Podcasts about tumors

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BUFFALO, NY – August 19, 2025 – A new #research paper was #published in Volume 16 of Oncotarget on August 19, 2025, titled “The SCD1 inhibitor aramchol interacts with regorafenib to kill GI tumor cells in vitro and in vivo.” In this study, led by first authors Laurence Booth and Michael R. Booth, along with corresponding author Paul Dent from Virginia Commonwealth University, researchers investigated how aramchol, a drug originally developed for liver disease, works with the cancer drug regorafenib in gastrointestinal (GI) tumor cells. They found that the combination is effective, especially in tumor cells with a specific genetic variant. The combined approach offers a potential new strategy for treating liver and colon cancers. Gastrointestinal cancers, such as liver and colon cancer, are serious global health challenges. Regorafenib, already approved for cancer treatment, can have limited impact and frequently causes side effects. Aramchol, a drug developed to treat fatty liver disease, affects how cancer cells process fats and energy. In this study, researchers tested whether combining these two drugs could improve GI cancer treatment, both in cells and mouse models. The results showed that the drug combination killed liver and colorectal cancer cells more effectively than either drug alone. In animal models, mice with human liver tumors had slower tumor growth, without showing signs of weight loss or other toxicity. The researchers also found that aramchol and regorafenib work together to block important survival pathways inside cancer cells. This combination was especially effective in cells with a genetic variant called ATG16L1 T300, which is more common in people of African ancestry. The treatment triggered stress responses in the cancer cells and disrupted key proteins required for survival. It also activated autophagy, a natural recycling process that clears out damaged parts, eventually leading to cancer cell death. “Aramchol interacted with the multi-kinase inhibitors sorafenib, regorafenib or lenvatinib, to kill GI tumor cells, with regorafenib exhibiting the greatest effect.” Aramchol is currently in clinical trials for fatty liver disease and has a well-established safety profile, while regorafenib is already FDA-approved for cancer treatment. Together, their combination could advance fast into clinical testing for patients with GI cancers. However, researchers note that additional studies are needed to support the launch of early-phase clinical trials. Altogether, this study may offer a more effective and less toxic alternative to current treatments for GI cancers. It also highlights the role of genetic variants in shaping treatment response, suggesting that future therapies could be more precisely tailored to each patient's unique genetic profile. DOI - https://doi.org/10.18632/oncotarget.28762 Correspondence to - Paul Dent - paul.dent@vcuhealth.org Video short - https://www.youtube.com/watch?v=5saAqsqxi-Q Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28762 Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ Keywords - cancer, macroautophagy, flux; ER stress, aramchol, regorafenib To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM

Is divine healing meant to be rare—or a normal part of everyday life? Evangelist and author Chad Gonzales joins Jen Lilley and Billy Hallowell for a powerful conversation on why healing is God's will for everyone, how to live free from sickness, and why most Christians are missing out on the supernatural life Jesus promised.From jaw-dropping miracle stories—blind eyes opening, tumors vanishing, legs growing out—to breaking down common misconceptions about Paul's thorn and the gifts of the Spirit, Chad challenges believers to rethink what's possible when they truly understand their identity in Christ.Topics covered: • Why healing should be a lifestyle, not a rare event • How to shift your focus from sickness to the Healer • The dangers of “panic prayer” • Real-life testimonies that will blow your mind • What the Bible really says about living free from sicknessThis episode will ignite your faith, and stir up a hunger for the supernatural.

In today's Beating Cancer Daily episode, Saranne explores creating a living legacy with excitement and optimism. As someone who has beaten Stage IV cancer for 30 years, Saranne shares her perspective on why it's essential to consciously think about and enjoy crafting a legacy, regardless of the timeline we have. Join her as she discusses fun and creative ways to leave a lasting imprint, from recording books for loved ones to planting living markers of our time. Get ready to be inspired and discover how embracing the concept of legacy can bring joy and depth to our lives as we beat cancer daily together.2025 People's Choice Podcast Awards Finalist Ranked the Top 5 Best Cancer Podcasts by CancerCare News in 2024 & 2025, and #1 Rated Cancer Survivor Podcast by FeedSpot in 2024 Beating Cancer Daily is listened to in over 130 countries across 7 continents and features over 390 original daily episodes hosted by Stage IV survivor  Saranne Rothberg.   To learn more about Host Saranne Rothberg and The ComedyCures Foundation:https://www.comedycures.org/ To write to Saranne or a guest:https://www.comedycures.org/contact-8 To record a message to Saranne or a guest:https://www.speakpipe.com/BCD_Comments_Suggestions To sign up for the free Health Builder Series live on Zoom with Saranne and Jacqui, go to The ComedyCures Foundation's homepage:https://www.comedycures.org/ Please support the creation of more original episodes of Beating Cancer Daily and other free ComedyCures Foundation programs with a tax-deductible contribution:http://bit.ly/ComedyCuresDonate THANK YOU! Please tell a friend whom we may help, and please support us with a beautiful review. Have a blessed day! Saranne 

BUFFALO, NY – August 15, 2025 – A new #research paper was #published in Volume 16 of Oncotarget on August 13, 2025, titled “Clinical and analytical validation of MI Cancer Seek®, a companion diagnostic whole exome and whole transcriptome sequencing-based comprehensive molecular profiling assay.” In this study, first authors Valeriy Domenyuk and Kasey Benson, along with corresponding author David Spetzler from Caris Life Sciences in Irving, Texas, introduce MI Cancer Seek, an FDA-approved test designed to deliver comprehensive tumor profiling. MI Cancer Seek demonstrated strong concordance with other FDA-approved companion diagnostics and serves as a powerful tool to guide treatment decisions in both adult and pediatric cancer patients. Cancer remains one of the most complex and diverse diseases to treat. With many targeted therapies currently FDA-approved, selecting the right one for a specific patient requires detailed genetic insights. MI Cancer Seek addresses this need by analyzing both DNA and RNA from a single tumor sample. The tool identifies key biomarkers linked to FDA-approved treatments for several major cancers, including breast, lung, colon, melanoma, and endometrial cancers. One of the most significant strengths of MI Cancer Seek is its ability to deliver accurate and reliable results from minimal tissue input (50 ng). Even when analyzing formalin-fixed paraffin-embedded samples, which are widely used but often degraded, the test maintained high levels of accuracy. It successfully detected important genetic alterations such as PIK3CA, EGFR, BRAF, and KRAS/NRAS mutations and measured tumor mutational burden (TMB) and microsatellite instability (MSI), both of which are key indicators for immunotherapy response. In clinical comparisons, the test achieved over 97% agreement with other FDA-approved diagnostic tools, confirming its reliability in detecting critical biomarkers. Notably, it showed near-perfect accuracy in identifying MSI status in colorectal and endometrial cancers. The researchers also demonstrated that the test maintains precision across different lab conditions and varying DNA input levels, confirming its robustness for routine clinical use. Beyond its role as a companion diagnostic, MI Cancer Seek incorporates additional features developed under its predecessor, MI Tumor Seek Hybrid. These include detection of homologous recombination deficiency, structural variants, and cancer-related viruses. It also includes advanced tools such as the Genomic Probability Score for identifying the tissue of origin in cancers of unknown primary, as well as a gene signature to guide first-line chemotherapy in colorectal cancer. “One limitation to be considered is the low PPA for ERBB2 CNA detection.” By offering deeper genetic insights from a single, small sample, MI Cancer Seek has the potential to streamline diagnostics, reduce testing costs, and connect patients to effective therapies more quickly. As precision medicine continues to expand, this assay stands out as a comprehensive and efficient solution for meeting the evolving needs of modern oncology. DOI - https://doi.org/10.18632/oncotarget.28761 Correspondence to - David Spetzler - dspetzler@carisls.com Video short - https://www.youtube.com/watch?v=D4hd2FxCYY8 Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM

Thanks for watching the Harland Highway. Tickets to see Harland Williams live stand-up comedy are available now at harlandwilliams.com! -Chubbies and Wayfair sponsor this episode!- Your new wardrobe awaits! Get $10 off @chubbies with the code [HARLANDHIGHWAY] at https://www.chubbiesshorts.com/[HARLANDHIGHWAY] #chubbiespod- -Get organized, refreshed, and back to routine for way less. Head to Wayfair.com right now to shop all things home. Wayfair. Every style. Every home. More Harland Williams: Harland Highway Podcast Video: https://www.youtube.com/c/HarlandHighwayPodcast Harland Highway Podcast Audio: https://podcasts.apple.com/us/podcast/the-harland-highway/id321980603 Instagram: https://www.instagram.com/harlandwilliams Harbling Shirts: https://www.harbling.com Official Website: https://www.harlandwilliams.com Twitter :https://twitter.com/harlandhighway?lang=en More Dr.Drew: Website: https://drdrew.com/ Instagram: https://www.instagram.com/drdrewpinsky/?hl=en #podcast #harlandwilliams Learn more about your ad choices. Visit megaphone.fm/adchoices

Can you manipulate blood flow in the tumor microenvironment to optimize drug delivery? In this episode of the BackTable Podcast, interventional oncologist Dr. Zachary Berman (UC San Diego) joins host Dr. Christopher Beck to discuss real-world applications of pressure-enabled drug delivery in local, regional liver-directed therapies like TACE and Y90.---This podcast is supported by:TriSalus Life Scienceshttp://trinavinfusion.com/---SYNPOSISThe conversation begins with an overview of the tumor microvascular environment, focusing on the abnormal nature of the new vessels that feed tumors. They then discuss the genesis of pressure-enabled drug delivery and the theory behind its efficacy. Dr. Berman explains the TriNav catheter's micro-valve design, its anti-reflux properties, and how these features enhance tumor drug delivery. He walks through his own procedure technique, comparing and contrasting it to standard embolization, and details the utility of pressure-enabled drug delivery in lobar radioembolization and larger tumors. They also explore the benefits of both balloon occlusion and microvalve catheters.Real-world cases—including neuroendocrine tumors, segmental HCC, and more—illustrate the thought process around when to use specialized technologies. The episode wraps up with a discussion of the future implications for this technology in other pathologies, cost considerations, and the potential for enhancing drug delivery with innovative approaches.---TIMESTAMPS00:00 - Introduction01:39 - The Tumor Microenvironment06:59 - Pressure-Enabled Drug Delivery Explained09:37 - Technical Aspects of Pressure-Enabled Catheters21:48 - Case 1: Grade 3 Neuroendocrine Tumor34:06 - Case 2: Hepatocellular Carcinoma with Tumor and Vein36:01 - Case 3: TACE for Segmental HCC in Decompensated Cirrhosis38:58 - Case 4: Large Heterogenous Cholangiocarcinoma40:40 - Case 5: Lobar Neuroendocrine Tumor42:38 - Case 6: Segmental HCC with Central Necrosis47:52 - Best Practices and Technical Considerations57:52 - Future Directions in Pressure-Directed Embolotherapy59:48 - Conclusion and Final Thoughts---RESOURCESJVIR 2024 Jaroch et al.:https://pubmed.ncbi.nlm.nih.gov/38969336/

The role of neuronal influences on cancer pathogenesis and progression is increasingly appreciated in the nervous system. Neurons have been shown to enhance the proliferation and migration of gliomas, a glial-derived tumor of the CNS, via diffusible paracrine factors or synaptic inputs onto tumor cells. In glioblastomas, a highly aggressive glioma, mostly glutamatergic inputs have been identified. While the potential for glioblastomas to receive projections from neurons of other neurotransmitter subtypes, such as from cholinergic neurons, has recently been discovered in xenotransplantation models, whether synapses can form between human cholinergic neurons and glioblastoma cells and consequences of these inputs and other non-synaptic mechanisms are still unknown.   Human induced pluripotent stem cell-based models have been emerging as a powerful platform for studying human-specific disease mechanisms. Today's guests developed a co-culture model for the study of neuron-tumor interactions by combining patient derived glioblastoma organoids and hiPSC-derived cholinergic neurons. They will discuss their recent findings and what it means for understanding and potentially treating a tumor for which there is no known cure. GuestsGuo-li Ming, MD, PhD, Department of Neuroscience and Mahoney Institute for Neurosciences, Perelman School of Medicine, University of PennsylvaniaHongjun Song, PhD, Department of Neuroscience and Mahoney Institute for Neurosciences, Perelman School of Medicine, University of Pennsylvania Yusha Sun, Neuroscience Graduate Group, Perelman School of Medicine, University of PennsylvaniaHostJanet Rossant, Editor-in-Chief, Stem Cell Reports and The Gairdner FoundationSupporting ContentPaper link:  Cholinergic neuron-to-glioblastoma synapses in a human iPSC-derived co-culture model, Stem Cell ReportsAbout Stem Cell ReportsStem Cell Reports is the open access, peer-reviewed journal of the International Society for Stem Cell Research (ISSCR) for communicating basic discoveries in stem cell research, in addition to translational and clinical studies. Stem Cell Reports focuses on original research with conceptual or practical advances that are of broad interest to stem cell biologists and clinicians.X: @StemCellReportsAbout ISSCRWith nearly 5,000 members from more than 80 countries, the International Society for Stem Cell Research (@ISSCR) is the preeminent global, cross-disciplinary, science-based organization dedicated to stem cell research and its translation to the clinic. The ISSCR mission is to promote excellence in stem cell science and applications to human health.ISSCR StaffKeith Alm, Chief Executive OfficerYvonne Fisher, Managing Editor, Stem Cell ReportsKym Kilbourne, Director of Media and Strategic CommunicationsMegan Koch, Senior Marketing ManagerJack Mosher, Scientific DirectorHunter Reed, Senior Marketing Coordinator

Congressman Andy Barr gives President Donald Trump credit for Apple's decision to expand in Kentucky, the state is joining forces with the Better Business Bureau and the AARP to create a website giving Kentuckians tips to avoid scams, and University of Louisville researchers create world's largest brain tumor database.

Schau dir das Video zu dieser Folge an: Keto bei KREBS: Mythos oder Wahrheit? | Die ECHTE Wissenschaft der ketogenen Ernährung gegen KrebsYouTube Kanal gleich abonnieren und keine neue Folge mehr verpassenZusammenfassungIn dieser Episode räumt Julia Tulipan mit den Mythen rund um die ketogene Ernährung bei Krebs auf. Anstatt polarisierender Social-Media-Debatten liefert sie eine wissenschaftlich fundierte Analyse der Studienlage. Du erfährst, dass es nicht darum geht, den Tumor "auszuhungern", sondern um die komplexen Wirkmechanismen von Ketonen: Sie senken Blutzucker und Insulin, reduzieren Entzündungen, modulieren das Immunsystem und können gesunde Zellen schützen, während sie Tumorzellen für Therapien verwundbarer machen. Julia klärt die Fakten zum Warburg-Effekt (nicht widerlegt!) und zur metabolischen Flexibilität von Krebszellen. Sie entkräftet die Behauptung, Ketone würden Tumore füttern, und zeigt stattdessen die antitumorale Wirkung, die in vielen Studien beobachtet wird. Wir beleuchten vielversprechende klinische Studien zu Bauchspeicheldrüsen- und Brustkrebs, die zeigen, wie Keto in Kombination mit Standardtherapien die Krankheitsstabilität und Lebensqualität verbessern kann. Julias Fazit: Keto ist kein Allheilmittel, aber eine wissenschaftlich gut begründete, ergänzende Strategie, die die Wirksamkeit konventioneller Therapien unterstützen und Nebenwirkungen reduzieren kann. Eine professionelle Begleitung ist dabei unerlässlich.Was du in dieser Episode lernst

In today's episode, Saranne delves into the world of tumor humor as she reflects on her experience with hair loss during her cancer journey. As a survivor, Saranne understands the emotional impact of losing hair during cancer treatment and shares how she approached this challenging experience with a comic perspective. Join her as she discusses the humorous side of coping with hair loss and invites listeners to participate in creating their tumor humor. Prepare for a lighthearted and insightful discussion on finding laughter in the face of adversity as we beat cancer daily together.Ranked the Top 5 Best Cancer Podcasts by CancerCare News in 2024 & 2025, and #1 Rated Cancer Survivor Podcast by FeedSpot in 2024 Beating Cancer Daily is listened to in over 130 countries across 7 continents and features over 365 original daily episodes hosted by Stage IV survivor  Saranne Rothberg.   To learn more about Host Saranne Rothberg and The ComedyCures Foundation:https://www.comedycures.org/ To write to Saranne or a guest:https://www.comedycures.org/contact-8 To record a message to Saranne or a guest:https://www.speakpipe.com/BCD_Comments_Suggestions To sign up for the free Health Builder Series live on Zoom with Saranne and Jacqui, go to The ComedyCures Foundation's homepage:https://www.comedycures.org/ Please support the creation of more original episodes of Beating Cancer Daily and other free ComedyCures Foundation programs with a tax-deductible contribution:http://bit.ly/ComedyCuresDonate THANK YOU! Please tell a friend whom we may help, and please support us with a beautiful review. Have a blessed day! Saranne 

„Wir alle hatten schon einmal HPV – nur die wenigsten wissen es.“ Prof. Dr. Mandy Mangler zählt zu den renommiertesten Gynäkologinnen Deutschlands und ist eine der wichtigsten Stimmen für Frauengesundheit. In dieser Folge BUNTE VIP GLOSS spricht sie mit Podcast-Host Jennifer Knäble über eine der am meisten unterschätzten Virusinfektionen weltweit: Humane Papillomviren – kurz HPV. Die Infektion ist extrem weit verbreitet, bleibt in den meisten Fällen unbemerkt und wird vom Immunsystem erfolgreich bekämpft. Doch bestimmte Hochrisiko-HPV-Typen können schwerwiegende gesundheitliche Folgen haben – sie führen zu Zellveränderungen, aus denen sich über Jahre hinweg Krebs entwickeln kann. — In Deutschland sterben jedes Jahr mehrere tausend Menschen an HPV-bedingten Krebsarten – darunter Gebärmutterhalskrebs, Mund-Rachen-Krebs oder Analkrebs. Trotzdem wird das Virus noch immer häufig als „Frauenthema“ abgetan – ein gefährlicher Irrtum, denn auch Männer können sich infizieren und sind Teil der Infektionskette. „Fast 3.000 Männer erkranken hierzulande jährlich an einem bösartigen Tumor, zum Beispiel an Peniskrebs, der durch HPV verursacht wurde“, so die Expertin. — Die gute Nachricht: Wir können uns schützen. Prof. Dr. Mangler erklärt, wie die HPV-Impfung wirkt, für wen sie sinnvoll ist und warum nicht nur junge Mädchen, sondern ebenso Jungen, Männer und Erwachsene davon profitieren können. Sie beschreibt die Übertragungswege des Virus, erklärt die begrenzte Schutzwirkung von Kondomen und zeigt, warum regelmäßige Vorsorgeuntersuchungen und fundierte Aufklärung so wichtig sind im Kampf gegen HPV-bedingte Krebserkrankungen. Prof. Dr. Mandy Mangler bei BUNTE VIP GLOSS. — Über unsere Expertin: Prof. Dr. Mandy Mangler (Jahrgang 1977) ist Chefärztin an zwei Berliner Kliniken für Gynäkologie und Geburtshilfe, spezialisiert auf operative Verfahren und gynäkologische Onkologie. Sie unterrichtet im Studiengang „Hebammenwissenschaft“ an der Evangelischen Hochschule Berlin und engagiert sich als Vorsitzende der Gesellschaft für Gynäkologie und Geburtsmedizin Berlin sowie der Berliner Chefärztinnen und Chefärzte (BLFG e. V.). Bekannt ist sie zudem als Host des Podcasts „Gyncast“. Für ihren Einsatz für Gleichstellung und Diversität in der Medizin wurde sie 2022 mit dem Berliner Frauenpreis ausgezeichnet. Mandy Mangler ist Mutter von fünf Kindern und lebt mit ihrem Partner in Berlin. — Hier findet ihr alle Informationen zu unseren Podcast-Partnern: https://www.wonderlink.de/@buntevipgloss-partner — Ein BUNTE Original Podcast.

Born with NF1-PN, a rare genetic disorder, Austin Fields spent his childhood learning how to live in a body riddled with benign tumors. Though removal surgery is the main treatment for this painful condition, a new medication has recently been approved for adults with NF1-PN. Our experts explain what it's like to live with this condition and how this novel drug is enhancing patients' quality of life. Learn More: https://radiohealthjournal.org/the-new-drug-that-shrinks-tumors-for-patients-with-nf1-pn Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode, we review the high-yield topic ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Paraneoplastic Effects of Tumors⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠from the Oncology section at ⁠⁠⁠⁠Medbullets.com⁠⁠⁠⁠⁠⁠Follow⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Medbullets⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbulletsLinkedin: https://www.linkedin.com/company/medbullets

What is in the This Week in Science Podcast? This Week:  Atomic Slits, Vaccines Work, Wifi Fingerprint, Ancient Teeth, Deep Life, Fat for Tumors, Immunity in your head, Cultural Function, Brain Generics, and Much More Science you can trust! Become a Patron! Check out the full unedited episode of our podcast on YouTube or Twitch. […] The post 30 July, 2025 – Episode 1024 – This is the Science You Can Trust appeared first on This Week in Science - The Kickass Science Podcast.

Welcome to the Oncology Brothers podcast! In this episode, hosts Drs. Rahul and Rohit Gosain, practicing community oncologists, share their key takeaways from a session on NTRK Fusion Positive Solid Malignancies, they moderated during a satellite event at ASCO 2025 in partnership with Medscape Global Oncology. Join us as we discuss: •⁠  ⁠The prevalence of NTRK fusions in various cancers and why community oncologists should be aware of them. •⁠  ⁠The importance of comprehensive next-generation sequencing (NGS) for detecting these fusions across diverse histologies. •⁠  ⁠Available treatment options, including first-generation NTRK inhibitors like larotrectinib and entrectinib, and their efficacy in improving overall and progression-free survival. •⁠  ⁠Insights into the CNS activity of these treatments and the common side effects patients may experience. •⁠  ⁠Special considerations for pediatric patients, including formulation challenges and the potential for re-challenging with NTRK inhibitors. Don't forget to check out the full accredited enduring program by Medscape Global Oncology linked below, and earn your CME credit.  https://www.medscape.org/viewarticle/1002679?src=acdmpart_onc-brothers_1002679  Follow us on social media: •⁠  ⁠X/Twitter: https://twitter.com/oncbrothers •⁠  ⁠Instagram: https://www.instagram.com/oncbrothers •⁠  Website: https://oncbrothers.com/ #entrectinib #larotrectinib #repotrectinib

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Host: Darryl S. Chutka, M.D. Guest: Eric J. Moore, M.D. Salivary gland tumors can be benign or malignant, as well as primary or metastatic. Malignant salivary gland tumors usually present after the 6th decade, whereas benign lesions tend to occur a bit earlier, usually in the 4th to 5th decades. An interesting statistic is that the vast majority of salivary gland tumors occur in the parotid, only about 10% occur in the submandibular salivary gland and less than 4% in the minor salivary glands. Fortunately, most parotid tumors are benign. Previous radiation as well as occupational exposure to silica and nitrosamines have been linked to malignant parotid tumors. What should a primary care clinician do when we discover a mass in the parotid gland? What imaging studies are helpful? What treatment is available and what happens if the tumor recurs? These are all questions I'll be asking my guest, Eric J. Moore, M.D., Chair of Otolaryngology and Head and Neck Surgery at the Mayo Clinic as we discuss “Parotid Gland Tumors”. Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts 

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In this episode of 'Don't Cut Your Own Bangs,' host Danielle Ireland introduces John Kippen, a resilience and empowerment coach, magician, and motivational speaker. John shares his incredible journey of overcoming a life-threatening brain tumor and how it transformed his life and career.  Throughout the episode, John discusses his healing journey, the power of vulnerability, and the importance of facing one's limiting beliefs. He also reveals the origins of his unique phrase 'impossible really means I am possible' and offers a special gift to listeners. Tune in to uncover valuable wisdom nuggets and be inspired by John's story of triumph over adversity.   00:00 Introduction to the Episode 00:40 Meet John Kippen: A Multihyphenate Talent 01:23 John's Life-Altering Diagnosis 05:46 The Surgery and Its Aftermath 08:04 The Road to Recovery 13:30 Embracing the New Normal 17:29 The Power of Truth and Magic 29:14 The Power of Magic and Connection 29:31 Introducing Treasured: A Journal for Self-Discovery 30:44 The Magic of Personal Connection 32:59 Overcoming Personal Struggles Through Magic 34:38 The Journey to Self-Acceptance 35:42 The Importance of Asking and Vulnerability 50:24 The TED Talk Experience 54:34 Final Thoughts and Encouragement   RATE, REVIEW, SUBSCRIBE TO “DON'T CUT YOUR OWN BANGS”  Like your favorite recipe or song, the best things in life are shared. When you rate, review, and subscribe to this podcast, your engagement helps me connect  with other listeners just like you. Plus, subscriptions just make life easier for everybody. It's one less thing for you to think about and you can easily keep up to date on everything that's new. So, please rate, review, and subscribe today.    DANIELLE IRELAND, LCSW I greatly appreciate your support and engagement as part of the Don't Cut Your Own Bangs community. Feel free to reach out with questions, comments, or anything you'd like to share. You can connect with me at any of the links below.   JOHN KIPPEN: https://www.ted.com/talks/john_kippen_being_different_is_my_super_power_magic_saved_my_life   https://www.johnkippen.com   DANIELLE IRELAND, LCSW Website: https://danielleireland.com/ The Treasured Journal: https://danielleireland.com/journal Instagram: https://www.instagram.com/danielleireland_lcsw TikTok: https://www.tiktok.com/@dontcutyourownbangspod?_t=ZP-8yFHmVNPKtq&_r=1 Transcript:   John Kippen Edited Interview [00:00:00] [00:00:07] Hello. Hello, this is Danielle Ireland and you are catching an episode of Don't Cut Your Own Bangs. And today I have the great pleasure of introducing you to someone I can now call a new friend John Kippen. John is a multihyphenate. He has had quite a life and he's an excellent storyteller. So this episode you're gonna wanna buckle up. [00:00:31] It is so good. Get those AirPods in, go on your walk, get safely in your car, get ready to listen because this is just an absolutely beautiful episode. But let me tell you a little bit about John. John is a resilience and empowerment coach. He was and is the CEO of a very successful IT company. [00:00:49] He was a main stage performer at the Magic Castle in Los Angeles, so if that just gives you a little insight, is the level of his magic. He is a motivational speaker. He's a life coach, and. He has a TED talk that has received over a million views. And the heartbeat of this TED talk is how he triumphs over tragedy with a diagnosis of a tumor the size of a golf ball that is separating his brainstem and the procedure he needed to save his life, changed his life forever. [00:01:23] Doing the work of healing does not come easily to anyone, but as John so beautifully puts in this episode, if John can do it, you can do it. He's using his stories, his vulnerable and raw experiences, and talking about not only what happened to him, but how he moved through the impossible. [00:01:45] He actually coins a phrase that I love and I'm going to keep. Which is that impossible really means I am possible. So the ultimate magic trick, the ultimate illusion is what your limiting beliefs are about yourself, and how do you use facing those fears and those limiting beliefs to transform your life. [00:02:08] And in John's case, he takes that healing and offers it as a gift to us. As listeners to his clients and his coaching practice to the readers of his book, he has authored a book The Forward by None other than the Jamie Lee Curtis from all of the places. You know her most recently. The Bear where she won an Emmy, but everything everywhere, all at once. [00:02:32] She and John are buds, and she believes in him and believes in his work, and as a champion of that work, it just adds a little extra sparkle and fairy dust to the beautiful work that he's already doing to say that he's been vetted by someone who is so sparkly and magnetic and also deeply entrenched in holding space for the truth and honoring the truth. [00:02:52] This is a heartfelt episode, so what I would recommend. If you're in a place to do so is you might wanna jot some notes down because John drops some beautiful wisdom nuggets in this episode. And the book that he authored is playing The Hand You're Dealt. And what I wanna share too, we talk about it in the episode, but I wanna highlight this 'cause it's really important. [00:03:12] John is giving everyone who listens to the episode a free gift, but it is not linked in the show notes. It is only available to those of you who listen. It's a special little surprise embedded in the episode that you have to listen to find, but it is a free gift from him to you. So without further ado, get ready to sit back, relax, and enjoy the beautiful wisdom of John Kippen. [00:03:35] ​ [00:03:36] Kippen, multihyphenate resilience and empowerment, coach magician, keynote speaker, author, and all around. Nice guy. Thank you for joining me today on the Don't Cut Your Own Bangs podcast. [00:03:47] Danielle: Hollywood legend wrote the forward of his beautiful book, playing the Hand You're Dealt Forward by the one and Only Take It Away, John, Jamie [00:03:58] John: Lee Curtis. [00:03:59] Danielle: Jamie Lee Curtis. Yes. So you have to stay and listen to the entire episode because he's going to tease out a special little giveaway that will only be revealed in the audio. [00:04:10] So you gotta listen. It's not gonna be linked in the show notes, folks. So buckle up, sit down. This is gonna be a great episode with a fun gift for you, a special little dose of magic hidden inside. So, John, you, I mean, all the different fun things that we listed about what you do. You're a magician, you're a motivational speaker, you're a coach. [00:04:30] What I know doing the work I do as a therapist is the skills and trade that you're building your life on. Those were skills that they were. Hard one, like nobody chooses, in my opinion and in my experience, no one chooses to go into a helping profession that hasn't needed help in their life. It's like the, our healing becomes our medicine. [00:04:54] And I really wanna learn about not just what you offer, but your healing journey that put you in the unique position you're in to do the work you do. So, welcome and I'd love to hear from you. [00:05:05] John: So just quickly, the Reader's Digest version of my backstory. Grew up Los Angeles, middle class family, two great parents loving, no sisters or brothers, had everything I needed. [00:05:18] They sent me to a nice school and, I got into theater, started doing theater, in college. I studied theater and became the big man on campus because pretty much I grabbed every opportunity that presented itself. Started a computer company out of college. 'cause I'm a creative problem solver. [00:05:38] That's the thread that goes through everything I do in my life. [00:05:42] Mm-hmm. [00:05:42] John: I look at a problem, I say, how am I gonna solve that? [00:05:45] Mm-hmm. [00:05:46] John: And then in June of July of 2002, I was diagnosed with a four half centimeter brain tumor called an acoustic neuroma. [00:05:55] Danielle: Yes. And this was, so it was slowly severing your brainstem? Correct. [00:05:59] John: It was displacing the brainstem. Causing not only hearing issues, but dizziness upon standing or walking. [00:06:07] Mm-hmm. [00:06:08] John: I had to have something done with it. I would not have survived. [00:06:12] Mm-hmm. [00:06:14] John: And. It was a whirlwind , I went and saw the doctor who finally diagnosed it after seeing him the MRI films, and he, he had no bedside manner. [00:06:25] I remember sitting on the examining room table, right. And the, the tissue paper is crinkling under my butt. Mm-hmm. I could feel the, I could sense the temperature. I'm heightened sensitivity. [00:06:37] And he looks up at the MRI after talking to a neurosurgeon, and he turns around and says, John, you have a four and a half centimeter brain tumor. [00:06:46] It's killing you. We're operating you on Friday. You're gonna go deaf in your left ear, and there's a possibility for some facial weakness. We're gonna do everything we can to prevent that. And he left [00:07:01] Danielle: the room. So he knew, and in his own. Brash in abrupt way, essentially prepared you for the outcome and challenges that would come assuming the surgery was a success? [00:07:17] John: Yeah. He is a world renowned acoustic neuroma surgeon. He's one of the guys you go to, when you have this kind of tumor and that's all he does. Wow. But he literally left the room and I'm sitting there and I didn't bring anybody in and [00:07:31] yeah. [00:07:32] John: A tip to anyone who's potentially going in for a serious diagnosis. [00:07:36] Yeah. [00:07:37] John: Bring a friend or a family member. [00:07:39] Because it goes in one ear and out the other, you're in shock. Right. Right. When you get home and you say, wait a minute, he said that surgery gonna be four hours or 14 hours or 20. How, how long ago and you have all these questions. Yeah. And you know, getting ahold of the doctor to ask them again is just not the way our medical system works. [00:08:01] He's back to back, to back to back patients. [00:08:04] So, I checked in the night before, they did blood tests and I tried to get an hour or two sleep, 6:00 AM my clockwork the orderly came in and said, okay, get naked, get on this cold gurney. What a sheet over you and we're going take you to the operating room. [00:08:21] Danielle: I wanna pause your story for a moment. 'cause there's a couple things that I, I wanna tease out a little. So one is you, the way that you tell your story, so well probably because you've told it on stages, you've shared it with others, you've written about it. There is something about a trauma. [00:08:37] That really marks the sort of BCAD of life. And the way you shared, I felt like I was in the room with you when you were getting this bomb of news dropped on you so you were theater trained, theater kid, a creative person, a creative problem solver, and a business owner. [00:08:57] Like I, I think about that often when people are experiencing trauma. What, what was life sort of the, the illusion of normalcy. The, the, you know, the predictability of this is my life and this is my to-do list and this is my calendar. So before that moment, you were just a guy on the west coast running a business. [00:09:17] Is that right? [00:09:18] John: Very successful business. [00:09:19] Danielle: And I, I just wanna share briefly too, I haven't met too many other only children. Theater background 'cause that's me too. [00:09:30] John: Oh, really? [00:09:31] Danielle: I'm an only child and I was a theater major and started acting when I was 13, so before. But, the creative problem solver, God, my theater background has paid dividends in ways I didn't know at the time. [00:09:42] I didn't know that when I was preparing for this interview, but now that you've said that, it's like that thing that I couldn't put my finger on has clicked into place. [00:09:49] John: I love doing improv. [00:09:51] Improv is the, you know, everybody talks about being in the moment. [00:09:57] Yeah. [00:09:57] John: What does that really mean, being in the moment? [00:10:00] When you do improv, you have to be in the moment. Otherwise you fall flat. And everybody, you're doing improv looks at you going. Well, it's your turn. [00:10:10] Danielle: You've tapped in. Now you've gotta say something. How are you gonna move the story forward? [00:10:14] Exactly. I feel most alive when I'm engaged in moments like that. And I, it's, I'm not a, a adrenaline junkie, but I would say that's my high, it's the, rush of connecting with somebody like that. So you were running a very successful business. This bomb has dropped. [00:10:32] You can barely remember what you were told and what your life is likely going to be. Assuming everything goes well, what is going to happen when you wake up off your op? And how long was your operation? [00:10:46] John: 15 hours. [00:10:48] Danielle: And the surgery was a success. They were able to remove the golf ice tumor. [00:10:52] Yeah. So they removed the fall sized tumor. [00:10:54] John: I didn't have time to think, you know, I got one of my guys who worked for me told him that he was gonna be running the company for a month or two. He agreed. [00:11:05] Mm-hmm. [00:11:05] John: Had to shovel up some more money to get him to do it, but, you know, it is what it is. You do what you have to do. [00:11:11] Yeah. And then,, I just tried to think positively, hope for the best. Plan for the worst. You know, I had someone gonna stay with me the first week, make food because I just wanted to recover and I didn't know what it was gonna be like. [00:11:27] Danielle: Yeah. You're like, I just need a week to recover, and then I'm just gonna hop back into life, hopefully. [00:11:31] John: Rolling the gurney into the surgical, prep area. [00:11:35] The nurse saying, Hey John, you know, we know we have to shape after your head. You want me to do it now or after you're under. [00:11:42] Danielle: So you didn't even know that they were gonna shave your head. Well, I didn't think about it. [00:11:48] John: I mean, if I had thought about it, I got a shaved part of my head. [00:11:51] Danielle: Right. [00:11:52] John: I said to her, please. [00:11:56] Danielle: Yeah. [00:11:58] John: And so, they roll me into the operating room. You got these really bright lights, , blinding you, and you're laying there and they're like, okay, you're gonna count back toward five. [00:12:09] The next thing I know, I hear faint voices and it was like I was 30 meters deep in a pool. Struggling to get to the surface. And I remember this like it was yesterday, literally trying to swim to the service to regain consciousness. [00:12:26] And finally when I got enough, I realized that my dad was sitting on the edge of my bed holding my hand, [00:12:34] and [00:12:34] John: he was smiling at me, but I didn't see my mom. [00:12:40] So I asked my dad for my glasses and he handed me the glasses. And I remember trying to put the, and then I realized my head's bandage. [00:12:48] Danielle: Oh, right. [00:12:50] John: So I had to figure out how to get the glasses in Cockeye to get 'em on my face, right? [00:12:55] And the look on her face was one of horror. What did these butchers do to my son's face? And at that point, I didn't know my face was paralyzed. Because I have full feeling, I just can't move it. [00:13:10] Danielle: So you currently, you still have full feeling in your face. You just lost mobility, [00:13:14] John: so I didn't really understand what that look was. [00:13:18] Danielle: Right. How could you? [00:13:19] John: And then my mom handed me her compact makeup. [00:13:22] And I opened it up and I'm like, holy crap. And then, I'm still getting [00:13:30] accustomed to, the one thing I noticed is leading into surgery, I was constantly dizzy and that dizziness was gone. [00:13:38] Danielle: Wow. [00:13:39] John: And that was like, oh my God, what a relief. [00:13:42] Mm-hmm. [00:13:43] John: So the doctor finally made his way in and I was like, so when's my face gonna move? And he said, John, we were, successful. [00:13:50] The tumors removed. Right when we were close the incision, your face stopped moving. But we think it's just to do the swelling, and once the swelling goes down, your face should start moving again. So I'm like, okay. I can handle that. That's a, it's not a permanent thing. I can deal with it. [00:14:05] So I'm in the hospital a week and, they're like, when you can do three laps around the hospital floor, without a walker, we'll send you home. [00:14:16] So that became my goal. I remember getting outta bed and then they said, no, no, no. Wait for the, I said, no. The doctor said that I need to rock three laps around. [00:14:26] I want to get the hell out of here [00:14:28] Five days I got home. My dad drove me home and I sat on my couch and now I'm like, okay, I can start healing and check email here and there. And I was taking lots of naps. And then I coughed and I touched the back of my neck and it was wet. [00:14:45] Mm. [00:14:47] John: Oh, it was a spinal fluid leak on the base of the incision. [00:14:51] Whew. [00:14:53] John: So immediately I called the doctor's office and the said, oh, get your ass back here. And I went back to the hospital three times with them to redo the bandaging to try to prevent the leak. [00:15:05] Danielle: Wait, you call the hospital. Hey, their spinal fluid leaking out of my surgical incision. And they're like, yeah, you should get in a car and drive yourself to the hospital. [00:15:16] John: They didn't say how I should get to the hospital. [00:15:19] Danielle: Okay. Fair, fair. But that, [00:15:22] okay. Wow. ' [00:15:24] John: cause that's not good. [00:15:25] And there was potential for getting, spinal meningitis in that. From what I understand is one of the most extreme pains out there. [00:15:35] Okay. [00:15:35] John: I went back and forth three different times over that week. [00:15:39] They tried to, it was just as right behind my ear, right at the base of the incision. So, there was no way that they were going to be able to, put a pressure manage to keep that and so it could start healing. [00:15:51] Danielle: Mm-hmm. [00:15:52] John: So they finally said, all right, tomorrow you're gonna come in and we're gonna, redo the incision and pull more belly fat outta your belly to fill the hole. [00:16:01] And Yeah. This time they used staples, man, thick Frankenstein. [00:16:07] All the way up. [00:16:08] But then I'm like, I was only in the hospital for a day. And then, and I'm like, okay, I can relax. I remember getting up and brushing my teeth, you know, and I'm looking at the mirror and God, , I don't recognize that guy. [00:16:24] Yeah. And I got rid of all the mirrors in my house. [00:16:30] I didn't want a constant reminder. [00:16:33] My face was screwed up. [00:16:34] Danielle: I, there's so much specificity to what is uniquely your story. [00:16:46] Mm-hmm. [00:16:47] Danielle: But what I have found is when people. Are able to share elements of their experience. It's when you go into the specificity of what you experienced. I can see myself in so many elements of your story in my own, like when we get in deeper, it becomes somehow more accessible and universal. [00:17:16] And in that way, you're not alone, even though it happened to you and that detail about your removing the mirrors from your home. It, it brings me to something I really wanted to ask you about. You share by saying, and then also , by, actually demonstrating in your TED talk that, once you began the healing process of really addressing your depression after your operation, that, the story, it led you to magic, literally. And I also think in a more magical way, beyond performing an illusion. And I know not to call it a trick, I learned that from arrested development. [00:18:03] But, there's something you said that I wanted to quote that it's amazing how accepting kids are of the truth. You open up your TED talk, which I will link in the show notes so people can see. But that you mentioned that this in a way that your permission and your humor and your honesty, it created levity and lightness. [00:18:27] For something that would be considered maybe so precious and heavy. And what I wanna speak to, and open up a question if that's okay, is, I'm curious what your relationship with the truth is because I think humor in its highest expression is allowing us to laugh at something that we see the truth in. [00:18:49] And yet it's this razor's edge between laughing at someone or laughing at something versus inviting us to laugh at the, the human experience that we maybe don't know how to name or express in another way. But I wanna know personally for you, what your relationship is with the truth and the value of embracing it. [00:19:13] And then in your line of work as a coach, where do you see people struggle with it? [00:19:19] John: Truth is an illusion. [00:19:21] Danielle: Ooh, tell me more. That just, that was a zingy response that you popped right out. Please tell me more. [00:19:28] John: Yeah. Truth. Everybody has their own truth. [00:19:31] Danielle: Oh, well there you go. [00:19:32] John: Their own perspective, [00:19:34] Danielle: uhhuh, [00:19:35] John: And the truth is formed out of your limiting beliefs. [00:19:41] Danielle: So the truth is formed out of your limited beliefs, [00:19:44] John: your limiting beliefs. [00:19:45] Danielle: Limiting beliefs. Okay. [00:19:47] John: Yeah. [00:19:48] I just wanted to take a slight step back. [00:19:50] Danielle: Mm-hmm. [00:19:51] John: I told you this was gonna be the Reader's Digest version. [00:19:54] Danielle: Yes. [00:19:54] John: But it took me 12 years [00:19:57] To come out of that hiding. Wow. 12 years. [00:20:02] Danielle: How old were you when you had your operation? [00:20:05] John: 33. [00:20:06] Danielle: 33. Okay. [00:20:08] John: And fortunately for me, I could work from home. But I miss so many celebrations with friends and family. 'cause I just didn't want to have to explain it. I didn't want to have to deal with the looks, , and I tell this story on my TED Talk and in my book. You know, at a restaurant I wanted to get a burger at Tony Aroma's. And I'm sitting there by myself and in a booth, and there's a booth right in front of me and there's a family with a kid, two parents and a kid. And the kid's squirming and gets up and turns around and is now on his knees on the bench and looking at me. [00:20:44] And he gets up and he comes over and he says, Mr, what's wrong with your face? And in that moment, I didn't want to have a five or 6-year-old come over and Right. And I'm like, okay, I had the strength to come out and go to a restaurant. I have to deal with this. So I started talking to this little boy [00:21:06] Danielle: Mm. [00:21:07] John: And saying, I had a medical procedure that caused me not to with my face before I could continue his mom grabbing him [00:21:16] mm-hmm. [00:21:17] John: The arm and drug him back and said, don't bother him. The nice man, he has enough troubles already. And I couldn't leave it there. [00:21:25] Mm-hmm. [00:21:27] John: So I had to go to the little boy and I knelt down and I got eye level and I said, I love my new face because it's different. [00:21:34] It's different just like yours. And I remember it like it was yesterday, he took his fingers and he tried to distort his face to be crooked like mine. And he turned to his mom and said, look, mom, I could do that too. And then he went back to eating his meal. His question was answered. [00:21:56] He had no judgment. And his parents were like, holy crap, did we just learn a lesson? How to raise our child? [00:22:03] They whispered, thank you on their way out. [00:22:07] Danielle: But there is something I, there, there's something to that woman's response to you that really resonated with me. [00:22:14] And it also, highlights the point you made so well about the, essentially the truth being relative. Because she projected onto you what her perception of your life was. Don't bother the nice man one, she didn't know you were nice, though. You are. But she didn't know that. Right. And she also didn't know what your troubles were or weren't, and she assumed that. [00:22:39] John: But I always wonder what her motives were. [00:22:41] Danielle: Right. [00:22:42] John: was it to make me comfortable or was it to make her and her son comfortable [00:22:48] Danielle: it for her? I think so. [00:22:50] John: And that's how I took it. [00:22:51] Danielle: I remember. So I have two children and I was pregnant once before and lost that pregnancy. [00:22:57] 12 weeks in. And I haven't thought about this in a very long time, but I remember going into, a annual doctor's appointment and she saw on the chart that I was listed as pregnant and clearly now was not. And it was in her own discomfort of not, she was asking me about the baby thinking, 'cause she was not my ob, GYN it was a different type of doctor. [00:23:20] And, she caught. Oh, and then I had sort of explained to her what that meant, and then she said, well, I'm sure, you blame yourself and I want you to know it's not your fault. Like she took her discomfort and tried to turn it into, she positioned herself above as someone who knew what he was experiencing and wanted to offer me this sympathy that was, one, she was wrong. [00:23:45] I totally misplaced. Yeah. I didn't blame myself. And it, that, that moment was such an extension of her own inability to hold the moment and the discomfort of the moment, and, tried to offer it up as a gift for me, which that's, yeah. [00:24:03] John: It's your perception of how you deal with that. [00:24:06] Danielle: Mm-hmm. [00:24:07] John: Losing a child can be. Empowering because you know that you can try again and get a child that is not gonna have any kind of defects and is gonna have a good life. And you know whether or not you believe in God or not. [00:24:24] Danielle: Yeah. [00:24:25] John: Things happen for a reason and we don't always understand the reason for them. [00:24:30] Danielle: I don't know if it, what the reason was, but I can say a gift from that was that somebody who lived with a very active monkey mind and a lot of head trash and some anxiety in the experience of the early grief, not for very long, but there was a moment in time where my mind was quiet, not numb, but quiet. [00:24:55] And it helped me realize, oh, there's the observer within me. Then there are the different conversations that are happening in my head that aren't me, which are maybe the perceptions that I call truth sometimes I wanna bring that same question of truth, which you had an answer I was not expecting, which I love when I never see it coming, so thank you. [00:25:18] Where do you see your clients? Because you're a coach, right? You are taking your healing and offering it as medicine to people that are trying to make a connection in their own life. So where do you see people that you work with? Struggle with the truth? [00:25:36] John: Everybody's hiding from someone something in their life. [00:25:40] They have buried something so deep and it keeps them from moving forward in their lives. 'cause it erodes their self-confidence. [00:25:50] That's what I learned through my love for performing magic. [00:25:58] Going to the magic castle, sitting at a table with a paralyzed face. [00:26:03] Yeah. I'm this overweight guy with balding, balding with a paralyzed face. And I could sit at a table and have people come to me. I tell this story sometimes, that the Magic Castle is a place where you have to get dressed up to the nines, you know? And women love to get dressed up [00:26:22] Danielle: That's true. [00:26:23] John: They're wearing their best outfits, right? And all of a sudden I'd have five or six women sitting at the table, and their reactions are very guarded. [00:26:34] Hmm. [00:26:36] John: You know, they're sitting there with their legs and arms crossed. [00:26:39] Hmm [00:26:40] John: they're leaning back. They have a smile that's just more of a grin. [00:26:45] Mm-hmm. ' [00:26:47] John: cause I don't know what I'm about. Sure. They don't know if I'm gonna be inappropriate, if I'm gonna come onto them, if I'm what it is. So they have no expectations other than they're gonna see some magic. [00:26:58] Mm-hmm. [00:26:59] John: So I start my act saying, hi guys. My name is John and I'm doing magic all my life. [00:27:05] But in 2 0 2 I had a brain tumor. And when they cut over my head, they traumatized medication, nerve offense, a paralyzed face. But something happened to me on that talk table that day, Danielle. [00:27:16] Mm-hmm. [00:27:17] John: I'm not sure what it was because I was unconscious. All I know is I recovered. I realized I had acquired some new skills and I pause. [00:27:29] Yeah. And I wait for everybody to get on the edge of their seat. Like, what happened, John, what? Skills. Skills I could acquire. I'm having brain surgery. [00:27:40] Mm-hmm. I [00:27:41] John: looked to my right and I looked to my left like it's the biggest secret. [00:27:45] Lean in and I whisper in a loud voice as I am able to visualize people's thoughts. And then I do some mental magic mentalism. Love it. And what I just did was I turned my biggest challenge into a superpower. [00:28:07] Danielle: Yes, you did. And I wanna pause you because when you said that in your talk, have, have you read Elizabeth Gilbert's book, big Magic? [00:28:15] Yes. [00:28:15] Danielle: When she talks about trickster energy, I was like, John Kippen is a freaking trickster. [00:28:22] That is trickster energy that you can shift. Before someone's very eyes. It's like you are performing magic and you are performing magic. You shifted before them and you invited them, your audience to see beyond their own limiting beliefs, their own projected truth. [00:28:47] John: They were distracted. They wanted to know why it was paralyzed, but they couldn't ask, did he have a stroke? Did he have be palsy? What was the reason? So I found them being distracted when I was performing. So I got that outta way in the first two minutes. [00:29:00] Mm-hmm. [00:29:01] John: I explained why my face is paralyzed. [00:29:03] And now I treat it as the experience is now I'm able to do superhuman things. [00:29:10] And now they're like, okay, cool. So as I perform [00:29:16] I focus on the spectator. Magic happens in your mind as a spectator. [00:29:22] Danielle: Oh, I love that magic happens in your mind [00:29:26] ​ [00:29:31] If you've ever wanted to start a journaling practice but didn't know where to start, or if you've been journaling off and on your whole life, but you're like, I wanna take this work deeper, I've got you covered. I've written a journal called Treasured, a Journal for unearthing you. It's broken down into seven key areas of your life, filled with stories, sentence stems, prompts, questions, and exercises. [00:29:51] All rooted in the work that I do with actual clients in my therapy sessions. I have given these examples to clients in sessions as homework, and they come back with insights that allow us to do such incredible work. This is something you can do in the privacy of your own home, whether you're in therapy or not. [00:30:10] It has context, it has guides. And hopefully some safety bumpers to help digging a little deeper feel possible, accessible and safe. You don't have to do this alone. And there's also a guided treasured meditation series that accompanies each section in the journal to help ease you into the processing state. [00:30:29] So my hope is to help guide you into feeling more secure with the most important relationship in your life, the one between you and you. Hop on over to the show notes and grab your copy today. And now back to the episode.​ [00:30:44] John: Magic is what you see in your mind or someone else sees in their mind. [00:30:49] Magic is that thing that immediately makes you present. [00:30:56] Danielle: Yeah. [00:30:57] John: And your, all of your sensors are now in a heightened state , whether it's a sunset or a beautiful beach or a beautiful woman or a magic trick or whatever it is, there's that sense of awe and wonder. [00:31:15] So as I would start to take each spectator, I would learn their names. [00:31:19] And I would use their names throughout the show. [00:31:22] Danielle: People love that. [00:31:23] John: People, I ask them, the one word in everybody's language that they love to hear the most is their own name . and so I use that as a way of engaging the audience. [00:31:33] They start leaning in and now they've got real smiles on their face [00:31:37] and I can literally see this wall that women in today's society are forced to put up as a self-protection mechanism. [00:31:45] Yeah. [00:31:46] John: I see this wall start to grow as they start to identify with me and they're like, I'm okay being myself. [00:31:54] And then the end of this [00:31:56] they're asking permission to hug me. [00:31:58] And , having a creative mind, I wanted to understand. What that is. What that, what was going on. [00:32:06] Danielle: You also, not only through performing magic, inviting the curiosity you could see in other people's faces into your opening act essentially, or your sleight of hand. [00:32:17] I'm gonna show you this over here so that you can not see what's coming here. Vulnerability in its purest form is magic because it's the one thing sharing the story you feel like you couldn't share. Letting somebody see the one part of you that you would never let anybody see 'cause you were so utterly convinced you would be outed or you would be cast out by exposing that vulnerability is the birthplace of true connection. [00:32:47] Yeah. Which is the ultimate magic trick. It's, it's like what they say in nightmares, if you stop and face the thing that's chasing you, it, it can't chase you anymore in the dream. And so you spent a decade, did I remember that correctly, you wanted to be a main stage performer at the Magic Castle? [00:33:06] It took you about 10 years and you did it. [00:33:08] John: I did. [00:33:09] Yeah. [00:33:09] Danielle: 10 years. [00:33:11] John: Yeah. [00:33:12] Danielle: 10 years. [00:33:13] John: It was my creative coping mechanism. I had hit rock bottom, was I suicidal? No, not really. But I was unhappy. [00:33:25] Danielle: Yeah. [00:33:26] John: I was, my girlfriend left me, and, fortunately I had a job that I could focus on. But I needed something more. And through sharing something so personal and tying magic into it and making it a positive instead of a negative [00:33:45] people are attracted to it. [00:33:49] Danielle: Yeah. Well, because you're holding fire in your hand. Yeah. You're not just saying it's possible, but you're living. You're turning it into a performance, which I think for an artist is one of the most selfless, beautiful acts. [00:34:11] John: It's what separates great artists from mediocre artists. What is he giving me to care about? [00:34:18] Danielle: I never thought about that with magic. What are they giving me to care about? [00:34:22] John: Yeah. What do I want them to think when they leave the theater? [00:34:27] Ability to put your own life in perspective. If John can, so can I. [00:34:33] That's my true message. [00:34:36] Any different is your superpower. [00:34:38] Now, my facial paralysis does not have to define me if I don't let it. [00:34:44] You know, Danielle I live my life that it's better to ask for forgiveness than permission. [00:34:51] And that's bit me in the butt numerous times. [00:34:54] Danielle: I can also say the opposite, can bite you in the butt. I think I waited probably too long, many times for permission that wasn't really coming because no one can ultimately grant it. Right? Like, if there's a path you wanna carve, like the job that you built, all of the different things that you've done, there's no resume posted on LinkedIn. [00:35:15] No one's hot. Like that's an empowerment coach slash magician slash keynote speaker, slash documentarian like that. You have to get curious and still, and listen to that little voice inside and follow that curiosity to a path that may not make sense for anyone for a really long time. And I didn't do that. [00:35:40] And that can bite you in the butt too. 'cause regret's hard to hold. [00:35:42] John: Alex SBE came out on national television [00:35:45] to his fans, to the world and said, I'm scared. I am fighting the battle of my life and I'm gonna ask for everyone's good thoughts and prayers . of what I'm going through. I reached out to Nikki Trebek, Alex's daughter and I said, Nikki, I need to perform for your dad . we're having a 75th birthday party and we don't have any entertainment. [00:36:13] So if you wanna be the entertainment, and I was like. Damn. Yes. [00:36:18] Danielle: Well, yeah. I will go to his house and perform magic for him. a [00:36:22] John: restaurant, but [00:36:23] Danielle: Oh, a restaurant. Okay. [00:36:23] John: Wrote a unique magic show [00:36:25] With Jeopardy themes and the whole nine yards and he was actually at the table as one of my assistants. [00:36:33] Oh. Along with his daughter. so he was this, he needed to understand how things worked. [00:36:39] Was a genius. And so he was constantly looking at me like, wait a minute. That's not possible. Just embrace it, Alex. You're not gonna figure it out. Just enjoy it. [00:36:52] Danielle: That's awesome. [00:36:54] John: And there's, on my website, john kipp.com. There are some magic videos and there are two videos of me performing for Alex , sat with him, and I said, Alex, I need to share something with you that, when you came out so publicly about your diagnosis [00:37:10] I asked for everybody's support and love and prayers that resonated with me. I am here to give to you. You've been a part of my life and the lives of millions of people. [00:37:27] And your life's work is meaningful. [00:37:30] I just wanted to tell you that, 'cause I had a feeling that no one ever takes the time to say thank you for your life's work. [00:37:37] And he immediately started welling up. [00:37:39] Danielle: Well, anybody who makes something look easy that we do take for granted. [00:37:45] And I think that, like I appreciate so much in the telling of your story, you share not just the struggles, but the time you had a vision of yourself. On the main stage performing at the Magic Castle, like the most elusive place where magic is. And you didn't just wanna get in, you didn't just wanna get an audition, you didn't wanna just like get to per perform an illusion, like main stage. [00:38:23] You didn't just have a goal. You had the goal and you did it, but you also say that it took you 10 years. And there's usually themes that run with anxiety, about not enoughness and the crunchiness of time. There's never enough time. I'm not enough and there's not enough time. And not being worthy. [00:38:42] Yes, yes, yes. One of my main motivations when I started this podcast originally several years ago, was I was. Starting to increasingly feel, trapped in this sort of, world of before and after story. And it was no longer feeling inspirational. It was just another measuring stick for how not enough. [00:39:03] Yeah. 'Cause it, it's great to see where somebody was and where they are, but when I'm knee deep in my own struggle when I'm the caterpillar goo and the chrysalis, and I'm not the shiny butterfly, but I'm also not the caterpillar anymore. What do I do when my life is literally a shitty pile of goo this is something that most clients don't come right out and ask me like in sessions one, two, and three. But it inevitably comes well, I've been doing this for, so many months. How much longer is it gonna take? How long is it gonna take? And I just always, I appreciate when people can acknowledge. [00:39:41] The time and consistency that goes into healing [00:39:47] John: joy is in the journey. [00:39:48] Danielle: Mm. [00:39:49] John: Not in the destination. [00:39:51] And that's the thing I really focus with my clients. [00:39:55] I have clients come to me because they're holding themselves back in their life. [00:39:59] And it's my job to get that out of them by asking open-ended questions, by building a rapport, I can trust this guy. [00:40:08] Danielle: Yeah. Would you say that's your superpower as a coach? [00:40:11] John: Through my journey of reverse engineering who I am and who I wanted to become. Coming out the other side immediately understood that it's not about me. [00:40:24] Danielle: Yes. It's only true every single time. [00:40:27] John: The joy comes from helping others get that realization, [00:40:32] That they understand they are truly powerful and have a chance to shape their destiny. [00:40:40] That's why I talk about limiting beliefs. [00:40:43] And we grow up with our parents or whoever raised us, those are our belief systems. [00:40:49] And so that's what forms who you are. You stop dreaming. [00:40:54] That's what midlife crisis is all about. [00:40:58] Danielle: Yeah. [00:40:59] John: We got educated, we got a job, we built a career. We have a family. [00:41:06] Danielle: It's, I think the version of that I hear in my sessions is essentially I did everything right. Shouldn't I be feeling better than I am? Yeah. Like, I followed all the rules. I'm winning. Why does it not feel like I'm winning? Yeah. And finding our way back to that. [00:41:29] The unlearning and the unraveling. That is a, it's a process. [00:41:34] John: I'll talk to a friend. How you doing? And so many people respond automatically living the dream. But is it your dream? You're living? [00:41:46] Whose dream are you living? Because you're wasting your life by living someone else's dream. And that's why you get to that point in life where it's not enough. [00:41:58] Cause it's not your dream. You just finished the last 30 years building. [00:42:03] Danielle: Yeah. And the joy really is in the process and there's no way to enjoy the process of fulfilling the wishes of somebody else because you, what you're constantly chasing is when I get there, then the relief will come and then you're there and you're like, well, where's my pot of gold? [00:42:22] John: Yeah. I had, I spent 20 years learning how not to hide my face. [00:42:28] And what happened in March in 2020? The pandemic hit [00:42:33] now covering your face with a mask, became not only politically correct. [00:42:41] But government mandated and I'm like sitting there thinking to myself, what do I do? So I found a company who prints things on masks and I sent them a picture of my face and a picture of the lower part of my job. [00:43:01] Danielle: Trickster energy, John Kippen trickster. That's the new hyphen to your list of all of your accomplishments. [00:43:08] John: I would walk around and strangers would look at it and not understand. [00:43:12] Danielle: Right, right. But people who knew me [00:43:15] John: would do a double take. [00:43:17] Danielle: I will not hide. [00:43:19] John: Refuses to hide. [00:43:20] Even through a global pandemic. [00:43:23] Yeah. [00:43:23] John: I'm gonna live my life [00:43:25] Danielle: mm-hmm. On [00:43:26] John: my own terms. [00:43:28] Danielle: Yeah. I work too hard, too long to get free and I will not hide for you. Wow. Wow. And [00:43:37] John: when I share that story, people like, wow, John's done some soul searching. [00:43:44] Danielle: Which is why your clients come to you. [00:43:46] John: Yeah. [00:43:46] Danielle: Yeah. I unfortunately have come across many. People in the helping profession that haven't started with their first client, which is themselves. I put myself in that camp. I've talked about it on the podcast before, but I didn't start seeing a therapist until I became one, which is probably not the right order, but I didn't realize until I was sitting there trying to help people. [00:44:09] And then my own stuff was getting activated in the session. It's called Counter Transference. And, yeah, I was like, oh shit, I gotta look at the mirror. I gotta do a little more digging. But I think a, what leads a lot of people into helping professions is its desire to heal. And it sounds like in your case you did the herculean task of lifting your own self up before you said, now what can I offer you? [00:44:39] I wanna ask, just a purely curious, selfish question before we get to the very end I wanna ask. In your book playing the Hand you're Dealt how did you connect with Jamie Lee Curtis? The same way you did Alex Trebek? Did you just find someone and you DMed them and [00:44:55] John: you're like, her assistant worked for a production company [00:45:00] in a previous job. [00:45:02] Danielle: Gotcha. [00:45:02] John: That I knew. [00:45:03] When Jamie was like, I need it. So help with my computer. Her assistant said, I've got the guy for you. And I remember being at Jamie's house. [00:45:15] She knew me before my facial surgery, and after. [00:45:18] Danielle: So you have a history then? [00:45:19] John: Oh yeah. We met in 2000. [00:45:21] Danielle: Oh, okay. [00:45:22] John: So she saw me before. [00:45:24] She saw the struggle. Sure, she has two. Great kids. [00:45:29] And she adopted me as her third child. Wow. She saw the ability to help me. And so I had a filmmaker friend of mine reach out and said, John, I'd love your story. [00:45:45] I want to film a documentary on you. And I'm like, cool. So I realized I'm paying for the damn documentary. [00:45:51] Danielle: Oh. So I wanna offer you this gift, and by the way, here's the bill. [00:45:55] John: Yes, exactly. But at that point, I'm all in and I'm like, what do I have to lose? I'm a risk taker. I can afford it. [00:46:01] I've got money in the bank. [00:46:03] Let's make sure we stay on budget or close to budget, so there I am working on Jamie's computer and I'm staring at the screen and I'm summoning the courage. Ask Jamie. So I'm telling her the story. My friend Ryan's gonna direct this documentary about my life and my journey, and then I pause and I'm just staring at the screen. [00:46:23] I feel these eyes burning into the side of my head. [00:46:26] Mm-hmm. [00:46:28] John: And Jamie says, and [00:46:32] Danielle: I love that she didn't do it for you, but she made you do it. [00:46:36] John: And then at that point, I realized what the question was. I said, Jamie, will you be in my documentary? [00:46:44] And she goes, fuck yes, I will. [00:46:48] Danielle: Yeah. [00:46:49] John: She gets it. [00:46:50] Yeah. [00:46:51] John: Going through her sobriety, she wears her sobriety on her. Shoulder as a badge of honor. [00:47:00] And that is her message. [00:47:02] Yeah. [00:47:03] John: If she can get people to stop drinking by showing up for people. That's her ultimate goal in life. And so, she saw in me what I didn't see, [00:47:18] Danielle: and you asked the question. I think it's a lesson that I feel like I'm eternally playing a game of peekaboo with where I forget, and then I remember and then I forget and then I remember. But like the opportunities that you're asking for, you have to ask. [00:47:39] Yes. You have to say the thing. Right. Which is so brave and so vulnerable. But then the magic is sometimes when you ask, someone will say Yes. Now, in your case, she was essentially lovingly poking you until you, [00:47:55] John: asked. There was a point where I was debating plastic surgery. [00:48:00] Did I want to try to fix my face? Because at the end of the day, I wanted symmetry at rest. I wanted to be able to get rid of the droopiness and just, have a symmetrical base. That's all I really wanted. Sure. And because I would say, I hit my smile. And I've had friends come up and say, John, your first smile, we love your smile. [00:48:23] But I didn't love my smile. And until I, not up here, not in my head, but in my heart, accepted my smile. I couldn't move forward. I couldn't heal. And once I accepted my new smile, I found joy. I found that I could love myself. [00:48:46] And what's funny is when you get to that point, [00:48:49] yeah. [00:48:50] John: You overcome whatever that thing is that's holding you back. [00:48:53] Yeah. [00:48:54] John: And you want to share it with every person you come in contact with. [00:49:00] Danielle: Yeah. You are the love you're seeking. [00:49:02] John: Yes. Yes. And you are your acceptance. [00:49:05] Danielle: It reminds me of, something. He said in an interview, in, A New Earth, but author Eckert Tolle said that right before his essential death of the, he called it the death of his ego, but we could call it enlightenment or rebirth. [00:49:19] But he remembers the last thing he said before he went to sleep was, I can't live with myself anymore. And it wasn't about in the interpretation , of , taking one's own life . but what he realized is that he couldn't live with the self that was hating him. He couldn't live with that self. [00:49:40] And that self never woke up. But he did. [00:49:45] John: Through my journey [00:49:46] Of coming to accept myself for who I am. I immediately see others. [00:49:53] Yeah. [00:49:53] John: How they're hiding. [00:49:54] Before they recognize it. And so my coaching is all about not saying, this is why you're hiding. [00:50:03] That's what's holding you back. [00:50:06] Danielle: What you said about once you, you see somebody's wall so clearly because you understand your own so well. My less eloquent way of saying that to clients, it's once you smell bullshit, you can't unm it. It's the scent in the air and you're like, huh, what am I smelling? [00:50:23] Oh, it's bullshit. Well, John, I would love to know your, don't cut your own bang moment. [00:50:30] John: I'm backstage. There are a thousand people in the audience and I had theatrical training I had a talk memorized. It had to be 12 minutes long. [00:50:39] I'm doing a magic trick with other people that are coming up stage. I needed to control that. I got there early the morning of the TED Talk and helped the guys focus the lights so that it looked better. I'm all in. I want to shine in this TED Talk. , I remember I'm going up on stage and I'm saying, to the cherry picker operator, can I give you a hand? Because I have lighting experience. And I expected the presenter come and say, no, John, you're the actor. Go in your, the green room and there's some donuts and coffee , and we'll call you already, but you didn't. She knew that I was there to make the entire event better. And she let me do it, [00:51:18] That's awesome. [00:51:19] John: This is my first real speech. Okay, in front of a thousand people. And I knew that I had a limited time to get the audience on my side. [00:51:30] Get the audience engaged. How was I gonna be able to break their, going through their phone, talking to a neighbor, drinking, eating, snacking in a full day of speech? [00:51:41] Yeah. [00:51:43] John: So I said, I wanna go first. And everybody has said, great, but we don't, you can go first. And right before the mc went on stage to introduce me. I did a magic trick war. I turned Monopoly money into real money and then back again. [00:52:00] So as a magician, everything was possible. I turned monopoly into real money, but then I realized that's actually called counterfeiting he stays out for like seven seconds. I did that to the mc and now he just saw a miracle happen. [00:52:16] So he turns around and walks on stage beaming, and he told that story to the audience and said, Hey guys, your next speaker just did a miracle. He turned monopoly money into real money in front of my eyes. Pay attention to this cat. [00:52:37] Yeah. [00:52:38] John: So I walked on that stage. I had the love of everybody in the audience that everybody wanted to see what I was gonna do. [00:52:46] Everybody wanted to hear what I was gonna say, so I didn't have to warm up the audience. I got the mc to do it for me. Genius. And I do that every time I speak because it works but anyway, three quarters of the speech, I'm standing on my red circle and I'm delivering my talk. [00:53:08] And the front lights go out. [00:53:10] Danielle: Wait, you were three fours of the way done when they went out. [00:53:13] John: I'm standing in shadows. And my first reaction was, whoa. That Whoa. Got the lighting guy to realize, holy shit, I hit the wrong button, and he brought the lights slowly back up. [00:53:27] As the lights went back up, I went magic [00:53:32] and so I got an amazing laugh from the audience. [00:53:36] Because I cut the tension, I was doing improv. [00:53:38] I remember walking off stage and the producer of the event said, John, don't worry about, we'll edit that part out. And I said, don't you dare. That was my finest moment. Don't you dare edit that out. [00:53:54] I want that in the video. [00:53:57] She just smiled as I went back to the dressing room and sat down and then the adrenaline was like, whew. Walking out into the audience after the event and having strangers just come up to me and wanna hug me and say, holy cow, I resonate with your message. [00:54:18] And my message on the TED Talk was, treat people are different with respect to compassion. [00:54:23] That's what TED talks are all about. You want one key message and that was my message. [00:54:27] You never know, you might be in their shoes in an instant. [00:54:34] Danielle: I wanna add to that, another way to speak to the value of doing some self investigation, whether that's through journaling, through therapy, or seeking out a coach from someone like yourself is, because that expression of, treat other people the way you would wanna be treated. [00:54:53] What I know is that we don't treat ourselves all that well. A lot of us, many of us don't treat ourselves well, which is why accessing the compassion. Of treating others kindly is sometimes harder for us to find, jumping to criticism or judgment, because there's something we are rejecting in us. [00:55:13] So I think a way to do the thing you're saying , that beautiful treat others with kindness and compassion. The best way to do that is to look within. And I invite anybody listening to go to the show notes, visit John's website, seek out a coaching call, grab a copy of his book. There are resources that can help you be kinder to yourself, to lowering the walls, to lifting the veil, to seeing yourself in a new way, to performing the ultimate illusion, which is [00:55:52] to love yourself more fully exactly as you are so that we can be kinder to each other. 'cause we need that, we need a lot more kindness. [00:56:00] Thank you, John. Do we have the information we need for our listeners to get the special code? [00:56:06] John: John kipping.com. [00:56:08] Slash free gift. [00:56:11] Danielle: Ooh, you heard it here. John kipping.com/free gift. And this is only the gift for those of you who have listened this far. [00:56:20] So if you listen to the beginning and you just try to skip to the show notes, sorry. You ain't getting a gift. Thank you, John. [00:56:28] Thank you so much for joining me on this incredible episode of Don't Cut Your Own Bangs. I hope that you love listening because I thoroughly enjoyed making it. My favorite episodes are the ones where I get to learn something too. I'm also a listener. And benefiting from the wisdom and insights of all of the experts, creatives, performers, adventurers seekers that I get an opportunity to meet in this podcast format. [00:56:56] Don't forget to check out the show notes and please before you sign off , always remember rate, review, subscribe to the podcast when you interact with the podcast. It just helps send it out like a rocket ship to other people that are looking for the same value that you are. And it also helps create a conversation where I can continue to develop and cultivate something that benefits you more and is more fun for you to listen to. Feedback is great, and also if you just wanna throw a compliment, that's sweet too. But thank you so much for being here. [00:57:26] Your intention, your time mean the absolute world to me, and I hope you continue to have an incredible day. [00:57:32] ​

Today on Beating Cancer Daily, Saranne, the founder of the ComedyCures Foundation and a Stage IV cancer survivor for over 30 years, brings a much-needed lighthearted perspective to the realities of life with cancer. Through her signature humor and wisdom, she shares a laugh-out-loud colonoscopy joke and introduces listeners to the 31-Day Tumor Humor Challenge, designed to help reframe stressful cancer experiences. Saranne also discusses an inspiring Etsy poster that lists things we simply cannot control, encouraging listeners to identify and release these burdens, thereby finding greater healing and joy. With personal anecdotes about the controversial yet deeply meaningful decisions she made throughout her cancer journey, Saranne reminds everyone that humor and self-reflection go a long way in cultivating resilience on the toughest days. “My colonoscopy just confirmed that I'm beautiful inside and out.” ~SaranneToday on Beating Cancer Daily:·     Humor can be a powerful tool for coping with cancer procedures and stress·     The 31-Day Tumor Humor Challenge encourages finding laughter in daily cancer experiences·     Some things in life, such as others' opinions or the weather, are outside of our control and not worth our energy·     Letting go of what you can't control allows for more space to heal and enjoy meaningful moments·     It's important to critically evaluate advice and only keep what truly aligns with your own values·     Making bold or unconventional care decisions can be empowering and provide important life lessons to loved ones·     Having comic perspective helps foster resilience and lighten overwhelming situations·     Sharing your lists and humor can inspire others and build a supportive, positive community Ranked the Top 5 Best Cancer Podcasts by CancerCare News in 2024 & 2025, and #1 Rated Cancer Survivor Podcast by FeedSpot in 2024 Beating Cancer Daily is listened to in over 130 countries across 7 continents and features over 365 original daily episodes hosted by Stage IV survivor Saranne Rothberg.   To learn more about Host Saranne Rothberg and The ComedyCures Foundation:https://www.comedycures.org/ To write to Saranne or a guest:https://www.comedycures.org/contact-8 To record a message to Saranne or a guest:https://www.speakpipe.com/BCD_Comments_Suggestions To sign up for the free Health Builder Series live on Zoom with Saranne and Jacqui, go to The ComedyCures Foundation's homepage:https://www.comedycures.org/ Please support the creation of more original episodes of Beating Cancer Daily and other free ComedyCures Foundation programs with a tax-deductible contribution:http://bit.ly/ComedyCuresDonate THANK YOU! Please tell a friend whom we may help, and please support us with a beautiful review. Have a blessed day! Saranne 

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On this week's show Beth speaks with computational biologist Justine Debelius about the role of the microbiome. We first discussed a study she was involved in recently that identified how changes in colon cancer tumors can affect survival. Then, she described a large collaborative project she is currently working on to identify factors influencing the … Continue reading "The Tumor Microbiome Can Affect Cancer Survival"

In this episode, we review the high-yield topic of⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Benign Bone Tumors⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠from the Oncology section.Follow⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Medbullets⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbullets

In this episode, we review the high-yield topic of⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠Pancoast Tumor ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠from the Oncology section.Follow⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Medbullets⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbullets

Is your practice delivering optimal care for patients with rare solid tumors and championing team-based management? Credit available for this activity expires: 7/16/26 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/1002679?ecd=bdc_podcast_libsyn_mscpedu

Sir Mixaway. Pulling the dork. It lights up and extends. Tumor pot pie. Wymong? Wy Not Mong? Filling the Hootie Hole. She's got some juicy doubles. Great swelling moments. Pisstory. X-Men or Disney Beast? Yes. Where In the World is Carmen Sandiego, You Know I Wanna Date Her. Sharkagator. Many Tabs Died to Bring You This Information. Red Button, Green Button, With Tom. Private Movielicious with Nicole and more on this episode of The Morning Stream. Hosted on Acast. See acast.com/privacy for more information.

Sir Mixaway. Pulling the dork. It lights up and extends. Tumor pot pie. Wymong? Wy Not Mong? Filling the Hootie Hole. She's got some juicy doubles. Great swelling moments. Pisstory. X-Men or Disney Beast? Yes. Where In the World is Carmen Sandiego, You Know I Wanna Date Her. Sharkagator. Many Tabs Died to Bring You This Information. Red Button, Green Button, With Tom. Private Movielicious with Nicole and more on this episode of The Morning Stream. Hosted on Acast. See acast.com/privacy for more information.

BUFFALO, NY - July 16, 2025 – A new #research paper was #published in Volume 16 of Oncotarget on July 9, 2025, titled “A novel anti-human CD25 mAb with preferential reactivity to activated T regulatory cells depletes them from the tumor microenvironment.” In this study, researchers from the National Institute of Allergy and Infectious Diseases, led by first author Maja Buszko and corresponding author Ethan M. Shevach, discovered a new monoclonal antibody that selectively targets a subset of immune cells called regulatory T cells (Tregs). These cells, while normally important for preventing autoimmunity, also can block the body's ability to fight cancer by suppressing anti-tumor immune responses. This discovery could lead to novel cancer therapies that strengthen the immune system's capacity to attack tumors. The researchers identified an anti-CD25 monoclonal antibody with several atypical properties and named it 2B010. To evaluate its effects, they used humanized mice, laboratory mice that are engineered to carry human immune cells, to closely mimic how human immune systems respond to cancer. The treatment of these mouse models with 2B010 significantly decreased the number of Tregs in tumors and boosted the activity of CD8+ T cells, which are essential for killing cancer cells. Importantly, 2B010 worked without disrupting other key immune functions. Unlike traditional Anti-CD25 antibodies, it did not interfere with interleukin-2 (IL-2) signaling, which is essential for the growth and activity of effector T cells that fight cancer. “2B010 also had no effect on IL-2 induced STAT5 phosphorylation or CD4+ T cell proliferation in vitro while both were blocked by Clone D1 further supporting the view that 2B010 does not recognize the IL-2 binding site.” This finding is especially significant because high levels of Tregs in tumors are associated with poor outcomes in many cancers. By specifically removing these cells, 2B010 may help overcome one of the main barriers to current immunotherapy approaches. Its ability to preserve IL-2 signaling could also make it safer and more effective when used alone or in combination with existing therapies such as immune checkpoint inhibitors. While the 2B010 antibody showed strong effects in reducing Tregs and boosting immune cell activity, the study did not observe changes in tumor size in these models. Researchers suggest this may be due to limitations in the preclinical systems used, such as the lack of tumor-specific T cells in humanized mice. Nevertheless, these findings demonstrate that 2B010 has a unique mechanism of action that could complement other cancer immunotherapies in future clinical trials. In conclusion, the development of 2B010 is a promising step toward selectively disrupting the immune suppressive environment in tumors. As researchers continue to refine and test this antibody, it could become a powerful tool for enhancing the effectiveness of cancer treatments and improving outcomes for patients. DOI - https://doi.org/10.18632/oncotarget.28752 Correspondence to - Ethan M. Shevach - eshevach@Niaid.NIH.gov Video short - https://www.youtube.com/watch?v=2NJcGsI7WXA Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28752 Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ Keywords - cancer, Treg, CD25, TME, mAb, GVHD To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM

In this episode, we review the high-yield topic of⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Malignant Breast Tumors⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠from the Oncology section.Follow⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Medbullets⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbullets

In this episode, we review the high-yield topic of⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Tumor Suppressor Genes⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠from the Oncology section.Follow⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Medbullets⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbullets

Full article: Pericardial Fat and Primary Tumor Radiomics for Predicting Occult N2 Disease and Survival in Clinical Stage I Non-Small Cell Lung Cancer: Multicenter Study With Biologic Correlation Kamyar Ghabili, MD, discusses the AJR article by Huang et al. exploring a predictive radiomics model in non-small cell lung cancer.

LCC in Portuguese: Virtual Tumor Board - EGFR NSCLC by IASLC

Dr. Evan Noch interviews Dr. Akshitkumar Mistry about his and his team's recent manuscript entitled "A clinically annotated transcriptomic atlas of nervous system tumors", published online in Neuro-Oncology in May 2025 Link to the paper: https://academic.oup.com/neuro-oncology/advance-article/doi/10.1093/neuonc/noaf130/8151442

Patrick and Chris wrap up season 25 and talk about their thoughts over all on the season.Email: tribalcouncilpodcast@gmail.com

In this episode of The Matt Feret Show I interview pain management pioneer Dr. Mitchell Yass. Dr. Yass is a physical therapist with over thirty years of experience treating individuals with chronic and episodic pain. Dr. Yass shares how he became disillusioned with traditional methods of treating chronic pain through his experience as a physical therapist and why he decided to develop his unique approach to pain management. He also shares expert advice and guidance to those questioning their experience with chronic pain treatment. Watch this episode on YouTube.Introduction to Dr. Mitchell Yass with Matt Feret [1:09]Dr. Mitchell Yass' Tumor and Recovery [05:41]Dr. Mitchell Yass' Perspective on the Root of Chronic Pain [13:23]The Yass Method of Pain Management with Dr. Mitchell Yass [28:07]Conclusion and Final Message with Matt Feret and Dr. Mitchell Yass [59:03]Connect with me via the podcast website, LinkedIn, Facebook, and Instagram.Check out Dr. Yass' YouTube, LinkedIn, Amazon bookstore, and The Yass Method website. Hosted on Acast. See acast.com/privacy for more information.

Equine lumps and bumps can appear alike whether they're benign or cancerous — and…

Hey Yo! This week we're joined by a personal favorite, Indy Wrestler, Buzzsaw Samuels! We talk Workaholics! Booker T! Heavy Metal Wrestling! Great Scott! The Tumor that altered his life and wrestling career! The Drive to Keep wrestling! New Texas Pro! And so much more! Enjoy! This episode is sponsored by Opie The Indian Ringneck ! Make sure to grab some Opie merch at www.opiethevip.store and follow Opie on all social media platforms!Big Thank You to Breakaway Brewing Company for sponsoring this episode! Breakaway Brewing Company is a cycling-themed brewery and gastropub located at 1518 East Grayson St in San Antonio Tx! The brewery offers a variety of beers which are all Tall Can Approved! Find em on Facebook and Instagram @breakawaybrewingsa !

What if a mouse could help shape the future of cancer treatment? In this episode of Sounds of Science, host Mary Parker speaks with Julia Schüler, DVM, PhD, Research Director and Therapeutic Area Lead for Oncology at Charles River. Julia shares how patient-derived xenograft (PDX) models—often described as “avatars” of human tumors—are transforming preclinical oncology research. From preserving tumor heterogeneity to improving translational relevance, PDX models are accelerating the discovery of more effective, personalized therapies. Tune in as we explore how these advanced models are driving innovation across the drug development pipeline—from target discovery to clinical trial design.Show NotesPDX Tumor Organoids : A New Tool in Drug Discovery Testing Realm Organoids: Some Assembly Required Patient-Derived Xenografts- PDX Models 3D Tumor Models In Vitro PDX Assays 

In this episode of Lung Cancer Considered, host Dr. Stephen Liu moderates a Virtual Tumor Board case with Dr. Chunxia Su and Dr. Collin Blakely. The case explores resectable EGFR NSCLC.

UCSF oncologist Dr. Jonathan Chou discusses how genetics and genomics are transforming the diagnosis and treatment of prostate cancer. He explains how inherited and acquired mutations—especially in DNA repair genes like BRCA2—can impact both cancer risk and treatment decisions. Dr. Chou outlines how UCSF researchers use tumor and blood-based biopsies to identify key mutations and genomic features that help tailor care for each patient. Examples include how genomic scores can predict response to radiation and how targeted therapies like PARP inhibitors benefit patients with specific mutations. The talk highlights the growing role of precision medicine in guiding individualized treatment plans based on the unique genetic profile of each patient's cancer. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 40798]

In this episode, Saranne invites you to join her for a lighthearted and informative discussion on the importance of having our affairs in order, even before a cancer diagnosis. With her signature humor and personal anecdotes, Saranne emphasizes the importance of wills, healthcare proxies, and durable power of attorney, while also sharing a humorous joke and offering practical tips on finding legal assistance. Tune in to discover how laughter can be found even in serious topics and how taking care of our legal affairs can bring peace of mind during challenging times.Ranked the Top 5 Best Cancer Podcasts by CancerCare News in 2024 & 2025, and #1 Rated Cancer Survivor Podcast by FeedSpot in 2024 Beating Cancer Daily is listened to in over 130 countries on 7 continents and has over 365 original daily episodes hosted by Stage IV survivor Saranne Rothberg!   To learn more about Host Saranne Rothberg and The ComedyCures Foundation:https://www.comedycures.org/ To write to Saranne or a guest:https://www.comedycures.org/contact-8 To record a message to Saranne or a guest:https://www.speakpipe.com/BCD_Comments_Suggestions To sign up for the free Health Builder Series live on Zoom with Saranne and Jacqui, go to The ComedyCures Foundation's homepage:https://www.comedycures.org/ Please support the creation of more original episodes of Beating Cancer Daily and other free ComedyCures Foundation programs with a tax-deductible contribution:http://bit.ly/ComedyCuresDonate THANK YOU! Please tell a friend whom we may help, and please support us with a beautiful review. Have a blessed day! Saranne 

Send us a textsoreadyforhealth.com (to book a consult)https://soreadyforhealth.podia.com/ (to register for my 3 month full body detox program)Support the show

Criminal Complaint Filed Over 'Warp Speed Cancer' (01:00:45 – 01:07:05)A complaint filed in France alleges mRNA vaccines caused deadly turbo cancers, implicating global health agencies while ignoring U.S. officials who enabled vaccine rollout. The term 'Warp Speed Cancer' is used to link aggressive cancers with the vaccine campaign.FDA Study Finds Excess DNA in COVID Vaccines (01:12:06 – 01:14:00)An FDA study confirms high levels of DNA contamination in Pfizer's mRNA vaccine, raising concerns over cancer risk and regulatory negligence. Critics compare the lax response to how pollution or car emissions would be handled.COVID Vaccine Removed from CDC Schedule for Children (01:25:54 – 01:27:49)RFK Jr. announces removal of COVID vaccines from the CDC schedule for healthy children and pregnant women, though skepticism is expressed over the true intent and lingering influence of vaccine advocates.CDC Panel Head Accused of Downplaying Vaccine Injuries (01:33:12 – 01:36:50)The new CDC vaccine panel head is criticized for opposing pauses on J&J shots and ignoring adverse event reports, leading to claims of pro-vaccine bias and lack of transparency about injury risks.Cargo Ship Fire Tied to EV Battery Hazards (01:53:00 – 01:59:30)An EV-laden cargo ship sinks after a prolonged fire, raising environmental concerns over lithium battery safety and whether such incidents are factored into EVs' environmental impact.Tesla Robo-Taxi Glitches Spark Regulatory Scrutiny (02:00:36 – 02:07:42)Videos show Tesla's driverless taxis behaving erratically, including stopping in intersections and veering off course. Observers criticize the premature rollout and ineffective safety measures.Markets Shrug Off U.S.-Israel Strike on Iran (02:25:30 – 02:27:04)Gold, silver, oil, and Bitcoin show minimal reaction to joint U.S.-Israel strikes, suggesting either disbelief in the severity of events or market manipulation by major financial actors.Christian Zionism Criticized as Political Idolatry (02:48:33 – 02:52:57)Christian Zionism is condemned as a distortion of theology, accused of leading believers to support war and foreign interventions at the expense of persecuted Christian communities.Pro-Israel Loyalty Test in Conservative Politics (02:52:58 – 03:01:38)Conservative figures are accused of prioritizing loyalty to Israel over American interests. A generational shift is predicted as younger conservatives push back against foreign entanglements.BIS vs IMF: Stablecoin Suppression and CBDC Agenda (03:01:39 – 03:03:04)The BIS targets stablecoins in what's described as a battle over who will control future digital money, with CBDCs positioned as tools of global financial dominance.Bitcoin Seen as Hedge Against Fiat Collapse (03:03:05 – 03:07:01)Extreme Bitcoin price forecasts are discussed in the context of fiat currency debasement, with Bitcoin framed as a finite refuge from an increasingly unstable monetary system.Self-Driving Cars as Surveillance and Control Tools (03:13:14 – 03:18:00)Explores how autonomous vehicles collect and transmit driver data, affect social credit scores, and raise concerns about accountability, privacy, and control.War Powers Debate: Trump, Iran, and Congressional Authority (03:18:01 – 03:24:17)Critiques Trump's bombing of Iran without Congressional approval and rebuts claims by Mike Johnson and J.D. Vance that the War Powers Resolution limits presidential authority.MAGA Civil War: Candace Owens vs. Trump on Vaccines and Israel (03:24:18 – 03:29:55) Candace Owens distances herself from Trump over foreign policy while she gave him a pass on Warp Speed vaccines, with commentary on her past praise and growing populist pushback.Trump's Nobel Peace Prize Nomination Mocked (03:30:40 – 03:31:35) Trump is nominated for a Nobel Peace Prize following the Iran ceasefire, provoking ridicule given his role in launching strikes days earlier.Mark Levin vs. Steve Bannon: Neocon Populist Feud over Israel (03:34:20 – 03:39:01)Levin calls for escalated military support for Israel, while Bannon and populist circles reject U.S. involvement. The rift signals deeper ideological divides on the right.Damage from Iranian Missile Strikes on Israel (03:45:10 – 03:47:55)Reports and footage highlight destruction caused by Iranian retaliation, while commentary accuses elites of profiting from wars at civilian expense.Iranian Officials Reported Dead Resurface (03:48:40 – 03:50:35) High-ranking Iranian figures previously declared dead by Israeli sources are shown to be alive, raising doubts about the success of targeted strikes.Follow the show on Kick and watch live every weekday 9:00am EST – 12:00pm EST https://kick.com/davidknightshow Money should have intrinsic value AND transactional privacy: Go to https://davidknight.gold/ for great deals on physical gold/silver For 10% off Gerald Celente's prescient Trends Journal, go to https://trendsjournal.com/ and enter the code KNIGHT Find out more about the show and where you can watch it at TheDavidKnightShow.comIf you would like to support the show and our family please consider subscribing monthly here: SubscribeStar https://www.subscribestar.com/the-david-knight-showOr you can send a donation throughMail: David Knight POB 994 Kodak, TN 37764Zelle: @DavidKnightShow@protonmail.comCash App at: $davidknightshowBTC to: bc1qkuec29hkuye4xse9unh7nptvu3y9qmv24vanh7Become a supporter of this podcast: https://www.spreaker.com/podcast/the-david-knight-show--2653468/support.

Support your health journey with our private practice! Explore comprehensive lab testing, functional assessments, and expert guidance for your wellness journey. Find exclusive offers for podcast listeners at nutritionwithjudy.com/podcast. _____Dr. Michael Karlfeldt and I sit down and talk about alternative cancer treatments. Is chemotherapy and radiation the best treatment? Is any food better than none while going through chemotherapy? What about exercise? Movement? Michael Karlfeldt, ND, PhD, has been in clinical practice since 1987 and runs an integrative medicine center, The Karlfeldt Center, in Boise, Idaho. Dr. Karlfeldt and his staff pride themselves on being compassionate cancer warriors focusing on cutting edge integrative cancer therapies working with international leaders to provide metabolic, genetic, and nutritional solutions to cancer while triggering cancer cell death through targeted oxidation. Dr. Karlfeldt's passion to promote Natural Health publicly has lead him to be a sought after lecturer, writer, and educator. Dr. Karlfeldt believes in the innate intelligence and healing power of the body and that if it is properly supported spiritually, emotionally and nutritionally it can find its way back to health. Dr. Karlfeldt IntroChemotherapy and Radiation for CancerImmune System's Role Post-Cancer TreatmentCancer Stem CellsIntegrative Cancer TherapyToxins, Tumors, and Genetics in CancerMost Common Toxins Turning on CancerDr. Karlfeldt and Chemo or Radiation for his Loved OnesThe Fear around CancerMitochondrial Health, Ketogenic Diets, DON, FastingWeight Loss with CancerFenbendazole, Ivermectin, Parasites, P53, Cell DeathProphylactic (Preventive) UseMind Body, Trauma and CancerThe Greatest Integrative Tool for CancerThe Biggest 3 Levers for CancerImportance of Muscle Mass_____EPISODE RESOURCES1) The Karlfeldt Center2) A Better Way to Cancer Book3) Integrative Cancer Solutions Podcast4) Integrative Lyme Solutions Podcast5) Dr. K  Show Podcast6) NwJ's Private Practice_____WEEKLY NEWSLETTER 

Criminal Complaint Filed Over 'Warp Speed Cancer' (01:00:45 – 01:07:05)A complaint filed in France alleges mRNA vaccines caused deadly turbo cancers, implicating global health agencies while ignoring U.S. officials who enabled vaccine rollout. The term 'Warp Speed Cancer' is used to link aggressive cancers with the vaccine campaign.FDA Study Finds Excess DNA in COVID Vaccines (01:12:06 – 01:14:00)An FDA study confirms high levels of DNA contamination in Pfizer's mRNA vaccine, raising concerns over cancer risk and regulatory negligence. Critics compare the lax response to how pollution or car emissions would be handled.COVID Vaccine Removed from CDC Schedule for Children (01:25:54 – 01:27:49)RFK Jr. announces removal of COVID vaccines from the CDC schedule for healthy children and pregnant women, though skepticism is expressed over the true intent and lingering influence of vaccine advocates.CDC Panel Head Accused of Downplaying Vaccine Injuries (01:33:12 – 01:36:50)The new CDC vaccine panel head is criticized for opposing pauses on J&J shots and ignoring adverse event reports, leading to claims of pro-vaccine bias and lack of transparency about injury risks.Cargo Ship Fire Tied to EV Battery Hazards (01:53:00 – 01:59:30)An EV-laden cargo ship sinks after a prolonged fire, raising environmental concerns over lithium battery safety and whether such incidents are factored into EVs' environmental impact.Tesla Robo-Taxi Glitches Spark Regulatory Scrutiny (02:00:36 – 02:07:42)Videos show Tesla's driverless taxis behaving erratically, including stopping in intersections and veering off course. Observers criticize the premature rollout and ineffective safety measures.Markets Shrug Off U.S.-Israel Strike on Iran (02:25:30 – 02:27:04)Gold, silver, oil, and Bitcoin show minimal reaction to joint U.S.-Israel strikes, suggesting either disbelief in the severity of events or market manipulation by major financial actors.Christian Zionism Criticized as Political Idolatry (02:48:33 – 02:52:57)Christian Zionism is condemned as a distortion of theology, accused of leading believers to support war and foreign interventions at the expense of persecuted Christian communities.Pro-Israel Loyalty Test in Conservative Politics (02:52:58 – 03:01:38)Conservative figures are accused of prioritizing loyalty to Israel over American interests. A generational shift is predicted as younger conservatives push back against foreign entanglements.BIS vs IMF: Stablecoin Suppression and CBDC Agenda (03:01:39 – 03:03:04)The BIS targets stablecoins in what's described as a battle over who will control future digital money, with CBDCs positioned as tools of global financial dominance.Bitcoin Seen as Hedge Against Fiat Collapse (03:03:05 – 03:07:01)Extreme Bitcoin price forecasts are discussed in the context of fiat currency debasement, with Bitcoin framed as a finite refuge from an increasingly unstable monetary system.Self-Driving Cars as Surveillance and Control Tools (03:13:14 – 03:18:00)Explores how autonomous vehicles collect and transmit driver data, affect social credit scores, and raise concerns about accountability, privacy, and control.War Powers Debate: Trump, Iran, and Congressional Authority (03:18:01 – 03:24:17)Critiques Trump's bombing of Iran without Congressional approval and rebuts claims by Mike Johnson and J.D. Vance that the War Powers Resolution limits presidential authority.MAGA Civil War: Candace Owens vs. Trump on Vaccines and Israel (03:24:18 – 03:29:55) Candace Owens distances herself from Trump over foreign policy while she gave him a pass on Warp Speed vaccines, with commentary on her past praise and growing populist pushback.Trump's Nobel Peace Prize Nomination Mocked (03:30:40 – 03:31:35) Trump is nominated for a Nobel Peace Prize following the Iran ceasefire, provoking ridicule given his role in launching strikes days earlier.Mark Levin vs. Steve Bannon: Neocon Populist Feud over Israel (03:34:20 – 03:39:01)Levin calls for escalated military support for Israel, while Bannon and populist circles reject U.S. involvement. The rift signals deeper ideological divides on the right.Damage from Iranian Missile Strikes on Israel (03:45:10 – 03:47:55)Reports and footage highlight destruction caused by Iranian retaliation, while commentary accuses elites of profiting from wars at civilian expense.Iranian Officials Reported Dead Resurface (03:48:40 – 03:50:35) High-ranking Iranian figures previously declared dead by Israeli sources are shown to be alive, raising doubts about the success of targeted strikes.Follow the show on Kick and watch live every weekday 9:00am EST – 12:00pm EST https://kick.com/davidknightshow Money should have intrinsic value AND transactional privacy: Go to https://davidknight.gold/ for great deals on physical gold/silver For 10% off Gerald Celente's prescient Trends Journal, go to https://trendsjournal.com/ and enter the code KNIGHT Find out more about the show and where you can watch it at TheDavidKnightShow.comIf you would like to support the show and our family please consider subscribing monthly here: SubscribeStar https://www.subscribestar.com/the-david-knight-showOr you can send a donation throughMail: David Knight POB 994 Kodak, TN 37764Zelle: @DavidKnightShow@protonmail.comCash App at: $davidknightshowBTC to: bc1qkuec29hkuye4xse9unh7nptvu3y9qmv24vanh7Become a supporter of this podcast: https://www.spreaker.com/podcast/the-real-david-knight-show--5282736/support.

Lots of great questions, some including elective surgery, international politics, and more insanity. Membership Specials https://swolenormousx.com/membershipsDownload The Swolenormous App https://swolenormousx.com/swolenormousappMERCH - https://papaswolio.com/Watch the full episodes here: https://rumble.com/thedailyswoleSubmit A Question⁠ For The Show: https://swolenormousx.com/apsGet On Papa Swolio's Email List: https://swolenormousx.com/emailDownload The 7 Pillars Ebook: https://swolenormousx.com/7-Pillars-EbookTry A Swolega Class From Inside Swolenormous X: https://www.swolenormousx.com/swolegaGet Your Free $10 In Bitcoin: https://www.swanbitcoin.com/papaswolio/   Questions? Email Us: Support@Swolenormous.com

What happens when you're told your child has over 1,000 tumors—and there's nothing more doctors can do? In this powerful episode, we sit down with Nat and Daniel Nowak to hear the miraculous healing story of their son Murphy, who was diagnosed with stage 4 high-risk neuroblastoma. Against all odds, and through a journey marked by faith, prayer, and relentless love, Murphy's body defied every expectation.This conversation is a testimony to the power of hope and the God who still heals. Whether you're in a season of doubt or simply need your faith stirred, this episode will move you deeply.

A mysterious disease called acute flaccid myelitis (AFM) has been appearing in emergency rooms for about a decade. The disease has caused otherwise healthy children to lose the ability to move their arms and legs, and some become completely paralyzed. AFM is caused by a virus that's a cousin of the polio virus, earning it the nickname "the new polio.” Journalist and physician Eli Cahan joins Host Flora Lichtman to explain what doctors have been observing, the research efforts toward developing a vaccine, and what this emerging disease reveals about our readiness for future outbreaks and pandemics.Read Cahan's article about what fighting this “new polio” might look like as our healthcare infrastructure gets dismantled.And, learning more about some non-cancerous cells may help researchers better understand how cancer progresses. When you think about how cancer spreads in the body, you're probably thinking about cancer cells—they divide uncontrollably, form into tumors, and hide from the immune system. So, it makes sense that studying the behavior of these cells is critical to our understanding of cancer. But now, researchers are looking more closely at the non-cancerous cells that co-exist within tumors and the surrounding tissues. They make up what's called the “colocateome.” Taking this more holistic approach to cancer research may help explain why some treatments don't work for all patients, and eventually may lead to more effective therapies. To better understand this expanding field, Host Ira Flatow talks with Sylvia Plevritis, a Stanford University cancer researcher. Guests:Dr. Eli Cahan is a journalist and physician based in Boston, Massachusetts.Dr. Sylvia Plevritis is a professor of biomedical data science and radiology at Stanford University.Transcript is available on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.