Podcasts about Hydrocodone

Increased prescription of opioid medications like oxycodone and hydrocodone has led to widespread misuse of both prescription and non-prescription opioids. But did you know that opioid misuse can significantly impact the endocrine system? The Endocrine Society recently published a scientific statement titled, “Exogenous Opioids and the Human Endocrine System: An Endocrine Society Scientific Statement.” The statement reviews data on the use and misuse of opioids and discusses recent research on the endocrine-related implications of opioid use. Host Aaron Lohr talks to one of the statement’s authors, Niki Karavitaki, MD, PhD, a professor from the Institute of Metabolism and Systems Research at the University of Birmingham in the United Kingdom. Show notes are available at https://www.endocrine.org/podcast/enp98-opioids-and-the-endocrine-system — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

Even though opioids are highly addictive, they continue to be prescribed because they're thought of as the best option for pain management. However, that's not always the case. Dr. Cecile Feldman explains new research that shows how over-the-counter medication is more effective in some cases – and how this revelation is changing prescribing practices in dentistry. Learn More: https://radiohealthjournal.org/the-hydrocodone-hyperbole-the-best-drug-for-pain-isnt-always-an-opioid Learn more about your ad choices. Visit megaphone.fm/adchoices

Many people have heard of the cases we are about to talk about, but there's a couple of important pieces of information that people often get wrong when they talk about them. The first is the belief that a horrific murder of a child under CPS oversight with a detailed history is an anomaly, that's sadly not the case. Now, many people recognize that the amount of people who tried to help the poor boys we are discussing today are more than you could comfortably fit in the room we're sitting in, as well as the fact that dozens upon dozens of calls were made to the police and to various social services to try to save them. And yes, that does not sound real, but as nightmarish as it sounds, it did happen. This happens more often than you think, this channel is proof of that, and one of the worst parts of doing this is we can only cover the victims that are more than a small blurb in the newspaper. Yes, that's right. Most murders, even those involving children, end up being nothing more than a small obituary, or a paragraph on a news website.  The second thing people often get wrong with this case, is that despite the catastrophic negligence of the Los Angeles County Department of Children and Families, the average person believes the spokespeople from LA County who claimed that they would fix every problem in their system and that a case like this would never happen again here. But sadly, it did happen again. It happened at least two more times that we know of. Inside a county that should have known better. A county that openly told us that it knew better. We will talk about those two other times later in the video. But first, let's dive into the cases that opened our eyes to the systemic issues inside of the departments put in place to protect children. These are the stories of Gabriel Fernandez, Anthony Avalos, and Noah Cuatro. Support Our Patreon: https://www.patreon.com/themiserymachine PayPal: https://www.paypal.me/themiserymachine Join Our Facebook Group: https://t.co/DeSZIIMgXs?amp=1 Instagram: miserymachinepodcast Twitter: misery_podcast Discord: https://discord.gg/kCCzjZM #themiserymachine #podcast #truecrime Source Material: https://en.wikipedia.org/wiki/Murder_of_Gabriel_Fernandez https://en.wikipedia.org/wiki/Hydrocodone/paracetamol https://www.youtube.com/watch?v=o70BRxUgKns https://www.youtube.com/watch?v=UlVZlF_4EpY https://abc7.com/gabriel-fernandez-stefanie-rodriguez-patricia-clement-kevin-bom/3573298/ https://en.wikipedia.org/wiki/Capital_punishment_in_California https://www.waze.com/live-map/directions/us/ca/palmdale/the-gabriel-fernandez-memorial-site?to=place.ChIJ5wzKCjBYwoARwmCuA6Z3LzY https://www.youtube.com/watch?v=hICu5STaSbQ https://www.youtube.com/watch?v=-T7VXlB4qUI https://abc7.com/gabriel-fernandez-palmdale-boy-torture-abuse-isauro-aguirre/2568674/ https://time.com/5790549/gabriel-fernandez-netflix-documentary/ https://www.findagrave.com/memorial/207902976/gabriel_daniel-fernandez https://abc7.com/noah-cuatro-dcfs-palmdale-child-dies-abuse/6371338/ https://www.findagrave.com/memorial/201492933/noah-cuatro https://www.latimes.com/california/story/2021-08-19/how-dcfs-failures-led-up-to-noah-cuatro-child-abuse-death  https://theavtimes.com/2022/09/30/judge-denies-expedited-trial-date-for-siblings-of-slain-palmdale-boy/ https://childwelfaremonitor.org/2021/09/14/when-ideology-can-kill-the-death-of-noah-cuatro/ https://abc7.com/noah-cuatro-dcfs-palmdale-child-dies-abuse/6565429/ https://bithiahsfamilyservices.org/ https://www.findagrave.com/memorial/190824058/anthony-nolan-avalos https://www.latimes.com/california/story/2019-09-03/anthony-avalos-timeline https://www.mercurynews.com/2023/04/26/mom-boyfriend-get-life-sentences-in-10-year-old-boys-death/amp/ https://geniuscelebs.com/anthony-avalos-father-victor-avalos-siblings/ https://journalism.berkeley.edu/projects/before-his-death-10-year-old-anthony-avalos-came-out-as-gay-official-says-2/#:~:text=In%20an%20interview%2C%20DCFS%20Director,access%20to%20the%20bathroom%2C%20forced https://www.latimes.com/california/story/2019-09-03/anthony-avalos-timeline https://www.latimes.com/california/story/2019-09-03/anthony-avalos-death-gabriel-fernandez-dcfs-workers?fbclid=IwAR1Czwdqjg7PTjBPm14X2bVWnNejFfpzXAaW9ifumjSnWeeZQg79kNsL-gA https://www.sportskeeda.com/pop-culture/what-happened-anthony-avalos-california-mom-former-boyfriend-found-guilty-10-year-old-s-2018-murder https://people.com/crime/anthony-avalos-allegedly-forced-wrestle-brother-mom-watched/ https://people.com/crime/california-boy-who-came-out-gay-allegedly-tortured/ https://heavy.com/news/2018/06/heather-barron-kareem-leiva/amp/ https://www.nbcnews.com/news/us-news/mother-sentenced-murder-torture-10-year-old-son-rcna81387 https://www.latimes.com/local/lanow/la-me-boy-death-gay-20180626-story.html https://www.lamag.com/citythinkblog/the-short-unhappy-life-of-anthony-avalos/ https://lawandcrime.com/crime/i-hope-she-gets-beat-up-in-jail-mom-and-boyfriend-wont-ever-get-out-of-prison-after-unimaginable-torture-murder-of-10-year-old-anthony-avalos/amp https://www.youtube.com/watch?v=1ddmUSPKEnI&ab_channel=FOX11LosAngeles https://www.youtube.com/watch?v=GXe9y9kMVQQ&ab_channel=FOX11LosAngeles https://www.youtube.com/watch?v=VxJSXw0XLMI&ab_channel=ABC7 https://abc7chicago.com/anthony-avalos-death-mom-heather-barron-parents/12791230/ https://www.turnto23.com/news/local-news/da-to-seek-death-penalty-for-mother-boyfriend-charged-in-murder-of-10-year-old-anthony-avalos https://abc7.com/anthony-avalos-half-siblings-testify-trial-los-angeles/12759887/ https://journalism.berkeley.edu/projects/before-his-death-10-year-old-anthony-avalos-came-out-as-gay-official-says-2/#:~:text=In%20an%20interview%2C%20DCFS%20Director,access%20to%20the%20bathroom%2C%20forced https://www.nbcnews.com/news/us-news/mother-sentenced-murder-torture-10-year-old-son-rcna81387 https://docs.google.com/document/d/1cfxDnNxmMM8ZW5qWu_0vsOE_F0jnWS7b/edit# https://www.newsweek.com/heather-barron-convicted-torture-murder-son-anthony-avalos-1786302 https://goodmantherapy.com/meet-the-therapists/shane-bulkley-acsw/ https://www.facebook.com/profile.php?id=100008885851887 https://www.facebook.com/mariabarronx11 https://www.facebook.com/TheAnthonyAvalosTree/ https://www.facebook.com/watch/?v=10156828441354614 https://www.facebook.com/groups/227844851161847/ https://www.facebook.com/gia.greaux https://www.facebook.com/childrenscenterav https://www.facebook.com/david.barron.334491 https://www.facebook.com/maria.barron.73307634 https://www.facebook.com/That1girlCJ https://abc7.com/noah-cuatros-parents-sentenced-to-potential-life-terms-for-4-year-old-palmdale-boys-death/14745636/ https://ciris.mt.cdcr.ca.gov/search https://www.oxygen.com/crime-news/gabriel-fernandez-case-david-martinez-dies-of-covid-19 https://www.dignitymemorial.com/obituaries/san-fernando-ca/michael-lemos-carranza-6137111 https://www.avpress.com/news/cuatro-s-family-settles-with-la-county/article_791ed29c-c1af-11ef-8155-83a7d95c58af.html https://www.oxygen.com/crime-news/barbara-dixon-probation-abuse-gabriel-fernandez-anthony-avalos

If you or someone you know is struggling with opioid addiction, then this episode of Sick Health has a lot of hopeful and practical tips for you. In about 25 minutes, you'll learn everything you need to know about the latest opioid crisis statistics, addiction treatments, and affordable remedies that could save your life or the life of someone you love (right from the shelf of your pharmacy). Join us as we delve into the pressing issue of opioid addiction and explore a range of OTC medications that offer amazing benefits. Dr. Kevin Ban guides us through these different treatments while making a key distinction between heroin and fentanyl overdoses. But this discussion is more than just an eye-opening account of the opioid epidemic's evolution. This tipping point for addiction treatment is framed by the success of other well-known OTC applications.Stressing the need for more affordable over-the-counter treatments, Dr. Ban walks us through other health emergencies made treatable with well-known OTC medications for acute allergic reactions and pain management.Give us 25 minutes and we'll give you:- An understanding of the opioid addiction crisis- Insights into revolutionary, life-saving meds that can go in your pocket- Knowledge about using both H1 and H2 blockers for comprehensive allergic reaction management.- Pain management tips and techniquesPut the power of your health back in your hands with this episode filled with actionable advice and insights to help you and your loved ones stay healthy and safe!This episode references Graphs, Data and Materials Developed by the CDC. Use of this material does not constitute endorsement or recommendation by the U.S. Government, Department of Health and Human Services, or Centers for Disease Control and Prevention. These materials are available on the CDC website for no charge:https://www.cdc.gov/overdose-prevention/about/understanding-the-opioid-overdose-epidemic.html https://www.cdc.gov/nchs/nvss/vsrr/drug-overdose-data.htmExplore whether your state has Narcan available by standing order - your healthcare insurance may cover it.Sharing Beauty:  “Her Morning Elegance” by Oren LavieStop Motion Dance Film / Music Videohttps://youtu.be/2_HXUhShhmY?si=K_8HNL2jtzlIu1bKContact email:  team@sickhealthshow.comExecutive Producer: Kevin Ban, MDProduction Director and Producer:  Bat-Sheva GuezEditor: Emily BranhamGraphic designer: Leah VanWhyYouTube SEO: Lighthouse-Digitalmarketing.comSocial media: Rebekah PajakInterns: Nicole Berritto & Niccolo Ban To see the graphs Kevin walks through, watch us on YouTube (and leave your comments!) at https://www.youtube.com/@SickHealthwithKevinBanMD

KSQD 05-16-2024: The super power of the resilient Tardigrade is their fabulous DNA repair ability.< /br> How do I tolerate another knee surgery after getting intestinal adhesions because of previous surgery?< /br> Can I avoid an operation to fix a displaced cataract lens?< /br> A patient with Parkinson's disease and knee problems is warned against speculative and expensive alternative treatment. A man with major swallowing problems needs an endoscopy ASAP -- Dr. Dawn bashes corporation control over conventional medicine. A borderline diabetic asks for diet advice. Cancer prevention policies are up against Insurance payment denial policies. The reasons why colorectal cancer is on the rise in 20 to 50 yr-olds -- colonoscopies are now recommended for younger adults.

This week I talk about the medication shortages across the United States. Drugs used to treat ADHD, chronic pain, and other conditions have been in short supply lately for reasons unexplained. Different groups have blamed the shortage on one anther: the manufacturers blame the DEA, while the DEA blames manufacturers. But as usual, the problem comes down to a design issue.  For more about Assent's issues with the DEA, check out the Reason article, "DEA Shuts Down Factory even as Adderall Shortage Persists." Support the show

Some of today's top storiesa disturbing eyewitness account of a man seen on video walking around with a severed body part from a train crash. It happened last Friday in Wasco. Witnesses tell us, 27-year-old Resendo Tellez is the man seen in this video carrying around a severed leg... and accuse him of biting into it. That body part... belonging to a victim hit and killed by a train at the Wasco Amtrak Station.  Before the incident, Tellez was seen in security footage shared with 17 News... visiting a liquor store. He's the one in the orange shirt. Those who know Tellez say he is homeless, and describe him as ordinary and polite. A construction worker spoke to... tells us he was in the area when he saw Tellez carrying around the body part.Court records Tellez has at least a half dozen prior misdemeanor convictions... mostly for drug or alcohol-related offenses.  Tellez is scheduled for a court appearance Tuesday in Shafter.David Abbasi -- a candidate in this month's election for Kern County Supervisor -- was arrested for calling 9-1-1 too many times. Abbasi told 17 News he was booked into jail Sunday and released yesterday morning.    He said he was "falsely arrested and imprisoned."     Abbasi, who says he has asthma, explained that one of his business neighbors has consistently been smoking indoors, leading to the smoke creeping into his own unit.    He also says he had to go to the hospital for breathing treatment, and out of for fear of an asthma attack, he called 9-1-1 multiple times.Turning to an grim update on Kern County's fentanyl crisis.    Just days after the triumphant debut of his latest music documentary, investigators say local filmmaker Nate Berg died of a fentanyl overdose. Back in January... Berg was found down on the sidewalk in the middle of the night in downtown Bakersfield.     He had been ill with an undiagnosed respiratory illness – and some speculated he had Covid-19.    But yesterday afternoon the Kern County Coroner's Office made official of what some of those close to him had feared.    Berg died of acute Hydrocodone and fentanyl toxicity – an accidental overdose.    He is now one of the more than 900 people in Kern who have died from fentanyl-related overdoses in the past four years.The number of in-custody deaths is on the rise even as the number of incarcerated people continues to decline.    Kern County is among the counties setting an in-custody death record.     17's Mikhala Armstrong has more.

A Survey of Skin Reactions Associated With Acrylic NailCosmetics, with a Focus on Home Kits: Is There a Needfor Regulation? Guenther J, Norman T, Wee CP, Adler BLDermatitis (2023).Combination of Acetaminophen and Ibuprofen is Non-Inferior to Acetaminophen and Hydrocodone for Post-NailProcedure Analgesia: A Randomized Controlled TrialHwang JK, Ricardo JW, Lipner SR Journal of the American Academy of Dermatology (2023)A Breath of Fresh Air: Use of Deep Breathing Technique toMinimize Pain with Nail Injections. Hill RC, Chernoff KA, Lipner SR.Journal of the American Academy of Dermatology. (2023)

While you're eating yourself silly this Thanksgiving-- and loosening your belts-- spare a thought for the underserved billionaires.

Visit: https://nursing.com/140meds to request your free copy of "140 Must Know Meds" Generic Name hydrocodone/acetaminophen Trade Name Vicodin, Lortab, Norco Indication management of moderate to severe pain Action alters the perception and reaction to pain by binding to opiate receptors in the CNS, also suppresses the cough reflex Therapeutic Class opioid Analgesic, allergy, cold and cough remedies, antitussive Pharmacologic Class opioid agonists, nonopioid analgesic combinations Nursing Considerations • use caution with concurrent use of MAOI – avoid use within 14 days of each other • hypotension – monitor hemodynamics and respirations after administering • may increase ICP use caution with head trauma • Narcan (nalaxone) is the antidote for overdose • DO NOT exceed 4g of acetaminophen per day

This week the boyz are getting serious. The Opioid epidemic has claimed the lives of millions of Americans, including a few that The Boyz have known personally. In fact, I'm sure that you have known quite a few people lost to this scourge. It's a sad subject that we are attempting to bring some bit of levity to, so press that button and get educated, and maybe, just maybe, get a couple chucks in while you are at it.

Dr. Don Stader, MD, and Dr. Rachael Duncan, PharmD, sit down to chat with Dr. Heath McAnally, MD, to discuss the nuances between different opioid agents and how to choose between them to match your patient's needs. Tune in as we review the biological pain pathways and how the mu and kappa receptors are involved with different opioid agents and then talk through common opioids including morphine, hydrocodone, oxycodone, codeine, tramadol, fentanyl, and tapentadol. Iowa Healthcare Collaborative presents the Compass Opioid Stewardship Expert Spotlight podcast in partnership with the Centers for Medicare and Medicaid Services. Visit their website for more information on the Compass Opioid Stewardship Program  

This podcast episode will delve into the topic of the four most dangerous opioids: fentanyl, hydrocodone, carfentanil, and tramadol. Fentanyl is a powerful synthetic opioid that is 50-100 times more potent than morphine. It is often added to other drugs, such as heroin, cocaine, and methamphetamine, making it even more dangerous. Overdose deaths related to fentanyl have been on the rise in recent years. Hydrocodone is a semi-synthetic opioid that is commonly prescribed for pain management. It is also highly addictive and can lead to overdose when taken in large quantities or combination with other substances. Carfentanil is a highly potent synthetic opioid that is used as a tranquilizer for large animals. It is 10,000 times more potent than morphine and should not be used by humans. Carfentanil has been responsible for a significant number of opioid overdoses in recent years. Tramadol is a synthetic opioid that is commonly prescribed for pain management. Although it is considered to be less potent than other opioids, it can still lead to addiction and overdose when misused. Join us as we discuss the dangers of these opioids, their effects on the body, and the consequences of misuse. --- Send in a voice message: https://podcasters.spotify.com/pod/show/darkcancerproductions/message Support this podcast: https://podcasters.spotify.com/pod/show/darkcancerproductions/support

Plus, violent crime is down in Dallas and Dak Prescott scheduled to have surgery today.

Let's face it, when it comes to pain management, one of the most painful efforts of the last few years has involved, in one way, shape, form, or fashion: Morphine Milligram Equivalents (MMEs). As we discussed with the PharmD author of the 2022 CDC Opioid Guideline Update , there are no MME factor changes on the horizon, so just when will we have our minds wrapped around the concept?!?   Join the Mark “Pain Guy” Garofoli on the Pain Pod for a dynamic discussion on wrestling (yes, you read that right!), pain management, our healthcare system, and the “street” version of MMEs. Wait, there's a street version of MMEs? Yes, yes there is, so tune in now to the Pain Pod as you'll only utilize the edge of your seat even though ya paid for the whole seat!   Come one, come all, to the Pain Pod!!!   Episode Notes   Pre-2016 MME Charts Review · Nielson S. et. al. A synthesis of oral morphine equivalents (OME) for opioid utilization studies. Pharmacoepidemiology and drug safety 2016; 25: 733–737  2016 CDC Chronic Pain Opioid Guideline MME Chart ·      CDC Chronic Pain Opioid Guidelines: MMWR March 2016. Updated 2017. o   Tramadol: 0.1 o   Codeine: 0.15 o   Tapentadol: 0.4 o   Morphine: 1 o   Hydrocodone: 1 o   Oxycodone: 1.5 o   Oxymorphone: 3 o   Hydromorphone: 4 o   Methadone (Up to: 20mg, 40mg, 60mg, >60mg): 4, 8, 10, 12 o   Transdermal Fentanyl: 7.2 (Divided by the # of Days Applied) o   Transdermal Buprenorphine: 12.6 (Divided by the # of Days Applied) o   Buprenorphine (SL or Buccal): 0.03 (for mcg calculations) or 30 (for mg calculations)   2015 Cat and Dog MME Article · https://burrardvet.com/2015/04/08/pain-control-in-dogs-cats   2016 CDC Chronic Pain Opioid Guideline MME Chart · CDC Chronic Pain Opioid Guidelines: MMWR March 2016. Updated 2017.   2022 CDC Opioid Guideline Revision Resources · https://www.federalregister.gov/documents/2022/02/10/2022-02802/proposed-2022-cdc-clinical-practice-guideline-for-prescribing-opioids   2010 to 2014 MME Relative Risk of Overdose/Death · https://i1.wp.com/face-facts.org/wp-content/uploads/2017/04/Opioid-dose-vs-overdose-risk.jpg   Missouri Marijuana Equivalents (MMEs) · https://north.life/demystifying-missouri-medical-marijuana-equivalency-units-mmes/     Audio Add-in's Let's Get Ready to Rumble (Michael Buffer) · https://www.youtube.com/watch?v=jgopHWACUXs   Cash sound · https://www.youtube.com/watch?v=ZeET7Z1ZGlw   Ron Burgundy “That Escalated Quickly” · https://www.youtube.com/watch?v=FONN-0uoTHI Learn more about your ad choices. Visit megaphone.fm/adchoices

In this first of 2 podcasts episodes, Alison Towerman, RN, MSN, CPNP, and Michael R. DeBaun, MD, MPH, discuss  best practices for the management of painful vaso-occlusive crises (VOCs) in patients with sickle cell disease, review the disease pathophysiology, and provide emergency department and outpatient setting recommendations on nonpharmacologic and pharmacologic management of painful VOCs.  This activity is available for 0.25 ANCC and 0.25 AAPA credits, with 0.25 credits applicable for pharmacology credit for NPs. To receive credit for this program, go to pce.is/sickle.Contributors:Michael R. DeBaun, MD, MPHDirectorVanderbilt-Meharry Center for Excellence in Sickle Cell DiseaseProfessorPediatrics and MedicineVice Chair for Clinical and Translational ResearchDepartment of PediatricsJ.C. Peterson Chair in PediatricsNashville, TennesseeMichael R. DeBaun, MD, MPH: consulting, speaker, and advisory board fees: Forma, GBT, Novartis, and Vertix.Alison Towerman, RN, MSN, CPNPPediatric Nurse PractitionerDepartment of Pediatrics, Division of Hematology/OncologyWashington University School of Medicine in St. LouisSt. Louis, Missouri Ms. Towerman has no relevant financial relationships to disclose.

In this episode, Erik Shaw, DO, FAAPMR, discusses factors that should be reviewed before starting treatment with an opioid, as well as details on patient and provider responsibilities with opioid therapy. Listen as Dr Shaw interviews a patient with chronic pain to demonstrate application of these concepts in clinical practice.Presenter:  Erik Shaw, DO, FAAPMRChairAAPM&R Opioid Task ForceMedical DirectorShepherd Spine and Pain InstituteAtlanta, GeorgiaThis activity is supported by an independent educational grant from the Opioid Analgesic REMS Program Companies. Please seehttps://bit.ly/3mgrfb9for a listing of REMS Program Companies. This activity is intended to be fully compliant with the Opioid Analgesic REMS education requirements issued by the FDA.Provided by Clinical Care Options, LLC, and in partnership with the American Academy of Physical Medicine and Rehabilitation, Practicing Clinicians Exchange, and ProCE.Link to full program:https://bit.ly/3mcDHsi 

In this podcast, Dr. Betty Martini answered a letter by Vicki Young who is addicted to Diet Coke and suffers from Crohn's disease. Vicki is also on chronic therapy with Norco which is a combination of acetaminophen and Hydrocodone. If you would like to read the full letter, please contact Dr. Martini through her website at www.mpwhi.com (770 242 2599) If you would like to find out how to heal from the Diet Coke addiction, contact Dr. Henderson at www.revwinnhendersonmd.com. (828 508 7981)

Season 1 Episode 2: The Enemy Within Oh my god! Gross! Body Horror! Nobody liked Kawalsky Anyway! Talking points: Wait, How do you pronounce Goa'uld? If you do a murder whilst harboring a...Goold (?), should you be arrested? And should someone who trades sides over just seeing a Casio really be on the team? ----more----00:00 Intro 04:35 You got 24 seconds 09:26 Episode Recap 42:25 Were You Comforted 49:10 Yeh Neh and Meh 51:35 Outro

Washington County Sheriff 's Deputies and Investigators executed a search warrant on Chance Lane in the McIntosh community Friday, June 11 after receiving complaints from the community and conducting an investigation into possible drug distribution activity. Deputies located approximately 29 grams of crack cocaine, 35 grams of marijuana, Hydrocodone pills, Roxicodone pills, drug scales, and a handgun. As a result, investigators arrested Gabriel Hill, 29, and Warren Andry, 23, both of McIntosh. Andry is charged with possession of a controlled substance and has since been released on bond. Hill is charged with possession of crack cocaine with intent to distribute,...Article Link

This time on the Couch: Mike, James, and Shée wonder why a gorilla would wear a suit when they read Strange Adventures no. 201! If you were printing comics in the 60s, there was no better way to move units than to put a primate in your book and set him loose on an unsuspecting hero. Also, if you were printing comics in the 60s, hopefully you swiped enough copies of Amazing Fantasy no. 15 to have retired by now. But while you were achieving financial independence, D-lister Animal Man was fighting a 400-pound monster in a fedora, and getting absolutely wrecked in the process! Maybe next time try absorbing the abilities of an animal that can reconstruct its spine after it's been ground into paste! Plus, in another tale, two daring adventurers with the same fashion sense fight their way through a surreal hellscape in order to tip over an old man's tub of Hydrocodone. Enjoy your joint pain, grandpa! That's what you get for doing your squats incorrectly all these years!

When a young podcaster contracts a mysterious illness, his mother must decide how far she will drive to bring him the supplies he needs to stay alive. On Episode 454 of Trick or Treat Radio we discuss the film, Son from Writer/Director Ivan Kavanagh! We also talk about the proper way to get your COVID vaccination, cursed puppet shows, and the hottest place to party, Area 54! So grab your favorite pair of sequined hot pants, try not to spit up too much blood, and strap on for the world's most dangerous podcast! Stuff we talk about: Shudder, Fangoria Chainsaw Awards, Castle Graybeard, Adams Family, Arachnaphobia, MZ vaccination report, eye of the beholder, what does MRI mean?, Ravenshadow’s triumphant appearance on the Movie Massacre podcast, smoking helmet dome, the COVID life cycle, Three’s Company, The Secret of Skinwalker Ranch, Studio 51 or Area 54, Xenomorph, Wes Borland, the MZ infomercial of the week, Teeel, Tom Wilson, cameo, Jim Smith, Barry Horowitz, Superman: Red Son, Speed Racer, Emile Hirsch, Andi Matichak, Bad News Bears, Gods giving birth to children, ballin’ on a budget, Uncrustables and Cigarettes, Resident Evil, Parliament Funkadelic, medium sized Big Show, bad blood fx, annoying kids, opinions, The Canal, Quarantine Titans, free shots, Double D, Kobayashi Maru, primo gange, pot delivery, Rosemary’s Baby, Son of Rosemary, The Autopsy of Jane Doe, puppet shows in Tiny’s basement, MZ eating ants, eclairs covered in ants, choking on the chicken, Brood X, “gypsy mawths”, Gangrel and The Brood, shrunken head, stairway snake, Beetlejuice, John Cicada, ribbed ankle cuffs, Cavity Colors, Hydrocodone, “make me get that happen”, and Creepshow.Support us on Patreon: https://www.patreon.com/trickortreatradioJoin our Discord Community: https://discord.gg/ETE79ZkSend Email/Voicemail: mailto:podcast@trickortreatradio.comVisit our website: http://trickortreatradio.comStart your own podcast: https://www.buzzsprout.com/?referrer_id=386Use our Amazon link: http://amzn.to/2CTdZzKFB Group: http://www.facebook.com/groups/trickortreatradioTwitter: http://twitter.com/TrickTreatRadioFacebook: http://facebook.com/TrickOrTreatRadioYouTube: http://youtube.com/TrickOrTreatRadioInstagram: http://instagram.com/TrickorTreatRadioSupport the show (https://www.patreon.com/trickortreatradio)

This episode is also available as a blog post: https://youarewithinthenorms.com/2020/06/09/the-folson-amicus-brief/ BACKGROUND As far as can be determined as a practicing Pharmacist who is not an attorney the Red Flags of Diversion gained the most traction in the Holiday CVS, L.L.C., d/b/a CVS/Pharmacy Nos. 219 and 5195 cases. However, in that case, the Pharmacies in question were regular chain drug stores but Pronto Pharmacy is a specialty pharmacy that specializes in pain management and compounding. Therefore, they are in different classes. It's like the difference between a general practitioner and a surgeon. True, they are both doctors, but their level of training is not the same and the selection of patients is not the same. A general practitioner might be able to stitch you up after a fall but removing your gall bladder would clearly be beyond his scope of practice. With that in mind consider that Dr. Clement has advanced training in therapeutics, pain management, Dentistry, Forensics, and more than 45 years, experience, and the typical CVS Pharmacist has less than 5 years, experience. The business model for CVS focuses on high-speed production and Pronto Pharmacy is focused on disease state management. And, just like people might travel long distances to seek out a surgeon that has a high level of training and a history of positive outcomes the same would be true of Pronto Pharmacy. You would be hard-pressed to find a CVS Pharmacist that could have the time to investigate chronic pain treatment modalities and how they impact severely compromised patients. However, Dr. Clement has numerous sources of information that the typical Pharmacist would not be aware of. As a Clinical Pharmacist, I have seen some of his vast library of information and was suitably impressed. So, things that might be a “red flag” to the inexperienced Pharmacist are little more than a footnote for us. Many of our patients have been on service for many years so the red flags may have been resolved years or even decades ago. Therefore, the documentation of the same might not be captured by an investigator that does not interview the patient, the Physician, or the Pharmacist. Often, the pertinent information is archived. In the Holliday CVS case one issue was the dispensing of narcotic prescriptions from prescribers with expired or revoked DEA registrations. This did not happen at Pronto Pharmacy. HIGH DOSE OPIOIDS At trial, the expert witness for the DEA, Dr. Donald Sullivan contended that the Oxycodone and Hydrocodone were the highest available dosage form. However, this is misleading in the world of pain management. Many states require that the prescriptions for C-2 narcotics contain a maximal daily dose, and in the Holliday CVS case, the maximum daily dose for Oxycodone was 6 tablets of 30mg which is 180 mg per day. I have seen this dose in several states, and it is considered the top of the Oxycodone range for severe pain. --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app Support this podcast: https://anchor.fm/norman-j-clement/support

A podcast producer takes part in a sleep study that becomes a nightmarish descent into the depths of his mind and a frightening examination of his aversion to chicken salad. On Episode 452 of Trick or Treat Radio we discuss the film Come True from writer/director Anthony Scott Burns! This retro-futuristic nightmare is an examination of the self and of our nightmares. Speaking of nightmares, we find out that Ravenshadow not only has a first bedtime, but a second bedtime! What the everloving hell? There is also plenty of discussion of sandwiches, and the strange effects of melatonin. So grab your favorite frozen sandwich, place it next to your nightstand to thaw, and strap on your sleep study suit and check out the world's most dangerous podcast!Stuff we talk about: Blackout Tapes, The Snyder Cut, Justice League, MZ’s shirtless appearance, Falcon and Winter Soldier, Superman and Lois, Cake, trepidations, Silver Spoons, Fuck Ricky Schroeder, Peepsi, Josssssss Wheedon, Queen of Black Magic, The Devils, Powerblocks, Hydrocodone, Uncrustables, thaw and eat thing, second bedtime, how to make your own PB&J, your grocers freezer, the effects of melatonin, Doomsday Clock in Watchmen, mothersmucker, Fluffernutter, food in a basket, April Fools Day, Axel Braun, Martian Milfhunter, Jocelyn Donahue, Holidays, retro futuristic 80s aesthetic, Tron, sleep studies, short term memory loss, chicken salad, Resident Evil, Silent Hill, H.R. Giger, Eraserhead, PILOTPRIEST, Matt Mahurin, sleep paralysis, The Nightmare, Room 237, Rodney Ascher, Weekend at Bernies, Terminator, Night of the Living Dead, George A. Romero, Electric Youth, Tiffany Helm, Phillip K. Dick, Blade Runner, Total Recall, low key chaos, Contracted, Der Samurai, IFC Midnight, Chinese Checkers, Najarra Townsend, Brea Grant, Journey to the West, Bad Boy Bubby, analog technology, Guillermo del Toro, the Quarantine Titans, Wet Dreams Come True, putting the cauc back in caucus, and Dial D For Dead Air.Support us on Patreon: https://www.patreon.com/trickortreatradioJoin our Discord Community: https://discord.gg/ETE79ZkSend Email/Voicemail: mailto:podcast@trickortreatradio.comVisit our website: http://trickortreatradio.comStart your own podcast: https://www.buzzsprout.com/?referrer_id=386Use our Amazon link: http://amzn.to/2CTdZzKFB Group: http://www.facebook.com/groups/trickortreatradioTwitter: http://twitter.com/TrickTreatRadioFacebook: http://facebook.com/TrickOrTreatRadioYouTube: http://youtube.com/TrickOrTreatRadioInstagram: http://instagram.com/TrickorTreatRadioSupport the show (https://www.patreon.com/trickortreatradio)

Hello everyone ! This week on The Bachelor is traditionally titled “Hometown Dates.” However, since all of the families have to quarantine at the Neapolitan due to COVID, the remaining contestants call this week “Home Visits.”  Some Guy in Austin and I discuss many things this episode, such as: Michelle’s darling parentsThe Gilmore Girl-ness of Bri and her momSerena’s deadpan sister and her fierce wordsAnd facts about Canada, eh? We also hypothesize the sound of bone crunching as Rachael's face crashes into a lush grassy knoll over by the Neapolitan golf course. How did her features remain unscathed? Did she make a deal with the devil?  And were her glassy eyes a product of an emotional reunion with her parents? Or the remnants of Hydrocodone? We clearly have a lot of feelings and a lot of questions about the logistics of this date and genuinely wonder if Rachael is a cyborg.  EPISODE NOTES: Here’s Matt James’ hometown dates recap! And here’s the link to our official Bachelorette Bracket we are playing with my favorite sports podcast, Last Night’s Game. I can’t wait!!! SHOW NOTES: Subscribe to Podcast: iTunes or Android Newsletter Subscription: HERE Follow Me: Facebook and Instagram and Twitter Buy My Books: It’s a Love Story and Why I Hate Green Beans

Hello everyone ! This week on The Bachelor is traditionally titled “Hometown Dates.” However, since all of the families have to quarantine at the Neapolitan due to COVID, the remaining contestants call this week “Home Visits.”  Some Guy in Austin and I discuss many things this episode, such as: Michelle’s darling parentsThe Gilmore Girl-ness of Bri and her momSerena’s deadpan sister and her fierce wordsAnd facts about Canada, eh? We also hypothesize the sound of bone crunching as Rachael's face crashes into a lush grassy knoll over by the Neapolitan golf course. How did her features remain unscathed? Did she make a deal with the devil?  And were her glassy eyes a product of an emotional reunion with her parents? Or the remnants of Hydrocodone? We clearly have a lot of feelings and a lot of questions about the logistics of this date and genuinely wonder if Rachael is a cyborg.  EPISODE NOTES: Here’s Matt James’ hometown dates recap! And here’s the link to our official Bachelorette Bracket we are playing with my favorite sports podcast, Last Night’s Game. I can’t wait!!! SHOW NOTES: Subscribe to Podcast: iTunes or Android Newsletter Subscription: HERE Follow Me: Facebook and Instagram and Twitter Buy My Books: It’s a Love Story and Why I Hate Green Beans

A very modest study that observed 20 patients found out that oxycodone (with APAP) was 1.5 times stronger than Hydrocodone. However, other studies have revealed that both drugs offer the same degree of pain relief.https://recoverypartnernetwork.com/drug/opioid/oxycodone-addiction

The length of time Lortab stays in an individual's system depends on many variables, including age, metabolism, fluid intake, liver and kidney function, dosage, and other medication consumed. The acetaminophen in Lortab has a half-life of 1.15 to 3 hrs in the blood. Hydrocodone has a half-life of about 4 hours. It is detectable in urine tests for up to three days, depending on other factors. It can be detected in a hair test for up to 90 days. https://recoverypartnernetwork.com/drug/opioid/lortab-addiction

Taking hydrocodone could make an individual feel tired and drowsy. However, it can also cause disrupted sleep patterns and insomnia. https://recoverypartnernetwork.com/drug/opioid/hydrocodone-addiction

Hydrocodone is a synthetic opioid derivative of codeine.https://recoverypartnernetwork.com/drug/opioid/hydrocodone-addiction

The dose is usually not more than six tablets per day. Norco® is one tablet every 4 to 6 hours as needed. Anything more is considered too much.https://recoverypartnernetwork.com/drug/opioid/hydrocodone-addiction

Hydrocodone is a very popular, readily available opioid pain medication....really a big deal in the States. Oxycodone, Hydrocodone, the 2 big hitters in the acute and chronic pain arena, most of us will see these in our lifetime- friends, family, Us! Nice to know a bit about these readily available and useful tools for pain management.

Opioids are a class of drugs that act on opioid receptors in the brain. Signals sent to these receptors can block pain and lead to feelings of euphoria. Different types of opioids differ in a few key ways: the form of the drug (i. e. powder, tar, pill, liquid, etc.), how potent they are, how long their effects last and their potential for addiction.Morphine is a naturally occurring substance derived from the opium poppy plant often used to alleviate pain and other physical ailments. The U.S. classifies it in Schedule II, which means the federal government has determined that it has potential for misuse and dependence, but also has accepted medical use and can be prescribed to patients.https://drug-rehab-delray-beach.s3.amazonaws.com/ttc.htmlhttps://ttc-addiction-treatment.business.site/https://batchgeo.com/map/681ecafc169a47b7124bbe82fd1e775fhttps://batchgeo.com/map/7274655833ed942b86e23474567769e6https://goo.gl/maps/T6YAqq72Bhp9mXFHAhttps://goo.gl/maps/GXmvsx2h7iqsKSpq6https://goo.gl/maps/QCc8GLHhLUKUWcSy7https://t.co/RJRtlnt7bx#opioid-rehab-delrayhttps://t.co/A1qCrlVuaM#morphine-addiction-treatmenthttps://t.co/ygNYBpDSnL#substance-abuse-rehabhttps://earth.google.com/web/data=Mj8KPQo7CiExWTdScXFOT2NwLW11Um9BZUtkUjk5c24zc215czNzUHcSFgoUMEE2NzRGRkM2NjE4NTExNTgxMjEIt is classified as a Schedule I substance, which means the federal government has determined that it has no currently accepted medical use. However, heroin (diacetylmorphine) is available medically in some limited circumstances, particularly in Europe and Canada. In the U.S., almost all heroin comes from the unregulated market. Oxycodone and Hydrocodone are semisynthetic opioids derived from the opium poppy plant, are chemically similar to morphine and are used to treat acute and chronic pain.Oxycodone and hydrocodone are Schedule II substances, which means that the federal government has determined that it has accepted medical use is one of the most powerful opiate-based painkillers, used to treat chronic pain patients who have developed a resistance to other less powerful opiates such as morphine or oxycodone.Transformations Treatment Center14000 S Military Trail, Delray Beach, FL 33484FV9H+MC Delray Beach, Floridahttps://www.transformationstreatment.center/delray-beach-fl/drug-rehab/Morphine Detox in South FloridaFind Transformations on Google Maps!More Information:https://transformationstreatment1.blogspot.com/2021/01/morphine-detox-south-florida.htmlVideos:https://youtu.be/0k7LRjS34ichttps://vimeo.com/502269576Support the show (https://www.google.com/maps?cid=9720609399900639450)

View the show notes in Google Docs here: http://bit.ly/3bFS43j Gonorrhea Updates Gonorrhea Treatment and Care. Centers for Disease Control and Prevention Website. https://www.cdc.gov/std/gonorrhea/treatment.htm. Published December 14, 2020. Accessed January 11, 2021. CDC No Longer Recommends Oral Drug for Gonorrhea Treatment. Centers for Disease Control and Prevention. https://www.cdc.gov/nchhstp/newsroom/2012/gctx-guidelines-pressrelease.html. Published August 9, 2012. Accessed January 11, 2021. Recurrent UTI Recurrent Uncomplicated Urinary Tract Infections in Women: AUA/CUA/SUFU Guideline (2019). American Urological Association. https://www.auanet.org/guidelines/recurrent-uti?fbclid=IwAR1TwSTQNHv8PDWLfW7WjsDan46D_9b6Qs1ptJxaXr6YFnDpBeptpW3BY. Published 2019. Accessed January 11, 2021. Combo Ibuprofen and Acetaminophen / Pain Advil® Dual Action. GSK Expert Portal. https://www.gskhealthpartner.com/en-us/pain-relief/brands/advil/products/dual-action/?utmsource=google&utmmedium=cpc&utmterm=ibuprofen+acetaminophen&utmcampaign=GS+-+Unbranded+Advil+DA+-+Alone+-+PH. Accessed January 11, 2021. FDA approves GSK's Advil Dual Action with Acetaminophen for over-the-counter use in the United States. GSK. https://www.gsk.com/en-gb/media/press-releases/fda-approves-gsk-s-advil-dual-action-with-acetaminophen-for-over-the-counter-use-in-the-united-states/. Published March 2, 2020. Accessed January 11, 2021. Tanner T, Aspley S, Munn A, Thomas T. The pharmacokinetic profile of a novel fixed-dose combination tablet of ibuprofen and paracetamol. BMC clinical pharmacology. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906415/. Published July 5, 2010. Accessed January 11, 2021. Searle S, Muse D, Paluch E, et al. Efficacy and Safety of Single and Multiple Doses of a Fixed-dose Combination of Ibuprofen and Acetaminophen in the Treatment of Postsurgical Dental Pain: Results From 2 Phase 3, Randomized, Parallel-group, Double-blind, Placebo-controlled Studies. The Clinical journal of pain. https://pubmed.ncbi.nlm.nih.gov/32271183/. Published July 2020. Accessed January 11, 2021. 1000 mg versus 600/650 mg Acetaminophen for Pain or Fever: A Review of the Clinical Efficacy. National Center for Biotechnology Information. https://www.ncbi.nlm.nih.gov/books/NBK373467/. Published June 17, 2016. Accessed January 11, 2021. Motov S. Is There a Limit to the Analgesic Effect of Pain Medications? Medscape. https://www.medscape.com/viewarticle/574279. Published June 17, 2008. Accessed January 11, 2021. Motov, Sergey. Faculty Forum: A Practical Approach to Pain Management. YouTube. https://www.youtube.com/watch?v=lJSioPsGw3A. The Center for Medical Education. Published December 2, 2020. Accessed January 1, 2021. Wuhrman E, Cooney MF. Acute Pain: Assessment and Treatment. Medscape. https://www.medscape.com/viewarticle/735034_4. Published January 3, 2011. Accessed January 11, 2021. Social Pain Dewall CN, Macdonald G, Webster GD, et al. Acetaminophen reduces social pain: behavioral and neural evidence. Psychological science. https://pubmed.ncbi.nlm.nih.gov/20548058/. Published June 14, 2010. Accessed January 11, 2021. Mischkowski D, Crocker J, Way BM. From painkiller to empathy killer: acetaminophen (paracetamol) reduces empathy for pain. Social cognitive and affective neuroscience. https://pubmed.ncbi.nlm.nih.gov/27217114/. Published May 5, 2016. Accessed January 11, 2021. Other / Recurrent liner notes Center for Medical Education. https://courses.ccme.org/. Accessed January 11, 2021. Roberts M, Roberts JR. The Proceduralist. https://www.theproceduralist.org/. Accessed January 11, 2021. The Procedural Pause by James R. Roberts, MD, & Martha Roberts, ACNP, PNP. Emergency Medicine News. https://journals.lww.com/em-news/blog/theproceduralpause/pages/default.aspx. Accessed January 11, 2021. The Skeptics' Guide to Emergency Medicine. sgem.ccme.org. https://sgem.ccme.org/. Accessed January 11, 2021. Trivia Question: Send answers to 2viewcast@gmail.com Please note that you must answer the 2 part question to win a copy of the EMRA Pain Guide. “What controversial drug was given a black box warning for prolonged QT and torsades in 2012 and now has been declared by WHICH organization to be an effective and safe treatment use for nausea, vomiting, headache and agitation?” Practical Pain Management in Acute Care Setting Handout Sergey Motov, MD @painfreeED • Pain is one of the most common reasons for patients to visit the emergency department and other acute care settings. Due to the extensive number of visits related to pain, clinicians and midlevel providers should be aware of the various options, both pharmacological and nonpharmacological, available to treat patients with acute pain. • As the death toll from the opioid epidemic continues to grow, the use of opioids in the acute care setting as a first-line treatment for analgesia is becoming increasingly controversial and challenging. • There is a growing body of literature that is advocating for more judicious use of opioids and well as their prescribing and for broader use of non-pharmacological and non-opioid pain management strategies. • The channels/enzymes/receptors targeted analgesia (CERTA) concept is based on our improved understanding of the neurobiological aspect of pain with a shift from a symptom-based approach to pain to a mechanistic approach. This targeted analgesic approach allows for a broader utilization of synergistic combinations of nonopioid analgesia and more refined and judicious (rescue) use of opioids. These synergistic combinations result in greater analgesia, fewer side effects, lesser sedation, and shorter LOS. (Motov et al 2016) General Principles: Management of acute pain in the acute care setting should be patient-centered and pain syndrome-specific by using multimodal approach that include non-pharmacological modalities and pharmacological ones that include non-opioid and opioid analgesics. Assessment of acute pain should be based on a need for analgesics to improve functionality, rather than patients-reported pain scores. Brief pain inventory short form BPI-SF is better than NRS/VAS as it assesses quantitative and qualitative impact of pain (Im et al 2020). ED clinicians should engage patients in shared decision-making about overall treatment goals and expectations, the natural trajectory of the specific painful condition, and analgesic options including short-term and long-term benefits and risks of adverse effects. If acute pain lasting beyond the expected duration, complications of acute pain should be ruled out and transition to non-opioid therapy and non-pharmacological therapy should be attempted. Non-Pharmacologic Therapies • Acute care providers should consider applications of heat or cold as well as specific recommendations regarding activity and exercise. • Music therapy is a useful non-pharmacologic therapy for pain reduction in acute care setting (music-assisted relaxation, therapeutic listening/musical requests, musical diversion, song writing, and therapeutic singing (Mandel 2019). • The use of alternative and complementary therapies, such as acupuncture, guided imagery, cognitive-behavioral therapy, and hypnosis have not been systemically evaluated for use in the Acute care setting including ED. (Dillan 2005, Hoffman 2007) • In general, their application may be limited for a single visit, but continued investigation in their safety and efficacy is strongly encouraged. • Practitioners may also consider utilization of osteopathic manipulation techniques, such as high velocity, low amplitude techniques, muscle energy techniques, and soft tissue techniques for patients presenting to the acute care setting with pain syndromes of skeletal, arthroidal, or myofascial origins. (Eisenhart 2003) Opioids • Acute Care providers are uniquely positioned to combat the opioid epidemic by thoughtful prescribing of parenteral and oral opioids in inpatient setting and upon discharge, and through their engagement with opioid addicted patients in acute care setting. • Acute Care providers should make every effort to utilize non-pharmacological modalities and non-opioid analgesics to alleviate pain, and to use opioid analgesics only when the benefits of opioids are felt to outweigh the risks. (not routinely) • When opioids are used for acute pain, clinicians should combine them with non-pharmacologic and non-opioid pharmacologic therapy: Yoga, exercise, cognitive behavioral therapy, complementary/alternative medical therapies (acupuncture); NSAID's, Acetaminophen, Topical Analgesics, Nerve blocks, etc. • When considering opioids for acute pain, Acute Care providers should involve patients in shared decision-making about analgesic options and opioid alternatives, risks and benefits of opioid therapies, and rational expectations about the pain trajectory and management approach. • When considering opioids for acute pain, acute care providers should counsel patients regarding serious adverse effects such as sedation and respiratory depression, pruritus and constipation, and rapid development of tolerance and hyperalgesia. • When considering administration of opioids for acute pain, acute care providers should make every effort to accesses respective state's Prescription Drug Monitoring Program (PDMP). The data obtained from PDMP's to be used to identify excessive dosages and dangerous combinations, identify and counsel patients with opioid use disorder, offer referral for addiction treatment. • PDMPs can provide clinicians with comprehensive prescribing information to improve clinical decisions around opioids. However, PDMPs vary tremendously in their accessibility and usability in the ED, which limits their effectiveness at the point of care. Problems are complicated by varying state-to-state requirements for data availability and accessibility. Several potential solutions to improving the utility of PDMPs in EDs include integrating PDMPs with electronic health records, implementing unsolicited reporting and prescription context, improving PDMP accessibility, data analytics, and expanding the scope of PDMPs. (Eldert et al, 2018) • Parenteral opioids when used in titratable fashion are effective, safe, and easily reversible analgesics that quickly relieve pain. • Acute care clinicians should consider administering these analgesics for patients in acute pain where the likelihood of analgesic benefit is judged to exceed the likelihood of harm. • Parenteral opioids must be titrated regardless of their initial dosing regimens (weight-based or fixed) until pain is optimized to acceptable level (functionality status) or side effects become intolerable. • When parenteral opioids are used, patients should be engaged in shared-decision making regarding the route of administration, as repetitive attempts of IV cannulation and intramuscular injections are associated with pain. In addition, intramuscular injections are associated with unpredictable absorption rates, and complications such as muscle necrosis, soft tissue infection and the need for dose escalation. (Von Kemp 1989, Yamanaka 1985, Johnson 1976) • Morphine sulfate provides better balance of analgesic efficacy and safety among all parenteral opioids. a. Dosing regimens and routes: b. IV: 0.05-0.1mg/kg to start, titrate q 10-20 min c. IV: 4-6 mg fixed, titrate q 10-20 min d. SQ: 4-6 mg fixed, titrate q 20 min e. Nebulized: 0.2 mg/kg or 10-20 mg fixed, repeat q 15-20 min f. PCA: prone to dosing errors g. IM: should be avoided (pain, muscle fibrosis, necrosis, increase in dosing requirements) • Hydromorphone should be avoided as a first-line opioid due to significant euphoria and severe respiratory depression requiring naloxone reversal. Due to higher lipophilicity, Hydromorphone use is associated with higher rates of euphoria and subsequent development of addiction. Should hydromorphone be administered in higher than equi-analgesic morphine milligram equivalents, close cardiopulmonary monitoring is strongly recommended. Dosing h. IV: 0.2-0.5 mg initial, titrate q10-15 min i. IM: to be avoided (pain, muscle fibrosis, necrosis, increase in dosing requirements) j. PCA: prone to dosing errors (severe CNS and respiratory depression) k. Significantly worse AE profile in comparison to Morphine l. Equianalgesic IV conversion (1 mg HM=8mg of MS) m. Overprescribed in >50% of patients n. Inappropriately large dosing in EM literature: 2 mg IVP o. Abuse potential (severely euphoric due to lipophilicity) • Fentanyl is the most potent opioid, short-acting, requires frequent titration. Dosing: p. IV: 0.25-0.5 μg/kg (WB), titrate q10 min q. IV: 25-50 μg (fixed), titrate q10 min r. Nebulization: 2-4 μg/kg, titrate q20-30 min s. IN: 1-2 μg/kg, titrate q5-10min t. Transbuccal: 100-200μg disolvable tablets u. Transmucosal: 15-20 mcg/kg Lollypops • Opioids in Renal Insufficiency/Renal Failure Patients-requires balance of ORAE with pain control by starting with lower-than-recommended doses and slowly titrate up the dose while extending the dosing interval. (Dean 2004, Wright 2011) • Opioid-induced pruritus is centrally mediated process via μ-opioid receptors as naloxone, nalbuphine reverse it, and can be caused by opioids w/o histamine release (Fentanyl). Use ultra-low-dose naloxone of 0.25 -1 mcg/kg/hr with NNT of 3.5. (Kjellberg 2001) • When intravascular access is unobtainable, acute care clinicians should consider utilization of intranasal (fentanyl), nebulized (fentanyl and morphine), or transmucosal (rapidly dissolvable fentanyl tablets) routes of analgesic administration for patients with acute painful conditions. • Breath actuated nebulizer (BAN): enclosed canister, dual mode: continuous and on-demand, less occupational exposures. a. Fentanyl: 2-4 mcg//kg for children, 4 mcg/kg for adults: titration q 10 min up to three doses via breath-actuated nebulizer (BAN): systemic bioavailability of 50-60% of IV route. (Miner 2007, Furyk 2009, Farahmand 2014) b. Morphine: 10-20 mg g10 min up to 3 doses via breath-actuated nebulizer (BAN)-Systemic bioavailability (concentration) of 30-35% of IV Route. (Fulda 2005, Bounes 2009, Grissa 2015) c. Intranasal Fentanyl: IN via MAD at 1-2 mcg/kg titration q 5 min (use highly concentrated solution of 100mcg/ml for adults and 50 mcg/ml for children)- systemic bioavailability of 90% of IV dosing. (Karisen 2013, Borland 2007, Saunders 2010, Holdgate 2010) d. IN route: shorter time to analgesia, titratable, comparable pain relief to IV route, minimal amount of side effects, similar rates of rescue analgesia, great patients and staff satisfaction. Disadvantages: requires highly concentrated solutions that not readily available in the ED, contraindicated in facial/nasal trauma. Oral Opioids • Oral opioid administration is effective for most patients in the acute care setting, however, there is no appreciable analgesic difference between commonly used opioids (oxycodone, hydrocodone and morphine sulfate immediate release (MSIR). • When oral opioids are used for acute pain, the lowest effective dose and fewest number of tablets needed should be prescribed. In most cases, less than 3 days' worth are necessary, and rarely more than 5 days' worth are needed. • If painful condition outlasts three-day supply, re-evaluation in health-care facility is beneficial. Consider expediting follow-up care if the patient's condition is expected to require more than a three-day supply of opioid analgesics. • Only Immediate release (short-acting) formulary are to be prescribed in the acute care setting and at discharge. • Clinicians should not administer or prescribe long-acting, extended-release, or sustained-release opioid formulations, which include both oral and transdermal (fentanyl) medications in the acute care setting. These formulations are not indicated for acute pain and carry a high risk of overdose, particularly in opioid-naïve patients. • Acute care providers should counsel patients about safe medication storage and disposal, as well as the consequences of failure to do this; potential for abuse and misuse by others (teens and young adults), and potential for overdose and death (children and teens). • Oxycodone is no more effective than other opioids (hydrocodone, MSIR). Oxycodone has highest potential for abuse, misuse and diversion as well as increased risks of overdose, addiction and death. Oxycodone should be avoided as a first-line oral opioid for acute pain. ( Strayer 2016) • If still prescribed, lowest dose (5mg) in combination with acetaminophen (lowest dose of 325 mg) should be considered as it associated with less abuse and diversion (in theory). Potential for acetaminophen overdose exist though with combination. • Hydrocodone is three times more prescribed than oxycodone, but three times less used for non-medical purpose. Combo with APAP (Vicodin)-Use lowest effective dose for hydrocodone and APAP (5/325). (Quinn 1997, Adams 2006) • Immediate release morphine sulfate (MSIR) administration is associated with lesser degree of euphoria and consequently, less abuse potential (Wightman 2012). ED providers should consider prescribing Morphine Sulfate Immediate Release Tablets (MSIR) (Wong 2012, Campos 2014) for acute pain due to: o Similar analgesic efficacy to Oxycodone and Hydrocodone o Less euphoria (less abuse potential) o Less street value (less diversion) o More dysphoria in large doses o Less abuse liability and likeability • Tramadol should not be used in acute care setting and at discharge due to severe risks of adverse effects, drug-drug interactions, and overdose. There is very limited data supporting better analgesic efficacy of tramadol in comparison to placebo, or better analgesia than APAP or Ibuprofen. Tramadol dose not match analgesic efficacy of traditional opioids. (Juurlink 2018, Jasinski 1993, Babalonis 2013) • Side effects are: o Seizures o Hypoglycemia o Hyponatremia o Serotonin syndrome o Abuse and addiction • Codeine and Codeine/APAP is a weak analgesic that provides no better pain relief than placebo. Codeine must not be administered to children due to: o dangers of the polymorphisms of the cytochrome P450 iso-enzyme: o ultra-rapid metabolizers: respiratory depression and death o poor metabolizers: absent or insufficient pain relief • Transmucosal fentanyl (15 and 20 mcg/kg lollypops) has an onset of analgesia in 5 to 15 minutes with a peak effect seen in 15 to 30 minutes (Arthur 2012). • Transbuccal route can be used right at the triage to provide rapid analgesia and as a bridge to intravenous analgesia in acute care setting. (Ashburn 2011). A rapidly dissolving trans-buccal fentanyl (100mcg dose) provides fast pain relief onset (median 10 min), great analgesics efficacy, minimal need for rescue medication and lack of side effects in comparison to oxycodone/acetaminophen tablet (Shear 2010) • Morphine Milligram Equivalent (MME) is a numerical standard against which most opioids can be compared, yielding a comparison of each medication's potency. MME does not give any information of medications efficacy or how well medication works, but it is used to assess comparative potency of other analgesics. • By converting the dose of an opioid to a morphine equivalent dose, a clinician can determine whether a cumulative daily dose of opioids approaches an amount associated with increased risk of overdose and to identify patients who may benefit from closer monitoring, reduction or tapering of opioids, prescribing of naloxone, and other measures to reduce risk of overdose. • Opioid-induced hyperalgesia: o opioid-induced hyperalgesia (OIH) is a rare syndrome of increasing pain, often accompanied by neuroexcitatory effects, in the setting of increasing opioid therapy. o Morphine is by far the most common opiate implicated in OIH. Hydromorphone and oxycodone, members of the same class of opiate as morphine (phenanthrenes), can also cause OIH. Fentanyl, a synthetic opioid in the class of phenylpiperidine, is less likely to precipitate OIH. Existing data suggests that OIH is caused by multiple opioid-induced changes to the central nervous system including: -Activation of N-methyl-D-aspartate (NMDA) receptors -Inhibition of the glutamate transporter system -Increased levels of the pro-nociceptive peptides within the dorsal root ganglia -Activation of descending pain facilitation from the rostral ventromedial medulla -Neuroexcitatory effects provoked by metabolites of morphine and hydromorphone • OIH can be confused with tolerance as in both cases patients report increased pain on opioids. The two conditions can be differentiated based on the patient's response to opioids. In tolerance, the patient's pain will improve with dose escalation. In OIH, pain will worsen with opioid administration. This paradoxical effect is one of the hallmarks of the syndrome. Non-opioid analgesics • Acetaminophen is indicated for management of mild to moderate pain and as a single analgesic and has modest efficacy at most. Addition of Acetaminophen to Ibuprofen does not provide better analgesia for patients with acute low back pain. The greatest limitation to the use of intravenous (IV) versus oral acetaminophen is the nearly 100-fold cost differential, which is likely not justified by any marginal improvement in pain relief. Furthermore, IV APAP provide faster onset of analgesia only after an initial dose. (Yeh 2012, Serinken 2012) • NSAIDs should be administered at their lowest effective analgesic doses both in the ED and upon discharge and should be given for the shortest appropriate treatment course. Caution is strongly advised when NSAIDs are used in patients at risk for renal insufficiency, heart failure, and gastrointestinal hemorrhage, as well as in the elderly. Strong consideration should be given to topical NSAID's in managing as variety of acute and chronic painful Musculo-skeletal syndromes. The analgesic ceiling refers to the dose of a drug beyond which any further dose increase will not result in additional analgesic efficacy. Thus, the analgesics ceiling for ibuprofen is 400 mg per dose (1200 mg/24 h) and for ketorolac is 10 mg per dose (10 mg/24 h). These doses are less than those often prescribed for control of inflammation and fever. When it comes to equipotent doses of different NSAIDs, there is no difference in analgesic efficacy. • Ketamine, at sub-dissociative doses (also known as low-dose ketamine or analgesic dose ketamine) of 0.1 to 0.4 mg/kg, provided effective analgesia as a single agent or as an adjunct to opioids (reducing the need for opioids) in the treatment of acute traumatic and nontraumatic pain in the ED. This effective analgesia, however, must be balanced against high rates of minor adverse side effects (14%–80%), though typically short-lived and not requiring intervention. In addition to IV rout, ketamine can be administered via IN,SQ, and Nebulized route. • Local anesthetics are widely used in the ED for topical, local, regional, intra-articular, and systemic anesthesia and analgesia. Local anesthetics (esters and amides) possess analgesic and anti-hyperalgesic properties by non-competitively blocking neuronal sodium channels. o Topical analgesics containing lidocaine come in patches, ointments, and creams have been used to treat pain from acute sprains, strains, and contusions as well as variety of acute inflammatory and chronic neuropathic conditions, including postherpetic neuralgia (PHN), complex regional pain syndromes (CRPS) and painful diabetic neuropathy (PDN). o UGRA used for patients with lower extremity fractures or dislocations (eg, femoral nerve block, fascia iliaca compartment block) demonstrated significant pain control, decreased need for rescue analgesia, and first-attempt procedural success. In addition, UGRA demonstrated few procedural complications, minimal need for rescue analgesia, and great patient satisfaction. o Analgesic efficacy and safety of IV lidocaine has been evaluated in patients with renal colic and acute lower back pain. Although promising, this therapy will need to be studied in larger populations with underlying cardiac disease before it can be broadly used. o knvlsd • Antidopaminergic and Neuroleptics are frequently used in acute care settings for treatment of migraine headache, chronic abdominal pain, cannabis-induced hyperemesis. • Anti-convulsant (gabapentin and pregabalin) are not recommended for management of acute pain unless pain is of neuropathic origin. Side effects, particularly when combined with opioids (potentiation of euphoria and respiratory depression), titration to effect, and poor patients' compliance are limiting factors to their use. (Peckham 2018) References: Chang HY, Daubresse M, Kruszewski SP, et al. Prevalence and treatment of pain in EDs in the United States, 2000 to 2010. Am J Emerg Med 2014;32(5):421–31. Green SM. There is oligo-evidence for oligoanalgesia. Ann Emerg Med 2012;60: 212–4. Strayer RJ, Motov SM, Nelson LS. Something for pain: Responsible opioid use in emergency medicine. Am J Emerg Med. 2017 Feb;35(2):337-341. Smith RJ, Rhodes K, Paciotti B, Kelly S,et al. Patient Perspectives of Acute Pain Management in the Era of the Opioid Epidemic. Ann Emerg Med. 2015 Sep;66(3):246-252 Meisel ZF, Smith RJ. Engaging patients around the risks of opioid misuse in the emergency department. Pain Manag. 2015 Sep;5(5):323-6. Wightman R, Perrone J. (2017). Opioids. In Strayer R, Motov S, Nelson L (Eds.), Management of Pain and Procedural Sedation in Acute Care. http://painandpsa.org/opioids/ Motov S, Nelson L, Advanced Concepts and Controversies in Emergency Department Pain Management. Anesthesiol Clin. 2016 Jun;34(2):271-85. doi: 10.1016/j.anclin.2016.01.006. Ducharme J. Non-opioid pain medications to consider for emergency department patients. Available at: http://www.acepnow.com/article/non-opioid-painmedications- consider-emergency-department-patients/. 2015. Wightman R, Perrone J, Portelli I, et al. Likeability and Abuse Liability of Commonly Prescribed Opioids. J Med Toxicol. September 2012. doi: 10.1007/s12181-012-0263-x Zacny JP, Lichtor SA. Within-subject comparison of the psychopharmacological profiles of oral oxycodone and oral morphine in non-drug-abusing volunteers. Psychopharmacology (Berl) 2008 Jan;196(1):105–16. Hoppe JA, Nelson LS, Perrone J, Weiner SG, Prescribing Opioids Safely in the Emergency Department (POSED) Study Investigators. Opioid Prescribing in a Cross Section of US Emergency Departments. Ann Emerg Med. 2015;66(3):253–259. Baehren DF, Marco CA, Droz DE, et al. A statewide prescription monitoring program affects emergency department prescribing behaviors. Ann Emerg Med. 2010; 56(1):19–23 Weiner SG, Griggs CA, Mitchell PM, et al. Clinician impression versus prescription drug monitoring program criteria in the assessment of drug-seeking behavior in the emergency department. Ann Emerg Med 2013;62(4):281–9. Greenwood-Ericksen MB, Poon SJ, Nelson LS, Weiner SG, et al. Best Practices for Prescription Drug Monitoring Programs in the Emergency Department Setting: Results of an Expert Panel. Ann Emerg Med. 2016 Jun;67(6):755-764 Patanwala AE, Keim SM, Erstad BL. Intravenous opioids for severe acute pain in the emergency department. Ann Pharmacother 2010;44(11):1800–9. Bijur PE, Kenny MK, Gallagher EJ. Intravenous morphine at 0.1 mg/kg is not effective for controlling severe acute pain in the majority of patients. Ann Emerg Med 2005; 46:362–7. Birnbaum A, Esses D, Bijur PE, et al. Randomized double-blind placebo- controlled trial of two intravenous morphine dosages (0.10 mg/kg and 0.15 mg/kg) in emergency department patients with moderate to severe acute pain. Ann Emerg Med. 2007;49(4):445–53. Patanwala AE, Edwards CJ, Stolz L, et al. Should morphine dosing be weight based for analgesia in the emergency department? J Opioid Manag 2012; 8(1):51–5. Lvovschi V, Auburn F, Bonnet P, et al. Intravenous morphine titration to treat severe pain in the ED. Am J Emerg Med 2008;26:676–82. Chang AK, Bijur PE, Napolitano A, Lupow J, et al. Two milligrams i.v. hydromorphone is efficacious for treating pain but is associated with oxygen desaturation. J Opioid Manag. 2009 Mar-Apr;5(2):75-80. Sutter ME, Wintemute GJ, Clarke SO, et al. The changing use of intravenous opioids in an emergency department. West J Emerg Med 2015;16:1079-83. Miner JR, Kletti C, Herold M, et al. Randomized clinical trial of nebulized fentanyl citrate versus i.v. fentanyl citrate in children presenting to the emergency department with acute pain. Acad Emerg Med 2007;14:895–8. Furyk JS, Grabowski WJ, Black LH. Nebulized fentanyl versus intravenous morphine in children with suspected limb fractures in the emergency department: a randomized controlled trial. Emerg Med Australas 2009;21:203–9. Borland M, Jacobs I, King B, et al. A randomized controlled trial comparing intranasal fentanyl to intravenous morphine for managing acute pain in children in the emergency department. Ann Emerg Med 2007;49:335–40 Im DD, Jambaulikar GD, Kikut A, Gale J, Weiner SG. Brief Pain Inventory-Short Form: A New Method for Assessing Pain in the Emergency Department. Pain Med. 2020 Sep 11:ppnaa269. doi: 10.1093/pm/pnaa269. Epub ahead of print. PMID: 32918473. Mandel SE, Davis BA, Secic M. Patient Satisfaction and Benefits of Music Therapy Services to Manage Stress and Pain in the Hospital Emergency Department. J Music Ther. 2019 May 10;56(2):149-173. Piatka C, Beckett RD. Propofol for Treatment of Acute Migraine in the Emergency Department: A Systematic Review. Acad Emerg Med. 2020 Feb;27(2):148-160. Tzabazis A, Kori S, Mechanic J, Miller J, Pascual C, Manering N, Carson D, Klukinov M, Spierings E, Jacobs D, Cuellar J, Frey WH 2nd, Hanson L, Angst M, Yeomans DC. Oxytocin and Migraine Headache. Headache. 2017 May;57 Suppl 2:64-75. doi: 10.1111/head.13082. PMID: 28485846. Yeh YC, Reddy P. Clinical and economic evidence for intravenous acetaminophen. Pharmacotherapy 2012;32(6):559–79. Serinken M, Eken C, Turkcuer I, et al. Intravenous paracetamol versus morphine for renal colic in the emergency department: a randomised double-blinded controlled trial. Emerg Med J 2012;29(11):902–5. Wright JM, Price SD, Watson WA. NSAID use and efficacy in the emergency department: single doses of oral ibuprofen versus intramuscular ketorolac. Ann Pharmacother 1994;28(3):309–12. Turturro MA, Paris PM, Seaberg DC. Intramuscular ketorolac versus oral ibuprofen in acute musculoskeletal pain. Ann Emerg Med 1995;26(2):117–20. Catapano MS. The analgesic efficacy of ketorolac for acute pain [review]. J Emerg Med 1996;14(1):67–75 Dillard JN, Knapp S. Complementary and alternative pain therapy in the emergency department. Emerg Med Clin North Am 2005; 23:529–549. Hoffman BM, Papas RK, Chatkoff DK, Kerns RD. Meta-analysis of psychological interventions for chronic low back pain. Health Psychol 2007;26:1–9. Eisenhart AW, Gaeta TJ, Yens DP. Osteopathic manipulative treatment in the emergency department for patients with acute ankle injuries. J Am Osteopath Assoc 2003;103:417–421.

In the final episode of the year, David and Jessica discuss the Twisted Tea craze, if “New Year, New Me” is an oxymoron, and the one time David accidentally took Hydrocodone to treat the Flu. —Rush'd Vibes WebsiteSupport Your Folk clothing brand

Paul W was prescribed hydrocodone following a car accident… the beginning of a long journey with opioid pain pills. Living in Florida during the golden age of pill mills (early 2000s) didn’t help. After addiction, recovery, and relapse Paul moved to Italy where he met his future husband. They moved to England where Paul relapsed […] The post 39. Recovery in the UK with Paul W. first appeared on Kratom Science.

This episode of Drug Cards Daily is on the drug hydrocodone/APAP. Hydrocodone/APAP has a variety of brand names but most commonly known as Norco or Vicodin. It is a combination product containing an opioid and analgesic. Hydrocodone/APAP is typically used in the management of both acute and chronic pain. It comes in a tablet, solution, and elixir form. The main concerns are the potential for abuse, the CNS depressing effects, and not exceeding >4000 mg/day of acetaminophen (APAP). Constipation is a very common concern due to the opioid component so recommending a stool softener is highly recommended. Go to DrugCardsDaily.com for episode show notes which consist of the drug summary, quiz, and link to the drug card for FREE! Please SUBSCRIBE, FOLLOW, and RATE on Spotify, Apple Podcasts, or wherever your favorite place to listen to podcasts are. The main goal is to go over the Top 200 Drugs with the occasional drug of interest. Also, if you'd like to say hello, suggest a drug, or leave some feedback I'd really appreciate hearing from you! Leave a voice message at anchor.fm/drugcardsdaily or find me on twitter @drugcardsdaily --- Send in a voice message: https://anchor.fm/drugcardsdaily/message

Rod the Steelerworker is from Michigan and has been a steelworker for 24 years. As a young man his hobbies were skateboarding and 4-wheeling. As a result of those hobbies, a career doing repetitive physical labor, along with Degenerative Disk Disease, diverticulitis, and IBS, he suffers from chronic pain. A prescription to Norco led him […] The post 34. Rod The Steelworker Switches to Kratom From Norco for Chronic Pain first appeared on Kratom Science.

Today’s episode is an interview with Dr. Wendy Stephan, an educator and epidemiologist for the Florida Poison Information Center in Miami.  As a poison prevention advocate and educator, she shares important messages through storytelling.  **Listener discretion is advised.**  Some of the topics in this episode include children putting weird things in their mouths, poisoning, injury, death, medicine looks like candy, and more.  Again, listener discretion is advised. Dr. Wendy Stephan is the educator and epidemiologist for the Florida Poison Information Center in Miami.  For the past 12 years, Wendy has promoted the use of poison control and worked to prevent poisonings of all kinds, including from medication, household chemicals, and environmental hazards.  Wendy completed her PhD in Epidemiology and her Master of Public Health degree at the University of Miami and has previously chaired the Public Education Committee of the American Association of Poison Control Centers.   Website, e-mail, and social media links • Website(s): www.floridapoisoncontrol.org • Email: wstephan@med.miami.edu • LinkedIn: https://www.linkedin.com/in/wendy-stephan-phd-mph-315b70178/ • Twitter: @floridapoison Facebook: https://www.facebook.com/FloridasPCC/ Mentioned in the episode 1-800-222-1222 is the Poison Help Line (Poison Control) poisoncenter@fpicn.org = Florida’s Poison Information Center educators or call 1-800-222-1222. Institute for Safe Medication Practices ISMP.org is a non-profit organization dedicated to the promotion of safe medication practices.   FDA MedWatch adverse event reporting site:  https://www.accessdata.fda.gov/scripts/medwatch/  https://www.poisonhelp.org/help  https://www.webpoisoncontrol.org  Highlights  The Florida Poison Information Center in Miami partners with two other centers to serve the state of FL:  Jacksonville and Tampa.  The Miami location serves South Florida.  The Jacksonville location also serves the US Virgin Islands.   There are 55 poison control centers in the US.  Every state and territory has access to one.  Calls are geographically routed to a call center.  One poison center may serve multiple states. Contact your local poison center for prevention education. As a poisoning prevention advocate and educator, Dr. Wendy Stephan shares important messages through storytelling.  People in crisis have stories, which connect with people better than cold facts.  We are programmed as humans to learn through stories. She teaches pharmacy students.  Students enjoy interacting with the community. March is Poison Prevention Month.  The 3rd week of March each year is Poison Prevention Week.   The poison help line number is 1-800-222-1222.  Program it in your phone. Sometimes, law enforcement needs pills identified.  The poison help line is a great resource for pill identification because calls are recorded and can be used later (by subpoena) if needed. Teaching kids “asking behavior” is important.  “Mom and Dad, what about poison control?” Wendy’s work impacts all ages.  According to Wendy, working with caregivers and teachers is more helpful than working with toddlers because it touches more lives and avoids toddlers misinterpreting messages [about poisons].    Older adults and DD caregivers need Poison Control too.  For example, older individuals with poor vision who may be reading bottles in low light and have multiple medications are at risk for medication errors.  Organizations like Elder Affairs or an Area Office on Aging is a great place for pharmacists and pharmacy students to volunteer to speak about poison prevention.  Be careful:  don’t lecture, don’t stigmatize.  They know they’re taking a lot of medications.   Wendy realized she had a passion for poisoning prevention at the age of 6, when she saw a “Mr. Yuck sticker.”  As an adult, she started in poison prevention while working as an educator with Lora Fleming, a Marine Scientist.  Working at the FL poison center is like the Super Bowl for an epidemiologist.  It’s a once-in-a lifetime experience to be working in the field.   The COVID pandemic has affected injury epidemiology in FL: Hand sanitizer exposures (eyes, mouth) have increased compared to this time last year. Disinfectant exposures have increased. Bleach exposures have increased. [As a class,] household cleaning product exposures have increased. FL Poison Information Centers have helped the FL Dept of Health with their COVID-19 hotline.  Training and resources were provided quickly.  There have been >50,000 calls to the FL COVID-19 hotline so far. FL Poison Information Centers have seen an increase in calls about supplements and vitamins.  Ex:  vitamin C, vitamins in general, dietary supplements, and homeopathic remedies Pharmacists need to be aware that people are self-treating with OTC’s.  While patients are at the counter for counseling, ask if they’re taking anything or “mega dosing.”  Supplements can interfere with medications.   Who are Dr. Wendy Stephan’s coworkers?  Doctors, nurses, and pharmacists who are certified specialists in poison information (abbreviated C-SPI or SPI).  Her staff are 100% physicians in Miami. Wendy provides support to her coworkers and trains safety educators in the community.  Ex:  healthy start program home visitors who work with parents.  Ex:  foster parents and medical foster parents.  By reaching home visitors (people who work with parents), she reaches more parents.  It’s efficient. Works with other poison educators and colleagues around the state to design materials:  fliers, social media messages, etc.  Content relevant to the news gets good engagement.  It’s hard to get attention when you’re competing with other content. Two things that Florida has that Ohio does not have are snakes and aquatic toxins.  People fear snakes, but there are only ~6 bites per month from venomous snakes in FL.  Images of captured snakes in a bucket are something the FL Poison Information Center sees often.  Sometimes the Emergency Dept calls the Poison Information Center for support. Ciguatera Fish Poisoning happens in Florida.  This marine toxin can even reach Ohio when fish are transported.  Jelly Fish stings from the Portuguese man o’ war and the Box Jelly Fish are common too.  Marine toxins change over time, and some toxins can cause someone go into shock. Who do I call?  9-1-1 or Poison Control? Call 9-1-1 if someone is unconscious, having trouble breathing, having chest pain, there lots of bleeding, or there has been an intentional poisoning.  EMT’s will call the poison information center when needed.   Most 1-800-222-1222 poisoning calls usually present as  Someone swallowed something unusual Someone made a medication mistake.  At first, they seem fine, and there is no drama.  Even when symptoms are not immediate and dramatic, call for help!  Poison Control can walk people through symptoms that may develop.  Then, Poison Control makes follow-up telephone calls.  Ex:  toothpaste + milk = vomit that looks like cottage cheese, and that’s a good thing. Iron poisonings are serious and deadly because of multi-organ involvement.  Iron tablets can be attractive to children and may look like candy.  According to Wendy, child-resistant packaging slows a child down ~ 30 seconds.  Child-resistant packages do not guarantee safety.  Lock boxes help prevent medication-related poisonings in all ages.  Make it a habit to hide medications in a lock box.  20% of poisoning deaths are intentional due to depression or a moment of panic.  Lock boxes could slow someone down long enough for the self-harm impulse to pass. Prevention is for all ages.  Best practices: Don’t stockpile medications.  (Ex:  Hurricanes and emergency preparedness) Medications that are older and expired may cause confusion about who they’re for, or why they’re on-hand.  If you have forgotten it’s even in the home, it’s time to get rid of it. Drug disposal is important.  Use drug disposal programs and do routine “sweeps” and get rid of anything you don’t need.  Don’t accumulate dangerous and unnecessary meds in the home.  Some drugs are like time bombs in the home.  Ex:  Hydrocodone and teens or someone depressed due to loss of job.  Get rid of it!  It’s dangerous to keep around.  DEA Take Back Days are an option twice/year. Some communities pair drug take-back with “shred days” to prevent poisonings and identity theft as a 2-for-1 service. The National Poison Data System provides nearly real-time poison center data.  This information is reported to the Health Dept and the CDC.   Contaminated products Street drugs Confusing packaging on consumer products.  Placing a case report helps the poison center identify problems and respond or get the attention of someone who can respond/initiate a public health response.  Ex:  e-cigarettes. Is it better to call Poison Control or use a poison information website?  Poison information websites are available, but calls are better because diagnostic information can be collected by phone.  Ex:  slurred speech (impairment is present).  Ex:  hearing someone cough after a baby powder exposure.  If someone is hearing impaired, the websites can be a helpful alternative. A typical week for Wendy involves a mix of office and community work.  Building relationships is important.  She likes the variety and challenge. Wendy uses a visual aid with high school students, emergency room doctors, and others called the “Cookie Jar of Doom.”  It contains pictures or items to represent the 12 most deadly poisons in Florida.  It leads to great discussions.  Examples include: Carbon Monoxide Prescription drugs:  oxycodone, hydrocodone, methadone Illicit drugs/street drugs:  cocaine and heroin Benzodiazepines  No snakes, no spiders.  Nothing is alive in the jar.  The source of the items is data from the Injury Prevention Program at the FL Dept of Health on substances leading to deaths.  For more information, see the “poisoning data” tab on the Florida Poison Information Center website. Stories, games, and interacting with things physically are universally fun for everyone, and variety is good. What is the scariest poison?  Alcohol. Alcohol changes behavior and judgement, unlike many other poisons. Very serious cause of injury death Alcohol poisoning can result. Alcohol can lead to car crashes. Alcohol can lead to a fatal interaction with a weapon. Alcohol can lead to self harm. It’s the most stealth poison. Alcohol has been partly responsibility for 25% of deaths one year in FL.  It flies under the radar.  Children can’t metabolize alcohol, so they can easily become injured.   How (in general) can someone prevent a poisoning? Awareness of different poison hazards in the home. Prevent medication mistakes Prevent product exposures Look at the labels Store medications up and away above shoulder height in a cabinet with a closed door.   Drawers and shelves are not good places to store medication and household products.   Know what to do if something happens.  Call Poison Control.  Have the number handy.  Don’t “wait and see” when there has been a medication error.  Call right away. Knowing about “pretty poisons” and look-alike items is helpful. What does Dr. Wendy Stephan love most about working for the FL poison information center?  Great colleagues in FL and across all poison information centers and being in the community. What is a challenge she faces?  Getting the word out about their center and getting people’s attention.  People think, “it won’t happen to me.”   Calls to Poison Control are confidential.  There is HIPPA protection.  Poison Control fields plenty of calls from individuals suffering from mental illness.  Poison control centers don’t judge.  They don’t call child protective services either.  Some communities are fearful of children being removed from the home (suspected abuse).   Epidemiologists use data to understand the big picture.  Epidemiology drives effective interventions.  Injury data is important.  Talking about medication safety and alcohol will save lives.  Local, state, and national data drives effective interventions and actions public health epidemiologists make.   How can pharmacists help?  Be that trust professional who can educate people, share expertise, etc. because you have relationships with patients and key members of the community.      

Pure heroin currently costs up to $400 dollars per gram on the streets. But it only costs around $2 per gram to produce. The 40,000% profit margins go to street dealers and traffickers--the cops can't exactly sell it at auction when they confiscate it. This episode details the history, production and use of opium products. From Tramadol to Fentanyl--how strong is each drug, and how is it best consumed? From pills to injections--what dangers do drug users face in the ongoing war on drugs? From black tar heroin to "China White"--what's the difference, and where do these different forms of heroin come from? If you are looking for information about heroin, morphine, fentanyl or other opioids, this is the episode for you.

Vicodin Pharmacology https://worldsbest.rehab/vicodin-addiction/ Vicodin contains 500 milligrams of acetaminophen and five milligrams of hydrocodone. It comes in several forms including syrup, capsule, and tablet. Doctors prescribe Vicodin for individuals suffering from various forms of pain. Vicodin is a popular painkiller that has been glamorized over the years by films, television shows, and literature. Adding to Vicodin's popularity is the use of it by celebrities in their private lives and at one time, it seemed to be the prescription of choice by many doctors seeking to help patients living in pain. Unfortunately, many of the individuals who called upon Vicodin for help found themselves addicted to the painkiller. The painkiller can trace its roots back to the 1890s when the first medical use of acetaminophen was recorded. It wasn't until 1978, however, that German pharmaceutical company Knoll combined acetaminophen with hydrocodone to create Vicodin. Overnight, a wonder painkiller drug was created and by the 1990s, it was used by everyone seeking to be free of pain to individuals looking for a prescription drug as a high. Vicodin contains 500 milligrams of acetaminophen and five milligrams of hydrocodone. It comes in several forms including syrup, capsule, and tablet. Doctors prescribe Vicodin for individuals suffering from various forms of pain. Originally, it was used by patients as an alternative when other options didn't work. However, there was a time when doctors prescribed Vicodin without weighing other pain-relief options and patients grew dependent on it. Hydrocodone is sold under the brand name Vicodin, along with Norco, Lortab and others. All brands contain the same active ingredient, the opioid analgesic, oxycodone, as well as the active ingredients of Vicadin. Some people with hydrocodone addiction have an addiction to opioids that have similar effects in sufficiently large quantities, including morphine, codeine and heroin. This type of preference has both practical and psychological reasons, the researchers say. Hydrocodone binds to pain receptors in the brain, specifically known as Mu opioid receptors. If it binds to these receptors, pain signals are weakened or completely blocked. Mu opioid receptors are also responsible for the positive aspects of drug use, and when used repeatedly, the effects of opioids on the frontal cortex weaken the brain's ability to make decisions and regulate mood. When people try to stop or reduce the use of Vicodin, they find out how dependent their bodies have become on painkillers. It also introduces the feeling of “good” sensations or euphoria caused by opioids, which also encourages people to take the drug again. How to Treat Vicodin Addiction? Individuals experiencing Vicodin dependency should speak with their doctor. Users should talk to their doctors about reducing their Vicodin consumption. Patients may be prescribed a medication to help ease potential withdrawal symptoms. Some patients may be advised to take a tapered approach to end their dependency on Vicodin. Long-term Vicodin users should seek medical detox to wean themselves off of the addictive drug. Medication-assisted treatments (MAT) are available to users seeking to end their dependence on the drug. Methadone and buprenorphine are used as replacements for opioids. Vicodin Factsheet Support the show (https://worldsbest.rehab)

On May 30th at 12:30 a.m., officers responded to the 3400 block of Illinois in reference to a one-year-old child found wandering outside unattended. Upon arrival in the area, officers secured the child and began checking the neighborhood to determine where the child lived. Nearly an hour later officers were directed to a residence on Illinois where the child was believed to reside. Upon arrival at the residence, officers approached the front door, and as they did they noticed a prescription pill, determined to be Hydrocodone, sitting on the front patio accessible to anyone, including children. They then knocked on the door and made contact with a female, identified as 32-year-old Gabrielle Vasquez, the mother of the one-year-old. Ms. Vasquez appeared intoxicated and unbothered that her child was missing and had been found wandering the neighborhood for more than an hour, nor did she contact the police. Officers contacted the Harris County District Attorney’s Office and advised them of the case at which time charges of Endangering a Child were accepted on Ms. Vasquez, who was then placed under arrest and transported to the Baytown Jail. --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app Support this podcast: https://anchor.fm/newsnowbaytown/support

My guest is Suzette Prutsok from Southern California. Suzette is an abstract artist and screenwriter. She was addicted to opiates for years, and after a couple attempts, got sober and made a profound change in her life with the help of kratom. This is Suzette Prutsok, and this is her kratom story. Suzette Prutsok’s art […]

In today's episode: We hit a bunch of random questions from recently published trials.   Still trying to get CME approved through ANAWA medical clinics, just FYI

Welcome to episode 3 of the Lindsey Holder Podcast, with your hosts, Lindsey and Ashley! This is where you will gain tips on how to run a successful small business, and keep yourself looking good while you do it! Tune in today, to find out more! Are you struggling with unattractive brown marks on your face? If so, you're not alone because this is quite a common problem. Ashley has a patch of brown spots on her forehead and she remembers seeing similar marks on her mom's and her grandparents' faces when she was little. Back then, they used to call them ‘liver spots', although the professional term is actually hyperpigmentation.  Everyone would love to have an even, bright, and luminous skin tone, so in today's mini-episode, Lindsey and Ashley will be teaching you how to reduce the look of hyperpigmentation, both with lasers and without. Be sure to listen in, to find out what you will need to do. Show highlights: Most people want to have a bright, luminous, even skin tone. Hyper-pigmentation keeps you from having an even skin tone, and it can make you look a lot older than you are. Lindsey noticed that some of the pigmentation marks around her bikini-line became a little darker after she had laser hair removal done. Lindsey explains what she used, instead of laser-treatment, to effectively remove the dark pigmentation marks from around her bikini-line. Hydrocodone is a controversial topical ointment, and it has side effects, so you need to be aware of that if you decide to use it. Lindsey explains what causes hyperpigmentation. Some of the common ways that hyperpigmentation can occur. Hyperpigmentation is harmless. Facial peels remove the layers of skin with hyperpigmentation. Hyperpigmentation tends to creep back in once it has been removed, so it will need to be managed for the rest of your life. Some ways to keep hyperpigmentation from worsening. The cooler months are the perfect time to treat and reduce hyperpigmentation. The treatment is a combination of self-care and professional treatments. Doing things the right way makes a huge difference. Some ingredients that can lighten your skin. Some precautions that you will need to take when using ‘miracle creams'. Lindsey discusses some of the skin-lightening creams that are currently available. Ashley talks about laser treatments. They are effective but they are also quite costly. Some self-care treatments that you can do at home.  Links and Resources: Lindsey's website: Organic Tan Face and Body -  www.organictanfaceandbody.com   

Frances Addison examines how our quest to control and manage pain has led to a modern medical crisis, as opioids oxycodone and hydrocodone are among the most abused prescription medications in the US

On today’s show, we are talking about the opioid crisis, also known as the opioid epidemic, and its woeful impact on millions of American people and families. Opioid medications are commonly abused because of their addictive qualities. These medications bind to the areas of the brain that control pain and emotions, driving up levels of the feel-good hormone dopamine isn’t he brain’s reward areas and producing an intense feeling of euphoria. As the brain becomes used to the feelings, it often takes more and more of the drug to produce the same levels of pain relief and well-being, leading to dependence and, later, addiction. OxyContin, Fentanyl, and Hydrocodone are some well-known examples of opioids used today. Purdue Pharma, the pharmaceutical company that distributes many opioids in North America, is owned by the Sackler family, who have recently faced criticism and lawsuits amidst Purdue Pharma’s role in the crisis. The Sacklers are one of the wealthiest families in the country, with an estimated fortune of $13 billion. However, as part of a tentative settlement agreement in thousands of lawsuits over what accusers say is misleading marketing of Purdue Pharma’s painkiller, OxyContin, Purdue Pharma has recently filed for bankruptcy. The settlement requires members of the Sackler family to pay $3 billion of their own fortune in cash over the next 7 years. Who is truly at fault for this crisis: the creators of these drugs? Or the users themselves? Is it right to blame an addict for their addiction when the drug itself is nigh irresistible? What about those who were prescribed opioids for chronic pain following a major life-changing event, and are now saddled with addiction, high medical bills, and a bleak health future? Listen in to find out. --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app --- Send in a voice message: https://anchor.fm/harrietcammock/message Support this podcast: https://anchor.fm/harrietcammock/support

2019-55908 On Monday, September 23rd at 11:33 a.m., a family member reported 52-year-old Edward Oneil as missing. Oneil was last seen on August 27th at his residence in the 1700 block of Bob Smith. Oneil is described as a black male, 5’6” tall, 170 lbs., black hair, and brown eyes. He was last seen wearing a white t-shirt and blue jeans. Case is under investigation. 2019-55952 On Monday, September 23rd at 4:08 p.m., Baytown Police responded to the 1700 block of Gillete Drive in reference to a disturbance. Baytown officers contacted the complainant who reported 67-year-old William Murphy pointed a handgun at him because he used Murphy’s driveway to turn around. Murphy told officers he did not want the complainant using his driveway. The Harris County District Attorney’s Office was contacted and the charge of Aggravated Assault with a Deadly Weapon was accepted on Murphy. Mug shot attached. 2019-55955 On Monday, September 23rd at 4:12 p.m., Baytown Police responded to the 3400 block of Red Cedar Drive in reference to a disturbance. Baytown officers contacted the complainant who reported 23-year-old Rodney Eligon discharged a firearm into the ground. Officers contacted Eligon and he admitted to firing the weapon into the ground after a friend brought the gun to his residence. Officers contacted three subjects, who were visiting Eligon, sitting in a nearby vehicle. Officers searched the vehicle and recovered a backpack belonging to 24-year-old Alexandra Sanchez. The backpack contained the handgun used by Eligon along with marijuana, Ecstasy, Adderall, Vicodin, Hydrocodone and Xanax. The Harris County District Attorney’s Office was contacted and the charge of Possession of Controlled Substance with Intent to Deliver was accepted on Sanchez. Eligon was arrested for Baytown warrants. Sanchez and Eligon were transported to the Baytown Jail. Mug shots attached. 2019-56002 On Monday, September 23rd at 9:28 p.m., Baytown Police responded to the 700 block of Alford Avenue in reference to an assault. Baytown officers contacted the complainant who reported his girlfriend arrived home with a male in a vehicle. The complainant stepped in front of the vehicle in the roadway to prevent the driver from driving away. The unidentified male exited the vehicle and pointed a handgun at him then struck him in the head with the gun. The complainant later changed his story and could not confirm the details of this incident. 2019-56029 On Tuesday, September 24th at 2:19 a.m., Baytown Police responded to Circle-K, located at 7415 Garth Road, in reference to a robbery. Officers contacted the clerk who reported an unidentified male entered the store with a handgun. The male demanded money and left the store with $40.41 in cash. The suspect was described as a white or Hispanic male, 5’10” tall, wearing a black hoodie, white scarf covering his face, and wearing blue jeans. The male left the location in an unknown direction. facebook.com/newsnowbaytown twitter.com/newsnowbaytown https://newsnowbaytown.wixsite.com/home Donate to keep NNB going CLICK HERE --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app Support this podcast: https://anchor.fm/newsnowbaytown/support

The story of how illness and prescription opioid drugs dangerously come to together and the possible dangers when NOT abused.

In Episode 38 of Florida Men: The Podcast, Florida Woman Casey Anthony should just shut up already, a Florida Man should just give up already, a Florida Woman reminds Phil that Joel still owes him Waffle House, and a Florida Man steals the wrong pills.

A man in Florida stole some medication out of his roommate's lockbox. They were labelled Hydrocodone. But, they weren't. They weren't opioids. They were laxatives. And yes, he did find out the hard way.

Along with host Brian Fortenberry, Dr. Stephen Loyd discusses his intimate struggle with opioid addiction. For three years, Dr. Loyd was addicted to painkillers while working as a physician. In one hand, he had everything anyone would want in life. In the other, a handful of pills. He discusses how finding the Tennessee Medical Foundation helped get him out of addiction.

You've no doubt heard of it by now... In an attempt to live longer, some anti-aging enthusiasts are getting themselves injected with the blood of young humans, via a process deemed: plasmaphoresis. This podcast is about several age reversal therapies. It's also about biohacking Alzheimers. It's about all these therapies (senolytics, exosomes, gdf-11, etc) that scientists have been talking about for age reversal. The podcast is about biological aging clocks and biomarkers to measure them. You'll learn about ways that you can biohack Alzheimer's disease, how to measure your biological age, how to reverse aging, what the biggest obstacle to age reversal is, how to get more involved in the anti-aging community and more. About the Guests Mark Urdahl, is a technology entrepreneur from the Silicon Valley.  He has numerous patents and has worked in big data.  He began his career at IBM's medical instruments subsidiary that pioneered plasmaphoresis.  Mark founded  to advance new uses for well established therapeutic plasma exchange therapies which have recently evidenced a previously undocumented potential to rejuvenate the body's own stem cells, restore aging immune systems, and prevent the onset of many age-related disease condition, so that we might live healthy as we age and ultimately live longer lives.     Tom Ingloglia first appeared on this podcast in the episode ""  As you learn in that episode, Tom is a private investor with a master’s degree in finance. In the midst of trading, investing in technology and developing real estate in Costa Rica, Tom became very sick. He was initially prescribed antibiotics, suffered from an adverse reaction and was told that he’d have stomach problems for the rest of his life. In the years that followed, Tom also developed severe food allergies. His symptoms worsened, and he next began dealing with insomnia, anxiety, muscle pain, tendinopathies, joint pain, chronic fatigue syndrome, altered and clouded cognition and headaches. He finally had a mental breakdown in 2008. After a prolonged period of taking antibiotics, Tom began experiencing tendonitis throughout his fingers, hands, wrists and ankles and feet, so he started taking pain medications to relieve this pain. He had to give up his career in trading because his sole focus for the next eight years would be on finding a cure to his growing symptoms. His life consisted of working with physical therapists, going to the gym, going to new doctors, and trying new foods to see if it would help. Throughout Tom’s eight-year battle, he was prescribed consistently and persistently more medication. For six years, he was taking excessive amounts of Hydrocodone and Tramadol every day. Tom became obsessed with researching symptoms and treatments, and learned about the NAD+ treatment. He visited a clinic, and on Day 7 of his treatment, “It hit me. I started feeling better. I felt amazing. There was a calm that came over me. I felt safe. I just had no cravings for drugs or pain meds. There was no need for them. I just didn’t have the excruciating pain that I had before. I felt eight years of pain melting away.” Tom has nearly fully recovered, using related treatments to NAD+, and has engaged two cofounders to assist him in building out a facility to help bring this treatment to others in similar situations. In my conversation with Mark and Tom, you'll discover: -The history of and how "heterochronic plasma exchange" works...16:00 Heterochronic plasma means simply removing old plasma and replacing it with "young" plasma. Others are experimenting with this concept. What Mark does is different from a plasma "infusion." Plasma is approximately half of our blood volume.  Mark began with IBM Biomedical Systems, who had invented what we now call the "blood cell processor." -The intricate means of testing used on mice...22:15 Basically creating "siamese twins" with mice by stitching them together. Similar procedures have been conducted on humans for over 50 years. Mark wanted to recruit the best medical professionals to the Young Blood Institute. Many of them have been doing it for 30-40 years. -What, if any, are the risks of these plasma exchanges...29:10 Roughly a 4% risk of a transfusion reaction, which is akin to what you might experience donating blood. One of the safer procedures in the medical field today. You go through 6 exchanges as part of a protocol. -The network of doctors that Mark and Tom have built to do a plasma exchange...32:42 There are medical professionals all over the U.S. that can do the procedure. Submit an inquiry on the website to find a doctor that is near you. -What anti-aging biomarkers Mark is tracking at the Young Blood Institute...34:51 They have more technology testing capability than Stanford, Johns Hopkins and Harvard combined. Key technology: time of flight mass cytometry. Single cell proteionomics. They are trying to develop early detection biomarkers that enables them to prevent the onset of diseases before they become significant. -The lowest hanging fruit for people to track...46:15 The YBI's concern is the function of the body, rather than the age. Your cells are not aware of your "age". -What a biological aging clock is...50:20 Zymo is a lab that has worked with Steven Horvath.  Looked at DNA, and seen a pattern from methyl groups attached to certain parts of the genome. -How can we track biological aging, or slow down our biological aging clock?...52:30 Inflammatory markers, heart age, brain age, lung age, skin elasticity. -The anti-aging booth that Mark and Tom will be operating at a conference called RAAD Fest...54:45 Want to have a contest where people calculate their age, and track their progress. Mark and Tom have one of the largest booths at the conference. -Whether NAD actually gets absorbed into a cell via injections or IV...1:00:30 How does Ben feel with an injection? Answer: Incredible. Tom doesn't recommend the injection due to the level of discomfort. -Why compounded formulas such as glutathione and Vitamin B could be taken off the market soon...1:07:30 There's a review similar to a court hearing, where people argue for and against glutathione. Taken off the market for compounding pharmacies. Tom "has his own reasons" for why this could be deemed unsafe. Core problem: the vitamins don't have any intellectual property. Could affect the costs of healthcare. -How to use technologies such as Vielight and exosomes to address Alzheimer's...1:14:30 Alzheimers is a $500 billion industry; the 6th leading cause of death. A Vielight is basically a laser light for your nose and head; photobiomodulation on your skull. -What GDF11 mRNA is and how it works to improve hearing, smell and sight...1:25:30 GDF11 is a DNA repair molecule; makes stem cells active again. Patients see improvements in sex drive, vision, smell, hearing, etc. Legal hurdles to being able to administer it. "Unofficial" results are very positive. -How senolytics works as a therapy for aging and Alzheimer's, and the importance of quercetin and tocotrienols...1:33:45 Describes small molecules that lead to the death of "zombie" cells that don't help the rest of your body.  "Natural Compounds that Remove Aging Cells" -And much more... Resources from this episode:  - - - - - - Use discount code "BenlovesNAD" at check out - - - - - - - - - - - -Book:  by Dr. Dale Bredesen - -Exosomes Podcast:  - - - - - - and  - 500-800mg Quercetin and 150mg tocotrienols per day for 3 months - Episode Sponsors: - Whether you’re looking to stimulate faster muscle growth, recover more rapidly from exercise, become more resistant to fatigue during a grueling workout, or just benefit from additional amino acids in their most absorbable form to support aging or a vegan, vegetarian, or ketosis diet, Kion Aminos essential amino acids has you covered. - "How to eat gluten and get away with it..." Get 10% off the already discounted price when you use my link! - Makes healthy living easy and affordable at 25-50% off traditional retail prices. Use my link and get an additional $60 off your order. - The revolutionary bedroom biohack for guys who want optimal sexual performance. Do you have questions, thoughts or feedback for Tom, Mark or me? Leave your comments below and one of us will reply!  

On this episode, I discuss the pharmacology of hydrocodone.  We also cover adverse effects, clinical use, and important genetic and drug interactions.  Enjoy the show and don't forget to subscribe to the podcast and receive a couple of free gifts!

Thomas Ingoglia joined Mark Young at RAADfest 2017 to talk about NAD (Nicotinamide adenine dinucleotide), a molecule showing great potential for its anti-aging effects, as well as helping people with addiction recovery and chronic health conditions. Ingoglia discusses the treatments available at the NAD Treatment Center, describing what people wanting to maintain their health would get out of the intravenous infusion of NAD offered. This includes an increase in energy, pain reduction, increased physical performance and more. He also suggests what a person should do in order to live beyond 120. Listento the Ben Greenfield Fitness podcast with Ingoglia about NAD. Learn moreabout the NAD Treatment Center and follow them on Twitter @NADTreatmentand on Facebook. About the guest: Thomas Ingoglia is the business director at NAD Treatment Center. He is a private investor with a master’s degree in finance. In the midst of trading, investing in technology and developing real estate in Costa Rica, Tom became very sick. He was initially prescribed antibiotics, suffered from an adverse reaction and was told that he’d have stomach problems for the rest of his life.  In the years that followed, Tom also developed severe food allergies. His symptoms worsened, and he next began dealing with insomnia, anxiety, muscle pain, tedinopathies, joint pain, chronic fatigue syndrome, altered and clouded cognition and headaches. He finally had a mental breakdown in 2008. After a prolonged period of taking antibiotics, Tom began experiencing tendonitis throughout his fingers, hands, wrists and ankles and feet, so he started taking pain medications to relieve this pain. He had to give up his career in trading because his sole focus for the next eight years would be on finding a cure to his growing symptoms. Tom’s life consisted of working with physical therapists, going to the gym, going to new doctors, and trying new foods to see if it would help. “I was in the prison of constant pain, and would try anything, any place, that might help.”   Throughout Tom’s eight-year battle, he was prescribed consistently and persistently more medication. For six years, he was taking excessive amounts of Hydrocodone and Tramadol every day. Tom became obsessed with researching symptoms and treatments and learned about the NAD+ treatment. He visited a clinic, and on Day 7 of his treatment, “It hit me.  I started feeling better. I felt amazing. There was a calm that came over me. I felt safe. I just had no cravings for drugs or pain meds. There was no need for them. I just didn’t have the excruciating pain that I had before. I felt eight years of pain melting away. Tom’s pain began to dissipate, and he started getting his energy back. “I was so paranoid of relapses, because they had happened in the past, but over the course of the following months I started feeling better, just as the clinic had predicted. Finally, I got my sanity back.” More than a year later, Tom has nearly fully recovered, from both his illness and his cravings for pain medications. He’s immersed himself in better understanding the NAD+ that saved his life, along with related treatments, and has engaged two cofounders to assist him in building out a facility to help bring this treatment to others in similar situations.

The Centers for Disease Control and Prevention (CDC) recently reported that for the second year in a row the life expectancy in the US has declined - a change that is largely influenced by an increase in drug overdose among young people.  Everyone in every community has been affected by addiction in one form or another - an alcoholic parent, a teen in rehab, or maybe a spouse addicted to pornography. Erik Kerr, the Co-Founder of Clear Health Technologies is here to talk about the massive impact addiction has on the lives of 282 million people worldwide.  He and Summer Felix-Mulder have brought together 29 amazing speakers on healing all facets of addiction and facilitating lifelong recovery.  It’s a free online 7-day event called the Healing Addiction Summit, and it starts February 3rd. Here’s the outline of this interview with Erik Kerr: [00:00:40] The Draw Shop. [00:02:25] The Keto Summit. [00:03:02] $35 billion spent on addiction treatment and support. [00:04:15] Almost 100% failure rate. [00:06:21] HeroX Challenge: Addiction Relapse Technology Challenge. [00:07:49] 282M affected. [00:09:26] Addiction definition. [00:10:12] Opiates, alcohol, sex. [00:10:33] Hydrocodone, Oxycontin. [00:12:11] Rating doctors by pain management. [00:12:55] Rachel. [00:14:42] Dr. Mary Caire. [00:16:35] Social media and phone use. [00:17:30] One year no beer. [00:17:48] Are you leading by example? [00:20:24] Dopamine resistance and porn. [00:20:46] Dr. Nora Volkow, Director of the National Institute of Drug Abuse (NIDA). [00:22:04] Prefrontal cortex is not fully developed until 25 years of age. [00:23:30] Time spent watching porn (actually closer to 9 minutes, rather than 7  as we said in the audio). [00:25:58] Podcast: The Hungry Brain with Stephan Guyenet, PhD. [00:26:13] Dr. Mark Hyman. [00:26:50] Study: Gesch, C. Bernard, et al. "Influence of supplementary vitamins, minerals and essential fatty acids on the antisocial behaviour of young adult prisoners." The British Journal of Psychiatry 181.1 (2002): 22-28. [00:31:15] Parenting. [00:32:49] Allison Hudson. [00:34:36] 1 in 10 babies born in West Virginia is a crack baby. [00:35:45] Robert Sapolsky. Video: Human Nature and Ted Talk: The Biology of Our Best and Worst Selves. [00:38:51] Podcast: How to Create Behavior Change, with Simon Marshall, PhD. [00:40:18] Dr. Nora Volkow. [00:41:53] The Healing Addiction Summit.

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Dogma often dictates routine care. There are times when we have to attend to paradigm shifts. An easy way to save lives?  Just say no to (these) drugs: Codeine Normally metabolized into codeine-6-glucuronide (50-70%) and norcodeine (10-15%).  Codeine, codeine-6-glucuronide, and norcodeine have low affinity for the μ (mu) receptor. However, the most active metabolite of codeine is morphine with 200x the affinity for the mu receptor as the codeine derivates.  The problem is, people vary in its metabolism from 0-15% of codeine is metabolized to morphine. Ok, codeine is lame at best, unpredictable at worst. True.  Unless you are hiding a genetic time bomb. You're an ultra-rapid metabolizer. Some people have multiple extra copies of the DNA sequence for the CYP2D6 enzyme.  Ultra rapid metabolizers funnel a huge proportion of their codeine into morphine metabolism, resulting in a bolus of morphine, ending in apnea. Promethazine with codeine This combination is no better than placebo -- all of the risks, with no proven benefit.  This combination is notoriously abused -- as purple drank or sizzurp.  The rapper Pimp C died of this. Speaking of cough syrups... The AAP recommends no cough and cold preparations in children under age 6.  They have not been adequately studied in young children, and are not recommended for treating the common cold. What then?  You gotta give me something, doctor! Ok, Honey! In a study in the Archives of Pediatric and Adolescent Medicine, Dr Paul and colleagues published: Effect of honey, dextromethorphan, and no treatment on nocturnal cough and sleep quality for coughing children and their parents.  They compared a buckwheat honey, honey-flavored dextromethorphan (DM) and no treatment 30 min before bed for children with upper respiratory tract infections. Of the three, honey, dextromethorphan, and no treatment – honey scored the best for symptom improvement and cough frequency. Over age 1?  Cough and cold?  Honey.  There is no concern about accidental overdose, parents are doing something with a proven effect, and compliance is pretty much 100% -- and Grandma approves. Dextromethorphan No proven benefit over placebo.  Also widely abused, in pill form ("Skittles") and/or liquid form mixed in alcoholic beverage ("robotripping"). Alternatives to Codeine Details in Audio: Morphine liquid Acetaminophen and Hydrocodone   PEARLS AND PITFALLS IN PEDIATRIC PAIN Allow the child to speak for himself whenever possible. After acknowledging the parent’s input, perhaps try “I want to make sure I understand how the pain is for you. Tell me more.” Engage parents and communicate the plan to them. Elicit their expectations, and give them of preview of what to expect in the ED. Opioids are meant for pain caused by acute tissue injury, for the briefest period of time feasible. Older school-aged children and adolescents are increasingly at risk for opioid dependence and addiction. Give detailed advice on how to manage pain at home. Set expectations. Let them know you understand and will help them through your good advice that will carry them through this difficult time. Patients and families often just need a plan. Map it out clearly. And... Just say no to: codeine, promethazine with codeine, and dextramethorphan. Selected References Dhaliwal G, Hsu D. Tramadol Ultra Rapid Metabolizers at Risk for Respiratory Depression. Pain Physician. 2016; 19(2):E361. European Medicines Agency. Restriction on the use of codeine for pain relief in children—CMDh endorses PRAC recommendation [press release]. June 28, 2013. FDA. Most Young Children With a Cough or Cold Don't Need Medicine. Hartling L et al. How Safe Are Common Analgesics for the Treatment of Acute Pain for Children? A Systematic Review. Pain Res Manag. 2016; 2016: 5346819. Grond S, Sablotzki A. Clinical pharmacology of tramadol. Clin Pharmacokinet. 2004;43(13):879-923. Jin J. Risks of Codeine and Tramadol in Children. JAMA. 2017 Oct 17;318(15):1514. doi: 10.1001/jama.2017.13534. Kelly LE et al. More Codeine Fatalities After Tonsillectomy in North American Children. Pediatrics. 2012; 129(5). Kirchheiner J, Schmidt H, Tzvetkov M, et al. Pharmacokinetics of codeine and its metabolite morphine in ultra-rapid metabolizers due to CYP2D6 duplication. Pharmacogenomics J. 2007;7(4):257–265 Orliaguet G et al. A Case of Respiratory Depression in a Child With Ultrarapid CYP2D6 Metabolism After Tramadol. Pediatrics. 2015; 135(3). Poonai N. Analgesia for children in acute pain in the post-codeine era. Curr Pediatr Rev. 2017 Aug 28. doi: 10.2174/157339631366617082911563.1.   This post and podcast are dedicated to Bryan Hayes, PharmD for his practical approach to pharmacologic conundrums and to David Juurlink, MD, PhD for his steadfast dedication to patient safety and clinician education.  Check out Bryan's helpful blog and clinical resource, PharmERToxGuy.  Check out David anywhere one utters the word Tra-ma-dol.

Anxiety as it relates to drinking is discussed.  Alcohol suppresses the nervous system.  It is a depressant.  If we depress the nerves for long periods through binge drinking, our body reacts once the alcohol is gone by releasing adrenaline to compensate.  This gives us severe anxiety in return.  Which totally unbearable, and creates a fear that grabs you right in the chest. Aaron, with 16 days since his last drink, shares his story   SHOW NOTES   [11:12] Paul Introduces Aaron.  I’m 38; I live in Albuquerque NM, I work at a print shop.  I’m separated, I used to like to fish, and want to get back into that.  I like to be out in nature.  I have a miniature pincher named Packer.      [13:29] Paul- How is it different this time?   Explain that feeling that something clicked.   Aaron-  My body was telling me with the anxiety and the insomnia.  It wasn’t fun anymore.  I was drinking miniatures while I was at work, and tried to hide all the time.  Tired of being tired.  I’m 38 years old, the party is over already.   [26:13] Paul- Talk about your experience with Opioids.   Aaron- I started off with the pills.  Hydrocodone etc.  Then I started doing oxy, and for a few years I was doing that.  I was going through withdrawals because I couldn’t get them.  I started going to the clinic and got on methadone.    [30:28] Paul- 16 days ago you were sick and tired of being sick and tired.  What happened, and how did you do it?   Aaron- I started downloading and listening to podcasts.  I was trying to figure out what this was, and how to stop.  I jumped into it with both feet.   I went through the tough first few days of detox.  I stopped doing things that were triggering me.   [37:00] Rapid Fire Round What was your worst memory from drinking? Waking up in a Virginia jail, and couldn’t bond out because I was considered a flight risk.  Did you ever have an “oh-shit” moment? The time I was in San Diego and hit that show and ended up in jail in another state. What’s your plan moving forward? I’m going to hit the podcast circuit.  I’m going to create a program that will work for me.    What parting piece of guidance can you give listeners who are in recovery or thinking about quitting drinking?  Stop beating yourself up.  Don’t try to think ahead too far.   You might be an alcoholic if get pulled over in your work car going the wrong direction down a one way road and you didn’t know until you read the police report the next day.   Resources mentioned in this episode:  Anatomy of an Epidemic- By Robert Whitaker Connect with Cafe RE- Use the promo code Elevator for your first month free Sobriety Tracker iTunes Sobriety Tracker Android Sober Selfies! - Send your Sober Selfie and your Success Story to info@recoveryelevator.com     “We took the elevator down, we gotta take the stairs back up, we can do this!”  

A woman died after she was prescribed a deadly cocktail of drugs. She was prescribed Hydrocodone, Xanax and Soma and left the pharmacy with a total of 510 pills. Her doctor, Regan Ganough Nichols, a pain management doctor, has been charged with second degree murder in her death as well in the deaths of four other patients.

The boys talk about E3 and cover the burning question of why doesn’t Denzel like having things explained to him. Patreon: patreon.com/realnerdhoursIntro/Outro by: wauterboi (@wauterboi, twitter.com/wauterboi)twitter.com/xRealNerdHours is co-hosted by Denzel Walkes (twitter.com/thatdenzel) and…

The boys talk about E3 and cover the burning question of why doesn't Denzel like having things explained to him. Patreon: patreon.com/realnerdhours Intro/Outro by: wauterboi (@wauterboi, twitter.com/wauterboi) twitter.com/xRealNerdHours is co-hosted by Denzel Walkes (twitter.com/thatdenzel) and Chet Brown (twitter.com/BushidoBrownSD) Holler at the voicemail line: (413) SAVAGE-1 Email us at: askrnh@gmail.com Join the Subreddit: www.reddit.com/r/RealNerdHours/ Like us on Facebook: facebook.com/realnerdhourspodcast

I've only been in Bali five days and I already feel blissed out. I've had four massages, two meditation sessions, one surf lesson, two yoga lessons and a 4.5 hour pampering session! And I TOTALLY needed this, because the last month or two has been pretty cray-cray. As you may remember in my previous episode called Changing Plans, there's been quite a few plans that have been changed, including now owning a lifestyle property and getting a puppy for my birthday. Yes! My lovely man Josh has gone ahead and put a deposit on a white German Shepherd. So when I get back to New Zealand on April 5th, it's going to be all go - moving into the house, getting it furnished, setting up our new base and waiting on the puppy. I was content to go hard out on the organizing, planning, doing and making shit happen on all fronts, because I knew I'd be having this relax time in Bali, and of course my upcoming business sabbatical starting April 1st. If you've never been to Bali, let me just tell you this island has a very special energy to it. It's renowned for being a vortex of feminine energy. So for females in particular, when you're here you have this sense of being grounded, feeling strong, sensual and in your feminine power. Everywhere you look there are lush trees, green rice fields, beautiful flowers, street dogs, friendly Balinese people smiling, scooters whizzing by, yoga studios, cute cafes, healthy juices galore and many relaxed looking foreigners who are whiling their days away doing not a lot of anything much. Which is why Bali is the perfect island to come and unwind, de stress and lose yourself, or find yourself depending on what you're here to do. But obviously we don't all have the opportunity to buggar off to Bali when we feel like it do we? So it got me thinking: Why can't we have a mini vacation each and every day to get some of the same affects of a longer vacation? Why do we have to book in holidays months, and for some people, years in advance? Why all this waiting when we have the power and ability to take a break right now? In a Huffington Post article by Jill Ferguson she lists the benefits of vacations as: Reduces stress - as I can attest to, vacations help shrink stress and anxiety while boosting the mental and physical health of you and the entire family, if you happen to be vacationing with them. Helps your heart stay healthy - no really. In a 20-year study, researchers found that women who took a vacation once every six years or less were almost eight times more likely to develop coronary heart disease or have a heart attack than women who took at least two vacations per year. Improves your mental health (especially if it's longer than 2 weeks) because you're less tense, have higher energy levels and more positive emotions, fewer negative feelings and less depression. Improves your relationships because families or couples who vacation together undergo shared experiences, communication and togetherness, escape and relaxation and experiential learning, all of which contribute positively to well-being and to relationships. You may have heard me talk about taking a mid week weekend. I mean why wait for the weekend to experience one, but what about a daily vacation? That's a novel thought right? I dug into this idea with my dear friend Jaime Masters, of Eventual Millionaire fame, who's with me here in Bali. We planned this holiday in late 2016 when she found out she got asked to speak in the Philippines, just before my Freedom Mastermind Retreat I hold in Bali each year. So this was our window of time to fly into Bali at the same time and enjoy 9 days together. And we are doing that extremely well. Jaime is a single mother of two with an extremely successful and busy coaching and mastermind business. She's also a self prescribed geek when it comes to maximizing time efficiency and more recently bio hacking - do it yourself biology optimization, so to speak. Or as Jaime puts it - how to be a badass. So here's our jam session on how to optimize your day and also how to take mini vacations through a variety of suggested activities we do, and that we also think should be on your list. Natalie: So this is exciting! We are recording this in our lovely little room in Ketut's Place in Bali in Ubud and there's thunder and lightning happening and rain. This is cool. I am sitting on the bed as you do, with my girl, Jaime Masters and we've been talking a lot over the last couple of days about treating yourself because yesterday we had a four and a half hour pamper session! Thanks to Jaime, an early birthday present and it was amazing. And I was like, "Why don't we do this all the time?" and then I think actually if you did that all the time you'd just be in bliss zone and you wouldn't get anything done. Jaime: I think it can get boring after a little while. Natalie: Yeah, but it was pretty amazing. Like we had several massages, we had a facial; we had pedicures, manicures, head massage, hair treatment, body scrub. And I was in and out of states of bliss, in an out of state of sleeping, dreaming, imagining, ideating. It's beautiful. But what I want to just chat to you about, because I think you are really good at this with your full-time roster of amazing clients that you coach over at Eventual Millionaire and your business and your full time podcast where you are interviewing millionaires all the time. I mean you have one of the busiest schedules I know off plus you are a mom, full-time mom. So do you want to just share a couple of the ways you treat yourself throughout the day because I think you do this really well. Jaime: So first of all anybody that says that they don't have time, means that they don't want to. There is a great quote about that by Lao Tzu. "Time is a created thing. To say 'I don't have time,' is like saying, 'I don't want to." ? Lao Tzu So out of everybody I know, I am extremely busy. We need that time because we go crazy and nutso and when you get on that roll you are not efficient or effective in anything you do. So lessons learned from me sort of going a little insane, to children, and to my business and everything else has led me to actually taking the time in between. Even 15 minutes of going, "Ah! This is just for me and I don't have to do anything else." So we talked about meditation before and I definitely do meditate a lot. Sometimes in small spurts. Like I literally was just meditating for fifteen minutes while you were on the phone just now, because I feel like it gives me a deeper state of relaxation. I do that throughout the day quite often even at home in-between calls. But just trying to take that time where you can actually shut off whatever you're crazy entrepreneur brain is saying and go, "Okay this is time that I don't actually have to think about that", because otherwise we will. Our brain will just keep going forever and ever and ever. And so trying to pull those pieces out as best as you can, you know what I mean? Natalie: And I think we started discussing this from the minute I landed in Bali and I think you did too. We've both come off some pretty hectic schedules, me with house buying and packing up and book writing and helping my mom move and you with speaking in the Philippines, and having to do all the work around that as well. I think we both got to Bali and we are just like, 'ahhhhhhh' and I just noticed instantly how my mind just quietened and I've done more yoga and massage in the last two days than I had probably in the last months. So why don't we roll through, like kind of spit-fire out some of our favorite at home mini vacations we take during a pretty busy working day? Jaime: Okay so for me, I have a routine at the beginning. I literally wake up before my kids wake up now, 5:30am in the morning. I am not a morning person as much as Hal Elrod told me to wake up in the morning. I was like, "No I don't think so." It's literally only been the last four months or so. Beforehand I would meditate right after I brought them to school, but I realized that it wasn't quite enough for me and I kept feeling like I had too much to do throughout the day when the kids are at school so I moved it. And so far so good. I'm going strong but I am not a morning person! Natalie: Thunder. If you have any of this, this is real Bali in the background. Just making it real. Jaime: That was number one, so that was an evolution in my process. I have been meditating for a very long time and I was never like, "I have to meditate every day." It's just I wanted to, I wanted to. It is something that I pull out. I also do probably five to fifteen minutes in between whenever I am feeling overwhelmed or brain dead. So when I do a lot, I batch everything and so whenever I do client calls, sometimes I'm like, "How can my brain stop functioning like it should?" and being in states of flow are way more productive in general, so I try and figure out ways. There's a good book called Stealing Fire, it talks about hacking into the flow state that I was telling you a little bit about. What can we do that makes us feel so much better that we can come back and hit the ground running instead of just feeling horrid and crazy? Just what we were talking about this before too, like all day long nutso. And so I'll do that, I have a pool in the back sometimes when it's nice out, I'll go jump in the pool and reassess things, especially during the day when I'm actually working on stuff. At night time I'll definitely go, "This is my time! I am going to have a bubble bath. I am going to do whatever I can possibly do to turn that piece off". Because we don't make a conscious effort in general to turn it off. Natalie: A bubble bath is so good. I am looking forward to potentially buying a spa and having a spa pool for night time relaxation. I like the idea of a sauna, whether you go to one or have one at your place. Often gyms have a sauna so just even ten minutes sweating it out and just being present with your body is pretty amazing. Other things are just dropping into fifteen, twenty, or a thirty minute yoga session during the day, and I love starting with five minutes of downward dog because it ultimately ends up being a lot more, and just giving yourself that space. Also, when I have a dog which I am getting soon! I would just have cuddle time with my dog. I'd literally have a play time, go outside, throw the Frisbee, throw the ball, play. You've got kids around you, you'd grab them, play. Jaime: That's a funny thing. So sometimes I'm so back-to-back I like walking into the mailbox it's like my time. I literally go, "Okay I need some sun. I am going to go walk outside", because I literally only have like five minutes, like literally I am so scheduled. No matter what the time is, it doesn't matter I think it's the intention behind it that makes a huge difference. Because sometimes you can play with your dog and be like, "Oh that still didn't really help." But if you are really intentional about it, it makes-- Natalie: Throw the phone away for a minute. Jaime: As hard as it is. Natalie: Get back to nature. Sometimes just actually being outside and getting sun on your face is a really beautiful thing and just tune into the sounds around you. Jaime: I go and I lay in my backyard. I have the pool and I will go and lay on the bed and feel like, because we have an outdoor bed, just sit there for five minutes and not even have to do a meditation or anything like that, but just sort of soak in the sun. Natalie: The Vitamin D. Jaime: Sometimes I need that big time. And then being able to sort of go; "Now I reset. Now I can go back in". Very helpful. Natalie: We should caveat this with the fact that you are very efficient with your time. So it's not like you ever say, "I am really busy." You are fulfilled. You are busy but I as you said you batch things. Do you want to maybe talk people through kind of your working week so that... they do hear that you have time off, and time out and you are really good at, oh we didn't even mention it, you get regular massages? So do I but you get them every single week, yeah? Jaime: Oh yeah. Natalie: I think if you can you should even if it's half an hour. Jaime: Well this is the thing I kept going, "Oh I don't have the time because I have kids and I can't... when can I get a massage when I don't have them. We'll I have to work during the school hours". All that craziness goes on in your head. Let me just say, everybody can solve every problem pretty much. So my massage person comes in at their bed time, my kids go to bed, massage person comes in and I literally go to sleep right afterwards. Natalie: They come to your house? Jaime: They come to my house. It's not anymore expensive either. And they will do it like nine o'clock at night which is insane. Natalie: And then you just go to sleep? Jaime: I just go to sleep. It's like the best ever. It's amazing but it's because I am so scheduled and so intentional with my time. Because this is the thing too, it's not like I don't take a time off with the kids, it's that I have to be super effective whenever I am doing whatever I am doing. I have a lot of things going on so a typical schedule for me ,and I make my clients do all this too. I call it the master's schedule: Mondays are meeting days, back to back meetings like literally, with my masterminds, with my personal scrum from my team. Tuesdays are coaching days. Wednesdays, every other Wednesday is an interview so either back to back millionaire interviews or back to back me doing interviews on other people's podcast and then the rest of the week is free. So it's 'working free' so within the time my kids are in school which they get out at three thirty. Then I have open space that I can actually fill in advance because I am one of those people. But usually when I have the kiddos I'm done at three and then I don't work again unless it's like a crazy launch and I have to make an exception. It's me like going for a walk with the kids or I try and get some of the more special, relaxing kind of time with them. Not that I don't have to do homework, not that I don't have to do all the other stuff, but it's just trying to have that space within the confinement. How to take a quick daily vacation Alright hopefully you have some firm ideas on how to take a daily mini vacation. To recap: Short bursts of exercise - dance, walk to the mailbox, dip in the pool, play with your dog, drop down and do yoga. Treat yourself - have a massage or a sauna, at home or book it in at your local. Read a book - jump in a hammock, laze on your bed, lie on the floor, curl up in the couch, throw your phone away and disconnect the internet for 30 mins...then enjoy your fave book. Pleasure yourself - did I really just say that? Heck yeah I did. Have a quickie, grab your fave sex toy and take a moment to...you know...have some fun. Or grab your partner and kiss them passionately. It releases endorphins which are feel good hormones and everyone needs those - plus you do that stuff on vacation right? So this IS a mini vacation. Meditation - refer to episode 2 - Mind Your Mindfulness for a 1 minute one! They say meditation can be better than sleep and sometimes sex. So I think it's time to really take this one seriously. Before we bring back Jaime, as she's been delving into meditation for almost a decade but has upped her game in the last year with amazing results, let's say hello to Freshbooks The working world has changed. With the growth of the internet there's never been more opportunities for the self-employed. To meet this need, FreshBooks is excited to announce the launch of an all new version of their cloud accounting software! It's been redesigned from the ground up and custom built for exactly the way you work. Get ready for the simplest way to be more productive, organized, and most importantly get paid quickly. The all new FreshBooks is not only ridiculously easy to use, it's also packed full of powerful features. Here are just a few of the ones Jessica Broome, entrepreneur and Freshbooks customer loves: Go to freshbooks.com/quest and check out their full list of amazing features then sign up and save yourself time and money today. Just enter Quest For Freedom where it says 'How did you hear about us'. Ok, let's dive into meditation. So on a couple of the previous episodes I've been talking about meditation. And I have to say that I think we've only just scratched the surface on this and I am going to be doing a lot more work around this. But having chatted to Jaime over the last couple of days intensely around her her meditation practice, I've seen this different side to it so I think I've always sat on the surface going, "What if I could just get five or ten or fifteen minutes a day?". I know the benefits of meditation but I wanted to bring Jaime back because she's just sort of open my mind and blown my mind with the routine and the practice and the intention behind her meditation and how much is that impacting everything else. So I haven't seen Jaime for a year and a half and this time around seeing her I turned up and I was like, "Oh my gosh! You are just more like grounded." So here's a conversation we had about her meditation. Natalie: So who is this Joe Dispenza guy that you keep going on about? Jaime: Okay so I've been meditating for a really really long time and then I became a disciple. The reason why I found Joe is because I'd injured my foot and he wrote a book called "You Are the Placebo" and I didn't want to have foot surgery. That's the thing it was for the problem-solution piece of it. I'd always meditated. I didn't even know his whole thing was about meditation. Natalie: How did you find him? Jaime: My best friend gave me the book. Because she had been following him for awhile. But I was just trying to solve whatever the heck that thing was. I didn't know how deep he goes into meditation about how your body can change itself. And so it makes sense with, You Are the Placebo, but I never linked meditation and that before which was really awesome. Because before I thought it was, "I am a crazy, business entrepreneur that needs to get everything out of her head and feel okay" because otherwise I might have anxiety or whatever the pieces are. That's why I'd meditated before. And then I found this thing and I was like, "Oh there's so much more to it than that!" Natalie: And they are self-guided aren't they? Which I like because It's quite hard to just sit and not have thoughts. In fact, it's near impossible. Even the monks after many decades of practice don't' do it super well but they are far better than us. And I think I'd like to be like walking down the beach listening to meditation and then there you were, I was having a surf lesson and you were walking down the beach listening to a self-guided meditation. One where Joe got you to like ground your feet into the sand at one point, stop and just be. So I love the sound of that. Because I love walking and I like being active while meditating. What happens in that meditation? Jaime: So that one's really interesting. Joe has a bazillion different types of meditation. Some were shorter. This one's an hour and fifteen minutes. Some of our friends are like, "Oh surfing is so like that". It was funny when I was walking, thankfully eyes open for quite a bit, I was looking at some of the surfers and just thinking about how amazing that is too. There's a quite a few different pieces to his types of meditation. And so one is a big breathing aspect and then walking, where he doesn't have you do that because you look weird. But what he does as you start walking, he has you start envisioning your future and then walking as your future self. And imagining whatever happened that you want to have happened in the future as if it was a memory of the past. So you are walking and he is like talking about how to think of this and think of that, and as you are walking you feel amazing, on top of the world type of person. And then he has you stop and just close your eyes and imagine the feelings that you would feel: gratitude, joy - whatever those things are or affirmations are. And literally, because your body's been walking and energized, already like to me it goes like crazy. It makes you really feel the emotions. And then you walk again. And it levels up the emotional side of it. Levels up the feeling of, "Oh my gosh! This is what I'll feel like in the future." Right, that confidence, whatever those pieces are. And so you are sort of stepping into what that is and it makes a lot more believable. So as an entrepreneur I feel like, "Oh I want to speak on a stage at TEDx in front of a thousand people." I was chatting with somebody when I spoke in the Philippines, she's like, "I love crowds of 10,000 to 15,000 people." And I was like, "Hmmmm. I haven't done that before. 10,000 people that's a lot of people. Wow, Okay great!" She said, "The energy is just insane." And so then I started going, "Let's imagine what that would look like. I'm sure I can do it". And so in the walking meditation, I started bringing in some of those pieces. So when you start bringing in the pieces as if it already happened, especially the science behind meditation, it actually does. Have you heard the piano player thing? They had a study where: Some people actually play the piano in a certain number of hours per day for a specific song. Another one just did the finger exercises with no piano. And then the other ones meditated on it. So the people would actually meditate on it. They never touched the piano, and they actually were just as good as the other people. Natalie: When they finally went to play the piano? Jaime: Yes which is insane. Natalie: I've heard a few studies around stuff just re-visioning exercise on that. Jaime: Yes. It gets your body in certain state. It's really interesting to see the studies because we are placebos by the way, right? So we affect our thoughts and everything affects everything. And I think entrepreneurs need to get this better and better and better. It's not just clearing your brain it's all those thoughts that we think, that determine what we actually take action on, what we actually do. All those beliefs or whatever you want to say whether they are subconscious or not. When you start flushing those out, and you start imagining yourself..... I've had a friend who hated speaking and then he did like a hundred different speaking gigs all in a row just to get over the fear and to get really good at it. Well, you do a 100 of them and you'll get really good at it! Imagine meditating on it a hundred days in a row instead of actually having to go do it. And again there might be a little bit of twinge when you do the first one but it's going to feel so much more natural even just the visualization of it. And I've interviewed a ton of millionaires, 400 and something millionaires, so many of them bring up visioning, it's insane. I was not woo-woo at all and I started going down this road and interviewing millionaires and I'm like, "How come everybody keeps talking about this?". Because I really wanted to know and so then I started looking at the science behind it all. And then I'm like, "There's something to this", because I am a sciency kind of gal and then I've started implementing and doing it. It has literally changed so many things and what I can see is possible moving forward. Natalie: You mentioned that it's helped you, one being all grounded and not even noticed that visibly in you. You said your skin is glowing. You think you looked younger like not aging. What are some of the other benefits? Jaime: There's a whole thing on epigenetics which if you read any of Joe's books. Sleep Smarter by Shawn Stevenson talks about epigenetics - our bodies and what we feel basically. Because this is the thing, I don't think people really understand, and again the science is very very new behind all this. It hasn't really come out to the general population. If I say epigenetics, people are more like, "I don't have a clue what that is". But your DNA actually can turn on and off based on your environment. And so it's not all like you were born like this and now we are like that forever, it's what you ingest, what you are doing, what you are thinking that all affects your body, which makes logical sense when you think about it. We are not emotionless robots. All the pieces and parts really make a difference. You've seen the president go from looking really really young beforehand and how the heck did he age so much in such a short period of time? Like the stress and everything. And so it really affects your body. So you can do it in the opposite direction also. How can we change that? Natalie: I was telling you about Josh's friend Rohan, his father from England who's been doing transcendental meditation for something like forty five years or more. I haven't met him and I really want to meet him. I told you that right? Because he is late 70s and he looks like he is in his 40s. He gets up at five a.m every morning. He does one to two hours of transcendental meditation with the music and all the vibrations and everything. And he is apparently just super focused and onto it. He doesn't need much sleep. Just incredibly aware and has energy all day and that youth, that vitality and that absolute solidness around what he does and who he is. He's absolutely precise and clear on who he is and what energy he gives off. So that fascinates me. It does make me feel, yes you could change your state and you can change your entire DNA makeup. By the way, did you know that when you get sunburnt you are changing the DNA? There's a whole science behind it which you'd love. When you get sunburnt, your cells are exploding and we have billions of cells right, but they are exploding and each little explosion is shifting and changing your DNA. So overtime you can actually change your DNA of your body. Jaime: Good way or bad way? Natalie: I don't think sunburn is obviously good for you at all, but it's just more the point that scientists have seen that you are actually changing your DNA through that. So there must be other ways of changing your DNA. Jaime: When you look up epigenetics and you'll see some of those pieces because it's insane to read some of the studies on this. I didn't realize this. I'm like, "Man!". It is one of those things where it's such a new science so it seems a little woo-woo to people. It is with any sort of newer science. Natalie: I know scientists needs the data and the facts but also I just want to see it's working. Jaime: This is what I do, I'm like, "Well I'll test it and If I like it, I'll keep doing it and if I don't like it, then I won't." But there's a lot of Charletons that are like, "Oh you do this thing and it's amazing!". So that's what we have to be careful of, but to me I'll test anything and if I like it and I see results then I'll continue. I care about the smarts and logic. And so meditation has allowed me to tap in way more and not just be a 'running around like trying to do everything head wise', but actually tapping into all parts of your body. I never thought that your gut or intuition was a big deal until, again I heard so many millionaires going, "I went with my gut" and I'm like, "Wait! There's no real science behind that." I'll put a spreadsheet together so I can look at all the facts, this is why I am so science based because I need something to make a decision. I would almost never go with my gut. Natalie: Gut every time. Jaime: See... but to me I didn't get the point of gut. I thought that that wasn't logic. When you read like the book, Blank and we realize how amazing we are as human beings. We can make an assessment on something without even necessarily knowing the facts and data. Like that book was very eye opening to me because I was like, "Oh, maybe I do know more than logic will tell me and research and data." And so realizing that, along with everything else tapping into that. You can shut yourself off big time. Most people do. Most of the clients that I talk to I ask "What's your gut saying?" They are like "I don't know." Natalie: Oh really? I do it all the time. The only time that I haven't sometimes is travelling, because I listen to my gut and instinct all the time in travelling. "Don't go down there" or actually "Don't take that bus". Jaime: What does that feel like? Where? How do you do that? Natalie: Literally like a strong sensation to not go ahead and buy that ticket. Where? It's a good point. You do actually feel it in your stomach and then I feel like it just triggers straight away to your brain with a no. I have voice in my head going, "That's not a wise idea." It's really crazy and I just listen to it all the time. Jaime: I had heard this one place, and I have not verified sources but, what's interesting is they were saying that it's actually your heart that is making a lot of these decisions, and then going to either your stomach and then your brain and so it triggers all of them right? We sometimes think it's our brain first. Natalie: It's literally like a decision and sometimes your body will stop. Sometimes your body will stop walking like 'you are not going to go down there, Natalie'. It's the fight-or-flight response that I feel kicks in and that is triggered by your immune system and/or your nervous system, so I guess your heart is the thing that's beating. Jaime: We just don't know very much about our bodies though. Like it's kind of sad. I am trying to teach my children like, "Okay. Where do you feel that in your body?" so that they can become more in tune because I never was. I was like, what is that feeling? I would never go with my gut in general. So knowing and being able to say, "This actually works." I needed all the data from all the millionaires like, "Wait, you've went with your gut and that worked? Wow! Interesting." It would be really interesting to ask which ones typically go with their gut and which ones don't. Natalie: And where do you feel that in your body - that's an interesting question to ask anybody. Going on a bit of tangent here but asking 'how do you feel' and see what people's responses are, because if you ask a very pragmatic logic based person, they will go, "I am blah blah blah." Jaime: Okay so this is my best friend, she had to ask me every single day. She goes, "How do you feel?" and I'd say, "Good" and she'd go, "Good is not a feeling." "Great! I feel great!", she said, "That's not a feeling." I didn't have the words to express it. I literally had one of those little cards that said all the emotions on it. But I couldn't find the nuances between the emotions because I didn't think it was a big deal. Like what does it matter? Natalie: And it does matter. Jaime: It totally does now I know. I am teaching my children this. So tapping into intuition or tapping into your gut is an example. I don't know what that felt like. I was like, "Huh! Nope. I got nothing." The little nuances in anxiety or the little nuances in joy, the little nuances in things that I just never paid attention to. And yet we can be so much more expressive as human beings if you actually know that. I had beforehand thought, "If I just negate all the bad emotions and only felt the good ones, I'll be happy in my world". I mean you know in entrepreneurship too, it doesn't work that way. Shit happens. Natalie: It's a rollercoaster. Jaime: Exactly. You have to mitigate all of it and sometimes the crappy stuff is teaching you the most and you have to be okay with those emotions because if you try and negate that you won't take the risks, even calculated risks. You just won't make the steps towards that because you are so scared of negative emotions. It's an interesting thing. Natalie: I think a lot of people live in the state of, "I'm okay. I'm okay. So I am not going to show any emotions." And you asking me the other day, "Do you feel that you tapped into that? Are you emotional?" I have my moments around my Dad because I was quite surprised that I wasn't more upset or just really in that state, but I do think it's because I focused on celebrating his life. It doesn't mean I think I shut down my feelings. Like I will have my moments where I'll just cry. As I told you I am big soak in movies. I'll just have waterworks in movies. I feel like a lot around animals and nature. I don't worry so much or sweat the small stuff but I often think about global issues or environment or inhumane treatment of animals or people. And that stuff gets me really emotional but I think there are so many people who are walking through life they are taking the drugs and numbing them. Jaime: But that's the point right? The placebo, the book is all about, you don't need to rely on what we think. One of the reasons why we take a placebo and think it will work is because people have told us that it will work. If a doctor someone of high authority goes, "This will work for you." Even if it numbs you like crazy, you are like, "Oh then half of it's probably the placebo effect and the pills don't even work." So it's one of those things where us knowing ourselves better. If you are the type, "I am emotional in these sort of ways and I don't need to like make myself be emotional in other ways either", but knowing yourself better makes a huge difference. So if you do get sick or whatever, trying to pay attention to what those emotions were within it and then solving that instead of going after like, "I just need more alcohol" or "I need more drugs". Like when I injured my neck they gave me Hydrocodone and I'm like, "That's a lot!". It's a narcotic. They gave me a lot of pills. I was kind of surprised. They gave me like three sets of pills. Natalie: The United States scares me with what they give out. It's such a pill based society. Jaime: And I was like, "So how do I fix it though?". It's one thing to numb the pain and I am okay with pain I can handle a lot of pain but how do I fix it? Nobody really went down that path which sucks. Natalie: It does. Western medicine is very much like immediate solution where as I love the Eastern philosophy around preventing it before it's even happened. Jaime: Yes but the thing is I agree a thousand percent but because we've already gone past the point. So again this is western world but we are sold that we can have everything right now and this is why meditation is so important too. Because we are moving at a constant pace especially entrepreneurs. We are problem solvers and we wanted the problem solved yesterday not today. And so a pill, sure! Faster, easier, more efficient. Natalie: The headache was just from the hours of pampering and all the detox. And when I was in that yoga class, that restorative yoga which I loved and I was having trouble with the hamstring pose and it was really like sinking in. Sinking into that pose and feeling the pain and I wanted to come out of it because we had to hold it for five minutes. And that's when she said, "If you are challenged by this pose, you probably have issues with control, because the control that you put into your everyday life will manifest itself into your basically your hamstring." So the tightening there is the constant control or tension. And I think in intrinsically you know that but whatever we are holding any source of tension or pain or even love manifests itself in your body. Jaime: So that's the whole point of Joe Dispenza, the whole point completely. He was a doctor and he actually cut his spinal cord. It was like crazy he couldn't walk and he didn't want to have surgery. And all the doctors are like, "So you kind to have surgery to fix this", and he was, "I am not going to do it." He meditated. And people were like, "Okay, you meditated your spinal healing. That's a little insane." Natalie: Have he done meditation before? Jaime: I don't remember. I think he must have done something. I'm pretty sure he wouldn't be like, "Oh I am going to try meditation and see if this works." He was a chiropractor so he knew the body really really well but what is interesting like you were saying is being able to have whatever is existing in our body usually is for a reason. And unfortunately because we are problem solvers and we want to fix this so fast we just take the pill and go, "That will be okay." But more and more instances of cancer, more and more instances of crazy stuff and we are going, "What's wrong?". Well yeah it's probably food and stuff like that too but there's so many things that we don't understand that us taking care of ourselves, like you said the eastern side of things could have probably prevented but now we are at this tipping point where we can't see the force for the trees anymore. And so that's why it's great that he wrote the book called, You Are the Placebo because there's literally everybody going, "I have a problem. I need a solution." And so being able to show people, "Oh by the way, this could help this." Natalie: I was going to say it sounds of ironic but I am about to say we have to take control or more importantly, we have to take responsibility because things are not going to get better. We are going to have more and more technology. We'd be more and more connected. We are going to have more and more devices. We are going to have more multi-tasking. We are going to have more and more things in our life that are causing us to live lives in totally different way where we don't have peace, quiet, nature, reflection, timeout, thinking time, quiet time. And so we just have to and that's why I am so proud of you because you are making time because you love it every morning to do your meditation. Jaime: One I didn't love it. I couldn't sit for five minutes. I used to lay down because I couldn't sit up. So I couldn't sit up for that long and I hated the five minutes every single time. It's just very much an evolutionary process. That being said I learned my own process. A lot of clients are resistant because they are entrepreneurs and logical and my brain is way too crazy, "I can't do it Jaime". I was like, "I have the same crazy brain you do. I have ADD literally". And so when we are looking at, "Okay what can you do as a first step?" We talked about five minutes of headspace. Headspace is great, Calm app is great, just to sort of slowly get into that and then I have people come back and they are like, "Oh that felt a little better." And then what is that next step and what is that next step, I did this as part of the evolutionary process it to try to make meditation efficient. I would get all the crap out of my head so that way I could feel like i could be more clear. David Allen's Getting Things Done, getting everything out of your head. So I would do that piece along with having this inspired thoughts of, "Oh you know what I should do and this". Natalie: You'd actually literally go sit down or lie down to meditate but then you'd have bing bing bing thoughts. So you'd actually then stop the meditation? Jaime: I wouldn't actually stop the meditation. It's really kind of funny I had a eye pillow on and I'd literally have a journal right next to me and I'd scribble. It's just like a twenty, thirty minute meditation, it wasn't a lot because I would only do the first piece like this. I would literally just go, "Oh!" and write those. Changes of launch plans or the ideas that I have. And then I would be able to clear and be a lot better. So it's still guided meditation but this is what I have my clients do because in general they are like," I can't make it stop." You know what makes it stop? Write all that crap down. And because David Allen talks about with getting things done, if it's still on your head it will keep reminding it. It will keep bringing it up. So there you have it. This topic of Personal Freedom here on the Quest for Freedom Podcast continues to come back to freedom of the mind in so many respects. I know I will continue to delve deeper into this. In the next episode I'll be discussing personal freedom from a place of less stuff weighing you down - as in decluttering. Tune in for that one. And read the full show notes for this episode at nataliesisson.com/7 You can also sign up to get fresh, hip and timely email updates when I release a new episode. Or you can simply subscribe in iTunes, Stitcher, SoundCloud or Google Play and make my day - and hopefully make yours.   See acast.com/privacy for privacy and opt-out information.

In this episode of late night family values Aaron and Leslie cut to the heart of darkness by getting real with local stand up comedian Samuel John Poulter. We learn how a person spirals from mental illness to drug addiction to attempted suicide! We also learn how not to extract Hydrocodone, and what it means […] The post FAMILY VALUES 004: “Bring Us Your Mentally Ill, Your Addicted & Your Suicidal!” appeared first on Utah Podcast Network.

Acetaminophen. Ibuprofen. Hydrocodone. Ketorolac. Morphine. Hydromorphone. Oral Acetaminophen (Tylenol) Give every 4-6 hours Regular strength – 325mg Extra strength – 500mg Maximum Daily Dose – 3000mg Oral Ibuprofen (Advil) NSAID Give every 4-6 hours Regular strength – 200mg Therapeutic Ceiling – 400mg Oral Hydrocodone-Acetaminophen (Vicodin, Norco) Give ever 4-6 hours Common doses – 5-325mg, 7.5-325mg, […]

Generic Name hydrocodone/acetaminophen Trade Name Norco Indication management of moderate to severe pain Action alters the perception and reaction to pain by binding to opiate receptors in the CNS, also suppresses the cough reflex Therapeutic Class opioid Analgesic, allergy, cold… The post Hydrocodone-acetaminophen: Norco (opioid Analgesic, allergy, cold and cough remedies, antitussive) appeared first on NURSING.com.

More on controlled substances. Today we discuss Hydrocodone, an opioid.

Episode 6 of In Plain Cite answers a question from our Criminal Just Act panel.  Lex and Rachel review some of the more important United States Sentencing Guideline amendments that went into effect on November 1, 2015.  The discussion includes changes to the guidelines dealing with Hydrocodone, the Mitigating Role Adjustment, Inflationary Adjustments, Economic Loss, and the Single Sentence Rule.

Are you on an Opioid drug such as Percocet, Vicodin, Hydrocodone, etc for chronic pain?  Do you have chronic knee pain, chronic low back pain, etc.?  Do you know your options beside drugs and surgery?  Educating yourself could save your life. www.johnbartemus.comwww.functionalmedicinecharlotte.comwww.functionalmedicinedoctors.comwww.youtube.com/acceleratechirowww.facebook.com/functionalmedicinecharlottewww.twitter.com/functionmediclt

Hydrocodone Painkillers Last month, the Drug Enforcement Administration changed its classification of hydrocodone containing pain relievers. The new rules will make it more difficult for some patients to get their medications. What will they mean for you? Movember By now, everyone is pretty well aware that October is colored pink to draw attention to breast […]

Vicodin Withdrawal and Detox is the subject of this Special Report by Alex Castillo, a mental health counselor and substance abuse specialist. What is Vicodin? Vicodin contains a combination of acetaminophen and hydrocodone. Hydrocodone is in a group of drugs called opioid pain relievers. An opioid is sometimes called a narcotic, and acetaminophen is a less potent pain reliever that increases the effects of hydrocodone. Vicodin is used to relieve moderate to severe pain. What is Vicodin withdrawal? Vicodin addiction is typically fueled by the constant need to get more of the drug to prevent the user from going into withdrawal. Vicodin withdrawal occurs because the individual, whether it is someone who is legitimately prescribed the medication or someone who is abusing illicitly, develops a physical and mental dependence on the drug over time. When they stop using Vicodin, they begin to experience the uncomfortable and painful response that the body goes through as the result. They will have strong cravings for Vicodin, and the withdrawal symptoms can be very similar to those experienced in heroin withdrawal. What are withdrawal symptoms of Vicodin? Anxiety, diarrhea, hot or cold flashes, kicking movements, loss of appetite, nasal discharge, nausea, severe backache, sneezing, twitching, muscle spasms, vomiting and weakness. What is Vicodin detox? Treatment for Vicodin addiction is similar to treatment for other opioid addictions. Admissions to a medically supervised detox clinic will help the user to manage the worst of negative withdrawal symptoms. In order to minimize the effects, it is recommended to gradually reduce the use of Vicodin with the help of a healthcare professional.       Click Here to Download a PDF version of this report.         Do you have more questions about drug abuse and addiction? Call our Toll-Free Recovery Hotline at 1-800-839-1682 and discover the best treatment options for you. Our experienced counselors are available 24 hours a day to take your call and get you the help or information you need. Our drug rehab center offers a unique and affordable holistic approach to addiction treatment. Our holistic addiction and treatment program has helped addicts from all over the United States, Europe and Canada overcome their substance addictions and achieve long term recovery. We treat the individual's specific needs, including working with families.   Find the Original Post with Downloadable Podcast and Drug Abuse Fact Sheet Here: Vicodin Withdrawal and Vicodin Detox

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