overall eating experience of animal products,” they are a much more effective way of reducing demand for meat and dairy than simply encouraging people to cook vegetarian whole foods. The study, conducted by psychologists at the University of Bath, concludes that plant-based meat and dairy alternatives “offer a healthier and more environmentally sustainable solution which takes into account consumer preferences and behavior.” The review examined 43 studies into the health and environmental impacts of plant-based foods, as well as consumer attitudes. One study found that almost 90% of consumers who ate plant-based meat and dairy were in fact meat-eaters or flexitarians; another found that plant-based products with a similar taste, texture, and price to processed meat had the best chance of replacing meat. The paper also found that these plant-based products caused lower levels of greenhouse gas emissions than the animal products they were replacing. One paper found replacing 5% of German beef consumption with pea protein could reduce CO2emissions by up to eight million tons a year. Another found that compared to beef burgers, plant-based burgers were associated with up to 98% less greenhouse gas emissions. Studies focusing on the healthiness of plant-based products also found they tend to have better nutritional profiles compared to animal products, with one paper finding that 40% of conventional meat products were classified as ‘less healthy' compared to just 14% of plant-based alternatives based on the UK's Nutrient Profiling Model. Others found plant-based meat and dairy were good for weight loss and building muscle mass, and could be used to help people with specific health conditions. Food producers may be able to add ingredients such as edible fungi, microalgae or spirulina to plant-based foods, boosting properties such as amino acids, vitamins B and E and antioxidants. Future innovations in processing and ingredients are likely to lead to further nutritional improvements. Pine Bark Extract Treats Meniere's Disease University of Chieti-Pescara (Italy), July 17, 2022  Research from Italy's University of Chieti-Pescara has found that a patented pine bark extract significantly treats Meniere's disease. Ménière's disease is a type of vertigo caused by a condition of the inner ear, discovered by the French doctor, Prosper Ménière in the mid-nineteenth century. Dr. Ménière found the vertigo disorder, which produces a low-pitched tinnitus of varying intensity depending upon the person and the degree of the condition; can eventually result in a complete loss of hearing. Symptoms include periodic headaches, dizziness, nausea and vomiting along with vertigo attacks that can last hours to weeks. The researchers studied 107 patients with Ménière's disease – each with varying intensity of symptoms. The researchers split the 120 patients into two groups and for six months, and both groups were given conventional treatment. In addition, one group was given 150 milligrams per day of Pycnogenol – a patented pine bark extract from the French Maritime pine tree. They found that after three months of treatment, the pine bark extract group showed significantly better improvement than the control group. A full 45 percent of the pine bark extract group had a complete recovery after three months compared to 23 percent of the placebo group. After six months, a full 87 percent of the pine bark extract group experienced recovery – became asymptomatic. Meanwhile, 34 percent of the control group (conventional treatment) recovered after six months. The patients were given 200 milligrams per day of Pycnogenol for 8 weeks and crossed over with a placebo.

First trial to prove a diet supplement can prevent hereditary cancer Newcastle University (UK), July 25, 2022 A trial in people with high hereditary risk of a wide range of cancers has shown a major preventive effect from resistant starch, found in a wide range of foods such as oats, breakfast cereal, cooked and cooled pasta or rice, peas and beans, and slightly green bananas. An international trial—known as CAPP2—involved almost 1000 patients with Lynch syndrome from around the world, and revealed that a regular dose of resistant starch, also known as fermentable fiber, taken for an average of two years, did not affect cancers in the bowel but did reduce cancers in other parts of the body by more than half. This effect was particularly pronounced for upper gastrointestinal cancers including esophageal, gastric, biliary tract, pancreatic and duodenum cancers. The astonishing effect was seen to last for 10 years after stopping taking the supplement. "We found that resistant starch reduces a range of cancers by over 60%. The effect was most obvious in the upper part of the gut," explained Professor John Mathers, professor of Human Nutrition at Newcastle University. "This is important as cancers of the upper GI tract are difficult to diagnose and often are not caught early on. "Resistant starch can be taken as a powder supplement and is found naturally in peas, beans, oats and other starchy foods. The dose used in the trial is equivalent to eating a daily banana; before they become too ripe and soft, the starch in bananas resists breakdown and reaches the bowel where it can change the type of bacteria that live there. "Resistant starch is a type of carbohydrate that isn't digested in your small intestine; instead it ferments in your large intestine, feeding beneficial gut bacteria—it acts, in effect, like dietary fiber in your digestive system. This type of starch has several health benefits and fewer calories than regular starch. We think that resistant starch may reduce cancer development by changing the bacterial metabolism of bile acids and to reduce those types of bile acids that can damage our DNA and eventually cause cancer. However, this needs further research."   New study finds lowest risk of death was among adults who exercised 150-600 minutes/week Harvard School of Public Health, July 25, 2022 An analysis of more than 100,000 participants over a 30-year follow-up period found that adults who perform two to four times the currently recommended amount of moderate or vigorous physical activity per week have a significantly reduced risk of mortality, according to new research published today in the American Heart Association's journal Circulation. The reduction was 21-23% for people who engaged in two to four times the recommended amount of vigorous physical activity, and 26-31% for people who engaged in two to four times the recommended amount of moderate physical activity each week. In 2018, the United States Department of Health and Human Services' Physical Activity Guidelines for Americans recommended that adults engage in at least 150-300 minutes/week of moderate physical activity or 75-150 minutes/week of vigorous physical activity, or an equivalent combination of both intensities.  The analysis also found: Participants who met the guidelines for vigorous physical activity had an observed 31% lower risk of CVD mortality and 15% lower risk of non-CVD mortality, for an overall 19% lower risk of death from all causes. Participants who met the guidelines for moderate physical activity had an observed 22-25% lower risk of CVD mortality and 19-20% lower risk of non-CVD mortality, for an overall 20-21% lower risk of death from all causes. Participants who performed two to four times above the recommended amount of long-term vigorous physical activity (150-300 min/week) had an observed 27-33% lower risk of CVD mortality and 19% non-CVD mortality, for an overall 21-23% lower risk of death from all causes. Participants who performed two to four times above the recommended amount of moderate physical activity (300-600 min/week) had an observed 28-38% lower risk of CVD mortality and 25-27% non-CVD mortality, for an overall 26-31% lower risk of mortality from all causes. In addition, no harmful cardiovascular health effects were found among the adults who reported engaging in more than four times the recommended minimum activity levels. Previous studies have found evidence that long-term, high-intensity, endurance exercise, such as marathons, triathlons and long-distance bicycle races, may increase the risk of adverse cardiovascular events, including myocardial fibrosis, coronary artery calcification, atrial fibrillation and sudden cardiac death.   Treating dementia with the healing waves of sound Ultrasound applied to the brain could help treat patients with dementia. Tohoku University (Japan), July 20, 2022 Ultrasound waves applied to the whole brain improve cognitive dysfunction in mice with conditions simulating vascular dementia and Alzheimer's disease. The research, conducted by scientists at Tohoku University in Japan, suggests that this type of therapy may also benefit humans. The team, led by cardiologist Hiroaki Shimokawa, found that applying low-intensity pulsed ultrasound (LIPUS) to the whole brain of the mice improved blood vessel formation and nerve cell regeneration without having obvious side effects. "The LIPUS therapy is a non-invasive physiotherapy that could apply to high-risk elderly patients without the need for surgery or anaesthesia, and could be used repeatedly," says Shimokawa. The Tohoku University team found that cognitive impairment markedly improved in mice with conditions similar to vascular dementia and Alzheimer's disease when LIPUS was applied to the whole brain three times a day for 20 minutes each time.    Study: ADHD drugs do not improve cognition in healthy college students University of Rhode Island, July 19, 2022 Contrary to popular belief across college campuses, attention deficit hyperactivity disorder (ADHD) medications may fail to improve cognition in healthy students and actually can impair functioning, according to a study by researchers at the University of Rhode Island and Brown University. Study co-investigators Lisa Weyandt, professor of psychology and a faculty member with URI's George and Anne Ryan Institute for Neuroscience, and Tara White, assistant professor of research in behavioral and social sciences at Brown University, had anticipated different findings. "We hypothesized that Adderall would enhance cognition in the healthy students, but instead, the medication did not improve reading comprehension or fluency, and it impaired working memory," she said. "Not only are they not benefitting from it academically, but it could be negatively affecting their performance." This first-ever multisite pilot study of the impact of so-called "study drugs" on college students who do not have ADHD comes at a time when use of prescription stimulants such as Adderall, Ritalin and Vyvanse is common among young adults who believe the drugs will improve their academic performance.  Results of the study, published in the journal Pharmacy, show that the standard 30 mg dose of Adderall did improve attention and focus -- a typical result from a stimulant -- but that effect failed to translate to better performance on a battery of neurocognitive tasks that measured short-term memory, reading comprehension and fluency. Weyandt has a theory about why working memory would be adversely affected by the medication. Brain scan research shows that a person with ADHD often has less neural activity in the regions of the brain that control executive function -- working memory, attention, self-control. For people with ADHD, Adderall and similar medications increase activity in those regions and appear to normalize functioning. "If your brain is functioning normally in those regions, the medication is unlikely to have a positive effect on cognition and my actually impair cognition. In other words, you need to have a deficit to benefit from the medicine," Weyandt said.         Guanabana: the cancer killer big pharma doesn't want you to know about Northeastern University, July 16, 2022  Guanabana is known by a variety of names -- including soursop, cherimoya, custard apple, Brazilian paw paw and graviola. As far back as the 1970s, the National Cancer Institute (NCI) investigated the merits of guanabana, and discovered the stems and leaves of the tree were successful in destroying cancer cells. "Inexplicably, the results [of the NCI research] were published in an internal report and never released to the public. Since 1976, guanabana has proven to be an immensely potent cancer killer in 20 independent laboratory tests, but as of now, no double-blind clinical trials," reports Christopher Lane, Ph.D., in Psychology Today. Moreover, this study found that a compound derived from the leaves of guanabana was "selectively cytotoxic for the lung (A-549), colon (HT-29), and pancreatic (PACA-2) cell lines with potencies equal to or exceeding those of Adriamycin." And research in the Journal of Natural Products discovered that extracts of guanabana demonstrated pesticidal, antimalarial, antiviral and antimicrobial properties. Likewise, Memorial Sloan Kettering Cancer Center states that guanabana shows anti-inflammatory and anticancer effects in vitro and in vivo. Revered for centuries in South America and Southeast Asia, the bark, leaves, root, seeds and fruit have been used to tame heart disease, asthma, liver issues and arthritis. Guanabana is also helpful for treating sleep disorders, fevers and cough. According to the article, "Guanabana--Medicinal Uses?" extracts of the plant: Attack cancer safely and effectively with an all-natural therapy that does not cause extreme nausea, weight loss and hair loss. Protect the immune system. Boost energy and outlook on life. Effectively target and kill malignant cells in 12 types of cancer -- including colon, breast, prostate, lung and pancreatic cancer. Proved to be up to 10,000 times stronger in slowing the growth of cancer cells than Adriamycin, a commonly used chemotherapeutic drug. Selectively kill only cancer cells, unlike traditional chemotherapy treatments.  *A word of caution: Excessive consumption of guanabana can lead to neuronal dysfunction and degeneration with symptoms similar to Parkinson's disease. Consult with a qualified practitioner before taking guanabana on a daily basis.     High-strength cannabis linked to addiction and mental health problems University of Bath (UK), July 25, 2022 As the strength or potency of cannabis products has increased internationally over the years, so have rates of people being treated for cannabis addiction, say the authors of a new study. Researchers from the Addiction and Mental Health Group at the University of Bath (UK) have systematically analyzed the relationship between the types of cannabis people use and their addiction and mental health problems. Their work draws on 20 studies involving almost 120,000 people. The new study, published in The Lancet Psychiatry, suggests that people who use high-potency cannabis are more likely to experience addiction than those using low-potency products. It also suggests that people using high-potency cannabis are more likely to experience a psychotic disorder, such as schizophrenia. These findings may help to explain why more people have received treatment for cannabis problems over recent years. Data from the European Monitoring Centre for Drugs and Drug Addiction show a 76% increase in people entering treatment for cannabis addiction in the past decade.

Who wouldn't want to visit a library made up of first editions from Golden Age authors? That's the premise of The First Edition Library series by Marty Wingate. Haley is a curator at the unique private library in Bath. The third book in the series, “The Librarian Always Rings Twice” delves into the fun Books About Books trope. It's a story rich in layers with mysteries in the main storyline as well as in the story within the story.Read-alike recommendations include contemporary cozies by Martie Wingate, books set in Bath UK, and books about books.What's your favorite book or series about books?

We're in Bath, U.K., with my good friend AJ Saunders of AJSDigitalGroup.com. We talk about exploring the Royal Crescent, visiting the Jane Austen Museum, and relaxing in Roman bath houses. Show notes are at https://WeTravelThere.com/bath Miles and points make travel affordable, but tracking them is difficult. That's why I use AwardWallet to monitor my rewards, reservations, and free night certificates. Sign up for free at WeTravelThere.com/awardwallet.

Coaching Uncaged Season 12, Episode 10: Dr. Peter Hawkins: Coaching and Climate Change In this episode of Coaching Uncaged, our host, Coach and Positive Psychologist Yannick Jacob, is joined by Dr. Peter Hawkins. Peter Hawkins, Chairman of Renewal Associates, co-founder of the Global Team Coaching Institute, Emeritus Professor of Leadership at Henley Business School, and Senior Visiting Fellow, Civil Service College (Singapore), is a leading consultant, coach, writer and researcher in organisational strategy, leadership, culture change, team and board development and coaching. He has worked with many leading organisations all over the world including Europe, Asia, Middle East, South Africa, and America coaching Executive Teams and Boards and facilitating major change and organisational transformation projects. He has coached over 100 boards and senior executive teams, enabling them to develop their purpose, vision, values, collective leadership and strategy for the future, in a wide range of international, large and small commercial companies, government departments, NHS Trusts, professional services organisations and charities. Peter is an international thought leader in Systemic Coaching, Executive Teams and Board Development, President of both the Association of Professional Executive Coaching and Supervision (www.apecs.org ); and the Academy of Executive Coaching (www.aoec.com) and a Fellow of the Royal Society of Arts and the Windsor Leadership Trust. He has been a keynote speaker at many international conferences on the learning organisation, leadership and executive coaching and teaches and leads masterclasses in over 50 different countries round the world. He is the author of many best-selling books and papers in the fields of Leadership, Board and Team Coaching, Systemic Coaching, Supervision and Organizational Transformation (including Leadership Team Coaching, Kogan Page; 2011 (4th edition, 2021); Leadership Team Coaching in Practice (3rd edition 2022, Systemic Coaching (with Eve Turner (Routledge 2020); Coaching, Mentoring and Organizational Consultancy: Supervision, Skills and Development (with Nick Smith), McGraw-Hill/Open University Press, (2nd ed, 2013); Creating a Coaching Culture, McGraw Hill, 2012; and The Wise Fool's Guide to Leadership, O Books, 2005; Supervision in the Helping Professions (5th edition 2020 with Aisling McMahon) McGraw Hill and Integrative Psychotherapy (2020 with Judy Ryde) Jessica Kingsley. Peter was joint founder, in 1986, of Bath Consultancy Group and its chairman until the company was sold in 2010 and has chaired three other company boards as well as being a trustee director of several charities. He lives on the edge of Bath UK with 37 acres which he shares, with many animals and trees as well as his children and grandchildren and leaders who come on courses and retreats.

De Camille is an artist who serves her mission, offering complimentary private video consultations to help remind you to be more gentle and loving with yourself. A native Angeleno, De Camille attended the Lycee Francais at age six and went on to study art and fashion at the Paris American Academy and the Ecole des Beaux Arts in Paris where she had a one-woman sell-out show in Montmartre. The world of the French Cabaret has continued to inspire her work. There is a sense of the collector and traveler in her work having lived abroad for five years. From the Caribbean islands of Montserrat and Grenada to Paris and Bath UK, she takes from the past to update it through her unique and quirky lens. Her work is a synthesis of Pop Culture through a dream-like state; her technique is layered. It may start with the collaging of a Blue Print and images to set the scene or create the impressions for the structure of the work. She experiments with various mediums to create altered states of texture such as; saw dust, paint medium; egg yolk; tea bags; paper; found objects. Her varied style lends itself to the commission work she is presently creating with her private collectors. Presently she is living and painting in West Linn, Oregon, with her young family. View the Gallery: www.CoolArtHouse.com

The aim of the ERC-ESICM guidelines on temperature control after cardiac arrest in adults is to provide evidence-based guidance in adults who are comatose after resuscitation from either in-hospital or out-of-hospital cardiac arrest, regardless of the underlying cardiac rhythm. These guidelines replace the recommendations on temperature management after cardiac arrest included in the 2021 post-resuscitation care guidelines co-issued by the European Resuscitation Council (ERC) and the European Society of Intensive Care Medicine (ESICM). The invited experts of this podcast, Prof Sandroni and Prof Nolan, describe the methodology followed and explain the panel suggestions on guideline implementation and the identified priorities for future research. Listen to their interview! Original article: https://rdcu.be/cGdbg (ERC‑ESICM guidelines on temperature control after cardiac arrest in adults) Speakers Claudio SANDRONI. Department of Intensive Care, Emergency Medicine and Anaesthesiology, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Rome (IT). Chair of the ESICM Trauma & Emergency Medicine Section. Jerry P. NOLAN. School of Clinical Science, University of Bristol, Bristol, UK and Department of Anaesthesia and Intensive Care Medicine, Royal United Hospital, Bath (UK). Laura BORGSTEDT. Clinic for Anaesthesiology and Intensive Care Medicine and University of Munich (DE). ESICM NEXT Committee Member.

Vegetarians have 14% lower cancer risk than meat-eaters, study finds   Oxford University, February 24, 2022   Vegetarians have a 14% lower chance of developing cancer than carnivores, according to a large study that links meat-eating to a heightened risk of the disease. A team of researchers from Oxford University analysed data on more than 470,000 Britons and found that pescatarians had a 10% reduced risk. Compared with people who eat meat regularly – defined as more than five times a week – those who consumed small amounts had a 2% lower risk of developing cancer, the study found.   (NEXT)   Dietary Lutein Modulates Growth and Survival Genes in Prostate Cancer Cells   Indiana University School of Medicine, February 26, 2022   Reports from Indiana University School of Medicine Provide New Insights that Dietary Lutein Modulates Growth and Survival Genes in Prostate Cancer Cells) According to news originating from Indianapolis, Indiana, research stated, "Lutein is a carotenoid pigment present in fruits and vegetables that has anti-inflammatory and antitumor properties. In this study, we examined the effect of lutein on proliferation and survival-associated genes in prostate cancer (PC-3) cells." Our news journalists obtained a quote from the research from the Indiana University School of Medicine, "We found that in vitro culture of PC-3 cells with lutein induced mild decrease in proliferation that improved in combination treatment with peroxisome proliferator-activated receptor gamma (PPAR gamma) agonists and other chemotherapeutic agents. Flow cytometry analyses showed that lutein improved drug-induced cell cycle arrest and apoptosis in prostate cancer. Gene array and quantitative reverse transcription-polymerase chain reaction analyses showed that lutein altered the expression of growth and apoptosis-associated biomarker genes in PC-3 cells."   (NEXT)   Walnuts may support sperm health, according to new animal research   University of Delaware, Feb. 28, 2022    New animal research suggests eating a walnut-enriched diet may improve sperm quality by reducing lipid peroxidation, a process that can damage sperm cells. This form of cell damage harms sperm membranes, which are primarily made up of polyunsaturated fatty acids (PUFAs). Walnuts are the only tree nut that are predominantly comprised of PUFAs (one ounce contains 13 grams of PUFAs out of 18 grams of total fat). Research on the health benefits of PUFAs has advanced and most recently the 2015-2020 Dietary Guidelines for Americans has emphasized this type of fat as a replacement for saturated fats. As this is an animal study, there is no direct correlation to processes that occur in the human body. However, the findings support previous research suggesting that walnuts provide key nutrients that may be essential for sperm function.   (NEXT)   Broccoli and kale microgreens pack a nutritional punch that varies with growing conditions   American Chemical Society, February 15, 2022   Although microgreens were initially gourmet ingredients for upscale restaurants, they've become popular among gardeners and home cooks. Despite their “superfood” label, the levels of healthful compounds, such as phytonutrients, in most varieties of microgreens are unknown. Researchers in ACS Food Science & Technology now report that kale and broccoli microgreens grown in either windowsills or under commercial growing conditions are rich in phytonutrients, though the levels of some compounds varied considerably between the two environments.   (NEXT)   Sugar's molecular link to Alzheimer's: Study   University of Bath (UK), February 25, 2022   A "tipping point" molecular link between the blood sugar glucose and Alzheimer's disease has been established by scientists for the first time, who have shown that excess glucose damages a vital enzyme involved with inflammation response to the early stages of Alzheimer's. Abnormally high blood sugar levels, or hyperglycaemia, is well-known as a characteristic of diabetes and obesity, but its link to Alzheimer's disease is less familiar. Scientists already knew that glucose and its break-down products can damage proteins in cells via a reaction called glycation but the specific molecular link between glucose and Alzheimer's was not understood. But now scientists from the University of Bath Departments of Biology and Biochemistry, Chemistry and Pharmacy and Pharmacology, have unraveled that link.   (RFK)   Adam Nagourney's recent effort to cancel and condemn Robert Kennedy Jr. has registered another low in the New York Times' registry of crank tabloid journalism.  Americans' trust in our media is already at an all time low, down to 21 percent last year, and the lowest in the world. The Times' propensity for fake reporting undoubtedly has contributed to American journalism's steady decline. So if a journalist is clueless about the individual he is writing about, what better weapon to employ than Robert's own family members and friends?  Fortunately Nagourney's article is just a rambling, incoherent diatribe recycling earlier Times hit pieces by Roni Rabin and Robert's niece Dr. Kerry Kennedy Meltzer. Its message is that Robert has turned his life away from being a conscientious advocate for the environment and jumped on the conspiratorial bandwagon. However, there are glaring flaws in Nagourney's reasoning that his apparent ignorance about the subject matter would account for. Nowhere does Nagourney mention Robert's international bestselling book The Real Anthony Fauci, which has caused such a stir worldwide. Did the author bother to read the book?  Highly doubtful. Nagourney's writing seemingly focuses on Hollywood and LBGT issues.  Evidently he is not the ideal journalist for the Times' editorial management to assign an article that otherwise requires many years of research into our nation's federal health system and reams of legal documents and peer-reviewed studies about vaccine efficacy and safety. Robert is publicly on record inviting anyone who wishes to debate and challenge his book's content and the over 2,100 references supporting its claims. Would any of the Times' journalists, who hide behind their quills, have the courage to accept his invitation? To our knowledge nobody from the mainstream media has taken up Robert's offer. We might challenge the Times' editorial management to unearth a single instant where Robert has stated he was not pro-vaccine.  If the Times is so worried about Kennedy being on the wrong side of history and science, then why not review The Real Anthony Fauci with reliable, independent fact checkers to debunk any misstatements and untruths? The fact that the Times and the mainstream media have in unison ignored the book entirely, hoping it will fade away into obscurity, is itself gross negligence. Even Fauci and Bill Gates have failed to satisfactorily make a concerted effort to exonerate themselves from the book's damning evidence. If the Times' fraudulent charge is guilt by association, then yes indeed Robert has a fan base among tens of thousands of anti-vaccination parents across the nation with vaccine-damaged children. But this follows the kind of illogic that Bill Clinton, Bill Gates and Allen Dershowitz should be behind bars for their fellowship with Jeffrey Epstein. Repeatedly, Robert is very succinct about being pro-vaccine and he has reason to be very worried about the credibility of vaccine makers' clinical trial data and the deep conflicts of interest between the drug industry and federal regulators who are too willing and eager to give their Big Pharm masters a green light to licensure. That Nagnourney would resurrect the old vaccine-autism chestnut is to be expected of any hit person assigned to target an anti-vaxxer. Yet there is very sound evidence to support Robert's stance on the vaccine-autism debate. We may recall that it was Robert who filed the Freedom of Information request to uncover the smoking gun behind a CDC study showing that there was indeed a relationship between earlier thimerosal (mercury)-laced vaccines and neurological disorders, including autism. The evidence is clearly outlined in the transcript of a 2000 secret meeting held at the Simpsonwood retreat facility outside CDC headquarters in Atlanta.  During the meeting, the study's chief scientist, Dr. Thomas Verstraeten, stated, “This analysis suggests that in our study population, the risks of tics, ADD, language and speech delays, and developmental delays in general may be increased by exposures to mercury from thimerosal-containing vaccines during the first six months of life.”  The clandestine Simpsonwood gathering decided to withhold its findings from the public and, instead, proceed with a recalculation of the same data by employing confounders, or biased criteria selection in order to confirm the CDC's desired results. Later a House Committee on Government Reform's three-year review of the CDC's and FDA's handling of the exponential rise in autism concluded that “It appears that many who participated in the thimerosal debates allowed their standards to be dictated by their desire to disprove an unpleasant theory.” Dr Roger Bernier confirmed a deep concern Robert has been sounding for years to the mainstream media's plugged ears. During the Committee hearings, Dr. Bernier, who was then the CDC's associate director of science, stated, “It [removing thimerosal from vaccines] could entail financial losses of inventory if current vaccine inventory is wasted. It could harm one or more manufacturers and may then decrease the number of suppliers… The evidence justifying this kind of abrupt policy change [immediate removal of mercury from all vaccines] does not appear to exist, and it could entail financial losses for all existing stocks of vaccines that contain thimerosal.” In other words, for the CDC, then as now, protecting pharmaceutical interests and money trump public health and well-being. The Real Anthony Fauci is riddled with similar examples of financial incentives driving health policies directly under Fauci's control. Finally, the Commission recommended that “studies be conducted that pool the results of independent research that has been done thus far, and a comprehensive approach should be developed to rid humans, animals and the environment from this dangerous toxin.” Yet unsurprisingly a subsequent CDC study, after several attempts to massage the original data, was published to deny any relationship between vaccination and autism. This remains the position of the CDC, FDA and HHS despite a large body of independent research, with no conflict of interests with governmental and private industry interests, continues to mount against our policy makers' reliance on tabloid science. Separate from Robert, cases have been adjudicated through the Justice Department to award monetary compensation to victims of vaccine-related autism and encephalitis. However, most dramatic is the whistleblower case of Dr. William Thompson, a senior CDC epidemiologist. Dr. Thompson released thousands of documents to Prof. Brian Hooker, a biologist at Simpson University, providing evidence that the CDC under Julie Gerberding's watch, withheld and later destroyed research data proving the MMR vaccine contributed to higher autism rates in African American boys The documents also proved the CDC has known for years that the influenza vaccines, which still contain mercury, contributed to neurological tics and disorders. If we can easily find these references, certainly it is within the Times' capability to do so also. We should lend an attentive ear to Robert's Covid vaccine warnings because on many occasions in the past he has been on the correct side of history. Perhaps Nagourney's conflating the safety profiles between the experimental mRNA and adenovirus vector Covid injections from traditional pre-Covid vaccines. For example, Robert was a lead attorney in the historic ruling against Monsanto and its carcinogenic glyphosate herbicide or Roundup. The latest legal update is that Monsanto has settled nearly 100,000 lawsuits and paid out $11 billion. Another 26,000 cases remain pending. Throughout his law career Robert has been involved in hundreds of legal cases to protect the environment such as New York City's watershed; enforcement of the Clean Water Act; protecting poor minority, indigenous communities, and military personnel from corporate and federal toxic pollution; and legal victories against the oil, hydrofracking, pipeline and nuclear power industries. Last year, Robert's Children's Health Defense (CHD) won a US Court of Appeals case against the Federal Communications Commission for the agency's failure to review the health and safety guidelines on 5G and other wireless technology. In 2019, 26,000 scientists submitted a petition to the UN, World Health Organization, European Union and world governments demanding a halt to a 5G rollout. There are over 10,000 peer-reviewed studies now warranting global caution about radio frequency radiation's adverse effects to the environment and human DNA, the endocrine system and various organs. Undoubtedly the CHD case unsettled the New York Times; it may be a reason among others for the newspaper to print vindictive articles against Robert. Following the Times' partnership with the telecom giant Verizon to launch a 5G Journalism Lab, the paper's 5G coverage has consistently parroted the telecom industry's talking points. The Verizon collaboration will provide the newspaper with a jump start ahead of other mainstream media to gain “early access the 5G network.” Nor should we forget that the Times' top shareholder is Mexican billionaire and mobile phone magnate Carlos Slim, who is positioned to rake in billions from 5G's rollout south of the border. We might ask why Robert would risk tarnishing the Kennedy legacy, which his siblings seem determined to keep pristine? Quite simply, like his father and uncle, Bobby is a rebel at heart who seeks the truth rather than to preserve a family legacy or bureaucratic ideology. As for the New York Times, on matters of critical domestic and international importance, it has repeatedly proven to be unreliable. This is the same Times, despite its enormous resources and government contacts that has gotten its stories wrong at the cost of countless lives. It got the story of Iraq's weapons of mass destruction reprehensibly wrong, which led to one of the greatest debacles in foreign policy in this century. It got Libya, Venezuela, and Syria wrong. It was wrong about the Obama-Clinton backed coup spearheaded by Hillary sidekick Victoria Nuland.  And to this day the Times has failed to hold the US's co-responsibility for prolonging the Saudis' genocide in Yemen. And the Gray Lady refuses to cover other nations' success stories in their handling the pandemic, including prescribing repurposed inexpensive drugs such as ivermectin which has reduced SARS-2 infections and deaths dramatically. Had Nagourney, Rabin and Robert's siblings and friends spent thousands of hours doing meticulous research to uncover the truth, it would be less likely they would have proceeded in advancing their shared conspiratorial delusions. In the absence of any observable scientific background, to denigrate Robert with personal biases and dogmatic assumptions is disingenuous. Certainly he has spent more time investigating the corruption endemic in our federal health system than anyone in the history of the New York Times. So at what point do the Fed's junk science, misdemeanors, and perjury before Congress pile up to a tipping point whereby nothing coming our health agencies can be taken at their word?  Robert evidently passed that threshold long before the rest of us. As we witness our federal health officials back pedaling or abandoning their own health advice, rewrite scientific analyses, rapidly fund compromised research institutes in order to debunk the next damning study about the inefficacy of masks, social distancing and the Covid vaccines' adverse effects and mandates, we are observing a health system in dismal disarray. Improvising on a meditation by the Trappist monk Thomas Merton, who had carried on a correspondence with Robert's mother Ethel, Times' journalists such as Nagourney and Rabin are like people who wander the countryside painting billboards that say “The CDC Saves” or “Prepare to Meet God (Anthony Fauci).”  Oddly, these biased opinion essays should not make us think about the CDC nor Fauci. Rather we should wonder what goes on in these writers' minds. Absent any journalist integrity, we should wonder what their motives are to force THEIR CDC and Fauci upon us by way of condemning the critics of the government's failed Covid pandemic policies. Or rather should we pity these journalists' scorn and vitriol as simply pathetic projections of themselves?

In this episode, Social Justice and Sports Medicine Research Specialist, Sheree Bekker, talks about social justice in sports, medicine, and research. Today, Sheree talks about the conversations around physiology and injuries, and the different environments that affect the ACL injury cycle. How do clinicians implement the findings in the research? Hear about Sheree's qualitative research methods, the importance of recognising the social determinants of injuries, tackling systemic experiences, and get Sheree's advice to her younger self, all on today's episode of The Healthy, Wealthy & Smart Podcast.   Key Takeaways “We have to recognise the human at the centre of those experiences.” “Gendered language that seems like everyday language in sport can be really harmful to both men and women.” “[Be] cognisant of, and [be] able to have those conversations with athletes, patients, people that you work with all the time about their social conditions of their lives.” “The social conditions of our lives play into our injuries and our rehabilitation.” “It is about not simply seeing rehab as a biomedical issue alone to solve, but thinking about it as socially, politically, and materially oriented is a practice that you might incorporate in your way of thinking.” “Injury prevention, and a contemporary vision for injury prevention, needs to be athlete-centred and human-focused.” “We need to have those uncomfortable conversations about our complex, messy realities.” “Context is everything.” “Sport isn't neutral. It isn't apolitical.” “We can start to ask these questions, start to have these conversations. The answers aren't going to come tomorrow.” “These ripples will take some time.” “Connection is greater than competition.” “Hold on to the power of connecting with people who are at the same career stage and doing work with people who are at the same career stage as you.”   More about Sheree Bekker Dr Sheree Bekker (she/her) was born in South Africa, grew up in Botswana, completed her PhD in Australia, and now calls Bath (UK) home. She is an expert in ‘complexity' and research that links social justice and (sports) injury prevention. She has a special interest in sex/gender and uses qualitative methods. This underpins her work as an Assistant Professor in Injury Prevention and Safety Promotion in the Department for Health at the University of Bath. At Bath, she is Co-Director of the Centre for Qualitative Research, and a member of the Centre for Health and Injury and Illness Prevention in Sport (CHI2PS), and the Gender and Sexuality Research Group. Internationally, Sheree is an Early Career Representative for the International Society for Qualitative Research in Sport and Exercise, and a founding member of the Qualitative Research in Sports Medicine (QRSMed) special interest group. In 2020 she was appointed as an Associate Editor of the British Journal of Sports Medicine, and in 2021 she was appointed Qualitative Research Editor of BMJ Open Sport and Exercise Medicine. She completed a Prize Research Fellowship in Injury Prevention at the University of Bath from 2018-2020, and received the 2019 British Journal of Sports Medicine Editor's Choice Academy Award for her PhD research.   Suggested Keywords Healthy, Wealthy, Smart, Physiotherapy, Social Justice, Injury, Prevention, Gender, Sexuality, Physiology, Sociology, Environment, Research, Change,   Resources: Anterior cruciate ligament injury: towards a gendered environmental approach   To learn more, follow Sheree at: Website:          https://sites.google.com/view/shereebekker/home Twitter:            @shereebekker Instagram:       @sheree_bekker   Subscribe to Healthy, Wealthy & Smart: Website:                      https://podcast.healthywealthysmart.com Apple Podcasts:          https://podcasts.apple.com/us/podcast/healthy-wealthy-smart/id532717264 Spotify:                        https://open.spotify.com/show/6ELmKwE4mSZXBB8TiQvp73 SoundCloud:               https://soundcloud.com/healthywealthysmart Stitcher:                       https://www.stitcher.com/show/healthy-wealthy-smart iHeart Radio:               https://www.iheart.com/podcast/263-healthy-wealthy-smart-27628927   Read the Full Transcript Here:  00:02 Hi, Sheree, welcome to the podcast. I'm so excited to have you on. I've been looking forward to this for a long time. So thank you so much for joining.   00:12 Thank you for having me. Karen. I am delighted to be talking to you today.   00:16 And today we're going to talk about some of now you had a couple of different presentations at the International Olympic Committee meeting in Monaco a few weeks ago, and we're going to talk about a couple of them. But first, I would love for you to tell the audience a little bit more about you, and about the direction of your research and kind of the why behind it. Because I think that's important.   00:43 Mm hmm. Yeah, I've actually I have been thinking about this a lot recently, over the course of the pandemic, and thinking about where my research and my work is going and why I'm so interested in in kind of social justice issues in sports injury research in Sport and Exercise medicine. And I guess for me, there are two reasons for that both of them related to my background. First of all, I was born in South Africa. And I grew up in Botswana. And I think, you know, growing up into countries that have interesting pasts, you know, South Africa having post of apartheid and Botswana having been a colonized country, I think I grew up in places where we were used to having difficult conversations about social justice issues on a national level. And I think, you know, that is something that has influenced me definitely in the way that I see the world. The second part for me is I studied human movement science at university. And my program was in a Faculty of Humanities and Social Sciences. And I didn't realize at the time that most people get their sport and exercise medicine, sports science, human movement, science training, in medical faculties, or in health faculties, whereas mine was very much social sciences and humanities. And I only realized this later that my training in this regard was quite different in terms of the way that I see the work that we do. And so now, I've landed here at the University of Bath, and I'm in a department for health. But once again, I'm back in a Faculty of Humanities and Social Sciences. So it's been a really, really nice connection for me to come back to these bigger social justice questions, I guess, that I'm interested, you know, in our field. So for me, that's really the why I think of why I do this work.   02:42 And, and kind of carrying along those themes of social justice and really taking a quat. Know, a quantitative, qualitative, sorry, qualitative eye, on athletes and on injury, let's talk about your first talk that you gave it at IOC, which is about the athletes voice. So take us through it. And then we'll ask some questions. So I'll, I'll shoot it over to you.   03:17 Yeah, so um, my first talk, the first symposium that I was involved in at IOC this year, we had titled The athlete's voice, and those of us who were involved with it, we're really proud to be able to get this topic, this kind of conversation onto the agenda in Monaco. I had so many people comment to me afterwards, that this was the first time that we've been able to have this kind of discussion at this specific conference. And, you know, previous editions, I think, have been very much focused on that biomedical that I was just talking about, given that it's Sport and Exercise medicine. And it was the first time that we've been able to bring athlete voice into this space. And so this symposium in my talk in particular, was really focused on qualitative research. Even though when we pitched the symposium, we kind of decided that we couldn't call it qualitative research, because it wouldn't have been accepted at the time. And, and now, it's amazing to me how far we've come that we can actually talk about qualitative research in these spaces. So what I spoke about, and what I was interested in is, you know, what are the kinds of different knowledges and who are the people that we might listen to in Sport and Exercise medicine and sports injury more broadly, that traditionally we maybe haven't scented and haven't listened to? And I was interested in those kinds of social meanings of injury and of injury prevention and how we might do things differently. So you know, for me, it was that Recognizing the value of alternative perspectives, and working across disciplines and advancing our research and practice in this way. And so that's really what I spoke about was, you know how we might do these things differently by actually listening to the people at the center of our work and listening to athletes themselves. And that was really the focus of that symposium.   05:26 And in looking through some of the slides from the symposium, some of the quotes that I'm assuming we're taking from the qualitative work are, gosh, they're kind of heartbreaking. So what do you do with that information once you have it, right? So you're conditioned not to quit, you turn off your emotions, you become a robot as soon as you step onto the field or the pitch or the court. So how do you take that qualitative research? And what do you do with that once you have it?   06:01 Yeah, so you know, my talk, the way I kind of structured my talk was to talk about how we generally do injury prevention. And what we generally do is we, you know, figure out what the issue is what the injury problem is, we develop an intervention, and then we implement that in intervention and hope that it works. And, and some, you know, that's the kind of general cycle that we use. And what I decided to do in my talk, which was only a 10 minute talk was to dedicate two of those minutes to a video that I showed, that was just set to music that flashed up all of these quotes from athletes. And there were quotes that I'd collected from a number of different sports, a number of different athletes and spaces over the years, that really speak about their experience in sports and these toxic environments, which is something that I think we tend to kind of put to the side, maybe sometimes and ignore, sometimes in sport, when we put sport up on a pedestal and only think about the good things that happen in sports. And those quotes are also, I guess, a throwback or connection to one of the other talks that I had at IOC, which is not something that I think we'll speak about today, but about safeguarding and recognizing safeguarding as an injury prevention issue. And so we had these, like two minutes of these quotes from athletes. And I think that video really signaled a palpable shift in the room in recognizing what athletes are actually saying, and what their experiences are in sport about needing to, I guess, you know, put their their kind of robot hat on and be this strong person within sport where they can't break down where they can't have injuries or anything like that. Otherwise, they're going to be the team. And just for us to come back and to recognize that humanity in that experience, within sport, I think is really, really important, especially when we're at a conference where we're talking about injury prevention and interventions, we have to recognize the human at the center of those experiences. And so for me, coming back to your question about what do we do with that information? I think that's really powerful information, in terms of how we think about what injury prevention is, and does. And I guess we always focus on bodies, and you know, body parts, the ankle, the knee, the hip, the growing. You know, that's, that's kind of been a big focus of injury prevention. And I think we often forget that injury prevention is and can be so much more than that. And that there are these social factors, or social determinants, that to play into injury and its prevention. So the social aspects of our lives in terms of, you know, abuse that might happen in these spaces, or just being exposed to toxic spaces, you know, how that does actually render us more susceptible to injury, and how that can thwart our injury prevention efforts in these spaces. So for me, it's about integrating both of those two things I think together, and that's what I'm kind of getting at with qualitative research.   09:19 And, and that leads me into something else I wanted to talk about, and that is a review from the British Journal of Sports Medicine that you co authored with Joanne Parsons and Stephanie Cohen, anterior cruciate ligament injury towards a gendered environmental approach. And what you just said, triggered in me something in in reading through that article was that there's intrinsic factors and extrinsic factors that can lead to injury and injury prevention programs, if done well, should incorporate both of those. Right but they often concentrate on the biomedical part of the The, whether it be strength training, or landing, or, you know, whatever it may be when we look at a lot of these injury prevention programs, but there are so many contextual issues and extrinsic issues that can impact any of those programs. So I'll kind of let you sort of talk through that a little bit and talk through some of the main points that you found in that paper. But gosh, it really gets you thinking like, Well, wait a second, it could be, like you said, if you are, depending on the environment in which you live, can have a huge impact. And it's, it's more than just, especially when it comes to girls and women, it's more than just oh, it's because you have your period. And that's why this happened. Or if your hips are wider, that's why you got injured, right? So go ahead, I'll throw it over to you. And you can kind of talk through that paper a little bit, and then we'll see what comes up.   11:04 Mm hmm. You know, I'm so happy to hear you say that, because I'm so I'm not a clinician, but it has been amazing to me to hear how this paper has resonated with clinicians and people working in this space in terms of your own experiences and what you see and what you hear from the people that you're working with. So yeah, you're absolutely right. I mean, this paper was born out of conversations that Steph and Joanne and I had in terms of how we were frustrated by I guess, the discourse around sports injury, particularly for girls and women, often being blamed on our physiology on our bodies, right. And to us, that seems like a bit of a cop out. And just to say, oh, you know, girls are more susceptible to ACL injury, because they have wider hips, so there's nothing that we can do about it, you know, so that's really pitched us that intrinsic risk factor that girls and women are just inherently weaker, or supposedly more fragile than boys and men, and there's nothing that we can do about it. So we're just going to have to kind of live with those injury breeds. Right. And, and we found that this kind of thinking had really underpins so much of the injury prevention work that we'd seen over the last 10 or 20 years. And we wanted to problematize this a little bit and to think through what those kind of other social and I would say structural determinants of sports injuries are. So I'm starting to talk about this idea of the social determinants of injury. So not just what are those intrinsic things, but actually, what are the what are the other other social modes, I guess, that we might carry that might lead to injury. So in this paper, we speak about how we, as human beings, literally incorporate I think, biologically, the world in which we live. So our societal or ecological circumstances, we incorporate that into our bodies. And so we can start to see how injury might be a biological manifestation of exposure to that kind of social load. So for girls and women, how our gendered experience of the world might render us more susceptible to injury, rather than just positioning ourselves as being more weak, or more fragile. So we were interested in how society makes us and skills in women more weaker, and more fragile. And so in this way, we speak about how you know, from the time that we're babies, girls are not expected to do as much physically we are brought up differently to young boy babies might be when we go through school and play sport in school, we play different kinds of sports, and again, you know, on average, or in general, and girls, goes out, you know, not encouraged to be as active and to do as much with our bodies as boys. And we then go in right to have this kind of that cumulative effect of less exposure to activities and doing things with our bodies. Actually, that is what leads to us being more susceptible to things like ACL injury over time. And this is carried on in the kind of elite sports space as well. So we see how girls and women's sports are devalued in so many ways and how we're not expected to do as much or to perform as well. Or to train as hard I guess, as boys and men So an example of this that actually happened a couple of weeks after we published the paper was the NCAA March Madness. I don't know if you remember, there were those pictures that were tweeted all over social media, about the women's division, only being supplied with one set of teeny, tiny Dunda. Whereas the men's division was given, you know, massive weight room with everything that they needed to be able to train to be able to warm up and do everything that they needed to do in that state. And the first that was just an excellent example of what we're talking about in terms of girls and women being expected to and actually being made, I guess, weaker than boys and men are in exactly the same sports spaces. And so that's kind of a rundown, I guess, of what we wrote about in the paper.   15:53 Yeah, and I look back on my career as I was a high school athlete, college athlete, and not once was it, hey, we should go into the gym and train with specific training programs, because it will help to make you stronger, maybe faster, better, less prone to injury, but the boys were always had a training program. You know, they always had a workout program. So I can concur. That is like a lived experience for me as to what training was like, comparing the boys versus girls college straight through or high school straight through to college. And yes, that March Madness thing was maddening. Pun intended. I couldn't you could not believe couldn't believe what we were seeing there. That was that was completely out of bounds. But what I'd like to dive in a little bit deeper to the article, not not having you go through everything line by line. But let's talk about the different environments that you bring up within the article, because I think they're important. And a little more explanation would be great. So throughout this kind of ACL injury paradigm, you come up with four different environments, the pre sport environment, the training environment, the competition environment, and the treatment environment. So would you like to touch on each of those a little bit? Just to explain to the listeners, how that fits into your, into this paper and into the structure of injury prevention?   17:31 Yeah, sure. So um, yeah, what we did with this paper was we take we take the the traditional ACL injury cycle, and that a lot of us working in sports injury prevention are aware of, and we overlay what we called gendered environmental factors on top of that, so we wanted to take this this site, call and think through how our gendered experiences and girls and women, again render us more susceptible, and over the course of a lifetime, or a Korean. And so starting with the pre sport environment, you know, that goes back to what I was just saying about girls and boys being girls being socialized differently to boys, when we're growing up. So that kind of life course effect, gender affects over the life course, in terms of what we're expected to do with our bodies. That really starts in that pre sport environment when we're babies and young boys and young girls. And then we track how that works throughout the ACL injury cycle. So moving into the next step, coming back to this NCAA example, you know, what the training environment looks like, and how it might be gendered in ways that we might not even pick up on. So another example here, and this is a practical example that we've given to some sports organizations, since then, is, you know, the kind of gendered language that seems like everyday language and sport that can actually be really harmful to both men and women. So for example, you know, talking about girl push ups, you know, that really does set a precedent for what we think about girls and women in sports spaces. When you say, Oh, you go over there and do some girl push ups, it really does render girls and women as being more weak, you know, weaker and more fragile than boys and men. So those kinds of gendered experience in sports spaces, and you're an example there is really key. But then we also talk about kind of during injury and post injury as well. And this comes more into the kind of rehabilitation space and so on how, again, expectations of girls and women's bodies might play into what we expect when we go through rehabilitation as well and, and how that plays into that ACL injury cycle of recovery, as well. So that's really for So it was overlaying gender, across all of those spaces. And I think that gives us a really powerful way of looking at ACL injury differently and to, to conceptualize what we might do both in injury prevention, but also once injury has happened to help girls and women differently.   20:20 And in reading through this paper, and and also going through the slides that you graciously provided on Twitter, of of all of your talks at IOC, as a clinician, it for me, gives me so much more to think about, and really sparked some thoughts in my head as to conversations to have with the patient. So what advice would you give to clinicians, when it comes to synthesizing a lot of this work? And taking it into the clinic, talking with their patient in front of them and then implementing it? Because some people may say, oh, my gosh, I have so much to do. Now, I have to read all of this. Now I have to incorporate this, do you know what I mean? So it can some be somewhat overwhelming. So what advice do you have for clinicians? Yes,   21:13 so I really do think and as I said earlier, I think a lot of what we're seeing here is what clinicians are doing all the time anyway, I think, especially people who are already connected to this kind of idea of this social determinants of health. And so I guess, for me, it is really just being cognizant of, and being able to have those conversations with athletes, with patients with people that you work with all the time, about their social conditions of their lives. So not again, not just reducing people down to bodies, but recognizing that people have you know, that the social conditions of our lives play into our injuries and our rehabilitation, and holding space for that, you know, when I'm teaching, that's what I say to my students all the time, but I know that that you know, this, and clinicians know this better than I do. You, you know, it's not just about saying to someone, go away and do these exercises, and come back to me when you know, that person might have a full time job with three kids to look after. And, you know, a lot of other things on their plate as well that that one exercise or exercise program isn't necessarily going to be the silver bullet or the answer to, you know, the way that they need to be dealing with that injury. So I think for me, it's again, that re humanizing and being able to have those those conversations and recognizing those social determinants of injury or recovery, and so on. And so I think for clinicians, it is about not simply seeing rehab as a biomedical issue alone to solve, but thinking about it as socially and politically and materially oriented as a practice that you might incorporate in your way of thinking. That's really it. It doesn't need to be any more than that. We don't need to complicate it. Any more than that.   23:10 Yeah. Perfect. Thank you for that. And as we start to wrap things up, is there a, are there any kind of key points that you want to leave the listeners with? Or is there anything that we didn't touch on that you were like, oh, I need I need people to know this. This is really important. Hmm.   23:36 Yeah, I think, you know, if we kind of connect the conversations that we've kind of had today with the different points that we've connected to, I think, you know, what I saw in IRC at the IOC conference in Monaco is I really felt especially on day one at that athlete centered symposium that we had, I really felt like a palpable shift in that room. And in the conversations that I've had afterwards, with people I've had so many people come up to me to say that, you know, that it was really inspiring, and it's helped them to be able to go away and have different kinds of conversations, incredibly have different kinds of conversations about the work that we're doing in injury prevention and in Sport and Exercise medicine more broadly. And so I really think that we need to focus on that idea that injury prevention and a contemporary vision for injury prevention needs to be athlete centered and human focused. And I think if we truly committed to this, I think the ways in which we develop our interventions, and the ways in which we might go about our work, more generally in Sport and Exercise medicine, in physiotherapy and so on, it needs to reflect the socio cultural, so meaning those social determinants of injury in cluding the ways in which things like sexism, and misogyny, and racism, and classism, and ableism, and homophobia and transphobia, how that all can and does actually lead to injury. I think those are larger conversations that we need to be having enough field that we've started to have very slowly, but they are difficult conversations to have. And we often cut them out when we only think about injury as a biomedical thing, again, only thinking about bodies. And so for me, I think those are the those are the thing that we now need to get uncomfortable, you know, about, we need to have those uncomfortable conversations about our complex, messy realities, and that we're dealing with that athletes are human beings, that these are our experiences of the world, that sport and exercise medicine needs to reflect that as well. In terms of our composition, we need to reflect the communities that we serve as well. And Tracy Blake talks about that often. And you know, those are the conversations that I'd like to see our field having going forward. And I do think there was a shift in being able to say those things at Monaco this year.   26:16 Yeah. And so what I'm hearing is, was the big takeaway for me from Monaco is context is everything. And we can't, we can no longer take that out. And focus, like you said, just on the biomedical aspect of this person in front of us as if they don't have past experiences and emotions and thoughts and fears and concerns. And context is everything. And for clinicians, it sounds like a challenge to start having these conversations at more conferences. I know it's this little kind of bubble of clinicians, but if it can start there, perhaps it can make a ripple out into the wider public and into having these conversations with your athletes and patients and not be afraid to have these difficult conversations, or to ask the probing questions to the person in front of you. Because they're more than just their ACL injury, they're more than just their back pain. So I think challenging clinicians to have these conversations, whether it be one on one like this, or within large groups at conferences, and then take that back to your, to your practice and really start living it and understanding that this can is as important, maybe, in some cases more important than the biomedical injury in front of you.   27:41 Oh, I could not agree more with that statement. I mean, something that I've spoken about a lot before is that, you know, sport isn't neutral. It's not a political. And it's the same for the work that we do. It's, you know, for far too long, it's been positioned as a neutral science thing that we do. And I think we're now starting to recognize the context around that, that our values and our principles and people's lives and experiences, you know, as you say, play as much as if not more of a role in their experience of sport, and injury, and rehab, and all of that. So I would agree with you completely, we need to be having more of these conversations, we need to recognize this within our research, we need to recognize this within our practice. And we can't keep going on as if you know, none of so if we can remove all of that from the practice of working with human beings and being human beings as well. You know, all of this is connected for me. And as you know, as we're seeing now, it's for all of us who work in this space, once we start to have these conversations, we can start to ask different questions, we can start to think about things differently. And I think that that's really powerful for the future of our work in this space.   28:55 Yeah. And I think it's also important to remember that we can start to ask these questions start to have these conversations that the answers aren't going to come tomorrow. So that instant gratification that has become the world that we are now living in that if it doesn't happen within the next couple of days, that means it's not going to happen, but that these ripples will take some time. Yeah, absolutely.   29:19 And, you know, so a lot of my work is in complexity theory. And what I say about that is, you know, there probably are not going to be hard and fast answers here. But it will bring up new considerations and it will bring up I think, I'd like us to move away from this idea that we can solve things, but actually move closer towards the idea that this is an ongoing practice. And that that's always going to be I think, more powerful for me when we see things like injury prevention as a process or a practice. That's not necessarily going to solve things. But that is you know, really To the context in which we live in our lives is an ongoing thing. And I think that's what we brought into the ACL injury cycle. Papers. Well,   30:09 yeah, I think it takes away from the clinician as being the MS or Mr. Fix it to, okay, we are layering ourselves into people's lives. And we need to be able to do that in a way that fits the person in front of us as best we can.   30:26 Yeah, exactly. Beautifully said exactly. We can't necessarily solve those things for them. But these provide considerations, things that we can do. And yeah, we can move with that.   30:39 Yeah, absolutely. Well, Cherie, thank you so much. I mean, we can go on and talk for days on end about this stuff. And perhaps when one of these days we will we'll have a bigger, wider, broader conversation and and make it go on for a couple of hours, because I'm sure it will bring up a lot of questions, maybe some answers, and perhaps some changing of minds when it comes to injury prevention and what our role is as clinicians. So thank you so much, where can people find you?   31:13 Thank you, Karen. And I love that I think broader conversations are so helpful in this space. So people can find me on Twitter at Shree Becker, that's probably the best place to find me. I'm always over there and happy to have broader conversations with everybody. So please come and find me on Twitter.   31:32 Perfect. And we'll have links to everything, including the paper that we're talking about. From BDSM. We'll have links to everything at the show notes at podcast dot healthy, wealthy, smart, calm. So one question left that I asked everyone and that is knowing where you are now in your life and in your career? What advice would you give to your younger self?   31:51 Oh, so that's a really good question. And it's I think it's my Elan series, again, connected to what we saw in Monaco. And something that I've said for many years now is connection is greater than competition. And something that I live in that I feel like I wish I had done earlier is to hold on to the power of connecting with people who are at the same career stage and doing work with people who are at the same career stages as you especially someone who has and is an emerging researcher, or researcher clinician in this space, because I think the exciting new conversations that we're seeing in this space are coming from people who are you know, recently merging, I guess, in these researchers faces and so it's okay to collaborate rather than being in competition with people who are doing great work in your area. So that would be my advice.   32:54 I love it. I love it and couldn't agree more. So Sheree, thank you so much for coming on. Thank you again. I appreciate it.   33:02 Thank you so much, Karen. And everyone. Thanks   33:04 so much for tuning in and listening and have a great couple of days and stay healthy, wealthy and smart.

In this network meta-analysis, as compared to normothermia (37–37.8 °C), we found that deep hypothermia (31–32 °C), moderate hypothermia (33–34 °C) and mild hypothermia (35–36 °C) may have no effect on survival and functional outcome among comatose survivors of out-of-hospital cardiac arrest. However, both deep and moderate hypothermia were associated with an increased risk of arrhythmia compared to normothermia. Original paper: https://doi.org/10.1007/s00134-021-06505-z (Targeted temperature management following out-of-hospital cardiac arrest: a systematic review and network meta-analysis of temperature targets) Speakers: Claudio SANDRONI. Institute of Anesthesiology and Intensive Care Medicine, Università Cattolica del Sacro Cuore, Rome (IT) and Department of Intensive Care, Emergency Medicine and Anesthesiology, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Rome (IT). Associate Editor of the ICM Journal. Jerry P. NOLAN. Department of Anaesthesia and Intensive Care Medicine, Royal United Hospital, Bath (UK) and Warwick Clinical Trials Unit, University of Warwick, Coventry (UK). Shannon M. FERNANDO. Division of Critical Care, Department of Medicine, and Department of Emergency Medicine, University of Ottawa, Ottawa, ON (CA).

CRAIG LAURITSEN is this weeks 'Engine Room' Guest. A few of Craig's performance highlights include: Brian Ferry support at the Adelaide Festival Theatre in 1988. Supporting artist for Kate Ceberano and Wilbur Wilde at the Club Foote in 1989, 3 months, 70 plus performances in New Delhi, India in 1994, 10 months, 80 plus performances with various Blues and Jazz bands in USA in 1994 -1995, the inaugural Singapore Blues Festival in 1996, and performing the soundtrack to 'The Tracker' (film by internationally renowned film maker Rolf de Heer) live with Archie Roach at the Adelaide Festival and the Melbourne Film Festival in 2002. EDUCATION: Cert. in Commercial Music at Kingston TAFE in 1986. Diploma in performing Arts (Jazz) at Adelaide University 1987 - 1989. Studied with Pandit Debashish Chakraborty in New Delhi in 1994. Studied with Bob Moses in Boston 1994 -1995. Individual lessons with Victor Lewis, Jim Pease, Grant Collins, Mike Clark. DRUM EDUCATOR: Private drum tutor from 1983 to present, and has taught at Gordon Lasalle Music, Boston USA; Rock Music, Adelaide; AIMMS, Adelaide, as well as various college's in SA. CYMBALSMITHING: Began modifying cymbals in 2005, Importer of Turkish cymbals since 2006, and Worldwide exporter of Craig Lauritsen Custom Cymbals since 2007. Travelled to Italy to meet master cymbal smith Roberto Spizzichino in March 2008, and during that same trip met cymbal smiths Michael Paiste in Switzerland, Steve Hubback in London and Matt Nolan in Bath (UK). Has made cymbals for drummers all over the world including, Jack DeJohnette, Gregory Hutchinson, Luke Flowers, Jochen Rueckert, Adam Cruz, Hamish Stuart, Darryn Farrugia, Michael Iveson, and many more. AUTHOR: has written 8 instructional drum method books which are published and internationally distributed by LTP Publications. Titles include Drum Method, Drum Grooves, 1000000 Drum Grooves, Rhythm Section Method for Bass and Drums, Rhythm Section Grooves for Bass and Drums, Blues Drumming, Country Drumming, Complete Learn to Play Drums Manual. Recording Highlights: 'The Eureka Suite' (1999) featuring Eric Bogle and John Schumann, Peter Gelling's ARIA nominated (2000) CD 'Bluestime', 'The Tracker' soundtrack which won the following awards: ARIA nomination for best soundtrack album (2002). IFM award for best soundtrack (2002). Film Critics Circle award for best soundtrack (2002), and 2 APRA/AGSC awards for best song in a cinema feature. Peter Gelling's Musicoz Blues Award winning (2003) CD 'Fortune', Eric Bogle's ‘Other People's Children' (2005), and Kubrick self-titled album (2006). Kubrick ‘Think' (2007). Music: "Band It About" theme song, written and recorded by Catherine Lambert & Michael Bryant. Outro: “Cultural Fatigue” from Craig's album “Monachopsis”, released April 29, 2016: https://craiglauritsen.bandcamp.com/album/monachopsis Craig's links: http://www.cymbalutopia.com/ https://www.youtube.com/c/CraigLauritsen https://www.instagram.com/cymbalutopia/?hl=en To support this independent podcast: https://paypal.me/banditabout?locale.x=en_AU If you enjoyed listening please share the link with your friends. Contact Band It About: banditabout17@gmail.com Follow on Facebook: https://www.facebook.com/BAND-It-ABOUT-Podcast-Series-103410885324059/ Review: https://www.podchaser.com/podcasts/band-it-about-podcast-series-985443/reviews/63027 #drummers --- Send in a voice message: https://anchor.fm/dianne-spillane/message

They forced me into this tiny little interrogation room off the big anteroom, a whole mob of policemen shouting and screaming. I thought I would perish there, that I was going to die there and then, which was exactly what they wanted me to think. Their intention was to overwhelm me with terror, and they did. But then Swanepoel's interrogation partner, a man named Harvey Richter, produced this brick and he held it up in front of me right across my eyes and I thought, looking at its granular surface, that it would abrade my face when he hit me with it. But he didn't, he put it down in front of me and said: Stand on it.    Episode Description: John begins our journey through his past by describing his family life before his arrest and torture at the age of 21 at the hands of the South African Security Police. We learn of his family's longstanding history of opposition to political injustice. He then recounts his methods of survival during his imprisonment which included forming a 'relationship' with the brick he was forced to stand on for days and nights. He also internally relied upon his loving parents, his girlfriend, his Jewish identity, and The Sounds of Silence. He was held in solitary confinement and brutalized until his release to travel to Israel.  After establishing his life in England, John eventually began training as a psychotherapist. He describes having life-changing personal treatments including two analyses and he has become a contributor to the field especially to the world of analytic group therapy. He shares with us vignettes of patients he has worked with and how he has turned 'swords into plowshares' in his efforts at transforming his own scars into the act of healing others.    Our Guest: John Schlapobersky, BA MSc is a psychoanalytic and couple psychotherapist and a group analyst accredited by the United Kingdom Council for Psychotherapy. After many years in private practice at the Group Analytic Practice, he established his own Bloomsbury Psychotherapy Practice in 2009. He is also a training analyst and faculty member at the Institute of Group Analysis and an honorary research fellow at the Birkbeck College University of London. He has served as faculty at the London Centre for Psychotherapy, Tavistock Centre for Couple Relationships (TCCR) and is a founding member of the British Society for Couple Psychotherapists and Counsellors. He teaches internationally on topics that include group studies, psychoanalytic and relational theory, and trauma. His commitments include programs in Australia, China, Denmark, Germany, Israel, Japan, Poland, Russia, South Africa, Sweden, Switzerland, the USA, and elsewhere. He was Program Chair for the Group Analytic Society Symposium in 2011: Cultures, Conflict, and Creativity. John was formerly a Consultant Psychotherapist for the Traumatic Stress Clinic, London, and The Medical Foundation for Victims of Torture which, as a founding trustee, he helped establish in 1985. It is now called Freedom From Torture, a leading human rights charity.    Recommended Readings:  Bernstein, H. (1994) The Rift: The Exile Experience of South Africans. London: Jonathan Cape. Reissued Persephone Books, Bath UK, 2020.  Pines, M. (1998) Circular Reflections: Selected Papers in Psychoanalysis and Group Analysis. Jessica Kingsley, London.  Rosenthal, N. (2014) The Gift of Adversity. New York: Jeremy P. Tarcher/Penguin.  Sachs, Albie. (1969) The Jail Diary of Albie Sachs. London: Sphere. Reissued Africa Book Centre, London, 1978.  Sachs, Albie (1990) The Soft Vengeance of a Freedom Fighter. Oakland: University of California Press. Reissued Souvenir Press, 2014.  Schlapobersky, J. (2016) From The Couch To The Circle: Group-Analytic Psychotherapy In Practice. Routledge, London.  Schlapobersky, John R.(2021) When They Came For Me: The Hidden Diary Of An Apartheid Prisoner. Berghan Books, Oxford and New York. 

When stressed, people are quicker to jump to the worst conclusion University College London, July 29, 2021 When under stress, people reach undesirable conclusions based on weaker evidence than when they are relaxed, finds a new study led by UCL researchers. The findings, published today in the Journal of Neuroscience, show that stress can make people more likely to conclude the worst scenario is true. Senior author Professor Tali Sharot (UCL Psychology & Language Sciences and Max Planck UCL Centre for Computational Psychiatry and Ageing Research) said: "Many of the most significant choices you will make, from financial decisions to medical and professional ones, will happen while you feel stressed. Often these decisions require you to first gather information and weigh the evidence. For example, you may consult multiple physicians before deciding on a best course of medical treatment. We wanted to find out: does feeling stressed change how you process and use the information you gather? "Our research suggests that under stress, people weight each piece of evidence that supports undesirable conclusions more than when they are relaxed. In contrast, how they weigh evidence that supports desirable conclusions is not affected by stress. As a result, people are more likely to conclude the worst is true when they are stressed." For the study, 91 volunteers played a categorisation game, in which they could gather as much evidence as they wanted to decide whether they were in a desirable environment (which was associated with rewards) or an undesirable environment (which was associated with losses). They were incentivised for accuracy. Prior to playing the game, 40 of the volunteers were told that they had to give a surprise public speech, which would be judged by a panel of experts. This caused them to feel stressed and anxious. The researchers found that under stress, the volunteers needed weaker evidence to reach the conclusion that they were in the undesirable environment. By contrast, stress did not change the strength of the evidence needed to reach the conclusion that they were in the desirable environment. Lead author, PhD student Laura Globig (UCL Psychology & Language Sciences and Max Planck UCL Centre for Computational Psychiatry and Ageing Research) said that "we usually think of stressful situations as a hindrance to our decision-making process. But the pattern of learning we have uncovered may counterintuitively be adaptive, because negative beliefs may drive people to be extra cautious when in threatening environments."   Thai Cabinet Approves Use of Fah Talai Jone (green chiretta) to Treat Asymptomatic COVID-19 Cases Bangkok Post, July 22, 2021 Prime Minister Prayut Chan-o-cha has instructed authorities to set up a committee to study the use of green chiretta (Andrographis paniculata) extracts to treat Covid-19 patients with mild symptoms. The announcement was made at a cabinet meeting on Tuesday, which was convened to discuss additional measures to help curb the Covid-19 outbreak, the premier said on Wednesday. Deputy Prime Minister and Public Health Minister Anutin Charnvirakul was appointed head of the committee. It will coordinate studies on the safety and efficacy of green chiretta extracts on Covid-19 patients, as well as draft a strategic plan to promote Thai traditional medicine in general. The decision was taken in response to a proposal from Justice Minister Somsak Thepsutin, who urged the government to scale up the use of traditional medicines on Covid-19 patients with mild symptoms. This comes amid a vaccine shortage which has led to criticism for the government. His proposal came with evidence showing the Department of Corrections' success in treating 12,376 inmates who were infected with Covid-19 with green chiretta extracts. Of this number, 5,045 inmates were in Chiang Mai Central Prison, 2,100 in Nonthaburi Provincial Prison and 5,231 in Bang Kwang Central Prison also in Nonthaburi, said Mr Somsak. Before prescribing the herbal medicine to infected inmates, Mr Somsak said he had studied information by the Department of Thai Traditional and Alternative Medicine, which recommended a dosage of 180mg of andrographolides from green chiretta for five consecutive days to patients with mild symptoms. Citing the same research, the minister said each rai of land can yield up to 600kg of green chirettas, which can be turned into roughly 375,000 herbal extract capsules, he said. A total of 3.1 billion such capsules will be needed to cover all Thais, which means 8,400 rai of land will need to be planted with the herb, he said. The Department of Corrections now plans to produce about 50 million capsules of the herbal medicine in the next four months, which it aims to prescribe to about 50% of the prison population, he said. Due to its medical benefits, green chiretta has become a cash crop which is now in high demand in the export sector, he said. Mr Somsak added that the medicinal herb costs about 450 baht per kg    Taking breaks while learning improves memory   Max Planck Institute of Neurobiology (Germany), July 29, 2021 We remember things longer if we take breaks during learning, referred to as the spacing effect. Scientists at the Max Planck Institute of Neurobiology gained deeper insight into the neuronal basis for this phenomenon in mice. With longer intervals between learning repetitions, mice reuse more of the same neurons as before—instead of activating different ones. Possibly, this allows the neuronal connections to strengthen with each learning event, such that knowledge is stored for a longer time. Many of us have experienced the following: the day before an exam, we try to cram a huge amount of information into our brain. But just as quickly as we acquired it, the knowledge we have painstakingly gained is gone again. The good news is that we can counteract this forgetting. With expanded time intervals between individual learning events, we retain the knowledge for a longer time. But what happens in the brain during the spacing effect, and why is taking breaks so beneficial for our memory? It is generally thought that during learning, neurons are activated and form new connections. In this way, the learned knowledge is stored and can be retrieved by reactivating the same set of neurons. However, we still know very little about how pauses positively influence this process—even though the spacing effect was described more than a century ago and occurs in almost all animals. Learning in a maze Annet Glas and Pieter Goltstein, neurobiologists in the team of Mark Hübener and Tobias Bonhoeffer, investigated this phenomenon in mice. To do this, the animals had to remember the position of a hidden chocolate piece in a maze. On three consecutive opportunities, they were allowed to explore the maze and find their reward—including pauses of varying lengths. "Mice that were trained with the longer intervals between learning phases were not able to remember the position of the chocolate as quickly," explains Annet Glas. "But on the next day, the longer the pauses, the better was the mice's memory." During the maze test, the researchers additionally measured the activity of neurons in the prefrontal cortex. This brain region is of particular interest for learning processes, as it is known for its role in complex thinking tasks. Accordingly, the scientists showed that inactivation of the prefrontal cortex impaired the mice's performance in the maze. "If three learning phases follow each other very quickly, we intuitively expected the same neurons to be activated," Pieter Goltstein says. "After all, it is the same experiment with the same information. However, after a long break, it would be conceivable that the brain interprets the following learning phase as a new event and processes it with different neurons." However, the researchers found exactly the opposite when they compared the neuronal activity during different learning phases. After short pauses, the activation pattern in the brain fluctuated more than compared to long pauses: In fast successive learning phases, the mice activated mostly different neurons. When taking longer breaks, the same neurons active during the first learning phase were used again later. Memory benefits from longer breaks Reactivating the same neurons could allow the brain to strengthen the connections between these cells in each learning phase—there is no need to start from scratch and establish the contacts first. "That's why we believe that memory benefits from longer breaks," says Pieter Goltstein. Thus, after more than a century, the study provides the first insights into the neuronal processes that explain the positive effect of learning breaks. With spaced learning, we may reach our goal more slowly, but we benefit from our knowledge for much longer. Hopefully, we won't have forgotten this by the time we take our next exam!     The flavonoid epicatechin inhibits progressive tau pathology in Alzheimer's University of Bath (UK), July 23, 2021 According to news reporting originating in Avon, United Kingdom, by NewsRx journalists, research stated, “Aggregation of the microtubule-associated protein tau into paired helical filaments (PHFs) and neurofibrillary tangles is a defining characteristic of Alzheimer's Disease. Various plant polyphenols disrupt tau aggregation in vitro but display poor bioavailability and low potency, challenging their therapeutic translation.”  Green tea, cocoa, blackberries and blueberries are high in epicatechin. The news reporters obtained a quote from the research from the University of Bath, “We previously reported that oral administration of the flavonoid (-)-epicatechin (EC) reduced Amyloid-beta (A beta) plaque pathology in APP/PS1 transgenic mice. Here, we investigated whether EC impacts on tau pathology, independent of actions on A beta, using rTg4510 mice expressing P301L mutant tau. 4 and 6.5 months old rTg4510 mice received EC (similar to 18 mg/day) or vehicle (ethanol) via drinking water for 21 days and the levels of total and phosphorylated tau were assessed. At 4 months, tau appeared as two bands of similar to 55 kDa, phosphorylated at Ser262 and Ser396 and was unaffected by exposure to EC. At 6.5 months an additional higher molecular weight form of tau was detected at similar to 64 kDa which was phosphorylated at Ser262, Ser396 and additionally at the AT8 sites, indicative of the presence of PHFs. EC consumption reduced the levels of the similar to 64 kDa tau species and inhibited phosphorylation at Ser262 and AT8 phosphoepitopes. Regulation of the key tau kinase glycogen synthase kinase 3 beta (GSK3 beta) by phosphorylation at Ser9 was not altered by exposure to EC in mice or primary neurons. Furthermore, EC did not significantly inhibit GSK3 beta activity at physiologically-relevant concentrations in a cell free assay.” According to the news reporters, the research concluded: “Therefore, a 21-day intervention with EC inhibits or reverses the development of tau pathology in rTg4510 mice independently of direct inhibition of GSK3 beta.”     Fruit compound may have potential to prevent and treat Parkinson's disease   Johns Hopkins University, July 29, 2021 Johns Hopkins Medicine researchers say they have added to evidence that the compound farnesol, found naturally in herbs, and berries and other fruits, prevents and reverses brain damage linked to Parkinson's disease in mouse studies. he compound, used in flavorings and perfume-making, can prevent the loss of neurons that produce dopamine in the brains of mice by deactivating PARIS, a key proteininvolved in the disease's progression. Loss of such neurons affects movement and cognition, leading to hallmark symptoms of Parkinson's disease such as tremors, muscle rigidity, confusion and dementia. Farnesol's ability to block PARIS, say the researchers, could guide development of new Parkinson's disease interventions that specifically target this protein. "Our experiments showed that farnesol both significantly prevented the loss of dopamine neurons and reversed behavioral deficits in mice, indicating its promise as a potential drug treatment to prevent Parkinson's disease," says Ted Dawson, M.D., Ph.D., director of the Johns Hopkins Institute for Cell Engineering and professor of neurology at the Johns Hopkins University School of Medicine. Results of the new study, published July 28, in Science Translational Medicine, detail how the researchers identified farnesol's potential by screening a large library of drugs to find those that inhibited PARIS. In the brains of people with Parkinson's disease, a buildup of PARIS slows down the manufacture of the protective protein PGC-1alpha. The protein shields brain cells from damaging reactive oxygen molecules that accumulate in the brain. Without PGC-1alpha, dopamine neurons die off, leading to the cognitive and physical changes associated with Parkinson's disease. To study whether farnesol could protect brains from the effects of PARIS accumulation, the researchers fed mice either a farnesol-supplemented diet or a regular mouse diet for one week. Then, the researchers administered pre-formed fibrils of the protein alpha-synuclein, which is associated with the effects of Parkinson's disease in the brain. The researchers found that the mice fed the farnesol diet performed better on a strength and coordination test designed to detect advancement of Parkinson's disease symptoms. On average, the mice performed 100% better than mice injected with alpha-synuclein, but fed a regular diet. When the researchers later studied brain tissue of mice in the two groups, they found that the mice fed a farnesol-supplemented diet had twice as many healthy dopamine neurons than mice not fed the farnesol-enriched diet. The farnesol-fed mice also had approximately 55% more of the protective protein PGC-1alpha in their brains than the untreated mice. In chemical experiments, the researchers confirmed that farnesol binds to PARIS, changing the protein's shape so that it can no longer interfere with PGC-1alpha production. While farnesol is naturally produced, synthetic versions are used in commerce, and the amounts people get through diet is unclear. The researchers caution that safe doses of farnesol for humans have not yet been determined, and that only carefully controlled clinical trials can do so. Though more research is needed, Dawson and his team hope farnesol can someday be used to create treatments that prevent or reverse brain damage caused by Parkinson's disease.   Plant compounds reveal anticancer mechanisms Russian Academy of Sciences, July 28 2021.  Research published on June 9, 2021 in Scientific Reportsexplored mechanisms involved in the cancer protective effects of 30 compounds derived from fruits and vegetables. The researchers hope that their findings will contribute to the formulation of new drugs that will have fewer side effects than drugs currently in use.   “To create potent new drugs that will target only the tumor, it was necessary to determine how dietary compounds affect cell proteins in the prevention and treatment of cancer,” explained coauthor Grigory Zyryanov, who is a professor at the Russian Academy of Sciences. “Therefore, by modeling molecular mechanisms, we figured out how substances bind to proteins. This allowed us to determine the pool of therapeutic targets that the drugs will subsequently target. For example, these are anti-apoptotic (prevent apoptosis) and pro-apoptotic (induce apoptosis) proteins, protein kinases, and others. But a key drug target is phosphatidylinositol-3-kinase . . . This enzyme influences mutations in cancer, rearrangement, and amplification of genes.” Compounds investigated in the study included emodin, eugenol, gingerol, sulforaphane, linalool, catechin, oleanolic acid, ursolic acid, curcumin, yakuchinone-A, pinusolide, alpha-boswellic acid, oleandrin, sesquiterpene lactone-326, resveratrol, triterpenoid, beta-boswellic acid, anethole, capsaicin, glycolic acid, quercetin, genistein, ellagic acid, flavopiridol, zerumbone, garcinol, guggulsterone, parthenolide, halogenated monoterpenes and silibinin. Of these compounds, silibinin, flavopiridol, oleandrin, ursolic acid, alpha-boswellic acid, beta-boswellic acid, triterpenoid, guggulsterone and oleanolic acid had the greatest binding affinity with phosphatidylinositol-3-kinase alpha (P13K), which is involved in functions that can contribute to cancer. Other targets identified as binding with various compounds included PKC-η, Ras and H-Ras.  “We assumed that the foods we selected for the study had anti-cancer properties, but this needed to be verified,” Dr Zyryanov noted. “As a result, we found out that diseased cells stop development under the influence of certain combinations of food compounds.”     Meta-analysis supports potential of omega-3s for ADHD Kings College London, July 31, 2021 Omega-3s fatty acid supplements may improve symptoms and cognitive performance in children and adolescents with attention deficit hyperactivity disorder (ADHD), according to a meta-analysis of gold standard clinical trials. Data from seven clinical trials involving over 500 children and adolescents indicated that omega-3s were associated with improvements in clinical symptoms of ADHD, while data from three clinical trials involving over 200 children and adolescents indicated a positive impact on cognitive measures associated with attention. “[W]e provide strong evidence supporting a role for n3-PUFAs deficiency in ADHD, and for advocating n-3 PUFAs supplementation as a clinically relevant intervention in this group, especially if guided by a biomarker-based personalization approach,” wrote the authors, led by Jane Pei-Chen Chang from King's College London, in Neuropsychopharmacology . Boosting EPA/DHA intakes Commenting independently on the meta-analysis, Harry Rice, PhD, VP of regulatory & scientific affairs for the Global Organization for EPA and DHA Omega-3s (GOED): “In the past, I've been lukewarm on whether or not increasing EPA/DHA intake benefits children with ADHD. Results from this meta-analysis put me a little closer to believing. “Minimally, given the low side effect profile of omega-3s versus the drugs of choice to treat ADHD, I would highly recommend first increasing intake of EPA/DHA. This is particularly true if a child doesn't eat at least two servings of fatty fish a week or doesn't take an omega-3 supplement on a regular basis.” Meta-analysis details The new meta-analysis was performed using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines and used established scientific literature databases to identify appropriate studies for inclusion. Data from seven randomized controlled trials (RCTs) with 534 young people indicated that that omega-s3 supplementation significantly improved inattention and hyperactivity symptoms, according to parental reports. Additional analysis revealed that the improvements in hyperactivity were only observed when doses of EPA (eicosapentaenoic acid) of 500 mg/day or more were used. Interesting, the researchers did not find improvements in hyperactivity and inattention when they looked at teacher's reports, unlike what was reported by parents. Omega-3 supplements were associated with improvements in select measures of cognitive performance, said the researchers. “N-3 PUFAs are crucial for optimal neurotransmitter function: for example, incorporating more EPA and DHA in the cell membrane can increase cholesterol efflux, modulate lipid raft clustering and disruption, and affect the function of the dopamine transporter (DAT), which in turn may affect attention and executive function by regulating synaptic dopamine levels,” wrote the researchers. Omega-3 levels Data from case-control studies were also collected to assess if omega-3 levels were also associated with ADHD, with results indicating that children and adolescents with ADHD had lower levels of EPA, DHA (docosahexaenoic acid),and total omega-3s. “In the context of ‘personalised medicine', it is tempting to speculate that a subpopulation of youth with ADHD and with low levels of n-3 PUFAs may respond better to n-3 PUFAs supplementation, but there are no studies to date attempting this stratification approach,” wrote the researchers. “However, we have [previously] shown that individuals at genetic risk of developing depression in the context of the immune challenge, interferon-alpha (IFN-alpha), have lower levels of RBCs n3-PUFAs, and that n-3 PUFAs supplementation prevents the onset of IFN-alpha-induced depression, arguably by replenishing the endogenously low anti-inflammatory PUFAs in the ‘at risk' individuals.”

The topic will cover various generation of energy networks for buildings and outline the concept of Scandinavian ambient loop network, utilising waste heat as a resource for providing its energy need. The concept has a deep connection with wellbeing as it mitigates the need of burning fossil fuel and also absorbs low streams of heat which otherwise would be lost into the atmosphere creating urban height island effect. I will conclude the presentation with a short case study. Under Kartik's leadership, the Sweco building sustainability team has have delivered some of the most significant sustainable buildings in the UK and hence allocated three times BREEAM Company of the year (2014/2016/2017). Specialising in the sustainable design of the built environment, Kartik has over 16 years of experience in commercial, retail, industrial, military, educational and residential developments for new and refurbishment works. Kartik plays key roles in prestigious projects, developing energy strategies that evaluate solutions relative to cost, logistics, energy and carbon reductions, green rating certifications, savings and payback time for new and existing master plans and buildings. He actively pursues innovative thinking in projects to achieve the highest sustainable performance: some of this thinking results in early design guides for architects as well as research and testing in practice. His involvement in academia through lecturing at the University of Bath (UK) provides another platform for him to develop new ideas and obtain insights to define practical, sustainable solutions for buildings further.

This Fall Great Pumpkin LumiNights will take place at Wild Adventures Theme Park in Valdosta, Georgia. 2021 has proved to be the park's biggest opening season yet, and with its success, park officials have decided to add the new Halloween event. Great Pumpkin LumiNights will feature "larger-than-life" pumpkin sculptures throughout the park. The event has already been implemented in the company's sister theme parks - including Dollywood. The family-friendly experience is a $700,000 investment for the park.On June 30th, Mary Shelley's House of Frankenstein in Bath (UK) will open to the public. This interactive experience/museum is bursting with unusual artifacts and vintage items, multi-sensory environments, and assorted body parts. Guests will step into the dark world of Mary Shelley to learn about her tragic life and come face-to-face with an 8-foot recreation of the literary monster that continues to fascinate the world. After the popularity of their Christmas projection show on the Armoury building in Chatham (Ontario, Canada), The Armoury in Lights event organizers have decided to add a Halloween show for 2021. The Halloween event will take place October 14th - 30th with three shows each night. Each show will be 90 minutes - twice as long as their 2020 shows - and feature projections, dancing, and performances. Last year the event switched to a drive-in format and it will remain that way for 2021 - and new for this year is an illuminated entryway featuring works from 10 artists. Applications for performers and artists will be available soon.In the market to buy a haunted house? Waco Haunted House in Central Texas is for sale by co-owners John & Danea Anderson. After 30 years of operation, the Andersons hope to sell it to a new generation of haunters. The sale price will likely be around $600,000 and will include 2 haunted houses (over 7,000 sq. ft. per house), a 60' mobile home/office, store & warehouse, ticket booth tower & concession building, company van, 3 hearses, storage trailers, and more. If the right purchaser comes along, the haunt can be up and running again for the 2021 season.The house of home haunter Kit Espada (East Providence, Rhode Island) was damaged in a fire this past week. Espada hosts an annual Halloween display in her yard, collecting donations and non-perishable food items for the Rhode Island Community Food Bank Association. Some of the homemade props stored in her garage went up in flames, but luckily no one was harmed in the fire. Espada had planned a clown theme for her 2021 display, but with many of her props damaged or lost in the fire, she is doubtful it will happen. A GoFundMe has been set-up for the Estrada family by members of the haunt community.Descanso Gardens in La Cañada, CA announced the return of Carved for this October. The Halloween event features a mile-long trail lined with thousands of professionally-carved, jack-o-lanterns and sculptures made of natural materials. Other activities include pumpkin carving demonstrations, a hay maze, themed food, and a house made of pumpkins. Tickets for this 3-week event will go on sale in September for members and October for the general public.As we prepare for the haunt season, scareactors may want to strengthen their skills for dealing with aggressive guests. The newest entry in The Practical and Theatrical Scare Actor blog has some helpful advice for ways to respond to difficult guests who are aggressive and belligerent. Continuing our scareacting education, the Youtube Channel Spikima Movies released a video on the art of the Jumpscare. Using examples from the films of David Lynch, the video explores how set-up, setting, sound, and pacing can create the perfect jumpscare to startle audiences. There are many tips that can be applied to haunts and immersive theater as well.

This Fall Great Pumpkin LumiNights will take place at Wild Adventures Theme Park in Valdosta, Georgia. 2021 has proved to be the park's biggest opening season yet, and with its success, park officials have decided to add the new Halloween event. Great Pumpkin LumiNights will feature "larger-than-life" pumpkin sculptures throughout the park. The event has already been implemented in the company's sister theme parks - including Dollywood. The family-friendly experience is a $700,000 investment for the park. On June 30th, Mary Shelley's House of Frankenstein in Bath (UK) will open to the public. This interactive experience/museum is bursting with unusual artifacts and vintage items, multi-sensory environments, and assorted body parts. Guests will step into the dark world of Mary Shelley to learn about her tragic life and come face-to-face with an 8-foot recreation of the literary monster that continues to fascinate the world. After the popularity of their Christmas projection show on the Armoury building in Chatham (Ontario, Canada), The Armoury in Lights event organizers have decided to add a Halloween show for 2021. The Halloween event will take place October 14th - 30th with three shows each night. Each show will be 90 minutes - twice as long as their 2020 shows - and feature projections, dancing, and performances. Last year the event switched to a drive-in format and it will remain that way for 2021 - and new for this year is an illuminated entryway featuring works from 10 artists. Applications for performers and artists will be available soon. In the market to buy a haunted house? Waco Haunted House in Central Texas is for sale by co-owners John & Danea Anderson. After 30 years of operation, the Andersons hope to sell it to a new generation of haunters. The sale price will likely be around $600,000 and will include 2 haunted houses (over 7,000 sq. ft. per house), a 60' mobile home/office, store & warehouse, ticket booth tower & concession building, company van, 3 hearses, storage trailers, and more. If the right purchaser comes along, the haunt can be up and running again for the 2021 season. The house of home haunter Kit Espada (East Providence, Rhode Island) was damaged in a fire this past week. Espada hosts an annual Halloween display in her yard, collecting donations and non-perishable food items for the Rhode Island Community Food Bank Association. Some of the homemade props stored in her garage went up in flames, but luckily no one was harmed in the fire. Espada had planned a clown theme for her 2021 display, but with many of her props damaged or lost in the fire, she is doubtful it will happen. A GoFundMe has been set-up for the Estrada family by members of the haunt community. Descanso Gardens in La Cañada, CA announced the return of Carved for this October. The Halloween event features a mile-long trail lined with thousands of professionally-carved, jack-o-lanterns and sculptures made of natural materials. Other activities include pumpkin carving demonstrations, a hay maze, themed food, and a house made of pumpkins. Tickets for this 3-week event will go on sale in September for members and October for the general public. As we prepare for the haunt season, scareactors may want to strengthen their skills for dealing with aggressive guests. The newest entry in The Practical and Theatrical Scare Actor blog has some helpful advice for ways to respond to difficult guests who are aggressive and belligerent. Continuing our scareacting education, the Youtube Channel Spikima Movies released a video on the art of the Jumpscare. Using examples from the films of David Lynch, the video explores how set-up, setting, sound, and pacing can create the perfect jumpscare to startle audiences. There are many tips that can be applied to haunts and immersive theater as well.

This is an audio podcast episode of a video release. For more information on this podcast visit https://www.stuartoswald.com/p/podcast.html. » Find me everywhere https://linktr.ee/stuartoswald » Related Article https://archive.ph/PpAKB

A native Angeleno, De Camille attended the Lycee Francais at age six and went on to study art and fashion at the Paris American Academy and the Ecole des Beaux Arts in Paris where she had a one-woman sell-out show in Montmartre. The world of the French Cabaret has continued to inspire her work. There is a sense of the collector and traveler in her work having lived abroad for five years. From the Caribbean islands of Montserrat and Grenada to Paris and Bath UK, she takes from the past to update it through her unique and quirky lens. A strong theme in her work is the iconic female form. For ten thousand years we have been haunted and inspired by the dazzling mother/ goddess/ temptress/ angel. Her work is a synthesis of Pop Culture through a dream-like state; her technique is layered. It may start with the collaging of a Blue Print and images to set the scene or create the impressions for the structure of the work. She experiments with various mediums to create altered states of texture such as; saw dust, paint medium; egg yolk; tea bags; paper; found objects. Presently she is living and painting in Happy Valley, Oregon, a bucolic town just outside of Portland with her young family. Contact de Camille: www.coolarthouse.com camille@decamille.com Do you want to live an incredible life? Get started now by reading my book: "Visualizing Happiness in Every Area of Your Life" https://amzn.to/2kvAuXU What is your biggest obstacle to creating an incredible life? You can book a free 15-minute mentoring session with Dr. Kimberley Linert. Click on this booking link: https://calendly.com/drkimberley/15min Please subscribe to the podcast and take a few minutes to review on iTunes, Thank you If you have an amazing story to tell about your life and how you are sharing your gifts and talents with the world, then I would love to have you as a guest on my podcast. Contact me via email: incrediblelifepodcast@gmail.com or private message me on Facebook: www.facebook.com/incrediblelifecreator www.DrKimberleyLinert.com

The Gary Null Show is here to inform you on the best news in health, healing, the environment. Green tea ingredient may ameliorate memory impairment, brain insulin resistance, and obesity Northwest A&F University (China), July 28, 2020 A study published online in The FASEB Journal, involving mice, suggests that EGCG (epigallocatechin-3-gallate), the most abundant catechin and biologically active component in green tea, could alleviate high-fat and high-fructose (HFFD)-induced insulin resistance and cognitive impairment. Previous research pointed to the potential of EGCG to treat a variety of human diseases, yet until now, EGCG's impact on insulin resistance and cognitive deficits triggered in the brain by a Western diet remained unclear. "Green tea is the second most consumed beverage in the world after water, and is grown in at least 30 countries," said Xuebo Liu, Ph.D., a researcher at the College of Food Science and Engineering, Northwest A&F University, in Yangling, China. "The ancient habit of drinking green tea may be a more acceptable alternative to medicine when it comes to combatting obesity, insulin resistance, and memory impairment." Liu and colleagues divided 3-month-old male C57BL/6J mice into three groups based on diet: 1) a control group fed with a standard diet, 2) a group fed with an HFFD diet, and 3) a group fed with an HFFD diet and 2 grams of EGCG per liter of drinking water. For 16 weeks, researchers monitored the mice and found that those fed with HFFD had a higher final body weight than the control mice, and a significantly higher final body weight than the HFFD+EGCG mice. In performing a Morris water maze test, researchers found that mice in the HFFD group took longer to find the platform compared to mice in the control group. The HFFD+EGCG group had a significantly lower escape latency and escape distance than the HFFD group on each test day. When the hidden platform was removed to perform a probe trial, HFFD-treated mice spent less time in the target quadrant when compared with control mice, with fewer platform crossings. The HFFD+EGCG group exhibited a significant increase in the average time spent in the target quadrant and had greater numbers of platform crossings, showing that EGCG could improve HFFD-induced memory impairment. "Many reports, anecdotal and to some extent research-based, are now greatly strengthened by this more penetrating study," said Thoru Pederson, Ph.D., Editor-in-Chief of The FASEB Journal.       Medieval medicine remedy could provide new treatment for modern day infections University of Warwick UK, July 28, 2020 Antibiotic resistance is an increasing battle for scientists to overcome, as more antimicrobials are urgently needed to treat biofilm-associated infections. However scientists from the School of Life Sciences at the University of Warwick say research into natural antimicrobials could provide candidates to fill the antibiotic discovery gap. Bacteria can live in two ways, as individual planktonic cells or as a multicellular biofilm. Biofilm helps protect bacteria from antibiotics, making them much harder to treat, one such biofilm that is particularly hard to treat is those that infect diabetic foot ulcers. Researchers at the University of Warwick, Dr Freya Harrison, Jessica Furner-Pardoe, and Dr Blessing Anonye, have looked at natural remedies for the gap in the antibiotic market, and in the paper, 'Anti-biofilm efficacy of a medieval treatment for bacterial infection requires the combination of multiple ingredients' published in the journal Scientific Reports today the 28 July, researchers say medieval methods using natural antimicrobials from every day ingredients could help find new answers. The Ancientbiotics research team was established in 2015 and is an interdisciplinary group of researchers including microbiologists, chemists, pharmacists, data analysts and medievalists at Warwick, Nottingham and in the United States. Building on previous research done by the University of Nottingham on using medieval remedies to treat MRSA, the researchers from the School of Life Sciences at University of Warwick reconstructed a 1,000-year-old medieval remedy containing onion, garlic, wine, and bile salts, which is known as 'Bald's eyesalve', and showed it to have promising antibacterial activity. The team also showed that the mixture caused low levels of damage to human cells. They found the Bald's eyesalve remedy was effective against a range of Gram-negative and Gram-positive wound pathogens in planktonic culture. This activity is maintained against the following pathogens grown as biofilms:   1. Acinetobacter baumanii- commonly associated with infected wounds in combat troops returning from conflict zones. 2. Stenotrophomonas maltophilia- commonly associated with respiratory infections in humans 3. Staphylococcus aureus- a common cause of skin infections including abscesses, respiratory infections such as sinusitis, and food poisoning. 4. Staphylococcus epidermidis- a common cause of infections involving indwelling foreign devices such as a catheter, surgical wound infections, and bacteremia in immunocompromised patients. 5. Streptococcus pyogenes - causes numerous infections in humans including pharyngitis, tonsillitis, scarlet fever, cellulitis, rheumatic fever and post-streptococcal glomerulonephritis.   All of these bacteria can be found in the biofilms that infect diabetic foot ulcers and which can be resistant to antibiotic treatment. These debilitating infections can lead to amputation to avoid the risk of the bacteria spreading to the blood to cause lethal bacteremia. The Bald's eyesalve mixtures use of garlic, which contains allicin, can explain activity against planktonic cultures, however garlic alone has no activity against biofilms, and therefore the anti-biofilm activity of Bald's eyesalve cannot be attributed to a single ingredient and requires the combination of all ingredients to achieve full activity. Dr Freya Harrison, from the School of Life Sciences at the University of Warwick comments: "We have shown that a medieval remedy made from onion, garlic, wine, and bile can kill a range of problematic bacteria grown both planktonically and as biofilms. Because the mixture did not cause much damage to human cells in the lab, or to mice, we could potentially develop a safe and effective antibacterial treatment from the remedy. "Most antibiotics that we use today are derived from natural compounds, but our work highlights the need to explore not only single compounds but mixtures of natural products for treating biofilm infections. We think that future discovery of antibiotics from natural products could be enhanced by studying combinations of ingredients, rather than single plants or compounds. In this first instance, we think this combination could suggest new treatments for infected wounds, such as diabetic foot and leg ulcers. " Jessica Furner-Pardoe, from the Medical School at the University of Warwick comments: "Our work demonstrates just how important it is to use realistic models in the lab when looking for new antibiotics from plants. Although a single component is enough to kill planktonic cultures, it fails against more realistic infection models, where the full remedy succeeds." In previous research Christina Lee, from the School of English at the University of Nottingham, had examined the Bald's Leechbook, an Old English leatherbound volume in the British Library, to see if it really works as an antibacterial remedy. The Leechbook is widely thought of as one of the earliest known medical textbooks and contains Anglo-Saxon medical advice and recipes for medicines, salves and treatments. Christina adds: "Bald's eyesalve underlines the significance of medical treatment throughout the ages. It shows that people in Early Medieval England had at least some effective remedies. The collaboration which has informed this project shows the importance of the arts in interdisciplinary research."   First clinical trial of its kind studies whether cannabidiol could help treat cannabis use disorder, compared to placebo University of Bath (UK), July 28, 2020   Prescription medication of cannabis extract cannabidiol, or CBD, is safe for daily use in treating cannabis use disorder, and could help people to cut down on cannabis use, according to an initial randomised controlled trial published in The Lancet Psychiatry journal. The study is the first to report that daily prescribed medical-use CBD use can cause reduction in cannabis use among people with cannabis use disorder, but the four-week study was not designed to provide robust estimates of the magnitude or duration of efficacy and further studies are needed. Researchers found an optimal daily dose of between 400mg and 800mg of CBD, which is considerably higher than concentrations found in CBD products that are available without prescription (which typically contain around 25mg CBD). They warn that such products should not be used for medicinal purposes. The authors say that these findings are important in light of major policy changes surrounding the production and sale of cannabis products, increases in the number of people entering treatment for cannabis use disorders worldwide, and the current absence of recommended treatments for cannabis use disorder. Dr Tom Freeman, the study's lead author and Director of the Addiction and Mental Health Group at the University of Bath, UK, said: "Our study provides the first causal evidence to support cannabidiol, or CBD, as a treatment for cannabis use disorders. This is encouraging, as there are currently no drug treatments for cannabis addiction. CBD products are widely available in many countries but we would not advise people to self-medicate with these products. People with concerns about their cannabis use should always speak to a healthcare professional in the first instance." [1] Cannabis addiction affects an estimated 22 million people worldwide - similar to the prevalence of opioid use disorders - and the proportion of people seeking help for cannabis use disorders has risen in all world regions apart from Africa. However, there are currently no medications recommended for the treatment of cannabis use disorders. Cannabidiol, also known as CBD, is one of more than 80 chemicals present in cannabis. By itself, CBD has been reported to induce feelings of relaxation and calm, but it does not cause the "high" associated with cannabis use, which is caused by a different chemical called tetrahydrocannabinol, or THC. As a result, CBD is sold legally in many countries in oils, capsules, creams, tea and other products. Previous studies have suggested that taking CBD products could help to reduce withdrawal symptoms in people who are actively trying to quit cannabis use. However, it hasn't been possible to determine whether these effects were due to CBD, because the studies either used an open-label design (where the participants knew what medications they were taking and so the results could have been biased), or CBD was given together with THC so it wasn't possible to say to which chemical the effects were attributable. In this latest study, researchers carried out the first randomised clinical trial of cannabidiol for the treatment of cannabis addiction. All 82 people who took part in the study had been diagnosed with a cannabis use disorder of at least moderate severity, which means they experienced at least four out of 11 possible symptoms of addiction. They had all expressed a desire to quit within the next month, and had tried to quit on at least one occasion before. Participants were randomly assigned to treatment groups and asked to take two capsules of CBD twice daily for four weeks. The placebo group were given sham capsules containing no CBD, while the others received a daily dose of either 200mg, 400mg or 800mg CBD. All of the participants received six counselling sessions designed to help them quit using cannabis, which took place before and during the study period. Weekly urine samples were tested for levels of THC to assess how much cannabis had been consumed in the past week. Participants were also asked to report how many days they had abstained from using cannabis that week. The trial used an adaptive design to identify which doses of CBD were effective or ineffective compared to placebo. In the first stage of the trial, 12 people per group were assigned to either placebo, 200mg, 400mg or 800mg CBD (48 total). After the first phase of the study, the 200mg dose was found to be ineffective and these participants were removed from the trial. A further 34 people were recruited to the second stage of the study and randomly assigned to receive daily doses of either the placebo (11 people), 400mg CBD (12 people) or 800mg CBD (11 people). Daily CBD doses of 400mg and 800mg were both found to reduce participants' cannabis intake (reducing THC levels in the urine by -94.21ng/mL and -72.02ng/mL, respectively). In addition, abstinence from cannabis use increased by an average of 0.5 days per week in the group who received the 400mg daily dose of CBD and 0.3 days per week in the group who received 800mg CBD daily. The researchers observed no difference in side effects experienced by the placebo group and those receiving any dose of CBD. 77 of 82 participants completed the treatment and those who dropped out did so because of missing study visits, being lost to follow up, not taking the study medication, or taking additional medications, and not because of the CBD treatment. There were no serious adverse events during the study, suggesting that CBD is safe and well tolerated at the doses tested. Professor Valerie Curran, senior author and Director of the Clinical Psychopharmacology Unit at University College London, UK, said: "Our findings indicate that CBD doses ranging from 400mg to 800mg daily have the potential to reduce cannabis use in clinical settings, but higher doses are unlikely to bring any additional benefit. Larger studies are needed to determine the magnitude of the benefits of daily CBD for reducing cannabis use." [1] The study was carried out over a four week treatment period with follow up extending to six months. The researchers say additional research is needed to investigate the extent to which their findings translate to different durations of treatment. Studies are also needed to investigate whether CBD directly reduces cannabis use or if it reduces other mental health symptoms which might indirectly affect cannabis use, such as anxiety.   Pessimistic outlook on life linked to life expectancy QIMR Berghofer Medical Research Institute (Australia). July 28, 2020   A new QIMR Berghofer Medical Research Institute study has found people who are strongly pessimistic about the future are at greater risk of dying earlier than those who are not pessimists. The researchers also found, however, that being an optimist did not extend life expectancy. The lead researcher, Dr. John Whitfield from QIMR Berghofer's Genetic Epidemiology group, said study participants who scored higher on pessimism in a questionnaire were likely to die on average two years earlier than those with low scores. "We found people who were strongly pessimistic about the future were more likely to die earlier from cardiovascular diseases and other causes of death, but not from cancer," Dr. Whitfield said. "Optimism scores on the other hand did not show a significant relationship with death, either positive or negative. "Less than nine percent of respondents identified as being strongly pessimistic. There were no significant differences in optimism or pessimism between men and women. On average, an individual's level of either optimism or pessimism increased with age. "We also found depression did not appear to account for the association between pessimism and mortality." The researchers used data collected from almost 3,000 participants who completed the Life Orientation Test as part of a broader questionnaire that looked at the health of Australians aged over 50 between 1993 and 1995. The participants were invited to agree or disagree with a number of statements including positive statements such as, 'I'm always optimistic about my future' or negative statements such as, 'If something can go wrong for me, it will'. The participants' details were then cross checked with the Australian National Death Index in October 2017 to find out how many people had died and their cause of death. (More than 1,000 participants had died.) Previous studies have shown a correlation between optimism and pessimism and specific diseases such as cardiovascular disease or stroke, but most previous studies also put optimism and pessimism on one scale. This resulted in people who received low scores on the pessimism questions being classed as optimists, but Dr. Whitfield said that was not always an accurate reflection of people's outlooks. "Optimism and pessimism are not direct opposites," Dr. Whitfield said. "The key feature of our results is that we used two separate scales to measure pessimism and optimism and their association with all causes of death. "That is how we discovered that while strong pessimism was linked with earlier death, those who scored highly on the optimism scale did not have a greater than average life expectancy. "We think it's unlikely that the disease caused the pessimism because we did not find that people who died from cancer had registered a strong pessimism score in their tests. If illness was leading to higher pessimism scores, it should have applied to cancers as well as to cardiovascular disease." Dr. Whitfield said the research findings raised questions about the practical health benefits of training people out of pessimism. "Understanding that our long term health can be influenced by whether we're a cup-half-full or cup-half-empty kind of person might be the prompt we need to try to change the way we face the world, and try to reduce negativity, even in really difficult circumstances." The study findings have been published this week in the journal Scientific Reports.   Wealthier men are more likely to develop high blood pressure Hokkaido University Graduate School of Medicine (Japan), 26 July 2020:    Working men with higher incomes are more likely to develop high blood pressure, reports a study presented at the 84th Annual Scientific Meeting of the Japanese Circulation Society (JCS 2020). JCS 2020 takes place online from 27 July to 2 August in conjunction with the Asian Pacific Society of Cardiology Congress 2020 (APSC 2020). Joint scientific sessions are being held by the European Society of Cardiology (ESC) and JCS as part of the ESC Global Activities programme.1 "Men with higher incomes need to improve their lifestyles to prevent high blood pressure," said study author Dr. Shingo Yanagiya of the Hokkaido University Graduate School of Medicine, Sapporo, Japan. "Steps include eating healthily, exercising, and controlling weight. Alcohol should be kept to moderate levels and binge drinking avoided." More than one billion people have high blood pressure worldwide.2 Around 30-45% of adults are affected, rising to more than 60% of people over 60 years of age. High blood pressure is the leading global cause of premature death, accounting for almost 10 million deaths in 2015. Of those, 4.9 million were due to ischaemic heart disease and 3.5 million were due to stroke. Japan alone has more than 10 million people with high blood pressure, and the number continues to rise. Dr. Yanagiya said: "High blood pressure is a lifestyle-related disease. As a physician seeing these patients I wanted to know if risk varies with socioeconomic class, to help us focus our prevention efforts." This analysis of the J-HOPE3 study examined the relationship between household income and high blood pressure in Japanese employees. A total of 4,314 staff (3,153 men and 1,161 women) with daytime jobs and normal blood pressure were enrolled in 2012 from 12 workplaces. Workers were divided into four groups according to annual household income: less than 5 million, 5 to 7.9 million, 8 to 9.9 million, and 10 million or more Japanese yen per year. The researchers investigated the association between income and developing high blood pressure over a two-year period. Compared to men in the lowest income category, men in the highest income group were nearly twice as likely to develop high blood pressure. Men in the 5 to 7.9 million and 8 to 9.9 million groups had a 50% higher risk of developing high blood pressure compared to men with the lowest incomes, although the positive association did not reach statistical significance in the 8 to 9.9 million group. The findings were consistent regardless of age, and were independent of baseline blood pressure, worksite, occupation, number of family members, and smoking. The relationships were slightly weakened after accounting for alcohol consumption and body mass index (BMI; kg/m2), both of which were higher for men in the higher income groups. In women, there was no significant link between income and blood pressure. However, women with higher household income tended to have a lower risk of developing high blood pressure. "Some previous Japanese surveys have reported that higher household income is associated with more undesirable lifestyles in men, but not in women," said Dr. Yanagiya. "Our study supports this: men, but not women, with higher household incomes were more likely to be obese and drink alcohol every day. Both behaviours are major risk factors for hypertension." He concluded: "Men with high-paying daytime jobs are at particular risk of high blood pressure. This applies to men of all ages, who can greatly decrease their chance of a heart attack or stroke by improving their health behaviours." Dr. Yusuke Yoshikawa, public relations coordinator for JCS 2020, said: "Hypertension is one of the most important risk factors of cardiovascular disease in Japan, because the average daily salt intake in Japan (approx. 10 g/day) is much higher than desired. As the current guidelines2 strongly recommend healthy lifestyle to control high blood pressure, this study suggests a potential key to successful intervention for those who are at risk of heart disease and stroke." Professor Michel Komajda, a Past President of the ESC and course director of the ESC programme at JCS 2020, said: "The ESC is delighted to be part of JCS 2020 in Kyoto. We value our special partnership with JCS and the high quality of Japanese research. Japan is among the top submitters of abstracts to ESC Congress."   Acute exercise has beneficial effects on the immune system during prostate cancer Victoria University (Australia), July 28, 2020   New research published this week in Experimental Physiology found that in prostate cancer survivors, a moderate bout of exercise kept the cell count of certain type of immune cells at a normal level, suggesting the exercise is safe for prostate cancer survivors. After 24 hours after a moderate bout of cycling, the immune cell count of natural killer (NK) cells, part of the body's first line of defence, had returned to resting levels. Prostate cancer treatments, including androgen deprivation therapy (ADT), have numerous adverse effects that reduce physical function and quality of life. Exercise is recommended for cancer survivors to reduce the side effects of treatment and has shown to have many benefits. However, the effects of prostate cancer treatment and acute exercise on the immune system have only been briefly examined. Exercise oncology guidelines were initially based on the responses seen in healthy, older adults. But individuals with cancer have different physiological responses to exercise, many of which we are only just beginning to understand. Exercise helps the immune system mobilise by causing NK cells to move into the blood and be transported them to areas of need, such as sites of infection or tumours. At the tissues, these cells move out of circulation and in cancer patients they can the infiltrate the tumour and potentially slow the tumour's rate of growth. This has been shown very elegantly in animal models but the exercise and immune response in cancer survivors is limited, with only a few studies in prostate cancer. The researchers, based at Victoria University in Australia, had volunteers (11 cancer survivors currently receiving ADT treatment, and 14 men with prostate cancer not on ADT, and 8 healthy controls) completed a cycling task to determine their maximal aerobic fitness. The researchers chose to use a moderate intensity exercise session that was consistent with current exercise oncology guidelines but was also a bout that would be practical for prostate cancer survivors to perform on their own. To ensure that the exercise bout used to stimulate the immune system was the same degree of difficulty for everyone, they standardised based on their maximal effort. To determine immune function, they obtained blood samples before exercise, immediately after and 2h after they finished cycling. The participants then came back the next day (24h) after exercise, and immune function was assessed again after one night of recovery. They also measured several key hormone levels, including adrenaline and noradrenaline, as they play a role in activating and mobilising the NK immune cells. The researchers found that 24 hours after a moderate bout of cycling, the immune cell count of natural killer (NK) cells, part of the body's first line of defence, had returned to resting levels. They also showed that the immune cell mobilisation with exercise does not appear to be significantly altered during prostate cancer treatment, which provides direct evidence that acute exercise that falls within current oncology guidelines also appears to be beneficial for the immune system. A limitation of the study is the modest sample size, and also that they examined cytokines and proteins that are related to NK cell function but did not directly assess the killing capacity of the NK cells. Erik D Hanson, first author on the study said, "One of the most enjoyable aspects of working with these men is how willing these men are to help their fellow prostate cancer survivors. Many of them realise that these studies are not likely to benefit them directly. However, they do not hesitate to volunteer and are willing to do just about whatever is asked of them for the collective good."   Study shows mango consumption has positive impact on inflammatory bowel disease Texas A&M University, July 29, 2020  Initial results of a study by researchers in the department of nutrition and food science at Texas A&M University in College Station show mango consumption has a positive impact on people with inflammatory bowel disease. Dr. Susanne Talcott, Texas A&M AgriLife Research scientist, and others recently investigated the use of fresh mangoes as an adjuvant to conventional therapy in mild to moderate inflammatory bowel disease. "Inflammatory bowel disease presents a major risk factor for colon cancer with the most common forms of this disorder being Crohn's disease and ulcerative colitis," Talcott said. "Previous studies indicate that IBD affects about 1.5 million individuals in the U.S., about 2.2 million in Europe and many more in other countries." "Colorectal cancer can develop from precursor lesions that can be caused by inflammatory bowel disease over periods of 10 to 15 years, which provides an extended time for preventive measures," she said. Talcott said multiple studies have demonstrated the health benefits of secondary plant compounds in fruits and vegetables including pomegranate, citrus and curcuminoids, and polyphenolics have been found to reduce inflammatory processes in chronic diseases such as cardiovascular disease, cancer and inflammatory bowel diseases. "However, few human clinical studies using polyphenolics in the treatment of inflammatory bowel disease have been conducted," she said. Mangos are rich in gallotannins, a group of large molecular polyphenols that can be broken down to small, absorbable, bioactive molecules by certain intestinal bacteria. To investigate the impact of mango polyphenolics on humans, Talcott's team, which included husband Dr. Stephen Alcott, also an AgriLife Research scientist, designed a clinical trial conducted at Texas A&M. Trial subjects were recruited in the College Station area and at the Ertan Digestive Disease Center at the Memorial Hermann Hospital in Houston under the direction of Dr. Andrew Dupont, MD. The study was designed as a controlled clinical pilot trial in subjects with mild-to-moderate active Crohn's disease or mild-to-moderate ulcerative colitis. Subjects ate mango as an adjunct to their common drug treatment for mild-to-moderate IBD. Male and female individuals from 18 to 79 years old with Crohn's disease or ulcerative colitis were enrolled in the study. Those included were individuals undergoing current or previous IBD drug treatment within the past six months and those on a stable drug regimen for at least three weeks before the start of the treatment phase of the study. Excluded from the study were those with chronic health conditions or recurrent hospitalizations, as well as those who smoked more than one pack of cigarettes per week, had a current liver or renal dysfunction, were pregnant or lactating or had a known lactose intolerance, gluten sensitivity or celiac disease. Also excluded were those with planned or scheduled IBD-related surgery, current IBD-related intestinal stricture, current infection with C. difficile or a previous bowel resection. Medical personnel evaluated more than 300 subjects for the study based on medical records or surveys. Twenty subjects participated in some aspect of the study, including the screening, with 14 completing the study. Subjects were provided with and asked to include 200-400 grams of commercially available frozen mangos of the Keitt variety in their daily diet. They were asked to increase their mango consumption slowly over the first week. "Since the tolerability of large amounts of fiber-rich fruit varies between subjects and for each patient over time, this study allowed subjects to consume mango within a range rather than a fixed amount," Talcott said. "This range was from 200 grams twice daily to 400 grams three times a day." She said subjects could skip their mango consumption or reduce it to accommodate any possible digestive issues, but were required to document their daily mango intake. Subjects who underwent an endoscopy before the beginning of this study were asked to wait at least one week before the study treatment could be started. The treatment phase of the study was eight weeks. "Despite a relatively small subject number, this study yielded significant findings and several biomarkers would have been significantly reduced with a higher number of subjects," Talcott said. She said symptoms of ulcerative colitis were significantly reduced in the test subjects and several biomarkers associated with inflammation were decreased after eight weeks of mango consumption. Additionally, the presence of GRO, a molecule associated with colon cancer growth, was significantly reduced. "Intestinal Lactobacilli and other beneficial probiotic bacteria were significantly increased after the consumption of mango as were certain short-chain fatty acids essential for a healthy intact intestinal tract," she said. Talcott said high endotoxin levels are not only associated with intestinal inflammation but also with other chronic inflammatory diseases, but after eight weeks of mango consumption, high endotoxin levels in blood plasma were significantly decreased. "Taken together, our results indicate mango intake exerted beneficial effects in the progression and severity of the IBD after eight weeks of nutritional intervention," she said. She noted mango consumption might also mitigate inflammation in part by improving the composition of the intestinal microbiota and decreasing the serum endotoxin level. "All subjects who completed the study stated they would continue to consume mangoes regularly and will recommend this to others who suffer from IBD and also tell their physicians," Talcott said. She said if mango or any other polyphenolic-rich food can be identified as helpful in shortening or reducing severity of episodes of inflammatory bowel disease, the addition of mango polyphenolics to conventional IBD drug treatment could have a significant positive impact on public health.   Meta-analysis supports potential of omega-3s for ADHD Kings College London, July 28, 2020 Omega-3s fatty acid supplements may improve symptoms and cognitive performance in children and adolescents with attention deficit hyperactivity disorder (ADHD), according to a meta-analysis of gold standard clinical trials. Data from seven clinical trials involving over 500 children and adolescents indicated that omega-3s were associated with improvements in clinical symptoms of ADHD, while data from three clinical trials involving over 200 children and adolescents indicated a positive impact on cognitive measures associated with attention. “[W]e provide strong evidence supporting a role for n3-PUFAs deficiency in ADHD, and for advocating n-3 PUFAs supplementation as a clinically relevant intervention in this group, especially if guided by a biomarker-based personalization approach,” wrote the authors, led by Jane Pei-Chen Chang from King's College London, in Neuropsychopharmacology . Boosting EPA/DHA intakes Commenting independently on the meta-analysis, Harry Rice, PhD, VP of regulatory & scientific affairs for the Global Organization for EPA and DHA Omega-3s (GOED): “In the past, I've been lukewarm on whether or not increasing EPA/DHA intake benefits children with ADHD. Results from this meta-analysis put me a little closer to believing. “Minimally, given the low side effect profile of omega-3s versus the drugs of choice to treat ADHD, I would highly recommend first increasing intake of EPA/DHA. This is particularly true if a child doesn't eat at least two servings of fatty fish a week or doesn't take an omega-3 supplement on a regular basis.” Meta-analysis details The new meta-analysis was performed using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines and used established scientific literature databases to identify appropriate studies for inclusion. Data from seven randomized controlled trials (RCTs) with 534 young people indicated that that omega-s3 supplementation significantly improved inattention and hyperactivity symptoms, according to parental reports. Additional analysis revealed that the improvements in hyperactivity were only observed when doses of EPA (eicosapentaenoic acid) of 500 mg/day or more were used. Interesting, the researchers did not find improvements in hyperactivity and inattention when they looked at teacher's reports, unlike what was reported by parents. Omega-3 supplements were associated with improvements in select measures of cognitive performance, said the researchers. “N-3 PUFAs are crucial for optimal neurotransmitter function: for example, incorporating more EPA and DHA in the cell membrane can increase cholesterol efflux, modulate lipid raft clustering and disruption, and affect the function of the dopamine transporter (DAT), which in turn may affect attention and executive function by regulating synaptic dopamine levels,” wrote the researchers. Omega-3 levels Data from case-control studies were also collected to assess if omega-3 levels were also associated with ADHD, with results indicating that children and adolescents with ADHD had lower levels of EPA, DHA (docosahexaenoic acid),and total omega-3s. “In the context of ‘personalised medicine', it is tempting to speculate that a subpopulation of youth with ADHD and with low levels of n-3 PUFAs may respond better to n-3 PUFAs supplementation, but there are no studies to date attempting this stratification approach,” wrote the researchers. “However, we have [previously] shown that individuals at genetic risk of developing depression in the context of the immune challenge, interferon-alpha (IFN-alpha), have lower levels of RBCs n3-PUFAs, and that n-3 PUFAs supplementation prevents the onset of IFN-alpha-induced depression, arguably by replenishing the endogenously low anti-inflammatory PUFAs in the ‘at risk' individuals.”

In this episode Alex chats to comedian Mark Olver, café owner Sus Davy and podcast host Hope Light about life in lockdown week 2 (in the UK), the situation in the US, takeaways and Mark's desire to show off. Listen carefully and you'll hear our producer Dave pipe up too! Guest links: - Cascara Cafe, Bath UK - https://www.instagram.com/cascarabath/ - Mark's new YouTube show 'Who Said That?' - https://www.youtube.com/watch?v=Ni4pn3bKGjM&t=18s - Femidish podcast - https://www.facebook.com/femidish/ ------------

"We're not a big teaching hospital [...] and I think there is a slightly different perspective..." This piece focuses on the realities of preparing for and dealing with COVID 19 patients in the town of Bath in the UK. Innovation with staff training, cautionary tales regarding our advance warning of the current situation and fluctuating guidelines are the opening points of discussion before a fascinating deep dive into the potential merits of video laryngoscopy. Further discussion includes reflections on the anaesthetics and forms of treatment which might be used in such a case. Presented by Desiree Chappell and Monty Mythen with their guest Professor Tim Cook, Consultant in Anaesthesia and ICM, Royal United Hospitals, Bath. Email us contact@topmedtalk.com If you found this piece interesting there is more from Tim Cook here: https://www.topmedtalk.com/sunday-special-should-direct-laryngoscopy-be-consigned-to-the-history-books/ Thank you to our sponsor Edwards Lifesciences. Edwards clinical education (ECE): https://www.edwards.com/clinicaleducation

In this first episode of Tripping With Friends, Curtis chats with his friend, Brandy, about visiting Bath in the United Kingdom. --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app

"We're going Roman spa to style your last minute holiday gifts at the most relaxing town to shop in on the planet - no Trojan horse required!"

In July of 2012, the Trump Organization opened a course, Trump International Golf Links, just north of Aberdeen on the northeast coast of Scotland. To this day, Trump continues to declare it “perhaps the greatest golf course anywhere in the world.” The development of Trump International Golf Links, Scotland, however, was contested and politicized from the beginning. In this episode of Somatic, we talked with two noted scholars of golf, sport and environmentalism - Dr. Brad Millington from the University of Bath (UK) and Dr. Brian Wilson from the University of British Columbia - and asked them to reflect on the case of Trump International Golf Links, Scotland, as well as the question of Anthropocentrism in the study of sport and politics. Our hope is that the episode appeals to the sport scholar and lay podcast listener alike, as we explore a fascinating context of political, social, and environmental contestation, while considering how scholars can better understand the role of the non-human in such contexts. You can find our full blog post accompanying this episode, as well as links to the scholars' works and media coverage of the Trump International Golf Links, Scotland case, on our website at http://www.somaticpodcast.com.

Rob Hyde, AV Manager, at the University of Bath UK joins the show discussing classroom and event operations, deploying spaces, including a great method for getting faculty trained (hint: ask for their time at a place they'll all be present), the LITEbox, and most importantly our common allegiance to Aston Villa. P.s., if you ever wanted to get yourself on the podcast, just follow Rob's method. This episode is sponsored by Sound Productions at SoundPro.com.

Henrypmiller and Casimir the Swede head to Bath UK for a bit of international action. The sound quality of this episode varies a little. Hopefully its listenable. We start with a run down of some of the lists and matchups. Casimir and Henry go through their games at the tournament and we get into some analysis on the Highborn Elves and Undying Dynasties. If you can make it to the end you will hear Ulrik Sing.

Social Protection, also der soziale Schutz, den ein Staat seinen Bewohner/innen bietet, ist ein maßgebliches Instrument für das Wohlbefinden und die Lebensqualität in einem Land. Dieser Schutz umfasst viele Bereiche des täglichen Lebens und des persönlichen Wohlbefindens, sei es Gesundheit, Bildung, Arbeit oder die Unterstützung von besonders gefährdeten Gruppen wie von Armut betroffene oder körperlich oder geistig beeinträchtigte Menschen.Traditionell bestand Social Protection im Bereich der Armutsbekämpfung aus Sachleistungen, wie etwa Lebensmitteln, oder aus Diensten, wie das zur Verfügung stellen von Gesundheitsversorgung oder Bildungseinrichtungen. Erst nach und nach bekamen Geldtransfers hier Bedeutung. Brasilien startete 2003 das Programm Bolsa Escola/Bolsa Família, das eine Vorreiterrolle einnahm. Diese Geldtransfers waren allerdings an Bedingungen wie regelmäßiger Schulbesuch und das in Anspruch nehmen von Gesundheitsleistungen gebunden.Seit einiger Zeit laufen auch vereinzelte Pilotprojekte zu unkonditionalen Geldtransfers, also Geldleistungen die jeder einer bestimmten Gruppe bekommt, ohne dafür Auflagen zu erfüllen, oder zu bedingungslosem Grundeinkommen, also der flächendeckenden regelmäßigen Auszahlung an alle Bürger/innen eines Staates, sowohl im globalen Norden als auch im globalen Süden.Barbara Rohregger befasst sich seit langem mit Social Protection und Geldtransfers, aktuell insbesondere in Ghana und Kenya. Sie wird in dieser Sendung zu Ihren Erfahrungen in diesem Bereich und zur aktuellen Diskussion sprechen. Im Interview gibt Jurgen de Wispelaere einen Überblick zu der Thematik.Gestaltung und Moderation: Doris Bauer (Verantwortlich für den Sendungsinhalt)Gast: Dr. Barbara Rohregger, selbständige Gutachterin für Sozialpolitik und Soziale Sicherung in Entwicklungs- und Transformationsländern, wissenschaftliche Mitarbeiterin in dem Forschungsprojekt „Social and Health Policies for Inclusive Growth in Ghana and Kenya“ der Hochschule Bonn-Rhein-SiegIm Interview: Dr. Jurgen de Wispelaere, Sozialwissenschafter mit Schwerpunkt Basic Income, Universität Bath/UK und Universität Tampere/FinnlandMusik: The Man in Washington - Every type of cloud; Sickboys and Lowmen - I've got it all, All rivers; The Dada Weatherman - Lost to me, Down below. Nachzuhören auf Jamendo, einer Community für freie, legale und unlimitierte Musik, die unter Creative Commons Lizenzen veröffentlicht wurde.

jam's Dev Camp is back with something a little different this week: Rick Donohoe, Account Manager at Microserve in Bristol, presents a case study about how his company delivered six sites on a fixed budget, 5-site contract. He gives some great general and specific tips on making a project like this successful. I saw Rick do a shorter version of this at Drupal Camp Bristol 2015 and thought that the information he has to share is valuable and that many of us could benefit from it. Thanks to Rick and Microserve for sharing! Read the full post and see the conversation video at the Acquia Developer Center: https://dev.acquia.com/podcast/204-drupal-case-study-roman-baths-bath-uk

This Lecture titled ‘Having a Vision’ was the first of a series of lectures conducted in the ‘Making Our Mark’ UK tour. Having a Vision was a talk done in Bath-UK. Sheikh Sajid highlights the importance of having vision and focus in our lives as believers, through analogies and different life experiences, Sh.Sajid teaches this ... Read more

This Lecture titled ‘Having a Vision’ was the first of a series of lectures conducted in the ‘Making Our Mark’ UK tour. Having a Vision was a talk done in Bath-UK. Sheikh Sajid highlights the importance of having vision and focus in our lives as believers, through analogies and different life experiences, Sh.Sajid teaches this ... Read more

This Lecture titled ‘Having a Vision’ was the first of a series of lectures conducted in the ‘Making Our Mark’ UK tour. Having a Vision was a talk done in Bath-UK. Sheikh Sajid highlights the importance of having vision and focus in our lives as believers, through analogies and different life experiences, Sh.Sajid teaches this ... Read more

This Lecture titled ‘Having a Vision’ was the first of a series of lectures conducted in the ‘Making Our Mark’ UK tour. Having a Vision was a talk done in Bath-UK. Sheikh Sajid highlights the importance of having vision and focus in our lives as believers, through analogies and different life experiences, Sh.Sajid teaches this ... Read more

This Lecture titled ‘Having a Vision’ was the first of a series of lectures conducted in the ‘Making Our Mark’ UK tour. Having a Vision was a talk done in Bath-UK. Sheikh Sajid highlights the importance of having vision and focus in our lives as believers, through analogies and different life experiences, Sh.Sajid teaches this ... Read more