Podcasts about Thum

                                                   BLACK SHIRT MIXTAPE                                                       **Episode 114**                                                                                         Join host Jesse Karassik aka @heyyyyy_jesse as he takes you on a 2 hour sonic journey playing mixtape inspired tracks in a variety of genres- all for your listening (dis)pleasure!   Tracklisting:   1. The Twilight Kid...The Twilight Singers 2. Killing Lies...The Strokes 3. From...Bon Iver 4. While We Go Dancing...White Rabbits 5. Aperture...Harry Styles 6. I Heard...Corina Grove 7. Electric Feel...Henry Green 8. I Only Have Eyes For You...Beck 9. Boycott Heaven...The Format 10. THUM...Violet Grohl 11. Wake Up...The Walkmen 12. Leif Erikson...Interpol 13. Tree Among Shrubs...Men I Trust 14. Ladies and gentlemen we are floating in space...Spiritualized 15. No One Noticed...The Marias 16.Murderer...Low 17. Sweet Jane...Cowboy Junkies 18. Passin' Me By...The Pharcyde 19. 3 Libras...A Perfect Circle 20. Pitseleh...Elliott Smith 21. Sam's Town (Live From Abbey Road)...The Killers 22. This Scene Is Dead...We Are Scientists 23. The Ghost At Number One...Jellyfish 24. The Guns of Brixton...The Clash  

Greg Belfrage Interviews the Sioux Falls Police Chief, Jon Thum, and officer Aaron Benson about what's going on at the Sioux Falls Police Department. They went over the recent case of Joel Taken Alive, the upcoming release of public safety statistics, hiring for the department, impaired driving, simulated weapon (BB guns) penalties, stolen cars, voting, and the Superbowl. See omnystudio.com/listener for privacy information.

MUSICViolet Grohl, daughter of Dave Grohl, released her first two solo singles, "THUM" and "Applefish", on Dec. 5. ICYMI: Filter, Filter Eleven and Local H are teaming up for a spring tour that starts March 5th in Wenatchee, Washington and wraps up April 1st in Cleveland. Tickets go on sale Friday. It looks like Oasis fans will definitely have to wait until 2027 to see the band again. Liam Gallagher answered fans' questions on X about continuing their reunion tour, and when one fan asked him to announce dates for next year already, Gallagher replied: “We're not doing anything in 2026 sorry.” Loudwire.com published a list of five '70s rock stars who never drank or did drugs. Could they seriously only find FIVE? https://loudwire.com/1970s-rock-musicians-no-drugs-alcohol/ 1. GENE SIMMONS2. FRANK ZAPPA3. ANGUS YOUNG4. TOM SCHOLZ5. TED NUGENT TVTwo TV critics from "Variety" chose the 10 best shows of 2025. List 1:1. "Adolescence", Netflix2. "The Pitt", HBO Max3. "Forever", Netflix4. "Paradise", Hulu5. "It: Welcome to Derry", HBO6. "Outlander: Blood of My Blood", Starz7. "A Thousand Blows", Hulu8. "Untamed", Netflix9. "The Gilded Age", HBO10. "Murdaugh: Death in the Family", Hulu List 2:1. "Andor", Disney+2. "Long Story Short", Netflix3. "The Pitt", HBO Max4. "Dying for Sex", FX5. "The Righteous Gemstones", HBO6. "Everybody's Live with John Mulaney", Netflix7. "The Lowdown", FX8. "The Gilded Age", HBO9. "Pluribus", Apple TV10. "The Studio", Apple TV https://variety.com/lists/best-tv-shows-2025/ MOVING ON INTO MOVIE NEWS:Best movies of 2025 … Rolling Stone just released their list of the Top 20 movies of 2025. These are the Top 5. The question is … Did you see any of them? Did you see any of them in the theater?Nouvelle Vague (5) Train Dreams (4) Black Bag (3) Hamnet (2) One Battle After Another (1) I've never wanted a celebrity relationship more than I want Pamela Anderson and Liam Neeson. Unfortunately, it sounds like it's not happening. At least not anymore. On the bright side, it sounds like they're in a really good place. https://people.com/pamela-anderson-on-liam-neeson-relationship-exclusive-11864356 AND FINALLY'USA Today' has picked its list for the worst Christmas songs of all time. They are: Alvin and the Chipmunks, ‘The Chipmunk Song (Christmas Don't Be Late)' Elmo and Patsy, ‘Grandma Got Run Over By a Reindeer'NewSong, ‘The Christmas Shoes' Jessica and Ashlee Simpson, ‘The Little Drummer Boy' New Kids on the Block, ‘Funky Funky Xmas' 'USA Today' called their number one pick for worst Christmas song "the novelty song from Hell."Sure there's those annoying Christmas songs we hear every year . . . but let's take it up a notch with Christmas carols from HELL. 1. "Here Comes Santa Claus" by Mrs. Miller. She was discovered by the announcer from "Laugh-In", which should tell you all you need to know.2. "Silent Night" by Wing. Wing Han Tsang was from Hong Kong and started singing as a hobby when she moved to New Zealand. Surprisingly, she made it kinda big. "South Park" even parodied her back in the day.3. "White Christmas" by Tiny Tim. There's also "Silent Night", featuring a spoken-word break where he takes aim at hypocrites, fornicators, and child molesters. You know, just regular Christmas caroler stuff. 4. "Little Drummer Boy" by William Hung. Isn't it crazy to think there's a whole generation who has no idea who this "American Idol" treasure is? 5. "I Got a Cold for Christmas" by the Three Stooges. Not terrible, but not exactly a classic.6. "Jingle Bells" by William Shatner, featuring Henry Rollins. Yes, THAT Henry Rollins.7. "Santa Claws Is Coming to Town" by Alice Cooper, featuring John 5, Billy Sheehan, and Vinny Appice. 8. "The Night Before Christmas" by David Hasselhoff. This one is extra cheesy, but did you expect anything less?9. "Rudolph the Red-Nosed Reindeer" by Regis Philbin. This one has a cameo by a pre-Oval Office Donald Trump, who offers Rudolph a job in place of Santa.10. "Jingle Hell" by Christopher Lee. Yes, one of the greatest actors of all time. He dabbled in heavy metal later in life. This actually isn't his only holiday song, either. He also did covers of "The Little Drummer Boy" and "Silent Night".11. "Away in a Manger" by the Brady Bunch. This one only features the vocal talents of Marcia, a.k.a. Maureen McCormick. It's from an album called "Merry Christmas from the Brady Bunch".See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Greg Belfrage interviews the Sioux Falls Police Chief and Communications Officer Sargeant Aaron Benson. They talk about the winter weather and plowing, the decrease in crime statistics, preventing packages from getting stolen, mentoring programs, and more...See omnystudio.com/listener for privacy information.

HADITH 01-06: The Mercy and Character of Prophet Muhammad ﷺ | ZAD Academy Audio | Blogpost by Zayd HajiBy Zayd Haji – Student at ZAD AcademyAssalamu Alaikum wa Rahmatullahi wa Barakatuh,In this lecture from Hadith Semester 1 by Shaykh Dr. Muhammad Salah, we explore the profound mercy and noble character of Prophet Muhammad ﷺ as taught through authentic Hadith and Qur'anic verses.Allah sent Prophet Muhammad ﷺ as a mercy to all humanity. The Qur'an states:“And We have not sent you, [O Muhammad], but as a mercy to the worlds.”(Surah Al-Anbiya 21:107, quran.com/21/107)This mercy encompassed the weak and strong, friend and foe, rich and poor, even extending to animals and the environment. The Prophet's ﷺ mercy was a reflection of Allah's infinite compassion.Allah describes the Prophet's character as exemplary:“And indeed, you are of a great moral character.”(Surah Al-Qalam 68:4, quran.com/68/4)His life models humility, patience, kindness, and forgiveness. For example, when a child urinated on him, he calmly cleaned himself without anger, showing compassion in every circumstance.The Prophet's mercy extended to enemies as well, exemplified in the story of Thumāmah ibn Uthāl, who embraced Islam after witnessing the Muslims' kindness and tranquility.Abu Hurairah (May Allah be pleased with him) reported: Messenger of Allah (ﷺ) said, "Allah has divided mercy into one hundred parts; and He retained with Him ninety-nine parts, and sent down to earth one part. Through this one part creatures deal with one another with compassion, so much so that an animal lifts its hoof over its young lest it should hurt it". [Al-Bukhari and Muslim]Another narration is: Messenger of Allah (ﷺ) said, "Allah has one hundred mercies, out of which He has sent down only one for jinn, mankind, animals and insects, through which they love one another and have compassion for one another; and through it, wild animals care for their young. Allah has retained ninety-nine mercies to deal kindly with His slaves on the Day of Resurrection." [Al-Bukhari and Muslim].Another narration in Muslim is reported: by Salman Al-Farisi: Messenger of Allah (ﷺ) said, "Allah has hundred mercies, out of which one mercy is used by his creation for mutual love and affection. Ninety-nine mercies are kept for the Day of Resurrection."Another narration is: Messenger of Allah (ﷺ) said, "Allah created one hundred units of mercy on the Day He created the heavens and the earth. Each one of them can contain all that is between the heaven and the earth. Of them, he put one on earth, through which a mother has compassion for her children and animals and birds have compassion for one another. On the Day of Resurrection, He will perfect and complete His Mercy". (That is He will use all the hundred units of mercy for his slaves on that Day).Riyad as-Salihin 420https://sunnah.com/riyadussalihin:420Islam teaches that acts of leadership must lead with compassion and reconciliation rather than dominance.ConclusionThe Hadith and Qur'an together portray the Prophet whose mercy and character are central to his message. His compassion teaches us to be merciful, forgiving, and patient, embodying the beautiful ethics of Islam.

Greg Belfrage interviews the Sioux Falls Chief of Police Jon Thum and Public Information officer Seargeant Aaron Benson. They talk about the crime statistics and how they handled the street racing, and what people can do to help prevent crimes from happening. See omnystudio.com/listener for privacy information.

#dtalk #DNEWS24 #MarcelThum #IFO #Rente #Demografie #Babyboomer #Renteneintrittsalter #Lebensarbeitszeit #UmlageverfahrenOhne umfassende Reform droht das gesetzliche Rentensystem zu implodieren. Wissenschaftler um Ko-Autor Professor Dr. Marcel Thum vom IFO-Institut legen Reformoptionen vor. Im DTalk in DNEWS24 stellt Professor Thum die Reformpläne vor und sagt, was er von der Bundesregierung fordert.

Greg Belfrage interviews Sioux Falls Police Cheif Jon Thum about all the changes that are happening with the police starting to work with ICE.See omnystudio.com/listener for privacy information.

Ih Homone Te A Balance Theih Nang // Health Talk.Kawikawi + Aw Nem // Chin Gospel SOngs.

Ih pumpi ii ong hilh kholh Signs te thu // Health talk.Kawikawi + Pai Zel Ding // Chin Gospel Songs.

See omnystudio.com/listener for privacy information.

On the first Sabbath Sunday of 2025, Dave is joined by Adam Sieff and the Bishop of Sioux Falls, Dennis Thum, for a conversation about the Sabbath. We hope it encourages you as you seek grace, truth, and life.

See omnystudio.com/listener for privacy information.

Steffen Thum is a German composer for film, TV, games and advertising, based in Berlin. With over 70 credits to his name, he has extensive experience across high profile studio films, independent cinema, TV and advertising campaigns. Max Aruj is a composer born and raised in Los Angeles. His recent projects include MoviePass, MovieCrash (HBO), Lansky starring Harvey Keitel, and The Ice Road (Netflix) starring Liam Neeson. Both are successful film composers with experience working on high profile projects with composers such as Lorne Balfe, Hans Zimmer and others. They're here to talk with us today about collaboration, lessons learned in their careers, and their work on the film “Betrayal.” Topics Include: *Working for another composer is another level of training and “school” *The importance of working very cleanly and clearly in collaboration *Work at a high level to hone your craft *The importance of attention to detail *Behind the score of “Betrayal” *Advice for aspiring musicians https://www.steffenthum.com/ https://maxaruj.com/

On this episode, I'm joined by Ben, bassist for the band Skull Gate, to discuss growing up in the Ottawa scene, sugary coffees, Eggnog haters, writing most mosh-worthy thrash riffs, and Veils, the newest release from Skull Gate. During the episode I was drinking Sumava from Pilot Coffee Roasters. Episode Links: https://pilotcoffeeroasters.com/ https://skullgate.bandcamp.com/music https://www.beansandbreakdowns.com/

In this special episode of The Lawyers Weekly Show, produced in partnership with The College of Law, we reflect on how the new Right to Disconnect laws can and will facilitate mindset and communication shifts in professional services workplaces and why those in law should see these laws as a “moment for potential growth”. Host Jerome Doraisamy speaks with Florence Thum, a lecturer and assistant director in NSW for PLT at The College of Law, about her reflections on the advent and passage of the new Right to Disconnect laws, the need for law firms to realign their priorities, adopting a back-to-basics approach and what this looks like, and what meaningful, transparent communication should look like in the new normal. Thum also delves into how individual lawyers can better advocate for themselves in evolving workplaces, making changes to the organisational mindset, building new communication strategies upon a foundation of respect and trust, the challenges that legal workplaces may face in undergoing such a realignment, and why the legal profession needs to see the Right to Disconnect laws as a “moment for potential growth”, and employ empathy in a technologically driven world. To learn more about The College of Law, click here.

„Deutsche Wirtschaft in der Flaute“, schreibt die Taz und die FAZ warnt im Juli 2023 „Der deutsche Wohlstand sei in Gefahr“. Auf YouTube sprießen aus allen Ecken Selbsternannte Finanzexperten empor, die uns erzählen wollen, wie wir binnen weniger Tage ein Vermögen erschöpfen und der Inflation entgehen könnten – man brauche nur die richtige Methode Oder […] Der Beitrag Wirtschaft im Wahlkampf. Ein Gespräch mit Ifo-Leiter Professor Dr. Marcel Thum erschien zuerst auf Campusradio Dresden.

Sioux Falls Police Chief Thum hopes to learn more about the recent shootings and homicides in our city. Plus other police issues that question the safety of residents in the Sioux Falls Metro.See omnystudio.com/listener for privacy information.

One of the most beautiful voices in CCM history belongs to one of the most beautiful people I've ever met on my musical journey. Pam Thum grew up with parents who were traveling evangelists and carried their heart for seeing people meet Jesus into her solo career. It's been way too long since she and I had the chance to talk, so sit back and relax as two old friends catch up on life and careers and tell a few fun stories along the way.Support the showandychrisman.com

One of the most beautiful voices in CCM history belongs to one of the most beautiful people I've ever met on my musical journey. Pam Thum grew up with parents who were traveling evangelists and carried their heart for seeing people meet Jesus into her solo career. It's been way too long since she and I had the chance to talk, so sit back and relax as two old friends catch up on life and careers and tell a few fun stories along the way.Support the Show.andychrisman.com

Kutties (குட்டீஸ்)  Under the Tree is an initiative to promote book reading, the stories are told in Tamil language for the children to motivate them to read Tamil

Achtsamkeitspraxis ist auch wichtig für unsere Darmgesundheit. Denn: So wie unser Darm aussieht, so geht es auch unserem Gehirn.Hier geht's zum Podcast Seelenfänger vom BR.**********Quellen aus der Folge:Cryan, J. F., & Mazmanian, S. K. (2022). Microbiota–brain axis: Context and causality. Science, 376(6596), 938-939. Schneider, K. M., Blank, N., Alvarez, Y., Thum, K., Lundgren, P., Litichevskiy, L., ... & Thaiss, C. A. (2023). The enteric nervous system relays psychological stress to intestinal inflammation. Cell, 186(13), 2823-2838. Wang, Z., Liu, S., Xu, X., Xiao, Y., Yang, M., Zhao, X., ... & Wang, T. (2022). Gut microbiota associated with effectiveness and responsiveness to mindfulness-based cognitive therapy in improving trait anxiety. Frontiers in cellular and infection microbiology, 12, 719829. Darmfreundliche Ernährung**********Dianes und Main Huongs Empfehlungen:Axt-Gadermann, M. (2022). Gesund mit Darm. Fitter, gelassener und jünger mit dem richtigen Mikrobiom. Südwest. **********Mehr zum Thema bei Deutschlandfunk Nova:Ikigai: Wie wir Sinn und Zufriedenheit im Leben findenPsychotherapie: Das "innere Kind" in den Arm nehmenGartenarbeit: Draußen im Grünen sein ist Achtsamkeit**********Den Artikel zum Stück findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: Tiktok und Instagram.**********Ihr habt Anregungen, Ideen, Themenwünsche? Dann schreibt uns gern unter achtsam@deutschlandfunknova.de

[PODYSSEY] PC (Rolf Thum|Katrin Exner)

[PODYSSEY] Die Bestimmung (Rolf Thum|Verena Wilhelmy)

[PODYSSEY] Die Bestimmung (Rolf Thum|Verena Wilhelmy)

[PODYSSEY] PC (Rolf Thum|Katrin Exner)

Sioux Falls Police Chief Thum drops in on The Greg Belfrage Show. See omnystudio.com/listener for privacy information.

Ih Homone Te A Balance Theih Nang // Health Talk.Kawikawi + Aw Nem // Chin Gospel SOngs.

Ih pumpi ii ong hilh kholh Signs te thu // Health talk.Kawikawi + Pai Zel Ding // Chin Gospel Songs.

I am joined by Dr Yau Thum from the Lister to discuss Reproductive Immunology. Reproductive Immunology looks at how the immune system and the reproductive system can impact conception and pregnancy. It is an area that is explored and tested when people have experienced repeat implantation failure and/or miscarriage with no other explanation found. Dr Yau Thum leads the reproductive immunology research team at The Lister Fertility Clinic. He has been involved in research in the area of natural killer cells and immunological aspects of recurrent failed implantation since 2003 and have published papers demonstrating that an "overactive" immune system may negatively affect pregnancy outcomes and IVF success rates. In this episode we discuss: What is reproductive immunology? The problem with researching this area. What tests can you do to test this area? Killer cells what they are, how you test for them? What the cytotoxicity test is. Drug protocols to address these issues and when to start them Who should take the tests. Why they are so expensive. Where to find out more about reproductive immunology. If you want to learn more please see The Lister Fertility Clinic Pages and/or the Reproductive Immunology Centre. You can also find out more via HFEA

Bert sits down with a couple important people from our area, Sioux Falls' police and fire chiefs this hour to talk what's new within the respective departments, and also get a few bold big game predictions!

Sioux Falls Police Chief Thum drops in on The Greg Belfrage Show.See omnystudio.com/listener for privacy information.

This episode is set to inspire the structure of your marketing team, whether small, medium or colossal. Our guest, Eric Thum, Head of Marketing at VTS, was a winner of our FINITE 30 this year as he has led the marketing for one of the fastest-growing B2B SaaS companies in 2023. You'll get an inside scoop into how he's achieved this - through an integrated team structure, aligned metrics and more. The FINITE Podcast is made possible by:- Clarity: the fast growing, global marketing communications agency working with leading technology brands.- 93x: the leading digital marketing agency for B2B technology, software & SaaS businesses delivering SEO & PPC strategy that drives leads, pipeline & revenue growth.- And Exclaimer: the industry's leading provider of email signature solutions, empowering businesses to unlock the potential of email as a key digital advertising channel. Support the show

Matthew is here! Yes. He is back! Anotha one! Matthew starts off slow but finishes with a BANG! He talks about how the big toe doesn't have a unique name like the thumb, his trip to netherlands in a week, and much much more! Zip Zappity Doo! Love you if you listen. For real.

Substantiv

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.03.01.530580v1?rss=1 Authors: Singh, S., Gaur, A., Kumari, R., Prakash, S., Kumari, S., Chaudhary, A. D., Sharma, R. K., Prasun, P., Pant, P., Thum, T., Jagavelu, K., Bharati, P., Hanif, K., Chitkara, P., Kumar, S., Mitra, K., Gupta, S. K. Abstract: Regulation of RNA stability and translation by RNA-binding proteins (RBPs) is a crucial process altering gene expression. Musashi family of RBPs comprising Msi1 and Msi2 are known to control RNA stability and translation. However, despite the presence of MSI2 in the heart, its function remains entirely unknown. Here, we aim to explore the cardiac functions of MSI2. We confirmed the presence of MSI2 in the adult mouse, rat heart, and neonatal rat cardiomyocytes. Furthermore, Msi2 was significantly enriched in the heart's cardiomyocyte fraction. Next, using RNA-seq data and isoform-specific PCR primers, we identified, Msi2 isoforms 1, 4, and 5 and two novel putative isoforms labeled as Msi2 isoforms 6 and 7 to be expressed in the heart. Overexpression of Msi2 isoforms led to cardiac hypertrophy in cultured cardiomyocytes. Additionally, Msi2 was also found to be significantly increased in a pressure-overload model of cardiac hypertrophy. To validate the hypertrophic effects, we selected isoforms 4 and 7 due to their unique alternative splicing patterns. AAV9-mediated overexpression of Msi2 isoforms 4 and 7 in murine hearts led to cardiac hypertrophy, dilation, heart failure, and eventually early death, confirming a pathological function for Msi2. Using global proteomics, gene ontology, transmission electron microscopy, and transmembrane potential measurement assays increased MSI2 was found to cause mitochondrial dysfunction in the heart. Mechanistically, we identified Cluh and Smyd1 as direct downstream targets of Msi2. Overexpression of Cluh or Smyd1 inhibited Msi2-induced hypertrophy and mitochondrial dysfunction in cardiomyocytes. Collectively, we show that Msi2 induces hypertrophy, mitochondrial dysfunction, and heart failure. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Guh leh tang nat na nop tuam na ding // Health talk.Kawikawi + Tang thu ngaih pen // Chin Gospel Songs.

Gil sung a ih thau te kiam na ding // Health talk.Kawikawi + It huai Topa // Chin Gospel Songs.

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.12.19.521052v1?rss=1 Authors: Mancini, N., Thoener, J., Tafani, E., Pauls, D., Mayseless, O., Strauch, M., Eichler, K., Champion, A., Kobler, O., Weber, D., Sen, E., Weiglein, A., Hartenstein, V., Thum, A. S., Rohwedder, A., Schleyer, M., Gerber, B. Abstract: Larvae of the fruit fly Drosophila melanogaster are a powerful study case for understanding the neural circuits underlying behavior. Indeed, the numerical simplicity of the larval brain has permitted the reconstruction of its synaptic connectome, and genetic tools for manipulating single, identified neurons allow neural circuit function to be investigated with relative ease and precision. We focus on one of the most complex neurons in the brain of the larva (of either sex), the GABAergic anterior paired lateral neuron (APL). Using behavioral and connectomic analyses, optogenetics, Ca2+ imaging and pharmacology, we study how APL affects associative olfactory memory. We first provide a detailed account of the structure, regional polarity, connectivity, and metamorphic development of APL, and further confirm that optogenetic activation of APL has an inhibiting effect on its main targets, the mushroom body Kenyon cells. All these findings are consistent with the previously identified function of APL in the sparsening of sensory representations. To our surprise, however, we found that optogenetically activating APL can also have a strong rewarding effect. Specifically, APL activation together with odor presentation establishes an odor-specific, appetitive, associative short-term memory, whereas naive olfactory behavior remains unaffected. An acute, systemic inhibition of dopamine synthesis as well as an ablation of the dopaminergic pPAM neurons impair reward learning through APL activation. Our findings provide a study case of complex circuit function in a numerically simple brain, and suggest a previously unrecognized capacity of central-brain GABAergic neurons to engage in dopaminergic reinforcement. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Tom's guest is a friend who recently began his second year as the Chief of Police in Sioux Falls. Jon Thum is a husband, a father and a follower of Christ who has devoted his life to serving the public through law enforcement.In this episode of The RESGEN Giving Life Podcast, Tom and Jon discuss how his faith influences how he leads the police department and ways that citizens can encourage local police officers. They also discuss what churches and individuals can do to help those who are coming out of prison and how he personally processes movements like ‘defund the police'.The Giving Life Podcast: Conversations about being a man whose life in Christ gives life to others.Watch the video version on youtube - youtu.be/8Uta32UKrkoMore info about Restoration Generation - www.resgen.org

Happy Monday! Nan tho tha hna maw? CEBC Podcast, Zumhtlak Saltha in Morning Devotion tuah ti dingin kan in sawm hna. A kan hruaitu: Rev. Dr. Van Bawi Kam Tlangtar: Minung Dir Hmun Phun Thum Nan zate Bawipa nih thluachuah in pe hna seh, Amen! CAPT, Zumhtlak Saltha. -- Music by Peder B. Helland

Vaney sat down with Sioux Falls Police Chief Jon Thum to talk community, work, and how the two tie together.

Happy Monday! Nan tho tha hna maw? CEBC Podcast, Zumhtlak Saltha in Morning Devotion tuah ti dingin kan in sawm hna. A kan hruaitu cu CEBC kan Pastor John Za Thleng a si i Pathian Sinak Phun Thum timi tlangtar in a si lai. Nan zate Bawipa nih thluachuah in pe hna seh, Amen! CAPT, Zumhtlak Saltha. -- Music by Peder B. Helland

In the study of 19th and 20th century Chinese history, there is often focus on the intense Christian missionary activities happening in China. Yet at the same time, members of China's Hui (or Sino-Muslim) community were also beginning to reconnect with their co-religionists overseas. Armed with knowledge of Arabic, Persian, and Urdu and trained in Western orientalist discourses in new religious schools overseas, these Hui scholars began to "rediscover" aspects of Islam and in the process rewrite the history of Islam in China both for audiences within China and for a non-Chinese audience overseas. In this episode, we are joined by Professor Nile Green of UCLA to talk about how and why these exchanges took place and some of the implications of these exchanges. Please also be sure to check out Professor Green's podcast "Akbar's Chamber" for monthly episodes on the history of Islam. Available on Apple Podcasts and all other major podcast platforms. Contributors Professor Nile Green Professor Nile Green is a Professor of History and the Ibn Khaldun Endowed Chair in World History at UCLA. He works on the Islamic history of Asia, the Middle East, Africa and Europe, publishing numerous monographs and articles and editing seven books on a wide range of topics related to the history of Islam. His recent research interest is on the global history of Islam and Muslims, focusing on intellectual and technological interchange between Asia and Europe; Muslim global travel writings; the transnational genealogy of Afghan modernism; and the world history of 'Islamic' printing. He was a founding director of UCLA's Program on Central Asia and serves on many association and editorial boards. He is also the host of Akbar's Chamber, a podcast that offers a non-political, non-sectarian and non-partisan space for exploring the past and present of Islam. Yiming Ha Yiming Ha is a Ph.D. candidate in the Department of History at the University of California, Los Angeles. His current research is on military mobilization and state-building in China between the thirteenth and seventeenth centuries, focusing on how military institutions changed over time, how the state responded to these changes, the disconnect between the center and localities, and the broader implications that the military had on the state. His project highlights in particular the role of the Mongol Yuan in introducing an alternative form of military mobilization that radically transformed the Chinese state. He is also interested in military history, nomadic history, comparative Eurasian state-building, and the history of maritime interactions in early modern East Asia. He received his BA from UCLA and his MPhil from the Hong Kong University of Science and Technology. Credits Episode no. 9 Release date: March 13, 2022 Recording location: Los Angeles, CA Bibliography courtesy of Professor Green Images Cover Image: Masjid at the Aligarh Muslim University (formerly Muhammadan Anglo-Oriental College) in Aligarh, Uttar Pradesh, India. It was founded by Sir Thomas Arnold and was (and still is) a major center of Islamic learning (Image Source). A view of the Darul Uloom Nadwatul Ulama in Lucknow, India, an Islamic seminary where Hai Weiliang* studied (Image Source). Sir Thomas Walker Arnold (1864-1930), a renowned British orientalist and Islamic scholar who wrote the famous The Preaching of Islam and The Encyclopedia of Islam. He founded the Muhammadan Anglo-Oriental College (now Aligarh Muslim University) and taught Syed Sulaiman Nadvi, who was the teacher of Hai Weiliang (Image Source). Syed Sulaiman Nadvi (1884-1953), the teacher and educational patron of Hai Weiliang (Image Source). * Sadly, no pictures of Hai Weiliang can be found. References Green, Nile. How Asia Found Herself: A Story of Intercultural Understanding. New Haven: Yale University Press, forthcoming 2022. Benite, Zvi Ben-Dor. The Dao of Muhammad: A Cultural History of Muslims in Late Imperial China. Cambridge, MA: Harvard University Asia Center, 2005. Benite, Zvi Ben-Dor. “Taking ʿAbduh to China: Chinese-Egyptian Intellectual Contact in the Early Twentieth Century.” In James Gelvin and Nile Green (eds.), Global Muslims in the Age of Steam and Print, edited by James Gelvin and Nile Green, 249-267. Berkeley: University of California Press, 2014. Chen, John. “‘Just Like Old Friends': The Significance of Southeast Asia to Modern Chinese Islam.” SOJOURN: Journal of Social Issues in Southeast Asia 31, no. 3 (2016): 685–742. Chen, John. “Islam's Loneliest Cosmopolitan: Badr al-Din Hai Weiliang, the Lucknow-Cairo Connection, and the Circumscription of Islamic Transnationalism.” ReOrient: The Journal of Critical Muslim Studies 3/2 (2018): 121-139.  Chung, Tan & Ravni Thakur (eds). Across the Himalayan Gap: An Indian Quest for Understanding China. New Delhi: Indira Gandhi National Centre for the Arts, 1998. Henning, Stefan. “God's Translator: Qu'ran Translation and the Struggle over a Written National Language in 1930s China.” Modern China 41, no. 6 (2015): 631-655. Jahn, Karl. China in der islamischen Geschichtsschreibung. Vienna: Österreichischen Akademie der Wissenschaften, 1971. Lipman, Jonathan N.  Familiar Strangers: A History of Muslims in Northwest China. Seattle: University of Washington Press, 1997. Mao, Yufeng. “A Muslim Vision for the Chinese Nation: Chinese Pilgrimage Missions to Mecca during World War II.” The Journal of Asian Studies 70, no. 2 (2011): 373–395. Murata, Sachiko. “The Muslim Appropriate of Confucian Thought in Eighteenth-Century China.” Comparative Islamic Studies 7, no. 1-2 (2012): 13–22. O'Sullivan, Michael. “Vernacular Capitalism and Intellectual History in a Gujarati Account of China, 1860–68.” The Journal of Asian Studies 80, no. 2 (2021): 267–292. Park, Hyunhee. Mapping the Chinese and Islamic Worlds: Cross-Cultural Exchange in Pre-Modern Asia. Cambridge: Cambridge University Press, 2012. Petersen, Kristian. Interpreting Islam in China: Pilgrimage, Scripture, and Language in the Han Kitab. Oxford: Oxford University Press, 2017. Sen, Tansen. India, China, and the World: A Connected History. Lanham: Rowman & Littlefield, 2017. Thum, Rian. The Sacred Routes of Uyghur History. Cambridge MA: Harvard University Press, 2014.

Dennis Thum is a husband, father, and grandfather, who has invested over 30 years of his life into the lives of thousands of college students as the campus pastor of the University of Sioux Falls.  On this episode of The Giving Life Podcast, Tom and Dennis discuss some of the most significant changes he has seen in college students over the last three decades, how men can wrestle with and figure out the role they are to play in God's Kingdom and what he is doing to finish strong in the race God called him to run. They also talk about a topic that the church doesn't deal with very well – divorce – and what he learned about himself, the Church and the Lord as he journeyed through his own experience with it.The Giving Life Podcast: Conversations about being a man whose life in Christ gives life to others.Watch the video version on youtube - youtu.be/1S6M20pCbe4 More info about Restoration Generation - www.resgen.org

God is taking us through a season where we need to be awake and we need to rise up in maturity. - Grow in maturity in the Word of God and in the power of the Holy Spirit. - Let's arise and seek God!

Make way for BIG Tracy and Rachel energy in this episode as they are completely honored and wildly enthused to be joined by Sioux Falls Police Chief Jon Thum. Chief Thum brings his signature character and integrity to the conversation as he discusses a worldview and a law enforcement approach that is both empathetic and respectful and one that seeks to restore dignity of all parties involved. Along the way he emphasizes the importance of bridge-building among the city's many communities, agencies, and leaders and commends Sioux Falls as being a leader in such collaboration. Tracy and Rachel learn that the road to becoming chief of police does not, in fact, involve the use of campaign yard signs, while Chief Thum reminds Rachel of their shared past in middle school youth ministry. While promoting Novem-burn, the city's fundraiser and awareness campaign for Operation Hope, Chief Thum acknowledges the timeless fashion influence of Beverly Hills 90210 on his own personal look and reveals the fateful day his signature sideburns were bested by his grandmother and a pair of clippers. He also explains how a past stint as the University of Sioux Falls Choir Chaplain led to a devotional about which light to follow, an anecdote that points back to his own decision to change course from an early career in business to pursue a calling to a life of service. Lastly, Chief Thum and Tracy feel kinship over their shared love of Mexican food and Rachel and Tracy unabashedly and, of course, enthusiastically invite Chief Thum back to a be a regular guest. Episode Mentions: Novem-burn for Hope Fundraiser: https://www.argusleader.com/story/news/2021/11/04/sioux-falls-police-chief-sideburns-fundraiser-novemburn-operation-hope-movember/6272739001/ Operation Hope: https://www.sfacf.org/news/operation-hope-fund-to-help-improve-continuum-of-care The Link: https://www.linksf.org/ Sioux Falls Police Department: https://www.siouxfalls.org/police Beverly Hills 90210 Sideburns: https://www.today.com/style/luke-perry-s-sideburns-are-part-what-made-him-star-t149807 Giliberto's Mexican Taco Shop: https://gilibertos.com Abelardo's Mexican Fresh: http://www.abelardosmexicanfood.com Azteca Family Restaurant: http://www.azteca-sd.com Jacky's Restaurant: http://www.jackysrestaurants.com Inca Authentic Mexican Restaurant: http://www.incamexicanrestaurantsf.com Morrie's Steakhouse: https://www.morriessteakhouse.com Chick-fil-A Sioux Falls: https://www.chick-fil-a.com/locations/sd/empire-place-sd

Dr. Carolyn Lam: Welcome to Circulation on the Run, your weekly podcast summary and backstage pass to the journal and its editors. I'm Dr. Carolyn Lam, associate editor from the National Heart Center and Duke National University of Singapore. Today we will be discussing the pooled analysis results of the 10 ODYSSEY Trials with important implications for the reduction of lipids in major cardiovascular events. But first, here's your summary of this week's journal. The first paper provides experimental data on vascular disease that brings into focus the critical roles of transcription factors such as GATA2 in the maintenance of endothelial cell function, as well as the role of selected microRNAs as a novel player of vascular regulation. In this study by first author Dr. Hartman, corresponding author Dr. Thum from Hanover Medical School, and colleagues, authors used GATA2 gain and loss of function experiments in human umbilical vein endothelial cells to identify a key role of GATA2 as a master regulator of multiple endothelial functions, and this via microRNA-dependent mechanisms. Global microRNA screening identified several GATA2-regulated microRNAs, including miR-126 and miR-221. GATA2 deficiency led to vascular abnormalities, whereas supplementation with miR-126 normalized vascular function. In a mouse model of carotid injury, GATA2 was reduced and systemic supplementation of miR-126-coupled nanoparticles enhanced miR-126 availability in the carotid artery and improved reendothelialization of injured carotid arteries in vivo. In summary, GATA2-mediated regulation of miR-126 and miR-221 has an important impact on endothelial biology. Thus, modulation of GATA2 and its targets miR-126 and miR-221 represents a promising therapeutic strategy for the treatment of vascular diseases. The next study is the first to show that current smokers from the general population have lower levels of circulating cardiac troponin I, a seemingly paradoxical observation given the known detrimental cardiovascular impact of cigarette smoking. First author Dr. Lyngbakken, corresponding author Dr. Omland, and colleagues from the University of Oslo used data from the large population-based HUNT study, in which cardiac troponin I was measured in 3,824 never smokers, 2,341 former smokers, and 2,550 current smokers. Current smokers had significantly lower levels of cardiac troponin I than never smokers and former smokers, an association that remains significant even after adjustment for potential confounders. The authors also found an association between increasing concentrations of troponin I and clinical endpoints, namely acute myocardial infarction, heart failure, and cardiovascular death in the total cohort. However, this association was attenuated in current smokers and was significantly weaker than in never or former smokers with a p for interaction of 0.003. The prognostic accuracy of troponin I as assessed by C-statistics was lower in current smokers than in never smokers. Troponin I provided no incremental prognostic information to the Framingham Cardiovascular Disease risk score in the current smokers. Together, these results suggest that mechanistic pathways other than those involving subclinical myocardial injury may be responsible for the cardiovascular risk associated with current smoking. Future studies are needed to determine whether a lower cardiac troponin I threshold should be considered for exclusion of myocardial infarction in smokers or whether prognostic tools other than measurement of cardiac troponins should be utilized when evaluating risk of future events in current smokers. The next study contributes to our understanding of cardiomyocyte signaling in response to ischemic injury. In the study by first author Dr. [Wool 00:05:04], corresponding author Dr. [Ju 00:05:04] from Tongji University School of Medicine in Shanghai, and colleagues, authors sought to understand the role of low-density lipoprotein receptor-related proteins 5 and 6 as well as beta-catenin signaling in the heart. They did this using conditional cardiomyocyte-specific knockout mice who had surgically induced myocardial infarction. They found that deletion of lipoprotein receptor-related proteins 5 and 6 promoted cardiac ischemic insults. Conversely, deficiency of beta-catenin, a downstream target, was beneficial in ischemic injury. Interestingly, although both insulin-like growth factor-binding protein 4 and Dickkopf-related protein 1 are secreted beta-catenin pathway inhibitors, the former protected the ischemic heart by inhibiting beta-catenin, whereas the latter enhanced the injury response mainly through inducing lipoprotein-related protein 5 and 6 endocytosis and degradation. These findings really add to our understanding of the beta-catenin signaling pathway in ischemic injury and suggests that new therapeutic strategies in ischemic heart disease may involve fine-tuning these signaling pathways. The next paper from the International Consortium of Vascular Registries is the first study allowing an assessment of variations in repair of abdominal aortic aneurysms in 11 countries over 3 continents represented by the Society of Vascular Surgery and European Society for Vascular Surgery. Dr. Beck from University of Alabama-Birmingham School of Medicine, and colleagues, looked at registry data for open and endovascular abdominal aortic aneurysm repair during 2010 to 2013, collected from 11 countries. These were Australia, Denmark, Hungary, Iceland, New Zealand, Norway, Sweden, Finland, Switzerland, Germany, and the United States. Among more than 51,000 patients, utilization of endovascular aortic repair for intact aneurysms varied from 28% in Hungary to 79% in the United States, and for ruptured aneurysms from 5% in Denmark to 52% in the United States. In addition to the between-country variations, significant variations were present between centers within each country in terms of endovascular aortic repair use and rate of small aneurysm repair. Countries that more frequently treated small aneurysms tended to use the endovascular approach more frequently. Octogenarians made up 23% of all patients, with a range of 12% in Hungary to 29% in Australia. In countries with a fee for service reimbursement systems, such as Australia, Germany, Switzerland, and the United States, the proportion of small aneurysms and octogenarians undergoing intact aneurysm repair was higher compared to countries with a population-based reimbursement model. In general, center-level variation within countries in the management of aneurysms was as important as variation between counties. Hence, this study shows that despite homogeneous guidelines from professional societies, there is significant variation in the management of abdominal aortic aneurysms, most notably for intact aneurysm diameter at repair, utilization of endovascular approaches, and the treatment of elderly patients. These findings suggest that there is an opportunity for further international harmonization of treatment algorithms for abdominal aortic aneurysms. This is discussed in an accompanying editorial entitled, Vascular Surgeons Leading the Way in Global Quality Improvement, by Dr. Fairman. The final paper from Dr. Gibson at Beth Israel Deaconess Medical Center and Harvard Medical School and colleagues, presents the results of the apoAI event reducing in ischemic syndromes I, or AEGIS-I, trial, which was a multicenter, randomized, doubleblind, placebo-controlled dose-ranging phase 2b trial of CSL112, which is an infusible, plasma-derived apoAI that has been studied in normal subjects and those with stable coronary artery disease, but now studied in the current study in patients with acute myocardial infarction. The trial showed that among patients with acute myocardial infarction, four weekly infusions of a reconstituted, infusible, human apoAI, CSL112, was associated with a dose-dependent elevation of circulating apoAI and cholesterol efflux capacity without adverse hepatic or renal outcomes. The potential benefit of CSL112 to reduce major adverse cardiovascular events will need to be assessed in an adequately powered phase 3 trial. Now for our future discussion. Today I am delighted to have with us Dr. Kausik Ray from Imperial College London, who's the first and corresponding author of a new paper regarding the pooled analysis of the 10 ODYSSEY Trials. To discuss it with us is Dr. Carol Watson, associate editor from UCLA. Kausik, just let me start by congratulating you on this paper. I believe this is the first data that allows us to look under the 50 mg/dL mark of LDL and really ask if the LDL MACE relationship extends below this level. Dr. Kausik Ray: Yes, the reason for looking at this is that the IMPROVE-IT trial really looked at people down to an average LDL cholesterol of about 54, and with the new PCSK9 inhibitors, which instead of giving you a 20% further reduction LDL, they give you the opportunity for a further 50 to 60% reduction. We actually get the chance to get people down to levels like 25 mg/dL, and the question is, does the benefit continue at that level? We did a pooled analysis of 10 of the ODYSSEY Trials, really in some ways to try and help predict what you might see in ODYSSEY outcomes, what you might see in the [Fuliay 00:12:00] trial, and to also manage expectations as well, because there's probably been a lot of hype around the two New England Journal papers about 50, 60% reductions of all potential reductions based on small numbers of events. So the question is, if you reduce LDL by 39 mg/dL, how might that reduce your risk, and is the relationship continuous? So those were the aims. Dr. Carolyn Lam: That's great, and maybe could you give us an idea of the number of patients you are looking at and the number of events? Dr. Kausik Ray: Yeah. In the 10 pool studies, we had just under 5,000 individuals, and we had just about 6,700 person years' worth of followup. In total, we had 104 first MACE events. To put this into context, it's about one third of the number of events that the first [framing 00:12:53] of analysis had. It's an observation analysis rather than randomized trial data, so you got to bear that in mind with the usual caveats that go with observational data. But the same endpoints that were adjudicated, this is [inaudible 00:13:10] heart disease death, non-fatal MI, ischemic stroke, and unstable angina requiring hospitalization. This is the same endpoint that is in the ODYSSEY Outcomes Trial, so it's interesting in that regard. Dr. Carolyn Lam: Yeah, it sure is. So what's the bottom line? What did you find? Dr. Kausik Ray: What we found was that there was a continuous relationship all the way down to LDL cholesterol levels of about 25 mg/dL, that every 39 mg/dL lower on treatment LDL, your risk went down by about 24%. If you looked at [apo-like 00:13:48] approaching be on non-HDL cholesterol, again, you found the same continuous relationship with a similar point estimate for a similar standardized difference in LDL cholesterol. We also looked at many of the guidelines, talk about percentage reduction. We actually looked at percentage reductions. If you start with a baseline LDL of X and you achieve a 50% further reduction in LDL, how much further benefit does that give you? A 50% further reduction gave you a 29% further lower risk of MACE. So we didn't find any threshold or limit all the way down to LDLs of about 25. Dr. Carolyn Lam: That's really a key, novel finding that you contributed, so congratulations once again. I suppose the question will always be, you're talking about relative risk reductions here. At such low levels, can you give us an idea of the absolute risk reductions? Dr. Kausik Ray: Yes. You've got to remember that the relative risk reductions are what you can apply to population differences. If you pick a high-risk patient population, you would expect to see a much bigger absolute risk reduction than maybe this study or another study. Similarly, if you pick a low-risk group, you are going to see a much smaller absolute benefit. I always try to advise a little bit of caution that if you basically look at the range ... If you start with let's say an LDL of 150 and you go down to let's say an LDL of 25, you are talking about a 1.25% absolute risk reduction. Remember, these patients are possibly going to be a slightly lower risk than the ones that are recruited into the ODYSSEY Outcomes and into the [Fuliay 00:15:46] trial, for example. Dr. Carolyn Lam: I think you mentioned what I was going to just ask you about. This is observational. You had 104 events, and I suppose another limitation might be that your followup was two years at max, if I'm not wrong? What do you say about that, and are there plans for future analyses? Dr. Kausik Ray: Within the context of these studies, I think that the whole of this data will eventually become dwarfed by what we see with the big CDOTs, because you've got 18, 27,000 people, 3 years' worth of exposure and followups, so you are going to have many, many more events. That is a limitation, but I think what is interesting is that we know that the baseline LDL cholesterol level is around about 90 mg/dL. We don't actually know what the actual baseline ... because the baseline [characters 00:16:43] haven't been published for ODYSSEY Outcomes, but the [Fuliays 00:16:46] around about 89. What it tells you is what the point estimate is likely to be. It's likely to be in the 24 to 32% ballpark because that's what your baseline LDL is and that's what we'd predict in the regression lines that we observed here. I think that we're not going to get many more events in these studies because largely the randomized period of followup is now over. Many of these people are now into open labels, extensions for safety, so we won't get many more events from this. In terms of, I think, the way people should maybe look at this is possibly as a taster for what's to come in the next 18 months or so. I think for the time being it answers two questions. Is lower likely to be better? And it is. I think the other question it tells is how might you get people down to LDLs below 50? One of the important things was that if you were just on statins, in this population, if you were recruited on the basis of a high baseline LDL, you got no additional people down to LDLs below 50. You got under 10% with add-on [inaudible 00:18:05], but you got around about 50% when you used the PCSK9 inhibitor as an add-on to existing therapy. It tells you about how to get to such low levels as well. I think that's the other key thing that it actually gives you. We did an analysis of safety [inaudible 00:18:23], and I think that's really important. Once you see the efficacy, or if you see the MACE events continue to go down ... If you looked at treatment-emergent adverse events ... and I completely take the fact that it's every side effect reported altogether, which may or may not be linked to LDL levels specifically, but when we did that, the relationship actually was just a horizontal line, so there was no relationship with percentage reduction or on treatment LDL, so it gave us a nice idea of both safety and efficacy that we might experience in the big outcome studies. Dr. Carolyn Lam: All right. Obviously the big outcome studies are going to be game changers, and I'd really love to invite [Carol Scotts 00:19:09] here, because there's a whole lot of other things that need to be considered if this becomes the case, isn't it? Carol, I really appreciated that you invited an editorial, and the editorial is by Neil Stone who entitles it, Looking Beyond Statins: Will the Dollars Make Cents? Please tell us about the discussions about this paper that occurred. Dr. Carol Lam: I would again like to congratulate Dr. Ray on a fantastic paper, and I would like to reiterate exactly what he said. I think it really does give us some comfort about this class of medication and its relative safety. I think that's very important, because I can't tell you how many patients I get and how many referring physicians I get who worry when their patients come back with LDLs of 20 or below. I think that gave us some comfort, and I do also think it was very important to show that this would fall along the same regression line that statins perhaps would fall. As with all the caveats that Dr. Ray said, I agree with all of them, but I do say this is a tasty little taster, and I appreciate and congratulate you for publishing this. The editorial by Dr. Neil Stone was quite interesting. As you said, he subtitled it, Will the Dollars Make Cents? C E N T S or S E N S E, sort of a play on words there. Will the relative benefits that we can achieve with this class of medications make sense for the cost of these drugs? That's obviously a very separate issue from what was discussed in the manuscript, but it's something to think about. We understand that there are additional patients that will be helped if they can get their LDL down, and we hope that that will translate into the outcomes. Again, just as Dr. Ray mentioned, we will have to wait for the cardiovascular outcomes trials to be completed. When they are, if they do show the benefits that we hope, will their price point make them accessible to enough patients for this to be a widely applied, utilized therapy? Or will they not? That's part of what was discussed in Dr. Stone's editorial. Dr. Kausik Ray: When we were writing the manuscript and stuff like that, and we were doing this and everybody's like, "Oh, wow, look at the graphs." I said, "Look, we need to balance all of these bits and reassure ... We've got an opportunity." So I suggested them giving those additional analyses, and you saw how big the online supplement was. There was a ton of work that we put into this, and to format it into a concise ... I really want to just thank the editorial board for giving us the chance and actually being able to help us and work with us on this, because it's really important. I hope people look at all of those things because it will help people also that question the LDL. They all talk about the hypothesis and the safety of really low LDLs, and people come off statins as a result. I think this will help. Dr. Carolyn Lam: You're listening to Circulation on the Run. Thank you so much for being with us, and don't forget to tune in next week.