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In this episode, Lyell K. Jones Jr, MD, FAAN, speaks with Noah A. Kolb, MD, who served as the guest editor of the October 2026 Peripheral Nerve and Motor Neuron Disorders issue. They provide a preview of the issue, which publishes on October 2, 2026. Dr. Jones is the editor-in-chief of Continuum: Lifelong Learning in Neurology® and is a professor of neurology at Mayo Clinic in Rochester, Minnesota. Dr. Kolb is a professor of neurological sciences at the Robert Larner College of Medicine at the University of Vermont in Burlington, Vermont. Additional Resources Read the issue: continuum.aan.com Subscribe to Continuum®: shop.lww.com/Continuum Continuum® Aloud (verbatim audio-book style recordings of articles available only to Continuum® subscribers): continpub.com/Aloud More about the American Academy of Neurology: aan.com Social Media facebook.com/continuumcme @ContinuumAAN Host: @LyellJ Full episode transcript available here Dr. Jones: The human brain is incredibly complex. That's one of the reasons we like to study it and care for patients with neurologic problems. But to translate cognition into action, we need a functioning sensorimotor and autonomic peripheral nervous system. What do we do when those peripheral systems aren't working? Today, we're speaking with Dr. Noah Kolb, guest editor of our latest issue of Continuum on peripheral nerve and motor neuron disorders. Dr. Jones: This is Dr. Lyell Jones, Editor-in-Chief of Continuum. Thank you for listening to Continuum Audio. Be sure to visit the links in the episode notes for information about subscribing to the journal, listening to verbatim recordings of the articles, and exclusive access to interviews not featured on the podcast. Dr. Jones: This is Dr. Lyell Jones, Editor-in-Chief of Continuum: Lifelong Learning in Neurology. Today, I'm interviewing Dr. Noah Kolb, who is Continuum's guest editor for our latest issue on peripheral nerve and motor neuron disorders. Dr. Kolb is a professor of neurology at the University of Vermont Larner College of Medicine in Burlington, Vermont, where he specializes in the care of patients with neuromuscular disorders, including patients with peripheral neuropathy and other immune-mediated neuromuscular diseases. Dr. Kolb, welcome. Thank you for joining us today. Why don't you introduce yourself to our listeners? Dr. Kolb: Well, thank you very much for having me. Please call me Noah. I've been a longtime listener of Continuum, dating all the way back to when they came on CDs, so it's really a pleasure to be here. Like you said, I'm a neuromuscular doctor up in Vermont. I take care of the whole scope of neuromuscular disease, but kind of wear 3 different hats. I focus my research primarily in chemotherapy-induced neuropathy, but also do other diseases as well. Obviously, see patients clinically, and then I'm an educator as well, so I run the neurology clerkship and the acting AIs for the medical school. So, it's a fun job. Dr. Jones: Well, thanks for sharing that little bit of history on Continuum Audio, Noah. I got to be honest with you, I don't know if I've ever seen a Continuum Audio CD. If anybody out there in the audience has a Continuum Audio CD, post a picture online and we'll like and share it. I wonder how many of those are still out there. I really appreciate you not just joining us today, Noah, but also putting together this really stellar issue, a very timely update and overview of peripheral nerve and motor neuron disorders. A lot of good topics for us to dig into today. What I'm going to do before we get into questions is ask our audience Continuum Audio's trivia question. Dr. Kolb and I were talking about this before we started recording here. So, the trivia question, just to frame it up a little bit, the transthyretin or TTR protein receives a lot of attention in neuromuscular medicine as the protein behind the most common causes of acquired and familial amyloidosis. But transthyretin is known in clinical settings by a different name and checked for an entirely different reason. So, the trivia question is, what is the other common name for transthyretin? Stick around, and we'll share the answer at the end of our interview. So, let's get right to it. Our listeners know that peripheral neuropathy is common, right? It affects 2 to 3 percent of the general population and 6 to 7 percent of patients who are older than 60. In your mind, Noah, what's the main thing you would like clinicians to know or do differently in the care of these patients? Dr. Kolb: Yeah, that's a great question. I think it's something that we spend a lot of time teaching our residents and working with our fellows about is understanding the right workup for people presenting with neuropathy because it's very easy to overdo it with more labs and a broader workup than you need. So, when somebody presents with sort of a garden variety neuropathy that doesn't have red flags, the important things to order in terms of a workup are hemoglobin A1C, B12, and SPEP with IFE, potentially serum light chains, and some thyroid studies as well. Because those are really the most common reasons, and then to make sure that they ask the most important historical questions, like about alcohol use, et cetera. If you're going to find a cause for neuropathy, particularly if it's slowly progressive and sensory predominant, oftentimes the answer is found right in that basic workup. Dr. Jones: Got it. And I think that's very well taken. And I think one of the questions that commonly comes up in the neuromuscular, but also in the broader neurology setting is, when you're evaluating a patient, especially an older patient who has a new onset length-dependent sensorimotor peripheral neuropathy, you've identified the neuropathy, and you're starting to consider what are those potential underlying disorders or risk factors that that neuropathy could be a warning sign of, right? So, you look for metabolic disease, B12 deficiency, paraproteinemia, et cetera. Where do you stop? In what settings do you do more expanded evaluations, genetic testing, et cetera? Dr. Kolb: Yeah, and I think this kind of goes back a little bit to the last question where the primary focus of the workup that we do is driven by the most common causes. That's why hemoglobin A1C is so important. And so, thinking through what is likely to be the cause in the specific patient setting is kind of really critical. And again, if you don't have red flags, then the labs that we mentioned previously are probably sufficient in terms of a workup. But if there are any of the other red flags, it's really important specifically because there may be treatable causes of neuropathy or things that would affect the prognosis that'd be important to understand earlier so we can make sure we either engage the right therapies or do a broader diagnostic workup. An important part of that is understanding when to use EMG nerve conduction studies and when not to. So obviously, as a neuromuscular doc who does EMGs, I'm very fond of them. But we regularly see patients in our lab who perhaps don't need one. If somebody has a sensory predominant, slowly progressive neuropathy, particularly if you have an etiology, those patients usually don't need an EMG nerve conduction study. When it's asymmetric, when there's prominent weakness, when there's a lot of autonomic symptoms, those are the times when it can be a lot more informative and helpful to try to get an EMG nerve conduction study to see if we can get at what the underlying etiology is. Dr. Jones: That's very helpful, Noah. Thank you. And so, let's think about a scenario that I think many of our listeners may have encountered in their practice. You're seeing a patient who has a somewhat rapidly progressive, painful neuropathy, which has some small fiber characteristics. They've got a little bit of autonomic dysfunction, and you worry about the possibility of amyloidosis. How do you approach that evaluation and treatment, and why is it important to think about that diagnosis? Dr. Kolb: Yeah, that's great. It's important to think about that diagnosis because we now have good treatments for AL amyloid and for ATTR-based amyloid. So, because these are treatable disorders, it's really critical that you identify them. And the reality is it's not always straightforward making a diagnosis of amyloid. As you would with any other type of neuropathy, the workup is gonna begin with serum free light chains, SPEP, trying to see if there are any monoclonal gammopathies or elevation in light chains. But importantly, you need to think about what the next diagnostic steps are and understanding how likely those tests are to be abnormal in the setting of amyloid is important as well, because the easier to obtain tests don't have perfect sensitivity. So, once you've moved on kind of from the basic labs, we think about a fat aspirate or a skin biopsy to look and see if there's any evidence of amyloid. But if your clinical suspicion is high enough, it's important to move to a sural nerve biopsy and genetic testing. That's really the best way to confirm this diagnosis. Dr. Jones: Very helpful. And obviously, that's not just academic, as it might have been at one point. This is something that we now have good disease-modifying therapies for, which leads to another question that I think our listeners may encounter in their practice. When you think about all the available gene tests in panels and other genomic tools that we have to investigate patients, when do you do a broad genetic evaluation for patients with neuropathy? Dr. Kolb: Yeah, it's a good question. It depends partly on specifically what we're looking for. I think that as with many things in neurology, one of the reasons I got interested in it, and many people did, is we like doing detective work, and the history often lies in the examination and in our clinical history at the bedside. And for that reason, often just in getting the initial history with a patient, you start to get clues that there may be a hereditary component. Sometimes it's in the history where you're able to elicit a family history of disorder, and they may or may not know that the patient had neuropathy, but it may be that somebody walked funny later in life or somebody always complained of foot pain. Or it may simply be when a patient takes their shoes off, or in Vermont, they're wearing sandals, and you see that they have characteristic changes of a neuropathy that is much more longstanding than the patient even recognizes. That's often the case with some of these forms of hereditary neuropathy because sometimes they don't have a lot of pain. And so, you see those characteristic changes in the foot, and it cues you to the need for genetic testing. In my world where I see a lot of patients with chemotherapy-induced neuropathy, I also think about it in patients who seem to be specifically sensitive to neurotoxic agents, where they get a much worse neuropathy than you would expect with exposure to drug, and it's important to consider it in those times as well. Dr. Jones: That's a great framing. I appreciate the way you put that. One of the great points in the issue is that patients who have sensory findings out of proportion to their sensory complaints, a lot of times it's worth thinking about a familial or genetic mechanism and then digging a little more into that family history, right? Dr. Kolb: I agree. Dr. Jones: Yeah. So, let's think of a different scenario. I know you do a lot of work with immune-mediated acquired neuropathies, and we're fortunate now, obviously, we have a lot of immunotherapy tools for the treatment of patients with neuropathies like chronic inflammatory demyelinating polyradiculoneuropathy. When it comes to CIDP, Noah, what's your initial approach to immunotherapy? That's one question. And another is, how do you incorporate some of the newer agents like efgartigimod? What's the role of that drug, or when do you go to rituximab or rozanolixizumab? Walk us through your approach to that. Dr. Kolb: Yeah, so I think it depends a lot on what the clinical presentation looks like and kind of what the patient's preference is. In taking care of neuropathy patients for what's been quite a while now, you find that some patients have a differing comfort level with sort of the newer drugs like efgartigimod versus some of the therapies that have been around for years and years and are tried and true. So, we know, for instance, that plasmapheresis and IVIG work well. In certain cases, we use steroids because they can work well as well, but also have long-term toxicities that you want to be aware of. It's been really exciting to see that efgartigimod is a new therapy that's on the market, and it's been a really interesting space to be involved in, in neuromuscular medicine as some of these new disease-modifying therapies have come out. The trials for efgartigimod are really exciting, and it was very important to our field when efgartigimod became available. But there have been other trials that showed similar drugs weren't that effective, and there are many studies happening right now for complement inhibition with varying results. So, it's been sort of one of these hot topics in neuromuscular medicine, trying to see what these new therapies are and figuring out how to integrate them. I find that oftentimes with patients, we'll start with the tried and true therapies like IVIG or plasmapheresis, but don't hesitate to reach to efgartigimod, particularly if it's more convenient for the patient. I think the other important point to make, and this is addressed nicely throughout some of the manuscripts, is that there are specific instances where certain drugs are preferred. So, for instance, if you're seeing somebody with CIDP that has hard-to-treat symptoms, is not responding to the normal therapies that we use, it's important to think about whether they may have a paranodal form of CIDP, in which case we often reach for things like rituximab instead because it works better. Dr. Jones: Outstanding. And so, I think that speaks to the importance of phenotyping, right? As we learn more about these acquired immune-mediated neuropathies, we're splitting, right? We're finding that the mechanisms are different in the tools that we have, the treatments are going to be more tailored, and more personalized to the patient. I think that's a great takeaway from the issue. So, Noah, you're in a unique position here, right? You're a world-renowned neuromuscular expert, and you have just edited a bunch of articles on neuromuscular medicine, peripheral nerve, motor neuron disorders written by experts in their respective fields. So, you have this bird's eye view of the specialty up to the minute, what's the latest. When you think about the entire issue, what would you say is the one topic that our readers or listeners could go to, to close the most important education gap in neuromuscular medicine? Dr. Kolb: It's a great question. It's akin to asking who my favorite child is, of which is all of them, but I would say that when Amro Estino and Ben Becker submitted their manuscript on paraproteinemic neuropathies, after I read it, I wrote an email back to them just telling them how well I thought it was organized and that it really addressed an issue that constantly plagues trainees and practitioners, is how to deal with monoclonal gammopathies and paraproteinemic neuropathies. It's a nice example of what happens when you give smart people the creative space to organize something in a way that they think makes sense. I certainly learned about the topic reading that, and I think it'd be very high yield for people reading Continuum. Dr. Jones: Totally agree. It's a wonderful article among many great articles, and that is a persistent education gap. So, I would direct our listeners to that article as well. You know, one of the things that I think about, you're an educator, I'm a clinician educator myself, thinking about the really interesting world of neuromuscular medicine, right? I have a significant part of my practice is in neuromuscular medicine and EMG, and I enjoy that very much. What do you think about trainees who might be interested in neuromuscular medicine, and they want to focus in it or pursue it as a career? How should they approach it? What does the training landscape look like from your perspective? Dr. Kolb: Yeah, that's a great question and an important one. So, I think that the case to be made for neuromuscular medicine is strong. I talk with the residents and my medical students about this regularly, but I think it's hard to find a place in medicine where the field is evolving more rapidly than it is in neuromuscular medicine, which makes it sometimes hard to stay up to date with everything that's happening, but it also makes it really interesting. To have new medicines coming online for us to change the paradigm for the way we've been treating patients for years and years is very exciting, and I think that those changes are only going to grow. Part of the future of neuromuscular medicine really is going to be in better genetic testing and broader genetic therapies. When you think about hereditary neuropathy as an example, there are tons of emerging therapies that are in pre-clinical trials and some starting in clinical trials. And so, the future of neuromuscular medicine is going to be constantly evolving where we can now treat disorders that we couldn't treat before. I mean, the easiest example is SMA, where previously that was a universally fatal disease for infants, right? And now we have treatments that are very effective. And there are multiple diseases where we're starting to develop therapies like this, so it's really exciting. From a training perspective, there are lots of opportunities for residents as they approach fellowship. There are tons of great neuromuscular fellowships around the program. I would include UVM in there as well, where there's really a wide variety of neuromuscular things that you can learn. And it's a wide and varied field, so people are learning ultrasound, which has been an emerging part of neuromuscular medicine, EMG, electrodiagnostics, Botox, but then also treating autoimmune disorders, hereditary disorders. So, it's really quite a broad field, and you can really sort of super sub-specialize into different areas, which allows you to really focus if that's what you want to do. Dr. Jones: So now it's time for the answer to our Continuum Audio Trivia question. Just to remind our listeners, what is the other common name for transthyretin? We think about transthyretin a lot, as Noah mentioned, in terms of acquired and familial amyloidosis, but what is the other name for it? Dr. Kolb, do you want to give the answer to our audience? Dr. Kolb: That would be prealbumin. Dr. Jones: Prealbumin. Again, we talk about transthyretin all the time because of the neurologic and cardiac presentations of ATTR wild type and variant transthyretin amyloidosis. But the protein itself, in the non-pathologic setting, in the non-amyloid setting, is a stable tetramer. Its normal function is to transport thyroxine and vitamin A throughout the body, but it also has a relatively short half-life. And on electrophoretic gels, it segregates near the albumin band, and therefore, for a long time was just called prealbumin because it was near the albumin band. And because of that short half-life, it's used as a rough or loose marker of nutritional status. So, all those times when I was a medical student and a resident ordering prealbumin to assess nutritional status, I was really checking transthyretin, and I had no idea. Dr. Jones: All right. So, Dr. Kolb, I really want to thank you for joining us. Thank you for such an outstanding conversation about peripheral nerve and motor neuron disease in the latest issue of Continuum. I learned a lot reading this issue. I learned a lot in our conversation today. I hope our listeners did too. I'm really grateful for your hard work taking on this issue, which I think will come in handy not only to our more junior listeners and subscribers, but also, our more experienced listeners as well. Dr. Kolb: Thanks for the opportunity to chat with you. I'm excited for the public to see the Continuum manuscripts. I think there's a lot to learn, and it's an exciting issue. Dr. Jones: I agree. Again, today we've been speaking with Dr. Noah Kolb, guest editor of Continuum's most recent issue on peripheral nerve and motor neuron disorders. Please check it out, and thank you to our listeners for joining today. Dr. Monteith: This is Dr. Teshamae Monteith, Associate Editor of Continuum Audio. If you've enjoyed this episode, you'll love the journal, which is full of in-depth and clinically relevant information important for neurology practitioners. Use the link in the episode notes to learn more and subscribe. Thank you for listening to Continuum Audio.
Interview with Keith A. Choate, MD, PhD, author of Longitudinal Growth in Children with Epidermal Differentiation Disorders. Hosted by Adewole S. Adamson, MD, MPP. Related Content: Longitudinal Growth in Children With Epidermal Differentiation Disorders
Send us Fan MailScott and John freestyle some more "songs about murder."https://www.youtube.com/@narcissisticmusicdisorderJoin us on Facebook at NMD podcast group.nmdpodcast@gmail.com to contact us.Tell your friends!!Be sure to Like and Subscribe. Thanks for listening!
JAMA Dermatology Author Interviews: Covering research on the skin, its diseases, and their treatment
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From October 1, 2024: Robert Mahari, a joint JD-PhD candidate at the MIT Media Lab and Harvard Law School, joins Kevin Frazier, Assistant Professor at St. Thomas University College of Law and a Tarbell Fellow at Lawfare, to explain how increased use of AI agents may lead humans to form troublingly and even addictive relationships with artificial systems. Robert also shares the significance of his research on common uses of existing generative AI systems. This interview builds on Robert's recent piece in the MIT Tech Review, which he co-authored with Pat Pataranutaporn.To receive ad-free podcasts, become a Lawfare Material Supporter at www.patreon.com/lawfare. You can also support Lawfare by making a one-time donation at https://givebutter.com/lawfare-institute.Support this show http://supporter.acast.com/lawfare. Hosted on Acast. See acast.com/privacy for more information.
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I discuss the profound risks to the world order if the contagion of chaos and lawlessness are allowed to run unchecked.#WWIII #War #USA This episode was published on September 25, 2026 at 7:31am EDT. Book an astrology reading with me.See my latest episodes.Please add yourself to my contact list.Recent and related episodes:The Criminality of Darkness - Sept 24, 2026Chiron in Astrology: Wounding, past-life trauma, rejection and healing - Sept 22, 2026USA: From Hegemon to Global Villain and Pariah - Sept 14, 2026A Defining Characteristic of Darkness - Sept 11, 2026Ai Insanity Must be Stopped - Sept 10, 2026A Crisis of Stupidity - A Spiritual Dilemma - Aug 10, 2026What People Misunderstand About the Age of Aquarius - Aug 9, 2026How You Can Change Our World - Aug 8, 2026Welcome to the End of The Fossil Fuel Era - Aug 7, 2026Enshittification and Nanny State Idiocy - Nobody wants any of this! - July 14, 2026Stop Feeding The Beast - July 20, 2025Stupidity... or Sabotage? - July 23, 2025Pluto in Aquarius - Dawn of Global Consciousness - Feb 14, 2022Silence is Complicity - Sept 28, 2025AI and the Death of the Internet - Feb 1, 2024Why it's been so hard for Sagittarius: 2008-2026 - Oct 15, 2024
Renowned comparative political scientist and former CASBS fellow (1999-2000) David Laitin has influenced generations of scholars through his investigations of the intricate interplay of cultural phenomena – such as language, religion, and ethnicity – with politics and political life across societies. The complex dynamics he reveals get to the roots of conflict, cooperation, identity formation as well as nation- and state-building. Laitin takes us on a sweeping tour of some of his career's principal works, findings, and collaborations in conversation with 2025-26 CASBS fellow Olukunle Owolabi.DAVID LAITIN: Stanford faculty page | Google Scholar page | National Academy of Sciences bio | Wikipedia page | Johan Skytte Foundation article |OLUKUNLE OWOLABI: Villanova faculty page | CASBS bio | Villanova article on six awards won by Kunle's 2023 book |David Laitin books:D. Laitin. Politics, Language, and Thought: The Somali Experience (Univ. of Chicago Press, 1977).D. Laitin. Hegemony and Culture: The Politics of Religious Change among the Yoruba (Univ. Chicago Press, 1986).D. Laitin and S. Samatar, Somalia: Nation in Search of a State (Westview Press, 1987).D. Laitin. Language Repertoires and State Construction in Africa (Cambridge Univ. Press, 1992).D. Laitin. Identity in Formation: The Russian-speaking Populations in the Near Abroad (Cornell Univ. Press, 1998).D. Laitin. Nations, States and Violence (Oxford Univ. Press, 2007).D. Laitin, C. Adida and M. Valfort. Why Mulsim Integration Fails in Christian-heritage Societies (Harvard Univ. Press, 2016).D. Laitin and D. Christensen. African Politics since Independence: Order, Development and Democracy (Yale Univ. Press, 2019).David Laitin articles referenced in this episode:D. Laitin and R. Ramachandran, "The Historical Sources of Language Policy," Journal of Politics (2014).D. Laitin and R. Ramachandran, "Language Policy and Socioeconomic Outcomes," Palgrave Handbook of Economics and Language (2026).D. Laitin and R. Ramachandran, "Linguistic Diversity, Official Language Choice and Human Capital," Journal of Development Economics (2022).D. Laitin, R. Ramachandran and S. Walter," The Legacy of Colonial Language Policies and their Impact on Student Learning: Evidence from an Experimental Program in Cameroon," Economic Development and Cultural Change (2019).D. Laitin and R. Ramachandran, "Language Policy and Human Development," American Political Science Review (2016).D. Laitin, J. Hainmueller, et al., "Breaking Down Barriers to Naturalization for Low-income Immigrants: Evidence from a Randomized Controlled Design," Proceedings of the National Academy of Sciences (2018).D. Laitin, T. Gurr, et al., "Socially Relevant Ethnic Groups, Ethnic Structure and AMAR," Journal of Peace Research (2015).D. Laitin and J. Fearon, "Civil War Non-onsets: The Case of Japan," Journal of Civilization Studies (2014)D. Laitin, C. Adida and M. Valfort, "Identifying Barriers to Muslim Integration in France," Proceedings of the National Academy of Sciences (2010).D. Laitin and J. Fearon, "Sons-of-the-soil, Migrants, and Civil War," World Development (2011).D. Laitin and A. Krueger, "Kto-Kogo? A Cross-country Study of the Origins and Targets of Terrorism," in Terrorism, Economic Development, and Political Openness (Cambridge Univ. Press, 2008).D. Laitin and E. Berman, "Religion, Terrorism and Public Goods: Testing the Club Model," Journal of Public Economics (2008).D. Laitin and A. Krueger, "'Misunderestimating' Terrorism: The State Department's Big Mistake, Foreign Affairs (2004).D. Laitin and J. Fearon, "Neotrusteeship and the Problem of Weak States," International Security (2004).D. Laitin and J. Fearon, "Ethnicity, Insurgency, and Civil War," American Political Science Review (2003).D. Laitin and J. Fearon, "Violence and the Social Construction of Ethnic Identities," International Organization (2000).D. Laitin and J. Fearon, "Explaining Interethnic Cooperation," American Political Science Review (1996).D. Laitin, "The Tower of Babel as a Coordination Game: Political Linguistics in Ghana," American Political Science Review (1994).D. Laitin, S. Kalyvas and C Sole, "Language and the Construction of States: The Case of Catalonia in Spain," Politics and Society (1994).D. Laitin, "Linguistic Conflict in Catalonia," Language Problems and Language Planning (1987).David Laitin's full curriculum vitae accessible from his Stanford University faculty page.PostscriptIn the episode, David Laitin acknowledges the influence of two towering social scientists -- Clifford Geertz and Albert Hirschman -- both of whom were CASBS fellows (Geertz in 1958-59, Hirschman in 1968-69). Hirschman, notably, wrote the seminal book Exit, Voice, and Loyalty: Responses to Decline in Firms, Organizations, and States while at CASBS. In this podcast episode, David Laitin describes developing the argument for his book Identity in Formation by following the conceptual framework of the classic Hirschman book. Center for Advanced Study in the Behavioral Sciences (CASBS) at Stanford UniversityExplore CASBS: website | Bluesky | X | YouTube |LinkedIn | podcast | latest newsletter | signup | outreachHuman CenteredProducer: Mike Gaetani | Audio engineer & co-producer: Joe Monzel
In this episode, Dr Tsen Vei Lim talks to Dr Martine Skumlien and Professor Valentina Lorenzetti. Martine is a research fellow at King's College London in the UK and Valentina is a professor at the Australian Catholic University in Australia. The interview covers Martine and Valentina's research article on brain reward function in young people with cannabis use disorder.The idea that the brain reward system is affected in people with cannabis use disorder [01:28]How our understanding of the neuroscience behind cannabis use disorder affects how we treat cannabis use disorder [03:46]The novel contribution of Martine and Valentina's study [06:06]How Martine and Valentina investigated the brain reward system in cannabis use disorder [08:18]The key findings from the study [09:24]How we think about the neuroscience of cannabis use disorder [12:33]How do we make sense of the findings alongside the current evidence base [14:33]How the findings sit in the theory of addiction as a brain disease [19:50]The wider implications on future treatment of cannabis use disorder [21:55]About Tsen Vei Lim: Tsen Vei is an academic fellow supported by the Society for the Study of Addiction, currently based at the Department of Psychiatry at the University of Cambridge. His research integrates computational modelling, experimental psychology, and neuroimaging to understand the neuropsychological basis of addictive behaviours. He holds a PhD in Psychiatry from the University of Cambridge (UK) and a BSc in Psychology from the University of Bath (UK). About Martine Skumlien: Martine is a Research Fellow at the King's College London Social, Genetic & Developmental Psychiatry Centre. Her work focuses on cannabis harm reduction, policy, and impact on the brain. She was previously a research associate in the National Institutes for Health and Care Research (NIHR) Policy Research Unit in Addictions where she conducted research to inform policy within the drug and addictions field, and at the University of Bath where she carried out mixed-methods research into drug checking and detection of novel psychoactive substances. She earned her PhD from the University of Cambridge, investigating how cannabis use influences motivation and reward processing in the brain.About Valentina Lorenzetti: Valentina is a professor, founding Lead of the Neuroscience of Addiction & Mental Health Program, and co-founding Deputy Director of the Healthy Brain and Mind Research Centre at the Australian Catholic University in Melbourne Australia. She also serves as Senior Editor of the journal Addiction. Valentina has dedicated her career to understanding the neurobiology behind how people move into, and out of, addiction and entrenched mental health problems, across Australia, the UK, and Brazil, with a consistent focus on identifying with precision the core neurocircuitry affected and translating that understanding into effective intervention. Valentina's program combines advanced multimodal neuroimaging, neuromodulation tools, global multi-site cohorts, and novel interventions such as cannabidiol, craving management strategies, and neurofeedback. Tsen Vei, Martine and Valentina have no conflicts of interest to declare.Original article: Brain reward function in young people with cannabis use disorder: A functional magnetic resonance imaging study https://doi.org/10.1111/add.70492 The opinions expressed in this podcast reflect the views of the host and interviewees and do not necessarily represent the opinions or official positions of the SSA or Addiction journal.The SSA does not endorse or guarantee the accuracy of the information in external sources or links and accepts no responsibility or liability for any consequences arising from the use of such information.Music provided by Jack Shakespeare. Hosted on Acast. See acast.com/privacy for more information.
Recorded 2026-09-24 02:00:43
A round-up of the main headlines in Sweden on the 24th September 2026. You can hear more reports on our homepage www.radiosweden.se, or in the app Sveriges Radio. Lyssna på alla avsnitt i Sveriges Radios app. Presenter/producer: Kris Boswell.
In this conversation, Dr. Marie Feuer speaks with Alexis Kur—a high school special education teacher, mental health advocate, speaker, and person living with Dissociative Identity Disorder—about the many parts of being human.They explore Dissociative Identity Disorder, the usefulness and limitations of diagnosis, and how labels can sometimes help us understand our experiences without defining who we are. They also discuss special education, trauma, identity, advocacy, and what it means to live differently in a world that often pathologizes difference.ABOUT ALEXIS KURAlexis is a high school special education teacher, mental health advocate, speaker, and founder of Permission to Define. After 15 years in a successful environmental consulting career, she chose to redefine success and pursue work centered on education, advocacy, and human connection.Today, Alexis works with teenage boys in high school special education while using her professional and lived experience to challenge stigma surrounding trauma, Dissociative Identity Disorder, disability, and identity.Her work is grounded in a simple belief: people should never be reduced to a diagnosis, a label, or someone else's definition of who they are allowed to become.LEARN MORE OR INVITE ALEXIS TO SPEAKPermission to Define:https://permissiontodefine.com/HEALING HEARTS THERAPEUTIC FARMWebsite:https://healingheartsthera51.wixsite.com/healingheartstherapeFacebook:https://www.facebook.com/people/Healing-Hearts-Therapeutic-Farm/100043854923604/Donate through Venmo:https://account.venmo.com/u/HHTF1Venmo handle: @HHTF1CONVERSATIONS WITH DR. MARIELiving differently in a world that isn't working.Conversations across education, psychology, spirituality, and health.WORK WITH DR. MARIEDr. Marie Feuer holds a PhD in Health Psychology and has practiced psychic and energy work since 1975. She offers private one-on-one sessions beginning with a free 30-minute introductory Zoom conversation.https://DrMarie.orgSTAY CONNECTED WITH DR. MARIEReceive new conversations, articles, and occasional updates from Dr. Marie.Join the email list:http://eepurl.com/i9Q4zgDISCLAIMERThis conversation is provided for educational and informational purposes only. It is not medical, psychological, or mental health advice and is not a substitute for care from a qualified professional.
Cameron Turtle, CEO of Waltham, Mass.-based Spyre Therapeutics, on developing long-lasting antibodies for immune disorders.
Can uncertainty make you stronger and does Antifragile actually show you how?In this Mere Mortals Book Review, Juan explores Antifragile: Things That Gain from Disorder by Nassim Nicholas Taleb. There are powerful ideas here, but I finished the book with mixed feelings about its practical application, repetition and relentless personal attacks.I unpack the difference between fragile, robust and antifragile, explore the barbell strategy and question how easily these frameworks translate into everyday life.My biggest takeaway? Via negativa: improving by removing harmful habits and unnecessary complexity. Sometimes progress comes from subtraction.We also explore why a system can benefit from failures that hurt its individual members, my pushback on Taleb's views about technology, and the ethics of becoming stronger at someone else's expense.Glad I read it, but would I recommend reading every page?CHAPTERS00:00 Introducing Antifragile and Taleb01:30 Why I picked it up02:08 Structure, maths and optional chapters03:23 Fragile vs robust vs antifragile04:51 The limits of antifragility06:25 The Hydra, aviation and individual sacrifice08:58 Longevity and Taleb's confrontational style10:45 Where I push back on health and nature12:00 The barbell strategy: can you apply it?13:49 Convexity, concavity and practical usefulness16:06 Via negativa: improvement through subtraction17:04 The Lindy effect, technology and AI18:34 Too long, too repetitive, too many attacks?19:43 The ethics of shifting risk onto others20:51 My verdict: should you read it?21:40 What I'll apply to my own lifeWhat's one thing you could REMOVE from your life to make it better? Let me know in the comments.Subscribe to Mere Mortals Book Reviews for honest reflections on books, big ideas and their place in everyday life.Connect with Mere Mortals:Website: https://www.meremortalspodcast.com/Discord: https://discord.gg/jjfq9eGReUTwitter/X: https://twitter.com/meremortalspodsInstagram: https://www.instagram.com/meremortalspodcasts/TikTok: https://www.tiktok.com/@meremortalspodcast Connect with Mere Mortals:Website: https://www.meremortalspodcasts.com/Discord: https://discord.gg/Xs9DjsurFqTwitter/X: https://twitter.com/meremortalspodsInstagram: https://www.instagram.com/meremortalspodcasts/TikTok: https://www.tiktok.com/@meremortalspodcastsValue 4 Value Support:Website: https://www.meremortalspodcasts.com/supportPaypal: https://www.paypal.com/paypalme/meremortalspodcast
The American author argues in her The Atlantic cover story "Empire of Grift" that Donald Trump and his circle have revolutionized U.S. foreign policy for private gain. Some of it is ideological. Much of it is driven by self-interest. Anne Applebaum says Canada is right to adapt. And she wonders if America understands what it has become.
Interview with Laura Fässler, MSc, author of Psychological Interventions Targeting Auditory Hallucinations in Persons With Psychotic Disorders: A Systematic Review and Meta-Analysis. Hosted by John Torous, MD. Related Content: Psychological Interventions Targeting Auditory Hallucinations in Persons With Psychotic Disorders
(Throwback | Originally Aired 9/9/2019) Neely Fuller discusses the existence of racism with a nonwhite caller. Caller does not except or the acknowledge the existence of racism. Dr. Frances Cress Welsing speaks about a code of Black Self Respect. Racism Avoidance Disorder(RAD) & The Industry Of Black American Confusion https://youtu.be/lF0gWadJBPs?si=sZEQcv9uz-C4cZxh #fba #producejustice #vgq #neelyfullerjr #thecodeistheleader #rad #racism #rws #par #peopleactivityradio #francescresswelsing #lgbtq
Interview with Laura Fässler, MSc, author of Psychological Interventions Targeting Auditory Hallucinations in Persons With Psychotic Disorders: A Systematic Review and Meta-Analysis. Hosted by John Torous, MD. Related Content: Psychological Interventions Targeting Auditory Hallucinations in Persons With Psychotic Disorders
In this episode, learn insights from Dr. Jenn Rapkin a naturopathic physician, bodyworker, former dancer, and Frequent Feeler with more than 25 years of experience in mind-body and body-centered therapies. Her new book The Feeling Muscle chronicles her personal and professional transformation from physician to a shepherd of “feelings.” In her clinical practice, her bodywork table is a place to hold space for, validate, and give voice to her patients' inner felt emotion. ✔️Purchase The Emotional Detox 50 Card Deck
In this episode of Autistic Standpoint Theory, Isha Snow is joined by autistic advocate and technology professional Sam Farmer to explore what happens when autistic people are expected to navigate systems built around different ways of communicating, learning and relating to the world.Drawing on Sam's career in technology and his experience as an autistic self-advocate, they discuss neurodiversity-affirming support, accommodations and the importance of involving autistic people in the development of tools and services intended for their community.Together, Isha and Sam consider the enormous diversity within autism, why support needs aren't always visible, and whether some of what is described as autistic deficit might instead emerge from a mismatch between autistic people and the environments around them.The conversation also turns to empathy, advocacy and Sam's opposition to aversive interventions, asking what our institutions could look like if autistic knowledge was treated as expertise rather than an afterthought.Autistic Standpoint Theory is part of the Autistic Culture Podcast Network.
If you have a vestibular disorder, there’s a good chance your thyroid is part of the story. You know I love bringing in other qualified professionals to dig deeper on these more nuanced topics, so for this conversation we have Registered Dietitian and fellow Hashimoto’s patient, Alisha Knicely! She breaks down all things thyroid—what Hashimoto’s is, how it’s different from hypothyroidism, what optimal labs look like, how gut health and leaky gut are connected to autoimmune conditions, and what you can do about all of this. We also touch on gluten, dairy, mold, and water quality. You're going to want to bookmark this one because it's jam packed! In this episode, we'll dig into: How Alisha became a Hashimoto’s patient turned registered dietitian Hyperthyroidism vs. hypothyroidism What's included in a full thyroid panel How to understand optimal vs. conventional lab ranges When to consider medication How thyroid hormones impact every single cell in the body Chronic vs. acute inflammation Practical, sustainable steps to lower inflammation naturally The elimination diet and reintroduction approach The best way to address leaky gut Why you should consider the GI Map stool test Why water quality matters especially for thyroid patients Alisha's personal mold story and how she cleared her mycotoxin levels Air quality, infrared sauna, and other mold detox resources Whether it’s your thyroid, your gut, your water, or the air you’re breathing, the root causes are addressable and you don’t have to figure it out alone. Related Episodes: Ep 91 Mold & Dizziness: https://thevertigodoctor.com/podcast/91-mold-dizziness-what-you-need-to-know/ Meet: Alisha Knicely, RD Alisha Knicely is a Registered Dietitian, certified in Integrative and Functional Medicine, and a fellow Hashimoto’s patient of nearly a decade. Her own experience navigating an autoimmune thyroid diagnosis (and not getting the answers she needed) led her to specialize in thyroid and hormonal health. She helps clients get to the root of their Hashimoto’s through nutrition, gut health, lifestyle and functional testing so they can finally start feeling like themselves again. Connect w/ Alisha Knicely: Instagram: https://www.instagram.com/lisha_thyroid_rd/ TikTok: https://www.tiktok.com/@lisha_thyroid_rd Links Mentioned: Vestibular Group Fit (code GROUNDED at checkout for 15% off!): https://thevertigodoctor.com/vestibular-group-fit (which is where you'll find the Histamine Webinar with Isabel Smith where we talked water filters) Alisha's Instagram post on optimal labwork mentioned: https://www.instagram.com/p/Dbqf3TqjoAD/ Dr. Jill Crista's mold detox resource: https://drcrista.com/ Free Resources: The 4 Steps to Managing Vestibular Migraine: https://thevertigodoctor.myflodesk.com/cb5js0y78n The PPPD Management Masterclass: https://thevertigodoctor.myflodesk.com/new-pppd What your Partner Should Know About Living with Dizziness: https://thevertigodoctor.myflodesk.com/partnership The FREE Mini VGFit Workout: https://thevertigodoctor.myflodesk.com/minifit The FREE POTS – safe Workouts: https://thevertigodoctor.myflodesk.com/pots Connect with Dr. Madison (@TheVertigoDoctor): https://instagram.com/thevertigodoctor Work with Dr. Madison: For 1:1 Vestibular Rehabilitation Therapy, email madison@thevertigodoctor.com Otherwise, I'll see ya in Vestibular Group Fit! Connect with Dr. Jenna (@dizzy.rehab.therapist): https://www.instagram.com/dizzy.rehab.therapist/ Learn about the Oak Method: http://thevertigodoctor.com/why-vestibular-group-fit Love what you heard?Consider leaving a review on your favorite podcast platform to help us reach more vestibular warriors like you! This podcast is for informational purposes only and may not be the best fit for you and your personal situation. It shall not be construed as medical advice. The information and education provided here is not intended or implied to supplement or replace professional medical treatment, advice, and/or diagnosis. Always check with your own physician or medical professional before trying or implementing any information read here. hashimoto’s and gut health, integrative functional medicine, autoimmune thyroid condition, thyroid dietitian, graves disease, vestibular migraine, chronic dizziness, hormone health, gut issues, lifestyle changes, optimal lab values, migraine management
Abandonment of prescribed buprenorphine for opioid use disorder, 2020-2024 JAMA Network Open This retrospective cohort study examined characteristics associated with abandonment of newly prescribed buprenorphine, defined as a prescription that was written but not dispensed or filled, and trends in abandonment among adults from 2020 to 2024 to inform efforts to improve buprenorphine access. Researchers found the proportion of abandoned newly prescribed buprenorphine prescriptions for opioid use disorder increased from 2020 to 2024. Over 1 in 3 patients' first buprenorphine prescriptions were abandoned in 2024, representing a missed opportunity for treatment initiation and engagement. Hispanic patients had a higher proportion of prescription abandonment, possibly due to language and pharmacy-level barriers, such as limited retail pharmacies in Hispanic communities and neighborhoods. Increasing opioid overdose death rates among Hispanics highlights the importance of expanding access among this population. Read this issue of the ASAM Weekly Subscribe to the ASAM Weekly Visit ASAM
Remethylation disorders are clinical chameleons, presenting with neurological, psychiatric, ophthalmological, renal or multisystem disease. Professor Martina Huemer joins the JIMD Podcast to discuss the revised international guidelines, including when to measure total homocysteine, newborn screening and the move towards high-dose hydroxocobalamin. She also explains why shared treatment protocols are needed to strengthen the evidence behind future recommendations. First Revision of the Guidelines for the Diagnosis and Management of Remethylation Disorders Giorgia Olivieri et al. https://doi.org/10.1002/jimd.70177
Body dysmorphic disorder (BDD) is more than dissatisfaction with appearance. It can involve an intense fixation on perceived flaws that others may barely notice, leading to anxiety, social withdrawal, repeated reassurance-seeking, and a diminished quality of life. Gerianne DiPiano and psychologist and sex therapist Dr. Juliana Hauser discuss the symptoms and possible contributing factors behind BDD, including social media, cultural beauty standards, pregnancy, aging, perimenopause, and menopause. They also examine the important distinction between ordinary appearance concerns and the persistent preoccupation associated with body dysmorphic disorder, including why cosmetic procedures may not resolve the underlying distress. The conversation highlights warning signs to recognize in yourself or someone you love, the importance of compassionate support without judgment, and treatment options such as cognitive behavioral therapy and professional mental health care.To connect with Dr. Juliana Hauser visit https://dr-juliana.com/ For more information on women's health advocacy, visit the FemmePharma website www.femmepharma.com
Darker days and less sunlight can take a toll on your health. We talk with a health expert and get some simple tips on what you can do to combat Seasonal Affective Disorder.
What if the story you've been telling yourself isn't actually true?For years, Shannon was convinced she was the exception and that her anxiety was different, that she'd tried everything and nothing was ever going to work, and that panic and agoraphobia were just going to be part of her life forever. Sound familiar? In this episode, Shannon breaks down why "what if I can't recover" is a story anxiety loves to create, how that story quietly shapes everything you do (and don't do), and why your anxiety isn't as "special" or "different" as it feels.She also shares real messages from past Panic to Peace students who spent years believing recovery wasn't possible for them and are now back to driving, traveling, and living lives they once thought were completely out of reach.If you've ever thought "I've tried it all and nothing works," this episode is your permission to ask a different question: not what if I can't, but what if I can?P.S. Panic to Peace opens September 22nd and starts October 4th: 10 weeks, live, with Shannon every step of the way. If you've been on the fence for months (or years), this is your sign.PANIC TO PEACE STARTS OCTOBER 2026. GET ON THE WAITLIST HERE: https://www.ahealthypush.com/live-panic-to-peaceA HEALTHY PUSH INSTAGRAM: https://www.instagram.com/ahealthypush/GET THIS EPISODE'S SHOW NOTES: https://www.ahealthypush.com/post/whatif
(Throwback | Originally Aired 9/9/2019) Neely Fuller discusses the existence of racism with a nonwhite caller. Caller does not except or the acknowledge the existence of racism in contemporary times. Racism Avoidance Disorder(RAD) & The Industry Of Black American Confusion https://youtu.be/lF0gWadJBPs?si=sZEQcv9uz-C4cZxh #fba #producejustice #vgq #neelyfullerjr #thecodeistheleader #rad #racism #rws #par #peopleactivityradio
Gut Check: Andrea Shin, MD, on Rome V Updates for Bowel DIsorders by Gastroenterology Learning Network
Send us Fan MailEvery single convo I've ever had with a wife has had this ONE thing in common even though nearly every situation was unique. And it's this key that unlocks what God wants to do in and through your marriage. Support the showChelsey Holm | the Wife Coach "I lead Christian wives to become TENDER, TENACIOUS & TAKING BACK TERRITORY the enemy has stolen. To live by God's design in marriage through right order, repentance & radical obedience.First step? Grab the 30 Day Guide: War Room RESET: daily action to regulate, realign, and reconnect.
Mast cell disorders can feel confusing, especially with so much information floating around online and on social media. In this episode, we cut to the chase and tackle the most common mast cell disorder FAQs, straight from the community. Dr. Dareen Siri joins us to work through community questions on mast cell disorders one by one, from what a mast cell actually is to testing, treatment, diet, and long-term outlook. What we cover in this episode about mast cell disorders What is a mast cell. Dr. Siri breaks down what mast cells do in the body and why an overactive one causes symptoms. The different mast cell disorders. Allergies, autoimmune activation, and clonal disorders like indolent systemic mastocytosis each work differently. Which tests actually matter. Blood tests, the KIT D816V mutation test, and when a bone marrow biopsy comes into play. Plus, should you consider a urine test? Treatment and long-term outlook. What targeted treatment (avapritinib) looks like now, and whether a mast cell disorder shortens your lifespan. Diet, supplements, and bone health. Whether a low-histamine diet helps, what the evidence says about supplements, and why bone density matters long term. More resources about mast cell diseases All of our mast cell disease episodes About the PIONEER Trial for Avapritinib Mast Cell Disease Toolkit Mental Health and Mast Cell Disorders Symptoms, Diagnosis & Treatment Options for Mast Cell Disorders (Recording) ************ Made in partnership with The Allergy & Asthma Network. Thanks to Blueprint Medicines for sponsoring today's episode. This podcast is for informational purposes only and does not substitute for professional medical advice. Always consult with your healthcare provider for any medical concerns.
Join Beth Krone, Ph.D., to learn about the growing body of scientific evidence suggests that ADHD is associated with inflammatory and immune system conditions, from asthma to food or skin allergies, and how to present a clear picture to medical providers. Resources: Inflammatory Disorders and ADHD Free Download: Free Guide to Health & Fitness: Lifestyle Changes for Adults with ADHD Read: ADHD's Curious Connections to Chronic Inflammation and Dysautonomia Read: Bendy Bodies, ADHD Brains: Connecting the Dots Read: Hypermobility Often Misdiagnosed as Mental Illness: New Study Access the video and slides for podcast episode #620 here: https://www.additudemag.com/webinar/inflammatory-disorders-adhd-immune-system/ Thank you for listening to ADDitude's ADHD Experts podcast. Please consider subscribing to the magazine (additu.de/subscribe) to support our mission of providing ADHD education and support.
Unpack the myths, realities, and clinical considerations surrounding pediatric concussions with an interprofessional team from The University of Tulsa's Concussion Center.Guests: Laura Wilson, PhD, CCC-SLP, CBIST; Rachel Hildebrand, PhD, LAT/ATC, CBIS; and Jennifer Steward, PhDEarn 0.10 ASHA CEUs for this episode with Speech Therapy PDWatch on YouTubeIn this episode of First Bite, Michelle Dawson, MS, CCC-SLP, CLC, BCS-S, FNAP, is joined by an interprofessional team from The University of Tulsa's Concussion Center. Together, they explore common misconceptions about concussions, including how symptoms present differently across toddlers, children, and adolescents, and why recognizing these differences is critical for timely identification and care. The conversation also highlights important topics such as second impact syndrome, current best practices in concussion management, and the role of interprofessional collaboration in supporting recovery.About the Guest(s): Laura Wilson, PhD, CCC-SLP, CBIST, is an Associate Professor in Communication Sciences & Disorders at The University of Tulsa. She is a Co-Director of the Concussion Center and a Certified Brain Injury Specialist Trainer. Her clinical and research interest is acquired brain injuries, with a specific focus on concussion. Rachel Hildebrand, PhD, LAT/ATC, CBIS is a Clinical Associate Professor of Athletic Training at The University of Tulsa. She is the co-Director of the Concussion Center at The University of Tulsa. Her research has highly focused on interdisciplinary concussion management, specifically for those experiencing prolonged concussion recovery. Jennifer Steward, Ph.D., is a clinical psychologist and an Applied Associate Professor of Psychology at The University of Tulsa. She has been a member of the concussion team since the Concussion Center's opening, and supervises advanced clinical psychology doctoral students in their work as part of the interdisciplinary team. Show Notes:University of Tulsa Concussion CenterHeads Up CDCHEADS UP to Schools: Online Concussion Training Pedsconcussion.comConcussioninsportgroup.comLove Money: Support The University of Tulsa
Is it possible to follow a diet that's both vegan and keto? And can a diet like that be used as part of a care plan for bipolar disorder? In this episode of Metabolic Mind, Dr. Bret Scher speaks with author and advocate Dyane Harwood about how she uses a vegan ketogenic diet as part of her treatment for postpartum bipolar disorder.Dyane shares how she first discovered vegan keto, why she started tracking ketones and net carbs, and what she eats in a typical day, from her vegan keto smoothie to tofu, avocado, nut butter, and carefully chosen supplements. She also discusses the practical challenges of vegan keto, including protein intake, B12, omega-3s, magnesium, vitamin D3, eating out, social pressure, and finding a clinical team that understands metabolic psychiatry.They cover:How Dyane discovered vegan keto for bipolar disorderWhy ketosis became more important to her than dietary labelsWhat a typical vegan keto day looks likeHow changing her protein intake affected her ketone levelsWhy tracking net carbs, glucose, and ketones helped her personalize the dietThe supplements she uses, including B12, DHA/EPA, magnesium, vitamin D3, and acetyl-L-carnitineWhat Dyane reports about changes in her energy, activity level, cravings, and moodWhy support, resources, and mentorship can make the process easierHow she thinks about progress, flexibility, and improving over timeDyane's experience offers a personal example of how a vegan ketogenic diet can fit within a broader treatment plan. Her approach is practical and grounded in the idea that progress can start before everything feels perfect.
Tickets for Dopeycon: https://buytickets.at/thedopeyfoundation/2216905PAtreon: www.patreon.com/dopeypodcastEpisode summaryTHIS WEEK ON DOPEY! Actor, comedian, director and Curb Your Enthusiasm star Jeff Garlin joins Dopey for an unusually candid conversation about comedy, compulsive eating, mental illness, addiction and the breakdown that nearly killed him.Jeff explains why he believes his morally questionable Curb character is nothing like the person he tries to be. He talks about gratitude, refusing to indulge in self-pity and the early comedy lesson that taught him never to make an audience feel sorry for him.The conversation then moves into Jeff's lifelong relationship with food. He describes compulsively eating sugar as a child, hiding food, binging on the road and eventually developing diabetes. Even a stroke and the loss of part of his toe couldn't make him stop. Although alcohol and marijuana were also part of his story, Jeff says food was the addiction that brought him to his knees.Jeff opens up about working on The Goldbergs while struggling with undiagnosed bipolar disorder, severe ADHD, resentment and increasingly erratic behavior. After his departure from the show became public, shame and fear pushed him toward suicide. He called two people and told them that he intended to be dead by noon. His family and friends intervened, and Jeff entered treatment in Cincinnati, where DBT helped him understand his emotions and behavior. After returning home, a friend brought him to an AA meeting and gave him the beginning of a new life.Jeff also discusses transcendental meditation, clairvoyant experiences, his friendship with Larry David and how a lunch conversation became the original HBO special that evolved into Curb Your Enthusiasm. He reflects on the show's improvisational process, Bill Buckner's redemptive appearance and the extraordinary creative mind of Larry David.Before the interview, Dave shares listener stories involving grief, Suboxone, meth, crack, a police raid, cocaine psychosis, boofing drugs and leading a recovery meeting while hallucinating animals underneath the bed.PLUS MORE! ON A BRAND NEW EXCITING EPISODE OF YE GOODE OLDE DOPEY SHOW... Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
In this season 8 opener Rosy shares both her experience recovering from bipolar disorder and the heartbreak of watching her beloved son begin to show signs of an even more extreme form of bipolar disorder called schizoaffective disorder. This is a story in parallel, two lives deeply intertwined, yet also slowly tearing apart as her son's illness became increasingly severe.Support the showElemental Psychedelicshttps://www.elementalpsychedelics.com/Explore every episode through themes, domains, formats, and speakers. The BFTA CODEX is a listener-built and curated field guide to the podcast. https://bfta-codex.orgBFTA episode recommendations/Podcast pagehttps://www.craigheacockmd.com/podcast-page/BFTA on IG @backfromtheabysspodcasthttps://www.instagram.com/backfromtheabysspodcast/Support the show
Journalist Matt Gutman hid his panic attacks for twenty years—until one hit him live on air. Tami asks him which of the psychedelics he tried actually changed things. His answer takes us to a mat in Peru's Sacred Valley, through something like ego death, and into a scream he didn't know he'd been holding. Find the complete interview, "Conquering a Lifetime of Panic Attacks," here: https://bit.ly/matt-gutmanSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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