Podcast appearances and mentions of Daniel Goldberg

Daniel Goldberg's journey through the intersection of media and healthcare technology provides a compelling narrative of innovation and adaptation. His career trajectory—from navigating Hollywood's demanding media landscape to pioneering transformative solutions in healthcare tech—underscores the crucial lessons learned at this dynamic intersection. This episode delves into Goldberg's insights and experiences, revealing how his expertise and passion have shaped groundbreaking advancements in both industries.  [00:16] - About Daniel Goldberg Daniel is the CEO of ENGAUGE LLC, a healthcare company. He started his career in film production in Hollywood. --- Support this podcast: https://podcasters.spotify.com/pod/show/tbcy/support

"Stripes" (1981), directed by Ivan Reitman and starring Bill Murray and Harold Ramis, is a quintessential early '80s comedy that perfectly captures the zeitgeist of an era that teetered between the absurdity of the Cold War and the ever-relaxing social mores. At its heart, "Stripes" is a comedic rebellion against the rigidity of military life, making it a film that resonates with the themes of individualism and anti-establishment sentiment prevalent at the time.The Plot & CharactersThe film follows the misadventures of John Winger (Bill Murray), a down-on-his-luck cab driver who, in a fit of existential despair, convinces his friend Russell Ziskey (Harold Ramis), a mild-mannered English teacher, to join the Army with him. Their journey from slackers to slightly less inept soldiers forms the crux of the story. Murray's portrayal of Winger is a masterclass in comedic timing and deadpan delivery, embodying the everyman who finds himself at odds with authority at every turn.Harold Ramis' Russell is the perfect foil to Murray's antics. His subtle and intelligent performance balances the overt slapstick and provides a grounding presence amidst the chaos. Together, they stumble through basic training under the watchful eye of their beleaguered sergeant, played by Warren Oates, who embodies the archetypal tough-as-nails drill sergeant with a secret soft spot for his bumbling recruits.Cinematography & DirectionIvan Reitman's direction in "Stripes" is both savvy and unpretentious. He allows the comedic talent of his cast to shine through, using a straightforward cinematic style that keeps the focus firmly on the characters and their shenanigans. The film is shot with a traditional approach that eschews flashy techniques for steady, well-composed scenes that support the comedic narrative without overshadowing it.Cultural Impact & Relevance"Stripes" came out at a time when America was dealing with the hangover from Vietnam and general scepticism about military interventions. The film taps into this sentiment by portraying the Army as a place where the misfits and the rebels not only fit in but thrive in their ridiculous ways. This subversive undercurrent helped "Stripes" resonate with a generation that was disillusioned with authority, making it a staple of 1980s cinema and a cultural touchstone for discussions about conformity and rebellion.Moreover, the film's influence can be seen in the way it helped to define the comedy genre for the decade. It paved the way for a type of humour that is both irreverent and introspective, giving rise to the careers of its leads and influencing other comedic works that followed.Humour & WritingThe humour in "Stripes" is both overt and subtle, blending slapstick with witty dialogue that mocks the seriousness of military conventions. Bill Murray's irreverent character is constantly skewering the absurdity he encounters, whether it's questioning why any sane person would want to be a soldier or improvising one of his many irrepressible speeches that rally his fellow underdogs to his cause. The script, co-written by Harold Ramis, Len Blum, and Daniel Goldberg, is sharp and full of memorable lines that have entered the pop culture lexicon, like the classic "That's the fact, Jack!"The screenplay also smartly uses its comedic elements to develop its characters, making them more than just caricatures. We see genuine growth in John and Russell, who, despite their initial lack of direction, find something resembling pride and purpose in their service, albeit in their typically unconventional ways. This transformation provides a satisfying narrative arc that balances the film's sillier moments with moments of genuine character development.Impact on Pop Culture"Stripes" also serves as a prime example of how comedy can reflect and influence societal attitudes. Its enduring popularity underscores its effectiveness at capturing the spirit of its time and offering a form of escapism while also providing commentary on real-world issues. The film's legacy can be seen in how it influenced the structure and tone of future comedies, which often adopted its blend of humour, heartfelt moments, and critique of authority.Additionally, "Stripes" is notable for its soundtrack, which complements its comedic and thematic elements perfectly, enhancing the film's atmosphere and reinforcing its light-hearted take on serious matters. The iconic scene of the platoon marching to a non-traditional cadence is just one example of how music and sound play integral roles in the film's appeal.Relevance TodayWatching "Stripes" today, it's fascinating to see how its themes of challenging authority and finding individuality within a conformist setting resonate in a contemporary context. The film speaks to the timeless struggle between personal freedom and institutional demands, making it as relevant now as it was in the 1980s. For new viewers, "Stripes" offers a snapshot of a particular moment in American history, both socially and culturally, while for others, it remains a nostalgic favourite that reminds them of their youthful rebelliousness.Final ThoughtsOverall, "Stripes" is more than just a comedy. It's a culturally significant film that offers a critique of military life through the lens of humour, making serious points about personal autonomy, friendship, and the absurdity of rigid institutions. Its continued relevance and popularity make it a standout film of the 1980s and a significant part of the comedy genre's history.In conclusion, "Stripes" is a must-watch for fans of classic comedy and those interested in a humorous yet insightful look at military life and personal rebellion. Its successful blend of humour, character development, and cultural commentary ensures that it remains an important and beloved film, resonating with audiences and influencing filmmakers decades after its release. Whether you're revisiting it or seeing it for the first time, "Stripes" offers both laughs and a thoughtful reflection on the clash between individuality and conformity, making it a timeless piece of cinema.Please follow the Podcast and join our community at https://linktr.ee/borntowatchpodcast If you are looking to start a podcast and want a host or get guests to pipe in remotely, look no further than Riverside.fmClick the link below https://riverside.fm/?utm_campaign=campaign_1&utm_medium=affiliate&utm_source=rewardful&via=matthew

CORTE EP #92: Luis Stuhlberger e Daniel Goldberg divergem ao falar sobre motivos por trás da saída do investidor estrangeiro do Brasil.

Acompanhou o Macro Summit? Inscreva-se para assistir todos os painéis:https://emprc.us/Geqqmj Luis Stuhlberger e Daniel Goldberg se reúnem pela 1ª vez após anúncio da sociedade entre a Verde a Lumina para falar de mercados, economia e investimentos na live de fechamento do Macro Summit. Convidados: Luis Stuhlberger (sócio fundador e CEO da Verde Asset Management) e Daniel Goldberg (sócio fundador e CIO da Lumina Capital) Apresentadores: Thiago Salomão e Felipe Miranda 

Macro Summit está chegando... já retirou seu ingresso gratuito? Thiago Salomão, Luis Stuhlberger, Daniel Goldberg e outros gigantes do mercado vão revelar as oportunidades de investimentos no cenário atual. Veja como participar do evento:  https://emprc.us/BW1PwN Convidado desta edição, o fundador do Market Makers fala sobre a expectativa para a renda variável no ano após a frustração das expectativas no primeiro trimestre. Entre os destaques da semana, Casas Bahia, Endrick e o Lollapalooza.

Landing a job at the London architecture firm you idolise right out of college is a good sign for any young architect, particularly one from another country. Landing the Great Court at the British Museum as your first project is another. Any architect starting out with these two achievements under their belt would wonder, ‘Where to from here?' Daniel Goldberg is known for his progressive approach to designing from the inside out, with a focus on spatial theory and anthropology. His childhood interests of art and the technical aspects of how things are built have evolved into a wildly successful architectural career focused on the psychology of the way people want to live.  As Founder and Principal at State of Craft – the multi-disciplinary global design studio famous for their integrated approach to architecture and interiors – he's worked on some incredible projects including The Shard residences in London and One Sydney Harbour. He's won the John Barrett Award, was nominated Young Engineer of the Year in 1999 and has had his work published in leading design magazines around the world including Wallpaper, Detail and Architectural Digest.  Listen in as Vince and Daniel discuss what he learnt in his formative years working for Sir Norman Foster, why designing a yacht is akin to designing a small world, and Edward Hall's 1960s science of proxemics spatial psychology theory.  https://www.stateofcraft.co.uk/ See omnystudio.com/listener for privacy information.

Daniel Goldberg is the Chief Creative Director and Co-Founder of MAC Global.MAC Global is recognized as a leader in the live music and live entertainment industry in the Middle East, known for bringing big-name international touring acts to the region such as Ed Sheeran, Michael Bublé, Drake and Sia, among others.Daniel, a former radio announcer himself, joined Kitch and Neeil to reveal the inside word on what it's like to promote some of the worlds biggest acts and the future of live music in Dubai & across the Gulf.https://www.macglobal.com/.Instagram: Dan GoldbergInstagram: KitchInstagram: NeeilInstagram: Producer PranavInstagram: TALK 100.3www.talk1003.ae/. Hosted on Acast. See acast.com/privacy for more information.

As the cooler months approach, we can anticipate a line up of gigs from big artists in Dubai. One artist who is set to rock the Coca-Cola Arena is Bastille. Concert promoter Daniel Goldberg joined me to give us all the exciting details, as well as the upcoming artists lined up. See omnystudio.com/listener for privacy information.

How has social media marketing landscape evolved for orthopedic practices, and where does HopCo fit into this evolution? Join us on this week's episode as we talk to Daniel Goldberg, Senior Vice President of Marketing Communications at HopCo. We discuss how programmatic display and omnichannel marketing strategies are transforming the way orthopedic practices reach potential patients. We also explore how HopCo has seen success with its programmatic ad campaigns and the importance of investing in video assets and building trust with patients. Daniel delves into how video content allows for easier creation and instant access to high-quality content and the implication of having an operational infrastructure in place.  Tune in to learn more about the social media marketing landscape for orthopedic practices! [00:01 - 06:39] Leveraging Omnichannel Strategies with Daniel Goldberg of Hop Co [06:40 - 13:09] How to Increase ROI with Video Assets for Orthopedic Urgent Care [13:10 - 19:47] Maximizing Clicks & Conversions in Sports Medicine with Video Content [19:48 - 26:15] Invest in Operational Infrastructure and Marketing to Grow Your Orthopedic Practice [28:16 - 31:18] Wrapping Up! Want to connect with Daniel? Follow him on LinkedIn, or email him at daniel.goldberg@hopco.com  Key Quotes: "A patient's first interaction with a physician used to be the first time they saw that physician. Now it's the first time they see their video.” - Daniel Goldberg “Those physicians who have high-quality video and have those one-to-one videos where they're addressing patients talking about outcomes, and treatment philosophies, they have a significant advantage over those who don't.” - Daniel Goldberg “You have to figure out what kind of practice you have and what kind of practice you want to build.” - Daniel Goldberg Subscribed Yet? Now you can! Subscribe to the Patient Convert Podcast and never miss a new episode! Subscribe for emails or use your favorite podcast app via Email, Apple Podcasts, Google Play, Spotify, or Stitcher, or visit my website intrepy.com Feel free to connect with me on LinkedIn, Twitter, Facebook, and Instagram.   What We Do Check out our Healthcare Marketing Agency – Intrepy Healthcare Marketing Check out our physician liaison training platform – Physician Liaison University. Leave a Rating & Review for Other Listeners! I hope that you have found this episode and any others you have listened to to be helpful in your growth as a healthcare marketer or practice owner. Please consider leaving a review on one of the channels above. The best way to do that is to rate the podcast on Apple Podcasts and leave us a brief review! You can do the same on Stitcher as well. Your ratings and reviews help get the podcast in front of new listeners. Your feedback also lets me know how I can better serve you. Thanks for listening. Justin & Kelley Knott

In this episode we are joined by Daniel Goldberg, Sr. Vice President of Marketing and Communications at Healthcare Outcomes Performance Company to discuss the most important growth areas for the spine and orthopedic market share. Tune in for strategies on how to make your name stand out and achieve manageable growth.This episode is sponsored by HOPCo.

Garanta sua vaga no SMALL CAPS MASTERS: https://lp1.empiricusinvestimentos.com.br/small-caps-masters-mmk05-0/Daniel Goldberg, um fenômeno do mercado, é um personagem diferente dos que estamos acostumados a trazer no Market Makers. A começar pela formação (direito) e pelo primeiro “emprego” ter sido como secretário de direito econômico do ministério da justiça no Lula 1, entre 2003 e 2006. De lá, foi pro Morgan Stanley Brasil, onde tornou-se presidente do banco. Saiu para criar uma gestora que logo foi comprada pela gigantesca Farallon, na qual ficou por 10 anos. Saiu em 2022 para fundar sua atual gestora, a Lumina, que tem US$ 1,2 bilhão em ativos sob gestão e está em vias de tornar-se sócia da Verde Asset, de Luis Stuhlberger. A longa duração do episódio (3 horas!!) não foi a toa: Goldberg explodiu nossas mentes ao explicar como funciona sua metodologia de focar no “por que investir” ao invés do “no que investir”. Ele explicou ainda por que o ministro Haddad "merece palmas" pelos avanços recentes - mas por que isso lhe tira a preocupação sobre o futuro do fiscal do Brasil -, o que falta para fechar a operação de sociedade com Stuhlberger e qual foi seu grande aprendizado com o desastre do seu primeiro investimento na carreira. Um papo que conseguiu ser único até na recomendação musical ao final da entrevista. Aprecie!Apresentação: Thiago Salomão (@_salomoney) e Renato Santiago (@renatosantiago) Convidados: Daniel Goldberg, fundador e CIO da Lumina Capital Edição: Bianca BarsottiAnuncie no Market Makers: https://sl.mmakers.com.br/mmk03t-conectar/

Analog Jones gets louder and nastier than ever when they review Heavy Metal (1981). Quick Facts Directed by Gerald Potterton Produced by Ivan Reitman and Leonard Mogel (the publisher of Heavy Metal magazine) Screenplay by Daniel Goldberg and Len Blum Based on Original art and stories by Richard Corben, Angus McKie, Thomas Warkentin, Bernie Wrightson Distributed by Columbia Pictures Released Date: August 7, 1981 Budget: $9.3 million Box Office: $20.1 million Rotten Tomato Score: 66% Tomatometer, 67% Audience Score Voice Actors Richard Romanus as Harry Canyon Joe Flaherty as Charlie, the lawyer Eugene Levy as Captain Lincoln F. Sternn Our boy John Vernon (Killer Klowns from Outer Space) as Prosecutor Harold Ramis as Zeke John Candy as Robot and Den - Great to hear his voice again. VHS Description Based on the fantastical illustrated magazine Heavy Metal, producer Ivan Reitman combines original artwork and stories by five of the world's most respected adult animators to create the otherworldly tale of a glowing green orb from outer space that spreads destruction throughout the galaxy.  Richly and lavishly drawn, Heavy Metal includes the science fiction writing of Dan O'Bannon (Alien, Total Recall), the character voices of John Candy and Harold Ramis, and a pounding soundtrack by Black Sabbath, Blue Oyster Cult, Nazareth, and many more.  Highly imaginative and full of surprising special effects. Heavy Metal sets the standard for alternative contemporary animation. An intoxicating experience not to be missed. How to listen and reach Analog Jones and the Temple of Film Discuss these movies and more on our Facebook page. You can also listen to us on iTunes, iHeartRADIO, Podbean, Spotify, and Youtube! Please email us at analogjonestof@gmail.com with any comments or questions!

In today's episode I present you our first Psychedelic Morning Show, Vol.1. A great live podcast collaboration I did with Joe Moore, from Psychedelics Today at the Psychedelic Science conference by MAPS in Denver, this June. To me, it was an incredible joint venture of two podcast. And a community service at a very early time of the day! (We kicked off 7.30 am, like good morning show does!) And we tried to keep it… fun! Trying to talk about drugs, weather and coffee, like you do in a morning show. Our first episode is wild. We had Julie Holland American psychopharmacologist, psychiatrist, and author plus Daniel Goldberg, Co- Founder of the Palo Santo Fund on the show, both famous for their highly entertaining conversations. Plus Melissa Lavasani, Founder and Chief Executive Officer at Psychedelic Medicine Coalition, Founder and President of Psychedelic Medicine PAC and Tracy Tee, founder of Moms on Mushrooms: watch out for their March of Mums in Washington next year. And the great Hadas Alterman, Director of Government Affairs | American Psychedelic Practitioners Association. Please enjoy Volume One! Volume two is one the way in 2 weeks!https://www.palosanto.vc/https://drholland.com/https://www.linkedin.com/in/melissalavasani/https://www.momsonmushrooms.com/https://www.linkedin.com/in/hadasalterman/ Hosted on Acast. See acast.com/privacy for more information.

NISSAN SENTRA | AGENDE SEU TESTE DRIVE:https://www.nissan.com.br/test-drive.html?c020_model=29837?dcp=oth-aon-sntr-aud-nissanaon-t1-cpa-18+-na-non-non-prsen020217901102063304080808129129129020370202343403596-bra-lc&utm_source=oth&utm_medium=ifm&utm_campaign=nissanaon_sntr_aud&utm_term=prsen020217901102063304080808129129129020370202343403596&utm_content=t1-cpa-non-non_aw________________Masterclass Lucros Além da BolsaÉ possível multiplicar o seu patrimônio sem depender só da Renda Fixa e da bolsa. Fred Santoro e Gui Suetugo, em parceria com o InfoMoney, vão te apresentar a estratégia Diversificação 3.0 na masterclass gratuita Lucros Além da Bolsa. Faça agora sua inscrição. Link na Bio!Faça aqui sua inscrição gratuita: http://bit.ly/3Zu8zVz________________Lucas Collazo e Henrique Esteter recebem Daniel Goldberg, CIO e sócio da Lumina Capital Management no episódio ao vivo #189 do podcast Stock Pickers.Daniel atualmente é CIO e sócio da Lumina Capital Management e anteriormente foi Sócio e Head da América Latina da Farallon Capital Management, cargo que ocupou de agosto de 2011 a dezembro de 2021. Foi presidente do Morgan Stanley no Brasil de abril de 2010 a agosto de 2011. Entre janeiro de 2003 e dezembro de 2006, presidiu a área de Direito Econômico Secretaria do Ministério da Justiça, antigo órgão do sistema brasileiro de defesa da concorrência e defesa do consumidor. É bacharel e doutor em Direito pela Universidade de São Paulo. Além disso, ele concluiu um mestrado em Direito pela Harvard Law School.________________EQUIPE DE PRODUÇÃODireção de cortes, produção e edição: Nando LimaProdução: Mariana ShimojoRedes sociais: Rafaella Bertolini

Daniel Goldberg's CredentialsCheck out my podcast: Bits of GoldFind out about a cause I'm passionate about: Experience Camps!Click Here to Schedule A Chat With Me About Sharing Your Story on the Podcast!Click Here to Sign Up For the Weekly Newsletter!The Host's Email

This week on Analog Jones, Chris chooses an excellent Star Wars/Mad Max ripoff in Spacehunter: Adventures in the Forbidden Zone for us to review. We also talk about two TV series House of the Dragon (2022) and Trainwreck: Woodstock '99.  Quick Facts on Spacehunter: Adventures in the Forbidden Zone Directed by Lamont Johson Written by David Preston, Edith Rey, Daniel Goldberg, and Len Blum Story by Stewart Harding, and Jean LaFluer Distributed by Columbia Pictures Release date May 20, 1983 Budget $14.4 million Box Office $16.5 million Starring Peter Strauss as Wolff Molly Ringwald as Niki Ernie Hudson as Washington Andrea Marcovicci as Chalmers Michael Ironside as Overdog McNabb How to find Analog Jones Discuss these movies and more on our Facebook page. You can also listen to us on iTunes, iHeartRADIO, Podbean, and Youtube! Please email us at analogjonestof@gmail.com with any comments or questions!

Daniel Goldberg, Co-Founder and CEO of Bridgement

If you love Heavy Metal (1981) there's a good chance you were going through puberty in the early 80s. Does that check out? Jason Furie and Adam Roth deep dive into this cult classic animation anthology full of bizarre and perverted stories. Did we mention the glowing green orb that embodies pure evil? No? Well that's in there too. And John Candy is in it!Visit Website | Join Newsletter | Support | Facebook | Instagram 

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My name is Jacob Steere-Williams, I am a Historian of Epidemic Disease and Public Health at the College of Charleston. I'll be guest hosting a series of episodes for this special program, but you can catch most of them with the regular host and founder of COVID-Calls, Scott Knowles. My guests today: Nadja Durbach is Professor of History at the University of Utah. She received her PhD from the Johns Hopkins University and is the author of three books on the history of the body in Modern Britain: Bodily Matters: The Anti-Vaccination Movement in England, 1853-1907 (2005), Spectacle of Deformity: Freak Shows and Modern British Culture (2010) and Many Mouths: The Politics of Food in Britain from the Workhouse to the Welfare State (2020). Claas Kirchhelle is Assistant Professor of History (Wellcome Trust University Award) at University College Dublin. His research focuses on the history of microbes, infectious disease control, and the development and regulation of antibiotics and vaccines. He has authored three books on the history of antibiotics in food production (Pyrrhic Progress, 2020 (Rutgers)), animal welfare science and activism (Bearing Witness, 2021 (Palgrave)), and typhoid control (Typhoid, 2022 (Scala)). He is also co-curator of two multi award-winning exhibitions on the history of penicillin (Back from the Dead) and typhoid (Typhoidland). Daniel Goldberg, is an Associate Professor at the Center for Bioethics and Humanities at the University of Colorado's Anschutz Medical Campus. Trained as an attorney, a historian of medicine, and an ethicist, his work is wide-ranging on issues of public health law and ethics, population-level bioethics, the social determinants of health, chronic disease, and pain. Dr. Goldberg has published in virtually every important venue, including the American Journal of Bioethics and the New England Journal of Medicine, and he's been extraordinarily active the past two years in op-eds and interviews about the ongoing pandemic.

The Hangover is a 2009 American comedy film directed by Todd Phillips, co-produced with Daniel Goldberg, and written by Jon Lucas and Scott Moore. It is the first installment in The Hangover trilogy. The film stars Bradley Cooper, Ed Helms, Zach Galifianakis, Heather Graham, Justin Bartha, Ken Jeong, and Jeffrey Tambor. It tells the story of Phil Wenneck (Cooper), Stu Price (Helms), Alan Garner (Galifianakis), and Doug Billings (Bartha), who travel to Las Vegas for a bachelor party to celebrate Doug's impending marriage. However, Phil, Stu, and Alan wake up with Doug missing and no memory of the previous night's events, and must find the groom before the wedding can take place. Follow us on Twitter: https://twitter.com/BreakroomNachos Intro music by Dan Mason: https://danmason.bandcamp.com/

Every year, the Living Sportsgiving episode is all about commemorating our gratitude for strong connections, similar passions, and our memories made over the year. 2021 has been a monumental year for all in the sport industry. Sport is back and firing in all cylinders. In this episode, we are joined with three lovely alumni, Emily Frajdofer, Hannah Schuette, and Daniel Goldberg. Each of them are going to speak to their year in 2021 and what they are thankful for. One consistent lesson that comes from this episode is that building genuine connections, friendships, and relationships can take you far in this industry. This business can be tough…and you need that team behind you in your career. Listen in to hear why.. A warm and special shoutout to all of our alumni that continue to make our community one of the truest and strongest networks you can find in the sport industry. Happy Living Sportsgiving everyone!

This week the boys are back in Vegas with Kelli, Kara and Ryan from Drunk Theory.  We're going to Learn about why Mike Tyson is the real life Tiger King, everything you ever wanted to know about Tasers and counting cards like a pro. Drunk Theory are self billed as a bunch of idiots, drinking and talking about conspiracies. Join them weekly to learn about Crypids, Murders and general drunken nonsense. The Hangover is a 2009 American comedy film directed by Todd Phillips, co-produced with Daniel Goldberg, and written by Jon Lucas and Scott Moore. It is the first installment in The Hangover trilogy. The film stars Bradley Cooper, Ed Helms, Zach Galifianakis, Heather Graham, Justin Bartha, Ken Jeong, and Jeffrey Tambor. It tells the story of Phil Wenneck, Stu Price, Alan Garner, and Doug Billings, who travel to Las Vegas for a bachelor party to celebrate Doug's impending marriage. However, Phil, Stu, and Alan wake up with Doug missing and no memory of the previous night's events, and must find the groom before the wedding can take place. Lucas and Moore wrote the script after executive producer Chris Bender's friend disappeared and had a large bill after being sent to a strip club. After Lucas and Moore sold it to the studio for $2 million, Phillips and Jeremy Garelick rewrote the script to include a tiger as well as a subplot involving a baby and a police cruiser, and also including boxer Mike Tyson. Filming took place in Nevada for 15 days, and during filming, the three main actors (Cooper, Helms, and Galifianakis) formed a real friendship. The Hangover was released on June 5, 2009,[4] and was a critical and commercial success. The film became the tenth-highest-grossing film of 2009, with a worldwide gross of over $467 million. The film won the Golden Globe Award for Best Motion Picture – Musical or Comedy, and received multiple other accolades. It is the highest-grossing R-rated comedy ever in the United States at the time (before its sequel broke the record), surpassing a record previously held by Beverly Hills Cop for almost 25 years.[5] --- Join us on the Socials: Twitter  Instagram  Facebook  Support the show (Buy me a Coffee) 

On episode #54 of The Vine, PMP talks to Daniel Goldberg, a Founder of Palo Santo, an investment fund that is supporting startup psychedelic companies that are purpose-driven and science informed. https://prettyeasypodcasts.com (Produced by Pretty Easy Podcasts)

The future of mental wellness is being built today. Through its diversified investment fund, Palo Santo is positioned to increase the supply of clinically effective, affordable, and accessible mental health and addiction treatment solutions needed in today's world. “Palo Santo is seeing far more unique, high quality investment opportunities than we would have anticipated at this stage of the cycle and is therefore evaluating upsizing this current fund,” said Tim Schlidt, the co-founder of Palo Santo. Palo Santo is a U.S.-based psychedelic investment fund focused on increasing the supply of clinically effective and accessible mental health and addiction treatment solutions needed in today's world. The firm targets a diverse range of companies offering innovative solutions across biopharma, drug development, digital therapeutics, healthcare services, and tech-enabled solutions to address the growing global mental health crisis. The nascent psychedelic treatment market has seen investor demand surge over the last year as multiple studies have shown psilocybin, an active compound in magic mushrooms, is effective in treating depression and other mental afflictions. To date, Palo Santo has partnered with and funded more than 20-plus portfolio companies with notable investments such as atai Life Sciences, neurocare, Reset Pharma, Tactogen, Eleusis, Beckley Psytech, Delix, Bexson Biomedical, Ksana Health, Bright Minds, Psy Therapeutics, and Gilgamesh, among others. The psychedelic fund will be an active participant and work with the managements of the companies it invests in, said Schlidt, a former healthcare banker, in an interview with Reuters. The fund will mainly invest in companies that are in the early stages of their fundraising, but could eventually begin investing in the late-stage rounds as well, co-founder Daniel Goldberg said. He added the fund would also look to invest in companies whose operations go beyond just the production of psilocybin and focus on the development of new compounds based on it or its delivery methods. Guest: Tim Schlidt, Co-Founder & Partner at Palo Santo https://www.linkedin.com/in/tim-schlidt-50538255/ https://www.palosanto.vc/about Host: Josh Kincaid, Capital Markets Analyst & host of your cannabis business podcast. https://www.linkedin.com/in/joshkincaid/ Episode 587 The Talking Hedge: Your Cannabis Business Podcast. ​Covering cannabis products, reviews, business news, interviews, investments, events, and more. https://www.theTalkingHedgepodcast.com Music Info: Song: Dark Trap Beats Hard Rap Instrumental | Gang | 2018Artist: LuxrayBeats Keywords: Hemp News, Weed News, Cannabis News, Marijuana News, Cannabis Business, Marijuana Business, Cannabis Industry News, Marijuana Industry News, Weed News 420, Talking Hedge Podcast, Cannabis Podcast, Marijuana Podcast, Business Podcast, CBD podcast, THC podcast, Cannabis Pitch Deck, Marijuana Pitch Deck, Marijuana Investment Deck, Cannabis Investment Deck, Cannabis Compliance, Cannabis Data, Cannabis Banking, Cannabis Investment, Pot Stocks, Cannabis Stocks, Weed Stocks, Marijuana Stocks, Cannabis Data, Marijuana Data, Cannabis Analytics, Marijuana Analytics, Cannabis Sales Data, Marijuana Sales Data Josh is not an investment adviser. The Talking Hedge is long gold and silver. Listeners should always speak to their personal financial advisers. This is only entertainment.

The future of mental wellness is being built today. Through its diversified investment fund, Palo Santo is positioned to increase the supply of clinically effective, affordable, and accessible mental health and addiction treatment solutions needed in today's world. “Palo Santo is seeing far more unique, high quality investment opportunities than we would have anticipated at this stage of the cycle and is therefore evaluating upsizing this current fund,” said Tim Schlidt, the co-founder of Palo Santo. Palo Santo is a U.S.-based psychedelic investment fund focused on increasing the supply of clinically effective and accessible mental health and addiction treatment solutions needed in today's world. The firm targets a diverse range of companies offering innovative solutions across biopharma, drug development, digital therapeutics, healthcare services, and tech-enabled solutions to address the growing global mental health crisis. The nascent psychedelic treatment market has seen investor demand surge over the last year as multiple studies have shown psilocybin, an active compound in magic mushrooms, is effective in treating depression and other mental afflictions. To date, Palo Santo has partnered with and funded more than 20-plus portfolio companies with notable investments such as atai Life Sciences, neurocare, Reset Pharma, Tactogen, Eleusis, Beckley Psytech, Delix, Bexson Biomedical, Ksana Health, Bright Minds, Psy Therapeutics, and Gilgamesh, among others. The psychedelic fund will be an active participant and work with the managements of the companies it invests in, said Schlidt, a former healthcare banker, in an interview with Reuters. The fund will mainly invest in companies that are in the early stages of their fundraising, but could eventually begin investing in the late-stage rounds as well, co-founder Daniel Goldberg said. He added the fund would also look to invest in companies whose operations go beyond just the production of psilocybin and focus on the development of new compounds based on it or its delivery methods. Guest: Tim Schlidt, Co-Founder & Partner at Palo Santo https://www.linkedin.com/in/tim-schlidt-50538255/ https://www.palosanto.vc/about Host: Josh Kincaid, Capital Markets Analyst & host of your cannabis business podcast. https://www.linkedin.com/in/joshkincaid/ Episode 587 The Talking Hedge: Your Cannabis Business Podcast. ​Covering cannabis products, reviews, business news, interviews, investments, events, and more. https://www.theTalkingHedgepodcast.com Music Info: Song: Dark Trap Beats Hard Rap Instrumental | Gang | 2018Artist: LuxrayBeats Keywords: Hemp News, Weed News, Cannabis News, Marijuana News, Cannabis Business, Marijuana Business, Cannabis Industry News, Marijuana Industry News, Weed News 420, Talking Hedge Podcast, Cannabis Podcast, Marijuana Podcast, Business Podcast, CBD podcast, THC podcast, Cannabis Pitch Deck, Marijuana Pitch Deck, Marijuana Investment Deck, Cannabis Investment Deck, Cannabis Compliance, Cannabis Data, Cannabis Banking, Cannabis Investment, Pot Stocks, Cannabis Stocks, Weed Stocks, Marijuana Stocks, Cannabis Data, Marijuana Data, Cannabis Analytics, Marijuana Analytics, Cannabis Sales Data, Marijuana Sales Data Josh is not an investment adviser. The Talking Hedge is long gold and silver. Listeners should always speak to their personal financial advisers. This is only entertainment. --- Support this podcast: https://anchor.fm/talkinghedge/support

My guests today are Daniel Goldberg and Tim Schlidt, founders of the Palo Santo fund. The two them an their really impressive team got a big plan for the coming years: investing across the new psychedelic ecosystem and funding a new paradigm in well being.Palo Santo's diversified investment fund is helping to increase the supply of clinically effective and accessible mental health and addiction treatment solutions needed in today's world. Daniel Goldberg began seeing mental health as part of a spectrum and not something that needs to be so pathologized.As a founder of Palo Santo and Bridge Investments, Daniel has been actively investing with and supporting inspired entrepreneurs for 20 years. Years ago he saw the transformational potential of psychedelic medicines and has developed a deep network of relationships across the psychedelic research and business communities. His passion for the space is purpose‐driven and science informed. He is thrilled to be a part of Palo Santo's mission of supporting promising treatments while ensuring widespread access to safe, legal, and effective solutions. Tim Schlidt brings extensive knowledge investing across life sciences and healthcare services, and has held a lifelong passion for understanding and improving treatments for CNS disorders. He believes psychedelics are poised to shift the paradigm in mental health treatment and his primary mission in co-founding Palo Santo is to invest in companies and solutions that allow for broad access to those most in need of mental health care. Prior to co-founding Palo Santo, Tim covered the life sciences and health care services sectors as a private equity investor at Madison Dearborn Partners and an investment banker at J.P. Morgan and Greenhill. We talk about Daniels and Tims personal psychedelic experience they had BEFORE the founding of Palo Santo, the shift and the incredible change they saw coming, when a new generation of scientists engaged in psychedelics, about the psychedelic pharma model and what compound is Daniels and Tims favorite and we chat about what will possibly be happening and what I will see, if I would dare to take 5 MEO DMT: but that will happen on the next episode. https://www.palosanto.vc

The past year-and-a-half has brought countless challenges for restaurants, from the early days when restaurant operators were forced to think on their feet as sudden shutdown orders brought dine-in business to a halt, to current struggles with cash flow and vaccinations. During the course of the pandemic, restaurants have had to reinvent themselves countless times - ramping up off-premises sales, exploring virtual brands and rallying around their communities to support people in need. Right now the industry needs those same communities to rally around it. South Africa, like most countries, can't afford for its hospitality industry to fail. With it would go thousands of businesses – cheesemakers, farmers, bakers and winemakers – and millions of jobs. And the hospitality industry in South Africa faces another complication in that it leans heavily on tourism. To talk about what happens next for Restaurants Michael Avery is joined by Grace Harding, CEO Ocean Basket; Catharina Bester, Marketing Manager: McCain Foodservice & Retail; Daniel Goldberg, Co-founder of financier Bridgement

The January 6 Coup Almost Succeeded, Not by the Mob, But the Eastman Memo | The U.S. is Heading For an Authoritarian Electoral Coup to Install a Kleptocracy | Why Are Democratic Moderates Sabotaging Biden's Agenda? backgroundbriefing.org/donate twitter.com/ianmastersmedia facebook.com/ianmastersmedia

As a fonder of Palo Santo and Bridge Investments, Daniel has ben actively investing with and supporting inspired entrepreneurs for 20 years. Years ago he saw the potential of psychedelic medicines and has developed a deep network of relationships across the psychedelic research and business communities. His passion for the space is purpose-driven and science informed. He is thrilled to be a part of Palo Santo's mission of supporting promising treatments while ensuring widespread access to safe, legal, and effective solutions.

Welcome back to the special episode of the Paradox Podcast!Today one of our co-hosts, Daniel Goldberg discusses the circumstances of his departure from our company with Shams Jorjani!We talk about what happens when a senior level manager leaves and what impact – good and bad – is felt in the company.0:15 – Intro1:58 – What we've been playing11:36 - What happens when a high-level executive leaves the company?15:57 - How do you hand over the leadership role?21:46 – Is there anything to worry about or hope for?28:11 – How is the “Lame Duck” period like for the departing executive?29:36 – Daniel's goodbyes and what's next for the podcast?You can also find today's episode on: • Spotify: https://pdxint.at/2HFshtu​• iTunes: http://pdxint.at/2BnBWBo​• Player.fm: http://pdxint.at/2EWTCnl​• Poddtoppen: http://pdxint.at/2CiqXGw​• Acast: http://pdxint.at/2ExBD9lWelcome​The Paradox Podcast is now back in a bi-weekly schedule! Join us in 2 weeks to meet Shams' new co-host!Support the show (http://paradoxplaza.com)

On today's podcast, we learn important lessons on resilience and living out your dream in a life that's full of ups and downs. Co-Founder of MAG-Sourcing and host of the Bits of Gold Podcast, Daniel Goldberg, shares his awe-inspiring experience with tragedy and fulfilling the journey to personal purpose that follows. “You cant control how much time you have on this earth. The only thing you can control is how you spend the limited time you are given.” ⏳ Tune to learn more about how we can all lead our lives with fullness and vision.

On this episode of Mushroom Talk, we have Tim Schlidt joining us to chat about the role that venture capital plays in the psychedelic space. We dive deep into what he looks for in a founder and company when he is investing, and his story coming out of the psychedelic closet. One important note that we discuss are his thoughts on the corporatization of plant medicine, specifically the role of patents. Tim is a mover and shaker in the VC Psychedelic space bringing us a ton of knowledge, wisdom, and guidance on finance and psychedelics. About Tim:Years ago, co-founders Tim Schlidt, Daniel Goldberg, and Tony Eisenberg saw the enormous therapeutic potential psychedelic medicines posed. After years of researching and networking in the space, they co-founded Palo Santo in 2020 to focus on investing across this emerging ecosystem of psychedelic healthcare companies. As a former investment banker and private equity investor active in the life sciences and healthcare services sectors, Tim brings extensive experience evaluating healthcare deals and offers a unique perspective to the nascent sector of psychedelic-focused biopharma Hosted on Acast. See acast.com/privacy for more information.

Another great week, another great dad – Coach Randy and Adam D welcome Daniel Goldberg, Senior Vice President, Corporate Development with Lavvan – a reliablyContinue reading

Directed by Ivan Reitman (his first major motion picture)Written by Len Blum, Daniel Goldberg, Janis Allen, and Harold Ramis (Egon from Ghostbusters)Starring Bill Murray (in his first starring role), Harvey Atkin, and Kate Lynch.Released June 29, 1979.Budget of $1.4M ($5M in 2020)Box Office: $43M ($154M in 2020)Gross: $4.16M ($149M in 2020) At one time was the highest grossing Canadian film in the United States and Canada.Rotten Tomatoes: 72%IMDB: 6.2/10Bill Murrays costume were his own clothes.First of 6 collaborations with Harold Ramis in many roles, the others being Stripes, Caddyshack, Ghostbusters 1 & 2, and Groundhog Day.Filmed at an actual, working summer camp, Camp White Pine in Ontario.Plot:We open at Camp North Star, a cut-rate summer camp. Tripper giving a silly wakeup announcement. It cuts to an obviously boring, monotonous meeting. The old 80's trope of the nerdy head guy, and the cool counselor (Bill Murry, Tripper). Showing the kids loading the busses, we're introduced to Rudy, Spaz, and the rival summer camp, Camp Mohawk.SW: The ending of the announcements prepped me for this movie, Bill Murray flushing the toilet. The intro montage is SUPER 70's/80's campy. At the busses, some terrible acting. How old are the girls talking about getting smokes, 12-13? Hope it gets better. Funny stuff BM says to the reporter, stalk and kill a bear, sexual awareness week. Annoying theme song, kids screaming, “are you ready for the summer”The next few scenes are a lot of exposition; the first day at camp, establishing a social pecking order. Shows the viewer all the various cabins fromthe young children to the “jail bait” cabin. They move to lunch where the director is trying to talk, but the kids don't want info, they want gossip, sothe a girl stands up and shares the gossip with everyone, ending with Wendy being everyones wet dream. An intracamp soccer game, establishingthe relationship between Tripper and Rudy occurs.SW: First day: nerd kid unzipped pants. In the young kids cabin, the councilor shows compassion with the dead frog, surprising. Jailbait cabin is funny. Soccer game, sad kid is sad. The office scene: wow, sexual harassment much?Candace "kidnaps" Crockett in a speedboat and confesses her feelings for him. Tripper starts “Operation Late Night Excitement” gag. Parents dayoccurs, Tripper and Rudy continue to develop their relationship. Spaz and Fink sneak under the girls cabin, which hilariously backfires when thegirls catch them and pants Fink. There was a rivalry basketball game between North Star and the Mowhawks, which the mowhowks dominated.SW: The kidnapping was kinda funny. Bill Murry and the card game, showing his councilor heart of gold. During the “Operation Late Night”, Hardware was sleeping in his tool belt, kinda silly. Taking the guy from is cabin is so campy and unrealistic. But I get the joke. Parents Day: How long have these kids been there? A week? Why is the Nerd Guys dad there, he's a councilor in training. Sad kid is sad his dad didn't come. Nerd Guy and Fat Guy sneak under the girls cabin and OF COURSE they're talking about sex. Classic pants up the flag pole. Do like the classic gag of moving the sleeping director. Basketball game: Mowhawks are still rich assholes. Pantsing the other team: classic 80's power move. Tell story of pants kid in middle school.There is a dance where all the councilors are trying to get laid, then all the CITs go on a camping trip with Trapper. The climax is the annual rivalolympiad against the Mowhawks. On day one, Mowhawks dominate, but cheat also. Down, but not out, Trapper gives a rousing speech about how,“it just doesn't matter!” On the second day, their fates turn around, Fink wins the hotdog contest against the stomach, Spaz carries the tea cups,and Rudy wins the race. They end with a nice campfire and showing Trapper and Roxanne deciding to live together, and riding off on a motorcycle.Closes with one last gag of Morty being left floating in the lake.SW: Bill Murray was creepy with Roxanne at the dance. When they leave for the camping trip, giving sad kid responsibility and visibility. If all the CIT's are camping, who's watching the kids? Like the “ghost” story by the fire. Heard it before. I can't believe Roxanne slept with him after how creepy and forceful Tripper has been. Sad kid is still sad. Olympiad: Mowhawks are assholes, consistency is key. How Tripper mentions east and west Germany. North Star ALSO cheated to win, the fish down the swimsuit. Congrats to Nerd guy, and Fat Guy for finally winning one. Of course, it's up to sad kid to save the day… and does. The Run was weird, seemed like it needed music. ENDING: Sad kid is happy now, made friends. Like the North Star CIT song, felt genuine. Like the last Morty gag on the lake.BIG takeaway: Why is a 29 year old man, the head canceler at a summer camp? Isn't that a bit fucking weird?

Daniel Goldberg is a medical historian, a public health ethicist, a lawyer and has practiced BJJ for 8 years. It was great to have him on the podcast to talk about the course of the Covid-19 pandemic and when we might be able to get back to normal.   00:50 - Introduction to Daniel Goldberg 06:09 - On the difficulty of persuading the unpersuadable 08:02 - How the current pandemic has many historical precedents 12:20 - Vaccine distribution in the USA 19:30 - What happens when everyone make individual choices during a pandemic 22:30 - Why have black, indigenous and latino communities have been rampaged with the virus? 27:45 - Covid-19 vs the Spanish flu 36:15 - Conspiracy theories about Covid-19 and where does distrust of experts come from 44:40 - How to talk to a covid denialist 1:00:20 - Politicians jumping to the front of the vaccination line 1:05:20 - Long term effects of Covid-19 1:12:30 - The BJJ community and Covid-19 1:17:10 - Would paying people to stay home really have worked? 1:25:00 - When might we all return to jiu-jitsu?  

This is a repost from 2018, an article caled Wired Into Pain: a history of the science of pain. I hope you enjoy it. I’ve also recorded an audio version to go with it!I am a Physiotherapist. Almost every person I see in clinic is in pain, and most already have an idea about what has caused their pain. If they are old enough, they might say ‘overuse’, or ‘wear and tear’; if they are younger, they might say ‘bad posture’ or ‘tight muscles’; if they have had a scan, they might say a ‘slipped disc’ or a ‘bone spur’. We accept these explanations prima facie. We consider pain to be a readout on the state of the body’s tissues. Or, as one doctor wrote in 1917, it is “the unerring medical compass that serves as a guide to the pathological lesion”.But it is only very recently that we have come to understand our aches and pains in this way. Since medieval times, until surprisingly recently, people commonly understood their pains in terms of their relationship to God, often as punishment for sin. Physical and emotional pain were entangled, along with mind, body and soul. This was the grim logic of medieval torture and self-flagellation: the truth of the soul could be accessed through the pain of the body.But, as historian Joanna Bourke records in her book The Story of Pain, this mixture of mind, body, soul and God also allowed people to feel pain as comforting: a “vigilant sentinel […] stationed in the frail body by Providence”, as one writer put it in 1832. For others, pain was redemptive: take, for example, the early nineteenth-century labourer Joseph Townend, who resolved himself to God after undergoing surgery without anaesthetic, and reflected at the end of his life on his “sincere thanks to the Almighty God” for his agonising conversion.Pre-modern physicians had a different perspective. Most understood pain according to humoural theory. Hippocrates and his disciple Galen considered all illness to be caused by an imbalance of the body’s humours — phlegm, yellow bile, black bile and blood — which ebb and flow in response changes in the body or its environment. This notion endured for many centuries. To one 18th century writer, pain was a consequence of “viscid blood [stopping] at every narrow passage in its progress”; to another, it was a “Nature throw[ing] a Mischief” about his body. Humoural theory is pre-scientific and seems quaint to us now. But, as Bourke points out, it accounts for an abundance of influences, from our personal temperament and our relationships to the alignment of the planets above our heads, on the pain that we feel.Over the coming centuries, at great cost to people suffering from pain, this insight was lost. This is the story of that loss; of how we arrived at the strange, wrong idea that pain is a straightforward “guide to the pathological lesion”; and of how an emerging re-understanding of pain shows us that it is more complex and more astonishing than we have thought for centuries.Descartes, dualism and the labelled line“The ghost in the machine” — Gilbert RyleIt is in the sixteenth century that we find the beginnings of the dominant modern understanding of the body and its pains. The rise of Protestantism and, amongst secular thinkers, of humanism, contributed to an increased focus on the individual and an understanding of the body as a natural, rather than a supernatural entity. Medicine became more interested in anatomy and the physical laws of nature. Vesalius published his On the Fabric of the Human Body, a compendium of illustrations of dissected cadavers based on the author’s strict, first-hand observations at a time when doctors were not accustomed to performing their own dissections. Later, physicians like William Harvey took principles from physics and astronomy to show that in many ways, our bodies can be understood as machines: pumps, pulleys and levers. Slowly, the body became less sacred and more scientific.It was in this spirit that, in 1641, the French polymath Renes Descartes published his Meditations on First Philosophy. This work contains a drawing that became the seminal image of pain for the next three hundred years. The picture shows a kneeling boy with one foot perilously close to a small campfire. The heat of the flame sends a signal (an “animal spirit”) up a channel to the boy’s pituitary gland, which Descartes reckoned was the seat of consciousness. There, the signal elicits pain, “just as pulling one end of a cord rings the bell at the other end”.This picture makes sense to us, it seems intuitively correct. But this is because in matters of pain we are most of us now, in the Western world at least, the children of Descartes. For pain scientists on the other hand, who have fought in recent decades to emancipate themselves from Descartes, this picture has has come to represent the original sin, the first big lie of the Western world’s understanding of pain.It’s crimes are twofold. First, it is the essence of an idea called dualism, which holds that mind and body are separate. The body feels pain, and passes this information on to the mind. For Cartesian dualists, the body is a machine and we are a kind of ghost in the machine, receiving information about its status.Second, the picture represents pain as being felt by a specific detector in the body, and passed up a specific pathway, the long hollow tube, to a specific location in the boy’s brain. Pain detectors, at the end of a pain pathway, that leads to a pain centre. This idea is called specificity theory, but in this post I’m going to use the term labelled line theory because although it is less common, I think it is more descriptive — a labelled line for pain.As it happens, Descartes’ idea was more subtle than the picture and its subsequent interpretations made out. In his defence, the historians Jan Frans van Dijkhuizen and Karl A.E. Enenkel point out that Descartes knew that pain is not merely perceived, like a mariner perceives his ship, but felt, as if the mind and body are “nighly conjoin’d […] so that I and it make up one thing”. Descartes knew that we don’t just have a body; we are a body. But this subtlety was lost: the picture of the little boy with his foot in the fire has a memetic power that has carried it, along with dualism and the labelled line, through the centuries.The nineteenth century“Nothing less than the social transformation of Western medicine” — Daniel GoldbergThis change came gradually. It was not until the nineteenth century, two hundred years after Descartes’ Meditations, that dualism and the labelled line for pain finally established their authority in medicine.They set in as part of a wider change in the history of medicine following the French Revolution that is sometimes now called the ‘Paris School’. The physicians of the Paris School transformed large teaching hospitals in the city to dedicate them, for the first time, to furthering scientific knowledge through rigorous observation of patients and cadavers, and the classification of disease. They explicitly rejected humoural theory, which held that illnesses are processes that are distributed around the body through the movement of viscous humours. Rather, physicians of the Paris School considered diseases to be the result of lesions localised to a single, solid organ.Influenced by the Paris School, Victorian physicians across the Western world began to search their suffering patients’ bodies for a local, solid lesion to blame for their pain. As one New York physician wrote in 1880, “we fully agree that there can be no morbid manifestations without a change in the material structure of the organs involved”. For the first time, doctors began to think like detectives on the hunt for the smoking gun, following clues provided by the body and its sensations (it is no coincidence that Arthur Conan Doyle was a doctor before he wrote the Sherlock Holmes stories, or that he made his character Watson one, too).This approach has tremendous diagnostic power. But, as we will see, even modern researchers find that our pain, particularly our chronic pain, resists reduction by detective work. How did Victorian physicians respond when their investigations failed to turn up a local lesion to explain pain? According to historian and medical ethicist Daniel Goldberg, many doubled down, hunting for anything they could find. As one surgeon put it, “any lesion anywhere in the body will do to account for an otherwise inexplicable pain”. And that meant any lesion: the surgeon Joseph Swann, or example, baffled by a woman’s 11-year history of pain in an apparently healthy knee, eventually attributed it to an imperfection he found, after much searching, in a nerve in her hand.Those that could not find a lesion anywhere explained unexplained pain as one inevitably must if one subscribes to the logic of dualism: if it’s not in the body, it must be in the mind. Goldberg tells the story of the surgeon Josiah Nott who, in 1872, took on the care of an American soldier whose leg was crushed in a railway accident. The leg had already been amputated by another surgeon at a point about halfway up the calf, but the soldier had developed phantom limb pains. The original surgeon, assuming there must be a local lesion at the end of a labelled line, had then amputated the stump, but to no avail. Nott, making the same assumption, took still more from the stump the next year, and still the patient felt no relief. Later that year, Dr. Nott operated again, removing tissues from three major nerves in the shank. This pattern continued until Nott had removed the poor soldier’s leg up to four inches above the knee, and his sciatic nerve up to the pelvis. When the patient’s pain returned after this final operation, Dr. Nott reasoned that he must have acquired an addiction to opioids which was inciting him to malinger (to exaggerate or feign his disease). Nott had, horribly literally, followed the assumed cause of the disease up a labelled line through the body and, not catching it, decided it must therefore be in the mind.This logic played out on a broad scale in physicians’ understanding of the now-forgotten condition “railway spine”, the widespread and mysterious back pain felt by the victims of train accidents. Initially, physicians thought that the trauma of a crash caused compression of nerve filaments that in turn caused pain. But as time wore on and their investigations repeatedly failed to find a tissue lesion to explain railway spine, even in cadavers, their suspicion grew that railway spine was not a ‘real’ condition at all. After all, weren’t most victims also seeking compensation from railway companies? By the beginning of the twentieth century, railway spine was known instead as “hysterical spine […] merely a psychical condition”. Dualism dictated once more that if we can’t find it in the body, it must be in the mind.1900 to 1965Anomalies, non-anomalies, and opening the gateAnomalies“[Pain] reveals only a minute proportion of illnesses and often, when it is one of their accompaniments, is misleading. On the other hand, in certain chronic cases it seems to be the entire disorder which, without it, would not exist.” — Rene Leriche, 1937The break from Cartesianism began at the end of the nineteenth century, when the great neuroscientist Santiago Ramon y Cajal showed that our nerves, spinal cord and brain are not one thing but composed of many smaller things (which came to be called neurons) linked by gap junctions (which came to be called synapses). Decades earlier, the English neuroscientist Charles Bell had suggested that the function of the nervous system is less straightforward than the labelled line in Descartes’s picture, and Cajal’s work was proof.As we can see by his extraordinary drawings, Cajal meticulously mapped the peripheral neurons in our arms and legs, running to the spinal cord, and the neurons running up the cord, and many of those in our brain. But, according to pain scientist and writer Fernando Cervero, the terminus for incoming peripheral neurons, the foremost part of the spinal cord that we now call the dorsal horn, was so dense and chaotic that it resisted even Cajal’s fastidious eye. He called the dorsal horn a maremagnum, a Spanish word that means ‘confused and disorganised crowd’, as in the bustle of a busy railway station. Cajal’s vision of a network of individual cells, with nodes of incomprehensible complexity, opened up the possibility that signals aren’t simply passed upwards in a linear fashion as Descartes had assumed, but are modulated along the way.The idea that inputs to the nervous system are modulated before they ‘become’ our sensations hints at an explanation for the odd persistent pains for which Victorian physicians could find no lesion. It also begins to explain the opposite phenomenon, lesions that cause no pain, which became unignorable during the brutal first decades of the twentieth century. Doctors like Rene Leriche, on the front line in the Great War, found that soldiers with dreadful wounds often felt no pain and could undergo surgery without anaesthetic. Leriche knew this was not willpower but “certain movements of the hormones, or of the blood”, a presciently non-Cartesian thought.During the Second World War, the American anaesthesiologist Henry Beecher built on Leriche’s observations by conducting a more methodical study at his post in Italy. He found that as many as three quarters of wounded soldiers felt little pain at the time of their injury. As one doctor put it, it was as if wounds and diseases “carry for the most part — most mercifully — their own anaesthetics with them”.One might think that such cases would have alerted the scientific community to the fact that our nervous systems are doing something more than passively relaying pain into our brains, as labelled line theory implied. But for scientists and doctors at large, anomalies that defied labelled line went on hiding in plain sight, “discovered” periodically and then easily forgotten as they had been in the Victorian era. Phantom limb pain, for example, was unignorable during the American Civil War, and then slipped once more from popular consciousness. The doctor and writer Oliver Sacks called these periods of forgetting scotoma, dark gaps in the scientific awareness in which the prevailing theory cannot explain common phenomena and instead shoves them in the attic to think about another day. The progress of science, wrote Sacks, is faltering and haphazard, “very far from a majestic unfolding”.Non-anomalies“Pain is the physiological adjunct of a protective reflex” — Charles Sherrington, writing in 1900“Pain remains a biological enigma — so much of it is useless, a mere curse” — Charles Sherrington, writing forty years later.(Quoted in Understanding Pain by Fernando Cervero)Rather than explaining anomalies, scientists studying pain at the beginning of the twentieth century focused on a series of discoveries that appeared, at first, to confirm labelled line theory. The British neuroscientist Charles Sherrington had coined the term “nociceptor” for the neurons that convey danger messages (elicited by things like heat, intense mechanical pressure or an incision to the skin) to the brain, and in the following decades researchers slowly but successfully identified and isolated these cells.Starting in 1912, American scientists performed the first anterolateral cordotomy, slicing through the part of the spinal cord that was theorized to carry danger messages to the brain and appearing to stop pain in its tracks. Later, the success of such operations would prove to be temporary, but the procedure did show that this part of the spinal cord houses Sherrington’s nociceptors. In 1927, the Americans Herbert Gasser and Joseph Erlanger established that different nerve fibers conduct signals at different velocities, and classified them according to their diameter as A, B and C fibers. A fibers were widest and conducted signals the quickest; C fibers were the most narrow and slow. They found that one sub-type of A fibers, A-delta fibers, conducted the relatively quick sensation of dull pain we feel when we stub our toe; and that C fibers conduct the slower, stinging pain that arrives later. Again, this neat distinction would later prove to be more complicated, but the discovery was further evidence for a labelled line of pain. Gasser and Erlanger were only able to look at conduction signals from a whole bundle of nerves and so it was not until 1958 that Ainsley Iggo was first to record individual A-delta and C fibers and isolate Sherrington’s nociceptors for the first time.Opening the gate“It may seem easy, but it was not” — Ronald MelzackDespite this series of discoveries in favour of labelled line, some researchers could not shake from their minds those confounding anomalies: pain without lesion, and lesion without pain. And so, at last, the science of pain began to wake from its scotoma. Some scientists began to propose a theory to compete with labelled line called pattern theory, which held that it is not the stimulation of specific nerves that causes the sensation of pain, but that the way in which nerves are stimulated, spatially and temporally. Pattern theory was vague, and had nowhere near the amount of evidence that supported labelled line theory, but it did hint at an answer to some of the anomalies that had been documented in the recent scientific literature, such as the way pain spreads beyond the site of an injury and the way rubbing a pain can make it temporarily feel better. Pattern theory was taken up in Oxford in the 1940s and 50s, where the brilliant British neuroscientist Pat Wall was beginning to develop ideas he would turn into gate control theory, a whole new model of pain.In 1959, Wall moved from Oxford to the Massachusetts Institute of Technology where he met Ronald Melzack. Melzack, a Canadian, had just arrived at M.I.T. to take up a post as assistant professor of Psychology, and found to his annoyance that he could not perform research on animals in the university’s Psychology building. So, Melzack decamped to Wall’s lab. The two quickly took up a discussion on the inadequacy of Cartesianism and decided to come up with a new theory to “entice spinal-cord physiologists away from [labelled line]”.From his previous research, Melzack knew the brain sends messages down the spinal cord to inhibit the messages coming up it, exerting a kind of ‘top-down’ control on incoming information. From his own experiments, inspired by pattern theory, Wall knew that different inputs into the nervous system are weighed against each other somehow in the spinal cord, competing to be ‘sent up’ to the brain. Despite their discussions, Melzack and Wall’s ideas remained inchoate until, in 1962, Melzack stumbled on the Dutchman Willem Noordenbos’s pattern-theory hypothesis that large A-fibers carrying touch signals might somehow inhibit small C-fibers carrying danger signals.Melzack calls this moment a “flash of insight”. Noordenbos had theorized that this modulation happened in the substantia gelatinosa, which is part of the terminus for incoming information at the spinal cord. Wall knew that large fibers and small fibers entered the substantia gelatinosa at opposite ends, and theorised that it was this setup that allowed the one to inhibit the other, like closing a figurative ‘gate’. The weight of signals from large and small fibers would determine what kind of message was allowed up to the brain.In 1963, Melzack moved to McGill University in Canada, but travelled South over the border when he could to visit Wall’s home in Boston where, over large amounts of duty free whiskey, the two put the finishing, definitive touches to their work. Their theory differed critically from Noordenbos’ because they proposed that the brain itself plays a role in processing at the substantia gelatinosa, by sending signals down the spinal cord to make the ‘gate’ more likely to open or close to danger signals. This was gate control theory.For the first time, science had a model that began to explain pain anomalies. According to gate control theory, for example, the brain of a soldier who has sustained an injury can send messages down the spinal cord to close the gate to incoming danger signals. Over fifty years have passed, and gate control theory has turned out to be wrong in lots of little ways, but right in one big way: it is modulation in the spinal cord and the brain, or the central nervous system, that explains why pain is so rarely the reliable sign of tissue status that Victorian scientists assumed it was.Neuromatrix theory“We need to go… to the brain” — Ronald Melzack“When you feel a pain in the leg that has been amputated, where is the pain? If you say it is in your head, would it be in your head if your leg had not been amputated? If you say yes, then what reason have you for ever thinking you have a leg?” — Bertrand RussellGate control theory was a great advance but Melzack and Wall knew their theory was incomplete. According to Oliver Sacks, it is by studying anomalies — phenomena not explained by the prevailing theory — that researchers wake from scotoma and begin revolutions in scientific understanding. So it was that Melzack’s interest in the anomaly of phantom limb pain led to neuromatrix theory, the next great boost that finally allowed pain science to escape to orbit of CartesianismIf people without limbs have phantom pain, Melzack reasoned, it follows that the origins of the pattern of pain lie not in the limb but in the brain. And not only pain, but the sensation of having a body in its entirety — its place in the world, its shape, its movements — is housed, in what Melzack came to understand as a series of loops and patterns of neurons, inside our brains. This brain architecture is the neuromatrix.Incoming information, then, is not what holds the essence of our sensations; it merely triggers the neuromatrix, already inscribed in the brain, to ‘produce’ the sensations we feel. If a boy puts his foot in a fire, the nerves do not tell a passive brain “here is pain”; the nerves simply say “here is an intense input”, and the neuromatrix does the rest.How do we get a neuromatrix? Melzack says it is inborn, but then shaped by experiences. So, your neuromatrix develops your own personal signatures for familiar pains, like the pain you might feel in your back when you bend. Crucially, the neuromatrix uses our thoughts and emotions to generate our sensations, as well as sensory information. This makes sense: think of a stroke on the leg from your partner and one from an unappealing stranger. The same sensory input feels different.So, if you believe the cause of your back pain is something threatening, like a suspected spinal cancer or a ‘slipped’ disc, it willfeelworse than if you believe it is something benign, like a muscle strain. If a conscripted soldier sustains a battlefield injury that means he will likely have to leave the trenches to convalesce behind the front lines, that wound may not feel as bad as it would for a factory worker, for whom it could mean a loss of livelihood. If you have just been made redundant, or become divorced, than the incoming danger signals from an incipiently arthritic hip might suddenly start triggering your neuromatrix to produce a deep aching pain in your joints.Pain is intimately integrated with meaning, and informed by the broader context of our lives. And there is no labelled line: pain is the output of a widely-distributed neural process that takes input from countless biological, psychological and social factors.The sensitive nervous system“Not under conditions of my choosing / Wired into pain / Rider on the slow train” — Adrienne RichResearchers have used the neuromatrix as a foundation to develop our understanding of pain. For example, towards the end of the 1970s, scientists began to establish that the endings of our danger messenger neurons, the ones Sherrington christened nociceptors, become more sensitive the more they are used, a process called peripheral sensitization. But perhaps the most remarkable development since Melzack proposed the neuromatrix was Clifford Woolf’s discovery of central sensitization.On completing his medical training in South Africa in the early 1980s, Clifford Woolf joined Pat Wall’s laboratory in London. He was not content with measuring the readouts from individual chains of neurons, and instead began to monitor broader bursts of activity which he thought would give him more insight into the pain system as a whole. He started to measure the output of the neurons that cause muscles to flex away from a dangerous stimulus (think of touching a hot stove and retracting your hand before you are even conscious of pain). Investigating on rats, he found that most of these cells responded to dangerous stimuli, such as heat and pinch, in a fairly narrow field — say, one toe. But, some cells had a very wide receptive field and would respond to even light, non-dangerous touch. Why would rats have neurons designed to elicit a withdrawal response to light touch?It took Woolf some months to realise that he was only finding these neurons at the end of the workday, when his rats had already been subjected to hours of pain-inducing stimuli. He calls this his “eureka moment”. He had not discovered that rats have certain neurons that are super sensitive across a wide receptive field: he had discovered that a rat’s nervous system becomes super sensitive across a wide receptive field when it has been exposed to prolonged danger. Woolf had discovered an ‘amplifier’ mechanism in the spinal cord. This phenomenon is central sensitization.Woolf was the first person to show that the nervous system is not hard-wired for pain but plastic. Prolonged nociception can change the behaviour and the architecture of the nervous system so that non-dangerous inputs (like light touch) are felt as painful, and dangerous inputs (like a pinprick) produce more pain than they otherwise would have done. To top it off, this whole pain experience also spreads beyond the original site of injury. The great physiotherapist Louis Gifford described central sensitization as like tapping X on your computer keyboard three times, and 10 X’s of different sizes and colours popping up on the screen.A mild and benign form of central sensitization is common and almost immediate after most injuries — after you burn your hand or sprain your ankle, it is your body’s way of protecting itself. But central sensitization can wear on and, in many cases, persist and get worse long after any injury has healed. If you or someone you know has widespread back pain that flares up with the slightest movement, or has osteoarthritis in their hip that seems to spread all the way down their leg, they might have central sensitization.Central sensitization can affect many different functions, not just pain. People with ongoing, maladaptive central sensitization can be tense and forgetful, and sensitive to bright lights, loud noises and chemicals. It is also a feature of irritable bowel syndrome, migraine and chronic fatigue syndrome, and often goes hand in hand with anxiety and depression.So long, labelled line: Grappling with complexity“Pain cannot easily be divided from the emotions surrounding it. Apprehension sharpens it, hopelessness intensifies it, loneliness protracts it by making hours seem like days. The worst pain is unexplained pain” — Hilary Mantel“The basic idea of pain modulation implies that the output can be different to the input at every stage in the transmission of pain signals throughout the brain” — Fernando CerveroCentral sensitization is just one discovery that has enhanced our understanding of pain. There are many more examples. Descending modulation is the ongoing process by which the brain sends signals down the spinal cord to simultaneously inhibit and facilitate incoming danger signals, a mechanism Leriche anticipated when he observed that battlefield wounds “carry […] their own anaesthetics with them”. In people with persistent pain, descending modulation may be set for a net facilitation of incoming danger messages. Researchers have also expanded our understanding to include the immune system, which aids and abets the nervous system as it produces pain. They have found out that nociceptors, far from lying waiting for an intense stimulus as Sherrington imagined, are actually firing regularly throughout the day, every time we use a pair of scissors, ride a bike or go on a long walk, without (if we are lucky) our neuromatrix producing the experience of pain. Conversely, clever experiments have shown that nociception is not even necessary for pain, giving credence to the stories of people who narrowly escape injury but, believing they have been hurt, writhe in agony. And, we know that stress, even the stress of early life events, plays a vital role in ongoing pain, and that our stress system and pain production system are intimately linked.The contrast between the byzantine, distributed complexity of the mechanisms of pain and the singular experience of pain — I feel it here — is remarkable. Scientists have made various attempts to simplify the mechanisms into something more understandable and more useful to lay people. The neuroscientist VS Ramachandran has said that “pain is an opinion on the organism’s state of health rather than a mere reflective response to an injury”, a stark contrast to the old-fashioned idea of pain as “the unerring medical compass that serves as a guide to the pathological lesion”.The scientists and physiotherapists Dave Butler and Lorimer Moseley put it elegantly:“We will experience pain when our credible evidence of danger related to our body is greater than our credible evidence of safety related to our body. Equally we won’t have pain when our credible evidence of safety is greater than our credible evidence of danger.”In other words, pain is not measuring damage, it is a protective strategy, just one of many (along with local and systemic inflammation, changes in movement like tensing or bracing, the feeling of stiffness, and so on) that the body enacts in response to credible evidence of danger.This evidence of danger often includes nociception (signals from tissue damage), but the neuromatrix uses many other sources, too. For example, if someone has back pain and a doctor tells you your x-ray shows “wear and tear” or “degeneration” in your spine, they have received a clear message of danger related to your body that is likely to make their pain worse. Indeed, people with back pain who get an MRI actually reduce their chances of recovery. On the other hand, if that person’s doctor (or physiotherapist!) tells them that the findings on their scan are normal age-related changes (or, better yet, doesn’t order a scan at all), that is a clear safety message. Safety messages can come from anywhere. Exercise can send safety messages to your neuromatrix, and so can a supportive workplace or having a friend around to talk to.ReflectionsSlow progress, hopes for the future and a note of cautionSlow progress“I am still not happy with what has been accepted” — Pat Wall, 1999Danger sharpens pain; safety soothes it. Why, then, do health professionals continue to give people with persistent pain credible evidence of danger? Apart from the obvious — that there is money in telling people their spines are crumbling and their pelvises are out of line, that they have muscle knots that need releasing and cores that need stabilizing — it is because, just as Descartes’ model of pain took almost three centuries to reach its zenith in Western culture, the neuromatrix, still only forty years old, has been accepted only falteringly even in medical circles, and hardly at all in the wider culture.Indeed, in many ways the twentieth century has doubled down on labelled line. Take, for example, the dominance of the orthopaedic understanding of low back pain, which the late Scottish doctor and historian Gordon Waddell called “the dynasty of the disc”. Waddell traces the tenuous association of the lumbar disc with low back pain to a fateful cluster of papers published at the beginning of the century by orthopods searching, like Victorian physicians had done before them, for a pot of gold at the (wrong) end of the labelled line. Even today, routine orthopaedic surgeries like lumbar fusion, knee arthroscopy and shoulder decompression are amongst the most low-value, least evidence-based treatments in healthcare, still performed largely because of inertia and unexamined Cartesianism.Many physiotherapists practice with the same habits. Like Joseph Swann, we might conduct a questionable root-cause analysis up or down a kinetic chain to find an ‘issue in the tissues’, settling on a pronated foot, a slumped posture or a valgus (in-falling) knee. Like Josiah Nott, when a patient has failed a course of ‘corrective’ exercise to ‘fix’ their body we might decide their problem is primarily ‘psycho-social’, a euphemism for in-their-mind. This is understandable, it takes great effort to shift from Cartesianism to the neuromatrix; I have been trying for years and I am still astonished when a new study is published showing, for example, that there are no major physical risk factors for a first episode of neck pain, but multiple psychological ones, like depression, and social ones, like role conflict. Still, it is imperative that medical professionals of all stripes challenge their colleagues who promote themselves as experts but who practice with unreconstructed Cartesianism.Hopes for the Future“While pain sufferers do not have the luxury of denying the reality of their pain, they can and do deny its legitimacy, thereby internalising the stigma so frequently directed at people in pain.” — Daniel GoldbergThe neuromatrix model has the potential to be immensely liberating for patients. For people with everyday predicaments of life like the back or shoulder pain we all get from time to time, there is the reassuring message that pain is not an indicator of damage and they are safe to move. In fact, movement, as opposed to protecting the painful joint, is the way to go in the long run. For people with more profound, widespread and recalcitrant pain, understanding why their pain is the way it is can help with the process of acceptance, and knowing pain is multifactorial can open up new therapeutic options to help calm down a sensitive nervous system.The neuromatrix could also militate against the way Cartesian thinking drives stigmatization of people with chronic pain. Cartesian dualism casts pain as a two-step sequence of events: the body senses pain, then the mind reacts. As recently as the 1980s, words like “hysterical” or “psychogenic” were used to describe people who appeared to be ‘over-reacting’ to their pain. It is this thinking that allows us to sort people into those who are responding appropriately to their pain, and those who are ‘being dramatic’. The saddest effect of this stigma is when patients internalise it, believing that they are not ‘coping’ properly with ‘a bit of back pain’.So patients and health professionals need to know that dualism is bogus: as Pat Wall himself put it, “the separation of sensation from perception was quite artificial… sensory and cognitive mechanisms operate as a whole”. Or, in the words of neuroscientist Fernando Cervero, “emotional, sensory and cognitive elements aren’t organised in a hierarchical way, but in a cooperative way […] interacting to generate the final pain experience”.A note of caution“Nineteenth century physicians drain[ed] pain of any intrinsic meaning altogether, making it little more than a sign or symptom of something else” — Joanna Burke“[The challenge is] to allow a rapprochement between the world of the clinician and the world of the person in pain” — Quinter et. al (2008).The neuromatrix and all its attendant discoveries have revolutionised how medical and health professionals should approach people in pain. It is a rare true paradigm shift. But there is danger in complacency. “Now is not a time for professional hubris or the proclamation of truth by a few”, warn the rheumatologists John Quintner and Milton Cohen. The battle to understand pain is only half won. It is all too easy to be drawn back into the orbit of dualism, not only between the mind and body, but between the clinician and the patient, or the researcher and the sufferer. Centuries-old habits die hard, and we have long made the person-in-pain an object of enquiry. But this can only take us so far; as Quinter and Cohen assert, “the pain of another person is irreducible to its neuronal correlates”. We can only really know pain through dialogue.It is difficult to talk properly about pain. Being in deep pain can be a harrowing, abject, solitary experience. And apart from anything else, often we just don’t have the words: Virginia Woolf, no stranger to pain, lamented that English has a rich vocabulary for love, but a meagre one for pain. The poet Emily Dickinson said that pain “has an element of blank”.But it can be done. Joletta Belton, a blogger with persistent pain, recently tweeted about the two clinicians who had helped her the most. “It wasn’t just their words” she wrote, “it was that they listened first. And understood. Listening matters […] I wasn’t interrupted or lectured, they didn’t try to ‘educate’ me or alter my narrative to suit their own […] I felt what I said was of value. I felt human, of worth. That’s invaluable.”It may seem strange to end a post about science with a note on the importance of listening, but in the context of the neuromatrix it makes perfect sense. Listening to people in pain is what’s needed to undo the damage that has been done, and take the progress that’s been made to the next level.Belton’s experience echoes a vignette reported by Joanna Bourke in The Story of Pain.During a medical consultation in 1730, an embarrassed patient found himself apologising to his physician for boring him with “so tedious a Tale”. The patient’s physician protested: “Your Story is so diverting, that I take abundance of delight in it, and your Ingenious way of telling it, gives me a greater insight into your distemper, than you imagine. Wherefore, let me beg of you to go on, Sir: I am all attention, and shall not interrupt you.”Selected bibliographyJournal ArticlesAllan, D. and Waddell, G. (1989). An historical perspective on low back pain and disability. Acta Orthopaedica Scandinavica, 60(sup234), pp.1–23.Arnaudo, E. (2017). Pain and dualism: Which dualism?. Journal of Evaluation in Clinical Practice, 23(5), pp.1081–1086.Baliki, M. and Apkarian, A. (2015). Nociception, pain, negative moods, and behavior selection. Neuron, 87(3), pp.474–491.Bourke, J. (2014). Pain sensitivity: an unnatural history from 1800 to 1965. Journal of Medical Humanities, 35(3), pp.301–319.Brodal, P. (2017). A neurobiologist’s attempt to understand persistent pain. Scandinavian Journal of Pain, 15(1).Cohen, M., Quintner, J., Buchanan, D., Nielsen, M. and Guy, L. (2011). Stigmatization of Patients with Chronic Pain: The Extinction of Empathy. Pain Medicine, 12(11), pp.1637–1643.Chapman, C., Tuckett, R. and Song, C. (2008). Pain and stress in a systems perspective: reciprocal neural, endocrine, and immune interactions. The Journal of Pain, 9(2), pp.122–145.Eriksen, T., Kerry, R., Mumford, S., Lie, S. and Anjum, R. (2013). At the borders of medical reasoning: aetiological and ontological challenges of medically unexplained symptoms. Philosophy, Ethics, and Humanities in Medicine, 8(1), p.11.Goldberg, D. (2012). Pain without lesion: debate among American neurologists, 1850–1900. 19: Interdisciplinary Studies in the Long Nineteenth Century, 0(15).Goldberg, D. (2017). Pain, objectivity and history: understanding pain stigma. Medical Humanities, 43(4), pp.238–243.Iannetti, G. and Mouraux, A. (2010). From the neuromatrix to the pain matrix (and back). Experimental Brain Research, 205(1), pp.1–12.Kerry, R., Maddocks, M. and Mumford, S. (2008). Philosophy of science and physiotherapy: An insight into practice. Physiotherapy Theory and Practice, 24(6), pp.397–407.Latremoliere, A. and Woolf, C. (2009). Central sensitization: A generator of pain hypersensitivity by central neural plasticity. The Journal of Pain, 10(9), pp.895–926.Melzack, R. (1999). From the gate to the neuromatrix. Pain, 82, pp.S121-S126.Melzack, R. (2005). Evolution of the neuromatrix theory of Pain. The Prithvi Raj Lecture: Presented at the Third World Congress of World Institute of Pain, Barcelona 2004. Pain Practice, 5(2), pp.85–94.Melzack, R. and Katz, J. (2012). Pain. Wiley Interdisciplinary Reviews: Cognitive Science, 4(1), pp.1–15.Mendell, L. (2014). Constructing and deconstructing the gate theory of pain. Pain, 155(2), pp.210–216.Moayedi, M. and Davis, K. (2013). Theories of pain: from specificity to gate control. Journal of Neurophysiology, 109(1), pp.5–12.Moseley, G. and Butler, D. (2015). Fifteen years of explaining pain: the past, present, and future. The Journal of Pain, 16(9), pp.807–813.Moseley, G. (2007). Reconceptualising pain according to modern pain science. Physical Therapy Reviews, 12(3), pp.169–178.Neilson, S. (2015). Pain as metaphor: metaphor and medicine. Medical Humanities, 42(1), pp.3–10.O’Sullivan, P., Caneiro, J., O’Keeffe, M. and O’Sullivan, K. (2016). Unraveling the complexity of low back pain. Journal of Orthopaedic & Sports Physical Therapy, 46(11), pp.932–937.Perl, E. (2007). Ideas about pain, a historical view. Nature Reviews Neuroscience, 8(1), pp.71–80.Quintner, J., Cohen, M., Buchanan, D., Katz, J. and Williamson, O. (2008). Pain Medicine and Its Models: Helping or Hindering?. Pain Medicine, 9(7), pp.824–834.Thacker, M. and Moseley, G. (2012). First-person neuroscience and the understanding of pain. The Medical Journal of Australia, 196(6), pp.410–411.Wiech, K. (2016). Deconstructing the sensation of pain: The influence of cognitive processes on pain perception. Science, 354(6312), pp.584–587.Woolf, C. (2007). Central sensitization. Anesthesiology, 106(4), pp.864–867.BooksCervero, F. (2014). Understanding pain. Boston: Mit Press.Butler, D. and Moseley, G. (2015). Explain pain. Adelaide: Noigroup Publications.Bourke, J. (2014). The story of pain. Oxford: Oxford Univ. Press.Moseley, G. and Butler, D. (2017). Explain pain supercharged. Adelaide: Noigroup Publications.Blog postsPain is weird by Paul IngrahamPain really is in the mind, but not in the way you think by Lorimer MoseleyCentral sensitization in chronic pain by Paul IngrahamMy own chronic pain story by Paul IngrahamEasing musculoskeletal pain Information leafletTell me your story by Joletta BeltonPodcasts and lecturesThe Pain Revolution by Lorimer MoseleyPain: past, present and future with Mick ThackerUnderstanding Pain in 2025 by Mick Thacker Subscribe at tomjesson.substack.com

Today, a discussion of ethics, epidemiology, and COVID-19 with Daniel Goldberg and Ashley Holub.Daniel S. Goldberg is trained as an attorney, a historian of medicine, and a public health ethicist.  His current research agenda in law, policy, and bioethics focuses on: the social determinants of health, public health policy and chronic illness, health inequities, and stigma. In addition, he maintains an active research program in the history of medicine, and focuses primarily on two topics in 19th century America: the history of medical imaging (especially X-rays) and the history of pain without lesion.Dr. Ashley Holub recently graduated with a PhD in epidemiology and has worked in emergency medicine, pediatrics and mental health. She currently a fellow in medical devices and real world analytics and has an interest in scientific communication. 

Fintech companies such as Bridgement can do what no bank can – give you a yes or no answer in 90 minutes, and then deposit cash in your account. CEO Daniel Goldberg explains how this works.

• On this episode of Paradox Podcast: The Business of Video Games, Shams and Daniel discuss the Subscription Services in the industry. Listen in to their musing on the present situation and some future predictions! Discuss this episode on our forums: https://pdxint.at/2PpwHoW • Chapters:What we've been up to – 0:15Topic of the Day: Subscription Services – 5:45Answering your Questions - 34:17• The Paradox Podcast is a podcast about the business of video games, brought to you by Paradox Interactive. Daniel Goldberg (Marketing & Communications) and Shams Jorjani (Business Development and Acquisitions) tries to shed a light on a part of the industry which is seldomly spoken of.•  Spotify: https://pdxint.at/2HFshtu•  Soundcloud: http://pdxint.at/2EYDl15•  iTunes: http://pdxint.at/2BnBWBo•  Player.fm: http://pdxint.at/2EWTCnl•  Poddtoppen: http://pdxint.at/2CiqXGw•  Acast: http://pdxint.at/2ExBD9lSupport the show (http://paradoxplaza.com)

This week we follow Peter Strauss into the Forbidden Zone to rescue three Earth women...

Late payments can make it very difficult for an SME to grow and sometimes just survive - Daniel Goldberg, CEO of Bridgement. www.moneyweb.co.za

Moneyweb Radio — Late payments can make it very difficult for an SME to grow and sometimes just survive - Daniel Goldberg, CEO of Bridgement.

We talk. We drink. We movie. About Old School: After discovering his girlfriend (Juliette Lewis) has been participating in group sex, attorney Mitch (Luke Wilson) feels his world come undone. He moves into a new place, which happens to be near a college campus, and tries to get his life back together. Two of his best friends, Frank (Will Ferrell) and Beanie (Vince Vaughn), start hanging out at Mitch's house, eventually turning the place into a wild party pad, much to the ire of the college's dean, Gordon "Cheese" Pritchard (Jeremy Piven). Release date: February 13, 2003 (USA) Director: Todd Phillips Screenplay: Todd Phillips, Scot Armstrong Story by: Todd Phillips, Scot Armstrong, Court Crandall Producers: Todd Phillips, Daniel Goldberg, Joe Medjuck Get at us: Email: TalkingDuringMoviesPodcast@gmail.com Instagram: @TalkingDuringMovies About Trey: Friend, neighbor, beer buddy and all around good guy ... About your host: I talk, I drink, I movie and I love life. Special thanks to our sponsors: Dive Bar and Lounge - 1703 Guadalupe Austin, TX Color Blind Design - the tactical 6 pack beer holder

Larry and Chris continue their conversation with Daniel Goldberg of Citizen Gold. They discuss more about the creative process and how much social media and crowdfunding affect the work. Enjoy!

Larry and Chris sit down and talk shop with Daniel Goldberg, front man of Citizen Gold. They discuss music, music making and Electric Soul. Enjoy!

As you can probably imagine, ethics in any subject can get very complicated. In this episode, Professor Daniel Goldberg tells us how public health ethics is different from healthcare ethics. What makes a policy or intervention ethically optimal? What evidence exists on structural violence and institutional racism? How powerful are narratives in shaping public health policy? Are science and scientific journals inherently biased? How does the history of Thanksgiving relate to the ethics of understanding Native American health? Buckle down, prepare your brains, and tune in for an ethics ride! Transcript available on website. Hosts: @klattalyst and @sujanee. Guest: Professor Daniel Goldberg. Music: Cordele Glass. Producer: Klattalyst Ltd

• On this episode of The Business of Video Games we finally get the "new" CEO of Paradox Interactive, Ebba Ljugerud, to talk about the first 13 months of being the CEO, as well as the future going forward.Discuss this episode on our forums: https://pdxint.at/2PpwHoW • Chapters:0:47 - Start2:14 - What have we been playing?8:29 - First 13 Months of the CEO• The Paradox Podcast is a podcast about the business of video games, brought to you by Paradox Interactive. Daniel Goldberg (Marketing & Communications) and Shams Jorjani (Business Development and Acquisitions) tries to shed a light on a part of the industry which is seldomly spoken of.•  Spotify: https://pdxint.at/2HFshtu•  Soundcloud: http://pdxint.at/2EYDl15•  iTunes: http://pdxint.at/2BnBWBo•  Player.fm: http://pdxint.at/2EWTCnl•  Poddtoppen: http://pdxint.at/2CiqXGw•  Acast: http://pdxint.at/2ExBD9lSupport the show (http://paradoxplaza.com)

• On this episode of The Business of Video Games we answer questions that you have posed over the course of the show.Discuss this episode on our forums: https://pdxint.at/2PpwHoW • Chapters:0:16 - Start1:29 - Nintendo Switch Lite7:20 - Q&A Start- - 7:38 - How Do You Feel About The Store Revenue Cut?- - 15:37 - What Projects Do You Do Research On?- - 22:04 - How Do You Manage Expectations?• The Paradox Podcast is a podcast about the business of video games, brought to you by Paradox Interactive. Daniel Goldberg (Marketing & Communications) and Shams Jorjani (Business Development and Acquisitions) tries to shed a light on a part of the industry which is seldomly spoken of.•  Spotify: https://pdxint.at/2HFshtu•  Soundcloud: http://pdxint.at/2EYDl15•  iTunes: http://pdxint.at/2BnBWBo•  Player.fm: http://pdxint.at/2EWTCnl•  Poddtoppen: http://pdxint.at/2CiqXGw•  Acast: http://pdxint.at/2ExBD9l#ParadoxInteractive #Podcast #QnASupport the show

• On this episode of The Business of Video Games we discuss how licensing works and why Paradox is doing more licensing than ever before.Discuss this episode on our forums: https://pdxint.at/2PpwHoW • Chapters:0:16 - Start3:20 - What Have We Been Playing?10:10 - Licensing• The Paradox Podcast is a podcast about the business of video games, brought to you by Paradox Interactive. Daniel Goldberg (Marketing & Communications) and Shams Jorjani (Business Development and Acquisitions) tries to shed a light on a part of the industry which is seldomly spoken of.•  Spotify: https://pdxint.at/2HFshtu•  Soundcloud: http://pdxint.at/2EYDl15•  iTunes: http://pdxint.at/2BnBWBo•  Player.fm: http://pdxint.at/2EWTCnl•  Poddtoppen: http://pdxint.at/2CiqXGw•  Acast: http://pdxint.at/2ExBD9l#ParadoxInteractive #PodcastSupport the show (http://paradoxplaza.com)

Researchers at Guardicore Labs have been tracking an unusual cryptominer that seems to be based in China and is targeting Windows MS-SQL and phpMyAdmin servers. Some elements of the exploit make use of sophisticated components previously associated with nation-state actors. Ophir Harpaz and Daniel Goldberg are members of the Guardicore Labs team, and they join us to explain their findings. The research can be found here -  https://www.guardicore.com/2019/05/nansh0u-campaign-hackers-arsenal-grows-stronger/ The CyberWire's Research Saturday is presented by Juniper Networks. Thanks to our sponsor Enveil, closing the last gap in data security.  

Researchers at Guardicore Labs have been tracking an unusual cryptominer that seems to be based in China and is targeting Windows MS-SQL and phpMyAdmin servers. Some elements of the exploit make use of sophisticated components previously associated with nation-state actors. Ophir Harpaz and Daniel Goldberg are members of the Guardicore Labs team, and they join us to explain their findings. The research can be found here -  https://www.guardicore.com/2019/05/nansh0u-campaign-hackers-arsenal-grows-stronger/

• On this episode of The Business of Video Games we invite Johan Bolin, VP of Sales at Paradox Interactive, to talk about how E3 matter to a midsized publisher like Paradox. We also briefly talk about Linux.Discuss this episode on our forums: https://pdxint.at/2PpwHoW • Chapters:0:16 - Episode Start1:17 - What Have We Been Playing?8:17 - Linux Support11:32 - E3 2019• The Paradox Podcast is a podcast about the business of video games, brought to you by Paradox Interactive. Daniel Goldberg (Marketing & Communications) and Shams Jorjani (Business Development and Acquisitions) tries to shed a light on a part of the industry which is seldomly spoken of.•  Spotify: https://pdxint.at/2HFshtu•  Soundcloud: http://pdxint.at/2EYDl15•  iTunes: http://pdxint.at/2BnBWBo•  Player.fm: http://pdxint.at/2EWTCnl•  Poddtoppen: http://pdxint.at/2CiqXGw•  Acast: http://pdxint.at/2ExBD9l#ParadoxInteractive #Podcast #E32019Support the show (http://paradoxplaza.com)

• On this episode of The Business of Video Games we invite Johan Andersson, Game Director of Imperator: Rome, to discuss the release of the game. • Chapters:0:15 - Episode Start4:10 - What Have We Been Playing?6:24 - Imperator: Release• The Paradox Podcast is a podcast about the business of video games, brought to you by Paradox Interactive. Daniel Goldberg (Marketing & Communications) and Shams Jorjani (Business Development and Acquisitions) tries to shed a light on a part of the industry which is seldomly spoken of.•  Spotify: https://pdxint.at/2HFshtu•  Soundcloud: http://pdxint.at/2EYDl15•  iTunes: http://pdxint.at/2BnBWBo•  Player.fm: http://pdxint.at/2EWTCnl•  Poddtoppen: http://pdxint.at/2CiqXGw•  Acast: http://pdxint.at/2ExBD9l#ParadoxInteractive #Podcast #ImperatorRomeSupport the show (http://paradoxplaza.com)

Discuss this episode on our forums: https://pdxint.at/2PpwHoW -On this episode of The Business of Video Games Daniel and Shams discuss the recent announcement that Epic Games is buying Psyonix, developer of the popular rocket powered car soccer game Rocket League, and their views on Epic's place in the games distribution space.The Paradox Podcast is a podcast about the business of video games, brought to you by Paradox Interactive. Daniel Goldberg (Marketing & Communications) and Shams Jorjani (Business Development and Acquisitions) tries to shed a light on a part of the industry which is seldomly spoken of. Spotify: https://pdxint.at/2HFshtu Soundcloud: http://pdxint.at/2EYDl15 iTunes: http://pdxint.at/2BnBWBo Player.fm: http://pdxint.at/2EWTCnl Poddtoppen: http://pdxint.at/2CiqXGw Acast: http://pdxint.at/2ExBD9lSupport the show (http://paradoxplaza.com)

Discuss this episode on our forums: https://pdxint.at/2PpwHoW -On this episode of The Business of Video Games Daniel and Shams talk about the recent announcements of Vampire: The Masquerade - Bloodlines 2 and that Paradox is working on a brand new strategy game with John and Brenda Romero.The Paradox Podcast is a podcast about the business of video games, brought to you by Paradox Interactive. Daniel Goldberg (Marketing & Communications) and Shams Jorjani (Business Development and Acquisitions) tries to shed a light on a part of the industry which is seldomly spoken of. Spotify: https://pdxint.at/2HFshtu Soundcloud: http://pdxint.at/2EYDl15 iTunes: http://pdxint.at/2BnBWBo Player.fm: http://pdxint.at/2EWTCnl Poddtoppen: http://pdxint.at/2CiqXGw Acast: http://pdxint.at/2ExBD9lSupport the show

In this week's podcast, I had the honor of interviewing Daniel Goldberg, Founder and CEO of Gold Medical Marketing. Daniel Goldberg is widely regarded as a pioneer in Medical Marketing and Public Relations and was an integral part of the transition to Direct to Patient Marketing. Daniel’s unique knowledge of the business of healthcare and patient behaviors allow him to create marketing and public relations campaigns that reach specifically targeted audiences that maximize ROI. His ability to identify markets for potential patients allows GMM’s clients to penetrate new audiences and increase patient volume exponentially. Daniel has also lectured both nationally and internationally on the topic of Medical Marketing at some of the most esteemed medical conferences. Daniel founded Gold Medical Marketing in 2012 after serving as the Director of Marketing and Business Development in a private orthopedic / spine practice and ASC. In the process, GMM has grown to be one of the most successful medical marketing firms and represents medical practices across the country. In this interview with CEO and founder, Daniel Goldberg, we focused on web design, brand awareness initiatives, and transactional marketing efforts for the Orthopeadic, Spine or Neurosurgery Practice. We covered: How Inbound Marketing, Web design, and traditional marketing work for orthopedic brands. Current trends or wellness practices with digital marketing in 2019. Why you should create a Quarterly marketing budget for your health center rather than an annual budget. The top 3 things that a wellness center should be doing online to see a return from their SEM efforts. The top strategy that should be followed, but often marketing teams get wrong. Learn more about how to use Digital Marketing for your Healthcare center. I had a couple of great takeaways from this health care marketing interview and I'm sure that you will as well for your own medical practice. First and foremost, it is ever important to make sure your team understands the goals of the marketing programs that you are running. Are your campaigns geared towards one time transactions and getting somebody in the door the first time they search for a specialty? Are they built around branding and brand recognition? Once this is clearly defined, you can have a greater understanding how each campaign actually affects your customer acquisition cost and patient growth. The next takeaway is to take the steps towards better understanding your patient journey. It's not just what happens online, but also their experience within your office. For example, if a prospect sees language online that grows enough confidence in your expertise to give your practice a call, is the front desk knowledgeable about the services that you offer? Can they answer simple questions about the process, the physician, and generally show they place the patient first? Are you making a good first impression with your website, with your social media, with that first phone call? And then lastly, and I think that this is the most important, is thinking about your marketing budget, not as an annual budget, but rather on a quarterly basis. If a campaign is working well for bringing clients in the door and yields a positive ROI from digital marketing for your practice, you do your practice a disservice if the budget for that campaign can't be scaled over time. Conversely, if you are testing a new marketing campaign with A/B testing and optimization, you can't decide after a week that the campaign is a failure. Work the systems, work the processes, and, if after 90 days you still aren't seeing a return, find another avenue to reallocate and test your health center marketing budget. Rather than thinking about your marketing budget as an annual budget, we recommend putting it into three-month increments and doing a quarterly assessment of how your campaigns have either allowed you to reach your marketing goals or where they leave room for improvement. Please be sure to subscribe to the Social Speak Podcast for more interviews with experts in digital marketing for health and wellness businesses. To learn more about Gold Medical Marketing visit: GoldMedicalMarketing.com    

Discuss this episode on our forums: https://pdxint.at/2PpwHoW -On this episode of The Business of Video Games we've invited Wendy Young, Senior Producer at Paradox Development Studio, to talk about her storied history in the games industry, from Barbie games for Gameboy Advance to the first Grand Strategy Game on consoles.The Paradox Podcast is a podcast about the business of video games, brought to you by Paradox Interactive. Daniel Goldberg (Marketing & Communications) and Shams Jorjani (Business Development and Acquisitions) tries to shed a light on a part of the industry which is seldomly spoken of. Spotify: https://pdxint.at/2HFshtu Soundcloud: http://pdxint.at/2EYDl15 iTunes: http://pdxint.at/2BnBWBo Player.fm: http://pdxint.at/2EWTCnl Poddtoppen: http://pdxint.at/2CiqXGw Acast: http://pdxint.at/2ExBD9lSupport the show

Discuss this episode on our forums: https://pdxint.at/2PpwHoW -On this episode we've brought in Rod Humble, studio head of the newly announced Paradox Tectonic studio, to talk about his experiences over the last 30 years in the games industry.The Paradox Podcast is a podcast about the business of video games, brought to you by Paradox Interactive. Daniel Goldberg (Marketing & Communications) and Shams Jorjani (Business Development and Acquisitions) tries to shed a light on a part of the industry which is seldomly spoken of. Spotify: https://pdxint.at/2HFshtu Soundcloud: http://pdxint.at/2EYDl15 iTunes: http://pdxint.at/2BnBWBo Player.fm: http://pdxint.at/2EWTCnl Poddtoppen: http://pdxint.at/2CiqXGw Acast: http://pdxint.at/2ExBD9lSupport the show (http://paradoxplaza.com)

Discuss this episode on our forums: https://pdxint.at/2PpwHoWIn this episode we've brought Jordan Weissman and Mitch Gitelman into the studio to talk about how these industry veterans got their starts and how they came to start Harebrained Schemes, developers of Shadowrun Returns and BattleTech.The Paradox Podcast is a podcast about the business of video games, brought to you by Paradox Interactive. Daniel Goldberg (Marketing & Communications) and Shams Jorjani (Business Development and Acquisitions) tries to shed a light on a part of the industry which is seldomly spoken of. Spotify: https://pdxint.at/2HFshtu Soundcloud: http://pdxint.at/2EYDl15 iTunes: http://pdxint.at/2BnBWBo Player.fm: http://pdxint.at/2EWTCnl Poddtoppen: http://pdxint.at/2CiqXGw Acast: http://pdxint.at/2ExBD9lSupport the show (http://paradoxplaza.com)

Discuss this episode on our forums: https://pdxint.at/2PpwHoWIn this episode Daniel and Shams discuss the recent string of exclusives moving from Steam to the Epic Games Store.The Paradox Podcast is a podcast about the business of video games, brought to you by Paradox Interactive. Daniel Goldberg (Marketing & Communications) and Shams Jorjani (Business Development and Acquisitions) tries to shed a light on a part of the industry which is seldomly spoken of. Spotify: https://pdxint.at/2HFshtu Soundcloud: http://pdxint.at/2EYDl15 iTunes: http://pdxint.at/2BnBWBo Player.fm: http://pdxint.at/2EWTCnl Poddtoppen: http://pdxint.at/2CiqXGw Acast: http://pdxint.at/2ExBD9lSupport the show (http://paradoxplaza.com)

Discuss this episode on our forums: https://pdxint.at/2PpwHoWIn this episode Blondie, Streaming Director at Paradox Interactive, hot off The Grandest LAN talk about streaming at Paradox and what this Grandest LAN is all about.The Paradox Podcast is a podcast about the business of video games, brought to you by Paradox Interactive. Daniel Goldberg (Marketing & Communications) and Shams Jorjani (Business Development and Acquisitions) tries to shed a light on a part of the industry which is seldomly spoken of. Soundcloud: http://pdxint.at/2EYDl15 iTunes: http://pdxint.at/2BnBWBo Player.fm: http://pdxint.at/2EWTCnl Poddtoppen: http://pdxint.at/2CiqXGw Acast: http://pdxint.at/2ExBD9l Paradox on YouTube: --------------------------------- ParadoxInteractive - http://youtube.com/ParadoxInteractive Trailers, Feature Breakdowns, Dev Diaries, and more. ParadoxExtra - http://youtube.com/ParadoxExtra Gameplay of our video games, convention coverage, and other fun things from Paradox! Paradox Grand Strategy - http://youtube.com/ParadoxGrandStrategy Gameplay of our Grand Strategy Games. CK2, EU4, HOI4, Stellaris, and more?Support the show (http://paradoxplaza.com)

Discuss this episode on our forums: https://pdxint.at/2PpwHoWIn this episode Paula Thelin, Event Manager at Paradox Interactive talks about what it takes to go to events with a games publisher, and the massive amounts of work it takes to create PDXCON.The Paradox Podcast is a podcast about the business of video games, brought to you by Paradox Interactive. Daniel Goldberg (Marketing & Communications) and Shams Jorjani (Business Development and Acquisitions) tries to shed a light on a part of the industry which is seldomly spoken of. Soundcloud: http://pdxint.at/2EYDl15 iTunes: http://pdxint.at/2BnBWBo Player.fm: http://pdxint.at/2EWTCnl Poddtoppen: http://pdxint.at/2CiqXGw Acast: http://pdxint.at/2ExBD9l Paradox on YouTube: --------------------------------- ParadoxInteractive - http://youtube.com/ParadoxInteractive Trailers, Feature Breakdowns, Dev Diaries, and more. ParadoxExtra - http://youtube.com/ParadoxExtra Gameplay of our video games, convention coverage, and other fun things from Paradox! Paradox Grand Strategy - http://youtube.com/ParadoxGrandStrategy Gameplay of our Grand Strategy Games. CK2, EU4, HOI4, Stellaris, and more?Support the show (http://paradoxplaza.com)

Discuss this episode on our forums: https://pdxint.at/2PpwHoWSusie McBeth, Senior Community Manager at Paradox Interactive, is invited onto the podcast to talk about what a community manager does and the challenges of the position. Social Media is only 10%.The Paradox Podcast is a podcast about the business of video games, brought to you by Paradox Interactive. Daniel Goldberg (Marketing & Communications) and Shams Jorjani (Business Development and Acquisitions) tries to shed a light on a part of the industry which is seldomly spoken of. Soundcloud: http://pdxint.at/2EYDl15 iTunes: http://pdxint.at/2BnBWBo Player.fm: http://pdxint.at/2EWTCnl Poddtoppen: http://pdxint.at/2CiqXGw Acast: http://pdxint.at/2ExBD9l Paradox on YouTube: --------------------------------- ParadoxInteractive - http://youtube.com/ParadoxInteractive Trailers, Feature Breakdowns, Dev Diaries, and more. ParadoxExtra - http://youtube.com/ParadoxExtra Gameplay of our video games, convention coverage, and other fun things from Paradox! Paradox Grand Strategy - http://youtube.com/ParadoxGrandStrategy Gameplay of our Grand Strategy Games. CK2, EU4, HOI4, Stellaris, and more?Support the show (http://paradoxplaza.com)

Recently, we announced and released Cities: Skylines for Nintendo Switch. In this episode of the Paradox Podcast we invite Jakob Munthe to discuss this announcement, release, and the Nintendo Direct in which we announced the port. The Paradox Podcast is a podcast about the business of video games, brought to you by Paradox Interactive. Daniel Goldberg (Marketing & Communications) and Shams Jorjani (Business Development and Acquisitions) tries to shed a light on a part of the industry which is seldomly spoken of. Soundcloud: http://pdxint.at/2EYDl15 iTunes: http://pdxint.at/2BnBWBo Player.fm: http://pdxint.at/2EWTCnl Poddtoppen: http://pdxint.at/2CiqXGw Acast: http://pdxint.at/2ExBD9l Paradox on YouTube: --------------------------------- ParadoxInteractive - http://youtube.com/ParadoxInteractive Trailers, Feature Breakdowns, Dev Diaries, and more. ParadoxExtra - http://youtube.com/ParadoxExtra Gameplay of our video games, convention coverage, and other fun things from Paradox! Paradox Grand Strategy - http://youtube.com/ParadoxGrandStrategy Gameplay of our Grand Strategy Games. CK2, EU4, HOI4, Stellaris, and more?Support the show (http://paradoxplaza.com)

How secure are your servers? The best way to be sure that your systems aren't being compromised is to do it yourself. In this episode Daniel Goldberg explains how you can use his project Infection Monkey to run a scan of your infrastructure to find and fix the vulnerabilities that can be taken advantage of. He also discusses his reasons for building it in Python, how it compares to other security scanners, and how you can get involved to keep making it better.

Recorded at Gamescom, this episode has a wide range of topics, including the announcement of Stellaris: Console Edition, the announcement of BattleTech: Flashpoint, trade shows, demographics, and more. The Paradox Podcast is a podcast about the business of video games, brought to you by Paradox Interactive. Daniel Goldberg (Marketing & Communications) and Shams Jorjani (Business Development and Acquisitions) tries to shed a light on a part of the industry which is seldomly spoken of. Soundcloud: http://pdxint.at/2EYDl15 iTunes: http://pdxint.at/2BnBWBo Player.fm: http://pdxint.at/2EWTCnl Poddtoppen: http://pdxint.at/2CiqXGw Acast: http://pdxint.at/2ExBD9l Paradox on YouTube: --------------------------------- ParadoxInteractive - http://youtube.com/ParadoxInteractive Trailers, Feature Breakdowns, Dev Diaries, and more. ParadoxExtra - http://youtube.com/ParadoxExtra Gameplay of our video games, convention coverage, and other fun things from Paradox! Paradox Grand Strategy - http://youtube.com/ParadoxGrandStrategy Gameplay of our Grand Strategy Games. CK2, EU4, HOI4, Stellaris, and more?Support the show (http://paradoxplaza.com)

In this episode of the Paradox Podcast Shams and Daniel discuss the recent acquisition of Harebrained Schemes and what this means for both companies. Also, acquisitions in general. The Paradox Podcast is a podcast about the business of video games, brought to you by Paradox Interactive. Daniel Goldberg (Marketing & Communications) and Shams Jorjani (Business Development & Acquisitions) tries to shed a light on a part of the industry which is seldom spoken of. Soundcloud: http://pdxint.at/2EYDl15 iTunes: http://pdxint.at/2BnBWBo Player.fm: http://pdxint.at/2EWTCnl Poddtoppen: http://pdxint.at/2CiqXGw Acast: http://pdxint.at/2ExBD9l Paradox on YouTube: --------------------------------- ParadoxInteractive - http://youtube.com/ParadoxInteractive Trailers, Feature Breakdowns, Dev Diaries, and more. ParadoxExtra - http://youtube.com/ParadoxExtra Gameplay of our video games, convention coverage, and other fun things from Paradox! Paradox Grand Strategy - http://youtube.com/ParadoxGrandStrategy Gameplay of our Grand Strategy Games. CK2, EU4, HOI4, Stellaris, and more?Support the show (http://paradoxplaza.com)

Now on Spotify: https://pdxint.at/2HFshtu In this episode of the Paradox Podcast, Shams and Daniel discuss PDXCON 2018, and it's worth to Paradox as a company, at PDXCON 2018. The Paradox Podcast is a podcast about the business of video games, brought to you by Paradox Interactive. Daniel Goldberg (Marketing & Communications) and Shams Jorjani (Business Development & Acquisitions) tries to shed a light on a part of the industry which is seldom spoken of. Soundcloud: http://pdxint.at/2EYDl15 iTunes: http://pdxint.at/2BnBWBo Player.fm: http://pdxint.at/2EWTCnl Poddtoppen: http://pdxint.at/2CiqXGw Acast: http://pdxint.at/2ExBD9l Paradox on YouTube: --------------------------------- ParadoxInteractive - http://youtube.com/ParadoxInteractive Trailers, Feature Breakdowns, Dev Diaries, and more. ParadoxExtra - http://youtube.com/ParadoxExtra Gameplay of our video games, convention coverage, and other fun things from Paradox! Paradox Grand Strategy - http://youtube.com/ParadoxGrandStrategy Gameplay of our Grand Strategy Games. CK2, EU4, HOI4, Stellaris, and more?Support the show (http://paradoxplaza.com)

In this episode of the Paradox Podcast, Shams and Daniel discuss the release of BattleTech and the subsequent politically/ideologically-charged initial review bombing. Also, can you make a convention that's profitable? The Paradox Podcast is a podcast about the business of video games, brought to you by Paradox Interactive. Daniel Goldberg (Marketing & Communications) and Shams Jorjani (Business Development and Acquisitions) tries to shed a light on a part of the industry which is seldomly spoken of.Support the show (http://paradoxplaza.com)

Now on Spotify: https://pdxint.at/2HFshtu In this episode of the Paradox Podcast, Shams and Daniel discuss accessibility and difficulty in video games. Also there's a breakdown of what went down at GDC. The Paradox Podcast is a podcast about the business of video games, brought to you by Paradox Interactive. Daniel Goldberg (Marketing & Communications) and Shams Jorjani (Business Development & Acquisitions) tries to shed a light on a part of the industry which is seldom spoken of. Soundcloud: http://pdxint.at/2EYDl15 iTunes: http://pdxint.at/2BnBWBo Player.fm: http://pdxint.at/2EWTCnl Poddtoppen: http://pdxint.at/2CiqXGw Acast: http://pdxint.at/2ExBD9l Paradox on YouTube: --------------------------------- ParadoxInteractive - http://youtube.com/ParadoxInteractive Trailers, Feature Breakdowns, Dev Diaries, and more. ParadoxExtra - http://youtube.com/ParadoxExtra Gameplay of our video games, convention coverage, and other fun things from Paradox! Paradox Grand Strategy - http://youtube.com/ParadoxGrandStrategy Gameplay of our Grand Strategy Games. CK2, EU4, HOI4, Stellaris, and more?Support the show (http://paradoxplaza.com)

A podcast about the business of video games from Paradox Interactive. This week - Daniel Goldberg and Shams Jorjani defend the Paradox business model and reveal their dream crossover games. Also - Daniel puts his job on the line to make a point about disruption.Support the show (http://paradoxplaza.com)

A podcast about the business of video games from Paradox Interactive. This week - Daniel Goldberg and Shams Jorjani talk about the cost of making video games. Why is marketing so expensive, what exactly does R&D mean and why haven´t retail game prices changed in the last 25 years?Support the show (http://paradoxplaza.com)

A podcast about the business of video games from Paradox Interactive. This week - Daniel Goldberg and Shams Jorjani discuss future business models and explain why loot boxes are here to stay, like them or not.Support the show

A podcast about the business of video games from Paradox Interactive. This week - Daniel Goldberg and Shams Jorjani discuss the Paradox business model, Electronic Arts, Visceral Games and the so-called death of single player video games.Support the show

A podcast about the business of video games from Paradox Interactive. This week - Daniel Goldberg and Shams Jorjani discuss Steam, the IGN/Humble Bundle acquisition and explain why publishers are so obsessed with building their own distribution platforms.Support the show (http://paradoxplaza.com)

It's time for episode 73! We're talking about Avatar: The Last Airbender season three, including the evolution of the themes of seasons one and two, two of the comics, and the question of cultural appropriation. To get right to the Avatar talk, skip to 00:19:00. What Missy's Been Up To: Reading:Delicious in Dungeon v. 1 by Ryoku Kui The State of Play, edited by Daniel Goldberg and Linus Larsson Watching:Neo Yokio What Merri's Been Up To: Watching: Neo Yokio Bojack Horseman Some Links You Might Find Interesting: Maybe Playerunknown's Battlegrounds Is The Game Of The Decade?! by Tim Rogers Avatar: the Last Airbender - The Delicacy of Character sapphicreynas' tweet Nationalism For Children: How 'Avatar: The Last Airbender' Explores Violence And National Identity by suraj lakshminarasimhan Use and Abuse of Power in Avatar: The Last Airbender by John Goodman A Guide To Cultural Appropriation Vs. Appreciation by Hota Katebi Avatar: The Last Airbender: Bending Boundaries between Appreciation, Appropriation, and Adaptation by Alex Custodio Our Website | Twitter | Facebook | Tumblr | Patreon | Merch

A podcast about the business of video games from Paradox Interactive. This week - Daniel Goldberg and Shams Jorjani reveal Shams´ biggest professional failures, discuss the SNES Classic and reveal what makes a successful games pitch.Support the show (http://paradoxplaza.com)

Vi pratar med Daniel Goldberg om hur man bäst når och skapar effektiva relationer med journalister, värdet av embargo och pressreleaser, vilka journalistknep man bör akta sig för, hur man hanterar och undviker negativ PR, sensationella brakförluster och mycket mer. Relevanta Länkar: @danielg0ldberg Paradox: paradoxplaza.com Stellaris: paradoxplaza.com/stellaris Di Digital: digital.di.se/skribent/daniel-goldberg/ Digitalpodden: digital.di.se/kategori/podd Svenska Hackare: svenskahackare.se Minecraft boken: minecraftboken.se

It’s Christmas! Our favorite time of the year. We hope you’re enjoying your holidays and are surrounded by friends and family. We want to wish you all a very Merry Christmas! This is a slow week in the news of course but we still have some news for you. Obama bans oil & gas drilling in the Arctic & Atlantic, Trumps Border Adjustment Tax, More pipelines shot down and more! Have a question? Click here to ask. Show Notes & Links: Obama Bans Oil & Gas Drilling in the Arctic & Atlantic What Effect Will Trump’s “Border Adjustment Tax” Have? Enviro’s Launch Lawsuit Against Justin Trudeau Approved Pipeline Russia Signs 23 Energy Agreements with Japan Brazilian Firm, Odebrecht, to Pay a Record $3.5B in Petrobras Bribery Scandal Captain Jake “Red Stripe” Frederick Family Donation Page Weekly Rig Count As of 12/16/2016 – The American Rig count is +13 for the week at a total of 637 active rigs. Bulwark Has A Winner! Daniel Goldberg, Assistant Professor at Texas A&M University (Gig ‘Em!), You are the winner this week of Bulwark Long Sleeve FR Two Tone Base Layer! Congrats! Please, send us pictures when they arrive! CLICK HERE TO ENTER FOR YOUR CHANCE TO WIN! Get Mark’s Monthly Events Email Get Automatically Notified About Oil & Gas Events Once a Month Connect with Us Jake Corley | Facebook | LinkedIn | Email Mark LaCour | Facebook | Twitter | LinkedIn | Email | modalpoint.com

 Your Hosts This Episode Anna Ferri | Amanda Wanner | Matthew Murray We discuss online reading vs book reading (“I just want to read the wiki article”), whether pop science is formulaic, if we read non-fiction to learn explicit facts or provoke thought generally, the impact of blog writing/reading on technology books, our audiobook preferences, anti-narratives (handbooks), edutainment, “There is some fiction in my non-fiction!,” lying by omission, hate reads, and more… Technology (Non-Fiction) We Read (or kinda): Recommended What is Code? by Paul Ford, long-form article from Bloomberg Magazine  The Making of Crash Bandicoot by Andy Gavin (The series of blog posts Matthew read; for the deep nerds out there)  The Shallows: What the Internet Is Doing to Our Brains by Nicholas Carr  Extra Lives: Why Video Games Matter by Tom Bissell  Kitten Clone: Inside Alcatel-Lucen by Douglas Coupland (for a unique experience of technology reading)  The Thrilling Adventures of Lovelace and Babbage: The (Mostly) True Story of the First Computer by Sydney Padua  Other books read Dataclysm: Who We Are (When We Think No One's Looking) by Christian Rudder  The State of Play: Creators and Critics on Video Game Culture edited by Daniel Goldberg and Linus Larsson  Free: The Future of a Radical Price by Chris Anderson  The Naked Future: What Happens in a World That Anticipates Your Every Move? by Patrick Tucker  A few more “books” we mentioned(or that Meghan wanted us to mention since she couldn’t be there) The Urban Biking Handbook: The DIY Guide to Building, Rebuilding, Tinkering with, and Repairing Your Bicycle for City Living by Charles Haine  Steve Jobs by Walter Isaacson  The Victorian Internet by Tom Standage  Paper Knowledge: Toward a Media History of Documents by Lisa Gitelman  How It Began: A Time-Traveler’s Guide to the Universe by Chris Impey (example of odd “padding” in non-fiction, but the science stuff is coooool)  BiblioTech: Why Libraries Matter More Than Ever in the Age of Google by John Palfrey  What Technology Wants by Kevin Kelly  Other/Links 7 Things You Should Read About Technology’s Role in Our Future Hatoful Boyfriend - The pigeon dating game Why so few violent video games? by Gregory Avery-Weir (short, funny, recommended)  The World Future Society - produces The Futurist magazine for which Patrick Tucker is an editor… That's Revolting!: Queer Strategies for Resisting Assimilation edited by Mattilda Bernstein Sycamore (an example of a book where the author really invites you to debate and disagree with the arguments in their work)  Check out our Pinterest board of all the Technology (non-fiction) books people in our club read (or tried to read).

This weeks guest is Daniel Goldberg, an active trader and partner at Futex – a proprietary trading firm located in London, UK. Dan has been involved with financial markets since 1995 (straight out of college), and got his start as a book-runner on the exchange floor. He later became a pit trader, and was also there for the transition to electronic markets. These days, Dan plays a major role in training new traders to the firm, and predominantly focusing on two markets; Bunds and Euro Stoxx. Some of the topics we covered during our discussion; how Dan seeks out trading opportunities and uses tools such as the price ladder and market profile. And how macro events effect have a significant impact on his trade decisions. I also ask Dan a bunch of questions centered around prop trading, and he has some really interesting points to share on the topic of risk. So there’s plenty to learn from Dan, enjoy! Note: This interview was recorded 3rd February 2015

I veckans avsnitt gästas vi av författaren och journalisten Daniel Goldberg, som är aktuell med essäsamlingen The State of Play. Förutom en spännande diskussion om spelkritik dukar vi upp med några av höstens största titlar: Halo 5, Rise of the Tomb Raider, StarCraft II: Legacy of the Void och de första intrycken av Fallout 4. […]

Öppna din inventory för här kommer ett P3 Spel-skepp lastat med loot! Realistiska rustningar, längden på en testikeldolk, hur mycket ost det finns i Skyrim och panelens mest episka loot-ögonblick avhandlas i veckans P3 Spel. Veckans panel består av Susanne Möller, Victor Leijonhufvud och Jonas “Sp4zie” Ring som alla njutit av legendariska skatter i spelens värld. Vi snackar rättvis lootfördelning, hoarder-tendenser och prylmetaspelet i League of Legends. Microsofts miljardaffär med Mojang analyseras på djupet tillsammans med författarna Daniel Goldberg och Linus Larsson. Vad betyder Minecraft-försäljningen egentligen för spelarna? I programmet delas det ut betyg till Destiny, Jimmy Håkansson bjuder på en krönika och vi får äntligen en riktigt väderrapport!   Missa inte P3 Spels lootspecial med Angelica Norgren på lördag, 18.03 i P3.

I takt med att vården för våra djur blir allt mer avancerad så har kostnaderna för veterinärvården skjutit i höjden och premierna för djurförsäkringar har följt efter. Men vem är det som i slutändan får betala när ett enkelt bandage på ett hundben kan kosta flera hundra kronor? Sedan ett par år tillbaka har fokus från den organiserade brottsligheten gått från att råna värdetransporter till att blåsa vanliga småsparare på deras bankkonton. Om detta har Daniel Goldberg och Linus Larsson skrivit en bok som kommer ut inom kort och de gästar studion. Ett alternativt sätt till att ha egen lägenhet eller bo i ett stort hus på egen hand är att dela på matkostnader och äta med andra i den gemensamma matsalen. Att bo kollektivt och tillsammans ordna filmvisningar, städdagar och förskola blir enligt experter trendigt igen och vi tittar närmare på denna boendeform. Plånbokens expert på privatekonomi Annika Creutzer svarar på lyssnarnas frågor.

I P3 Spel på söndag beger vi oss till spelmässan Gamex där nyfikna noobs och skillade proffs trängs för att träffa spelutvecklare, prova de senaste spelen och handla gaming-prylar. Panelen är givetvis på plats! Susanne Möller, Johan Hallstan och Victor Leijonhufvud har provspelat Nintendos kommande storsatsning Wii U som utlovar både partyspel och zombieslakt. Victor har byggt hus i Sim City och Johan har spanat in rysk postapokalyps i Metro Last Light. Vi gästas av Daniel Berlin som är speldesigner på Ubisoft Massive och arbetar med flerspelarläget i Far Cry 3, och han berättar om vikten av samarbete och vad som gör en riktigt bra multiplayer. Dessutom så snackar vi om hur peppade fans kan förändra och påverka ett spel med Linus Larsson och Daniel Goldberg som har skrivit boken Minecraft: block, pixlar och att göra sig en hacka. Med ett helt gäng grymma lyssnare på plats på mässan bjuder vi också på både spelquiz och musiktävling! Kan publiken spöa panelen? Vad ser Josef Fares fram emot med Wii U? Hur går det för Samson Wiklund när han ska göra sitt Signerat Samson inför publik? Svaren får du i P3 Spel med Angelica Norgren, 18.03, söndag i P3. Veckans recensioner och bilder från Gamex hittar ni här nedan: Lyssna på programmet så får ni hela recensionerna och svaren på varför spelen fått de betyg de har. HALO 4 (XBOX 360) Victor: 8 Little Big Planet Karting (PS 3) Victor: 5 Johan: 5 Assasin´s Creed III (PC PS3 XBOX 360) Victor: 6 Johan: 7

Conficker, Stuxnet och Flame, trojaner och bootnets, cyberattacker och web-war - ett nytt språk har växt fram i den digitala värld som flera författare vill ge oss inblick i. De kommer på löpande band nu, böckerna som varnar för attacker på internet, som beskriver redan gjorda attacker på nätet och som varnar för krig på nätet. Mark Bowden, författare till boken Viruset. Det första digitala världskriget, beskriver cyberrymden som den arena där kampen mellan ont och gott nu utspelar sig. De onda heter sånt som Conficker, Stuxnet och Flame, virus och trojaner som enligt experter kan hota såväl infrastruktur och stora företag som alla datoranvändares privata liv. De goda är ofta unga män med de unika kunskaper som krävs för att ta upp kampen. Hur ser egentligen hoten på nätet ut och hur rädda ska vi vara? Hans Blix, välkänd expert på massförstörelsevapen och Daniel Goldberg, IT-journalist och en av författarna till Svenska Hackare har läst Mark Bowdens bok och vi hör också en intervju med denna amerikanska författare som också skrivit Black Hawk Down. - Det pågår redan ett krig out there, säger Bowden. I Nya Vågens första sänding för säsongen passar vi på att titta tillbaka på sommaren som gått och spanar lite framåt. Skådespelaren Maja Runeberg, kulturjournalisten Marianne Söderberg och krönikören Ronny Olovsson fiskar i floden av kulturhändelser, skeenden, debatter och utspel. Det handlar bland annat om upplevelsen av artister som verkligen bryr sig om sin publik och om kulturfientlighet. Programledare Kerstin Wixe i Luleå

I år beräknas 18 miljarder appar laddas ner till smarta telefoner världen över. Försäljningen av appar, det vill säga program till mobiltelefoner och läsplattor, beräknas i år uppgå till omkring 100 miljarder kronor. Det pratas om det svenska app-undret, när datanördar blir miljonärer över en natt när en app plötsligt toppar försäljningslistorna. Men vilka är vinnarna och vilka är förlorarna? Vilka är riskerna med den explosionsartade utvecklingen? Medverkade: Anna Caracolias, civilingenjör och vd för mobilutvecklingsbolaget Adimo och Daniel Goldberg, nyhetschef på tidningen Computer Sweden. Programledare: Catarina Friskman.

A conversation between Lisa B. Arbisser, MD, and Daniel Goldberg, MD. Despite more than 200 years of research and debate, the mechanism of accommodation remains a mystery. But new research has revealed clues that may solve this mystery and change the future of surgical presbyopia correction. In this interview, Dr. Daniel Goldberg discusses new findings and shares his consolidated theory of accommodation that may help pave a new course for correcting presbyopia. (April 2011)