Podcasts about osu college

Welcome to Chapter 65! My guest today is James Cooper. James is the Oklahoma City Councilman for Ward 2 and an Artist in Residence for the English department at OCU, where he teaches courses on writing and horror. His work has been published in the Oklahoma Gazette and the Huffington Post and he was named a Champion of Pride by Advocate Magazine and received the Rising Star Award from the OSU College of Arts and Sciences.We're talking about James' debut novel - Moonlit Massacre - a horror novel about a mass murder following in the vein of the infamous Sirloin Stockade murders in Oklahoma City in the 70s. Over the course of the conversation we also talk about Care Bears, Nightmare on Elm Street, Lil Wayne, jazz, a little OKC politics, and a particular influence that you'll have to hear to believe. As you can imagine, the conversation turns to violence a bit, so be advised as you decide to listen. Connect with James: website | Instagram | FacebookShop the Bookcast on Bookshop.orgMentioned on the Show:Lou BerneyStephen Graham JonesMen, Women, and Chainsaws - Carol CloverA Single Man - Christopher IsherwoodNo Country for Old Men - Cormac McCarthyBlood Meridian - Cormac McCarthyOKC: Second Time Around - Steve LackmeyerFunny Money - Mark SingerReconstructing the Dreamland - Alfred L. BrophyInvisible Man - Ralph EllisonMoffie - Andre Carl Van Der MerweConnect with J: website | TikTok | Twitter | Instagram | FacebookShop the Bookcast on Bookshop.orgMusic by JuliusH

Ravis and Coach discuss this weekend's college and pro football schedule plus the guys make their T&W Tire Locks of the Week! Follow Matt on X @mattravis and WWLS @sportsanimal, thesportsanimal.com, and The Sports Animal app!See omnystudio.com/listener for privacy information.

Ravis and Coach preview the weekend of college and pro football, including road games for the Cowboys and Sooners! Follow Matt on X @mattravis and WWLS @sportsanimal, thesportsanimal.com, and The Sports Animal app!See omnystudio.com/listener for privacy information.

Ravis and Coach discuss what's next for the Sooners and Cowboys, plus the upcoming week in college football and their top 5 teams in the NFL! Follow Matt on X @mattravis and WWLS @sportsanimal, thesportsanimal.com, and The Sports Animal app!See omnystudio.com/listener for privacy information.

Ravis discusses wins for the Sooners and Cowboys as well as the rest of the weekend in college and pro football! Follow Matt on X @mattravis and WWLS @sportsanimal, thesportsanimal.com, and The Sports Animal app!See omnystudio.com/listener for privacy information.

Ravis and Coach recap the weekend of college and pro football, highlighting wins for OU and OSU, plus their top five Big 12 teams and their Best Dozen nationally! Follow Matt on X @mattravis and WWLS @sportsanimal, thesportsanimal.com, and The Sports Animal app!See omnystudio.com/listener for privacy information.

The guys recap last weekend for the Sooners, Cowboys, college, and pro football, and they look ahead to a huge weekend with OSU hosting Utah and OU hosting Tennessee! Follow Matt on X @mattravis and WWLS @sportsanimal, thesportsanimal.com, and The Sports Animal app!See omnystudio.com/listener for privacy information.

Ravis discusses nerve wracking wins for the Sooners and Cowboys, plus the rest of the weekend in college football and the NFL! Follow Matt on X @mattravis and WWLS @sportsanimal, thesportsanimal.com, and The Sports Animal app!See omnystudio.com/listener for privacy information.

Ravis and Coach discuss the weekend of football, and Pat does not hold back on Tyreek Hill or Oklahoma State! Follow Matt on X @mattravis and WWLS @sportsanimal, thesportsanimal.com, and The Sports Animal app!See omnystudio.com/listener for privacy information.

The guys discuss the biggest issues facing the Sooners and Cowboys moving forward plus the rest of the college and pro football this weekend! Follow Matt on X @mattravis and WWLS @sportsanimal, thesportsanimal.com, and The Sports Animal app!See omnystudio.com/listener for privacy information.

Ravis discusses what he wants to see from the Sooners and Cowboys in week two, plus Florida State falling to 0-2 and the Eagles/Packers game in Brazil! Follow Matt on X @mattravis and WWLS @sportsanimal, thesportsanimal.com, and The Sports Animal app!See omnystudio.com/listener for privacy information.

Ravis and Coach discuss the Sooners and Cowboys, plus Coach talks about Leslie O'Neal going into the OSU Ring of Honor, and the guys give their Best Dozen in college football for the week! Follow Matt on X @mattravis and WWLS @sportsanimal, thesportsanimal.com, and The Sports Animal app!See omnystudio.com/listener for privacy information.

The guys discuss OU, OSU, and college football, plus what's going on in Tallahassee and an interesting weekend of high school football! Follow Matt on X @mattravis and WWLS @sportsanimal, thesportsanimal.com, and The Sports Animal app!See omnystudio.com/listener for privacy information.

The guys discuss the weekend of college football and look ahead to the first week of NFL action! Follow Matt on X @mattravis and WWLS @sportsanimal, thesportsanimal.com, and The Sports Animal app!See omnystudio.com/listener for privacy information.

OSU College of Forestry, analyzed data from thousands of reforestation sites across 130 countries. The results show that roughly half the time it's better to let nature take its course.

This week, we return to our series at the OSU College of Veterinary Medicine for a discussion with Dr. Meredyth Jones about lameness in beef cattle. Many producers are comfortable treating what they assume is foot rot, however there are many different issues that cause lameness that are not foot rot. Many of these other [ Read More ]

Join the Sanders sisters and "OSHA Lady" Karen Daw as they dive deep on all things patient safety, honoring Patient Safety Awareness Week in March. Featuring Karen Daw Karen's Instagram Karen's Website Karen's Facebook Page About Karen: Karen Daw is an award-winning national speaker, author, and Authorized OSHA Trainer. She earned her BA from the Ohio State University and her MBA with concentrations in Healthcare Administration and Business Management. Karen was recruited from the Emergency Department to the OSU College of Dentistry as the Safety Director. The federal government, OSAP and dental manufacturers have benefited from Karen's expertise. She now coaches practices across the country live and via Zoom with a “This is going to be so much fun!” approach to OSHA compliance. Interesting fact - Karen recently earned her certificates in the following: Clinical Hypnotherapy, Time Techniques, EFT, Reiki, FIRES Technique, Neurolinguistic Programming (NLP) and Life and Success Coaching through a trauma-sensitive/informed lens. Something people don't know about me – I am a sucker for underdogs, the voiceless, and have a (MASSIVE and inordinate) sense for justice and fairness

OSU Men's Basketball Coach Chris Holtmann was fired after going just 30-30 since the start of last season, Notre Dame is over ranked in at least one way too early top 25 college football list, Tyrese Haliburton speaks more on the NBA's 65-game rule and why the players were let down by their players association, Dusty May is the perfect candidate for OSU, college football win totals for IU, Purdue, OSU and Michigan are set for the upcoming season and over/under on what we expect, the Oakland A's could be crawling back to Oakland for the next few years, and a man was fined and sentenced to probation for bringing snakes in his pants across the U.S.-Canada border. See omnystudio.com/listener for privacy information.

We spend a lot of time talking about the grief we experience as pet guardians whose companion animals have grown old or become terminally ill. There are other types of loss and grief, though, that pet guardians can experience. Many carry with them elevated levels of trauma -- sudden death, runaways, theft, loss of custody due to the end of a relationship -- and I would love to interview someone on those very subjects. Today, though, we're talking about behavioral issues in our companion animals, especially dogs, and the way we manage and treat reactivity or aggression. Dr. Kyle Bohland of the Ohio State University Veterinary Medical Center joins me to talk about his work in behavioral studies and the intricacies around behavioral euthanasia. Dr. Bohland was born and raised in Fremont, Ohio, and completed his undergraduate degree in economics at the University of Akron. After graduation, he earned his master's in science in agricultural, environmental and development economics from Ohio State University. Along the way, he realized veterinary medicine was his true calling, a career he'd dreamed of since childhood. He graduated from the OSU College of Veterinary Medicine in 2018 and worked in general practice doing preventive medicine, general medicine, urgent care, surgery and dentistry. All the while, he was working on his residency program in behavioral medicine at OSU and then joined the faculty full time. His topics of interest lie in end of life care, pain management and the behavior of shelter-housed animals. He lives in Columbus, Ohio, with his wife, 6-year-old child, four senior dogs, one cat and a few fish. What to listen for 2:42 Early socialization and its impact on dog behavior 8:29 The positive and negative impacts COVID-19 has had on dog behavior 13:27 Trauma and reactivity in shelter dogs 21:55 How the unregulated dog training industry affects dog behavior --- Send in a voice message: https://podcasters.spotify.com/pod/show/onelastnetwork/message Support this podcast: https://podcasters.spotify.com/pod/show/onelastnetwork/support

Ravis and Coach discuss a new defensive coordinator at OU, Alan Bowman coming back to OSU, college football news, and week 18 in the NFL! Follow the Sports Animal on Facebook, Instagram and X PLUS Sports Morning on X Listen to past episodes HERE! Follow the Sports Morning podcast on Apple Google and SpotifySee omnystudio.com/listener for privacy information.

This episode features a fireside chat with ACS President E. Christopher Ellison, MD, FACS, about his career and life lessons. Dr. Ellison is the Robert M. Zollinger Professor of Surgery Emeritus at The Ohio State University College of Medicine in Columbus. He previously served as chair of the Department of Surgery, interim dean at the OSU College of Medicine, and president and CEO of the OSU Physicians Practice Plan.   The program host is Mohsen Shabahang, MD, PhD, FACS, for the ACS Academy of Master Surgeon Educators.   Talk about the podcast on social media using the hashtag #HouseofSurgery.

William W. Long, M.D., F.A.A.P – Received his education at West Virginia University in Morgantown, West Virginia. He completed his internship and residency at Columbus Children's Hospital, where he also served as Chief Resident. Dr. Long is a Clinical Assistant Professor of Pediatrics at The Ohio State University. Dr. Long is board certified in Pediatrics and a Fellow of the American Academy of Pediatrics. Dr. Long is actively involved with Nationwide Children's Hospital, serving as Medical Staff president in 2004. He also teaches at the hospital and OSU College of Medicine.President of CPP (Children's Practicing Pediatricians) is an independent nonprofit medical association established in 1985 by pediatricians on Nationwide Children's Hospital in Columbus, Ohio medical staff. With over 35 years of operating experience, CPP has become a preeminent primary care “chamber of commerce,” offering services and advocating on behalf of primary care physicians.Support the show

Psychedelics researcher Meghan DellaCrosse breaks down her research on psilocybin, the results from a new study looking at magic mushrooms use for bipolar disorder, the benefits and drawbacks of using psilocybin, and the future of psychedelics research for mental health. Hosted by Dr. Emma Morton. Meghan DellaCrosse is a doctoral candidate in clinical psychology at the Wright Institute in Berkeley, CA. Following completion of pre-doctoral internship at Wexner Medical Center's Early Psychosis Intervention Center at the Ohio State University (OSU) in June 2023, Meghan will begin a post-doctoral fellowship at the Center for Psychedelic Drug Research and Education at the OSU College of Social Work. She has contributed to research and manuscript development as a part of the Translational Psychedelic Research (TrPR) Program at UCSF where she also worked as a clinical assessor on various studies including investigations of social deficits in Veterans with schizophrenia, and psilocybin as a novel treatment for depression and Parkinson's disease. Meghan is passionate about interdisciplinary research and holds master's degrees in clinical psychology from Columbia University, Teachers College (NY), and art history from CUNY Hunter College (NY). As a somatic educator and qualified Mindfulness-Based Stress Reduction instructor, Meghan's research interests focus on novel treatments and the integration of the body into mental health care to support people with serious mental illness, as well as promoting mental health literacy and reducing stigma. More on this episode: https://talkBD.live/psilocybin-research #talkBD⁠⁠ gathers researchers, people with lived experience, healthcare providers, and top bipolar disorder experts from around the world to discuss and answer the most important questions about living with bipolar disorder. Learn more about the talkBD Bipolar Disorder Podcast and upcoming episodes at ⁠⁠https://talkBD.live

Graduate student Rachel Zitomer and Dr. Jim Rivers, an animal ecologist in the OSU College of Forestry about their research on the impacts of land management practices on wild bees outside of agricultural systems.

This week, Dana sits down with Dr. Meredyth Jones, Associate Professor at the OSU College of Veterinary Medicine to discuss a survey that she did with Rural Oklahoma Veterinarians. Through the survey, Dr. Jones asked for perspective on what makes the livestock producer-veterinarian relationship successful. Veterinary Viewpoints: Cultivating veterinarian and producer relationships – article by [ Read More ]

On April 2, 2021, the OSU/A&M Board of Regents selected Dr. Kayse Shrum as the 19th president of Oklahoma State University. A native Oklahoman, President Shrum earned her doctor of osteopathic medicine degree from the OSU College of Osteopathic Medicine and has completed executive leadership and management training programs at Harvard University and Stanford University. Since taking office in July 2021, Dr. Shrum has forged a new chapter for OSU — boldly facing challenges like conference realignment and COVID-19 while positioning the university for future success by embarking on a strategic planning process. The systemwide strategy process will guide the future of OSU and secure its position as the nation's premier land-grant university — with a focus on creating and discovering solutions to societal problems, providing students with a world-class education and sending them into the world after graduation well-equipped to handle the challenges before them.  If you want to see if it's a good fit to work with Jen V. and JRT on speaking courageously as a leader, let's chat: https://www.voicefirstworld.com/chat  

The guys discuss OSU hoops, conference tournament action, and Oklahoma high school state tournaments!See omnystudio.com/listener for privacy information.

The guys discuss OSU exiting the Big 12 Tournament as well as all the other college and pro hoops!See omnystudio.com/listener for privacy information.

Craig recaps all of the college and pro hoop from Thursday, including a rough exit from the Big 12 Tournament for OSU.See omnystudio.com/listener for privacy information.

It was Friday April 1, 2006, the last day of classes before Spring Break for students at the Ohio State University in Columbus, OH. 27 year old Brian Shaffer, a second year medical school student, had plans of going out for a few drinks with is friend William “Clint” Florence to kick off the weekend, before taking off for Miami Fl with his girlfriend Alexis Waggoner. They had planned a spring break vacation trip given to Brian by his mother, Renee Shaffer. Some close to the couple thought that Brian might even propose to Alexis while in Miami. The two were to board their flight that Monday morning, but Brian would never make it to the airport for his flight.Brian Shaffer was born on February 25, 1979 to Renee and Randy Shaffer. Brian also has a younger brother named Derek. Brian grew up in Pickerington, OH a superb just out side Columbus, OH. He graduated High School in 1997, and then enrolled at Ohio State University. Brian was on the “6 year plan” and in 2003 earned is bachelors degree in Microbiology. Brian then enrolled in the OSU College of Medicine in 2004. He was in his second year of medical school at the time of his disappearance. While in medical school, Brian met his future girlfriend, Alexis Waggoner from Toledo, OH. Brian was always attracted to the “beach life”. He even once stated that “the medical thing is a temporary gig” and that his real passion was to start his own back playing music in the style and Jimmy Buffet. Could Brian have been foreshadowing his own future ?Brian was very close to his parents, especially his mother, Renee. Unfortunately, she was diagnosed with cancer and would pass away in 2006, just three weeks before Brian would disappear. The loss of his mother was especially tough for Brian, although those around him said he handled it well. Although, Brian disappeared in 2006, the Shaffer family would suffer another deviation loss in 2008. Brians father Randy would be killed by a falling tree branch just outside his home, while he was out surveying damage caused by strong winds in the area from the remnants of Hurricane Ike which had made their way all the way up to the Ohio Valley. This had left only Derek, Brian's younger brother to grieve alone, as he has lost his mother, his brother, and his father in a span of only two years.

Today on the show it is an honor to have the President of the American Optometric Association on, Dr. Bob Layman. We talk about advocating for the role of optometrists, how the AOA is helping advocate for the profession, and how we can each individually break down barriers in the profession as optometrists.  About Our Guest:  Robert C. Layman, O.D., was elected to the American Optometric Association Board of Trustees at the 116th Annual AOA Congress & 43rd Annual AOSA Conference: Optometry's Meeting® in June 2013 and serves as President of the Board of Trustees. In addition to his position as President, Dr. Layman serves as chair of the Executive Committee and the Personnel Committee and is the Speaker of the House of Delegates. Additionally, Dr. Layman is a member of the Center for Independent Practice Committee. He is the liaison trustee to the Council on Research Committee and the National Board of Examiners in Optometry group.  He also serves as the liaison trustee of affiliate associations in Alaska, Arizona, Florida, Montana, New Mexico, and Utah. Prior to his election to the AOA Board of Trustees, Dr. Layman's 30-plus years of consecutive AOA volunteer service include the following chairmanships: Diabetes Project Team, Optometric Executive's Project Team, Information and Member Services Group Executive Committee Chair, Non-Dues Income Committee, Assistance to Graduates Project Team and 401(K) Committee Chair. Dr. Layman was honored with the AOA Optometrist of the Year award in 2006. He has also received the Ohio Optometrist of the Year, Ohio Young Optometrist of the Year, Ohio Key Optometrist of the Year and Outstanding Senior Student Awards. Dr. Layman is a past president of the Ohio Optometric Association (OOA). He served as the OOA Electronic Health Records Task Force liaison to the Northwest Ohio Regional Extension Center/Health Information Partnership from 2010-2014. Dr. Layman chaired the EastWest Eye Conference from 2009-2011. He has presented the RealEyes Classroom Initiative curriculum in his community since the program's inception in 2001. Dr. Layman is a graduate of The Ohio State University (OSU) College of Optometry, where he was named one of OSU College of Optometry's Top 100 Notable Alumni during the 100th anniversary of the college. He has served as a vision consultant to the University of Toledo Athletic Department for more than 25 years. He has been an adult leader in Boy Scout Troop 87, a volunteer with the Mildred Bayer Homeless Clinic of Toledo, and a member of the YMCA Board of Managers. Dr. Layman is an owner of Pinnacle Eye Group in Lambertville, Michigan and Great Lakes Vision Care in Monroe, Michigan, and lives with his wife, Barb, in Toledo, Ohio. They have four grown children. He is energized to continue advancing the profession by working closely with affiliates, increasing membership, and securing the proper place for optometry in health care reform. Total Patient Care Workshops: The Total Patient Care On-Demand Workshop The Mastermind 6 Month Total Patient Care Program (enrolling now for spring 2023)  ---------------------------------------------------------- For our listeners, use the code 'EYECODEMEDIA22' for 10% off at check out for our Premiere Billing & Coding bundle or our EyeCode Billing & Coding course. Sharpen your billing and coding skills today and leave no money on the table!  Show Sponsors: CooperVision MacuHealth EssilorLuxottica  

Oregon State University research shows that the drier air may have a greater effect on Douglas fir trees than lack of rain. Karla Jarecke, a postdoctoral researcher in the OSU College of Earth, Ocean, and Atmospheric Sciences, led the research and talks about the findings.

Craig recaps Bedlam, college football, and the NFL action from over the weekend!See omnystudio.com/listener for privacy information.

Craig and Coach break down OU's win over OSU and all of the college and pro football from over the weekend!See omnystudio.com/listener for privacy information.

The guys recap the Sooners' win over the Cowboys and all of the college and pro football from this weekend!See omnystudio.com/listener for privacy information.

Craig and Coach discuss rough days for OSU and OU plus all of the college football and NFL from over the weekend!See omnystudio.com/listener for privacy information.

Craig discusses the Sooners' and Cowboys' losses plus all of the college and pro football from this weekend!See omnystudio.com/listener for privacy information.

Craig and Mark dive into what went wrong for the Sooners and the Cowboys on Saturday, plus the guys recap all of the other college and pro football from over the weekend!See omnystudio.com/listener for privacy information.

We got the opportunity to sit down and talk with Judge Keith McGrath at the roundtable. Here's what you need to know about him. Judicial ExperienceJudge, Tenth District Court of Appeals, Appointed by Governor DeWine in April, 2022  Education1992 Juris Doctor, The Ohio State University Moritz College of Law, Columbus, Ohio 1989 Bachelor of Arts, Marshall University, Huntington, West Virginia 1984-1987 United States Coast Guard Academy, New London, Connecticut  Bar MembershipsAdmitted to Ohio Bar, November 1992 Admitted to Federal Bar for the Southern District of Ohio, January 1993 Admitted to The Supreme Court of the United States of America, May 2000  Previous Non-Judicial Work Experience1997-1998, 2002-2022 Franklin County Prosecutor's Office - Senior Assistant County Prosecutor Senior Trial Staff, Floor Leader, Member of Vehicular Crimes Unit Special Prosecutor for Clark, Montgomery and Muskingum Counties 2012, 2018, 2021 1998-2002 Contract Attorney, Washington D.C. 1993-1997 Columbus City Attorney's Office, Prosecutor's Division, Assistant City Prosecutor  Military Service1984-1987 United States Coast Guard Honorable Discharge April 10, 1987 Received honors for Unit Commendation Medal for extremely meritorious service in support of Coast Guard operations  Professional and Community ActivitiesMentor: The Supreme Court of Ohio Lawyer to Lawyer Mentoring Program 2022 Instructor: Law Enforcement classes in ARIDE and DICE 2012-2022 Member: Charity Newsies, Columbus, Ohio 1997-present Instructor: OPATA, Accident Reconstruction 2012-2018 Coach: Pee Wee Division, Whetstone Soccer League, Columbus, Ohio 2013-2014 Recipient: 2011 Award of Excellence presented by MADD (Mothers Against Drunk Driving) Judge: University of Maryland Regional Trial Competition 1999-2001 Instructor: The Columbus Bar Association Homeless Project, Columbus, Ohio 1995-1998 Instructor: The Ohio Center for Law Related Education, Columbus, Ohio 1994-1998 Instructor: Martin Essex School for the Gifted Mock Trial, Columbus, Ohio 1995-1998 Judge: Michael F. Colley Trial Competition, The OSU College of Law, Columbus, Ohio 1997 Judge: The OSU College of Law Herman Moot Court Competition, Columbus, Ohio 1993-1996 Submit your questions to http://www.lawyertalkpodcast.com/ (www.lawyertalkpodcast.com). Recorded at Channel 511, a production of 511 South High Media LLC. Stephen E. Palmer, Esq. has been practicing criminal defense almost exclusively since 1995. He has represented people in federal, state, and local courts in Ohio and elsewhere. Though he focuses on all areas of criminal defense, he particularly enjoys complex cases in state and federal courts. He has unique experience handling and assembling top defense teams of attorneys and experts in cases involving allegations of child abuse (false sexual allegations, false physical abuse allegations), complex scientific cases involving allegations of DUI and vehicular homicide cases with blood alcohol tests, and any other criminal cases that demand jury trial experience. Steve has unique experience handling numerous high publicity cases that have garnered national attention. For more information about Steve and his law firm, visit https://www.ohiolegaldefense.com/ (Yavitch & Palmer Co., L.P.A.)  You can also find Lawyer Talk on these platforms: Rumble: LawyerTalkPodcast Brighteon: LawyerTalkPodcast Gab: @LawyerTalkPodcast GETTR: @LawyerTalk Copyright 2022 Stephen E. Palmer - Attorney At Law

Gideon recaps the Sooners' win, the Cowboys' loss, and the rest of the college and pro football action from the weekend!See omnystudio.com/listener for privacy information.

Gideon and Coach break down the weekend of college and pro football, including OU's win in Ames and OSU's loss in Manhattan.See omnystudio.com/listener for privacy information.

Gideon and Mark discuss OU's win, OSU's loss, and the rest of the weekend in college football and the NFL!See omnystudio.com/listener for privacy information.

Craig and Coach discuss the Sooners and Cowboys as well as other big games this weekend in CFB and the NFL!See omnystudio.com/listener for privacy information.

Videos: Gary Null – Speaks to U.N. on Earth Day (Part 1 & 2) Iain McGilchrist, ‘We Need to Act' Iain McGilchrist is a former Fellow of All Souls College, Oxford, an associate Fellow of Green Templeton College, Oxford, a Fellow of the Royal College of Psychiatrists, a Fellow of the Royal Society of Arts, a Consultant Emeritus of the Bethlem and Maudsley Hospital, London, a former research Fellow in Neuroimaging at Johns Hopkins University Medical School, Baltimore, and a former Fellow of the Institute of Advanced Studies in Stellenbosch. He now lives on the Isle of Skye, off the coast of North West Scotland, where he continues to write, and lectures worldwide.   California's “holy herb” Yerba Santa found to be an effective natural treatment for Alzheimer's   Salk Institute for Biological Studies, September 19, 2022 Alzheimer's disease is the most common form of dementia, and aging is its primary risk factor. Therefore, researchers continue to look for ways to counter the effects of aging on the brain. In a recent study, researchers from The Salk Institute for Biological Studies discovered a potential natural treatment for Alzheimer's in the form of a medicinal herb found in California. In their study published in the journal Redox Biology, they found that yerba santa (Eriodictyon californicum), a plant native to California, contains an active compound called sterubin that could be used to treat people with Alzheimer's. Yerba santa, which is the Spanish for “holy herb,” is highly regarded as a medicine for respiratory diseases, bruising, fever, headaches, infections, and pain. For the current study, the researchers first examined 400 plant extracts with known medicinal properties for their ability to prevent oxytosis – a type of cell death that occurs in Alzheimer's disease – in mouse hippocampal nerve cells. The researchers found that sterubin exhibited the greatest protective effect against inflammation and other triggers of brain cell death. In particular, sterubin strongly reduced inflammation in microglia, which are brain cells that provide support to nerve cells. In addition, the researchers found that sterubin can remove iron from cells, helping to prevent iron accumulation. Iron accumulation can result in a type of nerve cell damage that accompanies aging and occurs in neurodegenerative problems. “Not only did sterubin turn out to be much more active than the other flavonoids in Yerba santa in our assays, it appears as good as, if not better than, other flavonoids we have studied,” said Pamela Maher, the corresponding author of the study. Vitamin B may reduce risk of stroke Zhengzhou University (China)  September 23, 2022   Researchers have uncovered evidence that suggests vitamin B supplements could help to reduce the risk of stroke, according to a study published in the journal Neurology. Vitamin B supplements are said to be beneficial for many health issues, including stress, anxiety, depression, dementia, Alzheimer's disease and heart disease. However, according to Xu Yuming of Zhengzhou University in Zhengzhou, China, previous studies have conflicting findings regarding the use of vitamin B supplements and stroke or heart attack. In order to determine the role of vitamin B supplements in the risk of stroke, Prof. Yuming and colleagues analyzed 14 randomized clinical trials involving a total of 54,913 participants  All studies compared use of vitamin B supplements with a placebo, or a very low dosage of the vitamin. All participants were then followed for a period of 6 months. Results of the analysis revealed that the participants taking the vitamin B supplements had a 7% reduced risk of stroke, compared with those taking the placebo supplements or a low dosage of vitamin B. The researchers found that a supplemental form of folate (vitamin B9) – a vitamin frequently found in fortified cereals – actually reduced the effect of vitamin B on the risk of stroke Additionally, the study showed that vitamin B12 did not have any effect on the risk of stroke.   Ginger may protect the brain from MSG toxicity, says fascinating research University of Jeddah (Saudi Arabia), September 23, 2013  For thousands of years, ginger has been hailed as a superfood for its healing properties that aid every system of the body. The oils that ginger contains are antibacterial, antiviral and antifungal, and ginger has even been found to inhibit cancer growth. Now a study has actually proven that ginger can reverse the damage done by monosodium glutamate, or MSG, a known harmful excitotoxin. After injecting pure MSG into rats for 30 days, researchers found subsequent withdrawal caused adverse effects including significant epinephrine, norepinephine, dopamine and serotonin depletion. Low levels of these important neurotransmitters can be detrimental to health. Subsequent to injecting lab rats with MSG, researchers injected ginger root extract for 30 more days and were able to completely reverse the neurotransmitter depletion and brain damage that MSG caused. Not only that, but the positive effects of ginger were maintained even after scientists stopped administering it! A wealth of independent studies show that MSG should be avoided at all costs. Also popularly printed on food labels as hydrolyzed protein, torula or autolyzed yeast, soy or yeast extract and soy protein isolate among some 40 other names, scientists have found that consuming MSG even in low doses can cause blood glutamate levels to fluctuate abnormally high and then stay there. Anyone suffering from a disease or immunity issue that would contribute to a weakened blood-brain barrier is then much more susceptible to the chemical seeping into his or her brain and doing damage. Studies have effectively linked MSG consumption to several neurodegenerative diseases, such as Parkinson's and Alzheimer's. Men with anxiety are more likely to die of cancer, study says Cambridge University's Institute of Public Health, September 20, 2022 Men over 40 who are plagued with generalized anxiety disorder are more than twice as likely to die of cancer than are men who do not have the mental affliction, new research finds. But for women who suffer from severe anxiety, the research found no increased risk of cancer death. That finding, presented at the European College of Neuropsychopharmacology's Congress in Vienna, emerges from the largest study ever to explore a link between anxiety and cancer. It tracked 15,938 Britons over 40 for 15 years. Even after researchers took account of factors that boost the risk of cancer, including age, alcohol consumption, smoking and chronic diseases, men with a diagnosis of generalized anxiety disorder were 2.15 times as likely to die of cancer than were those with no such diagnosis. Generalized anxiety disorder – a condition marked by excessive, uncontrollable worry about many areas of life – affected women more commonly than it did men. Among women in the large cohort studied, 2.4 percent suffered from the disorder. Among men in the cohort, 1.8 percent did. Whatever the relationship, says the study's lead author, the new findings identify extremely anxious men as a population whose mental and physical health should be closely tracked. “Society may need to consider anxiety as a warning signal for poor health,” said study lead author Olivia Remes of Cambridge University's Institute of Public Health. “With this study, we show that anxiety is more than just a personality trait,” but rather, a disorder linked to real and serious health risks. Out of Over 400 Compounds Analyzed, Red Grapes and Blueberries Are Tops In Boosting Immunity – So Effective They Work As Well As Drugs Linus Pauling Institute at Oregon State University, September 18, 2022Pterostilbene, an antioxidant produced by plants has been shown to exhibit exceptional properties in fighting infections, cancer, hypertriglycerides, as well as the ability to reverse cognitive decline. It is believed that the compound also has anti-diabetic properties. In an analysis of 446 compounds for their the ability to boost the innate immune system in humans, researchers in the Linus Pauling Institute at Oregon State University discovered just two that stood out from the crowd. Red grapes and blueberies both have an exceptional ability to significantly impact immune function. In fact, pterostilbene works as well as some commercial drugs.

Both of these compounds, which are called stilbenoids, worked in synergy with vitamin D and had a significant impact in raising the expression of the human cathelicidin antimicrobial peptide, or CAMP gene, that is involved in immune function.The research was published in Molecular Nutrition and Food Research, in studies supported by the National Institutes of Health.

Almost a decade ago, researchers discovered that pterostilbene helps regulate blood sugar and might help fight type-2 diabetes. The finding adds to a growing list of reasons to eat colorful fruit, especially blueberries, which are rich in compounds known as antioxidants. These molecules battle cell and DNA damage involved in cancer, heart disease, diabetes and perhaps also brain degeneration. 

Pterostilbene works as well as the commercial drug ciprofibrate to lower the levels of fats (lipids) and triglycerides — but they worked even more accurately. They are so specific that side-effects are non-existent.”Out of a study of hundreds of compounds, just these two popped right out,” said Adrian Gombart, an LPI principal investigator and associate professor in the OSU College of Science. “Their synergy with vitamin D to increase CAMP gene expression was significant and intriguing. It's a pretty interesting interaction.”This research is the first to show a clear synergy with vitamin D that increased CAMP expression by several times, scientists said.The CAMP gene itself is also the subject of much study, as it has been shown to play a key role in the “innate” immune system, or the body's first line of defense and ability to combat bacterial infection. The innate immune response is especially important as many antibiotics increasingly lose their effectiveness.

Grapes don't have to be fermented to contain this antioxidant. It's actually found in the skin of red grapes along with other nutrients, such as minerals manganese and potassium and vitamins K, C and B1.Stilbenoids are compounds produced by plants to fight infections, and in human biology appear to affect some of the signaling pathways that allow vitamin D to do its job, researchers said. It appears that combining these compounds with vitamin D has considerably more biological impact than any of them would separately. Fungus in humans identified for first time as key factor in Crohn's disease Case Western Reserve University, September 22, 2022 A Case Western Reserve University School of Medicine-led team of international researchers has for the first time identified a fungus as a key factor in the development of Crohn's disease. The researchers also linked a new bacterium to the previous bacteria associated with Crohn's. The groundbreaking findings, published in mBio, could lead to potential new treatments and ultimately, cures for the debilitating inflammatory bowel disease, which causes severe abdominal pain, diarrhea, weight loss, and fatigue. Mycology at Case Western Reserve and University Hospitals Cleveland Medical Center “Essentially, patients with Crohn's have abnormal immune responses to these bacteria, which inhabit the intestines of all people. While most researchers focus their investigations on these bacteria, few have examined the role of fungi, which are also present in everyone's intestines. Our study adds significant new information to understanding why some people develop Crohn's disease. Equally important, it can result in a new generation of treatments, including medications and probiotics, which hold the potential for making qualitative and quantitative differences in the lives of people suffering from Crohn's.” The researchers assessed the mycobiome and bacteriome of patients with Crohn's disease and their Crohn's-free first degree relatives in nine families in northern France and Belgium, and in Crohn's-free individuals from four families living in the same geographic area. Specifically, they analyzed fecal samples of 20 Crohn's and 28 Crohn's-free patients from nine families and of 21 Crohn's-free patients of four families. The researchers found strong fungal-bacterial interactions in those with Crohn's disease: two bacteria (Escherichia coli and Serratia marcescens) and one fungus (Candida tropicalis) moved in lock step. The presence of all three in the sick family members was significantly higher compared to their healthy relatives, suggesting that the bacteria and fungus interact in the intestines. Additionally, test-tube research by the Ghannoum-led team found that the three work together (with the E. coli cells fusing to the fungal cells and S. marcescens forming a bridge connecting the microbes) to produce a biofilm — a thin, slimy layer of microorganisms found in the body that adheres to, among other sites, a portion of the intestines — which can prompt inflammation that results in the symptoms of Crohn's disease. This is first time any fungus has been linked to Crohn's in humans; previously it was only found in mice with the disease. The study is also the first to include S. marcescens in the Crohn's-linked bacteriome. Additionally, the researchers found that the presence of beneficial bacteria was significantly lower in the Crohn's patients, corroborating previous research findings.

Last month, Oregon State University College of Forestry announced it had hired alumna Cristina Eisenberg as director of tribal initiatives. The new position aims to partner with tribes in Oregon and the region on restoration projects and recruiting Native American students. A forest ecologist by training, Eisenberg is also working with tribes in western Oregon on a new, three-year pilot project funded by the Bureau of Land Management to make forests more resilient to climate change by using Indigenous practices and environmental beliefs known as Traditional Ecological Knowledge.Eisenberg is also the forestry college's first associate dean of inclusive excellence, a role informed by her own experiences as a Latinx and Native American first-generation college student, to provide support and new opportunities for underrepresented students. Cristina Eisenberg joins us to discuss returning to Oregon State University to lead these new efforts within the College of Forestry.

Videos: Stunning AI shows how it would remove humans. w Elon Musk. Elon Musk's Last Warning 2022 – “I Tried To Warn You The Last Few Years” (BEFORE IT'S TOO LATE!!!) A terrifying prediction for 2030 (the Great Reset) Inflation Will Wipe Out 50% of Population, It's the End of America Warns Robert Kiyosaki Diets high in N-3 polyunsaturated fats may help decrease risk of breast cancer A new study evaluates associations between breast cancer risk and intake of n-3 polyunsaturated fatty acids, based on menopause status North American Menopause Society, July 27, 2022 Diet has long been reported to potentially affect breast cancer risk. Growing evidence suggests that n-3 polyunsaturated fatty acids (PUFAs) may play a role in the pathogenesis of breast cancer. A new study documents an inverse association between breast cancer risk and n-3 PUFA consumption, especially in premenopausal women who are obese.  Previous studies have been conducted to investigate the association of n-3 PUFAs with breast cancer risk but have shown mixed results. Many of these studies were performed only in postmenopausal women because the peak age for breast cancer is 60 to 70 years in western countries, whereas it is age 40 to 50 years in Asian countries. In this latest hospital-based, case-control study including nearly 1,600 cases, researchers not only examined the association between the intake of n-3 PUFAs in general with breast cancer, but they also looked at the effect of individual n-3 PUFAs. Good sources of n-3 PUFAs include fish, vegetable oil, nuts (especially walnuts), flax seeds and flaxseed oil, and leafy vegetables. Because the human body does not produce n-3 fatty acids naturally, these food sources are essential. The study concluded that a higher intake of marine n-3 PUFAs and total n-3 PUFAs was associated with a lower risk of breast cancer. Dietary a-linolenic acid, eicosapentaenoic acid, docosapentaenoic acid, and docosahexaenoic acid also were inversely associated with breast cancer risk. Such inverse associations were more evident in premenopausal women and women with certain types of breast tumors. In addition, a decreased risk of breast cancer was significantly associated with increasing n-3 PUFA intake in women who were overweight or obese but not in women of normal weight. There was a significant interaction between linoleic acid and marine n-3 PUFAs. Zinc can halt the growth of cancer cells, study reveals University of Texas Arlington,  July 22, 2022  Research out of the University of Texas at Arlington has found that zinc is integral in cancer prevention, particularly cancer of the esophagus. By the way, previous research had determined the importance of zinc and its protective effect for the esophagus; however, scientists were never sure exactly why this was so. Researchers out of the UTA College of Nursing and Health Innovation partnered with an experienced esophageal cancer researcher. Their efforts determined that zinc actually targets esophageal cancer cells while leaving normal cells alone. It seems that it works by impeding overactive calcium signaling in the cancer cells, which isn't a problem in normal cells. In this way, zinc inhibits cancer selectively, only in the cells that are exhibiting this behavior. Supplementation of just 15 mg of zinc daily has been found to improve T-cell functioning and increase the body's ability to fight infection, according University of Florida researchers.  Harm from blue light exposure increases with age, research suggests Oregon State University, July 27, 2022 The damaging effects of daily, lifelong exposure to the blue light emanating from phones, computers and household fixtures worsen as a person ages, new research by Oregon State University suggests. The study, published today in Aging, involved Drosophila melanogaster, the common fruit fly, an important model organism because of the cellular and developmental mechanisms it shares with other animals and humans. Jaga Giebultowicz, a researcher in the OSU College of Science who studies biological clocks, led a collaboration that examined the survival rate of flies kept in darkness and then moved at progressively older ages to an environment of constant blue light from light-emitting diodes, or LEDs. The darkness-to-light transitions occurred at the ages of two, 20, 40 and 60 days, and the study involved blue light's effect on the mitochondria of the flies' cells. “The novel aspect of this new study is showing that chronic exposure to blue light can impair energy-producing pathways even in cells that are not specialized in sensing light,” Giebultowicz said. “We determined that specific reactions in mitochondria were dramatically reduced by blue light, while other reactions were decreased by age independent of blue light. You can think of it as blue light exposure adding insult to injury in aging flies.” The scientists note that natural light is crucial for a person's circadian rhythm—the 24-hour cycle of physiological processes such as brain wave activity, hormone production and cell regeneration that are important factors in eating and sleeping patterns. But there is evidence suggesting that increased exposure to artificial light is a risk factor for sleep and circadian disorders, Giebultowicz said. And with the prevalent use of LED lighting and device displays, humans are subjected to increasing amounts of light in the blue spectrum since commonly used LEDs emit a high fraction of blue light. In the earlier research, flies subjected to daily cycles of 12 hours in light and 12 hours in darkness had shorter lives compared to flies kept in total darkness or those kept in light with the blue wavelengths filtered out. The flies exposed to blue light showed damage to their retinal cells and brain neurons and had impaired locomotion—the flies' ability to climb the walls of their enclosures, a common behavior, was diminished. Amla Extract May Boost Endotheial Function, Immune Response and More Nizam Institute of Medical Sciences (India), July 18, 2022 Endothelial dysfunction (ED) has been observed in individuals with metabolic syndrome (MetS) and contributes to the initiation and progression of atherosclerosis. The primary management of MetS involves lifestyle modifications and treatment of its individual components with drugs all of which have side effects. Thus, it would be of advantageous if natural products would be used as adjuncts or substitutes for conventional drugs. The aim of the present study was to evaluate the effect of standardized aqueous extract of fruits of amla (P. emblica) 250 mg and 500 mg twice daily on ED, oxidative stress, systemic inflammation and lipid profile in subjects with MetS. Out of 65 screened subjects all 59 enrolled completed the study. Amla aqueous extract (PEE), 250 mg and 500 mg twice daily dosing, showed significant reduction in mean RI, measure of endothelial function, at 8 and 12 weeks compared to baseline and placebo. PEE 500 mg twice daily was significantly more efficacious than the 250 mg twice daily and placebo. No participant discontinued the study because of adverse events. Amla aqueous extract significantly improved endothelial function, oxidative stress, systemic inflammation and lipid profile at both dosages tested, but especially at 500 mg twice daily. Thus, this product may be used as an adjunct to conventional therapy (lifestyle modification and pharmacological intervention) in the management of metabolic syndrome. Histamine-producing gut bacteria can trigger chronic abdominal pain McMaster University and Queen's University (Ontario), July 27 ,2022 Researchers from McMaster University and Queen's University have discovered a gut bacterial “super-producer” of histamine that can cause pain flare-ups in some patients with irritable bowel syndrome (IBS). The culprit is what has now been named Klebsiella aerogenes, identified in up to 25 percent of gut microbiota samples from patients with IBS. Researchers examined stool microbiota samples from both Canadian and American patient cohorts. “We followed up these patients for several months and found high levels of stool histamine at the time when the patients reported severe pain, and low stool histamine when they were pain-free,” said senior author Premysl Bercik, professor of medicine of McMaster's School of Medicine. The McMaster-Queen's research team pinpointed the bacterium Klebsiella aerogenes as the key histamine producer by studying germ-free mice colonized with gut microbiota from patients with IBS. They also colonized some mice with gut microbiota from healthy volunteers as a control group. The study found that the bacterium Klebsiella aerogenes converts dietary histidine, an essential amino acid present in animal and plant protein, into histamine, a known mediator of pain. The bacterial histamine then activates the gut immune system through histamine-4 receptor, which draws immune mast cells into the intestines. These activated mast cells produce even more histamine and other pain-signaling mediators, triggering inflammation and pain. The study found that when the mice colonized with histamine producing bacteria were fed a diet low in fermentable carbohydrates, bacterial histamine production dramatically decreased. This was due to change in bacterial fermentation and acidity within the gut, which inhibited the bacterial enzyme responsible for histamine production. Bercik said that these results explain the beneficial effects of a low fermentable diet observed in patients with IBS. Eating more ultra-processed foods associated with increased risk of dementia Tianjin Medical University (China), July 27, 2022 People who eat the highest amounts of ultra-processed foods like soft drinks, chips and cookies may have a higher risk of developing dementia than those who eat the lowest amounts, according to a new study published in the online issue of Neurology. Researchers also found that replacing ultra-processed foods in a person's diet with unprocessed or minimally processed foods was associated with a lower risk. The study does not prove that ultra-processed foods cause dementia. It only shows an association. Ultra-processed foods are high in added sugar, fat and salt, and low in protein and fiber. They include soft drinks, salty and sugary snacks, ice cream, sausage, deep-fried chicken, yogurt, canned baked beans and tomatoes, ketchup, mayonnaise, packaged guacamole and hummus, packaged breads and flavored cereals. For the study, researchers identified 72,083 people from the UK Biobank, a large database containing the health information of half a million people living in the United Kingdom. Participants were age 55 and older and did not have dementia at the start of the study. They were followed for an average of 10 years. By the end of the study, 518 people were diagnosed with dementia. Researchers determined how much ultra-processed food people ate by calculating the grams per day and comparing it to the grams per day of other foods to create a percentage of their daily diet. They then divided participants into four equal groups from lowest percentage consumption of ultra-processed foods to highest. After adjusting for age, gender, family history of dementia and heart disease and other factors that could affect risk of dementia, researchers found that for every 10% increase in daily intake of ultra-processed foods, people had a 25% higher risk of dementia. Researchers also used study data to estimate what would happen if a person substituted 10% of ultra-processed foods with unprocessed or minimally processed foods, like fresh fruit, vegetables, legumes, milk and meat. They found that such a substitution was associated with a 19% lower risk of dementia. “Our results also show increasing unprocessed or minimally processed foods by only 50 grams a day, which is equivalent to half an apple, a serving of corn, or a bowl of bran cereal, and simultaneously decreasing ultra-processed foods by 50 grams a day, equivalent to a chocolate bar or a serving of fish sticks, is associated with 3% decreased risk of dementia,” said Li. “It's encouraging to know that small and manageable changes in diet may make a difference in a person's risk of dementia.”

It's the first tribally-affiliated college of medicine ever to open in the US; it launched in August of 2020 with an entering class of 54 first-year medical students.

People may think of Vermont when they think maple syrup. But could there be an untapped commercial industry in the Pacific Northwest? Eric T. Jones is an assistant professor of practice in the OSU College of Forestry and is leading a project on bigleaf maple sap in Western Oregon. He joins us with details.

The OSU College of Nursing is currently recruiting participants for a research project exploring pain in Alzheimer's disease.My guests include my longtime friend Michelle Crum who is a Research Recruitment Specialist at The Ohio State University. Plus, Karon Ross, PhD, RN, CNL and Assistant Professor at The Ohio State University is at the table. She is the principal investigator in this very important study.We really encourage you to participate in this study if you are over 60, and within a 2 hour drive of The Ohio State University. You can reach Michelle at crum.257@osu.edu or call her at (614) 292-0226.Here is a link to the article Michelle and I talk about in this episode.https://www.theatlantic.com/health/archive/2021/02/alzheimers-dementia-pain-memory/617994/Email me, Lisa Stockdale, anytime at aginginfullbloom@gmail.comAging In Full Bloom is sponsored by Capital Health Care Network, an Ohio based, family owned and operated company, providing solutions that help seniors age on their own terms. Those solutions include home care, senior living, nursing home and rehab care, and hospice. Learn more at http://www.CapitalHealthCareNetwork.com. Follow the podcast on Apple Podcasts, Google Podcasts, iTunes, Stitcher, or your favorite podcast player. Android user? http://www.subscribeonandroid.comHELP US SPREAD THE WORD!We'd love it if you could please share this podcast with your social media friends! If you liked this episode, please leave us a rating and a review in your podcast player.

Today we welcome the fabulous Karen Daw also known as The Osha Lady!  Karen is an award-winning national speaker, author of numerous articles and CE courses on safety in dentistry, and a trainer for practices and healthcare systems across the United States. She earned her BA from the Ohio State University and her MBA with concentrations in Healthcare Administration and Business Management. After graduating, Karen was recruited from the Emergency Department to her roles as Assistant Director of Sterilization Monitoring and Health and Safety Director for the OSU College of Dentistry.  She is a proud member of the Organization for Safety Asepsis and Prevention, where she also served as co-chair for their Annual Conference and Infection Control Boot Camp. This episode is generously sponsored by our peeps at the Hu-Friedy group! As dental professionals, our PPE is necessary for the safety of both our patients and team members throughout the practice.  In regard to the masks we wear though, it's not one size fits all and when we talk about protection and infection control the fit is everything! That is where the Hu-Friedy Secure Fit masks come in! Irene uses these exclusively in her practice! Secure Fit masks feature aluminum nose and chin pinch mechanisms at the top over the nose and also at the bottom under the chin to help reduce gapping. This allows the wearer to customize the mask to their face for optimal fit and protection without sacrificing comfort! And when industry experts are recommending that we change our masks every 20 minutes during procedures with heavy fluid and aerosol exposure to avoid wicking, we could use something with a comfortable fit! Am I right?!  Learn more about Secure Fit masks at the link below as well as the link to the Friends of Hu-Friedy blog! https://www.hufriedygroup.com/securefit   Friends of Hu-Friedy ___________________________________________________ In today's episode, Karen discusses with Irene and Katrina how she got into OSHA and dentistry including how she decided to go out on her own with her business and her approach to get people excited when learning about workplace safety! They talk about what OSHA actually is and how it parallels with Canada's WHMIS, and what trainings are mandatory for US dental practices as well as who in the office should be required to train. She discusses the importance of building a culture of safety within your practice and what she recommends when it comes to having difficult conversations regarding safety practices and compliance. Lastly, she shares a story of one of the worst things she's encountered on the job and how she has pivoted her business during the Covid-19 pandemic! We think you'll love her as much as we do!   Reach out to Karen at: Theoshalady.com Karendaw.com   On Instagram @theoshalady ___________________________________________________   Our hosts encourage you to leave them a review!   Find more episodes at https://www.toothordare.ca/   Follow us on Instagram! Podcast: @toothordare.podcast Irene: @toothlife.irene Katrina: @thedentalwinegenist

Virologists reveal how poor man's amino acid cure for COVID-19 would abolish need for vaccines Bio-Virus Research Inc (Nevada), September 15, 2021 A natural cure for COVID-19 that is widely available and affordable for even the poorest of people on the planet has been confirmed by a team of virologists who have spent a lifetime studying the underlying causes of viral infections. Backed by decades of research and safety data for herpes-family viruses, U.S.-based researchers at Bio-Virus Research Inc, Reno, Nevada, report on the successful treatment of the first 30 frontline doctors and nurses and a thousand-plus patients given the amino acid lysine to prevent and even abolish COVID-19 coronavirus infections at a clinic in the Dominican Republic.  Astonishingly, symptoms of COVID-19 are reported to have dissipated within hours of this natural treatment. The medical staff at a clinic in the Dominican Republic was coming down with two cases of coronavirus per month before lysine therapy was instituted. The virologists, Drs. Christopher Kagan, Bo Karlicki and Alexander Chaihorsky, strongly suggested the front-line healthcare workers embark on a daily regimen of lysine therapy due to daily exposure to the virus.  Their ground-breaking report is published online at ResearchGate.net. Arginine/lysine balance Lysine therapy interrupts the replication of viruses, including COVID-19 coronavirus, by countering arginine, an amino acid that fosters the eruption of dormant viruses.  Lysine has been safely used for decades to quell herpes virus outbreaks that cause cold sores on the lips (herpes labialis), a treatment pioneered by one of the Bio-Virus Research team members in 1974. Lysine is available in foods and in concentrated form in inexpensive dietary supplements (250 500-milligram lysine tablets can be purchased for under $5 US or 2-cents per tablet), making affordable lysine therapy possible. Lysine/arginine imbalance would explain why patients who have been infected with COVID-19 have recurrent infections, even after vaccination. Lysine Rx in Dominican Republic The daily therapeutic supplement regimen for the medical staff in the Dominican Republic consisted of 2000 milligrams of lysine capsules along with restricted dietary consumption of arginine-rich foods such as nuts, chocolate, orange juice, pumpkin, sesame seeds, wheat germ. The Bio-Virus Research team found doses of supplemental lysine up to 4000 milligrams to be safe and effective. Foods that have a high ratio of lysine over arginine such as eggs, tofu, fish (not raw), sardines, cheese, meats such as pork, poultry and red meat, and yogurt) provide a high ratio of lysine over arginine, thus blocking replication of all coronaviruses including COVID-19. According to the virologists who were interviewed by this reporter, over 1000 patients have now been successfully treated with surprisingly rapid dissolution of symptoms and return to health.  Even severely infected COVID-19 patients have been able to come off the ventilator with lysine therapy, say doctors. Third-party validation for lysine therapy Writing in the International Journal of Infectious Diseases another research team based in New York and Texas reports that arginine depletion is a strategy to quell both coronaviruses and other herpes family viruses. In 2016 researchers documented that lysine impairs the growth of coronaviruses in a lab dish. The Bio-Virus Research team are not loners nor out on a scientific limb.  A report, published in the Journal of Antivirals & Antiretrovirals, is what prompted to the current discovery that was put into clinical practice in the Dominican Republic.  The science was in place prior to the announcement a mutated coronavirus was sweeping the globe which no one had immunity towards. Dietary intake The Recommended Daily dietary intake of lysine is 2660 milligrams for a 154-lb (70 kilogram) adult; 3640 milligrams during pregnancy. Dietary intake of lysine in western populations ranges from 40-180 milligrams per day per kilogram (2.2 lbs.) of body weight, or 2800-12,600 milligrams for a 154 lb. (70 kilogram) adult. It is the balance of arginine to lysine that controls the eruption of dormant viruses in the body.  The average intake of arginine is estimated to be 4000-6000 milligrams per day. Other health benefits Supplemental lysine also has other health benefits.  Lysine increases absorption of calcium, relieves bouts of anxiety, promotes wound healing, and is helpful for other conditions.  Cholesterol is deposited in binding sites within coronary arteries.  When lysine (and vitamin C) occupy those binding sites, cholesterol is not deposited in arteries. Prevalence of herpes viral infections Worldwide many billions of people harbor dormant herpes viruses that erupt into disease from time to time.  In 2016 an estimated 3.7 billion people had herpes simplex virus infection– around 66.6% of the world's population aged 0 to 49. Availability of lysine Lysine is largely produced by the tons for animal feedstuffs.  Roughly 2,200,000 tons of lysine are produced annually.  There is no shortage. Billions may benefit The most frequent medical application of lysine therapy has been the quelling of active herpes infections (on skin, lips, etc.), and eradication of Epstein-Barr infection, Bell's palsy, etc. Researchers bemoan the fact that lysine therapy hasn't become a mainstay in the treatment of herpes infections that affect ~80% of the world's population over expensive and problematic anti-viral drugs because it doesn't generate sufficient profit to attract funding for human clinical trials.  Lysine is superior to various anti-viral drugs. If lysine lives up to its promise as a universal COVID-19 antidote for therapeutic and preventive use, unless billionaire Bill Gates buys up and mothballs all the lysine production plants in the world like he has bought off agricultural land, and bought off news media, vaccine makers and politicians, the need for vaccines will become a moot and meaningless practice for COVID-19. Because of the long-term safety record of this dietary amino acid, the public can take lysine as a non-prescription preventive “medicine.” Epidemiologists baffled by low rate of coronavirus infections in India Despite its large population and poor sanitation, disease trackers are baffled by India's low rate of coronavirus infections.  Maybe it is India's lysine-rich diet of yogurt, lamb, chicken, fish curry that protects its population from viral disease.  The striking difference in the country-to-country prevalence of Herpes Simplex-2 infections (only 9.6% in South East Asian countries and 10.7% in Europe vs. 24.0% in the Americas and 43.9% in Africa) could be explained by the lysine/arginine ratio in native diets. Treat the severely ill; skip the problematic vaccines Vaccination is not fool proof.  Vaccinated patients are testing positive for COVID-19.  Doctors can choose to treat the 3 in 10,000 COVID-19 severely infected patients who are at risk for a mortal outcome with lysine rather than needlessly vaccinate billions of people.  Mass vaccination would not be needed, nor would lockdowns, quarantines and questionable mass face mask use be required.  The pandemic would be rapidly extinguished by a public information campaign regarding lysine-rich foods and dietary supplements.  The public can take action on its own today without adverse consequences.  Literally, trillions of dollars would be saved worldwide.  If not for COVID-19, at least for herpes infections. The shame is on the World Health Organization with a budget of $8.482 billion or the Centers For Disease Control with a budget of $7.875 billion that overlook safe and economical cures like lysine.  This report serves as evidence the world is being gamed to plunder the masses of their health and wealth.  The people of the world need to stop heeding advice from public health officials and practice preventive medicine on their own volition. There is additional evidence that lysine also halts the growth of influenza and coxsackie viruses. Further research Researchers at Bio-Virus Research Inc. are searching for research funds to further document the benefits of lysine therapy.      Omega-3 and Omega-6 supplement improves reading for children   University of Gothenburg, Sweden - September 14, 2021    Supplement of omega-3 and omega-6 fatty acids may improve reading skills of mainstream schoolchildren, according to a new study from Sahlgrenska Academy, at the University of Gothenburg, Sweden. Children with attention problems, in particular, may be helped in their reading with the addition of these fatty acids.   The study included 154 schoolchildren from western Sweden in grade 3, between nine and ten years old. The children took a computer-based test (known as the Logos test) that measured their reading skills in a variety of ways, including reading speed, ability to read nonsense words and vocabulary.   The children were randomly assigned to receive either capsules with omega-3 and omega-6, or identical capsules that contained a placebo (palm oil) for 3 months. The children, parents and researchers did not learn until the study was completed which children had received fatty acids and which had received the placebo. After three months, all children received real omega-3/6 capsules for the final three months of the study.   "Even after three months, we could see that the children's reading skills improved with the addition of fatty acids, compared with those who received the placebo. This was particularly evident in the ability to read a nonsense word aloud and pronounce it correctly (phonologic decoding), and the ability to read a series of letters quickly (visual analysis time)," says Mats Johnson, who is chief physician and researcher at the Gillberg Neuropsychiatry Centre at Sahlgrenska Academy, University of Gothenburg.   No children diagnosed with ADHD were included in the study, but with the help of the children's parents, the researchers could identify children who had milder attention problems. These children attained even greater improvements in several tests, including faster reading already after three months of receiving fatty acid supplements.   Polyunsaturated fats and their role in children's learning and behavior is a growing research area.   "Our modern diet contains relatively little omega-3, which it is believed to have a negative effect on our children when it comes to learning, literacy and attention," says Mats Johnson. "The cell membranes in the brain are largely made up of polyunsaturated fats, and there are studies that indicate that fatty acids are important for signal transmission between nerve cells and the regulation of signaling systems in the brain."   Previous studies in which researchers examined the effect of omega-3 as a supplement for mainstream schoolchildren have not shown positive results, something Mats Johnson believes may depend on how these studies were organized and what combination and doses of fatty acids were used. This is the first double-blind, placebo-controlled study showing that omega-3/6 improves reading among mainstream schoolchildren.   "Our study suggests that children could benefit from a dietary supplement with a special formula. To be more certain about the results, they should also be replicated in other studies," says Mats Johnson. The article Omega 3/6 fatty acids for reading in children: a randomized, double-blind, placebo-controlled trial in 9-year-old mainstream schoolchildren in Sweden was published by The Journal of Child Psychology and Psychiatry.       Elevated stress hormones linked to higher risk of high blood pressure and heart events Kyoto University (Japan) & University of California at Los Angeles, Sept. 13, 2021  Adults with normal blood pressure and high levels of stress hormones were more likely to develop high blood pressure and experience cardiovascular events compared to those who had lower stress hormone levels, according to new research published today in Hypertension, an American Heart Association journal. Studies have shown that cumulative exposure to daily stressors and exposure to traumatic stress can increase cardiovascular disease risk. A growing body of research refers to the mind-heart-body connection, which suggests a person's mind can positively or negatively affect cardiovascular health, cardiovascular risk factors and risk for cardiovascular disease events, as well as cardiovascular prognosis over time. “The stress hormones norepinephrine, epinephrine, dopamine and cortisol can increase with stress from life events, work, relationships, finances and more. And we confirmed that stress is a key factor contributing to the risk of hypertension and cardiovascular events,” said study author Kosuke Inoue, M.D., Ph.D., assistant professor of social epidemiology at Kyoto University in Kyoto, Japan. Inoue also is affiliated with the department of epidemiology at the Fielding School of Public Health at the University of California, Los Angeles. “Previous research focused on the relationship between stress hormone levels and hypertension or cardiovascular events in patients with existing hypertension. However, studies looking at adults without hypertension were lacking,” Inoue said. “It is important to examine the impact of stress on adults in the general population because it provides new information about whether routine measurement of stress hormones needs to be considered to prevent hypertension and CVD events.” Study subjects were part of the MESA Stress 1 study, a substudy of the Multi-Ethnic Study of Atherosclerosis (MESA), a large study of atherosclerosis risk factors among more than 6,000 men and women from six U.S. communities. As part of MESA exams 3 and 4 (conducted between July 2004 and October 2006), white, Black and Hispanic participants with normal blood pressure from the New York and Los Angeles sites were invited to participate in the substudy MESA Stress 1. In this substudy, researchers analyzed levels of norepinephrine, epinephrine, dopamine and cortisol – hormones that respond to stress levels. Hormone levels were measured in a 12-hour overnight urine test. The substudy included 412 adults ages 48 to 87 years. About half were female, 54% were Hispanic, 22% were Black and 24% were white. Participants were followed for three more visits (between September 2005 and June 2018) for development of hypertension and cardiovascular events such as chest pain, the need for an artery-opening procedure, or having a heart attack or stroke. Norepinephrine, epinephrine and dopamine are molecules known as catecholamines that maintain stability throughout the autonomic nervous system—the system that regulates involuntary body functions such as heart rate, blood pressure and breathing. Cortisol is a steroid hormone released when one experiences stress and is regulated by the hypothalamic-pituitary-adrenal axis, which modulates stress response.  “Although all of these hormones are produced in the adrenal gland, they have different roles and mechanisms to influence the cardiovascular system, so it is important to study their relationship with hypertension and cardiovascular events, individually,” Inoue said.  Their analysis of the relationship between stress hormones and development of atherosclerosis found: Over a median of 6.5-year follow-up period, every time the levels of the four stress hormones doubled was associated with a 21-31% increase in the risk of developing hypertension. During a median of 11.2-years of follow-up, there was a 90% increased risk of cardiovascular events with each doubling of cortisol levels. There was no association between cardiovascular events and catecholamines. “It is challenging to study psychosocial stress since it is personal, and its impact varies for each individual. In this research, we used a noninvasive measure — a single urine test — to determine whether such stress might help identify people in need of additional screening to prevent hypertension and possibly cardiovascular events,” Inoue said. "The next key research question is whether and in which populations increased testing of stress hormones could be helpful. Currently, these hormones are measured only when hypertension with an underlying cause or other related diseases are suspected. However, if additional screening could help prevent hypertension and cardiovascular events, we may want to measure these hormone levels more frequently.” A limitation of the study is that it did not include people who had hypertension at the study's start, which would have resulted in a larger study population. Another limitation is that researchers measured stress hormones via a urine test only, and no other tests for stress hormone measurement were used.   Spirulina alleviates high fat diet-induced cognitive impairment via the gut-brain axis Weifang People's Hospital (China), September 9, 2021 Increasing evidence suggested that the gut microbiome-brain axis plays a critical role in regulating cognitive functions. In this study, we aimed to investigate the dietary treatment effect of Spirulina platensis on learning deficits in high fat diet (HFD) fed mice and clarify the potential mechanisms via investigating the gut microbiome-brain axis. Dietary administration of 1% and 2% Spirulina platensis for 16 weeks significantly improved the spatial learning and memory performance of the HFD-fed mice in both Barnes Maze test and Morris water maze test. The Aβ accumulation, tau-hyperphosphorylation, and neuroinflammation in the hippocampus were significantly inhibited by Spirulina platensis. Spirulina platensis also abrogated HFD induced gut microbial dysbiosis and unbalance of gut microbial metabolites indicating its modulating effect on the gut-brain axis. This study provides further evidence for the application of Spirulina platensis as functional supplement for treatment of Alzheimer's disease. Spirulina platensis was frequently used as both a food ingredient and a medical supplement to counteract various metabolic disorders worldwide. In the present study, we found that Spirulina platensis dietary supplementation significantly prevented the cognitive deficits induced by HFD- feeding in mice. For the first time, we identified the inhibition effect of Spirulina platensis on β-amyloid generation, tau-hyperphosphorylation, neuroinflammation, and the gut microbiota dysbiosis. In conclusion, the present study proved the beneficial effect of Spirulina platensis on cognitive impairment in HDF-fed AD mice and cleared Aβ, inhibited tau-hyperphosphorylation, and ameliorated neuroinflammation in the brain. Spirulina platensis also abrogated HFD induced gut microbial dysbiosis and unbalance of gut microbial metabolites indicating that Spirulina platensis might ameliorated cognitive deficits through regulating the gut-brain axis (Fig. 6). This study provides potent evidence for the application of Spirulina platensis as functional supplement for treatment of AD.   Regular exercise may lower risk of developing anxiety by almost 60% University of Lund (Sweden), September 13, 2021 A quick online search for ways to improve our mental health will often come up with a myriad of different results. However, one of the most common suggestions put forward as a step to achieving wellness—and preventing future issues—is doing some physical exercise, whether it be a walk or playing a team sport. Anxiety disorders—which typically develop early in a person's life—are estimated to affect approximately 10% of the world's population and has been found to be twice as common in women compared to men. And while exercise is put forward as a promising strategy for the treatment of anxiety, little is known about the impact of exercise dose, intensity or physical fitness level on the risk of developing anxiety disorders. To help answer this question, researchers in Sweden have published a study in Frontiers in Psychiatry to show that those who took part in the world's largest long-distance cross-country ski race (Vasaloppet) between 1989 and 2010 had a "significantly lower risk" of developing anxiety compared to non-skiers during the same period. The study is based on data from almost 400,000 people in one of the largest ever population-wide epidemiology studies across both sexes. Surprising finding among female skiers "We found that the group with a more physically active lifestyle had an almost 60% lower risk of developing anxiety disorders over a follow-up period of up to 21 years," said first author of the paper, Martine Svensson, and her colleague and principal investigator, Tomas Deierborg, of the Department of Experimental Medical Science at Lund University, Sweden. "This association between a physically active lifestyle and a lower risk of anxiety was seen in both men and women." However, the authors found a noticeable difference in exercise performance level and the risk of developing anxiety between male and female skiers. While a male skier's physical performance did not appear to affect the risk of developing anxiety, the highest performing group of female skiers had almost the double risk of developing anxiety disorders compared to the group which was physically active at a lower performance level. "Importantly," they said, "the total risk of getting anxiety among high-performing women was still lower compared to the more physically inactive women in the general population". These findings cover relatively uncharted territory for scientific research, according to the researchers, as most previous studies focused on depression or mental illness as opposed to specifically diagnosed anxiety disorders. Furthermore, some of the largest studies looking at this topic only included men, were much smaller in sample size, and had either limited or no follow-up data to track the long-term effects of physical activity on mental health. Next steps for research The surprising discovery of an association between physical performance and the risk for anxiety disorders in women also emphasized the scientific importance of these findings for follow-up research. "Our results suggest that the relation between symptoms of anxiety and exercise behavior may not be linear," Svensson said. "Exercise behaviors and anxiety symptoms are likely to be affected by genetics, psychological factors, and personality traits, confounders that were not possible to investigate in our cohort. Studies investigating the driving factors behind these differences between men and women when it comes to extreme exercise behaviors and how it affects the development of anxiety are needed." They added that randomized intervention trials, as well as long-term objective measurements of physical activity in prospective studies, are also needed to assess the validity and causality of the association they reported. But does this mean that skiing in particular can play an important role in keeping anxiety at bay, as opposed to any other form of exercise? Not so, Svensson and Deierborg said, given that previous studies have also shown the benefits of keeping fit on our mental health. "We think this cohort of cross-country skiers is a good proxy for an active lifestyle, but there could also be a component of being more outdoors among skiers," they said. "Studies focusing on specific sports may find slightly different results and magnitudes of the associations, but this is most likely due to other important factors that affect mental health and which you cannot easily control in research analysis.   Gut microbes are key to health benefit delivered by hops compound Oregon State University, September 13, 2021 The health-enhancing performance of a compound found in hops is dependent upon its interactions with intestinal microorganisms, new research by Oregon State University shows. Understanding how xanthohumol, often abbreviated as XN, works is important for unlocking its potential to counter diet-induced obesity and the health risksassociated with a global obesity epidemic, including type 2 diabetes and liver and heart disease, researcher Adrian Gombart says. "We showed that the gut microbiota are necessary for the beneficial effects of XN on glucose metabolism," said Gombart, professor of biochemistry and biophysics in the OSU College of Science and a principal investigator at the university's Linus Pauling Institute. "There is an important interaction between the compound and the microbes in the gut that provides the benefits we see in our studies with mice." Gombart led a team of 20 scientists from three Oregon State colleges in research that compared the glucose metabolism effects of xanthohumol on two sets of mice: "conventional" ones with gut microbiota, and those engineered to be "germ free," i.e. have no gut microbes. Glucose metabolism, the body's ability to convert the sugar into fuel, generally suffers impairment as someone becomes obese, which in turn can lead to the person becoming more overweight. Faulty glucose metabolism also negatively affects brain physiology and is at the root of multiple medical conditions including diabetes and heart disease. In previous studies involving mice, Gombart and colleagues found that XN improved the animals' health and changed the composition of their microbiome, the latter leading them to suspect that the mix of microbes played a role in XN's healthful effects. "In this study, we fed mice either a diet low in calories, high in calories, or high in calories but supplemented with XN for 10 weeks," he said. "We found that only the conventional mice with XN supplementation showed improved glucose metabolism and that XN increased the relative abundance of three bacteria, Akkermansia muciniphila, Parabacteroides goldsteinii and Alistipes finegoldii." Gombart added that the study yielded some evidence that those three microbes are at least partially responsible for the health benefits associated with XN, but the entire microbial community may be playing a role as well. "We can't rule that out," he said. "We know that XN needs the intestinal microbiota to deliver its benefits, and there are complex diet-host-microbiota interactions that bring changes in both microbial composition and functional capacity. Diet is recognized as a major force in shaping gut microbe composition, and future studies will look for insights into the various interactions at play." Earlier mouse model studies by co-author Fred Stevens, professor of pharmaceutical sciences in the OSU College of Pharmacy and also a principal investigator at the Linus Pauling Institute , have shown that XN, a polyphenol found in hops' cones, has a number of anti-obesity properties. It improves cognitive function and it suppresses weight gain associated with a high-fat diet, fat accumulation in adipose tissue and insulin resistance. Insulin resistance is when cells don't respond well to the hormone that allows for the uptake of glucose from the bloodstream. It causes the pancreas to make more and more insulin to keep blood glucose levels within a non-harmful range and is a risk factor for non-alcoholic fatty liver disease.   Antioxidant protects neurons   University of Edinburgh   September 12 2021    Research involving a potent antioxidant, described in Scientific Reports, suggests that the compound could help protect cells in several conditions, including Parkinson's disease, multiple sclerosisand cell transplants. In their report, a team from the University of Edinburgh observe that the flavonoids quercetin and myricetin are among the most potent dietary antioxidants. Structural modification of myricetin has resulted in the development a new compound known as Proxison. In the current research, Proxison demonstrated 10 times the ability to protect against oxidative stress induced by the compound tert-Butyl hydroperoxide (tBHP) in neuroblastoma cells compared to quercetin, while several other antioxidants showed no effects. Proxison, as well as a high concentration of quercetin, also provided significant protection against cell death in tBHP-treated cells. Similar results were obtained in another neural cell line. An investigation of the antioxidants' ability to be taken up by the cells showed significant intracellular levels of quercetin and Proxison, and evidence for some localization of Proxison in the cells' mitochondria. In zebrafish embryos, Proxison helped protect against neuronal cell loss induced by a neurotoxic compound. Quercetin was also protective, but was less potent than Proxison. Neither therapy affected normal embryonic development. “This novel antioxidant can be applied to investigate oxidative stress in disease models, like alpha-synucleinopathies and other neurodegeneration models,” Nicola J. Drummond and colleagues conclude. “In addition, Proxison could have applications for regenerative medicine where oxidative stress has been implicated in poor cell survival of transplanted cells, with the advantage that the molecule can be pre-loaded into cells prior to transplantation. Proxison could also have applications for conditions, such as stroke or cardiac infarction, in which a temporary, but acute, exposure to oxidative stress is experienced, as well as diseases in which oxidative stress and mitochondrial dysfunction are core features.”

On this episode of Leadership Lessons in Health-System Pharmacy you will hear from Marialice S. Bennett, RPh, FAPhA, recipient of the 2021 Remington Honor Medal, the highest honor bestowed by the American Pharmacists Association (APhA) and the profession's highest recognition. Marialice S. Bennett, RPh, FAPhA, BSPharm '69, is a Professor Emerita of Pharmacy Practice and Science and former Residency Director for The Ambulatory and Community Care Residency Programs at the Ohio State University (OSU) College of Pharmacy. She earned her BS degree from The OSU College of Pharmacy in 1969. Professor Bennett is recognized as a practice innovator and an agent of change. She was among the first clinical pharmacists to practice at the OSU Medical Center. Later, her practice team's contributed to the development of both the OSU College of Pharmacy Clinical Partners Program and the OSU University Health Connection, an innovative interprofessional health care clinic for faculty and staff of the university. She has been involved with several national practice-based research projects including Project Impact: Hyperlipidemia and Patient Self-Management: Diabetes. Professor Bennett loves to teach and to mentor. She strives to bring innovation and inspiration to all learners. Over the past 30 years she has contributed to the advancement of community residencies nationally and leaves a legacy of cutting-edge residency programs at OSU. She feels blessed to have mentored numerous practitioners, residents, and students during her career. Her service includes 2011-12 APhA President; 2007-2009 President of APhA-APPM and member of the APhA Board of Trustees; 2016-present Ohio Pharmacists Association Foundation Board, and contributor to numerous initiatives related to practice innovation and community residencies. Marialice and her husband, Jon, are grateful for their three sons and their families: Jay and Cayenne; Vincent, Stephanie, Jaxon, Tyson, and Lulu Rose; and Bryan, Jessica, Josie, and Hudson. This episode's guest was interviewed by Lauren M. Aschermann, PharmD, MS, BCPS, a 2021 graduate of OSU's MS-HSPAL program. Dr. Aschermann recently accepted a position at the University of Wisconsin (UW Health) as Pharmacy Manager, Pediatrics (American Family Children's Hospital), Adult Surgery and Nutrition Support.

Evaluation of ischemic stroke, decisions for tPA and thrombectomy, supportive critical care, and monitoring for cerebral edema—with returning guest Thomas Lawson (@TomLawsonNP), nurse practitioner in the neurocritical care unit at OSU Wexner Medical Center and James Cancer Hospital. Thomas is now also a PhD student at the OSU College of Nursing where he studies the … Continue reading "Episode 33: Ischemic stroke with Thomas Lawson"

In this episode, our guest is Marialice Bennett, a former APhA Past President and the 2021 APhA Remington Medal recipient. Marialice is a Professor Emerita of Pharmacy Practice and Science and former Residency Director for The Ambulatory and Community Care Residency Programs at the Ohio State University College of Pharmacy. She served as a co-founder and pharmacy director of University Health Connection, an innovative interprofessional health care clinic for faculty and staff of the university, from 1999 to 2011. She currently works with the American Pharmacists Association (APhA) and with the American Society of Health-Systems Pharmacists (ASHP) to advance community-based pharmacy practice and community-based residency programs. She earned her BS degree from The Ohio State University College of Pharmacy in 1969. Professor Bennett is recognized as a practice innovator and an agent of change. She was among the first clinical pharmacists to practice at the OSU Medical Center. Her practice team's contribution to the development of both the OSU College of Pharmacy Clinical Partners and the OSU University Health Connection resulted in 2005 and 2006 ASHP Best Practice Awards. She received the 1999 APhA Daniel B. Smith Practice Excellence Award for her contributes to practice, the 2011 OPA Beal Award for lifetime contributions to pharmacy, 2015 OSU College of Pharmacy Lifetime Achievement Award, and the 2016 Bowl of Hygeia Award for service to the community. She has been involved with several national practice-based research projects including Project Impact: Hyperlipidemia and Patient Self-Management: Diabetes. She has contributed to numerous projects and tools developed to implement medication therapy management (MTM) nationally as well as frequently speaking and publishing on practice innovation. She received the 2004 APhA Foundation, Jake Miller Award for her contributions to practice-based research. Professor Bennett loves to teach and to mentor. She strives to bring innovation and inspiration to all learners. Over the past 30 years she has contributed to the advancement of community residencies nationally and leaves a legacy of cutting edge PGY1 and PGY2 programs at OSU. She feels blessed to have mentored 108 residents and numerous students during her career. She is honored to be the recipient of several OSU teaching awards, the 2004 APhA Community Pharmacy Residency Excellence in Precepting Award, 2009 APhA Gloria Niemeyer Franck Leadership Mentoring Award, the 2013 Linwood F. Tice Friend of APhA-ASP Award, and the 2016 OSU Alumni Society Josephine Sitterle Failer Award for volunteer service to students. Her service includes 2011-12 APhA President; 2007-2009 President of APhA-Academy of Pharmacy Practice and Management and member of the APhA Board of Trustees; and member of numerous task forces, panels, and commissions related to MTM, practice innovation, and community residencies. Topics covered: Community based practice has been your passion Teaching & mentoring Telling the story of being a woman and an innovator in pharmacy. Addressing past and current barriers to women in leadership. Advice for overcoming some of the current barriers. Guest - Marialice Bennett, BSPharm, RPh, FAPhA LinkedIn - https://www.linkedin.com/in/marialice-bennett-60b39011/ Host - Hillary Blackburn, PharmD, MBA www.hillaryblackburn.com https://www.linkedin.com/in/hillary-blackburn-67a92421/ @talktoyourpharmacist for Instagram and Facebook @HillBlackburn Twitter

On this episode of the Raving Patients Podcast, Len sits down with Karen Daw to discuss how to promote safety within your practice to your patients. There's no doubt we live in an interconnected age. That is, we have more access to information than any time in human history. With so much access to information, we seem to be losing the fine art of communication. And in the era of COVID-19, safety dialogue is more important than ever. By incorporating safety efforts in our communication, we will reassure patients visiting the dental practice is safe and maximize the appointment time with less turnover per chair while providing necessary care. Takeaways from this episode include:  What are ways we can accomplish communicating safety to our patients. Walking the walk - training required in IC and OSHA Resources to help practices perform as a high-level team in this area   Karen Daw is an award-winning national speaker, author of numerous articles and CE courses on safety in dentistry, and a trainer for practices and healthcare systems across the country. She earned her BA from the Ohio State University and her MBA with concentrations in Healthcare Administration and Business Management. After graduating, Karen was recruited from the Emergency Department to her roles as Assistant Director of Sterilization Monitoring and Health and Safety Director for the OSU College of Dentistry.   Karen is a proud member of the Organization for Safety Asepsis and Prevention, where she also served as co-chair for their Annual Conference and Infection Control Boot Camp.

Starting college is already tough, but imagine starting college without a family support system. That’s the reality for many foster children across the country. OStateTV’s Dallas Haggerty introduces us to “R is for Thursday”, which is designed to support foster youth and alumni both during and after college. Dallas sat down with Kerri Karney from the OSU College of Education and Human Sciences to find out more….

Starting college is already tough, but imagine starting college without a family support system.  That's the reality for many foster children across the country.  OStateTV's Dallas Haggerty introduces us to “R is for Thursday”, which is designed to support foster youth and alumni both during and after college.  Dallas sat down with Kerri Karney from the OSU College of Education and Human Sciences to find out more….

Dogs are diagnosed with cancer at about the same rate as people, but seem to tolerate chemotherapy and other treatments a little bit better. In this episode, we talk with Rustin Moore, Dean of The Ohio State University College of Veterinary Medicine. It's a fascinating discussion, as Rustin fills us in on cancer in cats and dogs. For example: The breeds with the highest cancer rates, and what types of cancers are most common. Rustin also discusses how members of the College of Veterinary Medicine collaborate with members of the James team on scores of clinical trials that benefit humans and our furry friends. "Team science is so important, and I have to give a shout out to the James for being so receptive to working with us," he says.

The Gary Null Show is here to inform you on the best news in health, healing, the environment. Multivitamin, mineral supplement linked to less-severe, shorter-lasting illness symptoms Oregon State University, August 18, 2020   Older adults who took a daily multivitamin and mineral supplement with zinc and high amounts of vitamin C in a 12-week study experienced sickness for shorter periods and with less severe symptoms than counterparts in a control group receiving a placebo. The findings by Oregon State University researchers were published in the journal Nutrients. The research by scientists at OSU's Linus Pauling Institute involved 42 healthy people ages 55 to 75 and was designed to measure the supplement's effects on certain immune system indicators. It also looked at bloodstream levels of zinc and vitamins C and D while taking the supplement, as these micronutrients are important for proper immune function. The immune indicators, including white blood cells' ability to kill incoming pathogens, were unaltered in the group receiving the supplement.  The multivitamin group showedimproved vitamin C and zinc status in the blood. Most intriguingly, illness symptoms reported by this group were less severe and went away faster than those experienced by the placebo group.  The same percentage of participants in each group reported symptoms, but days of sickness in the supplement group averaged fewer than three compared to more than six for the placebo group.  "The observed illness differences were striking," said corresponding author Adrian Gombart, professor of biochemistry and biophysics in the OSU College of Science and a principal investigator at the Linus Pauling Institute. "While the study was limited to self-reported illness data and we did not design the study to answer this question, the observed differences suggest that additional larger studies designed for these outcomes are warranted - and, frankly, overdue." As people get older, the risk of vitamin and mineral deficiencies that contribute to age-related immune system deficiencies rises. Across the United States, Canada and Europe, research suggests more than one-third of older adults are deficient in at least one micronutrient, often more than one. "That likely contributes to a decline in the immune system, most often characterized by increased levels of inflammation, reduced innate immune function and reduced T-cell function," Gombart said. "Since multiple nutrients support immune function, older adults often benefit from multivitamin and mineral supplements. These are readily available, inexpensive and generally regarded as safe." The multivitamin supplement used in the study focused on vitamins and minerals typically thought to help immunity. It contained 700 micrograms of vitamin A; 400 international units of vitamin D; 45 milligrams of vitamin E; 6.6 milligrams of vitamin B6; 400 micrograms of folate; 9.6 micrograms of vitamin B12; 1,000 milligrams of vitamin C; 5 milligrams of iron; 0.9 milligrams of copper; 10 milligrams of zinc; and 110 micrograms of selenium. "Supplementation was associated with significantly increased circulating levels of zinc and vitamin C, and with illness symptoms that were less severe and shorter lasting," Gombart said. "This supports findings that stretch back decades, even to the days of Linus Pauling's work with vitamin C. Our results suggest more and better designed research studies are needed to explore the positive role multivitamin and mineral supplementation might play in bolstering the immune system of older adults."     Honey found to be a better treatment for upper respiratory tract infections than traditional remedies Oxford University, August 19, 2020 A trio of researchers at Oxford University has found that honey is a better treatment for upper respiratory tract infections (URTIs) than traditional remedies. In their paper published in BMJ Evidence-based Medicine, Hibatullah Abuelgasim, Charlotte Albury, and Joseph Lee describe their study of the results of multiple clinical trials that involved testing of treatments for upper respiratory tract infections (URTIs) and what they learned from the data. Over the past several years, the medical community has grown alarmed as bacteria have developed resistance to antibacterial agents. Some studies have found that over-prescription of such remedies is hastening the pace. Of particular concern are antibacterial prescriptions written for maladies that they are not likely to help, simply due to demands from patients. One such case is often URTIs, the vast majority of which are caused by viruses, not bacteria. Because of such cases, scientists have been looking for other remedies for these infections, and one therapy in particular has begun to stand out: honey. Anecdotal evidence has suggested that honey can be used to treat colds in general and coughs in particular—people have been using it as a therapy for thousands of years. In this new effort, the researchers looked at the results of multiple clinical trials testing the effectiveness of therapies against URTIs. In all, the team looked at data from 14 clinical trials involving 1,761 patients. In analyzing the data from all of the trials combined, the researchers found that the trials had included studies of virtually all of the traditional remedies such as over-the-counter cold and sinus medicines as well as antibiotics—and honey. They found that honey proved to be the best therapy among all of those tested. In addition to proving more effective in treating coughing (36 percent better at reducing the amount of coughing and 44 percent better at reducing coughing severity), it also led to a reduction in average duration of infection by two days. The researchers note that the reason honey works as a treatment for URTIs is because it contains hydrogen peroxide—a known bacteria killer—which also makes it useful as a topical treatment for cuts and scrapes. Honey is also of the right consistency—its thickness works to coat the mouth and throat, soothing irritation.   High intensity physical activity in early life could lead to stronger bones in adulthood University of Bristol (UK), August 17 2020   The research, which analysed data from 2,569 participants of the Children of the 90s health study, found that more time spent doing moderate-to-vigorous intensity physical activity (MVPA) from age 12 years was associated with stronger hips at age 25 years, whereas time spent in light intensity activity was less clearly associated with adult hip strength. Peak bone mass occurs in young adulthood and is considered to be a marker of the risk of fracture and osteoporosis in later life. Hip fractures make up a large proportion of the osteoporosis disease burden.  Researchers looked at data from healthy individuals who had physical activity measured up to 4 times using accelerometers worn as part of clinical assessments at age 12, 14, 16 and 25 years. This is a device that measures a person's movement for the whole time they wear it. Researchers also found evidence to suggest that adolescent MVPA was more important than MVPA in adulthood, and that MVPA in early adolescence may be more important than in later adolescence. There was also some evidence that higher impact activity (consistent with jumping; assessed once in a subsample in late adolescence using custom accelerometer) was related to stronger hips at age 25. Dr Ahmed Elhakeem, lead author and Senior Research Associate in Epidemiology, said: "The unique availability of repeated accelerometer assessments over many years beginning at age 12 within the Children of the 90s cohort, allowed us to describe the trajectory of time spent in different physical activity intensities through early life and to examine how this might relate to adult hip strength. The results highlight adolescence as a potentially important period for bone development through high intensity exercise, which could benefit future bone health and prevent osteoporosis in later life. We have also confirmed other studies showing that levels of MVPA decline through adolescence. Our findings show it is really important to support young people to remain active at this age"  Francesca Thompson, Clinical and Operations Director at the Royal Osteoporosis Society (ROS), said: "The ROS is working closely at the moment with Public Health England to review the importance of exercise for bone health in children. The findings from this study are welcome as they provide further evidence that children need to be doing moderate to vigorous intensity physical activity during their early adolescence to maximise bone strength in later life and reduce the risk of painful fractures. Supporting and encouraging young people to be more physically active needs to be a priority for bone as well as general health."   Magnesium supplementation associated with improved vitamin D status in postmenopausal women University of Granada (Spain), August 17, 2020   According to news originating from Granada, Spain,  the research stated, “Menopause is a stage of hormonal imbalance in women which, in addition to other physiopathological consequences, poses a risk of deficiency of key micronutrients such as magnesium and vitamin D.” Our news editors obtained a quote from the research from University of Granada: “A study was made of the influence of a magnesium intervention upon vitamin D status in a postmenopausal population from the province of Granada (Spain). Fifty-two healthy postmenopausal women between 44-76 years of age were included. Two randomized groups-placebo and magnesium (500 mg/day)-were treated during eight weeks. Nutrient intake was assessed using questionnaires based on 72-h recall. Vitamin D was analyzed by liquid chromatography-tandem mass spectrometry. Baseline vitamin D proved deficient in over 80% of the subjects.” According to the news editors, the research concluded: “The administration of magnesium resulted in significantly increased vitamin D levels in the intervention group versus the controls (* * p* * < 0.05). Magnesium supplementation improved vitamin D status in the studied postmenopausal women.”     High fructose diet in pregnancy impacts metabolism of offspring, study finds University of Otago (New Zealand), August 18, 2020   An increased level of fructose intake during pregnancy can cause significant changes in maternal metabolic function and milk composition and alter the metabolism of their offspring, researchers from the University of Otago, Wellington, have found. The research, which was led by Dr Clint Gray, a Research Fellow in the Department of Paediatrics and Child Health, found increasing the fructose in the diets of female guinea pigs led to highly significant and consistent changes in the free fatty acids circulating in the blood of their offspring. This was despite the offspring consuming no fructose themselves.  The research is published in the international journal Frontiers in Endocrinology.  First author, PhD student Erin Smith, says "previous research has shown poor quality nutrition during pregnancy can predispose offspring to long-term consequences, including the development of obesity, diabetes and cardiovascular disease later in life".  "However, there has been a lack of data examining the impact of increased fructose intake before and during pregnancy and subsequent adverse effects on lactation, foetal development and offspring metabolic function." The two experimental groups were fed either a control diet or a fructose diet prior to and during pregnancy. The fructose group was given supplementary fructose water to replicate increased sugar-sweetened beverage intake 60 days prior to mating and until the delivery of their offspring. Fructose made up 16.5 per cent of their diets, closely resembling the average human consumption of fructose/sugar in Western countries, which is estimated at about 14 per cent of average daily caloric intake.  "We found fructose had a significant impact on a pregnant females' metabolic status and the free fatty acid content of their milk. We also provide the first evidence that offspring born from fructose-fed mothers display a very specific pattern of increased free fatty acids and altered lipid metabolism that persists throughout early life." Ms Smith says it is well known that increased levels of circulating free fatty acids increases the risk of obesity, insulin resistance, type 2 diabetes and cardiovascular disease - with increased fatty acid synthesis shown to occur following fructose consumption. She says the evidence suggests suboptimal maternal diets, such as diets high in fructose and refined sugars, may be contributing to the rise in metabolic diseases in humans observed during the past 40 to 50 years. "Our study emphasises the importance of limiting added refined fructose, such as sugar-sweetened beverages, and striving for a more nutritionally balanced diet in women prior to and during pregnancy and lactation."       Sleep makes relearning faster and longer-lasting University of Lyon (France). August 14, 2020   Getting some sleep in between study sessions may make it easier to recall what you studied and relearn what you've forgotten, even 6 months later, according to new findings from Psychological Science, a journal of the Association for Psychological Science.   "Our results suggest that interleaving sleep between practice sessions leads to a twofold advantage, reducing the time spent relearning and ensuring a much better long-term retention than practice alone," explains psychological scientist Stephanie Mazza of the University of Lyon. "Previous research suggested that sleeping after learning is definitely a good strategy, but now we show that sleeping between two learning sessions greatly improves such a strategy."   While studies have shown that both repeated practice and sleep can help improve memory, there is little research investigating how repetition and sleep influence memory when they are combined. Mazza and colleagues hypothesized that sleeping in between study sessions might make the relearning process more efficient, reducing the effort needed to commit information to memory.   A total of 40 French adults were randomly assigned to either a "sleep" group or a "wake" group. At the first session, all participants were presented with 16 French-Swahili word pairs in random order. After studying a pair for 7 seconds, the Swahili word appeared and participants were prompted to type the French translation. The correct word pair was then shown for 4 seconds. Any words that were not correctly translated were presented again, until each word pair had been correctly translated.   Twelve hours after the initial session, the participants completed the recall task again, practicing the whole list of words until all 16 words were correctly translated.   Importantly, some participants completed the first session in the morning and the second session in the evening of the same day ("wake" group); others completed the first session in the evening, slept, and completed the second session the following morning ("sleep" group).   In the first session, the two groups showed no difference in how many words they could initially recall or in the number of trials they needed to be able to remember all 16 word pairs.   But after 12 hours, the data told another story: Participants who had slept between sessions recalled about 10 of the 16 words, on average, while those who hadn't slept recalled only about 7.5 words. And when it came to relearning, those who had slept needed only about 3 trials to be able to recall all 16 words, while those who had stayed awake needed about 6 trials.   Ultimately, both groups were able to learn all 16 word pairs, but sleeping in between sessions seemed to allow participants to do so in less time and with less effort.   "Memories that were not explicitly accessible at the beginning of relearning appeared to have been transformed by sleep in some way," says Mazza. "Such transformation allowed subjects to re-encode information faster and to save time during the relearning session."   The memory boost that participants got from sleeping between sessions seemed to last over time. Follow-up data showed that participants in the sleep group outperformed their peers on the recall test 1 week later. The sleep group showed very little forgetting, recalling about 15 word pairs, compared to the wake group, who were able to recall about 11 word pairs. This benefit was still noticeable 6 months later.   The benefits of sleep could not be ascribed to participants' sleep quality or sleepiness, or to their short-term or long-term memory capacity, as the two groups showed no differences on these measures.   The results suggest that alternating study sessions with sleep might be an easy and effective way to remember information over longer periods of time with less study, Mazza and colleagues conclude.       Meta-analysis adds evidence to chromium supplementation's glucose control benefits in diabetics Lorestan University of Medical Sciences (Iran), August 15, 2020   A systematic review and meta-analysis published on July 27, 2020 in Pharmacological Research found reductions in fasting plasma glucose, insulin, hemoglobin A1c (HbA1c, a marker of long term glucose control) and insulin resistance in men and women with type 2 diabetes who supplemented with the mineral chromium.  For their analysis, Omid Asbaghi of Lorestan University of Medical Sciences and colleagues selected 23 randomized, controlled trials that evaluated the effects of supplementing with chromium on various glycemic control indexes. Doses used in the studies ranged between 50 micrograms (mcg) and 1,000 mcg per day consumed from four to 25 weeks. Eleven of the trials evaluated a chromium dosage within a 400 to 600 mcg range.  Analysis of 22 trials that reported fasting plasma glucose levels concluded that chromium supplementation was associated with an average reduction of 19.0 milligrams per deciliter (mg/dL) in comparison with the placebo. Trials of at least 12 weeks duration were associated with a far greater average decrease of 58.74 mg/dL in association with chromium.  Of the 14 trials that reported insulin levels, levels declined by an average of 1.7784 µIU/mL among subjects who received chromium compared to the placebo, with trials that lasted 12 weeks or longer associated with a decrease of 3.47 µIU/mL.  For the 22 trials that reported HbA1c, supplementation with chromium was associated with an average decrease of 0.71%, which improved to a significant 1.70% reduction when trials of 12 weeks duration or more were examined. Homeostatic model assessment for insulin resistance (HOMA-IR) also decreased significantly among participants who received chromium.  The authors observed that chromium plays a role in carbohydrate and lipid metabolism and may enhance insulin sensitivity. Other nutrients that have been associated with a lower risk of type 2 diabetes include vitamins A, C, D and E, beta-carotene, calcium, magnesium, potassium and zinc. “Present systematic review and meta-analysis of all available published randomized trials up to 2020 found a significant reduction in all glycemic control indices such as fasting plasma glucose, insulin, HbA1c and HOMA-IR levels after chromium supplementation,” they wrote. “Furthermore, long term intervention contributed to greater reduction of all mentioned indices.” “The results of the current meta‐analysis study might support the use of chromium supplementation for the improvement of glycemic control indices in T2DM patients,” they concluded.       Mangiferin: The Health-Boosting Antioxidant in Mangos GreenMedInfo, August 12th 2020    Mangiferin, a polyphenol found in mango fruit and plant extracts, possesses potent antioxidant and anti-inflammatory properties. Mangiferin has been shown to have beneficial effects on gastrointestinal health, Type 2 diabetes and cardiovascular health, and may have anticancer properties Mango, a type of juicy stone fruit native to eastern Asia and India, is rich in omega-3 and omega-6 fatty acids, fiber, antioxidants, micronutrients and minerals, and a unique polyphenol called mangiferin.[i] While mango itself has long been touted for its health benefits, researchers are becoming increasingly interested in mangiferin, which can be found in the leaves, fruit, stone, kernel and stems of the mango plant.[ii] Studies show that mangiferin extracts may have beneficial effects on lifestyle-related disorders and degenerative diseases, and researchers are eager to understand and utilize this potent polyphenol. Antioxidant and Anti-Inflammatory Potential of Mangiferin Mangiferin is a powerful antioxidant that modulates glucose metabolism and shows enhanced antioxidant capabilities in both inflammatory and pro-inflammatory conditions.[iii] Mangiferin antioxidants have also been shown to protect against liver damage and lower peroxidation in human peripheral blood lymphocytes, and mangiferin may have radioprotective properties thanks to its ability to suppress free radicals in cells.[iv],[v] Additionally, mangiferin's anti-inflammatory benefits have been demonstrated in both the liver and heart, and researchers have discovered that mangiferin can protect against lipid peroxidation and oxidative stress by up-regulating the expression of Nrf2, a transcription factor responsible for the regulation of protective antioxidants and detoxification responses.[vi],[vii] Mangiferin's anti-inflammatory effects have also been demonstrated in the lungs, where it can improve acute lung injury by reducing systemic and pulmonary inflammationresponses.[viii] Overall, mangiferin's anti-inflammatory properties have been demonstrated to reduce both macro and microscopic damage in various organs and tissues, making it a potential preventative therapy for a variety of disorders.[ix] Many of the benefits of mangiferin come from these strong antioxidant and anti-inflammatory properties. Researched benefits of mangiferin include: Mangiferin Extract May Protect Against Diabetes More than 80% of all diabetes cases are Type 2, which is associated with a lowered ability to increase glucose utilization in skeletal muscle tissue and adipose tissue.[x] This decrease in glucose metabolism and increased insulin increases the risk for disorders like cardiovascular disease, fatty liver and renal diseases.[xi] In one study, researchers demonstrated that mangiferin extract significantly reduced kidney weight while enhancing enzymatic activity and protein expression after just nine weeks.[xii] Other studies have shown that mangiferin extract can also reduce low-density lipoprotein (LDL) cholesterol and improve oral-glucose tolerance after just 28 days.[xiii] Mangiferin Boosts Gastrointestinal Health Mangiferin has gastroprotective effects, leading researchers to believe it could be a useful therapeutic measure against gastric complications including diarrhea, abdominal pain, weight loss and anemia associated with Crohn's disease and ulcerative colitis.[xiv] These effects are likely due to mangiferin's antioxidant and anti-inflammatory properties, which both contribute to the development of gastrointestinal disorders.[xv] In other studies, researchers have found that mangiferin improves postoperative ileus, a short-term disturbance of gastrointestinal motility after surgery.[xvi] Mangiferin improves intestinal transit by reducing the intestinal inflammatory response and decreasing pro-inflammatory cytokine levels in the plasma, improving gastrointestinal transit in both normal and constipated subjects.[xvii],[xviii] Mangiferin Has Anticancer Properties Researchers believe that one root cause of carcinogenesis is oxidative stress and have long searched for natural, polyphenolic antioxidant compounds that could mediate oxidative damage in the body. One study found that mangiferin's antioxidant capabilities may stall the progression of carcinogenesis and induce apoptosis (cell death) on cancer cells.[xix] Mangiferin is demonstrated to have protective effects against several cancers, including breast, colon, neural, skin and cervical cancers, by lowering oxidative stress and suppressing DNA damage in cells in various studies.[xx] Mangiferin Has Immunomodulatory Properties Mangiferin's strong immunomodulatory characteristics come from its ability to both reduce oxidative stress in lymphocytes, neutrophils and macrophages, and also enhance the number and activity of immune cells in your body.[xxi],[xxii] Additionally, mangiferin inhibits lipid peroxidation, which researchers believe may account for the reduction of radiation-induced DNA damage to immune cells and explain mangiferin's strong immune-stimulating and anticancer effects.[xxiii] Mangiferin Protects Against Cardiovascular Disease Mangiferin may play a significant cardiovascular-protective role by decreasing fatty acids, cholesterol and triglycerides and decreasing the inflammatory process in heart tissue.[xxiv] Mangiferin treatment is also shown to increase enzymatic activity and reduce the formation of lipid peroxides, which researchers use as a marker for cardiovascular disease risk and vascular cognitive impairment disorders.[xxv] Given that mangiferin exhibits little to no toxicity and has anti-inflammatory and antioxidant benefits, there is strong evidence that mangiferin can be used as an alternative or preventive therapy against a variety of illnesses.[xxvi] However, it has a low water solubility and oral bioavailability and researchers must find an effective dosage and enhance its absorption rate before it can effectively be used in clinical settings.  

Where to Find Credible InformationKaren Daw is an award-winning national speaker, author of numerous articles and CE courses on safety in dentistry. Furthermore she is a consultant for Finding Credible Information for practices across the country. She earned her BA from the Ohio State University and her MBA with concentrations in Healthcare Administration and Business Management.After graduating, Karen was recruited from the Emergency Department to her roles as Assistant Director of Sterilization Monitoring and Health and Safety Director for the OSU College of Dentistry. Karen draws on her rich background to educate audiences large and small on building a culture of safety.Want to learn more about Karen Daw Consulting & Finding Credible Information?Visit: KarenDaw.comTo Find and Listen to all of The Dental Brief EpisodesVisit:  dentalbrief.comOur Sponsor:OmniPremier.com

Lipoic acid supplements help some obese but otherwise healthy people lose weight Oregon State University, August 12, 2020   A compound given as a dietary supplement to overweight but otherwise healthy people in a clinical trial caused many of the patients to slim down, research by Oregon State University and Oregon Health & Science University showed.  The research, published in the Journal of Nutrition, analyzed the effects of 24 weeks of daily, 600-milligram doses of lipoic acid supplements on 31 people, with a similarly sized control group receiving a placebo. "The data clearly showed a loss in body weight and body fat in people taking lipoic acid supplements," said Balz Frei, director emeritus of OSU's Linus Pauling Institute and one of the scientists on the study. "Particularly in women and in the heaviest participants." Produced by both plants and animals, lipoic acid sets up shop in cells' mitochondria, where it's normally attached to proteins involved in energy and amino acid metabolism. A specialized, medium-chain fatty acid, it's unique in having two sulfur atoms at one end of the chain, allowing for the transfer of electrons from other sources. The body generally produces enough lipoic acid to supply the enzymes whose proper function requires it. When taken as a dietary supplement, lipoic acid displays additional properties that might be unrelated to the function in the mitochondria. They include the stimulation of glucose metabolism, antioxidant defenses and anti-inflammatory responses - making it a possible complementary treatment for people with diabetes, heart disease and age-related cognitive decline. "Scientists have been researching the potential health benefits of lipoic acid supplements for decades, including how it might enhance healthy aging and mitigate cardiovascular disease," said Alexander Michels, another Linus Pauling Institute scientist involved with the study. "In both rodent models and small-scale human clinical trials, researchers at the LPI have demonstrated the beneficial effects of lipoic acid on oxidative stress, lipid metabolism and circadian rhythm." The OSU/OHSU project addressed two issues commonly ignored by previous human trials, said Tory Hagen, a professor of biochemistry and biophysics in the OSU College of Science and the study's corresponding author. "Many existing clinical studies using lipoic acid have focused on volunteers with pre-existing conditions like diabetes, making it difficult to determine if lipoic acid supplements simply act as a disease treatment or have other beneficial health effects," said Hagen, principal investigator and Helen P. Rumbel Professor for Healthy Aging Research at the institute. "Another issue is the formulation of the supplement. Many previous studies have used the S form of lipoic acid, which is a product of industrial synthesis and not found in nature. We only used the R form of lipoic acid - the form found in the body naturally." Contrary to what was expected by the researchers, decreased levels of triglycerides - a type of fat, or lipid, found in the blood - were not seen in all the participants taking lipoic acid.  "The effect of lipoic acid supplements on blood lipids was limited," said Gerd Bobe, another LPI scientist who collaborated on the study. "But people who lost weight on lipoic acid also reduced their blood triglyceride levels - that effect was clear."  Other effects of the lipoic acid supplements were measurable as well. "By the end of the study, some markers of inflammation declined," Hagen said. "The findings also suggest that lipoic acid supplementation provides a mild reduction in oxidative stress. It is not a perfect panacea, but our results show that lipoic acid supplements can be beneficial." Identifying which patients will benefit the most from lipoic acid supplementation, and how much they need, is important for both clinical and economic reasons, he added. "Lipoic acid supplements are often quite expensive," he said. "So understanding how we can maximize benefits with smaller amounts of the supplement is something we are interested in pursuing."   Meditation-relaxation therapy may offer escape from the terror of sleep paralysis Cambridge University, August 12, 2020   Sleep paralysis - a condition thought to explain a number of mysterious experiences including alleged cases of alien abduction and demonic night-time visits - could be treated using a technique of meditation-relaxation, suggests a pilot study published today. Sleep paralysis is a state involving paralysis of the skeletal muscles that occurs at the onset of sleep or just before waking. While temporarily immobilised, the individual is acutely aware of their surroundings. People who experience the phenomenon often report being terrorised by dangerous bedroom intruders, often reaching for supernatural explanations such as ghosts, demons and even alien abduction. Unsurprisingly, it can be a terrifying experience. As many as one in five people experiences sleep paralysis, which may be triggered by sleep deprivation, and is more frequent in psychiatric conditions like post-traumatic stress disorder. It is also common in narcolepsy, a sleep disorder involving excessive daytime sleepiness and sudden loss of muscle control.  Despite the condition being known about for some time, to date there are no empirically-based treatments or published clinical trials for the condition.  Today, in the journal Frontiers in Neurology, a team of researchers report a pilot study of meditation-relaxation therapy involving 10 patients with narcolepsy, all of whom experience sleep paralysis. The therapy was originally developed by Dr Baland Jalal from the Department of Psychiatry, University of Cambridge. The current study was led by Dr Jalal and conducted in collaboration with Dr Giuseppe Plazzi's group at the Department of Biomedical and Neuromotor Sciences, University of Bologna/IRCCS Istituto delle Scienze Neurologiche di Bologna, Italy. The therapy teaches patients to follow four steps during an episode:   1. Reappraisal of the meaning of the attack - reminding themselves that the experience is common, benign, and temporary, and that the hallucinations are a typical by-product of dreaming 2. Psychological and emotional distancing - reminding themselves that there is no reason to be afraid or worried and that fear and worry will only make the episode worse  3. Inward focused-attention meditation - focusing their attention inward on an emotionally-involving, positive object (such as a memory of a loved one or event, a hymn/prayer, God) 4. Muscle relaxation - relaxing their muscles, avoiding controlling their breathing and under no circumstances attempting to move   Participants were instructed to keep a daily journal for four weeks to assess sleep paralysis occurrence, duration and emotions. Overall, among the 10 patients, two-thirds of cases (66%) reported hallucinations, often upon awakening from sleep (51%), and less frequently upon falling asleep (14%) as rated during the first four weeks. After the four weeks, six participants completed mood/anxiety questionnaires and were taught the therapy techniques and instructed to rehearse these during ordinary wakefulness, twice a week for 15 min. The treatment lasted eight weeks.  In the first four weeks of the study, participants in the meditation-relaxation group experienced sleep paralysis on average 14 times over 11 days. The reported disturbance caused by their sleep paralysis hallucinations was 7.3 (rated on a ten-point scale with higher scores indicating greater severity).  In the final month of the therapy, the number of days with sleep paralysis fell to 5.5 (down 50%) and the total number of episodes fell to 6.5 (down 54%). There was also a notable tendency towards reductions in the disturbance caused by hallucinations with ratings dropping from 7.3 to 4.8. A control group of four participants followed the same procedure, except participants engaged in deep breathing instead of the therapy - taking slow deep breaths, while repeatedly counting from one to ten.  In the control group, the number of days with sleep paralysis (4.3 per month at the start) was unchanged, as well as their total number of episodes (4.5 per month initially). The disturbance caused by hallucinations was likewise unchanged (rated 4 during the first four weeks). "Although our study only involved a small number of patients, we can be cautiously optimistic of its success," said Dr Jalal. "Meditation-relaxation therapy led to a dramatic fall in the number of times patients experienced sleep paralysis, and when they did, they tended to find the notoriously terrorising hallucinations less disturbing. Experiencing less of something as disturbing as sleep paralysis is a step in the right direction." If the researchers are able to replicate their findings in a larger number of people - including those from the general population, not affected by narcolepsy - then this could offer a relatively simple treatment that could be delivered online or via a smartphone to help patients cope with the condition. "I know first-hand how terrifying sleep paralysis can be, having experienced it many times myself," said Dr Jalal. "But for some people, the fear that it can instil in them can be extremely unpleasant, and going to bed, which should be a relaxing experience, can become fraught with terror. This is what motivated me to devise this intervention."   Why walking to work may be better for you than a casual stroll Study finds people walk faster, report being healthier, when they walk with a purpose Ohio State University, August 12, 2020   Walking with a purpose - especially walking to get to work - makes people walk faster and consider themselves to be healthier, a new study has found.  The study, published online earlier this month in the Journal of Transport and Health, found that walking for different reasons yielded different levels of self-rated health. People who walked primarily to places like work and the grocery store from their homes, for example, reported better health than people who walked mostly for leisure. "We found that walking for utilitarian purposes significantly improves your health, and that those types of walking trips are easier to bring into your daily routine," said Gulsah Akar, an associate professor of city and regional planning in The Ohio State University Knowlton School of Architecture. "So, basically, both as city planners and as people, we should try to take the advantage of this as much as possible." The study used data from the 2017 National Household Travel Survey, a U.S. dataset collected from April 2016 to May 2017.  The researchers analyzed self-reported health assessments from 125,885 adults between the ages of 18 and 64. Those adults reported the number of minutes they spent walking for different purposes - from home to work, from home to shopping, from home to recreation activities and walking trips that did not start at their homes.  And, the survey respondents ranked how healthy they were on a scale of 1 to 5. The dataset the researchers analyzed included more than 500,000 trips. The researchers - Akar and Ohio State doctoral student Gilsu Pae - found that walking for any duration, for any purpose, increased how healthy a person felt.  But they also found that an additional 10 minutes of walking per trip from home for work-based trips - say, from a person's house to the bus stop 10 minutes away - increased that person's odds of having a higher health score by 6 percent compared with people who walk for other reasons. People who walked from home for reasons not connected to work, shopping or recreation were 3 percent more likely to have a higher health score. And, the researchers found, people who walked for work walked faster - on average, about 2.7 miles per hour - than people who walked for other reasons. People who walked for recreational purposes - say, an after-dinner stroll - walked, on average, about 2.55 miles per hour.  The researchers also found that walking trips that begin at home are generally longer than walking trips that begin somewhere else. The team found that 64 percent of home-based walking trips last at least 10 minutes, while 50 percent of trips that begin elsewhere are at least that long. Akar has studied the ways people travel for years, and said she was surprised to see that walking for different purposes led to a difference in how healthy people believed they were. "I was thinking the differences would not be that significant, that walking is walking, and all forms of walking are helpful," she said. "And that is true, but walking for some purposes has significantly greater effect on our health than others." Akar said the findings suggest that building activity into parts of a day that are otherwise sedentary - commuting by foot instead of by car, for example - can make a person feel healthier. "That means going to a gym or a recreation center aren't the only ways to exercise," Akar said. "It's an opportunity to put active minutes into our daily schedules in an easy way."   Eating raw organic fruits and veggies helps boost your gut health Graz University of Technology (Austria), August 12, 2020    A study published in the journal Frontiers in Microbiology found that consuming organic produce promotes gut microbiome diversity. Birgit Wassermann, the first author of the study and a researcher at the Graz University of Technology in Austria, explained that consuming raw fruits and vegetables is key to maintaining a diverse microbial community, which is essential for a healthy gut microbiome and a strong immune system. But these foods don't need to just be raw, they should also be organically produced. In their study, Wassermann and her colleagues found that while the production method didn't affect the abundance of microbes found in the different tissues of apples, the microbes present in organically produced apples were more diverse than those harbored by conventionally produced ones. Wassermann and her team chose to study apples because they are popular worldwide. In 2018 alone, about 83 million apples were grown, and production continues to grow today. Organic vs conventional Using genetic analysis and fluorescence microscopy, the researchers found that both conventional apples and organic apples had roughly the same amount of total bacteria (about 100 million per apple). While different parts of the fruit contained distinct microbial communities, apple pulp and seeds had the largest bacterial colonies. Apple peels were surprisingly less colonized. The researchers also found that organic apples had a more diverse bacterial population than conventionally grown apples. Additionally, organic apples contained beneficial bacteria, such as the common probiotic, Lactobacillus. On the other hand, conventional apples had a greater chance of containing potentially pathogenic bacteria like Escherichia and Shigella, both of which are linked to food poisoning symptoms like cramps and diarrhea. According to Wassermann, the very diverse microbiome of organically grown apples can help fight human pathogens by outcompeting them. She explained that the microbial pool that organic apple trees are exposed to tends to be more diverse and more balanced, and this helps promote their health by bolstering their resistance to pathogens. (Related: Exploring the ”gut-heart” connection: Can heart failure be treated by boosting gut microbiota health?) The difference between “organic” and “conventional” fruits According to the United States Department of Agriculture (USDA), organic is a label for foods that are grown in accordance with certain federal guidelines. These guidelines include factors like soil additives, pesticide use and how animals are raised. On the other hand, conventional refers to modern, industrial agriculture that uses chemical fertilizers, pesticides and genetically modified organisms (GMOs). Research suggests that organic produce has a similar nutritional profile to conventional produce, but the former helps reduce your exposure to pesticides and harmful bacteria. When buying produce, consider other health factors like chronic conditions or pregnancy. To narrow down your search, start by learning about the fruits and vegetables that are more likely to be exposed to different kinds of pesticides.     Smiling can trick your mind into being more positive, study finds University of South Australia, August 11, 2020   From Sinatra to Katy Perry, celebrities have long sung about the power of a smile—how it picks you up, changes your outlook, and generally makes you feel better. But is it all smoke and mirrors, or is there a scientific backing to the claim? Groundbreaking research from the University of South Australia confirms that the act of smiling can trick your mind into being more positive, simply by moving your facial muscles. With the world in crisis amid COVID-19, and alarming rises of anxiety and depression in Australia and around the world, the findings could not be more timely. The study, published in Experimental Psychology, evaluated the impact of a covert smile on perception of face and body expressions. In both scenarios, a smile was induced by participants holding a pen between their teeth, forcing their facial muscles to replicate the movement of a smile. The research found that facial muscular activity not only alters the recognition of facial expressions but also body expressions, with both generating more positive emotions. Lead researcher and human and artificial cognition expert, UniSA's Dr. Fernando Marmolejo-Ramos says the finding has important insights for mental health. "When your muscles say you're happy, you're more likely to see the world around you in a positive way," Dr. Marmolejo-Ramos says. "In our research we found that when you forcefully practice smiling, it stimulates the amygdala—the emotional center of the brain—which releases neurotransmitters to encourage an emotionally positive state. For mental health, this has interesting implications. If we can trick the brain into perceiving stimuli as 'happy', then we can potentially use this mechanism to help boost mental health." The study replicated findings from the "covert" smile experiment by evaluating how people interpret a range of facial expressions (spanning frowns to smiles) using the pen-in-teeth mechanism; it then extended this using point-light motion images (spanning sad walking videos to happy walking videos) as the visual stimuli. Dr. Marmolejo-Ramos says there is a strong link between action and perception. "In a nutshell, perceptual and motor systems are intertwined when we emotionally process stimuli," Dr. Marmolejo-Ramos says. "A 'fake it 'til you make it' approach could have more credit than we expect."   Coriander is a potent weapon against antibiotic resistant bacteria University of Beira Interior (Portugal) August 10, 2020         The problem of antibiotic resistant bacteria has been deemed a public health crisis, with the Centers for Disease Control and Prevention (CDC) reporting that invasive MRSA – or methicillin-resistant S. aureus – infections affect 80,000 people globally a year, and claim over 11,000 lives. But, what the CDC will never tell you is how coriander can potentially save lives. Researchers in Portugal now say that that the oil from coriander – a common kitchen spice – is quite toxic to a wide range of harmful bacteria, leading to hopes that it may be enlisted in the fight against MRSA and other pathogens. Researchers at University of Beira Interior used flow cytometry to study the effects of coriander oil on 12 different disease-causing types of bacteria, including E. coli, Salmonella, B. cereus and MRSA. In the study, published in Journal of Medical Microbiology, the oil significantly inhibited bacterial growth – especially that of MRSA and E. coli. Researchers found that the coriander oil worked by damaging the membrane around the bacterial cell, interfering with vital functions such as respiration and eventually causing cell death. Linalool, a terpenoid responsible for coriander's pleasant scent, is the main constituent, but the coriander oil outperformed linalool alone – showing that interactions between the components in coriander oil made it even more bactericidal. Finally, the team found that coriander tended to perform better on Gram-negative bacteria such as E. coli and salmonella – as it could more easily disrupt their cell membranes. Lead researcher Dr. Fernanda Domingues noted that using coriander in foods could help prevent bacterial spoilage and food-borne illnesses, and possibly function as a natural alternative to pharmaceutical antibiotics. The team called for further study to explore practical applications and delivery systems. Coriander, scientifically known as Coriandrum sativum L. and also called cilantro and Chinese parsley, is an herb used in Mediterranean, Asian, Indian and Mexican cuisine, where it lends its spicy, bracing flavor to chutneys, pickles, sauces and salads. A staple of folk and herbal medicine, coriander has pain-relieving, antioxidant, anti-inflammatory and antimicrobial effects. The seeds have even been used for their mild relaxant, anxiety-easing and mood-elevating properties, and the diluted essential oil has been used to treat topical skin infections. For this study, researchers used essential oil of coriander, but other research on coriander's antimicrobial qualities has used other forms, such as freeze-dried powder. Coriander essential oil is one of the most widely-used in the world, and is already in use as a food additive. The need to develop safe, non-chemical preservatives – and the need to find natural solutions for antibiotic resistant bacteria – mean that studies on natural, herbal substances such as coriander are a “research hotspot.” Coriander has impressed researchers with its antimicrobial properties, and additional studies attest to that fact. In a study published in International Journal of Food Nutrition and Safety, researchers found that a water extract of coriander had a very strong inhibitory effect on E. coli and B.subtilis. Many serotypes of E.coli can cause illness, and B. subtilis, while not a disease-causing pathogen, can contaminate food, and cause potatoes to rot. Researchers found that the coriander extract worked best to inhibit bacteria when it was prepared in a concentration of 10 percent, with a pH of 6 and a salt concentration of 2 percent. And, a 2015 study published in Critical Reviews in Food Science and Nutrition showed that coriander seed oil exhibited antimicrobial activity against both Gram-positive and Gram-negative bacteria – along with some yeasts and fungi. Researchers expressed their belief in the successful development of a food preservation strategy featuring coriander oil. MRSA continues to threaten lives, while food-borne illnesses affect up to 30 percent of the population of developed countries – yearly. The CDC reports that a type of infection called STEC – Shiga toxin-producing E. coli – strikes a whopping 265,000 people every year in the United States alone, causing symptoms of severe stomach cramps, vomiting and diarrhea. And, finally, coriander seed oil – non-toxic, non-chemical, and packed with beneficial flavonoids – may very well be the food preservative and antibacterial agent of the future.     Exercise can improve mental health McGill University (Quebec), August 10, ,2020 One in four men in the world suffer from mental health issues. More men than women die from mental health issues. Dr. Farhan Khawajawho holds a Ph.D in Neuroscience from Mcgill University has said that regular fitness routines can help reduce the number of people whosuffer from long term mental health issues and can save lives. Dr. Farhan Khawaja has launched a campaign to make men aware of how important regular fitness is to their mental health and well-being. The fitness experts have said regular exercise can help deal with stress and reduce mental health problems. According to a recent report, more than 450 million people in the world suffer from mental health issues. In the UK more than 16 million people suffer from stress and mental health problems, in the USA that figure stands at 46.6 million. The World Health Organization has said that one in four men suffer from mental health problems and men are more likely than women to lose their life to this rising killer disease. Dr. Farah Khawaja who has called for more to be done to help men who suffer from stress and depression, and mental health problems want more men to turn to exercise to beat this rising problem. "Exercise and going to the gym and running in the park is not just about losing weight, it can also help with people's well-being. Regular fitness can be a very highly effective way of dealing with stress, anxiety, and depression. It is the perfect way to help a person to fight the negative feelings they have," explained Dr. Farhan Khawaja. In 2019, 6507 deaths were recorded due to suicide, in the USA 129 people take their own life due to mental health problems. Those figures show the importance of why more needs to be done according to Dr. Farhan Khawaja. It is not just Dr. Farhan Khawaja who has said that regular exercise can help fight depression, stress, and anxiety, scientists have also written many reports on the subject. They have said they have found through studies that exercise can reduce the levels of tension a person may feel and can help elevate and stabilize mood, improve sleep patterns, and improve a person's self-esteem. According to one scientist report, even five minutes of aerobic exercise can have a positive impact on someone suffering from anxiety and stress. "We want to see more people exercise. They don't have to join an expensive gym; they can do exercise in the home or at the park. Through regular exercise it can help boost a person's overall mood and well-being," explained Dr. Farhan Khawaja. Dr. Farhan Khawajabelieves that if more people spent just ten minutes a day exercising, it could help reduce the number of people who suffer from stress.     Study shows how food preservatives may disrupt human hormones and promote obesity Cedars-Sinai  Medicine Institute, August 9, 2020    Can chemicals that are added to breakfast cereals and other everyday products make you obese? Growing evidence from animal experiments suggests the answer may be "yes." But confirming these findings in humans has faced formidable obstacles - until now. A new study published today in Nature Communications details how Cedars-Sinai investigators developed a novel platform and protocol for testing the effects of chemicals known as endocrine disruptors on humans. The three chemicals tested in this study are abundant in modern life. Butylhydroxytoluene (BHT) is an antioxidant commonly added to breakfast cereals and other foods to protect nutrients and keep fats from turning rancid; perfluorooctanoic acid (PFOA) is a polymer found in some cookware, carpeting and other products; and tributyltin (TBT) is a compound in paints that can make its way into water and accumulate in seafood. The investigators used hormone-producing tissues grown from human stem cells to demonstrate how chronic exposure to these chemicals can interfere with signals sent from the digestive system to the brain that let people know when they are "full" during meals. When this signaling system breaks down, people often may continue eating, causing them to gain weight. "We discovered that each of these chemicals damaged hormones that communicate between the gut and the brain," said Dhruv Sareen, PhD, assistant professor of Biomedical Sciences and director of the Induced Pluripotent Stem Cell Core Facility at the Cedars-Sinai Board of Governors Regenerative Medicine Institute. "When we tested the three together, the combined stress was more robust." Of the three chemicals tested, BHT produced some of the strongest detrimental effects, Sareen said. While other scientists have shown these compounds can disrupt hormone systems in laboratory animals, the new study is the first to use human pluripotent stem cells and tissues to document how the compounds may disrupt hormones that are critical to gut-to-brain signaling and preventing obesity in people, Sareen said. "This is a landmark study that substantially improves our understanding of how endocrine disruptors may damage human hormonal systems and contribute to the obesity epidemic in the U.S.," said Clive Svendsen, PhD, director of the institute and the Kerry and Simone Vickar Family Foundation Distinguished Chair in Regenerative Medicine. More than one-third of U.S. adults are considered to be obese, according to federal statistics. The new testing system developed for the study has the potential to provide a much-needed, safe and cost-effective method that can be used to evaluate the health effects of thousands of existing and new chemicals in the environment, the investigators say. For their experiments, Sareen and his team first obtained blood samples from adults, and then, by introducing reprogramming genes, converted the cells into induced pluripotent stem cells. Then, using these stem cells, the investigators grew human epithelium tissue, which lines the gut, and neuronal tissues of the brain's hypothalamus region, which regulates appetite and metabolism. The investigators then exposed the tissues to BHT, PFOA and TBT, one by one and also in combination, and observed what happened inside the cells. They found that the chemicals disrupted networks that prepare signaling hormones to maintain their structure and be transported out of the cells, thus making them ineffective. The chemicals also damaged mitochondria - cellular structures that convert food and oxygen into energy and drive the body's metabolism. Because the chemical damage occurred in early-stage "young" cells, the findings suggest that a defective hormone system potentially could impact a pregnant mother as well as her fetus in the womb, Sareen said. While other scientists have found, in animal studies, that effects of endocrine disruptors can be passed down to future generations, this process has not been proved to occur in humans, he explained. More than 80,000 chemicals are registered for use in the U.S. in everyday items such as foods, personal care products, household cleaners and lawn-care products, according to the National Toxicology Program of the U.S. Department of Health and Human Services. While the program states on its website that relatively few chemicals are thought to pose a significant risk to human health, it also states: "We do not know the effects of many of these chemicals on our health." Cost and ethical issues, including the health risk of exposing human subjects to possibly harmful substances, are among the barriers to testing the safety of many chemicals. As a result, numerous widely used compounds remain unevaluated in humans for their health effects, especially to the hormone system. "By testing these chemicals on actual human tissues in the lab, we potentially could make these evaluations easier to conduct and more cost-effective," Sareen said.

Dan Skinner talks with Dean of the College of Nursing and Chief Wellness Officer at Ohio State University, Dr. Bernadette Melnyk; Chief Diversity Officer, Dr. Angela Alston; and Director of OSU's health clinic, Dr. Candy Rinehart. Topics include nurses during COVID-19, health disparities and what nurses are doing to reduce them, burnout and mental health challenges within the nursing workforce, considerations in reopening OSU's campus for the Fall 2020 semester, and more. Show notes up at wcbe.org under the Podcast Experience tab. Follow Prognosis Ohio on Twitter at @prognosisohio.

Even if you think you've heard it all before, you've never heard it the way Karen Daw, “The OSHA Lady,” delivers OSHA and Infection Control training. With a fresh, fun, and efficient approach, Karen keeps things moving, always grounded in real-world examples of what can go wrong (sometimes in a matter of seconds) if we let our guard down. Karen Daw is an award-winning national speaker, author of numerous articles and CE courses on safety in dentistry, and a consultant to practices across the country. She earned her BA from the Ohio State University and her MBA with concentrations in Healthcare Administration and Business Management. After graduation, Karen was recruited from the Emergency Department to her roles as Assistant Director of Sterilization Monitoring and Health and Safety Director for the OSU College of Dentistry. Karen draws on her rich background to educate audiences large and small on how NOT to do safety, and best practices to avoid penalties, negative reviews and the 6 o'clock news!     SHOW NOTES: Below are some things you can do to create a culture of safety for your practice: Schedule training for your team Test your water lines Conduct a sterilization audit Train your team on personnel protective equipment Train your team on the chemical hazards in the workplace For more information on Karen Daw, you can visit her website at www.theoshalady.com   DINO'S BIO: Dino Watt is a dynamic, highly sought after keynote speaker, private practice business advisor, best selling author, and certified body language and communication expert. As a business relationship expert, Dino understands that people are the heart of any business. His interactive training style will bring your audience to roaring laughter and move them to tears. Whether he is training on C.O.R.E Culture, Sales and Sales Support, or Making love and business work, your audience will rave about Dino and the energy he brings to every event. Dino has spoken for MKS, American Association of Orthodontists, PCSO, Pitts Progressive Study Group, The Shulman Study Club, Keller Williams, Sotheby's, DentalTown, Ortho2, OrthoVoice, and many others. Out of all the accolades Dino has received, the one he is proudest of is title of PHD, Passionate Husband and Dad. Dino has been married to his wife Shannon for 24 years and together they have raised 3 amazing adults.  

In part 3 of our interview with Dr. Michael Prats of the OSU College of Medicine, we ask him how he is inspired by the person of Jesus, and we ask him if he's ever felt that his faith has been misunderstood in the medical context.------Learn more about Dr. Prats at The Thompson Institute: https://thethompsoninstitute.org/about/faculty-fellows/michael-prats-medicine -For more reflection on the implications of Jesus' human limitations, check out Pete Scazzero's article:https://www.emotionallyhealthy.org/lessons-radical-leadership-jesus/?v=7516fd43adaa-----The Walk is a production of The Thompson Institute, a program of Cru at Ohio StateProduced by Aaron Badenhop & Jordan BrowningEdited by Seth Costello & Lukas MorelandMusic by Jordan BrowningSpecial thanks to Dr. Michael Prats

Karen Daw is an award-winning national speaker, author of numerous articles and CE courses on safety in dentistry, and a consultant to practices across the country. She earned her BA from the Ohio State University and her MBA with concentrations in Healthcare Administration and Business Management. After graduation, Karen was recruited from the Emergency Department to her roles as Assistant Director of Sterilization Monitoring and Health and Safety Director for the OSU College of Dentistry. Karen draws on her rich background to educate audiences large and small on how NOT to do safety, and, best practices to avoid penalties, negative reviews and the 6 o’clock news!

Our next guest on the Walk is a professor in the OSU College of Medicine, Dr. Michael Prats.Dr. Prats is a Clinical Assistant Professor at the Ohio State University Wexner Medical Center. He studied neuroscience and philosophy at the University of Pittsburgh, and received his medical degree from Ohio State. Dr. Prats serves as the Assistant Director of Ultrasound, and the Director of Ultrasound Research within the Division of Emergency Ultrasound. He founded and co-hosts his own podcast, the Ultrasound G.E.L. podcast, which discusses research articles in the field of bedside ultrasound. He's been invited to speak at conferences around the world in light of his work and interaction with ultrasound research.But Mike is more than a physician in academic medicine. Mike's wife Lyndsay has this to say about him:“One thing I love about Mike is his integrity. It makes him very trustworthy and dependable. He always tries to do the right thing, in every area of life, even when it is at a cost to himself.I also think he's really funny and he makes me laugh every day. He brings joy everywhere he goes.Listen in on Aaron's interview with Dr. Michael Prats.------Learn more about Dr. Prats at The Thompson Institute: https://thethompsoninstitute.org/about/faculty-fellows/michael-prats-medicine-Check out Dr. Prats' own podcast: https://www.ultrasoundgel.org/-----The Walk is a production of The Thompson Institute, a program of Cru at Ohio StateProduced by Aaron Badenhop & Jordan BrowningEdited by Seth Costello & Lukas MorelandMusic by Jordan BrowningSpecial thanks to Dr. Michael Prats

In episode 2 of our interview with Dr. Michael Prats, professor in the OSU College of Medicine, we ask him whether or not faith is something that is completely subjective, and we ask him if his faith is ever at odds with his work in the scientific field of medicine.------Learn more about Dr. Prats at The Thompson Institute: https://thethompsoninstitute.org/about/faculty-fellows/michael-prats-medicine-To explore more on the intersection of science, knowledge, and faith check out Ian Hutchinson's book: https://www.amazon.com/Monopolizing-Knowledge-Ian-Hutchinson/dp/0983702306-----The Walk is a production of The Thompson Institute, a program of Cru at Ohio StateProduced by Aaron Badenhop & Jordan BrowningEdited by Seth Costello & Lukas MorelandMusic by Jordan BrowningSpecial thanks to Dr. Michael Prats

Joe Ostrowski and Eli Hershkovich talk with Joey Knish -- aka gambling Twitter degen -- to breakdown the bigger games on the college football Week 9 card, including Wisconsin-Ohio State and Notre Dame-Michigan, along with his best bets. See omnystudio.com/policies/listener for privacy information. Learn more about your ad choices. Visit podcastchoices.com/adchoices

This month on the podcast we travel to the CloverNook Center for the Blind and Visually Impaired in Cincinnati, Ohio to hear about the Braille Challenge. We listen to excerpts from the Little NC pep rally held on March 7. Our little NC squad traveled to the Indiana School for the Blind and Visually Impaired to compete in wrestling, cheerleading, swimming and goalball. We hear from Jeff Ransey who works in the Conservation department at the Columbus Zoo. And why does OSSB have a chocolate fair every year? Stay tuned and find out. You will hear information about the alumni reunion taking place on the OSSB campus the first weekend in June. We catch up with some alumni and see what they are up to these days and we talk about bell Camp happening here on campus in July put on by the Ohio Chapter of the National Federation of the Blind. Andre and Mrs. Smith visit the OSU College of Optometry and conduct an informative reach and teach activity. We look at some new technology coming on the market for the blind and visually impaired with a visit from Jim Sullivan from Humanware. He discusses the features of the new BrailleNote Touch Plus. 3d printing is becoming ever so much more popular and OSSB is using 3d-printing in the model club with help from experts from see3d. See3D is designed to connect people who enjoy 3D printing with their visually impaired neighbors. Low vision and blind individuals can request models to give new meaning to words that some students have never been able to understand. We conclude this month’s podcast with another listen-in on a reach and teach activity with our students and the O&M department. They visit a Mennonite school and shared a great day of learning together. Thank you all so much for tuning in every month and supporting the students and staff at OSSB and all the things we do.

Summary: Tim is a Nurse, Entrepreneur, and the Chief Innovation Officer at the OSU College of Nursing. During his time in the healthcare industry, he’s researched a variety of fields including neurosurgical research on Tethered Spinal Cord Syndrome and improving patient throughput in ​the pediatric hematology/oncology ambulatory settings. He’s also an entrepreneur and an innovator, …

Michelle interviews Dr. Thompson, owner of Grandview Dental Care. Dr. Thompson opened his Grandview, OH practice in 1978, after graduating from the OSU College of Dentistry. Dr. Thompson talks about his 40-year career, and the changes that have happened in dentistry. Grandview Dental Care prides themselves on the results they create for their clients, utilizing state of the art technology and dental techniques to create beautiful smiles for each and every patient. https://www.grandviewdentalcare.com/ (https://www.grandviewdentalcare.com/) Thank you for downloading, listening and subscribing to Business Inspires, a TriVillage Chamber Partnership podcast, presented by The Village of Marble Cliff. With more than 60 years as an integral part of the Grandview, Upper Arlington and Marble Cliff communities, the TriVillage Chamber Partnership is dedicated to a singular purpose - the success of the business community. To schedule a guest appearance, or find out more about sponsoring Business Inspires, send an email to stephanie@chamberpartnership.org Please take a moment to rate and review our podcast in Apple Podcasts. That helps us spread the word about Business Inspires! Here's how - http://pleasereviewmypodcast.com/businessinspires (http://pleasereviewmypodcast.com/businessinspires) http://chamberpartnership.org/ (http://chamberpartnership.org/)

Super Bowl recap and NFL talk. The Cavs trade their entire roster at the trade deadline. OSU College hoops. Would you rather.

The month of August is National Eye Exam Month. Eye exams are not only important for maintaining clear and focused vision, but they can also give your eye doctor a better glimpse into your overall health. Dr. Michael Earley from the OSU College of Optometry talks about more reasons why you schedule your regular comprehensive eye exam during National Eye Health Month: 1. Detect Underlying Eye Conditions 2. Improve Children’s Performance in School 3. Keep Your Prescription Up-To-Date4. Prevention of headaches5. Different age groups have different and distinct eyesight and eye conditions6. What to expect in an examSubscribe to the podcast on Apple Podcasts, Stitcher, Google Play or iHeart Radio, or your favorite podcast player.HELP US SPREAD THE WORD!We'd love it if you could please share this podcast with your social media friends! If you liked this episode, please leave us a rating and a review in your podcast player.Discover more podcasts like this at Circle270Media Network - http://www.circle270media.com"Snap And All That" used with permission from Hayden Johnson. Created with Tize Music, 2017.Contact us at bjohnson@nabco-inc.com

The month of August is National Eye Exam Month. Eye exams are not only important for maintaining clear and focused vision, but they can also give your eye doctor a better glimpse into your overall health. Dr. Michael Earley from the OSU College of Optometry talks about more reasons why you schedule your regular comprehensive eye exam during National Eye Health Month: 1. Detect Underlying Eye Conditions 2. Improve Children’s Performance in School 3. Keep Your Prescription Up-To-Date4. Prevention of headaches5. Different age groups have different and distinct eyesight and eye conditions6. What to expect in an examSubscribe to the podcast on Apple Podcasts, Stitcher, Google Play or iHeart Radio, or your favorite podcast player.HELP US SPREAD THE WORD!We'd love it if you could please share this podcast with your social media friends! If you liked this episode, please leave us a rating and a review in your podcast player.Discover more podcasts like this at Circle270Media Network - http://www.circle270media.com"Snap And All That" used with permission from Hayden Johnson. Created with Tize Music, 2017.Contact us at bjohnson@nabco-inc.com

Tom Best, co-medical director of Ohio State University Sports Medicine and professor of Family Medicine, OSU College of Medicine, talks about his work on the treatment of hamstring injuries. 1.00 - Clinical scenario: acute hamstring injury 4.15 - Recovery time 9.34 - Considerations before returning to sport 17.00 - Recurrence 19.30 - Use of NSAIDs 23.30 - Role of massage in sports medicine injuries 26.20 - American College of Sports Medicine 2012 meeting in San Francisico 30.30 - Other hamstring injury resources See also: Carl Askling's BJSM podcast on hamstring injuries http://bit.ly/zFjobU BJSM article: Do you consider two types of injury? http://bit.ly/15Dzv8a Feb 2012 issue of BJSM http://bjsm.bmj.com/content/46/2.toc Tom also mentioned: Gisela Sole's paper http://bit.ly/10aHLnR Jan Ekstrand http://bit.ly/ZMbrHW Tom's book is Evidence Based Sports Medicine

Cowgirls advance in NCAA Tournament, OSU College of Education Hall of Fame 2008 and Chapters events.

Morsani donation to the OSU College of Education, Cowgirl Soccer earns birth in NCAA Tournament, Oklahoma Centennial and Chapters events.