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Neil Koenig, ex BBC producer and current ideaXme board advisor and guest interviewer, interviews Mohammed Afkhami, philanthropist and art collector. If asked to name a country associated with modern art, few people today might think of Iran. The collector Mohammed Afkhami is working hard to change that perception. In this age that we are in now anything that promotes misunderstood or unknown cultures is a plus. In recent years he has amassed a large collection of Iranian art. Mr Afkhami says his love of art began at an early age: “we used to visit my grandfather's house multiple times a week, and he collected Islamic art and antiquities, Western artworks, Japanese lacquer…it was a fascinating and enchanting house of treasures”. He left Iran as a young child, after the revolution at the end of the 1970s. After embarking on a successful career in finance, he eventually returned in the early 2000s. “It felt like coming home” he explains. Mohammed Afkhami was surprised and delighted by the quality of contemporary art available, even though there were only a small number of galleries open at the time in Tehran. He bought works by Sirak Melkonian and Massoud Arabshahi for around $500 apiece. Since then, the collection has grown to include works by artists such as Shirin Neshat, Monir Farmanfarmaian, Parviz Tanavoli, Abbas Kiarostami and many more. What is the art scene like in Iran today? According to Mr Afkhami it is thriving, despite the impact of sanctions. There are now hundreds of galleries in Tehran, he says: “an artist is lucky to have a show that lasts longer than a month, because there's such a backlog of artists wanting to exhibit”. In an interview with me for ideaXme, Mohammed Afkhami talks about his passion for his country's art, how he built his collection and how he works with artists and galleries, and how art can serve to broaden understanding and break down cultural barriers. “Rebel, Jester, Mystic, Poet: Contemporary Persians—The Mohammed Afkhami Collection”, can be seen at the Asia Society in New York until May 2022. Drawing from the collection of financier and philanthropist Mohammed Afkhami, the exhibition comprises paintings, sculptures, photographs, and videos. Of the 23 participating artists, over a third live in Iran, over a third live outside of Iran, and five live in New York City. These established, mid-career, and emerging artists are working from unique vantage points, informed by a rich cultural heritage as well as more recent extensive social and political unrest in Iran. Referencing “contemporary Persians,” the exhibition's title evokes an ancient culture that is still very much alive today. The curator of the exhibition is Dr. Fereshteh Daftari. Neil: https://www.linkedin.com/in/neilkoenig/ https://twitter.com/neilkoenig?lang=en ideaXme is a global network - podcast on 12 platforms, 40 countries, mentor programme and creator series. More soon. Get involved: https://radioideaxme.com/get-involved/ Mission: Move the human story forward™
10.10.2021 | Jerrod Brooks
Andrea Macdonald, founder of ideaXme interviews Sir John Hegarty. Sir John Hegarty, co-founder of global advertising and communications company BBH (Bartle Bogle Hegarty) and founder of The Garage Soho, Investment Company is one of the world’s most awarded and respected creatives in history. He has written 2 best-selling books with a possible third in the pipeline. Current books, Creativity: There Are No Rules and Advertising: Turning Intelligence into Magic have not just been benchmarks for both the creative and communications industries, they have inspired disruptors and innovators working across a myriad of seemingly unrelated sectors. At the heart of Hegarty’s work, his creativity, business ethos and indeed his philosophy of life stands one word. That word is “truth”. Listen to this ideaXme interview or read the transcript of the interview below to learn of how truth and creativity combined has rocketed Sir John Hegarty to the top of the creative world. "The foundation of any long-term relationship is probably two things, love and truth. You can't have love without truth. So, truth comes first. What you're trying to do is constantly build the truth." Sir John Hegarty, ideaXme interview. For the full transcript visit www.radioideaxme.com Sir John Hegarty’s Career: Hegarty has been at the forefront of the global creative advertising industry for over 50 years, from the early days of Saatchi and Saatchi to Bartle Bogle Hegarty, which was founded in 1982 and sold to Publicis in 2012. In 2014, building on this legacy, Hegarty founded The Garage Soho, an investment company with creativity at its heart. “Sometimes marketing is not enough. You need to change the product”. Sir John Hegarty, ideaXme interview The Garage Soho: The Garage Soho is an early stage investor and brand builder. They invest between £100K - £500K into companies' pre-series A with a focus on technology enabled consumer brands. The team work closely with portfolio companies on their brand strategy, creative and media partnerships from the outset and throughout their journey to exit. Companies are chosen on the basis of “their potential to change the world”. Bartle Bogle Hegarty: Sir John Hegarty founded Bartle Bogle Hegarty with John Bartle and Nigel Bogle. The agency soon became one of the most famous and awarded advertising agencies in the world. Today, BBH’s 7 offices worldwide include London, New York, Singapore, Sao Paulo, Shanghai and Mumbai. John, was responsible for campaigns for Levi’s such as the ground-breaking commercial starring an unknown model called Nick Kamen who stripped off down to his boxer shorts in a launderette. As a bi-product sales of boxer shorts went through the roof. He created the tagline 'Vorsprung Durch Technik' for Audi and picked Brad Pitt to star in a commercial for Levi’s. He pioneered the importance of music in commercials, earning BBH nine number 1 hits. John also oversaw the first viral phenomenon to hit the headlines, the furry yellow puppet Flat Eric for Levi’s, who kicked Eminem off the number 1 singles slot in 1999. "You never really leave BBH" Sir John Hegarty comments on his departure from BBH in 2012, ideaXme interview Awards: In 2007 he was Knighted in the Queen’s birthday honours. John has also won numerous golds awards at D&AD, Cannes and British Television. He has been bestowed with the D&AD President's Award for outstanding achievement and was admitted to the US One Show Advertising Hall of Fame. Hegarty sits on the Board of Trustees of the Design Museum. In this interview: John answers questions from: -Simon Anholt, author, researcher, policy advisor and global intellectual and Alan Firmin, founder and CEO of Tribal Heart, who spent 20 years as a creative director at FCB, Y&R and VML and more recently as a lecturer at University of London. John talks of: His career, philosophy and business ethos as well as the importance of creativity as a force for good. Potential of "truth" to transform not just creativity but the world. His application of "the truth", from his creative work to managing his vineyard in France. What he would like you to see. Where companies should start with Corporate Social Responsibility. Why he'd like you to watch The Romantics tv series His trust in ideas. The one global challenge that he would like to address with his creative power. Interview credits: Andrea Macdonald, founder ideaXme. ideaXme is a global podcast, creator series and mentor programme. Mission: Move the human story forward™. Find ideaXme on all major podcast platforms. Connect on Twitter @ideaxm on Instagram @ideaxme
Are you looking to get into cycling? Join us for a great conversation in this episode about the importance of finding community, how to get started in cycling and doing it the right way, how to cross train and effectively prevent common cycling injuries and so much more in this episode.If you want to get a hold of Joel, you can find him at www.missionmovept.com or contact him on Instagram at @missionmovept , @thecyclingpt or join his No Drop Cycling Group on Facebook or send him an email at info@missionmovept.com. If you enjoyed this show, make sure to subscribe and please help us by leaving a 5 star review. Also, don’t hesitate to reach out on social media @iostrengthperformance, or better yet - tag me in a post with your favorite part of the show! Most men have lost their physical and mental edge that is keeping them from living out their full potential, so we’ve created a way to help you get your edge back. Join the Men Made for More Facebook group (https://www.facebook.com/groups/MenMadeForMore/) to learn how to strengthen your body, your mind, and your purpose to become the man you know you can be.
Andrea Macdonald, founder of ideaXme interviews Kazuhiro Gomi (Gomi-san), M.S., CEO and President of NTT Research. Discover how this exciting Silicon Valley start-up plans to upgrade reality. NTT (Nippon Telegraph and Telephone Corporation) Global: NTT Global, the parent company of NTT Research, is a top 5 global technology and business solutions provider with operations in 80 countries worldwide. They service 85% of Fortune Global 100 companies and consider themselves as a big contributor to society by applying "technology for good". Their services include digital business consulting, technology and managed services for cybersecurity, applications, workplace, cloud, data centre and networks. Kazuhiro Gomi: Gomi-san has worked at NTT for over 20 years, holds an undergraduate degree in Industrial Engineering and two M.S. degrees - in both Industrial and Electrical Engineering. Currently, Kazuhiro Gomi is CEO and President of NTT Research, a Silicon Valley start-up. Within just a year of its foundation NTT Research has revealed a number of exciting projects including Digital Twins, a platform which focuses in the first instance on reflecting a twin of the human cardio system to predict, manage and optimise individuals' cardio health. Longterm objectives are broader - to combine digital information which reflect the real world to synthesise diverse virtual worlds, generate novel services and "to upgrade reality". Kazuhiro Gomi's career to date: 2019: President and CEO. NTT Research. 2012: Board of directors, NTT Communications Corp. 2010: President and Chief Executive Officer, NTT America, Inc. 2009: COO, NTT America, Inc. 2004: VP of Global IP Network Business Unit, NTT America, Inc. 2001: VP of Global Business Department, NTT Communications Corp. 1998: Director of General planning, NTT Cyber Communications Laboratory Group. About NTT Research and their Mission to "Upgrade Reality": NTT Research launched in July 2019, comes from a rich lineage of ground-breaking research and development. The NTT Research and Development Lab in Tokyo, Japan boasts over 1600 patents. NTT Research currently hosts 3 Labs - Phi, MEI and CIS Labs all of which collaborate with leading universities working at the forefront of technology. Although most collaborations are with US Universities, there are plans to reach out to collaborate across the world. NTT Research Phi Lab: The Phi Lab's mission is to build simple, efficient and practical solvers for real-world problems in human's information-intensive society. Their objective is to rethink “computation” within the fundamental principles of quantum physics and brain science and to develop hardware and software simultaneously. NTT Research MEI Lab: MEI Lab is dedicated to the medical and health sciences as they relate to Digital Twin Computing (DTC), part of the IOWN initiative. For on-the-ground medical experimentation, DTC is an ideal application. Imagine administering a treatment to one’s digital twin (alter ego) in the cyber world. If the treatment does not work, doctors can move on quickly to a different approach without risk to their human patient. NTT Research CIS Lab: The Cryptography and Information Security (CIS) Laboratories focusing on technologies and initiatives which include securing people's data. The CIS Lab is led by NTT Fellow Tatsuaki Okamoto. Its goals is to become the leading cryptography research laboratory in the world. They explore attribute-based encryption, homomorphic encryption, and functional encryption regarding security and privacy. They utilise quantum computing and blockchain keeping an open mind as to the technologies that deliver trust and security for all users in the future. ideaXme interview with Kazuhiro Gomi: In this interview Gomi-san discusses the successes of the past year at NTT Research. His upcoming plans for the exciting NTT Silicon Valley start up. He talks of NTT's Digital Twin and NTT Global's IOWN projects, his approach to managing NTT Research and supporting some of the world's most brilliant technologists the opportunity to do work that has the potential to "upgrade reality". Credits: Andrea Macdonald interview and text. ideaXme is a global podcast, creator series and mentor programme. Mission: Move the human story forward™. Visit our website: www.radioideaxme.com Find ideaXme on all major podcast platforms. Connect on Twitter @ideaxm on Instagram @ideaxme
Dr. Shima Beigi, Founder of Mindfulness Engineering™️ BSc,MSc,MSc,Ph.D. Resilience Scientist, Author, Yogi and ideaXme Rich Connectedness™️ ambassador interviews Francis Heylighen, Cyberneticist and Research Professor at the Free University of Brussels where he directs the trans-disciplinary research group on "Evolution, Complexity and Cognition" and the Global Brain Institute. Francis Paul Heylighen (born 1960) is a Belgian cyberneticist investigating the emergence and evolution of intelligent organization. He presently works as a research professor at the Vrije Universiteit Brussel (the Dutch-speaking Free University of Brussels), where he directs the trans-disciplinary research group on "Evolution, Complexity and Cognition" and the Global Brain Institute. He is best known for his work on the Principia Cybernetica Project, his model of the Internet as a global brain, and his contributions to the theories of memetics and self-organization. He is also known, albeit to a lesser extent, for his work on gifted people and their problems. Dr Shima Beigi comments: In this new episode of ideaxme Rich Connectedness™️ Podcast series, I, Dr. Shima Beigi founder of Mindfulness Engineering™️ and ideaxme Rich Connectedness connect with Professor Francis Heylighen, a Belgian cybernéticien and complexity scientist at the Dutch speaking University of Brussels (VUB). http://pespmc1.vub.ac.be/HEYL.html Apart from being my mentor and colleague for the past 6 years, Professor Heylighen’s expansive publications have been a source of inspiration for many complexity scientists around the world. https://scholar.google.com/citations?hl=en&user=jt7BHBUAAAAJ&view_op=list_works&pagesize=100 Due to the ongoing challenge of COVID-19, similar to my other podcasts, I decided to focus this discussion on the subject of complexity and how it can provide a more interdisciplinary approach to the challenge of recovering from the coronavirus pandemic. Over the past decade, the science of complexity has began to attract the attention of many prominent thinkers, businesses, scientists, and scholars. The main reason for this keen interest stems from the overwhelming evidences that classical Newtonian view of the world is very limited in its capacity to solve complex and wicked problems. Complex and wicked problems refer to those challenges that the cause and effect of events are not linear meaning the cause and effect an event can not be traced back to a single trajectory of event(s). These systems follow exhibit what’s called nonlinear behaviours. Non linear behaviours makes predictions extremely difficult if not impossible. In such a system, long term planning if not impossible. This in itself provides another challenge for control and managent. Today, as COVID-19 continues to spread around the world, these unpredictability and uncertainty are even more tangible. But, what if we view these events from the perspective of a complexity scientist and cybernéticien? In this conversation, Professor Heylighen provides his point of view on our current times, offers his model of buffer challenge landscape which is inspired by the principle of Ashby Law of Requisite Variety. https://www.academia.edu/22638152/Cybernetic_principles_of_aging_and_rejuvenation_the_buffering-_challenging_strategy_for_life_extension According this law, only systems that are capable of abdicating the diverse range of perturbations that enter into their inner boundaries are able to adapt and continue to evolve. I discuss these with Professor Heylighen and explore how we can integrate some of these cybernetic principles into our systems at both individual and collective levels. What makes a system resilient isn’t the planning per se, but its cognitive capacity to expect the unexpected. To join this discussion, make sure you follow our platform on YouTube. To submit your questions or request for an interview in the Rich Connectedness™ series, and to watch live interviews please connect with me on my instagram platform @dr.shima.beigi or my Twitter @MindfulnessEngi and subscribe to our platform on YouTube. Dr. Shima Beigi BSc, MSc, MSc, PhD. Founder of Mindfulness Engineering™ Resilience Scientist, Smart City Expert, Consciousness Coach Fully Certified EMCC Leadership and Mindfulness Coach Yoga Alliance Registered Yoga Instructor Ambassador for Rich Connectedness™ at ideaxme Platform Author of Mindful Smart City Manifesto: Rethinking Smart Cities with Mindfulness Engineering™ Author of God Molecule Coming Soon 2020 Mindfulness Engineering™: Unlocking Resilience Potential in People and Places Globally™ ideaXme is a global podcast, creator series and mentor programme. Mission: Move the human story forward!™ ideaXme Ltd.
Dr Shima Beigi, Founder of Mindfulness Engineering™️ BSc,MSc,MSc,Ph.D. resilience scientist and ideaXme Rich Connectedness™️ ambassador interviews Gregg Braden, five-time New York Times best-selling author, scientist, international educator and renowned pioneer in the emerging paradigm based in science, spirituality, social policy and human potential. Dr Beigi comments: The COVID-19, the disease caused by the novel coronavirus has laid bare deep insecurities and vulnerabilities of our world from political domain to food security to mental health and to many more. The pandemic has also put humanity in a collective state of uncertainty. How will life change after the coronavirus? How can we build a more resilient world? What will happen to millions of enterprises that have been forced to close down? Will we recover from this global health crisis? Will a new outbreak emerge when the lockdown is lifted? These are some of the many pressing questions that no one really has an answer for, at least for the time being. Nevertheless, there are important facts that we need to recollect. Humanity is resilient. Looking at the history of human development, there are many inspiring takes of triumph. We must revisit them. While the COVID-19 is taking our built systems to the edge of their capacity to respond, equally, it is pushing our minds to the edge of what it is naturally meant to do: imagination. In this special episode of ideaXme Rich Connectedness Podcast, I, Dr. Shima Beigi, founder of Mindfulness Engineering™️ and Rich connectedness ambassador explore ways to navigate the uncertainty caused by COVID-19 with Gregg Braden. Gregg Braden is a five-time New York Times best-selling author, researcher, educator, lecturer and internationally renowned as a pioneer bridging modern science, spirituality, and human potential. From 1979 to 1991 Gregg worked as a problem solver during times of crisis for Fortune 500 companies, including Cisco Systems where he became the first Technical Operations Manager in 1991. He continues problem-solving today as he merges modern science and the wisdom of our past to reveal real-world solutions to the issues that challenge our lives. His research has led to 15 film credits and 12 award-winning books now published in over 40 languages. Gregg is a member of the American Association for the Advancement of Science (AAAS) and is active with visionary organizations including the HeartMath Global Coherence Initiative and The Arlington Institute. He has presented his discoveries in over 30 countries on six continents and has been invited to speak to The United Nations, Fortune 500 companies and the U. S. military. The United Kingdom’s Watkins Journal lists Gregg among the top 100 of “the world’s most spiritually influential living people” for the 6th consecutive year, and he is a 2020 nominee for the prestigious Templeton Award, established to honor“ outstanding individuals who have devoted their talents to expanding our vision of human purpose and ultimate reality. ideaXme is a global podcast, creator series and mentor programme. Mission: Move the human story forward!™️ ideaXme Ltd.
Current movie "Dark Waters", directed by Todd Haynes and starring Anne Hathaway, Mark Ruffalo, Tim Robbins and Bill Pullman is based on the work of Robert Bilott environmental lawyer and author and, inspired by article "The Lawyer who became DuPont's Worst Nightmare" by Nathaniel Rich, New York Times Magazine (credited by Mark Ruffalo as being inspiration for movie). https://www.nytimes.com/2016/01/10/magazine/the-lawyer-who-became-duponts-worst-nightmare.html ideaXme spoke with Robert Bilott this week to hear of the movie, Robert's book "Exposure" https://www.amazon.com/Exposure-Be-Confirmed/dp/1501172816 and his ongoing work to raise public awareness of PFOA, a chemical (used in many products including Teflon) which "poisons the world's drinking water". Listen to Robert's story of how he exposed the dark waters of a chemical company (DuPont and Chemours, Teflon moved from DuPont to Chemours during the legal process) and made them pay $670.7 million in settlement. Moreover, discover how he is expanding his work across the USA and the world to bring the chemical companies to justice. What can you do to help? Robert asks you to learn of this chemical and lobby your local politicians and agencies to join his campaign to clean-up the world's water! Andrea Macdonald, founder of ideaXme, interviews Robert Bilott, environmental attorney and partner at Taft Stettinius and Hollister LLP and author. Andrea Macdonald Comments: When you think of environmental justice, many hot-button issues spring to mind, such as climate change, global warming, and pollution. What we don't, unfortunately, hear enough about, are the people fighting for justice behind the scenes in an attempt to hold large corporations accountable for present, as well as past actions. Today, I had the pleasure of speaking to one of the world's leading environmental attorneys, whose inspiring career of exposing some of the world's largest chemical companies and seeking justice for those affected has now been adapted into an award-winning feature film. Robert Bilott, Environmental Attorney and Author: Robert Bilott received his law degree from The Ohio State University College of Law, going on to specialise in environmental law, primarily for corporations, at Taft Stettinius & Hollister LLP, where he has been a partner since 1998. That same year, he was contacted by a farmer in West Virginia, setting him off on a 22-year long journey which continues on to this day. Farmer Wilbur Earl Tennant contacted Bilott, looking for answers as to why his cows, alongside other local animals, were becoming ill and dying. He suspected a nearby landfill was the cause, due to a mysterious white foam contaminating a creek from which the animals drank. PFOA Chemical: Testing revealed that the water was being contaminated by Perfluorooctanoic Acid, referred to as PFOA and C-8, which is used to make Teflon. Further research uncovered a number of harrowing facts: PFOA was cancerous, and had been contaminating the community's drinking water for decades. Exposure of One of World's Largest Chemical Companies: Robert Bilott is also the author of the book Exposure, which chronicles his fight for environmental justice against DuPont. Exposure has now been adapted into the feature film Dark Waters, directed by Todd Haynes and starring Mark Ruffalo, Anne Hathaway, Tim Robbins, and Bill Pullman. Robert Bilott has received numerous awards throughout his career, including the Right Livelihood Award, which he received for his work exposing a decades-long history of chemical pollution, winning long-sought justice for the victims, and setting a precedent for effective regulation of hazardous substances. Read the full interview transcript on ideaXme's website:www.radioideaxme.com. Listen to the interview across all major podcasting platforms. Movie release information: https://www.imdb.com/title/tt9071322/releaseinfo What you need to know about PFOA: https://www.theguardian.com/us-news/2019/may/23/pfas-everyday-products-toxics-guide ideaXme is a global podcast, creator series and mentor programme. Mission: Move the human story forward!™ ideaXme Ltd. Follow Robert Bilott on Twitter @RobertBilott Dark Waters on Twitter @DarkWatersMovie Mark Ruffalo on Twitter @MarkRuffalo ideaXme on Twitter @ideaxm and on Instagram @ideaxme
Karen Potter, director of Sustainability Hub and ideaXme sustainability ambassador interviews Paula Owen, Ph.D., Founder and CEO of Green Gumption and Director and Chief Fun Officer at Eco Action Games. Paula is a climate change scientist. She is a UK based specialist in energy, carbon and climate change with experience in building and delivering advisory and training services to the public and private sector. Owen is author of many publications explaining the link between energy, carbon and climate change. She is creator of games to aid behaviour change. Moreover, became a GLA/London SDC London Leader in summer 2012. She is an accomplished media spokesperson with 10 years experience, a regular on Radio 4's 'You & Yours'. Paula set up her own company in 2010 to work with government departments, charities, national and international NGOs and businesses to help them improve their environmental performances and train staff. Her clients include: DECC, Defra, OFGEM, Big Lottery Fund, Tate Galleries, Bank of America Merrill Lynch, Ernst & Young (now EY); EU Commission, EU.BAC, CLASP, Energy UK and Energy Saving Trust. Eco action games, an education environmental games company, was set up in 2013. It concentrates on the invention and production of simple, social games with environmental messaging that enhances societal awareness of environmental issues and promotes personal action. She is also an author and has published a book on 'How gamification can help your business engage in sustainability' in 2013 - available from Do Sustainability publishers. Paula's charity work includes acting as member of the board of Trustees for charity 10:10, now Possible. Karen is a passionate project development specialist with extensive experience in designing and delivering new initiatives to promote sustainability, social responsibility, smart energy, green economy and clean tech investment. Owen is highly experienced in government, NGO and public sector communications, building and managing senior stakeholder relations and media engagement. In this interview Paula shares: How she came to study climate change chemistry. How she came to study information science and why. Whom she would like to meet on her death bed. Her expertise to make climate change facts "real" for the general public. Who has influenced her most in moving both her career and human story forward. How she came to work with this person. What makes her chief influencer special. How covid-19 will change the aviation industry, possibly to make it more sustainable. Global air emissions - ground source level and higher carbon dioxide emission (planetary). That she is interested to see post covid-19, as a comparison, the reduction in deaths due to decreased emissions (people not travelling) and deaths due to covid-19. Interview credits: Karen Potter, ideaXme sustainability ambassador. Please note Karen Potter is now director of Sustainability Hub and not project director. This interview is available in audio format across 11 further platforms. Here www.radioideaxme.com, iTunes, Stitcher, Spotify and more. ideaXme is a global podcast, creator series and mentor programme. Mission: Move the human story forward!™ ideaXme Ltd.
Dr Shima Beigi, Founder of Mindfulness Engineering™ BSc, MSc, MSc, Ph.D. interviews Harry Halpin, CEO Nym Technologies SA to talk of the threats and opportunities of hyper-digital connection in the time Covid-19. Harry Halpin: Harry Halpin's goal is to halt surveillance and fight for human freedom through decentralization. 'The terrain of struggle' is technology. Privacy-enhancing technologies and cryptography are his 'weapons'. The article which accompanies this interview will be available here shortly: www.radioideaxme.com Nym Technologies comment: "Data harvesting has dominated Silicon Valley business models over the past decade and has rapidly become the norm for monetizing online activity. Understanding and predicting user behaviour is now core to both old and new media businesses, for example, from the Financial Times to Facebook, who famously sold its users out to its commercial clients like Cambridge Analytica. These data-driven models, collectively known as surveillance capitalism, have produced giant tech monopolies that oversee an unprecedented system of control. Governments, meanwhile, are fighting to preserve centralized power and manage polarized populations by heavily censoring and controlling the internet, fragmenting it even further. In this climate, the prospect of having any privacy online is disintegrating. It is important to realize just how lacking current technology is with regards to maintaining privacy. A private messenger like Signal might encrypt a message’s contents, but metadata identifying the timing, sender and receiver is accessible by powerful third parties that monitor the internet and can readily identify users. In this world of big data, this information is in many ways more valuable than the contents of messages — it can be used by sophisticated and ubiquitous analytic systems to determine the nature of your social relationships and thus predict your personal characteristics and preferences. The necessary technology to guarantee online privacy has remained underdeveloped until now for reasons related to limitations in computing, networking, research and funding. We believe that it is now possible to overcome these limits and deploy technology that provides strong privacy guarantees, avoids trusted third parties, and is resistant to surveillance. How Nym can make the internet private: Nym itself is neutral to the technology interfacing with it, providing an open-ended anonymous overlay network that works to irreversibly disguise patterns in internet traffic. The more activity on the network, the more private it becomes — and so users have safety in numbers, just like in the real world. Nym improves on existing alternatives via mix-networking. The Sphinx packet format renders all data packets a uniform size, the traffic is mixed probabilistically with timing obfuscation, cover traffic is added, and multiple hops ensure users do not have to trust a single node. This mixing defeats the kinds of traffic-analysis attacks that can deanonymize packets on VPNs, Tor and I2P. In addition, Nym uses blockchain technology to decentralize the operations of the mixnet so that the network has no centralized points of failure. A major obstacle for any decentralized network is assembling real-world resources to run nodes. Tor and I2P’s volunteer model works but has limitations. With the logistical complexity of finding trusted and reliable volunteers, global reach is difficult: volunteers tend to be centralized in wealthy Western countries, with the majority of Tor relays in places like Germany and the US. We think incentives can fix this problem. Nym uses anonymous authentication credentials based on the Coconut signature scheme to enable privacy-enhanced data transfer and decentralized identity. Nym credentials can embed the data needed for a given service (including zero-knowledge proofs of private data), and these credentials are validated in a decentralized and public manner without linking a user to the service they want to access. And importantly, Nym is sustainable because it uses incentives to decentralize and maintain the quality of service of the network. Inspired by Bitcoin, Nym’s breakthrough proof-of-stake system rewards nodes for mixing traffic rather than solving arbitrary merkle puzzles. Instead of a proof-of-work system, Nym node operators are rewarded for proof of mixing, ensuring privacy for all." Source Nym website ideaXme is a global podcast, mentor programme and creator series. Mission: Move the human story forward!™ ideaXme Ltd. Find ideaXme interviews across the internet in both video, text and audio format. Follow us on Twitter @ideaxm on Instagram @ideaxme
Ira Pastor, ideaXme life sciences ambassador and founder of Bioquark, interviews Dr. Derek Yach, founder, president, and board member of The Foundation for a Smoke-Free World, and passionate advocate for health promotion and disease prevention. Dr Yach's objective is to end smoking in this generation. We investigated to see how that might be achieved. Ira Pastor Comments: The World Health Organization (WHO) estimates that we currently have over 1.1 billion smokers on earth, and that tobacco kills more than 8 million people each year. More than 7 million of those deaths are the result of direct tobacco use while around 1.2 million are the result of non-smokers being exposed to second-hand smoke. The U.S. Centers for Disease Control (CDC) say that cigarette smoking is responsible for more than 480,000 deaths per year in the United States, including more than 41,000 deaths resulting from secondhand smoke exposure. This is about one in five deaths annually, or 1,300 deaths every day. Smoking leads to disease and disability and harms nearly every organ of the body. More than 16 million Americans are living with a disease caused by smoking including cancer, heart disease, stroke, lung diseases, diabetes, and chronic obstructive pulmonary disease (COPD), which includes emphysema and chronic bronchitis, as well as increasing risk for tuberculosis, certain eye diseases, auto- immune disorders including rheumatoid arthritis, and erectile dysfunction in males. Total economic cost of smoking in the U.S. alone is more than $300 billion a year, including nearly $170 billion in direct medical care for adults and more than $156 billion in lost productivity due to premature death and exposure to secondhand smoke. Ending Smoking for Good The Foundation for a Smoke-Free World (FSFW) is an independent, nonprofit organization that funds research, promotes innovation, and supports collaborative initiatives committed to reducing deaths and diseases caused by smoking, and ending smoking in this generation. They strive to identify and address the unique needs of the developing world as they relate to tobacco cessation and harm reduction, and serve as a convener of global research supporting the reduction of tobacco use, while helping to address the impact of decreased smoking rates on agriculture and economies. The Foundation’s work focuses on three core areas: Health, Science, and Technology (HST); Agriculture and Livelihoods; and Industry Transformation. Dr. Derek Yach Has Forged a Career Around Anti-Smoking Advocacy Dr. Derek Yach has been a global health expert and anti-smoking advocate for more than 30 years, and is also a passionate advocate for health promotion and disease prevention. Dr. Yach is a former World Health Organization (WHO) cabinet director and executive director for noncommunicable diseases and mental health where he was deeply involved with the development of the world’s treaty on tobacco control, the Framework Convention on Tobacco Control (FCTC). He is also the former chief health officer of the Vitality Group, executive director of the Vitality Institute, Senior Vice President, global health and agriculture policy at PepsiCo, director of global health at the Rockefeller Foundation, and a professor of global health at Yale University. He has authored or co-authored more than 250 peer-reviewed articles on global health and has served on several advisory boards, including the World Economic Forum, Cornerstone Capital, and the Wellcome Trust. Dr. Yach is a dual citizen of the United States and South Africa. He has an honorary DSc from Georgetown University, Bachelor of Medicine and Surgery from the University of Cape Town, BSc (Epidemiology), University of Stellenbosch, and an MPH from the Johns Hopkins Bloomberg School of Public Health. Disclosure: The Foundation for a Smoke-Free World has received its initial funding pledge of $80 million USD annually for 12 years, beginning in 2018 from Philip Morris International (PMI) - The Foundation has a nonprofit status as a US 501c3 organization, and by law and policy must operate completely independently from PMI, and cannot engage in activities designed to support PMI’s interests. Further, PMI can have no involvement or say in their work. On this episode we will talk to Dr. Yach about: His Background and how he developed an interest in medicine, public health, and smoking cessation. The Philip Morris International's funding of FSFW. About FSFWs Global State of Smoking Poll, Health, Science, and Technology programs, Agricultural Transformation Initiative and Industry Transformation efforts. Finally, we’ll hear about Dr. Yach's views on the dangers/health issues related to marijuana smoking. ideaXme is a global podcast, creator series and mentor programme. Mission: Move the human story forward!™ ideaXme Ltd.
Ira Pastor, ideaXme exponential health ambassador, interviews Dr. Ellen de Brabander, Senior Vice President Research and Development at PepsiCo. Ira Pastor Comments: Today we are going to segue into the food industry, which is a fascinatingly complex and diverse set of businesses that supplies most of the food consumed by the global population. In 2020, food, needless to say, is much more than just calories. It is, of course, still about about calories, but food is also about nutrition, health and wellness (and in some cases medicine), agriculture, sustainability, and even national safety and security. Today we are joined by a wonderful guest that we are going to discuss a wide range of these and related topics with. Dr. Ellen de Brabander: Dr. Ellen de Brabander is Senior Vice President Research and Development at PepsiCo (the American multinational food, snack, and beverage company), and currently leads the global R&D functions including the Food Safety, Quality, External Innovation, Strategy & Portfolio Management, Nutrition Science, Sensory and Regulatory Affairs teams. She is also a member of the Board of Governors at the New York Academy of Sciencesand has served as Treasurer and board member of the International Life Science Institute of North America which is US-Canadian organization that brings together scientists from government, academia and industry to uphold the scientific integrity and objectivity of nutrition and food safety science in order to ethically improve food systems for the betterment of public health. Additionally, Dr. de Brabander has also served as the interim and founding CEO of EIT Food (part of the EU’s European Institute of Innovation and Technology), which is a unique $1.5 Billion Euro innovation consortium with more than 50 partners from industry and academia, focused on transforming the food sector by designing and delivering unique and high impact research, innovation, business creation and education programs. Dr. de Brabander has worked in a variety of industries, including pharmaceuticals, health/nutrition, coatings and chemicals. Dr. Ellen de Brabander's Career Prior to joining PepsiCo, she was the Chief Scientific Officer and Global Head of Research, Development and Regulatory Affairs for Merial Limited (currently part of Boehringer Ingelheim), where she led a global team to discover and develop innovative animal health products for companion and production animals. Prior to her role at Merial, she held executive R&D, regulatory, business strategy and program management positions at Intervet (currently Merck animal health division) and the specialty chemical company DSM. Dr. de Brabander earned her PhD cum laude in bio-organic chemistry from Leiden University in The Netherlands and completed post-doctoral work in molecular biology at MIT with Nobel Laureate H.G. Khorana. Her PhD has been awarded as best PhD for natural sciences from Leiden University (1990; Kock award); in 2000, she was awarded the Golden Medal from the Royal Dutch Chemical Society for being the best Dutch chemist under 40 years of age. On this show we will hear from Dr. de Brabander: About her background, how she became interested in science, chemistry and biology, and ultimately how she worked her way into the leadership roles of some of the world's largest chemical, pharma, and food companies. Her view of the food industry today, it's future, and many of the parallels she sees with big pharma (personalization, customization, and specialty indications versus blockbusters) as well as the importance of data management and of the startup innovator as a partner. Her thoughts on "big food" as a major player alongside "big pharma" in the health and wellness equation moving forward in the 21st century. About her work in building / leading EIT Food, and ILSI North America, and the importance of the public-private partnership model in the $8 trillion food industry. Big Food's role in the sustainability equation as it pertains to feeding a future world of 9-10 billion. Her role and the importance of the compliance function in industries that are taking on more regulatory burdens. Credits: Ira Pastor interview video, text, and audio. Follow Ira Pastor on Twitter:@IraSamuelPastor ideaXme is a global podcast, creator series and mentor programme. Mission: Move the human story forward!™ ideaXme Ltd. Our objective is to encourage everyone to participate in the ideas that shape our world. Visit ideaXme's website: www.radioideaxme.com Follow ideaXme on Twitter:@ideaxm On Instagram:@ideaxme Find ideaXme across the internet including on iTunes, SoundCloud, Radio Public,TuneIn Radio, I Heart Radio, Google Podcasts, YouTube, Spotify and more. ideaXme is a global podcast, creator series and mentor programme. Our mission: Move the human story forward!™ ideaXme Ltd.
Andrea Macdonald, founder of ideaXme, interviews Mayor Zarifa Ghafari, first female mayor of Maidan Shahr, capital city of a province in Afghanistan and voted as one of the BBC 100 Women of 2019. Andrea Macdonald comments: The current war in Afghanistan began with the United States invasion on the 7th October 2001. It has cost the USA1 trillion dollars and the world, including Afghanistan, over 150,000 lives. The Washington Post’s ‘Afghanistan Papers’ is the latest contribution to a growing argument over whether the conflict, or any of the ‘forever wars’, was worth the cost. Mayor Zarifa Ghafari: Here, we talk to Mayor Zarifa Ghafari, a brave woman who argues for continued international presence in "Afghanistan's international war" and states how at both a local and international level we can all make a difference. Only 26 years old, Mayor Zarifa Ghafari has an MA in Economics from the University of Punjab and has had to fight for everything that she has achieved. As well as carrying out her role as the first female mayor of Maidan Shahr, capital city of a province in Afghanistan, she is the founder of Peghla radio stationand of NGO "APAW" Assistance and Promotion of Afghan Women. In this ideaXme interview we talk of the daily challenges that both she and her country face. Awaiting her assassination: Mayor Zarifa Ghafari told the New York Times in October 2019 that she awaits her assassination.Threats to her security are centred on the work she carries out as a female mayor in a war-zone. She remains adamant: "I am in love with my job!". Ghafari took up her position as first female mayor of Maidan Shahr, capital of Maidan Wardak province Afghanistan, 10 months ago. She explains to ideaXme why the Afghanistan war is an international war that requires a continued international presence in Afghanistan. She talks of her work to promote women's rights and education, the numerous projects for which she has been responsible in her 10 months so far as mayor. Ghafari also talks of her journey to becoming mayor and the hurdles she faced in taking up the position. Moreover, she explains why she urgently needs security assistance to continue the work she does. Below, read part of interview transcript. The full transcript www.radioideaxme.com includes details of who Mayor Zafari would like to meet as well as who has helped her the most to carry out her work and further her career. Moving the human story forward in Afghanistan and the world. Andrea Macdonald, founder ideaXme: Hello. Who are you? Zarifa Ghafari, Mayor of Maidan Shahr, Afghanistan: This is Zarifa Ghafari from Afghanistan, mayor of the Wardak Province. Working in a war zone: Andrea Macdonald, founder ideaXme: Your job is extremely dangerous. It is necessary as a woman, as anyone, to be very brave to do what you do. Could you talk about your job? Zarifa Ghafari, Mayor of Maidan Shahr, Afghanistan: My job is full of problems for me but it's interesting, amazing and I love it because I am the first female mayor for my province of Wardak. It is still not safe. It is a war zone province. I am a female mayor of a province where women don’t have rights. Most women are still deprived of education rights and humanitarian rights. Even walking outside is difficult. Zarifa Ghafari, Mayor of Maidan Shahr, Afghanistan: I am the mayor of a province where people still don't believe women should take part in society. So, I’m really proud of my job but it’s not safe. It is really dangerous and full of problems - social, political, cultural and security problems. But I’m really proud of my job. I roam around the city and get involved with a big group of men who are not so pleased to have a female mayor. I'm in love with my job. Andrea Macdonald, founder ideaXme: You were appointed in 2018, but you weren't allowed to take up the role immediately. Can you talk about that? The right to do my job as Mayor of Wardak: Zarifa Ghafari, Mayor of Maidan Shahr, Afghanistan: Yes, for nine months I wasn't allowed to join my office. It was really tough and full of problems. I went through a competitive process; I have a degree. But some groups of men, the land mafia and two people involved with the government were making problems for me because they didn’t want to accept a female mayor. I never lost my hope. I just kept fighting for it and went through a long process of waiting. Finally, after nine months it was over, and I became a part of my office. It was great. For the full transcript please visit www.radioideaxme.com. ideaXme is a global podcast also on 10 audio platforms. You can also find this interview in video format on our YouTube channel. Follow ideaXme on Twitter @ideaxm and on Instagram @ideaxme. ideaXme is a global movement to inspire universal curiosity and participation in the ideas that shape our world. Mission: Move the human story forward!™
Ira Pastor, ideaXme exponential health ambassador, interviews Dr. William Haseltine, American biologist, entrepreneur and philanthropist, known for his groundbreaking work on HIV/AIDS and the human genome. https://www.amazon.com/Aging-Well-Solutions-Pressing-Challenges/dp/9811321639 Ira Pastor Comments: On today's show we have a thought leader who sits amongst a rare group of people who have been responsible for creating many aspects of the modern biopharma / genomics / regenerative medicine system as we know it today. Dr. William Haseltine: Routinely listed in major media sources as one of the world's most influential business people and most influential leaders in biotechnology, Dr. William Haseltine is an American biologist, entrepreneur and philanthropist, known for his groundbreaking work on HIV/AIDS and the human genome. Dr. Haseltine earned a PhD in Biophysics at Harvard University, where he worked under the direction of Dr. James Watson, co-discoverer of the structure of DNA, and Dr. Walter Gilbert, Nobel prize winner for developing DNA sequencing techniques. Dr. Haseltine was also a post-doctoral fellow in the laboratory of Dr. David Baltimore at MIT, where he worked on fundamental aspects of reproduction of retroviruses that are known to cause cancer in animals. Dr. Haseltine's Career He served for many years as a professor at Boston’s Dana Farber Cancer Institute, Harvard Medical School, and the Harvard School of Public Health. During his time at Harvard Medical School, he founded two major research departments working on both cancer and HIV/AIDS, as well as became a founder of several biotechnology companies including Cambridge Biosciences, The Virus Research Institute, ProScript, LeukoSite, Dendreon, Diversa, X-VAX, and Demetrix. In addition to all of that, he became extremely well known in the world of bio-pharma for his leadership as CEO of Human Genome Sciences (HGS), a company that truly pioneered the application of genomics to drug discovery. He is currently the president of the Haseltine Foundation for Science and the Arts, and is the founder, chairman, and president of ACCESS Health International, a not-for-profit organization dedicated to improving access to high quality health worldwide. Dr. Haseltine is the author of many books including: Modern Aging: A Practical Guide for Developers, Entrepreneurs, and Startups in the Silver Market; Aging with Dignity; Voices in Dementia Care; and Aging Well. On today's show we will hear from Dr. Haseltine: About his background and how he developed an interest in science, biology, and how after an amazing career in biopharma / genomics / regenerative medicine, why he is now so passionate about this new triad encompassing aging, dementia, and healthcare quality / outcomes. His history of ushering in the genomics era in big pharma. About his model of "Value-Based Care" essential for creating better health outcomes for older patients. His principle of “Optimal Aging” which is not just about health status, but about elderly people being able to live active, engaged, and productive lives. His learnings in regard to best practices in dementia care, observed around the globe, that should be adapted and adopted by healthcare systems, healthcare providers, and those loving and caring for a person with dementia. Credits: Ira Pastor interview video, text, and audio. Follow Ira Pastor on Twitter:@IraSamuelPastor If you liked this interview, be sure to check out ourinterview with Dr. Victor Dzau, President of the United States National Academy of Medicine and of the United States National Academy of Sciences! Follow ideaXme on Twitter:@ideaxm On Instagram:@ideaxme Find ideaXme across the internet including oniTunes,SoundCloud,Radio Public,TuneIn Radio,I Heart Radio, Google Podcasts, Spotify and more. ideaXme is a global podcast, creator series and mentor programme. Mission: Move the human story forward!™ ideaXme Ltd.
Ira Pastor, ideaXme exponential health ambassador, interviews Ms. Nemonte Nenquimo, President of the Waorani Pastaza Organization (CONCONAWEP - Coordinating Council of the Waorani Nationality of Ecuador). This is an English language voice over of Ms Nenquimo's audio interview. Ira comments: Today we have a fascinating guest joining us on the ideaXme show from a rather remote location, to discuss ethnomedicine, environmental conservation and protection, entheogens (the topic of bio-active plant substances for spiritual and religious practices), as well as the themes of bravery and perseverance. Who Are the Waorani? The Waorani (Huaorani) People, are a group of native Amerindians from the Amazonian Region of Ecuador. They comprise almost 4,000 inhabitants and primarily speak the Waorani language, a linguistic isolate that is not known to be related to any other language. Their ancestral lands are located between the Curaray and Napo rivers, about 50 miles (80 km) south of the city of El Coca. These homelands—approximately 120 miles wide by 100 miles (from north to south) – are extensively threatened by oil exploration and illegal logging practices. Over the last 40 years, the Waorani have shifted from a hunting and gathering society to live mostly in permanent forest settlements. However, an estimated five communities have rejected all contact with the outside world and continue to move into more isolated areas. The first “outsider” encounter of the Waorani was with American missionaries back in the 1950s. Culturally, the Waorani take a traditional “animist” worldview, where there is no distinction between the physical and spiritual worlds, and spirits are present throughout the world. As the Waorani once believed that the entire world was the forest (and used the same word for both), the rainforest remains the essential basis of their physical and cultural survival, and they have remarkably detailed knowledge of its geography and ecology. Hunting supplies a major part of the Waorani diet and is of cultural significance. Before a hunting or fishing party ensues, the community shaman will often pray for a day to ensure its success. While a joyful activity, hunting (even permitted animals) has ethical ramifications to the Waorani. To counterbalance the offense of hunting, they use the muscle relaxant poison, curare, in blow darts. Hunting with such darts is not considered killing, but "retrieving," similar to a process of say harvesting fruits from the trees. Plants, especially trees, continue to hold an important interest for the Waorani. Their store of botanical knowledge is extensive, ranging from knowledge of building and crafting materials, to poisons, to hallucinogens, to medicines. Significant trees for the Waorani include the peach palm (used for making spears and blowguns, as well as for its fruit), as well as fast-growing balsa wood, used for ceremonial purposes. The Waorani incorporate shamanic ethno-medicine using both the plant based hallucinogenic beverage Ayahuasca (discussed in detail on a previous episode with Dr. Dennis McKenna), as well as various forms of medicinal mushrooms with psilocybin type compounds. Ms. Nemonte Nenquimois President of the Waorani Pastaza Organization(CONCONAWEP - Coordinating Council of the Waorani Nationality of Ecuador) whose focus is coordinating 12 different Waorani communities with a single voice to defend their territories. The Waorani view themselves as the true ancestral guardians of the jungle. Ms. Nenquimo attended Colegio Nacional Mixto Waorani. Ms. Nenquimo and CONCONAWEP were at the centre of a recent landmark legal victory against the Ecuadorian government leading to a half-million acres of Amazon rainforest protected from oil drilling and timber companies. Ms. Nenquimo does not speak English, so we have created an English voice over of her translated answers to my questions. On This Show We Will Hear from Ms. Nenquimo: About Ms. Nenquimo's background and how she became a leader of the Waorani people. We'll hear about the Waorani people and the various tribal groups that are currently part of it. She'll detail the importance of the Amazon rainforest to meet the food needs of the Waorani, as well as the importance of the Amazon rainforest to meet the natural medicine needs of the Waorani people. The importance of the Amazon rainforest in spiritual ceremonies for the Waorani people. Finally, we'll learn about the recent struggles and legal victories against the Ecuadorian government in protecting Waorani territories from oil and timber companies. For the transcript of this interview please visit www.radiodideaxme.com. ideaXme is a global podcast, creator series and mentor programme. Mission: Move the human story forward!™ ideaXme Ltd.
Andrea Macdonald, founder ideaXme Ltd. interviews Richard Whitehead, MBE, world record breaker and multi gold medallist in the T42 100m and 200m. A multi discipline athlete, Richard is also a world record breaker in the half and full marathon within the category for athletes with a double amputation (marathon record was beaten by Marko Cheseto at the 2019 Boston Marathon). Moreover, recently he is gold and silver medallist in T61 200m events. Please find the full transcript with photo's and links to this interview here shortly https://radioideaxme.com/interviews/ Here, Richard talks of his life growing up with a disability, career as a world class athlete who runs with Össur prosthetic legs and broader objectives to inspire people with his story and promote diversity and equality across society. He also talks of his official removal from the T42 100m event in 2017 after the last Paralympics which took place in Rio, effectively removing his chances of winning another medal at the Tokyo 2020 Paralympics. Richard Whitehead’s early aspirations: “I was shy and very quiet as a child. All my grandmother wanted for me was that I learn to drive and get a girlfriend” Richard Whitehead, MBE, the “Usain Bolt of the Paralympics”. Richard Whitehead commenting on his success: “They always list the materialistic honours. Whether that’s gold medals at the Paralympics at London 2012 or Rio, world titles or the MBE that I received from Prince Charles in 2012. I think that those things are very nice and a lot of them are great for the family but for me, I’d say I’m not governed by that success. Yes, it gives me a great platform to open up conversations, but I’m successful because I’ve worked hard, been dedicated and disciplined. I’ve had people around me that have given me the guidance and the opportunity to be the best that I ever could be”. Commenting on his change of classification from T42 to T61: “So, it can be quite frustrating as an athlete having to change. I started as a marathon runner and then had to change to 200 meters because I didn’t have a long-distance event. To run in the Rio 2016 Paralympic Games and get the gold in the 200 meters and the silver in the 100 meters and then to have the event cut is obviously quite frustrating. Not just for myself, but also for the legacy that you leave for other athletes. It’s really important that when you’re competing that you’re not just competing for yourself but for the sustained impact that your event has on the next generation of athletes”. Growing up with a disability: Richard grew up in Nottingham, UK, overcoming challenges of a double through the knee congenital amputation to reach the top of his sport worldwide. Since childhood, Richard has taken part in a broad range of sports. He was a swimming teacher before competing for Team GB as an ice sledge hockey player at the 2006 Winter Paralympics in Turin and then transitioned into running but even then, he did not stick to one event! Amongst Richard's many achievements: He broke the world record at the 2010 Chicago Marathon, completing his run in two hours and 42 seconds. He has completed 40 marathons in 40 days. He won the gold medal in the 200m at the London 2012 Paralympics, defended his title in the 200 T42 and won gold at the Rio Paralympics 2016. Furthermore, he claimed gold at the 2017 IPC World Championships and Silver at the World Para Championships 2019 in Dubai, relinquishing his Gold medal to Ntando Mahlangu, 17-year-old South African who claimed gold. Richard's broader purpose: Richard would like to be known for more than his achievements as an elite athlete. He is very active on the keynote speech circuit inspiring people with his “human story”, is an outspoken “athlete’s voice” who promotes, diversity and equality and works with many charities both as a fund raiser and ambassador. In memory of his friend Simon Mellows and inspired by amputee Terry Fox, Richard ran 40 marathons in 40 days, from completing over 900 miles to raise money for Sarcoma UK and Scope charities. Richard has worked with charities Meningitis Trust and Autism Awareness as well as helping amputees injured as a result of the Syrian Civil War in Jordan with humanitarian group Médecins Sans Frontier (MSF). This interview with Richard Whitehead MBE is one of the first of ideaXme's Tokyo 2020 playlist. We'll be interviewing the elite athletes and stakeholders in the games leading to the Tokyo 2020 Olympics and Paralympics. Follow ideaXme's Tokyo 2020 playlist. You can also watch the Tokyo 2020 interviews in video format on ideaXme's YouTube channel. Credits: Filming by Alan Johnson and Parth Kakkar MetFilm School. Follow us on Twitter @ideaxm on Instagram @ideaxme. ideaXme is a global podcast, creator series and mentor programme. Mission: Move the human story forward!™ ideaXme Ltd.
"When I was born the doctor wanted to kill me!", Ali Jawad. Jawad, is a paralympic gold medalist and world record breaking powerlifter with Crohn's disease. He has had to overcome many challenges in life. His motto: "Why be the best when you can be the greatest?". Ali's competition personal best is 195kg but in the gym he has bench pressed over 200kg. Ali Jawad, born as a double above the knee amputee, is a full time athlete, currently competing at 54kg in the qualifying rounds (final round end of April 2020) to participate in the Tokyo 2020 Paralympics. Although, Ali is one of the highest performing powerlifters in the world he can be taken down by Crohn's disease at any time. Ali took up powerlifting at the age of 16. He competed in the 2012 Summer Paralympics in London, finishing fourth. The following year he took gold at the Asian Open Championships making a world record lift of 185.5 kg. He gained a world title at the 2014 World Championships in Dubai, won the European title and gold at the 2015 Americas Open Championships and at the 2016 Rio Games, Ali won silver and his first ever Paralympic medal for lifting 190kg. More recently he claimed silver at the Tokyo 2019 World Para Powerlifting World Cup at the Tokyo 2020 test event. He is famous across social media for his celebratory competition dances, some of which have "gone viral". Revealed in this interview, a new dance is planned for Tokyo 2020. Despite the pressure of living with Crohn's disease, performing as an elite athlete with high levels of pain and challenges to control that discomfort, Ali is an anti- doping advocate and educator sitting on the UK Athletes Anti Doping Commission Board. He is one of the highest profile commentators in the athlete movement to ban doping. This interview includes Ali's comments relating to the World Anti Doping Agency (WADA) ruling on 9 December 2019 which bans Russia from competing at Tokyo 2020. ideaXme was the first organisation to catch Ali for his reaction to ruling. WADA ruling: On 9 December, the World Anti-Doping Agency’s Executive Committee (ExCo) endorsed the recommendation made by the independent Compliance Review Committee (CRC) that the Russian Anti-Doping Agency (RUSADA) be declared non-compliant with the World Anti-Doping Code (Code) for a period of four years. Meeting in Lausanne, Switzerland, the 12-member ExCo supported the CRC’s recommendation, which includes a series of strong consequences and conditions of reinstatement in accordance with the International Standard for Code Compliance by Signatories (ISCCS). The Chair of the CRC, Jonathan Taylor QC, took ExCo members through the CRC’s recommendation, which had been provided to ExCo members on 25 November together with the report of WADA Intelligence and Investigations (I&I) and that of the independent forensic experts from Lausanne University’s Institute of Forensic Science. “For too long, Russian doping has detracted from clean sport. The blatant breach by the Russian authorities of RUSADA’s reinstatement conditions, approved by the ExCo in September 2018, demanded a robust response. That is exactly what has been delivered today. Russia was afforded every opportunity to get its house in order and re-join the global anti-doping community for the good of its athletes and of the integrity of sport, but it chose instead to continue in its stance of deception and denial. As a result, the WADA ExCo has responded in the strongest possible terms, while protecting the rights of Russian athletes that can prove that they were not involved and did not benefit from these fraudulent acts". WADA Since the interview, WADA received the resignation of Victoria Aggar, a highly respected member of its own Athlete Committee, who said she was standing down after WADA broke its promises and failed to protect clean athletes. Demand for The Paralympics 2020: When it comes to tickets, next year’s Tokyo Paralympics will be just like the Olympics. International Paralympic President Andrew Parsons announced on Tuesday this week that there were 3.1 million tickets requested earlier this year in the first lottery phase. This exceeds the 2.3 million available. About 600,000 tickets were awarded in the first lottery, and another lottery is set for early next year. Follow ideaXme's Tokyo 2020 playlist in the lead up to both the Olympics and Paralympics 2020. This interview is the first of many interviews with the top athletes who are set to take part. Credits: Filming by Alan Johnson and Parth Kakkar Metfilm. From 16 December 2019, interview transcript: www.radioideaxme.com. This interview is dedicated to Michael Seres, founder of 11Health and ideaXme health ambassador who was supposed to interview Ali but is undergoing STEM cell treatment and chemotherapy for Crohn's disease. Get well soon Michael! ideaXme is a global podcast, creator series and mentor programme. Mission: Move the human story forward!™ ideaXme Ltd.
Dr Shima Beigi, BSc,MSc,MSc,Ph.D founder of Mindfulness Engineering™️ and ideaXme Rich Connectedness™️ ambassador interviews Sayuri Tanaka, renowned raw food chef, yoga teacher, cookbook author, chef tutor and owner of Sayuri Healing Food “The best vegan food in Bali”. Vegan food and vegans 6% of U.S. consumers say they are vegan, a 600% increase compared to just 1% in 2014. In Great Britain, approximately 1.16% of the population (600,000 people) reported being vegan in 2018, a 300% increase from 2014, when 150,000, or 0.25% of the population, was reported. Numbers of those adopting a vegan lifestyle are rising across the world and are set to increase exponentially due to many sharing the opinion that being vegan not only represents a benefit to individual health and alleviates animal suffering but is also essential to the health of our planet. The Vegan Society: “If the world went vegan, it could save 8 million human lives by 2050, reduce greenhouse gas emissions by two thirds and lead to healthcare-related savings and avoided climate damages of $1.5 trillion” (Source: A Well Fed World). Shima Beigi comments: In this episode of ideaXme Rich Connectedness podcast series, I, Dr. Shima Beigi, founder of Mindfulness Engineering™️ and Rich Connectedness ambassador focus on the important subject of healing our planet. I connect with one of the most talented raw food chefs in the food industry, Sayuri Tanaka. Sayuri Tanaka founder of Sayuri Healing Food, in Bali. Sayuri is not only a world class raw food chef, but also a yoga teacher and businesswoman and author of several raw food guides. Originally from Japan, her passion for food started at a very young age; watching her mother cook! Growing up she took the seed with her and later on created her own raw food training academy in Bali. Sayuri Healing Food Together we explore the success story behind her Sayuri Healing Food. I met Sayuri in early months of 2019 when I was living in Bali for four months. Being a scientist, a yoga teacher myself and a consciousness coach in STEM industry, I’m highly motivated to integrate success and resilience lessons of other industries into the field of engineering. I asked Sayuri about three key lessons that have contributed to her successful community. In response she stated three lessons: Trust. Delegate. Flow. “You must trust people. You must delegate and you must let the organic nature of things run their course”. I think these are highly transmit-able points to the engineering world. The Sayuri Healing Food logo represents the circle, ENSO, or 円相 in Zen, translated to KUU, or 空, the source, essence, or nothing-ness, infinity and the whole universe. It expresses that everything is inter-connected in a chain of co-becoming and in a state of constant flow. Sayuri Food The plant-based food that we provide is summarised as “raw-living” food, mostly gluten-free with some simply cooked elements. Sayuri’s first choice is to use ethically and organic-grown resources wherever possible. They incorporate the ancient wisdom of Ayurveda, Traditional Chinese Medicine and Macrobiotic. Sayuri invites us to ask: “What if ‘what we eat’ is the easiest access for that alignment? What if all that radiant-ness within is possible from the simple act of “eating?”. “Did you know that every living being gives off light, called “bio-photons”? What if we eat more of the light? If “we are what we eat”, what food do you want to become? We serve predominantly raw-living food for its higher light and vibration to enhance our healing processes, healthy rejuvenation & longevity on the physical, emotional & spiritual level”. Sayuri Tanaka Sayuri’s call to action: “Let our food be the medium for us all to fulfil our every dharma – the true purpose of our here & now on this planet, to activate ourselves to reach our full potential, to heal & balance our body, mind & spirit, for each all living beings. May we re-connect to the infinite universe within, find our every individual path for a sustainable radiant healthy lifestyle!” To know more about Sayuri Cookbooks please visit http://ur0.work/eK6V To learn about her Raw Food online course please visit: https://www.veecoco.com/raw-vegan-online-course Credits: Dr. Shima Beigi interview text, video, and audio. Follow ideaXme on Twitter:@ideaxm On Instagram:@ideaxme Find ideaXme across the internet including oniTunes,SoundCloud,Radio Public,TuneIn Radio,I Heart Radio, Google Podcasts, Spotify and more. ideaXme is a global podcast, creator series and mentor programme. Mission: Move the human the human story forward!
Hollie Fraser, founder of Books On The Move, worldwide book sharing movement, creative director and ideaXme literature, reading and writing ambassador interviews Matthew Newman, 2019 best Kindle book author. Matthew S. Newman, is a 39 year old cancer survivor and best-selling author of Starting At The Finish Line. He is a fitness aficionado, and a financial services industry speaker. His mission is help the wider public and to encourage financial preparedness. He does this by telling his story of brain cancer survival and the financial lessons and wisdom he learnt as a result. Matthew's book was named a Best Kindle Unlimited Books for 2019. To this day, fitness is still a big part of his life. You can see him here working out shortly after brain surgery! https://www.youtube.com/watch?v=J2G-S... He is a TedX Talk participant and currently traveling the country giving talks to financial services organizations, such as Transamerica, Primerica, Raymond James and more. https://matthewsnewman.com/speaking For the text version of this interview please visit www.radioideaxme.com from week commencing 2 December 2019. Interview credits: Hollie Fraser https://www.booksonthemoveglobal.com/... ideaXme is a global podcast, creator series and mentor programme. Mission: Move the human story forward! ideaXme Ltd
Dr Shima Beigi, BSc,MSc,MSc,Ph.D founder Mindfulness Engineering™️ and ideaXme Rich Connectedness™️ ambassador interviews Dr Eric Pearl, founder Reconnective Healing®️ and Jillian Fleer Head, of Insight and Development Reconnective Healing®️. Shima Beigi comments: As a resilience scientist, I’m aware of the imprints traumatic events create on both the mind and the body. The seminal work of Renowned trauma expert Bessel van der Kolk, “The body Remembers the Score”, demonstrates that although traumatic events alter brain’s wiring leading to post traumatic symptoms, therapeutic methods such as mindfulness, neurofeedback and other mind-body practices can shift the brain toward balance and wellbeing. It’s clear that healing is more than signs and symptoms that the body shows. The work of other prominent researchers in the field such as Dr. Peter Levine originator of the Somatic Experiencing®️ method further shows that by assisting traumatised individuals to enhance tolerance for body sensations stemming from trauma, the body and mind release residual effects of stressors. In short, the mind body connectivity relaxes into normality. As a result, it inactivates healing. In recent years, alternative healing methods have gained the attention of the mainstream. Healing modalities, holistic therapies, indigenous methods such as shamanic plant medicine healing, and sound healing are becoming more and more accessible. However, to many people to consider holding one’s hands in the air and delicately playing with what it seems to be an invisible ball of energy to be called a science backed healing method, can still sound and feel unreal. To find the truth, I, Dr. Shima Beigi, founder of Mindfulness Engineering™️ and the ambassador for Rich Connectedness™️ podcast series, have decided to personally experience the method of Reconnective Healing®️ through a certified practitioner in Belgium and invite Dr. Eric Pearl founder Reconnective Healing®️ and Jillian Fleer head of development programme to be my guests in this episode of ideaxme podcast series.As usual, we start with the tradition of ideaxme, which is asking big questions such as who are you! Our subject of discuss revolves around scientific and spiritual dimensions of healing from trauma and continues to develop into healing from collective trauma. According to Dr. Eric Pearl, Reconnective Healing®️ doesn’t promise the societal notion of healing from a disease. It rather provides a catalyst for the self healing capacity of the body and the intelligence of the consciousness to take over and create the best possible outcome. This best outcome sometimes shows itself in real symptom free conditions while other times it can be in the form of an insight to change one’s point of view, lifestyle and perception. Jillian believes that Reconnective Healing®️ works with the whole of the individual, with the consciousness, the greater intelligence. Join me in this episode of Rich Connectedness™️ podcast series, and share your healing stories. Have you tried Reconnective Healing? What other healing techniques have you used and were they helpful? Don’t forget to Move the human story forward™️ by subscribing, sharing and commenting. ideaXme is a global podcast, creator series and mentor programme. Mission: Move the human story forward!™️ ideaXme Ltd. Find ideaXme across 10 audio platforms including iTunes, Stitcher and Spotify, on YouTube and here www.radioideaxme.com. Twitter @ideaxm Instagram @ideaxme
Ira Pastor, ideaXme exponential health ambassador interviews Lisandra Rickards, CEO at Branson Centre of Entrepreneurship, Caribbean and Founder @ Merrivale Ventures LLC (Soul Career). Rickards has spearheaded the Centre’s strategic shift towards a venture capital model, supporting growth stage entrepreneurs towards investment. She has raised funding for the expansion of the Centre’s mission and relocated its headquarters from Montego Bay to the business hub of Kingston. Ira Pastor comments: On the past few episodes we’ve been taking a virtual around-the-world jaunt, from Palau in the remote South Pacific to Mauritius in the Indian ocean, talking with various thought leaders and visionaries about the themes of innovation, entrepreneurship, technology, and economic development. But we have yet to really explore the topic of the ”blue economy”, which is a general term in economics relating to both the exploitation and preservation of the marine environment. According to the World Bank's definition, the blue economy is the "sustainable use of ocean resources for economic growth, improved livelihoods, and jobs while preserving the health of ocean ecosystems." In addition to traditional ocean activities such as fishing, tourism and shipping, the blue economy entails emerging industries including renewable energy, aquaculture, seabed extractive activities, marine biotechnology, and bio-prospecting. Blue economy also attempts to embrace ocean ecosystem services that are not captured by the market but provide significant contribution to economic and human activity. They include carbon sequestration, coastal protection, waste disposal, and the existence of biodiversity. A 2015 World Wildlife Fund (WWF) briefing puts the value of key ocean assets over US$24 trillion, employing over 3 million people globally. Today, I’m joined by Ms. Lisandra Rickards, who is the Chief Entrepreneurship Officer at the Branson Centre of Entrepreneurship – Caribbean, headquartered in Kingston, Jamaica, a nonprofit formed through the philanthropic organization, Virgin Unite, the not-for-profit foundation of the Virgin Group, the British multinational venture capital conglomerate founded by entrepreneur Sir Richard Branson. As CEO, Lisandra spearheads the Centre’s strategy to support growth-stage entrepreneurs towards investment and raises funding for the expansion of the Centre’s mission. She previously headed the Programmes department, developing equity, loan, crowdfunding and grant opportunities, designing and developing the core content for the Centre’s free and open on-line platform, helping to launch the Alpha Angels Network of business angels in Jamaica, as well as doing impact analysis and reporting. Before joining the Branson Centre, Lisandra conducted economic and statistical research for the best-selling books Freakonomics and Superfreakonomics; consulted for the Ministry of Finance in Jamaica; worked at Bain & Company in New York City; and helped develop the global brand strategy for Caribbean conglomerate GraceKennedy. She was previously a Director of Business Development at the RMP Group, a private investment firm based in Orlando, Florida that targeted businesses in the United States currently servicing Fortune 1000 clients for investments of growth capital. Lisandra has an MBA with First-Year Honors from Harvard Business School, and a B.A. in Economics from the University of Chicago, where she graduated Phi Beta Kappa and Student Marshal. In 2008, she was featured in the CNBC documentary The Money Chase: Inside Harvard Business School. On this episode of ideaXme we will hear from Lisandra: - About her background, her career journey, and her role as CEO of the Branson Centre of Entrepreneurship. - About top economic issues the CARICOM region is facing in 2019. - About the Branson Centre of Entrepreneurship Blue Economy investments. - About her views on industries such as cannabis and medical tourism in the CARICOM region. - About other investments of Branson Centre of Entrepreneurship and future visions. ideaXme is a global podcast, creator series and mentor programme. Mission: Move the human story forward!™ ideaXme Ltd. You can listen to this podcast on 10 audio platforms including iTunes, Google Podcast and Stitcher. Find ideaXme's blog here: www.radioideaxme.com. Follow on Twitter @ideaxm on Instagram @ideaxme.
Ira Pastor, ideaXme exponential health ambassador interviews Dr. Thomas Boothby, Assistant Professor from the Department of Molecular Biology, University of Wyoming. Ira Pastor comments: A few episodes ago we began to segway into a fascinating area of biology that has broad potential applications across various domains of human health and enhancement, and that was the theme of organism dormancy. We got our feet wet in talking about the topic of torpor, which ?is defined as a state of decreased physiological activity in an animal, usually by a reduced body temperature and metabolic rate, which ?enables animals to survive periods of reduced food availability ? and we spent time on the topic of the arctic ground squirrel research being done at University of Alaska. On today's show we are going to go a few levels of extreme further as we touch on the topic of cryptobiosis, which is defined is an extreme metabolic state of life entered by an organism in response to extreme adverse environmental conditions such as desiccation, freezing, and oxygen deficiency. In the cryptobiotic state, all measurable metabolic processes stop, preventing reproduction, development, and repair. When environmental conditions return to being hospitable, the organism will return to its metabolic state of life as it was prior to the cryptobiosis. And I don't think one could argue that the true "king of the hill" on this planet when it comes to such cryptobiotic skills, are the Tardigrades, known colloquially as "water bears" or "moss piglets", a phylum of water-dwelling eight-legged segmented micro-animals. These organisms are found living everywhere, from mountaintops, to the deep sea and mud volcanoes, from tropical rain forests to Antarctica. Tardigrades are among the most resilient animals known, with individual species able to survive extreme conditions, such as exposure to extreme temperatures, extreme pressures (both high and low), air deprivation, radiation, dehydration, and starvation that would quickly kill most other known forms of life. Tardigrades have also survived exposure to the vacuum of outer space. Ira Pastor comments: Today, we are joined by someone who really knows this species and its biology the best, and that is Dr. Thomas Boothby, Assistant Professor from the Department of Molecular Biology, University of Wyoming, whose core areas of study are the molecular mechanisms of extreme ?stress tolerance (also defined as "Biology at the Limits of Life"). Dr. Boothby got his Ph.D. at the University of Maryland in Cell and Molecular Biology, studying mechanisms of recovery, gene expression regulation, and morphogenesis, after prolonged desiccation, in certain plant species. Then he spent several years at University of North Carolina at Chapel Hill doing post-doctoral research and studying the biochemistry and mechanisms of extremo-tolerant organisms. Today we will hear from Dr. Boothby about: - His background and how he developed an interest in science, in nature, and in this unique domain of study. - About the topic of Intrinsically Disordered Proteins (IP) - a group of proteins that lacks a fixed or ordered three-dimensional structure, which is partially responsible for imparting the tardigrade's extreme biological robustness. - Other interesting mechanisms of extremo-tolerant organisms - About his work and ideas as related to the Defense Advanced Research Projects Agency (DARPA) Biostasis Program, which is focused on the? "golden hour" for saving a life in a catastrophic emergency - (DARPA is an agency of the United States Department of Defense responsible for the development of emerging technologies for use by the military). - Other "science fiction" topics related to tardigrade biology learnings for human enhancement, such as possibilities for deep space travel and suspended animation / cryonics - Any near-term insights from tardigrade research on human aging. ideaXme is a global podcast, creator series and mentor programme. Mission: Move the human story forward!™ ideaXme Ltd.
Dr Shima Beigi, BSc,MSc,MSc,Ph.D ideaXme rich connectedness ambassador interviews Dr Dean Radin, Chief Scientist at the Institute of Noetic Sciences. Imagine the possibility of a new attitude to scientific exploration that allows us to explore the most fundamental behaviour of our fabric of reality. For the past centuries, science has relied on materialistic explanations of the world. This reality is often called Newtonian world view, where everything can be described through “laws of nature”. Nevertheless, we are at a point in human development where this reality has already started to fall apart. We are gradually waking up to a need for an alternative way of explaining the world around us. Many scientists, scholars, thought leaders, artists have embarked on this journey to the unknown and have independently arrived at a set of unified realisations: A holistic world view is humanity’s way forward. That, our minds influence our reality in measurable ways. That, the brain can be a quantum machine. That, our ancestral knowledge hold key to the future progression of sciences. That, a sustainable world requires our intentional participation in creating a new world. In this episode of ideaXme's Rich Connectedness™ podcast series, I, Dr. Shima Beigi, Founder of Mindfulness Engineering™ connects with Dr. Dean Radin, Chief Scientist at the Institute of Noetic Sciences and author of several bestselling and award-winning books including Entangled Minds, Conscious Universe. Together, we explore the evolution of scientific understanding of the nature of mind, and its correlations with the world and examine whether we need a more comprehensive way to unlock the nature of consciousness. You can join this conversation in the comment box below or follow the discussion on our other social media platforms. You can read more about Dr. Radin at http://deanradin.com/NewWeb/bio.html ideaXme is a global podcast, creator series and mentor programme. Mission: Move the human story forward!™ ideaXme Ltd.
Ira Pastor ideaXme exponential health ambassador interviews Mr. Dennis Kowalski, Cryonics Institute President, EMT-paramedic, certified in advanced cardiac life support (ACLS), advanced pediatric life support (PALS), a CPR Instructor for the American Heart Association, and a fire fighter! Ira Pastor comments: Cryonics is defined as the extremely low-temperature freezing (or vitrification - converting into glass or a glass-like substance) usually at −196 °C or −320.8 °F or 77.1 K, and storage of a human body or part of a human body, with the hope that resurrection may be possible in the future. Cryonics procedures can legally begin only after clinical death, and cryonics "patients" are legally dead. Cryonics procedures ideally begin within minutes of death, and use cryo-protectants to prevent ice formation during cryo-preservation The first person to be frozen via cryonics was that of Dr. James Bedford in 1967. It’s estimated that over 300 bodies had been cryo-preserved in the United States, and a couple thousand people have made arrangements for cryo-preservation to date. While it is not yet possible for a dead body to be re-animated after undergoing vitrification, in order to revive patients in the future, it will be necessary to be able to cure any diseases which lead to death, repair cells damaged in the freezing process, and repair cells damaged by the ageing process. The Cryonics Institute (CI) is an American not-for-profit corporation that provides cryonics services to both humans and pets. The Cryonics Institute was founded by the “Father of Cryonics” Robert Ettinger, in 1976, who introduced the concept of cryonics with the publication of his book “The Prospect of Immortality” published in 1962, and he served as their president until 2003. Today, I’m joined by Mr. Dennis Kowalski, who is not only the current Cryonics Institute President, but is also a nationally registered EMT-paramedic, certified in advanced cardiac life support (ACLS), advanced pediatric life support (PALS), a CPR Instructor for the American Heart Association, and a fire fighter, so he has had a lot of experience dealing with life, saving lives while helping others in great distress, emergency triage at mass casualty incidents, and unfortunately death, but his experience provides for an interesting discussion and bridge between conventional emergency medicine and cryonics. On this show we will hear from Mr. Kowalski: About his background and how he developed an interest in cryonics. About the current legal dynamics surrounding cryonics and the cryo-preservation process for a human subject. About the technical steps involved in cryo-preservation of a human subject About financial issues surrounding running a cryonics operation and long term storage of cryonics subjects. About future visions in the cryonics space. From week commencing 18 November find all the relevant links visit www.radioideaxme.com. Listen to our ideaXme interviews on across the internet on iTunes, Stitcher, Spotify, Radio Public, TuneIn Radio, FM Player, SoundCloud.... ideaXme is a global podcast, mentor series and creator series. Mission: Move the human story forward!™ ideaXme Ltd.
Ira Pastor, ideaXme exponential health ambassador and founder of Bioquark, interviews Dr. Renard Siew, Climate Change Advisor with the Centre for Governance and Political Studies in Kuala Lumpur. Today we are going to be talking about Sustainability and Climate Change; two topics that have really come to the public forefront in recent months, and which directly impact all of our respective health and longevity. Dr. Renard Siew Our guest today is Dr. Renard Siew. Dr. Siew has PhDs in both Civil and Environmental Engineering (Cambridge University) and Management, Technology and Economics (ETH Zürich PhD). Dr. Renard Siew is a Climate Change Advisor with the Centre for Governance and Political Studies in Kuala Lumpur which is an interdisciplinary research center, bridging the fields of economics, political science, sociology, business and law, which focuses on the problems and challenges raised by the current political development and economic transformation. He is also part of the World Economic Forum Expert Network Group focusing on Sustainable Development in Asia, and as environmental advisor to Sime Darby Holdings, is involved in implementing the environmental agenda for this multinational conglomerate based in Kuala Lumpur with operations across key growth industry sectors including Plantation, Property, Industrial, Motors, Energy and Utilities as well as Healthcare. Prior to this, he was a postdoctoral fellow with the Centre for Energy and Environmental Markets (CEEM). He continues to serve as a Stakeholder Council Member for the Global Infrastructure Basel Foundation, as a Global Advisory Board Member of Economists Without Borders and is the Curator of Global Shapers Kuala Lumpur, a not-for-profit organization focusing on creating sustainable impacts in Malaysia. He actively participates and contributes in various stakeholder platforms including the ‘Water for Growth’ initiative and the Integrated Urban Water Management task force seeking to develop a National Level Water Transformation Roadmap for Malaysia. He is a Climate Reality Leader trained by Al-Gore, former Vice President of the USA, in Pittsburgh. He was the recipient of the Yayasan Sime Darby Scholarship, Cambridge Bursary Scholarship, ARG Hermes Scholarship, Brookfield Multiplex Engineering Management Prize and the Australian Conferences Management Education for Engineers Award. For his work in sustainability, he was also named as one of Malaysia's Top 10 Most Inspiring Green Warriors, 100 Visionary Young Leaders Leading Us Towards a Better World by Real Leaders Magazine, received a Forbes Fellowship, was a 2017 Augustman A-Lister and bestowed with the Ten Outstanding Young Malaysians (TOYM) Award for Environmental Leadership. He is also named as a Young Leader of the World Cities Summit a select group of change-makers from diverse sectors working on shaping the global urban agenda and a 2018 Asia 21 Young Leaders. His work has been featured across a number of mainstream media such as The Star, New Straits Time, The Edge, Focus Malaysia, Malaysia Tatler, Malaysia SME, Korean Times, Kuwait Times among others. On this episode we will hear from Dr. Siew: About his background, how he became interested in engineering, economics, and how he finds himself in 2019 at the epicenter of the global climate change movement. His goals for “future-proofing” our planet and keeping global temperatures within the 1.5 degrees Celsius critical change mark. His experiences working for a large natural resources company as sustainability advisor. His ideas for promoting entrepreneurship to address climate change and sustainability. His views towards how society must adapt and create better environments for the aging population within the "built environment" system. For all the relevant links corresponding to this interview please visit www.radioideaxme.com. ideaXme is a global podcast, creator series and mentor programme. Mission: Move the human story forward!™ ideaXme Ltd.
Ira Pastor, ideaXme longevity and aging ambassador and founder of Bioquark, interviews Dr. David Fajgenbaum, Assistant Professor of Medicine in the Division of Translational Medicine & Human Genetics at University of Pennsylvania, Associate Director, Patient Impact of the Penn Orphan Disease Center, Founding Director of the Castleman Disease Center, and Co-Founder & Executive Director of the Castleman Disease Collaborative Network (CDCN). Ira Pastor Comments: A rare disease is defined as any disease that affects a small percentage of the population. In the United States, the Rare Diseases Act of 2002 defines rare disease strictly according to prevalence, specifically "any disease or condition that affects fewer than 200,000 people in the United States", or about 1 in 1,500 people. This definition is essentially the same as that of the Orphan Drug Act of 1983, a federal law that was written to encourage research into rare diseases and possible cures. In Japan, the legal definition of a rare disease is one that affects fewer than 50,000 patients in Japan, or about 1 in 2,500 people. The European Commission on Public Health defines it meaning fewer than 1 in 2,000 people, but contains some cut-offs for diseases that are not chronically debilitating or inadequately treated. The US organization Global Genes has estimated that more than 300 million people worldwide are living with one of the approximately 7,000 diseases they define as "rare" per the United States definition. Chronic genetic diseases are commonly classified as rare, and among the 7000 conditions mentioned above, rare diseases may result from bacterial or viral infections, allergies, chromosome disorders, degenerative and proliferative causes, and may effect any body organ. Dr. David Fajgenbaum Today's guest, who I'm honored to have join us to further delve into this topic, not just from the perspective of a clinician and investigator, but also as a patient himself, is Dr. David Fajgenbaum, MD. Dr. Fajgenbaum earned his MD from the Perelman School of Medicine at the University of Pennsylvania, and is an Assistant Professor of Medicine in the Division of Translational Medicine & Human Genetics at Penn, Associate Director, Patient Impact of the Penn Orphan Disease Center, Founding Director of the Castleman Disease Center at Penn, and Co-Founder & Executive Director of the Castleman Disease Collaborative Network (CDCN). Dr. Fajgenbaum leads the Castleman Research Program at Penn as principal investigator of 18 translational research studies, including an international natural history study and the first-ever NIH funded research of idiopathic multicentric Castleman disease (iMCD). His published research has changed the way iMCD is researched and treated and as a patient himself, is in his longest remission ever thanks to a precision treatment that he identified. He is also the author of Chasing My Cure: A Doctor's Race to Turn Hope Into Action Dr. Fajgenbaum co-founded the Castleman Disease Collaborative Network in 2012 to accelerate research and treatments for Castleman disease through a 'Collaborative Network Approach,' a business-inspired approach to biomedical research, which has become a blueprint for advancing rare disease research. Dr. Fajgenbaum is also the Co-Founder of the National Students of AMF Support Network (Actively Moving Forward), a non-profit organization dedicated to supporting grieving college students due to a loved one's diagnosis or death (or their own diagnosis) of a terminal illness. He co-authored "We Get It: Voices of Grieving College Students and Young Adults," a book for grieving college students and those who wish to support them. Dr. Fajgenbaum's work has been highlighted by the New York Times, Science, Today Show, Reader's Digest, Forbes Magazine, Perelman School of Medicine, World Affairs Council of Philadelphia, College of Physicians of Philadelphia, Everylife Foundation, Global Genes, and the University of Colorado. Dr. Fajgenbaum also received his MBA from Penn, at The Wharton School, where he was awarded the Joseph Wharton Award, Core Value Leadership Award, Kissick Scholarship, Wharton Business Plan Competition Social Impact Prize, Eilers Health Care Management Award, Mandel Fellowship, and Commencement Speaker., where he was a 21st Century Gamble Scholar. On this show we will hear about: Dr. Fajgebaum's background and life before his diagnosis with Castleman's disease, and his interest in becoming a doctor. The events surrounding his diagnosis with Castleman's disease in 2010. His discovery in 2012 of his own personal therapeutic regimen that helped put him into remission. His development of the Castleman Disease Collaborative Network. A discussion of drug "re-purposing" in the area of rare diseases. Finally, a discussion of his future research visions in the rare disease space. visit www.radioideaxme.com for all of the links. ideaXme is a global podcast, creator series and mentor programme. Mission Move the human story forward!™ ideaXme Ltd.
Andrea Macdonald, founder ideaXme Ltd. interviews Dr Sam Illingworth, PhD Atmospheric Physics, Senior Lecturer in Science Communication at Manchester Metropolitan University in the UK. Dr Illingworth is a "poet scientist" who believes that poetry is a powerful tool to communicate and explore science. (For the complete transcript of this interview please visit www.radioideaxme.com) He is passionate about encouraging the cross fertilisation of ideas from one seemingly unrelated sector to another to create stronger ideas. And feels that when the arts and sciences are brought together the results are powerful, often moving both unrelated sectors forward. He also believes strongly in the necessity of scientists to communicate their science with the wider world so that people better understand and evaluate how some of the most pressing global issues such as climate change can be solved by science and public participation in tandem. Sam urges us all to learn more of science generally in this age of exponential growth in scientific advancement and technology. As he’d like the public to be equipped with the necessary knowledge to question and ultimately take part in the processes that affect us all. Poetry and science as parallels: Dr Illingworth has conducted extensive research into the lives and achievements – poetic and scientific of 6 fellow famous poet scientists. These findings have been published in a recent book, A Sonnet To Science. He evaluates through these 6 examples how science is communicated and advanced by poetry. Climate change Dr Illingworth’s special scientific interest lies in climate change research. He has a PhD in Atmospheric Physics and a Masters Degree in Physics with Space Science and Technology from the University of Leicester (and an MA in Higher Education Merit from The Manchester Metropolitan University). He has worked with the Manchester Climate Change Agency on the Climate Lab 2016 programme, an initiative to engage the public with the issue of Climate Change. He wrote A Change of Climate with his friend and colleague, Dan Simpson, who he mentions in this interview. Watch to the end of the interview and you’ll learn how science and poetry really can be symbiotic. Furthermore, you'll hear of Dr Illingworth's passion for music also and how it too can be used like poetry to communicate science. Also discover that Sam’s work is not just limited to teaching university students. His outreach programme also extends to schools as he recognises importance of engaging children in major world issues. Finally, find out with whom Sam has connected in the past to move his life and career forward as well as who he would like to meet now. For some extra entertainment and inspiration - throughout the interview - expect to hear some wonderful poetry! To read the full transcript visit our blog www.radioideaxme.com. ideaXme is a global podcast, creator series and mentor programme. Mission: Move the human story forward!™ ideaXme Ltd.
Dr Shima Beigi, BSc,MSc,MSc,Ph.D. Founder of Mindfulness Engineering™, resilience scientist, consciousness coach and ideaXme Rich Connectedness™ ambassador interviews Estas Tonne, worldwide acclaimed guitarist who stars in Time of the Sixth Sun, a movie and documentary series about "global consciousness and the emerging movement to find a new way to walk more lightly on this Earth". Shima Beigi comments: It is easy to be carried away by today’s hyperconnected world and forget the very basics of our human condition: the need for connection. How can we create a balance between life with technology and life without technology? Who has the answer; Scientists? Artists? Spiritual leaders? Are we heading towards some overwhelming information world where we become too busy to enjoy togetherness? How can scientists become more mindful of technological design? How can we build and connect more from our "heart technology" to one another rather than our devices? In this episode of ideaXme's Rich Connectedness™ podcast series, I, Dr. Shima Beigi, Founder of Mindfulness Engineering™ connect with Estas Tonne, a world renowned guitarist who is best known for his transcendental and mystical performances. Together, we explore the delicate balance between the worlds of science, music and spirituality and the importance of creating a culture of digital empathy for emergence of a sustainable future. Technology connects. But it is human touch that transforms our digital platforms to mindful spaces. You can join this conversation in the comment box below, or follow the discussion on our other social media platforms. As well as on YouTube, this interview is available (from week commencing 11 November 2019) on ideaXme's blog www.radioideaxme.com and in audio format on 10 further platforms including iTunes, Stitcher, Spotify, SoundCloud, Radio Public and I Heart Radio. Rich Connectedness™ is an ideaXme research project exploring the power of human relationships and connection supporting both the evolution of individuals and of our species as a whole. ideaXme is a global podcast, creator series and mentor programme. Mission: Move the human story forward!™ ideaXme Ltd.
Ira Pastor, ideaXme exponential health ambassador and founder of Bioquark interviews Dr Ameenah Firdaus Gurib-Fakim, biodiversity scientist and former President of Mauritius 2015-2018. Today ,we are going to touch on several themes from recent shows (including natural products, bio-diversity, conservation, innovation, Africa, island nations, and micro-nations) and bring them together for what is going to be an exciting episode Throughout the 20th century, natural products (primarily those from plants, fungi, and bacteria) formed the basis for a majority of all pharmaceuticals, biologics, and consumer healthcare products used by patients around the globe, generating trillions of dollars of wealth. However, many scientists believe we have only touched the surface of what the natural world, and its range of organisms could teach us. Lately, novel research disciplines, including inter-kingdom signalling and semio-chemical communication, the respective abilities of one species living signals to affect the genome of another, not to mention in-depth study of the micro-biome and virome, are highlighting entirely new ways that non-human bio-products can affect the human genome for positive transitions in health and wellness. Simultaneously, we are finding out more and more about the novel, combinatorial biochemical approaches that nature utilizes (as evolutionary dynamics would never follow the single magic bullet approach promoted by the pharma industry) to address multiple levels of the disease-biome simultaneously. Such integrated dynamics that nature uses, represent a major contrast when compared to the reductionist, highly siloed model at play in the pharma industry today. As current environmental disasters continue to remind us, hundreds of millions to billions of years of evolutionary knowledge locked up in such species, can be wiped out and lost forever- so we need to keep this in mind as we efficiently tap this treasure trove of potential in the 21st century Dr. Ameenah Firdaus Gurib-Fakim is a Mauritian biodiversity scientist and politician who served as the President of Mauritius from 2015 to 2018. Her autobiography is entitled "Ameenah Gurib-Fakim: My Journey". Dr. Gurib-Fakim is the first woman elected as President of the country and is the third woman to have served as Head of State following QE2 and Monique Ohsan Bellepeau. She graduated from the University of Surrey in 1983 with a BSc degree in chemistry. After obtaining her PhD degree in organic chemistry at Exeter University, she returned home in 1987 to take employment at the University of Mauritius, where she was a Professor with a chair in Organic Chemistry. She served as Dean of the Faculty of Science and Pro Vice Chancellor.She also worked at the Mauritius Research Council as Manager for Research (1995-1997). She worked as Managing Director of CIDP Research & Innovation (formerly Cephyr, Centre for Phytotherapy Research) and had been involved in publishing several scientific books / chapters in books on related topics including but not limited to: Mauritius through Its Medicinal Plants: towards a better understanding of medicinal plants of the Indian Ocean Islands; Novel Plant Bioresources: Applications in Food, Medicine and Cosmetics; Chemistry for Sustainable Development in Africa; Floral Biodiversity of the Mascarene Islands; Medicinal and Aromatic Plants of the Indian Ocean Islands, and Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components: Harnessing Traditional Knowledge to Treat Existing and Emerging Infectious Diseases in Africa, She served as the Chairperson the International Council for Scientific Union Regional Office for Africa (2011 -2014) prior to her Presidency of Mauritius Dr. Gurib-Fakim has also been the recipient of international awards including the L'Oreal-UNESCO Award for Women in Science, Laureate for the National Economic and Social Council, the Technical Centre for Agricultural and Rural Cooperation and New Partnership for Africa's Development for African Women in Science and the African Union Award for Women in Science. She was also made Commander of the Order of the Star and Key of the Indian Ocean (CSK) by President Anerood Jugnauth in 2008 for her contribution in the education and the scientific sector. She was awarded the Order of the Chevalier de Ordre des Palmes Academiques by the Government of France in 2009. Upon becoming President, she was elevated to the highest civilian award of Grand Commander of the Star and Key of the Indian Ocean (GSCK). In 2015, she was named the vice-chairman and trustee of the Planet Earth Institute. Here, Dr. Gurib-Fakim talks of: - About her background, how she developed an interest in science, in chemistry, in phyto-medicine, in environmentalism, and in politics, and how she rose to prominence in the Mauritian political system - About her vision regarding the world needing "real policies for properly communicating science to the people - About her vision for Africa becoming a supplier of human talent and capital to the world. - About her views on African sustainable development - About her future plans For all the links relating to this show please visit www.radioideaxme.com ideaXme is a global podcast, creator series and mentor programme. Mission: Move the human story forward!™ideaXme Ltd.
Ira Pastor, ideaXme exponential health ambassador and founder of Bioquark, interviews Dr. Manabu Kinoshita, Associate Professor of Immunology, Department of Immunology and Microbiology, at the National Defense Medical College in Tokorozawa, Saitama, Japan. Blood Transfusions Today the ideaXme show is going to travel around the world to Japan, to discuss the topic of artificial blood technology. Blood transfusions save lives and improve health, but many patients requiring transfusion in 2019 still do not have timely access to safe blood. The need for blood transfusion may arise at any time in both urban and rural areas. The unavailability of blood has led to deaths and many patients suffering from ill-health. Blood loss from traumatic injuries is responsible for thousands of deaths annually, and even when people survive, oxygen depletion can leave tissue permanently injured. Fresh blood can only be stored for 42 days, and only lasts for a few hours un-refrigerated. Currently, if you need to receive a blood transfusion, it must also be matched specifically with your blood type or the "universal donor," type, O negative. An adequate and reliable supply of safe blood is normally assured by a stable base of regular, voluntary, unpaid blood donors, and they are also the safest group of donors as the prevalence of blood-borne infections is lowest among these donors. The World Health Organization (WHO) estimates that around 120 million units of donated blood are collected globally every year. 42% of these blood donations are collected in high-income countries, home to less than 16% of the world's population. Blood Substitute A blood substitute (also called artificial blood or blood surrogate) is any substance that can be used to mimic and fulfill some functions of biological blood. It aims to provide an alternative to blood transfusion, which is transferring blood or blood-based products from one person into another. Thus far, there are no well-accepted oxygen-carrying blood substitutes, which is the typical objective of a red blood cell transfusion; however, there are widely available non-blood volume expanders for cases where only volume restoration is required. A full substitute could be vital in settings like battlefields or rural areas without easy access to blood, used as a stopgap measure to keep the injured alive until they get to a hospital. Also, a one-size-fits-all blood substitute would overcome all sorts of existing obstacles, ranging from not enough donations by ethnic minorities, to finding matches for rare blood types. Dr. Manabu Kinoshita Today's guest joining us to go further into this topic, to discuss the challenges and possibilities of achieving a universal blood substitute, is Dr. Manabu Kinoshita, Associate Professor of Immunology, Department of Immunology and Microbiology, at the National Defense Medical College in Tokorozawa, Saitama, Japan. Dr. Kinoshita is a surgeon who specializes in both immunology (with a focus on host-defense dynamics against surgical stress) as well as nano-medicine, including red blood cell substitutes, platelet substitutes, and nanosheets for Biological Applications such as wound healing. The National Defense Medical College is Japan's six-year university-level military academy under control of the Ministry of Defense whose objectives are to train future military officers who are also medical doctors and current military doctors. Students graduate with an advanced level of theory and application of medical sciences required to conduct the missions of the Japan Self-Defense Forces and acquisition of research capability of the related fields as well as to offer training of clinical medicine. On this who we will hear from Dr. Kinoshita: About his background and interest in surgery, trauma, and the focus on artificial blood substitutes. An introduction to the work of the National Defense Medical College. His recent work and discoveries about his artificial blood product, profiled in the Journal of Transfusion paper entitled Combination Therapy Using Brinogen-chain peptide-coated, ADP-encapsulated Liposomes and Hemoglobin Vesicles for Trauma-induced Massive Hemorrhage in Thrombocytopenic Rabbits. His future visions for the project, and other research projects he is working on. For all the relevant links for this interview please visit www.radioideaxme.com. ideaXme is a global podcast, creator series and mentor programme. Mission: Move the human story forward!™ ideaXme Ltd.
Ira Pastor, ideaXme exponential health ambassador and founder of Bioquark, interviews Dr Wise Young M.D., Ph.D., the Richard H. Shindell Chair in Neuroscience, Distinguished Professor of Cell Biology & Neuroscience and the Founding Director of the W. M. Keck Center for Collaborative Neuroscience at Rutgers University. Spinal Cord Injury A spinal cord injury (SCI) is defined as any damage to the spinal cord that causes temporary or permanent changes in its function. Symptoms may include loss of muscle function, loss of sensation, or autonomic function in the parts of the body served by the spinal cord below the level of the injury. Injury can occur at any level of the spinal cord and can be a complete injury, with a total loss of sensation and muscle function, or incomplete, meaning that some nervous signals are able to travel past the injured area of the cord. Depending on the location and severity of the damage, the symptoms vary, from numbness to paralysis to incontinence. Long term outcomes also vary widely, from full recovery to permanent quadriplegia or paraplegia. Complications can include muscle atrophy, pressure sores, infections, and breathing problems. Direct medical expenses for spinal cord injuries can run into millions of dollars (not including lost wages and earning potential) and can include: spinal surgery, trauma care (use of a ventilator) rehabilitation (including physical and occupational therapy, speech therapy, and mental health counseling), long-term care, including the costs of in-home aides, medical equipment such as wheelchairs, and medication such as painkillers and antibiotics. A recent estimate showed that there are about 18,000 new SCI cases each year in the U.S. and the number of people with SCI living in the United States is around 290,000. Dr. Wise Young Today’s guest is going to take us further into the area of spinal cord injury as well as discussing some of the most exciting work that’s going on in the development of innovative therapeutic intervention for SCI. Today’s speaker is Dr. Wise Young, who with a Doctorate in Physiology and Biophysics from the University of Iowa, and a medical degree from Stanford University has committed himself to bringing innovative treatments to people with spinal cord injuries over the last few decades. Speaking on how he felt compelled to work in tackling spinal cord injuries, Dr. Young expresses how “I was an intern at Bellevue Hospital when I took care of my first spinal cord injury patient. It was very emotional for me because I think one of the things that all doctors hate to feel is helpless, to feel as if there's nothing you can do.” He continues, “this is really one of the most hopeless conditions in human history where patients are told that they will never walk again. And so, I decided to take on a subject that I think most of my colleagues believed would be a waste of time.” Inspired by the hopelessness of the condition, he went on to build and train a twenty-five center clinical trial network in China, Taiwan, and Hong Kong where Phase II human clinical trials using umbilical cord blood mononuclear cells and lithium are currently on-going. Today, he is working on establishing clinical trial networks in the United States, Norway, and India. Dr. Young led the team that discovered and established high-dose methylprednisolone (MP) as the first effective therapy for spinal cord injuries. This 1990 work upended concepts that spinal cord injuries were permanent, refocused research, and opened new vistas of hope. He also developed the first standardized rat spinal cord injury model used worldwide for testing therapies, formed the first consortium funded by the National Institutes of Health (NIH) to test promising therapies, and helped establish several widely accepted clinical outcome measures in spinal cord injury research. Speaking on the development of the Phase II trials, Dr. Wise explains how he first witnessed them take place in Kunming, China. “There was an army hospital there that really did something very unusual. They were taking patients after spinal cord injury and walking them six hours a day, six days a week for six months. It was called the six, six, six program. This caused many of the patients to recover function, I mean, as many as half of the patients recover walking.” Dr. Young founded and served as editor-in-chief of the Journal of Neurotrauma.He organizedthe International and National Neurotrauma Societiesas forums for scientists to collaborate on in the areas of spinal cord injury and brain research. He served on advisory committees for the NIH, National Academy of Sciences, and National Institute of Child Health and Human Development, and on many spinal cord injury advisory boards. His work has been featured in numerous national and international news and print publications including appearing on20/20 with Barbara Waltersand Christopher Reeve, Today with Katie Couric, 48 Hours, Fox News, CNN, and USA Today. TIME Magazine named Dr. Young America’s best in spinal cord injury research. Some of his many honors include: being the first researcher elected to the Spinal Cord Injury Hall of Fame, receiving NIH Jacob Javits Neuroscience "Cure" Award, a Trustees Award for Excellence in Research, an Asian American Achievement Award, and The Hope Award. On this show we will hear from Dr. Young: About his background, how he got interested in science, physiology and medicine, and how he finds himself at the epicenter of neuroscience and trauma care. He will discuss his cell therapy approaches in SCI and his supportive interventions in SCI. He will also talk about his "morphodynamic" interventions in SCI and go into his international work in Asia and Norway. ideaXme is a global podcast, creator series and mentor programme. Mission: Move the human story forward!™ ideaXme Ltd.
Ira Pastor, ideaXme longevity and aging ambassador and founder of Bioquark, interviews Dr. Virginia Byers Kraus, Professor of Medicine, Pathology, and Orthopaedic Surgery, and a faculty member of the Duke Molecular Physiology Institute in the Duke University School of Medicine. Ira Pastor Comments: Arthritis is a term often used to mean any disorder that affects joints (the most common forms being osteoarthritis (OA) and rheumatoid arthritis (RA)), where symptoms generally include joint pain, stiffness, redness, warmth, swelling, and decreased range of motion. In some types of arthritis (on the auto-immune side of things) other organs can be affected, and onset of arthritis can be gradual or sudden. There is no known cure for either rheumatoid or osteoarthritis. Joint replacement surgery may be required in eroding forms of arthritis. Treatment options vary depending on the type of arthritis and can include physical therapy, lifestyle changes (including exercise and weight control), orthopedic bracing, and various medications which can help reduce inflammation in the joint (and immune responses in case of auto-immune forms of arthritis) which can help decrease pain and potentially slow the rate of joint damage, hopefully to "zero", which is the nature of the current class of “holy grail-ish” type drugs in the Rheumatoid Arthritis space known as Disease Modifying Anti-Rheumatic Drugs (DMARDs). No drug fulfilling the criteria for a "Disease Modifying Osteoarthritis Drug " (or DMOAD) is approved by the regulatory agencies such as the FDA or EMEA. But whether one is looking for a DMOAD, or looking beyond the current state of the art of the DMARDs to the next RA holy grail type intervention, many thought leaders would agree that it would be a form of intervention that stimulates Chondrogenesis, or the process by which new fresh cartilage is created in the joint, literally reversing the pathogenesis of such diseases, as opposed to just slowing or stopping them. Once damaged in humans, cartilage has very limited repair capabilities. Because chondrocytes are bound in lacunae, they cannot migrate to damaged areas. Also, because hyaline cartilage does not have a blood supply, the deposition of new matrix is slow. Damaged hyaline cartilage is usually replaced by fibrocartilage scar tissue instead. But this is not the case in other species such as newts and zebrafish, where fresh cartilage is regrown and regenerates perfectly over a lifetime. Today’s guest who is going to take us further into all these themes is Dr. Virginia Byers Kraus. With an MD and PhD from Duke University, Dr. Kraus is Professor of Medicine, Pathology, and Orthopaedic Surgery, and a faculty member of the Duke Molecular Physiology Institute in the Duke University School of Medicine. She is a practicing Rheumatologist with 20 years’ experience in Osteoarthritis research. Dr. Kraus is past president of the Osteoarthritis Research Society International (OARSI), the premier organization focused on the prevention and treatment of osteoarthritis through the promotion and presentation of research, education, and the worldwide dissemination of new knowledge. In 2019, she was elected to the Association of American Physicians and awarded the Lifetime Achievement Award from OARSI. She is co-principal investigator of the OARSI/Foundation for NIH Osteoarthritis Biomarkers Consortium Project, which advances the validation and qualification of biomarkers for OA diagnosis, prognosis, and clinical trials. She also directs the Duke Biomarkers Shared Resource which is a facility that assists investigators with the design and implementation of molecular and protein assays to evaluate biochemical and inflammatory markers. Dr. Kraus is also the Director of the Molecular Measures Core in the Center for the Study of Aging and Human Development. On this show we will hear from Dr. Kraus: How she developed an interest in science, medicine, and rheumatology. The importance of appropriate biomarker development, validation and qualification in the diagnosis, prognosis, and development of effective interventions in arthritis. Her recent paper entitled Analysis of “Old” Proteins Unmasks Dynamic Gradient of Cartilage Turnover in Human Limbs, in which she highlights the discovery of interesting protein / microRNA constituency differences of various joints of the body, leading to clues for different regenerative medicine interventional possibilities. Finally, we’ll discuss her work in the Molecular Measures Core in the Center for the Study of Aging and Human Development where her group is focused on "understanding the means to optimize whole person reserve and resilience through analyses of molecular factors indicative of cellular and tissue level ability to withstand and recover from stressors.” ideaXme is a global podcast, creator series and mentor programme. Mission: Move the human story forward!™ ideaXme Ltd.
Ira Pastor, ideaXme longevity and aging ambassador and founder of Bioquark, interviews evolutionary biologist, researcher, and author, Dr. Josh Mitteldorf. Ira Pastor Comments: On the last couple of shows we’ve been spending a lot of time on the different hierarchical levels of the aging processes, talking about the genome, the microbiome, tissue engineering, systems biology, and many other topics, and we’ve been speaking to a broad range of thought leaders in these various fields. As the study of aging and longevity as areas of biotherapeutic interventions has become more popular in recent years, an extensive catalogue has grown, and continues to grow, with everyone’s key aging hallmark, or damage target of interest, piling on the mix. This lengthy list, many of which we’ve touched on during the show, currently includes, but is not limited to, the following: inflammation, oxidation, heat shock, microbial burden, xeno-toxin accumulation, somatic mutations to the genome, epigenetic modifications, stem cell exhaustion, senescence cell accumulation, damaged mitochondria, telomere variability, ECM cross-linking, nutrient sensing dysfunction, intra / extra-cellular aggregates / junk accumulation, and so on. While this list, no doubt, contains a wide variety of fascinating topics connected to health and aging, and areas for potential intervention that may improve outcomes in various disease states associated with aging, we still have not yet touched on a unified picture of why we age in the first place. In addition, we have not yet touched on many of the paradoxes that get swept under the rug that challenge a lot of the ingrained doctrine in longevity biomedical research. These paradoxes include: Why do some extremely damaged organisms live long healthy lives? Why do some pristine organisms drop dead in the prime of life? Why are all of these aging hallmarks, or forms of damage, that I have listed above, not only found in elderly, decrepit, disease ridden individuals, but also happen to be all found (some to a much greater degree proportionately) in the earliest stages of life in developing embryos and fetuses? We still have an incomplete big picture of aging and that’s no good if we want to truly intervene in it. That’s why I’m so happy that joining us today to take us deeper into this topic, and expose us to some truly fascinating ideas and theory, is Dr. Josh Mitteldorf. After earning a PhD in astrophysics at University of Pennsylvania and spending a decade or so in that field, as well as in the areas of optical design and energy conservation, Dr. Mitteldorf made a move and transitioned into the field of evolutionary biology and currently studies evolutionary theory of aging using various computer simulations. He has spent a lot of time over the years looking to correct what he feels is a fundamental error in the foundations of evolutionary theory where he feels that evolutionary biologists had focused too much on the "selfish gene theory" (the gene-centered view of evolution that purely holds that adaptive evolution occurs through the differential survival of competing genes), and not enough on the ecological context surrounding those organisms and their genes, which he feels has everything to do with why we age and, by extension, what we have to do to stay healthy as we get older. Over the years he has lectured extensively at universities including Harvard, MIT, Berkeley, Bryn Mawr, LaSalle and Temple. He’s the author of two books on the topic including Cracking the Aging Code: The New Science of Growing Old - And What It Means for Staying Young and Aging is a Group-Selected Adaptation: Theory, Evidence, and Medical Implications. He also is responsible for the “Aging Maters / Playing the Game for a Longer Life” blog, which is truly an encyclopedic resource for all things happening in the longevity biotech space. He is also creator of the Data-BETA project, a project conducted in cooperation with the UCLA laboratory of Steve Horvath, to study the synergy of various different supplements and drug interventions, designed to find the rare combinations that work together to produce a big anti-aging benefit. On this show we will hear from Dr. Mitteldorf: About his background and what it is like to be astrophysicist in the world of evolutionary biology and aging. His aging theories. The Data-BETA Project. His other passions including meditation, yoga, music, environmentalism, and campaigning for a smoke-free / tobacco-free world. For the full text with links please visit www.radioideaxme.com. ideaXme is a global podcast, creator series and mentor programme. Mission: Move the human story forward!™ ideaXme Ltd.
Ira Pastor, ideaXme longevity and aging ambassador and founder of Bioquark, interviews Dr. William Pruett, from the Physiology and Biophysics Department, of the University of Mississippi Medical Center. Ira Pastor Comments: The year is now 2019, and we have surpassed $7 trillion in total annual healthcare expenditures around the globe. As part of that $7 trillion, we’re now spending close to a $1 trillion a year on pharmaceutical products. As we’ve been watching the traditional pharma product basket change over the last century, form small organic molecules drugs and vaccines, to larger macromolecule biologics (proteins and antibodies), and now into an era of gene and cell therapies, and other therapeutic modalities, the tools that allow these discoveries and development of these novel interventions have been changing as well. A set of tools that we have been hearing quite a bit about (and that we have discussed a bit on the show) in recent years is the triad of artificial intelligence, machine learning, and deep learning and their respective applications in the drug discovery and development processes. And a term we have heard a lot mentioned alongside these tools is that of “In-Silico” - an expression meaning "performed on computer" or "via computer simulation" in reference to different biological experiments. We’ve talked about a few of these applications on past shows, in terms of using some of these tools to better guide the rational drug design process, or more appropriately select patients for a clinical trial, via personalized medicine. But we have yet to address the "800-pound gorilla" in the room, and that is that even after you have your "perfect" drug candidate and your "perfect" inclusion / exclusion criteria, traditional clinical trials still cost billions of dollars and take many years of hard work, with no guarantee that your new drug will make it through the complexity that is represented by the human body, with its 30 trillion cells, its endless array of heterogenic micro-environments, wide range of gene expression, and so forth. But what if this wasn’t the case in the future? What if it was possible to conduct "In-Silico" clinical trials on virtual bodies that could perfectly mimic human physiology? Today we are joined by Dr. William Pruett, from the Physiology and Biophysics Department, of the University of Mississippi Medical Center. With a Doctorate in Mathematics from Baylor University, Dr. Pruett has been merging his skills from Mathematics (including expertise in representation theory, geometry, combinatorics, numerical analysis and algorithms) with an in-depth understanding of cardiovascular, renal, and endocrine physiology. Dr. Pruett’s research interests include the use of physiological modeling to generate hypotheses and to understand integrative physiological mechanisms that are not observable in either whole animal or human experiments. For almost 50 years, his department has been developing computer simulations of integrative physiology for both research and educational purposes. The current model, HumMod, is comprised of 14 organ systems, and includes neural, endocrine, circulatory, and renal physiology. HumMod provides a top-down model of human physiology from whole organs to individual molecules. It features more than 1,500 equations and 6,500 variables such as body fluids, circulation, electrolytes, hormones, metabolism, and skin temperature. HumMod aims to simulate how human physiology works and is currently the most sophisticated mathematical model of human physiology ever created. On this show we will hear from Dr. Pruett: How he became interested in mathematics, physiology, and in merging the two together. An overview of Hummod and how it works. Hummod's use in understanding renal physiology and pathophysiology of hypertension. Other therapeutic indications he and his partners are working on. Finally, his future visions of In-Silico clinical trials. ideaXme is a global podcast, mentor programme and creator series. Mission: Move the human story forward!™ ideaXme Ltd.
Ira Pastor, ideaXme longevity and aging ambassador and founder of Bioquark, interviews Dr. Per Borghammer, Clinical Professor in the Department of Clinical Medicine, Nuclear Medicine and the Positron Emission Tomography (PET) Center at Aarhus University in Denmark. Ira Pastor Comments: On past shows we have touched on the topic of systems biology, a field of study that looks at the interactions between components of biological systems, and how these interactions give rise to the function and behavior of that system, and the respective biological processes whether that be growth, development, aging, disease, or degeneration. On other shows, we’ve also touched on the microbiome and virome, as well as the connection between various microorganisms, either directly, or via the immunomodulatory and/or auto-immune effects that may occur from being exposed to them, on the downstream development, progression, or in some cases control of chronic diseases such as Alzheimer’s and Diabetes. And lastly, we’ve touched on the topic of “inflamm-aging;” this chronic progressive increase in the proinflammatory status across your body as you get older. Today we are going to continue along at the intersection of these interesting themes in relation to the topic of Parkinson’s Disease (PD). Parkinson's Disease is a long-term degenerative disorder of the central nervous system (affecting an estimated 6 million people globally) that mainly affects the motor system. The symptoms usually emerge slowly, which in early disease typically manifest as shaking, rigidity, slowness of movement, and difficulty with walking, and these main motor symptoms are collectively called "parkinsonism", or a "parkinsonian syndrome." The motor symptoms of the disease result from the death of cells in the substantia nigra, a region of the midbrain which results in not enough dopamine in this region of the brain. The cause of this cell death is poorly understood, but it involves the build-up of proteins (a main one being alpha-synuclein) into abnormal aggregates called Lewy bodies in the neurons. As the disease worsens, non-motor symptoms become more common and thinking and behavioral problems may also occur. Dementia becomes common in the advanced stages of the disease. Depression and anxiety are also common, occurring in more than a third of people with PD. Other symptoms include sensory, sleep, and emotional problems. The cause of Parkinson's Disease is unknown but is believed to involve both genetic and environmental factors. Those with a family member affected are more likely to get the disease themselves. There is also an increased risk in people exposed to certain pesticides and among those who have had prior head injuries, while interestingly there is a reduced risk in tobacco smokers and those who drink coffee or tea. Our guest today is going to take us down the path of a fascinating new theory that in certain cases of Parkinson's Disease, this horrific degenerative CNS disorder, might actually arise not in the CNS at all, but in the intestinal system and from there migrate to the brain. Dr. Per Borghammer, is Clinical Professor in the Department of Clinical Medicine, Nuclear Medicine and the Positron Emission Tomography (PET) Center at Aarhus University in Denmark. With a PhD in Neuroscience and a medical degree from Aarhus, Dr. Borghammer specializes in a variety of Neurobiological research areas including the study of Parkinson's disease, Atypical Parkinson's, and other neurodegenerative brain disorder pathophysiology & imaging, imaging within the parasympathetic nervous system, and imaging of cholinergic signalling processes that occur in other pathologies such as prostate cancer and chronic inflammation. He recently won the European Association of Nuclear Medicine's Marie Curie Award for a project entitled "Visualising Parasympathetic Denervation in Parkinson’s Disease." Today we will hear from Dr. Borghammer: How he became interested in science, medicine, and the intersection of nuclear medicine and neuroscience. The current state of the nuclear medicine research system. When and how the idea arose that PD may start in the gut and how he contributed to this finding. The difference between "brain-first" and "gut-first" PD pathology. What could be the initiating causes of gut-first PD. Finally, how we may bring gut-first PD under control. ideaXme global podcast, creator series and mentor programme. Mission: Move the human story forward!™ ideaXme Ltd.
Ira Pastor, ideaXme longevity and aging ambassador and founder of Bioquark, interviews Dr. Alice C. Parker, Dean's Professor of Electrical and Computer Engineering at the Viterbi School of Engineering, University of Southern California. They talk of Dr Parker's work to build a synthetic brain. Ira Pastor Comments: On the last several shows we have spent time talking to many people working on both "the cutting edge" and "the bleeding edge" as it pertains to the various emerging therapeutic and preventative technologies related to health, diseases and the processes of aging. In doing so we’ve had various guests on who are engineering and building new devices and machines for human enhancement, including bio-artificial hearts, kidneys, bionic prostheses, and exoskeletons. Building a Synthetic Brain Today, we are going to go a bit beyond the bleeding edge of things, into what sounds like science fiction and discuss the topic of "Building a Synthetic Brain." With a Ph.D. in Electrical Engineering for North Carolina State, Dr. Parker specializes in a diverse range of disciplines including biomimetic neuromorphic circuits, biomimetic stereo vision, retinal and cortical neuromorphic analog circuits, and nanotechnology. Dr. Alice C. Parker, who is building a synthetic brain: Dr. Parkerhas served as the Division Director for Computer Engineering, Dean of Graduate Studies, and Vice Provost for Research at USC. Extensively published, Dr. Parker's current research focuses on the Biomimetic Real-time Cortex project based off the National Academy of Engineering's Grand Challenge, "Reverse Engineering the Brain," to explore the questions of if, when and how an artificial brain could be constructed for so-called "whole brain emulation," which includes emulating the complexity of the individual neuronal computations, constructing systems on the scale of the human brain with billions of neurons and trillions of synapses, connecting the neurons for effective and efficient communication, and implementing plasticity, or the ability of the brain to change and grow as learning occurs. On the show we will hear from Dr. Parker: About her background, how she got interested in science, engineering, and this fascinating world of neuromorphic computer design. About the basic approach of the Real-time Cortex Project and the next steps in the research process. Ira Pastor, ideaXme longevity and aging Ambassador and Founder of Bioquark. ideaXme is a global podcast, creator series and mentor programme. Mission: Move the human story forward!™ ideaXme Ltd. Follow @ideaxmon Twitter on Instagram @ideaxme Finally, we’ll gain insight into Dr. Parker’s vision for what these computers could actually be capable of accomplishing in the coming decades and if such computers could exhibit some degree of consciousness. ideaXme is a global podcast, creator series and mentor programme. Mission: Move the human story forward! ideaXme Ltd.
Acts 4:32-37 // II Cor 9:10-13
Acts 4:32-37 // II Cor 9:10-13
What is empowered wellness? How do you relearn to honor and love yourself from a heartfelt space of knowing without viewing it as selfish? Suzie & Sheetal explore the energy behind emotions, judgments, and thoughts. Sheetal shares insight on her transition from the corporate world to the wellness one. Listen to her nuggets of wisdom related to her Mission: Move well. Breathe well. Think well. “We all start out that way- valuing and loving ourselves- and, somehow on our way, we sometimes unlearn it.” About Sheetal: Connect with Sheetal on her website and subscribe to her newsletter www.solunasolutions.com
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