Podcasts about Angstrom

Of All the Creepy Stuff They Have Done Conquest Whispering Sweet Sweet Nothings to Mark was the Creepiest. This week on the podcast, Brian and Darryl, are talking about Daredevil: Born Again, the Invincible season 3 Finale, and the latest episode of Reacher on Prime! Episode Index Intro: 0:07 Daredevil: Invincible: Reacher: Daredevil: Born Again (Disney) Episode 3: The Hollow of the Hand Out of 5 White Tigers are Endangered Darryl: 3.65/5 Brian: 3.87/5 Director: Michael Cuesta  Writer: Jill Blankenship Air Date: March 11, 2025 Summary: In Daredevil: Born Again Season 1, Episode 3, “The Hollow of the Hand,” Matt Murdock (Charlie Cox) defends Hector Ayala (Kamar de los Reyes), the vigilante White Tiger, accused of murdering a police officer, in a trial that exposes deep-seated corruption within the NYPD and Mayor Wilson Fisk's (Vincent D'Onofrio) administration. As Officer Powell attempts to frame Matt for interfering with police matters, a key witness, Nicky Torres, is pressured into recanting testimony about police misconduct. In a bold courtroom strategy, Matt reveals Hector's identity as White Tiger, shifting jury perception when officers acknowledge his past aid to law enforcement. Though Hector is acquitted, his post-trial assassination by a gunman wearing a Punisher skull emblem hints at a broader conspiracy. Meanwhile, tensions rise between Fisk and his wife, Vanessa (Ayelet Zurer), over their conflicting visions for controlling New York's underworld. Balancing legal drama with intense action, the episode explores themes of justice, corruption, and the high cost of vigilantism, setting the stage for even greater conflicts ahead. Invincible (Prime Video) Season 3 Out of 10 Mark Grayson IS GONNA FIGHT?!?! Darryl: 8.5/10 Brian: 8.57/10 Episode 8: I Thought You’d Never Shut Up Out of 5 Only the Lonely Darryl: 4.85/5 Brian: 4.8/5 Director: Sol Choi Writer: Robert Kirkman Air Date: March 6, 13025 Summary: As Mark and Conquest engage in combat, Oliver and Eve attempt to intervene but are incapacitated. Nonetheless, Eve temporarily releases her mental blocks, allowing her to reconstruct her body and burn Conquest’s skin off before Mark defeats and seemingly kills him. Mark awakens in the hospital, where Debbie apologizes for bringing him into this world, though Mark says he does not blame her. At Rex’s funeral, Rudy changes his name to Rex to honor him. As the world rebuilds, Livingston builds up an army of Sequid-possessed humans, a group of aliens finds Battle Beast and the Technicians begin to use Angstrom to claim a new world. Cecil reveals to Donald he has captured a comatose Conquest and placed him in an underground prison, intending to interrogate him about the Viltrum Empire. Mark tells Oliver he was right to kill people, promising to do so to anyone who threatens their family. Darkblood meets with a demon overlord to help reinstate him as Hell’s ruler by exploiting a powerful being on Earth. Reacher (Prime) Episode 6: Smoke on the Water Out of 5 Lingering Glances Darryl: 3.75/5 Brian: 4.2/5 Director: Sam Hill Writer: Scott Sullivan Air Date: March 13, 2025 Summary: Quinn meets with Zachary and accuses him of unknowingly having an ATF mole inside. Due to the retrograde amnesia caused by Reacher, Quinn has no memory of him and introduces himself to him using his alias McCabe. Quinn meets with a Russian mobster; Reacher discovers Quinn is in danger. Afterward, Reacher drives Richard into town to meet with Duffy and return her badge; Reacher and Duffy kiss, and Richard realizes that Reacher is a mole. Quinn sends men to kill everyone investigating him, including Neagley; Neagley kills them and tells Reacher. Quinn arrives at Zachary’s house to question him about the U.S. Army investigating him; Zachary tells him that said unit was Reacher’s. Quinn sends Paulie to kill Reacher, but he escapes, leading to a chase. Reacher kills all the men in the forest except Paulie and takes refuge in a laundromat. Quinn punishes Zachary by forcing Richard to play Russian roulette. Reacher and Duffy search for Teresa in Port Rome, but Harley claims that Quinn changed everything after Reacher escaped. Reacher and Duffy travel to Los Angeles. Contact Us The Infamous Podcast can be found wherever podcasts are found on the Interwebs, feel free to subscribe and follow along on social media. And don't be shy about helping out the show with a 5-star review on Apple Podcasts to help us move up in the ratings. @infamouspodcast facebook/infamouspodcast instagram/infamouspodcast stitcher Apple Podcasts Spotify Google Play iHeart Radio contact@infamouspodcast.com Our theme music is ‘Skate Beat’ provided by Michael Henry, with additional music provided by Michael Henry. Find more at MeetMichaelHenry.com. The Infamous Podcast is hosted by Brian Tudor and Darryl Jasper, is recorded in Cincinnati, Ohio. The show is produced and edited by Brian Tudor. Subscribe today!

「純水ウルトラマイクロミスト加湿器 angstrom「A-600S」やAmazonギフト券が当たるプレゼントキャンペーンが@DIMEでスタート！」　@DIMEでは、読者の皆さまに より便利で役立つ情報 をお届けできるよう、新しく パーソナライズ機能 を追加しました。

Invincible vs Conquest! Darkblood and a mysterious devil. Angstrom has a brand new arm!https://www.twitch.tv/geekvariantshttps://spotifyanchor-web.app.link/e/wtvTDi0kUzbhttps://www.facebook.com/groups/176901704469900https://www.instagram.com/geekvariants/

All The Marks Than You Can Shake A Stick At This week on the podcast, Brian and Darryl are talking about Reacher Season 3, so far. And The Invincible War… no Episodes 5 and 6 NEVER happened. Episode Index Intro: 0:07 Invincible: 9:54 Reacher: 26:28 Invincible (Prime Video) Out of 5 The Invincible War Was Crazys Darryl: 4.45/5 Brian: 4.5/5 Episode 7: What Have I Done? Director: Haylee Herrick Writer: Robert Kirkman Air Date: March 6, 2025 Summary: Angstrom sends his Invincible variants to destroy Earth and tarnish Mark’s image. The GDA, the Guardians, and Earth’s heroes are overwhelmed and suffer heavy losses. Eve is incapacitated; Rex sacrifices himself to save Rudy, Monster Girl, and Bulletproof; Darkwing II is presumed dead; and the Immortal, Kate, Samson, and Shapesmith are wounded. When the surviving Invincibles turn on Angstrom, he traps them on a desolate Earth before battling Mark. Mark overpowers and nearly kills Angstrom, but he escapes to the Technicians, advanced cybernetic surgeons who previously healed him. Angstrom orders them to fix his wounds, but they refuse, demanding he submit to their will. In the aftermath of Angstrom’s attack, an aged Viltrumite envoy named Conquest arrives to survey Mark’s subjugation of Earth for the Viltrum Empire and is disappointed by his lack of progress. Devastated by the destruction and deaths directed at him, Mark charges at Conquest to vent his rage. Reacher Season 3: Episodes 1-5 (Prime Video) Out of 10 Out of 10 Reacher is So Unstoppable, Gravity is Just a Suggestions Darryl: 7/10 Brian: 7.76/10 Episode 1: Persuader Director: Sam Hill Writer: Scott Sullivan Air Date: February 20, 2025 Summary: In Maine, Reacher saves a man from a kidnapping attempt by shooting the kidnapper. When Reacher accidentally shoots a cop, a police chase ensues. The man, whose name is Richard Beck, reveals to Reacher that someone had kidnapped him before and that his father only paid the ransom when his ear was amputated. Richard takes Reacher home to see his father, Zachary Beck. Reacher meets with Zachary, who thanks him for saving his son but is suspicious of him. Zachary offers Reacher a job if he plays Russian roulette, which he does. Reacher is working undercover for Susan Duffy, a DEA agent who recruited him to find a missing undercover agent, Teresa Daniels, in exchange for helping Reacher deal with a previous nemesis, Lieutenant Colonel Francis Xavier Quinn. To put Reacher undercover, they stage Richard’s kidnapping, with the kidnapper and the cop being DEA agents (Steven Eliot and Guillermo Villanueva) working with Duffy. Reacher sneaks into the garage at night, where he finds and reveals to Duffy that Teresa was there. Episode 2: Truckin' Director: Sam Hill Writer: Penny Cox Air Date: February 20, 2025 Summary: When Duffy learns from Reacher that Teresa is in danger, she beats up the bodyguard they are holding captive to find out what they plan to do with Teresa, but the bodyguard claims he does not know. Reacher has a brief scuffle with hulking bodyguard Paulie before Zachary’s head guard, Chapman Duke, sends Reacher to check out the hijacked cars. Reacher calls Duffy to tell her that it may be a problem for the kidnapping story; Duffy goes to the car yard to retrieve one of the cars. One of Zachary’s associates, Angel Doll, notices the bodyguard’s car but doesn’t see Duffy changed the license plate. Duke orders Reacher to take a truck to New London, Connecticut. Reacher calls Neagley to investigate the people he works with. Reacher meets with Duffy to check the trailer for drugs or Teresa’s body, but they only find carpets. Back in Maine, Doll questions Reacher about his actions at the yard and in the kidnapping, and when Doll tries to tell Duke about his suspicions, Reacher slams his head onto a table, killing him. Episode 3: Number 2 with a Bullet Director: Gary Fleder Writer: Cait Duffy Air Date: February 20, 2025 Summary: After returning from New London, Reacher meets with Zachary over a message from Doll. Reacher tries to make him believe that his partners are trying to betray him and that they should kill them, but Zachary doesn’t listen. After this, Reacher tells Duffy that he has a car ready to go back to the warehouse where he killed Doll. When Reacher arrives at the meeting point, Duffy tells him she will go with him to find Teresa, to which Reacher reluctantly agrees. At the warehouse, Reacher and Duffy search for Teresa and clean up Doll’s remains; two men arrive, and Reacher and Duffy kill them. Duffy keeps Doll’s laptop. The next day, Reacher has to be with Richard in town. Reacher defends him from some thugs, and Richard tells him that Zachary’s boss, Julius McCabe, threatened him and his father. When Reacher returns home, he goes with Duke and Zachary to a cabin, the kidnapper’s hiding spot. Reacher takes the opportunity to kill Duke, fake a shootout and blow up the house; in the car, he wins over Zachary and becomes his number two. Episode 4: Dominique Director: Sam Hill Writer: Lillian Wang Air Date: February 27, 2025 Summary: Reacher heads to Duffy’s house after gaining Zachary’s trust. He discovers that Julius McCabe is Xavier Quinn, whom he believed to be dead. Following the revelation, Reacher tells Duffy how he received a new partner, Dominique Kohl, to investigate a case involving Gorowski. They eventually force Gorowski to tell them that he works for Quinn, selling state secrets because Quinn threatened his family. Reacher and Kohl, along with Anthony Frasconi, intercept one of Quinn’s buyers, a Syrian businessman, Safwan Qasim, whom they force to assist in capturing Quinn. Having evidence to prosecute him, Reacher allows Kohl to arrest Quinn. Quinn instead kidnaps Kohl. In his search for her, Reacher finds Frasconi dead in a house, and later finds Kohl’s bloody body hanging in a cabin; Quinn brutally murdered her. Reacher finds Quinn and shoots him in retaliation, apparently killing him. Back in the present, Zachary sends Reacher to a factory where they have located Doll’s laptop and where Duffy is. Reacher heads to the factory as three of Quinn’s men arrive there. Episode 5: Smackdown Director: Norberto Barba Writer: Scott Sullivan Air Date: March 6, 2025 Summary: When Reacher can’t contact Duffy, he calls Eliot to call the company’s number. When Eliot calls, a gunfight breaks out between Quinn’s men and Duffy and Villanueva; Reacher helps Duffy and Villanueva escape. At the cabin, the captive bodyguard takes advantage of Eliot’s mistake to kill him and escape. After discovering that the feds are spying on them, Quinn’s men move into the house. When Duffy finds Eliot dead and the bodyguard has escaped, she calls Reacher to tell him so and get him out of the house, but Reacher formulates a plan involving Villanueva. Duffy cuts the power and Reacher uses Villanueva as bait to kill the bodyguard. Back at the house, Zachary informs Reacher that Annette, the maid, was an ATF infiltrator and that Paulie has killed her. Reacher tells Duffy that several Feds are spying on them and that Quinn is dealing in firearms, not drugs. The next morning, Zachary informs Reacher that they have been summoned to a factory. Reacher and Zachary arrive there just as they are about to meet Quinn. Contact Us The Infamous Podcast can be found wherever podcasts are found on the Interwebs, feel free to subscribe and follow along on social media. And don't be shy about helping out the show with a 5-star review on Apple Podcasts to help us move up in the ratings. @infamouspodcast facebook/infamouspodcast instagram/infamouspodcast stitcher Apple Podcasts Spotify Google Play iHeart Radio contact@infamouspodcast.com Our theme music is ‘Skate Beat’ provided by Michael Henry, with additional music provided by Michael Henry. Find more at MeetMichaelHenry.com. The Infamous Podcast is hosted by Brian Tudor and Darryl Jasper, is recorded in Cincinnati, Ohio. The show is produced and edited by Brian Tudor. Subscribe today!

Ebuka, Chiagoziem and Oseghale are solemnly inspecting the wreckage from the multi-city, multi-dimension Invincible War. They share a moment of silence for those we lost on this week's 'Invincible', before assessing Angstrom's hatred for Mark, Mark's continued trauma and of course, the episode's last-minute party guest. You can support us here.Subscribe to our Newsletter.Also available on YouTube.Host: Ebuka NnamaniGuests: Chaigoziem and OseghaleProduction by: Bankole Imoukhuede

You’re a Creampuff Sensei Wolf! This week on the podcast, Brian and Darryl say goodbye to Cobra Kai! And welcome back to Invincible. Episode Index Intro: 0:07 Invincible: 5:31 Cobra Kai: 29:18 Invincible Season 3 Episodes 1-4 (Prime Video) Out of 10 Alan the Alien Rope-a-dopes Darryl: 7.5/10 Brian: 7.77/10 Episode 18: “You're Not Laughing Now” Summary: Three months after his battle with Angstrom, Mark continues training under Cecil's supervision to gain enough strength to compete with Viltrumites while avoiding Eve. Mark and Rex try to stop two thieves, Dropkick and Fightmaster, from stealing the Declaration of Independence but are attacked by Kate's brother, Multi-Paul, who tries to avenge his sister's death. Kate and the Immortal come out of retirement while Rae returns to the Guardians. William and Rick encourage Mark to confess his feelings and ask Eve out, but warn him against telling her about her future self. However, Mark lets it slip, leading Eve to reject him. Doc Seismic breaks out of confinement and kidnaps Earth's superheroes using giant underground creatures. When Mark and Eve fail to save the heroes, Cecil sends in Darkwing II and Reanimen to help, with Darkwing II recapturing Doc Seismic. Mark confronts Cecil for lying to him and working with Darkwing II and Sinclair, leading Cecil to trap him in the White Room, which was constructed to keep him safe from Mark. Allen and Nolan bond in prison while the Viltrumites begin testing Allen to determine the source of his newfound strength. • Writer: Simon Racioppa • Director: Jason Zurek Episode 19: “A Deal with the Devil” Summary: In a flashback, Cecil objects to his predecessor rehabilitating criminals. In the present, Mark destroys Reanimen deployed to stop him. Cecil activates a device installed in Mark's head matching the Atlantean kaiju's roars, causing him intense pain and preventing him from flying. Mark flees to the Guardians for help but Cecil arrives and attacks Mark with more Reanimen, prompting the Guardians to aid him. Rudy jams the signal that is harming Mark while Cecil, realizing his mistake, deactivates the Reanimen. A furious Mark threatens to kill Cecil should he approach him or his family, ending their working relationship. The Guardians break up, with Monster Girl, Rex, Rae, Bulletproof, and Rudy losing trust in Cecil, while the Immortal, Kate, Samson, and Shapesmith remain and are joined by Darkwing II. Cecil later reflects on his first meeting with Nolan and developing his personal code of doing anything to protect Earth while Mark and Eve reconcile and start a relationship. • Writer: Helen Leigh • Director: Haylee Herrick Episode 20: “You Want a Real Costume, Right?” Summary: Mark receives a new suit from Rosenbaum. After getting his own suit, Oliver names himself “Kid Omni-Man”, but Mark advises against it, explaining the destruction Nolan caused, before they join forces to stop Titan from breaking out Multi-Paul. Eve moves back in with her parents, promising not to use her powers at home if they become more accepting of her duties as a hero. Debbie forms a relationship with her colleague Paul and reveals to him Nolan, Mark, and Oliver's secret identities, angering Mark. The Maulers break into a missile silo, planning to launch an EMP device to destroy the world's communication systems, and incapacitate the attacking Guardians. Mark destroys the missile while Oliver, against his and Debbie's wishes, kills the Maulers. He reveals to Mark his indifference to killing, believing Nolan may be right, worrying Mark. While talking with Oliver, Mark notices a floating orb-like drone spying on the Grayson household, which detonates in his hand as he catches it. Unbeknownst to him, the drone belongs to Angstrom, who survived his previous encounter with Mark. • Writer: Jay Faerber • Director: Sol Choi Episode 21: “You Were My Hero” Summary: Mark asks Rudy to analyze the drone, which he determines originated from Earth and was created by someone with vast resources. Mark confronts Cecil, believing he built it, but Cecil denies it. Later, while on a date with Eve, Fightmaster and Dropkick forcibly recruit Mark and bring him to their future, believing he can save their Earth from its tyrannical king, the Immortal. Driven mad by his immense power and immortality, he blames Mark for his eventual abandonment of Earth and demands he fight him to the death to bring him peace. Reluctantly, Mark fights and is eventually forced to kill the Immortal. Returning to the present, a shaken Mark finds solace with Eve. Meanwhile, Nolan faces execution until Allen breaks free, liberates their fellow inmates, gains Battle Beast's help in fending off the Viltrumites, and feigns defeat to spur Nolan into action. After breaking out, Allen suggests they flee before reinforcements arrive, but Nolan reveals the Viltrum Empire now consists of fewer than fifty pure-blooded members. • Writer: Tania Lotia • Director: Ian Abando These episodes delve deeper into Mark's struggles with his dual identity and the complex relationships he maintains with allies and adversaries. The series continues to explore themes of power, responsibility, and morality, keeping viewers engaged with its intricate storytelling and character development. Cobra Kai Season VI Episodes 11-15 (Netfilx) Season VI Part 3 Out of 10 Flaming Cigar Yacht Explosions Darryl: 9/10 Brian: 9.23/10 Cobra Kai The Series Out of 10 From an Illegal Kick to the Face to Best Friends Darryl: 9.25/10 Brian: 8.94/10 Episode 11: “Into the Fire” Summary: While their students plan for life after karate, Daniel and Johnny clash over reviving the Sekai Taikai. Kreese reconsiders his guiding principles. • Writer: Joe Piarulli & Luan Thomas • Director: Joel Novoa Episode 12: “Rattled” Summary: Sam and Robby turn to their friends for support as they train for the challenges ahead. Johnny and Carmen welcome a new addition to the team. • Writer: Bob Dearden • Director: Steven K. Tsuchida Episode 13: “Skeletons” Summary: As the moment of truth arrives, Daniel and Johnny confront their pasts. Then it's fight time as Robby battles Axel in the world karate championship. • Writer: Stacey Harman • Director: Josh Heald Episode 14: “Strike Last” Summary: The action heats up as the Valley's top fighters pit their courage against their rivals' speed and strength. But one last surprise changes everything. • Writer: Michael Jonathan Smith • Director: Jon Hurwitz & Hayden Schlossberg Episode 15: “Ex-Degenerate” Summary: The series finale delivers dramatic conclusions for key characters, including Johnny's victory in the Sekai Taikai tournament, Kreese's redemption, and heartfelt moments between Daniel and Johnny. • Writer: Josh Heald, Jon Hurwitz & Hayden Schlossberg • Director: Jon Hurwitz & Hayden Schlossberg These episodes provide a fitting conclusion to the series, resolving long-standing rivalries and character arcs. The final episode, “Ex-Degenerate,” in particular, offers a mix of resolution, drama, and a hopeful message of reconciliation. Contact Us The Infamous Podcast can be found wherever podcasts are found on the Interwebs, feel free to subscribe and follow along on social media. And don't be shy about helping out the show with a 5-star review on Apple Podcasts to help us move up in the ratings. @infamouspodcast facebook/infamouspodcast instagram/infamouspodcast stitcher Apple Podcasts Spotify Google Play iHeart Radio contact@infamouspodcast.com Our theme music is ‘Skate Beat’ provided by Michael Henry, with additional music provided by Michael Henry. Find more at MeetMichaelHenry.com. The Infamous Podcast is hosted by Brian Tudor and Darryl Jasper, is recorded in Cincinnati, Ohio. The show is produced and edited by Brian Tudor. Subscribe today!

Welcome back, nerds! Join your hosts Sarah Belmont and Will Polk as they navigate through a whirlwind of topics in this week's episode. They kick things off with a heartfelt message to those affected by the wildfires in California, sharing their thoughts and support for everyone impacted. As the conversation shifts, Sarah and Will dive into the potential TikTok ban and its implications for content creators and users alike, with Sarah clarifying her healthy relationship with the platform. (0:00)  The duo then transitions into an engaging discussion about upcoming movies for 2025, covering everything from "How to Train Your Dragon" live-action adaptation to the highly anticipated "Captain America 4" and "Thunderbolts." Will shares his excitement for "Wallace and Gromit: Vengeance Must Foul," while Sarah expresses her curiosity about Robert Pattinson's "Mickey 17." They also touch on the intriguing "Sinners," starring Michael B. Jordan, and the remake of "The Naked Gun" with Liam Neeson. (12:00) In the TV realm, they revisit "Invincible" Season 2, analyzing the final three episodes and discussing the show's strengths as a binge-watch. Sarah and Will reflect on the impactful storytelling and character development, particularly focusing on Mark and Debbie's relationship and the climactic showdown with Angstrom. (45:00) Looking ahead, they tease next week's conversation about "Cobra Kai" and the 2024 TV lineup. Stay tuned as they continue to explore the nerdy universe with their unique insights and humor. Join the conversation and follow our crew on Twitter @SceneNNerd, on Bluesky @SceneNNerd.bsky.social, friend us on Facebook, and follow us on Instagram and Threads @scene_n_nerd. Visit our website at www.scenennerdpodcast.com. Don't forget to rate, follow, and comment on Apple Podcasts, Spotify, YouTube, or wherever you get your podcasts! Donate to support those impacted by the wildfires in California or Hurricanes Helene, Milton and other large and small disasters around the country: https://www.redcross.org/donate/donation.html/

Today we're joined by Joseph Noorchashm, Founding Partner of Sorella Labs and Ludwig Thouvenin, Co-Founder of Sorella Labs. Today we're discussing MEV searcher profits!In this episode the five of us discuss: Why build MEV Angstrom Frequent Batch Auction Brontes deep dive Angstrom Dashboard demo Bid adjustmentsBuilder profits Concentrated AMM's Potential limitations Programmatic determinations Exchange open price endpoints Atomic arbs Profit margin across MEVObserved data set trends  Angstrom UI Wen launch? DEX focusCEX/DEX volume hot takes And much more—enjoy!—Chapters:(00:00) Introduction (02:40) Why build MEV (04:21) Angstrom (09:52) Frequent Batch Auction (12:03) Brontes deep dive (16:53) Angstrom dashboard demo (28:53) bid adjustment  (32:28) Builder profits (34:56) Brontes examples (43:39) Concentrated AMM's (44:36) 1INCH example (53:07) Limitations (57:43) Programmatic determinations (1:01:34) Exchange open price endpoints (1:08:18) Atomic arbs (1:12:34) Profit margin across MEV(1:19:24) Key findings/spicy takes(1:27:07) Observed data set trends  (1:35:40) Angstrom UI (1:38:53) Wen launch? (1:40:30) DEX focus(1:42:25) CEX/DEX volume hot takes (1:45:18) Chart crime (1:52:13) Outro —The Indexed Podcast discusses hot topics, trendy metrics and chart crimes in the crypto industry every 1st and 3rd Friday of the month - brought to you by wizards @hildobby @0xBoxer @sui414.Subscribe to our channel and leave a comment to help us make the pod better!Follow the Indexed Podcast on Twitter: https://twitter.com/indexed_pod—Follow Joseph here:https://x.com/jnoorchashm37Follow Ludwig here:https://x.com/0xvanbeethoven—DISCLAIMER: All information presented here should not be relied upon as legal, financial, investment, tax or even life advice. The views expressed in the podcast are not representative of hosts' employers views. We are acting independently of our respective professional roles.

On this episode of the Off the Charts Football Podcast, host Bryce Rossler is joined by Matty Brown of Angstrom Sports to preview the NFC West.Among the topics discussed:* The consequences of the Seahawks regime change from Pete Carroll to Mike McDonald * The impact of the 49ers potential trade of Brandon Aiyuk and the issues with their defensive line.* The Rams and the losses of both Aaron Donald and Raheem Morris * The potential of the Cardinals offense and their defensive deficiencies.Find our content at SportsInfoSolutions.com and follow us on Twitter at @football_SIS.

This is our first mediation called Healing Sun Mediation. Audiobooks and courses: https://emma-digallo-s-school.teachable.com/ YouTube Channel self-care: https://www.youtube.com/channel/UCFo4nESomKOXVrKDoST6GfQ YouTube Channel All about Business: https://www.youtube.com/channel/UC86s2ZCT-JvW4A5i3UfoaLACredit for the sound of the sun NASA's Goddard Space Flight CenterCredit picture of the Sun NASA's Solar Dynamics Observatory captured this image of a solar flare – as seen in the bright eruption on the lower left – at 6:57 UTC on May 27, 2024. The image shows a blend of 171 Angstrom and 304 Angstrom light, subsets of extreme ultraviolet light. Credit: NASA/SDO

Great villain, Great movie. --- Support this podcast: https://podcasters.spotify.com/pod/show/leroy-furious/support

One is Mostly Good, Whilst One is Great! This week on the Toonsday Animation Reviews, Brian and Darryl are talking about the most recent episodes of Invincible and X-Men ’97. Episode Index Intro: 0:07 Invincible: 3:16 X-Men ’97: 19:17 Invincible (Amazon Prime) Out of 5 Who Doesn’t Have Agency Now Ambers Darryl: 3.25/5 Brian: 3.55/5 Title: “I’m Not Going Anywhere” Directed by: Ian Abando Written by: Simon Racioppa Date Aired: March 28, 2024 Summary Mark and Amber attend a comic convention, but he leaves to help Rex. After Cecil puts the Immortal on temporary leave, Rudy returns as the Guardians’ leader. Donald discovers that he has died numerous times and that the original ordered the memories to be erased. Nonetheless, he later overcomes the trauma while dissuading Rick from committing suicide. While on a date, Mark is confronted by the Viltrumite Anissa who tries to remind him to have Earth join the Viltrumite Empire. When Mark abruptly leaves to save a cruise ship from a kaiju, Anissa joins him and effortlessly kills it, saving the passengers. Despite proving Earth’s weakness, Anissa fails to convince Mark to complete his mission and grievously beats him before ultimately sparing him and leaving to report back to Kregg. Amidst this, the Viltrumites confront a passing Allen, who feigns defeat and allows himself to be captured. After breaking up with Amber, Mark is called by Angstrom who has taken Debbie and Oliver hostage. X-Men ’97 (Disney+) Out of 5 Is The Inferno Upon Us Darryl: 4.3/5 Brian: 4.35/5 Title: “Fire Made Flesh” Directed by: Emi Yonemura Written by: Beau DeMayo and Charley Feldman Date Aired: March 27, 2024 Summary The X-Men take in the Jean look-alike, who Beast determines is the real Jean. Mister Sinister contacts the other Jean, revealing her to be a clone he created, before asserting control of her and turning her into the Goblin Queen. She kidnaps Nathan and hands him off to Sinister before subjecting the X-Men to horrific visions until the real Jean confronts her telepathically, during which the latter reminds her of their shared memories. Morph leads the X-Men to one of Sinister’s labs, where they find him infecting Nathan with a techno-organic virus under the belief that it will turn him into the ultimate mutant. Free of Sinister’s control, the clone turns on him, but Nathan is left gravely ill. The clone and Cyclops task Bishop with taking Nathan to the future in the hopes of finding a cure there. Afterward, the clone leaves the X-Men, taking the name Madelyne Pryor. Meanwhile, Storm meets with Forge who tells her he can restore her powers. Infamous Shirts for Naked Bodies… You’ll feel “shirty” when you buy our gear from the Flying Pork Apparel Co. Contact Us The Infamous Podcast can be found wherever podcasts are found on the Interwebs, feel free to subscribe and follow along on social media. And don't be shy about helping out the show with a 5-star review on Apple Podcasts to help us move up in the ratings. @infamouspodcast facebook/infamouspodcast instagram/infamouspodcast stitcher Apple Podcasts Spotify Google Play iHeart Radio contact@infamouspodcast.com Our theme music is ‘Skate Beat’ provided by Michael Henry, with additional music provided by Michael Henry. Find more at MeetMichaelHenry.com. The Infamous Podcast is hosted by Brian Tudor and Darryl Jasper, is recorded in Cincinnati, Ohio. The show is produced and edited by Brian Tudor. Subscribe today!

Welcome to BingetownTV's coverage of Amazon's Invincible Season 2 Episode 5-6. On this podcast, we discuss the Guardians vs The Sequids, The B Squad vs the Lizard League and all things Amber and Mark related. Cannot believe there are only two more episodes left this season but we are finally gearing up to face off against the big baddy of S2, Angstrom.   More BingetownTV Content! Check Out Our Podcast on Youtube! Check Out Our Youtube Entertainment Channel! Join the BingetownTV Community Discord (FREE) Follow us on Socials! ** Instagram- https://www.instagram.com/bingetowntv/ Twitter/X - https://twitter.com/bingetowntvpod TikTok- https://www.tiktok.com/@bingetowntv?_t=8gdE279ReTm&_r=1 Support the Pod! Patreon- **www.patreon.com/bingetowntv Learn more about your ad choices. Visit megaphone.fm/adchoices

Another week, another NVIDIA SUPER launch. But this is the last one, we promise. (We hope.) You probably already know it's barely any faster than the original, but it's $200 less (in the USA anyhow) so who cares, right??We talked about more stuff, too like why security is terrible and a cool game named "Judas".  Also, just check the time stamps below. Recorded January 31, 2024 using digital recording technology unheard of in the Middle Ages.Timestamps:00:00 Intro02:10 Food with Josh03:59 RTX 4080 SUPER review12:33 Josh's Soapbox (and further GPU rambles)18:05 AMD's 2023 results are in25:57 Microsoft Teams outage27:35 Edge is taking over Chrome (just a  "bug" so don't worry)30:38 Are process nodes reality, or marketing?37:34 Security Corner45:26 Gaming Quick Hits50:34 Fosi Audio ZA3 dual-mode amp review58:32 Picks of the Week1:06:29 Outro ★ Support this podcast on Patreon ★

Has Invincible hit it's stride yet? --- Support this podcast: https://podcasters.spotify.com/pod/show/allnew52/support

Season 6 | Episode 5 In this episode of Bell Curve we dive into the world of batch auctions with special guests Anna, co-founder of CowSwap, and Ludwig, Founder of Sorella Labs. The team digs into how Cowswap's innovative batch auctions function and how Sorella Labs' Angstrom project tackles LVR for sustainable liquidity. They unpack how app layer innovation and MEV-conscious design can mitigate value extraction. To close out they discusses whether price discovery will ever move from centralized to decentralized exchanges and what prerequisites are necessary for that to happen. Enjoy! - - Maverick Protocol is a DeFi infrastructure provider focused on increasing industry efficiency, powered by Maverick AMM. Maverick helps token projects, DAO treasuries, liquidity providers or anyone in DeFi shape their liquidity with efficiency and flexibility. In other words, Maverick makes your liquidity smarter.  Shape liquidity for your token today on Maverick at https://app.mav.xyz/bellcurve   - - Join us at DAS (Digital Asset Summit) in London this March! DAS is the #1 institutional conference in crypto, hosted by Blockworks. Use the link below to learn more, and use BELL20 to get 20% off your ticket! Sign up now because the price goes up every month. See you there! https://blockworks.co/event/digital-asset-summit-2024-london/home - - Timestamps: (0:00) Interview Start: Anna & Ludwig (4:47) What are Frequent Batch Auctions? (10:50) MEV by Passive LPs (15:42) Mechanism Design Avoiding MEV (21:20) DAS London Ad (22:29) Who are Solvers & their role in CoWSwap (29:40) How Angstrom Solves DEX MEV (33:06) CoW Hooks (38:18) Maverick Ad (39:33) Will Passive Liquidity Stay? (46:38) Why is Angstrom a Uniswap Hook? (52:07) Will Price Discovery Come Onchain? (58:47) Outro - - Follow Dan: https://twitter.com/danrobinson Follow Mike: https://twitter.com/MikeIppolito_ Follow Anna: https://twitter.com/AnnaMSGeorge Follow Ludwig: https://twitter.com/0xvanbeethoven Subscribe on YouTube: https://bit.ly/3R1D1D9 Subscribe on Apple: https://apple.co/3pQTfmD Subscribe on Spotify: https://spoti.fi/3cpKZXH - - Resources: https://twitter.com/Sorellalabs https://twitter.com/CoWSwap - - Disclaimer: Nothing said on Bell Curve is a recommendation to buy or sell securities or tokens. This podcast is for informational purposes only, and any views expressed by anyone on the show are solely our opinions, not financial advice. Mike, Jason, Michael, Vance and our guests may hold positions in the companies, funds, or projects discussed.

Invincible on Prime is as Uneven as Amber's character on Prime This week on the podcast, Brian and Darryl revisit the University of Michigan nonsense from the Big-10, talk about The Marvels' box office woes, and review Invincible Season 2 Episodes 1 & 2. Episode Index Intro: 0:07 Wolverines: 6:00 The Marvels: 18:07 Invincible: 31:52 News Bites University of Michigan board considers leaving Big Ten https://sports.yahoo.com/si-university-michigan-board-considers-234631406.html Box Office Bomb: ‘The Marvels' Opens to $47M in New Low for Marvel Studios https://www.hollywoodreporter.com/movies/movie-news/the-marvels-box-office-bombing-opening-1235644758/ Invincible (Amazon Prime) Season 2 Episode 1 Out of 5 How Many Angstroms Does it Take to End the Worlds Darryl: 3.85/5 Brian: 4/5 Title: "A Lesson For Your Next Life" Directed by: Sol Choi Written by: Simon Racioppa Aired: November 3, 2023 Summary: On a devastated alternate Earth where Mark sided with Nolan, scientist Angstrom Levy escapes through a mysterious portal. One month after Nolan's departure, Mark continues to struggle with his father's betrayal while performing his duties as Invincible. Cecil appoints the revived Immortal to succeed Rudy as the Guardians' leader and adds a new hero called Bulletproof to their ranks. The Maulers escape prison with help from their version of Angstrom who tasks them with building a device capable of transferring the memories of various alternate universe variants of himself to him so he can use their collective knowledge to advance Earth's technology and save other planets. Cecil sends Mark to stop the Maulers as they begin the process, forcing Angstrom to use his multiversal powers to summon variants of the Maulers, who nearly kill Mark against his wishes. Angstrom stops the transfer prematurely, killing all of the variants present and horrifically scarring his body. Driven mad by his variants' memories of their versions of Invincible and Omni-Man, Angstrom vows revenge on Mark and escapes. Episode 2 Fish Weddings Are Weirds Out of 5 Darryl: 3/5 Brian: 3.25/5 Title: "In About Six Hours I Lose My Virginity to a Fish" Directed by: Ian Abando Written by: Matt Lambert Aired: November 10, 2023 Summary: During his graduation, Mark defeats Doc Seismic and his Magmanites. In the summer, he continues his work as Invincible, but tension grows between him and Debbie when she realizes he is only doing it to avoid Nolan's legacy. She confronts Cecil about Mark working under him but is shocked to see Donald alive. After completing a damaged apartment in Chicago, Eve argues with her father, believing he is incapable of accepting she can help. The stowaway Martian sees what Martian Man became on Earth and joins the Guardians as the Shapesmith. After encountering and defeating Darkwing's son, Mark meets with Cecil, who explains he must appease the Atlanteans for Aquarus' death. In a trial by combat, Mark battles a kaiju and is injured when it produces a sound that damages his ears. Against Cecil's orders to abandoned them, he saves the Atlanteans when the kaiju attacks them. Eve is horrified to learn the apartment she rebuilt has collapsed, built over unstable ground, though no one was killed. Confronted with aspects of her life that remind her of Nolan, Debbie breaks down and is embraced by Mark. Infamous Shirts for Naked Bodies... You'll feel "shirty" when you buy our gear from the Flying Pork Apparel Co. Contact Us The Infamous Podcast can be found wherever podcasts are found on the Interwebs, feel free to subscribe and follow along on social media. And don't be shy about helping out the show with a 5-star review on Apple Podcasts to help us move up in the ratings. @infamouspodcast facebook/infamouspodcast instagram/infamouspodcast stitcher Apple Podcasts Spotify Google Play iHeart Radio contact@infamouspodcast.com Our theme music is 'Skate Beat' provided by Michael Henry, with additional music provided by Michael Henry. Find more at MeetMichaelHenry.com. The Infamous Podcast is hosted by Brian Tudor and Darryl Jasper, is recorded in Cincinnati, Ohio. The show is produced and edited by Brian Tudor. Subscribe today!

In celebration of Invincible season 2, I discuss the comic book history of Angstrom Levy! One of my favorite Invincible villains. _ Please leave a review and a five-star rating! Make sure to follow me on Instagram: ⁠⁠⁠⁠⁠⁠⁠https://instagram.com/samtalksnerdy?igshid=YmMyMTA2M2Y= ⁠⁠⁠⁠⁠⁠ Make sure to subscribe to the Sam Talks Nerdy Youtube Channel: ⁠https://www.youtube.com/channel/UCS7TEni_NkSD1Uxbpj2M-0A⁠ Leave a ⁠⁠⁠⁠⁠⁠voice message for me on the Anchor⁠⁠⁠⁠⁠⁠! Make sure to follow me on: ⁠⁠⁠⁠⁠ Spotify⁠⁠⁠⁠⁠⁠: ⁠⁠⁠⁠⁠⁠⁠⁠⁠https://open.spotify.com/show/3G7QLpUnH6PP61KH5xifip?si=kMghGs5XSJWF5HM0JwXUXQ⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠Apple Podcast: ⁠⁠⁠⁠⁠⁠⁠⁠⁠https://podcasts.apple.com/us/podcast/sam-talks-nerdy/id1523679299⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠Google Podcast:⁠⁠⁠⁠⁠⁠ ⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠https://podcasts.google.com/feed/aHR0cHM6Ly9hbmNob3IuZm0vcy8yYjAzMTY0OC9wb2RjYXN0L3Jzcw⁠⁠⁠

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Our new STA series! ---- Check Our Website: https://trek-time.com Join The Discord: https://bit.ly/trek-time Follow Us On Twitch: https://twitch.tv/TrekTime Subscribe To Our Podcast: https://anchor.fm/s/256197a0/podcast/rss Follow Us On Twitter: https://twitter.com/TrekTime_ ---- All LCARS adapted from the amazing work done by Adge Cutler over at http://lcars.org.uk/

- Entain acquires Angstrom Sports to strengthen US sports betting capabilities - Entain acquires Angstrom Sports to strengthen US sports betting capabilities - Betfred hit with £3.25m UKGC settlement for AML and responsibility failures - UK to require parental consent for under-18 loot box purchases Hang out with Jake Evans & Conor Mulheir with an occasional expert guest on our Weekly News live stream, every Thursday at 3PM CET across all our social media channels. We'll dive into the freshest iGaming news and explore the most captivating stories of the week. This is your chance to join the conversation, share your thoughts, and connect with a community of iGaming enthusiasts. Tune in to the iGaming NEXT Weekly News Roundup for a real-time, unfiltered take on the industry's hottest developments. Be cool, be curious, be in the know

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.12.10.519866v1?rss=1 Authors: Liu, S., Jiang, T., Bu, F., Zhao, J., Wang, G., Yang, G., Kong, J., Qie, Y., Wen, P., Fan, L., Li, N., Gao, N., Qiu, X. Abstract: Caspase-9 is the initiator caspase for the intrinsic apoptotic cell death pathway, and is critical to the activation of effector caspases during apoptosis, but how its levels and activities are maintained remains unclear. The gigantic Inhibitor of Apoptosis Protein (IAP) BIRC6/BRUCE/Apollon not only inhibits apoptosis, but also promotes ubiquitination of the key autophagic protein LC3 and inhibits autophagy. Here we show that BIRC6 forms an anti-parallel U-shaped dimer in a 3.6-Angstrom cryo-EM structure with multiple previously unannotated domains, including a ubiquitin-like domain, and discover that the mitochondria-derived pro-apoptotic factor Smac/DIABLO binds BIRC6 by interacting with one BIR domain, two carbohydrate-binding modules and two helices in the central cavity. Notably, Smac outcompetes the effector caspase 3 and the pro-apoptotic protease HtrA2, but not caspase 9, for binding BIRC6. BIRC6 strongly inhibits cellular activity of caspase 9, but weakly suppresses that of caspase 3. Meanwhile, BIRC6 binds LC3 through an LC3-interacting region, probably following dimer disruption of this BIRC6 region. Deficiency in LC3 ubiquitination promotes autophagy and autophagic degradation of BIRC6, and inhibits apoptosis. Moreover, induction of autophagy promotes autophagic degradation of both procaspase-9 and active caspase-9, but not of effector caspases. These results are important to understand how the balance between apoptosis and autophagy is regulated under pathophysiological conditions. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Before net zero, climate policy was all about contraction and convergence of emissions between rich and poor to achieve, in the words of the Rio Convention, “stabilization of greenhouse gas concentrations in the atmosphere” at a safe level. But scientists struggled to establish what that “safe” level was, making little progress in over a quarter of a century. And it was not because we were incompetent: for fundamental reasons in physics and probability theory, we were asking the wrong question.A lecture by Myles AllenThe transcript and downloadable versions of the lecture are available from the Gresham College website: https://www.gresham.ac.uk/watch-now/atmospheric-zeroGresham College has offered free public lectures for over 400 years, thanks to the generosity of our supporters. There are currently over 2,500 lectures free to access. We believe that everyone should have the opportunity to learn from some of the greatest minds. To support Gresham's mission, please consider making a donation: https://gresham.ac.uk/support/Website:  https://gresham.ac.ukTwitter:  https://twitter.com/greshamcollegeFacebook: https://facebook.com/greshamcollegeInstagram: https://instagram.com/greshamcollege

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.10.19.512855v1?rss=1 Authors: Duan, J., Liu, H., Ji, Y., Yuan, Q., Li, X., Wu, K., Gao, T., Zhu, S., Jiang, Y., Yin, W., Xu, H. E. Abstract: Phosphorylation of G protein-coupled receptors (GPCR) by GPCR kinases (GRKs) desensitizes G protein signaling and promotes arrestin signaling, which is also modulated by biased ligands. Molecular assembly of GRKs to GPCRs and the basis of GRK-mediated biased signaling remain largely unknown due to the weak GPCR-GRK interactions. Here we report the complex structure of neurotensin receptor 1 (NTSR1) bound to GRK2, Gaq, and an arrestin-biased ligand, SBI-553, at a resolution of 2.92 Angstrom. The high-quality density map reveals the clear arrangement of the intact GRK2 with the receptor, with the N-terminal helix of GRK2 docking into the open cytoplasmic pocket formed by the outward movement of the receptor TM6, analogous of the binding of G protein to the receptor. Strikingly, the arrestin-biased ligand is found at the interface between GRK2 and NTSR1 to enhance GRK2 binding. The binding mode of the biased ligand is compatible with arrestin binding but is clashed with the binding of a G protein, thus provide an unambiguous mechanism for its arrestin-biased signaling capability. Together, our structure provides a solid model for understanding the details of GPCR-GRK interactions and biased signaling. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

This week we discuss all the products introduced at Apple's Far Out event on Sept 7, 2022. We fact check Compose Custom Layouts in SwiftUI, the checkmark in the Developer app, Friday Night Baseball in Canada, and Universal Control. We follow up on Apple's Self Repair now includes M1, and Xcode Cloud availability for trial. We discuss the past and future of the 360iDev conference. We discuss the Apple Watch Series 8, Apple Watch SE, Apple Watch Ultra, Air Pods Pro 2nd gen, the iPhone 14, and the iPhone 14 Pro. We also discus What's New in Swift 5.7. Picks: WWDC22 SwiftUI Lounge archived, Cmd Opt R, Cmd Shift J, Swift Version, SwiftUI Essential Training, and Design the Next iPhone.

Shocks in the outflow of the RS Oph 2021 eruption observed with X-ray gratings by Marina Orio et al. on Tuesday 06 September The 2021 outburst of the symbiotic recurrent nova RS Oph was observed with the Chandra High Energy Transmission Gratings (HETG) on day 18 after optical maximum and with XMM-Newton and its Reflection Grating Spectrographs (RGS) on day 21, before the supersoft X-ray source emerged and when the emission was due to shocked ejecta. The absorbed flux in the HETG 1.3-31 Angstrom range was 2.6 x 10(-10) erg/cm(-2)/s, three orders of magnitude lower than the gamma-ray flux measured on the same date. The spectra are well fitted with two components of thermal plasma in collisional ionization equilibrium, one at a temperature ~0.75 keV, and the other at temperature in the 2.5-3.4 keV range. With the RGS we measured an average flux 1.53 x 10(-10) erg/cm(-2)/s in the 5-35 Angstrom range, but the flux in the continuum and especially in the lines in the 23-35 Angstrom range decreased during the 50 ks RGS exposure by almost 10%, indicating short term variability on hours' time scale. The RGS spectrum can be fitted with three thermal components, respectively at plasma temperature between 70 and 150 eV, 0.64 keV and 2.4 keV. The post-maximum epochs of the exposures fall between those of two grating spectra observed in the 2006 eruption on days 14 and 26: they are consistent with a similar spectral evolution, but in 2021 cooling seems to have been more rapid. Iron is depleted in the ejecta with respect to solar values, while nitrogen is enhanced. arXiv: http://arxiv.org/abs/http://arxiv.org/abs/2209.02123v1

When you look at a leaf, what color do you see? While a leaf may appear green, it is not necessarily producing green light. The leaf absorbs wavelengths of red light, and reflects the green light that we see. Professor Alexander Wei's research group synthesizes molecules and nanomaterials, and studies how these materials interact with light. Wei discusses luminescence, fluorescence, phosphorescence, and where we can observe these light-related properties in our everyday life. Wei's group is currently focused on designing and developing new materials that produce blue light. There is a current need for blue-light producing materials that can be used with an exciting new technology related to the next generation of flat panel television displays: Organic Light-Emitting Diodes (OLEDs).     Special thanks for support from NSF grant CHE-2204206

In this episode, Senior Pastor Damein Schitter asks longtime Executive Director Aaron Angstrom about his "holy disruption" and how it led to his upcoming transition from staff at NewCity to working with Auxilio. They reminisce about Aaron's time at NewCity and look forward in hope to the road that lies ahead for Aaron and the Angstroms. 

The Doctor has a dark past, sure - but he's never been ripped apart and turned into a robot. Ellie Littlechild presents 10 Doctor Who Side Characters With Tragic Backstories... See acast.com/privacy for privacy and opt-out information.

An interview with artist and gallerist David Quadrini, on the occasion of the exhibition "An Artists' Homage to the Dynamic Influence of Rick Brettell," curated by Greg Metz at SP/N Gallery, UT Dallas, Sept. 10 to Oct. 9, 2021. https://calendar.utdallas.edu/event/art_exhibition_brettell_an_artistshomageto_the_dynamic_influence_of_rick_brettell http://athenaeumreview.org/podcasts

Angstrom is the next processor size, why does Google want to know my birthdate? HDR projectors with Scott Wilkinson, will a new TV work with my current setup? Can I still use my old Kindle if they turn off cellular access? Travel updates with Johnny Jet, how to know how long a Chromebook will be updated, why are there streaks on my laptop screen? Resetting your Apple ID, accessibility on iDrive, calibrating a computer monitor, a gadget to improve Wi-Fi with the GizWiz, and more of your calls! Host: Leo Laporte Guests: Scott Wilkinson, Johnny Jet, and Dick DeBartolo Download or subscribe to this show at https://twit.tv/shows/the-tech-guy. Get episodes ad-free with Club TWiT at https://twit.tv/clubtwit For detailed show notes, visit techguylabs.com.

Angstrom is the next processor size, why does Google want to know my birthdate? HDR projectors with Scott Wilkinson, will a new TV work with my current setup? Can I still use my old Kindle if they turn off cellular access? Travel updates with Johnny Jet, how to know how long a Chromebook will be updated, why are there streaks on my laptop screen? Resetting your Apple ID, accessibility on iDrive, calibrating a computer monitor, a gadget to improve Wi-Fi with the GizWiz, and more of your calls! Host: Leo Laporte Guests: Scott Wilkinson, Johnny Jet, and Dick DeBartolo Download or subscribe to this show at https://twit.tv/shows/the-tech-guy. Get episodes ad-free with Club TWiT at https://twit.tv/clubtwit For detailed show notes, visit techguylabs.com.

Angstrom is the next processor size, why does Google want to know my birthdate? HDR projectors with Scott Wilkinson, will a new TV work with my current setup? Can I still use my old Kindle if they turn off cellular access? Travel updates with Johnny Jet, how to know how long a Chromebook will be updated, why are there streaks on my laptop screen? Resetting your Apple ID, accessibility on iDrive, calibrating a computer monitor, a gadget to improve Wi-Fi with the GizWiz, and more of your calls! Host: Leo Laporte Guests: Scott Wilkinson, Johnny Jet, and Dick DeBartolo Download or subscribe to this show at https://twit.tv/shows/the-tech-guy. Get episodes ad-free with Club TWiT at https://twit.tv/clubtwit For detailed show notes, visit techguylabs.com.

Angstrom is the next processor size, why does Google want to know my birthdate? HDR projectors with Scott Wilkinson, will a new TV work with my current setup? Can I still use my old Kindle if they turn off cellular access? Travel updates with Johnny Jet, how to know how long a Chromebook will be updated, why are there streaks on my laptop screen? Resetting your Apple ID, accessibility on iDrive, calibrating a computer monitor, a gadget to improve Wi-Fi with the GizWiz, and more of your calls! Host: Leo Laporte Guests: Scott Wilkinson, Johnny Jet, and Dick DeBartolo Download or subscribe to this show at https://twit.tv/shows/the-tech-guy. Get episodes ad-free with Club TWiT at https://twit.tv/clubtwit For detailed show notes, visit techguylabs.com.

Angstrom is the next processor size, why does Google want to know my birthdate? HDR projectors with Scott Wilkinson, will a new TV work with my current setup? Can I still use my old Kindle if they turn off cellular access? Travel updates with Johnny Jet, how to know how long a Chromebook will be updated, why are there streaks on my laptop screen? Resetting your Apple ID, accessibility on iDrive, calibrating a computer monitor, a gadget to improve Wi-Fi with the GizWiz, and more of your calls! Host: Leo Laporte Guests: Scott Wilkinson, Johnny Jet, and Dick DeBartolo Download or subscribe to this show at https://twit.tv/shows/the-tech-guy. Get episodes ad-free with Club TWiT at https://twit.tv/clubtwit For detailed show notes, visit techguylabs.com.

Angstrom is the next processor size, why does Google want to know my birthdate? HDR projectors with Scott Wilkinson, will a new TV work with my current setup? Can I still use my old Kindle if they turn off cellular access? Travel updates with Johnny Jet, how to know how long a Chromebook will be updated, why are there streaks on my laptop screen? Resetting your Apple ID, accessibility on iDrive, calibrating a computer monitor, a gadget to improve Wi-Fi with the GizWiz, and more of your calls! Host: Leo Laporte Guests: Scott Wilkinson, Johnny Jet, and Dick DeBartolo Download or subscribe to this show at https://twit.tv/shows/the-tech-guy. Get episodes ad-free with Club TWiT at https://twit.tv/clubtwit For detailed show notes, visit techguylabs.com.

Angstrom is the next processor size, why does Google want to know my birthdate? HDR projectors with Scott Wilkinson, will a new TV work with my current setup? Can I still use my old Kindle if they turn off cellular access? Travel updates with Johnny Jet, how to know how long a Chromebook will be updated, why are there streaks on my laptop screen? Resetting your Apple ID, accessibility on iDrive, calibrating a computer monitor, a gadget to improve Wi-Fi with the GizWiz, and more of your calls! Host: Leo Laporte Guests: Scott Wilkinson, Johnny Jet, and Dick DeBartolo Download or subscribe to this show at https://twit.tv/shows/the-tech-guy. Get episodes ad-free with Club TWiT at https://twit.tv/clubtwit For detailed show notes, visit techguylabs.com.

Angstrom is the next processor size, why does Google want to know my birthdate? HDR projectors with Scott Wilkinson, will a new TV work with my current setup? Can I still use my old Kindle if they turn off cellular access? Travel updates with Johnny Jet, how to know how long a Chromebook will be updated, why are there streaks on my laptop screen? Resetting your Apple ID, accessibility on iDrive, calibrating a computer monitor, a gadget to improve Wi-Fi with the GizWiz, and more of your calls! Host: Leo Laporte Guests: Scott Wilkinson, Johnny Jet, and Dick DeBartolo Download or subscribe to this show at https://twit.tv/shows/the-tech-guy. Get episodes ad-free with Club TWiT at https://twit.tv/clubtwit For detailed show notes, visit techguylabs.com.

Angstrom is the next processor size, why does Google want to know my birthdate? HDR projectors with Scott Wilkinson, will a new TV work with my current setup? Can I still use my old Kindle if they turn off cellular access? Travel updates with Johnny Jet, how to know how long a Chromebook will be updated, why are there streaks on my laptop screen? Resetting your Apple ID, accessibility on iDrive, calibrating a computer monitor, a gadget to improve Wi-Fi with the GizWiz, and more of your calls! Host: Leo Laporte Guests: Scott Wilkinson, Johnny Jet, and Dick DeBartolo Download or subscribe to this show at https://twit.tv/shows/the-tech-guy. Get episodes ad-free with Club TWiT at https://twit.tv/clubtwit For detailed show notes, visit techguylabs.com.

This week on the Champion Challenge our panel will answer the question, which independent comic book villain is the smartest? Our contestants are Bendy, Angstrom Levy, Light Yagami, and Mammon.   Our current panelists are DC Dark, Deep Cuts, Mister KAM, and Sugah Shade.   The Champion Challenge was produced by People Like Us Studios LLC (PLUS LLC), People.Like.Us.Studios@gmail.com, and our panelists can be contacted at champion.challenge.mailbox@gmail.com   Or you can tweet to us on our Twitter page, @WNYChampions   Please consider subscribing to us through our Patreon page, Champion Challenge.   Our theme tune was composed and performed by Derrick Streibig.   Our favorite charity is the Superhero Alliance of Western New York. You can find them on Facebook at  Superhero Alliance-SAWNY, on Twitter at superheroWNY, on Instagram at SuperheroAllianceWNY, or on their website, www.sawny.org.   Superhero Storytime, a video project by the Superhero Alliance, features costume characters reading stories intended to be view by parents with their children at https://tinyurl.com/superhero-storytime   If you want to send a loved one a Hero-gram, use this link: https://forms.gle/j7nD6JbS19x5iW2S9   For appearance requests, use this link: http://goo.gl/forms/iQmt8FI3Zo   To donate to SAWNY via Amazon Smile: https://smile.amazon.com/ch/82-3176986  

West Coast Grocery has been cranking out some serious beer love to their neighborhood, and we've taken notice.  Just stroll up to their special beer window the past year and you are greeted warmly with a special curated selection.  We are recording once again from their secret Bodega Barrel Room where all the best beers are hiding and waiting for your glass.  Charlie Hyde IV brings brewers Christian Angstrom and Brian Detweiler-Bedell to nerd out with us on this episode of Brew Happy!

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.11.11.378083v1?rss=1 Authors: Ahmed, S. R., Banik, A., Anni, S. M., Chowdhury, M. M. H. Abstract: The ZIKA virus has caused a heavy concern everywhere the globe because of its high infectivity and mortality rate. Still, there's no specific drug or preventive medication to treat ZIKA infection despite comprehensive analysis by the researchers. This study was designed to demonstrate the efficacy of some plant derived bioactive compounds against ZIKV by using both structure and ligand based virtual screening methods. A number of 35 plant metabolites were screened against ZIKA NS2B-NS3 protease (5LC0), Envelop protein (5JHM), Capsid protein (5YGH) and NS5 RNA-dependent RNA polymerase protein (5U04) employing molecular docking approach. Results showed that there have been four metabolites, i.e. Chicoric acid, Luteone, Reserpine and Rosmarinic acid provide highest binding affinity to targeted ZIKV proteins. Crucial binding sites and drug surface hotspots are unraveled for every targeted viral protein. The ADME study showed that neither of the candidate compounds had side effects that would reduce their drug-like properties. As compared, the toxicity pattern analysis has unmasked the non-toxic essence of top drug candidates. The RMSD values of ligand-macromolecule complexes were 2 Angstrom apart from Envelop protein- Chicoric Acid, although the RMSF values showed normal atomic fluctuations within the molecular dynamics analysis, with the exception of Envelop protein- Chicoric Acid. The expected majority of the target class the highest drug candidates is enzyme classes (e.g. protease, hydrolase, phosphatase). In addition, the drug similarity prediction revealed several structural analogs from drugbank such as Isoformononetin (DB04202), Deserpidine (DB01089) and Rescinnamine (DB01180) etc. and these analogs could even be an option for the treatment of ZIKV infections. The study can pave the way for the creation of effective ZIKV medications and preventive measures. We highly recommend further in vivo trials for the experimental validation of our findings. Copy rights belong to original authors. Visit the link for more info

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.10.21.349431v1?rss=1 Authors: Gardiner, A. T., Naydenova, K., Hartmann, P. C., Nguyen-Phan, T. C., Russo, C. J., Sader, K., Hunter, C. N., Cogdell, R. J., Qian, P. Abstract: We report the 2.4 Angstrom resolution structure of the light harvesting 2 complex (LH2) from Marichromatium (Mch.) purpuratum determined by electron cryo-microscopy. The structure contains a heptameric ring that is unique among all known LH2 structures, explaining the unusual spectroscopic properties of this bacterial antenna complex. Two sets of distinct carotenoids are identified in the structure, and a network of energy transfer pathways from the carotenoids to bacteriochlorophyll a molecules is shown. The geometry imposed by the heptameric ring controls the resonant coupling of the long wavelength energy absorption band. Together, these details reveal key aspects of the assembly and oligomeric form of purple bacterial LH2 complexes that were previously inaccessible by any technique. Copy rights belong to original authors. Visit the link for more info

This week we follow up on MTJC 2018 T-Shirts and the origins of Apple's Command Key. We also follow up on the Apple Store founders, Apple's GDPR profile downloads, Apple Watch usage and Apple's self driving cars. We discuss the Home Pod sales numbers, erroneous new Siri features, and a sophisticate worm virus and one of the first Internet hackers. We also chat about Apple's own podcasts and their use of original illustrations on the App Store. Picks: A handy Xcode keyboard shortcut to the Assistant Editor and App: the Human Story, Developing UIViews in Xcode Playgrounds and 1Password 7. Photo: Tim Mitra Originally broadcast: May 26th, 2018

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.09.21.306357v1?rss=1 Authors: Ma, J., Su, D., Huang, X., Liang, Y., Ma, Y., Liang, P., Zheng, S. Abstract: Less than a year after its emergence, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected over 22 million people worldwide with a death toll approaching 1 million. Vaccination remains the best hope to ultimately put this pandemic to an end. Here, using Trimer-Tag technology, we produced both wild-type (WT) and furin site mutant (MT) S-Trimers for COVID-19 vaccine studies. Cryo-EM structures of the WT and MT S-Trimers, determined at 3.2 Angstrom and 2.6 Angstrom respectively, revealed that both antigens adopt a tightly closed conformation and their structures are essentially identical to that of the previously solved full-length WT S protein in detergent. These results validate Trimer-Tag as a platform technology in production of metastable WT S-Trimer as a candidate for COVID-19 subunit vaccine. Copy rights belong to original authors. Visit the link for more info

We fact check 3.5inch floppy sizes. Nvidia buying ARM for $40B. App Store Review Guideline updates now available. Apple Insider Confirms New iPhone 12, iPhone 12 Pro Releases. Apple Is About To Leave Your MacBook Air Behind. The State of SwiftUI. We cover the 9/15 Apple Event. Apple developers are scrambling over accelerated iOS 14 release. Picks: iOS 14 widgets you can try today.Core Data in SwiftUI.

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.09.16.299644v1?rss=1 Authors: Du, Y., An, W., Ye, K. Abstract: Previously, we determined a cryo-EM structure of Saccharomyces cerevisiae 90S preribosome obtained after depletion of the RNA helicase Mtr4 at 4.5 Angstrom resolution (Sun et al., 2017). The 90S preribosome is an early assembly intermediate of small ribosomal subunit. Here, the structure was improved to 3.4 Angstrom resolution and reveals many previously unresolved structures and interactions, in particular around the central domain of 18S rRNA. The central domain adopts a closed conformation in our structure, in contrast to an open conformation in another high-resolution structure of S. cerevisiae 90S. The new model of 90S would serve as a better reference for investigation of the assembly mechanism of small ribosomal subunit. Copy rights belong to original authors. Visit the link for more info

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.09.07.286831v1?rss=1 Authors: Cheng, R. C., Krishnamoorti, A., Berka, V., Durham, R. J., Jayaraman, V., Maduke, M. Abstract: CLC transporters catalyze the exchange of chloride ions for protons across cellular membranes. As secondary active transporters, CLCs must alternately allow ion permeation to the extracellular and intracellular sides of the membrane, adopting outward-facing and inward-facing conformational states. Here, we use single-molecule Forster resonance energy transfer (smFRET) to monitor the conformational state of CLC-ec1, an E. coli homolog for which high-resolution structures of occluded and outward-facing states are known. Since each subunit within the CLC homodimer contains its own transport pathways for chloride and protons, we developed a labeling strategy to follow conformational change within a subunit, without crosstalk from the second subunit of the dimer. Using this strategy, we evaluated smFRET efficiencies for labels positioned on the extracellular side of the protein, to monitor the status of the outer permeation pathway. When [H+] is increased to enrich the outward-facing state, the smFRET efficiencies for this pair decrease. In a triple-mutant CLC-ec1 that mimics the protonated state of the protein and is known to favor the outward-facing conformation, the lower smFRET efficiency is observed at both low and high [H+]. These results confirm that the smFRET assay is following the transition to the outward-facing state and demonstrate the feasibility of using smFRET to monitor the relatively small (~1 Angstrom) motions involved in CLC transporter conformational change. Using the smFRET assay, we show that the conformation of the partner subunit does not influence the conformation of the subunit being monitored by smFRET, thus providing evidence for the independence of the two subunits in the transport process. Copy rights belong to original authors. Visit the link for more info

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.09.06.285239v1?rss=1 Authors: Park, H., Zhou, G., Baek, M., Baker, D., DiMaio, F. Abstract: Accurate and rapid calculation of protein-small molecule interaction energies is critical for computational drug discovery. Because of the large chemical space spanned by drug-like molecules, classical force fields contain thousands of parameters describing atom-pair distance and torsional preferences; each parameter is typically optimized independently on simple representative molecules. Here we describe a new approach in which small-molecule force field parameters are jointly optimized guided by the rich source of information contained within thousands of available small molecule crystal structures. We optimize parameters by requiring that the experimentally determined molecular lattice arrangements have lower energy than all alternative lattice arrangements. Thousands of independent crystal lattice-prediction simulations were run on each of 1,386 small molecule crystal structures, and energy function parameters of an implicit solvent energy model were optimized so native crystal lattice arrangements had lowest energy. The resulting energy model was implemented in Rosetta, together with a rapid genetic algorithm docking method employing grid based scoring and receptor flexibility. The success rate of bound structure recapitulation in cross-docking on 1,112 complexes was improved by more than 10% over previously published methods, with solutions within

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.08.27.270637v1?rss=1 Authors: Flower, T. G., Buffalo, C. Z., Hooy, R. M., Allaire, M., Ren, X., Hurley, J. H. Abstract: The molecular basis for the severity and rapid spread of the COVID-19 disease caused by SARS-CoV-2 is largely unknown. ORF8 is a rapidly evolving accessory protein that has been proposed to interfere with immune responses. The crystal structure of SARS-CoV-2 ORF8 was determined at 2.04 Angstrom resolution by x-ray crystallography. The structure reveals a ~60 residue core similar to SARS-CoV ORF7a with the addition of two dimerization interfaces unique to SARS-CoV-2 ORF8. A covalent disulfide-linked dimer is formed through an N-terminal sequence specific to SARS-CoV-2, while a separate non-covalent interface is formed by another SARS-CoV-2-specific sequence, 73YIDI76. Together the presence of these interfaces shows how SARS-CoV-2 ORF8 can form unique large-scale assemblies not possible for SARS-CoV, potentially mediating unique immune suppression and evasion activities. Copy rights belong to original authors. Visit the link for more info

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.08.22.262675v1?rss=1 Authors: Wang, X., Alnabati, E., Aderinwale, T. W., Maddhuri Venkata Subramaniya, S. R., Terashi, G., Kihara, D. Abstract: An increasing number of density maps of macromolecular structures, including proteins and protein and DNA/RNA complexes, have been determined by cryo-electron microscopy (cryo-EM). Although lately maps at a near-atomic resolution are routinely reported, there are still substantial fractions of maps determined at intermediate or low resolutions, where extracting structure information is not trivial. Here, we report a new computational method, Emap2sec+, which identifies DNA or RNA as well as the secondary structures of proteins in cryo-EM maps of 5 to 10 Angstrom resolution. Emap2sec+ employs the deep Residual convolutional neural network. Emap2sec+ assigns structural labels with associated probabilities at each voxel in a cryo-EM map, which will help structure modeling in an EM map. Emap2sec+ showed stable and high assignment accuracy for nucleotides in low resolution maps and improved performance for protein secondary structure assignments than its earlier version when tested on simulated and experimental maps. Copy rights belong to original authors. Visit the link for more info

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.08.05.238287v1?rss=1 Authors: Sporny, M., Guez-Haddad, J., Khazma, T., Yaron, A., Dessau, M., Mim, C., Isupov, M. N., Zalk, R., Hons, M., Opatowsky, Y. Abstract: SARM1 is a central executor of axonal degeneration (1). Mechanistically, SARM1 contains NADase activity, which, in response to nerve injury, depletes the key cellular metabolite, NAD+ (2-5). Interestingly, SARM1 knockout mouse models do not present any apparent physiological impairment. Yet, the lack of SARM1 protects against various neuropathies (6, 7), thereby highlighting SARM1 as a likely safe and effective drug target (8). However, the absence of a SARM1 structure, in its active or inhibited form, makes it impossible to understand the molecular basis of SARM1 inhibition, and its activation under stress conditions. In this study we present two cryo-EM maps of SARM1 (at 2.6 and 2.9 Angstrom resolution). We show that the inhibited SARM1 homo-octamer assumes a packed conformation with well-ordered inner and peripheral rings. Here the catalytic TIR domains are held apart from each other and are unable to form dimers, which is a prerequisite for NADase activity. More importantly, after screening several cellular metabolites we discovered that the inactive conformation is stabilized by the binding of SARM1 own substrate: NAD+. The NAD+ inhibitory allosteric site is located away from the NAD+ catalytic site of the TIR domain. Site-directed mutagenesis of the allosteric site leads to constitutive active SARM1. Based on our data we propose that a reduction of cellular NAD+ concentrations (an early indication of disease-associated and age-related neurodegeneration (9)) disassemble SARM1 peripheral ring, which allows NADase activity. This leads to an energetic catastrophe and eventually cell death. The discovery of the allosteric inhibitory site opens the door for the development of effective drugs that will prevent SARM1 activation, rather than compete for binding to the NADase catalytic site. Copy rights belong to original authors. Visit the link for more info

Hey folks, as you might heard the 2020 edition of THIS IS SUMMER will be the very last after a 10-year-stretch. Time to look back. Here's the 2012 edition. Lots of timeless tunes, which really don't seem to be that old. Here's the original press release with playlist: It's again the season of the year, the season to spend your holidays, to enjoy the sun and to have some fun. To spend time on the beach, at the poolside or simply relax. In order to this feeling THIS IS SUMMER is a suggestion for your summer soundtrack in 2012. Seventynine minutes of enjoyable clubmusic with that decent flavour between sunmilk, BBQ and some refreshing drinks in the sun.Enjoy this summer!THIS IS SUMMER 2012 - mixed & compilied by Bek01. Scuba - Tulips02. Andrew Bayer - You03. Angstrom & Aalberg - Gorilla04. Guy Gerber - The Mirror Game05. Solomun & DJ Phono - Ice Cream & Bonus Miles06. Florence & The Machine - What Water Gave Me (DhARMA Edit)07. Maceo Plex - Frisky08. Blond:ish - Lonely Days09. DJ T. feat. Cari Golden - City Life (Maceo Plex Remix)10. Humate - Love Stimulation (Vincenzo Remix)11. Joe Goddard feat. Valentina - Gabriel12. Worthy - Shy Look13. Electric Rescue & Timid Boy - All Access14. Fusion F & Come T - Jumpin (Pete McCarthey Remix)15. Martin Roth - Beatiful Life

Hey folks, as you might heard the 2020 edition of THIS IS SUMMER will be the very last after a 10-year-stretch. Time to look back. Here's the 2012 edition. Lots of timeless tunes, which really don't seem to be that old. Here's the original press release with playlist: It's again the season of the year, the season to spend your holidays, to enjoy the sun and to have some fun. To spend time on the beach, at the poolside or simply relax. In order to this feeling THIS IS SUMMER is a suggestion for your summer soundtrack in 2012. Seventynine minutes of enjoyable clubmusic with that decent flavour between sunmilk, BBQ and some refreshing drinks in the sun.Enjoy this summer!THIS IS SUMMER 2012 - mixed & compilied by Bek01. Scuba - Tulips02. Andrew Bayer - You03. Angstrom & Aalberg - Gorilla04. Guy Gerber - The Mirror Game05. Solomun & DJ Phono - Ice Cream & Bonus Miles06. Florence & The Machine - What Water Gave Me (DhARMA Edit)07. Maceo Plex - Frisky08. Blond:ish - Lonely Days09. DJ T. feat. Cari Golden - City Life (Maceo Plex Remix)10. Humate - Love Stimulation (Vincenzo Remix)11. Joe Goddard feat. Valentina - Gabriel12. Worthy - Shy Look13. Electric Rescue & Timid Boy - All Access14. Fusion F & Come T - Jumpin (Pete McCarthey Remix)15. Martin Roth - Beatiful Life

Products I've experimented with: Basic Care Nicotine Polacrilex Gum, 2 mg (nicotine), Original Flavor-https://amzn.to/2VQA2ln Pixotine Toothpicks (no additives)- https://pixotine.com/collections/nicotine-toothpicks ---------------------------------------------- Dr. Jack Kruse on nicotine 02.2.2016 (https://www.facebook.com/drjackkruse/posts/1150518161679203): Nicotine has dramatic effect on cytochrome 1 tunneling of electrons: What is that effect? It lowers the % heteroplasmy in mitochondria. Why? It pulses superoxide while shortening the respiratory complex path to stimulate mitophagy to get rid of shitty mitochondria using programs built into to it. If the mitochondria is really bad..........and nicotine won't work you might consider adding methylene blue and a large dash of sunlight to the RPE. FYI: This is a biohack from something I've written. Random thought of the week that should stun you: Half the bestselling drugs in the US target the product of a circadian gene yet pharma ignores chronobiology...........share it with your fellow MD's, family, friends and your patients. For example take the best selling drugs, the statins, do they target circadian cycles? Yep. How? They block the Q cycle moving electrons from cytochrome 1 to 3 to increase the distance electrons can tunnel. Every increase in one Angstroms slows tunneling speeds by a factor of ten. As tunneling speeds slow what occurs? Inflammation and swelling. What is inflammation at its fundamental level? It is the excess of protons and/or loss of electrons at your surfaces. The surfaces being the eye, gut, and skin. pH is a function of proton concentration; low pH = high proton concentration = inflammation = lower EZ in water. Water is a chromophore for red light in the solar spectrum. Once the EZ is formed by proteins filled with electrons touching water, the EZ grows massively when 270 nm UV light hits a surface. If you cannot build an EZ what kind of life do you get? Optimal or suboptimal? Do you think a device designed to deliver purple and red light using surface cooling might have an effect on performance since it acts on this fundamental mechanism? I bet many Quantlet beta testers are already writing down bio-hacks as they read this. The loss of an EZ around the mitochondria for any reason increases the distance between respiratory proteins at the atomic level measured by Angstroms too. DO you see how the link of statins and a loss of EZ are similar? Key take home repeatable point: for every increase of 1 Angstrom, the rate of quantum tunneling of electrons drops ten fold. Do you think that kind of redox drop has a small effect or no effect on bio-energenics in a cell? Or might this be exactly how heteroplasmy develops? Is this why statins cause cognitive delay and metabolic syndrome in tissues with high mitochondrial density? Statins are well known to increase the distance electrons must travel via tunneling. Tiny shifts in your thinking, and even smaller changes in your energy status in mitochondria can lead to massive alterations of your results and the diseases you get. This is why people get sick today biophysically. People need to know this data. They also need to know that supplementing ubiquinol is highly beneficial for "statin patients only" because it shortens the distance between the same proteins to lower the energy barrier for quantum tunneling of electrons. Nicotine, MB, and red light all shortens the respiratory chain............because they all do some interesting things to the EZ around the mitochondria called the MINOS. Time 8 has massive implications...............http://1.bp.blogspot.com/…/s…/mitofamilyinheritanceimage.gif

This episode of Radio Hate is brought to you proudly by TerrorMax Extended Release tablets. Thanks to Dr. Troubadour’s hard work, your dying breath could be a chilling gasp of terror! In other news, a horrific fire destroyed the Law Offices of Tobasco, Biasco, Basko and Basco on Saturday, leaving the Internet confused and without […]

When an artificial intelligence chip falls into Dr. Troubadour’s hands, he becomes its slave on tonight’s episode of Radio HATE, by the Internet Chronicle. This program is brought to you proudly by Lebal Drocer, Inc. who carpets the lands, coast to coast, with chemical spray from 747s.

In this episode we review the Thirteenth Doctor story The Ghost Monument. In our review, we look at the developing relationships between the Doctor and her friends. Do we like what we’re seeing in the new Tardis team? What did we think of Angstrom and Epzo, particularly how Epzo contrasted with the Doctor? Are we happy with the new Tardis? We love feedback! Contact us in any of the ways you see below: Email: thewebofqueer@gmail.com Twitter: @thewebofqueer Tumblr: http://thewebofqueer.tumblr.com/ Facebook: https://www.facebook.com/groups/1429590183988830/ Libsyn: http://thewebofqueer.libsyn.com/ Opening and closing music: Doctor Who In Dub 2010 by Smerins Anti-Social Club http://www.smerins.com/

"Still reeling from their first encounter, can the Doctor and her new friends stay alive long enough, in a hostile alien environment, to solve the mystery of Desolation? And just who are Angstrom and Epzo?"Stay subscribed for our coverage of Doctor Who series 11 every week as we discuss the new episodes.Please subscribe, share and review.Find us on twitter with#WatchWorld@JohnnyBGoodInLa@Christian_Humes See acast.com/privacy for privacy and opt-out information.

The second epzode of Who Cares naturally covered the second episode of Doctor Who’s 11th series; THE GHOST MONUMENT.Just who are Angstrom and Epzo? The question had plagued our minds, a nonstop source of confusion and debate. Would Neo’s #teamepzo… Continue reading →

Episode Two - ‘The Ghost Monument’Still reeling from their first encounter, can the Doctor and her new friends stay alive long enough, in a hostile alien environment, to solve the mystery of Desolation? And just who are Angstrom and Epzo?Hosts:Dylan Blight: https://twitter.com/vivaladilAshley Hobley: https://twitter.com/ashleyhobleyExplosion Network - https://www.twitter.com/explosionpodAvailable on Youtube:http://www.youtube.com/explosionnetworkAvailable as on podcasting services including:Apple Podcasts https://itunes.apple.com/au/podcast/fish-fingers-and-custard-doctor-who-aftershow/id1437401936?mt=2Spotify - https://open.spotify.com/show/2u4yi0xqiHLSlYDM41pwRr?si=94hlIJrLSHGC285_Sy0WrAAll Episodes:https://explosionnetwork.com/fish-fingers-and-custard-doctor-who-aftershow-hub/Join our Discord:https://explosionnetwork.com/discord

AKA The Planet of Death Rob and Dave talk off-the-cuff and unstructured on the second Doctor Who Series 11 episode, The Ghost Monument. What did they make of it? [Still reeling from their first encounter, can the Doctor and her new friends stay alive long enough, in a hostile alien environment, to solve the mystery of Desolation? And just who are Angstrom and Epzo?] Contact us anytime at hello@theDWshow.net

The Internet plays an essential role in our modern society and yet the way the Internet will be governed is still unclear. In anticipation of an impending Federal Communications Commission vote to reverse the so called “net neutrality” regulation implemented during the Obama administration, we look at the law which the FCC is trying to enforce. We also examine our current lawmaker’s plans for Internet governance by listening to highlights of three hearings featuring testimony from lawyers from Facebook, Twitter, and Google. Please Support Congressional Dish Click here to contribute using credit card, debit card, PayPal, or Bitcoin Click here to support Congressional Dish for each episode via Patreon Mail Contributions to: 5753 Hwy 85 North #4576 Crestview, FL 32536 Thank you for supporting truly independent media! Bills H.R. 3989: Amend Foreign Intelligence Surveillance Act of 1978 S. 652 (104th): Telecommunications Acto of 1996 Additional Reading Article: House foreign surveillance turf war heats up as law sunset nears by Daniel R. Stoller, Bloomberg, December 1, 2017. Article: Colorado warns families to be prepared in case congress doesn't come through on CHIP funding by Kimberly Leonard, Washington Examiner, November 27, 2017 Article: Congress confronts jam-packed December with shutdown deadline looming by Mike Debonis and Ed O'Keefe, The Washington Post, November 26, 2017 Article: States prepare to shut down children's health programs if congress doesn't act by Colby Itkowitz and Sandhya Somashekhar, The Washington Post, November 23, 2017. Article: Here's how the end of net neutrality will change the internet by Klint Finley, Wired, November 22, 2017. Article: What is net neutrality? by Aaron Byrd and Natalia V. Osipova, NY Times, November 21, 2017. Article: Will the Telecommunications Act get a much-needed update as it turns 21? by Richard Adler, Recode, February 8, 2017. Article: Cable tv price increases have beaten inflation every single year for 20 years by Nathan McAlone, Business Insider, October 31, 2016 Article: 20 years after the Telecommunications Act of 1996, rekindling Congress's political will by Stuart N. Brotman, The Hill, February 8, 2016. Article: The city that was saved by the internet by Jason Koebler, Motherboard, October 27, 2016. Article: This was 1995: A pop culture snapshot by Patricia Garcia, Vogue, September 1, 2015. Article: Why your internet prices are bound to go up by Brian Fung, Washington Post, July 23, 2015. Report: In a nutshell: Net neutrality, CBS News, March 1, 2015. Report: AT&T buys DirectTV for $48.5 billion by Roger Yu, USA Today, May 18,2014. Article: Federal appeals court strikes down net neutrality rules by Brian Fung, Washington Post, January 14, 2014. Article: Legal gymnastics ensue in oral arguments for Verizon vs. FCC by Jennifer Yeh, Freepress, September 10, 2013. Report: Comcast completes NBC Universal merger, Reuters, January 29, 2011. References Bill Resources: H.R.1555 Communications Act of 1995 Bill Roll Call: H.R. 3989 Vote Roll Call FCC Resources: Telecommunications Act of 1996 Mission Statement: AIPAC - America's Pro-Israel Lobby Network Map: Community Networks Publication: Public Law 104 Telecommunications Act of 1996 Publication: The USA Liberty Act Report: Akamai's State of the Internet 2017 Report: FCC Fact Sheet Support Page: AT&T HBO Channels Visual References Cable Prices vs. Inflation, 1995-2015 Sound Clip Sources Senate Select Intelligence Committee: Facebook, Google and Twitter Executives on Russian Election Interference; November 1, 2017 (Senate Social Media) Witnesses: Colin Stretch - Facebook Vice President & General Counsel Sean Edgett - Twitter Acting General Counsel 1:49:24 Sen. Roy Blunt (MO): Mr. Stretch, how much money did the Russians spend on ads that we now look back as either disruptive or politically intended? It was at $100,000. Is that— Colin Stretch: It was approximately $100,000. Blunt: I meant from your company. Stretch: Yes, approximately $100,000. Blunt: How much of that did they pay before the election? Stretch: The— Blunt: I’ve seen the— Stretch: Yeah. Blunt: —number 44,000. Blunt: Is that right? Stretch: So— Blunt: 56 after, 44 before. Stretch: The ad impressions ran 46% before the election, the remainder after the election. Blunt: 46%. Well, if I had a consultant that was trying to impact an election and spent only 46% of the money before Election Day, I’d be pretty upset about that, I think. So, they spent $46,000. How much did the Clinton and Trump campaigns spend on Facebook? I assume before the election. Stretch: Yeah. Before the elec— Blunt: They were better organized than the other group. Stretch: Approximate—combined approximately $81 million. Blunt: 81 million, and before the election. Stretch: Yes. Blunt: So, 81 million. I’m not a great mathematician, but 46,000, 81 million, would that be, like, five one-thousandths of one percent? It’s something like that. Stretch: It’s a small number by comparison, sir. 2:19:55 Sen. Tom Cotton (AR): Do you see an equivalency between the Central Intelligence Agency and the Russian Intelligence Services? Sean Edgett: We’re not offering our service for surveillance to any government. Cotton: So you will apply the same policy to our Intelligence Community that you apply to an adversary’s intelligence services. Edgett: As a global company, we have to apply our policies consistently. Cotton: This reminds me of the old line from the Cold War, of one who did not see a distinction between the CIA and the KGB on the other hand, because the KGB officer pushed an old lady in front of an oncoming bus, and the CIA officer pushed the old lady out from the path of the oncoming bus, because they both go around pushing old ladies. I hope that Twitter will reconsider its policies when it’s dealing with friendly intelligence services in countries like the United States and the U.K. as opposed to adversarial countries like Russia and China. House Select Intelligence Committee: Facebook, Google and Twitter Executives on Russian Election Interference; November 1, 2017 (House Social Media) Witnesses: Kent Walker - Google Senior Vice President & General Counsel Colin Stretch - Facebook Vice President & General Counsel Sean Edgett - Twitter Acting General Counsel 39:05 Rep. Frank LoBiondo (R-NJ): Social-media platforms have the responsibility of striking a balance between removing false information and preserving freedom of speech. Can you give us some brief detail of how each of your companies plan to target perceived false news while protecting the robust political discourse? Kent Walker: Let me take that because that was the sort of next stage to my answer to Mr. Shift’s question. We are taking a number of different steps beyond advertising to focus on fake news. We are working to improve our algorithms, to provide additional guidance and training to the Raiders who provide quality feedback for us, and to look at a wider variety of signals to improve the ranking of authentic and genuine news on our sites and to demote sites that we feel are deceptive or misleading. We are also making broader use of fact-check labels, working with third parties, for both Google Search and Google News. And when it comes to advertising, we’ve taken steps to disallow advertising on sites that misrepresent their nature or purpose, and to add to our policies around or against hate speech, incitement of violence, and the like. Colin Stretch: I would group our efforts with respect to false news into three buckets. First, we find that most false news is financially motivated, and we’re making efforts to disrupt the financial incentives. That, we think, will make a big dent in it. Second, we’re looking to stop the spread of it. So when we have information that’s been disputed by independent fact-checkers, we limit the distribution and we alert users who are attempting to share it that it has been disputed. And third, we’re engaged in a number of user-education efforts to help, particularly around the world, users approach some of the content they see with a more discerning eye. Sean Edgett: We’re tackling this challenge in a few ways, and I think the way this was characterized is correct: it’s a balance between free speech and what’s real and what’s false. And we often see there’s a lot of activity on the platform to correct false narratives, and one of those things, for example, is the text-to-vote tweets that we turned over to you, which we took off our platform as illegal voter suppression. The number of tweets that were counteracting that as false and telling people not to believe that was, like, between eight and 10 times what we saw on the actual tweets. But we’re working on the behavior. That’s where we’re focused right now. We’ve had great strides in focusing on that for things like terrorism and child sexual exploitation. We’re trying to figure out how we can use those learnings to stop the amplification of false news or misinformation, and think we’re making great strides there, but it’s a definite balance. We also have work we’ve done, just like my peers, around ads transparency that, I think, is going to help educate the consumer about who’s paying for an ad, what else they’re running, what they’re targeting, what they’re after—especially around electioneering ads, who’s paying for it, how much they’re spending. We are also working with third parties. We have a Trust and Safety council of experts, academics, around the world who are helping us think through the things that we’re trying to employ to tackle these issues and how they will impact the debate and free speech on our platform. So we’re working hard on this, but it’s a challenge. 59:39 Rep. Terri Sewell (D-AL): I submit to you that your efforts have to be more than just about finding malicious and deceptive activity, that you have a responsibility—all of you have a responsibility—to make sure that we are not adding to the problem by not being as rigorous and as aggressive as we can in terms of vetting the content and in terms of making sure that we are being really dynamic in doing that. And I also want to just say that I think it’s ridiculous that a foreign entity can buy a political ad with rubles but can’t give a political contribution to me—a Russian person can’t give me a political contribution. There seems to be some legislation that needs to be had here, is all I’m saying. 1:16:05 Rep. Mike Quigley (D-IL): Let’s look at unpaid content for a second. Sometimes these fake accounts are pulled down, but the fake story takes the false claims of widespread voter fraud, for example, generated by these accounts have spread thousands of thousands of times, often picked up by legitimate news accounts. What do you do to flag that? What do you sense is your responsibility? And before any of you answer, let me just notice this, that if we’re asking is, are we still in this situation? As of just a short time ago—and I’m talking about when this meeting started—on Twitter, if you clicked on the hashtag “NYCTerroristAttack,” which is “trending,” marked with a red button saying “live,” the top tweet links to an Infowars story with the headline, “Imam: I Warned De Blasio About New York City Terror; He was Too Busy Bashing Trump.” This is a real-time example of when we talk about this information being weaponized. How quickly can you act, and what’s your responsibility to set the record straight so that the people who saw this know that it’s fake news and at least at some point in time it can’t keep spreading like some sort of virus through legitimate world? Sean Edgett: That’s something we’re thinking about all the time because it’s a bad user experience, and we don’t want to be known as a platform for that. In your example, in for instance, the system self-corrected. That’s not—that shouldn’t be the first tweet you see anymore. It should be a USA article, the last time I checked. Quigley: But you saw this. Edgett: USA Today. At lunch I did, yeah, and I also saw the system correct it. Quigley: Can you give me a really good guess on how long it was top? Edgett: We can follow up with you and your staff on that, and I don’t have the stat in front of me. Quigley: Yeah. Edgett: So I don’t know. But we are, like we said earlier, trying to balance free speech with making the information you see on the system—especially around trends that we direct you to, so if you’re clicking on a hashtag, we want to make sure you’re seeing verified accounts and accurate information and reporting. Sometimes it doesn’t work as we intended. We learn from those mistakes and tweak and modulate going forward. Quigley: Beyond the correction, do you have a responsibility to flag something as “this was fake news”? Edgett: We see our users do that a lot. We’re an open, public platform with respect to journalists and other organizations who point these things out. You may have seen that on this instance, for example. Quigley: Yeah, if someone’s breaking the law, you’ve got to feel like you have a responsibility to do something about that. It’s not—as you said, this is a—with this extraordinary gift, this platform of free expression, comes the responsibility you all talked about. So, if you know something’s illegal, you know you have the responsibility to do something. At what point does this become something where you can’t just correct it; you’ve got to say to the public, this isn’t true. Edgett: Right. And we take swift action on illegal content, illegal activity, on the platform. A good example of this is the text to vote, voter suppression tweets that we’ve turned over to this committee. We saw swift action of the Twitter community on disputing those claims; and Twitter actively tweeted, once it discovered these things were on the platform, to notify our users that this was fake information, that you could not, in fact, vote by tweet, and pointing people to a tool that would allow them to find their nearest polling place. That tweet— Quigley: Is this [unclear] because that was illegal activity, or is this—if something’s just fake, do you think you have an equal responsibility? Edgett: We took that down because it was illegal voter suppression. We are actively working on, how do we balance what is real and fake, and what do we do in the aftermath of something being tweeted and re-tweeted, like you said, and had people even seen it and how do we make sure that they’re seeing other view points and other facts and other news stories. Quigley: Do you have a policy right now where if you know something’s out there that’s not true, of saying so? Edgett: We do not. We have a policy that fosters the debate on the platform. We have a policy that takes down a lot of that content because it comes from automated malicious accounts or spammers. That stuff we’re removing and acting on as quickly as we can. Quigley: And I understand how you’re trying to distinguish that, but the fact is if something’s fake, it doesn’t matter if it’s from a fake account or some bot or something. If it’s just not true and it’s wildly obvious, before it goes viral and gets picked up legitimate, you must feel like you have some responsibility. Edgett: We are—we are deeply concerned about that and figuring out ways we can do it with the right balance. 1:57:39 Rep. Jackie Speier (D-CA): RT, Russia Today, on your platform, has 2.2 million subscribers. Fox News, on your platform, has 740,000 subscribers. CNN has 2.3 million subscribers. The Intelligence Community assessment that was made public in January spoke about RT, and it said, “RT conducts strategic messaging for Russian government. It seeks to influence politics and fuel discontent in the United States.” So my question to you is, why have you not shut down RT on YouTube? Kent Walker: Thank you, Congresswoman. We’ve heard the concerns, and we spoke briefly about this previously. We recognize that there’re many concerned about RT’s slanted perspective. At the same time, this is an issue that goes beyond the Internet to cable, satellite television and beyond. We have carefully reviewed RT’s compliance with our policies. We’ve not found violations of our policies against hate speech and incitement to violence and the like. Speier: It’s a propaganda machine, Mr. Walker. The Intelligence Community—all 17 agencies—says it’s an arm of one of our adversaries. Walker: And we agree that— Speier: I would like for you to take that back to your executives and rethink continuing to have it on your platform. Walker: Yes. We agree that transparency’s important for all of these different sources of information. We are working on additional ways to provide that for all government-funded sources of information, including Al Jazeera and a range of government organizations. 2:05:27 Rep. Trey Gowdy (R-SC): Is it constitutionally protected to utter an intentionally false statement? Colin Stretch: So, it depends on the context, but there is recent Supreme Court precedent on that. On Facebook— Gowdy: On which side: that it is or is not? Stretch: That it is, in most cases, protected. However, on Facebook, our job is not to decide whether content is true or false. We do recognize that false news is a real challenge. The way in which we’re addressing it is by trying to disrupt the financial incentives of those who are profiting from it, which is where most of it comes from. Most of this, most of the fake-news problem is coming from low-quality websites that are trying to drive traffic on every side of every issue, and by disrupting the financial incentives, we’re able to limit the distribution. We’re also trying to make sure that users do know when a story has been disputed by a neutral third party and alerting users to that fact— I’ll stop. I’ll stop there. Gowdy: Well, I’m smiling only because on the last break a couple of my colleagues and I were wondering who those neutral fact-checkers are, and I really do appreciate your desire to want to have a neutral fact-checker. If you could let me know who those folks are, I’d be really grateful, because people in my line of work might take exception with the neutrality of some of the fact-checkers. So, if I understand you correctly, the authenticity of the speaker is very important; the accuracy of the content, less so. Stretch: That’s how we approach it. That’s exactly right. Gowdy: All right. For the life of me, I do not understand how a republic is served by demonstrably, provably, intentionally false information. And I get it, that you don’t want to be the arbiter of opinion—I don’t want you to be, either—but today’s not Thursday, so if I say it is, I swear I don’t understand how my fellow citizens benefit from me telling them something that is demonstrably false, and I am saying it with the intent to deceive. I just—for the life of me, I don’t get it, but I’m out of time. Senate Judiciary Subcommittee on Crime and Terrorism: Facebook, Google and Twitter Executives on Russian Disinformation; October 31, 2017 (Social Media) Witnesses: Colin Stretch - Facebook Vice President and General Counsel Sean Edgett - Twitter Acting General Counsel Richard Salgado - Google Law Enforcement & Information Security Director Clint Watts - Foreign Policy Research Institute, National Security Program Senior Fellow Michael Smith -New America, International Security Fellow 38:25 Sen. Sheldon Whitehouse (RI): And I gather that all of your companies have moved beyond any notion that your job is only to provide a platform and whatever goes across it is not your affair. Colin Stretch: Senator, our commitment to addressing this problem is unwavering. We take this very seriously and are committed to investing as necessary to prevent this from happening again. Absolutely. Whitehouse: Mr. Edgett? Sean Edgett: Absolutely agree with Mr. Stretch, and this type of activity just creates not only a bad user experience but distrust for the platform, so we are committed to working every single day to get better at solving this problem. Whitehouse: Mr. Salgado? Richard Salgado: That’s the same for Google. We take this very seriously. We’ve made changes, and we will continue to get better. Whitehouse: And ultimately, you are American companies, and threats to American election security and threats to American peace and order are things that concern you greatly, correct? Stretch: That is certainly correct. Edgett: Agree. Salgado: That’s right. 52:15 Sen. Dianne Feinstein (CA): Mr. Salgado, why did Google get preferred status to Russia Today, a Russian propaganda arm, on YouTube? Richard Salgado: There was a period of time where Russia Today qualified really because of algorithms to participate in an advertising program that opened up some inventory for them, subjective standards around popularity and some other criteria to be able to participate in that program. Platforms or publishers like RT drop in and out of the program as things change, and that is the case with RT. They dropped out of the program. Feinstein: Well, why didn’t you revert RT’s preferred status after the ICA came out in January 2017? It took you to September of 2017 to do it. Salgado: The removal of RT from the program was actually a result of, as I understand it, is a result of some of the drop in viewership, not as a result of any action otherwise. So, there was nothing about RT or its content that meant that it stayed in or stayed out. 2:03:15 Sen. Mazie Hirono (HI): So, Mr. Stretch, you said that there are 150 people at Facebook just focused on the content of what’s on your platform. How many people do you have, Mr. Edgett, at Twitter to concentrate on the content and ferretting out the kind of content that would be deemed unacceptable, divisive? I realize there are a lot of First Amendment— Sean Edgett: Right. Hirono: —complicated issues, but how many people do you have? Edgett: Well, we harness the power of both technology, algorithms, machine learning to help us, and also a large team of people, that we call our Trust and Safety team and our User Services team, it’s hundreds of people. We’re at a different scale than Facebook and Google, obviously, but we’re dedicating a lot of resource to make sure that we’re looking at user reports about activity on the platform that they think is violent or activity on the platform they think is illegal, and prioritizing that accordingly. Hirono: So, you have fewer people than Facebook. Facebook has 150; you said you have hundreds. Edgett: Yeah, we have hundreds— Hirono: Hundreds. Edgett: —across User Services and Trust and Safety, looking at the issues of content on the platform. Hirono: What about you, Mr. Salgado? Richard Salgado: Google has thousands of people. There’s many different products, and different teams work on them, but internally we’ll have thousands of people working on them. We also get a good deal of leads on content that we need to review for whether it’s appropriate or not that come from outside the company as well. Hirono: You have thousands of people just focused on the content— Salgado: On various types of content. Hirono: —as Mr. Stretch indicated to us that he has at Facebook? You have thousands of people dedicated? Salgado: We have thousands of people dedicated to make sure the content across our—and remember, Google has many different properties within it—but, yes, the answer is we have thousands that look at content that has been reported to us as inappropriate. Hirono: So, in view of that, Mr. Stretch, do you think 150 people is enough people? Stretch: Senator, to be clear, the 150 people I mentioned earlier is people whose full-time job is focused on addressing terrorism content on Facebook. In terms of addressing content on the site generally, we have thousands. And indeed, we have a Community Operations team that we announced earlier this year that we were going to be adding additional thousands to the several thousands that are already working on this problem every day. Hirono: I think it’s pretty clear that this is a whole new sort of use, or misuse, of your platform, and you may have various ways to address terrorist content, but this is a whole other thing. 2:32:10 Clint Watts: Account anonymity in public provides some benefits to society, but social-media companies must work to immediately confirm real humans operate accounts. The negative effects of social bots far outweigh any benefits that come from the anonymous replication of accounts that broadcast high volumes of misinformation. Reasonable limits on the number of posts any account can make during an hour, day, or week should be developed and human-verification systems should be employed by all social-media companies to reduce automated broadcasting. 2:33:07 Clint Watts: Lastly, I admire those social-media companies that have begun working to fact-check news articles in the wake of last year’s elections. These efforts should continue but will be completely inadequate. Stopping false information—the artillery barrage landing on social-media users comes only when those outlets distributing bogus stories are silenced. Silence the guns, and the barrage will end. I propose the equivalent of nutrition labels for information outlets, a rating icon for news-producing outlets displayed next to their news links and social-media feeds and search engines. The icon provides users an assessment of the news outlet’s ratio of fact versus fiction and opinion versus reporting. The rating system would be opt-in. It would not infringe on freedom of speech or freedom of the press. Should not be part of the U.S. government, should sit separate from the social-media companies but be utilized by them. Users wanting to consume information from outlets with a poor rating wouldn’t be prohibited. If they are misled about the truth, they have only themselves to blame. 2:44:20 Sen. Sheldon Whitehouse (RI): Mr. Watts, you’ve been a U.S. Army infantry officer, you’ve been an FBI special agent on the Joint Terrorism Task Force, you’ve been executive officer of the Combating Terrorism Center at West Point, and you’ve been a consultant to the FBI’s Counterterrorism Division and National Security Branch, so you clearly take American national security very seriously. It is, and has been, your life’s work. So, when you say, ”The Kremlin disinformation playbook,” which we’re talking about here, “will also be adopted by authoritarians, dark political campaigns, and unregulated global corporations who will use this type of social-media manipulation to influence weaker countries; harm less-educated, vulnerable populations; and mire business challengers,” you’re not just talking about the Russian election-manipulation operation getting worse and having to be contained. You’re talking about it as if it’s a technology that other bad actors can adopt and have it metastasized entirely into new fields of dissimulation, propaganda, and so forth. Clint Watts: Yes. Whitehouse: Correct? Watts: Everybody will duplicate this if they don’t believe in the rule of law, if they want to destroy democracies from the inside out. Anyone with enough resources and time and effort, if they put it against us, they can duplicate this. I could duplicate it if I chose to. Whitehouse: So, if we don’t stop it now, it’s going to get exponentially worse. Watts: Yes. And I think the one thing that we should recognize is even in the U.S. political context, if we don’t put some sort of regulation around it, if bodies like this don’t decide how we want American politics to work, everybody will be incentivized to use this same system against their political opponents, and if you don’t, you will lose. 2:51:35 Sen. John Kennedy (LA): The First Amendment implications of all of this concern me as well. I mean, what’s fake news? What do you think fake news is? Clint Watts: Fake news, over the years since I’ve been involved and talking about this, is any news the other side doesn’t like, doesn’t matter what side it is. Kennedy: That’s right. Michael Smith: Senator, if I may. I’m teaching undergrads a course at Georgia State University this semester titled Media, Culture, and Society; and we’re about to start classes focused on fake news later this week. I would submit that fake news might best be defined as deliberate mis- or disinformation, which is tailored or engineered to achieve a particular outcome in the way of behaviors, to persuade perceptions in a manner that lead to behaviors such as perhaps a vote for or against somebody. Kennedy: Well, that’s a good definition, but I’ll end on this: in whose opinion? Watts: But I think there are parameters that we could come around. I mean, reporting versus opinion is a key point of it. I think also in terms of fact versus fiction, I’ve actually set up rating systems on foreign media outlets before the U.S. Government’s paid me to do that, you know, in the Iraq/Afghanistan campaigns. House Energy and Commerce Communications and Technology Subcommittee: FCC Oversight; October 25, 2017 Witnesses: Ajit Pai: FCC Chairman 14:00 Rep. Greg Walden: Ultimately, Congress is the appropriate forum to settle the net neutrality debate. I think you hear a little of that passion here on both sides. And I’ve been continuing my efforts to negotiate a compromise. Although my staff continues to engage in the various affected parties in productive discussions toward that end, my colleagues in the minority have, unfortunately, seemed largely uninterested at this point. Love to see that change, by the way. Door remains open. We’re willing and able to codify net neutrality protections and establish a federal framework in statute for providing certainty to all participants in the Internet ecosystem. I don’t think we need Title II to do that. 1:31:45 Rep. Bob Latta (R-OH): Voice-activated virtual assistants like Siri, Alexa, and Google Assistant are becoming an increasingly popular consumer gateway to the Internet. Some day soon they might even become consumer-preferred interface with the Internet, leaving the age of the desktop Google Search behind. You get Yelp results in Siri, OpenTable in Google, TuneIn radio from Alexa. These interactions are occurring through private partnerships among these companies to have their apps interact. However, it creates a situation where, by definition, the consumers’ access to other Internet content is limited or completely blocked. It’s the question of, who answers Siri’s question when you ask Siri something? Chairman Pai, can the FCC do anything about this? Ajit Pai: Congressman, under our current Internet regulations, we cannot. Those do not apply to edge providers. 1:36:12 Rep. Anna Eshoo (D-CA): Will you commit to us that you’ll apply or consider applying broadcast-transparency requirements to state-sponsored media outlets like RT? And if not, why not? Ajit Pai: Congresswoman, thank you for the question. As I under— Eshoo: Uh-huh, you’re welcome. Pai: As I understand the law— Eshoo: Uh-huh, mm-hmm. Pai: —there is no jurisdictional hook at this point, no transfer of a license, for example, that allows the FCC to a certain jurisdiction. Eshoo: But what about those that have a license and carry them? Do you have—doesn’t the FCC have any say so in that, or is this, as the Intelligence Community said, that they are a principle international propaganda outlet? So are they just going to operate in the United States no matter what? Pai: Congresswoman, again, under the Communications Act and the Constitution, the First Amendment, we do not have currently a jurisdictional hook for taking and doing an investigation of that kind. If you’re privy to, obviously, classified or unclassified information that suggests that there might be another agency that has, obviously, a direct interest in the issue—and we’re, obviously, happy to work with them—but at the current time, as I’ve been advised, neither under the First Amendment nor under the Communications Act do we have the ability to— Eshoo: Well, First Amendment applies to free speech in our country. It doesn’t mean that the Kremlin can distribute propaganda in our country through our airwaves. I just—I don’t know if you’re looking hard enough. 1:40:05 Rep. Brett Guthrie (R-KY): In 2013, and I was one of the households affected by this, there was a carriage dispute between CBS and Time Warner Cable. And CBS blocked Time Warner Cable Internet customers from viewing its shows online through a CBS.com website. So I couldn’t get any of CBS or SHOWTIME or any of that on TV. If you went to the website, because Time Warner Cable was our cable provider and Internet service provider, you couldn’t go to CBS.com—it was blocked. Or SHOWTIME to watch any of the shows that was coming out. And that was when some new ones were coming out that August, so we were trying to find that. But some members of Congress said, bring this up, and I think Chairwoman Clyburn was acting chairwoman at the time and said that she didn’t believe the agency had the jurisdiction to intervene in this situation. And Chairman Pai, do you think if it happened now, do you think the FCC would have the opportunity to intervene in a similar case? Ajit Pai: Congressman, I think the legal authorities have not changed to the extent that the FCC gets a complaint that a party is acting in bad faith in the context of retransmission dispute, then we would be able to adjudicate it. But absence to such a complaint or additional authority from Congress, we couldn’t take further action. Guthrie: But currently the Title II, open Internet, is still in effect. Is that—how would that affect it? Pai: Oh, currently, yes. Just to be clear, I should have added was well then, our Internet regulations would not apply to that kind of content to the extent you’re talking about, the blocking of online distribution of [unclear]. Guthrie: Because it only applies to the service provider, not to the content provider? Pai: That is correct, sir. Federal Communications Commission: Open Internet Rules; February 26, 2015 (Open Internet Rules) Witnesses: Agit Pai: FCC Commissioner 38:05 Ajit Pai: For 20 years, there has been a bipartisan consensus in favor of a free and open Internet. A Democratic president and Republican Congress enshrined in the Telecommunications Act of 1996 the principle that the Internet should be a vibrant and competitive free market “unfettered by federal and state regulation.” And dating back to the Clinton administration, every FCC chairman—Republican and Democrat—has let the Internet grow free from utility-style regulation. The results speak for themselves. But today the FCC abandons those policies. It reclassifies broadband Internet access service as a Title II telecommunications service. It seizes unilateral authority to regulate Internet conduct to direct where Internet service providers, or ISPs, make their investments and to determine what service plans will be available to the American public. This is not only a radical departure from the bipartisan market-oriented policies that have serviced so well over the past two decades, it is also an about-face from the proposals the FCC itself made just last May. So why is the FCC turning its back on Internet freedom? Is it because we now have evidence that the Internet is broken? No. We are flip-flopping for one reason and one reason only: President Obama told us to do so. Barack Obama: I’m asking the FCC to reclassify Internet service under Title II of a law known as the Telecommunications Act. Pai: On November 10, President Obama asked the FCC to implement his plan for regulating the Internet, one that favors government regulation over marketplace competition. As has been widely reported in the press, the FCC has been scrambling ever since to figure out a way to do just that. The courts will ultimately decide this order’s fate. Litigants are already lawyering up to seek a judicial review of these new rules. And given this order’s many glaring legal flaws, they’ll have plenty of fodder. 40:46 Ajit Pai: This order imposes intrusive government regulations that won’t work, to solve a problem that doesn’t exist, using legal authority the FCC doesn’t have. Accordingly, I dissent. 1:03:15 Ajit Pai: And I’m optimistic that we will look back on today’s vote as an aberration, a temporary deviation from the bipartisan consensus that has served us so well. I don’t know whether this plan will be vacated by a court, reversed by Congress, or overturned by a future commission, but I do believe its days are numbered. Telecommunications Bill Signing: February 8, 1996 (Bill Signing) 4:59 Vice President Al Gore: I firmly believe that the proper role of government in the development of the information superhighway is to promote and achieve at every stage of growth, at every level of operation, at every scale, the public interest values of democracy, education, and economic and social well-being for all of our citizens. If we do not see to it that every project, every network, every system addresses the public interest at the beginning, then when will it be addressed? How can we expect the final organism to express these values if they are not included in its DNA, so to speak, at the beginning? For that reason, in 1993, on behalf of the president, I presented five principles that the Clinton administration would seek in any telecommunication reform legislation: private investment, competition, universal service, open access, and flexible regulations. Telecommunications Act Conference: December 12, 1995 (Conference) 22:15 Rep. Rick Boucher: In the very near future, most homes are going to have two broadband wires that will offer the combination of telephone service and cable TV service. One of those will have started as a telephone wire; the other will have started as a cable television wire. The programming that is affiliated with the owners of those wires obviously is going to be available to consumers in the homes, but other programmers may very well be denied access. And if access to other programming is denied, consumers will be deprived of video offerings to which they should be entitled. Telecommunications Act Conference: December 6, 1995 (Conference) 27:14 Rep. Henry Hyde (R-IL): No one has a right to give pornography to children. While we have not previously criminalized this area on the federal level, it’s necessary to do so now. This is because of the advent of the Internet, which enables someone in one location to instantly send or make available pornography to children in every city in America. Children don’t have the right to buy pornography in any store in America, yet some would argue there’s a right to give it to them free, delivered to their home by computer. Telecommunications Act Conference: Telecommunications Reform Act of 1995; October 25, 1995 8:58 Sen. John McCain: I believe the Senate bill in its present form is far too regulatory. Any bill that gives 80 new tasks to the Federal Communications Commission, in my view, does not meet the standard that we have set for ourselves of trying to allow everyone to compete in a deregulated—in an environment that is changing so quickly that none of us predicted five years ago that it would look like it is today. And today we have no idea what the industry will look like in five years. 32:00 Rep. Steve Buyer (R-IN): One thing that does please me is when I think about one of the last renaissance of electricity, electricity goes to the big cities and leaves out the rural areas, and then we have to come up with the REMCs. When we move America to the World Wide Web, though, we’re not allowing cherry-picking and to move to the great resources in the big cities, but the rural areas will be included in the World Wide Web. And so I congratulate both of you to making sure that that happens, that some of the strength of this country lies in the heart of America, and I think that’s pretty exciting. House Commerce Subcommittee on Telecommunications and Finance: Telecommunications Act Part 1; May 11, 1995 1:25:36 Rep. Dan Schaefer (R-CO): Unlike the case for telephone service, every American household has access to at least one, and soon many more, competitive video providers today. The case simply has not yet been made that the federal government has a duty to do anything other than provide for access to alternative in the case of a purely entertainment service like the upper tier of cable. We have provided that access. We will expand that access in this bill. It is time we focus on the real issues addressed by 1555, the building of advanced broadband networks and the benefits that it will bring to all Americans. House Energy & Commerce Committee: Cable Television Deregulation; February 2, 1994 Witnesses: Bill Reddersen - Bell South Corporation Senior Vice President Jeffery Chester - Center for Media Education Executive Director Edward Reilly - President of McGraw-HIll Broadcasting 7:27 Rep. Rick Boucher (D-VA): As telephone companies are able to offer cable TV service inside their telephone-service areas, they’ll have the financial incentive to deploy the broadband technology that will facilitate the simultaneous transport of voice and cable TV service and data messages, building out the infrastructure, creating the last mile of the information highway, that distance from the telephone company’s central office into the premises of the user homes and businesses throughout the nation. 24:36 Bill Reddersen: It is our goal to have you pass legislation this year that enables us to deploy a second broadband network that will compete effectively with cable and bring consumers new and innovative educational healthcare information and entertainment services. 25:12 Bill Reddersen: However, unless you eliminate the competitive advantages this bill confers upon cable companies, our industry will not be able to compete effectively against companies that already have a dominant, if not monopoly, position in programming markets, nor will the bill encourage telephone companies to make or continue the substantial investments required for widespread development of broadband networks. Cable companies are formidable competitors and do not need protection. Cable is a 21-billion-dollar-a-year-gross business, passing over 90% of U.S. homes. According to a recent survey, only 53 out of over 10,000 cable systems compete against a second cable operator. Cable has vertically integrated and diversified into multi-billion-dollar programming and communications businesses. Cable companies and the emerging cable telco alliances clearly do not need protection from telephone companies that currently have no video programming market share, virtually no broadband facilities to the home, and little or no operational experience in the video marketplace. 37:55 Jeffrey Chester: While we share the goal of this committee that every community be served by at least two wires, there are no guarantees that this will be achieved in the near future, even with the proposed legislation. We are also troubled by the unprecedented wave of mergers and acquisitions taking place in the media industries. Serious concerns are raised by the emergence of new media giants controlling regional Bell operating companies, cable systems, TV and film studios, newspapers, broadcasting properties, and information service providers. Without federal intervention, control of the nation’s media system will be in the hands of fewer and less-accountable companies, possessing even more concentrated power. 40:45 Bill Reddersen: Just as we have established private librar—public libraries—and public highways, we need to create public arenas in the electronic commons in the media landscape. A vibrant telecommunication civic sector will be an essential counterbalance to the commercial forces that will dominate the information superhighway. 2:24:38 Bill Reddersen: The common carrier requirements of this legislation are essentially, if executed the way they have in the telephone industry, the second model that you articulated, and that is that if additional capacity was required and someone shows up, we build. Okay? That is the fundamental premise underlying common carrier regulation. 2:30:04 Rep. Michael Oxley (R-OH): Does it really matter if BellSouth builds the wire, the limitless wire, or the cable industry builds the limitless wire if indeed it is essentially a limitless technology that is open to everyone who wants to sell his or her product, including Mr. Reilly, on that particular technology? If you have the common carrier status and you have the ability to deliver your programming, is it really relevant whether BellSouth owns the wire or Mr. Angstrom owns the wire, and if it is indeed relevant, why is it relevant, Mr. Reilly? Edward Reilly: Well, it’s relevant in any instance where the company that owns the wire is also engaged in the programming business at all. If someone is prepared to build a wire and agree that they would never want to be in the programming business, and that we were given very strong safeguards— Oxley: Why is that a problem? Reilly: Well, because we end up inevitably competing with our programming— Oxley: Of course you do. Reilly: —against someone who owns both the wire and the programming content that goes on that wire. Reilly: Why is it relevant, though, if BellSouth owns the wire and you’ve got limitless access and limitless capacity, why does it make any difference that the people who supposedly own the wire are competing against you? They’re competing head to head. You are simply paying the same shelf space for your product as the owner of the product that’s providing that kind of service. Oxley: Well, we have—we believe that there is ample opportunity in that type of environment for a number of anti-competitive activities that would certainly damage our ability to try and be an equal player. Where we get positioned on the wire, what comes up when the menu first comes up, how the billing is organized—there’s a whole host of issues that go along with owning the wire and setting up the infrastructure that can create a significant competitive advantage to someone who chooses to use that for their own program service. 2:38:47 Rep. Billy Tauzin (D-LA): I think the key for us here is to guarantee that there are comparable providers of services and how they get it to us, as long as it’s comparable and we have choice and all people have access to it. If we guarantee that kind of policy for America, we don’t much have to worry about the risk. Consumers take over from there as long as we guarantee, if we do have common carriage on a line, that the owner of the line can’t discriminate; can’t play games with the competitors who own that line; that you can’t play bottleneck games, as publishers are complaining about in the other bill we’re going to debate pretty soon on MMJ; that, in fact, there’s fairness on the playing field. Here’s a question for you in regard to that fairness: If the telephone companies or the utility companies can in fact do what you can’t do—produce their own programs and send them over those lines, even if we restrict them in the number of channels they can use, which I really have a problem with, as Mr. Boucher does—are we going to make sure that the same provisions of program access apply to those producers of programs that we’ve applied to the cable producers? You raised the issue in your testimony. You talked about the problems we had in cable where they own both the software and the hardware—in essence, the content and the conduit—and the problems consumers had as a result of that. Are we going to require the cable companies make 75% of their channels available to competitors? Are we going to require that the utility companies, when they build lines, fiber optic lines, are going to be similarly required to make access available to their competitors? If we’re talking about a real competitive world here, are we going to build a world where some have obligations others don’t have? Some must carry and some don’t? Some must give access to their programs to competitors, as cable is now required to do because of the bill we successfully passed over the president’s veto last year, and over cable’s objection? Are we going to make that same requirement now available—enforced upon other competitors who build wires, or who build some other systems, who decide to deliver it under some particle-beam technology we haven’t dreamed of yet, or the satellite delivery systems that are coming into play? Are we going to create some real equality in this competition, that’s going to give consumers comparable choices? That’s the key word to me—comparable choices. Are we going to do that? Or are we going to dictate the technology, confine you to so many channels, not require you to carry what others have to carry, put requirements on one competitor—the cable company can get on the telephone company’s lines, but the telephone company can’t get on the cable system’s line? Come on. It seems to me if we’re going to build policy that gets consumers real, comparable choices out there, we have to answer all those questions. Video: What the world looks like without net neutrality Video: Net Neutrality II: Last Week Tongight with John Oliver Special Thanks! To Adam Hettler for performing The Most Dangerous time of the Year! See more of Adam here! Background music for The Most Dangerous Time of the Year. Cover Art Design by Only Child Imaginations Music Presented in This Episode Intro & Exit: Tired of Being Lied To by David Ippolito (found on Music Alley by mevio)  

Corbin A. Smith (Take It Or Break It podcast, VICE, The Shocker) joins Sean & Joey to break down NBA news, roast the Roundball Rock podcast, and deliver a red-hot Reggie Miller take. Along the way we learn about Portland's terrible mascot, Jusuf Nurkic's love of pour-over coffee, why Nikola Jokic is a fraud, why pooping while dunking is cool, Memo Okur's ties to Erdogan, transcribing Clay Travis, and that Suncoast Motion Picture Company still exists. Also we play "What Is Bill Walton Doing Right Now?" See acast.com/privacy for privacy and opt-out information.

In the first character discussion in over a year, the Invincible Podcast crew sits down to discuss one of the greatest villains in Invincible, Angstrom Levy. Follow along as they cover everything, from his origin in Issue #16 to each of his attempts at defeating Mark. New York Comic Con 2017 and it's announcements are also discussed this episode, including the final cover reveal...Issue #144! Email: TheInvinciblePodcast @ Gmail Twitter: @InvincibleCast Facebook: @InvinciblePodcast Art by: Ryan Ottley & Jeremiah Skipper Music by: 8-Bit Ninjas

The Nucleosome is the basic building unit of chromatin. It consists out of 147 base pairs of double stranded DNA wrapped around the Histone core octamer that consists out of 2 copies of each dimer of H2A/H2B, and H3/H4. Nucleosomes are organized like "beads on a string" to form a modifiable regulatory basis for higher order structures of chromatin. The first images of the nucleosome as a particle was published by our guests Ada and Don Olins from the University of New England in 1974 (Olins, A. L. & Olins, D. E. Spheroid Chromatin Units (ν Bodies). Science 183, 330–332 (1974).). This observation lead the way to numerous discoveries around chromatin which ultimately culminated in the discovery of the 2.8 Angstrom high-resolution crystal structure 20 years ago in the year 1997 (Luger, K., Mäder, A. W., Richmond, R. K., Sargent, D. F. & Richmond, T. J. Crystal structure of the nucleosome core particle at 2.8 Å resolution. Nature 389, 251–260 (1997).) References for this episode Ada L. Olins, Donald E. Olins. Spheroid Chromatin Units (ν Bodies). Science. 25 Jan 1974: Vol. 183, Issue 4122, pp. 330-332. DOI: 10.1126/science.183.4122.330 Ada L. Olins, Donald E. Olins, et al. An epichromatin epitope. Nucleus. 2011 Jan-Feb; 2(1): 47–60. DOI: 10.4161/nucl.2.1.13271 Active Motif Contact Details Follow us on Twitter Join us on LinkedIn Like us on Facebook Email us @Active Motif Europe or Active Motif North America.

People who make unfortunate choices: we got 'em in spades in this episode! Would John Updike's tiresome American everyman Harry "Rabbit" Angstrom or too-quirky Michigan football coach Jim Harbaugh make you a better hangover breakfast? Join Janelle and Tami as they have... enough... to drink and try to decide who would best help them recover the next day.

This thesis has focused on observational studies of galaxy evolution. We combine multiwavelength data to derive various physical properties of nearby galaxies. In particular, we study the recent star formation histories (SFHs) of galaxies from their optical spectra, and the relations between molecular gas and star formation of galaxies from their radio, ultraviolet, and infrared observations. First, we constrain the radial dependence of the recent SFHs of about 200 local galaxies with the long-slit spectroscopy data by fitting stellar population models to the combination of specific star formation rate (sSFR), 4000 Angstrom break strength and Balmer absorption lines. The late-type and early-type galaxies show distinct behaviors in their recent star formation histories. In late-type systems, bursts occur both in the inner and in the outer regions of the galaxy. The fraction of stars formed in a single burst episode is typically around 15% of the total stellar mass in the inner regions of the galaxy and around 5% of the mass in the outer regions. On the other hand, bursts occur predominantly in the outer disk in massive and bulge-dominated galaxies, and the fraction of stars formed in a single episode is only 2 - 3% of the underlying stellar mass. One of the most fundamental questions in modern astrophysics is how galaxies convert their gas into stars, and how this process may change with the galaxy internal properties and/or across cosmic time. We study the variations in molecular gas depletion time (tdep), defined as the molecular gas mass divided by the star formation rate (SFR), and which tells us how fast the gas will be consumed under the current SFR. We establish that the main parameter dependence of tdep is upon sSFR on both local and global scales. The strong correlation between tdep and sSFR extends continuously over a factor of 10 in tdep and from log sSFR = -11.5 to -9, i.e., from nearly quiescent patches of the disc to disc regions with very strong star formation. This leads to the conclusion that the local molecular gas depletion time in galactic disks is dependent on the local fraction of young-to-old stars and that galaxies with high current-to-past-averaged star formation activity, will drain their molecular gas reservoir sooner. We further study the impact of galaxy internal structures such as the bulge, arm, bar and ring on the variation of tdep on kiloparsec and global scales. The displacements in the main tdep-sSFR plane for different structures is linked to the variations in stellar, rather than gas surface densities: regions with high stellar surface densities such as the central bulges of galaxies have a reduced tdep at a given sSFR, while regions with low stellar surface densities such as the disk of galaxies have a longer tdep at a given sSFR. We provide our best current predictor for tdep, both globally and for 1kpc grids.

A jam-packed episode this week. We talk about the first of Updike's Rabbit books, Mike gives an update on his NaNoWriMo adventure, we consider whether quality television dramas are putting the heat on novelists, and we've also got our first-ever Rating Reconsidered. Buckle up! For more, and to donate to our fund drive, visit us online at bookfightpod.com. 

Princeton and UC Berkeley trained chemist Delia Milliron is the Deputy Director of the Molecular Foundry at Lawrence Berkeley Lab. In part one, Delia explains Nano Science and Technology. She talks about her research with nanocrystals to make thin films. foundry.lbl.govTranscriptSpeaker 1: Spectrum's next. Speaker 2: Mm mm mm mm mm mm mm Speaker 3: [inaudible].Speaker 1: Welcome [00:00:30] to spectrum the science and technology show on k a l x Berkeley, a biweekly 30 minute program bringing you interviews featuring bay area scientists and technologists as well as a calendar of local events and news. Speaker 4: Good afternoon. My name is Brad Swift. I'm the host of today's show. Today is part one of a two part interview with Delia Mil Iron, the deputy director of the Lawrence Berkeley national lab molecular foundry, [00:01:00] Delia mill iron is a chemist. She received her undergraduate degree from Princeton and her phd from UC Berkeley. Delia leads a research group at the molecular foundry which has recently spun off a startup named heliotrope technologies for group is a partner in the newly announced Joint Center for Energy Storage Research, a multistate department of energy research hub focused on developing transformative new battery technology. Delios group was recently awarded a $3 million grant [00:01:30] by the Department of Energy Advanced Research projects, agency dash energy by e for her work on smart window technologies onto the interview. Delia mill iron. Welcome to spectrum. Speaker 5: Thank you.Speaker 4: I suspect that most of our listeners have heard of nanoscience but don't have a lot of perspective on the detail. Would you explain what makes nanoscience and nanotechnology unique? Speaker 5: Sure, [00:02:00] so nano science is about investigating how the properties of matter change sometimes quite dramatically when we structure them on the nanometers scale, which is really the molecular scale. So in a sense it's quite related to chemistry, but it's about materials and matter and how their behavior is very different than what you'd expect from macroscopic pieces of material. Would you like some examples? [00:02:30] Sure. An example would be great. Okay. A classic example is to look at the optical properties or just the visible appearance of gold and everyone knows, of course, when gold is macroscopic, it's shiny and it's yellowish and we're very used to that form of gold. When you make gold in the form of nanoparticles, the things that are, let's say between five and 50 nanometers across [00:03:00] or containing a few thousand atoms per particle, then the gold no longer looks either yellow or shiny. In fact, you can make stable dispersion or solution of gold at that scale in water. And it appears translucent and red in color. And this effect of Nano scaling and gold has been used to color artistic objects for centuries, but we've only recently become to systematically [00:03:30] understand the science of how these sorts of properties can change so dramatically when we make materials in the nanoscale. Speaker 4: So the actual doing of it has been done for a long time, but the understanding is what's more recent and then the ability to recreate Speaker 5: and the ability to control and deliberately manipulate. Yes. So there are plenty of instances of incidental or almost accidental creation of nanoscale materials and [00:04:00] utilization of these nanoscale effects on properties. But the science of it is about systematically correlating the structure and composition and materials to their properties. And then the nanotechnology or the engineering of of nanoscale materials is about deliberately controlling those properties to create new functional things, objects, devices and so on that we can use for useful things all around us. Speaker 4: And what are some of the common things [00:04:30] that we find nano technology in in our daily lives? Speaker 5: As with any new technology. The first applications are fairly pedestrian in some sense and don't require the most exquisite control over the materials. So one that's quite common is to use metal oxide nanocrystals. Typically things like zinc oxide or titanium oxide in sunblock. These materials absorb UV radiation to [00:05:00] protect our skin from damage from UV. But because they're at the nano scale, instead of looking white, it can be clear. And so it's just that ugly, much more pleasing to put on some block that then appears clear, but still does the job of blocking UV radiation. So this doesn't require a very fine control over the details of the structure or the size of the material. It's only important that the scale of the oxide particles be well below the wavelength [00:05:30] of light, and that's what makes it clear. So it's a very simple use, but nonetheless, very practical and helpful. Speaker 4: What are you finding are the challenges of working with nanoscale material? Speaker 5: It's all about taking that control to the next level. Chemists have learned for a long time how to manipulate atoms and create bonds and put them together into small molecules. Now we're working with structures of [00:06:00] a somewhat larger length scale and wanting to control different aspects of the composition and structure. So there are no ready solutions for deliberately arranging the atoms into let's say a five nanometer crystal with precision, um, in order to generate the properties that you'd like or again, just understand them frankly. So both the creation of materials with precise control and detailed understanding of what their structure is are still very [00:06:30] big challenges. Of course conventional microscopy methods don't extend very well to these small length scales. So there's a need for new characterization approaches. And then as I said, the chemical methods for making molecules and small molecular systems likewise don't necessarily translate to the slightly bigger scale that is nanometer length scale of these materials. Speaker 5: So we need a innovations on all sides, making new materials, new ways to look at them and characterize [00:07:00] them. And then finally the third piece is the theory that helps understand their properties and predict new properties. Again, it's sort of an awkward in between lanes scale where atomic detail matters, but larger scale aspects of how the materials come together matters as well. And that's very difficult to approach with computational methods, so we're seeing the frontier of nanoscience is pushing scientists from all different disciplines to advance their tools and their techniques [00:07:30] in order to really take advantage of what can be done at that landscape. Speaker 4: Okay. Speaker 6: Delia mill iron is our guest. She is the deputy director of the Lawrence Berkeley National Laboratory molecular foundry. She is a chemist working at the nanoscale. You are listening to spectrum on k a l x Berkeley. Speaker 4: You've talked about the meter. Yes. Is that a new form of measurement and how does it relate to anything [00:08:00] else? How do we reflect on an nanometre? Sure, Speaker 5: so it's not a new measure. It's simply a meter times 10 to the minus ninth that's what what Nano means and a more conventional measure on that lane scale might be an Angstrom, which is a traditional measure. It's one order of magnitude smaller than an animator, but to put it in more practical terms, I like to think of the Nano crystals that I work with, for example, which are about five nanometers across, [00:08:30] are about a million times smaller than an ant. So that for me gives me a sort of practical reference point as a chemist. It also makes sense to me to think of a five nanometer crystal as containing about a thousand atoms, but atoms are not necessarily a easy to understand lane skill for everybody. So the the ant is maybe a more common reference point, what natural materials have been created and what about them makes them [00:09:00] more promising than another depending on the realm of properties that you examine. Speaker 5: Promising has all sorts of different meanings, right? So things like semiconductor nano wires or perhaps graphene or carbon nanotubes may be considered promising for new electronic materials because the transport of electrons through these structures can proceed quite unimpeded and move very [00:09:30] readily so that we could have fast electronics or very conductive transparent thin films to replace the things we use today in our flat panel displays and so on. Other nano materials are very promising for diagnostics of different kinds of diseases or even for therapy of different kinds of health issues. So there are biological probes being developed that can be directed into specific areas [00:10:00] of your body. For example, where a tumor site is located using a nanoscale magnet and then they also carry a payload of drugs that can then be released specifically at that site. So you could have targeted therapies. So these sort of multifunctional nano constructs are very interesting. Speaker 5: I would say promising in the long run for for new targeted therapies, I have many fewer side effects than these broad spectrum drugs that we commonly use today. In terms of coming up [00:10:30] with new nanomaterials, is it as often the case that you are trying to create something for a specific purpose or that you accidentally find something that has a characteristic that can be applied pretty widely or to a specific use? I think that much of Nano materials research is motivated by the investigation and discovery of new phenomenon. And I distinguish that from targeted application [00:11:00] focused development because it's often unclear what a new material or it's phenomenological characteristics will actually be useful for. In my lab. Uh, we do tend to think of practical connections, but then the ones that we ultimately realize could be very different from the one that motivated us at the outset of the project. So I think as a scientist it's important to be attuned [00:11:30] for surprising opportunities to apply materials in ways you didn't anticipate. And so you have to be aware of the needs that are out there, the big needs in society, basically paying attention for how the phenomena you're discovering might map onto these societal needs. You probably as a scientist, not going to able to take Speaker 5: a new discovery all the way through to a practical application. But if you don't at [00:12:00] least identify those connections, it will be difficult for engineers and industry to take your discoveries and turn them into practical applications. So there's a role on both sides to make that connection. Speaker 4: [inaudible] you are the deputy director of the molecular foundry at Lawrence Berkeley National Lab. Tell us about the foundry and the work going on there. Speaker 5: So the molecular foundry is a very special place. It's one of five department of energy funded [00:12:30] nanoscale science research centers, which are located around the country. And we have the mission of pushing the forefront of nanoscience broadly defined, so nanoscience in all different aspects while at the same time acting as a user facility to help others in the scientific community, be they academic researchers, industry, others at national labs move the science in their areas forward by leveraging the tools of nanoscience. [00:13:00] So it in effect, it becomes this amazing hub of activity and nanoscience where people from really all around the world are coming to us to leverage capabilities that we are continuously advancing and developing in different kinds of nanoscience be it inorganic nanocrystals, which is my focus theoretical methods for treating nanoscience completely out of this world. In my mind, I'm spectroscopic techniques [00:13:30] for looking at nanostructures.Speaker 5: All these things are being developed at the foundry, at the absolute bleeding edge of nanoscience, and these can have impact in all different areas. And so our users come, they work with us, they learn these state of the art techniques, generate new materials that they can take home with them to their own laboratories, integrate into their materials and processes and devices and so on or do their a specialized characterization on and the amount of science that results by [00:14:00] that multiplication and leveraging is really very exciting to watch. Oh, it's a hub. It's an intersection of ideas in one place of problem, motivations from different perspectives and then it branches right on back out to impact science and in all different ways. Speaker 4: What sort of a funding horizon are you on? Speaker 5: Uh, so we have very stable funding from the Department of Energy. These centers are quite new. They were only established [00:14:30] over the last 10 years. The foundry has been in full operations for about six years and they are very much the flagship capabilities of the office of science within the Department of Energy and will be for quite some time to come. So they're making a very stable and continued investment in this area and continue to see the value and opportunity for really in the end, American economy, taxpayers and industrial [00:15:00] innovation that's generated by all of this scientific activity. Speaker 2: [inaudible]Speaker 4: you were listening to spectrum on k a l x Berkeley, Delia mill, iron of Lawrence Berkeley national lab is talking about her work in nanoscience and nanotechnology. Speaker 2: [inaudible]Speaker 4: what's the focus of your research? Speaker 5: So my research involves the [00:15:30] innovation of Inorganic nanocrystals, which are a few nanometers diameter crystal and arrangements of atoms. And they're using these as building blocks to construct materials. So we put them together with each other and two, for example, porous architectures, or you put them together with polymers or we put them together, uh, with glassy components to construct macroscopic materials often than films. And we're interested [00:16:00] in these primarily for their electrochemical functions. So electric chemical devices are useful for things like batteries, supercapacitors a storing energy also for converting energy. And in our case, we've most recently been focused on electrochromic window applications. So these are function like batteries, but instead of storing charge, they have the effect of changing the tint on a window dynamically as a function [00:16:30] of voltage. But everything starts with the nanocrystals and new ways to put them together with other components to construct materials. Speaker 4: And is the crystal material something unusual or is it real commonplace? Speaker 5: It varies actually. Most of the materials that we craft into nanocrystals are well known and have been studied for a long time in their bulk form. So just as in the example of gold being very different in both and obviously useful for [00:17:00] all sorts of things like currency now having very different function on the Nano scale. We work with materials that maybe are not quite as common places goal, but nonetheless fairly common. So one material we've been working with a lot lately is called indium tin oxide. And whether you know it or not, you probably use it every day. It's the material that provides conductivity in flat panel displays, touch screens, all of these sorts of things. And so in it's normal thin [00:17:30] film form, it's obviously very well established and used around the world for all different applications. It was only synthesized in a well controlled way as Netto crystals in the last few years. Speaker 5: And in the Neto crystal form, it has all of these wonderful properties relating to electric chromic windows. And beyond that it has, I guess I should say more fundamentally, the phenomenology underlying those windows applications is that this [00:18:00] material is plasmonic, which means that it can effectively condense a near infrared light to a very small scale, can amplify the electric field from the light, basically manipulate light in a new way. And people have been doing this with metals like gold as one example. Silver is another for a while, and a whole new field of plasmonics has emerged. Um, now with Ito on the nanoscale, we're bringing [00:18:30] plasmonics into the infrared region of the spectrum, which is going to give us whole news opportunities for manipulation of light of that sword, channeling light and so on. So the, as I was saying earlier, the phenomenology is where we spend the most time and discovery of these plasmonic characteristics of Ito is going to lead to many, many applications. The one we've been focusing on is this electric chromic window idea. Speaker 4: Oh, is this one of the real opportunities [00:19:00] within nano science that when you take a material to the Nano scale, you get all this new behavior [inaudible] Speaker 5: that's the fundamental concept underlying the investigation of nanoscale materials. And so the NNI, the national nanoscience initiative or national nanotechnology initiative, which was started, you know, over a decade ago now had as its founding principle, basically that idea that we would investigate the properties that emerge [00:19:30] when materials are made on the nanoscale that are very distinct from what we see on the macro scale. And from this, uh, we would have a whole new playbook for creating functional materials and devices. Speaker 4: There's been talk about the idea of transparent failure being a good thing in science. So you can learn from what goes wrong. Speaker 5: Yeah, science is full of failure. Most things don't work, especially when you first try them. [00:20:00] So I like to say that in order to be a scientist, you have to be unrelentingly optimistic because you're great idea that you're incredibly excited about, probably won't work or at least it won't work initially. And then you have to try again and try again and try again. And often it won't work even after you've tried again many, many times and you still have to have the same passion for your next great idea that you wake up the next morning [00:20:30] and you're excited to go try something new. That belief in possibility I think is fundamental to science, but at the same point. Yeah, I think you're right. The failures are not merely something to be discarded along the way to, and they do teach us a lot and frankly they suggest the next great idea more often than not. Speaker 5: So we have in mind something we're trying to do and a complete failure to [00:21:00] accomplish that. Whether it's a bond we're trying to make or a way we're trying to control a shape of a material or to create a specific optical property we get something we didn't expect and that should and when science is functioning well does cause you to stop and think about why that's happening. In fact, maybe the challenge, some of the challenge in doing science is not becoming too distracted by all of the [00:21:30] possibilities that emerge. When you do that. It's a mistake of course to be too single minded and focused on an end goal too early because you'll, you'll miss really all the new phenomenon, the things that you least expected are often the most important and innovative, so you have to pay attention to these things and perhaps redefine them as not being failures but rather being a new success or a new seed of a success that can take you in a new direction. Speaker 5: That said, there probably are things that [00:22:00] even in that from that perspective can be viewed as a negative result or a failure and there's an important role. I mean the scientific literature is, is full of every scholarly article has to include a transparent reporting of the conditions that led to what's being defined as success or specific results and a recording of what happens elsewise basically because that allows you to understand much more [00:22:30] deeply where that successful result emerges if you understand the conditions that lead to failure and different types of failure. So definitely for understanding sake, this is essential. Speaker 3: This is the end part. One of our interview with Delia [inaudible] finale, part two will air December 28th at noon. Don't miss it. The molecular foundry website [00:23:00] is foundries.lbl.gov Speaker 1: now the calendar with Lisa [inaudible] and Rick Karnofsky on Saturday, December 15th science at Cow Lecture series. We'll present a free public talk by Rosemary, a Joyce or UC Berkeley anthropology professor on everyday life and science in the Pre-colombian Mayan world. Joyce. We'll discuss how the Maya developed and use their calendar, which spans almost 1200 [00:23:30] years ending around December 21st, 2012 the end of the world, she will explore the observational astronomy made possible through the use of written records, employing one of the only two scripts in the world to develop a sign for zero. The lecture which is free and open to the public, will be held on December 15th from 11 to 12:00 AM in room 100 of the genetics and plant biology building on the UC Berkeley campus. Speaker 7: Tomorrow, December 15th Wild Oakland. [00:24:00] We'll have a free one hour walk from noon to one defined an identifying mushrooms around lake merit. Meet at the Rotary Science Center on the corner of Perkins in Bellevue. The walk will be around the grassy areas, so rattling the boat house and the Lake Merritt Gardens. Learn to read the landscape and find where the mushrooms hide and their role and the local ecology. Bring guidebooks. Have you have them as well as a small pocket knife, a paintbrush [inaudible] jacket. Visit a wild oakland.org for more [00:24:30] info. Speaker 1: On Saturday, December 15th the American Society for Cell Biology welcomes the public to its 2012 keynote lecture. The event will feature Steven Chu Nobel laureate and US Secretary of energy and Arthur Levinson, chair of Genentech and apple here about the future of science and innovation and view an art exhibit by scientists, artists, Graham Johnson and Janet, a Wasa. Attend the art exhibit and reception [00:25:00] from five to five 45 and then stay and listen to the Speakers from six to 7:30 PM free. Preregistration is required at ASC B. Dot. O. R. G, the event takes place at Moscone center west seven 47 Howard street in San Francisco. Saturday, December 15th Speaker 7: the regional parks botanical garden at the intersection of Wildcat Canyon Road and South Park drive and Tilden regional park in the Berkeley hills. [00:25:30] Host the Wayne Rodrick lecture series. These free lectures are on Saturday mornings at 10:30 AM and are on a variety of topics related to plants and natural history. Free Tours of the garden. Begin at 2:00 PM tomorrow's tuck features Dick O'Donnell, who will discuss the floristic surprises and the drought stricken southwest and next Saturday the 22nd of December. Steve Edwards. We'll talk about the botany and GLG of the Lassen region. More information on the series is available@nativeplants.org Speaker 1: [00:26:00] beginning on December 26 the Lawrence Hall of science will begin screening and interactive program in their planetarium called constellations. Tonight. A simple star map will be provided to help participants learn to identify the most prominent constellations of the season in the planetarium. Sky. Questions and activities will be part of the program. The presentation will continue until January 4th and will be held every weekday from two to 2:45 PM [00:26:30] tickets are $4 at the Lawrence Hall of science after the price of admission. Remember that's beginning on December 26th [inaudible] Speaker 7: with two news stories. Here is Rick Karnofsky and Lisa kind of itch. Nature News reported on December 11th Speaker 1: that the u s national ignition facility or Nif at Lawrence Livermore national laboratory is changing directions. Nip uses a 192 ultraviolet laser beams that interact with the gold capsule, creating x-rays. These x-rays [00:27:00] crush a two millimeter target pellet of deuterium and tritium causing fusion. Nif has not yet achieved ignition where it may deliver more energy than it consumes I triple e spectrum criticized the project for being $5 billion over budget and years behind. Schedule in the revised plans [inaudible] scale back to focus on ignition and would devote three years for deciding whether it would be possible. It would increase focus on research, a fusion for the nuclear weapons [00:27:30] stockpile stewardship program and basic science. It would also devote resources to other ignition concepts. Namely polar direct drive on Omega at the University of Rochester and magnetically driven implosions on the San Diego z machine. The Journal. Nature reports that rows matter a natural plant die once price throughout the old world to make fiery red textiles has found a second life as the basis for a new green [00:28:00] battery chemist from the City College of New York teamed with researchers from Rice University and the U S army research lab to develop a nontoxic and sustainable lithium ion battery powered by Perper in a dye extracted from the roots of the matter plant 3,500 years ago. Speaker 1: Civilizations in Asia and the Middle East first boiled matter roots to color fabrics in vivid oranges, reds, and pinks. In its latest incarnation, [00:28:30] the climbing herb could lay the foundation for an ecofriendly alternative to traditional lithium ion batteries. These batteries charge everything from your mobile phone to electric vehicles, but carry with them risks to the environment during production, recycling and disposal. They also pumped 72 kilograms of carbon dioxide into the atmosphere for every kilowatt hour of energy in a lithium ion battery. These grim facts have fed a surging demand to develop green batteries [00:29:00] growing matter or other biomass crops to make batteries which soak up carbon dioxide and eliminate the disposal problem. Speaker 3: The news occurred during the show with his bylaw Astana David from his album folk and acoustic made available through creative Commons license 3.0 attribution. Thank you for listening to spectrum. If you have comments about the show, please send them to us via [00:29:30] our email address is spectrum dot k a l x@yahoo.com join us in two weeks at this same time. [inaudible]. Hosted on Acast. See acast.com/privacy for more information.

Princeton and UC Berkeley trained chemist Delia Milliron is the Deputy Director of the Molecular Foundry at Lawrence Berkeley Lab. In part one, Delia explains Nano Science and Technology. She talks about her research with nanocrystals to make thin films. foundry.lbl.govTranscriptSpeaker 1: Spectrum's next. Speaker 2: Mm mm mm mm mm mm mm Speaker 3: [inaudible].Speaker 1: Welcome [00:00:30] to spectrum the science and technology show on k a l x Berkeley, a biweekly 30 minute program bringing you interviews featuring bay area scientists and technologists as well as a calendar of local events and news. Speaker 4: Good afternoon. My name is Brad Swift. I'm the host of today's show. Today is part one of a two part interview with Delia Mil Iron, the deputy director of the Lawrence Berkeley national lab molecular foundry, [00:01:00] Delia mill iron is a chemist. She received her undergraduate degree from Princeton and her phd from UC Berkeley. Delia leads a research group at the molecular foundry which has recently spun off a startup named heliotrope technologies for group is a partner in the newly announced Joint Center for Energy Storage Research, a multistate department of energy research hub focused on developing transformative new battery technology. Delios group was recently awarded a $3 million grant [00:01:30] by the Department of Energy Advanced Research projects, agency dash energy by e for her work on smart window technologies onto the interview. Delia mill iron. Welcome to spectrum. Speaker 5: Thank you.Speaker 4: I suspect that most of our listeners have heard of nanoscience but don't have a lot of perspective on the detail. Would you explain what makes nanoscience and nanotechnology unique? Speaker 5: Sure, [00:02:00] so nano science is about investigating how the properties of matter change sometimes quite dramatically when we structure them on the nanometers scale, which is really the molecular scale. So in a sense it's quite related to chemistry, but it's about materials and matter and how their behavior is very different than what you'd expect from macroscopic pieces of material. Would you like some examples? [00:02:30] Sure. An example would be great. Okay. A classic example is to look at the optical properties or just the visible appearance of gold and everyone knows, of course, when gold is macroscopic, it's shiny and it's yellowish and we're very used to that form of gold. When you make gold in the form of nanoparticles, the things that are, let's say between five and 50 nanometers across [00:03:00] or containing a few thousand atoms per particle, then the gold no longer looks either yellow or shiny. In fact, you can make stable dispersion or solution of gold at that scale in water. And it appears translucent and red in color. And this effect of Nano scaling and gold has been used to color artistic objects for centuries, but we've only recently become to systematically [00:03:30] understand the science of how these sorts of properties can change so dramatically when we make materials in the nanoscale. Speaker 4: So the actual doing of it has been done for a long time, but the understanding is what's more recent and then the ability to recreate Speaker 5: and the ability to control and deliberately manipulate. Yes. So there are plenty of instances of incidental or almost accidental creation of nanoscale materials and [00:04:00] utilization of these nanoscale effects on properties. But the science of it is about systematically correlating the structure and composition and materials to their properties. And then the nanotechnology or the engineering of of nanoscale materials is about deliberately controlling those properties to create new functional things, objects, devices and so on that we can use for useful things all around us. Speaker 4: And what are some of the common things [00:04:30] that we find nano technology in in our daily lives? Speaker 5: As with any new technology. The first applications are fairly pedestrian in some sense and don't require the most exquisite control over the materials. So one that's quite common is to use metal oxide nanocrystals. Typically things like zinc oxide or titanium oxide in sunblock. These materials absorb UV radiation to [00:05:00] protect our skin from damage from UV. But because they're at the nano scale, instead of looking white, it can be clear. And so it's just that ugly, much more pleasing to put on some block that then appears clear, but still does the job of blocking UV radiation. So this doesn't require a very fine control over the details of the structure or the size of the material. It's only important that the scale of the oxide particles be well below the wavelength [00:05:30] of light, and that's what makes it clear. So it's a very simple use, but nonetheless, very practical and helpful. Speaker 4: What are you finding are the challenges of working with nanoscale material? Speaker 5: It's all about taking that control to the next level. Chemists have learned for a long time how to manipulate atoms and create bonds and put them together into small molecules. Now we're working with structures of [00:06:00] a somewhat larger length scale and wanting to control different aspects of the composition and structure. So there are no ready solutions for deliberately arranging the atoms into let's say a five nanometer crystal with precision, um, in order to generate the properties that you'd like or again, just understand them frankly. So both the creation of materials with precise control and detailed understanding of what their structure is are still very [00:06:30] big challenges. Of course conventional microscopy methods don't extend very well to these small length scales. So there's a need for new characterization approaches. And then as I said, the chemical methods for making molecules and small molecular systems likewise don't necessarily translate to the slightly bigger scale that is nanometer length scale of these materials. Speaker 5: So we need a innovations on all sides, making new materials, new ways to look at them and characterize [00:07:00] them. And then finally the third piece is the theory that helps understand their properties and predict new properties. Again, it's sort of an awkward in between lanes scale where atomic detail matters, but larger scale aspects of how the materials come together matters as well. And that's very difficult to approach with computational methods, so we're seeing the frontier of nanoscience is pushing scientists from all different disciplines to advance their tools and their techniques [00:07:30] in order to really take advantage of what can be done at that landscape. Speaker 4: Okay. Speaker 6: Delia mill iron is our guest. She is the deputy director of the Lawrence Berkeley National Laboratory molecular foundry. She is a chemist working at the nanoscale. You are listening to spectrum on k a l x Berkeley. Speaker 4: You've talked about the meter. Yes. Is that a new form of measurement and how does it relate to anything [00:08:00] else? How do we reflect on an nanometre? Sure, Speaker 5: so it's not a new measure. It's simply a meter times 10 to the minus ninth that's what what Nano means and a more conventional measure on that lane scale might be an Angstrom, which is a traditional measure. It's one order of magnitude smaller than an animator, but to put it in more practical terms, I like to think of the Nano crystals that I work with, for example, which are about five nanometers across, [00:08:30] are about a million times smaller than an ant. So that for me gives me a sort of practical reference point as a chemist. It also makes sense to me to think of a five nanometer crystal as containing about a thousand atoms, but atoms are not necessarily a easy to understand lane skill for everybody. So the the ant is maybe a more common reference point, what natural materials have been created and what about them makes them [00:09:00] more promising than another depending on the realm of properties that you examine. Speaker 5: Promising has all sorts of different meanings, right? So things like semiconductor nano wires or perhaps graphene or carbon nanotubes may be considered promising for new electronic materials because the transport of electrons through these structures can proceed quite unimpeded and move very [00:09:30] readily so that we could have fast electronics or very conductive transparent thin films to replace the things we use today in our flat panel displays and so on. Other nano materials are very promising for diagnostics of different kinds of diseases or even for therapy of different kinds of health issues. So there are biological probes being developed that can be directed into specific areas [00:10:00] of your body. For example, where a tumor site is located using a nanoscale magnet and then they also carry a payload of drugs that can then be released specifically at that site. So you could have targeted therapies. So these sort of multifunctional nano constructs are very interesting. Speaker 5: I would say promising in the long run for for new targeted therapies, I have many fewer side effects than these broad spectrum drugs that we commonly use today. In terms of coming up [00:10:30] with new nanomaterials, is it as often the case that you are trying to create something for a specific purpose or that you accidentally find something that has a characteristic that can be applied pretty widely or to a specific use? I think that much of Nano materials research is motivated by the investigation and discovery of new phenomenon. And I distinguish that from targeted application [00:11:00] focused development because it's often unclear what a new material or it's phenomenological characteristics will actually be useful for. In my lab. Uh, we do tend to think of practical connections, but then the ones that we ultimately realize could be very different from the one that motivated us at the outset of the project. So I think as a scientist it's important to be attuned [00:11:30] for surprising opportunities to apply materials in ways you didn't anticipate. And so you have to be aware of the needs that are out there, the big needs in society, basically paying attention for how the phenomena you're discovering might map onto these societal needs. You probably as a scientist, not going to able to take Speaker 5: a new discovery all the way through to a practical application. But if you don't at [00:12:00] least identify those connections, it will be difficult for engineers and industry to take your discoveries and turn them into practical applications. So there's a role on both sides to make that connection. Speaker 4: [inaudible] you are the deputy director of the molecular foundry at Lawrence Berkeley National Lab. Tell us about the foundry and the work going on there. Speaker 5: So the molecular foundry is a very special place. It's one of five department of energy funded [00:12:30] nanoscale science research centers, which are located around the country. And we have the mission of pushing the forefront of nanoscience broadly defined, so nanoscience in all different aspects while at the same time acting as a user facility to help others in the scientific community, be they academic researchers, industry, others at national labs move the science in their areas forward by leveraging the tools of nanoscience. [00:13:00] So it in effect, it becomes this amazing hub of activity and nanoscience where people from really all around the world are coming to us to leverage capabilities that we are continuously advancing and developing in different kinds of nanoscience be it inorganic nanocrystals, which is my focus theoretical methods for treating nanoscience completely out of this world. In my mind, I'm spectroscopic techniques [00:13:30] for looking at nanostructures.Speaker 5: All these things are being developed at the foundry, at the absolute bleeding edge of nanoscience, and these can have impact in all different areas. And so our users come, they work with us, they learn these state of the art techniques, generate new materials that they can take home with them to their own laboratories, integrate into their materials and processes and devices and so on or do their a specialized characterization on and the amount of science that results by [00:14:00] that multiplication and leveraging is really very exciting to watch. Oh, it's a hub. It's an intersection of ideas in one place of problem, motivations from different perspectives and then it branches right on back out to impact science and in all different ways. Speaker 4: What sort of a funding horizon are you on? Speaker 5: Uh, so we have very stable funding from the Department of Energy. These centers are quite new. They were only established [00:14:30] over the last 10 years. The foundry has been in full operations for about six years and they are very much the flagship capabilities of the office of science within the Department of Energy and will be for quite some time to come. So they're making a very stable and continued investment in this area and continue to see the value and opportunity for really in the end, American economy, taxpayers and industrial [00:15:00] innovation that's generated by all of this scientific activity. Speaker 2: [inaudible]Speaker 4: you were listening to spectrum on k a l x Berkeley, Delia mill, iron of Lawrence Berkeley national lab is talking about her work in nanoscience and nanotechnology. Speaker 2: [inaudible]Speaker 4: what's the focus of your research? Speaker 5: So my research involves the [00:15:30] innovation of Inorganic nanocrystals, which are a few nanometers diameter crystal and arrangements of atoms. And they're using these as building blocks to construct materials. So we put them together with each other and two, for example, porous architectures, or you put them together with polymers or we put them together, uh, with glassy components to construct macroscopic materials often than films. And we're interested [00:16:00] in these primarily for their electrochemical functions. So electric chemical devices are useful for things like batteries, supercapacitors a storing energy also for converting energy. And in our case, we've most recently been focused on electrochromic window applications. So these are function like batteries, but instead of storing charge, they have the effect of changing the tint on a window dynamically as a function [00:16:30] of voltage. But everything starts with the nanocrystals and new ways to put them together with other components to construct materials. Speaker 4: And is the crystal material something unusual or is it real commonplace? Speaker 5: It varies actually. Most of the materials that we craft into nanocrystals are well known and have been studied for a long time in their bulk form. So just as in the example of gold being very different in both and obviously useful for [00:17:00] all sorts of things like currency now having very different function on the Nano scale. We work with materials that maybe are not quite as common places goal, but nonetheless fairly common. So one material we've been working with a lot lately is called indium tin oxide. And whether you know it or not, you probably use it every day. It's the material that provides conductivity in flat panel displays, touch screens, all of these sorts of things. And so in it's normal thin [00:17:30] film form, it's obviously very well established and used around the world for all different applications. It was only synthesized in a well controlled way as Netto crystals in the last few years. Speaker 5: And in the Neto crystal form, it has all of these wonderful properties relating to electric chromic windows. And beyond that it has, I guess I should say more fundamentally, the phenomenology underlying those windows applications is that this [00:18:00] material is plasmonic, which means that it can effectively condense a near infrared light to a very small scale, can amplify the electric field from the light, basically manipulate light in a new way. And people have been doing this with metals like gold as one example. Silver is another for a while, and a whole new field of plasmonics has emerged. Um, now with Ito on the nanoscale, we're bringing [00:18:30] plasmonics into the infrared region of the spectrum, which is going to give us whole news opportunities for manipulation of light of that sword, channeling light and so on. So the, as I was saying earlier, the phenomenology is where we spend the most time and discovery of these plasmonic characteristics of Ito is going to lead to many, many applications. The one we've been focusing on is this electric chromic window idea. Speaker 4: Oh, is this one of the real opportunities [00:19:00] within nano science that when you take a material to the Nano scale, you get all this new behavior [inaudible] Speaker 5: that's the fundamental concept underlying the investigation of nanoscale materials. And so the NNI, the national nanoscience initiative or national nanotechnology initiative, which was started, you know, over a decade ago now had as its founding principle, basically that idea that we would investigate the properties that emerge [00:19:30] when materials are made on the nanoscale that are very distinct from what we see on the macro scale. And from this, uh, we would have a whole new playbook for creating functional materials and devices. Speaker 4: There's been talk about the idea of transparent failure being a good thing in science. So you can learn from what goes wrong. Speaker 5: Yeah, science is full of failure. Most things don't work, especially when you first try them. [00:20:00] So I like to say that in order to be a scientist, you have to be unrelentingly optimistic because you're great idea that you're incredibly excited about, probably won't work or at least it won't work initially. And then you have to try again and try again and try again. And often it won't work even after you've tried again many, many times and you still have to have the same passion for your next great idea that you wake up the next morning [00:20:30] and you're excited to go try something new. That belief in possibility I think is fundamental to science, but at the same point. Yeah, I think you're right. The failures are not merely something to be discarded along the way to, and they do teach us a lot and frankly they suggest the next great idea more often than not. Speaker 5: So we have in mind something we're trying to do and a complete failure to [00:21:00] accomplish that. Whether it's a bond we're trying to make or a way we're trying to control a shape of a material or to create a specific optical property we get something we didn't expect and that should and when science is functioning well does cause you to stop and think about why that's happening. In fact, maybe the challenge, some of the challenge in doing science is not becoming too distracted by all of the [00:21:30] possibilities that emerge. When you do that. It's a mistake of course to be too single minded and focused on an end goal too early because you'll, you'll miss really all the new phenomenon, the things that you least expected are often the most important and innovative, so you have to pay attention to these things and perhaps redefine them as not being failures but rather being a new success or a new seed of a success that can take you in a new direction. Speaker 5: That said, there probably are things that [00:22:00] even in that from that perspective can be viewed as a negative result or a failure and there's an important role. I mean the scientific literature is, is full of every scholarly article has to include a transparent reporting of the conditions that led to what's being defined as success or specific results and a recording of what happens elsewise basically because that allows you to understand much more [00:22:30] deeply where that successful result emerges if you understand the conditions that lead to failure and different types of failure. So definitely for understanding sake, this is essential. Speaker 3: This is the end part. One of our interview with Delia [inaudible] finale, part two will air December 28th at noon. Don't miss it. The molecular foundry website [00:23:00] is foundries.lbl.gov Speaker 1: now the calendar with Lisa [inaudible] and Rick Karnofsky on Saturday, December 15th science at Cow Lecture series. We'll present a free public talk by Rosemary, a Joyce or UC Berkeley anthropology professor on everyday life and science in the Pre-colombian Mayan world. Joyce. We'll discuss how the Maya developed and use their calendar, which spans almost 1200 [00:23:30] years ending around December 21st, 2012 the end of the world, she will explore the observational astronomy made possible through the use of written records, employing one of the only two scripts in the world to develop a sign for zero. The lecture which is free and open to the public, will be held on December 15th from 11 to 12:00 AM in room 100 of the genetics and plant biology building on the UC Berkeley campus. Speaker 7: Tomorrow, December 15th Wild Oakland. [00:24:00] We'll have a free one hour walk from noon to one defined an identifying mushrooms around lake merit. Meet at the Rotary Science Center on the corner of Perkins in Bellevue. The walk will be around the grassy areas, so rattling the boat house and the Lake Merritt Gardens. Learn to read the landscape and find where the mushrooms hide and their role and the local ecology. Bring guidebooks. Have you have them as well as a small pocket knife, a paintbrush [inaudible] jacket. Visit a wild oakland.org for more [00:24:30] info. Speaker 1: On Saturday, December 15th the American Society for Cell Biology welcomes the public to its 2012 keynote lecture. The event will feature Steven Chu Nobel laureate and US Secretary of energy and Arthur Levinson, chair of Genentech and apple here about the future of science and innovation and view an art exhibit by scientists, artists, Graham Johnson and Janet, a Wasa. Attend the art exhibit and reception [00:25:00] from five to five 45 and then stay and listen to the Speakers from six to 7:30 PM free. Preregistration is required at ASC B. Dot. O. R. G, the event takes place at Moscone center west seven 47 Howard street in San Francisco. Saturday, December 15th Speaker 7: the regional parks botanical garden at the intersection of Wildcat Canyon Road and South Park drive and Tilden regional park in the Berkeley hills. [00:25:30] Host the Wayne Rodrick lecture series. These free lectures are on Saturday mornings at 10:30 AM and are on a variety of topics related to plants and natural history. Free Tours of the garden. Begin at 2:00 PM tomorrow's tuck features Dick O'Donnell, who will discuss the floristic surprises and the drought stricken southwest and next Saturday the 22nd of December. Steve Edwards. We'll talk about the botany and GLG of the Lassen region. More information on the series is available@nativeplants.org Speaker 1: [00:26:00] beginning on December 26 the Lawrence Hall of science will begin screening and interactive program in their planetarium called constellations. Tonight. A simple star map will be provided to help participants learn to identify the most prominent constellations of the season in the planetarium. Sky. Questions and activities will be part of the program. The presentation will continue until January 4th and will be held every weekday from two to 2:45 PM [00:26:30] tickets are $4 at the Lawrence Hall of science after the price of admission. Remember that's beginning on December 26th [inaudible] Speaker 7: with two news stories. Here is Rick Karnofsky and Lisa kind of itch. Nature News reported on December 11th Speaker 1: that the u s national ignition facility or Nif at Lawrence Livermore national laboratory is changing directions. Nip uses a 192 ultraviolet laser beams that interact with the gold capsule, creating x-rays. These x-rays [00:27:00] crush a two millimeter target pellet of deuterium and tritium causing fusion. Nif has not yet achieved ignition where it may deliver more energy than it consumes I triple e spectrum criticized the project for being $5 billion over budget and years behind. Schedule in the revised plans [inaudible] scale back to focus on ignition and would devote three years for deciding whether it would be possible. It would increase focus on research, a fusion for the nuclear weapons [00:27:30] stockpile stewardship program and basic science. It would also devote resources to other ignition concepts. Namely polar direct drive on Omega at the University of Rochester and magnetically driven implosions on the San Diego z machine. The Journal. Nature reports that rows matter a natural plant die once price throughout the old world to make fiery red textiles has found a second life as the basis for a new green [00:28:00] battery chemist from the City College of New York teamed with researchers from Rice University and the U S army research lab to develop a nontoxic and sustainable lithium ion battery powered by Perper in a dye extracted from the roots of the matter plant 3,500 years ago. Speaker 1: Civilizations in Asia and the Middle East first boiled matter roots to color fabrics in vivid oranges, reds, and pinks. In its latest incarnation, [00:28:30] the climbing herb could lay the foundation for an ecofriendly alternative to traditional lithium ion batteries. These batteries charge everything from your mobile phone to electric vehicles, but carry with them risks to the environment during production, recycling and disposal. They also pumped 72 kilograms of carbon dioxide into the atmosphere for every kilowatt hour of energy in a lithium ion battery. These grim facts have fed a surging demand to develop green batteries [00:29:00] growing matter or other biomass crops to make batteries which soak up carbon dioxide and eliminate the disposal problem. Speaker 3: The news occurred during the show with his bylaw Astana David from his album folk and acoustic made available through creative Commons license 3.0 attribution. Thank you for listening to spectrum. If you have comments about the show, please send them to us via [00:29:30] our email address is spectrum dot k a l x@yahoo.com join us in two weeks at this same time. [inaudible]. See acast.com/privacy for privacy and opt-out information.

With this week's episode The Savages being obsessed with their light guns, English Gav takes a look at what light is and its history in science. Links DTT 3.09 - Drunken Science (alternate mp3 download) Cover: NASA/Goddard Space Flight Center This video takes SDO images and applies additional processing to enhance the structures visible. While there is no scientific value to this processing, it does result in a beautiful, new way of looking at the sun. The original frames are in the 171 Angstrom wavelength of extreme ultraviolet. This wavelength shows plasma in the solar atmosphere, called the corona, that is around 600,000 Kelvin. The loops represent plasma held in place by magnetic fields. They are concentrated in "active regions" where the magnetic fields are the strongest. These active regions usually appear in visible light as sunspots. The events in this video represent 24 hours of activity on September 25, 2011.

Embedded Linux Conference Europe (ELC-E) 2012 wrapped up last week in Barcelona. By far, the most popular embedded platform of choice for demonstrations was BeagleBone. Here are four examples that include links to the slides taken from the eLinux wiki ELC-E presentation page. Videos of the presentations should be available from Free Electrons soon.Matt Ranostay opened up the presentations with "Beaglebone: The Perfect Telemetry Platform?" where he explored various telemetry applications such as weather stations, radiation monitors, earthquake detection mesh networks, home security systems and entropy pool generation. He discussed sharing data with tools like COSM and the hardware and software he developed for his own Geiger Cape plug-in board. Alan Ott of Signal 11 Software followed up with an excellent overview of "Wireless Networking with IEEE 802.15.4 and 6LoWPAN". Alan discussed the power consumption of various wireless communications technologies, security and much more, including what is supported in Linux. Alan wrapped up with a demo using BeagleBone and an ultrasonic range finder. Dave Anders snapped a picture of the Altoids-tin encased demo. Matt Porter of Texas Instruments stepped away from sensors and controls bringing back the Commodore 64 demoscene with "What's Old Is New: A 6502-based Remote Processor". While this might seem like a bit of a throw-back, many modern issues and solutions were explored to give us this taste of the past, including the Linux remoteproc/virtio interfaces to remote processors, the AM335x PRUSS processor that is extremely adept at bit-banging and the Fritzing design tool.  Matt has also shared a picture of his wiring handy-work.Finally, Koen Kooi of CircuitCo presented on one of the fundamental BeagleBone challenges, "Supporting 200 Different Expansionboards: The Broken Promise of Devicetree". If you frequent #beagle, you probably already know that Koen isn't easy to please and so the title shouldn't be much of a surprise. You might then be surprised to note on the first slide where "broken" has been scratched out! We certainly aren't there yet, but the device tree maintainers and AM335x kernel developers are starting to address the unique opportunities around BeagleBone cape expansion boards in the mainline Linux kernel, making a reality out of the dream of supporting hundreds of boards with a single kernel distributed ahead of the add-ons!The continued enthusiasm of the embedded Linux community is just one element of what makes BeagleBoard.org successful, but it probably makes me happier than any other. With many of these developers moving the state of the Linux kernel ahead and even looking at sharing their hardware ideas in the BeagleBone Cape Plug-in Board Design Contest, I see a bright future where the largest collaborative software project of all time fully embraces the hardware and maker communities such that we can build a world where individuals and even children can reproduce electronics and computers down to the circuit level, not simply build on black magic.

Today we interview Greg Kroah-Hartman and your hosts are Jason Kridner and Jeffery Osier-Mixon. Gerald will be back in two weeks.To provide questions or suggestions:Call +1-713-234-0535 orvisit the BeagleCast suggestions formLinks to the recordingsBeagleCast-20110325.mp3BeagleCast-20110325.oggLinks to show topicsSome in stock @ Digi-Key this week!    A 300ms BeagleBoard boot?    Using git submodule and busybox to track mainline developmentAnnouncing the Level One eXpansion (LOX) Board    BeagleBoard at Embedded Linux Conference (CATCAN, Gumstix Stagecoach, SuperJumbo, Avnet, and WLAN hacking)    Always Innovating talk at the 2011 Embedded Linux Conference     Sandia cluster of 49 OMAP3s    TI introduces OpenLink    Processing and Processing-JS on the BeagleBoard under Angstrom    BeagleBoard based oscilloscope using JavaScript and Processing.JS     Arduino IDE and upload with avrdude to Trainerboard (AVRISP2)    Processing on Beagleboard xM    Making Processing/Arduino IDE/ReplicaorG work on ARM     Android Oscilloscope on the Beagleboard xM using Rowboat    Upcoming eventsMaker Faire Bay Area, May 21-22, 2011ESC Chicago, June 6-8, 2011Stompbox Design Summer Workshop at Stanford University, July 18-July 22, 2011     The Greg K-H interview is roughly the last 15 minutes.

The theme of today's show is "Super Jumbo" and your hosts are Jason Kridner, Gerald Coley and Jeffery Osier-Mixon.To provide questions or suggestions:Call +1-713-234-0535 orvisit the BeagleCast suggestions formLinks to the recordingsBeagleCast-20110325.mp3BeagleCast-20110325.oggHeadline newsWindows Compact 7 Two new Distributors in China -- ChipSee -- CATCAN From the RSS feed FFmpeg fork becomes libav Clojure on The Beagleboard -- What is a closure vs. what is Clojure?The 2.6.38 kernel is out What Is CLFS? - File System - Check! OpenEmbedded at CeBIT 2011 -- Should we still be excited about CES and CeBIT? Face chasing BeagleBoard-based robot using a Kinect How to build QT Framework 4.7.2 and OpenCV 2.2 for Beagleboard-xM -- How to build sample program for capturing image from camera (OpenCV and Qt) SPI with Trainer-xM Running CyanogenMod on BeagleBoard -- What is CyanogenMod? -- What is Rowboat?NEWS IGEPv2 goes Open Hardware Open Hardware Summit date announced for 2011? -- Looking for votes on a logoBeagleboard: Power usage (current draw) for certain scenarios Upcoming events Indiana Linuxfest OpenSource COM BOF/LUG Mumbai Meeting, 26th March 2011 Community activityGSoC Update -- BeagleBoard.org not a mentoring organization this year -- Still looking for mentors to volunteer to mentor in other projects -- Considering a smaller scale BeagleBoard Summer of Code Always Innovating Announcement...Super Jumbo Beagle Buffet! Upcoming Khasim Syed Mohammed will be on next week to discuss the Android Rowboat project

Today's hosts are Jason Kridner, Gerald Coley and Jeffery Osier-Mixon.  Below are the show note links. Links to the recordingsBeagleCast-20110314.mp3BeagleCast-20110314.oggTo provide questions or suggestions:Call +1-713-234-0535 orvisit the BeagleCast suggestions formFrom the RSS feed Running a BeagleBoard off of Batteries    BeagleBoard cases with a MakerBot on ThingiverseNew SGX Graphics Driver Release 4.03.00.02 for Linux now available!    DVI-D to VGA converter for BeagleBoard-xM and issue to be fixed with the current BeagleBoardToys VGA adapter when using a BeagleBoard-xM   Kinect + BeagleBoard-xM (now need GLES)     Leverett and Wasson Win Texas Instruments Beagle Board Design Challenge    Toolchain, Check! Kernel, Check! - Cross Linux From Scratch Twitter badge on the blog pageLots of interesting #BeagleBoard tweetsFollow the #BeagleBoard RSS feed news items on Twitter  Upcoming eventsTweet @Jadon for free BeagleBoard hands-on training on March 26th at Indiana Linuxfest going on March 25-27Linux Collaboration Summit on April 6-8 Embedded Linux Conference on April 11-13Maker Faire Bay Area on May 21-22BeagleBoard-xM Rev C HW and SW UpdateNew release candidate from AngstromFAT vs. ext2boot.scr vs uEnv.txt change is not welcomed by all Why won't old MLO and u-boot work with xM rev C?Hot Topics on the BeagleBoard Google GroupMark Yoder's ECE497 class with some students using the KinectCollecting Google Summer of Code project ideas such as the car PC projectFuture topics and guestsThe theme music for BeagleCast was created and provided by Alasdair Drake.

Today's hosts are Jason Kridner, Gerald Coley and Jeffery Osier-Mixon.  Below are the show note links. Links to the recordingsBeagleCast-20110307.mp3BeagleCast-20110307.oggTo provide questions or suggestions:Call +1-713-234-0535 orvisit the BeagleCast suggestions formJeff and Yocto    Jeff at a conference near the Columbia river gorge    Jeff now the Yocto community manager    Yocto includes Poky build tools, is multiplatform and has a BeagleBoard BSP    Yocto gets many new partners    What does it mean to join with OpenEmbedded?   OE and Gentoo share rootsArago Project    Koen working on the oe-core  eLinux wiki summary of embedded Linux projects    Wikis "are like bread" (good when fresh)    BeagleBoard.org and Google Summer of Code    oe-core status update and Yocto birds of a feather at ELC week of April 10SD card discussion    Amazon selling consumer friendly packaging   SD card performance shootout needed to measure controller performance    BeagleBoard and electronics hobbyists of all agesMaker Faire Getting Started in ElectronicsCapacitors explode 555 timer contest News from the BeagleBoard.org RSS feed and elsewhereCloud9 IDE on BeagleBoardBeagleBoard Trainer-xMContributing upstream patches, such as uEnv.txt patch in u-bootThe move from ttyS2 to ttyO2linux-omap kernel patchworkLinaro statusLinux newsLinux input events in PerlStudent Robotics has a nice BeagleBoard based robot design and real student roots xM now available from Tenet Technetronics Koen made BeagleBoard coasters with his MakerBotAdobe Flash10.1 with DSP H264PIXHAWK Gumstix CameraBeagleWall with interview of Roger MonkThe theme music for BeagleCast was created and provided by Alasdair Drake.

Dr Hoffmann @ Blind Spot - 25th December 2010 8pm 1, Samuli Kemppi – Dark Matter / Mote Evolver 2, Robert Hood – Alpha / M-Plant 3, Frank Martiniq – Blast Corps / Stroboscopic Artefacts 4, Marcel Fengler – Thwack / Mote Evolver 5, Chris Liebing & Tommy Four Seven – Bauhaus (Mallet Mix) / Bauhaus 6, Xhin – Blade Moth (Tool) / Meerestief 7, Pfirter – The Dub Track (Brian Sanhaji Remix) / Driving Forces Recordings 8, M0H – Se7en / Touched 9, Sasha Carassi – Rowbells / Weave 10, Angstrom, Aalberg – Cockroach (Pfirter Remix) / Girafe Sauvage 11, Speedy J – Trails (Edit Select Remix) / Electric Deluxe 12, Speedy J - Edlx Tool (Chris Liebing Edit) / CLR 13, Mark Broom – She Don't Like The Collar / Edit Select 14, James Ruskin & Mark Broom – Hostage / Blueprint 15, Joseph Capriati – Pasworld (Mono Tool) 16, Planetary Assault System – Temporary Suspension / Ostgut Ton 17, Terence Fixmer – Electric City (Speedy J Tool) / Electric Deluxe 18, A.Paul – Option / M_Rec Ltd 19, Logotech – Blind (Morgan Tomas Repaint) / Naked Lunch 20, Speedy J – Armstrong / CLR Kalden Bess aka m0h @ Blind Spot - 25th December 2010 8.50pm 01, Alex Smoke, Edit Select - The Retainer (Original Mix) / Slant Records 02, Hans Bouffmyhre - Subterfuge (Original Mix) / Perc Trax 03, Nir Shoshani - Awake Me (Original Mix) / Punch Music 04, Psyk - Throes (Original Mix) / Figure 05, Kalden Bess (Aka M0h) - Last Day (Original Mix) / Respekt 06, Mutant Clan - Arcadia (Original Mix) / Balance Music 07, Klement Bonelli, Linan's - Give You Sometin (Santos Woodo Jack Remix) / Krome 08, Gary Beck - Yes! / Bek Audio 09, Kalden Bess (Aka M0h) - Funktion One (Original Mix) / Punch Music 10, Kalden Bess (Aka M0h) - Faceless (Original Mix) / Prosthetic Pressings 11, Masuki - Vix 3 (Len Faki Edit) / Prosthetic Pressings 12, Egor Boss - Shades Of The Night (Kalden Bess Remix) / Indek 13, Kalden Bess (Aka M0h) & Kimono - Face Your Destroyer (Original Mix) / Ground Factory Records This show is syndicated & distributed exclusively by Syndicast. If you are a radio station interested in airing the show or would like to distribute your podcast / radio show please register here: https://syndicast.co.uk/distribution/registration

Blind Spot Radio Show 084 | Kalden Bess (aka m0h) & Dr HoffmannnnDr Hoffmann @ Blind Spot - 25th December 2010 8pm 1, Samuli Kemppi – Dark Matter / Mote Evolver 2, Robert Hood – Alpha / M-Plant 3, Frank Martiniq – Blast Corps / Stroboscopic Artefacts 4, Marcel Fengler – Thwack / Mote Evolver 5, Chris Liebing & Tommy Four Seven – Bauhaus (Mallet Mix) / Bauhaus 6, Xhin – Blade Moth (Tool) / Meerestief 7, Pfirter – The Dub Track (Brian Sanhaji Remix) / Driving Forces Recordings 8, M0H – Se7en / Touched 9, Sasha Carassi – Rowbells / Weave 10, Angstrom, Aalberg – Cockroach (Pfirter Remix) / Girafe Sauvage 11, Speedy J – Trails (Edit Select Remix) / Electric Deluxe 12, Speedy J - Edlx Tool (Chris Liebing Edit) / CLR 13, Mark Broom – She Don’t Like The Collar / Edit Select 14, James Ruskin & Mark Broom – Hostage / Blueprint 15, Joseph Capriati – Pasworld (Mono Tool) 16, Planetary Assault System – Temporary Suspension / Ostgut Ton 17, Terence Fixmer – Electric City (Speedy J Tool) / Electric Deluxe 18, A.Paul – Option / M_Rec Ltd 19, Logotech – Blind (Morgan Tomas Repaint) / Naked Lunch 20, Speedy J – Armstrong / CLR Kalden Bess aka m0h @ Blind Spot - 25th December 2010 8.50pm 01, Alex Smoke, Edit Select - The Retainer (Original Mix) / Slant Records 02, Hans Bouffmyhre - Subterfuge (Original Mix) / Perc Trax 03, Nir Shoshani - Awake Me (Original Mix) / Punch Music 04, Psyk - Throes (Original Mix) / Figure 05, Kalden Bess (Aka M0h) - Last Day (Original Mix) / Respekt 06, Mutant Clan - Arcadia (Original Mix) / Balance Music 07, Klement Bonelli, Linan's - Give You Sometin (Santos Woodo Jack Remix) / Krome 08, Gary Beck - Yes! / Bek Audio 09, Kalden Bess (Aka M0h) - Funktion One (Original Mix) / Punch Music 10, Kalden Bess (Aka M0h) - Faceless (Original Mix) / Prosthetic Pressings 11, Masuki - Vix 3 (Len Faki Edit) / Prosthetic Pressings 12, Egor Boss - Shades Of The Night (Kalden Bess Remix) / Indek 13, Kalden Bess (Aka M0h) & Kimono - Face Your Destroyer (Original Mix) / Ground Factory Records

Dr Hoffmann @ Blind Spot – 26th June 2010 8pm 1, Samuli Kemppi – Dark Matter /Mote Evolver/ 2, Robert Hood – Alpha /M-Plant/ 3, Frank Martiniq – Blast Corps /Stroboscopic Artefacts/ 4, Marcel Fengler – Thwack /Mote Evolver/ 5, Chris Liebing & Tommy Four Seven – Bauhaus (Mallet Mix) /Bauhaus/ 6, Xhin – Blade Moth (Tool) /Meerestief/ 7, Pfirter – The Dub Track (Brian Sanhaji Remix) /Driving Forces Recordings/ 8, M0H – Se7en /Touched/ 9, Sasha Carassi – Rowbells /Weave/ 10, Angstrom, Aalberg – Cockroach (Pfirter Remix) /Girafe Sauvage/ 11, Speedy J – Trails (Edit Select Remix) /Electric Deluxe/ 12, Speedy J - Edlx Tool (Chris Liebing Edit) /CLR/ 13, Mark Broom – She Don't Like The Collar /Edit Select/ 14, James Ruskin & Mark Broom – Hostage /Blueprint/ 15, Joseph Capriati – Pasworld (Mono Tool) 16, Planetary Assault System – Temporary Suspension /Ostgut Ton/ 17, Terence Fixmer – Electric City (Speedy J Tool) /Electric Deluxe/ 18, A.Paul - Option 19, Logotech – Blind (Morgan Tomas Repaint) /Naked Lunch/ 20, Speedy J – Armstrong /CLR/ Space Djz @ Blind Spot – 26th June 2010 8.55pm 1, Moritz Von Oswald - Movement 4 /Recompose/ 2, Flug – Factor AG (Pfirter Remix) /Sleaze/ 3, Alexx Wolfe - Metaphor /Monocline Records/ 4, Chris Hope & Andre Walter – Otum 288 /Driving Forces Recording/ 5, Samuel L Session - Inner City Dust /Figure/ 6, Andy White - Stereophony /SWR/ 7, Speedy J - Armstrong /CLR/ 8, Adam Beyer - Antistius /CLR/ 9, Flawer & Nick Borsato - Age Of Bricks ( Audio Injection Remix) /Impact Mechanics/ 10, Reset Robot - V3 /Sprout/ 11, Jamie Anderson & Mr. K-Alexi - Cyclone /MIJA/ 12, Andy White - Crash /SWR/ 13, Tex-Rec - Detonator /SWR/ 14, Jamie Bissmire & Kyle Geiger - Lucky Numbers (Submerge Remix) /Driving Forces Recordings/ 15, Ben Sims - Hypnosis /DrumCode/ 16, Vladimir Acic - Red Planet /1605/ 17, Pfirter – Mi Estudio /CLR/ 18, Audio Injection - Why I Am /Droid/ 19, Tommy Four Seven - Surma (Speedy J Dub Tool) /Electric Deluxe/ 20, Kill Minimal - Nuevos Aires (Gabriel D'or & Bordoy Remix) /Selected/ 21, A.Mochi - White Out /Figure/ 22, Alex D'Elia & Nihil Young - Low End Theory /1605/ This show is syndicated & distributed exclusively by Syndicast. If you are a radio station interested in airing the show or would like to distribute your podcast / radio show please register here: https://syndicast.co.uk/distribution/registration

Blind Spot Radio Show 060 | Space Djz & Dr HoffmannnnDr Hoffmann @ Blind Spot – 26th June 2010 8pm 1, Samuli Kemppi – Dark Matter /Mote Evolver/ 2, Robert Hood – Alpha /M-Plant/ 3, Frank Martiniq – Blast Corps /Stroboscopic Artefacts/ 4, Marcel Fengler – Thwack /Mote Evolver/ 5, Chris Liebing & Tommy Four Seven – Bauhaus (Mallet Mix) /Bauhaus/ 6, Xhin – Blade Moth (Tool) /Meerestief/ 7, Pfirter – The Dub Track (Brian Sanhaji Remix) /Driving Forces Recordings/ 8, M0H – Se7en /Touched/ 9, Sasha Carassi – Rowbells /Weave/ 10, Angstrom, Aalberg – Cockroach (Pfirter Remix) /Girafe Sauvage/ 11, Speedy J – Trails (Edit Select Remix) /Electric Deluxe/ 12, Speedy J - Edlx Tool (Chris Liebing Edit) /CLR/ 13, Mark Broom – She Don’t Like The Collar /Edit Select/ 14, James Ruskin & Mark Broom – Hostage /Blueprint/ 15, Joseph Capriati – Pasworld (Mono Tool) 16, Planetary Assault System – Temporary Suspension /Ostgut Ton/ 17, Terence Fixmer – Electric City (Speedy J Tool) /Electric Deluxe/ 18, A.Paul - Option 19, Logotech – Blind (Morgan Tomas Repaint) /Naked Lunch/ 20, Speedy J – Armstrong /CLR/ Space Djz @ Blind Spot – 26th June 2010 8.55pm 1, Moritz Von Oswald - Movement 4 /Recompose/ 2, Flug – Factor AG (Pfirter Remix) /Sleaze/ 3, Alexx Wolfe - Metaphor /Monocline Records/ 4, Chris Hope & Andre Walter – Otum 288 /Driving Forces Recording/ 5, Samuel L Session - Inner City Dust /Figure/ 6, Andy White - Stereophony /SWR/ 7, Speedy J - Armstrong /CLR/ 8, Adam Beyer - Antistius /CLR/ 9, Flawer & Nick Borsato - Age Of Bricks ( Audio Injection Remix) /Impact Mechanics/ 10, Reset Robot - V3 /Sprout/ 11, Jamie Anderson & Mr. K-Alexi - Cyclone /MIJA/ 12, Andy White - Crash /SWR/ 13, Tex-Rec - Detonator /SWR/ 14, Jamie Bissmire & Kyle Geiger - Lucky Numbers (Submerge Remix) /Driving Forces Recordings/ 15, Ben Sims - Hypnosis /DrumCode/ 16, Vladimir Acic - Red Planet /1605/ 17, Pfirter – Mi Estudio /CLR/ 18, Audio Injection - Why I Am /Droid/ 19, Tommy Four Seven - Surma (Speedy J Dub Tool) /Electric Deluxe/ 20, Kill Minimal - Nuevos Aires (Gabriel D'or & Bordoy Remix) /Selected/ 21, A.Mochi - White Out /Figure/ 22, Alex D'Elia & Nihil Young - Low End Theory /1605/

Dr Hoffmann @ Blind Spot 3rd April 2010 8pm 1, Steve Parker – Klik Klog – Sci+Tec 2, Citizen Kain, Phuture Traxx – Libido – Neverending Records 3, Knobs – Burundi – Clonk Records 4, Xhin – Plexus – Meerestief 5, Flug – Old School Chords – Rubber Band 6, Dyno – Risvegli – Hell Yeah 7, Tiga – Overtime (Adam Beyer & Jesper Dahlbäck Dub Mix) - Turbo 8, Robert Hood – Alpha – M-Plant 9, Samuli Kemppi – Dark Matter – Mote Evolver 10, Shlomi Aber – Groove Mechanism – Ovum Recordings 11, Sian – Qubliette – Octopus 12, Pfirter – The Dub Track (Brian Sanhaji Remix) – Driving Forces Recordings 13, Rafa Siles – Con Un Canto En Los Dientes (Remute Remix) - Remute 14, Angstrom, Aalberg – Cockroach (Pfirter Remix) – Giraffe Sauvage Acid Circus @ Blind Spot 3rd April 2010 9pm 1, Sound Vandals - On Your Way - Nu Groove Recordings 2, Photek - Glamourama - Science Recordings 3, Ben Klock - Goodly Sin (Rob Hood Remix) - Ostgut Ton 4, Acid Circus - Sweep Play - Unreleased 5, Tim Xavier / Par Grindvik - Subtle Paradise - Ltd4000 6, Shlomi Aber - Groove Mechanism - Ovum Recordings 7, Mark Broom / Dustin Zahn - Leave Me Alone (Drumcell Remix) - Enemy Recordings 8, Acid Circus - New Hoodies - Unreleased 9, Mark Broom / James Ruskin - Hostage - Blueprint 10, Roman Flugel Presents Solyent Green - La Forza Del Destino (Radio Slave Remix) - Playhouse 11, A.Paul - Earthlings Ep - M_Rec Ltd 03 12, Silent Servant - Demonstration - Sandwell District 13, Dead Beat - Vampire - Echochord 14, Levon Vincent - Solemn Days - Deconstruct Music 15, Function / Jerome Sydenham - Two Ninety One - CLR 16, Harry Axt - Bombaz - Supdub Recordings 17, Raiz - Raiz - Historia + Violencia 18, Acid Circus - Professionals - Unreleased 19, Acid Circus - Hit Me Up - Unreleased 20, Telefon Tel Aviv - Immolate Yourself (Ben Klock Jack Mix) - Bpitch Control 21, Audio Injection - Ive Fallen Raw Mix - Droid Recordings 22, Nagen & Saugen - Deep Throat - Hörspielmusik 23, Chris Liebing - Auf Und Davon - CLR 24, Acid Circus - H Head - Unreleased 25, Slam - Positive Education (Derrick Carter Remix) - Soma Recordings 26, Jaime Anderson Feat. K Alexi Shelby - Cyclone (Vocal Mix) - Mija Recordings 27, Marc Ashken - The Second Mouse (Donk Boys Remix) - Fvf Records 28. gideon- freak your body - gringo recordings 29. clint foster - process - geometric This show is syndicated & distributed exclusively by Syndicast. If you are a radio station interested in airing the show or would like to distribute your podcast / radio show please register here: https://syndicast.co.uk/distribution/registration

Blind Spot Radio Show 049 | Acid Circus & Dr HoffmannnnDr Hoffmann @ Blind Spot 3rd April 2010 8pm 1, Steve Parker – Klik Klog – Sci+Tec 2, Citizen Kain, Phuture Traxx – Libido – Neverending Records 3, Knobs – Burundi – Clonk Records 4, Xhin – Plexus – Meerestief 5, Flug – Old School Chords – Rubber Band 6, Dyno – Risvegli – Hell Yeah 7, Tiga – Overtime (Adam Beyer & Jesper Dahlbäck Dub Mix) - Turbo 8, Robert Hood – Alpha – M-Plant 9, Samuli Kemppi – Dark Matter – Mote Evolver 10, Shlomi Aber – Groove Mechanism – Ovum Recordings 11, Sian – Qubliette – Octopus 12, Pfirter – The Dub Track (Brian Sanhaji Remix) – Driving Forces Recordings 13, Rafa Siles – Con Un Canto En Los Dientes (Remute Remix) - Remute 14, Angstrom, Aalberg – Cockroach (Pfirter Remix) – Giraffe Sauvage Acid Circus @ Blind Spot 3rd April 2010 9pm 1, Sound Vandals - On Your Way - Nu Groove Recordings 2, Photek - Glamourama - Science Recordings 3, Ben Klock - Goodly Sin (Rob Hood Remix) - Ostgut Ton 4, Acid Circus - Sweep Play - Unreleased 5, Tim Xavier / Par Grindvik - Subtle Paradise - Ltd4000 6, Shlomi Aber - Groove Mechanism - Ovum Recordings 7, Mark Broom / Dustin Zahn - Leave Me Alone (Drumcell Remix) - Enemy Recordings 8, Acid Circus - New Hoodies - Unreleased 9, Mark Broom / James Ruskin - Hostage - Blueprint 10, Roman Flugel Presents Solyent Green - La Forza Del Destino (Radio Slave Remix) - Playhouse 11, A.Paul - Earthlings Ep - M_Rec Ltd 03 12, Silent Servant - Demonstration - Sandwell District 13, Dead Beat - Vampire - Echochord 14, Levon Vincent - Solemn Days - Deconstruct Music 15, Function / Jerome Sydenham - Two Ninety One - CLR 16, Harry Axt - Bombaz - Supdub Recordings 17, Raiz - Raiz - Historia + Violencia 18, Acid Circus - Professionals - Unreleased 19, Acid Circus - Hit Me Up - Unreleased 20, Telefon Tel Aviv - Immolate Yourself (Ben Klock Jack Mix) - Bpitch Control 21, Audio Injection - Ive Fallen Raw Mix - Droid Recordings 22, Nagen & Saugen - Deep Throat - Hörspielmusik 23, Chris Liebing - Auf Und Davon - CLR 24, Acid Circus - H Head - Unreleased 25, Slam - Positive Education (Derrick Carter Remix) - Soma Recordings 26, Jaime Anderson Feat. K Alexi Shelby - Cyclone (Vocal Mix) - Mija Recordings 27, Marc Ashken - The Second Mouse (Donk Boys Remix) - Fvf Records 28. gideon- freak your body - gringo recordings 29. clint foster - process - geometric

BeagleBoard.org has been listed as one of the accepted mentoring organizations for the Google Summer of Code 2010!!!Over 365 organizations applied and we are among the 150 lucky Free and Open Source projects that were accepted. About 1,000 students are expected to have their project proposals accepted and Google will be providing US$5,000 to every student and US$500 to the mentoring organization for every successfully completed project. Texas Instruments will be providing BeagleBoard hardware through the BeagleBoard.org Sponsored Projects Program. TinCanTools has offered to provide Zippy boards to students using those in their projects.Now is the time for mentors (people who would like to assist the students), to sign up on the GSoC2010 site and to update the ideas list. It is also the time for students to get familiar with the BeagleBoard.org project and community before applications begin being accepted on March 29, so be sure to hang out on the #gsoc and #beagle channels on irc.freenode.net.Spread the good news and bring on the projects!!!

1.Jeison Torres - I Heard Her Groove (Felipe Abel Remix) 2.Angstrom, Aalberg - Hornet (Igor Krsmanovic Remix) 3.David Herrero - Monkey Island (Original Mix) 4.Alan Prosser, Dean Laidler - Underground Illusion (Original Mix) 5.Johan Dresser - Fire In The Sky (Original Mix) 6.Lain Christoph, DJ Lex - Desert Night (Original Mix) 7.J. Velarde, Pombo, Luque - Club Sounds (Original Mix) 8.Micha Moor - Learn To Fly (Mario Da Ragnio Remix) 9. ft Loridana Majori - No More Lies (Dennis Christopher Dub) 10.S Flint - Alone With You (Original Mix) 11.StoneBridge & DaYeene - The Morning After (R Rivera Juicy Instrumental)

1.Jeison Torres - I Heard Her Groove (Felipe Abel Remix) 2.Angstrom, Aalberg - Hornet (Igor Krsmanovic Remix) 3.David Herrero - Monkey Island (Original Mix) 4.Alan Prosser, Dean Laidler - Underground Illusion (Original Mix) 5.Johan Dresser - Fire In The Sky (Original Mix) 6.Lain Christoph, DJ Lex - Desert Night (Original Mix) 7.J. Velarde, Pombo, Luque - Club Sounds (Original Mix) 8.Micha Moor - Learn To Fly (Mario Da Ragnio Remix) 9. ft Loridana Majori - No More Lies (Dennis Christopher Dub) 10.S Flint - Alone With You (Original Mix) 11.StoneBridge & DaYeene - The Morning After (R Rivera Juicy Instrumental)