Podcasts about improve it

Part Two.Erin Diehl dreamed of being the next Oprah but ended up becoming the queen of corporate improv instead. Now the founder and CEO of Improve It, she helps teams laugh their way to better performance. A self-declared “failfluencer,” Erin turns every faceplant into a feature. In this two-part series, we dig into her journey, her joy-first philosophy, and why bombing on stage—or in life—might be the best thing that ever happened to you.Key Highlights of Our Interview:WTF: Worst Terrifying Failure“2020 was my crash course in failure. The pandemic forced our in-person business to pivot entirely online overnight. At the same time, I juggled new motherhood, supporting a recovering parent, and trying to keep my business afloat. It was my WTF moment: my Worst Terrifying Failure.”This breakdown captures the essence of the MOVE ON methodology:1. Marinate: Sit With It, Not In ItFailure isn't something you can brush off overnight. Take the time to sit with your worst terrifying failure—your WTF story. Reflect deeply. Walk, journal, or simply allow yourself to process. It's about feeling without rushing to fix.2. Own It: Forgive and Face the Thought Worms“Own your part in the failure, but more importantly, forgive yourself. We repeat 80% of our negative thoughts daily, so break that cycle. Recognize those thought worms for what they are and stop letting them dictate your story.”3. Verify the Lessons: What Will You Take With You?“Failure comes bearing lessons—two or three takeaways that you can carry forward. Identify what you've learned and how you'll avoid the same pitfalls in the future. This step transforms failure into wisdom.”4. Evaluate: What's the Plan?5. Observe the Growth: Prepare for the Next Chapter6. Embrace Failure as Part of ChangeConnect with us:Host: Vince Chan | Guest: Erin Diehl --Chief Change Officer--Change Ambitiously. Outgrow Yourself.Open a World of Expansive Human Intelligencefor Transformation Gurus, Black Sheep,Unsung Visionaries & Bold Hearts.10 Million+ All-Time Downloads.Reaching 80+ Countries Daily.Global Top 3% Podcast.Top 10 US Business.Top 1 US Careers.>>>130,000+ are outgrowing. Act Today.

Part One.Erin Diehl dreamed of being the next Oprah but ended up becoming the queen of corporate improv instead. Now the founder and CEO of Improve It, she helps teams laugh their way to better performance. A self-declared “failfluencer,” Erin turns every faceplant into a feature. In this two-part series, we dig into her journey, her joy-first philosophy, and why bombing on stage—or in life—might be the best thing that ever happened to you.Key Highlights of Our Interview:Improv Meets the Corporate World“I didn't plan to merge improv and business. But during my nine-to-five at a recruiting firm, my nights were dedicated to stages at Second City and ImprovOlympic. Suddenly, I saw how listening, empathy, and quick thinking from improv transformed my work life. The dots connected.”United We Innovate“Pitching an improv workshop to United Airlines was a gamble, but it paid off—literally. What started as a passion experiment became a calling when United became my first paying client. Improv wasn't just for the stage anymore.”The Teacher's High“That feeling of guiding someone toward growth is intoxicating. It's a high I kept chasing, and the more I taught, the more I wanted to do it. Seeing others find joy became my own source of joy.”From ROI to ROO: The Objective Shift“We don't measure ROI; we measure ROO—Return on Objective. Every engagement starts with a consult call to pinpoint your specific challenges and objectives, ensuring everything aligns with the participants' needs.”Connect with us:Host: Vince Chan | Guest: Erin Diehl  --Chief Change Officer--Change Ambitiously. Outgrow Yourself.Open a World of Expansive Human Intelligencefor Transformation Gurus, Black Sheep,Unsung Visionaries & Bold Hearts.10 Million+ All-Time Downloads.Reaching 80+ Countries Daily.Global Top 3% Podcast.Top 10 US Business.Top 1 US Careers.>>>130,000+ are outgrowing. Act Today.

Part Two. Meet Erin Diehl, a woman who turned “winging it” into a career strategy. She's the founder and CEO of Improve It, a company that uses improv to help teams thrive. As a kid, Erin dreamed of being a talk show host. Instead, she became a top podcast host and business leader, blending humor and learning to help others grow. She calls herself a failfluencer—because, in her world, failure isn't an end, it's a punchline and a lesson. In this two-part series, we explore Erin's journey, her philosophy on joy, and why failing might just be your best career move yet. Key Highlights of Our Interview: WTF: Worst Terrifying Failure “2020 was my crash course in failure. The pandemic forced our in-person business to pivot entirely online overnight. At the same time, I juggled new motherhood, supporting a recovering parent, and trying to keep my business afloat. It was my WTF moment: my Worst Terrifying Failure.” This breakdown captures the essence of the MOVE ON methodology: 1. Marinate: Sit With It, Not In It Failure isn't something you can brush off overnight. Take the time to sit with your worst terrifying failure—your WTF story. Reflect deeply. Walk, journal, or simply allow yourself to process. It's about feeling without rushing to fix. 2. Own It: Forgive and Face the Thought Worms “Own your part in the failure, but more importantly, forgive yourself. We repeat 80% of our negative thoughts daily, so break that cycle. Recognize those thought worms for what they are and stop letting them dictate your story.” 3. Verify the Lessons: What Will You Take With You? “Failure comes bearing lessons—two or three takeaways that you can carry forward. Identify what you've learned and how you'll avoid the same pitfalls in the future. This step transforms failure into wisdom.” 4. Evaluate: What's the Plan? 5. Observe the Growth: Prepare for the Next Chapter 6. Embrace Failure as Part of Change Connect with us: Host: Vince Chan | Guest: Erin Diehl Chief Change Officer: Make Change Ambitiously. Experiential Human Intelligence for Growth Progressives Global Top 2.5% Podcast on Listen Notes World's #1 Career Podcast on Apple Top 1: US, CA, MX, IE, HU, AT, CH, FI 5 Million+ Downloads 80+ Countries

Part One. Meet Erin Diehl, a woman who turned “winging it” into a career strategy. She's the founder and CEO of Improve It, a company that uses improv to help teams thrive. As a kid, Erin dreamed of being a talk show host. Instead, she became a top podcast host and business leader, blending humor and learning to help others grow. She calls herself a failfluencer—because, in her world, failure isn't an end, it's a punchline and a lesson. In this two-part series, we explore Erin's journey, her philosophy on joy, and why failing might just be your best career move yet. Key Highlights of Our Interview: Improv Meets the Corporate World “I didn't plan to merge improv and business. But during my nine-to-five at a recruiting firm, my nights were dedicated to stages at Second City and ImprovOlympic. Suddenly, I saw how listening, empathy, and quick thinking from improv transformed my work life. The dots connected.” United We Innovate “Pitching an improv workshop to United Airlines was a gamble, but it paid off—literally. What started as a passion experiment became a calling when United became my first paying client. Improv wasn't just for the stage anymore.” The Teacher's High “That feeling of guiding someone toward growth is intoxicating. It's a high I kept chasing, and the more I taught, the more I wanted to do it. Seeing others find joy became my own source of joy.” From ROI to ROO: The Objective Shift “We don't measure ROI; we measure ROO—Return on Objective. Every engagement starts with a consult call to pinpoint your specific challenges and objectives, ensuring everything aligns with the participants' needs.” Connect with us: Host: Vince Chan | Guest: Erin Diehl Chief Change Officer: Make Change Ambitiously. Experiential Human Intelligence for Growth Progressives Global Top 2.5% Podcast on Listen Notes World's #1 Career Podcast on Apple Top 1: US, CA, MX, IE, HU, AT, CH, FI 5 Million+ Downloads 80+ Countries

Today, in anticipation of its second season, Asif and Ali discuss the hit Apple TV+ show ‘Severance' (1:49). They discuss the development of the show, creator Dan Erickson and producer/director Ben Stiller. After several tangents the guys go over the cast, including Adam Scott, the plot and the production design of the show. They give their overall thoughts on season 1 and then Asif discusses the first episode of season 2.    Then Ali asks Asif about memory (34:35). Asif talks about how memory is organized, the different types of memory and why forgetting is often due to a lack of attention. He then discusses different types of amnesia. After discussing why we make so many errors with our memory, Asif then discusses what we can do to improve our memory.  The opinions expressed are those of the hosts, and do not reflect those of any other organizations. This podcast and website represents the opinions of the hosts. The content here should not be taken as medical advice. The content here is for entertainment and informational purposes only, and because each person is so unique, please consult your healthcare professional for any medical questions.   Music courtesy of Wataboi and 8er41 from Pixabay   Contact us at doctorvcomedian@gmail.com   Follow us on Social media: Twitter: @doctorvcomedian Instagram: doctorvcomedian   Show Notes: Ben Stiller on ‘Severance,' Selling Out and Being Jewish Today: https://www.nytimes.com/2025/01/11/magazine/ben-stiller-interview.html The Hollywood Slog That Led Adam Scott to “Severance”: https://www.newyorker.com/magazine/2024/12/30/adam-scott-profile Adam Scott on the ‘innies' and ‘outies' of Severance Season 2: https://www.theglobeandmail.com/arts/television/article-adam-scott-on-the-innies-and-outies-of-severance-season-2/ How Memory Works and 6 Tips to Improve It: https://www.scientificamerican.com/article/how-memory-works-and-6-tips-to-improve-it/ Comic explainer: how memory works: https://theconversation.com/comic-explainer-how-memory-works-64485 Learning and memory: https://pmc.ncbi.nlm.nih.gov/articles/PMC4248571/ The Neuroscience of Memory: Implications for the Courtroom: https://pmc.ncbi.nlm.nih.gov/articles/PMC4183265/ Preventing Alzheimer's Disease: What Do We Know? https://www.nia.nih.gov/health/alzheimers-and-dementia/preventing-alzheimers-disease-what-do-we-know Alzheimer's prevention: Does it exist? https://www.mayoclinic.org/diseases-conditions/alzheimers-disease/expert-answers/alzheimers-prevention/faq-20058140 Memory: https://www.health.harvard.edu/topics/memory

You probably know this by now: I'm highly introverted.But in business, there are things I must do despite the fact that they don't come naturally. Speaking. Creating content. Networking. While, yes, sometimes these things can feel draining, they're essential to growing our businesses and building relationships.That's why I was so excited to sit down with Nick Gray, the mastermind behind hosting successful events and making meaningful connections. He's the author of The 2-Hour Cocktail Party and has built his career around bringing people together—even when it doesn't feel natural.In this episode, Nick shares tips that can make events and networking less overwhelming, especially for introverts like me.Click PLAY to hear all of this and…(00:00:00) How to host parties and network (even when you're an introvert.)(00:02:01) The struggles I face with mingling at events and feeling awkward in social settings.(00:04:42) Nick's advice on leaving events discreetly (AKA The Irish Exit.)(00:05:29) Doing this ONE thing helps introverts feel more comfortable at events and parties.00:08:52) How Nick grew his museum tour business.(00:11:59) How I REALLY felt hosting my team for a Christmas party.(00:14:26) Nick's brilliant advice about what to prioritize during a party or event.(00:16:11) What the best time to make a connection at a conference is.(00:32:40) Nick's tips on how to create connections as the host of an event.(00:37:08) The BEST way to make an introduction to someone.(00:40:40) An overview of Nick's business model and revenue streams.(00:46:09) Nick's storytelling techniques.(00:48:57) The significance of audience reactions during live events versus online content.(00:50:04) The complexities of sharing personal experiences with online audiences.(00:54:10) Nick's checklist of essential tasks to complete before hosting an event.For full show notes, visit jasminestar.com/podcast/episode501Listen to Related Episodes:How to Create More Meaningful Relationships in BusinessEmotional Intelligence in Leadership: How You Can Develop, Practice, and Improve It[9 min] Embracing Feedback to Grow Personally and ProfessionallyMentioned in this Episode:Nametags (Nick Recommended)

Did you know that you negotiate every single day—and not just in boardrooms or sales meetings? From discussing PTO with your boss to deciding dinner plans with your partner, negotiation is everywhere. But how often do we approach these conversations with strategy and confidence? In this episode of the Improve It! Podcast, Erin uncovers the secrets to navigating everyday negotiations with expert Kwame Christian. Kwame Christian is a renowned negotiation expert, speaker, and author, with years of experience helping individuals and organizations navigate difficult conversations with confidence. He is the Director of the American Negotiation Institute and the author of the acclaimed book Finding Confidence in Conflict. Here are 5 of our favorite takeaways from the conversation: 1. Negotiation Is Everywhere Kwame challenges listeners to recognize that negotiation happens far beyond formal boardroom settings. Whether asking for time off, resolving workplace conflicts, or navigating personal relationships, we negotiate daily. Becoming aware of these moments is the first step toward mastering them. P.S. - If you're interested in learning more about negotiation from top experts in the field, try this episode on for size: Episode 231: Ready to Negotiate Like a Pro in High-Stake Conversations? Tune in with FBI Insider Chris Voss 2. The Compassionate Curiosity Framework Kwame introduces a simple yet effective three-step method for approaching challenging conversations: 1.     Acknowledge and Validate Emotions: Lower emotional tension by recognizing the other person's feelings. 2.     Get Curious with Compassion: Ask open-ended questions to build trust and gather information. 3.     Joint Problem Solving: Collaborate to find mutually beneficial solutions. 3. Emotion Management is Key During the role-play, Kwame demonstrated how validating emotions helps de-escalate tension and fosters a more productive dialogue. For example, he acknowledged Erin's hypothetical frustrations about PTO limits, which set the stage for a constructive discussion. 4. Curiosity Builds Trust By asking open-ended questions with genuine curiosity, you gain valuable insights and strengthen relationships. Kwame's approach emphasized the importance of tone and empathy to keep conversations on track and uncover win-win opportunities. 5. Practice Makes Perfect Role-playing challenging scenarios, as Erin and Kwame did, is a practical way to build confidence and refine your negotiation skills. Kwame's advice? Push yourself to handle even the most unreasonable counterpart with calmness and clarity. Conclusion This episode is a masterclass in handling difficult conversations with grace and effectiveness. Kwame Christian's Compassionate Curiosity framework is a game-changer for anyone looking to improve their negotiation skills, whether at work or home. If you loved this episode and know someone who might benefit from it, please share it by copying the link and sending them a quick text/email. Sharing is caring!     No, You Hang Up First (Let's Keep Connecting) Did today's episode resonate with you? Leave us a review sharing your favorite insight from Kwame and we'll send you a free signed copy of I See You! A Leader's Guide to Energizing Your Team through Radical Empathy. Have another question that we can answer? Leave us a Speakpipe audio clip and we'll answer it in an upcoming episode. Don't want to miss another episode? If you're a Spotify listener, find our show here and click “Follow.” If you're an Apple Podcast listener, click here and make sure to hit “+Follow.” Want 2 emails a week from us? One with a quick tip you can implement right away to enhance your personal and/or professional lives & one of our famous F.A.I.L. Fourward Friday newsletters? Subscribe here.  Show Links Purchase I See You! A Leader's Guide to Energizing Your Team through Radical Empathy here and the Resource Guidebook that was built in conjunction with it here. Connect with Kwame Christian Kwame's company website Kwame's LinkedIn Kwame's podcast: Negotiate Anything Kwame's books: How to Have Difficult Conversations About Race: Practical Tools for Necessary Change in the Workplace and Beyond & Finding Confidence in Conflict: How to Negotiate Anything and Live Your Best Life  Connect with Erin Diehl x improve it! Erin's website Erin's Instagram Erin's LinkedIn improve it!'s website improve it!'s Instagram  

Part Two. Today's guest is Erin Diehl, founder and CEO of Improve It, a company that uses improv to help teams grow and thrive. Like me, she's also a top podcast host! From a young age, Erin dreamed of becoming a talk show host. Why did she choose that path? And how did her journey lead her to combine improv and business? I told Erin, “You're in the business of joy.” But beyond joy, we also talked about failure. Erin calls herself a “failfluencer”—a blend of failure and influence. This two-part series dives into her unique approach to joy, failure, growth, and learning. Key Highlights of Our Interview: WTF: Worst Terrifying Failure “2020 was my crash course in failure. The pandemic forced our in-person business to pivot entirely online overnight. At the same time, I juggled new motherhood, supporting a recovering parent, and trying to keep my business afloat. It was my WTF moment: my Worst Terrifying Failure.” This breakdown captures the essence of the MOVE ON methodology: 1. Marinate: Sit With It, Not In It Failure isn't something you can brush off overnight. Take the time to sit with your worst terrifying failure—your WTF story. Reflect deeply. Walk, journal, or simply allow yourself to process. It's about feeling without rushing to fix. 2. Own It: Forgive and Face the Thought Worms “Own your part in the failure, but more importantly, forgive yourself. We repeat 80% of our negative thoughts daily, so break that cycle. Recognize those thought worms for what they are and stop letting them dictate your story.” 3. Verify the Lessons: What Will You Take With You? “Failure comes bearing lessons—two or three takeaways that you can carry forward. Identify what you've learned and how you'll avoid the same pitfalls in the future. This step transforms failure into wisdom.” 4. Evaluate: What's the Plan? 5. Observe the Growth: Prepare for the Next Chapter 6. Embrace Failure as Part of Change Connect with us: Host: Vince Chan | Guest: Erin Diehl Chief Change Officer: Make Change Ambitiously. Experiential Human Intelligence for Growth Progressives Global Top 3% Podcast on Listen Notes World's #1 Career Podcast on Apple Top 1: US, CA, MX, IE, HU, AT, CH, FI, JP 2 Millions+ Downloads 50+ Countries

Part One. Today's guest is Erin Diehl, founder and CEO of Improve It, a company that uses improv to help teams grow and thrive. Like me, she's also a top podcast host! From a young age, Erin dreamed of becoming a talk show host. Why did she choose that path? And how did her journey lead her to combine improv and business? I told Erin, “You're in the business of joy.” But beyond joy, we also talked about failure. Erin calls herself a “failfluencer”—a blend of failure and influence. This two-part series dives into her unique approach to joy, failure, growth, and learning. Key Highlights of Our Interview: Improv Meets the Corporate World “I didn't plan to merge improv and business. But during my nine-to-five at a recruiting firm, my nights were dedicated to stages at Second City and ImprovOlympic. Suddenly, I saw how listening, empathy, and quick thinking from improv transformed my work life. The dots connected.” United We Innovate “Pitching an improv workshop to United Airlines was a gamble, but it paid off—literally. What started as a passion experiment became a calling when United became my first paying client. Improv wasn't just for the stage anymore.” The Teacher's High “That feeling of guiding someone toward growth is intoxicating. It's a high I kept chasing, and the more I taught, the more I wanted to do it. Seeing others find joy became my own source of joy.” From ROI to ROO: The Objective Shift “We don't measure ROI; we measure ROO—Return on Objective. Every engagement starts with a consult call to pinpoint your specific challenges and objectives, ensuring everything aligns with the participants' needs.” Connect with us: Host: Vince Chan | Guest: Erin Diehl Chief Change Officer: Make Change Ambitiously. Experiential Human Intelligence for Growth Progressives Global Top 3% Podcast on Listen Notes World's #1 Career Podcast on Apple Top 1: US, CA, MX, IE, HU, AT, CH, FI, JP 2 Millions+ Downloads 50+ Countries

https://youtu.be/sVFaWrHLtyw?si=zxAQk-XypEtl7qPA What's Right with You - 3 - Expert Level Success **WHAT'S RIGHT WITH YOU Bumper   Welcome to Redemption Church of Plano TX. My name is Chris Fluitt!   We are in the Good News Business.   What's right with you Not – What's wrong with you.   Last week we looked at Timmy's report card and decided to shift our focus from weakness to strength.   Today – Expert Level Success   Me: You know, for years I thought success was about being good at everything… Read self-help books Attend seminarsWatch every TED talk… Improve…   It was exhausting. I was spreading myself thin, trying to be a jack-of-all-trades… but a master of none.Lightbulb moment - I was so busy trying to be decent at everything, I wasn't giving myself the chance to be exceptional at anything.   It was like I was trying to play every instrument in the orchestra instead of mastering the one I was meant to play.   WE: I bet you can relate. We live in a world obsessed with success.   Social media bombards us with highlight reels of people's lives. We're constantly comparing ourselves, wondering why we're not as successful as the next person.   They are good at… cooking – I'll try to be like that.home keeping –  Style & fitness – Automotive repair – A decent man would be able fix up his car! Under-water basketweaving – I'd like to give that a shot. 77% of millennials (25 to 39-year-olds) 83% of Gen Z (16 to 24-year-olds) feel pressure to reach traditional life milestones earlier than previous generations.   This is the thought at work… I have to be good at all the things…I have to accomplish all the things…If I don't, I am unhappy, unfulfilled, a failure… It's exhausting! But what if I told you… The key to success isn't about fixing what's wrong with you, but maximizing what's right with you?   Success is not become better at all the things…Success is becoming an expert at the unique strengths God has invested in you.   GOD: Let's look at a success story from the Bible – Joseph.   JosephFancy Coat and Big Dreams   Son of Israel/Jacob Gift from his Dad - coat of many colors. Gift from God – Spiritual Dreams & AdministrationHis gifts did not make him popular with his brothers. In fact, it landed him in a pit and then sold into slavery.   Pit   God's plan for us is sometimes scary.   Joseph is sold into slavery to a man named Potiphar.   Pit -> Potiphar   God's gifting is still at work.Potiphar notices… and puts Joseph in charge of his household. (Genesis 39:4)   Administrative gifting. Manages the house.   BUT Potiphar's wife accuses Joseph of sexual assault- wrongfully by the way. Pit -> Potiphar -> Prison   God's plan for us is sometimes scary.   But God's gifting is still at work.   The warden of the Prison notices… puts Joseph in charge of managing the prison. (Genesis 39:22)   In the prison Joseph gets better at his gifts…He went from managing a household to managing an entire prison organization.He went from having dreams to interpreting the dreams of others. (The cupbearer and baker – Genesis 40)   No matter the hardship… his gifting causes Joseph to rise.   Your gifts still work in hard times   This is a hard time… what should I do?USE YOUR GIFTS!The economy is rough… what should I do? USE YOUR GIFTS!My new boss hates me… what should I do?USE YOUR GIFTS!I don't fit in at school… what should I do?USE YOUR GIFTS!   Use your gifts, and become an expert at your gift.   – Pharaoh has a dream. None of Pharaoh's wisemen and magicians can Genesis 41 interpret the dream…   The cupbearer says… I know a guy named Joseph. Joseph interprets Pharaoh's dreams. Not just give a vague interpretation; he provides a detailed analysis and a strategic plan.   This plan will cause… Pharaoh to grow to be the wealthiest person in the world. Solve a regional disaster of a famine. Save countless lives – including the lives of his brothers who threw him into a pit!   Joseph does not return to the prison…  

Understanding Fat Oxidation and How to Improve It for Endurance Athletes In this episode, we dive into the critical role of fat oxidation for endurance athletes and explore practical strategies to enhance it. We also feature insights from Dr. Dan Plews of ENDURE IQ, a renowned expert in sports science and endurance training. What is Fat Oxidation? Fat oxidation is the process by which the body breaks down fats for energy. For endurance athletes, improving fat oxidation is crucial as it allows the body to rely on fat for fuel during prolonged exercise, sparing glycogen and enhancing performance. Key Points on Improving Fat Oxidation: Train at the Right Intensity: Incorporate low-intensity sessions (zone 2 peak fat max) to improve fat utilization. Increase Mitochondrial Density: Regular aerobic training boosts the body's ability to oxidize fat by increasing mitochondria in muscle cells. Utilize Specific Fueling Strategies: Experiment with fat-based fuels like medium-chain triglycerides (MCTs) to promote fat metabolism during training. Periodization of Training: Combine high-intensity and low-intensity sessions to improve metabolic flexibility. Nutrition Adjustments: Focus on a balanced diet that promotes fat metabolism, with adequate healthy fats and nutrient-dense foods. Hydration and Electrolyte Balance: Maintain proper hydration and electrolyte levels to support metabolic functions, including fat oxidation. Monitor and Adjust: Use metabolic testing to track fat oxidation rates and adjust training and nutrition based on performance data. Dr. Dan Plews & ENDURE IQ's Approach to Fat Adaptation: Dr. Plews highlights the importance of structured training and nutrition strategies to optimize fat oxidation. The ENDURE IQ 101 course includes phases like: Fat Oxidation Base Training  Incorporating fat-burning intervals Fueling experiments  Monitoring performance with tools like metabolic testing By focusing on individualized approaches and periodized training, athletes can enhance fat oxidation, metabolic flexibility, and overall endurance performance. Mentioned in This Episode: Dr. Dan Plews, researcher and coach at ENDURE IQ ENDURE IQ 101 Course for improving fat oxidation and fat adaptation in endurance athletes Listen to the full episode for a deep dive into the science behind fat oxidation and actionable tips to fuel your next race!  Check out the YouTube Channel for many videos on how to fuel and train as an endurance athlete here.

August 30, 2024 / Mom &… Podcast Episode 142 / Guest: Erin Diehl Subscribe and Review wherever you listen to podcasts! Show Summary: In this episode of the Mom &… Podcast, hosts Missy Stevens and Susanne Kerns welcome guest Erin Diehl, founder of Improve It and author of I SEE YOU: A LEADER'S GUIDE TO... The post Laugh, Learn, Lead – Building Connection through Improv & Play appeared first on Mom And Podcast.

Imagine if 4-day work weeks didn't only occur when a holiday weekend rolls around. Beyond more free time, do shorter work weeks also create financial gain? Today's case study explores that question with Erin Diehl, founder of B2B professional development company, Improve It and best-selling author of “I see You! A Leader's Guide to Energize Your Team Through Radical Empathy.” After a life altering concussion last year, Erin knew she needed to prioritize her physical and mental health, which prompted her to research the logistics of working only 4 days per week. In October 2023, her company piloted this new structure for all internal staff for 90 days, creating benchmarks to help them determine if this trial had been a success. Now nearly a year later, they're still going strong with 4 day work weeks and have hit their end of quarter revenue goals for three straight quarters, seeing as large as a 77% growth in a single quarter. Here's the process Erin and her team used to successfully implement this. View the transcript for this episode at: https://otter.ai/u/z8Q-Ug-rJFly8kzcK5BKLxb-1Ag?utm_source=copy_url Connect with Erin: https://www.learntoimproveit.com/ https://www.itserindiehl.com/ IG: https://www.instagram.com/improveitco/ IG: https://www.instagram.com/itserindiehl/ improve it! Podcast: https://podcasts.apple.com/us/podcast/improve-it-podcast-professional-development-through/id1508450538 I See You! book: https://www.amazon.com/See-You-Leaders-Guide-Energizing-Radical-Empathy/dp/B0CDJDP2S1/ref=monarch_sidesheet_title Links mentioned in the episode: Erin's 4 day work week blog post: https://www.learntoimproveit.com/podcast-content/episode-240-how-has-the-four-day-work-week-reshaped-work-life-balance-and-productivity-for-our-team 'Shorter' Book: https://amzn.to/4groa1E 'Traction' Book: https://amzn.to/3R1x0aD Suneera Madhani's episode: https://link.chtbl.com/qCQA_e3b Iconic business leaders all have their own unique genius. Take this quick 10 question quiz to uncover your specific CEO style advantage: https://ellenyin.com/quiz If you enjoyed today's episode, please: Post a screenshot & key takeaway on your IG story and tag me @missellenyin & @cubicletoceo so we can repost you. Leave a positive review or rating at www.ratethispodcast.com/cubicletoceo Subscribe for new episodes every Monday. Join our C-Suite membership to get bonus episodes! Check out everything our members get at https://ellenyin.com/csuite Learn more about your ad choices. Visit megaphone.fm/adchoices

Don't miss out—sign up for the last 2024 Mind Body cohort today!_____ Make sure to support this podcast by heading over to Paleovalley.com/NwJ, and all discounts will automatically be applied to your order. _____Judy and her team explore the intricate connection between the mind, body, and nervous system regulation, highlighting how crucial this relationship is for healing from chronic illness and enhancing overall wellness. They share personal stories and explain how practices like HeartMath, breathwork, and mindfulness can significantly impact physical and emotional health. Make sure to listen to the full episode to learn more.If you're ready to take the next step in your healing journey, now is the perfect time to enroll in our Mind Body Program, as this is the last cohort of the year!We discuss the following:Overview of the mind-body teamShanna shares her healing journey through mindfulness and dietImportance of calming the nervous system for healingHow triggers affect our nervous system and overall healthCore wounds and their impact on healthHow the Mind Body program helps chronic illnessUnderstanding the placebo and nocebo effects on healingClosing remarks on the importance of nervous system regulation_____EPISODE RESOURCESNwJ Mind Body ProgramFREE Manage Stress and Find Mental Clarity ResourcePower of Thoughts video The Mind Body Connection video 80 Year Study Shares Best Secret for Health and How to Improve It video_____WEEKLY NEWSLETTER 

Dr. Laura welcomes special guest Erin Diehl to the show to talk about radical empathy and Erin's new book “I See You!: A Leader's Guide to Energizing Your Team Through Radical Empathy”. Erin Diehl is a Business Improv Edutainer, author, and keynote speaker who hosts the improve it! podcast. Dr. Laura and Erin talk about Erin's recent journey of self-exploration and why she was called to write her book after emerging from an oppressive hustle mentality.Erin understands how people get to a place of being overloaded, stressed, burnt out, and feeling like they don't matter. Her desire through the book and her work is to help people, including leaders, give to themselves and take moments of self-reflection. She shares her journey through struggles with infertility and the physical pain that came from overwork. Erin's story of how she decluttered her life, found her purpose, and claimed inner peace is inspiring. The revelations and discoveries in her book are for everyone to apply to their own lives, especially those in management positions so toxic leadership can be replaced by leaders who are empathetic and supportive.“And it's so crazy how our thoughts really affect every cell in our body. And I'll tell you this, I didn't heal, I had chronic back pain, like shoulder pain and back pain that was so tight... I would literally cry myself to sleep at night because I was just so frustrated. … I took every ergonomic chair on Amazon into my office. I tried all the things, all the pillows, and went to all the doctors. And no one could say what was wrong. And I finally realized it was just my own mental emotions and my own thoughts that were really stagnating me. And I had not dealt with a lot of things.” Erin DiehlAbout Erin Diehl:Erin “Big” Diehl is a Business Improv Edutainer, Failfluencer, and Professional Zoombie. Through a series of unrelated dares, Erin created improve it!, a unique professional development company that pushes others to laugh, learn, play, and grow. Among her many accolades, Erin is most proud of successfully coercing over 30,000 professionals to chicken dance.Erin Diehl is a graduate of Clemson University, and a former experiential marketing and recruiting professional as well as a veteran improviser from the top improvisational training programs in Chicago, including The Second City, i.O. Theater and The Annoyance Theatre.Erin has spoken on global stages both virtually and in person - with companies like Uber Freight, Walgreens, Motorola, LinkedIn and The Obama Foundation (to name a few)! She is a member of The Chicago Innovation Awards Women's Cohort and a graduate of the Goldman Sachs 10,000 Small Business Program. She is also the proud host of a Top 1% Global Podcast, The improve it! Podcast, which you can find anywhere you listen to pods!When she's not playing pretend or facilitating, she enjoys walking on the beach with her husband, son, and eight-pound toy poodle, BIGG DIEHL.Resources:Website: LearnToImproveIt.comThe improve it! PodcastErin Diehl on Instagram“I See You!: A Leader's Guide to Energizing Your Team Through Radical Empathy” by Erin DiehlMarie Kondo“When the Body Says No: The Cost of Hidden Stress” by Gabor Maté MDBestseller Masterclass with Gabby Bernstein“The Artist's Way” by Julia CameronLearn more about Dr. Laura on her website: https://drlaura.liveFor more resources, look into Dr. Laura's organizations: Canada Career CounsellingSynthesis Psychology

N Engl J Med 2015;372:2387-2397Background: Statins, inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, effectively lower low-density lipoprotein (LDL) and improve cardiovascular outcomes across different populations. High-intensity statins exhibit greater efficacy in lowering LDL and decreasing non-fatal cardiac events compared to moderate-intensity statins. Nonetheless, due to the residual risk of cardiac events, and concerns about the safety and tolerability of high intensity statins, there is a growing demand for newer therapeutic options.Cardiology Trial's Substack is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.Ezetimibe acts on the Niemann–Pick C1–like 1 (NPC1L1) protein, inhibiting cholesterol absorption from the intestine. When combined with statins, ezetimibe further decreases LDL levels by an average of 23 to 24%.The IMPROVE-IT trial sought to test the hypothesis that adding ezetimibe to simvastatin is superior to simvastatin alone in reducing cardiovascular events in patients with recent acute coronary syndrome.Patients: Patients were enrolled if they had acute coronary syndrome (STEMI, NSTEMI or high-risk unstable angina) in the preceding 10 days, and were at least 50 years old. LDL levels within 24 hours of the acute coronary syndrome (ACS) had to be at least 50 mg/dL but less than or equal to 125 mg/dL in lipid-therapy naïve patients or less than or equal to 100 mg/dL in patients receiving lipid lowering therapy. Patients were excluded if they had hemodynamic or electrical instability following the ACS event, planned CABG, active liver disease, creatinine clearance< 30 ml/min, or they had chronic lipid lowering therapy of simvastatin> 40mg, atorvastatin 40mg or more, any dose of rosuvastatin, or any ezetimibe/simvastatin combination.Baseline characteristics: The average age of patients was 64 years with 76% being men. The average weight was 83 kg. About 27% had diabetes, 61% had hypertension, 21% had prior myocardial infarction, 4% had congestive heart failure and 33% were current smokers. The median creatinine clearance was 85 ml/ min. The index event was STEMI in 29% of the patients, NSTEMI in 47% and unstable angina in the rest. Coronary angiogram was performed in 88% of the patients and percutaneous coronary intervention was performed in 70%. The mean LDL was 94 mg/dL and was similar in both groups.Procedures: Patients were randomized 1:1 in a double blinded fashion to receive simvastatin 40mg daily plus ezetimibe 10mg daily or simvastatin 40mg daily plus placebo. Patients had follow-up visits at 30 days, 4 months, and every 4 months thereafter.In both study groups, if LDL level was higher than 79 mg/dL on two consecutive measurements, the simvastatin dose was increased to 80 mg per day. This practice continued until June 2011, approximately one year after the study's randomization concluded, when the Food and Drug Administration advised limiting new prescriptions of simvastatin 80 mg daily. If LDL levels were higher than 100 mg/dL on the new regimen, the study drug could be discontinued, and more potent therapy could be initiated. Patients were followed for at least 2.5 years and for up to 7 years.Endpoints: The primary efficacy end point was a composite endpoint of death from cardiovascular disease, a major coronary event (defined as nonfatal myocardial infarction, unstable angina requiring hospital admission, or coronary revascularization occurring at least 30 days after randomization), or nonfatal stroke. The trial also reported death from any cause as part of one of the secondary composite endpoints. Safety variables included liver enzymes and creatine kinase levels, myopathy or rhabdomyolysis, gallbladder-related adverse events or cancer.Statistical analysis was performed based on the intention-to-treat principle. To achieve 90% power for detecting 9.375% lower relative risk for the primary end point with simvastatin–ezetimibe combination compared to simvastatin alone, an estimated sample size of 18,000 patients and 5,250 primary events was required.Results: The trial randomized 18,144 patients in 39 countries; 9067 randomized to the simvastatin–ezetimibe combination and 9077 to the simvastatin monotherapy group.The simvastatin–ezetimibe combination led to greater reduction in LDL. At 1 year, the mean LDL was 53 mg/dL in the simvastatin–ezetimibe combination group and 70 mg/dL in the simvastatin monotherapy group. The simvastatin dose was increased to 80mg per day in 6% of the patients in the simvastatin–ezetimibe group and 27% in the simvastatin monotherapy group.The use of simvastatin–ezetimibe led to greater reduction in the primary endpoint compared simvastatin monotherapy (32.7% vs 34.7%, HR: 0.94; 95% CI: 0.89 - 0.99; p= 0.016). This reduction in the composite primary endpoint was primarily driven by reduction in non-fatal myocardial infarction (12.8% vs 14.4%) as well as ischemic stroke (3.4% vs 4.1%). There was no significant difference in death from any cause (15.4% vs 15.3%) or death from cardiovascular causes (6.9% vs 6.8%).The benefits of simvastatin–ezetimibe were more pronounced in patients who were 75 years or older (39.0% vs 47.6%, HR 0.80, 95% CI: 0.70 - 0.90; p for interaction= 0.005) and in patients with diabetes (40.0% vs 45.5%, HR: 0.86, 95% CI: 0.78 - 0.94; p for interaction= 0.023).No significant differences in safety endpoints were observed between both groups. Elevation of liver enzymes 3 times or more the upper limited of normal occurred in 2.5% of the patients in the simvastatin–ezetimibe combination group and 2.3% in the simvastatin monotherapy group.Conclusion: In patients with recent acute coronary syndrome, the combination of simvastatin–ezetimibe as compared to simvastatin monotherapy improved the primary composite outcome of death from cardiovascular disease, major coronary events, or nonfatal stroke. This reduction was modest, about 6% relative reduction, and was primarily driven by reduction in non-fatal myocardial infarctions and ischemic strokes. The trial results supports the hypothesis that lower LDL levels improves outcomes regardless of how it's achieved. The trial has good interval validity but the external validity is limited in the current era because simvastatin is infrequently used nowadays with atorvastatin and rosuvastatin being the preferred agents. Patients taking atorvastatin 40mg or more and patients taken any dose of rosuvastatin at baseline were excluded from the trial. Furthermore, it's unclear why the trial did not permit the inclusion of patients whose LDL exceeded certain limits as only patients with mild elevation in LDL at baseline were permitted to be enrolled.This trial does not answer the question most physicians may encounter in their practice: What's the benefit of adding ezetimibe to high-intensity statins or prescribing it to patients with moderate or high elevation in LDL levels?Cardiology Trial's Substack is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. Get full access to Cardiology Trial's Substack at cardiologytrials.substack.com/subscribe

Authentic Health Friday-Body Composition: Impact on Healthspan and How to Improve It

Have you ever been struck by lightning—metaphorically speaking, of course? That's the jolt of inspiration you'll feel when you hear Erin, improv virtuoso and empathetic leadership guru, recount her leap from the corporate grind to the founder of her own company, Improve It. Our chat brims with laughter and sage advice, as we talk about why empathetic communication isn't just nice to have, but a critical skill across all levels of business—whether you're captaining a team, dealing with clients, or flying solo. Erin's journey through the improv world and her spontaneous spirit—best illustrated by her whimsical "The Price is Right" escapade—will leave you pondering the poignant connection between a zest for life and professional success. Find Erin Diehl Online:itserindiehl.com learntoimproveit.com @itserindiehl on InstagramErin Diehl on LinkedInPURCHASE HER BOOK, I SEE YOU: https://www.itserindiehl.com/i-see-you Find Lauren Loreto online:Follow us on Instagram: @brandgoodtime @shesbusyafConnect with Lauren on LinkedIn: www.linkedin.com/in/laurenloreto Timestamps:Erin's background (00:01:21) Personal anecdotes and the impact of childhood experiences (00:04:35)The impact of frequent relocations on personal growth (00:06:15) Erin's journey to creating Improve It (00:13:31) The significance of improv and overcoming fears (00:17:48) Radical Empathy as a Leader (00:22:02) Negative Listening Patterns and Empathy (00:27:31) Where to Find Erin's Book and Staying Connected (00:37:10)Topics Discussed: Lauren Loreto, podcast, She's Busy AF, Brand Good Time, content marketing, web development, Erin Diehl, business improv educator, Improve It, keynote speaker, empathetic leadership, professional development, comedy, experiential learning, background, experiences, insights, improv, personal growth, childhood experiences, challenges, adaptability, authenticity, community, college experience, Clemson University, aspirations, broadcast journalism, Chicago, Second City, Improve It, professional development company, acting classes, theater, leadership, radical empathy, book, communication skills, effective communication workshop, negative listening patterns, IQ, leader, burnout, recalibrate, healing journey.

Episode #88 featuring Erin Diehl, CEO of Improve It and host of the Improve It Podcast! Her company, Improve It, has aided everyone, from Fortune 500 companies to small mom-and-pop shops, in transforming their businesses, leadership, and personnel through play. With eighteen years of leadership experience and expertise in improvisational comedy, Erin instigates a mindset shift for busy, stressed-out leaders.Listen to James Ontra and Erin Diehl discuss how Improve It has been assisting businesses worldwide and discover how their help towards eliminating mental barriers can transform individuals into their best selves, both personally and professionally.This Podcast is sponsored by ShufflrrVisit www.Shufflrr.com for all things Presentation Management!

Empathy is hard. It requires deep courage, extreme emotional intelligence, maturity, and a commitment to learning and growing. Like most things, the best place to start is where your feet are. With your family, your friends, your colleagues, and your community. So, today, we're going to talk about how empathy impacts you at work, with your team – yes, as leaders, which most of us are whether or not our title says so – and also as members of a team. I've asked Erin Diehl to be our guest. Known as Erin “Big” Diehl, she's a Business Improv Edutainer, Failfluencer, and Professional Zoombie. Through a series of unrelated dares, Erin created Improve It!, a unique professional development company rooted in improv comedy, that pushes leaders and teams to laugh, learn, play, and grow. She is the proud host of The improve it! Podcast, a fellow Top 1% Global Podcast, and is the first time author of the Amazon Best Seller Top New Release: I See You! A Leader's Guide to Energizing Your Team Through Radical Empathy. Among her many accolades, and there are many, Erin is most proud of successfully coercing over 35,000 professionals to do the chicken dance. Empathy works best when it's a two-way street, for sure, but you are in charge of only one person's choices – and that's your own. As leaders, in business, in life, in our families and our communities – we have an opportunity to choose empathy. People learn best by experience and observation, so this is how we change our cultures, environments, and even the world. Connect with Erin: Website: www.itserindiehl.com  Book: I See You! Podcast: https://www.learntoimproveit.com/podcast LI: linkedin.com/in/erindiehl IG: @itserindiehl Like what you heard? Please rate and review  Thanks to our This Is Woman's Work Sponsor: To get the kids you love their very own Zenimal head to zenimals.com/NICOLEMKALIL and use my code NICOLEMKALIL to save 10% off!  

Zehra Mahoon is a former financial advisor turned master mindset and law of attraction coach. She is the author of twelve books on the subject and the creator of the Unlimited 40-day Law of Attraction Workout. After committing to completely transforming her self-worth in 2006, she went from being massively in debt to owning multiple properties and creating a thriving business, as well as healing her relationships. In this interview, Zehra discusses her book on abundance, “The Prosperity Puzzle: Your Relationship with Money and How to Improve It.” Connect with Zehrahttps://www.zmahoon.com/Facebook: Zehra Mahoon Instagram: @zmahoon Book: The Prosperity Puzzle: Your Relationship with Money and How to Improve ItSupport the showCONNECT WITH RHONDA RYDERFREE Guided Visualization on Abundance with Rhonda RyderIt includes six of my top episodes on prosperity. https://deliciousalignment.com/abundance/FREE Love Your Body Online Course 20+ Videos based on my five steps to loving your body and making peace with food.https://deliciousalignment.com/freecourse Delicious Alignment Facebook Grouphttps://www.facebook.com/groups/deliciousalignmentInstagram@deliciousalignmentThe BookDelicious Alignment: How 25 Women Learned to Love and Transform Their Bodies Using Abraham-Hicks and the Law of Attractionhttps://amzn.to/3fkTDoyPrivate Coaching with Rhondahttps://deliciousalignment.com/coaching/Websitehttps://deliciousalignment.comPodcast Advertising InquiriesContact us at support@deliciousalignment.comSupport the Showhttps://paypal.me/deliciousalignment

(REPLAY) Learn Speak Teach Episode #21. Leadership skills are like muscles- they must be developed and exercised continuously. To stay in shape, you need to push yourself past your comfort zone and take on new challenges. They include things like communication, empathy, listening, decision-making, and managing change. Some people think leadership is about being in charge and others think it's about being a good listener. But there are many different ways of leading your team towards success and achieving your goals, so make sure you know what works for you and your team by tuning to this episode with Erin Diehl! Erin is a Business Improv Edutainer, Failfluencer, and Professional Zoombie who is ready to help you “IMPROVE IT.” Her mission in life is to help you develop teams and leaders through play, improv, and experiential learning. Erin has helped everyone from Fortune 500 companies to small mom and pop shops transform their business, leadership, and people through play! Tune in! During this episode, you will learn about; [03:06] Introduction to the show. Why you should add Truffle Salt to your cart Now!! [06:50] Meet today's guest, Erin Diehl [07:50] How Erin became a ‘Failfluencer.' [10:55] How Erin saw the Covid pandemic as an opportunity rather than a setback [13:37] The post-covid goodies that Erin could not get without the pandemic [15:58] How you can take Erin's workshops [17:40] One of the ten power skills Erin teaches at the workshop [23:02] Why she refers to herself as a Professional ‘ZOOMbie.' [23:43] Why you should embrace the suck after disappointments [31:12] How her infertility struggles led her to meditation and mindfulness [33:32] Erin's mindfulness meditation routine you can copy [36:12] Rapid Fire Round [45:54] Where you can get Erin's podcast [46:50] Chicken dance Notable Quotes ~ “Your successes and your failures are both equal breaks in the foundation that you are building. You won't always succeed at everything, but you won't always fail, either. Each setback or victory is an important building block for your future success.” ~ “Having an occasional setback can be a real blessing in disguise. When you need to cancel plans or embrace your emotions, don't forget that it takes time to grow stronger and smarter. Embrace the suck, it takes time to overcome your disappointments.” ~ “Before you can help others, you need to know how to help yourself first. You have to fill the kettle up before you start sharing, but you cannot fill the kettle if there's nothing to fill it.” Keep In Touch with Erin Diehl: Website: www.learntoimproveit.com/ LinkedIn: www.linkedin.com/in/erindiehl/ Instagram: www.instagram.com/keepinitrealdiehl/ Podcast: www.learntoimproveit.com/podcast Website: www.realbusinessconnections.com/ — Follow Balbert… Facebook www.facebook.com/balbertmarketing Instagram: www.instagram.com/realbenalbert/ LinkedIn: www.linkedin.com/in/ben-albert-a74737106/ – LST is made possible by www://balbertmarketing.com/

SHOW NOTES: On this show…we're going to coast down the decline while we gain momentum for the upcoming hills, pushing it one more mile at a time. Sometimes, quitting is not an option but how do you find prevailing perseverance when your tank is empty? One moment at a time, that's how. Even when you think you've come to the end of your road and have hit a dead end, you have more to give than you think is humanly possible. But always pushing past your limits is not the goal. In everything, personal and professional, we are striving for a healthy balance. The word balance may just be a word you've heard but you're not really sure how it fits into your life…like the words self-care or relaxation. You might think those words are only entertained when everything else is done. That my friend would be the opposite of balance, imbalance.  So let's dig in to these ideas of perseverance, balance, and filling your tank. I love to be busy. I have an expanded capacity to take on more, juggle multiple things, and get things done. I hear it over and over from people who observe my life “Wow, how could you possibly take on one more thing”, “Where do you find the time”, “Do you ever sit down?”. I also don't recognize when I'm overwhelmed until I'm in crisis mode. Everyone deals with those feelings in different ways. You might scream, having feelings of anxiety, be nervous, and worry….I shut it out and do nothing. Haha the good thing is I don't stew over it or worry. The con is, I'm not getting it done because I switch to cruise control and sit back and relax. So knowing this about myself, I try and stay in that balanced state where I'm busy but not overwhelmed. Remember when Scarlet Ohara said, “I won't think about that today, I'll think about that tomorrow.” Yep, that's overwhelmed for me. What about you? Silvia shares 3 Reasons Why Perseverance is So Important (and 6 Ways to Improve It) found at trackinghappiness.com Karen Nimmo helps us with 7 Things to Do When Your Tank Is Empty Found at medium.com Over at medium.com I also found some great insight on Giving & Receiving: Finding The Right Balance CHALLENGE: one more mile, one more try, one more time. You have more effort available than you've recognized. Prevailing perseverance will propel you to navigate any challenge, delivering valuable learning along the way.    I Know YOU Can Do It!

This week, please join authors Marc Sabatine and Prakriti Gaba, as well as Associate Editor Amit Khera, as they discuss the article "Association Between Achieved Low-Density Lipoprotein Cholesterol Levels and Long-Term Cardiovascular and Safety Outcomes: An Analysis of FOURIER-OLE." Dr Greg Hundley: Welcome listeners, to this April 18th issue of Circulation on the Run and I am Dr. Greg Hundley, Associate Editor, Director of the Pauley Heart Center at VCU Health in Richmond, Virginia. Dr Peder Myhre: And I'm Dr. Peder Myhre, Social Media Editor from Akershus University Hospital and University of Oslo. Dr Greg Hundley: Peder, today's feature discussion, very interesting. We're going to evaluate the association between what's achieved with LDL cholesterol lowering, and then also long-term cardiovascular and safety outcomes. But before we get to that, how about we grab a cup of coffee and discuss some of the other articles in the issue? Would you like to go first? Dr Peder Myhre: Yes, Greg. I would love to. And the first paper is from the World of Preclinical Science and it comes to us from corresponding author, Jan Magnus Aronsen from University of Oslo in Norway. And perhaps, as you know, Greg, cardiomyocyte contraction and relaxation depend on the activity of the sarcoplasmic reticulum CA+2 ATPase 2, abbreviated SERCA2, and lowered levels or reduced activity of SERCA2, as seen in chronic heart failure, weakens contractile force and delays relaxation and no available therapy involves direct manipulation of the SERCA2 activity. And Greg, phosphodiesterase 3A is proposed to be present in the SERCA2 interactome limit SERCA2 activity and disruption of phosphodiesterase 3A from SERCA2 might thus be a strategy to develop SERCA2 activators. And in this study, the authors investigated and mapped SERCA2 and phosphodiesterase 3A and assessed this in experiments assessing the binding between these two in cardiomyocytes and in vesicles. Dr Greg Hundley: Wow Peder, sounds very interesting. So what did they find and how about the clinical implications of the findings? Dr Peder Myhre: So Greg phosphodiesterase 3A bounded directly to SERCA2 in the cardiomyocyte. So that's the first finding. Second, they demonstrated that SERCA2 phosphodiesterase 3A disruption increased SERCA2 activity independently of the catalytic activity of phosphodiesterase 3A in both normal and failing cardiomyocytes. And third, SERCA2 activity by the optimized SERCA2 phosphodiesterase 3A disruptor peptide OPT F reduced mortality and improved contractility after aortic binding in mice. So the clinical implication is that direct targeting of phosphodiesterase 3A binding to SERCA2 could be a novel approach to increase SERCA2 activity and thus cardiac contractility in patients with heart failure. Dr Greg Hundley: Very nice Peder. What a great new finding in the world of preclinical science. Well my paper is going to delve into the world of clinical science and involves patients with stroke. So Peder in this study led by corresponding author, Dr. Dileep Yavagal from University of Miami Miller School of Medicine performed a survey in 75 countries through the Mission Thrombectomy 2020+ Global Network between November of 2020 and February of 2021 to determine the availability of mechanical thrombectomy for large vessel occlusion in patients with stroke. Now Peder, the primary endpoints were the current annual mechanical thrombectomy availability, the mechanical thrombectomy operator availability and the mechanical thrombectomy center availability. All of these availabilities were defined as the proportion of estimated large vessel occlusion for patients receiving mechanical thrombectomy in a given region annually. Dr Peder Myhre: Okay, Greg, so this is really an access question. So in essence, what is the availability of mechanical thrombectomy worldwide? So what did they find? Dr Greg Hundley: Right, great Peder. So what they found, the authors received 887 responses from 67 countries and low-income countries had 88% lower mechanical thrombectomy availability compared to high-income countries. The global mechanical thrombectomy operator availability was 16.5% of optimal, and the mechanical thrombectomy center availability was only 20.8% optimal. And with these results, the authors indicate that global cooperation and targeted region-specific public health interventions, including all stakeholders involved in stroke care delivery, are really needed to rapidly increase access to this brain-saving and disability-sparing treatment with mechanical thrombectomy really worldwide. Dr Peder Myhre: Oh wow. What a beautiful summary, Greg. Thank you so much. And we also have some other interesting papers in the mailbag today. We have an exchange of letters between Dr. Yang and Dr. O'Donoghue regarding the article “Long Term evolocumab in Patients with Established Atherosclerotic Cardiovascular Disease.” Dr Greg Hundley: Great Peder, and also Professor Perera has a Frontiers article entitled “Unloading the Left Ventricle in Venoarterial ECMO in Who, When and How?” and then finally there's a Research Letter from Professor Verma entitled “Prevalence of Diabetes and Cardiovascular Risk in the Middle East and Africa: The Primary results of the PACT-MEA Study.” Well Peder, how about we jump to that feature discussion? Dr Peder Myhre: Can't wait. Dr Greg Hundley: Welcome listeners to this feature discussion on April 18th and we have with us today Prakriti Gaba and Marc Sabatine from Brigham and Women's Hospital and our own associate editor, Dr. Amit Khera. Welcome everyone. Well Marc, we'll start with you. Can you describe for us some of the background information that really helps constitute the preparation of your study and what was the hypothesis that you wanted to address? Dr. Marc Sabatine: Yeah, thanks Greg and thanks for having us. So we've seen in a variety of epidemiologic cohorts the association between LDL cholesterol and the risk of adverse cardiovascular events like in Framingham Heart Study and UK Biobank. But in those cohorts, in these industrial societies, we don't have the benefit of lots of data in individuals with very low levels of LDL cholesterol and so we had the opportunity with the FOURIER study that was the randomized comparison of evolocumab PCSK9 inhibitor versus placebo to get patients down to extremely low levels of LDL cholesterol and evolocumab. We were able to get individuals down to about 30 mg/dL. And so in addition to all the studies we've done showing the comparison of evolocumab to placebo, we also then had the chance to use FOURIER, and as you'll hear from PK, FOURIER-OLE, the open-label extension, as a cohort to then examine patients' new baseline, if you will, their new achieved LDL cholesterol and then it's association not only with cardiovascular events but safety events. And so the hypothesis is that there would be a relationship with the lower the LDL cholesterol, the lower the risk of cardiovascular events and we wanted to explore how far down that went. And then the second one for safety would be that there wouldn't be any association between low levels of LDL cholesterol and a variety of safety outcomes that rightly or wrongly people have ascribed to low levels of LDL cholesterol. Dr Greg Hundley: Thanks so much, Marc. Well listeners, now we're going to turn to PK, the first author, on this very interesting paper and PK, Marc mentioned to us the FOURIER-OLE study. Maybe describe for us here your study design and then what specifically was your study population? Dr. Prakriti Gaba (PK): Yeah, definitely. Thanks so much for the introduction. So the study population included 27,564 patients with stable atherosclerotic cardiovascular disease and LDL cholesterol levels that were greater than or equal to 70 mg/dL or non-HDL cholesterol greater than or equal to a 100 mg/dL on statin therapy. The patients who then went on to the FOURIER-OLE or the open-label extension part of the trial consisted of about 6,635 patients. And so in this study we essentially evaluated the combination of those populations in 2 separate analyses. We then categorized patients according to 6 pre-specified bins based on their achieved LDL cholesterol levels at designated time points and those ranged from LDL levels of less than 20 mg/dL all the way up to 100 mg/dL. And then we looked at their baseline characteristics and evaluated the cardiovascular and safety outcomes that Dr. Sabatine mentioned earlier. Dr Greg Hundley: Very nice PK. Well we've got a great listening audience today and they're anxious to hear your study results, so can you share those with us please? Dr. Prakriti Gaba (PK): Definitely. So over the course of more than 77,000 patient years of follow-up, we found that there was a monotonic relationship between achieving lower LDL cholesterol levels down to very low levels of less than 20 mg/dL and a lower annualized risk of the primary efficacy endpoint, which was a composite of 5 individual endpoints. We also found that there was a similar relationship observed between lower LDL achieved, LDL cholesterol levels and a lower annualized risk of the secondary efficacy endpoint, and then when we looked at safety, there were actually no clear monotonic trends between lower achieved LDL levels and the risk of any of the 8 adverse events and these included things like serious adverse events, hemorrhagic stroke or muscle related events. Dr Greg Hundley: Very nice PK and I'm sure our listeners are wanting to know, did you find any discrepancy in your results based on either age or gender? Dr. Prakriti Gaba (PK): That's an excellent question, and we did look at age and gender throughout. I think across the board the results were pretty consistent, but additional subanalyses will further address this question. Dr Greg Hundley: Very good. Well listeners now we're going to turn to one of our associate editors, Dr. Amit Khera, who has helped move this article through the process of evaluation with the editorial team. Amit, you have many papers come across your desk, what attracted you to this paper and then how do we put this study's results really in the context of other studies that have sought to dramatically lower LDL cholesterol? Dr. Amit Khera: Well first thanks a lot Greg for allowing me to participate today. I want to congratulate Drs. Gaba and Sabatine on a fantastic paper and the minute I saw it, and you know can tell when you've done this for a while what's a great paper, and this one certainly is and we work closely with them to try to make it better and enhance the analyses and as a group, I think we achieved that. I was fortunate to write an accompanying editorial that you'll see. So I got to take a pretty deep dive in this paper and I want to just talk about sort of what's important here, why is this important, and I think as Dr. Gaba mentioned, there's two sides to this. There's the efficacy side where you talk about LDL lowering and getting to very low levels. Now mind you, they got to, what I call, ultra low levels, even explored for a down to a median of 7 mg/dL, so really, really low. And first I think what our listeners need to know when we look at guidelines, these numbers of 70 or 55, these are completely arbitrary and they're based on what was observed in clinical trials, what was achieved in high intensity versus moderate intensity statins in IMPROVE-IT. There's no biology behind that, and I think what this study does is reminds us there is no biology behind how low we need to go. This group previously published their shorter-term data approximately 2 years with this construct of lower is better and I think that's fine, but people worry, particularly on the safety side about extension, and we'll get to that in a minute, so where this fits is it gives us even more reassurance that lower is better, reminds us there's no biologic basis of that even down to very low levels. And so what does that mean? I think that comes back to guidelines. We have some discrepancy between European, ACC, Multisociety Guidelines that are around 55 and so from a guideline perspective, I think we'll see a little bit more enthusiasm about lower cut points or lower thresholds. And from a clinical standpoint, as a clinician it reminds me that when I see someone that's very high risk, there's no magic to achieving a number that if the risk is high, we need to be quite intensive and get their LDL down as low as possible and as safely as possible. I do want to also acknowledge, there's not, to your point about context, the IMPROVE-IT study also showed very low levels show additional efficacy and there's also a lot of other data, genetics and ecologic data supporting this. So this is... we look at Bayesian analysis that this is consistent that we're seeing across different platforms. I do want to talk about safety too, Greg. That's really important because honestly this is when it comes to patient level, the safety part of it. We as clinicians may have comfort with very low levels, but the safety is important. I also want to, just from a steady design, this is post-hoc, so those that achieve very low levels are different. You can see that in their table 1, but these investigators did lots of things. They did pretty extensive multi-variable analysis, they looked at time-dependent LDLs, they looked at it multiple different ways, but as mentioned, there really did not seem to be a safety signal. And this is where time matters. Safety in two years, interesting, but safety 5 to 8 years really offers us much more reassurance. So I think that's where this really comes in about that safety piece with the extended analysis. So again, I think from a guideline perspective, from a clinical perspective, there's so many implications from this paper and I really hope people take the time to take a deep dive and also put it in context, like you said, to the other literature where this is not standalone, but it's corroborating what we're seeing. Dr Greg Hundley: Very nice, amit. Marc, I want to come back to you, just two quick questions thinking about the preparation of your study. One, did you sample cognition? One thing we hear about frequently in dramatic lowering of LDL cholesterol are questions around cognition, particularly in the elderly? Dr. Marc Sabatine: Yeah, it's a great question Greg. So first of all, in the FOURIER study itself, there was an embedded study called EBBINGHAUS that Bob Giugliano from our group led that actually did formal neurocognitive testing in individuals using basically a iPad-like test. We also collected the usual neurocognitive adverse events as part of safety collecting. So 2 ways, the general asking about any adverse events and then the specific neurocognitive testing. We had previously reported out the results of EBBINGHAUS that there wasn't any relationship between evolocumab and the low LDL cholesterol and the risk of any neurocognitive AEs. We just were able to recently do this OLE analysis over time for the major adverse cardiovascular events and for the general safety events including cognition, so all that looked good. As PK indicated, we're now digging into the EBBINGHAUS formal neurocognitive testing, which was also extended out. So stay tuned for those results. Dr Greg Hundley: Very nice. And then eligibility, maybe just walk us through that really quickly. Patients that are going to be randomized to this form of therapy, were they already on high-dose statins? Who exactly did we randomize in this trial? Dr. Marc Sabatine: Yeah, so at the get-go, as PK indicated, these are patients with atherosclerotic cardiovascular disease, so they had a prior MI, prior stroke, symptomatic PAD. They were to be on an optimized lipid-lowering regimen, optimized statin therapy, so for close to 70%, that was a high-intensity statin. We had a small percentage on ezetimibe, but that's because we hadn't yet published the results of the IMPROVE-IT trial that Amit mentioned when we were enrolling in FOURIER, but it was a well-treated population on statin therapy. So these results would apply to your typical patient with ASCVD who's on a good statin regimen. Dr Greg Hundley: Very nice. Well, listeners now we're going to go back to both of our authors and investigators, as well as Dr. Khera. PK we'll start with you. What do you see as the next study to really be performed in this sphere of research? Dr. Prakriti Gaba (PK): I think that's an excellent question. I think with the data presented here now we know that the lower the LDL, the lower the risk of adverse cardiovascular events and that having a low LDL is safe in the long term. I think moving forward, as Dr. Khera mentioned, there needs to be a shift of these recommendations into the guidelines. So I think additional studies confirming these findings is what we need, but we do have the evidence available. Dr Greg Hundley: Very nice. And Marc? Dr. Marc Sabatine: Yeah, and I agree with PK of course. I think there's a couple things that we want to look at. We had looked in the parent FOURIER trial and found some groups who were higher risk, who seemed to have a bigger benefit early on, and those by and large were people who had a lot of athero. But as Amit indicated that the parent FOURIER trial was relatively short at about in two and a quarter years median follow up, and so now we have the benefit of an additional half decade of follow up in a subset of people and so now we're starting to look through and see the subgroups where we saw some differential benefit and this was a paper we published in circulation soon after we published the primary results of FOURIER. Now we have the ability to go through and look at those same subgroups and see what happens now with an additional 5 years. And so that'll be quite interesting, I think, to see how those groups play out now over time. I think as Amit indicated, time is critical. We know the benefit of lipid lowering really tends to grow with time. We saw that in FOURIER, we saw that in FOURIER-OLE and then as Amit indicated, I think for safety also it's now very reassuring, being able to go out to not two and a half years, but 5, 6, 7, 8 years of safety follow up. Dr Greg Hundley: Very nice. Well, listeners we're next going to turn to Dr. Khera. I'm going to put him on the spot a little bit. I don't know if many of you know he's a cardiologist with expertise in primary prevention. So here we've really focused today, I think, on a very unique set of results in secondary prevention. Amit, as you think about studies to be performed in the future, is there a role for really lowering LDL cholesterol as a primary prevention target? Dr. Amit Khera: The short answer is absolutely. I think, to be fair, you can't necessarily directly extrapolate these results 'cause it's a secondary prevention population, but I think if we step back for a second, is there any reason I think this wouldn't work in primary prevention, there's not, and I think there's tons of genetic data, tons of other long-term data that suggests that lower is better than primary prevention. I think the challenge, as you know, is just from primary prevention is it's just about the number that you need to treat and primary prevention is pretty profound in terms of to lower events. So this is where the trade-off comes. I think even in their study, we do have to appreciate while lower is better, when you have very low levels and you're going to even lower, let's say when you go from in secondary prevention from 50 to 40, as much as that sounds valuable, that delta's pretty small and then the absolute risk reduction is still going to be pretty small for those individuals and that's only magnified in primary prevention. So the short answer is I have no reason to believe that lower is better is not applicable in primary prevention, but I do know that the cost and what entails to get there, you don't get as much return on investment. I do want to say one last thing though. We're talking about lower is better, and I know these investigators know this well, but it's not only just how low but how long and I think that's where primary prevention about to go to clinic and I play the long game for primary prevention that we know we've magnified these benefits over the long term and even a little bit early in life can pay off long dividends. So that's how I look at it. Dr Greg Hundley: Very nice. Well, listeners we want to thank Dr. Prakriti Gaba, Dr. Marc Sabatine, both from Brigham and Women's Hospital and also our own associate editor, Dr. Amit Khera from University of Texas Southwestern Medical Center for bringing us this study involving patients with arteriosclerotic cardiovascular disease indicating that long-term achievement of lower LDL cholesterol levels down to values less than 20 mg/dL was associated with a lower risk of cardiovascular outcomes and not and not an increase in the risk of significant safety related events. Well, on behalf of Peder, Carolyn and myself, we want to wish you a great week and we will catch you next week on the run. Dr. Greg Hundley: This program is copyright of the American Heart Association 2023. The opinions expressed by speakers in this podcast are their own and not necessarily those of the editors or of the American Heart Association. For more, please visit ahajournals.org.

The science of storytelling is a highly relevant topic in today's workplace. It explores how stories can be used to inspire change and create engagement among employees. By crafting narratives that resonate with people's emotions and values, storytellers can capture their audience's attention and make complex ideas more accessible and memorable. In today's fast-paced and ever-changing workplace, the ability to communicate effectively and inspire change is more important than ever. By mastering the science of storytelling, individuals and organizations can tap into the power of narrative to connect with their audiences, build trust, and drive meaningful change. So, if you're looking to inspire change at work, consider harnessing the power of storytelling to get your message across. Whether you're a manager looking to motivate your team, an entrepreneur looking to inspire investors, or simply someone who wants to communicate more effectively, this podcast will provide you with practical tips and strategies to use the power of storytelling to inspire change at work. About Richard Newman At the age of 18, Richard began his quest to uncover the fundamental principles of communication. He lived in the Himalayan foothills with Tibetan monks, with whom he had to communicate non-verbally due to their language barrier. Richard's research on non-verbal communication was published in the prestigious Journal of Psychology. His study proved that minor behavior modifications could lead to a 44% increase in leadership ratings and a 59% rise in electoral votes. Richard is the founder of Body Talk, the top evidence-based training program on communication psychology. He is the author of the book "You Were Born to Speak" and his forthcoming book, "Lift Your Impact: Transform Your Mindset, Influence, and Future to Elevate Your Work, Team, and Life," offers innovative communication strategies that can help professionals increase their impact and influence. This groundbreaking book will be released on May 2nd 2023. Connecting with Richard Newman Instagram https://www.instagram.com/richardnewmanspeaks/ LinkedIn https://www.linkedin.com/in/richardnewmanspeaks/ Website https://ukbodytalk.com/ His upcoming book Lift Your Impact: Transform Your Mindset, Influence, and Future to Elevate Your Work, Team, and Life https://www.amazon.com/Lift-Your-Impact-Transform-Influence/dp/1265086141  What We Discussed in this Episode: Why is it difficult for managers to inspire and empathize with their teams at work? How can changing your communication style help inspire and onboard more people? The science of storytelling: what happens in the brain when we tell stories effectively? If Richard were the CEO of a Fortune 500 company, what would be his first steps to unleash the power of communication and inspire his teams? How can introverts overcome their reservations about participating in group activities? Richard Newman's expert advice for overcoming one of the biggest workplace challenges: feeling a sense of belonging.   Bonus -Four Reasons for Low Employee Engagement Rates and How to Improve It https://www.peoplekult.com/post/four-reasons-for-low-employee-engagement-rates-and-how-to-improve-it    ### This episode is hosted by Ivan Palomino - He is a Learning Strategist and Behavioral Designer. Ivan helps organizations build human-centric work cultures. This episode is brought to you by PeopleKult - the next generation work culture powered by brain and data science. ###

Let me know your thoughts about this episode at www.Facebook.com/TerminalValueDoug and Erin discussed the importance of failure to achieve long-term success and how it is a critical part of maintaining an abundance mindset to bring your Erin is host of the Improve It podcastwww.learntoimproveit.comTo find all of the platforms where this podcast is published and our YouTube channels, please visit www.TerminalValuePodcast.com and leave a review.

When you find your voice, you don't find something new inside of you; instead, you find a little more of yourself. That's what our guest for today helps her clients “get comfortable with the uncomfortable.” CEO and Founder of Improve It! Erin Diehl shares how she helped countless individuals find their voice through the art of improvisation.   Erin Diehl is a graduate of Clemson University and former experiential marketing and recruiting professional as well as a veteran improviser from the top improvisational training programs in Chicago, including The Second City, i.O. Theater and The Annoyance Theatre. Erin conducts workshops across the country leveraging improvisational techniques to improve employees' skills in corporate settings.   Her work with clients such as United Airlines, PepsiCo, Groupon, Deloitte, Motorola, Lowe's, Accenture, Walgreens, and The Obama Foundation earned her the 2014 Chicago RedEye Big Idea Award and has nominated her for the 2015-2019 Chicago Innovations Award. Erin was a speaker for Disrupt HR Chicago, hosted the 2016 RedEye Big Idea Awards, and has been a speaker for HRMAC Chicago, SHRM Chicago, Disrupt HR, the Business Marketing Association, and Emerging Leaders of the Chicagoland Chamber of Commerce. She is also a proud member of The Chicago Innovation Awards Women's Cohort and a graduate of the Goldman Sachs 10,000 Small Business Program.    Among her many accolades, Erin is most proud of successfully coercing over 12,000 professionals to chicken dance.   Connect with her at: Website: https://www.learntoimproveit.com/ LinkedIn: https://www.linkedin.com/in/erindiehl/ IG: https://www.instagram.com/keepinitrealdiehl   Listen to her podcast: The improve it! Podcast at: https://www.learntoimproveit.com/podcast Access her Hybrid Hype worksheet: https://www.learntoimproveit.com/hybrid-hype   Show notes: [0:00] Intro [0:10] Her experiences with the people who take her course [3:43] On having her own podcast: The improve it! Podcast [6:14] Her rewards for having her podcast [7:40] What does money mean to Erin? [9:17] Where to find more of Erin? [11:00] Outro Connect with Bill Bloom  Web: https://www.bloomfinancialco.com/ https://bloomfinancialco.kartra.com/page/bNJ87 Email: bill@bloomfinancial.us  LinkedIn: https://www.linkedin.com/in/bloomfinancial/ FB: https://www.facebook.com/retireasyoudesirepodcast   Securities and investment advisory services are offered through Woodbury Financial Services, Inc. (WFS), member FINRA/SIPC. WFS. is separately owned, and other entities and/or marketing names, products, or services referenced here are independent of WFS.   Views expressed in this podcast are for general informational purposes only and are not intended to provide or be a substitute for specific professional financial, tax or legal advice or recommendations for any individuals. Information is based on sources believed to be reliable; however, their accuracy or completeness cannot be guaranteed.

When you find your voice, you don't find something new inside of you; instead, you find a little more of yourself. That's what our guest for today helps her clients “get comfortable with the uncomfortable.” CEO and Founder of Improve It! Erin Diehl shares how she helped countless individuals find their voice through the art of improvisation.   Erin Diehl is a graduate of Clemson University and former experiential marketing and recruiting professional as well as a veteran improviser from the top improvisational training programs in Chicago, including The Second City, i.O. Theater and The Annoyance Theatre. Erin conducts workshops across the country leveraging improvisational techniques to improve employees' skills in corporate settings.   Her work with clients such as United Airlines, PepsiCo, Groupon, Deloitte, Motorola, Lowe's, Accenture, Walgreens, and The Obama Foundation earned her the 2014 Chicago RedEye Big Idea Award and has nominated her for the 2015-2019 Chicago Innovations Award. Erin was a speaker for Disrupt HR Chicago, hosted the 2016 RedEye Big Idea Awards, and has been a speaker for HRMAC Chicago, SHRM Chicago, Disrupt HR, the Business Marketing Association, and Emerging Leaders of the Chicagoland Chamber of Commerce. She is also a proud member of The Chicago Innovation Awards Women's Cohort and a graduate of the Goldman Sachs 10,000 Small Business Program.    Among her many accolades, Erin is most proud of successfully coercing over 12,000 professionals to chicken dance.   Connect with her at: Website: https://www.learntoimproveit.com/ LinkedIn: https://www.linkedin.com/in/erindiehl/ IG: https://www.instagram.com/keepinitrealdiehl   Listen to her podcast: The improve it! Podcast at: https://www.learntoimproveit.com/podcast Access her Hybrid Hype worksheet: https://www.learntoimproveit.com/hybrid-hype   Show notes: [0:41] How Erin started in the world of comedy [3:51] Transitioning to making scripts from scratch [5:23] Being able to find her voice through improvisation [8:15] On people not finding their BIG [10:00] Outro   Connect with Bill Bloom  Web: https://www.bloomfinancialco.com/ https://bloomfinancialco.kartra.com/page/bNJ87 Email: bill@bloomfinancial.us  LinkedIn: https://www.linkedin.com/in/bloomfinancial/ FB: https://www.facebook.com/retireasyoudesirepodcast   Securities and investment advisory services are offered through Woodbury Financial Services, Inc. (WFS), member FINRA/SIPC. WFS. is separately owned, and other entities and/or marketing names, products, or services referenced here are independent of WFS.   Views expressed in this podcast are for general informational purposes only and are not intended to provide or be a substitute for specific professional financial, tax or legal advice or recommendations for any individuals. Information is based on sources believed to be reliable; however, their accuracy or completeness cannot be guaranteed.

In this podcast, Robert P. Guigliano, MD, SM, discusses the findings from a secondary analysis from the IMPROVE-IT study on the association of serial high-sensitivity cardiac troponin T with subsequent cardiovascular events in patients stabilized after acute coronary syndrome, including if it is worthwhile to measure troponin and how often.

Today on the PR Talk Podcast, Amy Rosenberg explores a different way of creating a positive company culture with Erin Diehl, founder and CEO of Improve it!, a unique professional development company, and host of the Improve It! Podcast. Erin shares how she uses the connection between improv and business development to help others grow professionally. Read the full write-up at https://www.veracityagency.com/podcast/erin-diehl/ Learn more about your ad choices. Visit megaphone.fm/adchoices

Introducing Erin Diehl Erin “Big” Diehl is a Business Improv Edutainer, Failfluencer, and Professional Zoombie. Through a series of unrelated dares, Erin created Improve It!, a unique professional development company that pushes others to laugh, learn, play, and grow. She is the proud host of The Improve It! Podcast, which helps develop leaders and teams through play, improv, and experiential learning. Among her many accolades, Erin is most proud of successfully coercing over 28,000 professionals to chicken dance.  What problem do you solve? She will help you develop yourself or your team as a leader through play, laughter, improv, and experiential learning. Show Notes: Improv takes people's shields off and opens them up. It suspends judgment and helps people listen to each other. It helps teams feel seen, heard, and valued. It helps us tap into our inner child and let them become more creative. While you can't fix your culture in a single improv session, you can work on a single issue and it's also the beginning of learning about others in the workplace. It helps teams connect. If leaders are vulnerable in a session, it will help teams connect with them more. Erin says Failure + Frequency = The Fundamental of Success You create things you never would have created when you fail. Just be persistent. You don't learn from winning. People that never fail, never try. It is possible to connect over Zoom. Erin has had improv workshops over Zoom.  Use the breakout rooms. Make sure there is an agenda. “No agenda, no attenda.” People may be more likely to get involved in the chat function than they are in person. If you want someone engaged, call on them. Things leaders should change or implement in their organization Feedback: Not giving it but leaders receiving it. “What is one thing I can start doing and what is one thing I should stop doing as a leader?”  Ask this same about your team “What is one thing we can start doing and what is one thing we should stop doing as a team?”  Celebrating wins. Create a Slack Channel or Teams Celebrate your failures. Fail Yeah! Erin Diehl's Recharge Round What habit do you think has led to success in your life? Exercise and meditation. If you had one do-over, what would it be? When her grandfather passed away, she removed herself because she didn't want to be there the last few days and see him not well. She regretted that choice and then she made sure to be there for her grandmother.  Erin Diehl's website: learntoimproveit.com Erin's offer — Free download Hybrid-Hype Erin's Podcast: learntoimproveit.com/podcast Connect with Erin Diehl: Instagram LinkedIn Learn more about Gary's Mastermind group at goascend.biz/mastermind/ Get your Daily Dose of Positive at SimplePositiveActions.com

On today's episode of the As Told By Nomads podcast, Tayo chats with Erin Diehl, the founder and CEO of a professional development company, a recovering perfectionist, and a podcast host on her own show, Improve It! Together, they kick off the episode by talking about Erin's love for entertainment, how it blossomed at a young age, and how it wasn't until COVID that she found her true calling: making people laugh online and over Zoom. She recalls sleepless nights working on improv sets with her team, and goes on to remember bygone days when she suffered from being a perfectionist. Since starting meditation and learning to let go, her love for her business has only grown. As a self proclaimed recovering perfectionist, Diehl has finally come to understand how and why failure is so vital to our personal progress. She notes how helpful improv was to this journey, and that since failure is inevitable, it's best to embrace it much as she has done with her genius brainchild, Laugh Break. Corporate clients hire her and her team of improv studs to host a 30-60 minute Laugh Break during a meeting over Zoom, where her goal is to make our virtual realities a little bit more enjoyable. Both Tayo and Erin close out the episode with a final note on knowing your worth - after all, life gets really good when we start to appreciate how wonderful we are. The Finer Details of This Episode:Erin's love for entertainment at a young age COVID's effect on her live performances Sleepless nights working on improv Life as a recovering perfectionistMeditation and learning to let go Why failure is vital for growth Improv practices Contributing to positive energy Feeling comfortable working from home Laugh breaks Knowing your worthLinks: Connect with Erin Diehl on: Improve It! podcast Improve It! Homepage Erin Diehl on Instagram: https://www.instagram.com/diehloftheday/ Improve It! on Instagram: https://www.instagram.com/learntoimproveit/ Connect with Tayo Rockson and the As Told By Nomads Podcast:Tayo's WebsiteTayo on LinkedIn Tayo on TwitterTayo on YouTubeTayo on TikTokAs Told by Nomads PodcastUYD ManagementUYD Collective See acast.com/privacy for privacy and opt-out information.

Learn Speak Teach Episode #21. Leadership skills are like muscles- they must be developed and exercised continuously. To stay in shape, you need to push yourself past your comfort zone and take on new challenges. They include things like communication, empathy, listening, decision-making, and managing change. Some people think leadership is about being in charge and others think it's about being a good listener. But there are many different ways of leading your team towards success and achieving your goals, so make sure you know what works for you and your team by tuning to this episode with Erin Diehl! Erin is a Business Improv Edutainer, Failfluencer, and Professional Zoombie who is ready to help you “IMPROVE IT.” Her mission in life is to help you develop teams and leaders through play, improv, and experiential learning. Erin has helped everyone from Fortune 500 companies to small mom and pop shops transform their business, leadership, and people through play! Tune in! During this episode, you will learn about; [03:06] Introduction to the show. Why you should add Truffle Salt to your cart Now!! [06:50] Meet today's guest, Erin Diehl [07:50] How Erin became a ‘Failfluencer.' [10:55] How Erin saw the Covid pandemic as an opportunity rather than a setback [13:37] The post-covid goodies that Erin could not get without the pandemic [15:58] How you can take Erin's workshops [17:40] One of the ten power skills Erin teaches at the workshop [23:02] Why she refers to herself as a Professional ‘ZOOMbie.' [23:43] Why you should embrace the suck after disappointments [31:12] How her infertility struggles led her to meditation and mindfulness [33:32] Erin's mindfulness meditation routine you can copy [36:12] Rapid Fire Round [45:54] Where you can get Erin's podcast [46:50] Chicken dance Notable Quotes ~ “Your successes and your failures are both equal breaks in the foundation that you are building. You won't always succeed at everything, but you won't always fail, either. Each setback or victory is an important building block for your future success.” ~ “Having an occasional setback can be a real blessing in disguise. When you need to cancel plans or embrace your emotions, don't forget that it takes time to grow stronger and smarter. Embrace the suck, it takes time to overcome your disappointments.” ~ “Before you can help others, you need to know how to help yourself first. You have to fill the kettle up before you start sharing, but you cannot fill the kettle if there's nothing to fill it.” Keep In Touch with Erin Diehl: Website: https://www.learntoimproveit.com/ LinkedIn: https://www.linkedin.com/in/erindiehl/ Instagram: https://www.instagram.com/keepinitrealdiehl/ Podcast: https://www.learntoimproveit.com/podcast Website: https://www.realbusinessconnections.com/ — Follow Balbert… Facebook www.facebook.com/balbertmarketing Instagram: www.instagram.com/realbenalbert/ LinkedIn: www.linkedin.com/in/ben-albert-a74737106/ – LST is made possible by www://balbertmarketing.com/

If making small talk makes someone anxious, it may just be because they have a fear of such interactions, and my guest today, Rich Gallagher, can help them overcome it through his practice as a therapist. Or, someone's anxiety around small talk can be based in part on simply not knowing how to do it, and in that case, Rich helps them by teaching them the mechanics of conversation, which he shares in his book Stress-Free Small Talk, as well as on today's show.Rich and I begin our conversation with how small talk is important as an on-ramp to bigger things, how it's a skill that can be developed like any other, and how learning its mechanics can dampen the anxiety you feel about taking part in it. We then turn to these mechanics of making comfortable and effective small talk, including doing prep work, embracing tried-and-true openers, and avoiding talking too much yourself. We also discuss how to join conversations that are already underway, manage committing a faux pas, acknowledge others to build connection, and end a conversation gracefully. We end our conversation with small talk strategies for first dates and job interviews, and what to do when you go to a party where you only know the host.Resources Related to the PodcastRelated AoM articles on small talk/social skills:How to Make Small TalkSeries on overcoming shynessYour 4 Social GiftsHow to Enter a Room Like a BossWhat to Do at an Event Where You Don't Know AnyoneHow to Think of Questions to Ask PeopleHow to Use Body Language to Create a Dynamite First ImpressionHow to End a ConversationHow to Make a Great Last ImpressionHow to Recover from a Bad First ImpressionHow to Ask Better Questions on a First DateHow to Give a ComplimentSunday Firesides: Want to Solve Your Social Problems? Get Over Your SelfRelated AoM podcasts on small talk:#317: Why Your First Impression Matters & How to Improve It#406: Why You Need to Embrace Small TalkThe Rotary's 4-Way Test

Digital connections permeate our lives-and so do data breaches. Given that we must be online for basic communication, finance, healthcare, and more, it is alarming how difficult it is to create rules for securing our personal information. Despite the passage of many data security laws, data breaches are increasing at a record pace. In Breached!: Why Data Security Law Fails and How to Improve It (Oxford UP, 2022), Daniel Solove and Woodrow Hartzog, two of the world's leading experts on privacy and data security, argue that the law fails because, ironically, it focuses too much on the breach itself. Drawing insights from many fascinating stories about data breaches, Solove and Hartzog show how major breaches could have been prevented or mitigated through a different approach to data security rules. Current law is counterproductive. It pummels organizations that have suffered a breach but doesn't address the many other actors that contribute to the problem: software companies that create vulnerable software, device companies that make insecure devices, government policymakers who write regulations that increase security risks, organizations that train people to engage in risky behaviors, and more. Although humans are the weakest link for data security, policies and technologies are often designed with a poor understanding of human behavior. Breached! corrects this course by focusing on the human side of security. Drawing from public health theory and a nuanced understanding of risk, Solove and Hartzog set out a holistic vision for data security law-one that holds all actors accountable, understands security broadly and in relationship to privacy, looks to prevention and mitigation rather than reaction, and works by accepting human limitations rather than being in denial of them. The book closes with a roadmap for how we can reboot law and policy surrounding data security. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network

Digital connections permeate our lives-and so do data breaches. Given that we must be online for basic communication, finance, healthcare, and more, it is alarming how difficult it is to create rules for securing our personal information. Despite the passage of many data security laws, data breaches are increasing at a record pace. In Breached!: Why Data Security Law Fails and How to Improve It (Oxford UP, 2022), Daniel Solove and Woodrow Hartzog, two of the world's leading experts on privacy and data security, argue that the law fails because, ironically, it focuses too much on the breach itself. Drawing insights from many fascinating stories about data breaches, Solove and Hartzog show how major breaches could have been prevented or mitigated through a different approach to data security rules. Current law is counterproductive. It pummels organizations that have suffered a breach but doesn't address the many other actors that contribute to the problem: software companies that create vulnerable software, device companies that make insecure devices, government policymakers who write regulations that increase security risks, organizations that train people to engage in risky behaviors, and more. Although humans are the weakest link for data security, policies and technologies are often designed with a poor understanding of human behavior. Breached! corrects this course by focusing on the human side of security. Drawing from public health theory and a nuanced understanding of risk, Solove and Hartzog set out a holistic vision for data security law-one that holds all actors accountable, understands security broadly and in relationship to privacy, looks to prevention and mitigation rather than reaction, and works by accepting human limitations rather than being in denial of them. The book closes with a roadmap for how we can reboot law and policy surrounding data security. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/national-security

Digital connections permeate our lives-and so do data breaches. Given that we must be online for basic communication, finance, healthcare, and more, it is alarming how difficult it is to create rules for securing our personal information. Despite the passage of many data security laws, data breaches are increasing at a record pace. In Breached!: Why Data Security Law Fails and How to Improve It (Oxford UP, 2022), Daniel Solove and Woodrow Hartzog, two of the world's leading experts on privacy and data security, argue that the law fails because, ironically, it focuses too much on the breach itself. Drawing insights from many fascinating stories about data breaches, Solove and Hartzog show how major breaches could have been prevented or mitigated through a different approach to data security rules. Current law is counterproductive. It pummels organizations that have suffered a breach but doesn't address the many other actors that contribute to the problem: software companies that create vulnerable software, device companies that make insecure devices, government policymakers who write regulations that increase security risks, organizations that train people to engage in risky behaviors, and more. Although humans are the weakest link for data security, policies and technologies are often designed with a poor understanding of human behavior. Breached! corrects this course by focusing on the human side of security. Drawing from public health theory and a nuanced understanding of risk, Solove and Hartzog set out a holistic vision for data security law-one that holds all actors accountable, understands security broadly and in relationship to privacy, looks to prevention and mitigation rather than reaction, and works by accepting human limitations rather than being in denial of them. The book closes with a roadmap for how we can reboot law and policy surrounding data security. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/communications

Digital connections permeate our lives-and so do data breaches. Given that we must be online for basic communication, finance, healthcare, and more, it is alarming how difficult it is to create rules for securing our personal information. Despite the passage of many data security laws, data breaches are increasing at a record pace. In Breached!: Why Data Security Law Fails and How to Improve It (Oxford UP, 2022), Daniel Solove and Woodrow Hartzog, two of the world's leading experts on privacy and data security, argue that the law fails because, ironically, it focuses too much on the breach itself. Drawing insights from many fascinating stories about data breaches, Solove and Hartzog show how major breaches could have been prevented or mitigated through a different approach to data security rules. Current law is counterproductive. It pummels organizations that have suffered a breach but doesn't address the many other actors that contribute to the problem: software companies that create vulnerable software, device companies that make insecure devices, government policymakers who write regulations that increase security risks, organizations that train people to engage in risky behaviors, and more. Although humans are the weakest link for data security, policies and technologies are often designed with a poor understanding of human behavior. Breached! corrects this course by focusing on the human side of security. Drawing from public health theory and a nuanced understanding of risk, Solove and Hartzog set out a holistic vision for data security law-one that holds all actors accountable, understands security broadly and in relationship to privacy, looks to prevention and mitigation rather than reaction, and works by accepting human limitations rather than being in denial of them. The book closes with a roadmap for how we can reboot law and policy surrounding data security. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science-technology-and-society

Digital connections permeate our lives-and so do data breaches. Given that we must be online for basic communication, finance, healthcare, and more, it is alarming how difficult it is to create rules for securing our personal information. Despite the passage of many data security laws, data breaches are increasing at a record pace. In Breached!: Why Data Security Law Fails and How to Improve It (Oxford UP, 2022), Daniel Solove and Woodrow Hartzog, two of the world's leading experts on privacy and data security, argue that the law fails because, ironically, it focuses too much on the breach itself. Drawing insights from many fascinating stories about data breaches, Solove and Hartzog show how major breaches could have been prevented or mitigated through a different approach to data security rules. Current law is counterproductive. It pummels organizations that have suffered a breach but doesn't address the many other actors that contribute to the problem: software companies that create vulnerable software, device companies that make insecure devices, government policymakers who write regulations that increase security risks, organizations that train people to engage in risky behaviors, and more. Although humans are the weakest link for data security, policies and technologies are often designed with a poor understanding of human behavior. Breached! corrects this course by focusing on the human side of security. Drawing from public health theory and a nuanced understanding of risk, Solove and Hartzog set out a holistic vision for data security law-one that holds all actors accountable, understands security broadly and in relationship to privacy, looks to prevention and mitigation rather than reaction, and works by accepting human limitations rather than being in denial of them. The book closes with a roadmap for how we can reboot law and policy surrounding data security. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/law

Digital connections permeate our lives-and so do data breaches. Given that we must be online for basic communication, finance, healthcare, and more, it is alarming how difficult it is to create rules for securing our personal information. Despite the passage of many data security laws, data breaches are increasing at a record pace. In Breached!: Why Data Security Law Fails and How to Improve It (Oxford UP, 2022), Daniel Solove and Woodrow Hartzog, two of the world's leading experts on privacy and data security, argue that the law fails because, ironically, it focuses too much on the breach itself. Drawing insights from many fascinating stories about data breaches, Solove and Hartzog show how major breaches could have been prevented or mitigated through a different approach to data security rules. Current law is counterproductive. It pummels organizations that have suffered a breach but doesn't address the many other actors that contribute to the problem: software companies that create vulnerable software, device companies that make insecure devices, government policymakers who write regulations that increase security risks, organizations that train people to engage in risky behaviors, and more. Although humans are the weakest link for data security, policies and technologies are often designed with a poor understanding of human behavior. Breached! corrects this course by focusing on the human side of security. Drawing from public health theory and a nuanced understanding of risk, Solove and Hartzog set out a holistic vision for data security law-one that holds all actors accountable, understands security broadly and in relationship to privacy, looks to prevention and mitigation rather than reaction, and works by accepting human limitations rather than being in denial of them. The book closes with a roadmap for how we can reboot law and policy surrounding data security. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/technology

Digital connections permeate our lives-and so do data breaches. Given that we must be online for basic communication, finance, healthcare, and more, it is alarming how difficult it is to create rules for securing our personal information. Despite the passage of many data security laws, data breaches are increasing at a record pace. In Breached!: Why Data Security Law Fails and How to Improve It (Oxford UP, 2022), Daniel Solove and Woodrow Hartzog, two of the world's leading experts on privacy and data security, argue that the law fails because, ironically, it focuses too much on the breach itself. Drawing insights from many fascinating stories about data breaches, Solove and Hartzog show how major breaches could have been prevented or mitigated through a different approach to data security rules. Current law is counterproductive. It pummels organizations that have suffered a breach but doesn't address the many other actors that contribute to the problem: software companies that create vulnerable software, device companies that make insecure devices, government policymakers who write regulations that increase security risks, organizations that train people to engage in risky behaviors, and more. Although humans are the weakest link for data security, policies and technologies are often designed with a poor understanding of human behavior. Breached! corrects this course by focusing on the human side of security. Drawing from public health theory and a nuanced understanding of risk, Solove and Hartzog set out a holistic vision for data security law-one that holds all actors accountable, understands security broadly and in relationship to privacy, looks to prevention and mitigation rather than reaction, and works by accepting human limitations rather than being in denial of them. The book closes with a roadmap for how we can reboot law and policy surrounding data security.

When I was in college I absolutely hated writing papers.   The paper that I spent the most amount of time trying to write was my resume. It ended up being one page.   Anyone looking to hire me would have this one page to learn all about me and make a decision of whether or not to hire me.   Financial lenders have one document to look at to determine whether or not they want to lend you money. It is your credit report, which gives them the details of your credit score.   Today I am going to give you some tips on how to build up your credit score.   6:52 What affects your credit score? 11:04 Open a secured credit card account. 13:31 Credit builder loans 14:44 Credit building Apps 15:46 Review your credit report 17:23 Dispute any charges that are not yours   Check out my YouTube channel here. Follow me on Twitter and Instagram.    Resources: How to Raise Your Credit Score 100 Points or More in Less Than 5 Months How to Dispute Your Credit Report and Get Negative Items Removed What is a Bad Credit Score? (Plus How to Improve It) 7 Best Credit Repair Companies of 2022 https://wealthhackerlabs.com/ask/  

For the past two decades, there has been an epidemic of data breaches, from Target, to Home Depot, to Equifax, to Uber, just to name a few. In their new book, “Breached! Why Data Security Law Fails and How to Improve It,” Daniel Solove, the John Marshall Harlan Research Professor of Law at the George Washington University Law School, and Woodrow Hartzog, Professor of Law and Computer Science at Northeastern University, tell us why current data security law fails and how we can improve it. Stephanie Pell spoke with Dan and Woody about a number of issues they raise in their book, including how current data security law overemphasizes the conduct of breached entities and fails to distribute responsibility among a range of actors in the data ecosystem that contributes to the data breach. They also talked about their ideas for more proactive data security laws that work to reduce the harm caused by data breaches once they occur, encourage greater integration of privacy and security principles, and promote data security rules and practices designed with humans in mind. Support this show http://supporter.acast.com/lawfare. See acast.com/privacy for privacy and opt-out information.

When you find your voice, you don't find some new thing inside of you; instead, you find a little more of yourself. That's what our guest for today helps her clients “get comfortable with the uncomfortable.” CEO and Founder of Improve It! Erin Diehl shares how she helped countless individuals find their voice through the art of improvisation.   Erin Diehl is a graduate of Clemson University and former experiential marketing and recruiting professional as well as a veteran improviser from the top improvisational training programs in Chicago, including The Second City, i.O. Theater and The Annoyance Theatre. Erin conducts workshops across the country leveraging improvisational techniques to improve employees' skills in corporate settings.   Her work with clients such as United Airlines, PepsiCo, Groupon, Deloitte, Motorola, Lowe's, Accenture, Walgreens, and The Obama Foundation earned her the 2014 Chicago RedEye Big Idea Award and has nominated her for the 2015-2019 Chicago Innovations Award. Erin was a speaker for Disrupt HR Chicago, hosted the 2016 RedEye Big Idea Awards, and has been a speaker for HRMAC Chicago, SHRM Chicago, Disrupt HR, the Business Marketing Association, and Emerging Leaders of the Chicagoland Chamber of Commerce. She is also a proud member of The Chicago Innovation Awards Women's Cohort and a graduate of the Goldman Sachs 10,000 Small Business Program.    Among her many accolades, Erin is most proud of successfully coercing over 12,000 professionals to chicken dance.   Connect with her at: Website: https://www.learntoimproveit.com/ LinkedIn: https://www.linkedin.com/in/erindiehl/ IG: https://www.instagram.com/keepinitrealdiehl/   Listen to her podcast: The improve it! Podcast at: https://www.learntoimproveit.com/podcast   Access her Hybrid Hype worksheet: https://www.learntoimproveit.com/hybrid-hype   Show notes: [1:53] How Erin started in the world of comedy [5:03] Transitioning to making scripts from scratch [6:35] Being able to find her voice through improvisation [9:27] On people not finding their BIG [11:14] Her experiences with the people who take her course [14:59] On having her own podcast: The improve it! Podcast [17:29] Her rewards for having her podcast [18:55] What does money mean to Erin? [20:32] Where to find more of Erin?   Connect with Bill Bloom  Web: https://www.bloomfinancialco.com/ https://bloomfinancialco.kartra.com/page/bNJ87 Email: bill@bloomfinancial.us  LinkedIn: https://www.linkedin.com/in/bloomfinancial/ FB: https://www.facebook.com/retireasyoudesirepodcast     Securities and investment advisory services offered through Woodbury Financial Services, Inc. (WFS) member FINRA/SIPC. WFS. is separately owned and other entities and/or marketing names, products or services referenced here are independent of WFS.     Views expressed in this podcast are for general informational purposes only and are not intended to provide or be a substitute for specific professional financial, tax or legal advice or recommendations for any individuals. Information is based on sources believed to be reliable; however, their accuracy or completeness cannot be guaranteed.

WOW - this episode with Erin Diehl, host of the Improve It! Podcast and founder of Improve It! is amazing! Erin and Traci chit chat about all of the fun that Jan Jannerson of @NotSHRMApproved brings to their lives, the beauty of Improv and fun it brings to team building, and the future of VR and remote trainings! This is not an episode to miss! Be sure to share this one with your friends! (P.S. If you're on Spotify, you can watch the video episode!) Connect with Erin here: https://instabio.cc/linkstoimproveit Connect with Traci here: https://linktr.ee/HRTraci This episode is brought to you by Namely - check it out: https://www.namely.com Sign-up for Human Times Newsletter: https://industryslice.com/subscribers/dbc8cfad-6689-4447-aeb1-9bd98d0a2b61?rh_ref=f00c86a3 Traci has been selected to be a speaker and panelist at the Hacking HR 2022 Global Online Conference! Register to join for FREE from March 7-11, 2022: https://www.hackinghrlab.io/46 Disclaimer: Thoughts, opinions, and statements made on this podcast are not a reflection of the thoughts, opinions, and statements of the Company Traci Rubin is actively employed by. --- Send in a voice message: https://anchor.fm/hrtraci/message Support this podcast: https://anchor.fm/hrtraci/support

In this episode of Own Your Career, Andy is joined by Erin Diehl, business improv educator, failfluencer, and professional zoombie who is ready to help you Improve It! In this episode, Erin shares what improv is, why we should be thinking about it in business and meetings, and how it can help you own your career. She also gives insight into how run a great virtual meeting with virtual icebreakers. Connect with Andy Storch here: https://andystorch.com/ (andystorch.com) https://www.linkedin.com/in/andystorch/ (linkedin.com/in/andystorch) https://tdtt.us/ (tdtt.us/) http://ownyourcareerownyourlife.com/bonus/ (ownyourcareerownyourlife.com/bonus) Connect with Erin Diehl: https://www.linkedin.com/in/erindiehl/ (https://www.linkedin.com/in/erindiehl/) https://www.learntoimproveit.com/ (https://www.learntoimproveit.com/) @keepinitrealdiehl

In this episode of Own Your Career, Andy is joined by Erin Diehl, business improv educator, failfluencer, and professional zoombie who is ready to help you Improve It! In this episode, Erin shares what improv is, why we should be thinking about it in business and meetings, and how it can help you own your career. She also gives insight into how run a great virtual meeting with virtual icebreakers. Connect with Andy Storch here: https://andystorch.com/ (andystorch.com) https://www.linkedin.com/in/andystorch/ (linkedin.com/in/andystorch) https://tdtt.us/ (tdtt.us/) http://ownyourcareerownyourlife.com/bonus/ (ownyourcareerownyourlife.com/bonus) Connect with Erin Diehl: https://www.linkedin.com/in/erindiehl/ (https://www.linkedin.com/in/erindiehl/) https://www.learntoimproveit.com/ (https://www.learntoimproveit.com/) @keepinitrealdiehl

Today's guest is Erin Diehl, founder and CEO of professional development company, Improve It! Learn how Erin embraces a mindset of “failfluence” and uses improvisational comedy tactics to create cultures of trust, teamwork, and collaboration across some of the largest organizations in the business world.

If You Can't Measure It, You Can't Improve It! http://www.LaunchYourFarm.com/Episode54 Welcome back to our 54th episode of the Launch Your Farm Show where I interview Brandon Doyle with Re/Max Results in Minnesota. Today Brandon shares how his father convinced him to get into the business and join his team. As a published author, speaker and regular content contributor to many major online real estate publications. One of Brandon's passions is metrics and how important it is to track your business and how you can increase your business when you learn to focus on the right things. In this episode Brandon and I talk about: · Why you need to take the time to track your business and what simple metrics you should be considering. · Brandon shares how he uses his passions to connect with other like-minded people in his community and how you can do the same. · What metrics Brandon uses when choosing a farm and how you can track your own numbers in your farm. · A SUPER easy way to track your business to ensure you get more deals from all your strategies. · How to create your own customized content marketing plan to add value to your farm. · Plus a ton of other ideas that you can use to grow geographic farm! Connect with Brandon on Facebook and his smart home tech info @hometechdecisions You can find his books on Amazon at https://www.amazon.com/Brandon-Doyle/e/B01F7Z7PKU/ref=dp_byline_cont_pop_book_1 YOUR BEST BOOK – Check out Brandon's favorite book at the moment. “Ninja Selling” by Larry Kendall To get a copy you can order it here: Canada – https://www.amazon.ca/dp/1626342849 USA - https://www.amazon.com/dp/1626342849 “What To Post” by Chelsea Peitz To get a copy you can order it here: Canada – https://www.amazon.ca/dp/1670832244 USA - https://www.amazon.com/dp/1670832244 Be sure to like and subscribe as well as check our website and other social channels. Your Friend In Farming, Ryan Smith Launch Your Farm Website - http://www.LaunchYourFarm.com Facebook - http://www.Facebook.com/LaunchYourFarm

Michelle Ledet Henley is President of TMG Frontline Solutions where she has spent the past 25 years helping hundreds of organizations navigate the difficult waters of organizational change using a game-based simulation. Her enthusiastic facilitation style along with the innovative workshop design bring the workforce (even the most skeptical among them) energetically onboard with their site's reliability improvement efforts. Co-authoring various articles and the book Level 5 - Leadership at Work, the sequel to the popular Don't Just Fix It, Improve It, Michelle has become a thought leader on the emerging and often misunderstood topic of defect elimination. --- Support this podcast: https://anchor.fm/practical-reliability/support

Renelle Briggs is a confidence mentor, digital creator, and founder of the Confidence Club and the host of the Confidence Club Podcast. She teaches people to show up confidently in their life and create financial freedom. On this week's episode Renelle and I talk about being true to yourself, how to change the stories we tell yourself about money and why mindset is so important when building up your confidence. Connect with Renelle Briggs: Instagram: @renellebriggs Confidence Club Podcast with Renelle Briggs Clubhouse: @renellebriggs and The Confidence Crew room Resources: What is Self-Confidence + 9 Ways to Improve It by Courtney E. Ackerman, M.A. Why Self-Confidence is More Important Than You Think by Barbara Parkway Ph.D How Generation Z is Altering the Face of Entrepreneurship for Good by Chidike Samuelson Gen Z Entrepreneurs are Thriving During the Pandemic by Ian Fox Think and Grow Rich by Napoleon Hill Your Are a Badass by Jen Sincero You Are a Badass at Making Money by Jen Sincero The Four Agreements by Miguel Ruiz Humans ‘R' Us Episode 7: Garrett Philbin - Financial Coach and Founder of Be Awesome Not Broke Make sure you hit SUBSCRIBE so you don't miss out on any upcoming episodes. And, if you enjoyed this episode, please tell a friend about it. Let's grow the Humans ‘R' Us Community!

Founders TIME #5 "Quality in Business" Conversation with Diane Elko, MBA Business Advice for Vetpreneurs, Veterans, Military & Military Spouses that are starting their own entrepreneurial journey. Here you will find: YOU would need to START, SCALE, SUCCEED Your Business!!! ✨NEW VIDEOS Every Week✨ Subscribe: https://bit.ly/2J0er7F I often get questions from veterans and military families that are curious about starting a business, have an idea or want to chase their passion but they don't know how to start. As an ARMY Veteran myself, I have chased my own hobbies and interest to start and launch my own journey as a serial veteran entrepreneur. Entrepreneurs are confident, positive, creative, resourceful, and resilient people who are faced with a problem and works out the solution. In today Founders TIME Podcast episode #5, I had a very interesting conversation about the meaning and importance of Quality in Business with our guest speaker Diane Elko, MBA. She is the Founder of Improve It! Consulting & Training and a certified Lead Auditor for ISO 9001 and experienced consultant for 14001. Consumers' perceptions of product or service quality are influenced by various factors at each stage of the buying process. Because quality is more than making a good product or providing a good service. Customer perceptions often ties the quality of a product or service to reliability, durability, and workmanship for a company. Diane and her team coach business leaders on how to reach their highest level of performance. Achieving award-winning results, she has been implementing the Performance Model For Success™ with small and mid-sized to Fortune 500 businesses across all industries. Gain your customer confidence by improving and implementing quality practices in your business.

CIRCULATION & Natural Ways to Improve It with Susan Smith Jones, PhD Your circulatory system, also known as your cardiovascular system, is made up of your heart and blood vessels. It works to transport oxygen and other nutrients to all the organs and tissues in your body. It also works to remove carbon dioxide and other waste products. Having a healthy circulatory system is vital to your health and well-being. What can we do to keep our heart and blood vessels in good shape. Well, that’s our topic today and holistic health and lifestyle expert, Susan Smith Jones, PhD, will share some of her surefire tips. Susan Smith Jones has made extraordinary contributions in the fields of well-being, anti-aging, optimum nutrition and balanced living. A frequent radio/TV talk show guest and motivational speaker, Susan is also the author of many books on holistic health and optimum vitality, including her latest celebrated book —WIRED FOR HIGH-LEVEL WELLNESS: Simple Ways to Rejuvenate, Meditate & Prosper www.SusanSmithJones.com http://www.bluefunkbroadcasting.com/root/twia/ssj86.mp3

Imagine making all those concerns on public speaking, pitching, cold calling, customer ranting, and network building, all magically go away. Now, instead of wishing them away, imagine doing something that will make them all much easier, because they are and will remain part of our everyday life. This is exactly what improvisation does! Not only does improv help you think quickly when in a tricky situation but also improve team spirit and cohesion.   In today’s episode of the Abundantly Clear podcast, Malorie speaks to Erin Diehl, founder of Improve It! Erin’s company is on a mission to provide high-energy, laughter-filled, corporate performances and team-building workshops that feature professionally-trained improvisers. Improve it!’s corporate performances have teams roaring with laughter and their highly-interactive workshops enhance the team’s cohesion and communication skills. Tune in for a wake-up call on why companies should create a friendlier, more collaborative atmosphere in the workplace through improv.    You’ll learn:    How Erin piloted and actualized the idea if starting Improve It! How Erin’s company helps to develop relationships, enhance trust, and network with people  How to use experiential learning to help people be their true self  The connection between Erin’s life, improv, and the work she does around helping people overcome failure How the pandemic affected  Improve It! and how they successfully pivoted and so much more!   Favorite Quote:   My purpose is to serve people with a smile. And I want them to come to me and have a conversation and leave feeling lighter and better.    -  Erin Diehl   Connect with Erin:   Website: www.learntoimproveit.com Podcast: The Failed It! Podcast Instagram: learntoimproveit LinkedIn: improve it! LLC Facebook: improve it Twitter: @learn2improveit   How to get involved Malorie has become an expert in helping people remove their mindset blocks, so they can experience the growth in their business and decrease in stress they desire. Check the site to learn more, download a freebie and stay connected. If you liked this episode, take a moment to subscribe on Apple Podcasts and post a review, or visit us here - and be sure to check out episodes 57, 63 and 24 to hear more from Malorie’s clients!  

Listen to this podcast, to learn more on how Nutanix HCI can: •Reduce the physical footprint of legacy datacenter infrastructure •Increase and leverage underutilized resources •Improve IT security posture •Modernize environments for the cloud era

This is episode 47,  “The U.S. Pandemic Response and How to Improve It.”  My guest, James G. Kahn, MD, MPH, is Emeritus Professor in the Philip R. Lee Institute for Health Policy Studies, the Institute for Global Health Sciences, and the Department of Epidemiology and Biostatistics at the University of California, San Francisco. He has published widely on the cost and cost-effectiveness of HIV prevention and treatment in the developing world, as well as on other health conditions.  Dr. Kahn researches and educates on the costs and financing of single payer / Medicare-for-All. In 2005, he quantified that U.S. health care administration costs funded through private insurance account for nearly 25% of the costs of physician and hospital care. In 2014, he led a team that estimated potential savings of at least $400 billion per year from simplifying insurance-related administration in the U.S.  Dr. Kahn also served for two years as President of the California chapter of Physicians for a National Health Program. Do not miss the episode as Dr. Kahn discusses our response to the pandemic and how we can improve our response in the future.

One wag called it a ‘conservationist rom-com’, when the big personality of Theordore Roosevelt came into contact with the big hole, The Grand Canyon. It was there that he spoke the words which became the title of David Gessner’s new book, ‘Leave It As It Is’. Yet, it seems that Americans can’t leave well enough … Continue reading EP 403 Leave It As It Is: You Can’t Improve It

Purity of Heart: How to Improve It

You absolutely have to love a woman who practically launched her business on a dare and regularly celebrates failure! As the founder of Improve It! Erin Diehl specializes in using improvisational training to improve employee performance in more categories than you would think possible. Talk about being an expert in helping folks get out of their own way! And if that weren’t enough, her podcast, Failed It! continues down the path of the benefits of not taking ourselves too seriously and understanding that you must fail in order to improve.Resources:WebsiteLinkedIn

Join me on LinkedIn Live Broadcast "Powering Unique You" with Diane Elko.Diane Elko is passionate about IMPROVEMENT and CHANGE! She is the owner and President of Improve It! Consulting & Training, with extensive experience leading, motivating, and coaching executives and teams toward successful results. Diane has spoken at conferences nationwide and published numerous articles on Quality Management and Creative Team Problem Solving. Her focus is on the customer, and she combines this with helping small business owners achieve the significant results they deserve using practical, measurable, and straightforward systems.Topic: How Focusing On Quality Can Improve Your Career And BusinessWe will cover:

This week we start our morning with positivity and light Chief Edutainment Director Erin Diehl, Founder of Improve It! We spiked our brew of coffee with a gift of Maple Bourbon from Smuggler's Notch Distillery in Vermont. We laugh about our days living out of a suitcase and being official pee security of Spring Break experiential sites on Panama City Beach, FL. We talk about failure, controlling attitude & effort, and leaning into a new virtual community! www.smugglersnotchdistillery.com www.mry.com www.learntoimproveit.com

How did we get to a place where life's become an endless treadmill of work? In her latest book, Can't Even: How Millennials Became the Burnout Generation, Anne Helen Petersen tackles this question. Her book is for anyone who feels their life has become an endless to-do list. In particular, Petersen describes the plight of today's millennials, a generation she believes is under constant pressure to perform. She explains how, for many millennials, it begins in childhood, when activities originally intended for fun get repurposed for resume building. She argues, "You're taking things that are meant to be leisure, that are meant to be those joyful corners of your life that are not work, and you're turning them into work." Petersen discusses the social and economic forces that have led to this cultural shift, including the demise of labor unions, increasing reliance on contract workers, and the rise of the gig economy. In each case, she points out how companies benefit, while workers struggle to make ends meet. At the same time, she wonders if millennials are the generation that can break the cycle. She muses, "I'm curious if we can refigure our relationship to work. I am curious if millennials are broken, if we are just too far down this road, or if we can take a different road." Anne Helen Petersen is a senior culture writer for BuzzFeed. A former academic, she received a Ph.D. at the University of Texas at Austin, where she focused on the history of celebrity gossip. Her previous books, Too Fat, Too Slutty, Too Loud and Scandals of Classic Hollywood, were featured on NPR, Elle, and The Atlantic. Curious Minds Team Learn more about creator and host, Gayle Allen, and producer and editor, Rob Mancabelli, here. Episode Links The Remix: How to Lead and Succeed in the Multigenerational Workplace by Lindsey Pollak How Millennials Became the Burnout Generation by Anne Helen Petersen Annette Lareau Temp: How American Work, American Business, and the American Dream Became Temporary by Louis Hyman The Fissured Workplace: Why Work Became So Bad for So Many and What Can be Done to Improve It by David Weil The Effects of 'Clopening' on Employees: What Employers Can Do by Tom Starner Are You Just LARPing Your Job by John Herrman How Does Your Ugly Garden Grow? by Anne Helen Petersen Ways to Support the Podcast If you're a fan of the show, there are three simple things you can do to support our work: Rate and review the podcast on iTunes or wherever you subscribe. In the next week, tell one person about the show. Subscribe so you never miss an episode. Where to Find Curious Minds Spotify iTunes Tunein Stitcher Google Podcasts Overcast

This week's episode is a conversation I have with one of my favorite humans, entrepreneurs, and fellow Chicago improvisers, Erin Diehl.  She owns an improv training company called "Improve It" and her podcast is called "Failed It", which is all about embracing failure.  My favorite!!! In this episode, you'll get to hear about my failures, my mistakes, and how I came to the fear boss mindset. This episode digs into: * Entrepreneurship and building a business * Shit shields and how to get one * The improv mindset * Perfectionism * And so much more! Find all the show notes, downloadables, links, and good vibes at www.judiholler.com/podcast ( http://www.judiholler.com/podcast ).

"We're really focused on revenue growth right now, so we're not as focused on core values."Believe it or not, that's actually what a lot of companies tell their employees.But what good are your core values if you only value them when it's convenient?Erin Diehl's business improv training company Improve It! is a graduate of the Goldman Sachs 10k Small Businesses program and has worked with the likes of Kellogg's, United, Pepsico, Groupon, Motorola, and more.They haven't come this far by tabling their values.In fact, they've done the exact opposite and built all of their KPIs around them.Erin steps to the mic and explains Improve It's process as well as how they've continued to live by their values even when a pandemic throws everything off.Find Erin online:Instagram: @keepinitrealdiehlLinkedIn: linkedin.com/in/erindiehlFind Improve It! online:Instagram: @learntoimproveitwww.learntoimproveit.com Today's episode is brought to you by Sales Hacker. The world's smartest community of forward-thinking B2B professionals. Grab their latest expert-created articles, webinars, and podcast episodes at www.saleshacker.comPLUS -- hear from me and 40+ other leading sales professionals this summer in the Blissful Prospecting Think Outside The Script summer virtual tour! All talks are live and interactive, sign up at tour.blissfulprospecting.com. See acast.com/privacy for privacy and opt-out information.

In today's episode, Diane Elko, Owner at Improve It Consulting and Training about why it is important to treat others with respect and why team building is so crucial to the success of both personal and business relationships. She speaks about the Heart of Business and  she opens up about the topic of feeling out of control during these trying times in the world today.  You will hear her share her 4-step proprietary process (Map It, Own It, Improve It, Measure It)  and speak about it is so important to help one another in business.To learn more about Diane Elko and her business please visit her at https://improveitsolutions.com or email her at dmelko@txun.netTo check out what Nelia Hutt has been up to visit www://travellivegive.com

Maximum Volume/Flex Your Head Show #40 originally aired on Radio-WIGWAM (2017-11-07)1. Maximum Volume/Flex Your Head Show Radio-WIGWAM Promo / Max Volume 2. Missionimpostheme Intro / Max Volume [2017]3. No Rock Stars - DOWC / Max Volume [2012]4. Maximum Volume/Flex Your Head Show #40 Intro / Max Volume 5. She's In Love With A Rock N Roll Girl / The Cheap Dates Piss Away Another Goddamn Year  [2015]6. Attention - DOWC-1 / Max Volume [2017]7. Heavy Metal Handicap / The Hypotheticals Eye of the Mongoose  [2017]8. Stab Into My Back / Jizzlobbers You Better Do What Your Mama Says!  [2017]9. Your Vocabulary - How to Improve It - 1940's -1 / Max Volume [2017]10. Who Invited You / Nobodys Hussy  [2016]11. The Outlaw Josey Wales / No Flow For The Love: Volume Three  [2017]12. EL DIABLO SOY / Apestosos Con Los Huevos al Plato  [2017]13. Floating Awkwardly / Angry Skeletons Slightly hostile/Real friendly  [2017]14. Your Vocabulary - How to Improve It -2 / Max Volume [2017]15. What? / Clem Darling and the Astronauts Whatever Major Loser  [2017]16. Accidentally in Love (Counting Crows) / Why Everyone Left Tell Your Friends Pop Punk Not's Dead:  September 2017 Summer Sampler  [2017]17. Words I Should Have Swallowed / Windsor Diets Words I Should Have Swallowed  [2017]18. Aspartame / Justice Denied For The Love: Volume Two   [2014]19. Your Vocabulary - How to Improve It -3 / Max Volume [2017]20. Idling Engines / The Fur Coats Short Brain  [2015]21. Need You / Sharp Sleeves Tell Your Friends Pop Punks Not Dead - October 2017 Fall Sampler  [2017]22. Wasted Ambition / Rational Anthem Whatevermind  [2013]23. Metalscore / One Man Down Alpha  [2012]24. Your Vocabulary - How to Improve It -4 / Max Volume [2017]25. Wasting My Time / THICK It's Always Something..[2016]26. No Lo Supe Arreglar / Cid Campeador CID  [2017]27. The Saint / The Mongrels 4383  [2015]28. Bug Zapper / Blood Cookie New Empty Your Mind  [2017]29. Your Vocabulary - How to Improve It -5 Max Volume [2017]30. Incinerator / Bobby Jackson Demo 1: Shinichi Kudo  [2017]31. Same Old / Alvin and the Angry Barrels Self Titled EP  [2017]32. First Attempt / Might've Beens Unwanted/Unreleased  [2012]33. Goin' Loco / Cho Loco Feat. Forty Ounces For The Love: Volume Two   [2014]34. Your Vocabulary - How to Improve It -6 Max Volume [2017]35. Planned Obsolescence / Angry Skeletons Slightly hostile/Real friendly  [2017]36. Sex, Drugs, Sex and Rock & Roll" / Nobodys Hussy  [2016]37. Fuck Up / Corndog Skateboard For The Love: Volume Three  [2017]38. Louie Barletta / UFF Hoy Vas a Planchar  [2017]39. Your Vocabulary - How to Improve It -7 Max Volume [2017]40. Nothing / Clem Darling and the Astronauts Whatever Major Loser  [2017]41. Boring Metaphors / Blood Cookie New Empty Your Mind  [2017]42. Purgatory / The Mongrels 43 83  [2015]43. 25 Minutes / The Stray Adventures For The Love: Volume Three  [2017]44. Your Vocabulary - How to Improve It -8 Max Volume [2017]45. Abril / Bobby Jackson Demo 1: Shinichi Kudo  [2017]46. Cool Kids (Screeching Weasel Cover) / It Gets Worse For The Love: Volume Three47. Rocks / Clem Darling and the Astronauts Whatever Major Loser  [2017]48. Kemare 2 / Apestosos Con los huevos al plato  [2017]49. One Drink / The Mongrels 4383  [2015]50. Your Vocabulary - How to Improve It -9 Max Volume 51. Fuck Nazi Scum / Windsor Diets Demo 2017  [2017]52. Flex Your Head / Max Volume/Ian McKaye   [2017]©Max Volume Media, Co., Ltd  /  ©Maximum Volume Records  /  ©Anti-Pop Productions

In this podcast, Robert Giugliano, MD, SM, discusses his latest analysis of IMPROVE-IT data, which compared simvastatin-ezetimibe combination therapy with simvastatin monotherapy among patients aged 75 years or older who had had acute coronary syndrome. He also explains which patient groups benefitted the most from ezetimibe add-on therapy. More at: www.consultant360.com/cardiology.

In this podcast, Robert P. Giugliano, MD, discusses the safety and efficacy findings from IMPROVE-IT, the practical implications for ezetimibe, and more. More at: www.consultant360.com/cardiology.

Maybe you wish you had more comedy in your workplace, or just an easier way to talk to your co-workers about projects. Erin Diehl of Improve It! is part professional comedian, part corporate trainer -- and combines those skills to bring people together for a better day at the office. She joins the BrandBuilders Podcast for a unique play on office culture.

Bringing a purpose to a team can bring them new vitality. When they know where they work and why they work, they can deliver the Core Values of an organization to the daily life of the company and even out into the world. So what is the best way to streamline the implementation of Core Values to a company? The Core Chart is an excellent visual representation of the Core Elements which can bring the Core Values into a single place for team members to see. The Core Values, the Core Purpose, and the Core Workflow can all be brought together with clarity, represented visually. Employees can know exactly what they are doing and why with respect to the Core Values of a company. This week Will Scott joins Jeremy again to discuss the ins and outs of Will’s book The Culture Fix. They discuss how to deliver your Core Values to your team and the daily life of a company, the example of Improve It!, and the useful tool Will created to help any organization develop their Core Values. Here’s a glimpse of what you’ll learn:   [01:41] Bringing a purpose to a company so that people love where they work, and why they work [03:09] The example of Improve It! And how they help people find better versions of themselves [04:30] How you can find the essense of a Core Value within the daily activities of a company through the example of Improve It! [06:45] How improving a culture can have a positive impact on the personal lives of the people in a company [07:30] The Core Chart: why Will likes to bring a visual element to communicating Core Values [09:00] Real-world examples of the Core Chart from Will’s clients [10:30] The Core Values Workbook: what is contained in the workbook which is free from cultureczars.com Resources Mentioned in this episode The Culture Fix Connect with Will About Me Culture Czars Linked In

Dr. Mike Miedema, a preventive cardiologist with the Minneapolis Heart Institute, discusses cardiovascular disease (CVD) prevention, including current uses of aspirin and diabetic agents for primary CVD prevention.  Dr. Miedema also discusses current changes in recent cholesterol guidelines. Objectives: Upon completion of this CME event, program participants will be able to: Describe current optimal use of aspirin for primary cardiovascular disease prevention. Express their understanding of novel diabetic agents used for CVD prevention. Explain changes in the recent cholesterol guidelines. CME credit is only offered to Ridgeview Providers for this podcast activity. Complete and submit the online evaluation form, after viewing the activity.  Upon successful completion of the evaluation, you will be e-mailed a certificate of completion within 2 weeks.  You may contact the accredited provider with questions regarding this program at rmccredentialing@ridgeviewmedical.org. Click on the following link for your CME credit:  CME Evaluation: A 2018 Cardiovascular Prevention Update - CME Enduring Activity (**If you are listening to the podcasts through iTunes on your laptop or desktop, it is not possible to link directly with the CME Evaluation for unclear reasons. We are trying to remedy this. You can, however, link to the survey through the Podcasts app on your Apple and other smart devices, as well as through Spotify, Stitcher and other podcast directory apps and on your computer browser at these websites. We apologize for the inconvenience.)  The information provided through this and all Ridgeview podcasts as well as any and all accompanying files, images, videos and documents is/are for CME/CE and other institutional learning and communication purposes only and is/are not meant to substitute for the independent medical judgment of a physician, healthcare provider or other healthcare personnel relative to diagnostic and treatment options of a specific patient's medical condition.”   FACULTY DISCLOSURE ANNOUNCEMENT  It is our intent that any potential conflict should be identified openly so that the listeners may form their own judgments about the presentation with the full disclosure of the facts. It is not assumed any potential conflicts will have an adverse impact on these presentations. It remains for the audience to determine whether the speaker’s outside interest may reflect a possible bias, either the exposition or the conclusions presented. Planning committee members and presenter(s) have disclosed they have no significant financial relationship with a pharmaceutical company and have disclosed that no conflict of interest exists with the presentation/educational event.     Show Notes:   We were fortunate to be joined by Dr. Michael Miedema on December 14, 2018 to discuss cardiology updates and how they are about to impact our practice, if not already. He is a board certified cardiologist, and senior consulting cardiologist and principal investigator with MHI. He trained in medical school at U of M, then went on to an internal medicine residency at Abbott Northwestern, with his cardiology fellowship to follow at the University of Minnesota.  He went on then to another fellowship in cardiovascular prevention at Harvard, in addition to earning his Masters in Public Health. He happens to also be on the committee for the ACC/AHA 2019 Guidelines for the primary prevention of cardiovascular disease. And despite the fact that he grew up in rural Minnesota, this midwesterner speaks as fast as any east-coaster I’ve ever met! So whether you’re in your car,  operating your snowblower or starting that crossfit New Year's resolution , enjoy the knowledge that’s about to be dropped by our very esteemed colleague, Dr. Mike Miedema.   Aspirin: should people take aspirin for primary prevention of heart attack and stroke? We used to say, probably yes!  In the ASCEND trial (New England Journal) in the fall of 2018, Low dose aspirin was looked at and in 7.5 years there was approximately a 12% reduction in major CV events, however serious bleeding was increased by 29%. Not a simple nose bleed, but hospitalization type bleeding.    Another trial, ASPREE in the NEJM also in the fall of 2018, looked at older patients without CV disease, above age 70, taking low dose aspirin for 5 years. It showed no benefit again in overall CV risk, but bleeding risk was increased signficantly, by 38%. In fact all cause mortality showed an increase in cancer in this group, which is interesting. At the very least, the study showed no improvement in cancer risk.   Another trial published in Lancet, the ARRIVE study, consisted of 12000 patients. They were kept on ASA low dose for 5 years, and once again no improvement in the aspirin group was shown. However, the calculated risk was about twice what their actual risk was. The bleeding risk once again was higher.  Rates of MI actually demonstrated no change in the aspirin group.    The Physicians Health Study looked at a primary outcome of MI. It showed that ASA prevented the outcome of MI. Later the investigators tried to expand the outcomes of the study to include CV deaths in general. Unfortunately this now diluted the effect of aspirin and in other words, aspirin’s effect on preventing all cause CV death, like aortic dissection, etc., which makes aspirin look less effective. In addition, there is the issue of these trials looking at “intention to treat” which relates to an inherent bias toward the intervention arm, which didn’t account for the people who had to pull out the trial.  The double edged sword is that many people do in fact pull out of the trials and are still included in the trial results, which skews the results as well.    To conclude, aspirin is likely not helpful if you’re over age 70.  Essentially, if you’re at low CV risk or increased bleeding risk, you probably also shouldn’t take it. Between the ages of 40 and 70, patients may benefit from aspirin therapy, although not without risk of bleeding.      Cholesterol: One month ago, ACC/AHA updated the cholesterol guidelines from the 2013 version. In 2013, statins were recommended for primary and secondary prevention.  Secondary prevention includes lifestyle modifications.  There has been a movement to stratify people into not high risk and higher risk.    With regard to secondary prevention, the Improve-It trial was reanalyzed. The initial trial looked at ezetimibe with and without a statin.  Over 7 years and 18000 patients, there was  a 2% reduction in risk for CV disease. Cholesterol went down by 20%. Risk scores were calculated when the study was reanalyzed. Only half the trial had zero to 1 of the usual risk factors, and there was no benefit in this group. And in this group over the 7 years, there was no benefit from ezetimibe. In 25% of the trial, there was a benefit, but these people had 3 or more risk factors. Consequently, this group saw the most improvement and benefit. Essentially, if you’re not at high risk, a statin is sufficient. Ezetimibe can be considered in this group if the statin does not get you below an LDL of 70.  Otherwise, if you decide not to add ezetimibe, a maximally tolerated statin is appropriate. Older than age 75?  A statin can be offered but not mandatory. The very high risk group, however, meaning a major CV event (ACS, MI, Stroke or symptomatic PAD) history, along with at least one other risk factor, the LDL goal must be less than 70.  Statin therapy, along with ezetamibe is warranted, and if this doesn’t work, a PCSK9 inhibitor is indicated as well. These are expensive meds, though. Ezetimibe is not very expensive and tolerated well, so if that LDL can’t get below 70, it should really be added in this group.   Regarding primary prevention, familial hypercholesterolemia should be screeened for.  An LDL > 190 should be on a statin. No other risk factors are needed. People with type2 DM should be on a statin as well. Greater than age 75? Risks must be weighed, but statin is optional. Age 0-20, lifestyle, FH screening. 20-39, if LDL > 160 and/or a calculated greater lifetime risk, a statin can be offered. Plaque is much more regressable in earlier rather than later stages. A trial is currently under way looking at this concept, attempting to treat people in their 30s. This is the Cure Athero trial which is ongoing.  For age 40-75 with ldl between 70-190, if risk is less than 5%, no intervention besides lifestyle is indicated. With a calculated risk of >20% they should be on a statin.  If somewhere between low and high risk, there are other risk enhancers that should be looked at, i.e. family hx, inflammatory diseases, ethinicity, etc. If the calculated risk is 7.5 to 20%, a statin should be offered, but if there is uncertainty about whether to treat, a calcium score should be obtained. In fact, this is one of the major guideline changes, in that calcium scoring should be looked at. If the score is 0, then no therapy should be used. Scores between 1-99, statin should be offered, but 100 or greater, statin is indicated.  This concept was from a paper published in JACC in 2015.  Again, Ca++ scoring is best used in the group with intermediate risk between 7.5 and 20%.  Following the cholesterol is also advised. In fact, fasting lipid panels are not required. The panel can now be done non-fasting. Trial data has also shown that statins are very safe. Over 20 years, cancer, dementia and other theorized health risks were debunked.  Coenzyme Q10 use, and monitoring CPK, ALT/AST on asymptomatic patients are not indicated.  To summarize, people with known CV disease should be on a high intensity statin with goal LDL < 70, ezetimibe and PCSK9 added if at high risk. Also, if FH, consider adding ezetimibe and PCSK9, goal < 100. DM? Moderate intensity statin, higher if at high risk. Primary prevention? Moderate intensity statin, high intensity if high risk. If risk is uncertain, do a Calcium score.  Another trial is ongoing looking at fish oil (EPA and DHA).  EPA (vasepia) the purified variety ("fish oil on steroids"), is implemented in the mildly elevated TG population. Over 5 years, this medication along with statin therapy showed a reduced risk 25% reduction and 5% absolute risk reduction. Strangely, if your TG are in the 1000s, you are not at higher CV risk, but when they are mildly elevated, there is more atherogenicity. Essentially, if you have mildly elevated TG, you may benefit from this treatment. Expense and dosing is an issue, but this must be a considered therapy.    Diabetes: Cardiologists are becoming more engaged in DM care once again. The vast majority of DM is type 2. 1/3 of adults in this country are pre-diabetic. The risk of MI and stroke is significantly greater in diabetics and lifestyle really matters most with diabetics as well.  A recent paper in JACC demonstrated the significant benefit in lifestyle improvement.  The UKPDS trial looked at lifestyle vs. insulin vs. metformin.  Metformin showed substantial benefit in diabetes related events and diabetes related death. If metformin is started before insulin, a significantly lower Hgb A1C and lower BMI is seen. Type 2 DM is a disease of insulin sensitivity, not deficiency. Insulin is a storage hormone and does lead to weight gain. Metformin is recommended therefore as first line for type 2 DM, based on studies in the 90s and early 2000s. They showed improvement in Hgb A1C, but CV risks really weren’t shown to improve.  Based on 3 large trials in 2010 (ADvance trial, a VA trial and the Accord trial) no significant reduction in CV events was shown. In fact a slight increase in all cause mortality was shown. This was in people with more intense glucose control. Weight gain was a significant issue in aggresive Hgb a1c treatment group.   There a two relatively new medications: sglt2 inhibitors and the glp1 agonists. The sglt2s basically block the  pulling of glucose from the urine back into the blood stream. This lowers the HgbA1C. It also has a natriuretic/diuretic effect as well. There is very little risk of hypoglycemia with this drug as well. It is also a natriuretic. In 2015, a trial looking at this class of med revealed a 14% reduction in MACE.  CV death showed a 38% reduction. Most of the benefit was in patients with risk of heart failure.  Another trial also showed a 33% reduction in heart failure hospitalizations.  The largest trial though of 17000 patients was a primary and secondary prevention trial. Similar benefts were noted, but also a renal benefit. Ultimately, our type 2 DM patients should have these medications considered for both primary and secondary prevention. GLP1 receptor agonists or glutides, are also an option. This medication class causes less glucose production by the liver, more uptake by the muscles and delayed gastric emptying. Weight loss may occur with this med. CV effects include decreased inflammation and decreased risk for clotting in the smaller vessels. Overall reduction in Hgb a1c, weight loss, improved LDL, decrease in BP and decreased inflammation. 13 to 14 % reduction in MACE was noted with this, especially in stroke and atherosclerosis. Not so much with CHF due to an anti-atherosclerotic mechanism.  Glutides are given once weekly. Yeast infections are more common with the SGLT2s due to increased glucose in the urine.  ACC constructed a pathway for use of these various medications:  Essentially, For your DM pts with CHF, an SGLT2 should be given, and a GLP1 for DM pts with previous CV events. Cost is also an issue with these meds; however they can be used together.   CV genetics considerations and screenings is an up and coming topic.  The Framingham study said CV disease is due to multiple-factorial processes and risk factors. Therefore it is hypothesized that mutliple genes may lead to higher risk.  If your lifestyle is good, even if you have increased genetic risk, you can substantially lower your risk. In about 2% of the population, an FH gene can be found.  If you have this gene, your risk is higher than others at a similar cholesterol level, and for a longer period of your life of course. Therefore it is important for these patients to address this with medication and lifestyle.  Adding the genetic risk score to your overall basic CV risk factors will help to predict your actual CV risk.  This risk calculation and stratification is still being studied and looked at.   ACC/AHA Risk calculator link: cvriskcalculator.com   In summary:    ASA for primary prevention probably shouldn’t be used. Select high risk patients are okay, but avoid in the elderly.  Cholesterol:  Statin plus ezetemibe and pcsk9 for higher risk, and Ca score for  those uncertain about their risk.  DM: use the new meds with type 2 DM at high CV risk.  Genetics: not quite ready for prime time, but we need to look into this more and get ready for patients desiring this in the future.  Again, a big thanks to Dr. Miedema for joining us and for providing this cardiology update. Ridgeview appreciates his expertise, his ongoing dedication to his patients and to the cardiology specialty.

On this episode of Fault Lines, guests join hosts Garland Nixon and Lee Stranahan discussing the violence on the Middle East. Did moving the US Embassy to Jerusalem exacerbate tensions? Are there any viable solutions to this decades-old conflict?The hosts and guests will report on the deadly explosion at an Orange County, California medical facility. They will also feature important news the mainstream media won't cover and analyze recent developments including the Iraqi elections, primary elections in the US, the Senate Vote on Gina Haspel for CIA Director, and how to improve Medicare, as well as other un- and under-reported news in the “Divided States of America.”Scheduled guests and topics:Baxtiyar Goran - Reporter for Kurdistan 24 | Topic: Results of the Iraqi Elections w/ @BaxtiyarGoranLesley Clark - National Correspondent for McClatchy DC | Topic: Primary Results and Senate Vote on Gina Haspel for CIA DirectorAriel Gold co-director of Code Pink Topic: Gaza, Israel, US Embassy dedication Mark Frost Topic: The economics of sports bettingDr. Bill Honigman MD ER Physician, Healthcare reform expert, topic: How Medicare Works and Ways to Improve It

On this episode of Fault Lines, guests join hosts Garland Nixon and Lee Stranahan discussing President Donald Trump's decision to withdraw from the agreement between the U.S., the U.K., France, Germany, China, Russia, and Iran to halt Iran's nuclear program is already having repercussions. Was the agreement working? Is Trump's decision to scrap the deal in the best interests of the U.S.? Will it lead to a more stable region and planet, or is it making conflict more likely?The hosts will also ask guests questions the mainstream media won't ask and cover the news the MSM won't cover about the Japan-China-South Korea Trilateral Summit, healthcare, the Gina Haspel for CIA Director Senate Hearings, and other un- and under-reported news and issues in the “Divided States of America.”Scheduled guests and topics:Matt Stiles - LA Times Special Correspondent in Seoul, South Korea | Topic: The Japan-China-South Korea Trilateral SummitDr. Annette Bosworth, MD internist; Author “Any Way You Can” | Topic: Proper Skin Care Elizabeth Vos | Topic: Ray McGovern at Gina Haspel for CIA Director Senate HearingsDr. Bill Honigman MD ER Physician, Healthcare reform expert, topic: How Medicare Works and Ways to Improve It

Dr Carolyn Lam:                Welcome to Circulation On The Run, your weekly podcast summary and backstage pass to the journal and its editors. I'm Dr Carolyn Lam, associate editor from the National Heart Center and Duke National University of Singapore.                                                 This week's journal features two papers. One a research letter and the second an original article, both focusing on the effect of ionizing radiation on interventional cardiologists. I'm sure that cuts close to the heart, so please stay tuned. Coming up right after these summaries.                                                 The first two original articles in this week's journal describe a metabolic adaptation that is good for the abnormal cell but bad for the patient. This is a shift in glucose metabolism called the Warburg phenomenon where there is failure of two fundamental pathways. Number one glucose metabolism and number two mitochondrial oxygen sensing. This Warburg phenomenon enables a reliance on glycolysis despite an abundance of available oxygen. These two circulation articles uncover new players in the Warburg phenomenon, both in the setting of pulmonary arterial hypertension. One in the pulmonary arterial endothelial cells, and the second in fibroblasts.                                                 In the first paper, first and corresponding author Dr. Caruso and co-corresponding author Dr. Morrell from the University of Cambridge examined the microRNA and proteomic profiles of blood outgrowth endothelial cells from patients with heritable pulmonary arterial hypertension due to mutations in the bone morphogenetic protein receptor type two, or BMPR2 gene, and in patients with idiopathic pulmonary arterial hypertension. They demonstrated that reduced expression of microRNA-124 in pulmonary arterial hypertension endothelial cells was responsible for the dysregulation of the splicing factor polypyrimidine tract binding protein 1, and its target pyruvate kinase M2 or PKM2, which is a major regulator of glycolysis and which contributes to abnormal cell proliferation. Reduced BMPR2 levels were associated with reduced microRNA-124 expression.                                                 In the second paper first author Dr. Zhang, corresponding author Dr Stenmark and colleagues from the University of Colorado studied pulmonary adventitial fibroblasts isolated from cows and humans with severe pulmonary hypertension. PKM2 inhibition reversed the glycolytic status of pulmonary hypertension fibroblasts, decreased their cell proliferation and attenuated macrophage interleukin beta expression.                                                 Normalizing the PKM2 to M1 ratio in pulmonary hypertension fibroblasts by using microRNA-124 over expression, or by PTBP1 knockdown, reversed the glycolytic phenotype, rescued mitochondrial reprogramming and decreased cell proliferation. Finally, pharmacological manipulation of PKM2 activity or treatment with histone deacetylase inhibitors produced similar results. These findings provide new avenues for the treatment of pulmonary arterial hypertension and are discussed in an accompanying editorial by Stephen Archer from Queen's University in Ontario Canada.                                                 The next paper tells us that the addition of ezetimibe to simvastatin in patients stabilized after acute coronary syndrome reduces the frequency of ischemic stroke, with a particularly large effect seen in patients with a prior stroke. First and corresponding author Dr. Bohula and colleagues from the TIMI study group investigated the efficacy of the addition of ezetimibe to simvastatin for prevention of stroke in the IMPROVE-IT trial where post ACS patients were randomized to placebo and simvastatin or ezetimibe and simvastatin and followed for a median of six years.                                                 The current study focused on patients with a history of stroke prior to randomization. The authors found that the addition of ezetimibe to simvastatin reduced the frequency of ischemic stroke with a hazards ratio of 0.79, with a particularly large effect seen in patients with a prior stroke, where the hazards ratio was 0.52, compared to patients without a prior stroke where the hazards ratio was 0.84. Hemorrhagic strokes were rare and a non significant increase in hemorrhagic stroke was observed with the addition of ezetimibe. Thus, the authors concluded that it is reasonable to consider the addition of ezetimibe, a generic lipid lowering therapy with an acceptable safety profile, to a moderate to high intensity statin regimen for the prevention of ischemic stroke in patients with established ischemic heart disease, with or without a prior stroke.                                                 Atrial fibrillation is the most common sustained arrhythmia in hypertrophic cardiomyopathy, but the influence of atrial fibrillation on clinical course and outcomes in hypertrophic cardiomyopathy had remained incompletely resolved. That is until today's paper in circulation. First and corresponding author Dr. Rowin and colleagues from Tufts Medical Center accessed the records of 1,558 consecutive patients followed at the Tufts Medical Center hypertrophic cardiomyopathy institute for an average of 4.8 years from 2004 to 2014.                                                 20% of patients had episodes of atrial fibrillation, of which 74% were confined to symptomatic paroxysmal atrial fibrillation, while 26% developed permanent atrial fibrillation. They found that the timing and frequency of paroxysmal atrial fibrillation events were unpredictable with an average two year interval between the first and second symptomatic episodes but progressing to permanent atrial fibrillation uncommonly. They further found that atrial fibrillation was not a major contributor to heart failure morbidity, nor a cause of arrhythmic sudden death, and when atrial fibrillation was treated it was associated with low disease related mortality, no different than for patients without atrial fibrillation. Finally, atrial fibrillation was an uncommon primary cause of death in hypertrophic cardiomyopathy, but this was virtually limited to embolic stroke, thus supporting a low threshold for initiating anticoagulation therapy.                                                 That warps it up for our summaries. Now for our feature discussion. This week's journal carries two papers that refer to the health risks of ionizing radiation to interventional cardiologists. Yes, you heard me right. You're going to want to listen up. These are going to send chills up our spine, or rather maybe chills into our brains and into our blood according to the papers.                                                 To discuss these two papers I have with us associate editor from UT Southwestern, Dr. Manos Brilakis, as well as the corresponding author of the first paper Dr. Maria Andreassi from CNR Institute of Clinical Physiology from Pisa Italy. Maria, could you start us off by telling us what you found in your research letter? Dr Maria Andreassi:        In our study we evaluated the circulating microRNA profile in interventional cardiologists in order to provide insights into the molecular and the biological situation and the underlying association between occupational low dose radiation exposure in cath lab and the potential long term disease risk. The hypothesis of our study was based on the evidence that the microRNAs are crucial regulators of gene expression. And they have been shown to be dysregulated in many human disease. Moreover, the stability and the tissue selectivity of circulating microRNAs make them ideal biomarkers to explore disease potential clinical disease risk.                                                 In summary, our findings exhibited the dysregulation and the down regulation of acute specific circulating microRNA, the brain specific microRNA-154 and the microRNA-2392. This tells us significantly involved in the deregulation of the three brain pathways and the brain cancer pathway as demonstrated by systematic analysis. In particular, the dysregulated labels so the brain specific microRNA-154 in interventional cardiologists support the notion that the brain damage is one of the main potential long term risk on unprotected head radiation in interventional cardiologists with possible long lasting consequences on the cognitive function. Dr Carolyn Lam:                That is really striking. Brain specific microRNA was shown to be dysregulated in interventional cardiologists compared to controls who were not exposed to radiation. As I understand it, these dysregulated microRNAs can be seen in certain forms of epilepsy and Alzheimer's disease and certain brain cancers and so the concern is very obvious for those of us who are interventional cardiologists. But your study did not actually relate these two specific adverse events. Is that correct? Dr Maria Andreassi:        You're right. Yes. microRNA-154 was first identified as a brain specific microRNA which is involved with inner synapse development and the directly implicated in [inaudible 00:12:15] and memory. Additionally, decreased expression of this microRNA class, was previously reported in several brain disorders including the thymus disease and bipolar disorder. This microRNA has also been shown to be down regulated in several brain cancers such as neuroblastomas. The reduced expression of the microRNA-154 is a predictor of progression and prognosis of human gliomas. This data strongly support it's important role in brain tumors. Our findings are of particular interest in relation the handle exposure to the pathology of the head, the [inaudible 00:13:13] 20, 50 millisieverts. The equivalent to 1,000, 2,000 chest x-rays and can reach a lifetime cumulative exposure around two sieverts for left hippocampus and one sievert for right hippocampus. Dr Carolyn Lam:                That really makes me go, yikes. But Manos, as an interventional cardiologist yourself, what are your thoughts? And also your thoughts please on that other paper that's in this week's journal? Dr Manos Brilakis:            First of all, let me just congratulate Maria Andreassi, she's been one of the leaders in this area and published several papers and this is one of them. It's really important to have these studies because unfortunately we as interventional cardiologists tend to forget about the negative affects of radiation because as you hear, people don't really see them and this can happen many years down the line. And by the time they happen, it's too late. It's really useful to have the studies to bring our attention the importance of keeping the radiation exposure to the patient and to ourselves as low as possible.                                                 The other paper in addition to the one just discussed, is a paper that looks at DNA damage on operators performing endovascular aortic repair. As a preface, these are procedures demonstrated the aortic aneurism repairs which are very intense radiation wise. They are long procedures, fielding can sometimes be challenging for the operator. There is significant exposure of the operator to x-ray. What they did is they measured some markers of DNA damage and repair. Specifically gamma-H1AX and DDR, the DNA damage response marker and the pATM. They measured them in circulating lymphocytes in operators who performed the endovascular aortic aneurism. What they found is that there were significantly higher levels of those markers immediately after those operators performed those procedures. And they did the same thing after x-ray using leg shielding.                                                 That's a very good reminder for us that the x-ray tube actually is not on the top of the table, but the x-ray tube, the generator, of the x-rays is actually on the bottom. Then the x-ray goes through the patient and the detector is at the top of the table and what happens is the x-ray comes from below the patient and gets scattered from the patient and coming towards the operator so actually it's the legs get the higher dose during any sort of x-ray guided procedure. Sometimes we're forgetting importance of shielding the legs 'cause we think the legs, whatever the muscles, the bones, they're fine. But as the study shows, it's not just the muscles and the bones there but the whole circulation blood gets exposed to x-ray in the lower extremity circulation and that can translate to many other potentially adverse events. Dr Carolyn Lam:                Manos, I love that you manage both these papers. What important messages for increase in risk awareness. This was really very, very well accomplished by both these papers. As well by the editorial that you asked for and that was so well written by Dr. Charles Chambers on both these papers. But beyond risk awareness, what I really love is what you brought up just a while earlier about risk reduction and methods that we can take, for example, in the second paper, by Dr. Modoari and colleagues about shielding the legs. What are the implications for example, wearing a helmet or shielding the head for interventional cardiologists? What do you think? Dr Manos Brilakis:            These are very, very good points. The reality is for the head there have been a couple studied that looked at shielding with lead caps or there's some lead free caps that can be worn and also there are radiation protective glasses. However, what was interesting, there was a paper earlier last year that showed that because the radiation actually comes from below the operator that wearing those helmets, although it seems appealing, it is simple to do obviously, it actually did not significantly reduce the dose to the brain and it only partially reduced the dose to the eyes. Though shielding is useful but may not be as good as we think it is.                                                 In my mind, the starting point of all this is the basics of radiation safety which again, sound very simple and we learn about them in the beginning of training, unfortunately what happen is people tend to forget them as time goes by. These are things like don't step on the x-ray pedal unless you need to look at the pictures and that's very common done. People just have this heavy foot syndrome. They keep on x-raying when they don't need to. There's also the important things having the patient as high as possible and the detector as close to the patient so there is not as much distance for the x-ray to travel. Things like using low, not very steep angles so there is not as much radiation because they have to go through less amount of tissue. And there's some technologies actually coming along there's some technologies that focus the radiation beam only specific areas. And cut the overall dose. And there are x-ray machines that also can have much less radiation overall for the patient and the operator. As you said, having good shielding habits is very important. Dr Carolyn Lam:                Yeah, that's exactly it. That risk awareness should lead to action. I'm just curious, who do you think should primarily take hold of these risk reduction and safety procedures and the enforcement and so on? Us as a community, but what do you think of the role of things like professional societies, quality improvement programs, FDA even? Dr Manos Brilakis:            It's a great point. What we hear here Maria's comments on this as well. But my feeling is absolutely societies are very important for leading these efforts and they do have actually guidelines. There's procedural guidelines for radiation protection. But the end of the day it's the individuals themselves, the operators, each and every one who is in charge of this in their care or his own cath lab and their procedures. Dr Maria Andreassi:        I agree. We all of our findings can contribute to the increase of cross cultural assessment in cath lab and by promoting the diffusion but not the reduction technologies whereas diligent about your protection habits. Moreover it is important to let the design, the relationship between occupational radiation exposure, clinical risk and there are very important future studies studying larger population. We should focus on the molecular epidemiology studies by using biomarkers and this will be clinical and points as early predictors of a clinical event. Because this information is a model likely to better define the risk of radiation use disease at low doses as a comparative tool, the classical epidemiological approach that require a very large sample sizes spread over [inaudible 00:20:51].                                                 Now it's time where largest studies involving scientific societies at an international level. Possible breaking the additional exposure in already recruited the Roth case. And by combining the conventional epidemiology, and the molecular studies and the expected results to better define the clinical risk as a good lesson to implement a more effective protection program. And better as the surveillance at the individual level. Dr Carolyn Lam:                That is wonderful. And thank you, this truly is an international call, isn't it? Another thing that we should keep in mind that all measures that we use to protect our patient from receiving excessive radiation is likely to help us as well as cardiologists.                                                 Thank you so much, both of you, for joining me today on this podcast. What an important message and I'm sure that our listeners will agree. Thank you listeners for joining us. Tune in again next week.  

When it comes to your podcast you've established the content calendar, decided on the hosts, booked your guests, identified the target audience, and determined the topics as well as the title. Now it's time to start recording. But how do you take your podcast from conception to an iTunes subscription?  In Part II of our podcast preparation Erin Deihl and Allison Keller of Improve It are back in the studio to quiz host Michael Dennis on all of the technical aspects of launching a podcast. With nearly 60 episodes of the Chicago Marketing Podcast under his belt Michael shares all of the tips and tricks he's learned with his guests and with you. In this week's episode you'll hear all about: -how to select the correct portable recording devices -setting up your mics -which accessories make podcast recording easier -audio editing platforms & options -which website(s) to host your podcast -how to sync with iTunes -iTunes technical requirements -and much more! For more on Erin Diehl and Improve It check out their website: http://www.improveitchicago.com/

Erin Diehl is the CEO and founder of Improve It and she is no stranger to this podcast. Erin's first visit to the Chicago Marketing Podcast was a fan favorite and in the weeks following she reached out to host Michael Dennis inquiring about how to launch her own Improve It podcast and incorporate it into their promotion and outreach. Instead of having this discussion over a cup of coffee, Michael invited the Improve It squad back on the podcast to give them, as well as the listening audience, the scoop on how to utilize an original podcast to strategically grow your business and expand your brand. Erin and Improve It's Director of Operations Allison Keller join Michael in-studio to discuss: The importance of establishing a content calendar Researching your target audience Developing goals for your podcast The importance of guests and partners How to determine and establish a structure for each episode and more

In Episode 86 of The Weekly Yes, And Podcast - Travis interviews Erin Diehl, the CEO and Founder of Improve It. Erin has been a life-long performer who found improvisation and has turned it into a successful business of inspiring leaders and cultures - as well as giving philanthropiclly to the community. It is rare that Travis gets to interview other improvisors, and Erin doesn't disappoint as she shares why the principles of improvisation are so special to her, and how they are a powerful tool in the workplace.  Find out more about Erin and Improve It!    

In this episode, Chris Martin (@Chrismartin76) interviews Lee Jussim (@PsychRabble), Professor of Social Psychology at Rutgers, The State University of New Jersey. He conducts research on stereotypes and stereotype accuracy, and blogs at Rabble Rouser.   0:00 Lee’s work on the myth of stereotype inaccuracy 7:11 Blatant biases in conventional social research 10:26 What’s inside Lee’s upcoming books about politics & social psychology? 14:57 Is stereotype accuracy finally getting the coverage it needs? 23:20 People mostly discard stereotypes when they have individuating information 26:57 Stereotypes of liberals and conservatives—accuracy, inaccuracy, and real-world problems 33:00 It’s the prejudice, not the stereotyping **** You can learn more Lee Jussim at his website. Here’s a recent talk by Lee: Science Going Bad and How to Improve It. Books mentioned during the interview: Social Perception and Social Reality: Why Accuracy Dominates Bias and Self-Fulfilling Prophecy by Lee Jussim: The Politics of Social Psychology, edited by Jarret T. Crawford and Lee Jussim Handbook of Prejudice, Stereotyping, and Discrimination, 2nd edition, edited by Todd D. Nelson:   Selected Quotes "I would like to think of my field of social psychology as a scientific field. I believe in science. I am enthusiastic about it. And so I am acutely pained when the field that I so strongly identify with, and want to advance, has basic failures in conduct as a normal science. And I discovered these failures when I examined the claims about stereotype inaccuracy." * "The idea of confirmation bias is people they selectively seek out information that confirms their pre-existing beliefs, and they’re more critical of information that disconfirms their beliefs. And as far as I can tell those patterns really do pervade the social sciences. And one way that manifests is—compare stereotype accuracy or inaccuracy to almost any area! If people are going to make any claim that say intrinsic motivation increases academic achievement, they’re going to have data to support the claim. They’re either going to have their own data or cite some famous review article or meta-analysis. But if they want to claim that stereotypes are inaccurate, they don’t need any data—that’s fine! You can just do that!!!" * "If people on the extreme left are over-represented—and there is good evidence for that in academia, especially in the social sciences and humanities—and if such people are most likely to unjustifiable exaggerate the views of their ideological opponents, you’re going to have academia filled with people who despise conservatives because they truly see them as fascists and Nazis. And so why is that a problem? It’s a problem intellectually for all sorts of reasons. It feeds back into the confirmation bias problem. To the extent that the social sciences address political issues and simply stigmatize people who disagree with their views then it’s going to be very difficult to have an honest conversation about zillions of politicized issues."   Other episodes of Half Hour of Heterodoxy.

Learn the latest in lipid lowering therapy in this extensive discussion with Dr. Paul S. Jellinger, MD, MACE, Professor of Medicine at the University of Miami and Chair of the writing committee for the American Association of Clinical Endocrinologists (AACE) 2017 Guidelines for the Management of Dyslipidemia and Prevention of Cardiovascular Disease (CVD). Topics include ezetimibe, PCSK9, FOURIER trial, statin myopathy, CoQ10, fish oil, fibrates and more. For a more basic discussion of dyslipidemia check out episode #10. Full show notes are available at http://thecurbsiders.com/podcast Join our newsletter mailing list. Rate us on iTunes, recommend a guest or topic and give feedback at thecurbsiders@gmail.com. Time Stamps 00:00 Intro 03:10 Rapid fire questions 08:15 Dyslipidemia defined 10:26 Classifying dyslipidemia 13:21 Diagnosing Familial Hypercholesterolemia 17:48 A difficult lipid case discussed 22:40 Lp (a), Apo B and LDL particle concentration 28:40 What labs to order 31:31 ACC/AHA versus other risk scores 38:21 IMPROVE-IT 41:35 Non-statin medications discussed 45:05 Hypertriglyceridemia fibrates and fish oil 48:25 How often to check the lipid panel 49:58 Statin Myopathy and CoQ10 54:17 FOURIER, PCSK9 and very low LDLs 59:43 Extreme risk category discussed 62:34 Is plaque regression possible? 64:12 Take home points 67:08 Outro Tags: assistant, care, cholesterol, doctor, education family, fish oil, foam, foamed, health, hospitalist, hospital, internal, internist, ldl, lipid, medicine, medical, myopathy, nurse, pcsk9, physician, practitioner, primary, statin, resident, student

Dr. Carolyn Lam: Welcome to Circulation on the Run, your weekly podcast summary and backstage pass to the journal and its editors. I'm Dr. Carolyn Lam, associate editor from the National Heart Center and Duke National University of Singapore. Today we will be discussing the pooled analysis results of the 10 ODYSSEY Trials with important implications for the reduction of lipids in major cardiovascular events. But first, here's your summary of this week's journal. The first paper provides experimental data on vascular disease that brings into focus the critical roles of transcription factors such as GATA2 in the maintenance of endothelial cell function, as well as the role of selected microRNAs as a novel player of vascular regulation. In this study by first author Dr. Hartman, corresponding author Dr. Thum from Hanover Medical School, and colleagues, authors used GATA2 gain and loss of function experiments in human umbilical vein endothelial cells to identify a key role of GATA2 as a master regulator of multiple endothelial functions, and this via microRNA-dependent mechanisms. Global microRNA screening identified several GATA2-regulated microRNAs, including miR-126 and miR-221. GATA2 deficiency led to vascular abnormalities, whereas supplementation with miR-126 normalized vascular function. In a mouse model of carotid injury, GATA2 was reduced and systemic supplementation of miR-126-coupled nanoparticles enhanced miR-126 availability in the carotid artery and improved reendothelialization of injured carotid arteries in vivo. In summary, GATA2-mediated regulation of miR-126 and miR-221 has an important impact on endothelial biology. Thus, modulation of GATA2 and its targets miR-126 and miR-221 represents a promising therapeutic strategy for the treatment of vascular diseases. The next study is the first to show that current smokers from the general population have lower levels of circulating cardiac troponin I, a seemingly paradoxical observation given the known detrimental cardiovascular impact of cigarette smoking. First author Dr. Lyngbakken, corresponding author Dr. Omland, and colleagues from the University of Oslo used data from the large population-based HUNT study, in which cardiac troponin I was measured in 3,824 never smokers, 2,341 former smokers, and 2,550 current smokers. Current smokers had significantly lower levels of cardiac troponin I than never smokers and former smokers, an association that remains significant even after adjustment for potential confounders. The authors also found an association between increasing concentrations of troponin I and clinical endpoints, namely acute myocardial infarction, heart failure, and cardiovascular death in the total cohort. However, this association was attenuated in current smokers and was significantly weaker than in never or former smokers with a p for interaction of 0.003. The prognostic accuracy of troponin I as assessed by C-statistics was lower in current smokers than in never smokers. Troponin I provided no incremental prognostic information to the Framingham Cardiovascular Disease risk score in the current smokers. Together, these results suggest that mechanistic pathways other than those involving subclinical myocardial injury may be responsible for the cardiovascular risk associated with current smoking. Future studies are needed to determine whether a lower cardiac troponin I threshold should be considered for exclusion of myocardial infarction in smokers or whether prognostic tools other than measurement of cardiac troponins should be utilized when evaluating risk of future events in current smokers. The next study contributes to our understanding of cardiomyocyte signaling in response to ischemic injury. In the study by first author Dr. [Wool 00:05:04], corresponding author Dr. [Ju 00:05:04] from Tongji University School of Medicine in Shanghai, and colleagues, authors sought to understand the role of low-density lipoprotein receptor-related proteins 5 and 6 as well as beta-catenin signaling in the heart. They did this using conditional cardiomyocyte-specific knockout mice who had surgically induced myocardial infarction. They found that deletion of lipoprotein receptor-related proteins 5 and 6 promoted cardiac ischemic insults. Conversely, deficiency of beta-catenin, a downstream target, was beneficial in ischemic injury. Interestingly, although both insulin-like growth factor-binding protein 4 and Dickkopf-related protein 1 are secreted beta-catenin pathway inhibitors, the former protected the ischemic heart by inhibiting beta-catenin, whereas the latter enhanced the injury response mainly through inducing lipoprotein-related protein 5 and 6 endocytosis and degradation. These findings really add to our understanding of the beta-catenin signaling pathway in ischemic injury and suggests that new therapeutic strategies in ischemic heart disease may involve fine-tuning these signaling pathways. The next paper from the International Consortium of Vascular Registries is the first study allowing an assessment of variations in repair of abdominal aortic aneurysms in 11 countries over 3 continents represented by the Society of Vascular Surgery and European Society for Vascular Surgery. Dr. Beck from University of Alabama-Birmingham School of Medicine, and colleagues, looked at registry data for open and endovascular abdominal aortic aneurysm repair during 2010 to 2013, collected from 11 countries. These were Australia, Denmark, Hungary, Iceland, New Zealand, Norway, Sweden, Finland, Switzerland, Germany, and the United States. Among more than 51,000 patients, utilization of endovascular aortic repair for intact aneurysms varied from 28% in Hungary to 79% in the United States, and for ruptured aneurysms from 5% in Denmark to 52% in the United States. In addition to the between-country variations, significant variations were present between centers within each country in terms of endovascular aortic repair use and rate of small aneurysm repair. Countries that more frequently treated small aneurysms tended to use the endovascular approach more frequently. Octogenarians made up 23% of all patients, with a range of 12% in Hungary to 29% in Australia. In countries with a fee for service reimbursement systems, such as Australia, Germany, Switzerland, and the United States, the proportion of small aneurysms and octogenarians undergoing intact aneurysm repair was higher compared to countries with a population-based reimbursement model. In general, center-level variation within countries in the management of aneurysms was as important as variation between counties. Hence, this study shows that despite homogeneous guidelines from professional societies, there is significant variation in the management of abdominal aortic aneurysms, most notably for intact aneurysm diameter at repair, utilization of endovascular approaches, and the treatment of elderly patients. These findings suggest that there is an opportunity for further international harmonization of treatment algorithms for abdominal aortic aneurysms. This is discussed in an accompanying editorial entitled, Vascular Surgeons Leading the Way in Global Quality Improvement, by Dr. Fairman. The final paper from Dr. Gibson at Beth Israel Deaconess Medical Center and Harvard Medical School and colleagues, presents the results of the apoAI event reducing in ischemic syndromes I, or AEGIS-I, trial, which was a multicenter, randomized, doubleblind, placebo-controlled dose-ranging phase 2b trial of CSL112, which is an infusible, plasma-derived apoAI that has been studied in normal subjects and those with stable coronary artery disease, but now studied in the current study in patients with acute myocardial infarction. The trial showed that among patients with acute myocardial infarction, four weekly infusions of a reconstituted, infusible, human apoAI, CSL112, was associated with a dose-dependent elevation of circulating apoAI and cholesterol efflux capacity without adverse hepatic or renal outcomes. The potential benefit of CSL112 to reduce major adverse cardiovascular events will need to be assessed in an adequately powered phase 3 trial. Now for our future discussion. Today I am delighted to have with us Dr. Kausik Ray from Imperial College London, who's the first and corresponding author of a new paper regarding the pooled analysis of the 10 ODYSSEY Trials. To discuss it with us is Dr. Carol Watson, associate editor from UCLA. Kausik, just let me start by congratulating you on this paper. I believe this is the first data that allows us to look under the 50 mg/dL mark of LDL and really ask if the LDL MACE relationship extends below this level. Dr. Kausik Ray: Yes, the reason for looking at this is that the IMPROVE-IT trial really looked at people down to an average LDL cholesterol of about 54, and with the new PCSK9 inhibitors, which instead of giving you a 20% further reduction LDL, they give you the opportunity for a further 50 to 60% reduction. We actually get the chance to get people down to levels like 25 mg/dL, and the question is, does the benefit continue at that level? We did a pooled analysis of 10 of the ODYSSEY Trials, really in some ways to try and help predict what you might see in ODYSSEY outcomes, what you might see in the [Fuliay 00:12:00] trial, and to also manage expectations as well, because there's probably been a lot of hype around the two New England Journal papers about 50, 60% reductions of all potential reductions based on small numbers of events. So the question is, if you reduce LDL by 39 mg/dL, how might that reduce your risk, and is the relationship continuous? So those were the aims. Dr. Carolyn Lam: That's great, and maybe could you give us an idea of the number of patients you are looking at and the number of events? Dr. Kausik Ray: Yeah. In the 10 pool studies, we had just under 5,000 individuals, and we had just about 6,700 person years' worth of followup. In total, we had 104 first MACE events. To put this into context, it's about one third of the number of events that the first [framing 00:12:53] of analysis had. It's an observation analysis rather than randomized trial data, so you got to bear that in mind with the usual caveats that go with observational data. But the same endpoints that were adjudicated, this is [inaudible 00:13:10] heart disease death, non-fatal MI, ischemic stroke, and unstable angina requiring hospitalization. This is the same endpoint that is in the ODYSSEY Outcomes Trial, so it's interesting in that regard. Dr. Carolyn Lam: Yeah, it sure is. So what's the bottom line? What did you find? Dr. Kausik Ray: What we found was that there was a continuous relationship all the way down to LDL cholesterol levels of about 25 mg/dL, that every 39 mg/dL lower on treatment LDL, your risk went down by about 24%. If you looked at [apo-like 00:13:48] approaching be on non-HDL cholesterol, again, you found the same continuous relationship with a similar point estimate for a similar standardized difference in LDL cholesterol. We also looked at many of the guidelines, talk about percentage reduction. We actually looked at percentage reductions. If you start with a baseline LDL of X and you achieve a 50% further reduction in LDL, how much further benefit does that give you? A 50% further reduction gave you a 29% further lower risk of MACE. So we didn't find any threshold or limit all the way down to LDLs of about 25. Dr. Carolyn Lam: That's really a key, novel finding that you contributed, so congratulations once again. I suppose the question will always be, you're talking about relative risk reductions here. At such low levels, can you give us an idea of the absolute risk reductions? Dr. Kausik Ray: Yes. You've got to remember that the relative risk reductions are what you can apply to population differences. If you pick a high-risk patient population, you would expect to see a much bigger absolute risk reduction than maybe this study or another study. Similarly, if you pick a low-risk group, you are going to see a much smaller absolute benefit. I always try to advise a little bit of caution that if you basically look at the range ... If you start with let's say an LDL of 150 and you go down to let's say an LDL of 25, you are talking about a 1.25% absolute risk reduction. Remember, these patients are possibly going to be a slightly lower risk than the ones that are recruited into the ODYSSEY Outcomes and into the [Fuliay 00:15:46] trial, for example. Dr. Carolyn Lam: I think you mentioned what I was going to just ask you about. This is observational. You had 104 events, and I suppose another limitation might be that your followup was two years at max, if I'm not wrong? What do you say about that, and are there plans for future analyses? Dr. Kausik Ray: Within the context of these studies, I think that the whole of this data will eventually become dwarfed by what we see with the big CDOTs, because you've got 18, 27,000 people, 3 years' worth of exposure and followups, so you are going to have many, many more events. That is a limitation, but I think what is interesting is that we know that the baseline LDL cholesterol level is around about 90 mg/dL. We don't actually know what the actual baseline ... because the baseline [characters 00:16:43] haven't been published for ODYSSEY Outcomes, but the [Fuliays 00:16:46] around about 89. What it tells you is what the point estimate is likely to be. It's likely to be in the 24 to 32% ballpark because that's what your baseline LDL is and that's what we'd predict in the regression lines that we observed here. I think that we're not going to get many more events in these studies because largely the randomized period of followup is now over. Many of these people are now into open labels, extensions for safety, so we won't get many more events from this. In terms of, I think, the way people should maybe look at this is possibly as a taster for what's to come in the next 18 months or so. I think for the time being it answers two questions. Is lower likely to be better? And it is. I think the other question it tells is how might you get people down to LDLs below 50? One of the important things was that if you were just on statins, in this population, if you were recruited on the basis of a high baseline LDL, you got no additional people down to LDLs below 50. You got under 10% with add-on [inaudible 00:18:05], but you got around about 50% when you used the PCSK9 inhibitor as an add-on to existing therapy. It tells you about how to get to such low levels as well. I think that's the other key thing that it actually gives you. We did an analysis of safety [inaudible 00:18:23], and I think that's really important. Once you see the efficacy, or if you see the MACE events continue to go down ... If you looked at treatment-emergent adverse events ... and I completely take the fact that it's every side effect reported altogether, which may or may not be linked to LDL levels specifically, but when we did that, the relationship actually was just a horizontal line, so there was no relationship with percentage reduction or on treatment LDL, so it gave us a nice idea of both safety and efficacy that we might experience in the big outcome studies. Dr. Carolyn Lam: All right. Obviously the big outcome studies are going to be game changers, and I'd really love to invite [Carol Scotts 00:19:09] here, because there's a whole lot of other things that need to be considered if this becomes the case, isn't it? Carol, I really appreciated that you invited an editorial, and the editorial is by Neil Stone who entitles it, Looking Beyond Statins: Will the Dollars Make Cents? Please tell us about the discussions about this paper that occurred. Dr. Carol Lam: I would again like to congratulate Dr. Ray on a fantastic paper, and I would like to reiterate exactly what he said. I think it really does give us some comfort about this class of medication and its relative safety. I think that's very important, because I can't tell you how many patients I get and how many referring physicians I get who worry when their patients come back with LDLs of 20 or below. I think that gave us some comfort, and I do also think it was very important to show that this would fall along the same regression line that statins perhaps would fall. As with all the caveats that Dr. Ray said, I agree with all of them, but I do say this is a tasty little taster, and I appreciate and congratulate you for publishing this. The editorial by Dr. Neil Stone was quite interesting. As you said, he subtitled it, Will the Dollars Make Cents? C E N T S or S E N S E, sort of a play on words there. Will the relative benefits that we can achieve with this class of medications make sense for the cost of these drugs? That's obviously a very separate issue from what was discussed in the manuscript, but it's something to think about. We understand that there are additional patients that will be helped if they can get their LDL down, and we hope that that will translate into the outcomes. Again, just as Dr. Ray mentioned, we will have to wait for the cardiovascular outcomes trials to be completed. When they are, if they do show the benefits that we hope, will their price point make them accessible to enough patients for this to be a widely applied, utilized therapy? Or will they not? That's part of what was discussed in Dr. Stone's editorial. Dr. Kausik Ray: When we were writing the manuscript and stuff like that, and we were doing this and everybody's like, "Oh, wow, look at the graphs." I said, "Look, we need to balance all of these bits and reassure ... We've got an opportunity." So I suggested them giving those additional analyses, and you saw how big the online supplement was. There was a ton of work that we put into this, and to format it into a concise ... I really want to just thank the editorial board for giving us the chance and actually being able to help us and work with us on this, because it's really important. I hope people look at all of those things because it will help people also that question the LDL. They all talk about the hypothesis and the safety of really low LDLs, and people come off statins as a result. I think this will help. Dr. Carolyn Lam: You're listening to Circulation on the Run. Thank you so much for being with us, and don't forget to tune in next week.

Overview: In this episode Terrance O’Hanlon and I talk about reliability, safety and operational excellence. We dive deep into leadership and talk about how if leaders really want to be excellent at their jobs they need to get better at asking questions and listening. Terrance gives some excellent advice for leaders and for helping their workers to understand the value in their work. Terrance’s Bio: Terrence O'Hanlon, CMRP is the Publisher of Reliabilityweb.com®, RELIABILITY® Magazine and Uptime® Magazine. He is certified in Asset Management by the Institute of Asset Management and is a Certified Maintenance & Reliability Professional by SMRP. Terrence is the acting Executive Director of the Association of Asset Management Professionals (AMP). He is the executive editor and Publisher of the 5th Edition of the Asset Management Handbook. Terrence is also a voting member of the US TAG (PC251) for ISO 55000 - ASTM E53 Asset Management Standards Committee. More recently Mr. O’Hanlon has been selected as the sole US Representation through ANSI for ISO Working Group 39 to create a standard for competence in assessing and certifying Asset Management programs known as ISO 17021-5. Mr. O’Hanlon is also a member of the Institute of Asset Management, American Society of Mechanical Engineers, The Association of Facilities Engineers, Society of Maintenance and Reliability Professionals and the Society of Tribologists and Lubrication Engineers. Show Notes: There are a number of proven tools for improving reliability, yet they fail about 70% of the time. Effective leadership behind these tools is one of the key drivers behind what makes these tools successful. Reliability is directly tied to safety. Reliability goes beyond the business case. It can be a factor in promoting social good, and it and can be seen as a way of life. It can be very empowering when leaders ask workers about their jobs and about what they do and know. Not only can leaders learn more, but when workers have the opportunity to explain their work it can improve morale. Asking questions, working through inquiry and listening to answers can create a more powerful force in creating greater reliability. Leaders need to work through master to discovery. Leaders need to build trust with their subordinates and have to in turn trust them. Organizations should work to preempt failures and work to prevent failures from “piercing the shell” of organizations. Organizations should work to avoid letting defects into the system. They should work to find and remove the sources of the potential defects before they enter the system, which creates greater reliability, as opposed to allowing defects into the system and then finding and fixing them later. Detection is a necessary skill, but the leverage is not letting the defects into the system. You can help do that through empowering and engaging the team and empowering team members to fix the defects before they enter the system without having to go through a bureaucratic process. Sign up for our Newsletter: www.v-speedsafety.com/email-subscription Resources: Books: How to Measure Anything by Douglas Hubbard, The Toyota Way by Jeffery Liker, Don't Just Fix It, Improve It! by Winston Ledet and Sherri Abshire 99 Percent Invisible Podcast About Air France Flight 447: http://99percentinvisible.org/episode/children-of-the-magenta-automation-paradox-pt-1/ Contact: Web: www.reliabilityweb.com LinkedIn: https://www.linkedin.com/in/reliabilityweb Keywords: Disruptive leadership podcast, safety podcast, leadership podcast, safety innovation podcast, reliability, reliability leadership, high-reliability organizations podcast, HRO podcast, tower safety, wireless safety

In this episode, we talked to Erin Diehl, founder of Improve It, (www.improveitchicago.com) a corporate team-building workshop company that helps organizations use improvisation to build better, "yes, and" cultures.

Amol and Reena want you to understand the following: 1. When added to moderate dose statin, the IMPROVE-IT randomized trial showed that ezetimibe improved clinical outcomes in patients after acute coronary syndrome. 2. A network meta-analysis showed that no blood pressure lowering therapy improved mortality in patients with diabetes and chronic kidney disease. The combination of ACE-inhibitors and ...The post Summer Replay 4: Ezetimibe and clinical outcomes, BP lowering in diabetes and kidney disease appeared first on Healthy Debate.

Amol and Reena want you to understand the following: 1. When added to moderate dose statin, the IMPROVE-IT randomized trial showed that ezetimibe improved clinical outcomes in patients after acute coronary syndrome. 2. A network meta-analysis showed that no blood pressure lowering therapy improved mortality in patients with diabetes and chronic kidney disease. The combination of ACE-inhibitors and ... The post Summer Replay 4: Ezetimibe and clinical outcomes, BP lowering in diabetes and kidney disease appeared first on Healthy Debate.

Amol and Reena want you to understand the following: 1. When added to moderate dose statin, the IMPROVE-IT randomized trial showed that ezetimibe improved clinical outcomes in patients after acute coronary syndrome. 2. A network meta-analysis showed that no blood pressure lowering therapy improved mortality in patients with diabetes and chronic kidney disease. The combination of ACE-inhibitors and ...The post Debatable Landmarks: Ezetimibe and clinical outcomes, BP lowering in diabetes and kidney disease appeared first on Healthy Debate.

Amol and Reena want you to understand the following: 1. When added to moderate dose statin, the IMPROVE-IT randomized trial showed that ezetimibe improved clinical outcomes in patients after acute coronary syndrome. 2. A network meta-analysis showed that no blood pressure lowering therapy improved mortality in patients with diabetes and chronic kidney disease. The combination of ACE-inhibitors and ... The post Debatable Landmarks: Ezetimibe and clinical outcomes, BP lowering in diabetes and kidney disease appeared first on Healthy Debate.

Alistair Lindsey talks to Christopher Cannon, Havard Clinical Research Institute, about the results of his IMPROVE-IT trial, which examined clinical outcomes of adding ezetimibe to simvastatin. This podcast was recorded at the American Heart Association scientific sessions in Chicago.

Pharmacy Business Profit Assessment ASSESS IT, MEASURE IT, IMPROVE IT. Increase your profitability and efficiency. Get the support your pharmacy business needs to stay competitive and profitable. Let our experience work for you to bring more $$ to your bottom line. Your completed, ‘confidential’ pharmacy profile will be reviewed by our operations staff

Pharmacy Business Profit Assessment ASSESS IT, MEASURE IT, IMPROVE IT. Increase your profitability and efficiency. Get the support your pharmacy business needs to stay competitive and profitable. Let our experience work for you to bring more $$ to your bottom line. Your completed, ‘confidential' pharmacy profile will be reviewed by our operations staff and opportunities will be identified in key areas such as: Labor, Inventory, Pricing, Technology and Promotional Programs that will positively impact YOUR BOTTOM LINE. YOUR SUCCESS is the basis of our ‘RESULTS DRIVEN' programs. Take our confidential survey now to see how we can save you money. Start Your Assessment HERE> $  About S&L Solutions:  S&L Solutions LLC is a comprehensive Pharmacy Services Organization that provides Community Pharmacy Support Programs, Pharmacist Sourcing (Staffing and Permanent Placement) as well as proven Marketing Solutions utilizing our “Pathways to Good Health and Nutrition," TM Program. S&L Solutions specializes in providing customized business solutions for privately owned pharmacies. With a nationwide presence and a wide network of resources and contacts throughout the U.S. and abroad, S&L has the assets to fulfill an independnet pharmacy's needs. S&L Solutions Phone: (888) 273-0325 See omnystudio.com/listener for privacy information.

Straight Thinking #28: Memory: Five Ways to Improve It