Podcasts about cannabinoids

Annette Lopez, MD, Medical Toxicologist and Emergency Medicine Physician, Oregon Poison Center, OHSU - Portland, OregonCME Credit Available for all Providence ProvidersIn order to claim CME credit, please click on the following link:⁠ ⁠ https://forms.office.com/r/m6zkGuM6Uw⁠⁠ or copy & paste into your browser).Accreditation Statement: Providence Oregon Region designates this enduring material activity for a maximum of 1.0 AMA PRA Category 1  creditTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.Providence Oregon Region is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.Planning Committee & Faculty Disclosure: The planning committee and faculty have indicated no relevant financial relationships with an ACCME-defined ineligible company. Their planning contributions were evidence-based and unbiased. All financial relationships (if any) have been mitigated.Original Date: May 21, 2026End Date: May 20, 2027

Annette Lopez, MD, Medical Toxicologist and Emergency Medicine Physician, Oregon Poison Center, OHSU - Portland, OregonCME Credit Available for all Providence ProvidersIn order to claim CME credit, please click on the following link:⁠ ⁠ https://forms.office.com/r/m6zkGuM6Uw⁠⁠ or copy & paste into your browser).Accreditation Statement: Providence Oregon Region designates this enduring material activity for a maximum of 1.0 AMA PRA Category 1  creditTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.Providence Oregon Region is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.Planning Committee & Faculty Disclosure: The planning committee and faculty have indicated no relevant financial relationships with an ACCME-defined ineligible company. Their planning contributions were evidence-based and unbiased. All financial relationships (if any) have been mitigated.Original Date: May 21, 2026End Date: May 20, 2027

It's In The News, where we bring you the top diabetes stories and headlines happening now. Top stories this week: Dexcom shares details of its next generation CGM, T1D and GLP-1 studies, weight loss management on GLP-1 medications updates, all-in-one CGM and pump, and more! Announcing Community Commericals! Learn how to get your message on the show here. Learn more about studies and research at Thrivable here Please visit our Sponsors & Partners - they help make the show possible! Omnipod - Simplify Life All about Dexcom  All about VIVI Cap to protect your insulin from extreme temperatures The best way to keep up with Stacey and the show is by signing up for our weekly newsletter: Sign up for our newsletter here Here's where to find us: Facebook (Group) Facebook (Page) Instagram Check out Stacey's books! Learn more about everything at our home page www.diabetes-connections.com  Episode transcript: XX Dexcom announces some features of it's next generation CGM – the G8. We've been talking about this with CEO Jake Leach for a while now – it will be a 50% smaller with what they're calling advanced sensing capabilities. According to Leach, G8 will adapt to the physiologic variability of each user. It has additional technology built in, based on a new silicon chip design and algorithm. 15 day wear is now the baseline for all Dexcom sensors moving forward. At launch the G8 will only measure glucose but the plan is for a multi-analyte version to follow. That would measure ketones and potassium. Ketones we know – but potassium is very important for people with kidney and possible for people taking some diabetes meds. It's an interesting space to watch.. btw, analyte is just a medical word for the specific thing you're measuring – the target of the test you're running. we're going to hear that word a lot I think..   Looks like an FDA submission for the G8 next year.. with an outside the US launch the following year. https://www.drugdeliverybusiness.com/dexcom-unveils-next-gen-g8-cgm/ XX Glucotrack has submitted its implantable continuous blood glucose monitor (CBGM) for FDA IDE, that's investigational device exemption and would enable the company to initiate a U.S. clinical study for the fully implantable technology. Rutherford, New Jersey-based Glucotrack's device features no on-body external component. The company aims to offer it for three years of continuous, accurate blood glucose monitoring for a more convenient, less intrusive solution. Unlike traditional CGMs that measure glucose in interstitial fluid, the CBGM measures glucose levels directly from the blood. The implant goes five centimeters within the subclavian vein. Glucotrack's active implantable device has a small battery and some electronics that go just under the skin in the pectoral region. The location of the implant is not in a major vessel, but the implant can measure real-time glucose levels as pulsatile blood flows over the tip of the sensor. https://www.drugdeliverybusiness.com/glucotrack-submits-long-term-implantable-cbgm-fda-ide/ XX PharmaSens today announced the publication of data from the first clinical study evaluating its all-in-one insulin patch pump offering. The all-in-one pump pairs the Niaa Essential insulin patch pump with the SynerG continuous glucose monitor (CGM) sensor developed by Pacific Diabetes Technologies. However, this system would be one device that features both the pump and CGM technology.   PharmaSens and SiBionics also have a collaboration aimed at developing the all-in-one solution. They are jointly developing the next-generation Niia insulin patch pump with a SiBionics CGM. PharmaSens expects a second feasibility study in the second quarter to evaluate the next-generation pump with SiBionics' CGM.   PharmaSens says the clinical feasibility study of Niia demonstrated for the first time ever that the combined offering is, in fact, feasible. It believes its device addresses the need for alternatives to multi-device diabetes management. systems.   Aggregated MARD for the investigational device came in at 11.6%. A MARD target of less than 10% is considered ideal for CGM devices, but PharmaSens said that, in the context of the early feasibility study, the results were encouraging and provide evidence supporting the development of an all-in-one system. https://www.drugdeliverybusiness.com/pharmasens-efs-insulin-patch-pump-cgm/ XX   XX ViCentra launches the newest version of the Kaleido pump system in Europe. This is that small colorful pump, with Diabeloops algorithm and the Dexcom G7. It'll be in Germany and the Netherlands later this summer. https://hellokaleido.com/vicentra-announces-commercial-launch-of-new-smartphone-controlled-kaleido-automated-insulin-delivery-patch-pump-system/--   XX Diabeloop just got CE Mark approval for DBLG2 integrations – it's latest AID platform the company has kicked off the gradual European launch of the technology. It currently offers DBLG2 as a smartphone application on Android, with iOS integration coming soon. As you just heard, it's integrated with kaleido and the company says it plans to make additional configuration for DBLG2 with alternative pumps "available soon." Running on a user's smartphone, DBLG2 works as a self-learning algorithm. It continuously analyzes glucose data, calculates insulin needs in real time and automatically adjusts delivery. https://www.drugdeliverybusiness.com/diabeloop-fda-next-gen-algorithm-g7/   XX Among adults with type 1 diabetes (T1D), the initiation of GLP-1-based therapy was associated with a lower risk for all-cause death, several cardiovascular outcomes, all-cause hospitalisations, and hypoglycaemia, without a higher risk for diabetic ketoacidosis.   METHODOLOGY: Researchers in Greece conducted a retrospective cohort study utilising real-world data from a global health research network to evaluate the association between GLP-1-based therapy and cardiovascular and renal outcomes in adults with T1D. A total of 4088 patients receiving GLP-1-based therapies (median age, 43 years; 34.3% men) were propensity score matched with an equal number of patients not receiving the treatment. The risk for hypoglycaemia was lower with GLP-1-based therapy (hazard ratio, 0.72; P = .021); however, the risk for diabetic ketoacidosis did not differ significantly between the two groups. https://www.medscape.com/viewarticle/glp-1-drugs-tied-cardiovascular-benefits-t1d-2026a1000fbx   XX Eli Lilly and Company (NYSE: LLY) today announced detailed results from two late-phase trials showing that people with obesity maintained their weight loss long term with either Foundayo or lower-dose Zepbound after switching from higher doses of injectable incretin therapy. The findings from SURMOUNT-MAINTAIN and ATTAIN-MAINTAIN, were presented at the 33rd European Congress on Obesity (ECO) and published in The Lancet and Nature Medicine, respectively.   "Weight regain remains one of the biggest challenges in obesity care, and is often the result of treatment interruptions that cause biology to work against patients, undoing the progress they've made," said Louis J. Aronne, M.D., FACP, DABOM, founder and Chair Emeritus of the American Board of Obesity Medicine, former president of The Obesity Society, Fellow of the American College of Physicians, world-renowned obesity specialist and Lilly consultant. "These medicines can be used for long-term maintenance today, and results from SURMOUNT-MAINTAIN and ATTAIN-MAINTAIN provide additional evidence of their potential when switching from higher doses of injectable incretin therapy." https://investor.lilly.com/news-releases/news-release-details/lillys-foundayo-and-lower-dose-zepbound-helped-people-maintain XX Scientists in Sweden have developed a more reliable way to create insulin-producing cells from human stem cells. These lab-grown cells not only respond strongly to glucose but were also able to restore blood sugar control when transplanted into diabetic mice. When transplanted into diabetic mice, the cells gradually restored the animals' ability to regulate blood sugar. Long way to go, as we say with most of these mice studies. https://www.sciencedaily.com/releases/2026/05/260505234620.htm XX Interesting look at how the body controls sugar storage – apparently this finding challenges long-standing biology concepts and could open new directions for disease treatment. Published in Nature, the study describes a potential method for directly reducing glycogen, the stored form of sugar in the body. These scientists discovered that glycogen can be directly regulated by ubiquitin, a protein best known for marking damaged proteins for recycling or removal. The study is the first to show that ubiquitin can regulate glycogen in humans, overturning more than 50 years of scientific understanding. Excess glycogen is also associated with more common health problems, including diabetes, obesity, liver disease, and heart disease.       https://scitechdaily.com/scientists-just-rewrote-biology-hidden-mechanism-could-transform-diabetes-treatment/ XX A new Oklahoma law will give parents the option to have their children screened for Type 1 Diabetes.   The measure passed with overwhelming bipartisan support in the Legislature and takes effect Nov 1. Oklahoma consistently ranks among the states with the highest rates of diabetes and diabetes-related deaths. The law gives parents access to antibody testing that can detect risk years before symptoms develop, helping families take preventive action and avoid emergency room visits. https://journalrecord.com/2026/05/11/oklahoma-law-expands-access-type-1-diabetes-screening/ XX More to come including a new study trying to figure out why some people are more likely to develop diabetes, a look at cannabis and preventing metabolic disorders, and XX   A National Institutes of Health (NIH)-funded study has identified key differences in human pancreatic islet cells that may help explain why some people are more likely to develop diabetes. Researchers found that the mix of hormone-producing cells in the pancreas varies widely from person to person, and that variation plays a central role in how the body regulates blood sugar. The study involved a deep dive into islet cell function that is linked to donor traits associated with observable characteristics, or phenotype, such as sex, race and ethnicity, as well as genetic information, or genotype, including predicted ancestry and genetic risk for both type 1 and type 2 diabetes. The findings highlight that islet cell composition, rather than the physical size and shape of islets, is a key factor in regulating hormone release. The team found that the makeup of pancreatic islets plays a major role in how effectively they release insulin and glucagon — key hormones that regulate blood glucose. Islets with a higher proportion of insulin-producing beta cells showed stronger insulin secretion in response to various stimuli, while higher levels of alpha and delta cells were generally linked to reduced insulin output. In addition, the researchers found that islet hormone secretion is affected by donor traits, such as sex, race and ethnicity and their genetic makeup, including ancestry predicted from genetic testing and genetic risk for type 2 diabetes. Combined, the findings of the study have significant implications for understanding the factors that may predispose people to diabetes. "This study is the tip of the iceberg," said Dr. Evans-Molina. "We hope this dataset becomes useful to the entire diabetes research community and that researchers use it to answer questions about the genotype-phenotype correlation within these data."   https://www.nih.gov/news-events/news-releases/nih-funded-study-maps-human-pancreatic-islet-cells-offering-new-clues-diabetes-risk XX XX XX Research published recently in JAMA Network Open offers illuminating evidence suggesting there is a positive association between GLP-1 agonists—drugs commonly used to treat obesity and diabetes—and better outcomes among breast cancer patients.   "This study suggests that GLP-1 drugs may offer protective benefits potentially improving survival and recurrence risk in some female patients with breast cancer – whether this is related to weight control, improve cardiovascular health or other mechanisms remains to be studied," said study senior author Bernard F. Fuemmeler, Ph.D., MPH, associate director for population sciences and the Gordon D. Ginder, M.D., Chair in Cancer Research at VCU Massey Comprehensive Cancer Center.   Breast cancer patients who are also obese or have type 2 diabetes experience more aggressive cancer growth and worse outcomes. Prior studies have shown that weight loss treatment and surgery following a breast cancer diagnosis are associated with improved heart health and increased survival.   What are GLP-1 drugs? Glucagon-like peptide-1 receptor agonists (GLP-1 RAs). Approved to treat type 2 diabetes in 2005 and weight management in 2021. Impacts on breast cancer survival and recurrence are still unclear. Since 2020, the use of these drugs has increased dramatically, where approximately 12% of Americans have used GLP-1s for weight loss, according to a RAND report.   The research findings Through a retrospective cohort study examining the electronic health records of more than 840,000 breast cancer patients who were diagnosed between 2006 and 2023, the results suggest there is a potential link between GLP-1 RAs and improved outcomes among breast cancer patients who are also obese or have type 2 diabetes.   GLP-1 RA use was associated with an overall lower risk of death from any cause over a 10-year follow-up period among breast cancer patients. Additionally, breast cancer survivors who used GLP1-RAs for diabetes or obesity had a significantly lower risk of their cancer returning over 10 years following their initial treatment.   "Our findings align with emerging preclinical research and contribute to a growing body of literature related to GLP-1 RA use in oncology settings," said study lead author Kristina L. Tatum, PsyD, MS, of the VCU School of Public Health.   What's next? Further studies are needed to understand the biological mechanisms, if any, between GLP-1 RAs and breast cancer outcomes. The research team intends to further evaluate these correlations through randomized clinical trials.   "Our study underscores the potential of GLP-1 RAs as an adjunct strategy for improving cancer-related outcomes among patients with breast cancer, although clinical trials are needed to inform effective therapeutic approaches and clinical decision making," Fuemmeler said. https://www.oncology-central.com/could-glp-1-receptor-agonists-improve-outcomes-for-breast-cancer-patients-with-obesity-or-with-type-2-diabetes/ XX Researchers at UC Riverside gave cannabis to obese mice and found that not only did the rodents lose weight, but when given a concentrated cannabis oil, the mice also saw striking benefits in their metabolic function. DiPatrizio said his team studied the issue to better understand why cannabis users show significant reductions in weight and risk for diabetes compared with nonusers. "We would think that chronic cannabis users would be eating more and weigh more, but it's just the opposite," DiPatrizio said. Scientists are increasingly examining the possibility that cannabis compounds could fight obesity or metabolic disorders like diabetes. Cannabinoids interact with the body's endocannabinoid system, which partially controls nearly every aspect of our physiology, including metabolism and appetite. That creates the possibility that targeting this widespread system could unlock new therapies for these conditions. https://www.sfgate.com/cannabis/article/cannabis-weight-loss-california-study-22255328.php XX A new campaign launched by diaTribe and Genentech aims to empower and educate people about diabetes-related eye disease. Here's what you can do today to protect your eye health. To help address these barriers, diaTribe and Genentech partnered to launch All Eyes on DME, a new campaign that aims to spread awareness and educate people at-risk for or living with diabetes-related eye conditions like DME. Also partnering in the campaign is actor and comedian Damon Wayans, who wanted to share his journey (and, of course, a joke or two) with type 2 diabetes to open up the conversation about what is often a stigmatized or less talked about topic: eye health and diabetes.   One of these important conversations happened recently at the All Eyes on DME launch in New York City, where Wayans joined a panel of experts, advocates, and people living with DME to talk about diabetes-related eye disease and how to help prevent it. https://www.alleyesondme.com/dme-in-the-spotlight.html https://diatribe.org/diabetes-complications/all-eyes-dme-new-campaign-spotlights-eye-health-and-diabetes

Contributor: Travis Barlock, MD Educational Pearls:   Endocannabinoid System: THC binds CB1 and CB2 receptors in neurons and immune cells Δ9-Tetrahydrocannabinol (THC) is the main psychoactive compound in cannabis CB1 and CB2 receptors typically bind endogenously-produced 2-arachidonoylglycerol (2-AG) and anandamide (AEA) to regulate pain, stress, and inflammation THC similarly binds CB1 and CB2, leading to the cannabinoid high: euphoria, paranoia, anxiety, analgesia, anti-inflammation, and appetite, among a variety of others Ingestion via edibles, vice inhalation via smoking, leads to chemical modification of Δ9-THC to 11-hydroxy-Δ9-THC, which more easily crosses the blood-brain barrier and binds CB1 with higher affinity, leading to increased psychoactivity   Cannabinoid Hyperemesis Syndrome (CHS): Chronic THC use leading to the classic presentation of persistent nausea and intense, frequent vomiting Chronic activation of CB1 receptors in brain builds a tolerance and dependence on THC, in addition to chronic activation of the capsaicin and vanilloid receptor TRPV1, which binds capsaicin or is activated by heat Treatment by warm showers works due to TRPV1 activation by heat Treated with benzodiazepines, fluids, and gastro-intestinal or central nervous system agents according to patient presentation   Over 200 synthetic cannabinoids have been created (K2, spice, black mamba, mojo, etc), which are more dangerous and can lead to a variety of etiologies   Acetaminophen binds CB1 receptors to reduce inflammatory pain   References Loganathan P, Gajendran M, Goyal H. A Comprehensive Review and Update on Cannabis Hyperemesis Syndrome. Pharmaceuticals (Basel). 2024;17(11):1549. Published 2024 Nov 18. doi:10.3390/ph17111549  Wall ME, Sadler BM, Brine D, Taylor H, Perez-Reyes M. Metabolism, disposition, and kinetics of delta-9-tetrahydrocannabinol in men and women. Clin Pharmacol Ther. 1983 Sep;34(3):352-63. doi: 10.1038/clpt.1983.179. PMID: 6309462.  Mills B, Yepes A, Nugent K. Synthetic Cannabinoids. Am J Med Sci. 2015 Jul;350(1):59-62. doi: 10.1097/MAJ.0000000000000466. PMID: 26132518. Klinger-Gratz PP, Ralvenius WT, Neumann E, et al. Acetaminophen Relieves Inflammatory Pain through CB1 Cannabinoid Receptors in the Rostral Ventromedial Medulla. J Neurosci. 2018;38(2):322-334. doi:10.1523/JNEUROSCI.1945-17.2017   Summarized by Sam Pahl | Edited by Sam Pahl & Ahmed Abdel-Hafiz, NREMT-P   Donate: https://emergencymedicalminute.org/donate/ Join our mailing list: http://eepurl.com/c9ouHf

In this episode, Justine Reichman interviews Pete Olander, founder and CEO of Happie, a wellness cannabis and hemp beverage brand rooted in California's agricultural legacy. They explore Pete's unconventional journey from finance and NASCAR to plant medicine, the importance of sustainable and organic practices, and the future of cannabis as a functional wellness tool. Keywords Cannabis, Wellness, Sustainability, Hemp, CBD, THC, Functional Beverages, Organic Farming, California Cannabis, Plant Medicine Key  topics Pete Olander's unconventional career path The importance of sustainability and organic practices in cannabis cultivation The role of transparency and storytelling in brand differentiation Sound bites "We use living soil and no till techniques" "Interstate commerce could be a game changer" "The whole category is poised for growth" Chapters 00:00 Introduction to HAPI and Its Founder 01:42 The Unconventional Journey to HAPI 04:11 The Impact of COVID-19 on Wellness Trends 08:46 Ensuring Quality and Integrity in Cannabis Production 11:10 The Future of Cannabis and Interstate Commerce 12:42 Health Benefits of Cannabinoids 18:21 Changing Perceptions of Cannabis as a Wellness Product 20:40 The Evolving Cannabis Market and Consumer Education 25:52 The Product Ecosystem of HAPI 28:01 Crafting New Flavors and Local Sourcing 32:38 Sustainability in Cannabis: Practices and Challenges 39:22 Navigating the Business Landscape of Cannabis 45:47 The Future of HAPI: Growth and Vision

Broadcast from KSQD, Santa Cruz on 5-07-2026: Dr. Dawn debunks the 1971 "220 minus age" maximum heart rate formula, noting a 2025 study found individual predictions were off by up to 20 beats per minute. She recommends the Tanaka equation (208 minus age) times 0.7, but emphasizes tracking improvement trends rather than absolute numbers. ConsumerLab testing found Safe Catch Wild Elite Pure Tuna and Wild Ahi Yellowfin Tuna had no detectable mercury, prompting Dr. Dawn to reconsider eating tuna after years of avoidance due to concerns about mercury bioaccumulation and its effects on nerve microtubules. A meta-analysis of 115 studies involving 55,000 men found limiting ejaculation before IVF leads to increased sperm DNA damage and poorer motility. Clinical trials showed 46% IVF pregnancy rates with less than 48 hours abstinence versus 36% with longer periods. A personalized mRNA vaccine for pancreatic cancer showed striking results: of 16 patients whose tumors were surgically removed, half produced killer T-cells targeting cancer, and seven of those eight remain alive six years later. Pfizer and Valneva's Lyme disease vaccine reduced infection by over 70% in a trial of 9,400 people ages five and up. Nearly half a million Americans contract Lyme annually, and chronic infection can cause nervous system damage and chronic fatigue. Dr. Dawn explores the gray-market peptide ecosystem, where compounds are sold as "research chemicals" with wink-and-nod marketing. A 2018 Belgian study found purity levels ranging from 5% to 99.9%, with some samples containing arsenic, lead, or industrial contaminants. A study of 450 people found that blocking smartphone internet access for two weeks improved sustained attention equivalent to reversing 10 years of age-related cognitive decline, with depression symptom improvements comparable to cognitive behavioral therapy. A multi-country study of 241 unresponsive patients found that 25% showed brain activity indicating consciousness when asked to imagine playing tennis during advanced brain scans. Scientists call this cognitive motor dissociation, and by some estimates tens of thousands of Americans may be misdiagnosed. Chinese researchers grew functional adrenal cortex organoids that responded to pituitary hormones and produced cortisol when transplanted into mice. They also introduced genetic mutations to create organoid models of Cushing's syndrome for drug testing. A Science paper identified the neural pathway connecting psychological stress to eczema flare-ups: sympathetic neurons from the stellate ganglion recruit eosinophils to the skin. Researchers traced the pathway using pseudo-rabies virus injected into skin. Mouse studies showed prenatal stress causes elevated corticosterone in amniotic fluid, which activates fetal mast cells derived from the yolk sac. Offspring develop eczema-like lesions in areas receiving mechanical stimulation, but symptoms resolve around 24 weeks when bone marrow-derived mast cells replace the activated ones. Callers ask about CBN side effects. Dr. Dawn explains cannabinoids prolong anandamide's calming effects by slowing its breakdown, and considers 30-45mg over a night reasonable, but cautions against escalating doses given limited research.

Dr. Anderson graduated from the University of Manitoba in 2011 and finished her residency in Family Medicine, and she is proud to say she is a Metis physician born and raised in Winnipeg, Manitoba, Canada. Dr. Anderson's passion for Cannabinoid medicine started in 2017, when her son with intractable epilepsy had failed all treatments and she was forced to close her practice. Seizing multiple times per hour she knew the outlook was dire, and after one dose of CBD she saw dramatic results. Since then, Dr. Anderson has committed herself to helping other children who have failed all options explore cannabinoids, and she has seen amazing results.

In this expansive conversation with plant alchemist and the founder of Swan Apothecary, Robin Swan, we invite you to try on a new perspective about the healing powers of Cannabinoids. If you are someone who self-medicates with marijuana, is interested in deep treatment with the plant, or have never used it medicinally but you have issues you intuit could be served by proper use and interaction with this plant, Robin has clarity and knowledge to share with you. If you find value in what she shares and you would like to receive consultation or to purchase some of her medicines, please visit Swan Apothecary at https://swanapothecary.com/ and use the discount code SWAN to receive 18% off of your first order.Robin Swan is known for integrating physical, emotional, spiritual, and mental healing into her approach to plant medicine. A passionate advocate for ethical business and patient-centered care, she champions safe cannabis integration and regulatory reform. Guided by her principle “Love All ~ Serve All,” Robin brings a bold, heart-centered voice to the future of hemp and cannabis.Jessica Betancourt is a certified RTT Hypnotherapist and thrice certified Holistic Health Coach. Sessions for hypnosis / coaching combined with the proper and responsible usage of adaptogenic plants can provide profound relief for a variety of root cause issues and symptoms. Come learn more at https://www.therootsofhealthcoaching.com/Be well!! And thank you for being here. ; )Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Der Titel der heutigen Episode lautet: »Die Cannabis-Protokolle«, und mein heutiger Gast ist Stephan Schleim. Er war in Episode 67 im Jahr 2022 schon einmal zu dem Thema Wissenschaft, Hype und Realität zu Gast. Das war und ist eine wichtige Episode, die ich nur empfehlen kann nachzuhören, falls Sie sie verpasst haben sollten. Heute aber geht es um ein seit langer Zeit gesellschaftlich und politisch heiß umstrittenes Thema: Drogen und Abhängigkeit oder Sucht.  Prof. Stephan Schleim ist promovierter Kognitionswissenschaftler, Wissenschaftsphilosoph und hat über 5.000 Studierende im Fach Psychologie ausgebildet, zuletzt als assoziierter Professor für theoretische Psychologie an der Universität Groningen (Niederlande). Zuvor war er Professor für Neurophilosophie an der Ludwig-Maximilians-Universität München. Seit 20 Jahren informiert er auch ein breites Publikum über Fortschritte in Psychologie, Hirnforschung und Psychiatrie, unter anderem in seinem Blog »Menschen-Bilder«. Anlass der heutigen Episode ist sein neues Buch: Die Cannabis-Protokolle. Medizin, Politik und Wissenschaft auf dem Prüfstand. Cannabis wird in dieser Episode ein Thema sein, aber es freut mich, dass wir das Thema Drogen, Abhängigkeit, Substanzen, die Menschen zur Bewusstseinsveränderung nehmen, aber auch Verhaltensweisen, die als Sucht bezeichnet werden, breit angehen. Es handelt sich um ein wirklich relevantes und hochinteressantes Thema, und eines, das perfekt in diesen Podcast passt, denn der Streit um die Frage, was als Droge gilt, was abhängig macht, wie man als Gesellschaft damit umgeht, geht mindestens ins 19. Jahrhundert zurück und wird uns mit Sicherheit noch lange in der Zukunft beschäftigen. Denn der Mensch verwendet seit jeher Substanzen verschiedener Art, um sich zu berauschen, sein Bewusstsein zu verändern sowie in bestimmten sozialen Kontexten und Ritualen. Wo liegt die Grenze zwischen Genuss, Ritual und Sucht? Diese und zahlreiche andere Fragen werden wir in diesem Gespräch thematisieren. Wir beginnen mit der Frage: Was ist eigentlich eine Droge? Woher kommt das Wort, was ist der philosophische und politisch-historische Hintergrund? Wie verändert sich der Begriff über die Zeit? Es gab die erste internationale Verbotsliste beim Opiumkongress in Genf 1925. Was wurde verboten und was waren die Folgen? Zunächst sollten vor allem Opiate verboten werden, aber dann ist durch Gesandte Ägyptens etwas Unerwartetes – was Cannabis betrifft – passiert! So manche Substanz wechselt auch zwischen Arznei und verbotener Substanz hin und her, als Beispiel erwähnen wir Kokain, aber auch Heroin. Wie scharf ist der Drogenbegriff eigentlich? Fallen etwa Substanzen wie Zucker hinein?Woher kommt der Begriff der Pharmazie – pharmakon? Auch in diesem Begriff spiegeln sich die unterschiedlichen Facetten von Substanzen und des Drogenbegriffs wider. Auch Begriffe wie Stimulantien und Genussmittel spielen in dieser Diskussion mit und machen den Diskurs nicht schärfer. Was empfinden wir heute als gefährlich? Hat sich unsere Furcht vor allen möglichen Substanzen ins Extreme gesteigert? Wie viel Eigenverantwortung gestatten wir Menschen noch? Oliver Sacks beschreibt seine Kindheit in England, das Zitat bezieht sich ca. auf die 1940er Jahre: »I had had not the least difficulty getting potassium cyanide from the chemist's, the pharmacy, down the road — it was normally used for collecting insects in a killing bottle — but I could rather easily have killed myself with the stuff. I gathered, over a couple of years, a variety of chemicals that could have poisoned or blown up the entire street but I was careful — or lucky.« — Oliver Sacks Welche Drogen werden in Deutschland und Österreich in welchem Umfang konsumiert? Wie wird (regelmäßiger) Drogenkonsum definiert? Auch die Definition von Drogen ist oftmals enumerativ – also aufzählend –, um das Problem der unklaren Definition zu umgehen. Ist folglich die Drogenpolitik janusköpfig und ist dies überhaupt vermeidbar? Werden psychoaktive Substanzen in den letzten Jahren stärker oder schwächer konsumiert? Und welche Rolle spielen »legale« Arzneien dabei? »In Deutschland hat man inzwischen so viele Antidepressiva Jahr für Jahr verschrieben, dass man fünf Millionen Menschen tagtäglich damit behandeln könnte.«  Das hat sich seit 1990 verelfacht. Wie sieht es mit den verbotenen Substanzen aus?  »Der Anstieg hat schon vor der Teillegalisierung [von Cannabis] angefangen.« Ergeben Verbote Sinn, wenn ein nennenswerter Teil der Bevölkerung diese ignoriert und Substanzen wie Cannabis für viele bereits zum Alltag geworden sind? Hat als Substanz der Wahl (Jugendlicher?) Cannabis Alkohol abgelöst? Ist man mit der Legalisierung zu weit gegangen? Welche Rolle spielt Werbung für pharmazeutische Substanzen (auch Cannabis) – auch da gibt es große Unterschiede zwischen den USA und Europa. Was ist unter diesen Rahmenbedingungen eine »vernünftige« Drogenpolitik, beziehungsweise welche Parameter sollte man hier berücksichtigen? Es gibt wohl einen Unterschied, ob der Konsum einer Substanz im Wesentlichen auf einen selbst wirkt oder andere betrifft, z. B. dadurch, dass der Konsument aggressiv wird oder sein eigenes Verhalten nicht mehr unter Kontrolle hat – denken wir an den Straßenverkehr oder das Verhalten in der Familie. Wie geht man damit um? Was sind positive und negative soziale Faktoren von Substanzkonsum, z. B. Alkohol? Wie sind kulturelle Einflüsse zu bewerten?Cannabinoid- und Opioid-Rezeptoren sind fast über das gesamte Gehirn verteilt – was bedeutet das? Unterschiedliche Opioide überwinden auch die Blut-Hirn-Schranke in unterschiedlichem Tempo, welche Folgen hat dies? »Opioidabhängigkeit ist eine der schwersten Abhängigkeiten – wenn man davon abhängig wird, was auch nicht alle werden.«  Die Frage, wer überhaupt von einer Substanz unter welchen Umständen abhängig wird, ist somit eine hochinteressante Frage für sich selbst. Was ist folglich der Begriff der Sucht? Ist dieser einfacher zu definieren als der Begriff der Droge? Der Effekt ein und derselben Substanz – sei es Alkohol, Opioide oder Cannabis – hat offenbar auf unterschiedliche Menschen sehr unterschiedliche Wirkungen. Was auf manche entspannend wirkt, führt bei anderen zu einer Psychose. Was bedeutet diese Erkenntnis?  »Der Trip, den man erfährt, ist eine Interaktion von Set und Setting.«  Ein Beispiel ist die Nutzung von Heroin durch die US-Soldaten im Vietnamkrieg. Auch außerhalb dieses extremen Szenarios gibt es in unterschiedlichen Subkulturen unterschiedliche Akzeptanz für verschiedene Drogen. Was können wir davon lernen? Damit kommen wir zur Frage, was Abhängigkeit bedeutet und wie diese zustande kommt. Welche Rolle spielt das Über-Verschreiben von Schmerzmedikation durch Ärzte ab den 1990er-Jahren, mit dem Versprechen, Schmerz gehöre der Vergangenheit an und die Gefahr von Schmerzmitteln wäre in der Vergangenheit zum Schaden der Patienten überschätzt worden? »Ein Grund, warum der Konsum so zunimmt, ist meines Erachtens nach auch eine zunehmende soziale Verelendung vieler Gesellschaften.«  Was ist Sucht, was bedeutet der Suchtbegriff? Sowohl in der historischen Betrachtung als auch in der aktuellen Situation? »Vor dem 20. Jahrhundert hat man wenig von Sucht gesprochen.«  Der Psychiater Emil Kraepelin prägte für lange Zeit diese Diskussion. Der Suchtbegriff beginnt sich dann erst langsam zu entwickeln, zum Teil getrieben durch politische und religiöse Überzeugungen. Nach dem Zweiten Weltkrieg wird der Begriff dann durch eine Kommission der Weltgesundheitsorganisation definiert – oder jedenfalls wird der Versuch unternommen. Der Suchtbegriff wird dann durch den Abhängigkeitsbegriff abgelöst. Warum? »Seit den 1980er-Jahren wird der Suchtbegriff in den USA von der Psychiatrie aufgegeben.«  In Deutschland verwenden wir diesen Begriff allerdings permanent. Was bedeutet diese begriffliche Verwirrung in der Praxis? Wie wird also Abhängigkeit – von Substanzen, aber auch Verhalten – definiert? Meist wird Bezug genommen auf Kontrollverlust gepaart mit Dysfunktion. Was bedeutet dies konkret? »Man hat den Konsum nicht mehr unter Kontrolle und der Konsum führt zu verschiedenen Problemen.«  Gibt es einen wesentlichen Unterschied zwischen psychischer und körperlicher Abhängigkeit und fallen Verhaltensweisen in dieselbe Kategorie? Was ist von Begriffen wie Sport-Sucht, Sex-/Porno-Sucht, (Video-)Spiel-Sucht, Arbeits-Sucht usw. zu halten? Was ist der Unterschied zwischen Sucht, Abhängigkeit und Impulskontrollstörung? Ein weiterer Begriff, der sich in diese Melange der oftmals unklar beschriebenen Begriffe mischt. »Man kann auch Sport so betreiben, dass man die Kontrolle verliert und dass er schädlich wird. Im Übrigen hat auch Sport psychische Wirkungen – Runners High. Man könnte eine Sport-Sucht mit den genannten Kriterien definieren. Warum macht man's nicht? Weil Sport moralisch toleriert und gefördert wird.« Was bedeutet das für eine »vernünftige« Drogenpolitik – von libertären Gedanken bis zur Frage, wie mit Schäden an der betroffenen Person und weiter zum individuellen Umfeld und zur Gesellschaft? »Obwohl die Leute immer weniger konsumieren, wird das Thema in den Medien immer extremer diskutiert.«  Freier Markt oder Prohibition? Sollte man den Substanzkonsum kontrollieren? »Substanzkonsum ist etwas Normales.«  Warum wird beziehungsweise wurde der Begriff »Marihuana« fallweise stigmatisierend verwendet? Was ist ein schadenbasierter Ansatz (Harm-based approach)? Welche quantitativen Folgen hatte etwa die (Teil-)Legalisierung von Cannabis in den USA und Deutschland im Vergleich etwa zu Österreich? Sobald es erlaubt ist, ist es für die Jugendlichen weniger anziehend? »Man kann Substanzen nie isoliert betrachten, man muss sich immer auch die soziale Praxis ansehen.«  Verändert sich auch die Droge durch die Nutzung beziehungsweise durch gesellschaftliche Trends? So steigt etwa der THC-Gehalt in Cannabis über die letzten Jahrzehnte stetig (stark) an. Was hat es mit dem viel diskutierten Psychose-Risiko nach Cannabis-Konsum auf sich? »Über Jahrtausende unserer Menschheitskultur war Substanzkonsum in der Regel ritualisiert – entweder mit Freunden oder religiös eingebettet. Wir sind halt im 20. Jahrhundert in diese konsum-, massen- und individualisierte Gesellschaft hineingekommen, die dann eben auch dazu führt, dass manche Menschen diesen ritualisierten oder sozialen Kontext nicht mehr haben.«  Was ist die Rolle von Wissenschaft bei diesen komplexen und wichtigen gesellschaftlich wesentlichen Fragestellungen? »Als Wissenschaftler ist ja meine Funktion nicht, der Gesellschaft zu sagen, wie sie ihre Politik gestalten sollte, aber ich versuche natürlich die Diskussion zu informieren.«  Funktionieren Verbote überhaupt? Sehr viele Probleme erscheinen gerade durch den harten Kampf gegen Drogen erst zu entstehen?! Aber auch die Legalisierung kann man besonders ungeschickt gestalten, wie das gerade auch wieder in Deutschland zu beobachten ist. »Mit Verboten hält man gerade die Menschen mit den größten Problemen nicht ab und erzeugt viele neue Probleme.« Referenzen Andere Episoden Episode 148: Künstliche Vernunft? Ein Gespräch mit Jan Juhani Steinmann Episode 142: Games. A Conversation with Tom Vasel from the Dice Tower Episode 132: Fragen an die künstliche Intelligenz — eine konstruktive Irritation Episode 123: Die Natur kennt feine Grade, Ein Gespräch mit Prof. Frank Zachos Episode 121: Künstliche Unintelligenz Episode 116: Science and Politics, A Conversation with Prof. Jessica Weinkle Episode 111: Macht. Ein Gespräch mit Christine Bauer-Jelinek Episode 107: How to Organise Complex Societies? A Conversation with Johan Norberg Episode 67: Wissenschaft, Hype und Realität — ein Gespräch mit Stephan Schleim Fachliche Referenzen Homepage Stephan Schleim Menschen-Bilder Blog Stephan Schleim, Die Cannabis-Protokolle. Medizin, Politik und Wissenschaft auf dem Prüfstand, BoD (2026) Stephan Schleim, Perspektiven aus der Depressions-Epidemie. Was Depressionen sind und wie man sie behandelt, BoD (2026) Oliver Sacks, Uncle Tungsten, Memories of a Chemical Boyhood, Isis Publishing (2001) International Classification of Diseases 11th Revision, WHO Diagnostic and Statistical Manual of Mental Disorders (DSM-5-TR)

San Fernando Valley OG is one of those strains that doesn't rush you… it settles you.Smooth inhale, calm head, relaxed body, then out of nowhere you realize you've melted into the chair a little more than planned.In this episode, we break down San Fernando Valley OG from Fire Star and how it actually shows up in real life, not just on paper. The flavor leans sour, earthy, a little cheesy on the back end, and surprisingly solid for older flower.What's driving that experience:Terpenes you'll usually see:• Myrcene – that heavy, body-relax feel• Caryophyllene – adds a little spice, helps take the edge off stress• Limonene – keeps your head from going fully foggy• Linalool – soft, calming, slightly floral layerThis combo is why it feels balanced at first… but if you keep going, it leans more into that relaxed, almost sleepy zone.Cannabinoids (typical range):• THC: ~18–24%• CBD: usually very low, often

Marijuana can feel like a miracle fix for ADHD, quieting the noise and taking the edge off. But this short-term relief comes with trade-offs. In this episode, Dr. J breaks down why ADHD brains are drawn to weed, what the research actually says about the long-term consequences, and healthier alternatives. If you've ever wondered whether you're self-medicating, this one's worth your attention. For more on this topic Watch: ADHD and: self-medicating Listen: ADHD and shopping addiction For a transcript and more resources, visit MissUnderstood on Understood.org. You can also email us at podcast@understood.org. Sources: Froude, A. M., Fawcett, E. J., Coles, A., Drakes, D. H., Harris, N., & Soko, J. M. (2024). The prevalence of cannabis use disorder in attention-deficit hyperactivity disorder: A clinical epidemiological meta-analysis. Journal of Psychiatric Research, 171, 48-55. Ryan, J. E., Herens, A., Fruchtman, M., Veliz, P., Kelly, E. L., & Worster, B. (2026). Cannabis use in a community-based sample of adults diagnosed with ADHD: Prevalence, impact on symptoms, and stimulant side effects. Journal of Attention Disorders, 30(3), 407-422. Kaul M, Zee PC, Sahni AS. Effects of Cannabinoids on Sleep and their Therapeutic Potential for Sleep Disorders. Neurotherapeutics. 2021 Jan;18(1):217-227. doi: 10.1007/s13311-021-01013-w. Epub 2021 Feb 12. PMID: 33580483; PMCID: PMC8116407. Suraev, A., McGregor, I. S., Marshall, N. S., et al. (2025). Acute effects of oral cannabinoids on sleep and high-density EEG in insomnia: A pilot randomized controlled trial. Journal of Sleep Research, 34(4), e70124. Chang, Z., Lichtenstein, P., Halldner, L., D'Onofrio, B., Serlachius, E., Fazel, S., ... & Larsson, H. (2014). Stimulant ADHD medication and risk for substance abuse. Journal of Child Psychology and Psychiatry, 55(8), 878-885. Quinn, P. D., Chang, Z., Hur, K., Gibbons, R. D., Lahey, B. B., Rickert, M. E., ... & D'Onofrio, B. M. (2017). ADHD medication and substance-related problems. American Journal of Psychiatry, 174(9), 877-885. Listen to Everyone Gets a Juice Box, a new podcast from Understood.org where host Jessica Shaw has honest talks with parents raising kids who learn and think differently.Understood.org is a nonprofit organization dedicated to empowering people with learning and thinking differences, like ADHD and dyslexia. If you want to help us continue this work, donate at understood.org/give Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

This podcast is made possible by our listeners and viewers. If this show has brought you value, you can support it by becoming a member of The Way Forward, our platform designed to help you find the health and freedom community (people, practitioners, schools, farms, and more) near you. Your membership directly supports the podcast and the work we do.Use discount code THEWAYFORWARD for 10% off Better AromatherapyUse discount code THEWAYFORWARD for 10% off Nature's RootWhat if cannabis has been misunderstood not just culturally, but biologically and environmentally?In this conversation, Dani Fontaine draws on nearly two decades in the cannabis and hemp industries, where she's built companies, developed therapeutics, and led innovation in plant-based wellness. Her work ranges from creating hemp-derived body care and nutritional products to founding a terpene-focused aromatherapy company and the first hemp-based spa, all rooted in a broader view of sustainable health.We get into how epigenetics reframes the idea that genetics are fixed, and why expression is constantly shifting moment to moment. Dani explains how cannabinoids, terpenes, and other plant compounds influence cellular communication, and why focusing only on THC misses the larger picture.This conversation opens up a deeper look at coherence in the body, the role of plant intelligence, and how understanding your biological blueprint can change how you approach healing.You'll learn:[00:00] Introduction[08:18] What cannabis represents, and why it was buried by corporate interests[15:21] How THC is chemically turning men into passive, apathetic versions of themselves[22:44] When Dani got started, and the stage-four cancer patient who changed everything[31:17] The body's master balancing system, and why medicine never told you about it[53:06] Why 85% of people shouldn't use THC, and what it does to the ECS long-term[01:00:09] Cannabis, the big C, and how the plant houses every terpene on earth[01:21:59] How to rebalance your endocannabinoid system with Dani's 90-day protocol[01:37:44] Why the ECS is the master controller of everything happening inside your cells[02:05:30] Pain, somatic work, and the cannabis products built to go deeperRelated The Way Forward episodes:The 4th Phase of Water: The Blueprint for Biological Energy with Dr. Gerald Pollack | YouTubeResources mentioned:The Fourth Phase of Water: Beyond Solid, Liquid, and Vapor by Gerald Pollack | Book or AudiobookFind more from Dani:Dani Fontaine | InstagramMainspring Well Center | WebsiteBetter Aromatherapy | WebsiteNature's Root | WebsiteFind more from Alec:Alec Zeck | InstagramAlec Zeck | XThe Way Forward | InstagramDonate to The Way Forward here.The Way Forward is Sponsored By:Eating well shouldn't be complicated. Dr. Cowan's Garden makes it simple to increase your daily nutrient density with their signature vegetable powders, clean pantry staples, and pasture-raised products. Family-run and committed to "beyond-organic" quality.* Offer: Use code THEWAYFORWARD for 15% off your first order.* Shop: Dr. Cowan's GardenPACHA Sourdough: The wheat-free, sprouted buckwheat bread that actually digests well. Made with just two ingredients: organic sprouted buckwheat and sea salt. No gums, oils, or fillers.* Discount: Use code THEWAYFORWARD for 10% off.* Shop: Live PachaPaleoValley: 100% Grass-Fed Bone Broth Protein is a nutrient-dense, easy-to-digest source of collagen and essential amino acids. Sourced from grass-fed cows, this protein powder provides the building blocks for healthy joints, skin, and gut function—without fillers or artificial ingredients. Support the show and claim 15% off your PaleoValley order!

Neurodivergence and weed. Munchie remedies. Long term toking. The Entourage Effect. Drag a bean bag into the circle and kick back for Part 2 of Cannabinology with UCLA's Center for Cannabis and Cannabinoids director Dr. Ziva Cooper and Smith College cannabis anthropologist Dr. Caroline Melly. We'll probe the great mystery and misfortune of hyperemesis, the effect of THC on memory and neuroplasticity, why edibles sometimes send you to a distant galaxy, CBD and inflammation, the risks of psychosis, older vs. younger brains and cannabis, a guy named Rick Simpson, how much weed is the right amount of weed, and if any studies warrant further research. Heads up: they do.   Follow Dr. Cooper on Google Scholar   Visit the UCLA Center for Cannabis and Cannabinoids website   Follow Dr. Melly on Google Scholar A donation went to Last Prisoner Project More episode sources and links Other episodes you may enjoy:Psychedeliology (HALLUCINOGENS), Dolorology (PAIN), Mnemonology (MEMORY), Attention-Deficit Neuropsychology (ADHD), Molecular Neurobiology (BRAIN CHEMICALS), Addictionology (ADDICTION), Neuropathology (CONCUSSIONS), Neuropathoimmunology (MULTIPLE SCLEROSIS), Salugenology (WHY HUMANS REQUIRE HOBBIES), Obsessive-Compulsive Neurobiology (OCD), Quasithanatology (NEAR-DEATH EXPERIENCES), Oneirology (DREAMS) 400+ Ologies episodes sorted by topic Smologies (short, classroom-safe) episodes Sponsors of Ologies Transcripts and bleeped episodes Become a patron of Ologies for as little as a buck a month OlogiesMerch.com has hats, shirts, hoodies, totes! Follow Ologies onInstagram andBluesky Follow Alie Ward onInstagram andTikTok Editing by Mercedes Maitland ofMaitland Audio Productions andJake Chaffee Managing Director: Susan Hale Scheduling Producer: Noel Dilworth Transcripts by Aveline Malek Website byKelly R. Dwyer Theme song by Nick Thorburn Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

This week primary care physicians Kate Rowland, Mark Ebell, Gary Ferenchick and Henry Barry tackle 4 new POEM-worthy studies: new therapy for elevated triglycerides, cannabinoids for chronic pain in adults, the best antithrombotic for patients with AF + drug eluting cardiac stent, and lower versus standard LDL targets for patients with heart diseaseEssential Evidence Plus: https://www.essentialevidenceplus.com/ Lower triglycerides: https://pubmed.ncbi.nlm.nih.gov/41211918/Cannabinoids for pain: https://pubmed.ncbi.nlm.nih.gov/41429020/ Antithrombotics for AF + stent: https://pubmed.ncbi.nlm.nih.gov/41211917/ LDL target 55 vs 70 for CAD: https://pubmed.ncbi.nlm.nih.gov/41910315/

Gummies vs. pre-rolls. THC vs. CBD. Indica vs. sativa. Hemp vs. marijuana. Dad grass vs. modern trees. This extended 2-part deep dive with UCLA's Center for Cannabis and Cannabinoids director Dr. Ziva Cooper and Smith College cannabis anthropologist Dr. Caroline Melly covers the storied history of the weed's trek across continents, the endocannabinoid system,  the “bliss” molecule, brain receptors, cancer therapeutics, edible mishaps, the munchies, legalization, titration, addiction, kief, hash, dabs, shatter, strains, and so much more.  Follow Dr. Cooper on Google Scholar Visit the UCLA Center for Cannabis and Cannabinoids website Follow Dr. Melly on Google Scholar A donation went to Last Prisoner Project More episode sources and links Other episodes you may enjoy: Psychedeliology (HALLUCINOGENS), Dolorology (PAIN), Mnemonology (MEMORY), Attention-Deficit Neuropsychology (ADHD), Obsessive-Compulsive Neurobiology (OCD), Molecular Neurobiology (BRAIN CHEMICALS), Traumatology (PTSD), Somnology (SLEEP), Eudemonology (HAPPINESS), Neuropathology (CONCUSSIONS), Neuropathoimmunology (MULTIPLE SCLEROSIS), Sports & Performance Psychology (ANXIETY & CONFIDENCE), Addictionology (ADDICTION), Salugenology (WHY HUMANS REQUIRE HOBBIES),  Quasithanatology (NEAR-DEATH EXPERIENCES), Oneirology (DREAMS) 400+ Ologies episodes sorted by topic Smologies (short, classroom-safe) episodes Sponsors of Ologies Transcripts and bleeped episodes Become a patron of Ologies for as little as a buck a month OlogiesMerch.com has hats, shirts, hoodies, totes! Follow Ologies on Instagram and Bluesky Follow Alie Ward on Instagram and TikTok Editing by Mercedes Maitland of Maitland Audio Productions and Jake Chaffee Managing Director: Susan Hale Scheduling Producer: Noel Dilworth Transcripts by Aveline Malek  Website by Kelly R. Dwyer Theme song by Nick Thorburn Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

You probably had a psychoactive drug today and didn't even realize it. In this Jack Westin MCAT Podcast episode, Mike and Molly break down every major class of psychoactive drugs you need to know for the MCAT, including how each one hijacks your synapses, which neurotransmitters are involved, and why some are incredibly addictive.Next episode: Magnetism and how MRIs actually workGet started with our resources!

On this episode of the Bioactive Podcast, Dr. Riley Kirk is joined by Dr. Codi Peterson and Megan Mbengue to discuss their newly published paper on Cannabinoid Hyperemesis Syndrome (CHS). Drawing from their recently published research and clinical experience, they explore what CHS is, how it presents, and why it is often misunderstood or misdiagnosed. The conversation covers early warning signs, the prodromal phase, and the severe symptoms patients experience, including the challenges faced in emergency care settings. They also address common misconceptions around cannabis use patterns, frequency, and the role of THC in the development of CHS. They discuss key factors influencing CHS, including consumption methods such as vaping versus flower, rapid THC absorption, tolerance, and the impact of high-potency products. The discussion explores myths around pesticides, synthetic cannabinoids, and the importance of distinguishing correlation from causation in cannabis-related health outcomes. Additionally, they examine strategies for reducing risk, including tolerance breaks, balanced use, and patient education without stigma. The dialogue further highlights the importance of compassionate care, proper diagnosis, and the role of healthcare professionals in bridging the gap between cannabis use and medical understanding. Finally, they touch on future research directions, the importance of data collection, and how education can shape safer, more informed cannabis use. This is a conversation for anyone using cannabis regularly, healthcare professionals seeking to better understand CHS, or patients navigating unexplained symptoms. Whether you're exploring cannabis for wellness or working in clinical settings, this episode provides critical insight into responsible use, early warning signs, and the evolving science behind cannabis-related health outcomes. Chapters 00:00 CHS Is Real 00:58 Welcome And Guests 01:43 Publishing The Study 03:47 What Is CHS 05:04 ER Reality Check 06:17 Scromiting And Severity 09:16 Survey Size And Reach 10:48 Vapes Versus Flower 11:42 Use Patterns And Myths 15:55 Prodrome Phase Warning 18:13 Triggers And Cutting Down 23:41 Is THC The Culprit 26:06 Why Vapes Hit Faster 27:56 Vaping And THC Spikes 29:22 Pesticides Myth Busting 31:57 Tolerance Breaks And Balance 34:08 CHS Education Not Stigma 36:45 ER Diagnosis And Overdiagnosis 38:55 Who Gets CHS Demographics 41:22 Early Warning Signs 43:28 Synthetic Cannabinoid Risks 45:37 Whole Plant Over Isolates 50:02 Future Papers And Next Steps 51:57 Compassion And Closing Read the Research on CHS Cannabinoid Hyperemesis Syndrome Publication: https://journals.sagepub.com/doi/10.1177/25785125261421434?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed Note: This publication is currently behind a paywall but will be available for free on Patreon. Sponsor Thank you to our sponsor Storz & Bickel! S&B makes medical-grade dry herb vaporizers which are some of my favorite products to use daily. If you want to check them out, head to storz-bickel.com and use code Riley10 for 10% off most items! Want Exclusive Content and Ad-Free Episodes? Join the Bioactive Patreon community for as little as $1/month to ask guests your burning questions, access exclusive content, and connect with Dr. Kirk one-on-one. www.Patreon.com/Cannabichem

We look at 5 recent publications in the field of toxicology.1.      Helander A, Andersson A, Villén T. Origin and Interpretation of Low Methamphetamine Levels Found in Amphetamine-Positive Urine Samples: Support for Methylation of Amphetamine as a Minor Metabolic Pathway. Drug Test Anal. 2025;17(11):2276-2282. doi:10.1002/dta.39402.      Labay LM, Midthun KM, Kacinko SL, Papsun DM. Drug identification in biologicals on clothing, bedding, and other materials. J Anal Toxicol. 2025;49(8):603-608. doi:10.1093/jat/bkaf0573.      Ogawa S, Shiraki R, Wakigawa K, et al. Quantitative analysis of ethylene glycol in human serum by liquid chromatography-tandem mass spectrometry with p-toluenesulfonyl isocyanate derivatization. Forensic Toxicol. 2026;44(1):37-46. doi:10.1007/s11419-025-00729-04.      Ballotari M, Truver MT, Sojin NA, et al. Analysis of cannabinoids and semi-synthetic cannabinoids in authentic breastmilk samples by liquid chromatography-tandem mass spectrometry. J Anal Toxicol. 2025;49(8):559-566. doi:10.1093/jat/bkaf0475.      Grafinger KE, Weinmann W, Pasin D, et al. Machine learning in forensic toxicology: Concepts, applications and challenges in bioanalysis, ADME, and toxicodynamics. Forensic Sci Int. Published online February 9, 2026. doi:10.1016/j.forsciint.2026.112883Contact us at toxpod@tiaft.orgGet free open access journal articles at https://forensiclibrary.org/homeYou can send us a text message using this link!

On this episode of Vitality Radio, Jared dives deeper into the practical side of hemp products—how to use CBD, THC, and other cannabinoids wisely and responsibly.This conversation explores real-world application: when CBD isolate makes sense, why small amounts of THC can enhance results, and how the entourage effect influences the way cannabinoids interact with the body. Jared explains the role of the endocannabinoid system and how lifestyle factors can support this system naturally. You'll also hear practical strategies for stacking hemp products with nutrients like magnesium, herbs, and other supportive formulas for stress, sleep, and recovery. This episode provides a balanced, educational look at hemp as a botanical tool—emphasizing thoughtful use, quality sourcing, and individualized approaches to supplementation.Products:CBD Products - Visit Vitality Nutrition in Bountiful, Utah or call us to inquire and order 801-292-6662Vital SleepMagnesium BisglycinateAnxiety ReleaseTen Days of SunshineOmega-3Curamed Acute PainOllois Cold and Flu Kit (Vitality Radio POW! Product of the Week 30% off of the sale price with PROMO CODE: POW31)Additional Information:#619: Is CBD About to Be Banned? The Future of Hemp In America with Maggie FrankU.S. Hemp Roundtable#375: A Comprehensive Approach to Chronic Pain with Maggie Frank#415: Q&A Show #1 - Jared Answers Your Questions About CBD, Daily Values, Prebiotics, and More!#250: The Key Supplements You Need to Fight Anxiety and Depression with Stuart Tomc#186 The Powerful Effect of 10:1 ratio CBD + THC with Stuart TomcVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

Dr. Mohsin Maqbool is a pediatric neurologist and sleep specialist based in Dallas–Fort Worth, Texas. His work focuses on the intersection of neurodevelopment, sleep, and cannabinoid therapeutics in autism spectrum disorder. He is particularly interested in how cannabinoid formulations may influence sleep regulation, behavior, and quality of life in children with autism. At CannMed 26, Mohsin will present “Autism, Sleep, and Medicinal Cannabis: Evaluating 18-Month Efficacy and Safety Outcomes” During our conversation, we discuss: The gaps in current sleep medicine for children with Autism Spectrum Disorder Results from Mohsin's 18-month longitudinal study including improvements to total sleep time, sleep onset and maintenance, and overall quality of sleep The method of finding the effective dose for each patient  Cannabinoids' effect on the duration of REM sleep and what the daytime implications are  Thinking of cannabis as a tool to supplement conventional ASD medications and not a replacement  Future research directions – using wearables and EEG to investigate how cannabinoids affect sleep architecture and brain physiology, as well as using biomarkers to see whether patients are a good candidate for cannabinoid therapies Thanks to This Episode's Sponsor: The Society of Cannabis Clinicians  The Society of Cannabis Clinicians is a nonprofit professional association of physicians and other healthcare providers. It provides continuing education—for clinicians, patients, and all concerned about the medical use of cannabis and best practices in clinical care. SCC physicians have been monitoring cannabis use by patients for 20 years and have compiled a wealth of clinical evidence and treatment strategies that will be validated by clinical trials in the years ahead. To learn more about SCC and to join visit cannabisclinicians.org. Additional Resources Effects of Medical Cannabis Treatment for Autistic Children on Family Accommodation: An Open-Label Mixed-Methods Study [Book] Cannabis Is Medicine: How Medical Cannabis and CBD Are Healing Everything from Anxiety to Chronic Pain by Dr. Bonni Goldstein Register for CannMed 26 Meet the CannMed 26 Speakers Review the Podcast CannMed Archive

There are many things that can impact your ability to become pregnant. In today's episode, I'm reviewing the top 10 things to consider if you are TTC.    1. Environmental Toxins. Avoid microwaving food in plastic containers or bottles. Always store food and glass or stainless steel containers. Million Marker offers a test to find out if you have in-body toxicity. 2. Chemicals in food and everyday products. Verify that the products you are using are chemical free. You can do that on https://www.ewg.org/ 3. Being sedentary. The CDC and American College of OBGYN, both recommend exercise in amounts of 150 minutes per week. Avoid over exercising, as low BMI can also cause fertility issues. 4. Food allergies or intolerances. Work with a nutritionist to find out if you have a food allergy or other food intolerance. You may also want to consider working with a specialist if you have PCOS or working with a nutritionist like Rohini Bajekal to help you manage PCOS if you have it. 5. Blocked Fallopian Tubes. Check with your doctor to find out if this is what may be causing you to have a hard time TTC. 6. THC and Cannabinoids can affect the motility of the fallopian tube and the receptors in the lining of the uterus. This makes embryo implantation harder and it might not happen as quickly as you would want. 7. Nicotine. Nicotine can affect the DNA and the egg in the sperm cells, and it can also affect a woman's fertility such that she could go potentially into menopause earlier. 8. Blaming birth control pills. Many people think that birth control pills "cause" infertility, but the truth is that because they regulate your period they may be masking the indicators of infertility. Make sure you get your hormone levels checked with your doctor every year to confirm your levels.  9. Ignoring biology. Every woman is born with a finite number of eggs, and if you want to wait to have kids until later in life, be sure and freeze your eggs when you are in your 20s.  10. Not getting enough sleep.    Listen on Dr. Aimee's website.   Curious about IVF? Click here to join Dr. Aimee for The IVF Class. The next live class call is on Monday, March 9, 2026 at 4pm PST, where Dr. Aimee will explain IVF and egg freezing and there will be time to ask her your questions live on Zoom.   Dr. Aimee Eyvazzadeh is one of America's most well known fertility doctors. Her success rate at baby-making is what gives future parents hope when all hope is lost. She pioneered the TUSHY Method and BALLS Method to decrease your time to pregnancy. Learn more about the TUSHY Method and find a wealth of fertility resources at www.draimee.org.

Itch is a common and often frustrating symptom that presents to the dermatology clinic. Adam Friedman, MD provides updates on emerging management strategies while Joe Gorelick, MSN, FNP-C shares tips for documenting itch--and its improvement. Plus, Gilly Munavalli, MD gives the skinny on GLP-1s and their effects on the face, and Brad Glick, DO discusses intralesional injections for nails.Like what you're hearing? Want to learn more about the Dermatology Education Foundation? Explore assets and resources on our website.

Did you know optimized sleep can transform your days by: ✅ Processing emotions & repairing your body overnight ✅ Waking up energized & clear-headed (no grogginess) ✅ Reducing stress, anxiety & evening wine cravings ✅ Supporting mood, hormones & long-term vitality In this episode, I sit down with Joseph Sheehey, former NASA engineer & founder of Cured Nutrition, to unpack cannabinoids for better rest. We clarify CBD, CBN, microdose THC, full-spectrum hemp — and why quality + herbal synergy make all the difference. Key highlights: Why sleep is essential for emotional processing, recovery & vibrant energy. CBD for calm, CBN for deep "weighted blanket" relaxation, microdose THC for gentle relief without impairment. How Cured's adaptogen-blended gummies outperform typical dispensary options (no paranoia, restored mornings). Joe's journey from depression & near-suicide to building a natural healing brand. The 2025 hemp regulation changes & what they mean for wellness-focused products. Ready for deeper, more restorative sleep? Visit HayleyHobson.com/cured — use code HAYLEY for 15% off (details in show notes). Resources: Shop & discount: HayleyHobson.com/cured (code: HAYLEY) Advocacy info: NCRCA.us Full transcript: Hayley Hobson's Podcast Connect: Instagram • Facebook • TikTok — subscribe for weekly tools to a 10/10 life. Share this with anyone struggling with sleep — and leave a review to help more women find it!

Dr. Codi Peterson is a pediatric pharmacist with over a decade of experience specializing in acute care and pediatric emergency medicine. He currently serves as a clinical pharmacist at Rady’s Children’s Health of Orange County, where he works night shifts in the Emergency Department and applies his expertise to optimize medication safety and therapeutic outcomes in children. Beyond the hospital, Codi is deeply committed to education and mentorship. He is an Associate Clinical Professor at the University of California, Irvine, where he teaches cannabis pharmacology and therapeutics, and a guest lecturer at OCEMT, instructing paramedics and firefighters in applied pharmacology. He is also an active researcher on Cannabinoid Hyperemesis Syndrome (CHS), having led one of the largest patient surveys on the condition to date. At CannMed 26, Codi will share the results of that study in a presentation titled, “Through the Eyes of a Patient: Integrating Story and Science to Demystify CHS”.  During our conversation, we discuss:  Defining CHS and explaining why it is difficult to research  Cannabis use patterns among CHS sufferers  Whether contaminants and pesticides play a role in developing CHS  The prodromal phase and early warning signs of CHS  Sex-based differences in CHS patients  Understanding the biological mechanisms behind the development of CHS  and more Thanks to This Episode’s Sponsor: The Cannigma  The Cannigma takes an evidence-based approach to cannabis content – from safety to cooking to medical research – and makes all the information digestible and useful. They are committed to making sure scientific information is accessible to anyone who needs it – be it to relieve their own suffering or that of a loved one, to learn a bit more, or even just for fun.  Learn more at cannigma.com  Additional Resources Surveying Cannabinoid Hyperemesis Syndrome Patients with Megan Mbengue and Codi Peterson [Video] Cannabinoid Hyperemesis Syndrome What You Need to Know [Video] what-is-chs.com Connect with Codi (Instagram, LinkedIn) The Cannigma Register for CannMed 26 – Early Bird Ends February 20th!

Send us a textThe FDA is facing a deadline next week to publish three federal cannabinoid lists and to clarify what counts as a hemp product “container” under appropriations legislation President Donald Trump signed last year. Those lists and the “container” guidance are due by Tuesday, and they matter because the law is scheduled to change federal hemp rules in November—shifting from a delta-9 THC standard to “total THC” (including delta-8 and other isomers) and potentially restricting a wide range of consumable cannabinoid products.00:00 Welcome and Episode Overview00:59 Super Bowl Sunday Vibes01:36 FDA's Upcoming Deadline on Hemp Definitions03:38 Hemp Industry and Legal Confusion08:43 Cannabis and Hemp Policy Roundtable12:53 New Member Shoutouts and Upcoming Content13:54 Legal Challenges and Market Dynamics26:29 Dispensary Tour and Regulations28:04 State Security Regulations28:41 Building Renovations and Compliance29:08 Cannabis Legalization and Regulations29:46 Logo Contest and Compliance Challenges31:05 Federal Security Clearances and Cannabis32:09 Cannabis and Holistic Wellness32:54 Cannabis Industry and Legalization Challenges40:50 Minnesota Cannabis Raid and Legal Battle42:04 Cannabis Strain Review45:28 Oklahoma's Black Market Crackdown50:58 Ohio's Antitrust Lawsuit Against MSOs55:31 Final Thoughts on Cannabis Policy#CannabisNews #Hemp #FDA #THC #CBD #Delta8 #FarmBill #Cannabinoids #CannabisLegalizationwant to start your own podcast?  Try StreamYard.Want to create live streams like this? Check out StreamYard: https://streamyard.com/pal/d/5822037327085568Support the showGet our newsletter: https://bit.ly/3VEn9vu

Dr. Beth Weise is the Research and Overdose Prevention Coordinator for The Sidewalk Project, a non-profit organization that aids unhoused, drug-using, survivor & sex worker populations by providing direct services including crisis response, system advocacy, wound care, job placement, medication-assisted treatment (MAT), and creative community resources for mental health. Her work aims to influence future drug policy with novel evidence-based research that also advocates and empowers people who use drugs to feel safe and prevent fatal overdose. At CannMed 26, Beth will present “Cannabidiol to Mitigate Opioid Induced Respiratory Depression“. During our conversation, we discuss: What causes Opioid Induced Respiratory Depression and how cannabinoids play a role How CBD can be used in combination with Naloxone to reduce withdrawal-related side effects How Beth's research can be applied in real-world scenarios Thanks to This Episode's Sponsor: Humanity Heroes Humanity Heroes provides compassionate support to the unhoused community by delivering essential supplies and resources directly to those in need. Humanity Heroes partners with other nonprofits by empowering them to extend their reach and impact within their own communities. Together, they strive to create a world where every person has access to the resources and support they need to thrive. Learn more at JoinHumanityHeroes.org Additional Resources: THRRIV.org [Webinar] Bridging the Gap: Tech-Supported Peer Connections to Reduce – Overdose Fatalities – Register for CannMed 26

In this episode of the Bioactive Podcast, Dr. Hemant Bid joins Dr. Riley Kirk discussing the often-overlooked world of acidic cannabinoids aka Raw or Unactivated cannabinoids, such as CBGA, THCA, and CBDA. He shares his extensive background in cannabis research and education, emphasizing the therapeutic potential of these compounds, which are non-psychoactive and interact with various non-cannabinoid targets in the body. The conversation also delves into extraction techniques for preserving these cannabinoids, their role in plant defense, and the future of research in this area. Dr. Bid highlights the importance of personalized medicine and the need for more education and understanding in the field of medical cannabis. Join the Bioactive Patreon community for as little as $1/month to ask guests your burning questions, access exclusive content, and connect with Dr. Kirk one-on-one.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ www.Patreon.com/Cannabichem⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Stress feels louder, sleep feels harder, and your nervous system is fried. Welcome to midlife! In this episode, Joe Sheehey, founder of Cured Nutrition, breaks down the endocannabinoid system, how it impacts stress and sleep, and why it matters even more for women 35+. We also dive into exactly how to tinker with CBD, CBN, and microdosing THC in a practical, science-based way. No hype or overselling, just tools you can use in everyday lifeTimestamps:[1:38] Intro[6:15] Welcome Joe - can you break down the differences between CBD, CBN, and THC in practical terms?[11:20] Tell me more about the  cannabinoid system and how supplementation actually works.[14:58] Is there any literature that shows that people become deficient in cannabinoids? [15:50] Talk to me about CBN[20:57] Is there a difference the way men respond vs women?[22:49] If somebody sees the product and it has THC in it, talk to me about the dosing. What is a microdose? What do you see to be most effective?[28:27] For women who are 35 years old, where does THC shine? Is it more about the relaxation or in how you deal with your daily stress? Are we taking it every day? Do you become dependent on it? Talk to me about it.[33:44] What are the biggest mistakes people make when trying to teach or even micro using it for the first time?[36:11] If somebody is really struggling with their sleep, would you recommend they just try CBD or just try CBN or do you think they should try a combination of everything?[39:55] How does CBN differ from melatonin or magnesium?[43:50] Do you find that people who practice healthier lifestyles that cannabinoids  work more effectively and they need less of it?[58:19] What would you say to the person who said CBD or CBN did not work for me?[1:05:14] For the salve, how does it work to target the pain? Episode Links:Curednutrition.com/wellfed for 20% off your orderSerenity GummiesCalm CapsZen CapsSalveFollow Joe on InstagramThe Journal of Neuropsychopharmacology Article Article Summary:The study you are likely referring to is a 2021 clinical trial conducted by researchers at Johns Hopkins Medicine, published in the journal Neuropsychopharmacology.This study is significant because it identified a "sweet spot" dose for THC (specifically 2.5 mg) that could provide therapeutic benefits (pain relief) without the negative intoxicating effects or "high" associated with larger doses.Sponsors:Go to https://thisisneeded.com/  and use coupon code WELLFED for 20% off your first order.Go to drinklmnt.com/wellfed and use code WELLFED to get a free 8-pack with any drink mix purchase!Go to http://mdlogichealth.com/wfcolostrum, and use coupon code WFC15 for 15% off. You can also use code WELLFED for 10% off site wide on all MD Logic Products. Go to wellminerals.us/vitaminc and use code WELLFED to get 10% off your order.

https://www.mdpi.com/1420-3049/28/2/833?utm_source=chatgpt.com#Materials_and_MethodsLink to article we discuss at the start of the show, titled "Comparison of the Cannabinoid and Terpene Profiles in Commercial Cannabis from Natural and Artificial Cultivation"This week host @Jackgreenstalk (aka @Jack_Greenstalk on X/instagram backup account) [or contact via email: JackGreenstalk47@gmail.com] is joined by panel with @spartangrown on instagram or X f.k.a. Twitter at https://x.com/grown43626 or email spartangrown@gmail.com for contacting spartan outside social media, any alternate profiles on other social medias using spartan's name, and photos are not actually spartan grown be aware, and and @TheAmericanOne on youtube aka @theamericanone_with_achenes on instagram who's amy aces can be found at amyaces.com .... This week we missed Rust Brandon of @fulcrop.sciences / fulcrop.ceo regained @Rust.Brandon instagram page, and products can be found at bokashiearthworks.com, and @NoahtheeGrowa on instagram, Matthew Gates aka @SynchAngel on instagram and twitter @Zenthanol on youtube who offers IPM direct chat for $1 a month on patreon.com/zenthanol , @drmjcoco from cocoforcannabis.com as well as youtube where he tests and reviews grow lights and has grow tutorials and @drmjcoco on instagram and @ATG Acres Aaron The Grower aka @atgacres his products can be found at atgacres.com view his instagram to find out details about drops!

In the summer, we told you the story of Jill Fuller. She developed Cannabinoid Hyperemesis Syndrome after replacing a glass of wine at night with THC gummies for months. CHS is a condition characterized by persistent nausea and vomiting, intense abdominal pain and loss of appetite. As the condition gains attention on social media, WRAL health reporter Grace Hayba revisits what it looks like, what causes it and updates us on how Jill is doing.

It's This Week in Bourbon for December 19th 2025. Cannabinoid regulation is underway, a trial using a robotic dog with an ethanol sensing system is launched, and Wilderness Trail Distillery has announced the limited-edition release of a 10-Year Wheated Bourbon.Show Notes: The Cannabinoid Safety and Regulation Act (CSRA) establishes a strict federal framework for hemp-derived products President Trump reportedly planning executive order to reclassify marijuana to Schedule III status Uncle Nearest CEO Fawn Weaver issues apology following "dismissive" out-of-context video encounter Benson Valley Bourbon joins Kentucky Distillers' Association as newest craft level member Bourbon on the Banks Festival awards over $100,000 to local nonprofits from 2025 proceeds Bacardi trials autonomous "Royal Bark-la" robot dog to detect Scotch warehouse leaks Garrison Brothers announces December 6 release of 2025 Cowboy Bourbon at $249.99 Four Roses launches 375ml Small Batch and Small Batch Select bottles nationwide Wilderness Trail debuts limited 10-Year Wheated Bourbon for Wilderness Road 250th anniversary Heaven Hill announces Fall 2025 Old Fitzgerald 11-Year-Old Bottled-in-Bond decanter release Learn more about your ad choices. Visit megaphone.fm/adchoices

Dr. Hoffman continues his conversation with Maggie Frank, the national educator for CV Sciences, makers of PlusCBD Oil.

Exploring the Benefits and Science of CBD and Canna Mimetics with Expert Maggie Frank, the national educator for CV Sciences, makers of PlusCBD Oil. She has a deep-dive into the latest updates on CBD (cannabidiol) products, their benefits, and distinctions from THC (tetrahydrocannabinol). Frank explains the endocannabinoid system and how phytocannabinoids like CBD can help achieve homeostasis in the body, aiding in stress management, inflammation, and gut health. They discuss the nuances of different cannabis plants, the current landscape of CBD research, and the misconceptions around THC use. Additionally, Maggie introduces some innovative CV Sciences products, including those that do not contain CBD but offer similar benefits through canna mimetics—natural compounds that mimic the effects of cannabinoids. Among these products are a focus-enhancing gummy and a metabolic support formulation called ReShape. They also touch upon upcoming legislation and how it impacts the hemp industry. The discussion highlights the broad-spectrum potential of CBD and related compounds in promoting overall health and addressing various conditions.

Clinicians should weigh benefits against risks when engaging patients in informed discussions about cannabis or cannabinoid use. Kevin Hill, MD, MHS, of Harvard Medical School joins JAMA Senior Editor Karen Lasser, MD, MPH, to discuss the current evidence about the therapeutic use of cannabis and cannabinoids in adults, potential harms, and evidence-based clinical guidance. Related Content: Therapeutic Use of Cannabis and Cannabinoids

Cannabinoid and mTBI

It's the Soapbox Edition of the Adam Dunn Show and the lines are open ! The industry was reminded how fragile and fragmented it is. Slipped into the reopening of the government was an amendment that would clarify the definition of hemp to ban all hemp-derived products containing THC, which were legalized by the 2018 farm bill. Legal hemp products are limited to a total of 0.4 milligrams per container of total THC, or any other cannabinoids with similar effects. Cannabinoids that are synthesized or manufactured outside the plant, like delta-8 THC, are outright banned. There's a lot to unpack here and there's as much good as bad, we hardly need every gas station selling Terp infused prerolls or no oversight in manufacturing of edibles but at the same time we NEED to protect the hemp farmers that are producing cbd for salves , tinctures etc that really help patients in those unregulated states. Joining us in studio we have Brett from @heartandsoilproject seeds and nutrients based here in Colorado Brett has dived deep in the organic pool and puts his $ where his mouth is. Whether is organic farming or raising livestock, Brett gives it his 100%. …….So get that @dabx GO rig charged your @jerome_baker bong Clean with some ice

Dr. Anderson graduated from the University of Manitoba in 2011 and finished her residency in Family Medicine, and she is proud to say she is a Metis physician born and raised in Winnipeg, Manitoba, Canada. Dr. Anderson's passion for Cannabinoid medicine started in 2017, when her son with intractable epilepsy had failed all treatments and she was forced to close her practice. Seizing multiple times per hour she knew the outlook was dire, and after one dose of CBD she saw dramatic results. Since then, Dr. Anderson has committed herself to helping other children who have failed all options explore cannabinoids, and she has seen amazing results.

Dr. Hemant Kumar Bid is a top educator in the field of Biotechnology and Medical Cannabis, where he uses his extensive background in biotechnology research and cannabinoid research to educate cannabis and biotechnology professionals and infuse the industry with science-backed legitimacy. In addition to serving as a Program Director for the Morehouse School of Medicine and teaching graduate students, Hemant also serves as a Scientific Advisor for Essentia Scientific, a company that delivers an array of cannabinoid product solutions, including acidic cannabinoids, with their patented water-as-solvent extraction technology. During our conversation, we discuss:  What are cannabinoid acids and how do they differ from the neutral cannabinoids  Why have cannabinoid acids been traditionally overlooked in research and consumer products  How THCA produces different effects than THC  Why CBDA is more bioavailable and more potent than CBD  How new extraction and stabilization techniques are helping make cannabinoids acids more accessible  and more  Thanks to This Episode's Sponsor: CANN Since 2015, CANN has been building a strong network of scientists in the cannabis space to promote scientific innovation, safety, and development through education, research, and the empowerment of the scientific community. To learn more about what CANN has to offer please visit their website at www.cann-acs.org. Additional Resources Essentia Scientific Website Email Hemant - Hibid@msm.edu Submit Your Abstract for CannMed 26 Meet the CannMed 26 Advisory Board

In this mind-expanding episode, Darin sits down with Dani Fontaine — researcher, practitioner, and expert on the human body's forgotten communication system: the endocannabinoid system. They unravel how this network regulates everything from mood and sleep to pain and consciousness — and why it was deliberately scrubbed from mainstream medical education. Dani reveals how cannabinoids, light, sound, and nature all communicate with our body's receptor fields — shaping the way we feel, heal, and perceive the world. Together they explore the profound spiritual and scientific implications of this hidden system, and how it connects us back to balance, nature, and truth.     What You'll Learn 00:00:00 - Welcome to the SuperLife Podcast 00:00:32 - Sponsor: Energy Bits 00:01:52 - Introducing Guest Danny Fontaine: Cannabis Pioneer and Plant Medicine Healer 00:04:54 - Deep Dive: What is the Endocannabinoid System (ECS)? 00:06:30 - ECS: The Homeostasis and Retrograde Signaling System 00:09:20 - ECS as a Receptive System for Subtle Energies and Environment 00:10:23 - Endocannabinoid System Toning (X-Tone) 00:12:58 - When the ECS Gets Worn and Depleted 00:16:34 - ECS Receptors on Every Cell, Fascia, and Neural Makeup 00:19:14 - How the ECS Breaks Down: The Impact of False Light 00:22:11 - The ECS and Non-Photon Rich Food 00:23:40 - Modulating the ECS Through the Six Senses (Touch and Breath) 00:24:38 - Mitochondria and ECS Receptors (MTK, CB1) 00:25:14 - Endogenous ECS and the Need for Proper Nutrients 00:27:11 - Cannabis as our Phyto Twin: The Plant Factor 00:27:57 - THC and the Suppression of Anandamide (Bliss Molecule) 00:31:44 - Sponsor: Fatty 15 00:35:25 - The Vast Amount of ECS Research & Medical Suppression 00:38:27 - Cannabinoids, Pain, and Individual Assessment 00:40:29 - Modulating ECS with Nature: Terpenes like Pinene 00:42:51 - Olfactory System as the Most Sophisticated Input 00:47:03 - ECS as the "Microscope Moment" for Health 00:48:23 - Pinene, CB1, and TRP Receptors in Pain Management 00:50:39 - The ECS, Collagen, and Hyaluronic Acid Fluctuation 00:51:44 - Working with the ECS for Faster Results (Cancer and Genetic Mutations) 00:55:06 - Sponsor: SuperLife Patreon 00:56:39 - Measuring the ECS with Bio-Field Technology 00:57:29 - The Danger of THC Stacking and Immunosuppression 00:59:30 - Overwhelmed Cells and Fake Inputs 01:00:12 - Hemp as a Homeostasis Plant for the Planet (Soil Remediation/Carbon) 01:02:06 - ECS Strength in Animals vs. Humans 01:04:08 - Why Cannabis and Hemp Were Suppressed 01:07:07 - The Historical Use of Cannabis in Medicine 01:08:12 - Hemp's Nutritional Profile (Amino Acids and Omegas) 01:09:37 - Ayahuasca, Receptor Overexpression, and Looping 01:13:33 - Importance of ECS Knowledge and Application 01:14:58 - Exercise, Anandamide, and ECS Toning 01:15:22 - Cold Plunge and Shocking the ECS and Hormones 01:17:16 - Takeaways: Light, Movement, Sound, and Breath 01:21:41 - ECS: The Main Signaling and Communication System 01:23:28 - Final Thoughts: ECS as the Conduit to Self and Spirit     Thank You to Our Sponsors: Fatty15: Get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/DARIN and using code DARIN at checkout. EnergyBits: Get 20% off your entire order by going to https://energybits.com/ and using code DARIN at checkout.     Find More from Dani Fontaine Instagram: @danifontaine Website: danifontaine.com Products: Try Dani's Nature Root     Connect with Darin Olien: Website: darinolien.com Instagram: @darinolien Book: Fatal Conveniences Platform & Products: superlife.com     Key Takeaway “Your endocannabinoid system isn't just a biology lesson — it's a bridge between your body and the universe. When you feed it light, breath, and truth, you remember what balance actually feels like.”

Caitlyn Krebs is a biotech executive with over 20 years of experience advancing therapeutics, diagnostics, and digital health innovations. She is the Co-Founder and CEO of Nalu Bio, where she leads the development of next-generation cannabinoid-inspired therapeutics with pharmaceutical-grade quality and scalability. Over her career, Caitlyn has completed more than 50 strategic partnerships and product launches across biopharma, diagnostics, and digital health. Nalu Bio recently announced positive results for a cannabinoid-based therapeutic for endometriosis, a condition that affects 200 million women worldwide. During our conversation, we discussed: Understanding Endometriosis - symptoms, diagnosis, and current treatment options How Millions of women with endometriosis are using CBD or THC to self-treat symptoms What makes the endocannabinoid system a prime target for for endometriosis How Nalu Bio uses an AI platform to accelerate the development of novel, consistent, and non-addictive cannabinoid molecules The potential for broader applications for cannabinoid-based therapeutics, similar to GLP-1 therapies The timeline for future clinical trials and potential FDA-approval Thanks to This Episode's Sponsor: The Society of Cannabis Clinicians The Society of Cannabis Clinicians' Med Cann conference offers a rare opportunity for clinicians to dive deep into the clinical realities and therapeutic potential of medical cannabis and psychedelics. Designed with healthcare providers in mind, their sessions focus on case-based learning, emerging protocols, and real-world challenges—offering practical insights that can be immediately applied in your practice. Learn more at cannabisclinicians.org and use code "CP15" to receive 15% Off Your Registration Additional Resources NaluBio.com Big Data Begins to Crack the Case of Endometriosis (UCSF) CannMed Call for Abstracts

Dr. Hoffman continues his conversation with Dr. Rob Verkerk, Founder, Executive & Scientific Director, Alliance for Natural Health International & Alliance for Natural Health USA.

Dr. Robert Verkerk, the Executive Director of the Alliance for Natural Health (ANH), discusses a wide range of topics, including the intersection of high-tech medical advances and natural therapies. Dr. Verkerk explains the mission of ANH, emphasizing the defense of health freedom and the promotion of natural approaches to health. They delve into various initiatives that ANH is working on, such as defending access to natural thyroid, reversing bans on important supplements like NMN and NAC, and challenging FDA regulations that restrict information on the benefits of natural products. The episode also highlights the importance of maintaining a balanced approach to healthcare and the ongoing efforts to reform regulatory frameworks that favor pharmaceutical interventions over natural alternatives.

In this week's episode of High on Home Grown, we dive into the latest cannabis headlines from around the world: Macky breaks down a fascinating study showing how soil quality directly impacts cannabinoid and terpene levels in cannabis plants (leafie). He also covers a new report warning that regular cannabis use may pose risks for those over 65 (Stanford Report). Margaret shares a troubling story from Wales, where residents complained about the persistent smell of cannabis at Parc Prison, revealed during an inquest (ITV News). Billy highlights how a popular UK design show is giving hempcrete a major global spotlight, pushing this sustainable material into the mainstream. John reports on a new poll showing that most Americans see cannabis as a healthier option than alcohol, and many believe nationwide legalisation could happen within five years. Join us for another packed episode full of science, politics, and cannabis culture.

Dr. Centor discusses currently available evidence about high-concentration cannabis products and mental health outcomes with Drs. Paula Riggs and Jonathan Samet.

Synthetic progestogens hike risk for brain tumors, natural progesterone safe; Healthy microbiome, good genes, clean lifestyle propel world's oldest woman to age 117; Can you take too much selenium? Cannabis extract scores vs. low back pain; Can vitamin K prevent breast calcifications? Are we making progress vs. pancreatic cancer? 

The cause of autism revealed—is it Tylenol? Is there an ideal probiotic for Crohn's Disease? Treating constipation by modifying the microbiome with botanicals; ACTION ALERT: If Congress has its way, 95% of natural hemp products with CBD/THC may be banned by year's end! The popular diet that reverses psoriasis; A daily habit that could save you from chronic back pain.

We love to hear from our listeners. Send us a message. On this week's episode, Joel Latham, President and CEO at Incannex Healthcare, talks about developing cannabinoid and psychedelic combination therapies for conditions as diverse as sleep apnea, rheumatoid arthritis, and generalized anxiety disorder. Joel walks through his funding strategy for the publicly-traded company, his desire to lead in a new category of medicine, and what comes next. Access this and hundreds of episodes of the Business of Biotech videocast under the Business of Biotech tab at lifescienceleader.com. Subscribe to our monthly Business of Biotech newsletter. Get in touch with guest and topic suggestions: ben.comer@lifescienceleader.comFind Ben Comer on LinkedIn: https://www.linkedin.com/in/bencomer/

RealDGC.com

Did you know that people can use cannabis as an effective psychedelic without the same health concerns as mushrooms or ayahuasca?Educator and Coach Ryan Sprague explains the benefits of cannabis as a psychedelic and a tool for growth but only if you understand how to use it this week on Spirit Gym.Learn more about Ryan and his work on his Highly Optimized website and on social media via Instagram here and here and YouTube. Listen to Ryan's Highly Optimized podcast on Apple Podcasts or wherever you listen to them.For Spirit Gym listeners: Register for Ryan's free workshop — The Untapped Power of Cannabis Coaching: Harness the Only Legal Psychedelic to Unlock Your Clients' Full Potential & Transform Their Lives — on Sept. 12 at noon EDT at this link.Also, check out Ryan's courses, including Breathe With Cannabis, at this link and save 10% on any of them by using the CHEK10 promo code at checkout. Join the BWC Collective, experience monthly ceremonies and access all past replays for $33 at this link (exclusively for Spirit Gym listeners). (Special offers from Spirit Gym guests are time-sensitive and at their discretion to redeem after 30 days.)Timestamps4:15 Cannabis as a psychedelic.12:03 The “trip” that changed Ryan's life forever.16:35 The edibles industry's dirty secrets may harm you.25:36 A Thai stick strain.33:44 Looking for cannabis strains that contain less than 20 percent THC is really hard.41:56 Cannabis can't be a personal growth tool unless you understand how to use it.53:19 The Goldilocks Zone.59:06 Is using mushrooms and cannabis together a good idea?Find more resources for this episode on our website.Music Credit: Meet Your Heroes by Brave as BearsAll Rights Reserved MusicFit Records 2024Thanks to our awesome sponsors:PaleovalleyBIOptimizers US and BIOptimizers UK PAUL15Organifi CHEK20Wild PasturesKorrect SPIRITGYMPique LifeCHEK Institute/CHEK AcademyZen in the Garden We may earn commissions from qualifying purchases using affiliate links.

In this episode of Quah (Q & A), Sal, Adam & Justin coach four Pump Heads via Zoom. Mind Pump Fit Tip: 10 Signs You May Benefit from Hormone Therapy. (2:26) Justin's NASCAR experience. (27:41) To share or not to share. (36:51) Incredible brain studies using Brain.fm. (41:52) This is not financial advice. (48:00) Cannabinoids and heart health. (51:13) #ListenerLive question #1 – How can I heal my relationship with food? (57:27) #ListenerLive question #2 – Is there any difference in strength results between a conventional back squat compared to using the safety squat bar? (1:12:42) #ListenerLive question #3 – What are the signs your calories are too low? (1:16:39) #ListenerLive question #4 – What program should I run after going through the RGB bundle? (1:30:09) Related Links/Products Mentioned Ask a question to Mind Pump, live! Email: live@mindpumpmedia.com Visit Brain.fm for an exclusive offer for Mind Pump listeners. ** Get 30 days of free access to science-backed music. ** Visit NED for an exclusive offer for Mind Pump listeners! ** Code MINDPUMP at checkout for 20% off ** July Special: MAPS Split or Anabolic Metabolism Bundle 50% off! ** Code JULY50 at checkout ** Mind Pump #2502: Hormone Therapy for Aesthetics With Dr. Lauren Fitzgerald Mind Pump #2447: The Keys to Visceral Fat Loss & Muscle Gain With Dr. Tyna Moore Low Testosterone and Brain Fog: Understanding the Link  Algorithmic Music - brain.fm Science - Brain.fm Knowledge Base Study: Cannabigerol (CBG) Reduces Fat Accumulation and Improves Heart Cell Function Under Lipid Overload Visit Pre-Alcohol by ZBiotics for an exclusive offer for Mind Pump listeners! ** Promo code MINDPUMP25 for 15% off first-time purchasers on either one-time purchases, (3, 6, 12-packs) or subscriptions (6, 12-pack) ** Mind Pump #2210: Best Workouts for Bulking & Cutting Mind Pump #2312: Five Steps to Bounce Back From Overtraining 7-Day Overtraining Rescue Guide | Free by Mind Pump Media Mind Pump Podcast – YouTube Mind Pump Free Resources People Mentioned LAUREN FITZ, M.D. (@drlaurenfitz) Instagram