Commune in Grand Est, France
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MINNESOTA — In this episode of the Echo Press News Minute, reporter Lisa Johnson talks about the hidden gems of Minnesota Lake Country, the family chosen as this year's Relay for Life honorees, the Summer Sounds concert series and a local non-profit stepping in to help in the wake of a tragedy. Those stories and more, this week on the Echo Press News Minute. Check out the top headlines from July 9 and July 11, 2025,below: July 9, 2025 Ringing in 2025 Fourth of July with a little bit of the past Looking for something to see or do? Here are 7 'hidden gems' around Minnesota lakes country Hartmann, Caruthers, Kohler named as Alumni Hall of Fame 2025 inductees Rost/Gran family from Hoffman and Villard chosen as this year's Relay for Life honorees Merten brothers, Larry Lund to be inducted into Viking Speedway Hall of Fame July 11, 2025 Briefs must be filed by July 24 in Alexandria stabbing death case Third annual Summer Sounds by Brophy kicks off July 15 An Alexandria non-profit steps up to help a grieving sheriff's office Disney's 'Moana Jr.' takes to the Andria Theatre stage Golf: Lisa Grimes, David Kjos selected as honorees for 104th Resorters Tournament Opinion
In this first installment of our four-part conversation with 1993 U.S. Women's Open Champion Lauri Merten, we journey back to where it all began. A self-proclaimed “cheesehead” born in Waukesha, Wisconsin, Lauri shares her early memories of snowy winters, fried cheese curds, and a childhood move to Arizona that would unknowingly set her on the path to major championship glory.Lauri opens up about a childhood shaped not by early athletic success, but by determination, resilience, and a tight-knit family. With heartfelt humor and humility, she recalls her initial forays into sports — including a memorable knee injury during a failed long jump attempt — and how golf became her sanctuary. A set of hand-me-down Patty Berg clubs and a desire to spend time with her father sparked a love for the game that would carry her to the top of women's golf.Listeners will hear about the summer golf school that transformed Lauri's outlook, the strict (but loving) influence of her father, and how her shorter left leg created challenges — and ultimately forged a gritty, repeatable game that made her the “Trash Queen” on tour, getting up-and-down from everywhere.Lauri's authenticity shines as she reflects on meeting Bob and Dolores Hope, playing in celebrity pro-ams, and the powerful women who helped pave her way in the game. Her voice adds an intimate touch to a story that is both deeply personal and inspiring.Join us as we uncover the roots of a U.S. Open champion — a story that's as much about heart and perseverance as it is about fairways and greens.Give Bruce & Mike some feedback via Text.Support the showFollow our show and/or leave a review/rating on: Our Website https://www.forethegoodofthegame.com/reviews/new/ Apple Podcasts https://podcasts.apple.com/us/podcast/fore-the-good-of-the-game/id1562581853 Spotify Podcasts https://open.spotify.com/show/0XSuVGjwQg6bm78COkIhZO?si=b4c9d47ea8b24b2d About "FORE the Good of the Game” is a golf podcast featuring interviews with World Golf Hall of Fame members, winners of major championships and other people of influence in and around the game of golf. Highlighting the positive aspects of the game, we aim to create and provide an engaging and timeless repository of content that listeners can enjoy now and forever. Co-hosted by PGA Tour star Bruce Devlin, our podcast focuses on telling their life stories, in their voices. Join Bruce and Mike Gonzalez “FORE the Good of the Game.” Thanks so much for listening!
In Part 2 of our four-part conversation with 1993 U.S. Women's Open Champion Lauri Merten, we explore the winding and often challenging road that led her to the LPGA Tour—and her breakthrough victory.Lauri shares her early experiences playing in professional events as a teenager, including a memorable LPGA event at Sun City with her father on the bag and her stunning 67 that made her an overnight leader. From those formative moments, we follow her journey through Q-School heartbreak, international pro-ams in Japan, and the financial support that made chasing her dream possible.Lauri opens up about the pressure-packed nature of LPGA qualifying and the unlikely first win that came in 1983 at the Rail Charity Classic in Springfield, Illinois—where advice from her father, an eagle on 13, and a prayerful putting green moment all played a part in her emotional triumph. She also recounts her second LPGA win in 1984 at the inaugural Jamie Farr Toledo Classic, where she outdueled none other than Nancy Lopez on the final day—on her birthday, no less!With vivid stories involving Pat Bradley, Charles Barkley, and iconic tour stops, Lauri gives listeners a candid and heartfelt look at life on the LPGA Tour during its golden era. Her humor, humility, and competitive fire shine through as she reflects on the people and places that shaped her career.Join us for this inspiring episode as Lauri Merten continues her journey FORE the Good of the Game—sharing stories, wisdom, and memories that golf fans of all generations will treasure.Give Bruce & Mike some feedback via Text.Support the showFollow our show and/or leave a review/rating on: Our Website https://www.forethegoodofthegame.com/reviews/new/ Apple Podcasts https://podcasts.apple.com/us/podcast/fore-the-good-of-the-game/id1562581853 Spotify Podcasts https://open.spotify.com/show/0XSuVGjwQg6bm78COkIhZO?si=b4c9d47ea8b24b2d About "FORE the Good of the Game” is a golf podcast featuring interviews with World Golf Hall of Fame members, winners of major championships and other people of influence in and around the game of golf. Highlighting the positive aspects of the game, we aim to create and provide an engaging and timeless repository of content that listeners can enjoy now and forever. Co-hosted by PGA Tour star Bruce Devlin, our podcast focuses on telling their life stories, in their voices. Join Bruce and Mike Gonzalez “FORE the Good of the Game.” Thanks so much for listening!
In this third installment of our four-part conversation with 1993 U.S. Women's Open Champion Lauri Merten, we dive headfirst into the emotional and unforgettable week at Crooked Stick that changed her life forever. With raw honesty and captivating detail, Lauri takes us through the rollercoaster of self-doubt, resilience, and unlikely triumph that defined her historic victory.Coming off a missed cut the week prior and wrestling with confidence issues, Lauri describes how a simple shopping trip and a bronze sculpture became her quiet source of inspiration heading into the championship. From early nerves and pep talks from her caddie, Tom Hanson, to clutch birdies and gritty par saves, she walks us through each turning point with vivid recollections—including a dramatic chip-in, a critical bogey save on 11, and her birdie at 16 that sent goosebumps through the gallery.You'll hear how Lauri navigated the pressure, a weather-delayed final round, and the tension of watching challengers like Donna Andrews and Helen Alfredsson fall just short. She reflects on her mindset, her putting drills that paid off at just the right moment, and the joy—and shock—of hearing the final roar when the final challenger's putt missed the mark.With her trademark humor and humility, Lauri also shares heartfelt moments about her parents, her mixed feelings about a controversial Sports Illustrated article, and her plans to finally share some cherished memorabilia with the USGA.This episode is a tribute to perseverance, belief, and the magic that can unfold when preparation meets opportunity. Don't miss Lauri's inside story of one of the most inspiring and underdog victories in U.S. Women's Open history.Give Bruce & Mike some feedback via Text.Support the showFollow our show and/or leave a review/rating on: Our Website https://www.forethegoodofthegame.com/reviews/new/ Apple Podcasts https://podcasts.apple.com/us/podcast/fore-the-good-of-the-game/id1562581853 Spotify Podcasts https://open.spotify.com/show/0XSuVGjwQg6bm78COkIhZO?si=b4c9d47ea8b24b2d About "FORE the Good of the Game” is a golf podcast featuring interviews with World Golf Hall of Fame members, winners of major championships and other people of influence in and around the game of golf. Highlighting the positive aspects of the game, we aim to create and provide an engaging and timeless repository of content that listeners can enjoy now and forever. Co-hosted by PGA Tour star Bruce Devlin, our podcast focuses on telling their life stories, in their voices. Join Bruce and Mike Gonzalez “FORE the Good of the Game.” Thanks so much for listening!
In the heartfelt conclusion of our four-part conversation with 1993 U.S. Women's Open champion Lauri Merten, we explore life beyond the ropes and the journey that followed her greatest triumph. With sincerity and introspection, Lauri opens up about the challenges of balancing fame, personal relationships, and the emotional toll of a life in competitive golf.She reflects on the impact of her U.S. Open win—from newfound celebrity to the struggles of maintaining her game and marriage. Lauri shares stories of teeing it up with legends like Jack Nicklaus and Greg Norman, and the unexpected honor of flying on Jack's private plane after a memorable Three Tour Challenge. She also discusses stepping away from the game at her peak and her transition into a quieter, more creative life as a gardener and decorative painter.We also hear about her emotional return for the inaugural U.S. Senior Women's Open—dusting off old clubs, finding places to practice, and rediscovering her swing two decades later. Through highs and lows, her enduring love for the game and her authenticity shine through.As we close, Lauri answers our signature final three questions with honesty and grace, sharing what she might have done differently, where she'd take a career mulligan, and how she hopes to be remembered—not just as a major champion, but as someone who cared deeply for others and stayed true to herself.This episode is a powerful reminder that the stories behind the trophies are often the most inspiring of all.
In dieser Folge tauchen wir tief in die Welt des inneren Kindes ein – jener verletzlichen, kreativen und oft überhörten Stimme in uns. Unsere Gästin, Michaela Marten, ist Expertin für innere Kindarbeit und teilt mit uns, warum der Zugang zu unseren frühen Prägungen so essenziell für persönliches Wachstum ist. Gemeinsam erkunden wir, wie ungelöste Kindheitsmuster unser heutiges Leben beeinflussen und wie wir lernen können, diese sanft zu heilen. Michaela gibt wertvolle Impulse, wie wir unser inneres Kind erkennen und liebevoll in unser Erwachsenenleben integrieren können. Sie erklärt, warum bewusste Selbstfürsorge und emotionale Heilung untrennbar miteinander verbunden sind. Anhand praktischer Übungen zeigt sie Wege auf, um alte Verletzungen loszulassen und wieder mehr Leichtigkeit, Vertrauen und Freude ins Leben zu bringen. Ob du gerade erst von innerer Kindarbeit gehört hast oder schon tiefer in das Thema eingetaucht bist – diese Folge hält wertvolle Erkenntnisse für dich bereit. Freue dich auf eine inspirierende Reise zu deinem inneren Kind und erfahre, wie du mit ihm in einen heilsamen Dialog treten kannst. Instagram: https://www.instagram.com/michaela_merten/ Website: https://michaela-merten.de/ Happiness House (Academy und Community): https://happiness-house.de/ Podcast: https://open.spotify.com/show/1BI5lIhdJ2FlRsmQ1HPOrp?si=dugqiL0zSeOwRrXGN3-Dtg&utm ************* Zu meinem Coaching: Mail an aw@annelinawaller.com Blog: http://annelinawaller.com Podcast: https://open.spotify.com/show/58BYIK2fH9d9ho2Oqx3wLI?si=jDBCCLiwTTyEupCln0oL6 Instagram: https://www.instagram.com/annelinawaller/ Pinterest: https://nl.pinterest.com/annelinawaller/ Buch: https://www.ventil-verlag.de/titel/1935/ein-bauch-voll-gluck
Daniel catches up with Rick Merten, Managing Director of InsideOut Group, a strategy-led B2B marketing consultancy with a unique approach - embedding fractional marketers inside businesses to drive growth from within. Originally founded in 2001 as an early digital start-up called Permission, InsideOut Group has evolved into a powerhouse for businesses looking to scale effectively. Daniel and Rick discuss how to position your business in the minds of customers, the power of scaling through niching, and how to embed your values within your team - even in a remote work environment.
In dieser Episode deckt Cordelia gemeinsam mit der renommierten Ernährungswissenschaftlerin, Podcasterin und Buchautorin Laura Merten populäre Ernährungsmythen auf. Dabei räumen die beiden mit weit verbreiteten Fehlinformationen auf und liefern wissenschaftlich fundierte Fakten. Laura hostet den Podcast "Satte Sache | Ernährung & Wissenschaft”, in dem sie Themen rund um gesunde Ernährung, Hormone, Verdauungsprobleme und vieles mehr behandelt. Viele weitere Mythen busten die beiden morgen dort in Lauras Podcast.
Alles nur gefaked? Über Vortäuschung und Manipulation bei psychischen Beschwerden In dieser kontroversen Folge widmen sich Andreas und Werner einem heiklen, aber wichtigen Thema in der psychologischen Praxis: Der bewussten oder unbewussten Verzerrung von Krankheitssymptomen. Wie lässt sich zwischen echtem Leiden und übertriebener Darstellung unterscheiden? Wann werden Beschwerden heruntergespielt, wann überbetont? Die beiden Hosts beleuchten die verschiedenen Facetten dieses komplexen Phänomens - von der Simulation nicht vorhandener Symptome bis hin zur Bagatellisierung ernsthafter Probleme. Sie diskutieren, warum Menschen ihre Beschwerden manchmal verzerrt darstellen und welche Beweggründe dahinterstecken können. Dabei wird deutlich: Nicht jede Übertreibung ist bewusste Täuschung, und nicht jedes Herunterspielen ist mangelnde Krankheitseinsicht. Besonders spannend wird es, wenn die beiden ihre praktischen Erfahrungen teilen: Welche diagnostischen Instrumente und Beobachtungsmethoden helfen bei der Einschätzung? Wie können Diskrepanzen im Verhalten erkannt werden? Und welche Rolle spielen standardisierte Beschwerdevalidierungstests? Eine aufschlussreiche Episode für Fachleute und Interessierte, die zeigt, wie komplex die Unterscheidung zwischen authentischen und verzerrten Symptomdarstellungen sein kann - und warum eine sorgfältige Diagnostik so wichtig ist. Links: Begriffsdefinition https://dorsch.hogrefe.com/stichwort/beschwerdenvalidierung Leitlinie Begutachtung bei psychischen und psychosomatischen Störungen https://register.awmf.org/de/leitlinien/detail/051-029 Überblicksartikel Beschwerdevalidierungsverfahren (eher unkritisch) Merten, T. (2020). Beschwerdenvalidierung in der psychologischen und medizinischen Begutachtung. Praxis der Rechtspsychologie, 30(2), 59-76. https://sozialrecht-bdp.de/wp-content/uploads/Beschwerdenvalidierung.pdf Artikel (kritisch über Beschwerdevalidierungsverfahren) Nübling, R., Henn, J., Kaiser, U., Schmidt, J. & Bassler, M. (2020). Zur Validität subjektiver Patientenangaben: Anmerkungen zur Beschwerdenvalidierung. Zeitschrift für Psychiatrie, Psychologie und Psychotherapie, 68(2), 81–95. https://tinyurl.com/3354yb45 Wertz, M., Mader, E., Nedopil, N., Schiltz, K. & Yundina, E. (2020). Antwortverzerrung oder Symptombelastung? Beschwerdeschilderung von psychiatrischen Patienten und sozialmedizinischen Begutachtungsprobanden. Der Nervenarzt, (92), 1163–1171. https://tinyurl.com/54akr55u Kirchhoff, L. & Steinert, T. (2019). Klassifikationsgüte der Beschwerdevalidierungstests Word Memory Test und Strukturierter Fragebogen Simulierter Symptome. Der Nervenarzt, 90(5), 516–522. https://tinyurl.com/bd9c9ndr Soziale Erwünschtheit, Beispiel eines Instruments: https://tinyurl.com/yzrafem9
When I was doing my undergraduate degree back in the 90s, the Internet was a bit of a novelty. It was fun to play with, and you could see theoretically how it was probably going to be quite important. I'm not sure I would have predicted how completely it now pervades every area of human life, though: work, civil society, leisure and social interactions. There's still, however, a significant digital divide. Not everyone has easy access, or any access to the internet, and its systemic importance in all of these areas means this is more of a disadvantage than it's ever been. Merten Reglitz, Associate Professor of Philosophy at the University of Birmingham, thinks it's time we recognised internet access not just as a significant good, but as a human right. Here is Merten's recently published book on the topic, an overview of it and an article that sets out the book's main defence of the idea of a new right.An article and another article opposing the idea that internet is a human right.The latest figures on global connectivity from the ITU.Freedom House's ‘Freedom of the Net' reports on internet freedom.Ethics Untangled is produced by IDEA, The Ethics Centre at the University of Leeds.Twitter/X: @EthicsUntangledBluesky: @ethicsuntangled.bsky.socialFacebook: https://www.facebook.com/ideacetlLinkedIn: https://www.linkedin.com/company/idea-ethics-centre/
Soziale Medien aus linguistischer Sicht: Muster Was sind Soziale Medien? Soziale Medien als Massenmedien? Algorithmen, Streams und Netzwerke: technische Infrastruktur und Subversion Metapragmatische Perspektive: Thematisierung von Hate, Körperakzeptanz Sprachliches Handeln statt Informationsübertragung: Vergemeinschaftung Forschungspraktische Probleme Was sind Konstruktionen? Konstruktionsgrammatik Registerwissen und Sprachkompetenz Emojis Multimodalität und Bildanalyse Digitale Gesellschaft und Deep Mediatization: Abhängigkeit, Sucht und Medienkompetenz Regulierung von Sozialen Medien und Aufklärung Ethische Aspekte der Soziale-Medien-Forschung Die Zukunft der Sozialen Medien
In dieser Episode ist Laura Merten, auch bekannt unter 'Satte Sache', zu Gast. Wir sprechen über die Bedeutung von Ballaststoffen für unsere Gesundheit, insbesondere in Bezug auf die Blutzuckerregulation und die Verdauung. Laura gibt praktische Tipps, wie man die Ballaststoffzufuhr schrittweise erhöhen kann, um Verdauungsprobleme zu vermeiden. Zudem gehen wir der Frage nach, wie Stress und Schlaf die Blutzuckerregulation beeinflussen und wie regelmäßige Mahlzeiten sowie achtsames Essen helfen können, Blutzuckerschwankungen zu reduzieren. Laura erklärt auch, ob Blutzuckersensoren wirklich nützlich sind oder unnötige Panik schüren, und warum gesundes Essen manchmal trotzdem zu Blutzuckerspitzen führen kann. Du erfährst wie hoch die optimale Ballaststoffzufuhr ist, wie du mit möglichen Nebenwirkungen umgehen kannst und welche Bedeutung Schlaf und Stressbewältigung für unser Wohlbefinden haben. Folge mir, [@fit__laura](https://www.instagram.com/fit__laura/), gerne auf Instagram, um tägliche Tipps, Motivation und Rezepte zu erhalten. Hast du Fragen oder Feedback zum Thema der Episode? Schreib mir gern! Kennst du schon meine [App](https://www.fitlaura.de/membership/)? Das All in One Paket für DEINE Gesundheit! Teste sie gerne für 1 Monat, jederzeit kündbar & dich erwarten wöchentlich neue Inhalte zu den Bereichen BODY MIND FOOD. Dort gibt es z.B. auch Workouts mit mir, Trainingspläne und Übungsanleitungen. Hier erfährst du mehr über Laura Merten: Website [sattesache.de](https://sattesache.de) [Ihr Podcast 'Satte Sache'](https://open.spotify.com/show/61827VaUiCsysUxdvi8kzO) Instagram [@sattesache](https://www.instagram.com/sattesache/?hl=de)
In dieser Episode ist Laura Merten, bekannt als Sattesache, zu Gast. Wir sprechen über die Bedeutung von Ballaststoffen für unsere Gesundheit, insbesondere in Bezug auf die Blutzuckerregulation und die Verdauung. Laura gibt praktische Tipps, wie man die Ballaststoffzufuhr schrittweise erhöhen kann, um Verdauungsprobleme zu vermeiden. Zudem gehen wir der Frage nach, wie Stress und Schlaf die Blutzuckerregulation beeinflussen und wie regelmäßige Mahlzeiten sowie achtsames Essen helfen können, Blutzuckerschwankungen zu reduzieren. Laura erklärt auch, ob Blutzuckersensoren wirklich nützlich sind oder unnötige Panik schüren, und warum gesundes Essen manchmal trotzdem zu Blutzuckerspitzen führen kann. Zuletzt beantworten wir ...Du möchtest deinen Podcast auch kostenlos hosten und damit Geld verdienen? Dann schaue auf www.kostenlos-hosten.de und informiere dich. Dort erhältst du alle Informationen zu unseren kostenlosen Podcast-Hosting-Angeboten. kostenlos-hosten.de ist ein Produkt der Podcastbude.Gern unterstützen wir dich bei deiner Podcast-Produktion.
When they launch a business, most founders don't have selling on the top of their mind. But when it comes time to consider the future – for themselves, the company, and employees – an ESOP (Employee Stock Ownership Plans) can be a win-win.“A lot of founders would say, ‘I'm not ready to sell the company.' But the beauty about the ESOP is that it can create a market for the sale of your shares … and you control the timing,” explains Bill Merten, a partner in Krieg DeVault's ESOP Practice. In breaking down that beauty with Krieg DeVault colleague and host George Lepeniotis, Bill outlines the flexibility and financial benefits of ESOPs versus traditional sale options like private equity or strategic buyers. He describes the unique advantages to employee beneficiaries as well as founders and details how an ESOP is structured and financed.Connect and Learn More☑️ Bill Merten | LinkedIn☑️ Krieg DeVault | LinkedIn | X | Facebook | Instagram☑️ George Lepeniotis | LinkedIn☑️ Krieg DeVault | LinkedIn | X | Facebook | Instagram☑️ Subscribe Apple Podcasts | Spotify | Amazon Music
Musik: Birgit Minichmayr: Kisi Kids " Ich bin nie mehr allein", "Glaubensbekenntnis", Helden sind Sterne der Geschichte" Heft: ein frohes Gotteskind- Das leben der seligen Sr. Blandine Merten, Kindern erzählt von M. Hermenegildis Visarius, Ursuline vom Calvarienberg; www.blandinenarchiv.de/kontakt
Heft: ein frohes Gotteskind- Das leben der seligen Sr. Blandine Merten, Kindern erzählt von M. Hermenegildis Visarius, Ursuline vom Calvarienberg; www.blandinenarchiv.de/kontakt
Welcome James Merten, United States Coast Guard sector Columbia River Marine Transportation Recovery Unit Coordinator and Columbia River Representative at federal, state, local, and industry levels.
Seine Freunde behaupten, er habe mehr Glück als Technik. Die Rede ist von Neu-Nationalspieler Nick Merten. Ob das wirklich stimmt, gehen die Schlägertypen in der aktuellen Folge auf den Grund. Gemeinsam plaudern sie über die bevorstehende Padel-Europameisterschaft wie bereiten sich die Jungs vor, und welche Ziele haben sie sich gesteckt? Ihr werdet zudem Einblicke in Nicks faszinierende Reise vom Tennisspieler zum Padel-Star bekommen und erfahren, wie mühelos er seine sportliche Karriere mit dem Studium an der Sporthochschule unter einen Hut bringt. Ganz nebenbei offenbart er seine nicht vorhandenen Kochfähigkeiten und wie sich Schiebedächer für Padelspieler anbieten. Unser Padel-Podcast Die Schlägertypen wird ...Du möchtest deinen Podcast auch kostenlos hosten und damit Geld verdienen? Dann schaue auf www.kostenlos-hosten.de und informiere dich. Dort erhältst du alle Informationen zu unseren kostenlosen Podcast-Hosting-Angeboten. kostenlos-hosten.de ist ein Produkt der Podcastbude.Gern unterstützen wir dich bei deiner Podcast-Produktion.
Drübergehalten – Der Ostfußballpodcast – meinsportpodcast.de
Seine Freunde behaupten, er habe mehr Glück als Technik. Die Rede ist von Neu-Nationalspieler Nick Merten. Ob das wirklich stimmt, gehen die Schlägertypen in der aktuellen Folge auf den Grund. Gemeinsam plaudern sie über die bevorstehende Padel-Europameisterschaft wie bereiten sich die Jungs vor, und welche Ziele haben sie sich gesteckt? Ihr werdet zudem Einblicke in Nicks faszinierende Reise vom Tennisspieler zum Padel-Star bekommen und erfahren, wie mühelos er seine sportliche Karriere mit dem Studium an der Sporthochschule unter einen Hut bringt. Ganz nebenbei offenbart er seine nicht vorhandenen Kochfähigkeiten und wie sich Schiebedächer für Padelspieler anbieten. Unser Padel-Podcast Die Schlägertypen wird ...Du möchtest deinen Podcast auch kostenlos hosten und damit Geld verdienen? Dann schaue auf www.kostenlos-hosten.de und informiere dich. Dort erhältst du alle Informationen zu unseren kostenlosen Podcast-Hosting-Angeboten. kostenlos-hosten.de ist ein Produkt der Podcastbude.Gern unterstützen wir dich bei deiner Podcast-Produktion.
Andrew Pollard, President and CEO of Blackrock Silver (TSX.V:BRC – OTCQX:BKRRF), joins us to outline the key focus of the 20,000 meter drill program starting up this month in July at its 100% controlled Tonopah West Project, located in the Walker Lane trend of Western Nevada. The Updated MRE at Tonopah West contains a total of 0.57 million ounces of gold and 47.74Mozs of silver or 100.04Mozs of silver equivalent. The key initiatives with this year's drill program is to put in approximately 50 drill holes to convert inferred resources to “measured and indicated” on their Merten and Bermuda veins, as well as to crystalize further expansion along the 1km vein corridor between the DPB, Victor, and NW Step-out areas. At present there are multiple deposits along 2.5kms of strike length and tracked across open vein corridor spanning 4km in strike length. One of the goals of this program is drill in between the large gaps (1.5km) remaining to infill these areas and bridge the deposits together as one larger deposit. The system also remains open to the south, northwest, at depth. We also discussion the various project derisking that their team is doing in the background like metallurgical testing and process flowsheet, hydrology studies, environmental studies, site infrastructure and the potential placement of a decline and processing mill, all in tandem with the exploration strategy. The company just raised $10Million in May, bringing in a larger stake from Eric Sprott, and is cashed up to do work beyond this drill program. If you have any follow up questions for Andrew regarding Blackrock Silver, then please email us at Fleck@kereport.com or Shad@kereport.com. For full disclosure, Shad is shareholder of Blackrock Silver at the time of this recording. Click here to visit the Blackrock Silver website to read over the recent news we discussed.
Nimm Kontakt mit mir auf. Ich freue mich über deine Impulse.In dieser Episode von "Business Beyond Mind" spricht Ilja mit Jana Merten, einer Psychologin, Hypnotherapeutin und Ausbilderin, die er 2022 bei einem Speaker Award kennengelernt hat. Diese Begegnung führte zu einem tiefgründigen Gespräch über die Herausforderungen und Transformationen innerhalb der psychotherapeutischen Praxis.Jana teilt offen ihre persönliche Reise und wie sie durch ihre eigene schwierige Kindheit geprägt wurde. Ihr Weg führte sie von einer von Pflichten dominierten Jugend, über die Auseinandersetzung mit ihrer Mutter, die Alkoholikerin war, bis hin zu ihrer eigenen Therapieerfahrung. Sie diskutiert die Rolle der Verletzlichkeit in der Therapie und wie wichtig es ist, sich als Therapeut authentisch und menschlich zu zeigen.Ein zentraler Punkt des Gesprächs ist Janas Kritik an der traditionellen Form der Psychotherapie, die oft als zu distanziert und formal empfunden wird. Sie betont die Notwendigkeit, dass Therapeuten ihre eigene Menschlichkeit und ihre eigenen Kämpfe anerkennen sollten, um eine echte Verbindung zu ihren Klienten herzustellen.Jana und Ilja tauchen auch in die Welt der Hypnotherapie ein, in der Jana eine tiefe Leidenschaft gefunden hat. Sie erklärt, wie Hypnotherapie tiefere emotionale Ebenen erreicht und effektiver sein kann als traditionelle Psychotherapie, besonders wenn es darum geht, lang eingefahrene emotionale Muster und Panzer zu durchbrechen.Diese Episode bietet Einblicke in die transformative Kraft der Hypnotherapie und die Bedeutung von Authentizität in der therapeutischen Arbeit. Es ist eine unverzichtbare Ressource für jeden, der sich für psychologische Transformation und persönliches Wachstum interessiert.Key Moments:Jana teilt ihre Kindheitserfahrungen und wie diese ihre Berufswahl beeinflusst haben.Diskussion über die Herausforderungen der traditionellen Psychotherapie und die Vorteile der Hypnotherapie.Ein tiefes Gespräch über die Bedeutung von Aufrichtigkeit und menschlicher Verbindung in der therapeutischen Praxis.Folge Jana Merten auf ihren sozialen Medien, um mehr über ihre Arbeit zu erfahren und tiefe Einblicke in die Welt der Psychotherapie und Hypnotherapie zu erhalten.Janas Homepage: https://www.die-merten-hypnose.de/Instagram: https://www.instagram.com/die_merten_hypnose?igsh=MTAwZzNmM2xja293Yg%3D%3D&utm_source=qrJanas Facebook-Name: Die-Merten-HypnoseDu willst mehr über Sabala und Möglichkeiten mit ihm zusammenzuarbeiten erfahren? Besuche einfach seine Homepage, oder kontaktiere ihn über LinkedIn.Sabalas Homepage
In der heutigen Folge habe ich mich mit Laura Merten von Satte Sache über die pflanzenbasierte Ernährung unterhalten. Laura erklärt unter anderem die Unterschiede zwischen einer veganen und pflanzenbasierten Ernährung und gibt auch Empfehlungen, welche tierischen Produkte man ohne Bedenken zu sich nehmen kann. Wir sprechen darüber, wie sich die pflanzenbasierte Ernährung positiv auf den Körper auswirken kann und haben auch über diese Ernährungsweise während der Schwangerschaft oder Krankheiten gesprochen. Laura gibt uns auch Tipps für die richtige Zubereitung für Hülsenfrüchte, da eine falsche Zubereitung zu Beschwerden nach dem Essen führen kann. ——————————————————— Im Podcast erwähnt: Satte Sache: Website: sattesache.de Podcast: Satte Sache | Ernährung & Wissenschaft Blog Instagram: @sattesache Bücher: Plant Based Endlich Vegan —————————————————— Du möchtest keine Folge verpassen und zusätzliche Tipps direkt in Dein E-Mail Postfach bekommen? Dann melde Dich für meinen Newsletter an und erhalte meine 11 darmfreundlichen Rezepte, die auch Meal Prep geeignet sind. Newsletter & Freebie Deine Gedanken zu meinem Podcastfolge kannst Du mir gerne auf Instagram unter dem Post mitteilen oder auch per Mail zusenden: info@hannah-willemsen.com. Du würdest mir einen riesen Gefallen tun, wenn Du meinen Podcast auf iTunes mit 5 Sternen bewertest. So finden andere diesen Podcast auch und erhalten ebenfalls wertvolle Tipps zum Thema gesunde Ernährung. Alles Liebe Deine Hannah
Merten ja järvien elämän perusta on ihmissilmin näkymätön. Se koostuu mikroskooppisen pienistä kasvi- ja eläinplanktoneista. Niitä ei tule useinmiten ajatelleeksi muulloin kuin kesäisten sinileväkukintojen aikaan. Sonja Repettikään ei ollut ajatellut kasviplanktonia ennenkuin kurkisti mikroskooppiin ja lumoutui näkemästään. Minna Pyykkö jutteli hänen kanssaan hänen kasviplanktontutkimuksistaan ja ensi viikolla Suomenlinnassa avautuvasta planktonien elämää esittelevästä näyttelystään.
Entdecke das Geheimnis deines Mikrobioms, denn deine Darmgesundheit hat große Auswirkungen, z.B. auf dein Immunsystem, deine Haut, deine Stimmung und noch vieles Überraschendes mehr. In der heutigen Folge fachsimpelt Cordelia mit der studierten Ernährungswissenschaftlerin, Buchautorin und Content Marketing Managerin bei BitterLiebe Laura Merten. Finde heraus, wie Probiotika und Präbiotika deine Gesundheit revolutionieren können und wie du dein Mikrobiom optimal unterstützen kannst. Du erfährst wissenschaftlich fundierte Erkenntnisse über Prä- und Probiotika, Tipps und Tricks für ein robustes Mikrobiom und die Verbindung zwischen Mikrobiom und mentaler Gesundheit. Außerdem räumt Laura mit häufigen Missverständnissen und Mythen rund um dieses Thema auf und gibt wertvolle Einblicke, welche Stämme bei Verdauungsstörungen besonders effektiv sein können. Zum Abschluss bekommst du praktische Tipps, wie du mit der Einnahme von Probiotika beginnen kannst und für wen sie möglicherweise nicht so gut geeignet sind. Wenn du erfahren möchtest, wie du deine Darmgesundheit langfristig verbessern kannst, ist die heutige Folge genau richtig für dich.
„Weil es schmeckt“, sagt Laura Merten. In dieser Folge spreche ich mit Laura Merten, sie ist Ernährungswissenschaftlerin und Gründerin von „Satt Sache“. In dieser Episode erfährst du:
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In der der heutigen Folge hört ihr ein Interview mit Laura Merten von Satte Sache. Laura ist Ökotrophologin, Ernährungswissenschaftlerin und Autorin von zwei Büchern. In der Folge haben wir über den Zusammenhang zwischen der Ernährung und dem Immunsystem gesprochen. Du erfährst darin unter anderem wie du über deiner Ernährung das Immunsystem stärken kannst und welche Ernährungsgewohnheiten das Immunsystem eher schwächen. Viel Freude beim Zuhören. Hier geht es zu Laura's Webseite: https://sattesache.de Hier geht es zu Inner Sparkle: https://www.innersparkle.de Mein Darmgesundheits-Buch: https://amzn.to/3trTpq1 Mein 2. Buch „Vegan Ayurveda“ bestellen: http://tastykaty.de/a-vegan-ayurveda Mein 1. Buch „Modern Ayurveda“: https://amzn.to/2NhqgqU
Im heutigen Interview habe ich Laura Merten zu Gast. Laura ist studierte Ernährungswissenschaftlerin und gemeinsam haben wir die Zusammenhänge zwischen Ernährung, dem Immunsystem und der Haut diskutiert. Zunächst haben wir die Aufgaben des Immunsystems besprochen und darüber gesprochen, dass Entzündungen eigentlich eine positive Reaktion des Körpers auf potenziell schädliche Einflüsse sind. Der Unterschied zwischen akuten und chronischen Entzündungen wurde erläutert, ebenso wie die Entstehung von chronischen Entzündungen und ihre Auswirkungen auf den Körper. Wir haben außerdem darüber gesprochen welche Lebensmittel und Lebensstilfaktoren das Immunsystem beeinflussen können. Weiterhin werdet ihr in der Episode mehr über die Zusammenhänge zwischen Ernährung und verschiedenen Hauterkrankungen wie Neurodermitis, Psoriasis und Akne erfahren. Ist glutenfrei, milchfrei, zuckerfrei für jeden sinnvoll? Was ist wirklich gut für die Haut und was sollte man eher meiden? Zuletzt haben wir noch über die Bedeutung der Hydration für die Haut gesprochen und haben einen Blick auf die aktuelle Datenlage zu Kollagen geworfen. Website und Bücher von Laura Merten: https://sattesache.de/buecher/ Laura bei Instagram (@sattesache): https://www.instagram.com/sattesache/?hl=de Hast du Fragen oder Feedback? Schreib mir gern! ✉️ Instagram: https://www.instagram.com/fit__laura/ ✉️ Mail: kontakt@fitlaura.de Meine App - das All in One Paket für deine Gesundheit, hier kannst du dich anmelden: https://www.fitlaura.de/membership/ -jederzeit kündbar -wöchentlich neue Inhalte zu den Bereichen BODY MIND FOOD Mein Nutrition-Bundle: https://www.fitlaura.de/produkt/nutrition-bundle-bowl-kochbuch-ernaehrungsplan/
Vor über 6 Jahren werden wir ein Paar. Ich bin Bodos erste Freundin, wir labeln unsere Beziehung von Anfang an als "offen". Irgendwann knutsche ich das erste mal mit einem anderen Mann und erzähle Bodo davon. Vorher schlafe ich mit einem anderen Mann und erzähle Bodo nicht davon. Zu viel Angst, ihn zu verletzen oder verlieren. Ich verletze Bodo, aber verliere ihn nicht. Ich verliebe mich in Merten und Bodo hat das härteste 3/4 Jahr seines Beziehungslebens. Wir haben immer weniger Sex. Bodo schläft das erste mal mit anderen Frauen, verliebt sich in Annika während ich mich nach 3 Jahren Polyamorie mit 2 Männern von Merten trenne. Bodo ist seitdem glücklich in 2 Frauen verliebt, ich bin seit einem Jahr aus Versehen monogam mit ihm und auch glücklich. Wie wir uns während welcher Phase gefühlt haben, was die größten Verletzungen waren und wie sie geheilt sind, erfahrt ihr in dieser Folge. Seit diesem Jahr arbeite ich als systemische Mediatorin bei Beziehungskonflikten und berate Paare und/oder Einzelpersonen bei Liebes- und Beziehungsthemen. Bei Interesse an meiner Arbeit schreib mir eine unverbindliche Mail an offeneliebe@posteo.de und wir vereinbaren ein erstes Telefonat um zu besprechen, wobei ich dir/euch wie genau helfen kann.
*We've improved this audio!* Due to the style and age of recording for this particular event, some audio quality issues may still persist. We apologize for any inconvenience this may cause.On this episode of the Hayek Program Podcast, we revisit a 2010 event where Professor Emeritus of Economics at George Mason University and Nobel Laureate James M. Buchanan was presented with the Lifetime Achievement Award from the Fund for the Study of Spontaneous Orders at the Atlas Economic Research Foundation.This event was co-hosted by the Fund for the Study of Spontaneous Orders at the Atlas Economic Research Foundation, Liberty Fund, the George Mason University Economics Department, and the Mercatus Center at George Mason University, and took place at George Mason University's Fairfax campus.The panel discussion of Buchanan's work was led by the Dean Emeritus of the GMU Law School, Henry Manne, who was joined by:Amartya K. Sen, Nobel Prize winner in Economic Sciences, 1998, Thomas W. Lamont University Professor and Professor of Economics and Philosophy at Harvard UniversityElinor Ostrom, Nobel Prize winner in Economic Sciences, 2009, Arthur F. Bentley Professor of Political Science, Indiana UniversityJames M. Buchanan, Nobel Prize winner in Economic Sciences, 1986, Professor Emeritus of Economics, George Mason UniversityAlan G. Merten, Former President of George Mason UniversityDaniel Houser, Professor of Economics, George Mason UniversityChris Talley, Former President & CEO of Liberty Fund (now the chairman of the board of trustees for the Winchester Foundation)If you like the show, please subscribe, leave a 5-star review, and tell others about the show! We're available on Apple Podcasts, Spotify, Amazon Music, and wherever you get your podcasts.Virtual Sentiments, our new podcast series from the Hayek Program is now streaming! Subscribe today and listen to season one on digital democracy.Follow the Hayek Program on Twitter: @HayekProgramLearn more about Academic & Student ProgramsFollow the Mercatus Center on Twitter: @mercatusCC Music: Twisterium
Dr. Natascha Merten joins the podcast to discuss her study focused on trends in cognitive function across generations. Merten also explains her research on the associations between sensory and motor functions and blood-based biomarkers for neurodegeneration and dementia. Guest: Natascha Merten, PhD, MS, director, Beaver Dam Offspring Study-Neurocognitive Aging Study, assistant professor, Departments of Population Health Sciences and Medicine, University of Wisconsin–Madison Show Notes Read Dr. Merten's studies, “Better cognitive function in younger generations - Insights from two cohort studies of middle-aged to older adults in Wisconsin,” and “Associations of sensory and motor function with blood-based biomarkers of neurodegeneration and Alzheimer's disease in midlife,” through ScienceDirect. Read Dr. Merten's abstract from the 2022 Alzheimer's Association's International Conference through the journal Alzheimer's & Dementia. Read about Dr. Merten's R01 grant, “Dr. Natascha Merten Awarded NIA Funding To Study Sensory Changes Associated With Cognitive Change” on our website. Learn more about Dr. Merten in her bio on the University of Wisconsin Population Health Sciences website and on her Twitter @NataschaMerten. Connect with us Find transcripts and more at our website. Email Dementia Matters: dementiamatters@medicine.wisc.edu Follow us on Facebook and Twitter. Subscribe to the Wisconsin Alzheimer's Disease Research Center's e-newsletter.
NFC 13 Rückblick mit Mark Bergmann und Andreas Kraniotakes.
Crypto News Alerts | Daily Bitcoin (BTC) & Cryptocurrency News
A widely followed crypto analyst says that the actions of the U.S. Federal Reserve will crash Bitcoin and the crypto markets in general. According to Nicholas Merten, recent testimony from Fed Chair Jerome Powell is likely going to push BTC below the $20,000 level “very soon” as the Fed springs liquidity traps. Merten also notes that the past few weeks have proven just how interconnected crypto is with traditional markets and that Bitcoin bulls should be happy to grab BTC between $13,000 and $14,000 if it were to dip that low. Learn more about your ad choices. Visit megaphone.fm/adchoices
In een driedelige podcastreeks gaan hoofdredacteur Merel Pit en journalist Tracy Metz op zoek naar inspirerende antwoorden op het veranderende winkellandschap (van offline naar online). Leeglopende winkelcentra worden daarom getransformeerd tot woongebieden. Vandaag zijn in deze laatste aflevering te gast architect Marie Wastiau van WilmaWastieau en Merten Nefs, onderzoeker bij de Erasmus Universiteit en TU Delft. Zij vertellen over de verdozing van het Nederlandse landschap die online winkelen onvoorzien heeft meegebracht.
Böse Blutegel, knurrige Kängurus und perfide Penisfische: in diesem „NotAufnahme“-Special gibt es haarsträubende Geschichten rund um „7 vs. Wild“. Knossi und Co hatten keinen Plan von Ebbe und Flut, waren dehydriert und voller Sonnenbrand. Outdoor Medic Ausbilder Torsten und Wildnispädagoge Merten von Hinterland Medics geben exklusive Einblicke zum YouTube-Hit behind the Scenes und sie berichten von medizinischen Notfällen mitten in der Wildnis.
Crypto trader Nicholas Merten, who created the DataDash YouTube channel, shares his opinions on the crypto market, his background and more. He answers questions on past BTC bear cycles, Bitcoin's halvings and other topics. Merten also chats about his history, including how he got his start trading stocks. He offers his take on finding the bottom, trade secrets and the next bull run — the core sections of the show. This interview was recorded on Jan. 9, 2023.Nicholas Merten's Twitter: @Nicholas_MertenBJ's Twitter: @BenjaminPirusCointelegraph's Twitter: @CointelegraphCointelegraph's website: cointelegraph.comIntro and outro music produced by Jonathan “MADic” DeYoung. Hear more at madic.art.The views, thoughts and opinions expressed in this podcast are its participants' alone and do not necessarily reflect or represent the views and opinions of Cointelegraph. This podcast (and any related content) is for entertainment purposes only and does not constitute financial advice, nor should it be taken as such. Everyone must do their own research and make their own decisions. The podcast's participants may or may not own any of the assets mentioned.
Wie wurden Knossi und Co bei „7 vs. Wild“ auf mögliche Unfälle in der unberührten Natur vorbereitet? In diesem „NotAufnahme“-Special schauen wir hinter die medizinischen Kulissen des YouTube-Hits. Outdoor Medic Ausbilder Torsten und Wildnispädagoge Merten von Hinterland Medics geben exklusive Einblicke behind the Scenes und berichten von Unfällen im Nirgendwo: nicht empfehlenswert ist das Stolpern über tödlich-giftige Schlangen, dummgelaufen ist eine Gaskocher-Explosion im Zelt und mit nur 2 % Handyakku sollte sich niemand in der unberührten Wildnis auf den Lofoten verirren…
In der heutigen Podcast Folge habe ich Ökotrophologin und Buchautorin Laura Merten zu Gast. Wir sprechen über anti-entzündliche Ernährung, darüber, welche Fette unserem Körper guttun, was der Haushaltszucker in unserem Körper macht und wieviel okay ist und reden darüber, welche Lebensmittel für ein schönes Hautbild und geringen Haarausfall von Vorteil sind. Hier findest du Laura Merten: Instagram: https://www.instagram.com/sattesache/ Podcast Apple: https://podcasts.apple.com/de/podcast/satte-sache-ernährung-wissenschaft/id1439311547 Youtube: https://www.youtube.com/channel/UCz-JxAP1JuCtonjrPwjPmJw/about Website: https://sattesache.de .................... Viel Freude mit der Episode! Wenn du Fragen oder Feedback für mich hast, schreib mir gerne auf Instagram! @fit__laura / https://www.instagram.com/fit__laura/ *Werbung Mein neues Kochbuch "BOWL IT - gesund & glücklich ohne Verzicht": https://www.fitlaura.de/produkt/kochbuch-bowl-it/ Mein Planer für 2023: https://www.fitlaura.de/produkt/jahresplaner-2023/ ✉️ KONTAKT: kontakt@fitlaura.de
Have you been thinking about other career options outside of working in a traditional Architecture Office? Katie Merten is here to explain all the ins and outs of being an Owner's Representative and why it could be right for you!
Diesmal gibt es eine spezial Ausgabe des Schlagwort Podcasts. Andreas und Mark sprechen mit NFC Matchmaker Max Merten über die Insights des Matchmakings in der MMA Szene. Viel Spaß mit der Folge!
This week, please join author Mads Liisberg and Guest Host Mercedes Carnethon as they discuss the article "Clinical Characteristics, Incidences, and Mortality Rates for Type A and B Aortic Dissections: A Nationwide Danish Population-Based Cohort Study from 1996 to 2016." Dr. Carolyn Lam: Welcome to Circulation on the Run, your weekly podcast summary and backstage pass to the journal and its editors. We're your co-host. I'm Dr. Carolyn Lam, Associate Editor from the National Heart Center and Duke, National University of Singapore. Dr. Greg Hundley: And I'm Dr. Greg Hundley, Associate Editor, Director of the Poly Heart Center at VCU Health in Richmond, Virginia. Dr. Carolyn Lam: Greg, today's feature paper is about aortic dissections and it's the first nationwide population based study investigating the clinical characteristic, incidents, and mortality based on validated diagnosis of aortic dissection in a national patient registry. You want to hear more? Well, you have to just keep listening. Let's go on though first to discuss the other really important papers in today's issue, shall we? Dr. Greg Hundley: Absolutely. Dr. Carolyn Lam: You know what, Greg? I'm going to start while you grab a coffee. I want to talk about high sensitivity cardiac troponins and how they have allowed the use of strategies in the emergency department, for example, to rapidly rule out acute MI within one to three hours and potentially facilitate early discharge of low-risk patients. Now, the ability to rapidly rule out MI of course depends on the turnaround time of these high sensitivity cardiac troponin results from the central laboratory, which is often delayed due to specimen transport and handling and all these things. So, point-of-care assays can reduce this turnaround time by even 40 minutes, and early studies have actually used frozen plasma bio banks to assess these point-of-care assays... But no study has evaluated these point-of-care assays with fresh whole blood to safely rule out MI in the emergency department. That is until today's paper. So in today's study led by corresponding other Doctor Fred Apple from Hennepin Medical Center in Minneapolis, Minnesota and his team, they aimed to derive and validate an optimal high sensitivity cardiac troponin threshold concentration using whole blood point-of-care troponin eye assay on a single sample at presentation in the emergency department to identify patients at low risk of index MI for potential early discharge. Dr. Greg Hundley: Fascinating study Carolyn. So point-of-care testing, high sensitivity troponin from whole blood in the ED. So what did they find? Dr. Carolyn Lam: Among consecutive emergency department patients from two prospective observational studies with suspected acute coronary syndrome, a point-of-care, whole blood, high sensitivity cardiac troponin eye assay, the Atellica VTli provided a sensitivity of 98.9% and a negative predictive value of 99.5% for ruling out MI. A single measurement using a cutoff of less than four nanograms per liter for whole blood was successful in rapidly identifying patients at low risk of MI cardiac and all cause death and unplanned revascularization at 30 days. Dr. Greg Hundley: Very nice Carolyn, and could be quite practical. So Carolyn, my next paper comes to us from the world of preclinical science and it pertains to cardiac regeneration. So cardiac regeneration after injury is limited by the low proliferative capacity of adult mammalian cardiomyocytes. However, certain animals readily regenerate lost myocardium via process involving dedifferentiation, which unlocks their proliferative capacities. So inspired by this concept, these investigators led by Professor Patrick Hsieh from Academic Sinica, generated mice with inducible cardiomyocyte specific expression of the Yamanaka factors enabling adult cardiomyocyte reprogramming and dedifferentiation in vivo. Dr. Carolyn Lam: Wow. So what did they find, Greg? Dr. Greg Hundley: Right, Carolyn. So two days following induction, adult cardiomyocytes presented with a dedifferentiated phenotype, an increase proliferation in vivo. Microarray analysis revealed that the up-regulation of ketogenesis was central to this process. Now adenovirus driven HMGCS2 over-expression induced ketogenesis in adult cardiomyocytes and recapitulated cardiomyocyte dedifferentiation and proliferation observed during partial reprogramming. This same phenomenon was found to occur after myocardial infarction, specifically in the border zone tissue. And HMGCS2 knockout mice showed impaired cardiac function and response to injury, and so in summary, Carolyn, these data demonstrated the importance of HMGCS2 induced ketogenesis as a means to regulate metabolic response to cardiomyocyte injury, thus allowing cell dedifferentiation and proliferation as a regenerative response. Dr. Carolyn Lam: Wow, that's so cool. From cell regeneration to autoimmunity in this next paper. Now autoimmunity is increasingly recognized as a key contributing factor in heart muscle diseases. However, the functional features of cardiac autoimmunity in humans remain undefined due to the challenge of studying immune responses in situ. Now, these authors previously described a subset of c-Met expressing memory T lymphocytes, which preferentially migrate to cardiac tissue in mice and humans. In today's study, these authors led by co-corresponding authors, Dr. Federica Marielli-Berg and Saidi Mohidden from William Harvey Research Institute, Barts and the London Faculty of Medicine and Dentistry, and Queen Mary University of London, and their colleagues performed in-depth phenotyping of peripheral blood T cells in groups of patients with inflammatory and non-inflammatory cardiomyopathies, patients with non-cardiac autoimmunity and healthy controls... And they found that c-Met positive T cells were selectively increased in the circulation and in the myocardium of patients with inflammatory cardiomyopathies. The phenotype and function of c-Met positive T-cells were distinct from c-Met negative T cells, including preferential proliferation to cardiac myosin and co-production of multiple cytokines. Further, circulating c-Met positive T cell subpopulations in different heart muscle diseases identified distinct and overlapping mechanisms of heart inflammation. Furthermore, validation studies in experimental autoimmune myocarditis showed that elevations of auto-antigens specific c-Met positive T cells in peripheral blood, marked the loss of immune tolerance to the heart. Importantly, disease development could be halted by pharmacologic c-Met inhibition indicating a positive role for these c-Met positive T cells. Dr. Greg Hundley: All right, Carolyn, as you always ask me. So what's the take home message here? Dr. Carolyn Lam: This study demonstrates that the detection of circulating c-Met positive T cells may have utility in the diagnosis and monitoring of adaptive cardiac inflammation and additionally defined new targets for therapeutic intervention when cardiac autoimmunity causes or contributes to progressive cardiac injury... And this is discussed in an editorial by doctors at Abplanalp, Merten, and Dimmeler. Dr. Greg Hundley: Very nice, Carolyn. Wow. More fantastic preclinical science. Well, in the mail of the bag today, there is a Research Letter by Professor Burr entitled “Cannabis Inhalation Acutely Reduces Muscle Sympathetic Nerve Activity in Humans.” Dr. Carolyn Lam: There's an ECG Challenge by Dr. Reddy entitled “Shortness of Breath and Near Syncope During Exertion In a Child, When Patient Worry Syndrome.” There's also a Perspective by Dr. Weitz on what is the future of Factor 11 inhibitors. Dr. Greg Hundley: Well Carolyn, I'm looking forward to learning more about aortic dissections and that large Danish population-based study. Wow. Dr. Carolyn Lam: That's great. Let's go Greg. Dr. Mercedes Carnethon: Well, welcome to this episode of Circulation on the Run. My name is Mercedes Carnethon, an Associate Editor of Circulation, and Professor and Vice Chair of Preventive Medicine at Northwestern University. I'm really excited today to be here with the senior author of a really exciting paper that we're featuring on clinical characteristics, incidences and mortality rates for aortic dissections type A and B, a nationwide Danish population-based cohort study, and we have with us today Mads Liisberg. So welcome today. Dr. Mads Liisberg: Thank you. Dr. Mercedes Carnethon: So thank you so much for joining us and really thank you for sharing your important research with Circulation. This topic is so critically important, particularly given the high mortality rates associated with aortic dissections. Can you tell us a little bit about the work that you and your co-authors did in this important space? Dr. Mads Liisberg: Yes. Well actually the work originated when I started my PhD thesis and we got a registry data dump from the Danish medical registries and we found that almost none of our patients in the registry were registered with a specific aortic dissection code. So we did a validation study on the same time period from 1999 to 2006 where we went through all these medical records to ensure that we had the right aortic dissection TC 10 codes on population. Then we went a bit further and looked at the clinical characteristics of this patient, 'cause that's one of the really major things about Danish medical registries in our country, is that we have access to not only every patient's specific in hospital contacts, but also their medicine abuse, their drug use based on a TC code. So we can go really deep into each and everyone's drug history. When we did this study, we wanted to find out if the incidence rates during this timeframe had changed, which we find that it did, but also looking at mortality rates because, as you said, it's really high risk disease to be diagnosed with. So that's more the rationale for this study. Dr. Mercedes Carnethon: Thank you so much for sharing that. Certainly we know that the mortality rates from this are very high. I note that you report some changes over time between 1996 and 2016 in the incidents of these types of aortic dissections. So what did you find about the patterns of change in type A aortic dissections? Dr. Mads Liisberg: We found that it almost doubled from the beginning of our time period to the last, and the question is why is this? 'Cause that's one of the thing that the data doesn't reveal. We are only able to see that the incidence actually rises, but is it because that they are underdiagnosed in the beginning? Or is it because that we are better diagnosing in the end of the study that really are progressed? Dr. Mercedes Carnethon: That's a good question. I noted that when you studied the correlates of aortic dissection, you identified a number of characteristics and what stood out to me was the finding about the strong association of hypertension. I'm less aware of patterns of hypertension in the Danish population. Do you think that the changes in the prevalence of hypertension in the population contributed at all to these findings? Dr. Mads Liisberg: Well, most certainly, 'cause when you look at the prevalence of hypertension throughout any person's lifespan, the older they get the more likely they are to suffer from hypertension, and the Danish population has aged quite a lot in recent years. So I think that's one of the main reasons we find this, and also that most of our arctic dissection patients are actually quite old, which would correlate with hypertension as well. Dr. Mercedes Carnethon: One thing I really like, and you pointed this out, is really the richness of the data that you have in your health system, and I wonder, just going even a little deeper on the hypertension question, given that it is the most common medical diagnosis worldwide, were you able to study characteristics of hypertension that would be more strongly associated with aortic dissection? So for example, duration of hypertension, severity, prevalence of hypertension control? Dr. Mads Liisberg: That's actually a funny question 'cause the last study of my thesis, which hasn't been published yet or even submitted for that fact, examines the correlation between use and the risk of arctic dissection. On a very specific level, the way that hypertension is treated mostly in Denmark is with your general practitioner. So the way that we examine in studies like these, is that we look at prescription drug use. So if we find that an individual has a TC codes corresponding with anti-hypertensive drugs, then we are able to code them as hypertensive patients. Dr. Mercedes Carnethon: Okay, thank you for that. I always... I'm an epidemiologist myself, so I really love to see great population science studies and this registry is large, you have long-term follow up and you've got a great deal of data, but those people who feel as though it's obviously not appropriate to make causal conclusions around epidemiology and that perhaps epidemiologic findings shouldn't be driving clinical decision-making. In response to that, I think I would pose the question to you, which is how do you see clinicians and providers using this information from your observational study? Dr. Mads Liisberg: I think that's rather difficult. One of the findings that we present is to pose it over mortality for type B dissections when we exclude the 30-day mortality, but then we show that type A dissections have almost a corresponding mortality rate compared to a hypertensive cohort... And this finding is difficult to draw any clinical conclusions from, but there's actually a Danish randomized controlled trial just starting up in the next year. I think it's called the Sunday trial, where they will include all uncomplicated type B dissections and randomize them for treatment or no treatment, and the issue here is that you'll probably be over-treating some patients and under-treating others, but this discussion with the uncomplicated type B dissection has been ongoing for so many years. So it's difficult for me to just give one golden answer. Dr. Mercedes Carnethon: Certainly, and I appreciate the caution as we certainly don't want to overstep our findings. You did make a recommendation in the conclusion that it might be beneficial to treat type B aortic dissections more aggressively. Is this what you're alluding to, based on the other study that you're referencing? Dr. Mads Liisberg: Yes, yes, definitely. We see some clinicians being more cautious treating type B dissections with a TIVA or a surgery. So it's a difficult thing when they're uncomplicated, why treat them? But they can't be or become complicated quite easily and fast and then it's a difficult thing, because should you have treated them earlier? Or do you need to treat them now in their acute phase? Or wait for a chronic phase? It's a really good question. Dr. Mercedes Carnethon: No, I appreciate that and what I really love are the types of research studies that leave you with many more questions and next steps, and so I would like to really sort of bring us to a close with the big picture question, which is what do you see as the next steps in this line of research, given really what we all agree on is a very significant clinical problem. Dr. Mads Liisberg: We would really like to expand our database with even more clinical data as of now and include any image diagnostics for our cohort. So we're might be able to see any trends in our modulation before the dissection occurs. If any of our patients have any diagnostics done prior to being diagnosed. Dr. Mercedes Carnethon: I really want to thank you today for spending time talking with us. I know that our readers rarely have an opportunity to hear from everybody behind the scenes views on what the rationale was for carrying out a paper and really how the authors themselves hope that the paper will be used. So I really thank you for sharing that with us today, Matts, on behalf of your co-authors, this has been really a wonderful conversation, and thank you again for sharing your research with the journal, Circulation. Dr. Mads Liisberg: Oh, thank you for having me in for accepting our paper. Dr. Mercedes Carnethon: So thank you so much to our listeners for listening to us on this episode of Circulation on the Run. Please tune in next week as we will have more exciting insights. Dr. Greg Hundley: This program is copyright of the American Heart Association 2022. The opinions expressed by speakers in this podcast are their own and not necessarily those of the editors or of the American Heart Association. For more, please visit ahajournals.org.
3 Jahre freie Beziehung, offene Liebe, Gefühle für andere, Sex mit anderen. Merten erzählt von seiner größten Herausforderung damit in diesem Jahr und wie er einen Umgang mit Ängsten und Vergleichsgefühlen gefunden hat. Hilft es, die anderen Menschen kennenzulernen? Ist Eifersucht irgendwann einfach weg? Müssen und wollen wir uns immer alles erzählen? Diese und viele weitere Fragen beantworten wir euch. Für Fragen und Feedback schreibt bei Instagram an @lebenliebenpodcast
Heute gibt es eine knackige Zusammenfassung mit niemand geringerem als Andreas Kraniotakes und Enriko Kehl zu GLORY 82, des weiteren sind Max Merten und Emilio Quissua im Interview mit unseren beiden Hosts des Schlagwort Podcasts. Viel Spaß mit der neuen Folge und immer schön cremig bleiben!!!
In today's episode, we speak with Donna Merten, an award-winning architectural designer, real estate developer, and food systems strategist.Donna is currently the Chief Forager and co-owner of the FED food truck in Boulder, CO and is passionate about bringing back artisanal culinary practices and reducing food waste. She is also turning restaurant methodology inside out and seeking to create a whole new way of working with local food. Listen as Donna talks about getting back to old farm practices, building sustainable local food systems, and relearning how we approach food and eating.
Warum arbeiten immer mehr Menschen an ihrer Persönlichkeit? Woher kommt der ganze Hype um Selbstbewusstsein, Mindset, Vision und Co.? Die Antwort ist simpel: Wenn du eine stabile Persönlichkeit besitzt und dir bewusst bist, in welche Richtung du dich (wirklich) entwickeln willst, dann bist du mit dir selbst im Reinen. Doch dafür muss zunächst deine Basis stimmen. Bedeutet: Du musst dich selbst besser kennenlernen. Was zeichnet deinen Charakter aus? Welche Talente, Wünsche und Träume hast du? Was sind deine Ziele, Stärken, Schwächen, Ängste und Hoffnungen?
Neste segundo episódio tivemos a honra de conversar com o professor Gustavo Henrique Merten direto de Duluth em Minessota. O professor Gustavo fez grandes contribuições para os estudos de manejo conservacionistas no Brasil e conta um pouco disso para nós. Além disso, ele também é um grande estudioso e conta com detalhes os aprendizados que os americanos tiraram dos grandes erros que cometeram no passado. Será que estamos no caminho certo? Você pode achar esse episódio longo demais, mas mesmo que em partes, não deixe de escutar todo ele. Você vai se surpreender com o tanto que o BR já fez em termos de conservação do solo e tirar suas próprias conclusões sobre a situação atual da conservação do solo e da água no Brasil em relação aos EUA. www.agroconnection.net - Instagram/Facebook/Twitter: @oagroconnection
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Crypto News Alerts | Daily Bitcoin (BTC) & Cryptocurrency News
Data Dash host Nicholas Merten says Bitcoin and the crypto markets are setting up for a big parabolic comeback over the coming months as he's becoming more and more convinced that a spring cryptocurrency rally is imminent. Merten makes the case that BTC will soon be back to $60,000, a price range not seen since November 2021. Merten also says the altcoin market, already gaining momentum, will rally in turn. “I want to make the case that, really, as soon as later in April, if this trend plays out here, we could be back up towards that $60,000 range for Bitcoin. We could be in for a spring rally… But it's not just Bitcoin. I want to emphasize this big time – because I understand all the while Bitcoin is obviously the most recognized currency, it is the largest crypto in the crypto space – this is unlikely to be just a Bitcoin rally." Learn more about your ad choices. Visit megaphone.fm/adchoices