In genetics and biochemistry, determining the structure of an unbranched biopolymer
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"Having grown up outside my country of origin, and subsequently returned as to a familiar-but-unfamiliar place, I have some insight into how it feels to have an outside perspective on the place where you live. "I found it interesting that the recording was made by someone able to view the sights & sounds of a place from an outsider's perspective, noticing sounds, colours and characters that others might not, but with a depth of familiarity and knowledge layered on. "I was charmed by the song being sung and whistled, and loved that the recording features animal, machine and human sound. The birds, machines & humans may well migrate, but subject to different constraints. I like the fact that the man singing is collecting recycling which may migrate to another location prior to processing (possibly to another country entirely). He is a part of a much larger system, but clearly asserts his humanity - far from a cog in a wheel. "It seemed inappropriate to impose a rigid tempo grid on such a freeform snatch of song, so the tempo adapts to the recording; it varies as time goes along. I enjoy listening to the machine adjusting to human cadence, hurrying to catch up and struggling to stay in sync. It seems a better that way round than the opposite, and we might be in a better world if more (including the way we think about migration) things worked that way. "Often field recordings (& just listening to the world!), provide enjoyable juxtapositions, fortuitous call & response patterns, whether intended or not, and I hope this piece succeeds in tapping into and replicating some of that energy. "All synth and drum sounds courtesy of a range of software and analog synths & drum machines. Sequenced in Logic Pro." Cartagena soundscape reimagined by Andrew Tulloch. Part of the Migration Sounds project, the world's first collection of the sounds of human migration. For more information and to explore the project, see https://www.citiesandmemory.com/migration IMAGE: Bybbisch94, Christian Gebhardt, CC BY-SA 4.0 , via Wikimedia Commons
AI Carlin was people; FTX not coming back; Neuralink implants a human; Yaccarino invents a new company; Senate hearing on online child exploitation; Universal pulls its music from TikTok; music piracy is back; Comcast forced to drop misleading 10G Network claim; 23andMe almost worthless now; FCC takes on AI-generated robocalls; Musk's bad week, Tesla sued, Musk loses case, voted most overrated CEO, SpaceX sued; Monarch: Legacy of Monsters; Eugene Levy; SiriusXM vastly overpays for SmartLess; Hulu cracks down on password sharing; Masters of the Air; Monsieur Spade; Star Trek ghost sex; Apple Vision Pro; Snap drone fireballs; AI & blockchain bullcrap; This Book May Save Your Life; Daily Laws & Daily Stoic.Sponsors:Mood - For 20% off your order and a FREE THCa pre-roll, go to hellomood.com and use promo code GOG.1Password - Get a great deal on the only password manager recommended by Grumpy Old Geeks! gog.show/1passwordPrivate Internet Access - Go to GOG.Show/vpn and sign up today. For a limited time only, you can get OUR favorite VPN for as little as $2.03 a month.Show notes at https://gog.show/634/FOLLOW UPThat AI-generated George Carlin comedy special was written by humansStudy finds that once people use cargo bikes, they like their cars much lessIN THE NEWSThank God FTX Won't Be Coming BackElon Musk Says Neuralink Has Implanted Its Chip in a Human for the First TimeX CEO Linda Yaccarino claims company has 90M US users, less than 1% are teensSenate tells social media CEOs they have ‘blood on their handsUniversal Music Group Warns It Will Pull Songs From TikTok After Deal ExpirationTikTok Is Thrown Into Disarray As Music From Taylor Swift, Ariana Grande DisappearsMusic Piracy Is Back in a Big Way—Especially From YouTubeComcast reluctantly agrees to stop its misleading “10G Network” claims23ANDME HAS LOST BILLIONS, ALMOST WORTHLESS NOWFCC moves to outlaw AI-generated robocallsiRobot and Amazon call it quits, terminate acquisition agreementTesla sued by 25 California counties for allegedly mishandling hazardous wasteHEAVY METAL DRUMMER COST ELON MUSK $55.8 BILLIONTesla Lawyer Cried at a Deposition Because He Loves Elon So MuchELON MUSK VOTED "MOST OVERRATED CEO" BY HIS COLLEAGUESSpaceX sued for negligence in accident that led to worker's comaMEDIA CANDYMonarch: Legacy of MonstersThe Reluctant Traveler with Eugene LevySmartLess Podcast Moves to SiriusXM in Exclusive $100 Million DealHulu is the latest streaming service to crack down on password sharingMasters of the AirMonsieur Spade22 Years Later, Cillian Murphy Might Return for 28 Years Later30 Years on, TNG's Ghost Sex Episode Remains as Unhinged and Awful as EverWilson Bethel's Bullseye Returning for Daredevil: Born Again (Exclusive)Richard Prince to Pay Photographers Over $650,000 In Copyright LawsuitsAPPS & DOODADSApple Has Sold Approximately 200,000 Vision Pro HeadsetsApple says the EU accounts for just 7% of its global App Store revenueSnap Recalls All of Its Selfie Drones Due to Fears They'll Become Flying FireballsSam Altman Says GPT-5 Will Be ‘Okay'How AI WorksHow AI Doesn't WorkThe promise and challenges of crypto + AI applicationsPivot: Deepfake Regulation, Media Layoffs, and Guest Chris DixonRead, Write, Own: Building the Next Era of the Internet by Chris DixonAT THE LIBRARYThis Book May Save Your Life: Everyday Health Hacks to Worry Less and Live Better by Karan RajanThe Daily Laws: 366 Meditations on Power, Seduction, Mastery, Strategy, and Human Nature by Robert GreeneThe Daily Stoic: 366 Meditations on Wisdom, Perseverance, and the Art of Living by Ryan Holiday, Stephen HanselmanThe stoics and the Sex Pistols: Philosophical roots of punk rebellion go back to ancient GreeceItchy by Teresa McNultySee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Welcome to Bri Books! This week, as we'll be delving into all things literary, starting with a review of the 6 best books I read in 2023. 'The War Before: The True Life Story of Becoming A Black Panther, Keeping the Faith in Prison & Fighting for Those Left Behind' by Safiya Bukhari. This book was probably my most valuable and important read of 2023. It's the true-life story of Safiya Bukhari, and it catalogues her lifelong commitment as an advocate for the rights of the oppressed. Following her journey from middle-class student to Black Panter to political prisoner, her wiritings provide an intimate view of a woman wrestling with the issues of her time, including the legacy of the Panthers, misogyny in the movement, her decision to convert to Islandm, the incarceration of outspoken radicals around the world, her passion for family, and how the struggles of social justice movements have paved the way for the progress of today. ‘Mother Hunger: How Adult Daughters Can Understand and Heal from Lost Nurturance, Protection, and Guidance' by Kelly McDaniel. This book came recommended by Myleik Teele, founder of Curlbox and host behind Myleik Teele My Taught You podcast. It's truly a life-changing and life-saving book. It comes with countless insights on so many things. Having parts of this book hit home has been enlightening and healing at a whole new level. With ‘Mother Hunger', McDaniel helps women break the cycle of destructive behavior by taking a fresh look at childhood trauma and its lasting impact. McDaniel is the first clinician to identify Mother Hunger, which demystifies the search for love and provides the compass that each woman needs to end the struggle with achy, lonely emptiness, and come home to herself. 'The Yoga Almanac: 52 Practices and Rituals to Stay Grounded Through the Astrological Seasons,' by Lisette Cherreson and Andrea Rice. Sequenced by the astrological calendar, The Yoga Almanac is a practical guide to help you reintegrate with recurring cosmic rhythms, and invite the sacred into your life through learning, movement, breath, and ritual. Featuring 52 seasonally-themed chapters, the Almanac is a comprehensive jumping off point to deepen your relationship to yoga—and to yourself. ‘Forbidden Fairways: African Americans and the Game of Golf' by Calvin H. Sinnette.: The emergence of Tiger Woods on the international golf scene brought the world's attention to the African American experience in golf. But before Tiger, names like Ted Rhodes, Bill Spiller, Ann Gregory, and so many others remained in relative obscurity without being given the chance to compete. ‘Forbidden Fairways' is not just a history of the African Americans who have been playing golf for over 200 years but a tribute to them as well. ‘Spare' by Prince Harry, Duke of Sussex. Spare. Spare! WHAT can I even SAY about the book that kicked off 2023? For the first time, Prince Harry tells his own story, chronicling his journey with raw, unflinching honesty. A landmark publication, Spare is full of insight, revelation, self-examination, and hard-won wisdom about the eternal power of love over grief. From losing his mother, Princess Diana, as a tween to joining the British Army before meeting Meghan Markle his future wife, Harry spared nothing and no one in ‘Spare.' ‘Slow Living: The Secrets to Slowing Down and Noticing the Simple Joys Anywhere' by Helena Woods. This is a fantastic book that breaks down how to inject more calmness, stillness, and intentionality into your daily life. A must for 2024 and beyond!
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In Paul's letter known to us as “Ephesians,” Paul indicates an historical sequence by which his readers came to be included in the foreordained purposes of God. This and other insights arise as Matthew Bates, making a second appearance in our podcast series, takes us through a reading of the Greek text of Ephesians 1. Dr. Bates is Professor of Theology at Quincy University (Quincy, IL). Among his several publications are The Birth of the Trinity(Oxford, 2015) and Gospel Allegiance: What Faith in Jesus Misses for Salvation in Christ.
Twenty years after the first pass at sequencing the entire human genome, the Y chromosome has finally been fully decoded. Madeleine Finlay speaks to Mark Jobling, professor of genetics at the University of Leicester, about why it has proved so tricky, the role of the Y chromosome in our bodies, and the likelihood of it eventually dying out altogether. Help support our independent journalism at theguardian.com/sciencepod
Sequenced Collections, targeted for JDK 21, are a new collection type created to represent a sequence of elements with a defined encounter order. Ana recorded this episode with Stuart Marks, the owner of JEP 431 about Sequenced Collections. Stuart discusses the essence of Sequenced Collection interfaces, what needs those address and how they fit within the existing Collections framework. He explains the design of Sequenced Collections, architectural decisions and particularities of the API. He also shares his view on how Sequenced Collections can inspire future Java platform developments.
Eversines returns to Pieter Jansen's yeyeh/ninih platform with his second solo album, Dwang, an evocative sonic exploration of the themes of inner struggles and personal growth. Sequenced like a DJ set, Dwang traverses dreamy ambient, breaks, acid techno, and trance over four sides of vinyl, telling a compelling story about the peace we can find when we yield to a higher flow. The track "Elev" by Eversines is an energetic and pulsating acid-infused breakbeat track. With its infectious beats and intricate melodies, the track is reminiscent of the electronic music of the late '90s and early '00s, when breakbeat and acid were at their peak. The track is characterized by its driving rhythm, intricate synths, and acid bassline, which create a hypnotic and almost trance-like atmosphere. Eversines has successfully blended the old-school acid sound with modern production techniques to create a track that is both nostalgic and fresh. Dwang LP is coming out on April 20, 2023 https://soundcloud.com/eversines https://soundcloud.com/ye_yeh https://www.instagram.com/eversines/ https://www.instagram.com/pieterjansen_yeyehninih/ www.itsdelayed.com www.instagram.com/_____delayed/ www.facebook.com/itsdelayed
We make sure everything is in its right place this week, because we're talking about the albums with the best track sequencing. Like a great book or movie, a great record has an artistically satisfying beginning, middle and ending. We go waaaaaaaay back with the music of this week's Third Lad...like two, maybe three weeks? During our recent Animal Songs episode, Graham Kemp from Urusei Yatsura chose the song "Bugs" by fellow Scottish band Spare Snare. Not being previously familiar with the band, we took a crash course in Spare Snare's music, listening to and loving everything they've put out in their 30+ year career. Fast forward a few weeks, and now minted as superfans, it is our great pleasure to welcome singer/songwriter/guitarist Jan Burnett from Spare Snare! Spare Snare's marvelous new album, The Brutal, will be out May 12th. It is their second album (and first of all-new material) to be recorded by the legendary Steve Albini. As a special treat for O3L listeners, we've got an exclusive first listen to one of the tracks from the album called "Wifi." Listen for the answers to these hard hitting questions and more: - Is Jan a fan of the Dan? - Is he really Scottish? - What's it like to be voted the 46th best band in Scottish music history? - What's under the kilt? - Is Steve Albini a magic genie?
References Hum Genomics. 2021; 15: 24 JCI Insight. 2020 Sep 3;5(17):e138443 Nature Reviews Genetics volume 14, pages 204–220 (2013) --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
This mix is much more straightforward than the Antarctica set. This mix follows my "dubby & dreamy" formula of ethereal ambient dub tracks with a few gentle beats and lots of synth washes. Here are the links to all the music used in this mix: https://richiehawtin.bandcamp.com/album/consumed-in-key https://ultimae.bandcamp.com/album/onwards-system https://ultimae.bandcamp.com/album/isolated https://arcticdub.bandcamp.com/album/arctic-dub-sursumcorda-compilation-v5 https://shop.silentseason.com/album/infinite-horizon https://ultimae.bandcamp.com/album/gneiss-ep https://faintmusic.bandcamp.com/album/north-paths https://motionfield.bandcamp.com/album/optical-flow https://earthensea.bandcamp.com/album/grass-and-trees https://asc77.bandcamp.com/album/sequenced https://driftdeeper.bandcamp.com/album/mr-zu-driftwood-ep-ddr017 https://echospacedetroit.bandcamp.com/album/starlight https://shop.silentseason.com/album/entire Cheers! T R A C K L I S T : 00:00 PLastikman & Chilly Gonzalez - Ekko(In Key) (Consumed In Key 2022) 03:39 CELL - Onwards System - Fugitive Perpetuity (Onwards System 2022) 09:00 ASC - Solitude (Ultimae Records - Isolated 2022) 12:10 Solar Debris - It's All Dark When You Are Gone (Arctic Dub Compilation 2019) 16:50 Owl - Distant Transmission (Infinite Horizon 2021) 20:20 EROT - Observer Effect (Gneiss EP 2021) 24:50 MYKJA - Vera Á Reiki (North Paths 2017) 32:40 Motionfield - Midnight Metro (Optical Flow 2014) 38:32 Earthen Sea - Shallow, Shadowless (Grass & Trees 2019) 43:20 ASC - Sequence 4 (Sequenced 2017) 47:00 Mr Zu - Echova (Driftwood EP 2016) 53:00 Model 500 - Starlight(Intrusion dub) (2008) 57:45 Daar - Coda (Entire 2021) 60:00 end
Ferns may have an ancient evolutionary history and enjoy something of a celebrity status among the botanically and non-botanically minded alike, but a fully sequenced fern genome has been hard to come by... until now. Join me and Dr. Blaine Marchant as we explore what it took to sequence the genome of the water fern (Ceratopteris richardii) and all of the amazing discoveries and questions they have unlocked. From massive its massive genome to its ability to steal genes from bacteria, this fern has a lot to teach us about life as we know it. This episode was produced in part by Susan, Corbin, Keena, Robin, Peter, Whitney, Kenned, Margaret, Daniel, Karen, David, Earl, Jocelyn, Gary, Krysta, Elizabeth, Southern California Carnivorous Plant Enthusiasts, Pattypollinators, Peter, Judson, Ella, Alex, Dan, Pamela, Peter, Andrea, Nathan, Karyn, Michelle, Jillian, Chellie, Linda, Laura, Miz Holly, Christie, Carlos, Paleo Fern, Levi, Sylvia, Lanny, Ben, Lily, Craig, Sarah, Lor, Monika, Brandon, Jeremy, Suzanne, Kristina, Christine, Silas, Michael, Aristia, Felicidad, Lauren, Danielle, Allie, Jeffrey, Amanda, Tommy, Marcel, C Leigh, Karma, Shelby, Christopher, Alvin, Arek, Chellie, Dani, Paul, Dani, Tara, Elly, Colleen, Natalie, Nathan, Ario, Laura, Cari, Margaret, Mary, Connor, Nathan, Jan, Jerome, Brian, Azomonas, Ellie, University Greens, Joseph, Melody, Patricia, Matthew, Garrett, John, Ashley, Cathrine, Melvin, OrangeJulian, Porter, Jules, Griff, Joan, Megan, Marabeth, Les, Ali, Southside Plants, Keiko, Robert, Bryce, Wilma, Amanda, Helen, Mikey, Michelle, German, Joerg, Cathy, Tate, Steve, Kae, Carole, Mr. Keith Santner, Lynn, Aaron, Sara, Kenned, Brett, Jocelyn, Ethan, Sheryl, Runaway Goldfish, Ryan, Chris, Alana, Rachel, Joanna, Lori, Paul, Griff, Matthew, Bobby, Vaibhav, Steven, Joseph, Brandon, Liam, Hall, Jared, Brandon, Christina, Carly, Kazys, Stephen, Katherine, Mohsin Kazmi Takes Pictures, Manny, doeg, Daniel, Tim, Philip, Tim, Lisa, Brodie, Bendix, Irene, holly, Sara, and Margie.
The rapid growth of genetic databases worldwide, coupled with fast-decreasing costs and increased technological speed, has raised the possibility of every human genome on Earth being sequenced within this century. This brings to the forefront ethical and legal questions on data privacy and ownership. While a world genomic database would revolutionise preventive medicine and research, new forms of surveillance, discrimination and power imbalances could emerge. The global interplay between the individual, the state and private individuals could shift, requiring modern and flexible legislation to protect the rights of the individual. - Original publication on the EP Think Tank website - Subscription to our RSS feed in case your have your own RSS reader - Podcast available on Deezer, iTunes, TuneIn, Stitcher, YouTube Source: © European Union - EP
Sequenced by Brother-In-Crime 01. Sam Feldt feat. Kimberly Anne - Show Me Love 02. R3hab & Quintino - Freak (Sam Feldt Remix) 03. Kygo feat. Conrad - Firestone 04. FRENSHIP + Emily Warren - Capsize 05. JP Cooper - September Song 06. Justin Bieber - Sorry 07. Marvin Gaye - Sexual Healing (Kygo Remix) 08. Coldplay - Hymn For The Weekend (SeeB Remix) 09. Ed Sheeran - Shape Of You 10. Charlie Puth feat. Selena Gomez - We Don't Talk Anymore 11. Ian Storm, Carl Clarks & John Laurant - California Dreamin' 12. Felix Jaehn ft. Jasmine Thompson - Ain't Nobody (Loves Me Better) 13. Dua Lipa - Hotter Than Hell 14. Faul & Wad Ad vs Pnau - Changes 15. GOLD RVSH & Miya Miya - Never Too Much 16. OMI - Cheerleader 17. Lost Frequencies ft. Calum Scott - Where Are You Now 18. Bob Marley ft. LVNDSCAPE & Bolier - Is This Love 19. Nora En Pure - Come With Me 20. Sigala & Ella Eyre - Came Here For Love 21. Israel Kamakawiwo'ole - Somewhere Over The Rainbow / What A Wonderful World MORE BANGERS & MASH ▶️ bit.ly/RA_Bangers reactivateasia.com RE-ACTIVATE ON FACEBOOK - bit.ly/reactasiaFB RECOMMENDED APP
Guest: Dr. Fabio Macciardi, a Professor of molecular psychiatry at the University of California. He is part of a team of geneticists and archaeologists that have successfully sequenced the genome of a man who died after the eruption of Mount Vesuvius in 79 AD for the first time. See omnystudio.com/listener for privacy information.
Matthew Sweeney - Sequenced vs. Vinyasa Flow Practice (A Deep Dive)Welcome back a NYT favorite guest, Matthew Sweeney, for a DEEP DIVE discussion on Sequenced vs. Vinyasa Flow Practice. Listen to Matthew explain in great detail the benefits and drawbacks of both sequenced yoga routines and "free flow" vinyasa style practice and how to utilize and benefit from both. Hear him explain the intricacies of the relationship of the nature of freedom and restriction that can evolve from both these approaches. Matthew also explains protocols he uses as a teacher to help students heal injury and thrive in their yoga practice. This is an informative discussion you want to miss!Visit Matthew at his website www.yogatemple.com to learn more about his online courses and in person study with him on the island of Bali, Indonesia.Matthew is the Author of Astanga Yoga ~ As It is and Vinyasa Krama as well as several other books.Matthew has spent the last 30 years practicing Ashtanga and Vinyasa Yoga and different forms of self inquiry, including Meditation, Tantra, Gestalt Therapy, Transpersonal Therapy, Transforming Cellular Memory, Buddhism and Advaita Vedanta. All of these have contributed greatly to his understanding of Yoga and the connection between the body, Self, and the Divine.Matthew lives in Bali, Indonesia at his yoga shala called the Vinyasa Krama Mandiram. Visit him at www.yogatemple.com. You can also find him on Facebook at VKM Online Classes. The Vinyasa Krama Mandiram is located in Ubud, Bali and Matthew offers course both online and in person in Bali.Thanks for listening to this episode. Check out:
The Human Genome has finally been fully sequenced by scientists for the first time, 33 years after the human genome sequencing project began. Now we know more about the human code than ever before (00:30:44). Elon Musk went ahead and bought almost 10% of Twitter becoming the largest single shareholder because he can (00:19:51). A man masturbated four times to a woman he was sitting next to on a plane and won't be flying anymore (00:53:09). (00:00:00) - Timestamps Cup of Coffee in the Big Time (00:02:38) - Fun Fact - From 1932 to 1967 the Nevada state prison had a casino in it for the inmates (00:05:17) - Holidays - National Deep Dish Pizza (00:06:17) - World Cup draw is wild for the US (00:07:17) - The House passed the More Act for marijuana but the senate is probably going to not pass it (00:09:45) - Conservatives are supporting Madison Cawthorn's competitor (00:12:21) - The Senate Judiciary Committee deadlocked for Supreme Court nominee Ketanji Brown Jackson and the real vote will be next week (00:12:45) - The Sacramento police arrested a 26 year old in the deadly shooting from the weekend (00:13:25) - Kanye might be taking the 5 million he was paid to headline Coachella and running. Swedish House Mafia might be replacing him (00:19:51) - #1 - Elon Musk purchased a 9.2% stake in Twitter making him the largest single shareholder and Trump's platform Truth social is losing two executives that were chief technical members Scientists Have Finally Done it (00:30:44) - The complete human genome sequence has been created by scientists 33 years after the genome project began and was stuck at 92% for the past 20 years TikTok International Moment (00:39:13) - Ukraine - Small town civilians in Ukraine have been getting back at Russian soldiers that have been trying to kill them by giving them poisoned food (00:44:25) - NASA scientists are ignoring Stephen Hawking's warnings to not contact aliens and tell them where earth is and are doing exactly that Excitement on a Plane (00:53:09) - A man jerked off to a woman he was sitting next to four times on a Southwest flight and was arrested and has a life time flying ban now These stories, and much more, brought to you by our incredible sponsors: Harry's - New Harry's customers can redeem a Starter Set. You get a five-blade razor, a weighted handle, foaming shave gel with aloe, and a travel cover to protect your blades when you're on the go. That's a $13 value for just $3. http://Harrys.com/HARDFACTOR to try Harry's today. Caliper CBD - Get flavorless with Caliper CBD! Get 20% off your first order with promo code FACTOR at http://trycaliper.com/FACTOR. Go to store.hardfactor.com and patreon.com/hardfactor to support the pod with incredible merch and bonus podcasts Leave us a Voicemail at 512-270-1480, send us a voice memo to hardfactorvoicemail@gmail.com, and/or leave a 5-Star review on Apple Podcasts to hear it on Friday's show Other Places to Listen: Spotify, Google Podcasts, Stitcher, Lots More... Watch Full Episodes on YouTube
Will Smith RESIGNS from The Academy, Amazon Labor Union scores its first HUGE victory & we've finally sequenced the entire human genome
ATTENDEES Zilla Rocca, Keith Rollins, Daniel Olney AGENDA New Business Talk about the mission for the new album Never At Peace and the reaction it has gotten. Discuss the importance of album sequencing. Intro bumper is the title track of Never At Peace. Outro is Dame Dash Taught Me. Buy Never At Peace here: https://wreckingcrew.bandcamp.com/album/never-at-peace
Molecular Testing PearlsIn Part 4 of our Heme Path series, we thoroughly examine the details of molecular testing and how it relates to hematologic and oncologic malignancies I. Molecular Testing BasicsA. Provides a means of assessing patient's genotypes, specifically at smaller changes in the genetic information B. How is it performed?1. Polymerase chain reaction (PCR)-based testing, which involves using a specific primer that is complementary to the area of interest on the patient's DNA2. PCR can allow for both amplification and quantification of gene of interest C. Can look for either single gene mutations (faster) or a panel of mutations (slower but more information) also known as NGSII. Clinical Utility of Molecular TestingA. Very useful in risk stratification based on the mutations noted (some mutations are unfavorable and some are favorable)B. Certain genetic mutations have drugs that are effective against them, therefore provides information about targeted therapeutic options C. In hematologic malignancies, can be used to also assess response to treatment1. You can determine minimal residual disease or MRD2. Can look for a gene mutation that was present in the original cancer clone and see if there is any amount of residual cancer left over on the order of 1 in a million cellsD. In solid cancers, used to determine presence of genetic changes that have prognostic and targeted treatment implications1. BRAF V600E mutation in melanoma → BRAF inhibitor pill treatment2. EGFR mutation in lung cancer → EGFR inhibitor pill treatmentIII. How is molecular testing different than FISH?A. Both require choosing probes and understanding what you are looking for before running the testB. FISH (discussed in part 3!) reports out of 200 cells and provides information about only larger kilobase sized genetic changes (translocations, inversions, deletions)C. Molecular testing analyzes a much larger number of cells and can detect changes at the single base pair level. Much more detailed and microscopic evaluation of genetic changesIV. Single Gene Molecular TestingA. Look for a specific gene mutation (i.e. EGFR for lung cancer, BRAF for melanoma, FLT3-ITD for AML)B. Pros: 1. Faster turnaround time 2. Has a higher resolution and effective for detecting MRDB. Cons:1. Only looks for one genetic mutation as opposed to a panel like in NGS2. Some diseases ideally require understanding of multiple mutations not just one for prognostication and treatment planningV. Next Generation Sequencing (NGS)A. Allows to sift through a larger part of the genome to identify a panel of mutations B. Panel of mutations chosen is based on the clinical context1. For example: NGS for acute myeloid leukemia is much different than NGS testing for lung cancer as each cancer has a much different genetic mutation profileC. Overview of technical aspects of running NGS1. Massively parallel sequencing meaning that many tiny primers are used and the areas that primers encode may be overlapping2. A computer takes all of the smaller pieces and puts them together to determine the correct sequenceD. Pros:1. Gives us an understanding of many different mutations present based on the panel chosen2. Again, this has both prognostic and predictive treatment implicationsE. Cons:1. May find mutations of undetermined significance meaning we currently do not understand how these mutations will affect prognosis and treatment decisions2. Very time consuming (~2-4 week turnaround time)3. CostlyReferences:1. https://jamanetwork.com/journals/jamaoncology/fullarticle/2734828 - Quick overview of NGS2. https://ashpublications.org/blood/article/125/26/3996/34323/Minimal-residual-disease-diagnostics-in-acute - Look at table 1 to see the difference in sensitivity for MRD testing3. https://www.oncotarget.com/article/27602/text/ - Emphasizes prognostic relevance of EGFR mutations in NSCLC4. https://www.nejm.org/doi/full/10.1056/NEJMoa1612674 - Phase 3 trial showed that targeted treatment for EGFR mutation in NSCLC was superior to chemotherapy5. https://www.nejm.org/doi/full/10.1056/nejmoa1614359 - Phase 3 trial showed that targeted treatment of FLT3 mutation in AML improved outcomesPlease visit our website (TheFellowOnCall.com) for more information Twitter: @TheFellowOnCallInstagram: @TheFellowOnCallListen in on: Apple Podcast, Spotify, and Google Podcast
Episode 55 Drum Machines: A Recorded History, Part 2: Digital Drum Machines Playlist Linn Drum Gary Numan, “My Brothers Time” from Dance (1981 Beggar's Banquet). Early use of the Linn LM-1 by John Webb on this track. Note the sound of the claves, played by Numan but not digital. Bass, Saxophone, Mick Karn; Linn LM-1 drum machine, John Webb; Piano, Claves, Gary Numan. 4:37 Rajie, “ストーミー・ナイト (Stormy Night)” from Acoustic Moon (Sony 1981). Early recognition in Japan of the original Linn LM-1 drum machine. Rajie, vocals; Guitar, Mikihiko Matsumiya; Bass, Tsugutoshi Goto ; Chorus, Hiroshi Koide, Raji ; Composed By, Akira Inoue ; Drums, Tatsuo Hayashi ; Electric Guitar-Tsuyoshi Kon; Flute, Motoya Hamaguchi ; Lyrics By, Etsuko Kisugi ; Percussion, Motoya Hamaguchi ; Prophet-10, Linn LM-1, Electric Piano, Akira Inoue. Early Linn Drum Computer. 5:08 Herbie Hancock, “The Twilight Clone” from Magic Windows (1981 Columbia). If you want to study the latest in emerging electronic music instruments, just listen to the many albums by Herbie Hancock throughout the 1970s and 1980s. He was an early adopter of the Linn LM-1, heard here and played by Hancock. Bass, Louis Johnson; Linn LM-1 Drum Machine, Herbie Hancock; Ghanian Drums, Moody Perry III; Ghanian Drums, Bells, Kwasi Dzidzornu, Kwawu Ladzekpo; Lead Guitar, Adrian Belew; Percussion, Paulinho Da Costa; Rhythm Guitar, George Johnson; Written by, A. Belew, H. Hancock. 8:16 Don Henley, “The Boys of Summer” Linn Drum demo version (excerpt) (1984 private). Guitar and Linndrum, Mike Campbell; Synthesizer, Steve Porcaro; Synthesizer, Guitar, Danny Kortchmar. Bass, Larry Klein; vocals, lyrics, Don Henley. The instrumental part of the song came first and was put together by Tom Petty bandmate Mike Campbell who had just purchased a LinnDrum machine which was a more affordable model than the original LM-1 released in 1980. Campbell put together a rhythm track and played some guitar. Tom Petty wasn't interested in the song at that time, so it went to Henley, who wrote the lyrics. This demo was close to the final version. The final mix of the song also included some human drumming, as did live performances where a human drummer tried to replicate the sound of the original Linndrum. 0:42 Jean Michel Jarre, “Zoolookologie” from Zoolook (1984 Disques Dreyfus). A fascinating exploration of samples both of voice and drums. This is the later version of the Linn Linndrum machine, just before the introduction of the Linn 9000. There is pure joy in this track as Jarre uses the Linndrum to create many unexpected sounds and atypical rhythms. Bass, Marcus Miller; Composer, Producer, Ethnic Vocals Processing, Keyboards, Electronics, Jean-Michel Jarre; Drums, Yogi Horton; Daniel Lazerus; Guitar Ira Siegel; Guitar, Effects, Adrian Belew; Keyboards, Frederic Rousseau. 4:13 David Van Tieghem, “In-A-Gadda-Da-Vida” from In-A-Gadda-Da-Vida (1986 Wide Angle). Drummer and percussionist Van Tieghem created this version of the Iron Butterfly song using electronic drums (Octapads) and digital drums. Engineer, Programmed By Fairlight Programming Assistance, Eric Liljestrand; Guitar, Larry Saltzman; Vocals, Synthesizer Digital, Analog, Percussion Acoustic, Electronic, Mixed By, Producer, David Van Tieghem; Written-By, Doug Ingle. Basically a one-person performance aside from guitarist Saltzman. Van Tieghem was using both hand played electronic drums (the Octapads) plus some digital drum machines. 5:36 Suzanne Ciani, “Mosaic” from Neverland (1988 Private Music). Composed, Arranged, Performed, Produced by Suzanne Ciani. Among the many electronic instruments used by Ciani were keyboards made by Yamaha, Roland, and Bode (vocoder). For drum programming, she turned to the Linn 9000. This track has some decidedly simple, yet complex rhythms using the Linn 9000 that are truly nuanced and more jazz like. The care with which she programmed this track is in contrast to the typical drum machine beats you hear on records. Ciani also used a Roland TR-707 on this album, which you may also detect on this track. 4:37 Oberheim DMX Todd McKinney, “Kimberlite” from The Sound Of The System (1982 Oberheim). This 7-inch demo disc includes music created by Todd McKinney and Daniel Soger, two Oberheim employees. “Kimberlite” was composed and performed by McKinney using the DMX Programmable Digital Drum Machine, the DSX Digital Polyphonic Sequencer, and the OB-Xa Polyphonic Synthesizer. 2:28 Tangerine Dream, “Poland” from Poland (The Warsaw Concert) (1984 Jive Electro). You can hear the Bohn Digital Drums in the first half of the song and the Oberheim DMX in the second half. But that's a bit of a guess. Dr. Böhm DIGITAL DRUMS was a rhythm machine made in Germany from 1982-83, also known as ''the German Linndrum.'' Composed, performed, and produced by Tangerine Dream. Jupiter 8, PPG Wave 2.3 Waveterm, Minimoog, Korg Monopoly, Sequenced by EEH CM 4 Digital Sequencer, Bohm Digital Drums, Roland Tr 808 Drums, Roland SDE 3000 Delay, MXR 01 Digital Reverb, MXR Digital Delay, Johannes Schmoelling; Prophet 5, Prophet 600, Prophet 1, E-mu Custom Programmable Synth, Moog Custom Programmable Modular Synth, MTI Synergy, Sequenced by the PE Polyrhythmic Sequencer, Compulab Digital Sequencer, Syntec Custom Digital Drum Computer, Electronic Drums Simmons Drum Modules, Effects Quantec Room Simulator, Roland SDE 3000, Electronics Hill Multi-mixer, Chris Franke; Yamaha DX 7, Yamaha YP 30, Jupiter 8, Jupiter 6, Prophet 5, PPG Wave 2.2, Sequenced By Pe Polyrhythmic Sequencer, EEH Cm 4 Digital Sequencer, PE Custom Trigger Selector, DMX Oberheim Digital Drum machine, Edgar Froese. 8:43 Herbie Hancock, “Earth Beat” from Future Shock (1983 Columbia). In addition to the DMX, this track includes evidence that Garfield Electronics Dr. Click Rhythm Controller was a much-needed rhythm device for wrangling the otherwise incompatible signals prior to the introduction of MIDI a few years later. Craig Anderton wrote the following about Doctor Click in an article in Keyboard from 1983: "Doctor Click is not a keyboard instrument, not a drum machine, and not a signal processor: What it does is synchronize and interface these three families of devices together. Not only can it interface to existing sync tracks, it can build up click tracks from incomplete click tracks, and even create sync and/or click tracks which are referenced to a live musician." Hancock masters Dr. Click on this album. Fairlight CMI, Yamaha GS-1, Yamaha CE-20, Dr. Click Rhythm Controller, Herbie Hancock; DMX Drum Machine, Synare Electronic Drums, Memory Moog Programming, Michael Beinhorn; Bass, Bill Laswell; Bata, Daniel Ponce; Turntables – Grandmixer D. ST. 5:09 Herbie Hancock, “Hardrock” from Sound System (1984 Columbia). The sound of the Oberheim DMX digital drum machine as used by Herbie Hancock. This album was his follow-up to the album Future Shock on the DMX made a famous appearance in the song Rockit, which was unusually a top-selling hit for Hancock. The DMX is played here by non-other than Bill Laswell. Note that Simmons electronic drums are also being played on this track by Anton Fier, but I think you can tell the difference. Bass, Drum Machine DMX, Tape, Bill Laswell; Bata, Daniel Ponce; Simmons electronic drums, Sound Plates, Cuica, Anton Fier; Guitar, Henry Kaiser, Nicky Skopelitis; Fairlight CMI Programming, Will Alexander; Fairlight CMI, Rhodes Chroma, Apple IIe, Yamaha DX7, Emu 4060 Digital Keyboard, Herbie Hancock; Synthesizer (XMD), Rob Stevens; Turntables, D. St; Written-By, B. Laswell, D. Showard, Herbie Hancock. 6:10 Davy DMX, “Bonus Beats” from One For The Treble (Fresh) (1984 Tuff City). Davy DMX when he first met the Oberhheim DMX digital sampling drum machine. He is also known as David Franklin Reeves, Jr. Here is a bonus track of only drum machine and turntable. 1:47 Davy DMX, “One For The Treble (Fresh) (Instrumental)” from One For The Treble (Fresh) (1984 Tuff City). Davy DMX when he first met the Oberheim DMX digital sampling drum machine. Another track from that same 12-inch. 7:31 Movement MCS Drum Computer John Foxx, “Pater Noster” from The Garden (Virgin 1981). This album was produced after Foxx left Ultravox. It is another example of the MCS Drum Computer. This track only features Foxx on synthesizers, voice, drum programming, and a manually struck Tom Tom. 2:30 Roland El Escuadrón Del Ritmo, “Las Cucarachas” from Back Up: Mexican Tecno Pop 1980-1989 (2021 Dark Entries). I discovered this wonderful collection of Mexican synth-pop tracks, some never before heard, and immediately dug-out a track using a drum machine. This track is from 1982. In this case, the drum machine is the Roland Compu-Rhythm CR-78, which was a transitional analog device with analog drum sounds and digital control for programming patterns. 3:44 Nahtabisk, “La Dama De Probeta” from Back Up: Mexican Tecno Pop 1980-1989 (2021 Dark Entries). Another hidden gem from Mexico. This track is from 1984 and features the Roland drumTR-606 Drumatix. The TR-606 featured PCM-encoded sounds of real drums. This small device, that ran on batteries, helped define the sound of early techno. 3:20 E-mu Joe Mansfield, “Drumulator (Instrumental)” from Drumulator (2014 Get On Down). This is a track featuring the sounds of the E-mu Drumulator that was sold from 1983 to 1985. It had twelve, 8-bit sampled sounds of real drums and at about $1000 was more affordable that drum machines like the Linndrum and Oberheim DMX. It was created on the heels of the sample synthesizers they made under the Emulator name. It also had a relatively short life so few recordings from the time were made. This demo is an example of what could be done with the Drumulator and Herbie Hancock took a liking to it prior to switching to the Oberheim DMX. 2:02 Richard Souther, “Uncharted Waters” from Innermission (1986 Meadowlark Records). Music and realization by Richard Souther. Includes synthesizers from Roland, PPG, Sequential Circuits, and Casio. He also used both the Linn 9000 and E-mu SP-12 drum machines, which are both heard on this track. You can clearly hear the Linn 900 and its distinctive snare and bass sounds, while the E-mu, which was built around the circuits in the company's popular keyboard samplers, provided some of the more unusual, even exotic, percussion sounds. 3:23 Alesis Slant, “Sheep” and “Ducks” from Hive (1989 These Records). This amazing group, although short-lived, was a British experiment in rock with noise elements that included Cris Cheek, Philip Jeck, Sianed Jones, and Osian Tam. Cross used an Alesis HR-16, which is showcased in the second of two tracks, “Ducks.” I think that is probably the same drum machine in the first track, “Sheep” so I thought this represented some good contrast in the way that the sound could be treated. This had 49 digital samples of drums that could be programmed in real-time by playing the velocity sensitive drum buttons. Double Bass Julia Doyle; Guitar, Cabasa, Engineer, Co-producer Maciek Hrybowicz; Keyboards, Accordion, Synthesizer DX7; Piano, Clarinet, Voice, Marimba, Goblet Drum Darabouka, Tambourine, Bells Agogo Bells, Sampler Cassette Samples, Flute Souffara, Rattle Seed Pod Rattles, Performer Emax, Alesis HR-16, Breath Rhythms, Face Slap, Mixed By, Co-producer Cris Cheek; Turntables, Radio Philip Jeck; Violin, Piano, Vocals, Organ, Fife, Viol Viola Da Gamba, Harmonium, Claves, Performer Emax, Breath Rhythms, Mixed By, Co-producer Sianed Jones; Voice Osian Tam. 4:31 Closing, Linn LinnDrum Mikel Rouse, “Quorum part 2” from Quorum (1984 Club Soda Music). It was inevitable that a composer would create an extended piece of music using only the Linn Linndrum. Mikel Rouse was that person. Listen to the hypnotic patterns of this work. From the composer's notes: “Quorom is a piece for LinnDrum machine (or 18 percussion players) in 9 parts running approximately 1 hour and 45 minutes in length. Though the sequence of parts 1 through 9 must be maintained, the parts may be divided into sections, or run continuously. Themes are produced through the synchronization of the 3 generators, 3-5-8, and their complimentary factors yield counterthemes. Power series are then applied to produce harmonic contrasts from the original themes. Thematic material is developed through multiple variation techniques (circular permutations, accents through superimposition of an additional component, natural growth through the summation series). I decided to undertake the programming myself and, with the aid of Jim Bergman, successfully completed the programming in about 5 hours. I would like to stress that all programming was done through the step-by-step process provided in the operator's manual for construction “songs” from “patterns”. No special treatments or extensions (including cassette interfaces) were required.” Such was the versatility of the Linn Linndrum. 11:16 Background Sounds Volti, “Corazón” from Back Up: Mexican Tecno Pop 1980-1989 (2021 Dark Entries). Mexican electro-pop group. This track is from 1986 and features unknown drum programming. vocals, synthesizer, Lyndell Brookhouse; bass, synthesizers, drum programming percussion, Eddie Rubello; Backing Vocals, Katie Taylor; Congas, Edgar Herrera; Piano, Vincent Kenis; Timbales, Pedro Ortiz. 3:45. Adams and Fleisner, tracks “a1, a2, b1, b2, b3” from Modern Digital Recorded Drumcomputer Rhythm Tracks (1983 Break Records). I think this track of library digital drum samples from the Netherlands was made with the Drum Computer MCS II (or Percussion Computer) from Movement Computer Systems, a rare British made-drum machine circa 1983. It had an integrated CRT monitor and had an orange (or black) case. It used 8-bit samples of drums and featured 14 voices and programmable patterns. Opening: Opening and closing sequences voiced by Anne Benkovitz. Additional opening, closing, and other incidental music by Thom Holmes. For additional notes, please see my blog Noise and Notations. There are dozens of drum machines that dot the history of electronic music. For an encyclopedic list of almost every drum machines ever made, and there were dozens of variations and models up until around 1985, check-out the excellent books by Alex Graham, a UK-based drum machine collector and specialist.
For Whom the Cell Tolls: Biology, Cancer, and Other Stories About Life
What do you think? Would the immensely powerful amount of data be a game-changer for medicine? Or does DNA sequencing miss too much of the picture to be worth the cost? This question is an example why we need leaders that understand Biology as genomics becomes hyper-accessible. I do my best to discuss the primary Pros and Cons of each side, along with possible modifications to the proposal. I hope you enjoy it! --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app --- Send in a voice message: https://anchor.fm/keenan-t/message
We premiere Scottish electronic music royalty, Vince Watson. The now Netherlands based artist returns for his incredible 13th album, which is no mean feat for any musician. Vince has had a massive year with releases on Get Physical, Tronic, SushiTech, All Day I Dream, his own Everysoul Audio and a host of remixes. Vince ends 2021 by presenting his label's biggest and most adventurous release to date, ‘DnA [re]Sequenced'. This is also accompanied by the [re]Sequenced Sampler which features 3 brand new mixes from the DnA album by Vince himself. The album also features some of electronic music titans including Carl Craig, Claude Young, Jon Dixon, Steve Rachmad, John Beltran, Shawn Rudiman, Stephen Lopkina and Stephen Brown. After the massive response to Watson's ‘DnA' album in 2019, Vince had wanted to carve a different spin on the LP by having some of the tracks remixed by his favourite Detroit ‘flavoured' artists from the three places that have influenced his music: Scotland, Amsterdam, Detroit. We premiere his track ‘First Wave [808 Mix]'. The track is reminiscent of some classic Galaxy 2 Galaxy records from Underground Resistance. A punchy but still funky 808 drum workout locks in the groove while angelic style synth work transcends you to space. Warm and fluffy pads simmer through the track while a powerful baseline runs through your body, the heavenly lead bounces around the track with an entrancing melody. The track is powerful, euphoric and tranquil all at the one time. This is proper electronic music. Vince Watson ------------------- SC: @vincewatson FB: www.facebook.com/vincewatsonmusic Four Four Magazine --------------------------- FB: www.facebook.com/FOURFOURDANCE/ IG: www.instagram.com/fourfourmagazine/ Web: www.fourfourmag.com/
Ready For Takeoff - Turn Your Aviation Passion Into A Career
An approach lighting system (ALS) is a lighting system installed on the approach end of an airport runway and consisting of a series of lightbars, strobe lights, or a combination of the two that extends outward from the runway end. ALS usually serves a runway that has an instrument approach procedure (IAP) associated with it and allows the pilot to visually identify the runway environment and align the aircraft with the runway upon arriving at a prescribed point on an approach. Modern approach lighting systems are highly complex in their design and significantly enhance the safety of aircraft operations, particularly in conditions of reduced visibility. The required minimum visibilities for instrument approaches is influenced by the presence and type of approach lighting system. In the U.S., a CAT I ILS approach without approach lights will have a minimum required visibility of 3/4 mile, or 4000 foot runway visual range. With a 1400-foot or longer approach light system, the minimum potential visibility might be reduced to 1/2 mile (2400 runway visual range), and the presence of touchdown zone and centerline lights with a suitable approach light system might further reduce the visibility to 3/8 mile (1800 feet runway visual range). The runway lighting is controlled by the air traffic control tower. At non-towered airports, pilot-controlled lighting may be installed that can be switched on by the pilot via radio. In both cases, the brightness of the lights can be adjusted for day and night operations. Depth perception is inoperative at the distances usually involved in flying aircraft, and so the position and distance of a runway with respect to an aircraft must be judged by a pilot using only two-dimensional cues such as perspective, as well as angular size and movement within the visual field. Approach lighting systems provide additional cues that bear a known relationship to the runway itself and help pilots to judge distance and alignment for landing. After World War II, the U.S. Navy and United Airlines worked together on various methods at the U.S. Navy's Landing Aids Experimental Station located at the Arcata–Eureka Airport, California air base, to allow aircraft to land safely at night and under zero visibility weather, whether it was rain or heavy fog. The predecessor of today's modern ALS while crude had the basics — a 3,500 foot visual approach of 38 towers, with 17 on each side, and atop each 75 foot high tower a 5000 watt natural gas light. After the U.S. Navy's development of the lighted towers it was not long before the natural gas lights were soon replaced by more efficient and brighter strobe lights, then called Strobeacon lights. The first large commercial airport to have installed a strobe light ALS visual approach path was New York City's John F. Kennedy International Airport. Soon other large airports had strobe light ALS systems installed. All approach lighting systems in the United States utilize a feature called a decision bar. Decision bars are always located 1000′ farther away from the threshold in the direction of the arriving aircraft, and serve as a visible horizon to ease the transition from instrument flight to visual flight. Approach lighting systems are designed to allow the pilot to quickly and positively identify visibility distances in Instrument meteorological conditions. For example, if the aircraft is at the middle marker, and the middle marker is located 3600 feet from the threshold, the decision bar is 2600 feet ahead. If the procedure calls for at least half a statute mile flight visibility (roughly 2600 feet), spotting the decision bar at the marker would indicate enough flight visibility to continue the procedure. In addition, the shorter bars before and after the decision bar are spaced either 100 feet or 200 feet apart, depending on the ALS type. The number of short bars the pilot can see can be used to determine flight visibility. Approaches with lower minimums use the more precise 100-foot spacing systems for more accurate identification of visibility. Several ALS configurations are recognized by the International Civil Aviation Organization (ICAO); however, non-standard ALS configurations are installed at some airports. Typically, approach lighting systems are of high-intensity. Many approach lighting systems are also complemented by various on-runway light systems, such as Runway end identifier lights (REIL), Touchdown Zone Lights (TDZL), and High Intensity Runway Lights (HIRL). The most common approach light system configurations include: MALSR: Medium-intensity Approach Lighting System with Runway Alignment Indicator Lights MALSF: Medium-intensity Approach Lighting System with Sequenced Flashing lights SALS: Short Approach Lighting System SSALS: Simplified Short Approach Lighting System SSALR: Simplified Short Approach Lighting System with Runway Alignment Indicator Lights SSALF: Simplified Short Approach Lighting System with Sequenced Flashing Lights ODALS: Omnidirectional Approach Lighting System ALSF-1: Approach Lighting System with Sequenced Flashing Lights configuration 1 ALSF-2: Approach Lighting System with Sequenced Flashing Lights configuration 2 CALVERT I/ICAO-1 HIALS: ICAO-compliant configuration 1 High Intensity Approach Lighting System CALVERT II/ICAO-2 HIALS: ICAO-compliant configuration 2 High Intensity Approach Lighting System LDIN: Lead-in lighting REIL: Runway End Identification Lights RAIL: Runway Alignment Indicator Lights In configurations that include sequenced flashing lights, the lights are typically strobes mounted in front of the runway on its extended centerline. These lights flash in sequence, usually at a speed of two consecutive sequences per second, beginning with the light most distant from the runway and ending at the Decision Bar. RAIL are similar to sequenced flashing lights, except that they end where the white approach light bars begin. Sequenced flashing lights and RAIL do not extend past the Decision Bar to avoid distracting the pilot during the critical phase of transitioning from instrument to visual flight. Sequenced flashing lights are sometimes colloquially called the rabbit or the running rabbit.
Strange symptoms with no clear cause. Medical histories that mystify even the most experienced doctors. Dr. Ian Krantz, Co-Director of CHOP’s Roberts Individualized Medical Genetics Center, specializes in solving “medical mysteries” – and he and his team have found answers for many patients who had almost given up hope. He joins Madeline to discuss the latest advances in precision medicine, why it’s important to share data with other scientists, and more.
This show features current trax from the UK Soul Chart, the Traxsource Soul, Funk & Disco Chart, and a selection of new and recent releases. Selected, Sequenced and Mixed by BrianG.
In this episode, I have a conversation with the author & collaborators of a newly released book titled "On the corners of Argyle and Glenwood which documents Khmer Refugees living in Uptown Chicago in the early 90s. As a young graduate student in photography in the early 1990s. Stuart Isett found himself on the corners of Argyle and Glenwood streets in Chicago, photographing Cambodian refugees who had settled on the city's north side near his apartment. Isett entered a world which would define his practice, spending much of the next 25 years working in South East Asia, often returning to work on issues affecting the Cambodian diaspora. Nearly 30 years later, in collaboration with Cambodian-American activist Silong Chhun and Pete Pin, a Cambodian-American photographer, Isett revisited the Chicago work. Together they re-sequenced and contextualised the series. Chhun and Pin would have been the young boys in the back of the room in many of Isett's images, watching their older siblings who were Isett's main focus, as they struggled to adapt to life in America while burdened with the trauma of war and genocide. Sequenced by Pin, with words from Chhun, this book explores the complexities of the early diaspora, not only the streets but also the tender moments of a community in transition, held together by family (“krousar”) and tradition. Source & book purchase link: https://www.catfish.asia/books/on-the-corners-of-argyle-and-glenwood --- Support this podcast: https://anchor.fm/chluytalk/support
The Lunar Saloon Every Friday from 10P - 12A PST 99.1 FM Long Beach Streaming at KLBP.org Air date : February 5, 2021 -=-=-=-=-=-=-=-=-=- E Ruscha V & Woo, Who Are You (Woo Dub), Woo Are You Peter Sands, Service Station, The Sound Of Action Egberto Gismonti, Noite Sem Fim, Cidade Coração Astral Sounds, Metropolis, Teletext Science, Look Don't Touch (Long Version), Look Don't Touch Laser, Galaxy, Laser Daniel Grau, Atlantis, Disco Fantasy The Bob Crewe Generation, Free (Medley) - I Am ... Free ... Keep On Walkin', Street Talk Shane Martin, I Need You, Northern Soul - Hall Of Fame Jerry Jones, Oh Me Oh My, Studio One Lovers Rock Leon Mitchison & The Eastex Freeway Band, Love Is, Soul Cal: Disco & Modern Soul 1971-1982 Midnight Runners, Tonight, Tugboat Edits Volume 14 Thunder, Speed Cross, Speed Cross Klaus Weiss, Course Race Track, Sport Sequences Vol. 2 Doctor's Cat, Theme From Rodeo, Gee Wiz The Voyagers, Distant Planet, Distant Planet Falco, Der Kommissar, Einzelhaft Kings Of Tomorrow Featuring April, Fall For You (Sandy Rivera's Classic Mix), DJ-Kicks: Moodymann Hiperboreal, Tijuana For Dummies, Nortec Collective - The Tijuana Sessions Vol.1 Subject, The Magic, The Moment (Momental Mix), The Magic, The Moment Autarkic, And The Tribe Debates.., Treble Rebel EP The Field, Sequenced, Yesterday and Today Curve, Super Blaster, Cuckoo Red Hot Chili Peppers, Search And Destroy, Give It Away The Pixies, Bagboy, Bagboy Men At Work, Crazy [Non LP B-Side], Business As Usual The New Year, My Bleeding Wound, Personal Space Electronic Soul 1974 - 1984
Meet Tarah Darge, a digital marketing native and Head of Marketing at timetoreply. She has a passion for start-ups and loves helping brands grow.In this episode, you'll hear how timetoreply was built from a sales conversion win, how to build a pipeline using sequenced messaging, the foundational metrics you can use for experiment baselines, and expanding on the traditional one-to-one demos with themed webinars. And finally, buying lessons from paid social ads. Enjoy!Notes:- 03:00 Giving The Ability To Measure And Report On Business Email Reply Times- 05:30 Research: Replies Timeframe Benchmark For Prime Close Rate- 06:55 Finding Product-Market Fit By Using Own Support Channel- 09:25 Coming In After Funding To Build Out The Marketing Plan And Team- 11:10 A Different Approach To Lead Gen Using LinkedIn- 13:45 Crafting The Initial Outreach Emails- 15:55 Real-Time Learning And Culling Campaigns Ruthlessly Following Benchmarks- 18:10 Webinars: Going Past The Usual One-On-One Demos- 19:40 Deciding To Do More Themed Webinars- 21:40 Using A Combination Of Tactics To Drive Webinar Registrations- 23:01 Experimenting With On-Demand Webinars- 24:00 Hard Lesson: The Need To Really Clarify Language Around The Product And Target- 27:15 Next: Growing The Partner Program And Continuing To Build Relationships- 29:40 The Challenge With Affiliate Marketing With A Low Price Point Product- 31:20 Lightning Questions
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.10.30.360610v1?rss=1 Authors: Ecovoiu, A. A., Ghita, I. C., Chifiriuc, D. I. M., Ghionoiu, I. C., Ciuca, A. M., Bologa, A. M., Ratiu, A. C. Abstract: Transposon annotation is a very dynamic field of genomics and various tools assigned to support this bioinformatics endeavor were reported. Genome ARTIST (GA) software was initially developed for mapping artificial transposons mobilized during insertional mutagenesis projects. Now, the new functions of GA_v2 qualify it as an effective companion for mapping and annotation of class II natural transposons in assembled genomes, contigs or sequencing reads. Tabular export of mapping and annotation data for subsequent high-throughput data analysis, the export of a list of flanking sequences around either the coordinates of insertion or around the target site duplications (TSDs) and generation of a consensus sequence for the respective flanking sequences are all key assets of GA_v2. Additionally, we developed two accompanying short scripts that enable the user to annotate transposons existent in assembled genomes and to use various annotation offered by FlyBase for Drosophila melanogaster genome. Herein, we present the applicability of GA_v2 for a preliminary annotation of the class II transposon P-element in the genome of D. melanogaster strain Horezu, Romania, which was sequenced with Nanopore technology in our laboratory. Our results point that GA_v2 is a reliable tool to be integrated in pipelines designed to perform transposon annotation in new sequenced genomes. GA_v2 is open source software compatible with Ubuntu, Mac OS and Windows and is available at https://github.com/genomeartist/genomeartist and at www.genomeartist.ro. Copy rights belong to original authors. Visit the link for more info
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.09.16.299594v1?rss=1 Authors: Hekel, R., Budis, J., Kucharik, M., Radvanszky, J., Szemes, T. Abstract: Introduction: Current and future applications of genomic data may raise ethical and privacy concerns. Processing and storing genomic data introduces a risk of abuse by a potential adversary since the human genome contains information about sensitive personal traits. For this reason, we developed a privacy preserving method, called Varlock, for secure storage and dissemination of sequenced genomic data. Materials and methods: The Varlock uses a set of population allele frequencies to mask personal alleles detected in genomic reads. Each detected allele is replaced by a randomly selected population allele concerning its frequency. Masked alleles are preserved in an encrypted confidential file that can be shared, in whole or in part, using public-key cryptography. Results: Our method masked personal variants and introduced new variants called on an individual's genome, while alternative alleles with lower population frequency were masked and introduced more often. We performed joint PCA analysis of personal and masked VCFs, showing that the VCFs between the two groups can not be trivially mapped. Moreover, the method is reversible; therefore, personal alleles can be unmasked in specific genomic regions on demand. Conclusion: Our method masks personal alleles within mapped reads while preserving valuable non-sensitive properties of sequenced DNA fragments for further research. Accordingly, masked reads can be stored publicly, since they are deprived of sensitive personal information. Personal alleles may be restored in arbitrary genomic regions for interested parties: patients, medical units, and researchers. Keywords: genome, privacy, personal data Copy rights belong to original authors. Visit the link for more info
After a special series about digital health in Asia and Africa covered in 2019, the upcoming four episodes will present speakers from South America. A shoutout goes to Unity Stoakes and Jennifer Hankin from Startup Health, which connected me to the speakers in the upcoming episodes. All the companies are StartupHealth Transformers. In this discussion, you will hear Adrian Turjanski, Chief Science Officer at Bitgenia - an Argentinian startup bringing genomics closer to society, explains the current state of genomics research in South America; he talked about the difference between the whole genome and exosome sequencing, and the use of AI in genetic sequencing. In the upcoming episodes, you will hear from Luis Santiago - CEO of the Venezuelan healthcare IT company PEGASI, Javier Cardona, the CEO of the Colombian telemedicine company 1Doc3, Paulo Fernando Buarque de Gusmão, CEO of Brazilian company OTAWA health. Digital Health in Asia Series: https://www.facesofdigitalhealth.com/blog/f041045-digital-health-in-asia-china-india-south-korea-and-singapore Digital Health in Africa Series: https://www.facesofdigitalhealth.com/blog/f056-f060-digital-health-in-africa-series-tanzania-nigeria-south-africa-rwanda
Today’s episode is about proof, identity and DNA. What are you looking for, when you look for your heritage? What can DNA really tell you? And who decides which forms of proof are required when? To answer this question, we spoke with Dr. Alondra Nelson, president of the Social Science Research Council and Harold F. Linder Professor at the Institute for Advanced Study and author of The Social Life of DNA: Race, Reparations, and Reconciliation After the Genome. The voices from our QVC nightmare future were provided by: Host 1 — Henry Alexander Kelly: Website, podcast La Lisa: A Latinx Podcast Host 2 — Ashley Kellem: Instagram, Website Darcy Noelle Apgar — Shara Kirby: Twitter To get even more, you can become a Flash Forward Presents Time Traveler for access to behind the scenes exclusive content, early access to new shows, and other surprises & goodies. 〰️〰️〰️ More information and show notes here 〰️〰️〰️ Advice For And From The Future is written, edited and performed by Rose Eveleth. The theme music is by Also, Also, Also. The logo is by Frank Okay. Additional music this episode provided by Blue Dot Sessions. To get even more, you can become a Flash Forward Presents Time Traveler for access to behind the scenes exclusive content, early access to new shows, and other surprises & goodies. Show Sponsors: Shaker & Spoon: A subscription cocktail service that helps you learn how to make hand-crafted cocktails right at home. Get $20 off your first box at shakerandspoon.com/futureadvice. Tab for a Cause: A browser extension that lets you raise money for charity while doing your thing online. Whenever you open a new tab, you’ll see a beautiful photo and a small ad. Part of that ad money goes toward a charity of your choice! Join team Advice For And From The future by signing up at tabforacause.org/futureadvice. Tavour: Tavour is THE app for fans of beer, craft brews, and trying new and exciting labels. You sign up in the app and can choose the beers you’re interested in (including two new ones DAILY) adding to your own personalized crate. Use code: futureadvice for $10 off after your first order of $25 or more. Purple Carrot: Purple Carrot is THE plant-based subscription meal kit that makes it easy to cook irresistible meals to fuel your body. Each week, choose from an expansive and delicious menu of dinners, lunches, breakfasts, and snacks! Get $30 off your first box by going to www.purplecarrot.com and entering code futureadvice at checkout today! Purple Carrot, the easiest way to eat more plants! Learn more about your ad choices. Visit megaphone.fm/adchoices
The genetic code for our most wanted pest, the stoat, has been revealed.
A selection of classic and contemporary tracks released under the Defected Label. Selected, Sequenced and Manually Mixed on Pioneer Decks by BrianG.
Today's Guest: Robert Green, MD | Director, G2P Research, Division of Genetics, Brigham & Women's Hospital | Founder, Genome Medical | Professor of Medicine (Genetics), Harvard Medical School Greg and Robert explode some of the persistent myths around genetic testing and dive in to the future of genetic testing amongst healthy populations Important Links: Robert's Bio: https://www.genomes2people.org/about/director/ Genomes2People: https://www.genomes2people.org/ Genome Medical: https://www.genomemedical.com/ Robert's LinkedIn: https://www.linkedin.com/in/robert-green-md-mph-54286135/ Robert's Twitter: https://twitter.com/RobertCGreen
Our Thought Leader is Ellie Moss, Lead for the new USFRA report, Navigating the Food Metrics Maze.•Productivity of Farms in the Heartland has Increased over time—except for the smallest Farms.• Scientists have now Sequenced the Avocado Genome...so what is the benefit?• An innovative Retailer has Quadrupled their Online Farmer Engagement.Today's farmer is Galen Lee, former USFRA Board member and farmer.
Since the human genome was first sequenced nearly 20 years ago, around a million people have had theirs decoded, giving us new insights into the links between genes, ancestry and disease. But most of the genomes studied have been in people of European descent. Now a decade-long collaboration between scientists in the UK and in Uganda has created the largest African genome dataset to date. Dr Deepti Gurdasani discusses her research with Gaia Vince. After 7 years of orbiting the Earth and sending us important information about space weather, NASA’s Van Allen Probes are retiring. Professor Lucie Green from UCL explains how the sun can spit out superhot plasma and streams of high energy particles in our direction. We are mostly protected by the Earth’s magnetic field - but not always. The worst-case scenario is that the radiation could disrupt navigation satellites and bring down electrical power supplies. Professor Green will be keeping an eye on space weather with a new spacecraft. Growing evidence shows that repeatedly getting your head knocked around during competitive sports can lead to long-term serious consequences. The head doesn’t necessarily need to be the target of the blow – a hard tackle can ricochet through your body giving your head a jolt. Roland Pease speaks with sports scientist Liz Williams of Swansea University about a new device to measure these impacts. Presenter: Gaia Vince Producers: Jen Whyntie and Louisa Field
Scientists, including from UC Davis, have successfully sequenced the coast redwood and giant sequoia genomes, completing the first major milestone of a five-year project to develop the tools necessary to study these forests’ genomic diversity. Over the past 150 years, 95 percent of the ancient coast redwood range and about one-third of the giant sequoia range have been logged. If diversity has declined, it could leave the redwoods vulnerable to drought, fire and other stressors related to climate change. Series: "UCTV Prime" [Science] [Show ID: 35170]
Scientists, including from UC Davis, have successfully sequenced the coast redwood and giant sequoia genomes, completing the first major milestone of a five-year project to develop the tools necessary to study these forests’ genomic diversity. Over the past 150 years, 95 percent of the ancient coast redwood range and about one-third of the giant sequoia range have been logged. If diversity has declined, it could leave the redwoods vulnerable to drought, fire and other stressors related to climate change. Series: "UCTV Prime" [Science] [Show ID: 35170]
Scientists, including from UC Davis, have successfully sequenced the coast redwood and giant sequoia genomes, completing the first major milestone of a five-year project to develop the tools necessary to study these forests’ genomic diversity. Over the past 150 years, 95 percent of the ancient coast redwood range and about one-third of the giant sequoia range have been logged. If diversity has declined, it could leave the redwoods vulnerable to drought, fire and other stressors related to climate change. Series: "UCTV Prime" [Show ID: 35170]
Project Radio Silence The album "Vibes - part - next" Tracklist : 01 - Every little bit 02 - Sequenced vibes phaze II 03 - Falling in green eyes 04 - Impression 05 - Rivers of oblivion 06 - Under weight of heavens 07 - Sequenced vibes phaze III ( The last gate ) 08 - Cloudmaker`s place 09 - Tales about cosmic outcomer 10 - The land where giants live 11 - Sequenced vibes phaze IV (Drive) 12 - Dive so slow 13 - Alice toys 14 - Disco throw 15 - Falling in green eyes - another version Release date : 2006 Alexey Markov - composer, arranger, performer, concept author Page composer Alexey Markov https://vk.com/id115071494 http://neane.ru/rus/3/member/markov.htm#discography --- Send in a voice message: https://anchor.fm/podcast-cd8c8e8/message
Scientists have sequenced the avocado genome and reviewed an incredible history including just how cloned these buttery fruits really are.
“Re-sequence your approach based on physiologic priorities” -Petro“Customize, then optimize” -ChrisATLS provides a useful and structured approach to the patient with multiple injuries. However, strict adherence to the ABCDE script can cause harm in certain circumstances. In this talk, Chris and Petro discuss how to customize resuscitation based on physiologic priorities. (18:36)
In this week’s episode, we give an update on our libraries being prepped and sequenced by NWGC: libraries accounting for sampling day and infection statuses. Additionally, we talk about the plan for when sequence data arrives in August/September.
We have the ability to sequence the DNA of every newborn, generating information that could help diagnose diseases and predict conditions that might have a later onset. But should we? In what contexts is sequencing helpful or harmful? On the latest Hastings Conversations podcast, Hastings Center President Mildred Solomon talks with Barbara Koenig, a Hastings Center fellow and director of bioethics at the University of California, San Francisco, about the findings of a major federally-funded research project convened by UCSF in collaboration with The Hastings Center. Koenig delves into the rationale behind the project’s recommendations that all newborns not be sequenced at this time. The findings appear in a recent special report on the ethics of sequencing newborns, published by The Hastings Center, available for free: https://onlinelibrary.wiley.com/toc/1552146x/2018/48/S2 Hastings podcasts like this one are supported by listeners like you. In fact, 45% of the work that we do is funded by individual donors. Visit us at thehastingscenter.org to contribute and learn more. Hastings Conversations explores critical questions in bioethics and cutting-edge research at The Hastings Center. Hosted by Hastings Center president Mildred Solomon.
In this episode, we talk about genetic sequencing and the negatives of it being sold. We explore what will happen if corporations or individuals have this information. Follow us on Social Media: @RDRSHOWDUO --- Support this podcast: https://anchor.fm/the-rdr-show/support
On this episode of Sequenced, Dr. Ranjit Manchandra, Clinical Senior Lecturer at Barts Cancer Institute in London, sits down with Business Insider’s Erin Brodwin to discuss population-based genetic testing for cancer prevention. Dr. Manchandra’s recent research found that population testing for multiple breast cancer genes has the potential to be both cost-effective and life-saving.
On this episode of Sequenced, Halle Tecco, founder of Rock Health and Angel Investor at Techammer, sits down with Business Insider’s Lydia Ramsey to discuss the digital health landscape, the recent JP Morgan, Amazon, and Berkshire Hathaway news, and achieving gender parity in healthcare.
Loving someone with cumulative and complex relational injuries can be challenging. Learn to manage the impacted neurobiology and relational wounds. This episode addresses both children and adults with complicated attachment histories and gives ideas about how to manage. Whether it’s your own history or someone you love, let’s be honest – it can be challenging at times to be in very close relationships when early attachment injuries have been layered and ongoing and unaddressed. Threat and unrepaired relational ruptures are encoded in our biology and our neurological systems. Child and Family Therapist Robyn Gobbel, LCSW joins co-host Sue Marriott LCSW, CGP for a discussion on complex trauma and the importance of boundaries and depersonalizing, especially as a parent. You’ll learn how to best communicate between your partner and child when things get tense and how best to employ structured nurture and scaffolding in those relationships. Robyn Gobbel – Robyn is the founder of Central Texas Attachment & Trauma Center and specializes in adoption, attachment, and trauma. She leads webinars for parents and clinicians and will be releasing a new podcast soon! Stay tuned! Related episodes: Episode 23 (https://www.therapistuncensored.com/self-compassion-dr-kristin-neff/) and Episode 51 (https://www.therapistuncensored.com/tu-51/) n 0:00-15:00 Introduction Defining “trauma” and the difficulties in doing so Neurobiology of trauma Complex Trauma Trauma in relationships Gobbel’s interest in trauma Gobbel’s focus on working with children, starting early when individual is in safe family space and setting groundwork for the future 15:00-30:00 Listener question about multigenerational trauma Self-compassion, acknowledging complex history Importance of being able to look back and repair rather than aim to be perfect all the time What happens when one parent/partner is regulated and the other isn’t. If intervention is necessary make sure it’s about compassion rather than accusing the partner of messing up. What Gobbel has learned from working with parents, children and families: When curiosity and compassion open up, ability to repair greatly increases Steve Finn and moving from shame to guilt; shame is inherent in complex trauma Structured Nurture and finding the right balance 30:00-45:00 Importance of ability to depersonalize, particularly as a parent, in order to have delight around your children Understanding and how to best employ “scaffolding” in yourself and with your children Wrap Up Resources It’s Not You But What Happened to You (http://amzn.to/2mDQjJ7) by Chrisitine Courtois Treating Complex Trauma a Sequenced Relationship-based Approach (http://amzn.to/2D9Ok65) By Christine Courtois Julian Ford Creative Therapies for Complex Trauma Helping Children and Families in Foster Care, Kinship Care or Adoption (http://amzn.to/2DcEKPQ) Edited by Joy Hasler and Anthea Hendry Contact Robyn: http://centraltexasattachmenttrauma.com/ (http://centraltexasattachmenttrauma.com/) https://www.gobbelcounseling.com/ (https://www.gobbelcounseling.com/) Tweet (https://twitter.com/intent/tweet?url=https%3A%2F%2Fwww.therapistuncensored.com%2Ftu53%2F&via=austinshrinks) Support this podcast
On this episode of Sequenced, we talk to Katherine Wilemon, founder and CEO of the FH Foundation, and Dr. Jill Hagenkord, Color’s Chief Medical Officer, about Familial Hypercholesterolemia (FH), an inherited high cholesterol disorder. Katherine and Dr. Hagenkord discuss what differentiates FH from garden variety high cholesterol, why FH is underdiagnosed in the U.S., and how an FH diagnosis can impact an individual’s family members. The FH Foundation is a patient-centered nonprofit organization dedicated to research, advocacy, and education of Familial Hypercholesterolemia (FH). Their mission is to raise awareness and save lives by increasing the rate of early diagnosis and encouraging proactive treatment.
On this special episode of Sequenced, Dr. Brawley and Dr. Len, Chief Medical Officer and Deputy Chief Medical Officer, of the American Cancer Society join us to discuss the newsworthiness of cancer research, cancer prevention strategies, and the future of healthcare. Our moderator is Leena Rao a technology reporter based in San Francisco. The American Cancer Society is committed to freeing the world from cancer and is focused on cancer research, sharing expert perspectives, and increasing awareness for cancer prevention.
On this episode of Sequenced, we talk to Lindsay Avner, Founder and CEO of Bright Pink, about her journey as a BRCA mutation carrier, why she founded Bright Pink, and how women can be advocates for their own health.
On this episode of Sequenced, Vinod Khosla, renowned Silicon Valley entrepreneur and investor, sits down with CNBC’s Chrissy Farr to discuss how technology will reinvent healthcare as we know it.
House & Techno Mixed Set. Sequenced and compiled by DJ Weeksey. Expect to hear tracks by Reset Robot, Roni Size, Majesty, A Lister, Pirupa plus many more. Enjoy
We’ve heard on the program over the past few years that genomic medicine will probably take off first in a country with a centralized health service. And when the U.K. announced their 100K Genomes Project at the end of 2012 with the creation of Genomics England in 2013, it was certainly a bold visionary move to do just that—to put the entire country on a progressive path toward precision medicine for all. So with 10K genomes sequenced, how is the project going?
House & Techno Mix. Compiled & Sequenced by DJ Weeksey You can expect to hear tracks by Ron Costa, Reset Robot, Hot since 82, Joeski, Volkoder plus many more. Enjoy
Across all age ranges, U.S. adults said that they preferred companies to contact them via email as opposed to any other medium (according to a 2015 MarketingSherpa survey). However, that does not necessarily mean customers are anxiously awaiting your sends. With customers' inboxes being flooded daily with ads and newsletters, they carefully skim the subject lines, searching for easy emails to eliminate. In this Web clinic replay, the research team shares three observations on crafting effective subject lines gleaned from two tests, including an experiment which resulted in a 26% increase in clickthrough rate.
Actually there was no news this week. It turns out the whole industry took the week off to watch the stunning Ken Burns documentary on cancer. No, that’s not true. We did find some news. How about this? The Affordable Care Act turned five this past week. Happy Birthday, ObamaCare! So we thought we’d share some important numbers about the ACA: 11.7 million: the number of Americans who have signed up for 2015 coverage. 46%: the increase in enrollment from 2014 to 2015.
An unreleased track from the summer of 2013. Entire mix is Produced, Sequenced, Engineered by DJ Moleculez. Support The Movement! Continuous Play duration: 9:11 Mins. ENJOY!
Entire mix was Produced, Sequenced, Engineered by DJ Moleculez. Thank you to all the artists that participated in this project & for the continued support. Support The Movement!
Please join us for this very special episode of Canadian Musician Radio, dedicated to the one and only Bruce Cockburn. A Canadian songwriting icon, Cockburn has just released his brand new limited edition box set, Rumours of Glory. Sequenced as a companion piece to his published memoirs, this limited edition 9-disc set includes 16 rare and previously unreleased songs along with Bruce’s first live DVD. It includes 117 songs, a previously unreleased live concert DVD filmed during three shows in 2008, and a 90+-page book featuring rare photos, extensive track information, and liner notes by Nicholas Jennings. We'll speak with the artist himself about his longevity in the industry, his approach to writing now as compared to that of his formative years, and a lot more. ALSO, as an Exclusive Offer for Canadian Musician fans, use the discount code CM15 and get 15 per cent off the Rumours of Glory Limited Edition Box Set by visiting: http://bit.ly/1wzwGzU.
What is genome sequencing? How is it different from other kinds of genetic testing? And what can it really tell you about your health? Wendy Kohlmann, a genetic counselor at the Huntsman Cancer Institute at the University of Utah, answers these questions and explains who should get it done, and where the technology is heading.
You might have seen: Yahoo! News, Unraveling the Bonobo's Genome, and its Secrets, June 13, 2012; http://news.yahoo.com/unraveling-bonobos-genome-secrets-172659659.html
Posted in BlogPodcast Play Audio Joe shares a great letter sequence for collecting money The story and strategy behind a $3,000,000 letter sequence The most profitable thing to do when you find an ad that works PLUS: When to stop mailing a profitable letter or postcard Download MP3 | Transcript
Transcript -- Ms Abi Bouwman reports on the results of the Rivenhall women's DNA tests.
Ms Abi Bouwman reports on the results of the Rivenhall women's DNA tests.
Ms Abi Bouwman reports on the results of the Rivenhall women's DNA tests.
Transcript -- Ms Abi Bouwman reports on the results of the Rivenhall women's DNA tests.
Music for Alterd States Of MindSequenced-mixed-produced by 18111-Silent Intelligence (Part II) - Original Mix - Richie Hawtin, Pete Namlook - Minus2-Spank! It Up - Original Mix - Christian Quast - Futureaudio3-Close My Eyes - Original Mix - Obando - Attari4-Evolve - Original Mix Prompt - 7Noise5-Out - Original Mix - Ellen Allien - Bpitch Control6-Mellow Dee - Original Mix - Ricardo Villalobos, Jay Haze - Contexterrior7-Vacaciones En Chile - Original Mix - Ilario Alicante - Tenax8-A Black Man In Space - Bonus Beats - Son Of Raw - Objectivity9-Lalaland - Original Mix - Rohrer, Siegel - Supdub Digitales10-Kaiserdisco - Remix by Kaiser Souzai & Nudisco -Swoosh - Yellow Tall11-Jackpot - Original Mix - Marco Carola - Plus 812-Varese Ist Leer - MiniCoolBoyz Remix - Marco Dassi - Supdub Digitales13-Mirage - Publicmind Remix - James Marshall - Groovin'HighPODCAST HERESoldiers of the undergrounds MUSIC FOR ALTERED STATES OF MIND
Sequenced-mixed-produced by 18111 - Sunday afternoon 25.8 in the centre of Helsinki (Finland) by Kamppi metro-station 2 - The Rabbit - Goblin - Cinevox3 - Ghost_Story 4 - Gwarek2 - Aphex Twin - Rhino/London-Sire5 - Snowflake - Trentemøller - Poker Flat 6 - Gwely mernans - Aphex Twin - Rhino/London-Sire7 - Mellow Dee - Ricardo Villalobos, Jay Haze Drum Story - Steve Reid Ensemble - Soul Jazz8 - Andruic and Japan - Andrew Gillings/Ricardo Villalobos9 - Migracion (Ricardo Villalobos Remix) - Lopazz - Contexterrior10 -Primer Encuentro Latino-Americano - Ricardo Villalobos11 -I Want To Sleep - DJ Koze - IRR12 -Bell Song from Lakme- Maria Callas, Delibes PODCAST HERESoldiers of the undergrounds MUSIC FOR ALTERED STATES OF MIND
Music for Altered States of MindSequenced, Mixed and produced by 18111-Windowsill - Aphex Twin - Warp2-The White Flash feat. Thom Yorke - Modeselektor - BPitch Control3-Fresas Y Anchoas - Emie - Sirius Pandi4-El Baile Del Enano Jardin - Monoblock - Immigrant5-Migracion - Ricardo Villalobos Remix - Lopazz - Get Physical6-The Cat - Canvas - Rebelone7-Reflections in Plexiglass - Phunklarique, Dejonka - Knall Traxx8-Albertino - Guido Schneider, Andre Galluzzi - Cadenza9-Obsure - Seph, Pablo Denegri - Dumb Unit10-Mederico - Guillaume, The Coutu Dumonts - Oslo11-Mode - Original Mix - G. Riedatz - Timbee12-Mono Turn - Broombeck - Big City BeatsPodcast hereSoldiers of the undergrounds MUSIC FOR ALTERED STATES OF MIND
Music for Altered States of MindSequenced, Mixed and produced by 18111-Intro/Lexicon - Kruder & Dorfmeister - !k72-One Of These Days - Pink Floyd live in Venice 15- 7 -89 - Bootleg3-Chameleon - Trentemøller - Poker Flat4-Whenever - Dolly Laparton -Bemysheep5-Martian Keg Party - Army Of One - Exun6-You Got Good Ash [Gabriel Ananda Remix] - Marek Bois - Trapez7-Nakuta - Timo Anttila - Frozen North8-To The Gum - Riton Vs. Heidi - Get Physical9-Escarabajos - Ernie - Signs of Authority10-Dragon (Shit Robot Remix) - Dondolo - Tiny Sticks11-Deep Throat - Claude VonStroke - Dirty Bird Records12-Cretine - Paco Osuna - Plus 813-Newbe [Heartthrob's Are U Gay Remix] - Dario Zenker - Esperanza14-Freefall - Tiefschwarz - 64 Records15-Release - Mario Fabriani - Nightshift16-Release (Louie Vega Mix) - Ursula Rucker - Slip N SlidePODCAST HERESoldiers of the undergrounds MUSIC FOR ALTERED STATES OF MIND
A selection of Irish electronica from the late 90s to today. Sequenced in Ableton by droid + slug for the 'Underground' Exhibition 27/06/08 - 06/07/08 in Road Records, Dublin.