Podcasts about Obesity

Medical condition in which excess body fat harms health

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    Best podcasts about Obesity

    Show all podcasts related to obesity

    Latest podcast episodes about Obesity

    Conspirituality
    300: Farming Ballerinas

    Conspirituality

    Play Episode Listen Later Mar 19, 2026 56:22


    When Hannah and Daniel Neeleman recently went on camera to explain their position on raw milk, they assured their 22 million-plus following that they were going to follow regulations—with a bit of a grudge. The couple behind Ballerina Farm wasn't going to let a little bacteria get in the way of their farming operations, so they'll just focus on pasteurized products. While not associated with MAHA, some of their takes on health certainly rhyme. So today we'll get into this uber-popular feed: who they are, what they're doing in the mountains of Utah, and how privilege plays out in farming and childbearing aesthetics. Show Notes Is Hannah Neeleman Mormon? Inside Ballerina Farm's Religion After Lifestyle Controversy The story of Ballerina Farm and the 2 co-CEOs behind it Meet the queen of the ‘trad wives' (and her eight children) Why influencers with 7, 8, or 10 kids are having a moment The Trad-Wife Revolution Is Upon Us Ballerina Farm pauses raw milk sales after samples fail health tests Ballerina Farm's Hannah Neeleman explains the dairy's decision to stop selling raw milk JetBlue's Founder Helped Fund A Stanford Study That Said The Coronavirus Wasn't That Deadly Hannah Neeleman's “Viral” Glowy Skin Secret You'll Never Really Know Ballerina Farm Postpartum Weight Retention Risk Factors and Relationship to Obesity at One Year - PMC Effect of grand multiparity on adverse maternal outcomes: A prospective cohort study Are tradwives and feminists two sides of the same coin on women's labor? | KUER  Tia Levings on Fundie Parenting  Number of siblings and intellectual development. The resource dilution explanation - PubMed WAGES AGAINST HOUSEWORK | caring labor  Learn more about your ad choices. Visit megaphone.fm/adchoices

    Intelligent Medicine
    Understanding Metabolic Dysfunction: A Deep Dive with Dr. Bret Scher, Part 1

    Intelligent Medicine

    Play Episode Listen Later Mar 17, 2026 30:14


    Dr. Bret Scher, medical director of the Coalition for Metabolic Health, discusses making metabolic health the foundation of medicine amid rising obesity and type 2 diabetes and reports that 93% of Americans have suboptimal metabolic health. Scher defines metabolic health using markers including glucose, insulin, triglycerides, HDL, blood pressure, and waist size, and cites evidence linking insulin resistance to heart disease, stroke, cancer, psychiatric illness, and other complications. They discuss simple self- and lab-assessments (waist-to-height ratio, fasting insulin with glucose/HOMA-IR, triglyceride-to-HDL ratio, CGMs). Scher critiques the Eat Lancet report for assuming one optimal diet, reliance on low-quality nutrition epidemiology, potential nutrient shortfalls, and environmental oversimplification, while supporting newer dietary guidelines that allow lower-carb approaches. Part two covers contradictory nutrition studies, distinctions between low-carb and ketogenic diets, emerging “metabolic psychiatry” and ketogenic therapy for mental illness and cognitive decline, limits and rebound risks of GLP-1 drugs, and Coalition efforts to improve school food and influence policy.

    The Curbsiders Internal Medicine Podcast
    #517 DIGEST: Weight regain after weight loss medications, GLP1/GIP comparisons, valacyclovir for Alzheimer's, and nudges to encourage deprescribing

    The Curbsiders Internal Medicine Podcast

    Play Episode Listen Later Mar 16, 2026 65:41


    Join us as we review and appraise recent practice-changing articles. In this episode, we cover the latest in GLP-1s and GIP agonists for CVD, Type 2 Diabetes, and Obesity, valacyclovir to treat Alzheimer's, weight regain patterns after medication-induced weight loss, and a deep dive into the data behind deprescribing – and behavioral science to increase deprescribing behavior.  Fill your brain hole with a delicious stack of hotcakes! Featuring Paul Williams (@PaulNWilliamz), Alex Chaitoff (@alexchaitoff), Nora Taranto (@norataranto), & Matt Watto (@doctorwatto).Claim CME for this episode at curbsiders.vcuhealth.org!Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CMECredits Written and Hosted by: Nora Taranto MD, MSCE; Alexander Chaitoff MD, MPH; Paul Williams, MD, FACP,, & Matthew Watto MD, FACP Cover Art: Nora Taranto MD, MSCE Reviewer: Sai S Achi MD, MBA, FACP Technical Production: Pod Paste Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP Show Segments Intro, disclaimer GLP-1 + GIPs vs GLP-1s for patients with T2DM and Obesity – SURPASS-CVOT  Weight Regain after Weight loss  VALAD – Valacyclovir in patients with early Alzheimer's  Nudges to increase Deprescribing  Outro Sponsor: MedStudy Qbank Study less. Remember more. Pass confidently.Medstudy.com/CurbsidersCURB15 for 15% offSponsor: FIGSWe've teamed up with FIGS, and now Curbsiders listeners can get 15% off at Wearfigs.com with code FIGSRX. Sponsor: QuinceRight now, go to Quince.com/curb for free shipping and 365-day returns. Sponsor: A Dangerous DiagnosisTo get 20% off use DIAGNOSIS20 at www.penguinrandomhouse.com/books/808848/a-dangerous-diagnosis-by-shantanu-rai/paperback/

    Back on Track: Overcoming Weight Regain
    Episode 232: Five Things You Need to Know About the New Wegovy Pill

    Back on Track: Overcoming Weight Regain

    Play Episode Listen Later Mar 16, 2026 10:20


    You've heard about the Wegovy shot. Now there's a pill — and the confusion is already spreading. Is it the same? Does it work as well? Can you take it with your other medications? In December, the FDA approved an oral form of semaglutide specifically for weight management and cardiovascular risk reduction. That's a game-changer — but only if you know how to use it correctly. Take it wrong and it won't work at all. In this episode, I will break down the five things you need to know about the new Wegovy pill. I will talk about the science behind SNAC technology, why this medication goes beyond weight loss, and what are the side effects to expect If you or someone you love is exploring weight loss medication options, this episode gives you the clarity to have a smarter conversation with your doctor. Listen now! Episode Highlights: Why the timing and conditions of how you take this pill are non-negotiable The science behind SNAC technology and why this pill can't just be swallowed with breakfast Why this medication goes beyond weight loss and also protects your heart What to do if you're already taking levothyroxine or other empty-stomach medications What side effects to expect,  and how much weight loss to realistically anticipate Connect with Dr. Alicia Shelly: Website | drshellymd.com Facebook | www.facebook.com/drshellymd Instagram | @drshellymd Linked In | www.linkedin.com/in/drshellymd Twitter | @drshellymd About Dr. Alicia Shelly Dr. Alicia Shelly was raised in Atlanta, GA. She received her Doctorate of Medicine from Case Western Reserve University School of Medicine in Cleveland, OH.  Dr. Shelly has been practicing Primary Care and Obesity medicine since 2014.  In 2017, she became a Diplomat of the American Board of Obesity Medicine. She is the lead physician at the Wellstar Medical Center Douglasville. She started a weekly podcast & Youtube channel entitled Back on Track: Achieving Healthy Weight loss,  where she discusses how to get on track and stay on track with your weight loss journey. She has spoken for numerous local and national organizations, including the Obesity Medicine Association, and the Georgia Chapter of the American Society of Metabolic and Bariatric Surgeons. She has been featured on CNN, Fox 5 News, Bruce St. James Radio show, Upscale magazine, and Shape.com. She was named an honoree of the 2021 Atlanta Business Chronicle's 40 under 40 award. She also is a collaborating author for the, "Made for More: Physician Entrepreneurs who Live Life and Practice Medicine on their own terms''.   Resources: FREE! Discover the 5 Reasons Your Weight-Loss Journey Has Gotten Derailed (And How To Get Back On Track!)

    Wellness Talk with George Batista
    The Meal Timing Secret for Heart and Metabolic Health

    Wellness Talk with George Batista

    Play Episode Listen Later Mar 15, 2026 48:18


    What if the timing of your meals matters just as much as what you eat? In this episode, we explore emerging research suggesting that eating fewer meals—and cutting out late-night snacks—may help protect against Type 2 Diabetes and Obesity, while also improving gut and heart health.We break down new findings on why closing the kitchen earlier in the evening could help your body reset overnight. From metabolic signals to hormone balance, we discuss how simple habits—like stopping food intake at least three hours before bed—may support your cardiovascular system and optimize digestion.You'll also hear about the science behind the Leptin Diet, including how the hormone Leptin helps regulate hunger, metabolism, and energy balance. We review new research that reinforces the core principles of the leptin-focused approach to eating, including meal timing, reduced snacking, and supporting metabolic signaling.Finally, we take a closer look at The Leptin Control Pack, a nutritional support system designed to enhance thyroid and leptin function, and discuss how supplements may complement lifestyle strategies aimed at improving metabolic health.If you're curious about how meal timing, hormone balance, and metabolic science intersect, this episode offers practical insights and the latest research to help you rethink when—and how often—you eat.http://www.myvitaminresource.com/https://www.georgebatista.com/

    PBS NewsHour - Full Show
    The promise of obesity drugs and their potential risks

    PBS NewsHour - Full Show

    Play Episode Listen Later Mar 13, 2026 25:12


    Once a relatively obscure class of drugs used for people with diabetes, GLP-1s have now shown an impressive ability to treat obesity, which affects over 100 million Americans. Horizons moderator William Brangham explores the great promise of the drugs and the potential concerns surrounding them with Dr. Jody Dushay, Dr. Rekha B. Kumar, Dr. Anna Lembke and Dr. Ziyad Al-Aly. PBS News is supported by - https://www.pbs.org/newshour/about/funders. Hosted on Acast. See acast.com/privacy

    Burn it Nutrition Podcast
    Ep197: Weight-Loss Injection Era: Are We Solving Obesity… or Avoiding the Real Problem? W/Dr. John Lewis

    Burn it Nutrition Podcast

    Play Episode Listen Later Mar 13, 2026 58:40


    ●       The cultural rise of weight-loss injections ●       The promise vs. the reality of rapid weight loss ●       The root causes of weight gain medications don't address ●       Foundational habits for safe, sustainable weight loss ●       A surprising approach to dementia and chronic inflammation ●       And so much more!   Links mentioned in this episode! Show notes page: https://burnitnutrition.com/podcast197/ . . Get up to 15% off Magnesium Breakthrough when you order at https://bioptimizers.com/burnit  . . LMNT Sparkling Can – Get a free sample pack with your first order – https://drinklmnt.com/burnit . Learn more about Dr. John Lewis: Website: https://drlewisnutrition.com/ . . Podcast Shop Page for Best Deals at https://burnitnutrition.com/shop  . Leave me a rating & review on Apple Podcasts: https://itunes.apple.com/us/podcast/burn-it-nutrition-podcast/id1195955730?mt=2  . Follow Joseph Navarro on Instagram under @BurnitNutrition . Follow Joseph Navarro on Facebook under @BurnitNutrition . Thank You for Listening!! Please share this episode! Be the one who helps spark a transformation in your family! Feedback to share? Send email to info@BurnitNutrition.com Subscribe! Don't miss another episode! Notice of Sponsorship Affiliate Disclosure with BiOptimizers, LMNT,  Fair Use Disclaimer The following podcast episode contains audio clips that are used under the doctrine of fair use as defined by United States copyright law. These clips are used for purposes of commentary, criticism, news reporting, teaching, scholarship, and research. All rights to the original audio content remain with the respective copyright holders. This use is not intended to infringe upon their rights, but to enhance the discussion and understanding of the topic at hand. Please read the full medical disclaimer  burnitnutrition.com/medical-disclaimer/

    Mind & Matter
    Obesity Resistance & Leanness | Ep. 284

    Mind & Matter

    Play Episode Listen Later Mar 13, 2026 60:00


    Send a textBiology of obesity resistance and factors influencing weight gain in humans and animals.TOPICS DISCUSSED:Historical views on obesity: In some cultures, like northern Africa or Stone Age societies, high body fat signaled status or attractiveness due to food scarcity, unlike today's focus on leanness amid calorie abundance.Energy balance components: Metabolizable energy (95% absorption on average, but varying 1-11%) and unabsorbed nutrients excreted as waste significantly influence weight.Obesity resistance in animals: Inbred mouse strains show wide variation in weight gain on high-fat diets, often somewhat uncoupled from overeating, suggesting roles for feed efficiency, energy expenditure, or waste rather than intake alone.Genetic & twin studies: Monozygotic twins overfed 1,000 extra calories daily vary widely in weight gain (4-13 kg), indicating genetic influences, while mouse litter size affects lifelong obesity propensity via early-life programming.Bloodborne factors & hormones: Parabiosis studies led to leptin's discovery for defending against weight loss, but evolutionary logic suggests systems also prevent excess gain, though modern environments may weaken this.Human thinness research: Constitutionally thin people snack more, move less, yet have better cardiometabolic health, but we don't yet understand why.GLP-1 drugs & future directions: These slow gut transit and suppress appetite, but obesity's root causes remain unclear; emerging thinness studies could inform prevention beyond drugs.ABOUT THE GUEST: Jens Lund, PhD is a postdoctoral researcher at the University of Copenhagen's Novo Nordisk Foundation Center for Basic Metabolic Research.RELATED EPISODE:M&M 132 | Obesity Epidemic, Diet, Metabolism, Saturated Fat vs. PUFAs, Energy Expenditure, Weight Gain & Feeding Behavior | John SpeakmanSupport the showHealth Products by M&M Partners: SporesMD: Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off. Lumen device: Optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off. AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models. Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) For all the ways you can support my efforts

    PBS NewsHour - Science
    The promise of obesity drugs and their potential risks

    PBS NewsHour - Science

    Play Episode Listen Later Mar 13, 2026 25:12


    Once a relatively obscure class of drugs used for people with diabetes, GLP-1s have now shown an impressive ability to treat obesity, which affects over 100 million Americans. Horizons moderator William Brangham explores the great promise of the drugs and the potential concerns surrounding them with Dr. Jody Dushay, Dr. Rekha B. Kumar, Dr. Anna Lembke and Dr. Ziyad Al-Aly. PBS News is supported by - https://www.pbs.org/newshour/about/funders. Hosted on Acast. See acast.com/privacy

    Aging-US
    BSO Recapitulates Anti-Obesity Effects of Sulfur Amino Acid Restriction Without Bone Loss

    Aging-US

    Play Episode Listen Later Mar 13, 2026 3:05


    BUFFALO, NY — March 13, 2026 — A new #research paper was #published in Volume 18 of Aging-US on March 2, 2026, titled “D, L-Buthionine-(S, R)-sulfoximine recapitulates the anti-obesity effects of sulfur amino acid restriction without the associated deleterious effects on bone in male mice.” Led by Naidu B. Ommi from the Orentreich Foundation for the Advancement of Science — with corresponding author Sailendra N. Nichenametla from the same institution — the study tests whether the glutathione (GSH)-lowering compound D, L-buthionine-(S, R)-sulfoximine (BSO) reproduces the anti-obesity effects of sulfur amino acid restriction (SAAR) without causing the bone loss seen with SAAR diets. Using diet-induced obese male C57BL6/NTac mice fed high-fat diets, the authors compared: a control methionine-replete diet, a SAAR diet (low methionine, no cysteine), SAAR plus the GSH precursor N-acetylcysteine (NAC), and control diet plus BSO in drinking water. Using body-composition, micro-CT, histomorphometry, and biomechanical testing, the team confirmed prior work that SAAR reduces body fat but also lowers trabecular and cortical bone mineral density, increases marrow adiposity, reduces osteoblast numbers, and weakens bone biomechanical strength. Crucially, while NAC supplementation reversed the bone defects of SAAR (implicating cysteine/glutathione restriction in bone loss), BSO reproduced the lean, anti-obesity phenotype without producing the deleterious bone effects observed in SAAR mice. In short, BSO recapitulated the anti-obesity benefits of SAAR without causing the same bone loss — a finding with potential relevance to developing anti-obesity strategies that avoid skeletal harm. “Despite its anti-obesity effects, BSO did not exert any detrimental effects on bones.” The authors emphasize next steps and caveats. They call for mechanistic studies to define how GSH lowering drives fat loss yet spares bone under BSO treatment, investigations of age-at-onset, tissue-specific, and sex-specific effects, and long-term safety studies to assess off-target or delayed adverse effects of BSO before any clinical development. The paper frames BSO as a promising tool compound to dissect the beneficial versus deleterious axes of sulfur amino acid biology, but not yet as a human therapy without further preclinical evaluation. DOI - https://doi.org/10.18632/aging.206358 Corresponding author - Sailendra N. Nichenametla - snichenametla@orentreich.org Abstract video - https://www.youtube.com/watch?v=0adFA_b-q1Q Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206358 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - bone, aging, methionine, glutathione, redox To learn more about the journal, please visit https://www.Aging-US.com​​ and connect with us on social media at: Bluesky - https://bsky.app/profile/aging-us.bsky.social ResearchGate - https://www.researchgate.net/journal/Aging-1945-4589 X - https://twitter.com/AgingJrnl Facebook - https://www.facebook.com/AgingUS/ Instagram - https://www.instagram.com/agingjrnl/ LinkedIn - https://www.linkedin.com/company/aging/ Reddit - https://www.reddit.com/user/AgingUS/ Pinterest - https://www.pinterest.com/AgingUS/ YouTube - https://www.youtube.com/@Aging-US Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

    Diabetes Core Update
    Special Edition: Understanding Chronic Kidney Disease in People with Diabetes — Epidemiology, Pathophysiology, and Detection - March 2025

    Diabetes Core Update

    Play Episode Listen Later Mar 12, 2026 26:34


    In this special edition on Obesity as a Chronic Disease our host, Dr. Neil Skolnik will discuss epidemiology, pathophysiology and screening for CKD in People with Diabetes. This special episode is supported by an independent educational grant from Bayer. Presented by: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health Holly Kramer, M.D., Professor of Public Health Sciences and Medicine in the Division of Nephrology and Hypertension at Loyola University Chicago, past-president of the National Kidney Foundation, Editor-in-Chief of the National Kidney Foundation's journal,  Advances in Kidney Disease and Health (AKDH).   Selected references: Chronic Kidney Disease and Risk Management: Standards of Care in Diabetes—2026 . The American Diabetes Association's Standards of Care 2026, Diabetes Care 2026;49 (Supplement_1) :S246–S260  

    Dr. Baliga's Internal Medicine Podcasts
    Obesity, Immunity, Cancer

    Dr. Baliga's Internal Medicine Podcasts

    Play Episode Listen Later Mar 12, 2026 6:23


    Obesity is not simply excess weight—it is a metabolic and inflammatory state that can reshape cancer biology. Adipose tissue alters hormones, insulin signaling, inflammatory cytokines, and immune responses, creating conditions that favor tumor development. Evidence now links obesity with cancers of the breast, colon, endometrium, pancreas, liver, kidney, and esophagus. Understanding these mechanisms opens the door to precision prevention strategies, from weight management to metabolic therapies. The message from translational science is clear: metabolism and malignancy are deeply intertwined. #CancerResearch #ObesityScience #TranslationalMedicine

    The Fat Doctor Podcast
    Disease Mongering: Inventing Illness To Sell A Cure

    The Fat Doctor Podcast

    Play Episode Listen Later Mar 11, 2026 34:24 Transcription Available


    Send a textDisease mongering has transformed human body diversity into a medical crisis requiring pharmaceutical intervention. When Ray Moynihan wrote that "there's a lot of money to be made from telling healthy people they're sick," he exposed a corporate strategy that reaches its most devastating form in the creation of "ob*sity" as a disease. This wasn't accidental harm caused while trying to help people - this was intentional pathologization of natural human variation, funded by pharmaceutical companies and legitimized through corrupt alliances between industry, doctors, and supposed patient advocacy groups. In this episode, I expose how the disease creation itself causes harm separate from any treatment: social exclusion, healthcare denial, psychological trauma, economic exploitation, and the erosion of bodily autonomy. We created a disease whose only "treatment" doesn't work and causes the very harms we attribute to the disease. They didn't just gnaw away at our self-confidence—they gnawed away at our right to exist. Moynihan, Ray, Iona Heath, and David Henry. ‘Selling Sickness: The Pharmaceutical Industry and Disease Mongering'. BMJ : British Medical Journal 324, no. 7342 (2002): 886–91. https://doi.org/10.1136/bmj.324.7342.886.Got a question for the next podcast? Let me know! Connect With Me WEEKLY NEWSLETTER: Get a free script when you sign up THE WEIGHTING ROOM: Community with a neurodivergent flavour. **BOOK CLUB** exclusive to Weighting Room members. CONSULTATION: For the ultimate transformation in your healthcare journey MASTERCLASS LIBRARY: Become an expert in your condition and the weight inclusive ways to manage it FREE GUIDES:Evidence-based, not diet nonsense Find me on Instagram, YouTube, and LinkedIn.

    Podcast Notes Playlist: Latest Episodes
    Andrew Huberman: Peptides, Sleep Tech, and the End of Obesity

    Podcast Notes Playlist: Latest Episodes

    Play Episode Listen Later Mar 11, 2026


    A16z Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Daisy Wolf speaks with Dr. Andrew Huberman, professor of neurobiology and ophthalmology at Stanford University and host of the Huberman Lab podcast. They discuss how the pandemic sparked a consumer health revolution, the emerging peptide and GLP landscape, what the science actually says about focus drugs, and the neurotechnologies Huberman believes will let us write to our own biology within the next five years.   Resources: Follow Andrew Huberman on X: https://twitter.com/hubermanlab Follow Daisy Wolf on X: https://twitter.com/daisydwolf Stay Updated:Find a16z on YouTube: YouTubeFind a16z on XFind a16z on LinkedInListen to the a16z Show on SpotifyListen to the a16z Show on Apple PodcastsFollow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

    ASHPOfficial
    Clinical Conversations: CE: Scaling Up Obesity Care: Pharmacists, CPAs, and Clinic Success (CE)

    ASHPOfficial

    Play Episode Listen Later Mar 11, 2026 30:04


    This podcast discusses how pharmacists are expanding their roles in obesity management through collaborative practice agreements (CPAs) and innovative clinic workflows. Guests share their experiences launching and sustaining weight management services, highlighting operational considerations and billing strategies. Listeners will gain practical insights into establishing pharmacist-led obesity care models and supporting patients in achieving long-term success. The information presented during the podcast reflects solely the opinions of the presenter. The information and materials are not, and are not intended as, a comprehensive source of drug information on this topic. The contents of the podcast have not been reviewed by ASHP, and should neither be interpreted as the official policies of ASHP, nor an endorsement of any product(s), nor should they be considered as a substitute for the professional judgment of the pharmacist or physician.

    BioSpace
    Prasad Out at FDA, Lawmaker Takes Action on Rare Disease Rejections and a Spate of Obesity Data

    BioSpace

    Play Episode Listen Later Mar 11, 2026 28:12


    After Friday's news that Center for Biologics Evaluation & Research Chief Vinay Prasad will leave the FDA—again—at the end of April, stocks for several rare disease drug developers popped. UniQure, in particular, was up 51% in premarket trading on Monday. Prasad in a meeting last Thursday with select journalists called the biotech's Huntington's treatment AMT-130 a “failed” therapy, according to STAT News. Shares of Replimune and REGENXBIO—which have suffered rejections during the past year—also rose.One person who is not impressed with the plethora of rare disease drug rejections of late—H.C. Wainwright said in a note Tuesday that there have been at least five cell and gene therapies they believe could have been approved under prior FDA officials—is Wisconsin Senator Ron Johnson. Tuesday, Bloomberg News reported that Johnson has launched an investigation into these recent denials.Johnson called the FDA's request that uniQure conduct a sham surgery-controlled trial of AMT-130 “bureaucratic idiocy,” according to the publication. Meanwhile, uniQure and the FDA appear to be on different pages regarding the design of this prospective trial, with uniQure Chief Medical Officer Walid Abi-Saab referring to a 10-12 hour surgery during which [burr] holes would be drilled in patients' skulls and Prasad claiming on a media call last week that it would require only “one to three nicks in the scalp.”In other news, no episode of The Weekly would be complete without our weekly weight loss segment. Roche and Zealand Pharma's amylin analog fell short of Eli Lilly's rival candidate eloralintide; AbbVie reported what analysts called “competitive” results, with its amylin analog eliciting nearly 10% weight loss at 13 weeks in a Phase 1 trial; and Regeneron touted a much-needed Phase 3 win for Hansoh-partnered dual GLP-1/GIPR agonist olatorepatide in China. Beyond data, Novo Nordisk and Hims & Hers are together again, with Novo striking a deal to sell its injectable and oral GLP-1 medicines through the telehealth provider.Elsewhere on the business side of biopharma, experts are reporting a cut-throat atmosphere behind doors on the M&A front as the supply of companies available to buy dwindles.

    a16z
    Andrew Huberman: Peptides, Sleep Tech, and the End of Obesity

    a16z

    Play Episode Listen Later Mar 9, 2026 51:36


    Daisy Wolf speaks with Dr. Andrew Huberman, professor of neurobiology and ophthalmology at Stanford University and host of the Huberman Lab podcast. They discuss how the pandemic sparked a consumer health revolution, the emerging peptide and GLP landscape, what the science actually says about focus drugs, and the neurotechnologies Huberman believes will let us write to our own biology within the next five years.   Resources: Follow Andrew Huberman on X: https://twitter.com/hubermanlab Follow Daisy Wolf on X: https://twitter.com/daisydwolf Stay Updated:Find a16z on YouTube: YouTubeFind a16z on XFind a16z on LinkedInListen to the a16z Show on SpotifyListen to the a16z Show on Apple PodcastsFollow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

    JAMA Clinical Reviews: Interviews about ideas & innovations in medicine, science & clinical practice. Listen & earn CME credi

    Overweight and obesity may cause 10% of new cancer diagnoses annually in the US. In this JAMA Review in the Translational Science series, author Neil Iyengar, MD, of Emory University discusses the biological pathways that may promote cancer in people with overweight or obesity and potential therapies with JAMA Deputy Editor Mary McDermott, MD. Related Content: Obesity and Cancer

    Bio Eats World
    Andrew Huberman: Peptides, Sleep Tech, and the End of Obesity

    Bio Eats World

    Play Episode Listen Later Mar 9, 2026 51:32


    Daisy Wolf speaks with Dr. Andrew Huberman, professor of neurobiology and ophthalmology at Stanford University and host of the Huberman Lab podcast. They discuss how the pandemic sparked a consumer health revolution, the emerging peptide and GLP landscape, what the science actually says about focus drugs, and the neurotechnologies Huberman believes will let us write to our own biology within the next five years.   Resources: Follow Andrew Huberman on X: https://twitter.com/hubermanlab Follow Daisy Wolf on X: https://twitter.com/daisydwolf   Stay Updated: If you enjoyed this episode, be sure to like, subscribe, and share with your friends! Find a16z on X: https://twitter.com/a16z Find a16z on LinkedIn: https://www.linkedin.com/company/a16z Listen to the a16z Show on Spotify: https://open.spotify.com/show/5bC65RDvs3oxnLyqqvkUYX Listen to the a16z Show on Apple Podcasts: https://podcasts.apple.com/us/podcast/a16z-podcast/id842818711 Follow our host: https://x.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see http://a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

    The Decibel
    Skinny, Inc. Part 3: Body image in the age of Ozempic

    The Decibel

    Play Episode Listen Later Mar 9, 2026 37:44


    The first episode of Skinny Inc. was all about the science behind GLP-1s, and the second episode was about the business, from the pharmaceutical companies who make GLP-1s to the insurance plans that may or may not cover it. Today, we're exploring how the so-called “Ozempic era,” affects people's mental health. First, business owner Maiyhet Burton tells us how using a GLP-1 has helped her body image. Globe health reporter Kelly Grant details how experts are split on the effect of GLP-1s on weight stigma, and psychotherapist Zoë Bisbing explains how the body positive movement helps her clients. Plus, Tigress Osborn, executive director of the National Association to Advance Fat Acceptance on why the popularity of GLP-1s shows how far we have to go with anti-fat discrimination, and Ary Mahraj and Emily Donahue from the National Eating Disorder Information Centre tell us how people with eating disorders may be impacted by the constant discussions about weight loss. Finally, Dr. Stephen Glazer, Medical Director for the Bariatric Surgical Program at Humber River Hospital in Toronto on how weight stigma can be internalized. You can contact the National Eating Disorders Information Centre at their toll-free helpline at 1-866-NEDIC-20 or visit their website. Questions? Comments? Ideas? E-mail us at thedecibel@globeandmail.com Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

    Back on Track: Overcoming Weight Regain
    Episode 231: What happens when you stop your GLP-1?

    Back on Track: Overcoming Weight Regain

    Play Episode Listen Later Mar 9, 2026 17:38


    If you're on Wegovy, Zepbound, Ozempic, or Mounjaro — and worried about what happens when you stop — this episode is for you. The fear of gaining it all back is real. But weight regain is not inevitable. It's manageable. And I'm going to show you how. "What happens when you stop your GLP-1?" This is one of the most common questions I get in my clinic every single week. It's time I answered it publicly — with science, not fear. In this episode, I break down exactly what happens in your body when you stop your GLP-1, why weight regain happens, and the five pillars you need to protect your results, whether you're stopping by choice or out of necessity. Listen now! Episode Highlights: The physiological reason hunger surges and metabolism slows when you stop GLP-1s  What the SURMOUNT-4 clinical trial tells us about weight regain after stopping Tirzepatide Who is at highest risk for regaining weight  The 5 pillars of weight maintenance: protein, resistance training, carb awareness, appetite retraining, and medication transition strategy Connect with Dr. Alicia Shelly: Website | drshellymd.com Facebook | www.facebook.com/drshellymd Instagram | @drshellymd Linked In | www.linkedin.com/in/drshellymd Twitter | @drshellymd About Dr. Alicia Shelly Dr. Alicia Shelly was raised in Atlanta, GA. She received her Doctorate of Medicine from Case Western Reserve University School of Medicine in Cleveland, OH.  Dr. Shelly has been practicing Primary Care and Obesity medicine since 2014.  In 2017, she became a Diplomat of the American Board of Obesity Medicine. She is the lead physician at the Wellstar Medical Center Douglasville. She started a weekly podcast & Youtube channel entitled Back on Track: Achieving Healthy Weight loss,  where she discusses how to get on track and stay on track with your weight loss journey. She has spoken for numerous local and national organizations, including the Obesity Medicine Association, and the Georgia Chapter of the American Society of Metabolic and Bariatric Surgeons. She has been featured on CNN, Fox 5 News, Bruce St. James Radio show, Upscale magazine, and Shape.com. She was named an honoree of the 2021 Atlanta Business Chronicle's 40 under 40 award. She also is a collaborating author for the, "Made for More: Physician Entrepreneurs who Live Life and Practice Medicine on their own terms''. Resources: FREE! Discover the 5 Reasons Your Weight-Loss Journey Has Gotten Derailed (And How To Get Back On Track!)

    Circulation on the Run
    Circulation March 10, 2026 Issue

    Circulation on the Run

    Play Episode Listen Later Mar 9, 2026 24:31


    This week, please join author Michael J. Blaha as he discusses his article "Prospective Associations of Obesity and Obesity Severity With 9 Cardiovascular Outcomes: The Cross Cohort Collaboration." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20260309.22779

    Vet Tales
    Can't Outrun a Bad Diet: Practical Fixes for Pet Obesity

    Vet Tales

    Play Episode Listen Later Mar 5, 2026 30:44 Transcription Available


    In this episode of Vet Tales, Dr. Natalie Brackeen and Dr. Josiah Dame discuss pet obesity—how to recognize it using body condition scores, why excess weight causes arthritis, diabetes, breathing issues and liver problems, and why calories matter more than exercise. They share practical advice for pet caretakers: keep food logs, measure portions, adjust feeding for spayed/neutered and senior pets, consider satiety or weight-loss diets, use meal management tools for multi-pet homes and cats, monitor progress with your veterinarian, and watch for emerging medical options.

    Hit Play Not Pause
    Understanding Midlife Weight Gain, Menopause, and GLP-1s with Diana Reid, MPH, RDN (Episode 264)

    Hit Play Not Pause

    Play Episode Listen Later Mar 4, 2026 74:02


    As women, we're told our bodies are wrong almost from the moment we become aware of them—and that messaging hits hyperdrive when the body composition changes of menopause arrive. Those changes are often framed as urgent health risks, even when the picture is far more nuanced and the steps taken to “fix” them can carry risks of their own. This week we sit down with dietitian and public health nutrition specialist Diana Reid to dig into what actually drives midlife weight gain, what belly fat and BMI do (and don't) mean for your health, and where GLP-1 medications fit into the picture. We talk muscle and bone loss, under-fueling, weight regain, and how to protect your health if you choose to use weight loss medications.Diana Reid is a Registered Dietitian-Nutritionist licensed in both the United States and Luxembourg. She's originally from Seattle, but has been living in Europe since 2016. Diana has a masters degree in Public Health & Nutrition and specializes in nutritional counseling and support for patients with eating disorders; food allergies, intolerances and gut disorders; and the unique challenges related to women's health, especially during midlife and the menopause transition. She is a Certified Intuitive Eating Counselor and follows a non-diet, weight-neutral approach to health and wellness, focusing on habit building, lifestyle behaviors and balanced nutrition. She believes in practicing with compassion, understanding, and a personalized approach to nutrition and well-being. Diana is a married midlife menopausal mom of three teens and a clingy dog, and loves cycling, weight lifting, hiking and traveling. You can find her on social media at @theglobalrd or via her website at www.theglobaldietitian.comResources:Weight Cycling as a Risk Factor for Low Muscle Mass and Strength in a Population of Males and Females with Obesity, hereFull resource list for this episode hereSign up for our FREE Feisty 40+ newsletter: https://feisty.co/feisty-40/Learn More about our 2026 Feisty Events, including Bike Camps and Cycling Trips: https://feisty.co/events/Follow Us on Instagram:Feisty Menopause: @feistymenopauseHit Play Not Pause Facebook Group: https://www.facebook.com/groups/807943973376099Support our Partners:Midi Health: You Deserve to Feel Great. Book your virtual visit today at https://www.joinmidi.com/Hettas: Use code STAYFEISTY for 20% off at https://hettas.com/ Previnex: Get 15% off your first order with code HITPLAY at https://www.previnex.com/ Wahoo: Use the code FEISTY2026 to get a free Headwind Smart Fan (value $300) with the purchase of a Wahoo KICKR RUN at https://shorturl.at/WVhdr

    Focus
    High amounts of sugar found in Nestlé baby cereal sold in Africa

    Focus

    Play Episode Listen Later Mar 4, 2026 5:38


    Swiss food giant Nestlé is facing criticism over the sugar content of Cerelac, its infant cereal brand sold in Africa. An investigation by the NGO Public Eye found that while the product is sold without added sugar in Europe, African versions can contain up to 15 percent sugar.

    Daily Dad Jokes
    World Obesity Day! 65 heavy dad jokes! 04 March 2026

    Daily Dad Jokes

    Play Episode Listen Later Mar 4, 2026 16:21


    Daily Dad Jokes (04 Mar 2026) Christmas Joke Button - 101 eye rolling dad jokes for the festive season! Amazon. The perfect gift for Kris Kringle, Secret Santa and of course for dad! Click here here to view! The official Daily Dad Jokes Podcast electronic button now available on Amazon. The perfect gift for dad! Click here here to view! Email Newsletter: Looking for more dad joke humor to share? Then subscribe to our new weekly email newsletter. It's our weekly round-up of the best dad jokes, memes, and humor for you to enjoy. Spread the laughs, and groans, and sign up today! Click here to subscribe! Listen to the Daily Dad Jokes podcast here: https://dailydadjokespodcast.com/ or search "Daily Dad Jokes" in your podcast app. Jokes sourced and curated from reddit.com/r/dadjokes. Joke credits: xholdsteadyx, TakingAMindwalk, StockInitial4460, Man-e-questions, TommehBoi, SteveBennett64, Kerlandays, TRAKRACER, Masala-Dosage, AndrewMacSydney, iShitSkittles, FrankensteinBionicle, KingPickol, donttakethechip, Upvoter_NeverDie, ChargedBonsai98, boogerknows, Manneqyn, LurkyTheHatMan, tedt93, Chateau512, dipdipbeantot, OpticMoose, KoolaidPower, ilikesidehugs, MewThree1416, Fingerbob73, WrongWayCorrigan-361, fredster2006, FinalCaveat, EndersGame_Reviewer, EmpireStrikes1st, , themoreidont, Obliviouslynormal, Turuu_Was_Taken, kthejoker, kdlaz, boxymcboxbox, Masselein, TheRealThenill, HowManyHaveComeThru, keithasaurus, ilikesidehugs, realinvincibles, eatmystardustsuckers, incredibleinkpen, static612, Ok_Presence36, NoOneLikesJack, porichoygupto, jhn714, Attikey, LastProtagonist, electrocuter666, guamo17, Sjelan, stewithclou, Infectedtoe32, NobleMoistHam, VERBERD, tjeters, VAOkie, dbwebbco, st_jimmy_02, 1989JY_Ked Subscribe to this podcast via: iHeartMedia Spotify iTunes Google Podcasts YouTube Channel Social media: Instagram Facebook Twitter TikTok Discord Interested in advertising or sponsoring our show? Contact us at mediasales@klassicstudios.com Produced by Klassic Studios using AutoGen Podcast technology (http://klassicstudios.com/autogen-podcasts/) Learn more about your ad choices. Visit megaphone.fm/adchoices

    Daily Dad Jokes
    [No Laughter Version] World Obesity Day! 65 heavy dad jokes! 04 March 2026

    Daily Dad Jokes

    Play Episode Listen Later Mar 4, 2026 11:30


    Daily Dad Jokes (04 Mar 2026) Christmas Joke Button - 101 eye rolling dad jokes for the festive season! Amazon. The perfect gift for Kris Kringle, Secret Santa and of course for dad! Click here here to view! The official Daily Dad Jokes Podcast electronic button now available on Amazon. The perfect gift for dad! Click here here to view! Email Newsletter: Looking for more dad joke humor to share? Then subscribe to our new weekly email newsletter. It's our weekly round-up of the best dad jokes, memes, and humor for you to enjoy. Spread the laughs, and groans, and sign up today! Click here to subscribe! Listen to the Daily Dad Jokes podcast here: https://dailydadjokespodcast.com/ or search "Daily Dad Jokes" in your podcast app. Jokes sourced and curated from reddit.com/r/dadjokes. Joke credits: xholdsteadyx, TakingAMindwalk, StockInitial4460, Man-e-questions, TommehBoi, SteveBennett64, Kerlandays, TRAKRACER, Masala-Dosage, AndrewMacSydney, iShitSkittles, FrankensteinBionicle, KingPickol, donttakethechip, Upvoter_NeverDie, ChargedBonsai98, boogerknows, Manneqyn, LurkyTheHatMan, tedt93, Chateau512, dipdipbeantot, OpticMoose, KoolaidPower, ilikesidehugs, MewThree1416, Fingerbob73, WrongWayCorrigan-361, fredster2006, FinalCaveat, EndersGame_Reviewer, EmpireStrikes1st, , themoreidont, Obliviouslynormal, Turuu_Was_Taken, kthejoker, kdlaz, boxymcboxbox, Masselein, TheRealThenill, HowManyHaveComeThru, keithasaurus, ilikesidehugs, realinvincibles, eatmystardustsuckers, incredibleinkpen, static612, Ok_Presence36, NoOneLikesJack, porichoygupto, jhn714, Attikey, LastProtagonist, electrocuter666, guamo17, Sjelan, stewithclou, Infectedtoe32, NobleMoistHam, VERBERD, tjeters, VAOkie, dbwebbco, st_jimmy_02, 1989JY_Ked Subscribe to this podcast via: iHeartMedia Spotify iTunes Google Podcasts YouTube Channel Social media: Instagram Facebook Twitter TikTok Discord Interested in advertising or sponsoring our show? Contact us at mediasales@klassicstudios.com Produced by Klassic Studios using AutoGen Podcast technology (http://klassicstudios.com/autogen-podcasts/) Learn more about your ad choices. Visit megaphone.fm/adchoices

    Bem Estar
    Bem-Estar #340: Obesidade em crianças e adolescentes: consequências na saúde e orientação para pais e cuidadores

    Bem Estar

    Play Episode Listen Later Mar 4, 2026 34:41


    O Atlas Mundial da Obesidade divulgado hoje no dia Mundial da Obesidade revela números impactantes. Até 2040, 507 milhões de crianças em idade escolar no mundo vão viver com sobrepeso ou obesidade. No Brasil, segundo dados do Sisvan, sistema que monitora o estado nutricional e consumo alimentar da população, 33% das crianças e adolescentes estão com excesso de peso e 13% com obesidade. Um estudo da Unifesp, publicado no International Journal of Obesity, identificou sinais precoces de inflamação e disfunção no endotélio – camada que reveste os vasos sanguíneos – em crianças com sobrepeso e obesidade. Isso comprova o que outros estudos já sinalizam: a obesidade aumenta o risco de doenças como aterosclerose, infarto e acidente vascular cerebral já na infância. Para evitar um cenário caótico na saúde pública, os governos precisam urgentemente intensificar a prevenção e o tratamento para crianças e adolescentes. Mas também há aquilo que cada um pode fazer em sua casa, com a sua família. É sobre todas essas ações que conversamos hoje com a endocrinologista Maria Edna de Melo, chefe da Liga de Obesidade Infantil do Hospital das Clínicas, da Faculdade de Medicina da USP, coordenadora da Comissão de Advocay da ABESO, Associação Brasileira para o Estudo da Obesidade e Síndrome Metabólica, e diretora do departamento de obesidade da SBEM, a Sociedade Brasileira de Endocrinologia e Metabologia.

    The Integrative Health Podcast with Dr. Jen
    Why Seed Oils Are Driving Obesity and Metabolic Dysfunction

    The Integrative Health Podcast with Dr. Jen

    Play Episode Listen Later Mar 3, 2026 48:30


    Seed oils are not just a modern cooking swap — they represent a dramatic shift in how we fuel our bodies. In this episode, Dr. Jen sits down with Steven Rofrano, founder of Ancient Crunch, to explore how vegetable oils moved from industrial products to dietary staples and why that change may be contributing to oxidative stress, mitochondrial dysfunction, and insulin resistance. They discuss the historical roots of seed oil adoption, the metabolic consequences of unstable omega-6 fats, the importance of ancestral food preparation methods like nixtamalization, and practical ways to reduce seed oil exposure without feeling restricted or extreme.Steven Rofrano is an entrepreneur and founder of Ancient Crunch, the company behind MASA chips and Vandy potato chips. After reversing his own chronic health issues through diet and lifestyle changes, Steven began educating others about ancestral eating and seed oil avoidance. His work focuses on bringing traditionally prepared, tallow-fried snacks to market while challenging modern food industry practices and promoting ingredient transparency.Website: https://www.masachips.comInstagram:  https://www.instagram.com/reallytanmanTiktok:  https://www.tiktok.com/@reallytanmanX:  https://x.com/reallytanmanPODCAST: Thank you for listening please subscribe and share! Shop supplements: https://healthybydrjen.shop/CHECK OUT a list of my Favorite products here: https://www.healthybydrjen.com/drjenfavorites FOLLOW ME:Instagram: https://www.instagram.com/integrativedrmom/Facebook: https://www.facebook.com/integrativedrmomYouTube: https://www.youtube.com/@integrativedrmom FTC: Some links included in this description might be affiliate links. If you purchase a product through one of them, I will receive a commission (at no additional cost to you). I truly appreciate your support of my channel. Thank you for watching! Video is not sponsored. DISCLAIMER: This podcast does not contain any medical or health related diagnosis or treatment advice. Content provided on this podcast is for informational purposes only. For any medical or health related advice, please consult with a physician or other healthcare professionals. Further, information about specific products or treatments within this podcast are not to diagnose, treat, cure or prevent disease.

    Fitness mit M.A.R.K. — Dein Nackt Gut Aussehen Podcast übers Abnehmen, Muskelaufbau und Motivation
    Verbrennt Protein wirklich mehr Kalorien? Was 52 Studien sagen (#561)

    Fitness mit M.A.R.K. — Dein Nackt Gut Aussehen Podcast übers Abnehmen, Muskelaufbau und Motivation

    Play Episode Listen Later Mar 3, 2026 28:52


    Samstagnachmittag, Supermarkt. Überall prangt das Wort „Protein“. Auf dem Joghurt, dem Milchreis, sogar auf den Nudeln. Und dann dieser Gedanke: Wenn Protein wirklich den Stoffwechsel ankurbelt – ist das der ultimative Geheimtrick zum Abnehmen?Eine aktuelle Meta-Analyse hat 52 Studien mit über 1.200 Teilnehmern ausgewertet, um genau das herauszufinden. Die Ergebnisse sind überraschend – und für Deine Ernährungsstrategie Gold wert.In dieser Folge erfährst Du:Warum der thermische Effekt von Protein in der Praxis massiv überschätzt wird – und welche Zahlen wirklich dahintersteckenWas eine proteinreiche Ernährung langfristig in Deinem Körper verändert (und warum es nicht der Kalorienverbrauch ist)Warum mein Klient Thomas mit 200 Gramm Protein am Tag trotzdem zunahm – und was Du daraus lernen kannstDie Protein-Anker-Methode und 5 weitere Quick Wins für Deinen AlltagWann mehr Protein wirklich nötig ist – und wann es nichts bringtWenn Du eine einzige Sache aus dieser Folge mitnimmst, dann diese: Protein ist beim Abnehmen Dein bester Freund – aber aus einem gänzlich anderen Grund, als Du bisher dachtest. Und Du erfährst, welcher das ist.____________*WERBUNG: Infos zum Werbepartner dieser Folge und allen weiteren Werbepartnern findest Du hier.____________Erwähnte Ressourcen und mehr zum Thema:Folge 490: Darmprobleme: Liegt's am Eiweiß? — mit Dr. med. Elke MantwillFolge 543: Die Protein-Lüge: Warum offizielle Empfehlungen Dich schwach haltenKalorienrechner auf marathonfitness.deMarks Proteinpulver-EmpfehlungenLiteratur:Guarneiri LL, et al. (2024). Effects of Varying Protein Amounts and Types on Diet-Induced Thermogenesis: A Systematic Review and Meta-Analysis. Advances in Nutrition, 15(12), 100332.Morton RW, et al. (2018). A systematic review, meta-analysis and meta-regression of the effect of protein supplementation on resistance training-induced gains in muscle mass and strength in healthy adults. British Journal of Sports Medicine, 52(6), 376–384.Helms ER, et al. (2014). A systematic review of dietary protein during caloric restriction in resistance trained lean athletes: a case for higher intakes. International Journal of Sport Nutrition and Exercise Metabolism, 24(2), 127–138.Wycherley TP, et al. (2012). Effects of energy-restricted high-protein, low-fat compared with standard-protein, low-fat diets: a meta-analysis of randomized controlled trials. American Journal of Clinical Nutrition, 96(6), 1281–1298.Moon J, Koh G. (2020). Clinical Evidence and Mechanisms of High-Protein Diet-Induced Weight Loss. Journal of Obesity & Metabolic Syndrome, 29(3), 166–173.Pesta DH, Samuel VT. (2014). A high-protein diet for reducing body fat: mechanisms and possible caveats. Nutrition & Metabolism, 11(1), 53.Quatela A, et al. (2016). The Energy Content and Composition of Meals Consumed after an Overnight Fast and Their Effects on Diet Induced Thermogenesis: A Systematic Review, Meta-Analyses and Meta-Regressions. Nutrients, 8(11), 670.Westerterp KR. (2004). Diet induced thermogenesis. Nutrition & Metabolism, 1(1), 5.Layman DK, et al. (2009). A moderate-protein diet produces sustained weight loss and long-term changes in body composition and blood lipids in obese adults. Journal of Nutrition, 139(3), 514–521.____________Shownotes und Übersicht aller Folgen.Trag Dich in Marks Dranbleiber Newsletter ein.Entdecke Marks Bücher.Folge Mark auf Instagram, Facebook, Strava, LinkedIn. Hosted on Acast. See acast.com/privacy for more information.

    Ones Ready
    Ep 561: Iran Airstrikes, Welfare Gluttony, and Fat Privilege

    Ones Ready

    Play Episode Listen Later Mar 2, 2026 41:32


    Send a textThis episode goes from CPR saves to cruise missiles real quick.Trent and Peaches kick it off with a legit shoutout to an EOD Airman who stepped up and saved a life off base. Then it pivots hard into Iran airstrikes, Middle East escalation, and whether “no new wars” actually means anything when presidents launch limited strikes. They talk Patriot batteries, decapitation strikes, Ukraine as a proving ground, and why geopolitics is never as simple as Twitter wants it to be.Then it turns into a full-blown rant.Obesity privilege tiers. SNAP averages. Government dependency. American culture being built on work. If you're looking for soft takes, this isn't it. They don't sugarcoat it, and they definitely don't apologize for believing discipline matters.It wraps with a serious question from a candidate about toxic teammates in the pipeline—and how to handle freeloaders without becoming one yourself.Geopolitics, personal responsibility, and team accountability. Welcome to the team room.⏱️ Timestamps: 00:00 EOD Airman saves a life with CPR 06:00 Iran strikes, Patriot defenses, and escalation 12:00 No new wars or just limited military ops? 18:00 Ukraine as a proving ground 25:00 Obesity “privilege” tiers meltdown 29:00 SNAP averages and the welfare rant 33:00 Dependency vs American work culture 39:00 Handling bad teammates in the pipeline 45:00 Insulate or isolate? Team accountability

    HAYVN Hubcast
    Beyond the GLP-1 Boom: Building Sustainable Cardiometabolic Care EP 135

    HAYVN Hubcast

    Play Episode Listen Later Mar 2, 2026 24:51


    In this episode of the HAYVN Hubcast, Nancy Sheed welcomes back Katherine Saunders, co-founder of FlyteHealth, for a powerful conversation on the evolution of obesity and cardiometabolic care. Since her last appearance—when her company was still in its early stages under the name IntelliHealth—Katherine has led a transformation from a software-focused startup into a comprehensive virtual clinical care provider. Now rebranded as FlyteHealth, the company delivers integrated cardio-kidney-metabolic care directly to patients, while partnering with employers to reduce healthcare costs and improve outcomes. Katherine explains how the rise of GLP-1 medications like Wegovy, Ozempic, and Zepbound changed the national conversation around obesity. But she cautions against the current “GLP-1-only” mindset, emphasizing that true success requires comprehensive medical evaluation, personalized treatment plans, and ongoing support—not just a prescription. The discussion explores: Why obesity medicine was historically overlooked in medical training How GLP-1 demand has reshaped employer healthcare strategies The financial strain these medications place on self-insured employers Why fragmented healthcare leaves patients overwhelmed The importance of care navigation and communication between specialists How technology can enhance—not replace—the provider-patient relationship FlyteHealth's model blends advanced clinical decision support tools with human-centered care, allowing providers to practice at the top of their training while delivering better outcomes for patients and better ROI for employers. Key Highlights From Software to Full-Service Clinical CareFlyteHealth began as a tech platform to scale obesity treatment but evolved into a direct care provider when it became clear that technology alone wasn't enough. The GLP-1 Explosion — and Its LimitsWhile GLP-1 medications have revolutionized obesity treatment, Katherine stresses that medication without comprehensive care leads to poor outcomes and rising costs. The Employer Healthcare DilemmaSelf-insured employers face skyrocketing costs for GLP-1 medications. FlyteHealth offers a structured, outcomes-focused program that balances access with cost control. Obesity as a Root DiseaseTreating obesity improves or prevents over 200 related conditions, including hypertension, prediabetes, and cholesterol issues—making integrated care essential. Technology as a Support System, Not a SubstituteClinical decision support tools gather and analyze data before visits, allowing providers to spend more time educating and connecting with patients. This conversation highlights a pivotal moment in healthcare. The excitement around GLP-1 medications has brought long-overdue attention to obesity as a serious medical condition—but as Katherine makes clear, prescriptions alone are not the solution. Sustainable results require comprehensive care, personalized treatment, coordinated communication, and smart use of technology. FlyteHealth represents a model for where healthcare is heading: integrated, data-informed, and human-centered. As employer-sponsored healthcare continues to evolve and new therapies enter the market, thoughtful systems like this may be what keeps care both effective and financially sustainable. Connect with Nancy LinkedIn  Instagram Website Connect with Katherine LinkedIn Website Learn more about your ad choices. Visit megaphone.fm/adchoices

    Wake Up, Look Up
    Should the Government Fund Obesity?

    Wake Up, Look Up

    Play Episode Listen Later Mar 2, 2026 5:52


    In this episode of Wake Up, Look Up, Pastor Zach tackles the debate over whether government food assistance programs should restrict the purchase of junk food, exploring what true compassion and responsible provision really look like. Drawing on recent statistics and a biblical framework, he argues that helping people thrive means using wisdom–not enabling harmful choices that lead to long-term consequences. Through practical examples and Scripture, Pastor Zach challenges listeners to think critically about generosity, accountability, and what it means to care for others in a way that reflects the heart of Christ.Have an article you'd like Pastor Zach to discuss? Email us at wakeup@ccchapel.com!

    CME in Minutes: Education in Primary Care
    Managing Obesity as a Chronic Condition: The Role of Incretin-Based Therapies in Personalized Care

    CME in Minutes: Education in Primary Care

    Play Episode Listen Later Mar 2, 2026 61:01


    Please visit answersincme.com/860/240201356-replay to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Sue D. Pedersen, MD, FRCPC, DABOM; Leon Waye, MD; and Basel Bari, MD, MCFP. In this activity, experts in obesity discuss treatment management with a focus on the role of incretin-based therapies. Upon completion of this activity, participants should be better able to: Explain the rationale for managing obesity as a chronic, treatable disease; Discuss the latest evidence for incretin-based therapies in the management of obesity, including clinical outcomes and safety profiles; and Identify patients who might benefit from incretin-based therapies as part of a comprehensive treatment plan for obesity.

    Everyday Wellness
    Ep. 561 Why Eating Less Isn't Working – The Real Root Causes of Obesity & Metabolic Disease with Dr. Jason Fung | Menopause & Metabolic Health

    Everyday Wellness

    Play Episode Listen Later Feb 28, 2026 66:12


    I am delighted to reconnect with Dr. Jason Fung today. He is a trained nephrologist and world-leading expert on intermittent fasting and metabolic health. He has authored multiple books, including the New York Times best-seller, The Obesity Code, The Diabetes Code, and, more recently, The Hunger Code.   In our conversation today, we unpack the obsessive focus on the calories-in, calories-out model, which is neither practical nor effective. We explore the root causes behind the narrow-minded thinking that calories alone drive obesity, differences between types of hunger and conditioned responses, how hormones affect other hormones, and lessons about GLP-1s. We examine the critical importance of fiber and protein, and offer clarity around carbohydrates. We also cover the impact of meal timing, sleep, and circadian biology, the fat thermostat and sympathetic tone, nutrition, stress, and mindful eating, and dive into the issue of ultra-processed foods. Join us for an insightful conversation that challenges conventional wisdom and offers a nuanced and sustainable approach to understanding hunger, metabolism, and long-term health. IN THIS EPISODE, YOU WILL LEARN: “Calories in, calories out” framework is technically correct, but practically useless How the homeostatic, hedonic, and conditioned hunger types differ Dr. Fung shares his take on GLP-1 medications How fiber stimulates natural GLP-1 production Processed and natural carbohydrates produce vastly different glucose and insulin responses. Avoid eating late-night meals! Complex relationship between hunger, hormonal regulation, and sleep quality Hormones that drive body fat regulation  How bitter foods suppress appetite and enhance satiety Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow  Cynthia's Menopause Gut Book is on presale now! Cynthia's Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Connect with Dr. Jason Fung On his website Instagram and YouTube Dr. Fung's latest book, The Hunger Code, will come out in March. Pre-order on Amazon!

    The People's Pharmacy
    Show 1463: Why We Eat Too Much and What to Do About It

    The People's Pharmacy

    Play Episode Listen Later Feb 27, 2026 58:21


    Obesity is a big problem in the US. The National Institute of Diabetes and Digestive and Kidney Diseases says 2 out of every 5 American adults are obese. What's more, one in three is overweight, with only about 25 percent of us at a healthy weight. It's not just adults; children are increasingly suffering weight […]

    The Breast Cancer Recovery Coach
    #452 Fats And Breast Cancer - Breast Cancer and Nutrition, Just The Facts

    The Breast Cancer Recovery Coach

    Play Episode Listen Later Feb 27, 2026 24:09


    In this week's podcast episode in the Nutrition After Breast Cancer: Just the Facts series, I bring up the study that sparked that concern. I don't ignore things like this. I don't pretend they don't exist. If there's research being talked about, I want you to know about it. But here are the actual facts. The study was done in mice. The mice were made to consume about 40% of their diet in olive oil. And the rest of their diet was an obesogenic, high-carbohydrate diet designed to promote weight gain and metabolic dysfunction. That is not a Mediterranean diet. That is not olive oil drizzled over vegetables and salmon. That is not real life. It was a laboratory model designed to stress metabolism. Context matters. Deeply.   Resources Mentioned: Guide to Essential Fatty Acids: https://www.thebreastcancerrecoverycoach.com/oil Episode #326 Simplifying Seed Oils and Fatty Acids After Breast Cancer https://www.thebreastcancerrecoverycoach.com/326   Work with Laura: https://www.thebreastcancerrecoverycoach.com/health      REFERENCES: Obesity and Low-Fat Diet History Trends in Obesity Among Adults in the United States, 2005 to 2014 (CDC) https://www.cdc.gov/mmwr/preview/mmwrhtml/su6001a15.htm Documents obesity prevalence: 15.0% (1976-1980), 23.3% (1988-1994) Adult Obesity Prevalence Maps (CDC) https://pmc.ncbi.nlm.nih.gov/articles/PMC9611578/ 30.9% obesity prevalence (1999-2000) Adult Obesity Prevalence, 2021-2023 (CDC) https://www.cdc.gov/nchs/products/databriefs/db508.htm Current obesity prevalence: 40.3% How the Ideology of Low Fat Conquered America https://pubmed.ncbi.nlm.nih.gov/18296750/ Historical analysis of the low-fat movement Heart Disease Mortality Explaining the Decrease in U.S. Deaths from Coronary Disease, 1980–2000 (Ford et al., NEJM 2007) https://www.nejm.org/doi/full/10.1056/NEJMsa053935 ~51% decline in men, ~49% decline in women 47% from medical treatments, 44% from risk factor changes Obesity and diabetes offset gains by 8% and 10% Heart Disease Mortality in the United States, 1970 to 2022 https://www.ahajournals.org/doi/10.1161/JAHA.124.038644 89% decrease in heart attack deaths 81% increase in heart failure and other heart disease deaths Omega-3s, Inflammation, and Cancer Omega-6/Omega-3 Ratios and Modern Diets Ancestral ratios: 1:1 to 4:1 Modern Western diet: 15:1 to 20:1 Impact on eicosanoid metabolism and cellular inflammation DHA and Triple Negative Breast Cancer (Journal of Nutritional Biochemistry, 2019) DHA induced cell death in TNBC cells Mechanism: altered membrane composition, increased oxidative stress in cancer cells High-Fat Diets and TNBC Metastasis (Preclinical Studies) CD36-mediated fatty acid uptake in TNBC Oleic acid-rich diets promoting metastasis in mouse models Importance of tumor phenotype and metabolic flexibility   Let's Connect! If this episode helped you breathe a little easier, please share it with a friend or leave a review. Every share helps spread this message of hope, healing, and whole-person wellness.

    MedEvidence! Truth Behind the Data
    The Triangle Method for Metabolic Syndrome

    MedEvidence! Truth Behind the Data

    Play Episode Listen Later Feb 25, 2026 18:13 Transcription Available


    Send a textDr. Gagandeep Singh joins Dr. Michael Koren to discuss his triangle approach, which combines the talents of a medical doctor, a nutritionist, and a trainer to tackle the medications, diets, and exercise changes needed to make a difference in metabolic diseases. Metabolic diseases include diabetes, hypertension, obesity, and polycystic ovary syndrome (PCOS). Dr. Singh, who practices in India, explains how this holistic approach has resulted in high success rates, with patients improving their lab numbers, losing weight, and reducing their medications as he "treats to success."Be a part of advancing science by participating in clinical research.Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.comListen on SpotifyListen on Apple PodcastsWatch on YouTubeShare with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released.Follow us on Social Media:FacebookInstagramX (Formerly Twitter)LinkedInWant to learn more? Checkout our entire library of podcasts, videos, articles and presentations at www.MedEvidence.comMusic: Storyblocks - Corporate InspiredThank you for listening!

    The Energy Balance Podcast
    BV #24: Nick Norwitz Says Calories Don't Cause Obesity. Is He Wrong?

    The Energy Balance Podcast

    Play Episode Listen Later Feb 24, 2026 52:44


    In this episode we discuss: 
-The calories in calories out model of obesity  -What really causes fat storage  -Whether there are any concerns with consuming organ meats    
Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide 
The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/ 
Theresa's Instagram: https://www.instagram.com/livingrootswellness/   
Timestamps: 0:00 – intro  0:56 – Nick Norwitz's claim that calories don't cause obesity and whether we agree  6:25 – the value and limitations of calories   14:27 – the true cause of obesity  19:40 – “excess calorie intake causes weight gain” is unhelpful and irresponsible  23:28 – how and when measuring calorie intake can be valuable  27:24 – do calories matter?  32:28 – how “it's just calories” often places blame on the individual  34:26 – Nick Norwitz on when the calories-in-calories-out model “breaks”  37:28 – hypothyroidism and weight gain resolved using a bioenergetic approach  38:26 – thoughts on organ meats like liver, heart, kidney, stomach, and intestine  42:41 – freeze-dried or desiccated vs fresh organ meat  45:12 – Nutrition with Judy's claim that “liver is not a superfood”  47:11 – can you overdose micronutrients like vitamin A and copper from organ meats?  49:43 – strategies for including more organ meats in your diet

    Science Weekly
    The truth about fat, and its complex role in our health

    Science Weekly

    Play Episode Listen Later Feb 24, 2026 16:32


    For a long time fat was seen simply as an inert yellow substance wrapping around our bodies, but now that's changing. Scientists are beginning to understand that our fat is actually intricate and dynamic, constantly in conversation with the rest of the body. It's now even considered by some to be an organ in its own right. To find out more about the complex role fat plays in our health, Ian Sample hears from co-host Madeleine Finlay and from Declan O'Regan, professor of cardiovascular AI at Imperial College London. Help support our independent journalism at theguardian.com/sciencepod

    Inside Health
    What are the side effects of weight loss drugs?

    Inside Health

    Play Episode Listen Later Feb 24, 2026 28:03


    Over 1.5million adults in the UK tried weight loss drugs in 2024-25. Many swear by them, but they have been associated with side effects including nausea and, in some cases, extremely painful gallstones. But what does the evidence actually tell us, and what is the wider impact on the way we view our bodies in society?James Gallagher is joined by Professor of Cardiometabolic Medicine at the University of Glasgow Naveed Sattar, Dr Beverley O'Hara, Lecturer in Public Health Nutrition at Leeds Beckett University, and Dr Margaret McCartney, resident Inside Health GP. They discuss what the evidence tells us about the potential known side effects of these weight loss drugs, and the potential impact their use has on our view of obesity as a society. We also hear from Sarah Le Brocq, who has struggled with obesity all her adult life and has been on these drugs for the past 2-3 years about her experiences. Margaret McCartney has no conflicts of interest to declare.Beverley O'Hara has no conflicts of interest to declare. She has 2 roles with the Association for the Study of Obesity (voluntary academic positions).Naveed Sattar has consulted for and/or received speaker honoraria from AbbVie, Amgen, AstraZeneca, Boehringer Ingelheim, Carmot Therapeutics, Eli Lilly, Gan & Lee, GlaxoSmithKline, Hanmi Pharmaceuticals, Kailera, Mass Medicines, Menarini-Ricerche, Metsera, Novo Nordisk, Pfizer, Regeneron, Roche, UCB Pharma, and Verdiva Bio; and received grant support paid to his University from AstraZeneca, Boehringer Ingelheim, Novartis, and Roche.Presenter: James Gallagher Producer: Hannah Fisher Researcher: Tom Hunt Production coordinator: Stuart Laws Content Editor: Ilan Goodman

    Mind & Matter
    Circadian Rhythms, Metabolism & Why Timing Your Meals Matters | Dr. Joseph Bass

    Mind & Matter

    Play Episode Listen Later Feb 23, 2026 91:03


    Send a textHow the body's internal circadian clocks regulate metabolism, energy balance, and health.TOPICS DISCUSSED:Master circadian clock in the brain: Light detection via retina entrains the suprachiasmatic nucleus, which coordinates body-wide rhythms; intrinsic period slightly deviates from 24 hours, allowing seasonal flexibility.Peripheral clocks in organs: Nearly all cells have autonomous clocks; liver and fat clocks rapidly adjust to feeding time, while brain clock aligns more tightly to light.Clock mutations and metabolism: Disrupting core clock genes (e.g., CLOCK, BMAL1) causes obesity, liver fat accumulation, and impaired insulin secretion without hyperinsulinemia.Timing of food intake: Eating the same high-fat calories during rest phase causes more weight gain than during active phase due to differences in energy dissipation.Modern disruptions (jet lag, shift work, blue light): Create desynchrony between brain and peripheral clocks, contributing to metabolic issues; late-night eating impairs glucose handling.Critical illness & feeding: Tube feeding at night (opposite natural cycle) induces rapid insulin resistance, highlighting mismatch costs.Hormone rhythms: Testosterone, glucocorticoids, and others peak at specific times; misalignment affects stress, reproduction, and metabolism.Weight loss drugs & maintenance: GLP-1 drugs reduce intake effectively, but regain involves neuroendocrine adaptations tied to brain clock pathways.ABOUT THE GUEST: Joseph Bass, MD, PhD is Chief of Endocrinology, Metabolism and Molecular Medicine at Northwestern University Feinberg School of Medicine, Director of the Center for Diabetes and Metabolism, and a leading researcher who pioneered the link between circadian clock genes and metabolic disorders including obesity and diabetes.RELATED EPISODE:M&M 237 | Circadian Biology: Genetics, Behavior, Metabolism, Light, Oxygen & Melatonin | Joseph TakahashiSupport the showHealth Products by M&M Partners: SporesMD: Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off. Lumen device: Optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off. AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models. Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) For all the ways you can support my efforts

    The School of Doza Podcast
    How To Lose Weight Without Ozempic

    The School of Doza Podcast

    Play Episode Listen Later Feb 23, 2026 31:11


    Discover how to lose weight without Ozempic using 5 evidence-backed strategies. This episode breaks down why insulin resistance is the real driver of weight gain and how cutting processed foods, eating only when hungry, fasting, weight resistance training, and detoxification can help you lose weight naturally and sustain it long-term — no prescription required. FEATURED PRODUCT The Good Poops Protocol is designed to support the exact systems discussed in this episode — liver detoxification, gut health, and blood sugar regulation. 

    Fast Keto with Ketogenic Girl
    Protein Fasting: The Upgrade to Intermittent Fasting for Sustainable Fat Loss

    Fast Keto with Ketogenic Girl

    Play Episode Listen Later Feb 20, 2026 54:37


    Is fasting really the best way to lose fat — or is there a smarter, more strategic approach? In this masterclass episode, Vanessa introduces a powerful new concept: Protein Fasting — a structured approach using PSMF (Protein-Sparing Modified Fast) days to optimize fat loss, suppress appetite naturally, protect muscle, and potentially tap into fasting-like cellular signaling.

    The Jordan Syatt Mini-Podcast
    The Top 3 Glute Exercises, Beginners Guide to Running, Muscle Growth Science, Oprah's Obesity Gene, and More...

    The Jordan Syatt Mini-Podcast

    Play Episode Listen Later Feb 18, 2026 150:59


    In this episode of The Jordan Syatt Podcast I speak with Jordan Lips (@jordanlipsfitness) and we discuss:- The top 3 glute exercises- The best sources of fiber- Surprisingly high quality protein sources- How heavy do you need to lift for strength and muscle?- Beginners guide to running- Oprah's "obesity gene"- The seed oil debate- The governments new nutrition guidelines- And more...I hope you enjoy this episode and, if you do, please leave a review on iTunes (huge thank you to everyone who has written one so far).Finally, if you've been thinking about joining The Inner Circle but haven't yet... we have hundreds of home and bodyweight workouts for you and you can get them all: https://www.sfinnercircle.com/

    The Michael Berry Show
    PM Show Hr 1 | MAHA is Addressing Obesity as the Health Problem It Is

    The Michael Berry Show

    Play Episode Listen Later Feb 12, 2026 34:01 Transcription Available


    See omnystudio.com/listener for privacy information.

    Dr. Joseph Mercola - Take Control of Your Health
    The Hidden Reason Vitamin D Fails in People with Obesity

    Dr. Joseph Mercola - Take Control of Your Health

    Play Episode Listen Later Feb 12, 2026 5:01


    Extra body fat interferes with how vitamin D works after it enters your body, which explains why low levels often persist despite supplements or sun exposure Vitamin D can become trapped in fat tissue and fail to convert into its usable form, leaving blood tests low even when intake appears sufficient Deep belly fat and liver fat have the strongest impact on vitamin D availability, making waist size more important than body weight alone Taking higher doses of vitamin D doesn't always fix the problem if metabolic signals from excess fat remain unchanged Reducing visceral fat, restoring metabolic health, and supporting proper vitamin D activation help vitamin D function normally again