Medical condition in which excess body fat harms health
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Today we cover injuries, overtraining, proper form, obesity, and much much more!All Links: https://swolenormous.com
Resources for the Community:___________________________________________________________________Linktree Our Favorite ThingsNeed help appealing your GLP-1 dials? www.FindHonestCare.com/KimFind Your US Representatives https://www.usa.gov/elected-officials ______________________________________________________________________Will Medicare finally expand access to GLP-1 medications for obesity? How do you qualify? In this episode, Kim and Kat are joined by community co-host Deb Cooperman and DeeDee, a 70-year-old GLP-1 patient, to discuss Medicare coverage, weight loss, maintenance, and life on GLP-1s after 60.Deb shares her experience paying cash for treatment while hoping to qualify for the new Medicare Bridge Program. DeeDee discusses maintaining her weight loss after losing access to medication, moving to compounded treatment, and growing up in a generation shaped by diet culture.Topics include:• GLP-1 medications after 60• Weight loss and maintenance• Medicare coverage and affordability• Diet culture and obesity• Long-term patient tips and lessons learned• Access to obesity treatmentObesity medicine specialist Dr. Michael Albert joins the conversation to answer common questions about Medicare coverage and the new Medicare Bridge Program, including:• Who qualifies• How the program works• How to apply• Options if you don't qualifyHe also discusses:• Weight loss with GLP-1s in older adults• Protecting muscle mass and prioritizing protein• Side effects to watch for• What to advocate for with your doctorWhether you're on Medicare, approaching eligibility, or helping a loved one navigate obesity treatment, this episode offers practical advice, patient perspectives, and expert guidance.Follow Guests Follow Deb https://www.instagram.com/thedebcooperman https://www.instagram.com/thedebcooperman Follow Dee DeeTikTok https://www.tiktok.com/@deesback Dr. Michael AlbertInstagram and TikTok: @michaelalbertmdWebsite: MichaelAlbertMD.com#GLP1 #Medicare #MedicareCoverage #ObesityMedicine #WeightLoss #HealthyAging #Zepbound #Wegovy________________________________________________________________________Join this channel to get access to perks: / @theplussidez______________________________________________________________________#Mounjaro #MounjaroJourney #Ozempic #Semaglutide #tirzepatide #GLP1 #Obesity #zepbound #wegovy #ObesityCare #PatientAdvocate #GLP1Community #RealGLP1StoriesSend us Fan Mail!Use Honest Care to Appeal GLP-1 Denials. Go to HonestCare.com/Kim Honest Care can Appeal GLP-1 Denials. Go to FindHonestCare.com/Kim Support the showKim Carlos, Executive Producer TikTokInstagram Kat Carter, Producer TikTokInstagram
Why did the Norwegian World Cup team bring their own food to America? Why do the Japanese celebrate victories with organized celebrations and New Yorkers burn buses?*The is the FREE archive, which includes advertisements. If you want an ad-free experience, subscribe below.
Millions of Medicare beneficiaries are about to gain access to GLP-1 weight loss medications for as little as $50 per month through the new Medicare Bridge Program, launching July 1. In this episode of On The Pen, Dave Knapp sits down with obesity medicine expert Angela Fitch to break down exactly who qualifies, how to apply, which medications are covered, and what this historic expansion of obesity treatment access means for patients across America.We discuss:✅ Medicare Bridge Program eligibility requirements✅ Zepbound, Wegovy, Foundayo (orforglipron), and GLP-1 coverage updates✅ BMI and comorbidity qualifications✅ Prediabetes, sleep apnea, cardiovascular disease, and obesity treatment access✅ How Medicare patients can obtain GLP-1 medications✅ Why obesity is finally being treated as a chronic disease✅ The future of obesity medicine and Medicare coverage✅ Concerns about access to care vs access to medication✅ Muscle loss, nutrition, strength training, and healthy weight loss✅ The Treat and Reduce Obesity Act (TROA)This may be one of the most important developments in obesity treatment history, potentially opening the door for millions of Americans living with obesity, prediabetes, cardiovascular disease, and other weight-related conditions to receive evidence-based care.
Gluttony, stress, exhaustion, and unhealthy habits are often treated as merely physical problems. In this episode, Costi Hinn explains why these issues have spiritual implications and how believers can pursue a healthier, more faithful life.
I am delighted to have Dr. Ken Berry returning to the podcast for his fourth appearance today. He is a physician, bestselling author, and passionate advocate for health, known for his no-nonsense approach to wellness. Dr. Berry has practiced at the Berry Clinic since 2003 and is an active community member. He has a YouTube channel with more than 2 million subscribers- one of my favorite go-to resources for patients. In our discussion today, we explore a recent Time news article and the growing concerns around the declining trustworthiness of media sources. We dive into the limitations of observational research, the problem with celebrity endorsements of ultra-processed foods, rising obesity rates in children and teens, and whether genetic factors are actually behind obesity, as highlighted recently in a 60 Minutes segment. We also discuss the impact of sugar, grains, and seed oils, as well as the significance of visceral fat. You will not want to miss this invaluable discussion with Dr. Ken Berry. IN THIS EPISODE YOU WILL LEARN: Dr. Berry breaks down some deeper issues surrounding the recent Time article, where a lone registered dietitian claimed that ultra-processed foods are acceptable. How media sources are losing their credibility The vital part social media plays in changing the narrative and holding media sources accountable Why consumers must stay informed and be proactive in their health choices The health implications of eating ultra-processed foods Dr. Berry shares his concerns about the American Academy of Pediatrics recommending drugs like Ozempic for children. The benefits of eating whole foods Dr. Berry shares his three rules for a healthy diet. Why we need to avoid sugar and seed oils How following a low-carb diet can help reduce visceral fat. Dr. Berry introduces the American Diabetes Society and explains its mission. Bio: Dr. Ken D. Berry, MD, is a licensed family physician, best-selling author, and leading advocate for the Proper Human Diet (PHD). With over two decades of clinical experience, Dr. Berry specializes in helping patients improve their health through low-carbohydrate, nutrient-dense eating. His best-selling book, "Lies My Doctor Told Me: Medical Myths That Can Harm Your Health," and his popular YouTube channel, which has over 3 million subscribers, provide accessible, evidence-based guidance on nutrition and wellness. Dr. Berry's mission is to empower individuals to reclaim their health by debunking common medical myths and promoting sustainable dietary and lifestyle changes. He is also a member of the Diet Doctor low-carb expert panel and an active participant in the keto and low-carb communities. Dr. Berry lives with his wife Neisha and their children on a farm in Holladay, Tennessee. Connect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia's website. Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow. Purchase Cynthia's book, The Menopause Gut. Cynthia's Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Connect with Dr. Ken Berry On his website YouTube Dr. Berry's Books The American Diabetes Society
A patient asked me this recently: "Dr. Shelley, I've heard that GLP-1 medications can cause muscle loss. Does that mean they can hurt my bones too?" It's an excellent question—and one we don't talk about nearly enough. In this episode, I'm walking you through what the research actually shows about GLP-1 medications and bone health, why weight loss itself poses a different risk to your skeleton, and the five non-negotiable steps you need to take to protect your bones while losing weight. This is the bone health conversation you need to hear before—or while—taking a GLP-1. Episode Highlights: What GLP-1 medications are and how they work in your body Does GLP-1 directly damage bones? What the research says The real issue: weight loss and how it affects bone health How your bones stay strong and why muscle matters Muscle loss during weight loss on GLP-1s (body composition breakdown) Who's at higher risk for weak bones and should be monitoring Eat enough protein: how much you actually need Strength training and resistance exercises for bone protection Getting enough calcium and vitamin D The DEXA bone density scan and when you should ask for one Connect with Dr. Alicia Shelly: Website | drshellymd.com Facebook | www.facebook.com/drshellymd Instagram | @drshellymd Linked In | www.linkedin.com/in/drshellymd Twitter | @drshellymd About Dr. Alicia Shelly Dr. Alicia Shelly was raised in Atlanta, GA. She received her Doctorate of Medicine from Case Western Reserve University School of Medicine in Cleveland, OH. Dr. Shelly has been practicing Primary Care and Obesity medicine since 2014. In 2017, she became a Diplomat of the American Board of Obesity Medicine. She is the lead physician at the Wellstar Medical Center Douglasville. She started a weekly podcast & Youtube channel entitled Back on Track: Achieving Healthy Weight loss, where she discusses how to get on track and stay on track with your weight loss journey. She has spoken for numerous local and national organizations, including the Obesity Medicine Association, and the Georgia Chapter of the American Society of Metabolic and Bariatric Surgeons. She has been featured on CNN, Fox 5 News, Bruce St. James Radio show, Upscale magazine, and Shape.com. She was named an honoree of the 2021 Atlanta Business Chronicle's 40 under 40 award. She also is a collaborating author for the, "Made for More: Physician Entrepreneurs who Live Life and Practice Medicine on their own terms''. Resources: FREE! Discover the 5 Reasons Your Weight-Loss Journey Has Gotten Derailed (And How To Get Back On Track!)
Professor Donal O'Shea, specialist in obesity, responds to the National Centre for Pharmacoeconomics comments that Mounjaro could be deemed cost effective.
Hour 2 of the Monday 6-22-26 Bob Rose Show, on the first positive obesity news in 50 years. Is it MAHA, or ‘the shot.' RFK Jr. touted the overall health benefits, national security implications for overweight youth, nutritional deficiencies, sugar, and fad diets. Plus, all the morning's biggest news stories
Jordan Sather and Nate Prince are back in a pre-recorded episode packed with substance. Nearly two thirds of American men are overweight or obese, but for the first time in 50 years obesity rates have ticked down. Is it MAHA, peptides, or just economic stress cutting back the Cheez-It budget? RFK sends a formal letter demanding answers from a medical journal that quietly removed a study linking vaccines to SIDS, and Big Pharma's media allies are furious that someone had the audacity to ask why. Ron Johnson and Rand Paul keep pressing on COVID shot injuries while legacy media stays conspicuously silent. Nineteen medical schools just signed a nutrition education pledge requiring 40 hours of training as a graduation standard. The US lost 140,000 farms and 20 million acres between 2017 and 2022, and Jordan has thoughts about developers, HOA lawns, and the slow death of the American farmer. And finally, a new full body imaging machine using ultrasonic waves scans you head to toe in 60 seconds with no radiation. Imagine a $30 full body scan. Jordan is already imagining it.
Nature staff discuss preliminary data on the effects of GLP-1 drugs on male fertility plus a two-year trial of a brain-computer interface.00:18 Brain-computer interface makes a life-changing impactNature: At-home brain implant gives man with motor neuron disease his daily life back05:39 The possible benefits of obesity drugs on testosteroneNature: The latest benefit of obesity drugs: boosting testosterone and sperm qualitySubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday. Hosted on Acast. See acast.com/privacy for more information.
Nutrition Nugget! Bite-sized bonus episodes offer tips, tricks and approachable science. This week, Jenn is talking about meals on repeat and whether eating the same foods over and over aids in weight loss. A new study claims that less variety in your diet is associated with better results, but is that the full picture? Jenn dives into the research, the numbers, and what they really mean, while questioning whether a 12-week study tells the whole story. Does sticking to the same meals set you up for long-term success, or could it backfire down the road? Tune in to hear Jenn break it all down and find out what she really thinks. Like what you're hearing? Be sure to check out the full-length episodes of new releases every Wednesday. Have an idea for a nutrition nugget? Submit it here: https://asaladwithasideoffries.com/index.php/contact/RESOURCES:Become a Happy Healthy Hub MemberJenn's Free Menu PlanA Salad With a Side of FriesA Salad With A Side Of Fries MerchA Salad With a Side of Fries InstagramKEYWORDS: Jenn Trepeck, Nutrition Nugget, Salad With A Side Of Fries, Health Tips, Wellness Tips, Meals on Repeat, Weight Loss Research, Weight Loss Tips, Weight Loss, Meal Planning, Dietary Repetition, Caloric Stability, Calorie Tracking, Behavioral Weight Loss, MyFitnessPal, Food Logs, Weight Loss Program, Health Psychology, BMI, Overweight, Obesity, Meal Prep, Healthy Eating, Nutrition Tips, Wellness Coach, Diet Routine, Food Variety, Repetitive Meals, Self Control, Weekend Eating Habits, Weekday Eating Habits, Correlation Vs Causation, Diet Studies, Sustainable Weight Loss, Yo Yo Dieting, Healthy Habits, Food Tracking, Calorie Deviation, Diet Boredom, Real Food Coaching, Weight Loss Strategies, Nutrition Myths, Diet Research, Eating Patterns, Salad With A Side Of Fries, Jenn Trepeck, Health Coaching, Body Weight Management, Does Eating The Same Meals Help You Lose Weight, Benefits Of Meal Repetition For Weight Loss
Coca-Cola spent $118 million to shape nutrition science, emphasizing energy balance over sugar and exercise. The Global Energy Balance Network was exposed as a front for industry influence, leading to the disbandment of the network and the departure of a top Coca-Cola science executive. This highlights the distortion of obesity science by corporate money and the need for critical evaluation of nutrition headlines.TakeawaysCorporate funding can distort nutrition scienceCritical evaluation of nutrition headlines is essentialChapters00:00 The Influence of Corporate Funding on Nutrition Science06:05 Distortion of Obesity Science by Corporate Money
Send us Fan MailGLP-1 drugs have produced some of the most consistent weight loss results medicine has ever seen. The business of actually getting them to patients is a different story entirely.David E. Williams, President of Health Business Group, and John Driscoll, Chairman of UConn Health, break down the CVS Caremark formulary reversal on CareTalk, examining what it reveals about the economics of GLP-1 coverage, and why emerging clinical research on cancer, long COVID, and addiction may push these drugs far beyond their original indication.
The World Cup is here, and while we watch some of the world's greatest athletes competing on a global stage, it's fascinating to consider what effect this intense activity may have on the human body. With that in mind, we're re-releasing our conversation with Stanford biochemist Jonathan Long on the future of exercise. Jonathan studies the chemistry of what happens inside your body when you move, and his findings are pointing toward some genuinely surprising possibilities — including treatments for obesity, diabetes, and even, someday, an exercise pill. If the athleticism on the pitch has you feeling inspired, this one is well worth another listen. Have a question for Russ? Send it our way in writing or via voice memo, and it might be featured on an upcoming episode. Please introduce yourself, let us know where you're listening from, and share your question. You can send questions to thefutureofeverything@stanford.edu. Episode Reference Links: Stanford Profile: Jonathan Long Connect With Us: Episode Transcripts >>> The Future of Everything Website Connect with Russ >>> Threads / Bluesky / Mastodon Connect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / Facebook Chapters: (00:00:00) Introduction Russ Altman introduces guest Jonathan Long, a professor of pathology from Stanford University. (00:02:02) Effective Weight Loss Drugs The history and development of GLP-1 receptor agonists. (00:04:04) Understanding Metabolism and Exercise Why Long's lab starts with molecules to understand metabolism and physical activity. (00:05:10) Animal Models in Exercise Studies The use of animal models in exercise studies and the discovery of Lac-Phe. (00:06:47) Psychological Preparation for Exercise The psychological aspects of exercise and the involvement of endocannabinoids in exercise motivation. (00:09:00) Lac-Phe's Role and Mechanism The role of Lac-Phe and its production in the gut. (00:12:08) Differences in Exercise Response Differences in exercise response between trained athletes and untrained individuals. (00:12:57) Diabetes and Metabolic Diseases The relationship between diabetes, exercise, and metabolic diseases. (00:15:01) Lac-Phe as a Potential Therapeutic The potential of Lac-Phe as a weight loss drug, and parallels to GLP-1 drug development. (00:16:21) Importance of How Weight is Lost Whether the method of weight loss matters, and the importance of preserving lean muscle mass. (00:18:37) Exercise as Medicine The concept of exercise as medicine, and defining physical activity at the same resolution as modern medicines. (00:22:11) Metformin and Exercise Pathways The unexpected connection between metformin and the Lac-Phe pathway. (00:24:01) Prospects of an Exercise Pill The future of an exercise pill, and the challenges associated with its development. (00:27:05) Conclusion Final thoughts on the future of exercise. Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>>Twitter/X / Instagram / LinkedIn / Facebook Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Doctor Mau Informa ®️ #drmauinforma Durante medio siglo, la endocrinología consideró al glucagón como el "villano" del metabolismo: la hormona responsable de subir el azúcar en la sangre. Sin embargo, ¿qué pasaría si pudiéramos domesticar a este villano para activar la quema extrema de grasa de forma segura. En este episodio de Doctor Mau Informa, analizamos la fascinante evolución científica que nos llevó desde tumores pancreáticos hasta el desarrollo del Retatrutide, un revolucionario fármaco "triple agonista". Descubre cómo la ciencia logró combinar tres señales hormonales (Glucagón, GLP-1 y GIP) en una sola inyección semanal para alcanzar resultados de pérdida de peso metabólica que antes solo le pertenecían al bisturí de la cirugía bariátrica. En este episodio aprenderás: → La balanza de la pérdida de peso: Por qué los medicamentos anteriores solo te quitaban el hambre, y cómo la nueva generación también acelera tu gasto energético. → El secreto del Glucagón: Cómo esta hormona del ayuno saca la grasa del hígado y eleva el metabolismo. → La evolución del GLP-1: El papel protector de la insulina natural para contrarrestar el azúcar y permitir una pérdida de peso segura. → Cirugía vs. Fármacos: Por qué los resultados de los nuevos tratamientos crónicos están cambiando el paradigma médico para siempre. → La realidad clínica: Efectos secundarios, la importancia de la titulación médica y por qué esto no es una "dieta milagro".
#thismorning | #Phantom #Obesity: The Dark Side of #WeightLoss | Thomas Rutledge, PhD., UC San Diego | #Tunein: broadcastretirementnetwork.com #Aging, #Finance, #Lifestyle, #Privacy, #Retirement, #wellness
In this episode of The Pet Food Science Podcast Show – Equine, Dr. Kris Hiney from Oklahoma State University discusses practical strategies for managing overweight horses. She explains the health consequences of obesity, challenges with pasture access and boarding facilities, forage management, grazing muzzles, slow feeders, nutrient balance, and owner compliance. Dr. Hiney also shares realistic approaches that support both horse welfare and long-term weight management. Listen now on all major platforms!"Successful weight management programs depend on realistic recommendations that fit facility resources, management practices, and the horse's social environment."Meet the guest: Dr. Kris Hiney is an Associate Professor and Equine Extension Specialist at Oklahoma State University. She earned her Ph.D. in Animal Sciences from Michigan State University and has developed educational programs focused on equine nutrition, health, management, behavior, and welfare. Her work helps horse owners apply science-based practices to improve horse well-being and performance. Listen to Dr. Kris Hiney on The Pet Food Science Podcast Show – Equine, available on all major platforms.Liked this one? Don't stop now — Here's what we think you'll love!Don't miss the chance to be part of the Pet Food Inner Circle!Join now and connect with leading experts in pet nutrition: https://petfoodinnercircle.com/What will you learn:(00:00) Highlight(01:10) Introduction(03:13) Obesity health impacts(06:37) Practical feeding strategies(10:33) Boarding barn challenges(13:15) Horse welfare management(23:56) Weight loss compliance(28:26) Final QuestionsThe Pet Food Science Podcast Show is trusted and supported by innovative companies like:* Trouw Nutrition* Kemin- Rangen Group- Biorigin- DietForge
Exam Room Nutrition: Nutrition Education for Health Professionals
What Really Happens Inside an Obesity Clinic GLP-1 medications are everywhere right now. Patients are asking about Ozempic, Wegovy, Zepbound, compounded medications, muscle loss, “Ozempic face,” insurance denials, and what happens when the weight loss slows down.But what does obesity medicine actually look like inside the clinic? In this episode, I'm joined by Joseph Zucchi, PA-C, clinical supervisor and physician associate at Transition Medical Weight Loss in Salem, New Hampshire. This is not your typical GLP-1 conversation. We're going beyond protein goals, nausea tips, and constipation management to talk about what clinicians are really facing in practice: how to dose these medications, when to switch, and how to support patients when insurance coverage disappears.In this episode, you'll learn:What to assess when a patient hits a weight loss plateau beyond simply increasing the dose How to talk with patients about GLP-1 concerns like muscle loss, thyroid cancer warnings, GI side effects, and “Ozempic face” Why obesity medications are tools, not “cheating,” and how to address weight stigma in the exam room What clinicians should know about compounded GLP-1 medications and why FDA-approval matters How to document for prior authorizations and what insurance companies are often looking for What happens when patients lose GLP-1 coverage and how to discuss alternative medication options What Joe is most excited about in the future of obesity medicine, including new medications and expanding coverage If you prescribe GLP-1 medications, counsel patients on weight management, or feel overwhelmed by the insurance and documentation side of obesity medicine, this episode will give you a practical, behind-the-scenes look at what comprehensive obesity care can look like.Connect with JoeResources mentioned:Obesity Medicine Nutrition Course (with a 2026 medication update) Use code POD15 for 15% off!155 | Unstuck: Strategies for Sustainable Weight Loss151 | Are GLP-1s Masking Undiagnosed Eating Disorders?Obesity Medication InfographicAny Questions? Send Me a MessageSupport the showConnect with Colleen:InstagramLinkedInSign up for my FREE Newsletter - Nutrition hot-topics delivered to your inbox each week.Disclaimer: This podcast is a collection of ideas, strategies, and opinions of the author(s). Its goal is to provide useful information on each of the topics shared within. It is not intended to provide medical, health, or professional consultation or to diagnosis-specific weight or feeding challenges. The author(s) advises the reader to always consult with appropriate health, medical, and professional consultants for support for individual children and family situations. The author(s) do not take responsibility for the personal or other risks, loss, or liability incurred as a direct or indirect consequence of the application or use of information provided. All opinions stated in this podcast are my own and do not reflect the opinions of my employer.
While we won't trot out the tired adage detailing how women are from Venus…
ADA 2026 delivered a massive wave of obesity and diabetes data, and in this episode of On The Pen, Dave Knapp (@manonthemounjaro) sits down witH to break down the molecules, clinical trials, weight loss results, and safety signals that could define the next generation of obesity and diabetes medicine.We dive deep into Survodutide, Mazdutide, UBT251, Berobenatide (MET-097), CagriSema, Zenagamtide (formerly Amycretin), Petrelintide, and so much more!From GLP-1/glucagon dual agonists to triple agonists targeting GLP-1, GIP, and glucagon, the obesity treatment landscape is becoming more competitive than ever. Which therapies showed the strongest weight loss? Which struggled with tolerability? And what do these results mean for patients living with obesity, type 2 diabetes, MASLD, sleep apnea, and other metabolic diseases?In this episode:✅ Survodutide obesity and liver fat reduction data✅ Mazdutide Phase 3 obesity and diabetes results✅ UBT251 triple agonist weight loss data✅ Berobenatide (MET-097) long-acting GLP-1 updates✅ CagriSema diabetes and obesity trial results✅ Zenagamtide (Amycretin) injectable and oral development✅ Petrelintide amylin agonist info✅ Future GLP-1, GIP, glucagon, and amylin therapiesThe future of obesity medicine is no longer just about who produces the most weight loss. It's about matching the right therapy to the right patient, improving tolerability, and addressing metabolic disease beyond the number on the scale.Read more obesity medicine news at obesity.news
In this episode of the Heart podcast, Digital Media Editor, Professor James Rudd, is joined by Professor Carel le Roux from University College, Dublin and Ulster University. They discuss the trial evidence that has emerged over the last 20 years for both bariatric surgery and the newer GLP-1 medications, focusing particularly on reductions in cardiovascular outcomes. They also discuss where the field of obesity intervention might head over the next five years and how metabolic surgery will continue to have an important role. If you enjoy the show, please leave us a positive review wherever you get your podcasts. It helps us to reach more people - thanks! Link to published paper: https://heart.bmj.com/content/early/2026/02/23/heartjnl-2025-326812
Prostate cancer is the most commonly diagnosed cancer among men and remains a leading cause of cancer-related death worldwide. While age, family history, and genetics are well-established risk factors, researchers have increasingly focused on the role of metabolic health in prostate cancer progression. Obesity, insulin resistance, type 2 diabetes, and chronic inflammation have all been associated with more aggressive disease, but the molecular mechanisms connecting these conditions to prostate cancer remain incompletely understood. A research paper titled “Epigenetic dysregulation and biological function of PDX1 in prostate cancer” was published in Volume 17 of Oncotarget. In this study, the researchers investigated whether a gene best known for regulating pancreatic function may also play an important role in prostate tumor biology. The study was led by first author Tayo A. Adeyika and corresponding author Bernard Kwabi-Addo from Howard University, Washington, DC. Full blog - https://www.oncotarget.org/2026/06/16/pdx1-may-link-metabolic-dysfunction-to-prostate-cancer-progression/ DOI - https://doi.org/10.18632/oncotarget.28854 Correspondence to - Bernard Kwabi-Addo - bkwabi-addo@howard.edu Abstract video - https://www.youtube.com/watch?v=itYVsyXJJoE Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28854 Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ Keywords - cancer, PDX1, DNA methylation prostate cancer, shRNA knockdown, over-expression, glucose To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM
Could you have metabolic dysfunction even at a normal weight?This episode challenges everything we've been taught about weight and health. Dr. Cooper reveals that up to 25% of normal-weight people have metabolic syndrome, yet they're rarely screened because doctors assume they're healthy based on appearance alone.KEY TAKEAWAYSWeight and metabolic health are not the same thing - you can be metabolically unhealthy at any sizeNormal weight people with metabolic dysfunction are often overlooked and undertreated by healthcare providersKey screening tests include fasting glucose, insulin, HbA1c, triglycerides, HDL cholesterol, blood pressure, and inflammatory markers like HSCRPMetabolic dysfunction can start in your 20s and take decades to develop into serious diseaseBoth normal weight and higher weight patients face bias - normal weight people aren't screened enough, while higher weight people have everything blamed on their weightEarly screening and treatment can prevent catastrophic health outcomes later in lifeThe liver plays a crucial role in metabolism and can become insulin resistant regardless of body weightNOTABLE QUOTE"You cannot tell anything about someone's health from their outside, what they look like or what, even what they're doing necessarily, but definitely not their body size. So you can be healthy or unhealthy at any size body, and I think that's what's overlooked quite a bit." — Dr. Emily CooperLinks & ResourcesPodcast Home: fatsciencepodcast.comCooper Center for Metabolism: coopermetabolic.comResources from Dr. Cooper: coopermetabolic.com/resourcesJoin Our Community: patreon.com/cw/FatSciencePodcastSubmit Your Question: questions@fatsciencepodcast.com or dr.c@fatsciencepodcast.comAppendix: Key ReferencesPrimary literature supporting this episode• Wang et al. Prevalence of Metabolically Unhealthy Normal Weight and Its Influence on the Risk of Diabetes. Journal of Clinical Endocrinology & Metabolism, 2023.• Review: Beyond BMI — Rethinking Obesity Metrics and Cardiovascular Risk in the Era of Precision Medicine. Journal of Clinical Medicine, December 2025.• Korean meta-analyses on metabolic dysfunction phenotypes and cardiometabolic risk, Cardiovascular and Metabolic Sciences Journal review, 2024.• Frontiers in Nutrition, January 2026. Associations of metabolic heterogeneity with the progression of cardiometabolic multimorbidity.• International Journal of Obesity, September 2025. Cardiovascular risk factors associated with metabolic health phenotypes.Mechanism references• MASLD — metabolic dysfunction-associated steatotic liver disease — nomenclature and clinical framework. AASLD/EASL consensus, 2023.• Insulin signaling, adipose tissue dysfunction, and ectopic fat deposition — reviews on the upstream-downstream relationship.• Epicardial adipose tissue and cardiovascular dysfunction — Frontiers in Cardiovascular Medicine, January 2026.Fat Science is supported by the Diabesity Institute, a nonprofit dedicated to increasing access to effective, science-based metabolic care.This podcast is for informational purposes only and is not intended as medical advice. Please consult with a qualified healthcare provider for personalized recommendations.
Can retatrutide finally be the breakthrough obesity treatment we've been waiting for? The answer is yes—and the data is stunning. In this episode I'm walking you through the biggest obesity medicine discovery from the ADA's 86th Scientific Session: retatrutide, a triple hormone receptor agonist showing weight loss results that rival bariatric surgery. You'll learn what makes retatrutide different from Wegovy and Zepbound, the stunning results from the Triumph 1 trial, what the side effects actually look like, and when this medication will finally be available. Weight loss medications are evolving faster than ever. But what you really need to know is what these results mean for your health. Listen now! Episode Highlights: Retatrutide is a triple hormone agonist that targets GLP-1, GIP, and glucagon receptors Participants lost an average of 28.3% of their body weight in 80 weeks Two-thirds of participants achieved a normal BMI—moved from obese to healthy weight Nearly everyone with prediabetes reversed it and returned to normal blood sugar Over 70% reduction in knee osteoarthritis pain and 60% reduction in sleep apnea severity The highest discontinuation rate due to side effects was only 11%—mainly GI issues Retatrutide is not yet FDA approved but anticipated to launch early 2027 Connect with Dr. Alicia Shelly: Website | drshellymd.com Facebook | www.facebook.com/drshellymd Instagram | @drshellymd Linked In | www.linkedin.com/in/drshellymd Twitter | @drshellymd About Dr. Alicia Shelly Dr. Alicia Shelly was raised in Atlanta, GA. She received her Doctorate of Medicine from Case Western Reserve University School of Medicine in Cleveland, OH. Dr. Shelly has been practicing Primary Care and Obesity medicine since 2014. In 2017, she became a Diplomat of the American Board of Obesity Medicine. She is the lead physician at the Wellstar Medical Center Douglasville. She started a weekly podcast & Youtube channel entitled Back on Track: Achieving Healthy Weight loss, where she discusses how to get on track and stay on track with your weight loss journey. She has spoken for numerous local and national organizations, including the Obesity Medicine Association, and the Georgia Chapter of the American Society of Metabolic and Bariatric Surgeons. She has been featured on CNN, Fox 5 News, Bruce St. James Radio show, Upscale magazine, and Shape.com. She was named an honoree of the 2021 Atlanta Business Chronicle's 40 under 40 award. She also is a collaborating author for the, "Made for More: Physician Entrepreneurs who Live Life and Practice Medicine on their own terms''. Resources: FREE! Discover the 5 Reasons Your Weight-Loss Journey Has Gotten Derailed (And How To Get Back On Track!)
Donal O'Shea, endocrinologist and HSE Clinical Lead on Obesity
Dr. Galati plays an extended interview he had with Bariatric Surgeon Dr. Garth Davis earlier this week. They talk about obesity, the new GLP-1 agents, his thoughts on diet/exercise, and bariatric surgery.
In the United States, the percentage of obese adults is about ten times what it is in Japan, even though fast food, junk food, pizza and donuts are popular. Correspondent Adam Yamaguchi looks at what differentiates the Japanese diet. Actor Bill Mumy first became known for his childhood appearances on classic series such as "The Twilight Zone", and later as Will Robinson on "Lost in Space". Correspondent Jim Axelrod discovers how Mumy, now 72, avoided the dangers that other child actors faced while pursuing a Hollywood career.Vice President JD Vance and his wife, Usha, are expecting their fourth child. They talked with "Sunday Morning" national correspondent Robert Costa about family, his conversion to Catholicism, and his book, "Communion: Finding My Way Back to Faith".
GLP-1 drugs were first approved to treat diabetes and then caused a frenzy when it was discovered they were great for weight loss. But now scientists are discovering the drugs that have brand names including Ozempic and Mounjaro might offer so much more, from reducing the risk of heart attack to treating kidney disease. Today, Doctor Paul Joyce, a pharmaceutical scientist at Adelaide University on how Ozempic is shaking things up, again. Featured: Doctor Paul Joyce, a pharmaceutical scientist at Adelaide University
Welcome back to this week's episode. I'm thrilled to have a truly exceptional guest joining me in the studio today—Dr. Garth Davis, a highly respected bariatric surgeon based in Houston, Texas, who brings decades of experience to the frontlines of obesity medicine.Dr. Davis has dedicated his career not only to performing life-changing surgeries but to fundamentally rethinking how we approach weight management and metabolic health. He's the author of "Proteinaholic," a thought-provoking book that challenges conventional wisdom about dietary protein, and he's become a passionate advocate for plant-based nutrition and increasing food literacy across all age groups.In our wide-ranging conversation today, we dive deep into the current obesity epidemic, exploring Dr. Davis's comprehensive management philosophy for patients dealing with obesity and metabolic syndrome. We discuss the evolving toolkit available to clinicians—from dietary interventions and the revolutionary GLP-1 agonists that are transforming the field, to the role of bariatric surgery and when it becomes the right choice.Dr. Davis doesn't hold back in sharing his personal journey toward veganism and how it's shaped his medical practice. Whether you're a healthcare professional, someone on your own health journey, or simply curious about the science behind weight management, this episode offers invaluable insights you won't want to miss.How To Reach Dr. Joe Galati and his Team:For an on-line consultation or press inquiries, contact Teresa Reyes at 713-794-0700Dr. Galati's Newsletter Sign-UpLiver Specialists of TexasGet a Copy of Dr. Galati's BookDr. Galati on FacebookMessage Dr. Galati and his team Hosted on Acast. See acast.com/privacy for more information.
You're not over-fat. You're under-muscled. That single reframe changes how you think about your weight, your energy, and how well you'll age. Dr. Gabrielle Lyon, a fellowship-trained geriatrician and the founder of muscle-centric medicine, has spent her career arguing that we've fixated on the wrong organ. Obesity, insulin resistance, even cognitive decline don't start where you think. They start in your muscle. She breaks down why muscle is your metabolic currency, your body armor, and the closest thing we have to a longevity drug. And why the protein advice most people follow was set during wartime rationing, not built for the life you're trying to live. The hard part isn't the science. It's that the changes stay subtle until one day they're not. This conversation will make you rethink every plate of food and every workout you skip. Forever Strong: A New, Science-Based Strategy for Aging Well Amazon Ebook Audiobook Dr. Lyon on Instagram Dr. Lyon on YouTube DrGabrielleLyon.com In this episode you will: Discover why your muscle, not your body fat, is the real driver of metabolic health and survival Learn the leucine meal threshold and the protein number to hit at your first meal Understand anabolic resistance and why you need more protein, not less, as you age Uncover where the 0.8g/kg protein guideline actually came from and why it falls short Rethink cardio versus resistance training and build a plan that protects muscle for life For more information go to https://lewishowes.com/1940 For more Greatness text PODCAST to +1 (614) 350-3960 Follow The Daily Motivation for essential highlights from The School of Greatness More SOG episodes we think you'll love: Dr. Mark Hyman Dr. William Li Glucose Goddess TOPICS muscle-centric medicine, skeletal muscle, protein and longevity, leucine threshold, anabolic resistance, sarcopenia, insulin resistance, healthy aging, Dr. Gabrielle Lyon Get More From Lewis! Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
The optimal intake of dietary cholesterol may be zero.
Editor's Summary by Kirsten Bibbins-Domingo, PhD, MD, MAS, Editor in Chief, Linda Brubaker, MD, Deputy Editor, and Christopher W. Seymour, MD, MSc, Associate Editor of JAMA, the Journal of the American Medical Association, for articles published from June 6-12, 2026. Related Content: Audio Highlights
Καλεσμένος ο Δρ. Αριστομένης Τουρβάς, Παθολόγος–Εντατικολόγος, με πιστοποίηση SCOPE και εξειδίκευση στην παχυσαρκία. Μια νέα εποχή φαίνεται να ξεκινά στην αντιμετώπιση της παχυσαρκίας. Σε κλινικές μελέτες ενός νέου φαρμάκου, ασθενείς έχασαν πάνω από το 25% του βάρους τους. Μέσα σε λίγα χρόνια, φάρμακα όπως το Ozempic, το Wegovy και το Mounjaro πέρασαν από τα ιατρεία και τα επιστημονικά συνέδρια, στα πρωτοσέλιδα, στα social media και στις καθημερινές συζητήσεις. Για κάποιους αποτελούν μια επανάσταση στην ιατρική. Για άλλους, μια εξέλιξη που συνοδεύεται από μεγάλες προσδοκίες αλλά και σημαντικά ερωτήματα για την ασφάλεια, τη χρήση και το μέλλον τους. Μπορούν πραγματικά αυτά τα φάρμακα να αλλάξουν τον τρόπο με τον οποίο αντιμετωπίζουμε την παχυσαρκία; Πόσο αποτελεσματικά και πόσο ασφαλή είναι; Σε ποιους απευθύνονται; Και βρισκόμαστε πράγματι μπροστά σε μια νέα εποχή στην ιατρική; Ίσως στη σημαντικότερη εξέλιξη στην αντιμετώπιση της παχυσαρκίας από τότε που η ιατρική άρχισε να τη θεωρεί νόσο;
A new, comprehensive study takes a look at lifestyle factors and colorectal cancer in younger people and fails to find a relationship. Kimmel Cancer Center director William Nelson at Johns Hopkins says he thinks it may be more subtle and … Is there a relationship between diet, obesity and colorectal cancer? Elizabeth Tracey reports Read More »
Dr Jason Fung discusses the complex causes of obesity and hunger, emphasising hormonal influences over simplistic calorie models. He explores the history of dietary guidelines, the role of insulin, and the social and emotional factors affecting eating behaviours.
In Part 2, Naveed Sattar discusses obesity, ectopic fat, and cardiovascular risk. Learn how imaging and biomarkers are improving risk identification, why metabolic dysfunction matters beyond BMI, and how GLP-1 therapies are reshaping obesity and cardiovascular care. Timestamps: 0:56 – Ectopic fat 11:44 – Metabolic dysfunction 13:42 – GLP-1 receptor agonists 19:05 – Mechanistic insights 21:31 – Societal issues
With the launch of a new journal, the American Diabetes Association (ADA) is also launching a brand new podcast: The Points of CARE, the official podcast of Diabetes, Obesity, and CardioMetabolic CARE. Join hosts Richard Beaser, MD and Jane Reusch, MD, as they highlight key research findings, clinical implications, and emerging themes across diabetes, obesity, and cardiometabolic health through interviews with journal authors and subject-matter experts. 4:05 Our hosts speak with Anna Kahkoska, MD, PhD, Joan Heckler Gillings Assistant Professor in the Department of Nutrition and adjunct assistant professor of medicine in the Division of Endocrinology and Metabolism at the University of North Carolina at Chapel Hill, as well as Joshua Niznik, PharmD, PhD, assistant professor in the Division of Geriatric Medicine within the UNC School of Medicine. Their article, "Qualitative Analysis of Patient Portal Messages From Older Adults With Type 2 Diabetes," is available at doi.org/10.2337/doc25-0079. 14:10 Our hosts introduce Esben Thyssen Vestergaard, PhD, clinical associate professor in the Department of Clinical Medicine and Department of Pediatrics Aarhus University in Aarhus, Denmark. His article, "Clinic for Athletes With Type 1 Diabetes: Evaluation of a Structured Clinical Care Model for Physically Active Individuals," is available for free at doi.org/10.2337/doc25-0064. 21:40 Finally, Richard and Jane highlight some of their favorite articles from the May-June issue. Rezaeiahari, et al. Rural–Urban Differences in Use of Diabetes Self-Management Education and Support in Arkansas, 2015–2019 doi.org/10.2337/doc25-0065 Liu, et al. Trends in Nutrient Intake Among U.S. Adults by Diabetes Status: National Health and Nutrition Examination Survey 2011–2020 doi.org/10.2337/doc25-0076 Yanez Bello, et al. Barriers to the Adoption of Diabetes Technologies and the Implementation of Connected Insulin Pens in a Largely Minority Population With Type 1 Diabetes doi.org/10.2337/doc25-0072 Shehab, et al. Barriers to Effective Type 2 Diabetes Care in a Conflict-Affected Region of Syria: A Qualitative Study of Health Care Provider Perspectives doi.org/10.2337/doc26-0021 ElSayed, et al. Enhancing Physician Clinical Competency: A Cluster Randomized Trial of a Multimodal Online Educational Program in a Multinational Diabetes Workforce doi.org/10.2337/doci25-0007 Olesen, et al. A Danish Nationwide Cohort of Foot Health in Individuals With Diabetes From the Danish Foot Status Database doi.org/10.2337/doc26-0002 To learn more about Diabetes, Obesity, and CardioMetabolic CARE please visit diabetesjournals.org/docm-care. Thank you for listening, and don't forget to subscribe.
Linktree for Community ResourcesNeed help appealing a GLP-1 Insurance Denial? FindHonestCare.com/KimRo - Telehealth for GLP1 Weight ManagementThe Absolute Lies You've Heard About GLP-1s (Ozempic Myths Debunked) [REPLAY]Are you being lied to about Ozempic, Mounjaro, and Wegovy? In this special replay episode, leading obesity medicine specialists break down the biggest GLP-1 myths taking over your feed. We are reposting this crucial conversation because it is more relevant than ever. With GLP-1 price changes and expanding access options through federal programs like the Medicare GLP-1 Bridge, understanding the real science behind these medications is essential for patient advocacy.We are sharing a few favorite replay episodes right now while Kim is away on bereavement leave following the loss of her sister. We want to deeply thank our subscribers for staying engaged and supporting the show during this time.In this episode of The Plus Sidez Podcast, Kat joins Kim to sit down with obesity medicine specialists Dr. Matea Rentea and Dr. Ali Novitzki to help listeners better understand their disease and feel empowered in their healthcare journey.The Myths We Debunk:The Muscle Loss Scare: The data behind weight loss and body composition, explaining why the medication itself is not destroying your lean mass.The Willpower Narrative: Why obesity is a genetic, chronic metabolic disease rooted in brain biology, not a failure of personal willpower.The Shot-Only Illusion: How the medication works alongside your body's natural satiety signals and gut receptors.Obesity Doctor Guidance Shared:Metabolic Protection: A practical discussion on utilizing a 10-minute fitness routine and a 100-gram protein framework to maintain lean mass and support insulin sensitivity.System Navigation: Insights on navigating insurance barriers, managing prior authorizations, and advocating for proper medical care.Mental Resilience: Tools to process unsolicited comments about your weight and protect your peace from societal judgment.Episode Topics:Why We Are Replaying This Episode: Prices, Access, and UpdatesThe Insurance Landscape: Understanding Prior AuthorizationsMeet the Obesity Medicine SpecialistsDeconstructing the GLP-1 Muscle Loss NarrativeStrategies for Protecting Your MetabolismWhat the Scales Do Not Show About Insulin ResistanceNatural Satiety Triggers and Gut ReceptorsRecognizing Obesity as a Biological Chronic DiseaseAddressing Weight Stigma and External CommentarySubscribe to The Plus Sidez Podcast for science-backed episodes breaking down metabolic health, body recomposition, and the truth about weight loss.Search TagsGLP1 lies debunked, Ozempic myths, Mounjaro weight loss journey, Wegovy truth, Zepbound body recomposition, insulin sensitivity hacks, natural GLP1 boosters, treating obesity metabolic disease, plus sidez podcast, dr matea rentea, dr ali novitzki_________________________________________________________________________Join this channel to get access to perks:https://www.youtube.com/channel/UC0HUIGKl3BN4Vg6LYI-dkOA/join_________________________________________________________________________#Mounjaro #MounjaroJourney #Ozempic #Semaglutide #tirzepatide #GLP1 #Obesity #zepbound #wegovySend us Fan Mail!Support the showKim Carlos, Executive Producer TikTokInstagram Kat Carter, Producer TikTokInstagram
Dr Deirdre Robertson, ESRI Associate Research Professor, explains research that shows differing opinions between the public and experts on the cause of the obesity epidemic.
Lindsey Bordone, MD, FAAD interviewed by Sabrina Shearer, MD, FAAD
A fitness creator posted about a woman's body, called it obesity, and the internet went into full meltdown — but was he wrong? We react to the viral post that racked up 1.5 million views, break down what "obese" actually means, and explain why BMI is an outdated tool that was never designed to measure your health. We also get into what actually matters — body fat percentage, where you carry your weight, and the waist-to-height ratio you should actually be paying attention to. Join this channel to get access to perks:https://www.youtube.com/channel/UC_8nonbBsA-mTli1KLlHlrA/joinWork with JeanineBook a free consult https://bit.ly/4dUHYZeMike's YouTube Channel: @escoelitemindsetMike's Instagram: https://www.instagram.com/@escoelitemindsetSupport our Sponsors1UP Nutrition Code: JEANINEhttps://1upnutrition.com/JEANINEHRT & Peptides (Tell them Jeanine Escobar when filling out ntake)https://www.vitabella.comMegaFit Meals - Code Jeanine10 https://megafitmeals.rfrl.co/p75q7Built Bar Code: MRSCEOJhttps://builtbar.com?baapp=MRSCEOJSupport us by following on Social MediaAmazon Storefront: https://www.amazon.com/shop/mrsceo_jLTK Fashion Links: https://www.shopLTK.com/explore/MrsCEO_JShopmy https://shopmy.us/shop/mrsceoj?Section_id=1519253&tab=collectionsInstagram: https://instagram.com/mrsceo_jInstagram: https://instagram.com/candidly_withcoffeeWeight Loss IG: https://instagram.com/@coach.jeanineescobarTikTok: https://www.tiktok.com/@mrsceo_j
Can I restart my GLP-1? The answer is yes — but it requires a strategic plan. In this episode I'm walking you through exactly what happens to your body when you restart a GLP-1, why the timing of your break matters more than you think, how to restart safely without landing yourself in misery, the biggest mistakes I see patients make, and how to get back on track without shame or guilt. Restarting doesn't have to mean starting completely over. But how you restart matters. Listen now! Episode Highlights: Why restarting at your previous dose will make you seriously sick What happens to your hunger, cravings, and fullness signals when you restart How long you've been off determines your restart dose The critical question that changes everything: weeks vs. months off Why weight regain after stopping is biology, not failure 3 practical strategies to minimize side effects and rebuild tolerance How to stay mentally on track without shame or comparison Connect with Dr. Alicia Shelly: Website | drshellymd.com Facebook | www.facebook.com/drshellymd Instagram | @drshellymd Linked In | www.linkedin.com/in/drshellymd Twitter | @drshellymd About Dr. Alicia Shelly Dr. Alicia Shelly was raised in Atlanta, GA. She received her Doctorate of Medicine from Case Western Reserve University School of Medicine in Cleveland, OH. Dr. Shelly has been practicing Primary Care and Obesity medicine since 2014. In 2017, she became a Diplomat of the American Board of Obesity Medicine. She is the lead physician at the Wellstar Medical Center Douglasville. She started a weekly podcast & Youtube channel entitled Back on Track: Achieving Healthy Weight loss, where she discusses how to get on track and stay on track with your weight loss journey. She has spoken for numerous local and national organizations, including the Obesity Medicine Association, and the Georgia Chapter of the American Society of Metabolic and Bariatric Surgeons. She has been featured on CNN, Fox 5 News, Bruce St. James Radio show, Upscale magazine, and Shape.com. She was named an honoree of the 2021 Atlanta Business Chronicle's 40 under 40 award. She also is a collaborating author for the, "Made for More: Physician Entrepreneurs who Live Life and Practice Medicine on their own terms''. Resources: FREE! Discover the 5 Reasons Your Weight-Loss Journey Has Gotten Derailed (And How To Get Back On Track!)
Free course: Improve your metabolic healthGet our free email course on how glucose, nutrition, exercise, sleep, and measurement can help you build habits that support better energy and long-term health: https://levels.link/wnlWhat are GLP-1 drugs actually doing in the body, who are they for, and why might some people want to think twice before treating them like a six-month shortcut?For years, obesity treatment focused largely on behavior: eat less, move more, stay motivated. Yet many people lost weight only to regain it. According to obesity medicine pioneer Dr. Robert Kushner, that wasn't a failure of willpower. It was a failure to fully understand the biology driving weight regulation.In this episode of A Whole New Level, Mike Haney sits down with Kushner, one of the leading figures in obesity medicine and a lead investigator on the landmark STEP trials, to discuss how GLP-1 medications are changing the field. He explains why these drugs may be the first treatments capable of helping patients “fight biology with biology,” why appetite regulation appears to work differently in different people, and why many patients describe a dramatic reduction in food noise after starting treatment.But this conversation goes beyond how the drugs work. Kushner also addresses one of the biggest questions facing obesity medicine today: who should actually take these medications? He explains why obesity specialists evaluate far more than a number on the scale, why someone hoping to lose a modest amount of weight may want to think carefully before pursuing treatment, and why successful long-term health still requires changes that no medication can provide.They also discuss obesity as a disease, the promise and limitations of telehealth prescribing, and why maintaining weight loss often requires something deeper than motivation: a shift in identity.
Send us Fan MailFructose survival hypothesis: how fructose metabolism in the liver triggers ATP depletion, uric acid production, oxidative stress, lipogenesis & leptin resistance.TOPICS DISCUSSED:Glucose vs Fructose Metabolism: Fructose is rapidly metabolized in the liver by fructokinase without feedback, causing ATP depletion and uric acid production, unlike glucose metabolism.Liver Effects: Fructose induces uric acid production, NADPH oxidase activation, mitochondrial oxidative stress, and de novo lipogenesis even under caloric restriction.Fructose Survival Hypothesis: Fructose signaling promotes fat storage, leptin resistance, foraging behavior, and metabolic syndrome as adaptations for hibernation or starvation, including metabolic water production.Brain Impacts: Endogenous fructose production from glucose (polyol pathway) triggered by high glucose, salt, or stress leads to insulin resistance, mitochondrial damage, and neuroinflammation in Alzheimer's-vulnerable regions.Evolutionary Context: Human uricase mutation ~12 million years ago enhanced fructose effects for fat storage during seasonal starvation but increases vulnerability today.Modern Triggers: Added sugars, high fructose corn syrup, salt-sugar combinations, and omega-6 fats synergize with fructose to amplify inflammation, appetite, and disease risk.Alzheimer's Link: Fructose-driven brain changes mirror Alzheimer's pathology, with high brain fructose in patients and potential for fructokinase inhibitors as therapy.ABOUT THE GUEST: Richard Johnson MD, is a professor of medicine who has conducted clinical practice and NIH-funded research on sugar metabolism since the late 1990s. His work focuses on the role of fructose in metabolic syndrome, obesity, and related diseases.RELATED CONTENT:Article | Dietary Fructose & Metabolic Health: An Evolutionary PerspectiveM&M 249: Fructose, Microglia, Anxiety & Brain Development | Justin Perry | 249Support the showHealth Products by M&M Partners:AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models.OmegaQuant: At-home blood testing to see fatty acid profiles, including omega-3 fatty acids. Use link to see options and support M&M.SiPhox Health: Comprehensive, cost-effective bloodwork from the comfort of home. Use code TRIKOMES for 20% off.KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime)SporesMD: Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off.For all the ways you can support my efforts
Episode 4136 │ June 2, 2026 Dr. Joel Wallach reveals why obesity, diabetes, and metabolic syndrome are nutritional deficiency diseases — and why medicine profits from keeping you sick. In this featured presentation, veterinarian and physician Dr. Joel Wallach delivers his landmark Hell's Kitchen talk — a systematic breakdown of why obesity, type 2 diabetes, and metabolic syndrome are not genetic failures or lifestyle weaknesses, but predictable outcomes of mineral-depleted food and a medical system with no financial incentive to cure what it can manage. Wallach draws on four decades of animal and human research, including 17,500 autopsies across 454 species, to show that the same nutritional formulas that eliminated disease in livestock apply directly to human metabolism. He traces the collapse of dietary minerals to the modern electric kitchen, documents USDA data showing catastrophic nutrient loss in American food from 1975 to 2004, and explains the suppressed 1957 discovery that adult onset type 2 diabetes can be prevented and reversed with two trace minerals. He also dismantles the conventional warnings on salt, cholesterol, eggs, and exercise — and profiles the common traits of people who live well past 100. What is Hell's Kitchen — and how did the modern electric stove trigger a cascade of metabolic disease in America? What causes obesity and type 2 diabetes at the nutritional level, and why have doctors ignored the cure since 1957? Why do the longest-lived people on earth share low carbohydrate intake and daily mineral replenishment? Does salt cause high blood pressure — what does the government's own sodium study actually conclude? Why have professional athletes never lived to 100, while sedentary people routinely do? BardsFM is a daily independent podcast covering faith, liberty, history, and information warfare. Hosted by Scott Kesterson — combat veteran, documentary filmmaker, and rancher. Over 4,100 episodes and 50 million lifetime downloads. New episodes every weekday. bards.fm #BardsFM_HealthAndWellness #WholeBodyHealth #Nutrification Bards Nation Health Store: www.bardsnationhealth.com MYPillow promo code: BARDS >> Go to https://www.mypillow.com/bards and use the promo code BARDS or... Call 1-800-975-2939. EMPShield protect your vehicles and home. Promo code BARDS: Click here Treadlite Broadforks...best garden tool EVER. Promo code BARDS26: TreadliteBroadforks.com EnviroKlenz Air Purification, promo code BARDS to save 10%: www.enviroklenz.com Morning Intro Music Provided by Brian Kahanek: www.briankahanek.com Founders Bible 20% discount code: BARDS >>> TheFoundersBible.com Windblown Media 20% Discount with promo code BARDS: windblownmedia.com White Oak Pastures Grassfed Meats, Get $20 off any order $150 or more. Promo Code BARDS: www.whiteoakpastures.com/BARDS Mission Darkness Faraday Bags and RF Shielding. Promo code BARDS: Click here If you wish to support this podcast directly you can donate here... DONATE: Click here Mailing Address: Xpedition Cafe, LLC Attn. Scott Kesterson 591 E Central Ave, #740 Sutherlin, OR 97479
Throwback Thursday (Originally aired: 6/9/25)This week, Bunnie brings on her personal doctor and friend, Dr. Leah Cordovez - a calm, no-BS physician who blends science and nature to actually know her patients. They talk about Dr. C's wild journey from Panama to private practice, what it's like treating Bunnie's weekly “emergencies,” and why the bond between doctor and patient matters more than we think. Dr. C also answers your questions about sleep, endometriosis, weight, poop (yes, really), and how to actually feel better without shame, shortcuts, or guesswork.Dr. Cordovez: Be WellWatch Full Episodes & More: YouTubeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Episode 2806 - Vinnie Tortorich and Chris Shaffer discuss grip strength, rising rates of cancer in people under 50, childhood obesity, and more. https://vinnietortorich.com/2026/05/rising-rates-of-cancer-episode-2806 PLEASE SUPPORT OUR SPONSORS Pure Vitamin Club Pure Coffee Club NSNG® Foods VILLA CAPPELLI EAT HAPPY KITCHEN YOU CAN WATCH THIS EPISODE ON YOUTUBE - @FitnessConfidential Podcast Vinnie's workout videos are available to purchase! Choose from a 2-day, 4-day, or 6-day workout–or buy all three at a discount! TO PURCHASE VINNIE'S WORKOUT VIDEOS, CLICK THIS LINK: https://vinnietortorich.com/workout Rising Rates of Cancer Keeping strength up as you age is important. (10:40) Grip strength can be an indicator of health, and it can be measured. Why not do something simple that will help your strength? Obesity is a large driver in increasing cancer rates in people under 50 years of age, especially colon cancers. (28:00) Exercise improves certain biomarkers in kids. (33:33) Parents can help at home by keeping junk food out of the house, but ultimately, kids need to decide for themselves. Speaking negatively to them about weight issues can cause different problems. Carbs like bread, pasta, and grains can cause weight gain, even when keeping below a caloric range. (44:00) Calories in, calories out is not the end-all, be-all. Even eating low-carb can cause you to gain weight if you're adding too much to a meal. (46:00) Do not think you can pound even healthy food and not gain weight. A vast number of nutritional studies have been conducted, but not in humans; consequently, findings from studies in mice do not necessarily translate to humans. (54:00) Charitywatch.org is a good place to see where your money will have the most impact. https://www.charitywatch.org The NSNG® VIP GROUP IS NOW CLOSED AGAIN AS OF SUNDAY, MARCH 15TH Anna's next cookbook, Eat Happy Cocktail Hour, is filled with cocktails, mocktails, and appetizers and is available for pre-order right now. If you pre-order, you'll get bonus goodies! You can preorder from a wide variety of booksellers at https://eathappycocktailhour.com/ Save your receipt from wherever you preorder, you'll need it for your bonuses! Physical Release Date is October 2026 A New Sponsor Jaspr Air Scrubbers has a discount code, VINNIE, that gets you $200 off for a limited time. Jaspr offers a lifetime warranty. Go to Jaspr.co for more information or to purchase. (1:05:00) You can book a consultation with Vinnie to get guidance on your goals. https://vinnietortorich.com/phone-consultation-2/ More News Serena has added some of her clothing suggestions and beauty product suggestions to Vinnie's Amazon Recommended Products link. Self Care, Beauty, and Grooming Products that Actually Work! https://www.amazon.com/shop/vinnietortorich/list/3GPVU29UHHPMY?ref_=aipsflist Don't forget to check out Serena Scott Thomas on Days of Our Lives on the Peacock channel. "Dirty Keto" is available on Amazon! You can purchase or rent it here.https://amzn.to/4d9agj1 Please make sure to watch, rate, and review it! Eat Happy Italian, Anna's second cookbook, is available! You can go to https://eathappyitalian.com You can order it from Vinnie's Book Club. https://amzn.to/3ucIXm Anna's recipes are in her cookbooks, on her website, and on Substack —they will spice up your day! https://annavocino.substack.com/ PURCHASE DIRTY KETO (2024) The documentary launched in August 2024! Order it TODAY! This is Vinnie's fourth documentary in just over five years. Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries Then, please share my fact-based, health-focused documentary series with your friends and family. Additionally, the more views it receives, the better it ranks, so please watch it again with a new friend! REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! PURCHASE BEYOND IMPOSSIBLE (2022) Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries FAT: A DOCUMENTARY 2 (2021) Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries FAT: A DOCUMENTARY (2019) Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries