Podcasts about ODN

SYNOPSIS:This is a recording of one of our free, live Eventbrite sessions, where Ali Mezey was joined by Jane Peterson, PhD - and you, our audience - for a live, honest, body-centered conversation about the real work of being in relationship.(Yes, this episode includes live audience questions!)Together, we explore how our bodies carry old relational patterns - what Jane calls the "social soma" - and how these hidden imprints can shape the way we love, fight, and stay (or don't stay) connected.We talk about why love alone isn't always enough to align two people's lives, and why asking deeper, more honest questions early on matters so much.Jane shares practical ways to stay close even when life pulls you in different directions: evolving agreements, repairing after hurt, setting shared goals, and building intimacy that grows with you.We touch on marriage, infidelity, and non-traditional relationships with honesty and warmth, offering grounded advice for navigating real-world love.Whether you're partnered, single, or somewhere in between, this conversation will leave you with new ways to understand yourself, your relationships, and the deep intelligence of your body in all of it.To be an angel to the podcast, click hereTo read more about the podcast, click hereMORE ALI MEZEY:Website:  www.alimezey.comPersonal Geometry® and the Magic of Mat Work Course information:www.alimezey.com/personal-geometry-foundationsTransgenerational Healing Films: www.constellationarts.comMORE JANE PETERSON:Website: www.human-systems-institute.comContact: humansystemsinstitute@gmail.comBIO:Jane Peterson, PhD, is the co-founder and executive director of the Human Systems Institute, Inc. She is the originator of Somatic Imaging and the somatic-resonance approach to constellation work. Her work is internationally respected for being tailored to meet the high learning demands of adult professionals. She was a faculty member at the International Intensive Workshop on Systemic Resolutions in Bernreid, Germany for 9 years. Jane is an INFOSYON certified Master Trainer and has served as an advisor and author for the Knowing Field journal. She has taught systemic constellation work in Asia, South America, South Africa, Mexico, Canada, Europe, and the U.S.In 2005, she organized the first U.S. Conference in constellation work. Her Institute offers trainings in Somatic Imaging and systemic constellation work, including training in organizational constellations. The institute is currently offering it's seventeenth year of training programs.Jane started her professional career as an engineer and manager in a high tech firm (the first woman engineer hired into her department) and knows first-hand the demands placed on leaders in the corporate environment. In the course of becoming a constellation facilitator, she has also been a professional ceramic sculptor and ran her own fine arts studio, Laughing Bones, Inc.Jane is a master practitioner of Neuro-linguistic Programming, a Certified Clinical Hypnotherapist, a Certified Professional Behavioral Coach and a member of the American Counseling Association, VOIS, OHA, and ODN. She has studied Process Oriented Psychology with Arny Mindell and Max Schupbach, Group Dynamics with Michael Grinder, Peruvian energy healing with Don Amèrico Yàbar, Attachment and Trauma work with Dan Siegel and Diane Poole Heller, a Psycho-biological Approach to Couples Therapy with Stan Tatkin (Level 2), Coordinated Management of Meaning with Barnett Pearce, and continues to learn with other research-driven leaders in the fields of personal and social evolution. She holds a doctorate in Human and Organizational Systems from Fielding Graduate University, and has been a post-doctoral fellow of the Institute for Social Innovation.OTHER RESOURCES, LINKS AND INSPIRATIONS:Essential Skills for CouplesAdapting Systemic Constellations to OrganizationsHuman-Systems-InstituteBurt Hellinger: “caring for desire”Elaine Debutant: compatibility is actually an achievement of love, not a precondition.”SOCIAL SOMA - our body is shaped by our social relationshipsLALAGE SNOW:  We Are the Not Dead - photographerStan Tatkin - safety in relationship = taking care of each other. The Social BiomeTerry Real - The Social EcosystemEsther Perel: Mating in CaptivityArny Mindell, Sitting in the Fire: Large Group Transformation Using Conflict  and DiversityScience of TouchingEllyn Bader, the Initiator/Inquirer processStan Tatkin, In Each Other's Care: A Guide to the Most Common Relationship Conflicts and How to Work Through ThemTerry Real,

SYNOPSIS:In this episode, Ali is joined by world-renowned Family Constellation Work facilitator and trainer (and Ali's Constellations mentor), Jane Peterson, PhD, to discuss our bodies, minds, and systemic consciousness. They explore the multi-dimensional concept of embodiment, emphasizing that the body exists and interacts in a complex web of relationships. Peterson shares her insights on Family Constellation Work, systemic thinking, and her experiences in permaculture and organizational consulting. They discuss the importance of relational dynamics, belonging, and the interplay between individual and collective systems. Ali and Jane also touch upon the relevance of micro-skills in achieving mastery in embodied practices and collaborative relationships, while highlighting the common issues in modern communication frameworks. This episode offers a profound look at how brilliant us bodies are and how understanding these systems can lead to greater personal and societal harmony.To be an angel to the podcast, click hereTo read more about the podcast, click hereMORE ALI MEZEY:Website:  www.alimezey.comPersonal Geometry® and the Magic of Mat Work Course information:www.alimezey.com/personal-geometry-foundationsTransgenerational Healing Films: www.constellationarts.comMORE JANE PETERSON:Website: www.human-systems-institute.comBIO:Jane Peterson, PhD, is the co-founder and executive director of the Human Systems Institute, Inc. She is the originator of Somatic Imaging and the somatic-resonance approach to constellation work. Her work is internationally respected for being tailored to meet the high learning demands of adult professionals. She was a faculty member at the International Intensive Workshop on Systemic Resolutions in Bernreid, Germany for 9 years. Jane is an INFOSYON certified Master Trainer and has served as an advisor and author for the Knowing Field journal. She has taught systemic constellation work in Asia, South America, South Africa, Mexico, Canada, Europe, and the U.S.In 2005, she organized the first U.S. Conference in constellation work. Her Institute offers trainings in Somatic Imaging and systemic constellation work, including training in organizational constellations. The institute is currently offering it's seventeenth year of training programs.Jane started her professional career as an engineer and manager in a high tech firm (the first woman engineer hired into her department) and knows first-hand the demands placed on leaders in the corporate environment. In the course of becoming a constellation facilitator, she has also been a professional ceramic sculptor and ran her own fine arts studio, Laughing Bones, Inc.Jane is a master practitioner of Neuro-linguistic Programming, a Certified Clinical Hypnotherapist, a Certified Professional Behavioral Coach and a member of the American Counseling Association, VOIS, OHA, and ODN. She has studied Process Oriented Psychology with Arny Mindell and Max Schupbach, Group Dynamics with Michael Grinder, Peruvian energy healing with Don Amèrico Yàbar, Attachment and Trauma work with Dan Siegel and Diane Poole Heller, a Psycho-biological Approach to Couples Therapy with Stan Tatkin (Level 2), Coordinated Management of Meaning with Barnett Pearce, and continues to learn with other research-driven leaders in the fields of personal and social evolution. She holds a doctorate in Human and Organizational Systems from Fielding Graduate University, and has been a post-doctoral fellow of the Institute for Social Innovation.OTHER RESOURCES, LINKS AND INSPIRATIONS:Robert Keegan: In Over Our Heads, The Mental Demands of Modern LifeSarah Peyton's Books  Amber Gray's episode: Trauma and the Body: Regulation, Restoration, & The Patience of WhalesYour Resonant Body with Sarah Peyton: Brain Circuits, Childhood Contracts & Reconceiving AddictionMerlin Sheldrake's Entangled Life: How Fungi Make Our Worlds, Change Our Minds and Shape Our FuturesJordan Klepper: A Comedian's Take on How to Save DemocracyARRIVAL (The Film)Don Américo Yábar: Salka Star | Spiritual Journeys with Don Americo  Mihui...the art of 'eating' heavy energyNonverbal Communication Expert For Education + Business Who is Thomas Hanna in the world of Somatics?The Body of Life: Creating New Pathways for Sensory Awareness and Fluid Movementamazon.comGeorge Lakoff - Conceptual Metaphor Theory Arny Mindell: Process Oriented PsychologyHuman Planet: Stealing Meat from LionsBarry Oshry WebsiteLeading Systems: Lessons from the Power Lab by Barry OshryDEI Work: DEI (Diversity, Equity, and Inclusion) Work refers to initiatives and practices ...

In this episode, Bob'nJoyce share a list of OD values created by a team Joyce worked with several years ago. The list resonated with them but what matters more is if they ring true to you. These values are not exclusive to OD practitioners and apply to all of us who lead and we all lead at something. You probably won't find these values on the ODN website or in an academic leadership article. This list is borne out of hard work, determination, and yes, screwing up. Our hope is after listening, you take a moment to reflect on the values important to doing your best work. Here are a few of ours: Embrace humor. Don't take yourself too seriously and know when you are up on your high horse. Reside on the boundary. Know when you are kissing ass and betraying your work. Shrug when you screw up. Come on in. Grab a snack. Welcome!

→ Los Bitchos, Angelica Garcia, Enzo Petillault (programmateur), Smalla x ODN, Johnny Mafia, Association Aides

Le dimanche 10 mars, le palais de Kensington publie une photo de Kate Middleton entourée par ses trois enfants sur les réseaux sociaux. Dans les heures qui suivent, de nombreux internautes détectent des anomalies et se demandent si la photo est authentique. Dans la foulée, plusieurs agences de presse décident de ne pas diffuser la photo.Celle qui est surnommée « Perfect Kate » n'est pas habituée aux faux pas. Depuis son mariage avec le prince William en 2011, elle est appréciée par les Britanniques et participe régulièrement aux évènements officiels. Mais Kate Middleton n'a pas été vue en public depuis Noël dernier, suite à une opération chirurgicale. Cette publication, censée rassurer sur son état de santé, n'a fait que relancer les rumeurs.Pour Code source, Delphine Kargayan, correspondante du Parisien à Londres, retrace le parcours de Kate Middleton.Écoutez Code source sur toutes les plates-formes audio : Apple Podcast (iPhone, iPad), Google Podcast (Android), Amazon Music, Podcast Addict ou Castbox, Deezer, Spotify.Crédits. Direction de la rédaction : Pierre Chausse - Rédacteur en chef : Jules Lavie - Reporter : Ambre Rosala - Production : Raphaël Pueyo, Clara Garnier-Amouroux et Thibault Lambert - Réalisation et mixage : Julien Montcouquiol - Musiques : François Clos, Audio Network - Archives : Le Figaro, ODN, The Royal Family Channel. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.

Tim och Danny har kört Vasaloppet och vi får höra allt om dagen. Vem av dem sket på sig? Vem fick den konstigaste skadan? Vem kom först i mål? Och inte minst, vilka känslor flög genom huvudet när de insåg att de var på väg att gå i mål efter en dvärg? Med på resan var ODN som också gästar avsnittet och ger oss ett värdefullt utifrånperspektiv på hela spektaklet! Handla Sveriges fetaste poddmerch HÄR Bli Patreon till Sveriges härligaste podcast HÄR

Björn har varit i USA med sin, om möjligt, ÄNNU mer teknikanalfabet till bror och sett vad legalisering av marijuana gör med en hel stad. Tim, Danny och ODN har åkt Finlandsfärja och försökt förboka mat... Stötta podden, få 1 extra avsnitt per månad samt rabatt på ny merch och tidig tillgång till livepoddsbiljetter: https://www.patreon.com/manigrupp MIG10 - 10% rabatt: https://algotradingbots.com/ Merch: https://www.slask.gg/mig

Episode 4: Engineering Series What is an ODN access point? How Does O'Brien transition from TNG to DS9? Does O'Brien have rizz? How does O'Brien rely on his crew of Bajoran and Starfleet engineers? Is O'Brien anti-buffer time? Join sisters, Ashlyn and Rhianna as we discuss Miles O'Brien in Deep Space Nine. SPOILER ALERT: Deep Space Nine This is the fourth episode of our Engineering Series, where Ashlyn and Rhianna talk about all the engineers in every Star Trek show, from The Original Series to Strange New Worlds. Hop aboard the Val Jean and hang out with us as we discuss all the best B'elanna Torres engineering moments in Voyager. DISCLAIMER: We do not own any of the rights to Star Trek or its affiliations. This content is for review only. Our intro and outro is written by Jerry Goldsmith.

Małe decyzje zmieniają świat. Gospodarka w obiegu zamkniętym to inaczej – dzielnie się, pożyczanie, ponowne użycie, odnawianie i recykling, a wszystko po to, by zmniejszyć tempo konsumpcjonizmu i wydłużyć życie produktów. „Odnów zamiast wyrzucać” tak brzmi hasło promowane przez Martynę Zastawną, propagatorkę obiegu zamkniętego w rzemiośle, pionierkę cyrkularności w Europie, jedną z najbardziej wpływowych kobiet według magazynu Forbes. Podczas webinaru porozmawiamy o m.in. wartościach istotnych dla współczesnego rzemiosła. O tym, co czyszczenie butów ma wspólnego z ochroną środowiska? Jak układać model biznesowy oparty na sentymentach, gdzie szukać inspiracji i jak budować zgrany zespół? Rozmowę poprowadzi Agata Bisping. W cyklu rozmów „Mistrzowie” Strefy Designu Uniwersytetu SWPS wraz z praktykami ze świata designu rozmawiamy o tym, jak wygląda ich codzienna praca związana z różnymi aspektami kreatywnego projektowania. Strefa Designu Uniwersytetu SWPS to projekt popularyzujący wiedzę z zakresu projektowania: produktów, architektury, wnętrz, mody i komunikacji. Pokazuje, czym jest dobre projektowanie i w jaki sposób realizuje ono konkretne potrzeby użytkowników. Więcej informacji o projekcie: https://web.swps.pl/strefa-designu

Vous écoutez Dig Dig Diggers l'émission des radios Ferarock au Festival Aucard de Tours 2023 ! Découvrez un plateau animé par Radio Béton, Beaub FM, Fréquence Mutine, Radio Primitive de 16h à 18h du 6 au 10 juin 2023. Vendredi 16h > 18h → UTO, Smalla x ODN, Ghoster, Tomane Santarelli

A co je to Design Thinking? Jedná se o přístup zaměřený na inovaci produktů, služeb a procesů. Metoda, která myslí na člověka a jeho problémy. Ing. Štěpánka Uličná, Ph.D. je konzultant, lektor a projektový manažer. Odnáší si praxi z firem jako je například Škoda Auto a GE Money Bank.

#76 Hey everybody, put your digital media away. In this episode, the boyz are talking out-of-home advertising with Ali Broback.  Who's Ali? Glad you asked.  Ali is the chief Client Officer at ODN (Outdoor Nation). Outdoor advertising is such an interesting channel, and in our conversation, we go deep in the paint on the channel:  Here's what you want to listen for:    → What does outdoor advertising look like in 2023 → What separates ODN from other outdoor vendors → How outdoor works in 2023 – it's not just top of the funnel anymore → How outdoor can work with other channels to get results → How to micro-target using outdoor → The biggest mistake clients make with outdoor (You're going to love the avocado story)   And this is just the start. Hurry and get this episode into your earholes!    Connect with Ali on LinkedIn: https://www.linkedin.com/in/alibroback/   If you like this you might want to check out Episode 10 with Scott Goodstein. Scott talks about using outdoor to effectively target audiences.    Want more Kurt or Pat? Yeah, you do!   ✅ Kurt at: https://www.linkedin.com/in/kurtlingel/   ✅ Pat at: https://www.linkedin.com/in/pmcgovern1/  

We chat with Narinder Mahajan CEO of ODN Digital Services (short for ‘Open Doors Now'), a market leader in ‘Shop Now' strategies, enabling brands and e-commerce platforms to sell successfully online. Narinder is a consumer-retail and e-commerce specialist, and has over 20 years of industry experience. During his corporate journey, he worked with various game-changing organizations across diverse industries and formats of consumer retail. In 2015, he turned entrepreneur and co-founded ODN. At ODN he assists 200+ consumer brands across 20+ product categories meet their ecommerce and digital conversion goals. In this chat we touch upon: Understanding ODN's business model and monetisation  Differentiation/USP - explain the "Shop Now" strategy Thoughts on evolution of D2C - threat of rising CACs, shift towards offline, risk off perception of investors etc. Trends to watch in ecommerce e.g. the role of AR, metaverse etc. Hope you enjoy this TRANSFIN. Podcast with Nikhil Arora and Sharath Toopran, where we converse with entrepreneurs and business operators running successful startups, profitable SMEs and family promoted firms on one end, and top investment professionals representing VC/PE/credit funds on the other. The objective is to bring out an "actionable" perspective converging the world of business and investing. If you're a founder and if you'd like us to drill down your model, feel free to drop us a line at edit@transfin.in

Šéf hnutí ANO zahájil finální část kampaně. Jak reaguje na všudypřítomné kritiky a čím dokáže zaujmout své nejvěrnější voličské jádro –  důchodkyně? Vlevo dole bylo u toho.Do prvního kola prezidentské volby zbývá přesně měsíc a Andrej Babiš rozjel závěrečnou část své kampaně. K debatám s lidmi v kulturácích a korzování v ulicích přidal talkshow pod názvem Řeknu vám úplně všechno. Uvádí ji poslanec ANO Aleš Juchelka, jinak je scéna klasická: moderátor za masivním dřevěným stolem, kandidát Babiš sedí jako host na červené pohovce – a samozřejmě nechybí hudební vystoupení.Minulý týden, když šéf ANO dělal kampaně v Karlovarském kraji s divadelním finále v Sokolově, byli u toho Václav Dolejší a Lucie Stuchlíková, kteří natáčeli speciální epizodu svého podcastu Vlevo dole. V expremiérově talkshow se o politice moc nemluví. Zato se promítají třeba fotky z jeho dětství, šéf ANO vzpomíná na studia nebo vypráví, kam rád jezdí na dovolenou, jaké má rád filmy, barvu nebo jídlo. Cíl udělat z Babiše sympaťáka se daří.V hledišti mezi jeho příznivci převažují důchodci a ti odcházejí ze zábavného představení velmi spokojeni. Odnášejí si knihy a autogram nebo selfie v mobilu a šťastní se svěřují, jak se utvrdili ve svém názoru, že bývalý premiér je milý chlapík, který jako jeden z mála politiků myslí na obyčejné lidi.Nechybí ale ani tradiční střety Babišových příznivců a odpůrců – v Chebu se před místním divadlem protestující herci dočkali od fanoušků premiéra ostřejších slov. „Kdybych měla pistoli, odstřelím je všechny,“ je slyšet premiérovu zastánkyni.Babiš na každé zastávce chce lidi přesvědčit, že se změnil, ubral na agresivitě, a v prezidentské kampani se snaží vystupovat jako hodný člověk. Reportéři Seznam Zpráv se ho nakonec zeptali, jestli člověk v 68 letech skutečně může změnit svou povahu, i když má takovou disciplínu jako Babiš.Poslechněte si celou speciální epizodu Vlevo dole - a nevynechejte ani epizody z kampaně Danuše Nerudové a Petra Pavla!-------- Vlevo dole řeší politické kauzy, boje o vliv i šeptandu z kuloárů Sněmovny. Vychází každou středu v poledne. Podcast pro vás připravují Lucie Stuchlíková (@StuchlikovLucie) a Václav Dolejší (@VacDol), reportéři Seznam Zpráv. Další podcasty, ale taky články, komentáře a videa najdete na zpravodajském serveru Seznam Zprávy. Poslouchejte nás na webu Seznam Zpráv, na Podcasty.cz nebo ve své oblíbené podcastové aplikaci.  Své názory, návrhy, otázky, stížnosti nebo pochvaly nám můžete posílat na adresu audio@sz.cz.   Sledujte @SeznamZpravy na sociálních sítích: Twitter // Facebook // Instagram. Seznam Zprávy jsou zdrojem původních informací, nezávislé investigace, originální publicistiky.

Mark Samuel is a writer, speaker, and CEO of IMPAQ, an award-winning international consulting firm. He has developed a unique system for businesses that links Execution, Culture and Deliverables together. The goal of this system is to create cross-functional accountability to successfully implement global changes that increase profitability, build trust and increase efficiency. As an award-winning speaker, Mark has addressed national conferences of ASTD, AQP, ODN, ASHHRA and ISPI. He has impacted audiences all over the world through his thought-provoking and humorous presentations.Key Takeaways Learn about how Mark built up his confidence and speaking skills.It is important to talk from experience. This, in large part, has helped Mark become a stronger speaker. Mark's practices what he has coined "authentic vulnerability." This is being able to be open with your audience and share your weaknesses and imperfections.Shifting from speaking unpaid to creating a business has a lot to do with an inner transformation. It's when you start honoring your voice and your value. Mark believes our ultimate accountability is to ourselves and we should ask ourselves "how do I become the best being I can be?"Your audience is your coach. They can give you feedback on your speeches and help you improve.Memorable Quotes"We don't have to be perfect to be excellent; in fact, we don't even want to be." - Mark Samuel "In order to be paid to do what you love, there are some mindset shifts necessary." - Charles Clark"[Great speakers] say something of value that opens me up to a new way of thinking." - Mark Samuel"[Speakers] are artists. What you write, what you say, it's your canvas. It's your masterpiece. It doesn't have boundaries. You paint the way you want to paint. You say what needs to be said." - Charles ClarkEpisode Resources & LinksMark SamuelWebsite: https://bstate.comLinkedIn: https://www.linkedin.com/in/markssamuel/Instagram: @markssamuel_Twitter: MarkSSamuelCharles ClarkWebsite: https://thecharlesclark.comLinkedIn: https://www.linkedin.com/in/charlesclarkusa/Instagram + Facebook: @thecharlesclarkTo get access to all our episodes, visit our podcast page!Enroll in our Journey to Paid Speaking Gigs program to find your voice and learn how to create your own speaking business.

Spraw, Panie, byśmy wrócili do ciebie, a wrócimy! Odnów nasze dni jak niegdyś! Tr 5,21 Gdy się objawiła dobroć i miłość do ludzi Zbawiciela naszego, Boga, zbawił nas nie dla uczynków sprawiedliwości, które spełniliśmy, lecz dla miłosierdzia swego przez kąpiel odrodzenia oraz odnowienie przez Ducha Świętego. Tt 3,4-5

Tiež ste si všimli, ako sa roztrhlo vrece s prenosnými konzolami? V 79. časti podcastu SHARE_talks smútime za Nintendom, no vítame nový iPhone a zamýšľame sa nad koncom iPod Touch a rozmachom prenosných konzol, ktorých najnovším prírastkom je Logitech G Cloud. Lukáš sa opustil pri nových pravidlách na Twitchi a na konci rozmýšľame nad zmyslom nových verzií existujúcich herných konzol. V novej časti podcastu SHARE_talks hovoríme aj o týchto témach: Nečakaná výhoda plastovej SIM karty oproti eSIM. Od kedy iPhony prestali chudnúť. iPod Touch ako ultimátna prenosná konzola. Prenosné konzoly a cloudové hranie. Hazard na Twitchi a zmena pravidiel. Odnímateľná mechanika na PlayStation 5. Aký zmysel majú medzigeneračné herné konzoly. Odkazy na témy, ktorým sa venujeme: Konkurencia Steam Decku? Logitech oznámil vlastnú handheld konzolu Sony sa údajne pohráva s myšlienkou odnímateľnej diskovej mechaniky v PlayStation 5 Twitch sa chystá zakázať hazard. Najväčším streamerom zároveň zníži podiel z predplatného NAPÍŠTE NÁM: Ak nám chcete niečo odkázať, doplniť nás alebo sme povedali niečo zle a chcete nás opraviť, môžete nám napísať na podcasty@zive.sk. Všetky e-maily čítame a na väčšinu sa snažíme odpovedať. Podcast SHARE_talks spoločne pripravujú magazíny Živé.sk a HernáZóna.sk.

In this episode of the Group Dynamics podcast, I am talking to David W. Jamieson, president of NTL Institute for Applied Behavioral Sciences about the Use of Self – a highly relevant topic, especially for leaders and change agents. While discussing, we are talking about choices we often don’t see, because of the daily pressures of our work. We also talk about the possibility – or even necessity – to show up as a fully integrated person. To be able to become that we have to embrace our shadow side which will become apparent, while we discuss an incident at work where position power and force was used by me (Juergen, the host), not seeing other choices. So this is a very personal episode. Books, articles and videos we briefly mention or recommend: Palmer, P. J. (2009). A hidden wholeness: The journey toward an undivided life. john Wiley & sons. Palmer: What is a divided life?: https://youtu.be/gCvIZpMo8aY Use of Self as an OD practitioner: https://maraineyassociates.com/wp-content/uploads/2015/12/UseofSelf-Practitioner.pdf (2022-04-21) About David Dr. Jamieson is President of NTL Institute for Applied Behavioral Sciences (https://www.ntl.org). He is also President of the Jamieson Consulting Group, Inc. (providing consultation, leader coaching & speaking) and a retired Professor, Organization Development & Change from the University of St. Thomas. He serves as Distinguished Visiting Scholar in 3 other graduate OD programs. His work has involved consulting with over 100 organizations (private, non-profit, government, community), coaching dozens of leaders, teaching next generations of leaders and change agents, and providing thought-leadership through publishing and speaking. He received his Ph.D. in Management from UCLA, majoring in Organization Design & Development and a BS in Business Administration from Drexel University, with a Behavioral Science minor. He is a Past National President of the American Society for Training and Development (now ATD) and Past Chair of the Management Consultation Division and Practice Theme Committee of the Academy of Management (AOM). He has been honored with The Lifetime Achievement Award from the Organization Development Network (ODN), Distinguished Scholar-Practitioner Career Achievement Award from AOM, Distinguished OD Educator from the OD & Change Division of the AOM, Sharing OD Knowledge Award from the ODN, a past-Chair of the Organization Development Education Association. Dave is author or co-author of 8 books, 17 chapters, and dozens of articles in journals and newsletters.His current writing includes a practitioner book on Use of Self and a new book on Strategic Organization Design. He serves as, Editor, OD Review, Assoc. Editor, Journal of Management Inquiry, and Review Board Member, Journal of Applied Behavioral Science. He balances his time among partnering on change projects, formal and informal educational endeavors, presenting or writing his thinking for professional audiences, and coaching all who need to lead change.

Tretia časť k môjmu životu s ODN sa týka posledného dielu tejto skratky. Dnes budem rozoberať tretie slovo: nepochybuj. A keď si tento tretí diel vypočuje, tak ti to všetko krásne zapadne do seba a ak začneš ziť podľa ODN, tak tvoj život sa stane o poznanie ľahší. Za to ručím :) Takže určite počúvaj do konca.

V predošlej epizóde sme zvládli O zo skratky ODN, ktorá symbolizuje môj pohľad na život a ako žijem svoj život ja. ODN znamená Odovzdaj sa, dôveruj a nepochybuj. Dnes sa povenujeme druhému písmenu D - dôveruj.

In today's episode, Bob'NJoyce explore ODN's 5th and final OD core competency, Informed Consultant. This competency draws on an OD practitioner's organizational awareness, commitment to diversity and inclusion, and possessing a toolbox of OD interventions that drives a company's success. We use the term OD Sherpa, a person with the endurance to overcome difficult circumstances and the skills to lead the way, to best describe this OD competency.

V tejto epizóde je mojím zámerom požiadať ťa, aby si sa pozrel na seba a pozrel sa na svoj život, ako si uväznený v snahe všetko kontrolovať a možno o tom ani nevieš. Keď budeš žiť z paradigmy, ktorú navrhujem v tejto epizóde, ODN, tak tovj život sa stane oveľa ľahším a slobodnejším. Čo znamená ODN? Jednoduché: Odovzdaj sa, dôveruj a nepochybuj... A to je téma tohto týždňa.

In this episode, Bob'nJoyce explore ODN's 4th OD Competency – Credible Strategist. This competency requires OD to have a leadership presence and the emotional intelligence to influence strategy. Bob'nJoyce share examples of their work on shaping successful strategies in partnership with top leaders. This episode explores what it means to be credible and how you get there. This competency requires OD to be in touch with what is happening at every level of an organization from the break room to the board room. This is a tall order but so worth the effort. Come in. Grab a Valentine treat. Welcome!

In this Episode, Bob'nJoyce explore ODN's 3rd OD Competency – Business Advisor. In today's chaotic, unpredictable world, leadership needs trusted OD business advisors to get beyond current thinking and explore new possibilities to tackle modern challenges and opportunities. OD practitioners, with their system thinking and curiosity are in a unique position to add value as a business advisor. So come on in. Grab a snack. Welcome!

Today we explore ODN's second OD competency, efficient designer. We speak to this competency's importance and what its impact is when done well. We give examples of how OD design processes positively impact an organization's success. We ended up agreeing that the role of efficient designer brings the necessary structure and organization to deliver robust results.

Today, we continue to explore “OD's job description” as defined by ODN, a network of OD scholars and practitioners committed to creating effective, healthy organizations. In this episode, we focus on the first, and arguably most important competency - System Design Expert. This competency blends the ability to assess what is happening in an organization (that contributes to or impedes progress) with the development of effective change strategies. Being a system change expert is about doing high impact work that improves organizational effectiveness. Today Bob ‘n Joyce share their success and hacks when doing this work and the lessons they have learned. No organization has escaped the need to pivot and change quickly in these volatile times. System change experts create the conditions that make this happen. Come in. Grab a snack. Welcome.

#kazanie #homilia #Szklanka_Dobrej_Rozmowy Czytania liturgiczne Kolor szat: fioletowy 1. czytanie (Mi 5, 1-4a) Mesjasz będzie pochodził z Betlejem Psalm (Ps 80 (79), 2ac i 3b. 15-16. 18-19 (R.: por. 4)) Odnów nas, Boże, i daj nam zbawienie 2. czytanie (Hbr 10, 5-10) Chrystus przychodzi spełnić wolę Ojca Aklamacja (Łk 1, 38) Alleluja, alleluja, alleluja Ewangelia (Łk 1, 39-45) Maryja jest Matką oczekiwanego Mesjasza 19 grudnia 2021 Niedziela, IV Tydzień Adwentu Rok C, II Czwarta Niedziela Adwentu więcej na www.studenski.pl

Do Čedoku nastoupil v roce 1992 jako průvodce a za studií tak kombinoval příjemné s užitečným – tedy cestovatelskou vášeň s přivýdělkem. Po téměř třech dekádách v cestovním ruchu se Stanislav Zeman do nejstarší české cestovky před třemi lety vrátil, tentokrát jako její CEO. To samozřejmě netušil, že bude muset firmu s třímiliardovým obratem provést největší krizí, jaké za sto let existence čelila. Po prvním koronavirovém roce vypadaly výhledy do budoucna dost temně: podle Světové organizace cestovního ruchu se počet turistů snížil o 74 procent a na letošek organizace vyčíslila ztráty globálního turistického průmyslu na 1,3 bilionu dolarů (bezmála 28 bilionů korun). Bilance po letní sezoně je však mnohem optimističtější. Čedok, v zádech se silným akcionářem v podobě polské cestovní kanceláře Itaka, hlásí úspěšné léto s nárůsty prodejů nad úroveň roku 2019. Před zimou tak Stanislav Zeman hýří optimismem i novými nápady. Jak Čedok zvládá pandemickou krizi? Odnáší si z ní i pozitivní zkušenosti? A jak se podle Zemana změní pravidla byznysu, který za uplynulé dva roky utrpěl astronomické ztráty?

In Conversation with Narinder Mahajan Co-Founder of ODN Digital, De Zero Stories Podcasts attempted to walk along the street of Content Marketing, Brand Story Telling and Craft of ODN Digital that made them India's Leading Content Marketing Agency. About ODN Digital: Started in late 2015, ODN rides on a journey of digital transformation for brands with extensive experience of top management in online marketing, sales, and retail. ODN builds innovative and unique content solutions for e-commerce marketplaces and global brands. The company designs and delivers high-quality content and leads in new-age ways of manifesting creative ideas. Stats on the Company: Incepted in 2015, ODN Digital was started by Narinder Mahajan who witnessed big investments going into various marketplaces, social media, and digital marketing for e-commerce that led him to think about who could provide amazing content at a dynamic speed for these rapidly growing platforms. The company is currently serving about 200+ global clients spread across verticals The company is also one of the very few approved studios in the country for Flipkart.com and Myntra.com (biggest names in fashion e-com in India) The key clients of the company include names like M&S, Nykaa, Paytm, TataCliq, Whirlpool, Diesel, and many more. Today, ODN is a proud partner with Fossil to provide them with global shoots and cataloging services for their entire APAC region across 40 marketplaces and 13 countries www.odndigital.com

OD practitioners wear a lot of hats. In this episode, Bob'nJoyce sort through these many hats using the Global OD Model developed by ODN. This model defines the discipline of organizational development and assesses areas for professional development. We discussed: • The multi-faceted work of an OD professional working inside a company and the richness of the work as well as the complexity of the many hats worn when working inside. • The work we have done that fits under each segment of the Global OD Model to show the benefit of having a model that provides grounding for both the OD leader and the company • The benefit of the model to serve as a kind of “you are here” map that helps both the practitioner and the company to understand the work and give context.

Sofoniáš 3, 14 - 18: Zaplesaj, dcéra Sion, zvučne pokrikuj, Izrael, raduj sa a jasaj celým srdcom, dcéra Jeruzalem! Hospodin odňal rozsudky nad tebou, odvrátil tvojich nepriateľov. Hospodin, kráľ Izraela, je uprostred teba, nebudeš sa už báť zlého. V ten deň povedia Jeruzalemu: Neboj sa, Sion, nech neochabnú tvoje ruky! Hospodin, tvoj Boh, je uprostred teba ako zachraňujúci hrdina. On radostne zaplesá nad tebou, obnoví ťa vo svojej láske, bude s plesaním jasať nad tebou ako za dní slávností. Odnímem od teba a odstránim z teba potupu.

The World Famous Insurance Dudes chat with Carey Anne NadeauABOUT CAREY ANNE Founder and CEO, Carey Anne Nadeau is an MIT-trained city planner and has spent years studying cities at the Brookings Institution and Urban Institute before launching ODN in 2014. The company has received acclaimed success as a smart-city consulting firm and has worked with municipal departments of transportation and planning to deliver predictive risk insights to better management public fleets and traffic safety programs, including Vision Zero.Carey Anne went on to found ODN, which brings together geospatial data and rates each road with a prediction of the probability of a crash. By pairing these insights with location-based driving data, ODN helps the auto insurance industry promote safe driving. Carey Anne also hosts the GolfCour.se podcast, a modern, inclusive forum for business conversations in insurance.For her thought-leadership, Carey Anne was invited to be a board member of Women Leaders in Insurance and Washington Life Magazine’s Top 25 Women in Tech.Apple | Google | Spotify | Stitcher | iHeart | Listen NotesWanna get on the mailing list for SNEAK peaks and insider info head over to http://www.theidudes.com Interested in Dudes4u services and / or becoming a member of the Insurance Dudes Elite Members Only Group? Need Telemarketing Or Leads? The iDudes have you covered. We will get your experienced callers, train them, and have them transferring you leads in no time! Want Exclusive Leads straight to your CRM and Email inbox for under $10 each? Head to www.dudes4u.com to get more info and get started before all the spots in your state are gone! (Limit per state)Support the show (https://www.dudes4u.com)

There is no predicting of what may happen on the road. The best thing we can do is take precautionary measures. Taking that to heart, Carey Anne Nadeau founded ODN—a company that builds AI products that augments what insurance carriers know about who their customers are with information about where they drive and their risk exposures on the road. In this episode, Carey explains further to us how they do this and the risk rating methods they use to measure environmental hazards on the road. She also taps into the use of big data, shedding light on how far we've come in terms of the technologies we have to predict and protect ourselves. With technologies like this, the future is bright for the taking. All we need is to take advantage of services like that from Carey's ODN.

Carey Anne Nadeau, Founder and CEO of ODN joins us today. ODN predicts where car crashes are likely and gives carriers the ability to better price personal and commercial lines insurance.  Our conversation ranges across a number of actually related topics: Urban planning, red-lining, the social impact of machine learning, and ways to increase the adoption of new technologies by insurance carriers.       Connect with Carey Anne Nadeau: Website: https://www.careyannenadeau.com/ LinkedIn: https://www.linkedin.com/in/careyannenadeau Twitter: https://twitter.com/canadeau?lang=en   Connect with Nassau Re/Imagine:  Join Our Incubator Program  Website: Imagine.nsre.com     Connect with Nassau Re:  LinkedIn: Nassau Re  Website: NSRE.com   

Data is power. It creates. It moves. With data comes knowledge and information that can be integral and crucial to a business, organization, even an infrastructure of a city.   This week, we talk with a business that makes sense of data points and turns it into useable, logical big data.   On this week’s episode of FNO: InsureTech, we are joined by Carey Ann Nadeau, Founder & CEO of Open Data Nation (ODN). ODN combines detailed public records and industry expertise to reveal new, leading indicators of risks in cities. By measuring the risk around customers, they are able to develop customized profiles of data points that are unique and applicable.

Welcome to The Golf Course, a modern forum for business conversations in insurance. Today, I’ve invited Jason LaMonica of AXA XL to join me for a round on the podcast. We chat about what it’s like to launch a new line of business and the importance of providing value-added risk management services and support to customers. For more information on Jason or subcontractor default insurance (SDI) visit: https://axaxl.com/insurance/about-us/our-experts/jason-lamonicaLet’s tee it off.

Very happy to have World Team coach Kelly Springer on the show! We talk a lot about ODN as well as fielding a team and the build-up to World Championships. Thanks so much Jimmy Blair and Pinnacle Racing for all you do for Skate Talk with Boomer and the Coach. You'll definitely see Jimmy and Pinnacle at all the big events coming up. Skate your best with Pinnacle Racing!

In today´s episode of Agents Influence, host Jason Cass interviews Carey Anne Nadeau, Founder and CEO of ODN, Insurtech Founder and Data Expert. ODN predicts where car crashes are most likely to happen to increase the profitability of traditional auto insurance underwriting and telematics programs. Carey Ann Nadeau shares how she arrived in the big data industry and what her company ODN is able to accomplish and improve in the insurance field.

Carey Anne Nadeau is the CEO & Founder of ODN, a data science and insurtech company that collates and interprets public records and statistical data to give clients quantifiable advice on business risks. Carey combines the spirit of a success-driven entrepreneur and the intelligence of an MIT-trained statistician to modernize the way we do risk management. She has a Masters degree in City Planning from the Massachusetts Institute of Technology and a Bachelor of Arts in Public Policy from the George Washington University.  In this episode, Carey describes how her company aims to revolutionize the way we measure risk. She shares the challenges she faced in corporate America and the reason she founded ODN. She shares some mind-blowing statistical facts and explains how they gather data and measure it. Carey also explains why those new to the industry should invest more in social media. “In the United States, there’s enough data now to build predictive models and use that data to reliably estimate where things are going to go wrong.” - Carey Anne Nadeau Today on Spot On Insurance: Carey Anne Nadeau's humble beginnings and how she came to join the data science industry. Why she chose to get a degree in City Planning. Her childhood and how her past experiences guided her to where she is today. Her struggles against the corporate patriarchy and how she overcame them. The political thoughts that helped her focus on data science. What ODN stands for and how she came up with that name. The kind of public records available and what their company seeks to do. The big problem with insurance pricing models. Exciting facts regarding public records and data trends. Key Takeaways: If you're promoted to a higher position with more duties, make sure to check that against the people doing half the job as you are and getting paid twice as much. About 2.5 billion records are produced every year by the US government. Data science can make an otherwise dull number into a mind-blowing statistic. Resources Mentioned: Ep.104: The Student Debt Crisis and How Employee Benefits Can Help Insurance Nerds Connect with Carey Ann Nadeau: ODNsure LinkedIn This episode was brought to you by….. Insurance Licensing Services of America (ILSA), America’s Premier Insurance Compliance and Licensing experts. To learn more about ILSA and their services, visit ILSAinc.com. Connect, Learn, Share Thank you for joining us on this week’s episode of Spot On Insurance. For more resources and episodes, visit SpotOnInsurance.com. Subscribe so you never miss an episode. Love what you’re learning, Spot Light your review on iTunes and share your favorite episodes with friends and colleagues!

It will have a lot less to do with who is driving and a lot more to do with where and when you're going someplace. No two roads are created equal and neither are the unique driving conditions that change by the minute. It's been such an unknown variable it's never been considered a possibility to impact the auto insurance bottom line. However, data has no limits and today we're on the verge of this new information adding a lot to the conversation. That's what I talk to Carey Anne Nadeau, Founder, and CEO of ODN, about knowing the true cost of real-time road conditions.

It will have a lot less to do with who is driving and a lot more to do with where and when you're going someplace. No two roads are created equal and neither are the unique driving conditions that change by the minute. It's been such an unknown variable it's never been considered a possibility to impact the auto insurance bottom line. However, data has no limits and today we're on the verge of this new information adding a lot to the conversation. That's what I talk to Carey Anne Nadeau, Founder, and CEO of ODN, about knowing the true cost of real-time road conditions.

Carey Anne Nadeau, Founder of ODN, interviews Marvol Barnard, incoming President of the LPGA Teaching and Club Professionals. Marvol shares her thoughts about the importance of social networking in insurance and her strategies to promote diversity and inclusion, all while having a fun time.If you're looking to learn more about the LPGA and becoming a certified teaching professional, visit: http://www.lpga.com/tcp #inviteher

In this episode of Profiles in Risk, you can meet Carey Anne Nadeau, who will be a guest host of Profiles in Risk indefinitely. We talked about the overwhelming amount of municipal data being captured, ODN's mission for that data and how the insurance ecosystem can use that data and insight. Big Data has come to insurance, the data has arrived!CONNECT WITH CAREY ANNE NADEAU: LinkedIn - https://www.linkedin.com/in/carey-anne-nadeau-9a15a37/ ODN - https://www.odnsure.com/ MENTIONED:Rush (Greatest band of all time?) - https://amzn.to/2ToM7MU BOOKS RECOMMENDED BY CAREY ANNE: The Economy of Cities by Jane Jacobs - https://amzn.to/2DKNrov SUBSCRIBE AT:Buzzsprout RSS: https://goo.gl/5K4X3QGoogle Play: https://goo.gl/WMAvW4iTunes: https://goo.gl/7SqwvP Overcast: https://goo.gl/8b4cbD Spotify: https://goo.gl/niAbGN Stitcher: https://goo.gl/DmE7MiYouTube: https://goo.gl/1Turar

With search engine optimization changing so much, what's the secret to succeeding with SEO in 2018? This week on The Inbound Success Podcast, SimpleTiger CEO Jeremiah Smith shares his insights on what's working - and what's not - with SEO. As the head of an SEO agency, he's worked with quite a few clients to solve SEO challenges and gets into specific detail on things like how to approach site structure, navigation menus, keyword and backlink strategies and more. He also shares his predictions for how voice search will impact the future of SEO.  So much good stuff - check it out! Listen to the podcast to hear Jeremiah's SEO insights and get specific, actionable things you can do now to improve your search rankings. Transcript Kathleen Booth (Host): Welcome back to The Inbound Success podcast. I'm your host, Kathleen Booth, and today my guest is Jeremiah Smith, who's the founder and CEO of Simple Tiger. Welcome, Jeremiah. Jeremiah Smith (Guest): Thank you so much for having me, Kathleen. I'm happy to be here today. Jeremiah and Kathleen recording this episode Kathleen: Awesome. Tell the audience a little bit more about yourself, and about Simple Tiger, and what you guys do over there. Jeremiah: All right. So I am the founder and CEO of Simple Tiger. We're a digital marketing agency that specializes in doing search engine optimization for softwares and service companies. We do a lot of the inbound marketing follow elements, but we really try to tailor everything tightly around how it impacts SEO, since that's been our specialty for over 12 years now. Kathleen: Great. And I had a lot of fun combing through your website, and particularly through your profile page on the website. The one thing that stood out the most was in your bios. You guys have these really cool answers to questions and one of them was shark diving, bungee jumping, or ... I think the other one was cliff diving. And you picked shark diving, which is probably the one that would be the last on my list. So- Jeremiah: That's funny. Yeah, I was thinking through those and I actually ... I always like to challenge myself but I'm pretty calculated with how much risk I can handle. So when it comes to bungee jumping, to me that's like right out, that's so dangerous and crazy, and it's not even enjoyable an idea to me, whipping my neck around and everything. Cliff diving is something I've actually done a lot of. And that's fun and easy to me. It's not as scary. Shark diving is that one that's right in the midst, the Goldilocks zone for me. That's dangerous, but it's somewhat safe. And so, yeah, that's pretty much where I land on that. Kathleen: So it's really funny. The reason that stood out to me was that I'm kind of familiar. I read what you wrote about trying to face my fears. And I have not done cliff diving yet, but I have done bungee jumping off of the bridge over the River Zambezi in Africa, which is ... At the time it was the second highest bungee jump in the world. Kathleen bungee jumping in Zambia And I did it back when I was 30-years-old. And it's so funny, because in the last few months ... I have this picture of myself launching off the bridge, that somebody else took. And the last time I looked at that picture, I was like, "Damn, it's a good thing I did that back when I was 30, because I would never do it now." Jeremiah: That's amazing. Kathleen: But I would never swim with sharks. I would never swim with sharks, though. So for me, the bungee jumping was the thing that was right on the edge, and the shark stuff is like, yeah, no way.  Jeremiah: That's so funny. It's funny how we're different like that. I'm sure someone out there is like, "Cliff diving? That's the one that's right on the edge for me." Kathleen: Totally. Totally. So I had a good chuckle reading that part of your website. Jeremiah: That's awesome. Kathleen: Yeah, so I was interested to talk with you because you all, as you said, you specialize in search engine optimization, and you work with a lot of SaaS or software service companies. And that's a super competitive field. And these are, in my experience, at least, having been in digital marketing agencies for a lot of years, I won't say how many ... SaaS companies tend to spend money on this kind of stuff. And so it's not like being a garbage hauler and the competition for your keywords isn't as strong. These are companies that are putting some dollars behind not only their pay-per-click marketing, but they're spending money to do SEO right. So I'm fascinated to learn a little bit more from you on both what you see as working well right now, and how you're helping to prepare your clients for the future, given all the changes that are happening in SEO these days. What's Working With Search Engine Optimization in 2018 Jeremiah: Yeah. Yeah, that's a great question. And I got to be honest, though. You're going to have to stop me at some point because there's so many answers I want to dive into on that. Kathleen: Go. Jeremiah: Let's see. So having been in this for 12 years now, there are so many different things that we've done that, at the time, were valuable things. And SEO is interesting because it's one of those things ... It's one of those marketing methodologies where there are trends within that space. So there are trends in the SEO that right now, for example, might be very powerful for SEO but a year or two ago weren't, and a year from now, won't be. So you've got to keep that in mind and adapt to those as they come and go. But there are some strong core elements that are always ... They're always strong. They may not be the leaders in the space, but they're strong. And if you do those well, you'll always be successful at SEO. And so a couple of things that we're doing nowadays that are just a little bit different than before ... One of the hot topics for 2018 has been content structure and structuring content on your site and navigational structure, which making sure that your navigation's set up in a way where you're actually able to dive in to the depths of the content on the site through the navigation. That's evolved quite a bit. Google's gone from hating large menus to loving large menus to hating them again to loving them again. And it's a little bit nauseating trying to figure that out. But we've determined some patterns and seen some sites that have really good navigational structures, really good content structures. And we've seen the benefits of that. Everything from a large enterprise eCommerce site, all the way to a small SaaS company that has one product, one offering, very simple. Like, for example, Stripe. You think about that. Such a simple offering. There's not much to it. But you can go deep on their content because of the developer applications and things like that. So we're finding the content structure's been a very powerful thing. And I think a large part of that actually has to do with the way Google has devolved in terms of adapting more machine-learning technology to enhance the user experience of Google. So Google's trying to get more intelligent about what they bring up or what they show as results. And as you're doing that, as you're reverse engineering that, you're noticing what they like more. And what they're liking more is just really, really good content structure, which, I guess good is a subjective term. But you almost have to know what I mean when I say that. I could probably explain that a little more, but I'd have to show you examples, really. Kathleen: Yeah, let's go back to the menu for a second because that's something that I think is interesting and easy to overlook, right? A lot of people build their websites and the navigation menu they think, "I need to get it right. But it's not something I need to spend a ton of time on." And I think a lot of folks don't even think of it when it comes to SEO. So can I dig a little bit deeper in there? And you mentioned larger menus. Are you talking about actually displaying a mega menu at the top of a site? Or are you talking about the page hierarchy and having several pages, subpages, etc.? Walk me through what that big menu looks like. Jeremiah: Sure, yeah. So the mega menu discussion is interesting because there are cases ... Theoretically, Google would say that they don't like mega menus. And when we talk about mega menu ... And it makes sense why they wouldn't because, from a user perspective, they're not great either, usually. What a mega menu means, when we talk about that, is usually a menu that contains upwards of a hundred navigational links or more, just massive. And you could just spend all day just trying to hover through this menu to get to where you want. That's too much. It's too much for a user perspective. It's too much from a search engine perspective, which mirror each other. And especially with the increase in users on mobile devices, mega menus just aren't making as much sense as they used to. However, in certain applications, on certain websites, for certain types of content, certain content structure, a mega menu is the only way. And it actually works really well. And so it's real interesting to see the cases where the rules can be broken. And that's probably the hardest thing to learn in SEO, is knowing where and when you can break certain rules in order to succeed because you're going to have to at some point. For example, Brian Dean does some really cool posts about breaking some of the most common rules in SEO. For example, he's got over 10,000 YouTube subscribers and he's only got 10 YouTube videos. That's a huge deal. You got a significant amount ... I think he has over 100,000 YouTube subscribers. He's got ... Whatever those huge tiers are, he's got it, right? He's only got 10 YouTube videos. Kathleen: And he just released a course on that, too, I think. I feel like he just released a course on YouTube SEO, to talk about how he did that. Jeremiah: Right, right. And that's a great example, though, of him breaking the common rules, where people think you've got to post a ton videos, you got to be on there every single day to get to 100,000 subscribers. He's only done a few, few pieces of content. They're rockstar pieces of content, and he is internet famous because of it. So when it comes to menus, for example, I think some of the larger sites that have a lot of complexity, over time, I think Google is going to get intelligent enough, and currently is intelligent enough, to deduce the fact that, "Hey, this is a complex subject, what this site is about." And it can be broken off into these relevant subsections or subcategories of deeper subjects. And it makes sense. Wikipedia is a great example of that, for example. You can't for the life of you use the Wikipedia menu to get where you want to go. You have to use search. And their search engine even sucks. So you have to use Google to get through Wikipedia, appropriately. But their content structure and linking to deeper, relevant subjects, cross linking, and all that kind of stuff, is really what makes them successful. So I don't know if that answers your question. But there's not really a one-size- fits-all menu solution. It really depends on the case-by- case basis. Kathleen: Okay, interesting. And then in terms of the other thing you mentioned was structuring your content well. So as you said, that's an easy thing to say but there's a lot of nuance behind that. Can we dig into that one a little bit deeper, and maybe give some examples of different ways that companies need to think about structuring their content? Jeremiah: Right, yeah. And I think the best way to structure content, honestly, I don't think is to look at it from a keyword perspective. We did that for a very long time. And we tried to nest everything under keyword umbrellas. And over time, what we learned is that actually the way the user is interacting with your website might be sequential and break from a keyword norm. So let's think for a second about an example software tool. And I'll walk you through how this might apply, and how we might structure content for this one client, where previously we would nest everything under a keyword umbrella. So let's think about ... I'll always pick on invoicing software, because I think that's an easy concept to understand and it applies to every business I'm talking to, so they get it. It's familiar. In this invoicing software, maybe our target is CFOs at software companies. And that's who we want to sell this invoicing software to. Well, that CFO at the software company has a certain list of pain points and things that they really want to work through and boxes they've got to check for them to procure a solution for their invoicing software. They know what they're looking for. So in the old days, what we would do is take "invoicing software" as a mothership term, and then play with subcategories of keywords related to invoicing software. In the new days, we'll still do that, but we're going to break out of that and we're probably going to structure it a way where it's the number one pain point the CFO might have with software. Let's do that as our first piece of content, even if that keyword is not our top target keyword. Because from an engagement perspective, that might be their top concern. But that keyword may not have as much search volume as some of the other keywords in invoicing software. And for our second piece of content, below that in the menu, is their second largest pain point, which, again, may not be a high volume keyword. By structuring the content like that, we optimize those pieces of content for the keywords that are relevant to them. And we do our best to promote other pieces of content that are relevant to the other keywords that are higher search volume, whether that's large blog articles containing an infographic with all kinds of clickable stuff in the content or not. But what we're trying to do is set up a flow of content on the site that's going to keep that CFO searcher engaged. And if we can keep that searcher engaged, that's going to trigger some new algorithmic metrics in Google that are actually going to help you rank better. So I'm starting to get into some deeper SEO stuff with what Google's doing in artificial intelligence here. But for the longest time, Google has looked at links as the number one ranking factor in search. And everyone always wondered, "How do you build links? How do you build links?" and just trying and competing with each other, and trying to find ways to do it naturally. And it's the hardest thing to do in searching software is link building. Period. No matter what anyone says, link building's the hardest. Well, Google has now, for the first time, overstepped links in their algorithm as the most important factor with another one, which is user engagement metrics. So Google is now using clickstream data through Chrome and through other clickstream data providers. If you have Analytics installed on your site, if you have Google AdWords conversion tracking set up on your site, I don't doubt for a second that they're monitoring traffic usage and how people are interacting with your site. They're not publishing that content or that information or that data anywhere because of encrypted relationships that Google wants to keep tight and internal and private. But they are using that data to determine how your site ought to rank. So if people are actively engaging with pieces of content on your site moreso than other pieces of content on your site, those pieces that they're engaging with have a higher likelihood to rank than the ones they're not engaging with, regardless of links. So that's a really interesting new frontier, if you think about it. Now that doesn't mean that links don't matter. Links are still extremely important. You've got to have those, too. When it comes down to it, if everyone has 10 of the same high quality links, then whichever pages are getting the best user engagement are the ones to get ranked. Kathleen: On the subject of user engagement, it's interesting that you bring this up because I've had a couple of other people get at this topic from different directions. One of the things that has come up is time on page, for example. And I think I had one guest who talked about how they're using more and more video on their pages because it tends to get people to spend a little bit more time. Are you finding that that's the case or are there other page elements that you've seen successfully keep people sticky on pages? Jeremiah: Yeah, I think any kind of mix of media that is set up in a way where it's going to either force or entice or you coerced the user into spending more time on the page is better. So what we're looking for, first and foremost, when we're dealing with your clients, a large portion of it is not that we're dealing with clients who just need to get users to spend more time on the page and don't know where to begin with that. Most of the time something is going wrong with their site that's causing users to leave early, like there are actual problems. And we need to address those first, because those are leaks in the ship. We've got to plug those holes before we do anything about racing the ship. So some of those plugs are like interstitial popups that we see that aren't working well, we'll try to kill those. If they are working well, we'll try to find ways to just make them a little less intrusive, a little bit of an easier interaction, an easy way to close out. For those who don't realize it, you can just click off of it or click the little X or whatever, try to find a way to close out faster. Random popups, random little engagement elements that interrupt the experience, we try to find ways to kill those if we see that they're killing conversions or that they're killing user engagement. Some of those things actually increase user engagement. For example, Drift is a really cool tool that allows for this whole conversational marketing element to take place. That tool alone increases engagement on your site or increases time on page if somebody interacts with it. If somebody clicks on it and they start a conversation, it doesn't matter that they're just ... the page is just sitting there in the background. Whatever page it is, suddenly they're interacting in this little chat box over here and that page has longer user engagement now. Little metrics like that, little things like that can help. I would recommend the use of video so long as it makes sense to the audience. That's something you need to test. When you do load video on your page, something I'd recommend is to use something like Wistia or some kind of video that allows you to have analytics within the video and see how many people are actually interacting with that video element out of the total visitors coming to the page. If it's a very small portion, it may not make sense and it may not help you. You may actually want to A/B test having the video on page versus not. One thing that I've seen work well is the promise of a video but the video's embedded way down the page, so it forces you to scroll. As you scroll, you're scrolling past really interesting images and bolded text and headings and things like that that catch your eye and slow you down, cause you to spend more time on the page before you even get to the video. These are all just interesting techniques that I don't think are manipulative, I think are intelligent. If you do it in a genuine way, I think it works really well. Kathleen: Now are you finding that you're building out or you're working with your clients to build out longer pages because of this? Jeremiah: Depends again. A lot of times, yes. A lot of times, the competition is showing long pages and that's what's ranking. We're in a position where we're either going to have to come up with some stellar short content that is just silver bullet short content or we're just going to have to play the game and write some long content, too. Most of the time we find ourselves in a position where we're trying to write a little bit longer content than whatever is consistently ranking well and just play leap frog. That just tends to be the name of the game. Now of course in that regard, you don't want to go stuffing fluff into content. That's something that we're very careful about and we steer away from. If we find that it's difficult for us to break an 800 word threshold on a subject, then we'll start digging into the search results for that subject and use a little bit of the skyscraper technique, which is where you take a keyword. You grab the top several results and pull from all those pieces as sources and rewrite some of that content into your own and reorganize it. You're adding the average value of the top 10 results in Google into one article. It tends to be a lot more weighty and help you in the rankings. That's what we find ourselves doing in the event that we can't fill up a piece of content as easily without adding fluff. Kathleen: Yeah. Gosh, there's so much here that I want to ask you about. It's interesting. To hit rewind, we have Drift on our site and we implemented it, I want to say, back in March. It's definitely increased engagement quite dramatically to the point where we originally had one person manning the live chat and now we have three. It's been very interesting to watch. I think especially if you have somebody good who understands how to engage in a live chat conversation, it can make a tremendous difference. I remember though we were worried at the time about what Drift was going to do to our page load speed, especially on mobile, because Google is looking so much more closely at mobile page load times. I don't think at IMPACT, we have not become subject yet to mobile first indexing, but that's something that we kind of obsess over. I know Drift loads asynchronously and so in theory at least, it shouldn't affect your page rank on mobile. But it's a cool product and it's hugely ... it's made a tremendous difference in terms of engagement. Jeremiah: Yeah. There is that challenge, too. This is a huge challenge for SEO specifically is the trade-off between user engagement ... well, it's not a trade-off between user engagement. It is a feature that may help user engagement in one way but hurt it in another where, just like what you're saying, where Drift improves user engagement because you're offering a feature that they didn't have before. There's a technical load that comes with it that actually slows down the experience and that actually hurts user engagement. It's trying to decide, well, is this worth it or not? Is this hurting us or not? There are a lot of those kinds of things that we run into where we have to make decisions. We have to tell clients to maybe cut features that are good features but they're hurting them technically. Kathleen: Yeah. Jeremiah: Just wait til a better solution comes around or try to develop one or find one yourself. Those are sometimes better options, but yeah, it's fun to have all these tools to play with, too. I think that that's something us marketers get carried away with is the next flashy thing. I know we do that at SimpleTiger all the time. We're big nerds, so you'll come to our site and we don't follow the rules we're talking about on our own site. We're testing everything. Kathleen: Neither do we. Jeremiah: Oh my gosh. I've got way too much code on the back end tracking everything. I've got Drift and all these things popping up and sliding in. You'd just be like, "Ugh, SimpleTiger's awful." But yeah, we're testing stuff to see what works, see what we like and what helps, what hurts. That way, whenever a client runs into an issue, we've seen it before at least on our own site. The very first client, we can go ahead and fix something for them. Kathleen: Amen. It's so funny because we are the exact same way. We are so "Do as I say, not as I do" because we're constantly testing to see if going the opposite direction of what everybody else is doing might work. We've always said we need to be a laboratory. We need to make the mistakes on ourselves and learn from them so that we are not exposing our clients to more risk than they need to have. It's an interesting dynamic with agencies where very often, they are not necessarily exemplifying best practices. That's because we are testing and trying to be a little bit more leading edge, which is interesting. Jeremiah: Yeah. I agree. My brother and I joked about starting a side business to be our guinea pig for everything so we don't ruin our agency with all the experiments we're running, you know? Kathleen: Yeah. I'm curious, you mentioned moving from Google used to be all about links and keywords. Now you're moving more in the direction of solving for the user. How much of that do you think is connected with this evolution that Google is undergoing right now from an algorithmic-based search result to using RankBrain and artificial intelligence and contextual information to deliver a search result? Jeremiah: Sure. I think something that's important to keep in mind when you're talking about this is the idea when we throw around the term 'artificial intelligence', we have a difficult time ... people dream up what artificial intelligence means on the spot. I think if you asked 10 people, their answers are going to be largely different. But really when we're using a rudimentary calculator, it is a form of artificial intelligence. It's just a very, very simple form of it, right? It's performing calculations that are very hard for you and me to perform in our minds for us right in front of us using simple inputs that were pre-programmed. It is an artificial machine. Google always has been, in some definitions, artificially intelligent. What we're going to see though is that Google is going to get so good at predicting what a user wants before the user requests it, that Google already is ready to serve that thing up and give it to them. They're going to do that by reading inputs and reading metrics ahead of time that we have given into Google to show them what we value. So Google's really following us and then forecasting out making predictions and then trying to provide that forecast right now so that it can get smarter. If we validate that forecast, then that checks one box over here for Google and they head more in that direction. If we invalidate it by scrolling through Google and not finding what we want, then they invalidate that forecast and they move a different direction. We're actually responsible for educating Google on all that and we do have to keep that in mind. That said, I think the best thing that you could do right now is if you've been playing the white hat SEO game all along, this is your renaissance. This is your chance to just really keep pushing hard with what you've always done because Google now has the system set up to especially reward that. What I mean by that is the way users are searching for things and engaging with content about their areas of interest and things that they find valuable is now going to become easier for them to do and easier for Google to reward those who provide a good experience for them. If you are genuinely producing good quality content, you know you are. You've been giving away the farm for years. You've been following the rules, you've been doing everything right, and you're still leaning forward. You're still being innovative, you're still pushing, you're trying to create new types of content, things like that.  You're going to start getting rewarded by watching competition disappear in search, the ones who are really trying to listen to their users in a human way, listen to your actual customers instead of surveys and things like that, have phone calls with them, listen to their pain points and stuff like that. By listening to that and then producing content, answering questions around it, doing it through social mediums that make the most sense to that audience, you're really going to be rewarded. One example I think of a company that's doing a very good job with that who's always done a very good job with SEO is Sierra Interactive. Will Reynolds has some really cool projects that he's worked on where they've done very deep, qualitative research into their clients' customer base to get a much better idea of what those customers value, what they're looking for, so that they know what they can provide in terms of content and experience and engagement on the site. Their clients have been massively rewarded with really good rankings, lots of good traffic, things like that from it. Kathleen: When you work with clients these days, are there certain things that you see when you go onto a new client's website that are really common items that should be addressed and that have been overlooked? I'm sure a lot of the companies you're working with have pretty good SEO fundamentals taken care of. They've got their meta titles and descriptions decently well-written. Their image sizes are compressed. I don't know, maybe they're not. What are the top five things that you're like, "Oh, that again"? Jeremiah: Yeah. That's a fantastic question. I've got to be honest, everyone's got a blind spot and nobody sees it better than the third point of view. Sometimes we are just in a beneficial position just because we aren't our client. If anyone was sitting in our position, they would have been better off to hire them as well as us. It doesn't matter. Just because we're the third point of view and we know what we know, we're able to help them with a lot of the blind spots. A lot of the stuff that we're seeing is actually stuff that ... well, for example in our industry, we tend to have SaaS companies are really, really good, I think, at simplicity to a large degree. We work with a lot of SaaS companies who are very lean, very simple, and I love that. They give us a very clean slate to work with. They are minimalist to a large degree. That can hurt you with SEO, but sometimes they understand that all that needs to be there is that which is valuable. So you look at their blog and you just find, wow, every article is very well-written. They only do one a month, but they're good pieces of content or something like that. That's not all the time, but what we often see though is that due to that minimalism, they're not honoring other elements that are actually going to serve their business. For example on that well-written blog, there is no way for me to engage deeper with your company or subscribe to your blog or to get some kind of a PDF download or to get something for giving you my email address. There's no offering, there's no carrot on a stick, there's no foot in the door offer. You're not trying to build a relationship with me, you're just showing me great content. I appreciate the great content. From an SEO perspective, that's awesome. Once the traffic gets there, what are they going to do? The only other option is for them to just decide, "Well, it's time for me to buy this." That is, as we know, not the case. People aren't just going to say "I want to buy this thing" right away, they want to get into a relationship. They want to progressively create buy-in. What we spend a lot of our times doing is actually suggesting stuff that's not directly related to SEO, but impacts it or impacts the results that make me look good. If I'm bringing traffic to your site but it doesn't move your company's revenue needle at all, you're going to fire us plain and simple. If instead, the traffic that's coming to your site stays the same and it gets higher quality and that moves your revenue, that looks good on us. If we can bring traffic to the site, it's higher quality traffic, but then we can show you how to convert that traffic into some kind of relationship, marketing or sales relationship, then the conversion rate really improves, then the revenue improves, and we really keep our job for the long haul. That's what we find ourselves doing most of the time is helping clients equip their sites to actually handle the traffic that we're going to send them. Sometimes by just putting that in place, they start getting conversions and they think we hit a magic button with SEO. We actually didn't do any SEO yet. We were just helping you get your funnels set up and then we're going to start doing the optimization and the improvements. Kathleen: Got it. How Will Screenless Voice Search Impact SEO? Kathleen: Now one of the big changes that I've been watching closely and I'm curious to get your thoughts on is the shift to screen-less search or voice search. I've got an Alexa. I've got actually two. Amazon Echo is in my house. One is called Alexa, one's called Echo. Jeremiah: Nice. Kathleen: We had to give them different names, otherwise everything starts going off at once now. When you think about ... and it's the same with Siri ... when you think about asking a voice search engine a question, really it seems like what we're moving in the direction of is search engines that only deliver one answer as opposed to the SERPs, which have delivered many, many answers and we can scroll through to find the best one. It feels like we're moving in the direction of letting the search engine do all that vetting and deliver us the one answer. What are your thoughts on that? How are you preparing your clients for that? What do you think is going to happen in voice? Jeremiah: Sure. We actually, luckily enough, get hardly anyone asking us about voice search for in regards to our clients asking us "We want to be prepared for voice search." It largely has to do with the industry that we're in. Our clients, there's hardly any commercial interest in voice search whatsoever for our target clientele. Now if you're out there and you are a pizza shop downtown or you're a restaurant in town or you're an oil change place or a plumber, an air conditioning company, something like that, voice search, I think is actually something you're gonna have to deal with at some point. And it is going to become more aggressive and there is going to be a future there but I don't think it's quite the final frontier that people that it is. I don't think that we're going to have a mass exodus from screen engagement into screenless engagement. I think it's just an additional feature, in the same way that the Amazon Kindle is to books. You know, you didn't get rid of books because we have the Kindle. Books still exist. You got a lot there, I got a lot over here, you know? Kathleen: Mm-hmm (affirmative). Jeremiah: But, I still use my Kindle a lot and I love using my Kindle, it's fantastic. It's a new feature so I think that we need to consider that when we're thinking about voice search, that it is just a new way to search but I don't think it's a replacement for search. Now, that said, I think that since it's an input, the output is what we're always looking for as searchers. We're looking for the result. Well, is the result that you're looking for, is it contextually relevant to a voice environment or a screen environment? For example, if I'm looking for E-commerce products, I'm not gonna do that on voice search, unless I know exactly what it is that I was and maybe it's a model number and I rattle it off and my Amazon device verifies that model number, puts it in a shopping cart then I'm fine with that. But even then I still feel a little uncomfortable. I kinda wanna see the picture so I know that it knows what I'm talking about, right? But when it comes to what time is it, what's the weather like, when is the next full moon, when is Mother's day, things like that, you have a lot less commercial opportunity there, you know? Like what kind of companies could make money off of those searches? That's what you have to think about and the reason you have to think about that is because search is a money making industry. 98% of Google's market cap is ads wrapped around their search results. It's advertising. So on a voice search, if I asked for something am I gonna have to hear two or three ads spoken to me before I get to my result? Because if I am I'm not gonna be asking that machine a lot of questions, right? That's gonna drive me nuts. And if I don't hear a bunch of ads then who's making money off of that search, right? So you do have to think about that. However, pizza shop in town, A/C company, plumber, those kinds of guys I think are gonna have to deal with the fact that a lot of people are gonna start talking to their Amazon devices and using voice search to take care of almost like personal assistant tasks in a way and so that kind of stuff there is commercial intent for. The pizza shop in town's gonna have to find a way to get into whatever database Amazon considers important or Siri considers important when they go doing those voice searches and getting into those databases and playing with those algorithms because Amazon has usurped Bing and Yahoo as the second largest search engine. Kathleen: Yeah. Jeremiah: And so they're now up against Google and we have to keep that in mind. We talk to Google, we talk to Windows machines, Siri machines, Amazon machines. We now have all these new search engines that we get to optimize for based on what industry you're in. But again, I think it all goes back to commercial intent. Kathleen: Yeah. And side note, if you are an Alexa user, this podcast has an Alexa skill so you can go into the skills in your app and search for "inbound success" and you will find it there, if you want to hear these kinds of conversations once a week coming out of your Alexa. It's interesting. I don't know how that's going to do. I figured go play around and put it in there but it'll be interesting how many people actually listen to it. Jeremiah: Yeah. Kathleen: So I'm curious. In terms of delivering that one result I feel like the corollary on a computer to the voice search is Google Featured Snippets or what people are calling "position zero." Are you working with any clients on how to optimize for the Featured Snippet or for position zero? And also, have you seen your clients lose any organic traffic to position zero? Jeremiah: Yeah, yeah. So we've run into some interesting situations with the whole position zero thing. We've had a couple of clients perform well in that space, a couple of pieces of content that we wrote for them got picked and converted into those Featured Snippets and that's always like high fives all around the agency whenever that happens because we're like, "Look at this thing!" because that's completely automatic. Google is like, "Hey, we will decide if we are going to use that or not." And you really have to throw them something good for them to put it up there because they're trusting you with so much when they just say, "Yeah, here's what this one guy says is the answer to the problem of Google here." Kathleen: Yeah. Jeremiah: And so that's a big deal but at the same time we're finding that yeah, sometimes we do lose a little traffic to Featured Snippet results but I don't know that it's the best traffic that we're losing. Because, for example, some of our clients are actually, if they're considering, like for example, a SaaS product, they're gonna do a lot of research, they're gonna dig around and they're gonna make a decision after forging a relationship with someone. That quick little answer may have helped them for a brief moment but if that's all they needed then they're actually not the client that we wanted in our case. Now that's just us and that's our typical client. That's not everyone. So I totally understand that's not a blanket application there but I would say that, that's something to consider. That's something to keep in mind. Google ultimately thinks that by providing such a clear, simple result like that, that it's going to help users have better engagement with Google. But what we also have to keep in mind is how does that serve Google, right? In the long run, the idea there is if we give a good enough experience to the user then they will trust Google more, they'll use Google more and later on they may click an ad. But it's not all gonna go to this zero search result because if it did then when would people ever click on an ad? And Google would never make money again and now they're a non-profit search engine. That doesn't make sense, right? Kathleen: Right. Jeremiah: So I don't see them going that direction either. And I feel like I sound cynical talking about it like this but I just understand the direction of commerce so much that when something like that works well it's almost like a loss leader where they're trying to give us something to keep using Google but they really want us to go click on some ads, you know, once we get there. Kathleen: Yeah, I mean they're a business too. Jeremiah: Right. Kathleen: It's easy to forget that Google's a business too and they are in a competitive landscape and they have to stay on top. Jeremiah: Right, right. Kathleen: It makes sense. Jeremiah: Yup. They're not a free public utility. Kathleen: Yeah. I feel like I could spend literally hours asking you all of the SEO questions I have in my head that I want answers to but we have limited time and so I wanna make sure that I squeeze in the two questions I always like to ask every guest. Jeremiah: Sure. Kathleen's Two Questions Kathleen: Just to get perspective. So taking a step back, you work with a lot of different companies. You obviously follow a lot of thought leaders online, you mentioned Brian Dean. Company or individual, who do you think is doing inbound marketing really well right now? Who would you point to as the best practice? Jeremiah: I actually have several, to be honest. First of all, I wanna say I genuinely and without patronizing I genuinely think you guys are awesome. I've seen a lot of the work that you guys produce and everything at Impact and I'm blown away at just how simple and clean you guys make things sometimes. Kathleen: Aw, thank you. Jeremiah: I like good, clean execution of the inbound marketing methodology and you guys just do a rockstar job of that. It's so cool. Kathleen: Thank you. Jeremiah: Kudos to you guys on that. I think a couple of others that I'm crazy about that kind of come from my SEO industry and just like deep SEO nerds that have over time evolved as leaders, not just in SEO but in marketing in general and I've followed them from day one, would be Distilled and Seer Interactive. I really like what the guys do at those companies. Distilled, I'm really interested in the fact that they've got this, I think they call it, their optimization distribution network or ODN, and they're constantly using their own artificial intelligence to test their results against Google to see what they're doing for clients works best and then going that direction. So smart and so brilliant. Kathleen: Distilled has some pretty cool training programs too you can enroll in online if you wanna learn more. Jeremiah: Yeah. We've got our team, we have an account with them, Distilled U, and our whole team's gone through. We love Distilled. They're very cool guys. They give away a lot of cool stuff. And I know some people from there too, really good people. Kathleen: Yeah. Jeremiah: And then Seer Interactive, I really love them. Where Distilled might be that data heavy, data focused kind of side of things - I don't know if you'd call that right brain - Will is almost like the opposite, like left brain. I'm not saying he doesn't use data, he uses data too but he's kind of got this gut and he goes with his gut a lot and you just kind of see his ideas just work and they come off just as well in my opinion as Distilled. So when I look at the two of them, I'm like, "They're behemoths in my industry." I really love what they're doing, so. Kathleen: Yeah, it's like how can I combine the two? Jeremiah: Yeah. Kathleen: And master the world! Jeremiah: Right. Kathleen: I love it. Jeremiah: Seriously. Kathleen: Well, those are two really good ones for people to go check out. Jeremiah: Mm-hmm (affirmative). Kathleen: And, you know, what we've talked today, it's such a great example of how quickly digital marketing is changing. I feel its sort of like when you go to the grocery store and they've rearranged the aisles and you don't know where to find the milk. Jeremiah: Mm-hmm (affirmative). Kathleen: I feel like SEO is like that but like, so much faster. It's like they're rearranging the aisles every week or every day. Jeremiah: Yeah. Kathleen: How do you stay up to date? How do you educate yourself so you're on top of all that stuff? Jeremiah: Good question. In every space, everyone always says experience matters the most. I think in SEO, once you have two or three years under your belt of SEO experience and you stick with it and you just stay with it, you start to pick up the patterns and the trends that make sense ahead of time, where you can see. That's definitely gonna matter and this is definitely not like what people are talking about over here. It's not a huge concern. And that takes a while to develop that taste and that sense. When I first got started, Moz was it and back then SEO Moz, they were the ones that I looked to for everything SEO related. Search Engine Land, I followed as the news update there. And then over time I kind of got used to seeing things on my own that I wasn't as much going outside to get information as I was running our own tests internally and being like, "Well, I know what's happening here. I don't even need to ask someone else about it." And then I became kind of a thought leader and speaker on it, where now I'm telling people about it so it's a little odd. So kind of a flip, but I would say pay attention to the common core elements that are important in marketing all the time and you will know what really matters when people starting yelling "the sky is falling, SEO's over, here's the next big thing" and that kind of thing. You'll know what to do in those moments and you won't have that knee jerk reaction to do every new thing and wake up in cold sweats in the middle of the night because you're not using Drift or whatever. You'll be okay when you figure those core things out. Kathleen: Yeah. I'm a big fan of - and I'm not a professional SEO, I mean, I need to know about a lot for my job - but I've become a big fan of just reading the Google Webmaster Central blog. Jeremiah: Mm-hmm (affirmative). Kathleen: Just because it's quick, it's easy. They're short posts and if you can keep up with it, it's a great way to just know at least what they're focused on as well. Jeremiah: Right. And I would say that is definitely Gospel. Whatever you're hearing what Google is saying, they're usually serious about that and there are a few guys out there who will call them out publicly and say, "That's not what's happening. I got results to prove it." So if you know those guys and Google Webmaster Central I think you got all your bases covered. You'll be set. Kathleen: Yeah. I feel like Rand Fishkin is one of those guys. Jeremiah: He is. Kathleen: I always feel like he's like "Google, you're not telling the truth." Jeremiah: Right, right. Yep, I love that about him. Kathleen: Yeah. Awesome. Well, this has been so interesting. I love that you came and shared all this knowledge. I'm sure there are going to be people listening who have questions and wanna go deeper into some of this SEO stuff. How can they get in touch with you? What's the best way to find you online? Jeremiah: Sure, they can shoot me an email at jeremiah@simpletiger.com or they can just check out our website. We've got a lot of content on there. We've got Drift set up, so if you want to start a conversation, we'll be right there. If I'm on Slack that day, I'll answer right away. But yeah, they can just check us out. We love talking about this stuff and if anybody's interested in just getting a little bit of help or wants to dive in to some of the problems they may be having, then they can get in touch with us for that too. Kathleen: Great. I'll put those links in the show notes. Jeremiah: Awesome. Kathleen: Well, if you're listening and you found value in this interview, please consider giving the podcast a review on iTunes, Stitcher or the platform of your choice. It's super helpful for us in terms of getting in front of new and interested audiences so that's a favor I'm gonna ask if you're a listener. Go and leave us a five star review and if you know somebody who's doing kick ass inbound marketing tweet me @workmommywork because I'd love to interview them. And that's it for this week. Thank you so much, Jeremiah. Jeremiah: Thank you so much for having me. I really enjoyed it and I hope I provide a little bit of value here. So thank you for having me. Kathleen: Oh, definitely. This was fun and I learned a lot.

Intro 0:00:00 News 0:03:40 DOT Swap 0:03:40 S Korea ICO News 0:05:35 SEC Charges An ICO With Fraud 0:06:36 Segwit 2X Upcoming 0:08:51 Markets 0:10:37 DOT Giveaways 0:21:23 Coin Listings 0:23:37 Cryptopia(MCI, COR, HAC, HDLB, KNC, SPR, QWARK, APX, ODN, RUP, HSR, BIS) 0:24:59 Bittrex(ADA) 0:30:51 Novaexchange(BTCX, VOLKS, CAN, VEGA, A3M, BSDB, SIM, GNB, COLX, TZC, SCOOBY) 0:31:10 Coinexchange.io(LRC, ALIS, TBS, RBL, REC) 0:33:19 Liqui(SALT) 0:34:19 Coin Birthdays 0:35:46 ZCoin - 1 year 0:35:58 Haloween Coin - 1 year 0:36:30 Outro 0:37:12

Since we're ready for ODN, what better time to talk with Kelly Springer than right now. Kelly actually is on the track as he's talking with us and he gives us a good rundown off all the changes made to the track and what the skaters can look forward to. Thanks Kelly for taking the time to join us! Skate Talk with Boomer and the Coach is powered by Pinnacle Racing. If you're at ODN, make sure you look for Jimmy Blair and Pinnacle Racing. He's super easy to find online as well, just hit up pinnacleracing.com. Skate your best. Skate in Pinnacle!

This month’s DoODcast is dedicated to an interview with Matt Minahan, Chair of ODN. Paul & Karen spent time chatting with Matt, finding out about his role at ODN and the new Global Competency Model that they’re working on. We found out a few surprises about Matt along the way!

It's time for the Summer of Love, we have meetups and turf wars all over the place, and we talk about Spreaadsheeets in Spaaace... All that and more coming up right now. THIS is the AIE Podcast... AIE NEWS We have a new officer cornered, I mean, we have a new officer in the officer's corner! Head on over to the forums to ask those burning questions to our very own amazing exploding Tuku! No question too hard, ask just about anything you want, today! Holy cow FAN ART! We want to give a big shout out and thanks to Fen, who created an amazing drawing of our WoW characters. I don't even know what to say, this is really really incredible. http://forum.myextralife.com/topic/46300-for-the-aie-podcasters/ Plans for DragonCon 2012 are shaping up! As usual, we will have an AIE meetup at the Loft Bar in the Marriott hotel, and this year we will also be conducting a panel on Guild Leadership, where we will show off some of the tools we use behind the scenes to manage AIE. If you're going to be at DragonCon, we'd love to see you there. Make sure to check both the Meetup.com site and the forums for updates on this and other events going on at DragonCon this year. One of our own is now involved in a turf war....with one of our own?! What is this guild coming to? You heard it on ODN, it must be true! Weigh in on the battle on the forums in the thread ‘addressing the rumors between myself and Alludra' started by Old man Franks. Alludra would like to go on record saying ‘I have an army and you don't. Nyah!' AIE raid on Chino Banditos is happening this Friday in Phoenix Arizona! If you happen to be in the area, consider dropping by at what is sure to be a memorable AIE meetup event! Details can be found in both the forums and in the meetup.com website. World of Warcraft has released a new recruit a friend mount! The new Obsidian nightwing mount, has officially taken the place of the X-53 touring Rocket as the recruit a friend reward. This new mount, instead of being a two seater or personal mount, transforms the owner into a black winged cat! Details about how to obtain the mount and images of it in action can be found on the world of warcraft website. Pet battles are live on the beta! Now you can begin the testing on how best to train up your own personal army! The new in game system is a bit on the buggy side and is still new, but that's what betas are for! Log in and check it out if you are interested in giving this system a run! (It's really a lot of fun...when it is working!) Rift is in its second week of the summer sun celebration! Log into your free Rift Lite account to check out the new content and fun event which includes all new dailies, quests, pets, and titles! Rift has also released a new tiger mount for the low low price of $15! Steam summer sale! In case you didn't know, steam is having it's annual summer sale! The sale, with discounts as low as 75% off most titles, will be running through the 22nd! Steam itself is free, and has a host of free games available for all (including TF2), but right now is a great time to score that title you have been eyeing but could never quite afford. Summer of Love Currently the AIE guilds of World of Warcraft and StarWars The Old Republic  are planning Summer of love events on July 29th through August 4th. Check out their respective forum posts for more details about the in game events planned for the celebration. Tak who is lending a hand with the fireworks this year is also looking for volunteers and donations to make our remembrance day spectacular, if you would like to help, check out his forum post Request for help: AIE remembrance day fireworks tribute. And with that, let's welcome this week's guests Louis from AIEU and Lanctharus from Taxil Transtellar. GAME NEWS AIEU Happenings Welcome new blood!  Lots of new people now,  so many I don't even know who is who anymore. Delve War update SoCo folded like a cheap suit

Hintergrund und Ziele der Arbeit: Bakterien und DNA Viren werden anhand unmethylierter CpG-Motive innerhalb ihrer DNA von den TLR 9 tragenden PDCs und den B Zellen des humanen Immunsystems als Gefahrensignale erkannt. Mittels synthetischer, CpG-enthaltender ODN nutzt man diese Grundsatzmechanismen, um vergleichbare Immunantworten auszulösen. Auf Grundlage eines unterschiedlichen immunologischen Aktivierungsprofils wurden bislang drei CpG-Klassen definiert: CpG-A, CpG-B und CpG-C. Mit Hilfe von CpG-A war es erstmals möglich, IFN-α in PDCs (den endogenen Hauptproduzenten dieses Zytokins) in Mengen zu induzieren, wie es bislang nur mit Viren selbst möglich war. Auch CpG-C stimuliert PDCs zur Sekretion von IFN α und aktiviert darüber hinaus B Zellen - eine Eigenschaft, die CpG-A nicht besitzt. Die sequenzspezifischen und strukturellen Voraussetzungen für diese differenziellen Wirkprofile waren bislang unzureichend verstanden, auch weil die Struktur-Analysen nur begrenzt auf die tatsächlichen Vorgänge im physiologischen Milieu übertragbar waren. Um CpG-ODN für die therapeutische Anwendung zu optimieren, sind die genauen Kenntnisse der Struktur-Wirkungsbeziehungen jedoch unverzichtbar. Ein zweiter Ansatzpunkt zur Optimierung der Anwendung liegt in der Verbesserung der systemischen Stabilität von CpG-ODN. Die Bindung von CpG-ODN an partikuläre Trägersysteme (z.B. Gelatine-Nanopartikel) wurde bereits in unserer Abteiliung als mögliches drug-delivery-System etabliert. Eine Weiterentwicklung dieses Prinzips wären partikuläre Strukturen, die aus immunstimulatorischen Nukleinsäuren aufgebaut keiner weiteren Trägermaterialien bedürfen. Beide Ansatzpunkte führen zu den Zielen dieser Arbeit: 1) Die Aufklärung der Struktur-Wirkungsbeziehungen der CpG-Klassen A und C durch Etablierung geeigneter Methoden zur Untersuchung im physiologischen Milieu. 2) Die Entwicklung immunstimulatorischer partikulärer Strukturen auf Basis der in Teil 1) identifizierten wirksamen Strukturelemente beider CpG-Klassen. Ergebnisse: 1) Struktur-Wirkungsbeziehungen von ODN 2216 (CpG-A) und ODN M362 (CpG-C): CpG-A bildet im physiologischen Milieu spontan multimolekulare Strukturen, deren mittlere Durchmesser mit 24 40 nm im Größenbereich von Viren liegen. Es zeigte sich, dass für diese Multimerisierungen das Zusammenspiel aus flankierenden Poly-G-Motiven, palindromischem Zentrum und eingelagerten Natrium- oder Kaliumionen entscheidend ist. Physiologisches Milieu wirkt sich sowohl den Umgebungs-pH und die Na+/K+-Konzentrationen als auch die Temperatur (37 °C) betreffend optimal förderlich auf die Strukturbildung aus. Die Identifizierung dieser maßgeblichen Faktoren machte es möglich, den Strukturaufbau von CpG-A experimentell zu kontrollieren und die immunologischen Wirkungen der verschiedenen Strukturen direkt zu vergleichen. Für die rasche und hohe Induktion von IFN-α und anderen inflammatorischen Zytokinen durch PDCs sind große Partikel verantwortlich. Die Multimerisierungen von ODN 2216 werden bei pH < 6 zunehmend aufgehoben. Unterbindet man die Multimerisierungen durch Präinkubation der ODN bei Temperaturen > 60 °C oder durch Entzug der stabilisierenden Natriumionen (indem man sie zuvor in Aqua ad inj. löst), so verliert ODN 2216 seine immunstimulatorische Aktivität in Bezug auf PDCs. Die schwache Wirkung der CpG-A-Monomere kann jedoch durch Präinkubation von PDCs mit IFN β deutlich gesteigert werden. Im Gegensatz zu den ebenfalls einzelsträngig vorliegenden ODN 2006 (CpG-B) haben auch Monomere von ODN 2216 keine aktivierende Wirkung auf B Zellen. CpG-C hat durch die palindromische Sequenz die Möglichkeit, Hairpins und Duplices zu bilden. ODN M362 zeigt jedoch keine Hairpinstrukturen. Die Duplexformationen sind bei 37 °C in vitro nicht stabil und spielen keine Rolle bei der durch diese ODN initiierten B-Zell-Aktivierung. Duplices haben jedoch Anteil an der Induktion von IFN-α in PDCs. Die in dieser Arbeit etablierten Protokolle der Temperatur-Präinkubation ermöglichen erstmalig eine experimentelle Kontrolle der Strukturbildungen von CpG-A und CpG-C und dadurch den Vergleich von Struktur und Wirkung. Das Standardprotokoll für Gelelektrophorese wurde dahingehend modifiziert, dass ein physiologisches Milieu sowohl durch die anwesenden Ionen als auch durch die Umgebungstemperatur (37°C) simuliert werden konnte. 2)Design Nukleinsäure-basierter Nanopartikel: Zentrale Elemente von CpG-A und CpG-C (palindromische Sequenz, gerüstartige Verbindung mehrerer Nukleinsäuren) wurden eingesetzt, indem ODN M362-Sequenzen (CpG-C) an bi- und trivalenten Grundgerüsten (Linkern) für den Strukturaufbau optimiert wurden. Trivalente Linker ermöglichen die variierende Zusammenlagerung der palindromischen Nukleinsäuren in drei Richtungen des Raumes und dadurch die Bildung großer Partikel. Diese sind den bisher bekannten Maximalstimuli CpG-B und CpG-C hinsichtlich der Aktivierung von B-Zellen gleichwertig. Erstmalig konnten auf diese Weise B-Zellen durch partikuläre Strukturen stark aktiviert werden. Nach Vor-Komplexierung der Partikel mit Poly-L-Arginin wird die Aktivität bei B-Zellen nochmals verstärkt. Kurze, nicht-palindromische CpG-DNA-Sequenzen an trivalenten Grundgerüsten induzieren nach Vor-Komplexierung mit Poly-L-Arginin deutlich mehr IFN-α in PBMCs als CpG-A, obwohl sie selbst nicht multimerisieren. Wird die (palindromische) RNA-Sequenz von CpG-C an einem trivalenten Linker verwendet, so können ebenfalls große Strukturen generiert werden, die nach Transfektion vergleichbare Mengen IFN-α in PBMCs induzieren wie CpG-A. Ausblick: Die vorliegende Dissertation verbindet Fragestellungen der Immunologie und der pharmazeutischen Technologie mit den Möglichkeiten der Biochemie. Es werden nicht nur verschiedene Methoden zur strukturellen Untersuchung von CpG-ODN im physiologischen Milieu etabliert, sondern auch die experimentelle Kontrolle der Strukturbildung von CpG-A ermöglicht. Die entwickelte Technik der Generierung dreidimensionaler, über palindromische Nukleinsäuren aufgebauter Partikel ist nicht auf CpG-Motive in DNA begrenzt, sondern kann auf eine andere für Viren charakteristische Nukleinsäure (Einzelstrang-RNA) übertragen werden. Dadurch würde zusätzlich möglich, die immunologischen Profile von ssRNA, dsRNA und CpG in einem Partikel zu kombinieren und die Art der Immunantwort je nach Zusammensetzung der Partikel gezielt zu bestimmen. Die klinische Relevanz dieser Arbeit ergibt sich aus den neuen Erkenntnissen über die Multimerisierungen von CpG-A, welche dessen therapeutischen Einsatz optimieren und besser standardisierbar machen sollen. Außerdem werden neue Hinweise auf die unterschiedlichen Aufnahme- und Erkennungsmechanismen beider CpG-Klassen und deren Aktivierung der Synthese von IFN-α gewonnen. Darüber hinaus wurde durch die Entwicklung der Polyvalenten Linker eine grundsätzlich neue Technik im Stil eines Baukastensystems etabliert, welche als Grundstein einer neuen Generation von immunstimulatorischen Multimeren dienen soll. Die Koadministration von Adjuvans und Antigen in direkter räumlicher Nähe bietet neue Gestaltungsmöglichkeiten in der Vakzineentwicklung. Zudem ist zu erwarten, dass unter Einbeziehung der RNA basierten immunologischen Wirkprofile innerhalb eines Partikels der Einsatz von CpG-ODN zur Therapie von Virusinfektionen und Tumoren weiter verbessert werden kann.

Die beiden Pathogen-assoziierten molekularen Muster, CpG-Oligonukleotide, als Imitate bakterieller DNA, und LPS, sind in der Lage, das menschliche Immunsystem zu stimulieren. Vor Entdeckung der Toll-like Rezeptoren konnte nicht zwischen direkten und indirekten Effekten von CpG-Oligonukleotiden und LPS auf Zellen des menschlichen Immunsystems unterschieden werden. Durch die Entdeckung der Toll-like Rezeptoren und vor allem die Charakterisierung von TLR9 als Rezeptor für CpG und TLR4 als Rezeptor für LPS entstand die Möglichkeit, die Zielzellen von PAMPs an Hand der Expression der dazugehörigen Rezeptoren zu definieren. Dendritische Zellen sind im Immunsystem des Menschen essenziell für die Auslösung einer Immunantwort. Sie sind in der Lage, eindringende Pathogene an Hand von PAMPs schnell und sicher zu erkennen, und daraufhin eine passende Immunantwort zu initiieren. Zwei Subpopulationen von dendritischen Zellen konnten kürzlich im peripheren Blut identifiziert werden: Plasmazytoide dendritische Zellen (PDC) und myeloide dendritische Zellen (MDC). In der vorliegenden Arbeit wurden die Unterschiede zwischen PDC und MDC in ihren Reaktionen auf CpG-Oligonukleotide, LPS und CD40 Ligand charakterisiert. Funktionelle Untersuchungen zeigten, dass nur PDC und nicht MDC direkte Zielzellen von CpG-ODN im humanen Immunsystem darstellen, während LPS MDC aktiviert, jedoch nicht PDC. Damit konsistent konnte auf molekularbiologischer Ebene nachgewiesen werden, dass PDC TLR9 exprimieren, jedoch nicht TLR4, während MDC den für die Erkennung von LPS notwendigen Rezeptor TLR4 besitzen, aber TLR9 nicht exprimieren. In gemischten Populationen reagierten auch myeloide dendritische Zellen auf CpG-Oligodesoxynukleotide, was auf eine indirekte Aktivierung durch plasmazytoide dendritische Zellen hinweist. PDC reagierten nach Stimulation mit ODN 2006 mit einer Hochregulation von Reifemarkern und kostimulatorischer Moleküle, der Expression von Chemokinrezeptoren, der Produktion proinflammatorischer Chemokine und einer verminderten Apoptoserate. Nach Stimulation mit ODN 2216 sezernierten sie große Mengen IFN-α, während ODN 2006 für die Induktion von IFN-α eine Kostimulation mit CD40 Ligand benötigte. Weder ODN 2006, ODN 2216 oder CD40 Ligand alleine waren in der Lage, IL-12 in PDC zu induzieren, die synergistische Stimulation von PDC mit CpG-ODN und CD40 Ligand führen jedoch zur Produktion großer Mengen an IL-12. Unter optimaler Stimulation mit ODN 2006 und CD40 Ligand können PDC damit gleichzeitig IL-12 und IFN-α produzieren. Das Verhältnis der produzierten Zytokine ist dabei abhängig vom Differenzierungsgrad der PDC. Durch zunehmende Ausreifung der PDC mit IL-3 verschiebt sich nach der Stimulation das Produktionsverhältnis an sezernierten Zytokinen zugunsten von IL-12. Ausreifung mit ODN 2006 ermöglicht PDC, zudem naive allogene CD4 Zellen zu aktivieren, und induziert in Kokulturen IL-12-abhängig ein Th1-gerichtetes Zytokinprofil in den CD4 T-Zellen. IFN-α schien dabei eine geringe Rolle zu spielen. Durch die Charakterisierung der PDC als TLR9-tragende Zielzelle für CpG-DNA, trägt diese Arbeit entscheidend dazu bei, die PDC als Schlüsselzelle für die physiologischen Wirkungen von TLR9-Liganden zu identifizieren und zu verstehen. Dies ist von hoher Relevanz für die Entwicklung therapeutischer Anwendungen von CpG-ODN in der Tumortherapie, Asthmabehandlung, Infektionsprophylaxe und als Adjuvans bei Impfungen.

In der vorliegenden Arbeit wurden die diffusiven und elektrophoretischen Eigenschaften von Desoxyribonuklein-säure (DNA) und die Selbstassemblierung von DNA-Chromophor-Hybridmolekülen untersucht. Hierzu wurden, neben Gelelektrophorese und temperaturabhängigen Absorptionsmessungen, vor allem Fluoreszenz-Korre-lationsmethoden angewandt. Um quantitative Aussagen mittels Fluoreszenz-Korrelations-Spektroskopie (FCS) über die freie Diffusion von doppelsträngigen (ds) DNA-Fragmenten (75 bp - 1019 bp) in wässrigen Lösungen zu treffen, wurden laserleis-tungsabhängige Messungen durchgeführt. Diese Experimente ergaben, dass photophysikalische Effekte wie Triplettrelaxation, Isomerisations- oder Bleichprozesse die Autokorrelation entscheidend beeinflussen. Die Län-genabhängigkeit der gemessenen Diffusionskonstanten kann mit einem Stabmodell beschrieben werden, das für alle verwendeten dsDNA-Fragmente, die Konturlängen von bis zu 7 Persistenzlängen aufweisen, Gültigkeit besitzt. In diesem Zusammenhang konnte auch gezeigt werden, dass kleinere Diffusionskonstanten lediglich bei der Zuga-be von zweiwertigen Salzen und bei hohen Salzstärken (> 0,1 M) beobachtet werden. Durch eine Komplexierung der dsDNA-Fragmente mit kationischen und neutralen Lipiden war es möglich, dsDNA in ein unpolares Lösungs-mittel (n-Alkan) zu überführen. Durch Messung der freien Diffusion konnte die Monodispersität von Lipid-dekorierten dsDNA-Fragmenten festgestellt werden. In der unpolaren Phase wurde eine kritische DNA-Konzentration (≈ 10 nM) festgestellt, die für die Stabilität der DNA-Lipid-Komplexe notwendig ist. In der Arbeitsgruppe von Prof. Dr. Müllen am Max-Planck-Institut für Polymerforschung in Mainz wurde ein DNA-Chromophor-Hybrid synthetisiert, bei dem an ein zentrales Farbstoffmolekül (Perylen) beidseitig jeweils ein kurzes ca. 20 Basen langes Oligonukleotid (ODN) kovalent angebunden wurde. FCS-Messungen, die die intrinsi-schen Fluoreszenzeigenschaften des Hybrids ausnutzten, konnten die Löslichkeit und Monodispersität der Hybride bzw. der Lipid-Hybrid-Komplexe sowohl in wässriger Phase als auch in Alkanen nachweisen. Durch eine geeigne-te Wahl der ODN-Sequenzen und der Anknüpfungsstelle der ODN an den Farbstoffkern entstanden durch Basen-paarung unterschiedliche, supramolekulare Strukturen, die in Gelelektrophorese-Experimenten nachgewiesen wur-den. Symmetrische DNA-Chromophor-Hybride können neben beliebig langen, linearen Ketten bei entsprechender Modifikation der Bausteine sandwichartige Dimere ausbilden. Asymmetrische Hybride ermöglichen den Aufbau linearer Strukturen definierter Länge (z. B. Dimere). Die thermodynamischen Eigenschaften der unterschiedlichen, supramolekularen Konstrukte wurden durch tempe-raturabhängige Absorptionsexperimente untersucht. Die Denaturierung der linearen kettenartigen Strukturen kann durch ein Zwei-Zustands-Modell beschrieben werden, dessen energetische Eigenschaften sehr gut mit denen der verwendeten ODN übereinstimmen. Im Fall der sandwichartigen Strukturen musste für den Schmelzübergang ein Drei-Zustands-Modell angenommen werden, wobei die eingebauten Farbstoffkerne eine energetische Wechselwir-kung vermittelten. Neben der freien Diffusion von dsDNA wurde deren elektrophoretische Drift untersucht. Dazu wurde ein Mikroe-lektrophorese-System entwickelt, bei dem die Drift im elektrischen Feld mittels zweier Laserfoki detektiert wird, die einen Abstand von ca. 5 µm aufweisen. Hierbei wirken die beiden Foki wie eine mikroskopische „Lichtschran-ke“; die Driftzeit wird dabei durch eine Orts-Orts-Kreuzkorrelation der beiden Fluoreszenzsignale zugänglich ge-macht. Auf Grund der methodisch bedingten sehr hohen Ortsauflösung ist es möglich, detaillierte Aussagen über die elektrophoretischen und elektroosmotischen Anteile an der Drift zu treffen. Experimente mit unterschiedlichen Feldstärken zeigen, dass eine Temperaturänderung durch den Eintrag von Joulscher Wärme nicht vernachlässigbar ist. Die elektrophoretische Mobilität ist in freier Lösung bei der verwendeten dsDNA unabhängig von der Frag-mentlänge und beträgt im Mittel 4,5∙10-4 cm2/Vs. Durch die gleichzeitige Messung von Drift und Diffusion konnte neben der elektrophoretischen Mobilität der dsDNA-Fragmente auch der Einfluss der hydrodynamischen Reibung ermittelt werden. Dadurch zeigt sich, dass neben der elektrostatischen Kraft und der Reibungskraft auch hydrody-namische Abschirmeffekte berücksichtigt werden müssen, um mit einem entsprechenden Kraftbild die Elektropho-rese-Experimente zu erklären. Im Gegensatz zu den Messungen in freier Lösung zeigt die elektrophoretische Drift der dsDNA-Fragmente in ei-nem physikalischen Polyethylenoxid-Netzwerk eine Längenabhängigkeit, die einem Potenzgesetz folgt (exp=-0,3). Berechnet man das Auflösungspotential der Elektrophorese-Experimente und vergleicht dies mit theoretischen Vorhersagen, so ergibt sich, dass die Diffusion im Vergleich zur Detektorausdehnung den deutlich stärker limitie-renden Faktor bezüglich des Auftrennpotentials unterschiedlich langer DNA darstellt. Die Auftrennung unter-schiedlich langer dsDNA-Fragmente in der Lösung konnte experimentell nachgewiesen werden, wobei die Auflö-sungsgrenze ungefähr 400 bp betrug. Die vorgestellten Ergebnisse belegen, dass FCS zur quantitativen Charakterisierung der Diffusion eingesetzt wer-den kann. Darüber hinaus erlaubt die simultane Messung von elektrophoretischer Drift und Diffusion mit Hilfe von Doppelfokus-FCS, die Bildung von supramolekularen Konstrukten im Bezug auf Ladung und Geometrie mit einer Zeitauflösung im Minutenbereich zu verfolgen.