Podcasts about Indole

Jeremías 33:6 “He aquí que yo les traeré sanidad y medicina; y los curaré, y les revelaré abundancia de paz y de verdad”.¿Qué es el corazón? Abarca la voluntad, el asiento de los afectos y de los deseos, es el Lugar Santísimo en el hombre, la cámara secreta del Espíritu. Bíblicamente hablando, el corazón es el asiento de las actitudes, emociones y de la inteligencia. Se refiere a la mente, los pensamientos, los sentimientos y al intelecto en general, es el centro mismo del ser humano, es el centro de la personalidad y por ende este determina nuestra manera de ser, lo que guarda el corazón influye nuestros pensamientos y nuestros comportamientos, Proverbios 23:7 “Porque cual es su pensamiento en su corazón, tal es él”, por tal razón hay que guardarlo, cuidarlo, protegerlo, Proverbios 4:23 “Sobre toda cosa guardada, guarda tu corazón; Porque de él mana la vida”.El corazón es el centro donde convergen las áreas más importantes de nuestra vida: la física, emocional, espiritual y económica. Cuando estas áreas han sido heridas o afectadas por el pecado, la maldad o la violencia, el corazón se contamina. Esta contaminación interna no solo afecta nuestra salud y bienestar, sino que también se manifiesta en forma de temores, angustias, enfermedades, conflictos, escasez, destrucción, separación y violencia. En otras palabras, un corazón dañado inevitablemente influye en todo nuestro entorno y forma de vivir.El corazón del hombre esta ligado al carácter, Jesús lo enseñó en Lucas 6:45 “El hombre bueno, del buen tesoro de su corazón saca lo bueno; y el hombre malo, del mal tesoro de su corazón saca lo malo” y en Mateo 15:19 “Porque del corazón salen los malos pensamientos, los homicidios, los adulterios, las fornicaciones, los hurtos, los falsos testimonios, las blasfemias”.El corazón del hombre no puede ser remendado, la promesa de Dios es que nos dará Corazon nuevo y Espíritu recto debido a que la naturaleza humana es demasiado depravada para ser remendada. No se trata de una casa que necesita de unas cuantas reparaciones, no, la casa está podrida por completo, y los cimientos han sido destruidos, en este tiempo tanto el corazón del hombre como el corazón de la familia han sido destruidos, toda la casa se encuentra en mal estado, hay podredumbre por doquier y está a punto de desplomarse. Dios no intenta repararla, no la adorna ni la embellece, ni le pone máscara como hacemos nosotros, sino que decide que la vieja casa debe ser arrasada, y que construirá una casa nueva, la Palabra dice en Ezequiel 36:26-27 "Les daré corazón nuevo, y pondré espíritu nuevo dentro de vosotros; y quitaré de vuestra carne el corazón de piedra y pondré un corazón de carne…”, ya que para poder enfrentar estos tiempos difíciles debemos tener un corazón sano delante de Dios y delante de los hombres, por lo tanto tienes que saber que Dios ama nuestro corazón; Nuestro corazón es el órgano espiritual donde Dios quiere obrar el mayor de sus milagros, es momento de que lo abras, y que Él pueda hacer esa obra transformadora en el corazón de tu vida, tu hogar y tu familia. Proverbios 4:20-27 el Señor nos da consejos sabios a través de la Palabra: Hijo mío, está atento a mis palabras;Inclina tu oído a mis razones, no se aparten de tus ojos; Guárdalas en medio de tu corazón;Porque son vida a los que las hallan, y medicina a todo su cuerpo.Sobre toda cosa guardada, guarda tu corazón; Porque de él mana la vida.Aparta de ti la perversidad de la boca,Y aleja de ti la iniquidad de los labios.Tus ojos miren lo recto,Y diríjanse tus párpados hacia lo que tienes delante.Examina la senda de tus pies, y todos tus caminos sean rectos.No te desvíes a la derecha ni a la izquierda;Aparta tu pie del mal.En la Biblia hay muchos acontecimientos registrados de sanidad en un corazón roto: La mujer encorvada, la mujer del flujo de sangre, la hija de Jairo, el paralítico de Bethesda, el ciego bartimeo, la hija de Jairo, en fin, muchas sanidades, milagros y prodigios, pero me llama mucho la sanidad del corazón roto de la mujer que fue sorprendida por los teólogos, lideres religiosos, conocedores de la ley y en un alto grado de influencia espiritual en sus pecados de Indole emocional y sexual, esto se encuentra en Juan 8:1-11 “y Jesús se fue al monte de los Olivos. Y por la mañana volvió al templo, y todo el pueblo vino a él; y sentado él, les enseñaba. Entonces los escribas y los fariseos le trajeron una mujer sorprendida en adulterio; y poniéndola en medio, le dijeron: Maestro, esta mujer ha sido sorprendida en el acto mismo de adulterio. Y en la ley nos mandó Moisés apedrear a tales mujeres. Tú, pues, ¿qué dices? Mas esto decían tentándole, para poder acusarle. Pero Jesús, inclinado hacia el suelo, escribía en tierra con el dedo. Y como insistieran en preguntarle, se enderezó y les dijo: El que de vosotros esté sin pecado sea el primero en arrojar la piedra contra ella. E inclinándose de nuevo hacia el suelo, siguió escribiendo en tierra. Pero ellos, al oír esto, acusados por su conciencia, salían uno a uno, comenzando desde los más viejos hasta los postreros; y quedó solo Jesús, y la mujer que estaba en medio. Enderezándose Jesús, y no viendo a nadie sino a la mujer, le dijo: Mujer, ¿dónde están los que te acusaban? ¿Ninguno te condenó? Ella dijo: Ninguno, Señor. Entonces Jesús le dijo: Ni yo te condeno; vete, y no peques más, la Palabra muestra la gracia y el amor de Dios hacia esta mujer, ya que Jesús no la condenó y lo que la llevó a su sanidad plena fue lo que Jesús le dijo “Mujer arrepiente y no peques más”.Muchos de nosotros no podemos amar de la manera correcta porque no hemos recibido amor de la manera correcta, en 1 Juan 4:19 la Palabra dice “Nosotros le amamos a Él porque Él nos amó primero”, por lo tanto no podemos dar algo que no hemos recibido; hoy Dios quiere mostrar su amor para con nosotros, quiere sanar nuestro corazón roto para poder amar y a través del amor de Dios en nosotros poder tomar la decisión de perdonar ya que es la base de la sanidad de un corazón roto, para volver a amar hay que perdonar y para poder perdonar hay que recibir perdón.Ministración: Debemos “Sanar la causa del Dolor”, las viejas heridas tienen buena memoria y hoy es el día de vernos como en un espejo para ver reflejado lo que hay en nuestro corazón; si observas detenidamente, veras tus heridas que han sido sanadas por el Señor, que aunque están las marcas, si las tocas ya no duelen; pero si miras cuidadosamente verás ciertas heridas que no han sido sanas, que todavía duelen, que fueron hechas por personas a las que les permitimos que entraran en nuestras vidas y trajeron consigo maldición, deshonra, destrucción, dolor y esas heridas aún están allí, porque aún no han sido perdonadas, aún no han sido sanadas; vas a observar otras heridas que nos hicimos nosotros mismos a través de los pecados que hemos cometido.Hoy me doy cuenta que aunque Cristo murió para darnos libertad, aún no la hemos recibido y vivimos bajo el yugo de la falta de perdón; por tal razón nos sentimos culpables por lo que hacemos y nos sentimos avergonzados por lo que somos. En ese espejo nos vemos horrendos, por lo tanto debemos tomar la decisión de romper la imagen del pasado, es necesario que llevemos nuestra imagen distorsionada delante del Señor, para que Él a través de Su amor y Su misericordia nos trasforme y la única manera es permitir que Dios a través del sacrificio de Su hijo Jesucristo lo haga hoy en nosotros, permitir que sane todo lo que hay dentro de nosotros: Sentimientos, emociones, la memoria donde están almacenados los eventos que han producido tanto dolor, es urgente que Dios sane nuestro corazón roto, para que podamos tomar decision...

In today's episode, we dive into the crucial roles that gut-derived microbial metabolites, particularly short-chain fatty acids and tryptophan metabolites, play in supporting the health of neurons and glial cells, ultimately promoting cognitive function. We explore how enhancing the body's natural production of these metabolites through a healthy gut microbiome and how strategic supplementation can both benefit brain health. The discussion includes detailed insights into the cellular mechanisms in the brain and practical strategies for fostering a healthy gut microbiome capable of producing high quantities of these beneficial compounds. Topics: 1. Introduction to Brain Cellular Makeup - Overview of Neurons and Glial Cells - Neurons: Structure and Function - Glial Cells: Types and Roles 2. Neuronal Communication and Synaptic Function - Neuronal Structure: Soma, Dendrites, Axon - Synaptic Communication: Presynaptic Terminal, Synaptic Cleft, Postsynaptic Membrane 3. Energy Demands - ATP Utilization and Energy Demands - Mitochondrial Function and Neuronal Vulnerability 4. Astrocytes and Microglial Cells - Astrocytes: Functions and Role in CNS Homeostasis - Microglial Cells: Immune Functions and Role in Neuroinflammation 5. Roles of Gut-Derived Microbial Metabolites in Supporting Brain Health - Overview of Gut-Derived Metabolites - Short-Chain Fatty Acids (SCFAs): Acetate, Propionate, Butyrate - Tryptophan Metabolites: Indole, Indole-3-Propionate (IPA) 6. Impact of Gut-Derived Metabolites on Neurons - Promotion of Neurogenesis by SCFAs - Neuroprotective Effects of Tryptophan Metabolites 7. Impact of Gut-Derived Metabolites on Glial Cells - Impact on Astrocytes - Impact on Microglial Cells 8. Strategies to Enhance Metabolite Production - Diversity - Probiotic Supplementation - Fiber - Amino Acids 9. Direct Supplementation Options - Sodium Butyrate: Role in Neuroprotection and Cognitive Function Thank you to our episode sponsors: 1. Check out ⁠Daily Nouri⁠ and use code ⁠CHLOE20⁠ for 20% off your order. 2. Check out ⁠⁠AX3 Astaxanthin⁠⁠ and use discount code ⁠⁠CHLOE20⁠⁠ for 20% off your first order. 3. Check out ⁠⁠⁠⁠⁠⁠Liver Medic and use code Chloe20 to save 20% on ⁠⁠⁠⁠⁠⁠⁠⁠⁠"Leaky Gut Repair"⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠Brendan's YouTube Channel⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠https://x.com/livermedic⁠⁠⁠⁠⁠⁠⁠⁠ Thanks for tuning in! Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Follow Chloe on TikTok @chloe_c_porter Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to purchase products, subscribe to our mailing list, and more! --- Support this podcast: https://podcasters.spotify.com/pod/show/chloe-porter6/support

Many know Necole as the successful former celebrity blogger of Necole Bitchie and media mogul of xoNecole- however, similar to most women, she spent years overworking, skipping meals, and forgetting to prioritize self-care while hustling her way to success in an unhealthy way. And her periods were debilitating! After learning about hormonal imbalances and their very real impacts on our reproductive health, she launched My Happy Flo. In this episode, Necole gave a mini-masterclass on hormonal health. I literally had to take notes! We discussed: Tips for a less painful periodHow My Happy Flo helps The role that nutrition plays in hormonal healthThe link between gut health and hormonal healthWhy Necole decided to launch My Happy FloResources mentioned in this episode:Spain to reportedly offer three days of menstrual leave every monthWhat is I-3-C? (Indole 3- Carbinole)What is DIM (Diindolylmethane)?How Birth Control Pills Affect Your Nutritional NeedsPost-Birth Control Syndrome Blood Tests without Insurance- Jason HealthNecole's Book recommendation: The Fifth Vital Sign: Master Your Cycles and Optimize Your Fertility by Lisa Hendrickson-JackWhere to find Necole online:Visit My Happy Flo!Follow My Happy Flo on Instagram!Follow her on Instagram (she also shares a TON of gems here!) See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Vandaag gaan we diep en hardcore met hormoon- en leefstijlspecialist Ralph Moorman. Hij begeleidt al dertig jaar mensen bij het afvallen en hun hormoonhuishouding. Er zullen enge termen klinken als insulineresistentie en laaggradige ontstekingen, maar Suzanne zorgt ervoor dat het begrijpelijk blijft. Ze hebben het over het belang van gezonde voeding, krachttraining, stressbeheersing én goed slapen. En wat is nu het beste dieet in de overgang?Shownotes:Wie is Ralph Moorman?De supplementen DIM en Indole-3-Carbinol kunnen helpen bij het op een gezonde manier afbreken van oestrogeen. Get full access to 'We zijn toch niet gek?' at suzannerethans.substack.com/subscribe

Episode #149 In this Fasting Q&A episode, hosted by Coach Lisa Chance, Dr. Jason Fung answers questions from the TFM Community: I've heard you've written an amazing book called, “The Cancer Code.”  I haven't read it yet, but wanted to hear your thoughts on broccolini being an anti-cancer food.  I understand it contains Sulforaphane, Indole-3-carbinol (I3C), Glucosinolates, Vitamin C, and fiber.  Should I concentrate on cruciferous vegetables, like broccolini, or just work on getting a balanced diet?  What are your thoughts? [02:14] I have a little confusion about the difference between taking metformin and injecting insulin. From what I've read in your books it's that insulin is going to make type 2 diabetes worse in the long run. I already know that that's not the answer to reverse type two diabetes and I'm not taking either one. Like insulin, will metformin also be detrimental to treat T2D or is there a difference between one and the other - and why, please? [05:27]  What do they mean by 'immunoreactive insulin'? [12:06] Does the liver respond negatively to the ingestion of supplements? In other words, do the supplements cause any changes in my insulin? [14:52] I started TRE (beginning Jan this year) at about 135 pounds and am now doing 24-hour fasts with OMAD and 2MAD. I have completed a 42-hour fast and will probably try another one this week. I am eating whole foods. Avocados are my miracle!!!  I do not snack between meals. My body is still releasing weight with what I am doing now and I feel I have another 5 pounds to go. How will I know when to stop shedding the weight? [18:13] Can you clarify the role of physical activity and exercise in weight loss? In The Obesity Code, you shared that a number of rigorous clinical trials demonstrate that exercise contributes minimally, if at all, to weight loss. However, zone 2 exercise is promoted for its'fat burnin' benefits. I plan to continue exercising for its health-promoting benefits but I would really like to hear your take on the extent to which it can assist with weight loss, and what exercise types you recommend for weight loss. [21:56] On non-fasting days, what is Dr. Fung's chosen style of eating? [29:46]   Please note that you need to be a member of the TFM Community to submit questions to the Q&A webinars with Dr. Fung but you can submit questions to our regular Q&A episodes here: https://bit.ly/TFMPodcastQs   Transcripts of all episodes are available at www.thefastingmethod.com on the Podcast page. Learn More About Our Community: https://www.thefastingmethod.com Join our FREE Facebook Group: https://bit.ly/TFMNetwork Watch Us On YouTube: https://bit.ly/TFMYouTube Follow Us on Instagram: @fastingmethod   This podcast is for educational purposes only and is not a substitute for professional care by a doctor or other qualified medical professional. You should always speak with your physician or other healthcare professional before doing any fasting, changing your diet, taking or adjusting  any medication or supplements, or adopting any treatment for a health problem. The use of any other products or services purchased by you as a result of this podcast does not create a healthcare provider-patient relationship between you and any of the experts affiliated with this podcast. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease.

Cruciferous vegetables, like broccoli, kale, arugula, cabbage, and radishes, are sometimes called "super foods." But why? How are they good for you? In this episode, Tina and Leah answer these questions and discuss ways crucifers can be part of a healthy diet. They touch on some of the supplements that come from crucifers, too. So, hit play, and you may hear the best broccoli joke you've ever heard. A thorough (and technical) review on cruciferous vegetables - Linus Pauling InstituteLink to buy lids  for sproutingTina's review on iodine and Cancer in NMJSupport the showOur website:https://www.thecancerpod.com Have an idea or question? Email us: thecancerpod@gmail.comJoin our growing community, we are @TheCancerPod on: Instagram Twitter Facebook LinkedIn THANK YOU for listening!

 Role of Stem Cells in the BodyThe versatile Stem Cells serve as the body's internal repair and regeneration system, orchestrating a symphony of healing processes that keep us functioning optimally. Imagine a team of construction workers rebuilding a damaged structure. Stem Cells play this exact role in our bodies. What harms our Stem Cells.Drinking too much alcohol.Smoking and general all kinds of drugs. Diabetes or high blood sugar.Lifestyle Factors.Have an active lifestyle & work out often.Regular physical activity promotes the release of growth factors that activate stem cells, contributing to tissue repair and regeneration.Sleep and Stress ManagementAdequate sleep and stress reduction techniques are essential for maintaining optimal stem cell function. High-stress levels and sleep deprivation can hinder stem cell activity.Gut-Brain ConnectionA healthy gut microbiome is closely linked to stem cell health. Consuming fermented vegetables/fruits/soya beans, probiotics and prebiotics can help maintain a balanced gut, positively impacting stem cells.Balancing Stem Cell Production.Achieving a well-rounded diet and lifestyle that includes these stem cell-friendly factors can promote a healthier stem cell population within your body.Foods to AvoidProcessed foods, excessive sugar, and trans fats can harm Stem Cells and impair their functionality. All Vegetable oils, including virgin olive oil, because they produce the most toxic aldehyde in the body from its unsaturated fatty acids, are worse for digestion and good for getting dementia…  All kinds of fish, meat, and poultry, because they make the body acid, destroy the healthy gut microbiome, and are toxic. The animals consume (most consumed fishes are farmed fish) toxic food, drugs, and antibiotics.Reducing the consumption of these items is vital for overall health. Best food for stem cells: ‍Ginger root and turmeric: typically utilized in Thai cooking to help settle indigestions. Ginger is understood to combat inflammation by reducing polyunsaturated fatty acids that can activate an inflammatory reaction. Mushrooms: High in micronutrients known as polyphenols. These nutrients are Stem Cell enhancers and can be found in plant-based diets. They help protect and cleanse liver cells from harmful contaminants that can break down hormones in the body.Seed and Nuts: Excellent snacks filled with protein and beneficial fats that keep you feeling full longer and assist in eliminating any cravings. Seeds consist of anti-inflammatory plant sterols, while nuts are filled with alpha-linolenic acid, a type of inflammatory combating omega-3 fat. Flax seeds for omega-3 fat.Cruciferous veggies: Cauliflower, Broccoli, kale, cabbage, bok choy, garden cress & Brussels sprouts are some of the best foods for stem cell growth. These veggies have lots of the sulforaphane compound, which boots enzymes in the liver that combat harmful contaminants we may digest or take in. These green leafy veggies are likewise packed with Indole-3-carbinol particles that help reduce inflammatory agents in the bloodstream.Berries: Blackberries, goji berries, pomegranate, blueberries, and raspberries all contain superoxide dismutase (SOD), a powerful antioxidant. This enzyme has incredible inflammation-reducing flavonoids and is excellent for lowering oxidative-associated stress, which is an essential consideration for optimum liver health and helps avoid joint pain. A short list Dark cacao powderGreen teaGreen beansGinger, Turmeric Greens, Kale, spinachMushroomsBlueberriesWalnuts, Flax seedsPurple potatoesMangoesMy Video: Food that Reactivates Our Stem Cells https://youtu.be/cAbpWyNhynA My Audio: https://divinesuccess.net/wp-content/uploads/2021/Podcast3/Food-that-Reactivates-Our-Stem-Cells.mp3 

This month on Episode 57 of Discover CircRes, host Cynthia St. Hilaire highlights three original research articles featured in the February 2nd and February 19th issues of Circulation Research. This Episode also includes a discussion with Dr Kathryn Howe and Dr Sneha Raju from University of Toronto, about their manuscript titled Directional Endothelial Communication by Polarized Extracellular Vesicle Release.   Article highlights: Ren, et al. ZBTB20 Regulates Cardiac Contractility Faleeva, et al. Sox9 Regulates Vascular Extracellular Matrix Aging Bai, et al. PKA Is Critical for Cardiac Growth Wang, et al. Indole-3-Propionic Acid Protects Against HFpEF

Liesanne Bouwma werkte jarenlang als uro-gynaecoloog in diverse ziekenhuizen. Uit onvrede met de vrouwenzorg richtte ze haar eigen specialistisch centrum op: Karmenta. Bij haar kun je terecht als je van de richtlijn wilt afwijken, want die vindt ze onnodig star en voorzichtig. Een grote groep vrouwen is er niet mee geholpen. Maar denk niet dat je alles voor elkaar krijgt. Ze is bovenal arts en wil haar patiënten niet schaden. We hebben het over de richtlijn, haar volgorde in behandeling, testosteron en ook waarschuwt ze voor een te hoge dosis oestrogeen. En daarover liegen tegen je arts.Shownotes:Zelfstandig behandelcentrum Karmenta in Schijndel.Het voedingssupplement Indole-3-Carbinol is goed bij pijnlijke borsten en werkt - bewezen - preventief voor borstkanker.Om uit te printen en mee te nemen naar de huisarts: de richtlijnen. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit suzannerethans.substack.com/subscribe

In this episode of “How Do You Say That?!” sponsored by britishvoiceover.co.uk, Katy Maw joins Sam and Mark to talk about finding our quiz show personas, how to voice successfully despite personal tragedies, and making sure you approach a script with conviction because "If you hold back people hear it".Our VO question this week is all about whether it's worth taking a travel kit away with you on holiday.We'd love you to join in and send us your version of one of the reads in today's show – just pop it onto an mp3 and send it to podcast@britishvoiceover.co.ukScript 1·Welcome contestant! Have you got what it takes to take on our quiz?·Hello there! Are you ready for a quizzing good time?·Let's welcome our next contestant!·It's time, to GET QUIZZY!!!·It's time to give the wheel another spin.·Round it goes, round it goes. Where it stops, nobody knows!·Let's hope you get a better category this time.·Oooh, the anticipation is killing me!Script 2There are 6 primary gases that have the most significant impact on the distinctive odour of a decaying body. These are:Cadaverine (rotting fish odour)Putrescine (faeces odour)Indole (sticky sweet odour)Hydrogen sulphide (rotten egg odour)Methanethiol (rotting cabbage odour)Dimethyl disulphide & Trisulphide (foul garlic odour)By far the most common gases that contribute to the putrid smell of a cadaver are cadaverine & putrescine.**Listen to all of our podcasts here - you can also watch on YouTube, or say "Alexa, Play How Do You Say That?!"About our guest: Katy has been voicing for 24 years now after becoming a classically trained actor in London. She works daily, predominantly on corporate & commercial scripts & has voiced literally thousands of local & National radio ads over the years and she works across all other mediums of voicing, like e-learning and IVR, narration and dubbing/ADR. She has been seen & heard on television and film sporadically over the years (Sherlock, Eastenders) and has, in more recent years, started voicing video games and audio drama as she gets back into her dramatic acting.Her clients include Amazon, Blizzard, Warhammer, ASDA, T K Maxx, Global, Bauer, ITV & the BBC, but that is just the tip of the Blue Chip iceberg. A natural RP speaker but equally at home using accents particular when she gets to use her Bristolian home town accent! Katy's Website @katy.maw on Instagram Katy's Facebook page @KatyMawMedia on TwitterResources: Howjasay Mark's demos & contact details: https://linktr.ee/britishvoiceovermarkSam's demos & contact details:

Audio only - for the full video, visit: https://youtu.be/75WaOWBJa98

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.04.25.538200v1?rss=1 Authors: Peng, Y., Zhang, Y., Fang, R., Jiang, H., Lan, G., Liu, Y., Nie, Z., Zhang, S.-D., Ma, Y., Yang, P., Wang, F., Ge, H.-H., Zhang, W.-D., Luo, C., Li, A., He, W. Abstract: Centromere protein A (CENP-A) is a centromere-specific protein that determines kinetochore positioning and the accuracy of chromosome segregation. Despite its recognized importance in maintaining mitotic fidelity, the molecular details of CENP-A regulation in mitosis are still obscure. We performed a structure-activity relationship (SAR) study of the cell cycle-arresting indole terpenoid mimic JP18 and identified two more potent analogues, (+)-6-Br-JP18 and (+)-6-Cl-JP18. Tubulin was identified as a potential protein target of these two halogenated analogues by using the drug affinity responsive target stability (DARTS) based method. X-ray crystallographic analysis determined that (+)-6-Br-JP18 and (+)-6-Cl-JP18 bind to the colchicine-binding site of beta-tubulin. We further found that treatment of cancer cells with microtubule-targeting agents (MTAs), including these two compounds, upregulated CENP-A by destabilizing Cdh1, an E3 ubiquitin ligase component. The mechanistic study revealed that Cdh1 mediates proteolysis of CENP-A in mitosis, specifying the role of Cdh1 in maintaining mitotic fidelity. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.03.21.533660v1?rss=1 Authors: Ding, Y., Yanagi, K., Yang, F., Callaway, E., Cheng, C., Hensel, M., Menon, R., Alaniz, R., Lee, K., Jayaraman, A. Abstract: Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in Western countries. There is growing evidence that dysbiosis of the intestinal microbiota and disruption of microbiota-host interactions contribute to the pathology of NAFLD. We previously demonstrated that gut microbiota derived tryptophan metabolite indole-3-acetate (I3A) was decreased in both cecum and liver of high-fat diet-fed mice and attenuated the expression of inflammatory cytokines in macrophages and TNF-a and fatty acid induced inflammatory responses in an aryl-hydrocarbon receptor (AhR) dependent manner in hepatocytes. In this study, we investigated the effect of orally administered I3A in a mouse model of diet induced NAFLD. Western diet (WD)-fed mice given sugar water (SW) with I3A showed dramatically decreased serum ALT, hepatic TG, liver steatosis, hepatocyte ballooning, lobular inflammation, and hepatic production of inflammatory cytokines, compared to WD-fed mice given only SW. Metagenomic analysis show that I3A administration did not significantly modify the intestinal microbiome, suggesting that I3As beneficial effects likely reflect the metabolites direct actions on the liver. Administration of I3A partially reversed WD induced alterations of liver metabolome and proteome, notably, decreasing expression of several enzymes in hepatic lipogenesis and {beta}-oxidation. Mechanistically, we also show that AMP-activated protein kinase (AMPK) mediates the anti-inflammatory effects of I3A in macrophages. The potency of I3A in alleviating liver steatosis and inflammation clearly demonstrates its potential as a therapeutic modality for preventing the progression of steatosis to NASH. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Grandpa Bill today continues talking about sprouting an inexpensive easy to do nutritious way to fight polluntants. Grandpa Bill Asks: Do You Have Sprouting Recipes to Share? What's Your Favorite Way to Sprout? PLEASE INTERACT LEAVE ME MESSAGES AT MY BH SALES ANCHOR RADIO MESSAGE BOARD https://anchor.fm/bhsales/message When we daydream, more parts of our brain are activated than when we're concentrating. The best way to activate the kind of daydreaming which inspires great thinking is to engage in a task which requires a relaxed attention, typically something monotonous or repetitive. Mason Jars Grow Your own sprouts+ Health Ranger Icp+ The dioxins take 500 - 1,000 years to disappear from the soils. They contaminate rivers and crops, and they are extremely dangerous at ridiculously small doses. (Less than a drop.) (edited) The good news is that you can literally grow your own natural molecules at home in a sprouting jar. This will create a molecule called Indole-3-Carbinol (I3C) which can counter dioxin exposure. compounds in cruciferous vegetables like broccoli (and kale) prod cells to get rid of certain air pollutants. Animal model studies have shown that when vegetables containing glucoraphanin are chewed or swallowed, another compound called sulforaphane appears on the scene and kicks enzymes into action to take up pollutants and clear them from the body in urine. In other words, sulforaphane seems to act like fuel for the body's own trash collection and disposal services. Most of the health benefits of broccoli sprouts come from their high level of glucoraphanin. Your body converts this compound into sulforaphane, which protects your cells against inflammation and a wide variety of diseases.Some common health benefits of broccoli sprouts include:Cancer PreventionMany studies over the years have confirmed that eating cruciferous vegetables (like broccoli, cauliflower, kale, and cabbage) raw or lightly cooked can protect against a number of cancers. Sulforaphane from these foods slows tumor growth and stops benign carcinogens from converting into active ones. In one study, researchers found that just 3 to 5 servings of cruciferous vegetables each week reduced cancer risk by up to 40%. #Health, #wealth,#DIY,#dioxins,#sulfurophane,#glucoaphanin,#wellness,#sprouts,#health,#alternative health,#holistic health, --- Send in a voice message: https://podcasters.spotify.com/pod/show/bhsales/message

Centrapeak: Promo Code: Redefine20Welcome to our latest episode of Health & Fitness Redefined, where we dive deep into the world of testosterone! Testosterone is a vital hormone that plays a key role in building muscle, boosting sex drive, and promoting overall health in both men and women.In this episode, we explore what testosterone is, how it works, and what you can do to naturally increase your levels. I share valuable insights on the benefits of maintaining healthy testosterone levels and how to avoid common pitfalls that can lower them.We cover a range of topics, including the best foods to eat for testosterone, the benefits of resistance training, and the importance of sleep and stress management. Plus, we delve into supplements that can help regulate your testosterone levels, such as Zinc, Magnesium, and D-Aspartic Acid.If you're looking to improve your overall health and vitality, and want to learn how to maximize your testosterone levels naturally, then this episode is a must-listen. So grab your headphones and join us for an informative and engaging discussion.Don't forget to like, share, and subscribe to our channel for more expert insights on health, wellness, and performance optimization.___________Attention men! Are you tired of feeling sluggish and unmotivated? Do you struggle to find the energy to hit the gym or tackle your daily tasks? If so, it's time to try Centrapeak, the all-natural male vitality product that focuses on increasing testosterone to help you feel better and more energized.Centrapeak has been around for over five years, and it's no wonder why. This vegan product is made in the USA and is certified by both the UL and the NPA, so you can trust the quality of the ingredients. Speaking of ingredients, Centrapeak's unique blend of Vitamin D3, Zinc, Vitamin B6, Boron, Phosphatidylserine, Indole-3-Carbinol, Ashwagandha, Mucuna Pruriens, Rhodiola Rosea, Pine Bark Extract, L-Tyrosine, Korean Panax Ginseng, Luteolin, and Magnesium work together to give you that extra push you've been waiting for.Now, Centrapeak isn't just for powerlifters - it's for the everyday man who wants to feel better and more confident. It's research-backed and has all the natural boosting ingredients you need to increase your energy levels, build some strength, and recharge your confidence to get started.So, if you're ready to take the next step and improve your quality of life, give Centrapeak a try. And, as an added bonus, use my affiliate link to purchase Centrapeak and receive a special discount: https://centrapeak.com/#ref=63d16332251e5 . Don't settle for feeling average - be your best with Centrapeak.--------------------------------------------------------------------------------------------Ready to get started on your HEALTH & FITNESS JOURNEY? Book your free assessment today!

Salads get a bad name because when a lot of people think of salads they think green lettuce, tomatoes, a few carrots, and salad dressings, they are even selling salads in bags now to make things easier, but if you are not careful, it is easy to make a salad inflammatory by adding things that can make it taste good but void of the nutrients needed. On this week's episode of Living Inflammation Free, we talk about building a good, tasty savory, healthy salad. To get you started we have a few recipes to help you out, and we even teach you how to make your own oil-free salad dressing; believe it or not, it is really simple. Do you have questions about your wellness routine and boundaries? We are all about community and wellness in this episode so let's jump right into it. [05:11] Your Salad base [07:45] The best ingredients to build your Salad [15:30] How to get the best store-bought Salad dressing [17:36] How to make your Salad dressing: Lemon Vinaigrette SALAD RECIPE (Serves 1 to 2) 1 handful of leafy greens: kale, Swiss chard, watercress, arugula, spinach (Do not exceed 10 cups per day) 1 handful of broccoli (The best source of sulforaphane which promotes liver detoxification, and Indole-3-carbinol, an anticarcinogenic compound) 1/4 cup Broccoli Sprouts (page 20) (Concentrated sulforaphane & I3C. Do not exceed four cups of sprouts per day) 1 handful of cauliflower 1 to 3 purple cabbage leaves, chopped (cheapest source of antioxidants per ounce in the world!) 1 red, yellow, or green pepper, sliced 1 to 2 slices of red, yellow, or green onion 1/2 leek, sliced, washed, and rinsed in a colander Mushrooms (Bella, cremini, or shiitake) 1/2 avocado, sliced 1 to 3 tbsp sunflower seeds (sprouted is better) 1 to 3 tbsp hemp seeds 1/2 cup legumes, sprouted (garbanzo beans, lentils, mung beans) or cooked (black, garbanzo, kidney beans, …) 1 large apple (yes apple for sweetness) Now from here, you can get imaginative. I like to add -Sauerkraut Once done, add spices and herbs for more flavor. Mix fresh or dried one tablespoon of oregano, garlic powder, turmeric, black pepper, Italian seasoning or Bragg Organic sprinkle, one teaspoon of cayenne pepper, and two tablespoons of nutritional yeast. Each of these spices adds flavor and has anti-inflammation and anti-cancer properties; keep in a small mason jar or resealable container and shake until well mixed. INGREDIENTS FOR LEMON DIJON DRESSING Dijon mustard - rich, creamy depth of flavor Apple cider vinegar - for a sour bite Lemon juice - fresh is best for zip and brightness Garlic - freshly minced adds pungency and flavor Salt - sea salt or Kosher to elevate and enhance flavors Maple syrup - smooths out the sharpness Cracked black pepper - for a spicy peppery flavor Fresh or dried oregano or thyme - any combination of herbs to add flavor Hot pepper flakes - a hint of heat ¼ avocado - optional for richness and creaminess INSTRUCTIONS Whisk all ingredients together in a bowl or jar. If adding avocado (for richness and creaminess), place all ingredients in the blender and process until smooth. Store in the fridge in a jar or air-tight container for up to a week. LINKS MENTIONED IN THIS EPISODE + Download the living inflammation-free food and pantry Guide https://bit.ly/Pantryguide + @inflammationfree on Instagram + Join the Facebook Community Brown Women Wellness SUBSCRIBE + REVIEW ON APPLE PODCASTS Thank you for listening. We hope this podcast has been informative & an inspiring resource to create the kind of life you want with your health in mind. To help get this podcast in front of more women like you, please consider leaving us a rating and review on Apple Podcasts here! The 10 seconds you take doing, this means the WORLD to us and the women who this show will help.

Love them or loathe them Brussels sprouts are synonymous with Christmas and so we thought an entire episode dedicated to them would be suitably festive. They also pack a pretty mean punch flavour and nutrition wise being that they are high in powerful compounds such as Indole-3-carbinols and sulforaphane that have been linked to myriad positive health benefits. They are also rich in raffinose which, although good for our gut bugs, is kind of the reason for their less…erm..'festive' gassy side effects. We wanted to test Brussels sprouts to the max so in this challenge both of us have to eat Brussels sprouts every day for 12 days. They can be cooked in any way we want but we do need to have them daily. Does this reaffirm Rose's adoration of the little green fellas or does she actually feel green herself after 12 days straight on the sprouts? And can Eve actually complete one challenge this season?  Listen to find out! This season is kindly sponsored by Ancient and Brave. Head to https://ancientandbrave.earth for more info. Some of our suggestions for tasty sprouts throughout Christmas!Raw honey glazed BrusselsIngredients1 lb. Brussels sprouts, cleaned and halved2 tbsp. extra-virgin olive oil1/2 c. good quality balsamic vinegar2 tbsp. raw local honey1 tbsp. dijon mustard2 cloves garlic, mincedHimalayan saltFreshly ground black pepperMethodIn a large skillet over medium heat, heat oil. Add Brussels sprouts, cut side down, and cook 3 to 4 minutes, until golden on the bottom. Add ¼ cup water and cover. Let Brussels sprouts steam until tender, 3 minutes. If the skillet seems dry, add more water a tablespoon at a time.Remove sprouts from skillet and set aside on a plate. Add vinegar, honey, mustard, and garlic and whisk to combine. Bring to a simmer and cook until thick and syrupy, 6 to 8 minutes. Return sprouts to pan, toss to coat, and heat through, 2 to 3 more minutes. Season with salt and pepper and serve immediately.Shredded lemon maple sprouts IngredientsZest of 1 lemon, plus 3 tbsp. lemon juice2 tbsp organic maple syrup 2 tsp. Dijon mustard1 clove garlic1/2 to 1/4 tsp. crushed red pepper flakes, depending on spice preference1 tbsp. Extra-virgin olive oil1 lb. Brussels sprouts, shreddedsalt Freshly ground black pepperToasted slivered almonds, for serving MethodIn a food processor or blender, combine lemon juice, anchovies, maple syrup, mustard, garlic, and red pepper flakes. Blend until smooth. (Alternatively, finely mince the anchovies and garlic and whisk into remaining sauce ingredients.) Set aside 2 tablespoons of the sauce for serving.Heat oil in a 12” skillet over medium heat until shimmering.Add Brussels sprouts and shake pan to settle them in an even layer. Cook undisturbed for 5 minutes. Add all but the reserved 2 tablespoons sauce to the skillet and season with salt and pepper. Cook, stirriThank you for listening and if you haven't already please follow the show as it really helps us - just click on the show page and press the plus sign. We also love hearing from you, so if you have a story you want to share or a suggestion or question you can email us at info@thewellnessbreakdown.co.uk or contact us on Instagram @the_wellnessbreakdown @rosemaryferguson_ and @evekalinikWe're also over on You Tube - youtube.com/@thewellnessbreakdownpod DISCLAIMER: All the advice and recommendations in this podcast is given generally. If you feel like you have any contraindications to anything we recommend please check with your healthcare provider first.

Autumn Soups for Runners As the weather changes there are lots of lovely seasonal foods to add to your menu. It's an ideal time to make warming soups, casseroles, and warm salads. The seasonal foods at this time of year are; butternut squash, pumpkin, potatoes, celeriac, green and red cabbage, kale, leeks, onions, brussels sprouts, chestnuts, apples, pears and blackberries. Our episode will focus on: ·      How adding SOUPS into your food plan may support you as a runner. ·      How to make an EASY SOUP– share all our practical tips. ·      Give some ideas for therapeutic soups using seasonal autumn vegetables to support health and running performance SHOW NOTES  (05:15) How a healthy bowl of soup may combine a balance of macro and micronutrients for good health and for pre and post fuelling plus an overview of how this may be beneficial to a runner. (09:27) Practical TIPS on how to make a tasty homemade soup using simple ingredients. We talk about making a POTLUCK soup using leftovers and also how recipes may be helpful. (13:29) Making a soup using everyday kitchen equipment plus the timesaving equipment of a blender and food processor – not essential but great if you have them.  (19:31) Some freezer and storage tips for soups. (22:22) https://runnershealthhub.com/shop/our-favourite-food-brands/ (Our favourite prepared for you soups ) (24:59) Cauliflower, Kale and Cannellini Bean Soup Cauliflower and Kale are very supportive of female hormone balance - because they contain glucosinolates which are converted to indole-3-carbinol, which has a potent hormone regulatory effect. The liver plays a key role in the production and clearing of hormones from the body - Indole-3-carbinol supports the liver detoxification processes through stimulating enzymes required to remove hormones (and other toxins) from the body. This recipe also includes TURMERIC. Runners may consider using turmeric as anti-inflammatory support for exercise-induced muscle damage, for example after hill drills or as a natural alternative to painkillers. Cannellini Beans are a great source of protein (1 cup contains 15g protein) and they are high in fibre. Also, they contain a range of vitamins, minerals and isoflavones – supportive of balancing female hormones. (28:40) Beetroot Apple and Coconut Soup Nutritional Properties of Beetroot – contain nitrates which help promote blood flow and they have been shown to help dilate blood vessels. Nitrate helps to enable an increase and efficient flow of oxygen through the blood vessels, which clearly is going to provide us with more energy and for our running. Beet greens are also nutrient dense providing calcium, iron and vitamin C. This would be a good soup to have 2 hours before a training run. (32:53) Mushroom and Chestnut Soup Use prepared vacuum-packed chestnuts which are available all year round, Chestnuts are a rich source of carbohydrate, vitamin C, folate and have lots of trace vitamins and minerals too, and contain some protein 2.4g/100g. Mushrooms are one of the few food sources of vitamin D and they contain betaglucans which are great immunomodulators so important to protect against infections of any kind.  (36:05) Our FREE Top 10 Soups for Runners Guide. https://runnershealthhub.com/free-nutrition-guides/ (Find out how to download your copy.) (37:35) Key Takeaways  1.    Soups may be a good addition to a runner's food plan so long as they are Nutrient dense and made of natural ingredients Have a balance of Macro and Micronutrients in line with plate balance concepts or your training strategy 2.    Making a Soup can be a time saver if prepared in advance and may be used as a meal replacement, addition to a meal or as a snack – remember to consider the energy (calorific value of a soup) within your overall energy...

Happy Canada Day! (The Candles of Shelburne): https://creepypasta.fandom.com/wiki/The_Candles_of_Shelburne  Intro/Outro music: Ghost Story by Kevin MacLeod Link: https://incompetech.filmmusic.io/song/3805-ghost-story  License: https://filmmusic.io/standard-license  Thumbs up to all our listeners, the community of creepypasta wiki, and the creator of this story: Indole. Without, we wouldn't have this discussion. So thank you all! (Indole): https://creepypasta.fandom.com/wiki/User:Indole  (creepypasta.wiki): https://creepypasta.fandom.com/wiki/Creepypasta_Wiki  (Splendorman!): https://www.youtube.com/watch?v=4MXYC_jX2Wc   Comment below or send us an email at aldenterigamortis@gmail.com    Also check out the title cards for each episode: http://crazonstudios.tumblr.com/  And if you want to show your support, consider becoming a Patron: https://www.patreon.com/aldenterigamortis

Many know Necole as the successful former celebrity blogger of Necole Bitchie and media mogul of xoNecole- however, similar to most women, she spent years overworking, skipping meals, and forgetting to prioritize self-care while hustling her way to success in an unhealthy way. And her periods were debilitating! After learning about hormonal imbalances and their very real impacts on our reproductive health, she launched My Happy Flo.  In this episode, Necole gave a mini-masterclass on hormonal health. I literally had to take notes! We discussed:  Tips for a less painful period How My Happy Flo helps  The role that nutrition plays in hormonal health The link between gut health and hormonal health Why Necole decided to launch My Happy Flo Resources mentioned in this episode: Spain to reportedly offer three days of menstrual leave every month What is I-3-C? (Indole 3- Carbinole) What is DIM (Diindolylmethane)? How Birth Control Pills Affect Your Nutritional Needs Post-Birth Control Syndrome  Blood Tests without Insurance- Jason Health   Necole's Book recommendation*: The Fifth Vital Sign:Master Your Cycles and Optimize Your Fertility by Lisa Hendrickson-Jack Where to find Necole online: Visit My Happy Flo! Follow My Happy Flo on Instagram! Follow her on Instagram (she also shares a TON of gems here!)  Be Well, Sis Partner: Athletic Greens: Redeem your offer of 1 free year of high-quality Vitamin D + 5 free travel packs by visiting athleticgreens.com/bewellsis   

Christopher Shade, PhD, is the founder and CEO of Quicksilver Scientific. He holds a Ph.D. in biochemistry but prides himself as the intuition-driven alchemist and innovator of liposomal and nano emulsion formulations. Chris is on the faculty at George Washington University and is a sought-after thought leader in the biohacking and functional medicine space. Chris is a student and practitioner of Dzogchen, a tradition of teaching in Tibetan Buddhism for over 20 years. He sees oneness as the highest expression of self with his explorations on the subject deeply rooted in the esoteric. Mindy Pellegrino, MA, MNT, is the Director of Content Strategy and Education at Quicksilver Scientific, where she has married her personal interests and passions for mind, body and spiritual explorations with initiatives she believes in. During this time, she has worn the hats of fitness instructor, functional nutritionist, reiki master, and business owner to name a few. [4:10] - Quicksilver's new adaptogenic product “Longevity Elite” [6:00] - Progesterone supplementation is for women AND men [12:30] - Polycystic ovarian syndrome [13:20] - Indole-3-Carbinol and Diindolylmethane (DIM) as metabolic regulators [14:45] - AMPK and liver activation [19:30] - “Push+Catch” liver detox protocol [21:40] - Estrogen and progesterone effects on liver and brain [26:30] - Glutathione and milk thistle can help w/ alcohol metabolism [32:00] - Hormone replacement therapy (HRT) and the Women's Health Initiative [35:00] - Adaptogens as an adjuvant to HRT [38:00] - Normal timeline of androgen decline throughout a woman's life [41:50] - Pregnenalone is the precursor to all adrenal hormones, including DHEA [50:00] - DUTCH testing [52:50] - Mitochondrial optimization and Quicksilver's adaptogenic formula “The One” [55:10] - Supporting cell membrane health through phosphatidylcholine, astaxanthin, and tocotrienols [62:30] - Quicksilver's “Ultra Vitamin” [66:50] - Buccal versus oral routes of supplementation [69:15] - CBD as an anxiolytic and adjuvant for long COVID [78:50] - Quicksilver's approach to chronic viral illness (e.g. EBV) References and Link Quicksilver Scientific®- Home, Youtube, Instagram (Save 10% on their product line using code "BELOVED") Dr. Chris Shade - Instagram Runga Retreat Book: Estrogen Matters, by Avrum Blumimg, MD, and Carol Tavris, PhD Joe distefano - Instagram Paul Chek - Youtube, Instagram Book: Adrenaline Dominance, by Michael Platt Big thanks to our sponsor! Waveblock: https://www.waveblock.com/ (Use Code “BELOVED” for 25% off) Show Notes | Donate Music by: Labrinth, Chancha Via Circuito, and Joaquín Cornejo --- Send in a voice message: https://anchor.fm/theholisticobgyn/message

Today's episode is part of an end of year special series. I am resharing some of my most actionable episodes to help you reduce pain on your period and pain flares in general, and to balance your hormones for better periods, less PMS and healthier cycles. I am sharing these episodes because this time of year is often when some of our endo management strategies can go out of the window (and understandably so!). We might have more sugar, less sleep, more alcohol and more blood sugar dysregulation, and as a result, these can all raise inflammation and give our bodies a hard time when it comes to clearing old and excess hormones. So come January or maybe sooner, we tend to have more PMS, worse periods and more pain. So these episodes are designed to provide you with some tips you can quickly implement if you're worried about your upcoming period, or you're feeling rough and need some tips to improve your symptoms. Now of course, it's natural that we want to indulge a bit over Christmas, and so these episodes are not about telling you to be a saint. Instead, they're about practices you can throw in that can just help lessen some of the impact. I am releasing a couple so you can choose strategies you think will help you most and so you have options, but you certainly don't have to try them all! And whilst I'm here, if you find that you want to learn more about how to eat for endo and for hormone balance, or you get to the end of the festive period and you really just want to improve your systems, I now have my Nutrition for Endo Masterclasses, which are available to buy all year round, unlike my courses. Lucky for you, they're still discounted because I haven't had time to change the prices, so you can still get each masterclass for £29.99 or you can buy the bundle for £50. You could also ask for them as a Christmas present! Finally, thank you for listening to this podcast this year, and for sticking with me even with my sporadic release dates as I navigate all of these new courses and offerings with recording my free content. I am wishing you a wonderful festive break (if you celebrate) and a very happy New Year. So, without further ado, let's get to today's episode. I really hope it helps you manage some of your symptoms over this festive period. Seven Foods To Alleviate PMS with Endometriosis Bloating? Anxiety? Tearfulness? Painful breasts? If you experience any of these symptoms, you likely experience PMS in the lead up to your period. Even though PMS is very common, it doesn't mean it's just something we have to live with - especially when we're dealing with endometriosis as well. In fact, PMS is caused by hormonal imbalances, often oestrogen dominance or excess oestrogen and sometimes low progesterone - and when we get these into balance, a lot of our endo symptoms ease too! So this week, I wanted to share with your seven foods that you can add in during your luteal phase (the phase after ovulation, before your period) that contain wonderful nutrients that have been shown to alleviate PMS and support healthy hormone balance… Leafy greens for magnesium, calcium and potassium. You guys must know by now how much I love magnesium! It helps to alleviate cramps, aids in oestrogen detoxification but also progesterone production and reduces bloating. Potassium additionally supports bloating, which is another bonus considering so many of you reach out to tell me this is one of your worse symptoms. Finally, in research calcium has been shown to help with PMS symptoms too! Add to smoothies, salads and whatever you're having for dinner - think leafy greens with each meal. Nuts and seeds, particularly sunflower seeds, sesame (tahini is best here as sesame seeds are often too small to chew and pass through undigested) and pumpkin seeds. Nuts and seeds and these three in particular are rich in magnesium, and zinc which supports healthy progesterone levels and good levels of vitamin E, which has been shown to help alleviate period pain and PMS. Add nut butter to your porridge, overnight oats and smoothies and drizzle tahini over your veggies. Protein for B6, including organic free range and pasture raised chicken and turkey, organic grass-fed beef, fish, lentils and chickpeas. B6 helps to keep blood sugar levels stable (in turn, keeping hormones balanced and anxiety and fatigue at bay) and has actually been shown to reduce PMS and depressive symptoms, and is truly a crucial vitamin for healthy hormonal balance! Try a chickpea curry for dinner and perhaps wild caught fish or another animal protein at lunch with lots of veggies and some healthy complex carbs and fat. Sweet potatoes, squash and beetroot (and all other root veggies) actually help to raise serotonin levels in our brain thanks to their complex carbohydrate content. Our feel-good neurotransmitter, serotonin works closely with oestrogen during the first half of our cycle, and when oestrogen lowers in our second half our mood can take a bit of a hit - especially if our progesterone levels aren't high enough. Eating root veggies with a good serving of protein and fat improve our mood, boost our energy and keep our blood sugar levels stable. Root vegetables also contain hormone loving B vitamins, calcium and magnesium - all great for balancing hormones and alleviating PMS. Try steaming and freezing root vegetables for smoothies or making up a lentil and beetroot salad. Peppers and other vitamin C rich foods like berries and broccoli can actually help to increase progesterone levels. Low progesterone levels can lead to PMS, anxiety, low moods, short cycles and pre-menstrual spotting. Try a salad of leafy greens, broccoli, peppers and lentils for a hit of vitamin C, magnesium and B6! Kidney beans, black beans, adzuki beans and other beans for B vitamins. B vitamins are some of the foundational nutrients behind healthy hormones - they ensure you're making healthy amounts, keep oestrogen in check, support progesterone if it's low and so much more that I'll have to do a whole podcast on them. In short, they can help alleviate PMS symptoms by making sure any excess or old oestrogen is cleared out and that you have a healthy level of progesterone in your luteal phase. Try an Italian bean salad with rocket, pumpkin seed pesto, adzuki beans, borlotti beans, olives, red onion, tomatoes, pepper, artichokes and olive oil! Broccoli sprouts, broccoli and other cruciferous vegetables for healthy oestrogen elimination. Broccoli and broccoli sprouts contain DIM and sulforaphane which support the liver to break down oestrogen in a healthy way and therefore lowers any chance of PMS symptoms. Throw a big handful or half a cup of broccoli sprouts in your smoothies or on salads, and try adding cauliflower rice to your chickpea curry. Even just adding one or two of these foods in on a daily basis could make a difference! Try making a meal plan or some meal ideas with any of the above suggestions and track how your PMS symptoms over a few cycles to see if things change. Let's get social! Come say hello on Instagram or sign up to my newsletter. Sign up to the wait list for my course, Live and Thrive with Endo here. My new Nutrition for Endo Masterclasses are out now and are on special offer for Black Friday. Get one masterclass for £29.99 (full price £40) or both for £50. Find out more here. My cookbook This EndoLife, It Starts with Breakfast is out now! Get 28 anti-inflammatory, hormone friendly recipes for living and thriving with endometriosis. Order your copy here. If you feel like you need more support with managing endometriosis, you can join Your EndoLife Coaching Programme. A 1-to-1 three month health and life coaching programme to help you thrive with endometriosis. To find out more about the programme and to discuss whether it could be right for you, email me at hello@thisendolife.com or visit my website. This episode is sponsored by The Pod Farm. Learn all about how to start your own podcast with the complete course from The Pod Farm. Aimed at beginners, this course takes a simple and straightforward approach to planning, equipment buying, setting up, recording, editing and hosting your own podcast. With hours of audio and video materials, and downloadable guides and useful links, this multimedia approach aims to have something for every kind of learner. From now until April 15, newsletter subscribers get 20% off the course price. Visit www.thepodfarm.com to enroll or find out more This episode is sponsored by BeYou. Soothe period cramps the natural way with these 100% natural and discreet menthol and eucalyptus oil stick on patches and CBD range. Click here to find out more and to shop: https://beyouonline.co.uk This episode is sponsored by Semaine. Try their supplement for period pain and daily supplement for hormonal balance and PMS prevention with code ENDOLIFE to get 20% off your first order. Show Notes Hormone balance with Nicole Jardim My blood sugar episode Lisa Hendrickson-Jack Fertility Awareness Method My FLO app Magnesium: Magnesium for oestrogen clearance The Association Between Serum Magnesium and Premenstrual Syndrome: a Systematic Review and Meta-Analysis of Observational Studies Magnesium--a new therapeutic alternative in primary dysmenorrhea Potassium: Potassium foods for bloating Calcium: A systematic review of the role of vitamin D and calcium in premenstrual syndrome Zinc: Zinc induced changes in the progesterone binding properties of the human endometrium Vitamin E: Evaluating the effects of vitamin D and vitamin E supplement on premenstrual syndrome: A randomized, double-blind, controlled trial B6: The Interactions between Vitamin B6 and Hormones Nutritional factors in the etiology of the premenstrual tension syndromes Dr Jolene Brighten B6 Vitamin C: Serum Antioxidants Are Associated with Serum Reproductive Hormones and Ovulation among Healthy Women Low progesterone B vitamins: Dr Joelene Brighten Broccoli sprouts:  Magdalena Wszelaki broccoli sprouts Changes in levels of urinary estrogen metabolites after oral indole-3-carbinol treatment in humans Indole-3-Carbinol (I3C) and its Major Derivatives: Their Pharmacokinetics and Important Roles in Hepatic Protection

Today's episode is part of an end of year special series. I am resharing some of my most actionable episodes to help you reduce pain on your period and pain flares in general, and to balance your hormones for better periods, less PMS and healthier cycles. I am sharing these episodes because this time of year is often when some of our endo management strategies can go out of the window (and understandably so!). We might have more sugar, less sleep, more alcohol and more blood sugar dysregulation, and as a result, these can all raise inflammation and give our bodies a hard time when it comes to clearing old and excess hormones. So come January or maybe sooner, we tend to have more PMS, worse periods and more pain. So these episodes are designed to provide you with some tips you can quickly implement if you're worried about your upcoming period, or you're feeling rough and need some tips to improve your symptoms. Now of course, it's natural that we want to indulge a bit over Christmas, and so these episodes are not about telling you to be a saint. Instead, they're about practices you can throw in that can just help lessen some of the impact. I am releasing a couple so you can choose strategies you think will help you most and so you have options, but you certainly don't have to try them all! And whilst I'm here, if you find that you want to learn more about how to eat for endo and for hormone balance, or you get to the end of the festive period and you really just want to improve your systems, I now have my Nutrition for Endo Masterclasses, which are available to buy all year round, unlike my courses. Lucky for you, they're still discounted because I haven't had time to change the prices, so you can still get each masterclass for £29.99 or you can buy the bundle for £50. You could also ask for them as a Christmas present! Finally, thank you for listening to this podcast this year, and for sticking with me even with my sporadic release dates as I navigate all of these new courses and offerings with recording my free content. I am wishing you a wonderful festive break (if you celebrate) and a very happy New Year. So, without further ado, let's get to today's episode. I really hope it helps you manage some of your symptoms over this festive period. Seven Foods to Alleviate Oestrogen Dominance with Endometriosis If you've listened to my podcast recently, you've likely heard a lot about oestrogen dominance or excess oestrogen and the problems these two imbalances can bring. Oestrogen in itself isn't a ‘bad' hormone - it's a wonderful hormone that plays a crucial role in our menstrual cycle and our overall health. But too much or too high in relation to progesterone is where the problems arise, and these problems can make our experience of endo worse. So what is oestrogen dominance? Oestrogen dominance occurs when the ratio of oestrogen to progesterone is too high, this can happen when progesterone is low, oestrogen is high or both! Excess oestrogen is when there is too much oestrogen circulating the body, and this would be likely cause oestrogen dominance, providing of course that progesterone isn't also too high (which in my experience with clients at least, is generally less common). Why does oestrogen dominance occur? We deep dive into this topic in other interviews and episodes (so check the links below), but to give you an overview, here are some of the common causes: Stress Imbalanced blood sugar Gut health issues Deficiencies, such as zinc Heavy alcohol consumption Overburdened liver Xenoestrogens Whilst taking a holistic approach looking at all of these areas is advisable, eating certain foods can help your body to remove any old or excess oestrogen and adding these foods in can be a great way to get started with healing any imbalances. Here are seven of my favourite foods for alleviating oestrogen dominance with endometriosis: Dandelion root tea or coffee to help support the liver with clearing out old and excess oestrogen. Be careful that you're not buying a caffeinated dandelion and coffee blend - we're looking for dandelion alone. You can drink it as a herbal tea or buy it roasted, then grind and have as coffee! It makes a lovely black coffee or latte. Broccoli sprouts provide a big, concentrated dose of SGS (sulforaphane glucosinolate) , a plant compound that also helps the liver to detoxify oestrogen and break it down in a healthy way Cruciferous vegetables such as kale, broccoli, cabbage and Brussel sprouts aid oestrogen detoxification. The active compound in cruciferous veggies is a nutrient called I3C (indole-3-cabinol), which further breaks down into SGS (sulforaphane glucosinolate) and DIM (diindolymethane) and both play a big role in supporting the liver with oestrogen detoxification. In fact, these nutrients are so powerful that you may recognise them - they're often found in oestrogen clearance supplements! Probiotic foods such as kefir, sauerkraut, kimchi and yoghurt help create a healthy gut microbiome and ensure that the bacteria which helps to eliminate oestrogen, the estrobolome, is well supported and that beta-glucuronidase, the enzyme that reactivates oestrogen (causing it to be reabsorbed into the blood stream), is prevented from getting too high. A caveat here is that if you have SIBO you may find probiotic foods aggravating. I would start slowly with one tablespoon and increase to tolerance over time. B6 foods such turkey, fish, seeds, nuts like pistachios, lentils, eggs, and a moderate amount of organic pasture-raised red meat helps to detoxify old and excess oestrogen and raise progesterone levels. Lignans from nuts and seeds, particularly pumpkin, sunflower, sesame and potentially flax (if you respond well to it) help bind and remove oestrogen. Flax can have weak oestrogenic effects, and is often recommended to help lower oestrogen dominance symptoms . However, I recommend being mindful here as I am not the only practitioner to have witnessed endo symptoms and oestrogen dominance symptoms worsening from flax, so I would just see how you personally respond. Having said that, lots of doctors, nutritionists and health coaches see an improvement, but just have an awareness when you try and if you try flax. Hopefully it works well for you!   Let's get social! Come say hello on Instagram or sign up to my newsletter. Sign up to the wait list for my course, Live and Thrive with Endo here. My new Nutrition for Endo Masterclasses are out now and are on special offer for Black Friday. Get one masterclass for £29.99 (full price £40) or both for £50. Find out more here. My cookbook This EndoLife, It Starts with Breakfast is out now! Get 28 anti-inflammatory, hormone friendly recipes for living and thriving with endometriosis. Order your copy here. If you feel like you need more support with managing endometriosis, you can join Your EndoLife Coaching Programme. A 1-to-1 three month health and life coaching programme to help you thrive with endometriosis. To find out more about the programme and to discuss whether it could be right for you, email me at hello@thisendolife.com or visit my website. This episode is sponsored by The Pod Farm. Learn all about how to start your own podcast with the complete course from The Pod Farm. Aimed at beginners, this course takes a simple and straightforward approach to planning, equipment buying, setting up, recording, editing and hosting your own podcast. With hours of audio and video materials, and downloadable guides and useful links, this multimedia approach aims to have something for every kind of learner. From now until April 15, newsletter subscribers get 20% off the course price. Visit www.thepodfarm.com to enroll or find out more This episode is sponsored by BeYou. Soothe period cramps the natural way with these 100% natural and discreet menthol and eucalyptus oil stick on patches and CBD range. Click here to find out more and to shop: https://beyouonline.co.uk This episode is sponsored by Semaine. Try their supplement for period pain and daily supplement for hormonal balance and PMS prevention with code ENDOLIFE to get 20% off your first order. Show Notes SIBO episodes Ep 99 with Dr Allison Siebecker Ep 97 My SIBO treatment plan Oestrogen dominance episodes Ep 104 Blood Sugar episodes Ep 88 Ep 81 Ep 66 Ep 55 Broccoli sprouts and cruciferous veg  Magdalena Wszelaki broccoli sprouts Changes in levels of urinary estrogen metabolites after oral indole-3-carbinol treatment in humans Indole-3-Carbinol (I3C) and its Major Derivatives: Their Pharmacokinetics and Important Roles in Hepatic Protection Estrobolome Alisa Vitti Histamine The 4-Phase Histamine Reset Plan B6 The Interactions between Vitamin B6 and Hormones Nutritional factors in the etiology of the premenstrual tension syndromes Dr Jolene Brighten B6 Lignans Dr Joelene Brighten on seed cycling and flax Lara Briden explains phytoestrogens

Track 1: Introductions Explaining different topics of discussion bloodtests Omega 3's Opioid Crisis - There is a REAL problem going on Start of article from Life Extension Foundation "Why Blood Tests Are Not Saving More Lives" The problem with bloodtests, especially with the focus on cholesterol Article focuses on heart, atherosclerosis, apolipoprotein B Jacobus explains "LDL" triglycerides and the risk factors Test for particle size of LDL   Start Track 2: 20:35 Track 2: Text Message about polyphenols and bioflavonoids  elasticity of the blood vessels Water soluble/fat soluble - viscosity of bloodflow Importance of Omega 3 Jacobus explains EPA & DHA Blood thinners Prescription - no herb starting with "G" Continue the article from Track 1 Tri-Med Services - does particle size + Apo B   Start Track 3: 42:44 Track 3: Apolipoprotein B - found on the outside of LDL surface can damage arterial walls and endothelium tissue Effect of Apo B when: elevated + "healthy" cholesterol (60% increase) elevated + "high" cholesterol (100% increase) Walnuts good for cardio health Sugar - added sugar increases apo - B Exercise - Apo B will go down Sleep - very important to lower apo - B Thyroid Hormones - low thyroid = increased cholesterol instead of statin drugs - better option is work to improve thyroid issue Effects of Fish Oil - 1 tbsp daily = 3-% reduction in production of apo - B and triglycerides analogy of fireplace: logs vs paper Acute risk of excess apo - B - ratio of apo - B vs apo - A when close = Indole 3 - cartinol will lower Apo B +/-56%   Start Track 4: 1:03:26 Track 4: Continue with Blood Testing Problems Most tests don't reveal: hormones homocysteine Apolipoprotein B Indole - 3 - Carbinol - reduces apo B by as much as 56% & also reduces excess estrogen Recap of LEF article Talk about prescription drug REPATHA Explaining TSH Range in bloodtests Explaining Vitamin D3 Range in bloodtests Explaining Hemoglobin A, C Range in bloodtests Explaining Homocysteine Range in bloodtests Explaining Testosterone - Estradiol - DHEA 5 Range in bloodtests Article about "Omega 3 Intake and Lower Risk of Mortality"  during 16 years of follow - up 240,000 + men and 181,000 women Explaining EPA and DHA Benefits Text Message: 1 slice of Bacon/Day is it bad or okay? Text Message: What about Pickle Juice is that good for arteries?   Start Track 5: 1:22:55 Track 5: Remembering Apollo 2 landing on the mood Neil Armstrong interview what happened to him & how he viewed the historic impact Buzz Aldrin - his life after Apollo 2 Call about Dutch returning DDay Flag to the US Call to repeat things that shouldn't be taken for high cholesterol   Start Track 6: 1:47:26 Track 6: Opioid Crisis Update Article released by Washington Post DEA first-time ever, that tracks every pill has been made public (the data base) Largest civil action has lead to over 100,000 death (2006-2012) Judge Dan Polster removed protective database (ARCOS)  Biggest takeaways from the article: First time ever released roadmaps to opioid epidemic companies flooded market with opioids 76 Billion oxycodone etc on the market 6 companies: 75% of all opioids distributed By contrast, doses of morphine 500 million morphine 1 year: 12,600,000,000 : 330 million people = 38 pills/person: 12 months : 1 Billion 50 million by month : 52 weeks : 242 million/ week : 365 days : 34 million/day states that received the highest concentration of pillsRural areas received a lot of pills per year numbers from MT: 245,472,116: 7 years35,067,00/year : 1 million persons = 35 per person/year Mckesson Corporation = #1 Comparing County-level opioid death in USA NY Times Article This whole system was set in place said these pills were not addictive - WRONG! Natural Alternatives for pain: Turmeric Boswellia CBD

Come si scrive la scaletta di un romanzo?

Jeremías 33:6.Para poder enfrentar estos tiempos difíciles debemos tener un corazón sano delante de Dios, por lo tanto tienes que saber que Dios ama nuestro corazón, nuestro corazón es el órgano espiritual donde Dios quiere obrar el mayor de sus milagros, es momento de que lo abras, y que Él pueda hacer esa transformación en en corazón de tu vida, tu hogar y tu familia. En el libro de Proverbios 4:20-27 el Señor nos da consejos sabios a través de la Palabra, pero el más importante de todos está en el verso 23 en el cual nos advierte que guardemos el corazón porque de el mana la vida.Dios no intenta repararlo ni mucho menos adornarlo ni embellecerlo, ni colocarle mascara como lo hacemos nosotros, sino que toma la decisión de hacerlo de nuevo y hoy es el día, está escrito en el libro de Ezequiel 36:26-27 "Les daré corazón nuevo, y pondré espíritu nuevo dentro de vosotros; y quitaré de vuestra carne el corazón de piedra y pondré un corazón de carne…”.En el corazón existen todas las áreas de nuestra vida: área física, emocional, espiritual, económica, de relaciones, y en el se almacenan todos los eventos desde el momento que somos engendrados; escuche esto: “Si éstas áreas estuvieron afectadas por eventos donde la maldad, la iniquidad, el pecado, la violencia y la deshonra estuvieron presentes, estarán en regiones oscuras o de tinieblas, la Biblia lo llama cárceles espirituales”, cuando esto ocurre el ser humano comienza a manifestar todo lo que opera en estos lugares y al final producirá enfermedades, desgracias, temores, angustias, quebrantos y se manifestará mediante la ira, la amargura, ruina, escasez, destrucción, separación, violencia, etc.En la Biblia hay muchos acontecimientos registrados de sanidad y liberación, pero me llama mucho la atención la sanidad y la liberación de la mujer que fue sorprendida por los teólogos, lideres religiosos, conocedores de la ley y en un alto grado de influencia espiritual en sus pecados de Indole emocional y sexual, esto se encuentra en Juan 8:1-11, la Palabra muestra la gracia y el amor de Dios hacia esta mujer, ya que Jesús no la condenó y lo que la llevó a su sanidad plena fue lo que Jesús le dijo “Mujer arrepiente y no peques más”.y muchos de nosotros no podemos amar de la manera correcta porque no hemos recibido amor de la manera correcta, en 1º Juan 4:19 la Palabra dice “Nosotros le amamos a Él porque Él nos amó primero”, por lo tanto no podemos dar algo que no hemos recibido; hoy Dios quiere mostrar su amor para con nosotros, quiere sanar nuestro corazón roto para poder amar y a través del amor de Dios en nosotros y poder tomar la decisión de perdonar ya que es la base de la sanidad de un corazón roto: Volver a amar y para volver a amar hay que perdonar y para poder perdonar hay que recibir perdón, entonces acuérdate de las veces que has recibido perdón de parte de Dios, asi como está escrito en Efesios 4:32 y ocurra en tu vida lo que está escrito en Isaías 61:10.Por lo tanto la única manera que esto pueda ocurrir en nosotros es “Sanar la causa del Dolor”, las viejas heridas tienen una memoria muy buena y en el momento de desarrollar esta charla delante de Dios, decidí hacer mi propia fotografía con base en lo que había en mi corazón; vi mis heridas que habían sido sanadas por el Señor, que aunque estaban las marcas al tocarlas ya no dolían, pero también vi ciertas heridas que no habían sido sanas, que todavía duelen, que fueron hechas por personas que permitimos que entraran a nuestras vidas, que trajeron consigo maldición, deshonra, destrucción y estaban allí porque aún no había perdonado; vi otras heridas que yo mismo me causé por los pecados que había cometido.Así como yo hay muchos hoy aquí en este lugar y me he dado cuenta que aunque Cristo murió para darnos libertad, aún no la hemos recibido y vivimos bajo el yugo de la falta de perdón; por tal razón nos sentimos culpable por lo que hacemos y avergonzados por lo que somos. Esto me llevó a dibujar mi propia fotografía y al terminarla la vi horrenda y tomé la decisión de romperla para borrarla definitivamente de mi vida pero antes de romperla la llevé delante del Señor para que Él a través de Su amor y su misericordia la transformara y me di cuenta que la única manera de hacerlo era permitir que Dios a través del sacrificio de Su hijo Jesucristo lo hiciera en mi, permitir que sanara todo lo que había dentro de mi; mis sentimientos, mis emociones, mi memoria donde están almacenados los eventos que produjeron tanto dolor, yo necesitaba urgentemente que Dios sanara mi corazón roto para que pudiera tomar decisiones correctas en mi vida y esa es la tarea que ha propuesto el Señor en este tiempo a su iglesia y ya muchos lo han hecho, quiero que venga aquí Diana para que en pocos minutos nos diga que ocurrió en ella.No nos escondamos más, así como lo hizo Adán y Eva y Dios tuvo que buscarlos y encontrarlos y los cubrió con vestidos de sacrificio, Génesis 3:21; mas bien dibujemos esa fotografía de todo lo que hay dentro de nuestro corazón y presentémonos delante del Señor para recibir el perdón, la sanidad, la restauración y la restitución que Él quiere traer hoy a Su Iglesia y no seguir andando por ahí con el corazón roto tomando las peores decisiones en nuestra vida.Escucha bien, yo estoy aquí para predicarles a personas que como tu y como yo necesitamos del Señor para ser sanados, para ser libres, para que Dios obre milagros y prodigios, de repentes que necesitamos que ocurran día a día en nuestra vida, familia y descendencia.Presenta tu fotografía delante del Señor cargado de pecado, iniquidad, dolor, maldición, heridas profundas, dice la Palabra en Isaías 53:3-6… Terminar con Isaías 61:10.

What is indole? What do we use it for? Last week I finished going over biochemicals for gram positive cocci. In this week I start with biochemicals for gram negative rods: indole.

Though many men worry about producing too little testosterone, many deal with elevated estrogen. In either case, the physical and mental health effects can be the same. Natural compounds like chrysin may be part of a solution, as chrysin may act as an aromatase inhibitor, reducing the conversion of testosterone to estrogen. Research shows it offers numerous other health benefits as well. What is chrysin? Chrysin is a naturally occurring polyphenol. You can extract it from: honeypropolisbitter melonwild Himalayan pearpassionflowersilver lindensome types of geranium To date, research has focused on chrysin ingestion alone. Whether it would provide any topical benefit remains to be seen. Chrysin Health Benefits Though most people learn of chrysin as an aromatase inhibitor, it affects many other aspects of health as well. Aromatase inhibition Excess estrogen in men or women contributes to physique, performance, and health problems. Like low testosterone levels, in men, excess estrogen contributes to gynecomastia (a.k.a. moobs) and other female physical characteristics. It may also increase body fat storage in the arms and hips and compromise muscle growth. Excess estrogen contributes to breast cancer, endometriosis, and difficulty improving body composition, strength, and physical performance in women. Chrysin may reduce the conversion of testosterone to estrogen. Indole-3-carbinol (I3C) and diindolylmethane (DIM) are two other popular natural products that may reduce aromatization. While they seem to be effective in some people, they don't seem to do much for me. That prompted me to investigate chrysin. Periodically, I develop mild gynecomastia on the left side of my chest. It seems to coincide with increased sun exposure, which increases vitamin D and may drive up testosterone production, which may increase testosterone aromatization to estrogen. In some men, as total testosterone levels rise, some of that extra testosterone gets converted to estrogen and can lead to undesirable effects. For me, my left nipple gets sore and firm. In the winter, it seems to go away. Animal studies and in vitro research shows chrysin does act as an aromatase inhibitor. However, there's very little in vivo research at this point. That said, it is very safe, so I ordered some to experiment on my own. Unfortunately, some supplement companies include it in “testosterone-boosting supplements.” That's pretty misleading. Chrysin does not increase testosterone but may keep estrogen levels in check or even lower them. In some men, lower estrogen leads to the same physical and mental health benefits as raising testosterone. Read also: Irritable Male Syndrome, Andropause, and Reclaiming Your Manhood. Healthy inflammation levels Like other natural compounds, such as curcumin, quercetin, and omega-3 fatty acids, chrysin supports healthy inflammation levels.  Chrysin alleviates inflammation through inhibition of COX-2, prostaglandin-E2, histamine, NF-γB pathway, tumor necrosis factor- (TNF-) alpha, iNOS, and cytokines (interleukin-1β, interleukin-2, interleukin-6, and interleukin-12) and activation of peroxisome proliferator-activated factor γ (PPARγ).Joohee Jung, Emerging Utilization of Chrysin Using Nanoscale Modification Inflammation contributes to heart disease, cancer, allergies, cognitive dysfunction, and many other conditions. Of course, a big part of staying healthy is eating well, following a good exercise program, and getting sufficient sleep. Chrysin may support better inflammation levels, but you still need to control your diet and lifestyle. Cardiovascular health Chrysin may support heart health by slowing the progression of atherosclerosis. Inflammation contributes to plaque formation, and since chrysin supports healthier inflammation levels, it may slow plaque formation. In addition, like nattokinase, chrysin may reduce cholesterol oxidation.

Éxodo 17:14-16.Cuando decides “ser cristiano” lo primero que comienzas a aprender es el “idioma espiritual”, aprendemos a hablar como un “ser espiritual” y por lo tanto muchas cosas que se mueven a nuestro alrededor son de Indole espiritual y por lo tanto debemos tratarlo en lo espiritual, la Palabra dice: “porque las armas de nuestra milicia no son carnales, sino poderosas en Dios para la destrucción de fortalezas”, 2 Corintios 10:4. Cualquier coa que esté ocurriendo en tu vida, en tu hogar y en tu descendencia debes tratarlo en el ámbito espiritual, por lo tanto tenemos que buscar la raíz espiritual de todo lo que estás viendo en estos tiempos en el área física, emocional, económico, sexual y espiritual en tu vida, tu hogar y tu descendencia.Dios pretende rectificar todo el desorden que hemos introducido en nuestra vida, hogar y descendencia, Él siempre anhela enderezar todo lo que está torcido, Él tiene un plan de redención, restauración y restitución, el cual es el deseo original de Dios para la humanidad a través del sacrificio de Cristo, el cual compró nuestra completa redención a través de Su sangre.Vamos a comenzar este tiempo de guerra espiritual hablando de un espíritu destructor llamado Amalec, quiero que pongas atención y de esta manera podamos tomar acciones firmes.Echemos un vistazo histórico de quien es Amalec, nieto de Esaú hermano de Jacob "Y Timna fue concubina de Elifaz, hijo de Esaú, la cual le dio a luz a Amalec:  estos son los hijos de Ada, mujer de Esaú.”, Génesis 36:12, y el odio que tenia Esaú hacia su hermano Jacob fue trasmitido a su descendencia por lo que decidió tomar venganza, Génesis 27:41; que a pesar que Esaú y Jacob se reconciliaron, Génesis 33:1-4, los descendientes de Esaú no quitaron de su corazón el odio, el resentimiento y el espíritu de venganza. Esta es la razón por la cual el Señor manda a romper toda causa o raíz espiritual de lo que hoy por hoy está ocurriendo en tu vida, tu hogar y tu descendencia.Aquí vemos entonces la razón por la cual Amalec atacó a Israel por la  retaguardia cuando huían de Egipto, en la  retaguardia  iban  mujeres, ancianos y niños, y fue allí donde hizo más daño, por eso el Señor mandó a borrarlos de la memoria: Deuteronomio 25:17-19, Éxodo 17:8-16. Ahora echemos un vistazo de lo que ocurrió: Mientras Josué lideraba la batalla defensiva, Moisés en la cumbre del monte levantaba sus manos con la vara de Dios. La vara significa la autoridad del Señor sobre su pueblo. Entonces sucedía algo sobrenatural: Todo el tiempo que Moisés mantenía sus manos alzadas, Israel prevalecía. Pero cuando las bajaba, prevalecía el Enemigo. Como las manos de Moisés se cansaban, fue traída una piedra y Moisés se sentó sobre ella, esa roca es Jesucristo. Luego Aarón y Hur sostuvieron las manos de Moisés, esta actitud del sacerdote y el amigo junto con la autoridad de Dios a través de la vara en la mano del profeta garantizan la victoria, necesitamos familias de sacerdotes y gente santa que tenga el valor de sostener la vara de Dios para derribar todos los enemigos que se levantan contra nuestra vida, hogar, descendencia y ministerio. Ahora miremos las características del Espíritu de Amalec:  En  hebreo. {Amâlêq, "belicoso" o "pueblo que lame”, “pueblo que ama la pelea y la contienda”). Es un espíritu sutil, que se levanta contra los propósitos que Dios tiene para tu vida, tu hogar y tu descendencia. Ataca a los débiles de la fe. Espíritu de odio y resentimiento. Espíritu vengativo. Ataca el área económica de la familia, se roba todo el Fruto de tu trabajo. Un espíritu manipulador que trabaja por la retaguardia, es el espíritu de traición. Un espíritu que te quita pasión por la presencia del Señor. Amalec trae al interior de tu vida, hogar y descendencia contiendas, peleas, gritería, maledicencia, división, adulterio, iras y como consecuencia destrucción familiar. No tiene temor de Dios. Amalec te impide el avance hacia la conquista de tus sueños, metas y propósitos de Dios. Si no derrotas a Amalec, Amalec te derrota a ti: por lo tanto hoy tienes que tomar la decisión de pararte firme y sacarlo de tu vida, tu hogar y tu descendencia, la Biblia relata el caso del rey Saul, fue elegido el primer rey de Israel. Dios ordenó a Saul a través de Samuel que tenía que exterminar al rey Agag, descendiente de Amalec, 1ª Samuel 15:1-3. Saul obedece a medias, en otras palabras desobedece la orden de Dios, 1 Samuel 15:7-11. Vinieron consecuencias para el rey Saul, (verso 16-23, 26-27). Samuel mata a Agag (verso 32-33).  Saul muere en manos de un Amalecita, 2ª Samuel 1:6-10. Hoy nos vamos a levantar con una palabra profética para exterminar a Amalec, arrancarlo definitivamente de nuestra vida, hogar y descendencia: Números 24:20. Éxodo 17:14-16. 1 Samuel 15:33.

Our guest today, Dr. Erika Ebbel Angle, is the CEO and co-founder of Ixcela - the Internal Fitness Company ( https://ixcela.com ). Ixcela is the ultimate health assessment tool to deliver nutrition, supplement, mindfulness, and fitness recommendations. By assessing 11 metabolites, you will receive a baseline health score, along with a personalized health plan. Dr. Erika shares the importance of optimizing gut health when striving for overall health, why testing is so important, what these 11 metabolites found in the blood tell us about gut health and why we should all seek microbial balance in our lives. *SHOW NOTES:* 1:21 Welcome to the show! 4:11 Dr. Erika Angle’s Bio 5:26 Welcome Erika 6:15 Erika’s health journey 8:18 The gut connection 9:18 The gut-brain axis 10:20 Renee’s experience with gut distress/anxiety 11:07 The many manifestations of anxiety 13:35 Using the test as a baseline assessment 14:42 Blood tests vs Stool tests 17:10 Measuring Tryptophan 18:06 Comparing Ixcela to urine tests 20:16 How the Ixcela test works 21:35 “Test, don’t guess” 23:24 Tryptophan, an essential amino acid 26:04 Serotonin & Leaky gut 28:30 Healing the gut 30:18 You need to know the why 31:05 The 11 metabolites on the test 33:23 Explaining the (gut) immune system 37:22 The Indole group of metabolites 43:16 Purine metabolites 45:51 The importance of testing 47:51 What does “higher risk” really mean? 50:12 “Things are constantly changing” 52:08 How often to retest 53:17 Renee’s Ixcela results 55:13 Matching test results 56:22 Interpreting & correlating the results 57:48 The importance of recovery 59:35 “Knowing is so important” 1:03:06 Seeking a microbial balance 1:09:42 Final piece of advice 1:11:52 Thanks for tuning in! *RESOURCES:* Ixcela Website ( https://ixcela.com/ ) Order your test kit here ( go.ixcela.com/enroll ) - use Pro code: RENEEBELZ for a professional discount and for an extra 10% off through January 31st use code: TRANSFORM10 Ixcela Sample Report ( https://ixcela.com/learn/example-ixcela-result-report.html ) IG: Ixcela Wellness ( https://www.instagram.com/ixcelawellness/ ) Erika's Ted Talk - Your Gut Microbiome ( https://www.youtube.com/watch?v=B9RruLkAUm8 ) Book: Eat Dirt ( https://www.amazon.com/gp/product/0062433679/ref=as_li_tl?camp=1789&creative=9325&creativeASIN=0062433679&ie=UTF8&linkCode=as2&linkId=1f647314cc85d43e07c071f1ffc6912d&tag=laurensamba04-20 ) Support this podcast at — https://redcircle.com/biohacker-babes-podcast/donations

Candace and Kyle get another chance to talk with our favorite mentor, expert and guru on hormones and hormone testing, Dr. David Zava, Ph.D., CEO and founder of ZRT Laboratory, one of the foremost hormone testing labs in the US and globally.   A biochemist by trade and a teacher at heart, Dr. Zava started out as a breast cancer researcher involved in international clinical trials looking into the development of breast cancers genetics and epigenetics of breast cancers. This is yet another challenging listen in which Dr. Zava shares his breast cancer research, as well as cutting-edge science and information women can use to prevent the hormone imbalances that put us at risk for breast cancer and what we can do to prevent a breast cancer or its recurrence. Here are some of the issues and answers we cover in this episode: Hidden hormone imbalances and risks for breast cancer What do these things have to do with breast cancer? – heavy metals/ environmental  toxins– poor diet/insulin resistance – being continually stressed out/ too much Cortisol– not sleeping well/lack of Melatonin How Environmental Chemical Carcinogens like heavy metals and xenoestrogens increase our risks for breast cancer How testing our hormones can alert us to  hormonal risks for breast cancer.  Why  estrogen is called “the Angel of Life” and  “the Angel of Death”  How the buildup of estrogen increases risk of breast cancer (BC) and how supplementing with progesterone can reduce our risk significantly When good estrogens go bad – if they go down the wrong pathways to damage DNA and lead to a BC Genetics vs. Epigenetics – which is more of a risk for BC? The importance of cruciferous vegetables, DIM, Indole 3 carbuncle assist the proper metabolism of estrogens Obesity and the insulin connection to breast cancer  Women, wine and breast cancer here and in Europe Dr. Z’s suggested breast protective supplements and lifestyle changes …and so much more… We are privileged to have Dr. Zava share his formidable knowledge about breast cancer to help women move from awareness to action and prevent a breast cancer that may be waiting to happen.  “Breast cancer risks start to show up with prolonged stress, the high cortisol levels, the lack of sleep, the low melatonin, the poor appetite, the lack of exercise, etc., but if we improve our lifestyle, keep our hormones balanced… eat the right amount of the right foods (eat the rainbow), get enough sleep in a dark room, stop smoking, eat and drink in moderation, reduce our stress levels…if we do each one of those things on a regular basis…. this is going to decrease your breast cancer risk by half.” – Dr. David Zava Listen on Apple Podcasts Listen on Spotify Show Notes to Episode Seventeen

If you’ve listened to my podcast recently, you’ve likely heard a lot about oestrogen dominance or excess oestrogen and the problems these two imbalances can bring. Oestrogen in itself isn’t a ‘bad’ hormone - it’s a wonderful hormone that plays a crucial role in our menstrual cycle and our overall health. But too much or too high in relation to progesterone is where the problems arise, and these problems can make our experience of endo worse. So what is oestrogen dominance? Oestrogen dominance occurs when the ratio of oestrogen to progesterone is too high, this can happen when progesterone is low, oestrogen is high or both! Excess oestrogen is when there is too much oestrogen circulating the body, and this would be likely cause oestrogen dominance, providing of course that progesterone isn’t also too high (which in my experience with clients at least, is generally less common). Why does oestrogen dominance occur? We deep dive into this topic in other interviews and episodes (so check the links below), but to give you an overview, here are some of the common causes: Stress Imbalanced blood sugar Gut health issues Deficiencies, such as zinc Heavy alcohol consumption Overburdened liver Xenoestrogens Whilst taking a holistic approach looking at all of these areas is advisable, eating certain foods can help your body to remove any old or excess oestrogen and adding these foods in can be a great way to get started with healing any imbalances. Here are seven of my favourite foods for alleviating oestrogen dominance with endometriosis: Dandelion root tea or coffee to help support the liver with clearing out old and excess oestrogen. Be careful that you’re not buying a caffeinated dandelion and coffee blend - we’re looking for dandelion alone. You can drink it as a herbal tea or buy it roasted, then grind and have as coffee! It makes a lovely black coffee or latte. Broccoli sprouts provide a big, concentrated dose of SGS (sulforaphane glucosinolate) , a plant compound that also helps the liver to detoxify oestrogen and break it down in a healthy way Cruciferous vegetables such as kale, broccoli, cabbage and Brussel sprouts aid oestrogen detoxification. The active compound in cruciferous veggies is a nutrient called I3C (indole-3-cabinol), which further breaks down into SGS (sulforaphane glucosinolate) and DIM (diindolymethane) and both play a big role in supporting the liver with oestrogen detoxification. In fact, these nutrients are so powerful that you may recognise them - they’re often found in oestrogen clearance supplements! Probiotic foods such as kefir, sauerkraut, kimchi and yoghurt help create a healthy gut microbiome and ensure that the bacteria which helps to eliminate oestrogen, the estrobolome, is well supported and that beta-glucuronidase, the enzyme that reactivates oestrogen (causing it to be reabsorbed into the blood stream), is prevented from getting too high. A caveat here is that if you have SIBO you may find probiotic foods aggravating. I would start slowly with one tablespoon and increase to tolerance over time. B6 foods such turkey, fish, seeds, nuts like pistachios, lentils, eggs, and a moderate amount of organic pasture-raised red meat helps to detoxify old and excess oestrogen and raise progesterone levels. Lignans from nuts and seeds, particularly pumpkin, sunflower, sesame and potentially flax (if you respond well to it) help bind and remove oestrogen. Flax can have weak oestrogenic effects, and is often recommended to help lower oestrogen dominance symptoms . However, I recommend being mindful here as I am not the only practitioner to have witnessed endo symptoms and oestrogen dominance symptoms worsening from flax, so I would just see how you personally respond. Having said that, lots of doctors, nutritionists and health coaches see an improvement, but just have an awareness when you try and if you try flax. Hopefully it works well for you! Listen and subscribe on iTunes, Stitcher, listen directly/download MP3 here or just listen below! Let's get social! Come say hello on Instagram, Twitter and Facebook or sign up to my newsletter. If you feel like you need more support with managing endometriosis, you can join Your EndoLife Coaching Programme. A 1-to-1 three month health and life coaching programme to help you thrive with endometriosis. To find out more about the programme and to discuss whether it could be right for you, email me at hello@thisendolife.com or visit my website. I am now offering one-off two hour sessions for those of you who aren’t quite ready for a 12 week coaching programme. This intensive deep dive session will kick start your journey to living and thriving with endometriosis and give you a plan that you can take forward and work on alone. Click here to find out more about the programme. My cookbook This EndoLife, It Starts with Breakfast is out now! Get 28 anti-inflammatory, hormone friendly recipes for living and thriving with endometriosis. Order your copy here. This episode is sponsored by my free “Endometriosis Symptom Tracker”. If you feel like you’re just in pain or tired all the time, and you can’t tell what’s making your endo better or worse, this tracker could help you begin to understand the subtle patterns in your endometriosis symptoms. As always, this guide doesn’t replace your medical treatment and is not intended to treat or cure endometriosis, but provides you with options that helped me to live well with endometriosis. Download here. This episode is sponsored by The Pod Farm. Learn all about how to start your own podcast with the complete course from The Pod Farm. Aimed at beginners, this course takes a simple and straightforward approach to planning, equipment buying, setting up, recording, editing and hosting your own podcast. With hours of audio and video materials, and downloadable guides and useful links, this multimedia approach aims to have something for every kind of learner. From now until April 15, newsletter subscribers get 20% off the course price. Visit www.thepodfarm.com to enroll or find out more This episode is sponsored by BeYou. Soothe period cramps the natural way with these 100% natural and discreet menthol and eucalyptus oil stick on patches and CBD range. Click here to find out more and to shop: https://beyouonline.co.uk Show Notes SIBO episodes Ep 99 with Dr Allison Siebecker Ep 97 My SIBO treatment plan Oestrogen dominance episodes Ep 104 Blood Sugar episodes Ep 88 Ep 81 Ep 66 Ep 55 Broccoli sprouts and cruciferous veg  Magdalena Wszelaki broccoli sprouts Changes in levels of urinary estrogen metabolites after oral indole-3-carbinol treatment in humans Indole-3-Carbinol (I3C) and its Major Derivatives: Their Pharmacokinetics and Important Roles in Hepatic Protection Estrobolome Alisa Vitti Histamine The 4-Phase Histamine Reset Plan B6 The Interactions between Vitamin B6 and Hormones Nutritional factors in the etiology of the premenstrual tension syndromes Dr Jolene Brighten B6 Lignans Dr Joelene Brighten on seed cycling and flax Lara Briden explains phytoestrogens

Bloating? Anxiety? Tearfulness? Painful breasts? If you experience any of these symptoms, you likely experience PMS in the lead up to your period. Even though PMS is very common, it doesn’t mean it’s just something we have to live with - especially when we’re dealing with endometriosis as well. In fact, PMS is caused by hormonal imbalances, often oestrogen dominance or excess oestrogen and sometimes low progesterone - and when we get these into balance, a lot of our endo symptoms ease too! So this week, I wanted to share with your seven foods that you can add in during your luteal phase (the phase after ovulation, before your period) that contain wonderful nutrients that have been shown to alleviate PMS and support healthy hormone balance… Leafy greens for magnesium, calcium and potassium. You guys must know by now how much I love magnesium! It helps to alleviate cramps, aids in oestrogen detoxification but also progesterone production and reduces bloating. Potassium additionally supports bloating, which is another bonus considering so many of you reach out to tell me this is one of your worse symptoms. Finally, in research calcium has been shown to help with PMS symptoms too! Add to smoothies, salads and whatever you’re having for dinner - think leafy greens with each meal. Nuts and seeds, particularly sunflower seeds, sesame (tahini is best here as sesame seeds are often too small to chew and pass through undigested) and pumpkin seeds. Nuts and seeds and these three in particular are rich in magnesium, and zinc which supports healthy progesterone levels and good levels of vitamin E, which has been shown to help alleviate period pain and PMS. Add nut butter to your porridge, overnight oats and smoothies and drizzle tahini over your veggies. Protein for B6, including organic free range and pasture raised chicken and turkey, organic grass-fed beef, fish, lentils and chickpeas. B6 helps to keep blood sugar levels stable (in turn, keeping hormones balanced and anxiety and fatigue at bay) and has actually been shown to reduce PMS and depressive symptoms, and is truly a crucial vitamin for healthy hormonal balance! Try a chickpea curry for dinner and perhaps wild caught fish or another animal protein at lunch with lots of veggies and some healthy complex carbs and fat. Sweet potatoes, squash and beetroot (and all other root veggies) actually help to raise serotonin levels in our brain thanks to their complex carbohydrate content. Our feel-good neurotransmitter, serotonin works closely with oestrogen during the first half of our cycle, and when oestrogen lowers in our second half our mood can take a bit of a hit - especially if our progesterone levels aren’t high enough. Eating root veggies with a good serving of protein and fat improve our mood, boost our energy and keep our blood sugar levels stable. Root vegetables also contain hormone loving B vitamins, calcium and magnesium - all great for balancing hormones and alleviating PMS. Try steaming and freezing root vegetables for smoothies or making up a lentil and beetroot salad. Peppers and other vitamin C rich foods like berries and broccoli can actually help to increase progesterone levels. Low progesterone levels can lead to PMS, anxiety, low moods, short cycles and pre-menstrual spotting. Try a salad of leafy greens, broccoli, peppers and lentils for a hit of vitamin C, magnesium and B6! Kidney beans, black beans, adzuki beans and other beans for B vitamins. B vitamins are some of the foundational nutrients behind healthy hormones - they ensure you’re making healthy amounts, keep oestrogen in check, support progesterone if it’s low and so much more that I’ll have to do a whole podcast on them. In short, they can help alleviate PMS symptoms by making sure any excess or old oestrogen is cleared out and that you have a healthy level of progesterone in your luteal phase. Try an Italian bean salad with rocket, pumpkin seed pesto, adzuki beans, borlotti beans, olives, red onion, tomatoes, pepper, artichokes and olive oil! Broccoli sprouts, broccoli and other cruciferous vegetables for healthy oestrogen elimination. Broccoli and broccoli sprouts contain DIM and sulforaphane which support the liver to break down oestrogen in a healthy way and therefore lowers any chance of PMS symptoms. Throw a big handful or half a cup of broccoli sprouts in your smoothies or on salads, and try adding cauliflower rice to your chickpea curry. Even just adding one or two of these foods in on a daily basis could make a difference! Try making a meal plan or some meal ideas with any of the above suggestions and track how your PMS symptoms over a few cycles to see if things change. Listen and subscribe on iTunes, Stitcher, listen directly/download MP3 here or just listen below! Let's get social! Come say hello on Instagram, Twitter and Facebook or sign up to my newsletter. If you feel like you need more support with managing endometriosis, you can join Your EndoLife Coaching Programme. A 1-to-1 three month health and life coaching programme to help you thrive with endometriosis. To find out more about the programme and to discuss whether it could be right for you, email me at hello@thisendolife.com or visit my website. I am now offering one-off two hour sessions for those of you who aren’t quite ready for a 12 week coaching programme. This intensive deep dive session will kick start your journey to living and thriving with endometriosis and give you a plan that you can take forward and work on alone. Click here to find out more about the programme. My cookbook This EndoLife, It Starts with Breakfast is out now! Get 28 anti-inflammatory, hormone friendly recipes for living and thriving with endometriosis. Order your copy here. This episode is sponsored by my free “Endometriosis Symptom Tracker”. If you feel like you’re just in pain or tired all the time, and you can’t tell what’s making your endo better or worse, this tracker could help you begin to understand the subtle patterns in your endometriosis symptoms. As always, this guide doesn’t replace your medical treatment and is not intended to treat or cure endometriosis, but provides you with options that helped me to live well with endometriosis. Download here. This episode is sponsored by The Pod Farm. Learn all about how to start your own podcast with the complete course from The Pod Farm. Aimed at beginners, this course takes a simple and straightforward approach to planning, equipment buying, setting up, recording, editing and hosting your own podcast. With hours of audio and video materials, and downloadable guides and useful links, this multimedia approach aims to have something for every kind of learner. From now until April 15, newsletter subscribers get 20% off the course price. Visit www.thepodfarm.com to enroll or find out more This episode is sponsored by BeYou. Soothe period cramps the natural way with these 100% natural and discreet menthol and eucalyptus oil stick on patches and CBD range. Click here to find out more and to shop: https://beyouonline.co.uk Show Notes Hormone balance with Nicole Jardim My blood sugar episode Lisa Hendrickson-Jack Fertility Awareness Method My FLO app Magnesium: Magnesium for oestrogen clearance The Association Between Serum Magnesium and Premenstrual Syndrome: a Systematic Review and Meta-Analysis of Observational Studies Magnesium--a new therapeutic alternative in primary dysmenorrhea Potassium: Potassium foods for bloating Calcium: A systematic review of the role of vitamin D and calcium in premenstrual syndrome Zinc: Zinc induced changes in the progesterone binding properties of the human endometrium Vitamin E: Evaluating the effects of vitamin D and vitamin E supplement on premenstrual syndrome: A randomized, double-blind, controlled trial B6: The Interactions between Vitamin B6 and Hormones Nutritional factors in the etiology of the premenstrual tension syndromes Dr Jolene Brighten B6 Vitamin C: Serum Antioxidants Are Associated with Serum Reproductive Hormones and Ovulation among Healthy Women Low progesterone B vitamins: Dr Joelene Brighten Broccoli sprouts:  Magdalena Wszelaki broccoli sprouts Changes in levels of urinary estrogen metabolites after oral indole-3-carbinol treatment in humans Indole-3-Carbinol (I3C) and its Major Derivatives: Their Pharmacokinetics and Important Roles in Hepatic Protection  

This episode, Dr. Jon and I use the journal article “Following the Roots of Kratom” published in 2015 by BioMed Research International as a jumping off point to talk about kratom history, human evolution and psychoactive plants, Terence McKenna’s “Stoned Ape” theory, and drug in religious cults . Plus, we answer listener mail about kratom […] The post 4. Journal Club with Dr. Jonathan Cachat: Human Evolution and Psychoactive Plants, Scratching the Surface of Kratom History, and Kratom Alkaloids first appeared on Kratom Science.

Trifulca Wrestling Media Presenta: En La Clara Con La Trifulca con Alex Torres, Gerardo Rodriguez y Omar Vázquez hablando sobre la avalancha de acusaciones de indole sexual que sacudieron la industria de la lucha libre a nivel global. ¡Sigue nos como Trifulca Wrestling Media! Facebook https://www.facebook.com/TrifulcaWrestling/ Instagram https://instagram.com/trifulcawrestlingmedia?igshid=11kmzu8xbvybt Twitter https://mobile.twitter.com/TrifulcaMedia YouTube https://www.youtube.com/channel/UCVZ0uJt-0skE-PkVGnmyTeA Spotify https://open.spotify.com/show/2Nki4huLPMwYftru08gFYV?si=BhUveS5kRvyTJU0ePNO2Ew Apple Podcast https://podcasts.apple.com/us/podcast/trifulca-wrestling-media/id1459553025 Anchor https://anchor.fm/trifulcawrestling #bookingsinsentido #somosindies #indiewrestling #wrestling #luchalibre #trifulcawrestlingpodcast #TWPInterview #TWNews #wrestlingpodcast #podcastenespañol #latinpodcast #noesmasdelomismo #prowrestler #prowrestling #trifulcawrestlingmedia #podcastlatino #latinpodcast #trifulcawrestlingnews #wwe #aew #boxing #mma #ufc #wrestlingnews #luchalibre #CWA

A look at the top medical headlines for the week of March 1, 2020, including: A study showing that a molecular switch governing chronic inflammation can be turned off. Then, a study shows that few of us are taking advantage of the great outdoors. And finally, doctors are reporting a strange, rare side effect of the active ingredient in Viagra—intensely blue-tinted vision.

This week - David Green reviews the role of a lesser noncompound INDOLE, a special compound present in many cruciferous foods, like broccoli, Kale, Cauliflower, Cabbage, and even our own gut bacteria and its protective role in protecting our livers against Non-Alcoholic Fatty Liver (NAFLD)that is reported to affect a staggering 33% of all UK adults.

Vertentes politicas estão se apropriando de princípios de cada individuo, assim dizendo que tais qualidades é por ser do lado x ou y.

Sono molte le cose che spero voi realizziate. Tuttavia, le vostre azioni e tutte le vostre vite non sono in grado di soddisfare completamente le Mie richieste, perciò non ho altra scelta se non quella di venire subito al punto e spiegarvi la Mia volontà. Dato che le vostre capacità di discernimento e di apprezzamento sono molto scarse, non sapete quasi nulla della Mia indole e della Mia essenza, pertanto è estremamente urgente che Io vi informi al riguardo. Non importa quanto tu abbia già capito in precedenza o se tu sia disposto a tentare di comprendere queste questioni, Io devo comunque spiegarvele nei dettagli. Questi argomenti non vi sono del tutto estranei, ma sembra che non capiate o non conosciate il significato in essi racchiuso. Molti di voi ne hanno solo una conoscenza confusa e, per di più, parziale e lacunosa. Al fine di aiutarvi a praticare meglio la verità, ossia a mettere meglio in pratica le Mie parole, penso che per prima cosa dobbiate venire a conoscenza di questi argomenti. Altrimenti, la vostra fede rimarrà vaga, ipocrita e piena dei segni esteriori della religione. Se non comprendi l’indole di Dio, ti sarà impossibile svolgere il lavoro che dovresti fare per Lui. Se non conosci l’essenza di Dio, ti sarà impossibile mostrarGli riverenza e timore, ma piuttosto solo incurante superficialità e prevaricazione e, per di più, incorreggibile blasfemia. Sebbene comprendere l’indole di Dio sia davvero importante e non si possa trascurare di conoscere la Sua essenza, nessuno ha mai esaminato o indagato a fondo questi argomenti. È evidente che tutti voi avete ignorato i decreti amministrativi che ho emanato. Se non comprendete l’indole di Dio, allora la offenderete facilmente. Tale offesa equivale a far incollerire Dio Stesso, e il risultato finale della tua azione diventa una trasgressione dei decreti amministrativi. Ora dovresti renderti conto che la comprensione dell’indole di Dio viene con la conoscenza della Sua essenza, e che comprendere l’indole di Dio equivale a capire i decreti amministrativi. Indubbiamente, molti dei decreti amministrativi accennano all’indole di Dio, ma al loro interno essa non viene espressa nella sua interezza. Ciò richiede che compiate un ulteriore passo avanti nella comprensione dell’indole di Dio.

Dio è un Dio vivente e, proprio come gli esseri umani si comportano diversamente in situazioni diverse, l’atteggiamento di Dio verso questi comportamenti differisce perché Egli non è un burattino, né è una parvenza. Arrivare a conoscere l’atteggiamento di Dio è una degna ricerca per l’umanità. Gli esseri umani devono imparare come, conoscendo l’atteggiamento di Dio, possano conoscere l’indole di Dio e un po’ per volta capire il Suo cuore. Quando giungi un po’ per volta a capire il cuore di Dio, non ti sembrerà che temere Dio ed evitare il male sia una cosa difficile da realizzare. Per di più, quando capisci Dio, è più difficile per te trarre conclusioni al Suo riguardo. Quando smetti di trarre conclusioni riguardo a Dio, è meno probabile che tu Lo offenda, e involontariamente Egli ti porterà ad avere conoscenza di Dio e a temerLo nel tuo cuore. Smetterai di definire Dio usando le dottrine, le lettere e le teorie che padroneggi. Invece, ricercando sempre le intenzioni di Dio in tutte le cose, diventerai inconsapevolmente una persona che è in sintonia con Dio.

A seguito di diverse migliaia di anni di corruzione, l’uomo è diventato insensibile e ottuso, un demonio che si oppone a Dio, a tal punto che l’insubordinazione umana nei confronti di Dio è stata documentata nei libri di storia e l’uomo stesso non è in grado di fornire un resoconto completo del suo comportamento ribelle; questo perché l’uomo è stato corrotto profondamente da Satana ed è stato indotto in errore da Satana in misura tale da non sapere più a chi rivolgersi. Ancor oggi, l’uomo continua a tradire Dio: quando Lo vede Lo tradisce, e anche quando non riesce a vederLo Lo tradisce. Vi è addirittura chi, malgrado sia stato testimone delle maledizioni e della collera divine, persevera nel tradire Dio. Per questo dico che la ragione umana ha smarrito la sua funzione originale e che anche la coscienza lo ha fatto. L’uomo che Mi è dato osservare è una bestia travestita da essere umano, un serpente velenoso, e per quanto cerchi di apparire commovente ai Miei occhi non sarò mai misericordioso nei suoi confronti, poiché non sa cogliere la differenza tra nero e bianco, tra verità e non verità. La ragione dell’uomo è fortemente insensibile, e malgrado ciò egli desidera ottenere benedizioni; la sua umanità è davvero ignobile, e tuttavia vorrebbe possedere la sovranità di un re. Ma di chi potrebbe essere re con una ragione simile? Come potrebbe stare su un trono con una simile umanità? Veramente l’uomo non ha alcun pudore! È un miserabile presuntuoso! A quanti tra voi desiderano ottenere benedizioni, consiglierei innanzitutto di procurarsi uno specchio e di guardare la loro brutta immagine ivi riflessa: hai ciò che è necessario per essere un re? hai il volto di chi potrebbe ottenere benedizioni? La tua indole non è cambiata nemmeno un po’ e non hai messo in pratica alcuna verità, eppure continui a desiderare un domani meraviglioso. Sei un illuso! Nato in tale sudicia terra, l’uomo è stato gravemente rovinato dalla società, ha subito l’influsso di un’etica feudale ed è stato istruito presso “istituti d’istruzione superiore”. Pensiero retrogrado, moralità corrotta, visione meschina della vita, ignobile filosofia, esistenza del tutto priva di valore, stile e abitudini di vita depravati: tutte queste cose sono penetrate seriamente nel cuore dell’uomo, e ne hanno gravemente minato e intaccato la coscienza. Il risultato è che gli esseri umani sono sempre più lontani da Dio e Gli si oppongono sempre più. Giorno dopo giorno l’indole umana si fa sempre più viziosa e non vi è nessuno che sia disposto a rinunciare a qualcosa per Dio, nessuno che voglia obbedirGli, neppure uno che abbia intenzione di cercare la Sua apparizione.

I. Il Regno di Dio è giunto sulla terra; ricca e piena è la persona di Dio. Chi può restar senza gioir? Chi può restar senza ballar? Oh Sion, innalza la tua bandiera per celebrare Dio. Canta la tua canzone di vittoria e diffondi il Suo santo nome. Moltitudini lodano Dio con gioia, infinite voci esaltano il Suo nome. Guardano alle Sue opere; ora il Suo Regno è giunto sulla terra. II. Creature sulla terra, ripulitevi, venite e fate offerte a Dio. Stelle, tornate al vostro nido nel cielo, mostrate il potere di Dio nei cieli. Sulla terra voci si innalzano e cantano, riversando amore infinito e riverenza sconfinata a Dio. Egli attento le ascolterà. Moltitudini lodano Dio con gioia, infinite voci esaltano il Suo nome. Guardano alle Sue opere; ora il Suo Regno è giunto sulla terra.

Vi è un detto di cui dovreste prendere nota. Ritengo che questo detto sia molto importante, perché a Me viene in mente innumerevoli volte ogni giorno. Perché? Perché ogni volta che mi trovo di fronte a qualcuno, ogni volta che ascolto la storia di qualcuno, ogni volta che sento parlare dell’esperienza di qualcuno o della sua testimonianza di fede in Dio, uso sempre questo detto per soppesare se tale individuo sia o no il tipo di persona che Dio vuole, il tipo di persona che Dio gradisce. Allora qual è questo detto? Adesso state tutti attendendo con ansia. Quando lo rivelerò, forse vi sentirete delusi perché alcuni da molti anni lo sostengono a parole. Ma quanto a Me, non l’ho mai sostenuto a parole. Questo detto risiede nel Mio cuore. Allora qual è questo detto? È “camminare sulla via di Dio: temere Dio ed evitare il male”. Non è una frase straordinariamente semplice? Eppure, sebbene sia semplice, chi ne ha sinceramente una comprensione profonda percepirà che ha grande peso; che è di grande valore per la pratica; che è linguaggio di vita con la realtà della verità; che è un obiettivo da perseguire per tutta la vita per coloro che cercano di soddisfare Dio; e che è una via da seguire durante l’intera vita per chiunque tenga conto delle intenzioni di Dio. Allora che ne pensate: questo detto è la verità? Ha questo tipo di significato? Forse alcuni ci stanno riflettendo sopra, cercando di capirlo, e altri ancora lo considerano con sospetto: questo detto è molto importante? È davvero molto importante? È davvero così necessario e degno di essere sottolineato? Forse ad alcuni questo detto non piacerà molto perché ritengono che prendere la via di Dio e distillarla in quest’unico detto sia una semplificazione eccessiva. Prendere tutto quello che Dio ha pronunciato e ridurlo a un unico detto: non significa forse rendere Dio un po’ troppo insignificante? È così? Può darsi che la maggior parte di voi non capisca pienamente il profondo significato alla base di queste parole. Anche se ne avete preso nota, non intendete trovargli un posto nel vostro cuore; vi limitate a trascriverlo e lo riguardate e ci rimuginate sopra nel tempo libero. Altri non si preoccuperanno nemmeno di memorizzarlo, tanto meno di farne buon uso. Ma perché esamino questo detto? A prescindere dal vostro punto di vista o da ciò che ne penserete, devo esaminarlo perché è estremamente pertinente a come Dio stabilisce il destino dell’uomo. Qualunque sia la vostra attuale comprensione di questo detto o comunque lo consideriate, vi dirò ugualmente: se qualcuno lo sa mettere in pratica adeguatamente e soddisfare il criterio di temere Dio ed evitare il male, sarà sicuramente un sopravvissuto, sarà sicuramente uno con un destino favorevole. Se non riesci a rispondere al criterio indicato da questo detto, si può dire che il tuo destino sia un’incognita. Perciò vi parlo di questo detto per la vostra preparazione mentale e affinché sappiate quale tipo di criterio Dio adotti per valutarvi. Come ho appena indicato, questo detto è estremamente pertinente alla salvezza dell’uomo da parte di Dio e a come Egli stabilisca il destino dell’uomo. Dove risiede questa pertinenza? Vi piacerebbe davvero saperlo, perciò ne parleremo oggi.

Prima di avere tue opinioni o deduzioni, devi innanzi tutto capire l’atteggiamento di Dio verso di te, cosa Dio ha in mente, e poi decidere se il tuo modo di pensare sia giusto o no. Dio non ha mai usato unità di tempo per stabilire il destino di una persona e non ha mai tenuto conto della quantità di sofferenza sopportata da una persona per stabilirne l’esito finale. Allora che cosa usa Dio come criterio per stabilire il destino dell’uomo? Usare unità di tempo per stabilire il destino di una persona: questo è ciò che più si conforma alle concezioni degli esseri umani. E vi sono anche coloro che vedete spesso, coloro che a un certo punto hanno dedicato molto, speso molto, pagato molto, sofferto molto. Questi sono coloro che, secondo le vostre opinioni, possono essere salvati da Dio. Tutto ciò che queste persone mostrano, tutto ciò che vivono è precisamente la concezione umana del criterio con cui Dio stabilisce il destino dell’uomo. Qualunque cosa crediate, non elencherò questi esempi uno per uno. In sintesi, se non è il criterio di pensiero di Dio, proviene dall’immaginazione dell’uomo ed è una concezione esclusivamente umana. Qual è la conseguenza dell’insistere ciecamente nella tua concezione e immaginazione? Ovviamente la conseguenza può solo essere che Dio ti disdegni. Questo perché ostenti sempre i tuoi meriti davanti a Dio, competi con Dio e disputi con Dio e non cerchi di comprendere veramente il Suo pensiero, né le Sue intenzioni e il Suo atteggiamento nei confronti dell’umanità. Procedere così significa onorare te stesso al di sopra di tutto, non onorare Dio. Tu credi in te stesso; non credi in Dio. Dio non vuole questo tipo di persona e non la salverà. Se tu riuscissi ad abbandonare un’opinione del genere e poi a rettificare quelle errate del passato; se potessi procedere secondo le richieste di Dio; cominciare a mettere in pratica, da questo momento in poi, la via di temere Dio ed evitare il male; riuscire a onorare la grandezza di Dio in tutte le cose; non usare le tue fantasie personali, i tuoi punti di vista o le tue convinzioni per definire te stesso, per definire Dio. Se invece cercassi le intenzioni di Dio sotto tutti gli aspetti, se conseguissi una consapevolezza e una comprensione dell’atteggiamento di Dio verso l’umanità e usassi il criterio di Dio per soddisfarLo, questo sarebbe meraviglioso! Vorrebbe dire che stai per intraprendere la via di temere Dio ed evitare il male.

Questo Dio in cui attualmente credete, avete mai pensato che tipo di Dio sia? Quando Egli vede una persona malvagia fare cose malvagie, disprezza questo fatto? (Lo disprezza.) Quando vede gli errori delle persone ignoranti, qual è il Suo atteggiamento? (Tristezza.) Quando vede persone che rubano le Sue offerte, qual è il Suo atteggiamento? (Le disprezza.) Tutto questo è ben chiaro, giusto? Quando vede qualcuno che è sconsiderato nella sua fede in Dio e non ricerca in alcun modo la verità, qual è l’atteggiamento di Dio? Non avete totale chiarezza su questo, vero? La sconsideratezza è un atteggiamento che non è un peccato e non offende Dio. Le persone ritengono che non dovrebbe essere considerato un errore grossolano. Allora quale pensi che sia l’atteggiamento di Dio? (Non è disposto a reagire.) Non è disposto a reagire: che atteggiamento è questo? È che Dio guarda dall’alto in basso queste persone, le disdegna! Dio tratta queste persone con freddezza. Il Suo metodo è accantonarle, non intraprendere alcuna opera su di loro, fra cui illuminazione, rivelazione, castigo e disciplina. Questo tipo di persona semplicemente non è incluso nell’opera di Dio. Qual è l’atteggiamento di Dio verso coloro che esasperano la Sua indole e offendono i Suoi decreti amministrativi? Totale disprezzo! Dio è estremamente incollerito da coloro che sono recidivi nell’esasperare la Sua indole! “Incollerito” è soltanto un sentimento, uno stato d’animo; non può rappresentare un chiaro atteggiamento. Ma questo sentimento, questo stato d’animo comporterà un esito per tale persona: colmerà Dio di totale disprezzo! Qual è la conseguenza di questo? È che Dio accantonerà tale persona e non le risponderà per il momento. Attenderà che venga selezionata durante la punizione. Che cosa implica questo? Tale persona ha ancora un destino? Dio non ha mai inteso assegnare un destino a una persona del genere! Allora non è forse normale che Dio al momento non le risponda? (Sì.) A cosa deve prepararsi adesso una persona del genere? Deve prepararsi a subire le conseguenze negative causate dal suo comportamento e dal male che ha fatto. Questa è la risposta di Dio a questo tipo di persona. Allora adesso dico chiaramente alle persone di questo tipo: non aggrappatevi più a convinzioni errate e non fatevi più pie illusioni. Dio non sarà tollerante all’infinito verso gli esseri umani, né sopporterà allo stesso modo le loro trasgressioni e la loro disobbedienza. Alcuni diranno: “Anch’io ho visto persone così. Quando pregano sono particolarmente toccate da Dio e piangono amaramente. Di solito sono anche molto felici; sembrano avere la presenza di Dio e la Sua guida”. Non dite queste sciocchezze! Piangere amaramente non significa necessariamente essere toccati da Dio o avere la presenza di Dio, tanto meno la guida di Dio. Se le persone fanno incollerire Dio, Egli le guiderà ugualmente? In sintesi, quando Dio ha deciso di eliminare qualcuno, di abbandonarlo, quella persona già non ha più un destino. Non importa quanto possa sentirsi soddisfatta di sé quando prega e quanta fiducia abbia in Dio nel suo cuore; questo è già irrilevante. La cosa importante è che Dio non ha bisogno di una fiducia del genere, che Dio ha già disdegnato tale persona. Anche come trattarla in seguito è irrilevante. Ciò che importa è che nel momento in cui tale persona fa incollerire Dio il suo destino è già stabilito. Se Dio ha deciso di non salvare una persona del genere, essa sarà abbandonata per essere punita. Questo è l’atteggiamento di Dio.

3. Dio fa dell’arcobaleno un simbolo del Suo patto con l’uomo (Genesi 9:11-13) “Io stabilisco il mio patto con voi, e nessuna carne sarà più sterminata dalle acque del diluvio, e non ci sarà più diluvio per distruggere la terra”. E Dio disse: “Ecco il segno del patto che io fo tra me e voi e tutti gli esseri viventi che sono con voi, per tutte le generazioni a venire. Io pongo il mio arco nella nuvola, e servirà di segno del patto fra me e la terra”. Ora diamo un’occhiata a questa parte delle Scritture, che racconta come Dio abbia fatto dell’arcobaleno un simbolo del Suo patto con l’uomo. Quasi tutti sanno cos’è un arcobaleno e hanno sentito alcune storie al riguardo. Per quanto concerne la storia dell’arcobaleno nella Bibbia, alcuni ci credono, altri la considerano una leggenda, mentre altri ancora non la ritengono affatto credibile. Sia come sia, tutte le cose che accaddero in relazione all’arcobaleno sono azioni che Dio compì in passato e che ebbero luogo durante lo svolgimento della Sua gestione dell’uomo. Sono state documentate accuratamente nella Bibbia. Queste testimonianze non ci dicono di che umore fosse Dio a quel tempo o quali fossero le intenzioni dietro le parole che pronunciò. Inoltre, nessuno è in grado di capire cosa abbia provato quando le disse. Tuttavia, il Suo stato d’animo riguardo all’intera questione viene rivelato tra le righe del testo. È come se i Suoi pensieri di quel momento balzassero fuori dalla pagina attraverso ogni Sua parola e frase.

Nello stesso periodo in cui visse Abramo, Dio distrusse una città, di nome Sodoma. Senza dubbio, molti conoscono la storia di Sodoma, ma nessuno è a conoscenza dei pensieri di Dio che fecero da sfondo alla distruzione della città. Per questo, oggi, attraverso i dialoghi tra Dio e Abramo riportati di seguito, impareremo a conoscere i Suoi pensieri di quel tempo, nonché la Sua indole. Adesso, leggiamo i seguenti passi della Scrittura. B. Dio deve distruggere Sodoma (Genesi 18:26) E Jahvè disse: “Se trovo nella città di Sodoma cinquanta giusti, perdonerò a tutto il luogo per amor d’essi”. (Genesi 18:29) Abrahamo continuò a parlargli e disse: “Forse, vi se ne troveranno quaranta”. E Jahvè: “Non lo farò”.

13. Gesù mangia il pane e spiega le Scritture dopo la resurrezione (Luca 24:30–32) E quando si fu messo a tavola con loro, prese il pane, lo benedisse, e spezzatolo lo dette loro. E gli occhi loro furono aperti, e lo riconobbero; ma egli sparì d’innanzi a loro. Ed essi dissero l’uno all’altro: Non ardeva il cuor nostro in noi mentr’egli ci parlava per la via, mentre ci spiegava le Scritture? 14. I discepoli offrono a Gesù del pesce arrostito (Luca 24:36–43) Or mentr’essi parlavano di queste cose, Gesù stesso comparve in mezzo a loro, e disse: Pace a voi! Ma essi, smarriti e impauriti, pensavano di vedere uno spirito. Ed egli disse loro: Perché siete turbati? E perché vi sorgono in cuore tali pensieri? Guardate le mie mani ed i miei piedi, perché son ben io; palpatemi e guardate; perché uno spirito non ha carne e ossa come vedete che ho io. E detto questo, mostrò loro le mani e i piedi. Ma siccome per l’allegrezza non credevano ancora, e si stupivano, disse loro: Avete qui nulla da mangiare? Essi gli porsero un pezzo di pesce arrostito; ed egli lo prese, e mangiò in loro presenza.

Durante il nostro ultimo incontro, abbiamo condiviso un argomento molto importante. Vi ricordate di cosa si trattava? Lasciate che ve lo ripeta. Il tema della nostra ultima condivisione era: l’opera di Dio, l’indole di Dio e Dio Stesso. Pensate sia un argomento importante? Quale aspetto è per voi più importante: l’opera di Dio, la Sua indole o Dio Stesso? Quale di questi temi vi interessa maggiormente? Di quale parte vorreste saperne di più? So che per voi è difficile rispondere a questa domanda, perché è possibile vedere l’indole di Dio in ogni aspetto della Sua opera e la Sua indole viene rivelata nella Sua opera sempre e in ogni luogo e, in realtà, rappresenta Dio Stesso; nel piano globale di gestione di Dio, la Sua opera, la Sua indole e Dio Stesso sono tutti elementi inseparabili l’uno dall’altro.

12. Gesù parla ai discepoli dopo la resurrezione (Giovanni 20:26-29) E otto giorni dopo, i suoi discepoli erano di nuovo in casa, e Toma era con loro. Venne Gesù, a porte chiuse, e si presentò in mezzo a loro, e disse: Pace a voi! Poi disse a Toma: Porgi qua il dito, e vedi le mie mani; e porgi la mano e mettila nel mio costato; e non essere incredulo, ma credente. Toma gli rispose e disse: Signor mio e Dio mio! Gesù gli disse: Perché m’hai veduto, tu hai creduto; beati quelli che non han veduto, e hanno creduto! (Giovanni 21:16-17) Gli disse di nuovo una seconda volta: Simon di Giovanni, m’ami tu? Ei gli rispose: Sì, Signore; tu sai che io t’amo. Gesù gli disse: Pastura le mie pecorelle. Gli disse per la terza volta: Simon di Giovanni, mi ami tu? Pietro fu attristato ch’ei gli avesse detto per la terza volta: Mi ami tu? E gli rispose: Signore, tu sai ogni cosa; tu conosci che io t’amo. Gesù gli disse: Pasci le mie pecore.

Ora parleremo della storia di Noè e di come si colleghi all’argomento dell’opera di Dio, dell’indole di Dio e di Dio Stesso. In questa parte delle Scritture, che cosa fa Dio nei confronti di Noè? Forse tutti voi qui seduti sapete qualcosa perché avete letto le Scritture: Dio fece costruire l’arca a Noè, poi usò un diluvio per distruggere il mondo. Fece costruire l’arca a Noè per salvare gli otto membri della sua famiglia, per consentire loro di sopravvivere, di diventare i progenitori della successiva generazione dell’umanità. Ora leggiamo le Scritture.

Per comprendere l’indole di Dio e Dio Stesso devi iniziare da qualcosa di molto piccolo. Ma da cosa? Anzitutto ho scovato alcuni capitoli della Bibbia. Le informazioni qui di seguito contengono versetti biblici, tutti riguardanti l’opera di Dio, l’indole di Dio e Dio Stesso. Ho scelto appositamente questi estratti come materiale di riferimento per aiutarvi a conoscere l’opera di Dio, l’indole di Dio e Dio Stesso. Qui li condividerò con voi per vedere che tipo di indole e di essenza Egli abbia rivelato attraverso la Sua opera passata, ma di cui le persone non sono a conoscenza. Forse questi capitoli sono antichi, ma l’argomento su cui stiamo comunicando è qualcosa di nuovo che le persone non conoscono e di cui non hanno mai sentito parlare. Alcuni di voi potrebbero trovare inconcepibile questo approccio: tirare in ballo Adamo ed Eva e tornare indietro fino a Noè non equivale a ripercorrere nuovamente gli stessi passi? Qualunque cosa pensiate, questi capitoli sono molto utili per la comunicazione su questo argomento e possono fungere da testi didattici o da materiali di prima mano per la condivisione di oggi. Quando finirò, avrete ormai compreso le Mie intenzioni dietro la scelta di questi brani. Forse coloro che hanno letto la Bibbia in precedenza si sono imbattuti in questi pochi versetti, ma potrebbero non averli capiti davvero. Diamo loro un’occhiata generale prima di passarli in rassegna più precisamente uno per uno.

Oggi comunicheremo su un argomento fondamentale, che è oggetto di discussione fin dall’inizio dell’opera di Dio ed è di vitale importanza per ogni singolo individuo. In altre parole, si tratta di un argomento in cui tutti si imbatteranno durante il cammino di fede in Dio, e che è necessario toccare. È un tema cruciale, inevitabile, da cui l’umanità non può discostarsi. A proposito di importanza, qual è la cosa più importante per chiunque creda in Dio? Alcuni pensano che sia la comprensione della Sua volontà; altri ritengono che sia nutrirsi maggiormente della Sua parola; alcuni credono che sia conoscere sé stessi; altri sono dell’opinione che sia sapere come trovare la salvezza attraverso Dio, come seguirLo e come soddisfare la Sua volontà. Per oggi accantoneremo tutte queste questioni. Di cosa discuteremo, allora? Di un argomento che riguarda Dio. È questo il tema più importante per ogni persona? Qual è il contenuto di una discussione che concerne Dio? Naturalmente, questo argomento non si può scindere dall’indole di Dio, dalla Sua sostanza e dalla Sua opera. Quindi oggi affrontiamo il seguente tema: “l’opera di Dio, l’indole di Dio e Dio Stesso”.

Che cosa fece Dio quando Giobbe venne assoggettato al suo tormento? Egli osservò, vigilò, e attese l’esito. Mentre osservava e vigilava, come Si sentiva? Ovviamente era in preda al dolore. Avrebbe tuttavia potuto pentirSi, a causa di tale dolore, di aver permesso a Satana di tentare Giobbe? La risposta è no! Non avrebbe potuto. Perché credeva fermamente che Giobbe fosse perfetto e retto, che temesse Dio e fuggisse il male. Egli aveva semplicemente dato modo a Satana di verificare la giustizia di Giobbe di fronte a Dio e di rivelare la propria malvagità e spregevolezza. Inoltre, si trattava di un’opportunità per Giobbe di dimostrare la sua giustizia, il suo timore di Dio e la sua fuga dal male di fronte al mondo, a Satana, nonché addirittura a coloro che seguono Dio. L’esito finale prova che il giudizio di Dio su Giobbe era corretto e scevro da errore? Giobbe sconfisse veramente Satana? A questo punto, leggiamo le parole archetipiche pronunciate da Giobbe, prova del fatto che egli aveva sconfitto Satana. Egli disse: “Nudo sono uscito dal seno di mia madre, e nudo tornerò in seno della terra”. Ecco l’atteggiamento obbediente di Giobbe nei confronti di Dio. Poi, egli dichiarò: “Jahvè ha dato, Jahvè ha tolto; sia benedetto il nome di Jahvè”. Le parole pronunciate da Giobbe provano che Dio osserva le profondità del cuore umano, che Egli è in grado di scrutare la mente umana, e dimostrano che la Sua approvazione di Giobbe è priva di errori, che quest’uomo che Dio approvò era giusto. “Jahvè ha dato, Jahvè ha tolto; sia benedetto il nome di Jahvè”. Queste parole sono la testimonianza che Giobbe rende a Dio. Furono tali parole comuni a intimorire Satana, a procurargli vergogna e a farlo fuggire in preda al panico, e che inoltre lo incatenarono e lo lasciarono senza risorse.

Dal principio fino ad oggi, solo l’uomo è stato capace di parlare con Dio. In altri termini, tra tutti i viventi e le creature di Dio, solo l’uomo è stato in grado di conversare con Lui. L’uomo ha orecchi che gli consentono di ascoltare e occhi che gli consentono di vedere; usa un linguaggio, idee proprie e libero arbitrio. Egli possiede tutto ciò che è necessario per ascoltare le parole di Dio, comprenderNe la volontà e accettarNe il mandato. Per questo Dio affida tutti i Suoi desideri all’uomo, giacché vuole renderlo Suo compagno, con gli stessi Suoi pensieri e in grado di camminare con Lui. Da quando ha avviato la Sua gestione, Dio ha atteso che l’uomo Gli donasse il suo cuore, in modo che Egli potesse purificarlo e preparalo, onde renderlo gradito a Dio e amato da Lui, per fare in modo che l’uomo temesse Dio e fuggisse il male. Dio ha sempre desiderato e atteso un tale esito. Nei resoconti della Bibbia, figurano persone simili? Esistono, cioè, nella Bibbia, esseri umani capaci di donare a Dio il loro cuore? Esiste qualche precedente, prima di questa era? Oggi continueremo a leggere le storie della Bibbia e a cercare di capire se ciò che fu compiuto da questo personaggio, Giobbe, abbia qualche legame con il tema “Donare il proprio cuore a Dio”, che stiamo attualmente esaminando. Cercheremo di capire se Giobbe fu gradito a Dio e amato da Lui.

L’opera della gestione di Dio e della salvezza dell’umanità inizia con l’offerta di Isacco da parte di Abramo Con la nascita di un figlio ad Abramo, la promessa che Dio gli aveva fatto fu adempiuta. Ciò non significa che il piano di Dio si fermò qui; al contrario, il grandioso piano di Dio per la gestione e la salvezza dell’umanità era solamente iniziato, e la concessione benedetta di un figlio ad Abramo fu solo il preludio del Suo piano globale di gestione. In quel momento, chi si sarebbe potuto immaginare che la battaglia di Dio con Satana era iniziata silenziosamente nell’istante in cui Abramo aveva offerto Isacco in sacrificio?

9. I miracoli di Gesù 1) Gesù sfama i Cinquemila (Giovanni 6:8-13) Uno de’ suoi discepoli, Andrea, fratello di Simon Pietro, gli disse: V’è qui un ragazzo che ha cinque pani d’orzo e due pesci; ma che cosa sono per tanta gente? Gesù disse: Fateli sedere. Or v’era molt’erba in quel luogo. La gente dunque si sedette, ed eran circa cinquemila uomini. Gesù quindi prese i pani; e dopo aver rese grazie, li distribuì alla gente seduta; lo stesso fece de’ pesci, quanto volevano. E quando furon saziati, disse ai suoi discepoli: Raccogliete i pezzi avanzati, ché nulla se ne perda. Essi quindi li raccolsero, ed empiron dodici ceste di pezzi che di que’ cinque pani d’orzo erano avanzati a quelli che avean mangiato. 2) La Resurrezione di Lazzaro glorifica Dio (Giovanni 11:43-44) E detto questo, gridò con gran voce: Lazzaro vieni fuori! E il morto uscì, avendo i piedi e le mani legati da fasce, e il viso coperto d’uno sciugatoio. Gesù disse loro: Scioglietelo, e lasciatelo andare. Tra i miracoli compiuti dal Signore Gesù, abbiamo selezionato solo questi due perché sono sufficienti per dimostrare ciò di cui vorrei parlare qui. Sono davvero sorprendenti, e molto rappresentativi dei miracoli da Lui compiuti nell’Età della Grazia. Anzitutto diamo un’occhiata al primo passo: Gesù sfama i cinquemila.

Il patimento sofferto da Giobbe non era opera di messaggeri inviati da Dio e non era stato provocato dalla mano di Dio. Invece, era stato causato personalmente da Satana, il nemico di Dio. Per questo, il livello di patimento sofferto da Giobbe fu profondo. Tuttavia, in quel momento Giobbe dimostrò, senza riserve, la sua quotidiana conoscenza intima di Dio, i principi sui quali erano basate le sue azioni giornaliere e la sua attitudine nei confronti di Dio, e questa è la verità. Se Giobbe non fosse stato tentato, se Dio non avesse inviato a Giobbe le prove, quando egli affermò: “Jahvè ha dato, Jahvè ha tolto; sia benedetto il nome di Jahvè”, si sarebbe potuto dire che Giobbe fosse un ipocrita; Dio gli aveva dato così tanti beni e quindi per forza benediceva il nome di Jahvè. Se, prima di essere assoggettato alle prove, Giobbe avesse detto: “Abbiamo accettato il bene dalla mano di Dio, e rifiuteremmo d’accettare il male?”, si sarebbe potuto affermare che stesse esagerando e che non avrebbe rinnegato il nome di Dio, visto che spesso era benedetto dalla Sua mano. Se Dio gli avesse mandato delle disgrazie, sicuramente egli avrebbe rinnegato il Suo nome. Tuttavia, quando Giobbe si trovò in circostanze che nessuno avrebbe potuto desiderare, o voluto vedere o sperimentare, che tutti temerebbero di sperimentare, circostanze che anche Dio Stesso non potrebbe sopportare di vedere, Giobbe fu ancora capace di tenersi stretto alla sua integrità: “Jahvè ha dato, Jahvè ha tolto; sia benedetto il nome di Jahvè” e “Abbiamo accettato il bene dalla mano di Dio, e rifiuteremmo d’accettare il male?” Di fronte alla condotta di Giobbe in queste circostanze, coloro che amano pronunciare parole altisonanti e disquisire su lettere e dottrine, rimangono ammutoliti.

A proposito di Giobbe Dopo aver appreso in che modo Giobbe affrontò le sue prove, la maggior parte di voi vorrà probabilmente conoscere altri dettagli su Giobbe stesso, in particolare sul segreto grazie al quale guadagnò la lode di Dio. Così, oggi parleremo di Giobbe! Nella vita quotidiana di Giobbe notiamo perfezione, rettitudine, timore di Dio e rifiuto del male Se vogliamo parlare di Giobbe, occorre iniziare con la sua valutazione, pronunciata dalla bocca stessa di Dio: “Non ce n’è un altro sulla terra che come lui sia integro, retto, tema Iddio e fugga il male”. Prima di tutto consideriamo la perfezione e la rettitudine di Giobbe.

Se ora vi dico che Giobbe è un uomo amabile, potreste non essere in grado di apprezzare il significato contenuto in queste parole e afferrare il sentimento che sta dietro al perché vi ho detto tutte queste cose, ma aspettate il giorno in cui avrete sperimentato prove uguali o simili a quelle di Giobbe, sarete passati attraverso le avversità, avrete sperimentato prove disposte da Dio per voi personalmente, avrete dato tutto, sopportato umiliazioni e avversità, per avere la meglio su Satana e rendere testimonianza a Dio in mezzo alle tentazioni, allora sarete in grado di apprezzare il significato delle parole che dico. In quel momento, sentirete di essere molto inferiori rispetto a Giobbe, quanto egli sia amabile, e degno di imitazione; quando sarà arrivato quel momento, comprenderete quanto sono importanti queste classiche parole pronunciate da Giobbe per chi è corrotto e vive in questi tempi, e comprenderete quanto sia difficile per le persone di oggi realizzare ciò che fu compiuto da Giobbe.

Alla fine delle prove di Giobbe, dopo aver ricevuto la sua testimonianza, Dio decise che avrebbe guadagnato un gruppo, o più di uno, di persone simili a lui, ma decise anche di non permettere mai più a Satana di attaccare o maltrattare nessun’altra persona utilizzando gli stessi mezzi con i quali egli aveva tentato, attaccato e maltrattato Giobbe, per scommessa con Lui; Dio non permise più a Satana di compiere tali atti contro l’uomo, che è debole, stolto e ignorante! Satana aveva già tentato Giobbe, ed era più che sufficiente! La misericordia di Dio non consente più a Satana di maltrattare nessuno in qualunque modo desideri. A Dio era stato sufficiente che Giobbe avesse sofferto la tentazione e il maltrattamento di Satana. Egli non gli permise mai più di compiere tali atti, perché la vita e tutto ciò che riguarda le persone che seguono Dio sono da Lui governati e orchestrati, e Satana non ha l’autorizzazione di manipolare a suo piacimento i prescelti di Dio, questo dev’essere ben chiaro! Dio Si preoccupa della debolezza dell’uomo, e comprende la sua stoltezza e la sua ignoranza. Sebbene, affinché l’uomo potesse essere completamente salvato, Egli lo abbia consegnato nelle mani di Satana, Dio non desidera mai vedere Satana trastullarsi con l’uomo come un giocattolo e maltrattarlo, e non vuole vederlo sempre soffrire.

Queste varie condivisioni hanno avuto un notevole effetto su ogni singola persona. D’ora in poi gli uomini potranno finalmente sentire realmente la vera esistenza di Dio e la Sua effettiva vicinanza. Pur credendo in Lui da molti anni, non hanno mai compreso davvero i Suoi pensieri e le Sue idee come fanno adesso, né hanno sperimentato veramente le Sue azioni pratiche come in questo momento. A prescindere che si tratti di conoscenza o di pratica effettiva, quasi tutti hanno imparato qualcosa di nuovo e raggiunto una comprensione superiore, e si sono resi conto dell’errore nelle proprie ricerche passate, della superficialità della propria esperienza, del fatto che troppe cose non sono in armonia con la volontà di Dio e che ciò che più manca all’uomo è la conoscenza della Sua indole.

Abbiamo appena parlato di tutta l’opera che Dio ha compiuto, della serie di cose che ha fatto per la prima volta. Ciascuna di loro attiene al Suo piano di gestione e alla Sua volontà, e anche alla Sua indole ed essenza. Se vogliamo comprendere meglio ciò che Egli ha ed è, non possiamo fermarci all’Antico Testamento o all’Età della Legge, ma dobbiamo proseguire lungo le fasi che Egli ha intrapreso nella Sua opera. Così, quando Dio mise fine all’Età della Legge e diede inizio a quella della Grazia, i nostri passi raggiunsero l’Età della Grazia, un’era piena di grazia e di redenzione, in cui Dio fece di nuovo qualcosa di molto importante per la prima volta. L’opera di questa nuova età fu un nuovo punto di partenza sia per Dio sia per l’umanità. Esso fu nuovamente un’opera che Dio svolse per la prima volta, qualcosa senza precedenti, inimmaginabile per gli uomini e per tutte le creature. È una cosa che ora è nota a tutti: fu la prima volta che Dio diventò un essere umano, che iniziò una nuova opera con le sembianze e l’identità di un uomo. Questa nuova opera indicava che Dio aveva completato quella dell’Età della Legge, che non avrebbe più fatto o detto qualcosa sotto la legge. Né avrebbe detto o fatto qualcosa sotto forma di legge, oppure secondo i suoi principi o le sue regole. Vale a dire che tutta la Sua opera basata sulla legge si interruppe per sempre e non sarebbe proseguita, perché Dio voleva cominciare una nuova opera e fare nuove cose, e ancora una volta il Suo piano ebbe un nuovo punto di partenza. Dunque Egli dovette guidare l’umanità verso una nuova era.

Ora daremo un’occhiata a una parabola raccontata dal Signore Gesù nell’Età della Grazia. 3. La parabola della pecorella smarrita (Matteo 18:12-14) Che vi par egli? Se un uomo ha cento pecore e una di queste si smarrisce, non lascerà egli le novantanove sui monti per andare in cerca della smarrita? E se gli riesce di ritrovarla, in verità vi dico ch’ei si rallegra più di questa che delle novantanove che non si erano smarrite. Così è voler del Padre vostro che è nei cieli, che neppure un di questi piccoli perisca.

(III) Cinque tipi di persone Per il momento concluderò qui la nostra comunicazione riguardo all’indole giusta di Dio. Passerò ora a classificare i seguaci di Dio in varie categorie, in base alla comprensione di Dio e alla conoscenza ed esperienza della Sua indole giusta. In questo modo saprete in quale stadio vi trovate, e qual è al momento la vostra attuale levatura. In termini di conoscenza di Dio e di comprensione della Sua indole giusta, gli stadi e i tipi di levatura a cui le persone appartengono possono essere approssimativamente suddivisi in cinque categorie. Questo argomento si fonda sulla conoscenza dell’unico Dio e della Sua indole giusta; pertanto, nella prosecuzione della lettura dovreste cercare di stabilire esattamente quanta comprensione e conoscenza abbiate riguardo all’unicità di Dio e alla Sua indole giusta, e poi usare questo dato per giudicare a quale stadio apparteniate realmente, quale sia il reale grado della vostra levatura e quale tipo di persona siate veramente.

Leggiamo ora i seguenti passi. 6. Il discorso della montagna 1) Le beatitudini (Matteo 5:3-12) 2) Il sale e la luce (Matteo 5:13-16) 3) La legge (Matteo 5:17-20) 4) L’ira (Matteo 5:21-26) 5) L’adulterio (Matteo 5:27-30) 6) Il divorzio (Matteo 5:31-32) 7) I giuramenti (Matteo 5:33-37) 8) Occhio per occhio (Matteo 5:38-42) 9) Amerai i tuoi nemici (Matteo 5:43-48) 10) Istruzioni sull’elemosina (Matteo 6:1-4) 11) La preghiera (Matteo 6:5-8) 7. Le parabole del Signore Gesù 1) La parabola del seminatore (Matteo 13:1-9) 2) La parabola della zizzania (Matteo 13:24-30) 3) La parabola del granello di senape (Matteo 13:31-32) 4) La parabola del lievito (Matteo 13:33) 5) Spiegazione della parabola della zizzania (Matteo 13:36-43) 6) La parabola del tesoro (Matteo 13:44) 7) La parabola della perla (Matteo 13:45-46) 8) La parabola della rete (Matteo 13:47-50) 8. I comandamenti

Il vero pentimento nel cuore dei Niniviti permette loro di ricevere la misericordia di Dio e modifica il loro destino Vi fu forse contraddizione fra il cambiamento d’idea da parte di Dio e la Sua ira? Niente affatto! Poiché la tolleranza di Dio in quel particolare momento aveva le sue ragioni. Quali ragioni? Quelle indicate nella Bibbia con le parole “ognuno si converta dalla sua via malvagia” e “abbandonare la violenza delle loro mani”. Questa “via malvagia” non consiste in pochi atti malvagi, ma nella fonte malvagia all’origine del comportamento umano. “Convertirsi dalla cattiva condotta” significa non commettere mai più certe azioni. In altri termini, non seguire mai più la via malvagia; il metodo, la fonte, lo scopo, l’intento e il principio delle azioni cambiano; non si ricorre mai più a quei metodi e principi per portare gioia e felicità al proprio cuore. Il termine “abbandonare” in “abbandonare la violenza delle loro mani” significa rinunciare o accantonare, rompere completamente col passato e non tornare più indietro. Quando la popolazione di Ninive abbandonò la violenza delle proprie mani, ciò provò, e fu in sé, un vero pentimento. Dio osserva l’esteriorità delle persone ma anche il loro cuore. Quando Dio vide chiaramente il vero pentimento nel cuore dei Niniviti, e costatò che essi avevano rinunciato alla loro via malvagia e abbandonato la violenza delle loro mani, cambiò idea. Vale a dire che la condotta e il comportamento di queste persone e certi loro modi di agire, nonché la vera confessione e il vero pentimento dei peccati nel loro cuore, indussero Dio a cambiare idea, a modificare le Sue intenzioni, a ritornare sulla Sua decisione e a non punirli e non distruggerli. Per questo la popolazione di Ninive ebbe un destino diverso, redimendo la propria vita e, allo stesso tempo, guadagnando la misericordia e la tolleranza di Dio, che, a quel punto, placò la Sua ira.

10. Il giudizio dei farisei su Gesù (Marco 3:21-22) Or i suoi parenti, udito ciò, vennero per impadronirsi di lui, perché dicevano: È fuori di sé. E gli scribi, ch’eran discesi da Gerusalemme, dicevano: Egli ha Beelzebub, ed è per l’aiuto del principe dei demoni, ch’ei caccia i demoni. 11. Gesù rimprovera i farisei (Matteo 12:31-32) Perciò io vi dico: Ogni peccato e bestemmia sarà perdonata agli uomini; ma la bestemmia contro lo Spirito non sarà perdonata. Ed a chiunque parli contro il Figliuol dell’uomo, sarà perdonato; ma a chiunque parli contro lo Spirito Santo, non sarà perdonato né in questo mondo né in quello a venire.

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Mensagem ministrada na Conferência Fiel de Pastores e Líderes 2018. Saiba mais em: ministeriofiel.com.br/pastores

Breast cancer affects 1 in 8 women. Men are not immune to this either as about 1% of breast cancers occur in males. This episode offers insight into a proactive educational nutritional approach. http://MitchelMD.com As always, this show is educational in nature and the listener must see their regular healthcare practitioner for advice and care.   Transcript (machine generated/unedited) [00:00] Welcome to the recharge podcast. This is October and breast cancer awareness month is upon us. I want to share a few statistics just to get things rolling and then I'm going to share a live interview with a patient. I recorded this a little bit ago and edited it out. It's an educational piece. Uh, the, the, uh, content, uh, don't be overwhelmed by the scientific part of it because we'll dive into the specifics of what it means for this particular patient. The takeaway point is that you really need to work hand in hand with your professional to address this issue. Sadly enough, one and eight women in the U s will develop some type of breast cancer over the course of their lifetime. The kicker here as this podcast is geared largely towards men, is that there are about 2,500 cases of invasive breast cancer diagnosed in men in 2018 alone. The risk remains about the same, about one percent or one in $1,000 for men having breast cancer. So I hope you find some value in this episode and as always a message if you have some concerns. And I hope you'll share it because undoubtedly this issue touches you or someone you know or love close friend or family member. [01:04] The title of this one hopefully grabbed your attention, Broccoli and breasts and obviously with breast cancer awareness month and wanted to shed some light on that issue. And, uh, this will be a little bit different episode. I actually have a live patient, um, someone to do the consult with, uh, regarding some breast cancer genetic risks. And so it's a, I'm trying to do my best to keep it a very limited or minimal in terms of the scientific terminology and jargon. I think you'll definitely get some value from it. But, uh, we just want to preface this that breast cancer not only affects women, but also men. There seems to be a rising percentage of men who are affected by breast cancer, somewhere between one and three percent depending on the, uh, the source of the data, but certainly is an issue that affects men as well. [01:50] And so the bottom line is that everybody, or a lot of people know about the breast cancer genes, Braca one and Braca two, that really comprises the minority of risk for breast cancer. Eighty percent comes from another set of genetic markers and these enzymes actually affect how a person processes estrogen estrogen, like many chemicals in the body can be converted into something beneficial or something detrimental. And if it's detrimental, we want to get rid of it. We want to pee it out or filter through the litter, liver or some other type of process to sort of clean it up and, um, minimize the risk of dangerous to the body. And so when a person has some abnormalities in terms of their machinery, their metabolic machinery, how their body processes things, that really can dramatically increase a risk of a condition. And for the purpose of today's podcast, talking about breast cancer. [02:42] And so, you know, depending on how many of these abnormalities show up for a given person or patient, the risks can really go, go up dramatically. And, uh, so in the example for today, this particular patient had five genes that had abnormalities and so her risk is substantially higher and there are specific things that can be done, terms of supplements, fish oil, dietary modifications, um, vitamin C, Glutathione, selenium, selenium, milk thistle, Indole, three carbinol. I've thrown a lot at you right now. I realize that we'll get into some more of that in the discussion in the recorded interview with one of my patients. So I hope you find some value in this. As always, you can reach out to me on twitter at Dr Mitchell and I love to answer your questions and if you're interested in obtaining a, some specific testing for yourself, I can kind of steer you in that direction as well. And so, um, sure to read the blog post that goes along with this, I give you some more information to some, some nuts and bolts that you really want to know in terms of breast cancer and trying to minimize risk. And so I hope you find this beneficial. And as always, I'd love to have a review on itunes from you. If you find some value in what I'm doing and sharing on the project you podcast and hope you have a fantastic week. So let's dive into the interview. [04:03] Thanks so much for uh, allowing me to record this. Um, we'll keep all your information confidential, but as you're well aware, it's breast cancer month and so just wanted to take a few minutes to go over your test. And the test is actually a test that measures how well your body metabolizes or processes estrogen, which is a huge impact in the risk of breast cancer. I think most women know about Braca one and two, which are sort of the genetic inherited breast cancers that everybody worries about from other family members, but that's really the minority of what, what comprises the risk of breast cancer. And so this test that you did, as you remember, was just a simple as swapping the cheek and it measured six different markers. Basically how well your body processes estrogen. I won't get into the specific genetic terms, but basically you can see from your test here, those are the six, six to eight that were measured in this particular test and so, um, the blue is normal, which means your body processes estrogen through that pathway normally and the pink are abnormal, which means that your body's enzymes may not be able to process certain components of estrogen into a, what we call favorable metabolite. [05:15] What that means is basically we can take part of estrogen and make it into something that is easy for your body to get rid of, whether you pee it out or detoxify it through the liver versus something that accumulates in the body and can potentially increase your risk for breast cancer. So that's sort of the test in a nutshell. I don't know if you have any, any specific questions about what you see on the report in front of you? [05:37] I guess, yeah, I do. I'm worried. I see that I have many variants detected and I just like to know if that means that I have breast cancer or, or I'm going to get breast cancer. [05:47] Sure. I mean, it's a, it's a, uh, a multifactoral questions. So let me get. The first thing is, are there other cancers in your family or do you have breast cancer in your family or other? [05:57] A breast and other. [05:59] Okay. And so, I mean, certainly there is a hereditary component of breast cancer. If you have a first degree relative that has breast cancer, that certainly increases the risk. And then there are certain syndromes where there are multiple cancers, for example, like a thyroid cancer combined with several other cancers in one person. So those are fortunately very rare. But to get to the, uh, answer your question is, um, just because you have these markers, that doesn't mean that you have breast cancer or that for sure you're going to get breast cancer. We know that, that, uh, people who have more abnormalities in their, their machinery, if you will, their metabolic machinery that their risk of breast cancer can go up significantly. And so the more abnormalities you have, a certainly a could increase your risk. But the real issue is just to kind of get the head of the, uh, the whole process is that the ability of, of things that you do to yourself and what you put into your body and really has a substantial impact on your risk. [06:57] And what I mean by that is just simple lifestyle things like what you eat, the kind of food you eat, whether you smoke or drink alcohol. I know it sounds like a simple approach to, uh, you know, potentially a fatal and devastating disease such as breast cancer, but it really kind of gets to the heart of the matter of what we call Epi genetics or another word that we throw around is nutrogenomix. And not to get all scientific, but really food is powerful in terms of using food as medicine. And so by changing what you put into your body, you really have the, the ability to impact these abnormalities in. So for example, you know, we, we sort of harp on our kids to eat green vegetables, but by consuming, for example, cruciferous vegetables, Broccoli as an example, you really have the power to sort of turn on and off some of these genetic abnormalities and so just by altering your diet based on specific abnormalities you see there, you really can can take a risk that might be as high as 13 fold and really scale that back down to something more along the lines of just a few percentage of increase risk so it doesn't wipe out the risk, but it certainly can help your body turn on and off some of these, these abnormalities or these abnormal pathways which can really improve your risk, decrease your risk, which is what it's called [08:15] about. As far as as diet goes. Is it, are there other lifestyle changes such as sleep or stress reduction or. [08:24] Yeah, absolutely. I mean straight sleep is critical. Sleep is sort of the starting block. Everybody wants to jump ahead to, you know, can I take a thyroid pill and tired or can I take a pill or a supplement or something to really fix everything, but if you're not sleeping properly, if your body's inflamed, your body can repair itself. And the, uh, effects of sleep deprivation are widespread and detrimental. It's not just fatigue, but also affects the way your body processes sugar and carbohydrates the way you're, you're a growth hormone is able to not repair the damage that occurs to your body throughout the day. And so sleep is sort of the cornerstone or the foundation of health that people often overlook. And then he kind of asked about specific, specific things. I mean, obviously not everybody loves Broccoli and there are some supplements, so there's one called dm or dim pro and it's got a long chemical name for it, but that's basically the active ingredient of Broccoli that you can take in a pill form, um, that sort of a, a proprietary name. [09:20] The other common name that you may have seen before, is it [inaudible] or Indole? Three carbinol. Most people just call it [inaudible]. That's just a simple supplement that you can take on a daily basis to really kind of shut off some of these abnormal pathways and to help your body process estrogen more effectively so that you can. You can turn an estrogen into something that's beneficial not to bore you with the chemistry of it, but when the estrogen passes through the body, it's shunted into different pathways, whether it's a a different chemical structure, there's a four, there's a 16 and I won't get into the specifics of the chemistry, but that really has a huge impact on whether or not this could be a potentially cancer causing substance or is it something that's beneficial and actually decreases your risk for cancer and also it also has an impact on your mental health in bone health as well. So I'm just a few simple changes in your diet can really have a dramatic impact on your longevity. Essentially. That's what this is all about, is avoiding cancer and in increasing your longevity. So I don't know if that makes sense or not. [10:25] Yeah, so basically this report is telling me that I have a higher risk factor for developing breast cancer, but there are things that I can do that can decrease my risk in my daily life as well. Well, [10:39] yeah, absolutely. I think that's sort of the key thing to know is is not that this test gives you a specific roadmap to avoid cancer, but it does point out some things that are problematic in your body. It's. It allows an individualized approach to your diet and your supplements to decrease your cancer risk and so by knowing that you can take steps to implement some of the changes, whether it's, you know, limiting your alcohol to no more than one drink a day. I'm really thinking hard about whether you're going to use a hormone supplementation or considering some people considering in vitro fertilization. The risk for that really dramatically increases in terms of breast cancer, particularly if you have some of these abnormalities where you get huge doses of a female hormones. The body doesn't process and properly and it's converted into the dangerous forms of estrogen which can dramatically increased risk of breast cancer. And other problems, so just knowing the information ahead of time really allows women to make some, some informed decisions about whether they're going to take birth control or if they're gonna use hormones with former hormones and uh, you know, certainly if there's family history of breast cancer, um, abnormal genetics certainly really want to consider and have an intelligent discussion with your fertility specialists, whether in vitro fertilization with the hormones is really the safest option for you. [11:58] I suppose that's something to consider too, when going through menopause and, and some, uh, hormone replacement during that time as well. [12:06] Absolutely. And do you know, depending on the training of the physician in classically trained physicians rely on Oral Estrogens, which has a functional physician, we know that that particularly is a, not the route to go. The topical estrogen is really the safest route in terms of trying to, a decreased risk of complications. Um, we know that oral estrogen can cause blood clots and increased heart disease and obviously very detrimental health effects. We haven't really found that with the topical estrogen. And the other side of the coin is it's always about balance. Estrogen and progesterone are the two primary female hormones and see a lot of women who don't sleep well at night, particularly when they get to the perimenopausal menopausal stage and oftentimes some supplementation with, with oral estrogen, sorry, oral progesterone, oral progesterone, which is safe, can really improve the quality of sleep. So a combination of some topical estrogen cream in oral estrogen is certainly an option to discuss with, uh, what's your personal physician regarding, you know, what's your desired effect is in terms of lifestyle. [13:11] And it also, again, the risk based on what we know about your genetics. So definitely important things to consider. And then the last point I wanted to bring up as we know that you have some abnormalities on your test here, and so what do you do next? And the next step would be to get the urine test, is to look at some of the metabolites of estrogen and see if you have abnormal amounts in these estrogens. It really needs to take the steps now to improve that if you ignore it in and just let the cumulative effects build up, at least in my opinion, the risk of breast cancer and other disasters outcomes certainly as a, as well stated in the literature. So I think just giving patients the information they need to really make some decisions about how they live, what they put in their body, and whether they're going to take supplements to really improve the metabolism and try to decrease some of the risks is, is just, you know, information is powerful. And uh, that was the purpose of this test for you. It's really kind of shed some light given your family history of breast cancer, a use of birth control pills in the past and uh, and some other factors. So, um, do you have any other questions about the report? [14:17] No, I think that pretty much goes over most of it. The questions that I didn't have. Thank you. [14:21] Yeah, and just the, I mean because the recommendation for you based on your report would be to either use dim or I C on a regular basis. Really take a hard look at very your vegetable cruciferous vegetable intake and the alcohol, a limitation you don't smoke, so that's a positive thing and there's some other supplements that, that, uh, we can talk about, uh, in the future that you might want to increase or may want to add to your diet and your regimen to really kind of improve sleep and other things that are, are critical. All right, you thank you so much for spending some time with me today. If you found value in this episode and the show, please share a review in itunes as it really helps the show get discovered. Please share your biggest takeaway, and as always, I want to help you answer the burning questions in your mind. So reach out to me. I mentioned Linda Dot com or on social media wherever you hang out. Make today incredible and I'll see you on the next episode of the recharge podcasts.

https://bengreenfieldfitness.com/detox2018 Well, I've been at it again folks: putting my mind and muscles through a brutal ringer for the sake of science.  In my recent post "", you learned how Men's Health magazine recently sent me on a 3 month global expedition to do everything a fella could possibly to do increase testosterone, size, orgasm quality, libido and a host of other manhood related parameters - including stem cell injections, acoustic sound wave therapy, red light blasting and beyond. Shortly after completing that article, I received my next writing assignment: outfit my pantry with an arsenal of the latest trendy hangover cures - from Oriental raisin extract hovenia dulcis to prickly pear concentrated extract to self-administered Myer's cocktail IV's - then engage in extreme alcohol hedonism and see what happens (). So, after all this brutality, I've decided to kick off 2018 by pushing the reboot button and cleaning up my entire system with a giant, scientifically proven detoxification mop, and I'm inviting you to join me. In this article, you'll learn why detoxification is not a myth, exactly why you should seriously consider detoxing (even if you live an ultra-clean lifestyle and don't necessarily treat your body as an N=1 guinea pig like I do), and how I'm personally going to detox using a relatively unique approach. Is Detoxification A Myth? A few years ago, The Guardian released an article entitled: ? In the article, the author says that: “...detoxing — the idea that you can flush your system of impurities and leave your organs squeaky clean and raring to go — is a scam. It’s a pseudo-medical concept designed to sell you things.” So is this true? Can you really not detox your body? As you go into the New Year, during which detox diets and claims are sure to surround you, it’s important to know the truth about detoxing. It’s important to begin with an understanding of what toxins actually are. No matter how “clean” you live your life, just about everybody shows some evidence of a buildup of toxins. When the Centers for Disease Control and Prevention (CDC) conducted the , they found some pretty shocking results. On average, the CDC’s report found 212 chemicals in people’s blood or urine, 75 of which had never before been measured in the U.S. population. The chemicals included: Acrylamide (formed when foods are baked or fried at high temperatures, and as a byproduct of cigarette smoke) Arsenic, found in many home-building products Environmental phenols, including bisphenol A (found in plastics, food packaging and epoxy resins) and triclosan (used as an antibacterial agent in personal care products such as toothpaste and hand soap) Perchlorate, used in airplane fuel, explosives and fireworks Perfluorinated chemicals, used to create non-stick cookware Polybrominated diphenyl ethers, used in fire retardants found in consumer products such as mattresses Volatile organic compounds (VOC’s), found in paints, air fresheners, cleaning products, cosmetics, upholstery fabrics, carpets, dry-cleaned clothing, wood preservatives, and paint strippers When you put all these together, these chemicals can potentially present a toxic burden to the human body, and (as the CDC has found) can accumulate in your body’s blood, urine and tissue — possibly one reason why the plastic-based versions of these chemicals are sometimes referred to as “obesogens,” due to the . While your body does actually have detoxification organs (your liver and kidney) that can process many of these chemicals and toxins, they can potentially cause medical problems if your liver and kidneys are not functioning properly or are overburdened with a poor diet.  for your blood and removing wastes and excess water from the body, it’s the liver that has an incredibly important job when it comes to detoxification. Along with filtering your blood to remove toxins, your . During phase 1, toxins are neutralized and broken into smaller fragments. Then, in phase 2 they are bound to other molecules, creating a new non-toxic molecule that can be excreted in your bile, urine or stool. But order for this liver detoxification to work properly, your body must have adequate nutrients. If not, , which can leave toxic substances to build up in your body. There are specific nutrients that support both pathways. For example: Phase 1: B-Vitamins (B2, B3, B6, B12, folic acid) Flavonoids, found in fruits and vegetables Foods rich in vitamins A, C and E (eg, carrots, oranges, wheat germ, almonds) Glutathione, found in avocado, watermelon, asparagus, walnuts, fresh fruits and veggies, and the nutrients n-acetylcysteine, cysteine and methionine. Branched chain amino acids, found in animal protein (dairy products, red meat, eggs and whey protein) Phospholipids, found in eggs, meats, organ meats, fish and soybeans Phase 2: Indole-3-carbinol, found in cabbage, broccoli, Brussels sprouts Limonene, found in oranges, tangerines, caraway seeds and dill seeds Glutathione, found in avocado, watermelon, asparagus, walnuts, fresh fruits and veggies. Fish oil Amino acids from protein  have demonstrated the  for supporting proper liver detox pathways. In addition, as you can learn in , Dr. Bryan Walsh has introduced the concept of a third "Phase 3" detoxification pathway. Now that you understand detoxification, let's delve into how detoxification products are actually supposed to work. The first claim in the article from The Guardian is based on a quote from , a professor of complementary medicine at Exeter University. He says: “...there are two types of detox: one is respectable and the other isn’t. The respectable one is the medical treatment of people with life-threatening drug addictions. The other is the word being hijacked by entrepreneurs, quacks and charlatans to sell a bogus treatment that allegedly detoxifies your body of toxins you’re supposed to have accumulated.” The article goes on to explain that when it comes to products that range from dietary supplements to smoothies and shampoos, not one of the manufacturers can actually define what they meant by detoxification, or name the toxins these products are supposed to remove. However, just because a manufacturer of — say — spirulina powder (a popular green powder found in the detox section of many health foods stores) can’t say how it works, doesn’t mean there isn’t scientific evidence for it’s potential to remove toxins from the body. For example, . It does this via a process called ion-exchange binding, and can . 100 micrograms (a very small amount) of spirulina hexane extract has been shown to . At a does of 250-500 milligrams per kilogram of body weight, spirulina has been shown to , and it has also been noted to , and . Granted, spirulina is one of the few molecules in existence that actually has a large body of evidence to support it’s detoxifying activity, but other compounds such as ,  and  have also been clinically proven to reduce heavy metal buildup. And while heavy metals are only one form of a toxin that can accumulate in your tissues, there is no doubt that science has proven that these toxins can indeed be removed via the use of these specific “detox” compounds found in nature. So when the article in The Guardian “guffaws” at the ideas of superfoods such as spirulina, I would actually beg to differ. Or take milk thistle extract, another popular detox or cleansing supplement. While the article in The Guardian would have you to believe there is no value whatsoever in consuming this type of nutrient,  that milk thistle actually protects and promotes the growth of liver cells, fights oxidation (a process that damages cells), and actually blocks toxins from entering the cell membrane. Silymarins, a group of antioxidants extracted from the seeds of milk thistle, have antioxidant properties several times greater than that of vitamins C and E, with . Milk thistle also helps to , which is necessary for phase 2 liver detoxification to be completed. As you can see from the two simple examples of spirulina and milk thistle, things aren’t quite as simple as painting with a broad brush and saying that detox supplements and diets simply don’t work. While the detox evidence for — say — cayenne pepper and maple syrup juice really doesn’t exist, evidence for other nutrients actually does exist. The article in The Guardian then goes on to address colon cleanses, noting that: “...proponents will tell you that mischievous plaques of impacted poo can lurk in your colon for months or years and pump disease-causing toxins back into your system. Pay them a small fee, though, and they’ll insert a hose up your bottom and wash them all away.” And also: “Some colon-cleansing tablets contain a polymerising agent that turns your faeces into something like a plastic, so that when a massive rubbery poo snake slithers into your toilet you can stare back at it and feel vindicated in your purchase.” When you think about it, the idea of toxins being somehow reabsorbed by your body as they sit in your colon actually makes some sense. After all, rectal suppositories are used to rapidly administer drugs — so if drugs can enter your bloodstream from your colon, it’s certainly possible that toxins could be entering too. However, your colon is equipped with several natural mechanisms to keep toxins from building up. For example: . . I personally suspect that if colon cleansing or enemas have any effect in making you feel like you have more energy or have been “cleansed”, it is more likely to do with an , along with , which can indeed improve digestion, have a laxative effect, relieve constipation and cause you to go to the bathroom. Sure, this could potentially make you feel better by allowing you to better digest your food, or to even pass some feces that may have built up over the past few days, but I’d have to agree with the article in The Guardian that there is no evidence that poo can simply sit inside you for years, slowly rotting and toxifying your body. So should you detox? Ultimately, as the article in The Guardian alludes to, your body has it’s own powerful methods of detoxification — and can activate these methods without the use of fancy diets or . These methods primarily come in the form of your liver and your kidneys. For example, your liver prevents pathogens from passing into your bloodstream, processes environmental toxins for safe removal, and helps to rid your body of excess nitrogen that build up from the breakdown of proteins and amino acids. Your kidneys filter blood, remove excess water, pass urea (which is a toxin that builds up as a byproduct of protein breakdown), and sends this all out of your body via your urine. So if you eat foods that support your liver and kidneys, or avoid foods that stress your liver and kidneys, you’re already detoxing every day — and theoretically, unless you’ve gone through something like a serious bout of alcoholism or heavy metal toxicity, you don’t really need any fancy herbal blends or colonic cleanses (at least, that's what I used to think. More on that in a second...as it may not be quite that simple). But first - to start simple indeed: for your liver, you can do things like avoid high amounts of omega-6 polyunsaturated fats from processed and packaged foods like canola oil and French fries, and instead eat those type of fats from fish, meat, seeds and nuts. You can avoid high amounts of fructose and sugar, limit alcohol, consume plenty of egg yolks (which contain choline that your liver uses to process fats), eat good, organic liver every now and then and . For your kidneys, you can limit , drink plenty of water, limit alcohol intake, and — if you are predisposed to renal issues — limit  (e.g. more than 200g/day of protein). So, as The Guardian article notes, many popular detox and cleansing diets probably feel beneficial very much in part because of what they eliminate. All the processed fats, high fructose corn syrup, alcohol, candy, soda, commercial meat and snack foods you’re eliminating on a detox diet are giving your liver and kidneys a chance to step up and do their normal detoxification duties, since they’re no longer overburdened with bad food and not enough micronutrients and minerals to support their normal function. But alas, the plot thickens, and it turns out that in our modern, post-industrial, radiated, metal-laden, polluted, glyphosate-sprayed, GMO-concentrated era, you may need to engage in a bit of better living through science and supplementation to truly detox. The Detoxification Plot Thickens So you eat a clean diet, take care of your liver and kidney's, and you don't need to detox, right? As I alluded to above, it's likely not that simple. See, when I interviewed Dr. Dan Pompa in the podcast episode “, he described a serious issue called “cellular toxicity” and explained why it is an underlying cause of numerous health issues, including gut problems, thyroid issues, sluggish metabolism, brain fog and much more. Once again, the cause of this modern phenomenon is not "woo-woo" or non-quantifiable toxins, but rather measurable physical compounds: plastics, phytoestrogens, metals, pharmaceuticals, herbicides, pesticides and all manner of other chemicals that can overwhelm our liver, kidneys and built-in detoxification system. And what’s especially unfair is that you and me (even when we’re living a clean lifestyle) have to get exposed to these toxins on a constant daily basis, whether from brake dust on car roads, or mercury from electronic equipment, or herbicides on the apples at our friend’s house, or estrogens in the shampoo at the hotel, or mold on the carpeting at the gym (don't even get me started on gyms - just read this two part series  on gym issue - and )…you get the idea. So even if your waistline and fat cell storage survived the holidays, the same might not be said for your brain, your lungs and the rest of your insides. In other words, over the past year, was your body ever exposed to over-processed and refined foods, chemical additives, antibiotics and pharmaceuticals, pesticides, herbicides, chlorinated water, artificial sweeteners or anything else that might remotely be consider “unnatural”? Did you drink many diet sodas? Eat much non-organic or farm-raised meat? Travel extensively? Chomp on fruits and vegetables without washing them? Get sick and have to get on a drug protocol? Engage in a few excessive nights of drinking? Get exposed to second-hand smoke? Spend much time around cleaning supplies? You get the idea. To make matters even worse, the world’s largest study on air pollution, just , found that when you breathe the average air in the average city (with all other variables held constant, such as eating healthy and exercising) you develop a huge risk for high blood pressure. How? In the study, the biological mechanisms for the adverse effect of air pollution on the functioning of the heart and blood vessels included: -Local and systemic inflammation… -Oxidative stress (a build-up of damaging molecules in the body)… -An imbalance in correct functioning of the nervous system… This also means that no matter how healthy you eat, how much you workout or how clean your water is, you’re still getting blasted with toxins from air pollutant every time you step into a city, or airport, or public gym, or just about anywhere else they aren’t using massive HEPA filters. How I’m Going To Detox This Year So why am I telling you all this? Frankly, everything that you've just read about is exactly I’m going to detox my entire body and brain beginning this February of 2018, and . That’s right, . And I’m not going to do just any ol’ detox like putting cayenne pepper into a nasty concoction or pushing giant grocery shopping carts full of random herbs through the supermarket. , these popular detoxes can actually release toxins from tissues such as fat cells and shove them into the brain, causing even more damage and serious brain and body repercussions that include permanent brain fog, weight gain, skin breakouts, mood disorders, and much more. Instead, I’m partnering up with one of the most brilliant detox minds on the face of the planet: the guy I mentioned earlier named , and Dr. Pompa's is going to walk us through the exact brain and body detox program that he’s studied and perfected for years. But I'm not going to stop there. I’m then going to combine Dr. Pompa's proven detox formula with my own exercise and biohacking protocols so that I can completely clean up my body without losing fitness by doing only, say, hot yoga and trampolining for weeks upon weeks. See, I don’t want to come out of my detox having lost my muscle or having to huff and puff whenever I climb a flight of stairs, so I’m pulling out all my fitness tricks that allow me to sculpt my body while I detox, without actually causing adrenal fatigue issues or ruining the detox protocol. I going to incorporate many of the similar modifications that I included in my detox last year, which you can , where you'll discover: -The 5 strategies I’m personally using to ensure I don’t lose fitness or muscle during my detox… -How fringe techniques like dry skin brushing, rebounding and infrared therapy can maximize the effectiveness of a detox… -The exact workouts I’ll be performing during my detox… -Whether or not you should use the dietary strategy of ketosis during a detox… -The best fasting strategy to use during a detox… -How meditation can fit perfectly into a detox program… -How oil pulling can assist with detox… -Why fermented foods are crucial during a detox… -The crazy, unique tea blends I’ll be using to accelerate my detox and wean myself off coffee… -And much more!  During that episode, you'll learn why I'm going to incorporate strategies such as: – – – – – – – – – – Now don't worry - if this all sounds crazy complex or if you don't have time to go back and listen to that podcast, then please understand that I've taken all the guesswork out of it for you, and out in an easy-to-understand and simple-to-use dashboard, training plan, and downloadable pdf's. You simply wake up each day, and do exactly what the plan says, and you can, of course, look forward at the beginning of each week to preview the entire program. No head scratching or laying awake at night worrying whether or not what you're doing is actually working (your detox even includes simply and easy-to-interpret urine strips to track your detoxification progress) The True Cellular Detox Challenge My “True Cellular Detox” Challenge begins on Monday, February 12, and  When you join, this means Dr. Pompa and I will walk you through every step of the detox, and you’ll get things like: 90-Days of Supplement Information and instructions Free Toxicity Testing To Measure Your Progress 20+ Hours of Detox Training 130+ Cellular Healing Recipes 90 Day Meal Plan with Grocery Lists 30 Delicious Smoothie Recipes Monthly Calls with me & Dr. Pompa Option to Include Advanced Strategies such as Intermittent Fasting, Ketosis, Diet Variation Burst Training Benefits & Explanations De-Bunking Fat Burning Myths Mindset Training Stress/Emotional Detox Strategies FAQ Board and Online Support  And much more! Whether you can’t seem to decimate a single fat cell and you’re experiencing brain fog, achy joints and serious lulls in energy or you want to blast your brain and body performance through the roof, look good naked, live as long as possible and feel amazing while doing it… …this challenge is the ticket: it will completely reboot your body. You can , but please be sure to get in on this detox soon because it will fill up fast and Dr. Dan and I want to be able to fit everybody in... ...the deadline to signup is by February 8th at 4pm! The same way you need instructions on how to detox the right way without harming your body, I need your help and your accountability to get me through this detox. Goodness knows that even though I’m a pretty healthy guy, I’m going to need a proper detox after both the holidays and an entire year of hard-charging, fast-living, daily post-industrialized world exposure, along with all that guinea-pigging. So let’s do this together. Do you have questions, thoughts or feedback for me about the 2018 True Cellular Detox challenge? Leave your comments at and I will reply! (and remember, you must sign up no later than February 8th at 4pm).

In today's episode, Dr Nirala Jacobi is in conversation with Dr Carrie Jones. Dr Jones is a Naturopathic Doctor and hormone specialist from Portland.  She has completed a two-year residency in advanced women's health, gynaecology and hormones, and has also completed her Masters of Public Health at the Grand Canyon University.  Dr Jones has been the medical director of two large integrative medical clinics in Portland and is currently the medical director of Precision Analytical, a laboratory that offers the DUTCH Profile.  She writes for multiple health websites and is featured in a range of health podcasts.   Topics discussed include Hormones and their relationship to functional digestive disorders. Digestive flares before a woman's period and why this can occur. How gut inflammation can affect hormones - for example by raising cortisol, raising estrogen, raising 5 alpha reductase, lowering dehydroepiandrosterone sulfate (DHEA-S), affecting the absorption of nutrients that comprise hormones. How lipopolysaccharides (LPS) and endotoxemia can impair and congest phase 1 and 2 liver detoxification pathways. Nutritional cofactors required to support smooth Catechol-O-methyltransferase (COMT) functioning, especially in light of COMT single-nucleotide polymorphisms (SNPs). Symptoms of estrogen dominance in men and women. Hormone patterns related to a dysfunctional gut microbiome. The estrobolome and how it can dictate how much beta-glucuronidase is produced, as well as how much dehydroepiandrosterone (DHEA) is released from the body. All about estrogen metabolism, the different metabolites that are produced, which ones are beneficial, and the liver pathways used for processing. Which estrogen metabolising pathways have associated cancer risk? The role of beta-glucuronidase in disrupting estrogen excretion. High toxic load patients and how hormone disruptors affect CYP enzymes and estrogen receptors. How can a patient show symptoms of estrogen dominance and yet their hormonal profiles be ok? Hint: If proliferative estrogen metabolising pathways favoured. When to intervene for hormonal balance when client presents with gastrointestinal issues? In light of high levels of beta-glucuronidase. How to test for beta-glucuronidase - fecal. What can we do about estrogen dominance? Support for Phase 1 Diindolylmethane (DIM) for clients favouring unhealthy 4-OH E1 or 16a-OH E1 pathways. Dietary adjustment to include Indole-3-carbinol (I3C) containing vegetables. Broccoli sprout powder for sulforaphane (to activate quinone reductase) Helps reverse the effects of going down unhealthy 4-OH E1 pathway. Glutathione support with N-acetylcysteine (NAC), and liposomal glutathione. Support for Phase 2 (COMT support) Magnesium Methylated B Vitamins Methionine Choline S-Adenosyl-L-Methionine (SAMe) Gut treatment Calcium D-glucarate to help lower beta-glucuronidase levels. Fibrous foods to bind free floating estrogen. Note: Broccoli and fibrous products not recommended in phase 1 of SIBO treatment. When to use binders in detoxification treatment. Progesterone Why can people with bloating potentially be progesterone deficient? Progesterone cream in second half of the cycle versus vitex supplementation - what age groups are appropriate to each? DUTCH testing - what is the difference between all the testing available? Saliva tests - free hormones. Blood tests - hormones are bound to sex hormone binding globulins or other carrier proteins. DUTCH test - free hormones and metabolites. Cortisol and cortisone - how to assess beyond an adrenal stress index, the difference between both forms, and why the body may have a pattern of inactivating cortisol into cortisone. How to balance cortisol to cortisone ratio? The role of licorice (Glycyrrhiza glabra) Flatlining cortisol and its role as a marker for chronic infection, its association with an increased risk for cancer, and increased risk for autoimmune issues. The cortisol awakening response and how it works with the thymus gland to destroy autoimmune antibodies. The link between chronic infections and low cortisol, and how to address. All about DHEA and DHEA-S Counters stress Energy, bone health, neurotransmitter balance, sex drive, muscle development. 7-keto DHEA - what is this? Supporting DHEA via adrenal support. When and when not to test hormone levels. Endometriosis and digestive disturbance due to adhesions, inflammation, and excess estrogen. New developments in the hormonal testing field. IBS symptoms around the period and why this may be. The importance of structural alignment for uterine and intestinal health. Therapy to address structural alignment - visceral manipulation, pelvic massages, and bodywork. Flaxseeds Helpful for estrogen dominance Raises SHBG (note that flaxseeds preferentially bind testosterone - so care in women who are struggling with testosterone levels) Soy The role of fermented soy for hormonal balance in menopause. Is soy estrogenic, or does it downregulate the proliferative estrogen pathway? Dr Carrie Jones' 2018 hormone education plans for practitioners and patients.   Resources Dr Carrie Jones Precision Analytical for Dutch Testing A5M conference 2017 Dr Chris Shade Podcast - detoxification Dr Walter Crinnion - environmental medicine

Today’s podcast is on cancer prevention. Sadly, cancer is one of the more common subjects that comes up for our wellness co-host Fon. On today’s show we will discuss some of the ways you can go about preventing it. The calls we have gotten this week are from people with family histories of cancer. We’ll hear from Cathy who has a family history of breast cancer as well as Ed in Philadelphia who grew up in a house with second hand smoke, we’ll also take a call regarding symptoms of prostate cancer. We will discuss the kinds of foods, herbs and vitamins you can take to increase your red and white blood cell counts and also go over some pretty amazing mushrooms that have been associated with cancer prevention. If you have questions regarding herbal nutrition or are looking for a natural solution to something that ales you, please give us a call at 512 853 9005 and we will try our best to answer your question. This show is sponsored by Dr. Vim's Herbal Nutrition. Dr. Vim's herbal formulas are designed for men and women to mental focus, physical energy and stress reduction. They use only filler free high potency botanical extracts. ensuring that every batch delivers a full dose of the most powerful phytonutrients on the planet.     SHOW NOTES:   Facts and Statistics on Cancer for Men and Women:   1 in 2 people in the USA will get cancer at some point in     their life. Most Common Cancers Among Women Breast cancer Lung cancer Colorectal cancer Leading Causes of Cancer Death Among Women Lung cancer Breast cancer Colorectal cancer Most Common Cancers Among Men Prostate cancer Lung cancer Colorectal cancer Leading Causes of Cancer Death Among Men Lung cancer Prostate cancer  Colorectal cancer Liver cancer   Foods to Avoid: GMO's Hydrogenated Oils  Microwave Popcorn Processed Meats Diet Foods with Artificial Sweeteners Artificial Flavors and Colors Refined Sugar Refined White Flour Farm Raised Fish Foods Sprayed with Glyphosate or other Pesticides and     Fungicide.   Lifestyle Habits: Maintain Alkalinity  Antioxidant intake  Reduce systemic inflammation Detoxification Limit exposure to environmental toxins Sunlight and Exercise  Reduce stress  Get Sleep   Eating Habits - The American Diet is full of unhealthy fats, refined sugars, bleached flour, artificial ingredients and colors, farmed fish, and toxic sources of meat.  Focus on getting a diet full of minerals, vitamins, antioxidants, and healthy fats.   Leafy Green Vegetables - Rich in vitamins, minerals, antioxidants and enzymes, yet very low in calories, fats, sodium and other toxins.  Cruciferous Vegetables - Source of vitamins C and K, the powerful antioxidant Glutathione, and estrogen metabolizing compounds DIM, Calcium D Glucarate, and Indole-3 Carbinol.   Berries - The antioxidant content of most berries are very high, making them some of the most powerful foods in the world.  Berries are known to be a great source of proanthocyanidin antioxidants, which help to decrease free radical damage.  Brightly Orange-Colored Fruits and Veggies - an excellent source of vitamin A, fiber, and carotenoid antioxidants.  Healthy Fats - Most of the fats found in the American diet are toxic and cause damage to our cells.  However, 60 percent of our brain and nervous system are made up of fatty acids. Omega 3's support inflammation response, mood, and focus, and help us maintain a healthy heart and help to protect our cells. Examples of healthy fats: Hemp Oil Chia Oil Flax Oil Algae Oil Fish oil Extra Virgin Olive Oil Nuts and Seeds - Chia seeds, hemp Seeds, and flax seeds are and excellent fiber, omega-3 fatty acids and a range of important minerals. Hemp seeds and pumpkin seeds contain healthy fats Magnesium and Zinc.  Brazil nuts are the best source of selenium. Sprouted nuts have the widest range of benefits. Fresh Herbs and Spices -Try to incorporate organically grown, immune boosting spices like turmeric, ginger, oregano, and garlic into your recipes and vegetable juices. Fermented Foods - Cultured foods are a great source of probiotics.  Probiotics are beneficial microorganisms that help digest food, get nutrients into the system, and boost immune function. A healthy gut is imperative to staying healthy.  It is believed that up to 80% of the immune system is in the gut! Medicinal Mushrooms - Potent immune-enhancers that have been used to fight cancer for centuries. Reishi, cordyceps and maitake in particular can improve immune function and cell regeneration. Green Tea - Not only is it a great pick me up, green tea is an excellent source of cancer fighting antioxidants that are several times more potent than Vitamins C and E called polyphenols. Garlic - We mention Garlic under spices, but keep in mind that it’s known to boosts white blood cell count.   Important Health Factors: Healthy Blood Cells Red Blood Cells and Oxygenation -  We have to have enough red blood cells to carry oxygen. Warburg won the nobel prize in 1931 after figuring out that once a cell has less that 60% of the oxygen it needs cancer occurs. Important because cancer cells are Anaerobic and proliferate through burning glucose. Healthy cells are Aerobic and thrive with sufficient oxygen Best way to build red blood cells is by consuming chlorophyll - it's the closest thing to hemoglobin in the plant world. co-factors that help build red blood cells Vitamin B6  Vitamin B9 Vitamin B12 Vitamin A  Iron Copper CoEnzymeQ10 - nutrient vital for the production of energy in the mitochondria. Powerful antioxidant that is also used in the mitochondria to transport oxygen. CoQ10 must be there for your cells to produce energy using oxygen because it transports oxygen to where it needs to be. White Blood Cells - cells are produced in the bone marrow, and typically work as part of the immune system to fight off bacterial and viral infections. We have to have white blood cells to fight off invaders and to combat cancer cells. Vitamin D3  Vitamin D insufficiency and deficiency are linked to poor immune functioning, which may translate to low white blood cell counts. Clinical research shows that vitamin D can help prevent cancer best when you acquire about 50–70 nanograms per milliliter daily. Get 20 minutes of sun exposure every day between 10 a.m. and 2 p.m. with 40 percent of your entire body exposed to the sun or take an oral supplement containing around 5,000 to 10,000 IUs of D3 every day.  Zinc  Linked with the production of white blood cells According to The American Cancer Society, studies have shown that zinc levels in blood and inside white blood cells are often lower in patients with certain types of cancer. Selenium The University of Maryland Medical Center states that selenium can help build up white blood cells and move them around. Some studies also indicate that selenium may help prevent some infections. Another study indicated that when the elderly takes both zinc and selenium supplements, their immune systems responded better to the flu vaccine than those who took placebo. Vitamin B9 (Folate) The body needs folate to make white blood cells.  A deficiency of folate can also lead to anemia, which is a low level of red blood cells.  Vitamin C an immune enhancer that helps white blood cells perform at their peak and quickens the immune system's response. Omega 3 Fatty Acids Help combat inflammation and helps make white blood cells.   Adaptogens boost Immune Function and modulate white blood cell count.   Astragalus Root Helps boost white blood cells University of Texas found that Astragalus Root enhanced the immune system’s ability to identify bacteria, viruses, and even cancer cells.   Cat's Claw Modulates the white blood cell count - if the white blood cell count is too low, it will increase it, and if it’s too high, it will decrease it. According to herbalist Maya Cointreau, "cat’s claw increased the ability of white blood cells to find and eradicate foreign micro-organisms. It also increases the body’s production of T-cells, helping to fight infection more effectively.”  Reishi Mushroom Source of polysaccharides that have been shown to better activate Natural Killer cells reducing cancer metastasis. Natural Killer cells are lymphocytes that seek out tumors. Reishi also has been shown to assist in slowing the growth of tumors as well as prompting programmed cell death in malignant cells.  Maitake Mushroom Stimulates Natural Killer cell activity in cancer patients. Believed to suppress tumor growth and to trigger malignant cell death through its specific immune-enhancing methods.   Agaricus Blazei Murill Activates macrophage and interferon immune activity leading to tumor shrinkage and stopping metastasis. Reduces chance of future cancer occurrences.  Also shown to decrease the side effects of chemotherapy or certain types of cancers.   Turkey Tail Studies show that it increases Natural Killer cell activity towards tumor detection and eradication. Soursop (Graviola) -  Found to be stronger at killing cancer cells than chemotherapy.  Studies show compounds found in Soursop kill cancer cells, but do not harm healthy cells. Nutrients that Support Breast Health  Zinc Selenium Omega 3's Vitamin D3 Vitamin A Vitamin E B6, B9, B12   Estrogen Metabolizing Nutrients DIM (diindolylmethane) – Found in all cruciferous vegetables, such as broccoli, cabbage, and kale. DIM forces estrogen to break down into a non-cancer promoting type of estrogen in the liver Calcium D-glucarate -Also found naturally in cruciferous vegetables, as well as fruits, such as apples, oranges, and grapefruit.  It aids the liver in the production of glucuronic acid, which binds to "bad" estrogens and deactivates them. Indole-3 Carbinol - Also found in cruciferous vegetables, Indole Carbinol has been found to benefit estrogen metabolism. Remember that it's the "bad" estrogen that is cancer promoting.  Aromatase Inhibitors - Antioxidants that block aromatase, an enzyme that helps to create estrogen. There's a type of bad estrogen is believed to fuel breast cancer cell growth. Examples:  Grape seed extract Chrysin - biofavaniod compound found in propolis, honey, and passionflower. Parsley Cruciferous Vegetables   Nutrients that Support Prostate Health: Zinc Selenium Omega 3's Vitamin D3 Vitamin A Vitamin E B6, B9, B12   Herbs that Support Prostate Health: Saw Palmetto -This herb has shown to reduce prostate inflammation and enlargement CBD oil (Cannabadiol) - cannabinoids have been found to inhibit the growth of this ID-1 gene and to return cancerous cells back to healthy cells. Prostate cancer patients have high levels of the ID-1 gene. Lycopene - An antioxidant found to prevent and even reverse prostate cancer as well as prostate enlargement. This is the red pigment contained in foods such as tomatoes and watermelon. Stinging Nettle Root - Studies have shown it to reduce the symptoms associated with prostatitis.   Nutrients that Support Lung Health: Zinc Selenium Omega 3's Vitamin D3 Vitamin A  Vitamin E B6, B9, B12   Herbs that Support Lung Health: See list of Medicinal Mushrooms above See Astragalus Root above

In this podcast, Dr. Meaghan Kirschling discusses natural approaches to fertility and reproductive health.  Reproduction is a complicated system, and infertility issues affect many women.  However, we do not talk about all the aspects of reproduction enough, and this podcast focuses on starting that important conversation. In this podcast, we want to discuss fertility and provide some examples of individuals that Dr. Meaghan has helped with fertility.    IN THIS PODCAST, WE WILL ADDRESS THE FOLLOWING ASPECTS OF FERTILITY  Healthy oils Take high-quality fish oil 6-8 grams of fish oil supplementation a day Take coconut oil, avocado oil, olive oil, walnut oils, etc Take out processed fats, vegetable oils, and trans fats REMEMBER OUR REPRODUCTIVE ORGANS LOVE HEALTHY FATS AND OILS Stress Reduction Find good coping mechanisms to decrease the production of cortisol and stress hormones This can be emotional, mental, physical or chemical stress Incorporate meditation Recommend acupuncture and essential oils Insulin and Blood Sugar Control Insulin and blood sugar is so important for the reproductive organs Berberine can be very helpful in this case Take out dairy Mucus producing and can interfere with hormones Estrogen Detox to take you out of estrogen dominance Estrogen is the hormone of womanhood Progesterone is the hormone of motherhood Estrogen will help you create eggs, but you can’t prepare the uterus and grow a baby without proper progesterone Need to support the release of estrogen with phase 1 and phase 2 detoxification and calcium d-glucarate. Also, important to incorporate DIM and Indole 3-carbinol either through supplementation or the cruciferous vegetables of broccoli, Brussel sprouts, kale, cauliflower, etc. Castor Oil Packs with heat are also beneficial  

Aphrodisiacs come from the old Greek Goddess , Aphrodity, who was the goddess of love, beauty, pleasure and procreation.Spinach : Very high in zinc, and it is a very important mineral for test production. deficiency in zinc can cause a lot of of health woes in which Erectile Dysfunction is one of them ( if you don’t know what ED means, it’s basically when a man not being able to keep an erection firm enough for sexual intercourse)Spinach contains an ingredient known as indole-3-carbinol. Indole-3-carbinol is responsible for stopping the production of estrogen in men. Men who produce very little estrogen tend to have leaner muscles and higher testosterone production which means killer libido and sex drive.Oysters: Extremely high in zinc, which is known as the sex booster mineral to begin with, especially amongst men. Oysters contain more zinc than any other food on the planet. But also exceptionally high in Omega 3 Fatty acids, and can help to regulate the inflammatory effects of many of today’s foods to begin with. Omega 3 fats also help with healthy cholesterol mobilization which can help boost testosterone levels, which are truly good for both men and women, we both have them.The old myth about eating oysters only in months that end in “R” is false, you’re perfectly safe, you just get better flavor in the fall and winter months.Chill Peppers: for my friends who don’t like spicy stuff you may not like this… Chilli Pappers has a component called Capsaicin Have you ever noticed a natural high when eating chilies and the burning sensation you get after ? Capsaicin promotes the release of chemicals that can raise your heart rate and trigger the release of endorphins that give you a natural high, which pumps that libido ( some people always say Spicy food, spicy bedroom, probably why most of the Spicy food consuming countries have such high fertility and what not)Watermelon: Even though watermelon is more than 90% water, the remaining 10% contains a super potent phytonutrient called “citrulline.” This converts to an amino acid called arginine which relaxes blood vessels and increases blood flow. Those of you that take any pre-workout supplements or anything like that, arginine is what is often in them to help you get more blood flow during your workout. Ultimately, increased blood flow can result in easier arousal for both men and women. And for men that may suffer from erectile dysfunction, this can help significantly as well. Not to mention, watermelon wouldn’t be too bad of a pre-workout snack!Figs : this is an amazing one, this fruit's been around for centuries and totally should be in the superfood category. fun fact, It was Cleopatra’s favorite fruit. Ancient greeks valued it more than gold as some points... because of it’s benefits, besides lowering cholesterol, good for diabetics since it contains a lot of potassium which helps regulate sugar in the blood, prevention of coronary heart disease (high in Omega 3 & 6 )BUT for our topic today, this is an amazing one, ancient world was recommending figs to correct many sexual dysfunctions, like sterility, Erectile dysfunction, Stamina...etc what we do in the mediterranean area is soaking 2-3 figs in organic milk and eating them in the morning. and sometimes even drinking the milk or the water where it was soaked at.Saffron: Saffron, the spendy little spice, is actually quite the aphrodisiac, and one of the few that has stood the test to serious scientific scrutiny. Many scientists feel that aphrodisiacs are merely a placebo effect, but saffron is one that clearly works from a physical standpoint! Saffron contains 3 specific anti oxidants that help with sex drive, crocin, crocetin, and safranol. Studies actually showed significant blood flow to the reproductive areas shortly after consuming saffron. You can actually add saffron to your tea and make a nice little aphrodisiac drink to set the mood right! What’s funny is that Cleopatra was ALSO known for using saffron! I guess she was quite sexually active!Dates: another ancient fruit that has been around for thousands of years. besides its deliciousness, dates is great source of vitamins and minerals (calcium, iron, phosphorus, sodium, potassium, magnesium, and zinc, vitamin A, K niacin...etc) helps with constipation, health bone, Allergies, Reducing LDL cholesterol levels which leads to healthy heart.so studies has shown that dates beneficial for increasing sexual stamina. Also dates contains high level of estradiol and flavonoid, these components increase the sperm count and motility. also promotes the increase of testicular size and weight.Pesto: It looks like the old disney cartoon of Lady and the Tramp had it right when it came down to romantic spaghetti! Pesto is show to be great for sexual health because of a couple reasons. For one, they contain the appropriate polyunsaturated fats to help with cholesterol production, but they also generally contain pine nuts. And next to oysters, pine nuts are one have one of the highest concentrations of zinc of any food! And like we covered before, zinc is definitely a powerful aphrodisiac. But don’t overdo it on pesto, because it is usually very high in salt and in calories, and pine nuts are so potent, you really only need about a tablespoon or two. Try to make it with spaghetti squash instead.Avocados : Testical tree as it was called by Aztics, it contains high amount of vitamin B6 and vitamin E, which increases hormone production, it is also great source of monounsaturated fats which are amazing for a healthy heart.They also contain vitamin B6 (a nutrient that increases male hormone production) and potassium (which helps regulate a woman's thyroid gland), two elements that help increase libido in both men and women.LDL cholesterol doesn’t just clog arteries – it leads to erectile dysfunction and a lack of flow in the downstairs department, too. Penn State University researchers found men with high intakes of monounsaturated fat – avocado – had lower LDL cholesterol and more testosterone.Eggs:I love how eggs are making a solid comeback lately! They used to be deemed so unhealthy, but now people are really starting to realize that they aren’t bad for you; they’re good for you! The reason eggs are so good for your sexual health is because of the high levels of that vitamin B-6 once again, but they are also specifically good for male testosterone levels. So if you or someone you know may be suffering from a loss of libido, having a couple of whole eggs every morning can help the natural sterols form to establish new testosterone conversion! Make sure when you get your eggs that you’re getting cage free and organic, not just cage free, because it doesn’t mean too much!Maca: Is known by many as Peru’s natural Viagra. This natural root has been known throughout Peru’s history as a sex enhancing root passed down by the Inca. According to research, the maca plant is used by the Peruvian culture to increase strength, stamina, energy, fertility and libido. I started adding it to my morning smoothies and have Maca lattes. Learn More at Organicfit Blog

The efforts and projection of Clorinda Matto de Turner's works go beyond the issue of indigenous people, women or religious aspects. They are fundamental to the construction of the imaginary, where the identity and future of Latin-American leadership is formed by their own history, from Pre-Columbian times to the present. Her initial premise in novels such as Aves sin Nido, Tradiciones Cuzqueñas, Indole o Herencia shows us a difficult social reality in XIX century Perú. During her exile in Argentina (1895), until her death (1909) is when her vision extends beyond borders and the result is discourses that cover aspects of the foundation of a Latin American nation, emerging in a new concept of the mother-land. In this imaginary, she criticizes the perpetuation of patriarchal tradition and seeks to reform progress in a way that men and women participate equally. Her essays, discourses and diaries in Boreales, miniaturas y porcelanas (1902) for example, emphasized the role of women who are bearers of great social change, women who write and educate. She called them Workers of Progress or Intellectual Workers. It is necessary to refer to the previous effort of Juana Manuela Gorriti, one of Matto's friends and mentors. She is important in the history of both Argentina and Perú because of her work associated with women representation in the building of a nation. This work focuses on Juana Manuela Gorriti’s stories from Sueños y Realidades (1875) where nation-building drama is narrated. Gorriti is a protagonist of this drama as well, during Manuel de Rosas' regime in Argentina. This essay will also show her journey while she was exiled, and her educational and intellectual work in Perú promoting literary circles and transnational intellectual networking.

Im Rahmen der Dissertation wurden Neue Metall-mediatisierte und Metall-katalysierte selektive Synthesen mit Alkinen untersucht. Dabei stand die Entwicklung möglichst atomökonomischer Methoden zur Darstellung synthetisch interessanter Produkte aus Alkinen im Vordergrund. Dies konnte in vier Projekten realisiert werden: 1) Synthese allylischer Nitrile Aliphatische Nitrile 10 konnten in Gegenwart katalytischer Mengen Cäsium-tert-butoxid in N-Methylpyrrolidinon (NMP) intermolekular an Alkine 1 addiert werden. Die entsprechenden allylischen Nitrile 11 wurden in guten bis sehr guten Ausbeuten und mit hervorragenden Regio- und cis / trans-Selektivitäten erhalten(Schema 76). Schema 76. Basen-katalysierte Vinylierung von Alkinen mit Nitrilen. Nichtaktivierte Alkine und Nitrile zeigten in dieser Reaktion noch recht niedrige Reaktivitäten. Deshalb wäre es wünschenswert, neue Katalysatoren bzw. Additive zu testen, um auch diese Substrate erfolgreich in allylische Nitrile zu transformieren. 2) Synthese substituierter Indole Ausgehend von 2-Ethinyl-anilinen 96 war es gelungen, durch eine Basen- mediatisierte 5-endo-dig-Zyklisierung 2-substituierte Indole 97 unter sehr milden Bedingungen in moderaten bis sehr guten Ausbeuten zu erhalten (Schema 77). Schema 77. Basen- mediatisierte Indolsynthese ausgehend von 2-Ethinyl-anilinen. Besonderer Vorteil gegenüber literaturbekannten Indolsynthesen stellt die große Anwendungsbreite aufgrund der hohen Toleranz gegenüber funktionellen Gruppen dar. Außerdem ist keine Aktivierung des Anilins durch eine elektronenziehende Gruppe (z.B. CF3CO) am N-Atom notwendig und statt des teuren Palladiums kann eine vergleichsweise kostengünstige Base eingesetzt werden, wobei die Verwendung der Base in stöchiometrischen Mengen als einziger Nachteil anzusehen ist. Weiterhin war es möglich, mit dieser Methode erstmals den selektiven Einbau der Brom- Substituentendes Alkaloids Hinckdentin A (124) zu erreichen(Schema 78). Schema 78. Selektive Zyklisierung als Schlüsselschritt in der Hinckdentin A Teilsynthese. Ziel weiterer Arbeiten sollte natürlich die Vervollständigung der Naturstoffsynthese sein. Der enantioselektive Aufbau des Lactamringes stellt dabei die größte Herausforderung dar. 3) Synthese von Propargylaminen Durch die Verwendung von Kupfer(II)-bromid als Katalysator können Propargylamine 162 aus Aminalen 160 und terminalen Alkinen 161 synthetisiert werden (Schema 79), wobei alsR 1 Schema 79. Kupfer-katalysierte Propargylaminsynthese aus Alkinen und Aminalen. Durch den Einsatz weiterer Aminale, z.B. heterocyclische Aminale, könnte eine noch höhere Diversität erzielt werden. Im Hinblick auf eine mögliche enantioselektive Reaktionsführung gilt es, neue Liganden zu untersuchen, um höhere Reaktionsgeschwindigkeiten und Enantiomerenüberschüsse zu erzielen. 4) Enantioselektive Synthese von Propargylaminen Nachdem eine racemische Synthese Alkyl-substituierter Propargylamine aus Enaminen 200 und Alkinen 225 entwickelt wurde, ist es gelungen, die Reaktion auch enantioselektiv durchzuführen (Schema 80). In Gegenwart von CuBr und (R)-(+)-QUINAP (185) können enantiomerenangereicherte Propargylamine, die sowohl von pharmazeutischem als auch von synthetischem Interesse sind, mit bis zu 90 % ee in guten Ausbeuten erhalten werden. Schema 80. Kupfer/QUINAP-katalysierte enantioselektive Synthese von Propargylaminen. Ferner konnte demonstriert werden, dass sich die erhaltenen Propargylamine zu primären und sekundären Aminen entschützen lassen. Somit steht erstmals eine katalytische Methode zur Erzeugung enantiomerenangereicherter Propargylamine zur Verfügung. Eine Ausweitung dieser Methode auf funktionalisierte Enamine ist wünschenswert. Weiterhin könnten diastereoselektive Additionen an chirale Enamine bzw. unsymmetrische trisubstituierte Enamine von Interesse sein. einziges Nebenprodukt ein leicht zu entfernendes sekundäres Amin gebildet wird.

Sat, 1 Jan 1994 12:00:00 +0100 http://epub.ub.uni-muenchen.de/4094/ http://epub.ub.uni-muenchen.de/4094/1/032.pdf Wanner, Klaus Th.; Weber, Ulrich Wanner, Klaus Th. und Weber, Ulrich (1994): Oxazolo[3′,2′ :1,2]pyrido[3,4-b]indole und [1,3]-Oxazino [3′,2′ :1,2]pyrido[3,4-b]indole durch eine einfache Kondensationsreaktion von 3,4-Dihydro-β-carbolin mi

Mon, 1 Jan 1979 12:00:00 +0100 http://epub.ub.uni-muenchen.de/3638/ http://epub.ub.uni-muenchen.de/3638/1/019.pdf Nagakura, Naotaka; Rüffer, Martina; Zenk, Meinhart H. Nagakura, Naotaka; Rüffer, Martina und Zenk, Meinhart H. (1979): The biosynthesis of monoterpenoid indole alkaloids from strictosidine. In: Journal of the Chemical Society, Perkin Transactions 1: pp. 2308-2312. Chemie und Pharmazie

Sun, 1 Jan 1978 12:00:00 +0100 http://epub.ub.uni-muenchen.de/3626/ http://epub.ub.uni-muenchen.de/3626/1/020.pdf Rüffer, Martina; Nagakura, Naotaka; Zenk, Meinhart H. Rüffer, Martina; Nagakura, Naotaka und Zenk, Meinhart H. (1978): Strictosidine, the common precursor for monoterpenoid indole alkaloids with 3 α and 3 β configuration. In: Tetrahedron Letters, Vol. 19, Nr. 18: pp. 1593-1596.