Podcasts about clinical lipidology

The Omega-3 Index and Fun Approaches to Fitness: Nutritionist Leyla Muedin discusses the significance of the Omega-3 index as an independent risk factor for cardiovascular disease, comparable to cholesterol and smoking. She highlights the findings of a study published in the Journal of Clinical Lipidology, emphasizing the importance of increasing intake of marine Omega-3s. Leyla also shares practical advice on affordable ways to boost Omega-3 levels and minimize mercury exposure. Additionally, she offers tips on making fitness enjoyable through activities like hiking, swimming, roller skating, dancing, and playing sports.

Today, I am excited to share the first class in a series of lipid masterclasses with the amazing Dr. Thomas Dayspring! Dr. Dayspring is certified in internal medicine and clinical epidemiology and is a fellow of the American College of Physicians and the National Lipid Association. He was previously the Educational Director of a nonprofit organization and has served as the Chief Academic Advisor for two major cardiovascular labs.  Due to the in-depth nature of my discussions with Dr. Dayspring over several sessions, each lasting nearly six hours, it seemed logical to present these masterclasses in segmented chunks to make them easier to understand. In our first class today, we dive into the fundamentals, exploring what lipids are and how lipids and fatty acids are classified. We cover the physiology and transportation of cholesterol and the role of apoptosis, apo-proteins, and apo-lipoproteins, unravel the differences between HDL, LDL, IDL, and VLDL, and explain how to calculate LDLs and triglycerides for assessing metabolic health. Dr. Dayspring also shares his preferences regarding lab values and the indicators that provide information to help him determine the early risk of cardiovascular disease. We get into some detailed aspects of physical chemistry in this episode, so I highlight the main clinical points throughout our conversation to make it more understandable. Be sure to join Dr. Dayspring and me for our next episode in the lipid masterclass series. IN THIS EPISODE YOU WILL LEARN: What are lipids, and why are they important? Dr. Dayspring explains what triglycerides are. How lipids get absorbed and transported throughout the body What lipoproteins are, and how they get classified How cholesterols get calculated The impact of triglycerides on cholesterol levels and cardiovascular health How high triglyceride levels can indicate early insulin resistance or increased ASCVD risk What is the role of HDL particles? How metabolic syndrome impacts cardiovascular health Bio: Thomas Dayspring MD is a Fellow of both the American College of Physicians and the National Lipid Association and is certified in internal medicine and clinical lipidology. After practicing in New Jersey for 37 years, in 2012, he moved to Virginia. He served as an educational director for a nonprofit cardiovascular foundation and until mid-2019 as a Chief Academic Advisor for two major CV laboratories. Since then, he has served as a virtual cardiovascular / lipidology educator. Career-wise he has given over 4000 domestic (in all 50 states) and several international lectures, including over 600 CME programs on atherothrombosis, lipids/lipoproteins (and their treatment), vascular biology, biomarker testing, and women's cardiovascular issues. He has authored several manuscripts and lipid textbook chapters and performed several podcasts. For several years he was an Associate Editor of the Journal of Clinical Lipidology. He was the recipient of the 2011 National Lipid Association's Presidents Award for services to clinical lipidology and the 2023 Foundation of NLA Clinician/Educator Award. He has over 34K followers on his educational Twitter (X) feed (@Drlipid). He has Gold Heart Member status as a professional member of the American Heart Association and serves as a Social Media Ambassador for the European Atherosclerosis Society and the National Lipid Association. Connect with Cynthia Thurlow Follow on Twitter, Instagram & LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Connect with Dr. Thomas Dayspring Twitter (@DrLipid) LinkedIn

I am thrilled to present the last class of our Lipid Masterclass series today with the esteemed Dr. Thomas Dayspring. Dr. Dayspring is board-certified in internal medicine and clinical lipidology and is a fellow of the American College of Physicians and the National Lipid Association.  Today, we round things out by diving into medications for lipid abnormalities and discussing lipid physiology, with Dr. Dayspring shedding light on insulin resistance and statins and cautioning against statin use for those predisposed to diabetes or insulin resistance. He also explains why LDL particle size is not worth testing and discusses ways to identify specific laboratory abnormalities.  Be sure to stay tuned for the AMA session to follow, where Dr. Dayspring will answer listeners' questions.  It has been a privilege engaging with Dr. Dayspring throughout this masterclass series. I know you will have learned a lot from it! IN THIS EPISODE YOU WILL LEARN: · The lack of research and consistency in addressing the needs of women in various stages of life · Dr. Dayspring discusses the use of bile acid sequestrants for lowering LDL cholesterol · Dr. Dayspring discusses the history of bile acid sequestrant use, explaining why their use is limited · How bempedoic acid and statins lower LDL cholesterol · Potential contraindications for bempedoic acid · The benefits and risks of using fibrates to reduce heart attacks · Dr. Dayspring explains why fibrates work best for genetic hypertriglyceridemia · Why reducing ApoB is essential for atherosclerosis patients, especially for high-risk patients · Dr. Dayspring explains why small LDL particles are dangerous · The ideal ApoB level for those who have no heart disease and are not diabetic  Bio: Thomas Dayspring MD is a Fellow of both the American College of Physicians and the National Lipid Association and is certified in internal medicine and clinical lipidology. After practicing in New Jersey for 37 years, in 2012, he moved to Virginia to serve as an educational director for a nonprofit cardiovascular foundation until mid-2019 as a Chief Academic Advisor for two major CV laboratories. Since then, he has served as a virtual cardiovascular/lipidology educator. Career-wise, he has given over 4000 domestic (in all 50 states) and several international lectures, including over 600 CME programs on atherothrombosis, lipids/lipoproteins (and their treatment), vascular biology, biomarker testing, and women's cardiovascular issues. He has authored several manuscripts and lipid textbook chapters and performed several podcasts. For several years, he was an Associate Editor of the Journal of Clinical Lipidology. He received the 2011 National Lipid Association's Presidents Award for services to clinical lipidology and the 2023 Foundation of NLA Clinician/Educator Award. He has over 34K followers on his educational Twitter (X) feed (@Drlipid). He has Gold Heart Member status as a professional member of the American Heart Association, and he serves as a Social Media Ambassador for the European Atherosclerosis Society and the National Lipid Association. Connect with Cynthia Thurlow Follow on Twitter Instagram LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Connect with Dr. Thomas Dayspring On Twitter (@DrLipid) On LinkedIn

ไลฟ์ #74: The Cholesterol Wars สรุปหนังสือ และงานวิจัยของ Prof.Daniel Steinberg MD, PhD จำนวน 5 ฉบับ (ตอนที่ 1) หลังจากที่พฤติกรรมของคนทั่วโลกเปลี่ยนเป็นเสพข้อมูลเกือบทุกประเภทผ่านทางโซเชียลมีเดีย การให้ข้อมูลที่ผิดจากการไม่รู้จริง (Misinformation) และ การจงใจบิดเบือนข้อมูล (Disinformation) กลายเป็นอันตรายอันดับที่ 2 ใน 2 ปีข้างหน้า จากรายงานของ World Economic Forum พี่ปุ๋มเคยเขียนโพสต์สรุปรายงานของ WEF ไปแล้วค่ะ อันตรายของการมีระดับ cholesterol และ ldl-cholesterol สูงเกินกว่าระดับทางสรีรวิทยา เป็นหัวข้อที่ดีเบตกันทางโซเชียลมีเดียในเรื่องสุขภาพมากที่สุดเรื่องหนึ่ง มีการให้ข้อมูลที่ผิดพลาดจากการไม่รู้จริงและหรือการจงใจบิดเบือนข้อมูลในโลกโซเชียลมีเดีย ซึ่งก่อให้เกิดความสับสนและทำให้คนบางคนที่มีระดับ ldl-cholesterol สูงลิ่ว ตัดสินใจปฏิเสธการได้รับยาลดไขมันในเลือด ถ้าจะว่าไปการดีเบตนี้ไม่ใช่เพิ่งมี แต่เกิดขึ้นนับย้อนกลับไปได้มากกว่า 50 ปี ในไลฟ์#74 นี้ พี่ปุ๋มจะพาน้องๆไปทำความรู้จัก Prof.Daniel Steinberg MD, PhD นักชีวเคมีและแพทย์ที่ได้รับการเทรนจาก Harvard Medical School ที่เข้าไปเริ่มต้นงานวิจัยที่ National Heart Institute ตั้งแต่เพิ่งเริ่มก่อตั้งในช่วงปี ค.ศ. 1950 เขาบุกเบิกงานวิจัยเรื่อง lipoproteins กับความเกี่ยวพันโรคหัวใจมาตลอดระยะเวลาการทำงาน 64 ปี แรงบันดาลใจมาจากงานวิจัยของ Prof.John Gofman MD, PhD Godfather ของ Clinical Lipidology ซึ่งค้นพบ plasma lipoproteins 3 ประเภท (VLDL, LDL, HDL) ในทศวรรษที่ 1950 ผลงานวิจัยที่ถือว่าเป็นคุณูปการยิ่งใหญ่ต่อวงการ Clinical Lipidology คือการที่ Prof.Daniel และทีมนักวิจัย ค้นพบกระบวนการที่ LDL-particle เมื่อแทรกเข้าไปใต้ชั้นหลอดเลือดและติดกับ proteoglycan แล้ว จะต้องมีขั้นตอนการเกิด LDL-particle modification ซึ่งเกี่ยวข้องกับ lipid peroxidation ก่อนที่ scavenger receptor บน macrophage จะสามารถดูดคอเลสเตอรอลเข้าไปได้ เป็นที่มาของ The LDL Oxidation Hypothesis ในปี 1984 ตลอดอายุขัยของเขา (เสียชีวิตเมื่อปี 2015 อายุ 93 ปี) ทำงานวิจัยตีพิมพ์มากกว่า 400 ฉบับ งานวิจัย 5 ฉบับที่พี่ปุ๋มจะนำมาทะยอยสรุปให้น้องๆได้ฟัง จะทำให้เราสิ้นสงสัยกับข้อมูลผิดๆเกี่ยวกับ cholesterol ที่แพร่กระจายกันอยู่ทางโซเชียลมีเดีย หนังสือ The Cholesterol Wars ที่เขาเขียนในปี 2007 เพื่อที่จะรวบรวมดีเบตเกี่ยวกับความเข้าใจผิดเกี่ยวกับ cholesterol กับความเกี่ยวพันโรคหลอดเลือดหัวใจ References 1. An interpretive history of the cholesterol controversy: part I https://www.jlr.org/article/S0022-2275(20)31274-8/pdf 2. Daniel Steinberg, 1922–2015 https://www.pnas.org/doi/pdf/10.1073/pnas.1512413112?download=true 3. Lipid-Modifying Agents,From Statins to PCSK9 Inhibitors Lipid-Modifying Agents, From Statins to PCSK9 Inhibitors: JACC Focus Seminar - ScienceDirect 4. Low-density lipoproteins cause atherosclerotic cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus statement from the European Atherosclerosis Society Consensus Panel Low-density lipoproteins cause atherosclerotic cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus statement from the European Atherosclerosis Society Consensus Panel | European Heart Journal | Oxford Academic 5. Cholesterol Denialism is Pseudoscience Cholesterol Denialism is Pseudoscience #หาคำตอบสุขภาพจากงานวิจัยไม่ใช่จากเรื่องเล่า #FatOutHealthspans #Fatoutkeyhealthspans

I am excited to share our fourth class in our informative Lipid Masterclass series today, with the esteemed Dr. Thomas Dayspring. Dr. Dayspring is certified in internal medicine and clinical lipidology and is a distinguished fellow of the American College of Physicians and the National Lipid Association. He brings a wealth of expertise to our discussion today. In this class, we dive into lipid and lipoprotein dynamics during the menopausal transition, exploring the impact of estrogen on gut health and its effects on laboratory findings. We look at the differences between hyper absorbers and hyper synthesizers, sharing clinical insights on routine lipid panels that can let you know if you are one of those individuals. We talk about Boston Heart Testing, highlighting the impact of specific biomarkers on brain health lipids and lipoproteins, and we get into the staggering differences between the half-lives of peripheral cholesterol and brain cholesterol. We discuss lipid permeability across the blood-brain barrier, highlighting those at risk for brain health concerns as they age, and we reveal strategies for managing lipid abnormalities. We also focus on LP(a), an ApoB lipoprotein with potent atherogenic and thrombotic properties, and its implications regarding calcific aortic stenosis.  I am sure you will find this enlightening conversation with Dr. Dayspring invaluable. There is one more class yet to come in this masterclass series. Be sure to listen in! IN THIS EPISODE YOU WILL LEARN: How cholesterol absorption in the gut increases in perimenopausal women How hyper cholesterol absorbers tend to have elevated HDL cholesterol The impact of phytosterols on cholesterol absorption When should hyperabsorbers consider treatment? What research has shown regarding the differing effects of estrogen on brain health for older versus younger menopausal women What happens if a statin crosses the blood-brain barrier? How cholesterol synthesis relates to cognitive impairment  The importance of understanding LP-PLA2 test results How Lp(a) levels in women tend to fluctuate, particularly during menopause Should women with heart disease consider hormone replacement therapy?   Bio: Thomas Dayspring MD is a Fellow of the American College of Physicians and the National Lipid Association certified in internal medicine and clinical lipidology. After practicing in New Jersey for 37 years, in 2012, he moved to Virginia to serve as an educational director for a nonprofit cardiovascular foundation until mid-2019 as a Chief Academic Advisor for two major CV laboratories. Since then, he has served as a virtual cardiovascular / lipidology educator. Career-wise, he has given over 4000 domestic (in all 50 states) and several international lectures, including over 600 CME programs on atherothrombosis, lipids/lipoproteins (and their treatment), vascular biology, biomarker testing, and women's cardiovascular issues. He has authored several manuscripts and lipid textbook chapters and performed several podcasts. For several years, he was an Associate Editor of the Journal of Clinical Lipidology. He received the 2011 National Lipid Association's Presidents Award for services to clinical lipidology and the 2023 Foundation of NLA Clinician/Educator Award. He has over 34K followers on his educational Twitter (X) feed (@Drlipid). He has Gold Heart Member status as a professional member of the American Heart Association, and he serves as a Social Media Ambassador for the European Atherosclerosis Society and the National Lipid Association. Connect with Cynthia Thurlow Follow on Twitter Instagram LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Connect with Dr. Thomas Dayspring On Twitter (@DrLipid) On LinkedIn

Dr. Thomas Dayspring joins me again today for the third class in our Lipid Masterclass Series. Dr. Dayspring brings a wealth of expertise as a certified specialist in internal medicine and clinical lipidology, holding fellowships with the American College of Physicians and the National Lipid Association. This hour-long class is devoted to women's health and abnormal lipids. We continue with our conversation about ApoB, discussing ways to look at other lipid abnormalities related to abnormal ApoBs and talking about our ideal lab values and lifestyle modifications, briefly touching on my lipid journey and the medication I have been taking for the past six months. We examine diagnostics and their limitations, getting into CACs, coronary artery calcification scoring, CIMT, the labs we need to look at, the role of Lp(a), and how it affects our heart. We look into the changes women experience from losing estrogen in menopause, clues women can use to predict future cardiovascular risk, how estrogen helps clear LDL from the body, and the changes occurring with menopause, including higher ApoBs. We also dive into risks women face for cardiovascular disease, the impact of the Women's Health Initiative study, and absorption and synthesis challenges with cholesterol. Stay tuned for more! IN THIS EPISODE YOU WILL LEARN: Why ApoB testing for inherited lipoprotein disorders is essential  Why hypo beta lipoproteins (HDL) are critical for maintaining good health The benefits of a holistic approach to treating high cholesterol The three stages of prevention for atherosclerosis How Lp(a) impacts heart health The importance of assessing early heart function through Lp(a) testing How your pregnancy history can help in predicting your risk for cardiovascular disease Why should women be more concerned about cardiovascular disease than breast cancer? How the Women's Health Initiative led gynecologists to be more cautious about prescribing HRT How genetically mediated cholesterol abnormalities can impact our ability to absorb and synthesize cholesterol   Bio: Thomas Dayspring MD is a Fellow of both the American College of Physicians and the National Lipid Association and is certified in internal medicine and clinical lipidology. After practicing in New Jersey for 37 years, in 2012, he moved to Virginia to serve as an educational director for a nonprofit cardiovascular foundation until mid-2019 as a Chief Academic Advisor for two major CV laboratories. Since then, he has served as a virtual cardiovascular / lipidology educator. Career-wise he has given over 4000 domestic (in all 50 states) and several international lectures, including over 600 CME programs on atherothrombosis, lipids/lipoproteins (and their treatment), vascular biology, biomarker testing, and women's cardiovascular issues. He has authored several manuscripts and lipid textbook chapters and performed several podcasts. For several years, he was an Associate Editor of the Journal of Clinical Lipidology. He was the recipient of the 2011 National Lipid Association's Presidents Award for services to clinical lipidology and the 2023 Foundation of NLA Clinician/Educator Award. He has over 34K followers on his educational Twitter (X) feed (@Drlipid). He has Gold Heart Member status as a professional member of the American Heart Association, and he serves as a Social Media Ambassador for the European Atherosclerosis Society and the National Lipid Association. Connect with Cynthia Thurlow Follow on Twitter Instagram LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Connect with Dr. Thomas Dayspring On Twitter (@DrLipid) LinkedIn

Folge ansehen oder anhören auf YouTube I Apple Podcasts I SpotifyDanke an die WerbepartnerEss-Wissen Club für PraktikerDein Schlüssel zu aktuellem Ernährungswissen und Vorlagen für die Praxis14 Tage ohne Risiko testen. Rabatt-Code PODCAST10 und du bekommst 10% auf die Jahresmitgliedschaft.https://esswissen-club.com/Kapitel00:00 Darum geht es in der Folge 01:42 EsssWissen Club für Praktiker Vorstellung 03:04 Begrüßung und EInleitung ins Thema 06:53 Cholesterin und LDL-Cholesterin 11:07 Lean Mass Hyperresponders - Besprechung der speziellen Subgruppe von Personen, die auf kohlenhydratarme oder ketogene Ernährung mit einem erhöhten LDL-Cholesterin reagieren. 17:25 Keine Korrelation zwischen LDL und gesättigten Fetten 17:53 Lipid Energy Model 22:58 Experiment Oreos vs. Statine 28:55 Diskussion der Klinischen Konsequenz Wir sprechen überWir hinterfragen die gängigen Annahmen über LDL-Cholesterin und dessen Rolle bei Herz-Kreislauf-Erkrankungen und beleuchten, wie individuelle Reaktionen auf eine kohlenhydratarme Ernährung das LDL-Cholesterin beeinflussen können. Insbesondere diskutieren wir das Phänomen der sogenannten Lean Mass Hyperresponder, Personen, die bei ketogener Ernährung einen außergewöhnlichen Anstieg des LDL-Cholesterins erleben, und stellen die Frage nach der klinischen Relevanz dieser Veränderungen. Durch die Analyse von Studien und persönlichen Experimenten, wie dem Vergleich der LDL-Cholesterin-Senkung durch Statine versus die Aufnahme von Oreo-Keksen, hinterfragen wir kritisch die traditionelle Fokussierung auf LDL-Cholesterin als primären Risikofaktor. Die drei wichtigsten Takeaways, die du aus dieser Episode mitnehmen wirst, sind:Die komplexe Beziehung zwischen Cholesterin, LDL und Ernährung: Wir entmystifizieren, wie Cholesterin und LDL tatsächlich funktionieren und warum eine pauschale Bewertung und die Einteilung in gutes und böses Cholesterin zu kurz greift.Die spezielle Gruppe der Lean Mass Hyperresponders: Erfahre, warum bestimmte Personen auf eine ketogene Ernährung mit einem unerwartet hohen Anstieg des LDL-Cholesterins reagieren und was das bedeutet.Praktische Ansätze und was die Wissenschaft sagt: Wir teilen die neuesten Erkenntnisse und Studien, die Licht auf diese oft missverstandenen Themen werfen und wir zeigen dir, wie du diese Informationen für deine Gesundheitsziele nutzen kannst.Alles über Ulrike Gonder und Julia TulipanÜber Ulrike Gonder: Dipl. oec. troph. und Freie Wissenschaftsjournalistin https://ulrikegonder.de/ Über Julia Tulipan: Magister der Biologie und Master klinische Ernährungsmedizin https://juliatulipan.com/Relevante ArtikelNorwitz, Nicholas G., et al. "The lipid energy model: reimagining lipoprotein function in the context of carbohydrate-restricted diets." Metabolites 12.5 (2022): 460. https://www.mdpi.com/2218-1989/12/5/460Norwitz, Nicholas G., et al. "Elevated LDL-cholesterol levels among lean mass hyper-responders on low-carbohydrate ketogenic diets deserve urgent clinical attention and further research." Journal of Clinical Lipidology 16.6 (2022): 765-768. https://www.lipidjournal.com/article/S1933-2874(22)00295-1/fulltextYi, Sang-Wook, Jee-Jeon Yi, and Heechoul Ohrr. "Total cholesterol and all-cause mortality by sex and age: a prospective cohort study among 12.8 million adults." Scientific reports 9.1 (2019): 1596.https://www.nature.com/articles/s41598-018-38461-yCholesterol and all-cause mortality in elderly people from the Honolulu Heart Program: a cohort studySchatz, Irwin J., et al. "Cholesterol and all-cause mortality in elderly people from the Honolulu Heart Program: a cohort study." The lancet 358.9279 (2001): 351-355.https://www.readcube.com/library/0ba8445e-192b-440f-8d84-60732183d7ec:9996a2ae-9692-47f3-a3c1-36d4b240516cRavnskov, Uffe, et al. "Lack of an association or an inverse association between low-density-lipoprotein cholesterol and mortality in the elderly: a systematic review." BMJ open 6.6 (2016): e010401.https://bmjopen.bmj.com/content/6/6/e010401Rong, Shuang, et al. "Association of Low‐Density Lipoprotein Cholesterol Levels with More than 20‐Year Risk of Cardiovascular and All‐Cause Mortality in the General Population." Journal of the American Heart Association 11.15 (2022): e023690.https://www.readcube.com/library/0ba8445e-192b-440f-8d84-60732183d7ec:8e3bee53-f8e6-44b8-93c9-cb3e86dee086Bevor wir beginnen, möchte ich mich bei meinen Sponsoren bedanken, deren Unterstützung es mir ermöglicht, regelmäßig spannende Inhalte für dich zu erarbeiten.Danke an die Werbepartner, ohne deren Unterstützung dieser Podcast nicht möglich wäre.Ess-Wissen Club für PraktikerDein Schlüssel zu aktuellem Ernährungswissen und Vorlagen für die PraxisBleibst Du gerne auf dem Laufenden, ohne in Studienbergen zu versinken? Der EWiP-Club ist Deine Lösung! Wir filtern, übersetzen und kondensieren die neuesten Ernährungserkenntnisse direkt auf Deinen Schreibtisch - in deutscher Sprache und praxisnah aufbereitet.14 Tage ohne Risiko testen. Rabatt-Code PODCAST10 und du bekommst 10% auf die Jahresmitgliedschaft. https://esswissen-club.com/ Bitte beachten Sie auch immer den aktuellen "Haftungsausschluss (Disclaimer) und allgemeiner Hinweis zu medizinischen Themen" auf https://juliatulipan.com/haftungsausschluss/

ไลฟ์#72 : สรุปเล็คเชอร์ The Evolving Narrative of HDL-C หลังจากความล้มเหลวของงานวิจัยยา CSL112 ของบริษัท biotech CSL Behring ซึ่งเป็น Human Apolipoprotein A1 (apolipoprotein สำคัญบน HDL Particle) CSL112 ทำหน้าที่ผลักคอเลสเตอรอลออกจาก macrophage ของ plaque หลอดเลือด (Cholesterol Efflux Enhancer) และส่งเสริมเอ็นไซม์ LCAT ซึ่งหน้าที่สำคัญนี้ของ ApolipoproteinA1 บนผนัง HDL เป็นหน้าที่ที่นักวิจัยให้ความสนใจเป็นอย่างมาก และเป็นความหวังสำคัญในการสร้างกลยุทธ์เพื่อลดความเสี่ยง/รักษาโรคหลอดเลือดหัวใจอุดตันให้ดียิ่งขึ้น งานวิจัยสำคัญที่ล้มเหลวนี้ทำให้ความเข้าใจบทบาทของ HDL เหมือนกลับไปตั้งต้นใหม่ เพราะงานวิจัยสารพัดในอดีตที่ทดสอบการเพิ่มปริมาณคอเลสเตอรอลที่อยู่ใน HDL และทดสอบหน้าที่ของ HDL (functionality of HDL) ต่อการลดความเสี่ยงของโรคหลอดเลือดหัวใจดูเหมือนจะล้มเหลวไปหมด ไม่ว่าจะเป็น Niacin, Fibrate, Gemfibrozil, Hormone Replacement และ CETP inhibitors พี่ปุ๋มโชคดีที่ได้มีโอกาสฟังเล็กเชอร์เรื่อง The Evolving Narrative of HDL-C: Contemporary Insights on Quality vs Quantity for Targeting Cardio Protection เมื่อวันที่ 2 มิ.ย. 2566 จัดโดย National Lipid Association เป็นเล็คเชอร์ที่ดีมาก (กอไก่ล้านตัว) โดยศาสตราจารย์ผู้ทรงคุณวุฒิในด้านโรคหลอดเลือดหัวใจและ Lipidology 3 ท่าน หัวข้อเป็นดังนี้ค่ะ 1. Rethink the HDL Hypothesis: Then and Now โดย Professor Vera A. Bittner MD, MNLA University of Alabama 2. More than a Number: Functional Role of HDL for Atheroprotection โดย Professor Robert S. Rosenson MD, FNLA, Mount Sinai New York 3. Restoring confidence in HDL: Does CEC hold a promising as a potential therapeutic target? โดย Professor Christie M. Ballantyne MD, Baylor College of Medicine, Houston Texas (คนนี้เป็น Editor texbook สำคัญ Clinical Lipidology) แม้เนื้อหามันจะยาก แต่มันก็ท้าทายพี่ในการจะนำมาสรุปเป็นไลฟ์ #72 โพสต์นี้ไฮไลท์ประเด็นสำคัญจากเล็คเชอร์ HDL ที่พี่ได้ฟัง ให้อ่านเป็นน้ำจิ้มกันก่อน 1. HDL Nomenclature: HDL =/= HDL-C แต่เกี่ยวข้องกับขนาดของ particle ความหนาแน่น รูปร่าง ประจุ จำนวน ที่สำคัญมากคือ ประเภทของ Apolipoprotein (AI, AII, CIII, E) โปรตีน มากกว่า 300 ชนิด ไขมัน มากกว่า 300 ชนิด micro RNA ที่อยู่บน HDL Particle ส่งผลต่อหน้าที่ของ HDL ที่แตกต่างกันในคนแต่ละคน (wow!!) 2. ดังนั้น ความเชื่อฝังหัวที่มาจาก Classic Epidemiological Study อย่าง Framingham Study ว่า HDL เป็น good cholesterol การมีระดับ HDL-Cholesterol ที่สูง จะลดความเสี่ยงของโรคหลอดเลือดหัวใจนั้น เราควรจะลืมมันไปได้แล้ว 3. Low HDL-C predicts poor outcomes, high HDL-C is not protective for ASCVD (Atherosclerotic Cardiovascular Disease) 4. เราควรจะมุ่งความสนใจไปที่หน้าที่ของ proteins และ Lipid ที่อยู่บน HDL ซึ่งส่งผลให้ทำหน้าที่แตกต่างกัน ไม่ใช่สนใจปริมาณคอเลสเตอรอลที่อยู่ใน HDL พี่หวังว่าไลฟ์นี้ จะทำให้น้องๆที่มีความเชื่อว่า ไม่ต้องสนใจระดับ LDL-Cholesterol ที่สูง ตราบใดที่ระดับไตรกลีเซอไรด์ต่ำ และระดับ HDL-Cholesterol สูง เพราะ LDL particle จะมีขนาดใหญ่ ไม่เป็นอันตรายต่อหลอดเลือดหัวใจ และ HDL-C ที่สูงจะช่วยปกป้องหัวใจ จะได้เข้าใจเสียใหม่ว่า HDL-C ที่สูงไม่ได้มีฤทธิ์ในการปกป้องหัวใจแต่อย่างใด และ LDL particle size ก็ไม่ได้สำคัญมากไปกว่าจำนวน LDL particle #หาคำตอบสุขภาพจากงานวิจัยไม่ใช่จากเรื่องเล่า#FatOutHealthspans#ApoBgirl

Today, I am excited to share the first class in a series of lipid masterclasses with the amazing Dr. Thomas Dayspring! Dr. Dayspring is certified in internal medicine and clinical epidemiology and is a fellow of the American College of Physicians and the National Lipid Association. He was previously the Educational Director of a nonprofit organization and has served as the Chief Academic Advisor for two major cardiovascular labs.  Due to the in-depth nature of my discussions with Dr. Dayspring over several sessions, each lasting nearly six hours, it seemed logical to present these masterclasses in segmented chunks to make them easier to understand. In our first class today, we dive into the fundamentals, exploring what lipids are and how lipids and fatty acids are classified. We cover the physiology and transportation of cholesterol and the role of apoptosis, apo-proteins, and apo-lipoproteins, unravel the differences between HDL, LDL, IDL, and VLDL, and explain how to calculate LDLs and triglycerides for assessing metabolic health. Dr. Dayspring also shares his preferences regarding lab values and the indicators that provide information to help him determine the early risk of cardiovascular disease. We get into some detailed aspects of physical chemistry in this episode, so I highlight the main clinical points throughout our conversation to make it more understandable. Be sure to join Dr. Dayspring and me for our next episode in the lipid masterclass series. IN THIS EPISODE YOU WILL LEARN: What are lipids, and why are they important? Dr. Dayspring explains what triglycerides are. How lipids get absorbed and transported throughout the body What lipoproteins are, and how they get classified How cholesterols get calculated The impact of triglycerides on cholesterol levels and cardiovascular health How high triglyceride levels can indicate early insulin resistance or increased ASCVD risk What is the role of HDL particles? How metabolic syndrome impacts cardiovascular health Bio: Thomas Dayspring MD is a Fellow of both the American College of Physicians and the National Lipid Association and is certified in internal medicine and clinical lipidology. After practicing in New Jersey for 37 years, in 2012, he moved to Virginia. He served as an educational director for a nonprofit cardiovascular foundation and until mid-2019 as a Chief Academic Advisor for two major CV laboratories. Since then, he has served as a virtual cardiovascular / lipidology educator. Career-wise he has given over 4000 domestic (in all 50 states) and several international lectures, including over 600 CME programs on atherothrombosis, lipids/lipoproteins (and their treatment), vascular biology, biomarker testing, and women's cardiovascular issues. He has authored several manuscripts and lipid textbook chapters and performed several podcasts. For several years he was an Associate Editor of the Journal of Clinical Lipidology. He was the recipient of the 2011 National Lipid Association's Presidents Award for services to clinical lipidology and the 2023 Foundation of NLA Clinician/Educator Award. He has over 34K followers on his educational Twitter (X) feed (@Drlipid). He has Gold Heart Member status as a professional member of the American Heart Association and serves as a Social Media Ambassador for the European Atherosclerosis Society and the National Lipid Association. Connect with Cynthia Thurlow Follow on Twitter, Instagram & LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Connect with Dr. Thomas Dayspring Twitter (@DrLipid) LinkedIn Books written by Gary Taubes

Thank you for joining us for another episode of the Low Carb MD Podcast. Dr. William Cromwell is board-certified in Family Medicine and Clinical Lipidology with over 20 years of clinical research experience. Dr. Cromwell received his MD from Louisiana State University and completed his residency at the Trover Clinic Foundation in Madisonville, KY in 1990. Since completing residency, he has held numerous concurrent roles, practicing medicine, teaching at various universities, and serving as Medical Director, Chief Medical Officer, and Principal Investigator at organizations nationwide. Dr. Nick Norwitz completed his PhD at Oxford and is currently working on his MD at Harvard with the aim of becoming a physician scientist. His career goal is to help change the medical system to a patient-collaborative and metabolic-medicine first system. In this episode, Drs. Tro, William, and Nick talk about a recent meta analysis on the relationship between saturated fat intake, BMI, and LDL on a low carb diet, an overview on the history of knowledge about saturated fat and cholesterol, and Statins versus Oreos. For more information, please see the links below. Thank you for listening!   Links:   Dr. William Cromwell: Twitter Precision Health Reports   Dr. Nick Norwitz: Twitter YouTube Video Abstract Oreo Cookie Treatment Paper (**CALL TO ACTION** to Tweet the paper with the link in the tweet within the first 280 characters. Helps Altmetrics)   Dr. Brian Lenzkes:  Website Twitter   Dr. Tro Kalayjian:  Website Twitter Instagram   Doctor Tro App Join a growing community of individuals who are improving their metabolic health; together.  Get started at your own pace with a self-guided curriculum developed by Dr. Tro and his care team, community chat, weekly meetings, courses, challenges, message boards and more.    Apple  Google  Learn more  

References Journal of Clinical Lipidology. 2022. Volume 16, Issue 4, July–August. Pages 472-482. Guerra. 2023. -Lecture notes JLR. 2012. Volume 53, Issue 9, September. Pages 1783-1799 Mozart, WA. 1782 Serenade No12 C.Minor. K388/384a https://youtu.be/xOaP9G-9wi8?si=CE8d9hcuUfbaqa4z --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

‘Perimenopause and Heart Health' is the focus of today's episode on the Perimenopause WTF! podcast. Listen to Dr. Jayne Morgan & Dr. Nicole Harkin talk about everything heart disease related, from increased blood pressure, to sleep disturbances, to hot flashes. They talk about the controversies and cutting edge research happening today, so tune in as these two powerhouse MD's advocate for deeper cardiac evaluations for women, they underscore the need for a more nuanced approach in addressing menopausal health concerns, suggesting that cardiologists take a more central role in managing menopausal heart risks.  Did you want to read the conversation instead? Now you can! We never hold back so neither should you! Send in a voice message question:  Perimenopause WTF! brought to you by perry!  perry is a safe space for connections, support, new friendships and occasional laughs during the menopause transition. It's a #1 perimenopause app where you will meet other warriors who understand.  Sharing experiences will help to feel ‘normal' again. No, you're not crazy and no, you are not alone. With our network of wonderful menopause experts, we have gathered an abundance of  evidence-based knowledge, articles, podcasts and a new book: The Perry Menopause Journal. To learn more visit: www.heyperry.com https://perry.app.link/perimenopausewtf The Perimenopause Journal Are you looking for a meaningful way to prioritize your well-being during this crucial phase of your life? Do you crave self-care practices tailored specifically to the ups and downs of perimenopause? The journal offers: 1️⃣ Thoughtful Prompts: 2️⃣ Progress tracking: 3️⃣ Evidence-based knowledge  4️⃣ Community Support To grab a journal visit:  heyperry.com/theperrymenopausejournal or amzn.to/3Nt1YYR

Dr. Michael Lenz is Board Certified in Pediatrics and Internal Medicine, meaning he sees patients from newborns through adulthood. He is practicing and will continue to practice in Southeastern Wisconsin in the metro Milwaukee area. This lifetime of experience is especially important in working with those who have fibromyalgia, as these and related conditions often start in childhood but are not recognized until years or even decades later. He is also a diplomat of the Board of Lifestyle Medicine and a diplomat of the Board of Clinical Lipidology. His goal is to weave the best of lifestyle medicine with medical management to help patients their loved ones, and their doctors learn more about these conditions and live the best life possible. Dr. Lenz graduated from the Medical College of Wisconsin in Milwaukee and completed his Residency at the Virginia Commonwealth University Hospitals in Richmond, Virginia. Dr. Lenz has helped hundreds of patients suffering from fibromyalgia and related problems in children and adults. He is committed to educating, inspiring, and equipping patients to walk through this battle triumphantly. He recently transitioned to the  Medical College of Wisconsin and Froedert. _______________________________________________________ Fibromyalgia Impact Questionnaire (FIQ) https://www.rheumatology.org/I-Am-A/Rheumatologist/Research/Clinician-Researchers/Fibromyalgia-Impact-Questionnaire-FIQ Doctor | Conquering Your Fibromyalgia | United States https://www.conqueringyourfibromyalgia.com/ Dr. Michael Lenz //DoctorMichaelLenz@gmail.com _______________________________________________________ Become a JOWMA Member! www.jowma.org  Follow us on Instagram! www.instagram.com/JOWMA_org  Follow us on Twitter! www.twitter.com/JOWMA_med  Follow us on Facebook! https://www.facebook.com/JOWMAorg/ Stay up-to-date with JOWMA news! Sign up for the JOWMA newsletter! https://jowma.us6.list-manage.com/subscribe?u=9b4e9beb287874f9dc7f80289&id=ea3ef44644&mc_cid=dfb442d2a7&mc_eid=e9eee6e41e

Did you know that heart disease is the leading cause of death globally? But the good news is that most cases of heart disease can be prevented by adopting healthy habits and making lifestyle changes. WATCH THE FULL YOUTUBE VERSION HERE: https://youtu.be/GdYso8Iln7Q  In this episode, join me as I sit down with Dr. Nicole Harkin, a preventive cardiologist who is board certified in Internal Medicine, Cardiology, Echocardiography, Nuclear Cardiology, and Clinical Lipidology. She is the founder of Whole Heart Cardiology, a preventive telecardiology practice that provides cardiac optimization through precision and lifestyle medicine for patients in California, New York, and Florida. She is also the Chief Medical Advisor for PlateUp, a health tech start-up dedicated to improving health through nutrition, and is a member of Planted Forward, a comprehensive, multi-specialty telemedicine health team. She proudly serves on several committees, including the American Society for Preventive Cardiology Nutrition Working Group and the American College of Cardiology California Chapter Prevention Committee. She currently lives with her family in San Francisco, CA. When not doctoring, she spends the majority of her time with her three young children. She also enjoys cooking, yoga, Peloton-ing, hiking, and traveling Plus, you'll learn about the major risk factors of heart disease, the warning signs, and what you can do to reduce your risk. Whether you are young or old, it's never too early or too late to start taking care of your heart.

Dr. Laura welcomes her first guest of 2023, author and Chief Medical Director of Employee Health and Wellbeing at Johns Hopkins Medicine, Dr. Richard Safeer to the show. Dr. Safeer just released his first book, “A Cure for the Common Company” and he talks about his book and the benefits of workplace wellbeing with Dr. Laura. Richard Safeer wrote his book because he sees that what companies are doing may not be as effective as they thought. He believes there is a better way to use company time, energy, and resources to effect a greater culture of wellbeing. He explains the six building blocks of wellbeing, where the title of his book came from, and how employers are instrumental in the health of their employees in this inspiring conversation with Dr. Laura.“So, you know, one of the most common challenges I see workplaces have is that the employer takes this individual approach. Here are the resources, go ahead and use them and get better. As opposed to recognizing that we're all in this together, that our well being is a team sport and that we rely on each other to improve and maintain our health and well-being” - Richard SafeerAbout Dr. Richard Safeer:Dr. Safeer is Chief Medical Director of Employee Health and Wellbeing at Johns Hopkins Medicine. Dr. Safeer completed his B.S. in Nutrition at Cornell University before graduating from medical school at the S.U.N.Y. at Buffalo (magna cum laude). He completed his residency in Family Medicine and a Faculty Development Fellowship. He is certified in Clinical Lipidology. He's a fellow of the American Academy of Family Practice, the American College of Lifestyle Medicine, and the American College of Preventive Medicine.Prior to Hopkins, Dr. Safeer practiced family medicine in Virginia. He was then on faculty at the George Washington University, the Residency Director of Family Medicine in his last year. He was the Medical Director of an Occupational Health Center in Baltimore and Wellness Director for the Mid-Atlantic region of the parent company, just before starting at CareFirst BlueCross BlueShield as the Medical Director of Preventive Medicine. He has been credited by some for bringing ‘wellness' to the realm of the managed care industry. He also led CareFirst BCBS to be among the first cohort of health plans to be accredited for Wellness by NCQA. He holds an adjunct faculty appointment at the American University, where he taught “Organizational Health”.Amongst his responsibilities at Hopkins, includes leading the employee health and well-being initiative, Healthy at Hopkins. Dr. Safeer also advises the institution on matters related to health plan benefits, occupational health, and the employee assistance program. He has published many journal articles and his work is featured in many books. He regularly speaks to national audiences on the employee health and wellbeing space, more specifically on how to create healthy workplace cultures. He previously served on the board of the American College of Lifestyle Medicine, a professional organization he helped establish. In January 2023, Wiley will release his book, “A Cure for the Common Company”.Dr. Safeer enjoys most outdoor activities including biking and tennis.  He's hiked in the Andes, Alaska, and Australia as well in many national parks.  He lives in Columbia Maryland with his wife, three kids and their dog Kami.  Watch for his book, “A Cure for the Common Company”, coming in January 2023. Resources:Richard Safeer, MDRichard Safeer on LinkedIn“A Cure for the Common Company: A Well-Being Prescription for a Happier, Healthier, and More Resilient Workforce” by Richard Safeer, MD“Leading with Gratitude” by Adrian Gostick and Chester Elton“Anxiety at Work” by Adrian Gostick and Chester Elton“Drive” by Daniel H. PinkLearn more about Dr. Laura on her website: https://drlaura.liveFor more resources, look into Dr. Laura's organizations: Canada Career CounsellingCalgary Career CounsellingSynthesis Psychology

Dr. Harold Bays is a giant in the field of obesity medicine, endocrinology, and cardiometabolic health. Luckily for us working in these fields, he chose medicine over stand-up comedy when he reached a critical fork in the road. Karli and Dr. Bays discuss the evolution of obesity medicine and obesity pharmacotherapy, the importance of body composition analysis, the limitations of BMI, and where the field of obesity medicine is headed. Dr. Harold Bays is the Medical Director and president of the Louisville Metabolic and Atherosclerosis Research Center and has served as an investigator for over 500 clinical trials. Dr. Bays is Board Certified in Internal Medicine and Endocrinology. He is a Diplomate of the American Board of Obesity Medicine, and a Diplomate of the American Board of Clinical Lipidology.Dr. Bays is also the editor in chief of the Obesity Medicine Association's Medical journal: Obesity Pillars, and has been heavily involved with the Obesity Algorithm since 2013. He is also the Chief Science Officer and co-host of the Obesity, a disease Podcast for OMA.In 2005, Dr. Bays was the first to describe and publish how “sick fat” (adiposopathy) contributes to metabolic disease, and among his awards include the 2015 National Lipid Association “President's Service Award” and the 2016 Obesity Medicine Association “Obesity Medicine Clinician of the Year.”Click HERE to go to the free, open access journal, Obesity Pillars, the official joyrnal of the Obesity Medicine AssociationSupport the showThe Gaining Health Podcast will release a new episode monthly, every second Wednesday of the month. Episodes including interviews with obesity experts as well as scientific updates and new guidelines for the management of obesity.If you're a clinician or organization looking to start or optimize an obesity management program, and you want additional support and resources, check out the Gaining Health website! We offer monthly and annual Memberships, which include live group coaching, a community forum to ask questions and post resources, pre-recorded Master Classes, digital resources inlcuding patient education materials and office forms, and much more! We also sell our popular Gaining Health products, including a book on developing an obesity management program, editable forms and templates, and patient education materials in our Gaining Health Shop! If you are loving this podcast, please consider supporting us on Patreon

Dr. Danielle Belardo and her expert guest, world-renowned lipidologist, Dr. Thomas Dayspring, are back for part two of their masterclass in cholesterol and lipids. On today's episode, Danielle and Thomas cover all the nitty-gritty details about the different FDA-approved cholesterol-lowering medications while also busting myths and misconceptions about statins. They also pay some attention to the forgotten step sister of lipidology—high triglycerides. If you are looking to support your cardiovascular health, this episode will leave you with an arsenal of tools to keep your cholesterol in check.       Dr. Belardo and Dr. Dayspring discuss:        Why statins are first line therapy, how they lower LDL cholesterol and the powerful data we have for them    The differences between the various types of statins    How Zetia (ezetimibe) is used to lower cholesterol levels in the blood and when it is indicated for use    The different types of PCSK9 inhibitors, how they work, and how much they lower LDLC   Who has demonstrated mortality benefits from PCSK9 inhibitors and why they aren't the first line of therapy instead of statins   ideal triglyceride ranges and medications available to lower them      Dr. Thomas Dayspring is a world-renowned expert on atherothrombosis, lipoprotein, vascular biology, and advanced lipoprotein testing. With an extensive background of over 37 years in medicine as a clinical lipidologist, Dr. Dayspring has dedicated his career to cardiovascular health. In addition to 17 years of devoted consulting for patients with the most complex lipid disorders in the country, he has served as the Chief Scientific Officer at two of the largest cardiovascular labs for more than 7 years. He is also an official board member of both the American Board of Internal Medicine and the American Board of Clinical Lipidology. Dr. Dayspring has given over 4000 lectures in all 50 states and is considered one of the most requested speakers in the U.S.      Thank you so much for taking the time to contribute to a generation that values fact over fiction! Be sure to rate, review, and follow on your favorite podcast app and let us know which not-so-wellness trend you'd like to hear debunked. Follow your host on Instagram @daniellebelardomd and the podcast @wellnessfactvsfiction. All studies discussed can be found @wellnessfvfjournalclub. Follow Dr. Dayspring @Drlipid.      Thank you to our sponsors for making this episode possible. Check out these deals just for you:  COZY EARTH - Go to cozyearth.com and enter WELLNESS at checkout to SAVE thirty-five  Percent.  ZOCDOC - Go to zocdoc.com/wellness and download the Zocdoc app for FREE. Then start your  search for a top-rated doctor today.    Learn more about your ad choices. Visit megaphone.fm/adchoices

Join Dr. Danielle Belardo and her expert of the week for a special two-part episode with world renowned lipidologist, Dr. Thomas Dayspring, better known on his infamous twitter account as @Drlipid. On today's episode, he dives headfirst into the world of lipidology, providing listeners with a detailed overview of all things cardiovascular health. Danielle and Thomas get right into the cardiovascular myths and misinformation out there, like the dangerous glamorization of certain diets and all natural supplements. So much necessary and educational ground to cover, so make sure to tune in for part 2 next week.    Dr. Belardo and Dr. Dayspring discuss:      What is considered normal vs. abnormal lipoprotein levels   The main differences between primary and secondary prevention of cardiovascular disease    The misinformation surrounding ApoB proteins and atherosclerosis   Why the keto diet is a threat to cardiovascular health    Benefits of guideline-directed medical therapy    Dr. Thomas' concerns with plant-based supplements for cholesterol treatment   The powerful history of statins and why Dr. Belardo and Dr. Dayspring stand behind them as a treatment for cardiovascular disease      Dr. Thomas Dayspring is a world-renowned expert on atherothrombosis, lipoprotein, vascular biology, and advanced lipoprotein testing. With an extensive background of over 37 years in medicine as a clinical lipidologist, Dr. Dayspring has dedicated his career to cardiovascular health. In addition to 17 years of devoted consulting for patients with the most complex lipid disorders in the country, he has served as the Chief Scientific Officer at two of the largest cardiovascular labs for more than 7 years. He is also an official board member of both the American Board of Internal Medicine and the American Board of Clinical Lipidology. Dr. Dayspring has given over 4000 lectures in all 50 states and is considered one of the most requested speakers in the U.S.      Thank you so much for taking the time to contribute to a generation that values fact over fiction! Be sure to rate, review, and follow on your favorite podcast app and let us know which not-so-wellness trend you'd like to hear debunked. Follow your host on Instagram @daniellebelardomd and the podcast @wellnessfactvsfiction. All studies discussed can be found @wellnessfvfjournalclub. Follow Dr. Dayspring @Drlipid.        Thank you to our sponsors for making this episode possible. Check out these deals just for you:  COZY EARTH - Go to cozyearth.com and enter WELLNESS at checkout to SAVE thirty-five  Percent.  Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode of me&my health up we speak with Dr. Michael Lenz who has a strong interest in helping those with Fibromyalgia go beyond just learning to live with but to reducing and even reversing the levels of Fibromyalgia. Weaving the best of lifestyle medicine and medical management.About Dr. Michael LenzDr. Michael Lenz is a practicing physician in Delafield, Waukesha County, Wisconsin. He is Board Certified in Pediatrics and Internal Medicine which means he sees patients from newborns through adulthood. He is also a diplomat of the Board of Lifestyle Medicine and a diplomat of the Board of Clinical Lipidology. Dr. Lenz also has received a T. Colin Campbell Plant-Based Nutrition Certificate. Dr. Lenz graduated from the Medical College of Wisconsin in Milwaukee and completed his Residency at the Virginia Commonwealth University Hospitals in Richmond, Virginia. Dr. Lenz has helped hundreds of patients suffering from fibromyalgia-like pain. He is committed to educating, inspiring, and equipping patients to walk through this battle triumphantly. He is the author and host of the book and podcast, Conquering Your Fibromyalgia.About me&my Health Up & Hostme&my Health Up seeks to enhance and enlighten the wellbeing of others. Host Anthony Hartcher is the CEO of me&my wellness which provides holistic health solutions using food is medicine, combined with a holistic, balanced, lifestyle approach. Anthony holds three bachelor's degrees in Complementary Medicine; Nutrition and Dietetic Medicine; and Chemical Engineering.CreditsPodcast editing: WE EDIT PODCASTSSupport the show

The landmark Reduction of Cardiovascular Events with Icosapent Ethyl–Intervention Trial (REDUCE-IT®) was a global outcomes study designed to assess the cardioprotective efficacy and safety of VASCEPA® (icosapent ethyl) as an add-on to statin therapy in reducing major cardiovascular (CV) events in a high-risk patient population. Join endocrine experts Eliot A. Brinton, MD, FAHA, FNLA, FACE, President of Utah Lipid Center, and Past President, of the American Board of Clinical Lipidology, and Betul Hatipoglu MD, Professor of Medicine at CWRU School of Medicine, and Medical Director for Diabetes & Obesity Center at University Hospital Cleveland Medical Center, to learn about the results of the REDUCE-IT® trial and new developments in CV prevention.

Having a high level of triglycerides in your blood can increase your risk of heart disease. Join endocrine experts Eliot A. Brinton, MD, FAHA, FNLA, FACE, President of Utah Lipid Center, and Past President, of the American Board of Clinical Lipidology, and Betul Hatipoglu MD, Professor of Medicine at CWRU School of Medicine, and Medical Director for Diabetes & Obesity Center at University Hospital Cleveland Medical Center, as they discuss the clinical management of Hypertriglyceridemia (HTG) for cardiovascular disease prevention.

CardioNerds Tommy Das (Program Director of the CardioNerds Academy and cardiology fellow at Cleveland Clinic), Rick Ferraro (cardiology fellow at the Johns Hopkins Hospital), and Dr. Aliza Hussain (cardiology fellow at Baylor College Medicine) take a deep dive on the REDUCE-IT trial with Dr. Peter Toth, director of preventive cardiology at the CGH medical center in Sterling, Illinois, clinical professor in family and community medicine at the University of Illinois School of Medicine, and past president of the National Lipid Association and the American Board of Clinical Lipidology.  Special introduction to CardioNerds Clinical Trialist Dr. Jeff Wang (Emory University). Audio editing by CardioNerds academy intern, Shivani Reddy. This episode is part of the CardioNerds Lipids Series which is a comprehensive series lead by co-chairs Dr. Rick Ferraro and Dr. Tommy Das and is developed in collaboration with the American Society For Preventive Cardiology (ASPC). Relevant disclosures: None Pearls • Notes • References • Guest Profiles • Production Team CardioNerds Cardiovascular Prevention PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Pearls - REDUCE-IT The Reduction of Cardiovascular Events with EPA-Intervention Trial (REDUCE-IT) trial was a large randomized controlled trial that showed a significant reduction in atherosclerotic cardiovascular disease (ASCVD) events with use of icosapent ethyl ester in secondary prevention patients and high risk primary prevention patients with diabetes and residual elevated triglycerides between 135 to 499 mg/dL on top of maximally tolerated statin therapy1. Despite the use of high intensity statin therapy, considerable residual risk for future atherosclerotic cardiovascular disease exists in patients with ASCVD.Elevated triglycerides (TGs) are an important marker of increased residual ASCVD risk2.There are two primary types of Omega-3 fish oils: eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Omege-3 fish oils have been shown to lower triglyceride levels.Low-dose combination EPA and DHA has not exhibited incremental cardiovascular benefit in either primary prevention and secondary prevention patients on top of statin therapy3-5.REDUCE-IT showed the use of high dose EPA in patients with either ASCVD or DM and one additional risk factor, and relatively well-controlled LDL-C levels on maximally tolerated statin therapy and residual hypertriglyceridemia (TG 135-499 mg/dL) results in significant reductions in cardiovascular events over a median follow-up period of 4.9 years1. Show notes - REDUCE-IT Multiple epidemiologic and Mendelian randomization studies have established elevated triglyceride (TG) levels as an important risk factor for atherosclerotic cardiovascular events6-8. However previous clinical trials using TG-lowering medication such as niacin, fibrates and low dose omega-3 fish oil have not shown to reduce cardiovascular events when added to statin therapy in patients with or without ASCVD,9,10.The JELIS trial first demonstrated a significant reduction in cardiovascular events when 1.8g daily of eicosapentaenoic acid (EPA) was added to low-intensity statin therapy in patients with ASCVD and hypercholesterolemia, However, the trial was limited due to open label design without placebo, use of low doses of background statin therapy, and geographic/demographic limitations to participants in Japan11.In a large international multicenter randomized controlled trial, the Reduction of Cardiovascular Events with Icosapent Ethyl–Intervention Trial (REDUCE-IT) randomized 8,179 patients with established atherosclerotic heart disease or diabetes and an additional risk factor, on maximally tolerated statin therapy, to 4 gm/day of icosapent ethyl (a highly purified and stable EPA ethyl ester) or miner...

Brian Asbill, MD, board certified in Cardiovascular Diseases and Clinical Lipidology, had a career defining moment back in 2013 (he'll talk about this during the podcast). One of his patients, who had already survived two open heart surgeries and was still experiencing chest pain, came in to see him after a recommendation for a third surgery by a different doctor. Brian had a book in his office by Caldwell Esselstyn called Prevent and Reverse Heart Disease, which he decided to share with the patient. This book, which recommended switching to a plant-based diet, changed this patient's life. Three months later and 27 pounds lighter, he no longer needed many of his medications and his chest pain was gone.  This began Brian's path to Lifestyle Medicine, becoming the first board certified physician in Lifestyle Medicine in 2017. Brian co-founded Ruckus Health, dedicated to supporting people holistically in uncovering their innate ability to live in physical, mental, emotional and spiritual balance. Dr. Asbill is a Fellow of the American College of Cardiology and is a professional member of the American College of Physicians and the North Carolina Medical Society. Key Takeaways:   Finding Lifestyle Medicine Career as a cardiologist Transitioning to a whole food, plant-based diet Detecting cardiovascular disease if you're asymptomatic Reversing cardiovascular disease  Cardio protection with plant-based diets Foods that are a no-go  The 6 pillars of Lifestyle Medicine Stress management tips  

New study reveals fresh avocado-substituted diet significantly changes lipid profile University of the Pacific, February 1, 2022  According to the recently released 2015-2020 Dietary Guidelines for Americans, small shifts in food choices can make a big difference; including a shift from solid fats to oils, like the oil in fresh avocados. On the heels of this advice, a new meta-analysis, published in the Journal of Clinical Lipidology, adds to the growing body of research that supports the use of avocados in lieu of solid fats (and foods that have higher saturated fat content) to significantly change lipid profiles. The research, “Impact of avocado-enriched diets on plasma lipoproteins, looked at 10 unique avocado studies with 229 participants, assessing the impact of avocados on cholesterol levels. Researchers found avocado consumption (1 to 1.5 per day) significantly reduced total cholesterol (TC), “bad” low density lipoprotein cholesterol (LDL-C) and triglycerides (TG) when they were substituted for sources of saturated fat. Additionally, avocado consumption did not impact “good” high density lipoprotein cholesterol (HDL). However, the optimal amount of avocado and frequency of use needs further evaluation along with the nutritional similarities and differences between other different MUFA sources. Larger trials looking at the impact of avocados on major adverse cardiovascular events are warranted. (See conclusion of study) 20 mins of daily exercise at 70 may best stave off major heart disease in late old age Any physical activity is better late than never but earlier in older age, better still University of Padua (Italy), February 15, 2022 Twenty minutes of daily moderate to vigorous exercise in early old age (70-75) may best stave off major heart disease, including heart failure, in late old age (80+), suggests research published online in the journal Heart. The findings reinforce the maxim of ‘better late than never,' when it comes to exercise, but earlier on in older age is better still, concludes a linked editorial. To plug this knowledge gap, the researchers drew on data from the Progetto Veneto Anziani (ProVA), a study of 3099 older Italians (65 and above). The final analysis included 2754 participants with complete data, of whom 1398 were women (60%). The largest reduction in risk was observed for new cases of coronary heart disease and heart failure in late old age. No significant association between physical activity and stroke was observed.  Most of the participants had stable active physical activity patterns over time. Patterns of stable-high physical activity were associated with a significantly (52%) lower risk of cardiovascular disease among men compared with those with stable-low patterns. The greatest benefits seemed to occur at the age of 70. Risk was only marginally lower at the age of 75, and no lower at the age of 80-85, suggesting that improving physical activity earlier in old age might have the most impact, say the researchers.   Psilocybin treatment for major depression effective for up to a year for most patients, study shows Johns Hopkins University, February 15, 2022 Previous studies by Johns Hopkins Medicine researchers showed that psychedelic treatment with psilocybin relieved major depressive disorder symptoms in adults for up to a month. Now, in a follow-up study of those participants, the researchers report that the substantial antidepressant effects of psilocybin-assisted therapy, given with supportive psychotherapy, may last at least a year for some patients. A report on the new study was published on Feb. 15, 2022 in the Journal of Psychopharmacology. “Our findings add to evidence that, under carefully controlled conditions, this is a promising therapeutic approach that can lead to significant and durable improvements in depression,” says Natalie Gukasyan, M.D., assistant professor of psychiatry and behavioral sciences at the Johns Hopkins University School of Medicine. She cautions, however, that “the results we see are in a research setting and require quite a lot of preparation and structured support from trained clinicians and therapists, and people should not attempt to try it on their own.” The researchers reported that psilocybin treatment produced large decreases in depression, and that depression severity remained low one, three, six and 12 months after treatment.  Prevent memory loss with a powerful nutrient in cucumbers Salk Institute for Biological Studies, February 15, 2022 The results of a recent study are offering new hope that avoiding memory loss related to aging as well as Alzheimer's disease could be as simple as eating more cucumbers. Many older adults resign themselves to memory loss as part of the aging process. However, a study out of the the Salk Institute for Biological Studies has shown that this doesn't have to be the case. The health benefits of cucumbers are many, and one of them seems to be better memory and even the prevention of Alzheimer's disease. Researchers working with mice that normally developed the symptoms of Alzheimer's (including memory loss) discovered that a daily dose of a flavonol called fisetin prevented these and other related impairments. This improvement occurred despite the continued formation of amyloid plaques, the brain proteins commonly blamed for Alzheimer's. A natural food cure for memory loss The compound fisetin is found in numerous vegetables and fruits but is especially concentrated in strawberries and cucumbers. This flavonol is quite effective in stopping memory loss in mice and holds hope for humans as well. Polluted air may pollute our morality Columbia University Business School, February 7, 2022  Exposure to air pollution, even imagining exposure to air pollution, may lead to unethical behavior, according to findings published in Psychological Science, a journal of the Association for Psychological Science. A combination of archival and experimental studies indicates that exposure to air pollution, either physically or mentally, is linked with unethical behavior such as crime and cheating. The experimental findings suggest that this association may be due, at least in part, to increased anxiety. “This research reveals that air pollution may have potential ethical costs that go beyond its well-known toll on health and the environment,” says behavioral scientist Jackson G. Lu of Columbia Business School, the first author of the research. “This is important because air pollution is a serious global issue that affects billions of people—even in the United States, about 142 million people still reside in counties with dangerously polluted air.” Previous studies have indicated that exposure to air pollution elevates individuals' feelings of anxiety. Anxiety is known to correlate with a range of unethical behaviors. Lu and colleagues hypothesized that pollution may ultimately increase criminal activity and unethical behavior by increasing anxiety. In one study, the researchers examined air pollution and crime data for 9,360 US cities collected over a 9-year period. The air pollution data, maintained by the Environmental Protection Agency, included information about six major pollutants, including particulate matter, carbon monoxide, nitrogen dioxide, and sulfur dioxide. The researchers found that cities with higher levels of air pollution also tended to have higher levels of crime. This association held even after the researchers accounted for other potential factors, including total population, number of law enforcement employees, median age, gender distribution, race distribution, poverty rate, unemployment rate, unobserved heterogeneity among cities (e.g., city area, legal system), and unobserved time-varying effects (e.g., macroeconomic conditions). “Our findings suggest that air pollution not only corrupts people's health, but also can contaminate their morality,” Lu concludes. (Videos) 1. Libtard lunatic accuses unmasked kids of homicide calls em “Biological weapons” (after music) 2.  I Will Sacrifice Trophies for Bodily Autonomy   3. Charles Eisenstein: Why Normal Is Never Coming Back 4. Jonathan Haidt & Yuval Noah Harari: Adapting to Change in an Accelerating World (16:00) OTHER NEWS OPED:  The Earth Belongs to America Caitlin Johnstone, February 14, 2022The Wall Street Journal has an article out titled “U.S. Aims to Thwart China's Plan for Atlantic Base in Africa“, subtitled “An American delegation wants to convince Equatorial Guinea against giving Beijing a launchpad in waters the U.S. considers its backyard.”The article quotes the former U.S. Assistant Secretary of State for African Affairs Tibor Nagy saying, “We'd really, really not like to see a Chinese facility” on the Atlantic, and discusses “American concern about China's global expansionism and its pursuit of a permanent military presence on waters the U.S. considers home turf.”The Quincy Institute's Trita Parsi has discussed the irony of WSJ yelling about China's “global expansionism” over a potential military base in Equatorial Guinea without applying that label to the U.S., when the U.S. has hundreds of times the number of foreign military bases as China. Antiwar's Daniel Larison wrote an article back in December eviscerating the ridiculous claim that a military base some six thousand nautical miles from the U.S. coastline could be reasonably framed as any kind of threat to the American people.But what really jumps out is the insane way the U.S. political/media class routinely talks about virtually every location on this planet as though it is a territory of the United States.The Wall Street Journal referring to the entire Atlantic Ocean as “America's backyard” and “waters the U.S. considers home turf” follows a recent controversy over the U.S. president proclaiming that “Everything south of the Mexican border is America's front yard.” This provoked many references to the so-called “Monroe Doctrine”, a nineteenth-century imperialist assertion that Latin America is off limits to any power apart from the United States, effectively declaring the entire Western Hemisphere the property of Washington, DC.It also follows another incident in which Press Secretary Jen Psaki remarked on the ongoing tensions around Ukraine that it is in America's interest to support “our eastern flank countries”, which might come as a surprise to those who were taught in school that America's eastern flank was not Eastern Europe but the eastern coastline of the United States.The casual way these people say such things reflects a collectively held worldview that you won't find on any official document or in any schoolchild's textbook, but which is nonetheless a firmly held perspective among all the drivers of the modern empire: that the entire world is the property of the U.S. government. That the U.S. is not just the most powerful government in the world but also its rightful ruler, in the same way Rome ruled the Christian world.It's not something they can come out and directly say, because admitting they see themselves as the rulers of the world would make them look tyrannical and megalomaniacal. But it's certainly something they believe.They're about as obvious about it as could be. They make almost no effort to conceal it. And yet you'll still get empire apologists like Michael McFaul saying nonsense like this: McFaul knows very well that the U.S. is an imperial power and that it demands a very large “sphere of influence”.Would you like to see a picture of America's sphere of influence? Here you go:To live in the western world is to be constantly inundated with made-up stories about tyrants who want to terrorize the world while living under a globe-spanning power structure that is actually terrorizing the world. It's just so bizarre watching these imperial spinmeisters try to frame nations like China and Russia as freakish and backwards while working to literally rule the world like a comic book super villain.The U.S.-centralized empire is quantifiably the single most destructive and evil power structure in today's world. We shouldn't want anyone to rule over the entire planet with an iron fist, but these monsters are the very least qualified among us to do so. World's Rivers Awash in Pharmaceuticals, Historic Study Reveals Researchers who examined water samples from over 1,000 locations warn that “pharmaceutical pollution poses a global threat to environmental and human health.”Common Dreams. February 14, 2022 Underscoring the value of collaboration, experts from around the world on Monday unveiled what they described as the first “truly global study” of pharmaceutical drugs contaminating rivers, which has “deleterious effects on ecological and human health.”The historic analysis, published in the journal Proceedings of the National Academy of Sciences, involved 127 authors from 86 institutions. They examined surface water samples from 1,052 sites in 104 countries—including 36 that had never been monitored before— across all continents for 61 different active pharmaceutical ingredients (APIs).Sample sites ranged from an Indigenous community in Venezuela where modern medicine is not used to highly populated urban areas such as Delhi, London, and New York City. Researchers also gathered samples from regions with political instability, including Baghdad, Nablus in the Palestinian West Bank, and Cameroon's capital, Yaoundé.The United States was the “most extensively studied” nation, with samples collected at 81 locations along 29 rivers across Colorado, Florida, Hawaii, Iowa, Missouri, Nevada, New York, and Texas. Samples were also taken in every European Union member state except MaltaThe paper notes that all four contaminants detected on every continent—caffeine, nicotine, acetaminophen or paracetamol, and cotinine—are “considered either lifestyle compounds or over-the-counter APIs.” Another 14 APIs, including various antidepressants and antihistamines, were found on all continents except Antarctica.Lead author John Wilkinson of the University of York told Carrington that “the World Health Organization and U.N. and other organizations say antimicrobial resistance is the single greatest threat to humanity—it's a next pandemic.” “In 19% of all of the sites we monitored, the concentrations of [antibiotics] exceeded the levels that we'd expect to encourage bacteria to develop resistance,” he said. 15 Monkeys Have Reportedly Died While Testing Elon Musk's Midlife Crisis Brain Chip TheGamer.com, February 12, 2022Neuralink, an Elon Musk-owned company that develops brain chip technology, has attracted controversy once more. Animal trials of the brain chips have been linked to the deaths of 15 monkeys used in experimentation, with only seven said to have survived. These allegations come from the Physicians Committee for Responsible Medicine (PCRM), which says it has discovered this through over 700 pages of documents acquired through the University of California Davis. The apparent deaths span 2017 to 2020, which if true, would explain why human experimentation was pushed back two years from its projected date. The allegations come from reports in Business Insider and the New York Post. The sources say that monkeys used in animal trials of the Neuralink chips – which are apparently threaded into their brains – undergo “extreme suffering”. Both physical and neurological side effects are reported, ranging from brain haemorrhaging to self-harming behaviour. In one instance, a monkey was found to have missing fingers and toes, “possibly from self-mutilation or some other unspecified trauma”. Others are reported to have died of infection as a result of poor care after the chip was inserted. This report is a far cry from a video shared last year, which portayed a monkey calmly playing Pong. The company claims that the game was being played with the chip, without the need for a controller and using brain activity alone. Human trials were originally said to start in 2020, but this was pushed back to 2022. Recent reports say that the company is still going ahead with these plans, and has already started hiring for the experimentation.   US west ‘megadrought' is worst in at least 1,200 years, new study says University of California, Los Angeles, 15 Feb 2022  The American west has spent the last two decades in what scientists are now saying is the most extreme megadrought in at least 1,200 years. In a new study, published on Monday, researchers also noted that human-caused climate change is a significant driver of the destructive conditions and offered a grim prognosis: even drier decades lie ahead. “Anyone who has been paying attention knows that the west has been dry for most of the last couple decades,” says Park Williams, a climate scientist at the University of California, Los Angeles and the study's lead author. “We now know from these studies that is dry not only from the context of recent memory but in the context of the last millennium.” The research builds on conclusions from a previous study, also led by Williams, that ranked the period between 2000 and 2018 as the second driest in 12 centuries. The last two incredibly dry years – which were marked by record-setting heatwaves, receding reservoirs, and a rise in dangerously erratic blazes that burned both uncontrollably and unseasonably – were enough to push this period into first. Worryingly, the west is experiencing a point on an upward trajectory, the researchers warn. In the summer of 2021, both Lake Mead and Lake Powell – the largest reservoirs in North America – reached record-low levels. Nearly 65% of the American west is experiencing in severe drought according to the US drought monitor, even after record rainfall hit some areas late last year. For the first time, federal official curbed allocations from the Colorado River Basin, which supplies water and power for more than 40 million people. Wildfires in the last two years have left behind more blackened earth than ever before and performed feats never thought possible. California Lawmakers Fast-Tracking Child Health Bills to Erode Parental Rights ‘It's an underhanded move, meant to silence parents and hobble grassroots efforts across our state' California Globe, February 9, 2022 California lawmakers have chosen to fast-track several key child health bills that will further erode parental rights and infringe on parents' ability to maintain medical freedom. Specifically, three fast-tracked bills involve 1) forced COVID-19 vaccinations for children for school enrollment, 2) allowing minor children to make their own vaccine decisions away from a parent, and 3) require health care staff to complete cultural humility training to provide trans-inclusive health care. The Globe spoke with Karen England, Executive Director of the Capitol Resource Institute (CRI), a pro-family public policy organization educating, equipping, and engaging California citizens for 34 years. England shared her grave concerns about the bills, as well as the legislative processes being circumvented. “Typically, a bill must be in print for 30 days before it is acted upon, to give Californians time to read and understand the bill. But by conveniently suspending this established rule (Joint Rule 55 & Article IV Section 8(a)), the legislature is denying individual citizens and organizations like CRI the right to properly review and respond to these bills before they are passed,” England said. “It's an underhanded move, meant to silence parents and hobble grassroots efforts across our state.” The point of this rule is to give Californians time to read and understand these bills. “The fact is that they want to slide these bills through when there is plenty of time,” England said. “This should concern everyone.” 3,573 Fetal Deaths in VAERS Following COVID-19 Vaccines – 1,867% Increase Over Non-COVID Vaccines Brian Shilhavy, Health Impact News The U.S. Government's Vaccine Adverse Events Reporting System (VAERS) database was updated this past Friday, February 11, 2022, and it is now reporting that there have been 1,103,893 cases of injuries and deaths following COVID-19 vaccines since December of 2020, when the FDA issued emergency use authorizations for the COVID-19 vaccines.  By way of contrast, there were 918,856 cases of injuries and deaths following all FDA-approved vaccines for the previous 30+ years, from 1990 through November of 2020.  So there have been more injuries and deaths recorded in VAERS during the past 14 months following COVID-19 vaccines, than there were for the previous 30+ years combined following all vaccines recorded in VAERS. This most recent update of VAERS shows that there have now been 3,573 fetal deaths following COVID-19 vaccines.  To arrive at the number of fetal deaths recorded in VAERS I had to test several different searches on listed “symptoms” and then see if the search results documented fetal deaths, since there is no demographic for “fetal deaths.” The following is the current list of “symptoms” in VAERS that reveals fetal deaths: Aborted pregnancy Abortion Abortion complete Abortion complicated Abortion early Abortion incomplete Abortion induced Abortion induced incomplete Abortion late Abortion missed Abortion of ectopic pregnancy Abortion spontaneous Abortion spontaneous complete Abortion spontaneous incomplete Ectopic pregnancy Ectopic pregnancy termination Ectopic pregnancy with contraceptive device Foetal cardiac arrest Foetal death Premature baby death Premature delivery Ruptured ectopic pregnancy Stillbirth This list may not be exhaustive. But if we use the exact same search using these symptoms, we can compare “apples to apples” in examining fetal deaths following COVID-19 vaccines as compared to fetal deaths following all non-COVID vaccines. Here are the yearly averages: 82 fetal deaths per year following non-COVID vaccines 3063 fetal deaths per year following COVID-19 vaccines

As part of my Season 2 Launch Series, these episodes are a collection of short length talks on defining health. The starting point for changing our lifestyles begins with examining our thoughts around health. So this a thought experiment designed to challenge the way you've previously thought about health to help redefine it for yourself. That said, my next Launch Series guest is Dr. Nicole Harkin, MD. Dr. Harkin is a preventive cardiologist board certified in Internal Medicine, Cardiology, Echocardiography, Nuclear Cardiology, and Clinical Lipidology. She is founder of Whole Heart Cardiology - a preventive telecardiology practice with the mission of providing cardiac optimization through precision and lifestyle medicine. Her passion comes through on her Instagram page where she discusses topics on preventing heart disease through healthful, sustainable lifestyle changes. And Dr. Harkin is here to tell all of us how she defines health. I hope her message helps to redefine what health means for you.Show Notes:Connect with With Dr. Nicole Harkin, MDWebsite Instagram Facebook Connect with Dr. Jonar, MD: Website Instagram Facebook Linkedin Twitter Related Podcast Episodes You Will Enjoy:020. What's Missing From Your Health with Dr. Saray Stancic, MD012. Food is Medicine: The Power of Plant Food with Dr. SiriChand Khalsa, MD014. This Surgeon Operates First On Your Diet with Dr. Sung Won, MD001. The Lives that Saved Mine with Dr. Jonar de Guzman, MDHOW CAN I SUPPORT THIS PODCAST?Download, Listen, Subscribe, Rate & Review: Glass Half Healthy on Apple PodcastTell Your Friends & Share Online!Thanks to my intern, the wonderful and smart Amelia Liu, to Jacob Ferrer for their production help, and to StockSounds for the music. And to YOU! Thank you for listening!Disclaimer:This podcast is intended for educational purposes only and isn't medical advice so please talk to your primary physician for that. In addition, the views and opinions expressed by me are my own and not that of my former, current or future employer. This also applies to my guests. Finally, we do our best to make every effort to relay correct information, but don't guarantee its accuracy. Thank you for listening.

Listen Now Preventing adult heart attacks in early childhood? Don Wilson, M.D., explains why it's absolutely within REACH. Children with high cholesterol, especially those who have a genetic cause, such as familial hypercholesterolemia, also know as fH, are at a higher risk for developing premature heart disease, such as heart attack or stroke as they become adults. At the forefront of developing guidelines for lowering this risk, Dr. Wilson details how the Risk Evaluation to Achieve Cardiovascular Heath, or REACH, clinic at Cook Children's is putting those guidelines to work and changing the outcomes for these in the future, and saving the lives of parents today. Meet the speaker Dr. Don Wilson Related InformationRisk Evaluation to Achieve Cardiovascular Health (REACH) Clinic Diabetes Program Endocrinology Program They're Active, Eat Healthy, and Have High Cholesterol-Why? Harper's Story Kids at Risk of Smoke Exposure in Smoke-Free Areas? A Simple Blood Test Could Save Your Child's Life The Unique Risks of Being a Woman with Diabetes Number of Children and Adolescents Who are Obese 10 Times Higher than 40 Years Ago Transcript: 00:00:03 Host: Hello, and welcome to Cook Children's Doc Talk. Today we're talking with Dr. Don Wilson about genetic dyslipidemia, and cardiovascular disease. But first, here's just a little about Dr. Wilson. He is board certified in pediatrics, pediatric endocrinology and clinical lipidology. He is the founder and currently the medical director of Cook Children's REACH program, one of the first cardiovascular risk assessment clinics for children and adolescents in the nation. Dr. Wilson is a fellow of the National Lipid Association and an associate editor for The Journal of Clinical Lipidology and a member of the

On this episode, Dr. Tom Dayspring and Faraz Khan discuss the basics of lipids that you need to know about: 1. What are lipids and lipoproteins? 2. Why is cholesterol very good for you - and very bad for you - but here is how to know which one you have? 3. How to review your lipid numbers after your next blood test - plus 1-2 secret tests you MUST start getting from now on. Get the full show notes here: https://antiaginghacks.net/podcast/lipids-cholesterol-apob-hdl-ldl/ Thomas Dayspring is a Fellow of both the American College of Physicians and the National Lipid Association and is certified in internal medicine and clinical lipidology. After practicing in NJ for almost 40 years, he moved to VA and served as an educational director for a nonprofit cardiovascular foundation and later as a Chief Academic Advisor for two major Cardiovascular labs until mid-2019. Currently he is a cardiovascular educational research assistant & clinical lipidologist at Attia Medical. Career-wise he has given over 4000 domestic and international lectures, including over 600 CME programs. Until 2019 he was an Associate Editor of the Journal of Clinical Lipidology. He was the recipient of the 2011 National Lipid Association's Presidents Award for services to clinical lipidology. He is very active on twitter and has well over 15K followers (@DrLipid)

Dr. Nicole Harkin, MD  is board certified in Internal Medicine, Cardiology, Echocardiography, Nuclear Cardiology, and Clinical Lipidology. She founded Whole Heart Cardiology, with the mission of providing patient centred cardiac care, evidence-based nutritional guidance, and personalised lifestyle plans. Nicole is just a great example of what we need more of, doctors that follow and prescribe to scientific evidence. Which is many cases points to plant centric diets in order to foster a healthy physiology.The key topics in today's episode:- Facts about heart disease- Defining a healthy heart- Symptoms of an unhealthy heart-  How much exercise is good- Foods to eat for heart health- Sugar in fruit- Being up to date with science- Why we eat the rainbow-  The effect of meat, dairy and eggs- How sodium affects your body- Raising healthy kidsVideo Version: https://youtu.be/VObv9sJNTLwConnect with Nicole:Website | https://www.wholeheartcardiology.com/Instagram | https://www.instagram.com/nicoleharkinmd/Connect with me:Instagram | @plant.paradigmInstagram | @tomsimakYouTube | The Plant ParadigmTwitter | @plantparadigmWebsite | www.theplantparadigm.comSupport the show | Buy me a coffeeSubscribe to the podcast:Apple | Spotify | Stitcher |Stay happy,Eat plants,Peace

In this episode, host Mark Gomez, MD, and his guests, Louis Malinow, MD, and Bonnie Kastin, RDN, LDN, break down common diets and offer practical tips on how to establish sustainable, healthy eating habits. In Greek, the word “diet” means “way of life.” For so many people, day-to-day life revolves around food. With all the choices available and a fast food restaurant on every corner, it's more important than ever to focus on healthier eating. Almost all diseases can be prevented or delayed with better nutrition. Eating a standard American diet (ahem, processed food, a.k.a. anything in a box or a bag) can seriously affect your health! Since almost everyone relies on processed food on a regular basis, this could be troubling. Feeling overwhelmed? Don't worry. Small changes in your diet can make a big difference in your health. There are three things we can control: what we eat, how much we eat and when we eat. As diet culture evolves, various diets rise and fall in popularity. Fasting, keto, counting macros – which dietary trends are the healthiest to follow? And is it possible to change your eating habits if others in your household don't? Guests Louis Malinow, MD - ASH certified hypertension specialist; Diplomate, American Board of Clinical Lipidology; Director of Education and Clinical Excellence at MDVIP. Bonnie Kastin, RDN, LDN - Registered dietitian nutritionist and licensed dietitian nutritionist, Suburban Gastroenterology, LTD.

In this episode, Board Certified Cardiologist Dr. Nicole Harkin and I discuss Whole Heart Health including answers to the following questions:- How do you identify and reduce cardiovascular risk if you have a strong family history? - How much does stress contribute to the development of heart disease and what can we do to reduce stress?- Does heart disease really begin in childhood?- How do we encourage more young people to engage in a heart healthy lifestyle?- Which diet is best for our heart and how much alcohol can/should we drink?- Is there a metabolic benefit to intermittent fasting?- In the prevention or treatment of cardiovascular disease, is there a place in for non-traditional treatments and therapies such as supplements, antioxidants,  acupuncture, reiki, herbs?***************Dr. Harkin is Board Certified in Internal Medicine, Cardiology, and Clinical Lipidology.  After completing medical school at Boston University, Dr. Harkin received her Internal Medicine training at NYU and Cardiology fellowship at Columbia University.  She is the founder of Whole Heart Cardiology, a preventive telecardiology practice. She is passionate about preventing heart disease through healthful, sustainable lifestyle changes. Dr. Harkin is based in San Francisco, but she is available for consultations to patients in CA, NY, and FL.For more from Dr. Harkin check out:www.wholeheartcardiology.com and on IG @nicoleharkinmd***************Thanks so much for listening!  If you enjoyed the show and want to hear more, please like, subscribe and share!You can always find more information on my website:www.drlexlifestylemedicine.comand....If you love the music like I do, you can find more at:www.therealmichaelvm.com/music*****************All my love & gratitude to:my guest: Dr. Nicole Harkin,my inspiration: my patients,my idea guy & confidence booster: Edwardmy intro crew: Izzy, Lance & Lucia,my tech & equipment guy: Pop,my music & sound guy: Mike VM,my mascot: Jules, my creative director & cheerleader: Emily Newman VM,my love, Michael. 

In today's episode, Ali discusses the auditioning process for movies and television roles (0:57). He discusses how he went from stand-up comedy to acting and how he got an agent. He then discusses some memorable (and not so memorable) auditions. Next, Asif discusses the ketogenic diet (28:53). He talks about what makes up a ketogenic diet and its use in epilepsy. Asif then discusses its more controversial use in weight loss and diabetes.  The opinions expressed are those of the hosts, and do not reflect those of any other organizations. This podcast and website represents the opinions of the hosts. The content here should not be taken as medical advice. The content here is for entertainment and informational purposes only, and because each person is so unique, please consult your healthcare professional for any medical questions. Music courtesy of Wataboi and 8er41 from Pixabay Contact us at doctorvcomedian@gmail.com Follow us on Social media: Twitter: @doctorvcomedian Instagram: doctorvcomedian The Ketogenic Diet for Epilepsy, Johns Hopkins: https://www.hopkinsmedicine.org/neurology_neurosurgery/centers_clinics/epilepsy/diet-therapy.html Ketogenic Diet for Weight loss, Canadian Family Physician, 2018: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371871/ Review of current evidence and clinical recommendations on the effects of low-carbohydrate and very-low-carbohydrate (including ketogenic) diets for the management of body weight and other cardiometabolic risk factors: A scientific statement from the National Lipid Association Nutrition and Lifestyle Task Force, Journal of Clinical Lipidology, 2019: https://www.sciencedirect.com/science/article/pii/S1933287419302673 Low-Carb and Ketogenic Diets in Type 1 and Type 2 Diabetes, Nutrients, 2018: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566854/

Nicole Harkin, MD, FACC, is board-certified in Internal Medicine, Cardiology, Echocardiography, Nuclear Cardiology, and Clinical Lipidology. In this episode, Dr. Harkin details how cholesterol affects your cardiovascular health and different ways to improve it. We also go into Dr. Harkin’s journey into the plant-based movement. You can find Dr. Harkin at: Instagram: @nicoleharkinmd Facebook: Whole Heart Cardiology www.wholeheartcardiology.com

Siobhan Huggins is an independent researcher focused on the science of keto, carnivory, inflammation, insulin resistance and how they all interact with each other. Over the past four years she has lost 80 lbs (36kg or 5.5stone), put chronic depression into remission, and made numerous health improvements - all from going on a ketogenic (and eventually carnivorous) diet. She hopes to continue learning the science so she can share it with others, in the hopes of better understanding why ketogenic and carnivorous diets appear to work for improving so many conditions, and why people sometimes struggle even when implementing these dietary strategies and doing everything "right". She is on the board of The Citizen Science Foundation, and is a frequent contributor to CholesterolCode.com where she posts on topics like lipids and immunity, heart disease, and inflammation, as well as the results of her self experiments with diet.In this episode Siobhan explains how she improved her depression with a ketogenic diet. She tells us how she learned about lipids and got involved with Dave Feldman of CholesterolCode.com after meeting him at the 2018 KetoFest in New London, Connecticut. We learn about some of her self-experiments, the results of medical tests and the importance of establishing a baseline. She talks about her relationship with her doctor and how she builds that trusting and respectful relationship.Siobhan explains the lipid triangle.We have a couple of corrections from Siobhan:Two corrections on my part, though. Apparently Dr Attia only recommends Therapeutic Lipidology – looking over old blog posts on CholesterolCode, I do mention starting with this and then went on to read Clinical Lipidology right after, so that is correct. With that said, I'm not sure where I saw Clinical Lipidology recommended, but it wasn't from Attia. Additionally, the correct quote of what he says is “Anyone aspiring to be a lipid savant […] probably ought to get a copy.” From Part III of the straight dope on cholesterol series. Not “citizen lipidologist” as I stated.Resources MentionedClinical Lipidology: A Companion to Braunwald's Heart Disease, 2e - Dr Christine Ballantynehttps://amzn.to/2KmmBIwTherapeutic Lipidology (Contemporary Cardiology) - Michael H. Davidson , Peter P. Toth , Kevin C. Makihttps://amzn.to/3pgWFwpCholesterolcode.com https://cholesterolcode.com/Report https://cholesterolcode.com/report/Labs https://cholesterolcode.com/lab-testing/Lean mass hyper responder https://cholesterolcode.com/lmhr/Citizen Scientist Foundation https://citizensciencefoundation.org/The Obesity Code - Dr Jason Funghttps://amzn.to/3aCYUWK2KetoDudes podcast http://2ketodudes.com/ Fat Head movie with Tom Naughton

By Michael Tetreault, Editor-in-Chief We sit down with Dr. Daniel Stock, the Founding Physician at PureHealth Functional Family Medicine. Dr. Stock's office is located in Noblesville, Indiana. After 18 years of being hospital-employed, Dr. Daniel Stock has opened the doors to his new functional family medicine practice. The practice is one of only two functional family medicine practices in the state of Indiana, but is the sole practice to provide care through Direct Primary Care (DPC), and without involving health insurance. As a DPC practice, PureHealth Functional Family Medicine enables patients to pay a flat, monthly fee for unlimited health care, while reserving their health insurance for specialty physician visits and hospitalizations. “I want to offer my patients all that Functional Family Medicine offers at a flat price, while also providing them care when they need it,” said Dr. Daniel Stock, founding physician of PureHealth Functional Family Medicine. “The best part of functional medicine is tackling both common or acute diseases and chronic complex issues from lacerations and sore throats, to Chronic Inflammatory Response Syndrome, Fibromyalgia and even Parkinson's Disease.” Despite practicing for three decades, Dr. Stock has most recently learned of an innovative way of reversing Alzheimer's Disease. He says he believes that finding out all the elements that cause a person to become ill is the best way to be able to treat a chronic disease. “Whether my patient is battling the common cold, or Alzheimer's Disease, my goal is to realize and achieve ‘good healthcare,' and to that, I believe in spending more time with each patient to inform them of their options, make decisions and plan out the best, next steps” said Dr. Stock. “I firmly believe most issues can be solved by lifestyle changes if caught early enough, and in an economical way. And, DPC functional medicine allows for that to occur.” Dr. Stock completed his undergraduate degree at Notre Dame University, his medical degree at Indiana University, and internship at St. Vincent's Hospital in Indianapolis. He began practicing primary care in 1989. A founding diplomate of the American Board of Clinical Lipidology, Dr. Stock is also a diplomate of the American Board of Anti-Aging and Regenerative Medicine. RESOURCES MENTIONED https://purehealthmed.com/ www.DirectPrimaryCare.com www.ConciergeMedicineFORUM.com https://freedomhealthworks.com/ www.ConciergeMedicineToday.com

Časovnica: [00:00:30] Aktualne teme: o nadaljevanju podcasta, projektu skupine evidance-based pristopa k prehrani in vadbi ter poskusu svetovnega rekorda v log liftu. [00:08:30] Kako je pot do naših ciljev lahko izvor sreče in zadovoljstva. Zakaj se moramo konstantno premikati proti nekemu cilju. O zanemarjanju prihodnosti in upiranju kratkoročnim ciljem ter zakaj je to pomembno pri delu na področju fitnesa in zdravja. [00:37:15] Ali je kava dober vir kofeina za športnike? O nevarnosti predoziranja s kofeinom z določenimi komercialno dostopnimi izdelki. [00:49:00] Omega-3 indeks. Kaj je in zakaj je pomemben? [01:22:15] Omega-3 indeks in športniki. Kako dosledni so športniki pri zagotavljanju potreb po omega-3? Zakaj športniki potrebujejo več omega-3 [01:37:15] Zaključek.   Omenjeni članki: Hipoteza rdeče kraljice: Brockhurst et al. (2014) ‘Running with the Red Queen: the role of biotic conflicts in evolution', Proceedings of the Royal Society B: Biological Sciences, 281(1797), p. 20141382. https://doi.org/10.1098/rspb.2014.1382 "Zanemarjanje prihodnosti": Frederick et al. (2002) ‘Time Discounting and Time Preference: A Critical Review', Journal of Economic Literature, 40(2), pp. 351–401.  https://doi.org/10.1257/002205102320161311 Vsebnost kofeina v kavi: McCusker et al. (2003). Caffeine Content of Specialty Coffees. Journal of Analytical Toxicology, 27(7), 520–522.  https://doi.org/10.1093/jat/27.7.520  Omega-3 index in zdravje: von Schacky, C. (2020) ‘Omega-3 index in 2018/19', Proceedings of the Nutrition Society, (October 2019), pp. 1–7. https://doi.org/10.1017/S0029665120006989Sarteret al. (2015) ‘Blood docosahexaenoic acid and eicosapentaenoic acid in vegans: Associations with age and gender and effects of an algal-derived omega-3 fatty acid supplement', Clinical Nutrition. Elsevier Ltd, 34(2), pp. 212–218. https://doi.org/10.1016/j.clnu.2014.03.003 Harris et al. (2018) ‘Erythrocyte long-chain omega-3 fatty acid levels are inversely associated with mortality and with incident cardiovascular disease: The Framingham Heart Study', Journal of Clinical Lipidology. Elsevier Inc, 12(3), pp. 718-727.e6. https://doi.org/10.1016/j.jacl.2018.02.010 Harris et al. (2016) ‘Red blood cell oleic acid levels reflect olive oil intake while omega-3 levels reflect fish intake and the use of omega-3 acid ethyl esters: The Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico–Heart Failure trial', Nutrition Research. Elsevier B.V., 36(9), pp. 989–994. https://doi.org/10.1016/j.nutres.2016.06.012 Harris et al. (2017) ‘The Omega-3 Index and relative risk for coronary heart disease mortality: Estimation from 10 cohort studies', Atherosclerosis. Elsevier Ltd, 262, pp. 51–54. https://doi.org/10.1016/j.atherosclerosis.2017.05.007 ALA nimajo enakih koristi kot EPA in DHA: Burdge et al. (2002) ‘Conversion of α-linolenic acid to eicosapentaenoic, docosapentaenoic and docosahexaenoic acids in young women', British Journal of Nutrition, 88(04), p. 411. https://doi.org/10.1079/BJN2002689 Wendland. (2006) ‘Effect of linolenic acid on cardiovascular risk markers: a systematic review', Heart, 92(2), pp. 166–169. https://doi.org/10.1136/hrt.2004.053538 Su et al. (2018) ‘Effect of dietary alpha-linolenic acid on blood inflammatory markers: a systematic review and meta-analysis of randomized controlled trials', European Journal of Nutrition. Springer Berlin Heidelberg, 57(3), pp. 877–891. https://doi.org/10.1007/s00394-017-1386-2 Jovanovski et al. (2017) ‘The effect of alpha-linolenic acid on glycemic control in individuals with type 2 diabetes', Medicine (United States), 96(21). https://doi.org/10.1097/MD.0000000000006531 Omega-3 index pri športnikih: Ritz et al. (2020). Dietary and Biological Assessment of the Omega-3 Status of Collegiate Athletes: A Cross-Sectional Analysis. PloS one, 15(4), e0228834. https://doi.org/10.1371/journal.pone.0228834 Davinelli et al. (2019). Relationship Between Distance Run Per Week, Omega-3 Index, and Arachidonic Acid (AA)/Eicosapentaenoic Acid (EPA) Ratio: An Observational Retrospective Study in Non-elite Runners. Frontiers in physiology, 10, 487. https://doi.org/10.3389/fphys.2019.00487   Sledite nam: Nenadov instagram: @nenad.feelgood Matjažev instagram: @matjaz.feelgood Feelgood Skupnost na Facebooku: https://bit.ly/feelgoodskupnost Spletna stran: https://www.feel-good.si   Poslušate nas lahko na: Podbean: https://bit.ly/podbean-zdp Stitcher: https://bit.ly/stitcher-zdp Pocket Casts: https://bit.ly/pocket-zdp Podcast Addict: https://bit.ly/addict-zdp Castbox: https://bit.ly/castbox-zdp iTunes: https://bit.ly/itunes-zdp  

While we are in an incredibly exciting time when it comes to preventing and reversing disease, issues such as misleading scientific research, imperfect policy, corporate financial interests, and other biases often act as roadblocks to enhancing the health of our population and our planet. Yet, when we recently reflected on a number of conversations from The Doctor’s Farmacy, we couldn’t help but hear a common and hopeful message. In this mini-episode, we revisit four conversations Dr. Hyman has had with guests on this podcast, each with a common refrain: Progress is being made and it’s happening fast! Michael Pollan is the author of the New York Times bestsellers Cooked, Food Rules, In Defense of Food, The Omnivore’s Dilemma, The Botany of Desire, and his latest book How to Change Your Mind, which is all about the new science of psychedelics. A longtime contributor to the New York Times Magazine, he also teaches writing at Harvard and the University of California, Berkeley where he is the John S. and James L. Knight Professor of Science Journalism. In 2010, Time magazine named him one of the one hundred most influential people in the world.Dr. Hallberg is a Medical Director at Virta Health and a Fellow of the Aspen Institute’s Health Innovator Fellowship and a member of the Aspen Global Leadership Network. She is also the Medical Director and founder of the Medically Supervised Weight Loss Program at Indiana University Health Arnett and an adjunct Professor of Clinical Medicine at the Indiana University School of Medicine. Dr. Hallberg is serving as Chair of the Board of Directors and Chair of the Scientific Advisory Council for The Nutrition Coalition. Dr. Hallberg is a diplomate of the American Board of Internal Medicine, American Board of Obesity Medicine, and The American Board of Clinical Lipidology and is a Registered Exercise Physiologist by the ACSM. She is also a Fellow of the Obesity Medicine Association and The National Lipid Association.David Wallace-Wells is the deputy editor of New York magazine and the author of the international bestseller The Uninhabitable Earth: Life After Warming, published in February 2019, which the New York Times called both “brilliant” and “the most terrifying book I have ever read.”Dr. Sonia Angell is a former Deputy Commissioner at the New York City Department of Health and Mental Hygiene (DOHMH), where she oversaw the Division of Prevention and Primary Care. Dr. Angell is a practicing physician, board certified in internal medicine, and on faculty at the College of Physicians and Surgeons of Columbia University and New York Presbyterian Hospital.Tune into Dr. Hyman’s full length conversation with Michael Pollan: https://DrMarkHyman.lnk.to/MichaelPollanTune into Dr. Hyman’s full length conversation with Dr. Sarah Hallberg: https://DrMarkHyman.lnk.to/DrSarahHallbergTune into Dr. Hyman’s full length conversation with David Wallace-Wells: https://DrMarkHyman.lnk.to/DavidWallaceWellsTune into Dr. Hyman’s full length conversation with Dr. Sonia Angell: https://DrMarkHyman.lnk.to/DrSoniaAngell See acast.com/privacy for privacy and opt-out information.

Dr. Sarah Hallberg is a diabetes expert, who is here to change the way we treat diabetes. Her number one weapon for reversing type 2 diabetes: a ketogenic diet.Dr. Hallberg is a Medical Director at Virta Health and a Fellow of the Aspen Institute’s Health Innovator Fellowship and a member of the Aspen Global Leadership Network. She is also the Medical Director and founder of the Medically Supervised Weight Loss Program at Indiana University Health Arnett and an adjunct Professor of Clinical Medicine at the Indiana University School of Medicine. Dr. Hallberg is serving as Chair of the Board of Directors and Chair of the Scientific Advisory Council for The Nutrition Coalition. Dr. Hallberg is a diplomate of the American Board of Internal Medicine, American Board of Obesity Medicine, and The American Board of Clinical Lipidology and is a Registered Exercise Physiologist by the ACSM. She is also a Fellow of the Obesity Medicine Association and The National Lipid Association.In this episode, Dr. Hallberg shares the benefits of a high fat, or ketogenic, diet. You may have heard that a ketogenic diet can be beneficial for your health—that it promotes weight loss, longevity, and enhanced cognitive function—and wondered if the hype is true. Tune into this week’s episode to find out. See acast.com/privacy for privacy and opt-out information.

Physician and exercise physiologist Dr. Sarah Hallberg is our interview guest today in Episode 1364 of “The Livin’ La Vida Low-Carb Show.” Dr. Sarah Hallberg from VitraHealth.com is the medical director at Virta Health. She is also the medical director and founder of the Medically Supervised Weight Loss Program at Indiana University Health Arnett and an adjunct professor of clinical medicine at the Indiana University School of Medicine. Dr Hallberg is a diplomate of the American Board of Internal Medicine, American Board of Obesity Medicine, and The American Board of Clinical Lipidology and is a Registered Exercise Physiologist by the American College of Sports Medicine. https://www.youtube.com/watch?v=da1vvigy5tQ   Listen in today as Jimmy talks with Sarah about her year long study, sustainability, the fact that people can maintain a ketosis for longer periods, not just a few months, using BHB as a method to track patient adherence which makes this a more reliable study than all the nutrition studies that use food logs, the role of blood tests, remotely supporting patients, and much more. Nutrient-Rich Vegetables in an Easy-to-Use Powder “JIMMY” at checkout to get 20% off your first order! NOTICE OF DISCLOSURE: Paid sponsorship GET A $39 BOTTLE OF OLIVE OIL FOR JUST A BUCK GET YOUR $39 BOTTLE FOR JUST $1 NOTICE OF DISCLOSURE: Paid sponsorship COUPON CODE JIMMY FOR 10% OFF ANY ORDER NOTICE OF DISCLOSURE: Paid sponsorship LINKS MENTIONED IN EPISODE 1364 – SUPPORT OUR SPONSOR: Keto friendly enchiladas! (COUPON CODE JIMMY FOR 10% OFF ANY ORDER) – SUPPORT OUR SPONSOR: The world’s freshest and most flavorful artisanal olive oils. Get your $39 bottle for just $1 – SUPPORT OUR SPONSOR: Get all the nutritious vegetables you need with Dr. Cowan’s Garden (“JIMMY” at checkout to get 20% off your first order!) – virtahealth.com, – @DrSarahHallberg, – TEDx talk: https://www.youtube.com/watch?v=da1vvigy5tQ – Ted Talks here: http://bjsm.bmj.com/content/early/2018/02/08/bjsports-2017-098500 – and here: https://link.springer.com/article/10.1007%2Fs13300-018-0373-9

Summary: In this episode our guest is Master Lipidologist, Dr. Peter Howard Jones from Baylor College of Medicine and the National Lipid Association. My guest host is Dr. Paul Williams, Clinician Educator extraordinaire from Philadelphia. We explore everything you’ll ever want to know about cholesterol and lipids. Are statins still king when it comes to cholesterol lowering? Should we be rushing to use PCSK9 inhibitors? Should we throw away older drugs like fibrates? Are nonpharmacologic therapies like niacin and fish oil worthwhile? Join us for this extensive conversation.   Disclosures: Dr. Jones is the Chief Science Officer at the National Lipid Association. He has served as a scientific advisor to Merck, Amgen and Sanofi.   Learning objectives: 1. Identify each individual's risk for cardiovascular disease and counsel them on benefits of therapy. 2. Learn to lower atherogenic lipids by any means necessary and understand the effects of the common lipid lowering drugs 3. Effectively counsel patients on benefits of lipid lowering drugs to promote patient buy in and adherence.   Clinical Pearls 1. Omega 3 fatty acids at 1,000 mg daily or more is useful for prevention of sudden death in post ACS patients. 2. Omega 3 fatty acids at dose of 4,000 mg per day is needed to lower triglycerides. Indicated if TG remain above 500 on first line therapy. 3. Hypertriglyceridemia with level above 500 on optimal statin dose, then consider addition of fibrate and/or omega-3 fatty acids. Uncertain clinical benefit in patient with moderate elevation (200-300) of triglycerides. 4. Statin intolerance can be overcome in most patients using the following methods: a. Same statin at lower dose b. Different statin c. Use of rosuvastatin or atorvastatin 3 times weekly 5. Statins are safe to take for at least 20 years and probably longer (this data is still being collected, but will be available in the future) 6. Withdrawal of statins at the end of life is not harmful and may be beneficial.   Links from the Show:   Studies that used fibrates for preventions of CV events: Helsinki Heart Study for primary prevention NEJM 1987 VA HIT Study for secondary prevention NEJM 1999   Withdrawal of statins at the end of life http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618294/   Expert Consensus on use of Non-Statin Drugs http://www.acc.org/latest-in-cardiology/ten-points-to-remember/2016/03/30/11/58/2016-acc-expert-consensus-decision-pathway-on-the-role-of-nonstatin   National Lipid Association recommendations for patient-centered management of dyslipidemia https://www.lipid.org/sites/default/files/Recommendations-Part-1.pdf   Recommended websites National Lipid Association The Heart.org (Medscape) Journal of Clinical Lipidology

Host: Alan S. Brown, MD, FNLA Guest: Harold Bays, MD, FNLA Dr. Alan Brown welcomes Dr. Harold Bays, President of the Southeast Lipid Association and President of the Louisville Metabolic and Atherosclerotic Research Center in Louisville, KY. Dr. Bays led a novel educational effort to provide an annual summary of clinical lipidology to readers of the Journal of Clinical Lipidology. With insightful commentaries of value to lipidologists and generalists alike, the annual summary is expected to pave new ground in the ongoing effort to keep clinicians up to date with the field.

Host: Alan S. Brown, MD, FNLA Dr. Harold Bays, Chair for the National Lipid Association's expert panel on Adiposity, Obesity, and Dyslipidemia, discusses with host Dr. Alan Brown the panel's consensus statement published in the Journal of Clinical Lipidology.

The Get Better Wellness Radio Show with host, Erin Chamerlik, The Real Food Revivalist. Larry Kaskel, MD board certified in Internal Medicine and Clinical Lipidology with 25 years of experience, discusses truths about cholesterol, LDL and HDL. Does raising HDL have any benefit? What are the side-effects seen with cholesterol-lowering drugs and do they have any benefit? How do diet and lifestyle factors play a role. Can we reverse type 2 diabetes, high cholesterol, high blood pressure and obesity? Visit GetBetterWellness.com to learn more. Erin offers a 4-DVD series taught before a live audience. You will learn to sort through the conflicting and confusing messages about nutrition. Science-based, straight-talkin' host, Erin Chamerlik is the Real Food Revivalist. Read the success stories HERE and join the Real Food Revival!    

Dr. Constantine E. Kosmas. HDL Functionality: An Emerging Concept in Clinical Lipidology. Recorded 2012-11-16.

Guest: Spencer Kroll, MD, PhD Host: Alan S. Brown, MD, FNLA The Food and Drug Administration has warned that patients taking cholesterol-fighting statins face a small increase in the risk of higher blood-sugar levels and of being diagnosed with diabetes. There has been conflicting information from several large trials about the effects of statin therapy on the development of diabetes and glycemic control. Join host Dr. Alan Brown and Dr. Spencer Kroll, diplomate of the American Board of Clinical Lipidology and a board certified Internist. He also serves on the board of directors of the Northeast Lipid Association and runs The Cholesterol Treatment Center, a lipid clinic in Marlboro, New Jersey. Brought to you by:

Guest: Eliot Brinton, MD, FAHA, FNLA Host: Larry Kaskel, MD The Women's Health Initiative trial reported that hormone replacement therapy increases the risks of coronary artery disease in postmenopausal women. Dr. Eliot Brinton, director of the metabolism section of the cardiovascular genetics department at the University of Utah School of Medicine in Salt Lake City, and a founding board member of the National Lipid Association and the American Board of Clinical Lipidology, discusses with host Dr. Larry Kaskel a new analysis of the Women's Health Initiative that disputes these findings. Dr. Brinton explores the various risks associated with estrogen, provides guidance on how to evaluate the use of estrogen in postmenopausal women, as well as the practice of stopping estrogen. Tune in to hear Dr. Brinton identify the evidence that supports the cardio-protective effects of estrogen as well the relationship between stroke and estrogen use. Brought to you by:

Guest: Carol Mason, ARNP Host: Larry Kaskel, MD Dr. Larry Kaskel is joined by Carol Mason, Clinical Director, Division of Preventive Cardiology University of Southern Florida. Ms. Mason will answer, "Why should any professional become a Clinical Lipid Specialist?". She will also discuss who is eligible, what are the requirements and how the ACCL differs from the American Board of Clinical Lipidology. Brought to you by:

Guest: W. Virgil Brown, MD Host: Larry Kaskel, MD Dr. Larry Kaskel welcomes Dr. Virgil Brown to Lipid Luminations. Dr. William Virgil Brown, Editor-in Chief of the Journal of Clinical Lipidology and Charles Howard Candler Professor of Medicine at Emory University School of Medicine. Tune in to hear about neclear physicist, John Gofman and the major contributions he made to science and how it affects cholesterol work today. Brought to you by: