Podcasts about medical research institute

Paul Dorin is a station commander with Fire and Rescue NSW and in 2024 received the Australian Fire Service Medal in the King's Birthday Honours for more than 30 years of service as a senior NSW firefighter. Based at Corrimal Fire Station in NSW Paul has a passion for helping others and has become a role model for his peers and local community which has seen Paul develop many safety initiatives. Firstly, the Home Care Disability Fire Safety Program in which he promoted fire safety efforts involving clients and their carers, and secondly the winter's Smoke Alarm Action Day project, known as SAAD which takes place on June 1st every year. When not at the Fire Station, Paul is an incredible cartoonist, and we are proud to say he is the Illustrator behind all of our books which bring the stories to life in a spectacular way. Paul began drawing cartoons when he was very young at school, but before drawing l had a passion for modelling things out of plasticine. His late brother Steven was his inspiration to swap the plasticine to pen and ink and the family Louvre kitchen gallery eventually led to Paul getting his first published cartoon in The Bulletin magazine back in 1984. Today his cartoons appear in suburban & regional newspapers all around Australia and different parts of the world, and of course in our books, for which we could not be more grateful. Over the years Paul has supported the Jean 4 genes charity raising money for the Children's Medical Research Institute by painting on the jeans of celebrities such as Mike Tyson, actors Robin Williams, Jonah Hill, Jim Belushi, Keven Kline, Frances Mc Dormand, David Hasselhoff to name but a few.

A recent scroll of your social media feed might have made you feel like you were back in 2020. Footage of overwhelmed hospital emergency rooms in China have been doing the rounds online, with claims that a new and mysterious virus is sweeping the country and making people unwell. So, can we trust these reports? What is actually causing people to get sick in China right now? And are we at risk of it in Australia? On this episode of The Briefing, Sacha Barbour Gatt is joined by Professor Jill Carr from Flinders Health and Medical Research Institute to breaks down HMPV, it’s severity and whether we’re at risk here in Australia. Follow The Briefing: TikTok: @listnrnewsroom Instagram: @listnrnewsroom @thebriefingpodcast YouTube: @LiSTNRnewsroom Facebook: @LiSTNR NewsroomSee omnystudio.com/listener for privacy information.

The MRI technique advances coming out of the Mātai Medical Research Institute in Gisborne have been described as ‘pioneering', ‘groundbreaking' and ‘world leading'. Claire Concannon speaks to chief executive and research director Dr Samantha Holdsworth to learn why, and about their big plans for the future.

The MRI technique advances coming out of the Mātai Medical Research Institute in Gisborne have been described as ‘pioneering', ‘groundbreaking' and ‘world leading'. Claire Concannon speaks to chief executive and research director Dr Samantha Holdsworth to learn why, and about their big plans for the future.  

 Penny Lamont from the Wagga CMRI Committee joined Jamie & Leigh to run them through this year's fair, and also talk about the amazing work of the Children's Medical Research Institute.See omnystudio.com/listener for privacy information.

Primary results from ASC4FIRST trial, the first study in chronic myeloid leukemia comparing current standard-of-care frontline tyrosine kinase inhibitors with the novel agent asciminib in newly diagnosed patients, were reported at the 2024 ASCO Annual Meeting. First author Timothy Hughes MD, Consultant Hematologist with the Royal Adelaide Hospital, the South Australian Health and Medical Research Institute, and the University of Adelaide in Australia, reported higher efficacy in terms of major molecular responses and lower toxicity with asciminib. After his talk in Chicago, he met up with Oncology Times reporter, Peter Goodwin.

New Zealand is leading the world in asthma management due to the nationwide uptake of a 2-in-1 inhaler regime. Historically asthma has been treated by prescribing separate reliever and preventer inhalers, but the results of a recent study released by the Medical Research Institute of New Zealand show the combination 2-in-1 inhaler has significantly reduced the number of asthma related hospital admissions in Aotearoa over the last four years. Professor Richard Beasley is the Director of the Medical Research Institute of New Zealand and is also the asthma programme lead.

A new study has found machine learning can significantly improve patient outcomes in the ICU. Wellington intensive care specialist, Professor Paul Young, also Deputy Director of the Medical Research Institute explains.

There are many Cochrane Pregnancy and Childbirth reviews of interventions to prevent health problems in babies that are born early. One of these was updated in April 2024, looking at the evidence on the effects of receiving magnesium sulphate prior to early birth. Lead author, Emily Shepherd from the South Australian Health and Medical Research Institute and University of Adelaide in Australia tells us about the latest findings in this podcast, with a focus on the prevention of cerebral palsy.

There are many Cochrane Pregnancy and Childbirth reviews of interventions to prevent health problems in babies that are born early. One of these was updated in April 2024, looking at the evidence on the effects of receiving magnesium sulphate prior to early birth. Lead author, Emily Shepherd from the South Australian Health and Medical Research Institute and University of Adelaide in Australia tells us about the latest findings in this podcast, with a focus on the prevention of cerebral palsy.

The fight against the spread of Tuberculosis (TB) has been thrust back into the spotlight following a march by more than 600 Gauteng-based TB activists affiliated with the NPO, Rural Health Advocacy Project. The group has called for better co-ordination and greater political priority if government aims to eradicate TB by the year 2030. The march comes a just days after the Bill & Melinda Gates Medical Research Institute launched Phase 3 of a clinical trial to assess the efficacy of a TB vaccine which could potentially help prevent pulmonary TB in adolescents and adults. Sakina Kamwendo spoke to national principal investigator for the experimental vaccine called M72/AS01E (M72 for short)in South Africa, Dr Lee Fairlie.

In this ToxChats© episode, we interview Dr. Chris Christou, Director of Preclinical Imaging and Research Laboratories at the South Australian Health and Medical Research Institute. Dr. Christou discusses the history of sheep as a preclinical species for medical device testing, novel groundbreaking neurological disease models, and the use of sheep as an alternative model in general toxicology studies. Critical regulatory standards and international guidelines are discussed to ensure successful submissions with the US Food and Drug Administration, the Australia Therapeutic Goods Administration, and the Australia New Zealand Therapeutic Products Agency.

In the conclusion to our engaging interview with Dr. Claire Wagner, Head of Corporate Strategy & Market Access at the Bill & Melinda Gates Medical Research Institute, hosts Sophie Neale and Dr. Tanner Schrank discuss her journey through medical school, the impact that working with the WHO had on her, and how mentors shaped her life. Tune in to find out her insightful advice on following your own path, keeping an open mind, and finding passion in your work! Bill & Melinda Gates Medical Research Institute: https://www.gatesmri.org/leadership/claire-m-wagner/Dr. Claire M. Wagner: https://www.linkedin.com/in/clairemwagner/ Sign up for a free 5-day trial at https://go.amboss.com/pod-5day-trial. Read more at the AMBOSS blog: https://go.amboss.com/blog-ambosspod. Find out more about the AMBOSS podcast: https://go.amboss.com/int_podcast-23.

As we continue our exciting mini-series of Leading Women in Healthcare, hosts Sophie Neale and Dr. Tanner Schrank dive into the important theme of Global Health with Dr. Claire M. Wagner, a leading figure in the sphere and current Head of Corporate Strategy & Market Access at the Bill & Melinda Gates Medical Research Institute. This episode (part 1 of 2) focuses on Claire's extensive experience, highlighting her incredible journey ensuring care and access around the world, and pinpointing the most crucial challenges in global health today. Join us as we go beyond the textbook! Bill & Melinda Gates Medical Research Institute: https://www.gatesmri.org/leadership/claire-m-wagner/Dr. Claire M. Wagner: https://www.linkedin.com/in/clairemwagner/ Sign up for a free 5-day trial at https://go.amboss.com/pod-5day-trial. Read more at the AMBOSS blog: https://go.amboss.com/blog-ambosspod. Find out more about the AMBOSS podcast: https://go.amboss.com/int_podcast-23.

#S4:E6 — Karen Hogg is a Technical Specialist at the University of York, and Margaret Mbuchi is a Principal Research Scientist at the Kenya Medical Research Institute. In this episode of Flow Stars, Karen and Margaret join Peter O'Toole to celebrate the achievements of flow cytometry initiatives across Africa and discuss some of the logistical challenges involved. Karen shares some of the logistical and technical hurdles involved in transporting cytometers and reagents to African countries, and Margaret shares some of the issues that can arise when recruiting study participants in areas of civil unrest. If you want to get involved and support research in resource-poor areas, find out how to donate spare instruments via the International Society for the Advancement of Cytometry Instruments 4 Science program. Visit the ISAC website to donate online. Watch or listen to all episodes of Flow Stars: flowstars.bitesizebio.com

On today's podcast, Ric examines an advancement from the Medical Research Institute at Kitano Hospital in Japan, where scientists are preparing to test a drug that could enable the regrowth of teeth. With clinical trials set to begin next year, this innovation could transform dental care by providing an alternative to dentures and implants. This innovation could benefit individuals with genetic conditions like anodontia, along with tooth loss from cavities or other aliments. The promise of regenerating teeth could become a reality for patients within this decade.Subscribe to podcast updates: https://form.jotform.com/223614751580152Ask Ric: https://www.thetayf.com/pages/ask-ricRic's Books: https://www.amazon.com/stores/Ric-Edelman/author/B000APYJPM-----Links from today's show:Self-care with Jean Edelman: https://selfcarewithjean.com/-----Follow Ric on social media:Facebook: https://www.facebook.com/RicEdelmanInstagram: https://www.instagram.com/ric_edelman/ LinkedIn: https://www.linkedin.com/in/ricedelman/X (formerly Twitter): https://twitter.com/ricedelman YouTube: https://www.youtube.com/@RicEdelman-----Brought to you by:Global X ETFs: https://www.globalxetfs.com/Invesco QQQ: https://www.invesco.com/qqq-etf/en/home.htmlSchwab: https://www.schwab.com/Disclosure page: https://www.thetayf.com/pages/sponsorship-disclosure-fee-----

John MacKenzie chats with Associate Professor Severine Navarro, Team Head of Mucosal Immunology at QIMR Berghofer Medical Research Institute, about groundbreaking trials of a new treatment for asthma sufferers. The QIMR Berghofer Institute is appealing for donations to help fast-track clinical trials for a new anti-inflammatory protein that can now be synthesised. The protein is proving effective to treat asthma and could potentially work to treat a range of other conditions including hay fever, food allergies, and even coeliac. 

Professor Mike Berridge completed a doctoral degree in cell biology at the University of Auckland in 1971 exploring the mechanism of action of plant growth hormones. Following postdoctoral research in developmental molecular biology at Purdue University, USA, and experience as a staff scientist at National Institute for Medical Research, Mill Hill, UK, he returned to Wellington in 1976 as the second Malaghan Research Fellow where he established the Cancer Cell & Molecular Biology Research Group and was a founding scientist of the Wellington Cancer & Medical Research Institute, later renamed the Malaghan Institute of Medical Research in recognition of major personal support by Len and Anne Malaghan.Prof Berridge received a James Cook Fellowship in the health sciences in 2003 and was awarded the Health Research Council Liley Medal for outstanding research on cellular metabolism in 2016. In the same year he was a semi-finalist in the KiwiBank New Zealander of the Year Awards.Prof Berridge's current research interests include cancer cell energy metabolism and mitochondrial gene transfer between cells in human disease. As a science communicator, he recently published “The Edge of Life” (2015), and “Sugar, Rum and Tobacco: Taxes and Public Health in New Zealand” with Lisa Marriott in 2017. In 2023 Mike received a Doctor of Science from Victoria University of Wellington for his lifetime achievements in science.https://www.wgtn.ac.nz/news/2022/09/professor-michael-berridgehttps://www.malaghan.org.nz/our-expertise/our-people/science-leadership/professor-mike-berridge/https://www.malaghan.org.nz/news-and-reports/news/professor-mike-berridge-a-journey-through-the-frontiers-of-the-biological-sciences/

Ready to discover the hidden wisdom of "just keep turning up"? Check out this episode with guest Andrew Kelly on the power of curiosity and unstoppable motivation! This inspiring journey is guaranteed to help you move forward one step at a time.Here's some of the great stuff that we cover in this show:Andrew became interested in cycling in his early teenage years. He went on to pursue this passion and raced competitively in Australia and Europe, but had to stop due to a burst appendix, which almost killed him. but looking back, he feels happy about how things turned out.He shares how the lessons learned from road cycling - such as the importance of conserving energy and always showing up - have impacted his life.He credits his coach with teaching him the "great secret" of just turning up, which has led to success both in his career and personal relationships.He attributes his success to curiosity, something that drives him to constantly seek out new information and knowledge.Andrew is an avid reader and considers reading a valuable pastime because it requires imagination and effort. It also helps spark new ideas and fuel curiosity.Talking about his work with the Antarctic Science Foundation, Andrew shares how Antarctica is a huge repository of information that could help us understand our moment in time and build strategies to mitigate climate change.----------------------ABOUT ANDREWAndrew Kelly started his career with eight years in banking and at the same time, competed at an elite level in Road Cycling. It was here that Andrew learned the importance of preparation for racing, training, visualisation, strategy, analysis, persistence, tenacity, determination, accountability…and, as we are talking about today - the unsexy wisdom behind the idea of just keep turning up.He went on to build and sell an advertising agency before heading to the third sector captivated with the idea of doing good in society. Across two decades, he has witnessed the power of generosity by facilitating transformational gifts to Youth Off The Streets, The Smith Family, The Refugee Advice and Casework Service (RACS), the Society of St Vincent De Paul and Children's Medical Research Institute.Andrew is now the CEO of The Antarctic Science Foundation, which creates connections between philanthropists and researchers to enable catalytic scientific research on the Icy Continent and is an Observer on the Australian Antarctic Science Council.He still cycles around 300km per week, plays the piano and guitar, reads lots of books but his self-proclaimed favourite role is simply being a dad!----------------------For complete show notes, transcript and links to our guest, check out our website: www.pushtobemore.com.

John MacKenzie chats with Associate Professor Michelle Wykes, Group Leader of Molecular Immunology at QIMR Berghofer Medical Research Institute, about breakthrough cancer research in regard to both breast and bowel cancer. The discovery of a so-called "master switch" is being understood in efforts to potentially turn on vital dendritic cells, which act like the generals of the immune system, to fight particular tumours. "We're seeing palpable tumours that completely disappear and melt away," Michelle Wykes said.

In this special episode, we focus on the power of mentoring to develop and empower women throughout the world. We will hear from Dr. Damaris Matoke-Muhia, who is an entomologist and a leader in the fight against malaria and other vector control diseases. Dr. Matoke-Muhia is passionate about identifying and mitigating gaps women face culturally in implementing community-based solutions to reduce malaria and in going into vector control research. Her story illustrates how one woman's courage to challenge a system has positively impacted the lives of women and children throughout Africa.

Researchers find Cordyceps used in traditional medicine can fight cancer Shanghai Institutes for Biological Sciences, October 23, 2022 Chinese scientists have found evidence that a fungus used in traditional Chinese medicine widely sought by the public for its healing powers, also carries anti-cancer benefits. The scientists found there was an interaction between two anti-cancer compounds in the fungus Cordyceps militaris. The first, cordycepin, was noted in Cordyceps militaris in 1950, but how it interacted remained unknown. The second, pentostatin, was first identified from a bacterium and was developed as a commercial drug to treat leukemia and other cancers in the 1990s. “For the first time, we decoded the biosynthesis mechanism of cordycepin in the fungus, and during the research we unexpectedly discovered pentostatin,” said Wang Chengshu, head of the research team at the Institute of Plant Physiology and Ecology, a branch of the Shanghai Institutes for Biological Sciences of the Chinese Academy of Sciences. “These two compounds coexist in fungal cells in the form of a protector and protege – that is to say, cordycepin is synthesized with the coupled production of pentostatin to protect the stability of the former,” he said. Their research also showed that the fungus initiates a detoxification process when the cordycepin in the body reaches an excessively high level, which can be toxic. Cordyceps fungi are popular in China for their widely believed immunity-enhancing and energy-strengthening properties. Their uses in medical treatment date to the Compendium of Materia Medica, a book widely deemed the encyclopedia of traditional Chinese medicine written in the Ming Dynasty (1368-1644). Omega-3 fatty acid could boost IQ for preterm babies South Australian Health and Medical Research Institute, October 27, 2022 New research from SAHMRI has found a link between the omega-3 fatty acid known as docosahexaenoic acid (DHA) and increased IQ among children born prematurely. Preterm children are more likely to have lower IQ scores and cognitive impairments compared with term-born children. Dr. Jacqueline Gould, who led the study now published in the New England Journal of Medicine, says infants born at the earliest gestations are deprived of the natural supply of DHA that normally builds up in the brain during the last trimester of pregnancy. “These babies have low concentrations of DHA in their brain tissue, which may contribute to poorer cognitive outcomes,” Dr. Gould said. The study followed 323 infants born before 29 weeks' gestation, who were given 60mg of DHA/kg per day via enteral or control tube feeding. They were compared with 333 children in the control group, who received an emulsion with no DHA. At five years old, children in both groups underwent the Wechsler Preschool and Primary Scale of Intelligence (WPPSI) IQ test. “On average, those in the DHA group scored 3.5 points higher on the IQ scale than those in the control group,” Dr. Gould said. “These very promising results suggest DHA has the potential to improve cognitive performance when administered via emulsion for infants born before 29 weeks' gestation.” Crossword puzzles beat computer video games in slowing memory loss Columbia University Irving Medical Center & Duke University, October 27, 2022 A new study by researchers from Columbia University and Duke University published in the journal NEJM Evidence shows that doing crossword puzzles has an advantage over computer video games for memory functioning in older adults with mild cognitive impairment. In a randomized, controlled trial, led by D.P. Devanand, MD, professor of psychiatry and neurology at Columbia, with Murali Doraiswamy, MD, professor of psychiatry and medicine at Duke, researchers determined that participants (average age 71) trained in doing web-based crossword puzzles demonstrated greater cognitive improvement than those who were trained on cognitive video games. “This is the first study to document both short-term and longer-term benefits for home-based crossword puzzles training compared to another intervention,” said Dr. Devanand, who oversees brain aging and mental health research at Columbia. “The results are important in light of difficulty in showing improvement with interventions in mild cognitive impairment.” To conduct their study, researchers at Columbia and Duke randomly assigned 107 participants with mild cognitive impairment (MCI) at the two different sites to either crossword puzzles training or cognitive games training with intensive training for 12 weeks followed by booster sessions up to 78 weeks. Both interventions were delivered via a computerized platform with weekly compliance monitoring. The most striking findings of the trial were: Crossword puzzles were superior to cognitive games on the primary cognitive outcome measure, ADAS-Cog, at both 12 weeks and 78 weeks. Crossword puzzles were superior on FAQ, a measure of daily functioning, at 78 weeks. Crossword puzzles were superior for participants at a later disease stage but both forms of training were equally effective in an earlier stage. Brain shrinkage (measured with MRI) was less for crossword puzzles at 78 weeks. “The benefits were seen not only in cognition but also in daily activities with indications of brain shrinkage on MRI that suggests that the effects are clinically meaningful,” Dr. Devanand said. The study also highlights the importance of engagement. Based on remote electronic monitoring of computer use, participants at a later stage of impairment may have better engaged with the more familiar crossword puzzles than with computerized cognitive games. Atherosclerosis, ED, low vitamin D levels linked Guizhou Medical University (China), October 24 2022. A study published in Frontiers in Endocrinology evaluated the associations between lower serum levels of vitamin D, erectile dysfunction (ED) and an increased risk of atherosclerosis. The investigation included 163 men aged 30 to 60 years who received physical examinations at the Affiliated Hospital of Guizhou Medical University. Fasting blood samples were analyzed for serum 25-hydroxyvitamin D and other factors. Carotid intima-media thickness, an indicator of atherosclerosis in the carotid arteries, was measured using ultrasound. International index of erectile function-5 (IIEF-5) scores were graded as mild, moderate or severe according to ED severity. Thirty-nine participants whose IIEF-5 scores indicated no ED served as control subjects. Serum vitamin D levels were lower and carotid intima-media thickness values were higher among men with moderate and severe ED compared to the control group. Carotid intima-media thickness was significantly higher among men with severe ED compared with those who had mild ED. After adjustment, significant correlations were found between IIEF-5 scores, carotid intima-media thickness and serum 25-hydroxyvitamin D. In their discussion, authors Jun-hao Zhang of Soochow University and colleagues remarked that vitamin D may affect erectile function via its interaction with the endothelial cells of the corpora cavernosa, which is the spongy tissue within the penis that fills with blood during an erection. Vitamin D may affect the production and release by endothelial cells of nitric oxide, a compound that helps relax the blood vessels, thereby improving erectile function. The vitamin may also help decrease damage to endothelial cell function caused by oxidative stress. “Serum vitamin D level should be analyzed in men with ED, especially in patients with vasculogenic ED, and supplementation is recommended for those who were with vitamin D deficiency,” the authors wrote. Carnitine supplementation could improve cold tolerance and more University of Utah, October 23 2022 Cell Metabolism reported research findings from the University of Utah School of Medicine that reveal a role for carnitine in the body's response to cold temperatures. “Cold-induced thermogenesis is an energy-demanding process that protects endotherms against a reduction in ambient temperature,” Judith Simcox, PhD, and colleagues write. “We found that the liver undergoes a metabolic switch to provide fuel for brown fat thermogenesis by producing acylcarnitines.” “Cold stimulates white adipocytes to release free fatty acids that activate the nuclear receptor HNF4α, which is required for acylcarnitine production in the liver and adaptive thermogenesis,” they continue. “Once in circulation, acylcarnitines are transported to brown adipose tissue, while uptake into white adipose tissue and liver is blocked.” Acylcarnitines are fatty acyl esters of L-carnitine that were found to increase in young mice during cold adaptation. “It was surprising to see acylcarnitines in the bloodstream,” Dr Simcox remarked. With aging comes a decline in the ability to adapt to cold exposure. In the current study, researchers found that a single dose of L-carnitine or palmitoylcarnitine improved aging-related cold sensitivity in mice. Because activating cold adaptation burns calories, improving the process be useful for more than the ability to tolerate cold environments. Feeling chirpy: Being around birds is linked to lasting mental health benefits King's College London, October 27, 2022 New research from King's College London has found that seeing or hearing birds is associated with an improvement in mental well-being that can last up to eight hours. This improvement was also evident in people with a diagnosis of depression—the most common mental illness worldwide—indicating the potential role of birdlife in helping those with mental health conditions. Lead author Ryan Hammoud, Research Assistant at the Institute of Psychiatry, Psychology & Neuroscience (IoPPN), King's College London, said: “There is growing evidence on the mental health benefits of being around nature and we intuitively think that the presence of birdsong and birds would help lift our mood. However, there is little research that has actually investigated the impact of birds on mental health in real-time and in a real environment. The study took place with 1,292 participants completing 26,856 assessments. Participants were recruited worldwide. The app asked participants three times a day whether they could see or hear birds, followed by questions on mental well-being to enable researchers to establish an association between the two and to estimate how long this association lasted. Researchers showed that the links between birds and mental well-being were not explained by co-occurring environmental factors such the presence of trees, plants, or waterways. Our study provides an evidence base for creating and supporting biodiverse spaces that harbor birdlife, since this is strongly linked with our mental health. In addition, the findings support the implementation of measures to increase opportunities for people to come across birdlife, particularly for those living with mental health conditions such as depression.”

It's very easy to get stuck in a mindset of “I've chosen THIS thing, so all other things are off the table, because once you choose THIS thing, then THESE are the things I HAVE to do." But who says we have to? Dr Tanya Stephens' career is that it's not just one thing. Her story clearly demonstrates that you don't HAVE to do anything in a certain way. Clinical practice doesn't have to take up all your time and exclude other interests. Practice ownership doesn't have to be a ball and chain. Having young kids doesn't have to mean you can't run a business. Research doesn't have to be done just by 'researchers'. Dr Tanya Stephens is a small animal practice owner and practitioner who still very much enjoys practice. As a practitioner, she is particularly interested in professional ethics and promoting evidence-based medicine. She is also a wildlife researcher with original research on galactosaemia in kangaroos. Her interests lie in animal welfare, research, evidence-based medicine, professional ethics, wildlife and sustainable agriculture and she is a regular presenter and published author on these topics. She is the editor of One Welfare in Practice: the Role of the Veterinarian and is a Fellow of the Royal College of Veterinary Surgeons. Tanya is past President of the ANZCVS Animal Welfare Chapter, past President of AVAWE, the welfare and ethics branch of the AVA, an exec member of AVCB, which is the Conservation Biology branch of the AVA, Chair of the AVA's Animal Welfare Trust, honorary consulting veterinarian for the Children's Medical Research Institute, veterinary member of the NSW Civil and Administrative Tribunal, Chair of the NSW Kangaroo Management Advisory Panel and member of the Kangaroo Management Taskforce plus the Chair of the NSW Greyhound Welfare Integrity Commission Animal Welfare Committee. Jump in with us to hear how Tanya followed her curiosity to create a career around what worked for her. Of course, we also talk about ethics and the line between thorough and too much, trust, and why Tanya thinks we might be losing it, the perils of defensive practice, the concept of "gold standard" and why aiming for it might not always be the best idea, how YOU play a key role in animal welfare in your consult room and beyond, and much much more. Go to thevetvault.com for show notes and to check out our guests' favourite books, podcasts and everything else we talk about in the show. If you want to lift your clinical game, go to vvn.supercast.com for a free 2-week trial of our short and sharp highly practical clinical podcasts, or join us live and in person in Noosa from 22-25 November for our first ever Vet Vault Live! with Prof David Church and Prof Jill Maddison. We love to hear from you. If you have a question for us or you'd like to give us some feedback please get in touch via email at thevetvaultpodcast@gmail.com, or just catch up with us on Instagram. And if you like what you hear then please share the love by clicking on the share button wherever you're listening and sending a link to someone who you think should hear this. --- Send in a voice message: https://anchor.fm/vet-vault/message

Proteomics; the study of all the proteins contained in our tissues and a potential cancer treatment   Dr Steve Williams is a research officer from the Children's Medical Research Institute. He has a PhD in Medicinal Medicine from UTS with experience in analytical chemistry. The Children Medical Research Institute (CMRI), based in Westmead, is focused on children's genetic diseases.   In this episode, Pete sits down with Dr Steve Williams from the Children's Medical Research Institute (CMRI) as they focus on genetic conditions that affect children. Together, they explore the world of proteomics and its potency as a future treatment for cancer.   Cancer is becoming increasingly common, which increases the need for more innovative and efficient treatment modalities. This episode explores one such treatment; proteomics. Learn about what it is and how it can help with the management of diseases. Check out the episode and full show notes here. Loving the show?  Leave us a review, and share it with some friends, and let us know how we can improve by completing our podcast listener survey. Keen to take your healthtech to the next level? Become a THT+ Member for access to our online community forum, quarterly summits and more exclusive content.  For more information visit here.

The Masonic Medical Research Institute is an internationally recognized biomedical research institute founded by the Grand Lodge of Free and Accepted Masons in the State of New York in 1958. RW Imbimbo, Bro. Cucci and Dr. McCarthy share what makes this facility unique, not just in Freemasonry, but in the important research they conduct.Show Links...Visit the Masonic Medical Research Institute online... https://www.mmri.edu/Want to tour the MMRI in Utica? Contact Bro. Anthony Cucci at acucci@mmri.eduVisit RW Pat Imbimbo's family farm (Slate Valley Farms) - we HIGHLY recommend the Beeswax Lotion... https://www.slatevalleyfarms.com/

Matthew Iasiello is a Researcher and Project Co-ordinator at the South Australian Health and Medical Research Institute. Matthew is also a PhD candidate at Flinders University, whose PhD focuses on the relationship between mental health and mental wellbeing. This clip is part of an episode of The Mental Wellbeing Show titled "Mental Wellbeing Strategies"

Matthew Iasiello is a Researcher and Project Co-ordinator at the South Australian Health and Medical Research Institute. Matthew is also a PhD candidate at Flinders University, whose PhD focuses on the relationship between mental health and mental wellbeing. In this episode of The Mental Wellbeing Show, we discuss what mental wellbeing is, why it matters to everyone regardless of mental illness status, and strategies anyone can implement to improve their own mental wellbeing. 0:00 Intro 0:15 Dual-continua model of mental health 4:34 What is mental wellbeing? 8:44 Having low mental wellbeing 11:58 Effective interventions for your mental wellbeing 15:19 Finding the best intervention for you 19:01 The Be Well Plan 20:20 Examples of mental wellbeing strategies 26:46 Impacting mental wellbeing at scale 28:37 Matt's recommendations on mindfulness Further reading on resources and studies mentioned in this episode: New York Times article on mental wellbeing: https://www.nytimes.com/2021/04/19/we.... Image outlining the Dual Continua Model of Mental Health: https://opentextbc.ca/mhwframework/ba... The Be Well Plan: https://www.bewellco.io/ "A systematic review and meta-analysis of psychological interventions to improve mental wellbeing" (2021) by van Agteren et. al. "The protective effects of wellbeing and flourishing on long-term mental health risk" (2022) by Burns et. al. "A facilitated, Internet-based intervention to promote mental health and wellbeing in a vulnerable population of university students: randomised controlled trial of the Be Well Plan" (2022) by Fassnacht et. al.

An invisible problem is plaguing the lives of one in ten adult females, and the health system is not making it easy for them. Endometriosis is a condition where tissue from inside the womb grows in other places in the body - an extremely painful condition which in many cases requires surgical removal. But the Medical Research Institute says on average people need to see five doctors before they’re believed, and have to wait an average 8.7 years after the first symptoms arise to be formally diagnosed. Joining us is Endometriosis NZ CEO Tanya Cooke. See omnystudio.com/listener for privacy information.

Danielle Borg is the program coordinator for the Queensland Family Cohort Study at the Mater Research Institute. Here she talks us through the large scale project, as well as her career journey and trying to manage work and life!

Vol 216, Issue 7: 11 April 2022. Associate Professor Luke Grzeskowiak is a clinical pharmacist and Practitioner Fellow at Flinders University and the South Australian Health and Medical Research Institute. He talks about hormonal contraceptive use following early medical abortion, to accompany his coauthored research letter published in the MJA. With MJA news and online editor Cate Swannell.

Dr. Emilio A. Emini, Ph.D. is the CEO of the Bill & Melinda Gates Medical Research Institute (https://www.gatesmri.org/), a non-profit organization dedicated to the development and effective use of novel biomedical interventions addressing substantial global health concerns, for which investment incentives are limited, and he leads the Institute's research and development of novel products and interventions for diseases disproportionately impacting the world's most vulnerable populations. Before joining the Gates MRI, Dr. Emini served as director of the HIV and Tuberculosis program at the Bill & Melinda Gates Foundation, where he led the foundation's efforts focused on accelerating the reduction in the incidence of HIV and TB in high-burden geographies, with the goal of achieving sustained epidemic control. Over the course of his previous 30-year career in the bio-pharmaceutical industry, Dr. Emini led teams involved in the research and development of novel anti-infectives and vaccines. From 1983 to 2004, he led research at the Merck Research Laboratories involved in the development of one of the first highly active anti-retroviral therapies for HIV and, as senior vice president of vaccine research, the successful development of a number of vaccines including vaccines for human papillomavirus and rotavirus. Dr. Emini later served as senior vice president of vaccine development at the International AIDS Vaccine Initiative. From 2005 to 2015, he was senior vice president of vaccine R&D at Pfizer Inc., leading the development of Prevnar 13® for prevention of pneumococcal disease. Dr. Emini was awarded the Distinguished Alumnus Award from the Weill Cornell University Graduate School of Medical Sciences in 2006. He is a former trustee of the National Foundation for Infectious Diseases and a former member of the National Preparedness & Response Science Board, an advisory committee to the U.S. Secretary of Health and Human Services. He is an elected fellow of the American Academy of Microbiology, International Society for Vaccines, and The College of Physicians of Philadelphia. He received his Ph.D. in Microbiology, Genetics, and Biochemistry from the Weill Cornell University Graduate School of Medical Sciences.

A community health clinic in Auckland says during last year's Delta outbreak, it became the default provider of medical and welfare care for self-isolating patients, because the Ministry of Health was failing to provide adequate care. Papakura Marae Health Centre serves a community of more than 3,200 people, with at least 95 percent identifying as Maori or Pasifika. When the government moved to a mixed MIQ and Community Supported Isolation and Quarantine (CIQ) model, the Ministry of Health contracted Whakarongorau Aotearoa to carry out a remote check-in service for patients. However the Papakura Marae Health Centre soon observed issues with the service, including reports of whanau isolating in unsafe homes and a failure to consistently perform timely check-ins and reviews. The Papakura Marae Health Centre decided to step in and take over the role of the Ministry of Health's system. Kathryn Dr Matire Harwood is a GP at the Papakura Marae Health Centre. She is also Associate Professor at the University of Auckland and senior researcher at the Medical Research Institute of New Zealand.

ICU specialist Professor Paul Young says it's time to rethink the well-established use of saline intravenous fluids for critically ill patients in hospital. He says extensive research shows an alternative therapy, called balanced crystalloids, saves more lives than saline. Saline has been widely used in medicine for the last 200 years, but has not undergone the rigorous testing applied to new drugs. ICU and emergency doctors have long debated the relative benefits of saline versus balanced crystalloids; a salt-based solution with an electrolyte composition that mimics plasma. Professor Young says the results of new research by the Medical Research Institute of New Zealand is the final piece of the puzzle, and when combined with data from other clinical trials, shows that for acutely unwell patients, using balanced crystalloids rather than saline, saves lives. The results of the study, published in the New England Journal of Medicine, is expected change clinical practice in intensive care settings worldwide. Kathryn speaks with Professor Paul Young, who is the deputy director at the Medical Research Institute of New Zealand and the leader of the study.

What are some of the challenges women still face today in getting access to good healthcare and education opportunities throughout the world? How can physicians broaden their conception of what impact really means? In this episode, we answer all these questions and more with our guest, Claire Wagner, MD. Claire is head of corporate strategy at Bill & Melinda Gates Medical Research Institute, a global health biotech dedicated to developing pharmaceutical products for some of the world's most complex diseases. Claire has an MD from Harvard Medical School and an MBA from Harvard Business School, where she was the Commencement Class Day Speaker.

A new study has found that self-rehabilitation after a stroke could make a significant difference to recovery outcomes for patients. Dr Harry McNaughton has been leading the research for the Medical Research Institute of New Zealand, which involves a talking therapy programme called Take Charge. It encourages people recovering from a stroke to focus on what, and who, is most important to them in order to best plan their own rehabilitation. If the programme was implemented across New Zealand, it's estimated that an additional 600 people would be independent 12 months after their stroke for basic activities like walking, showering, and dressing. As a low cost solution it's also expected to save the health system upwards of $9 million each year. The findings of the study have recently been published in the international journal, Clinical Rehabilitation. Kathryn speaks to the MRINZ Stroke Rehabilitation Research director, Dr Harry McNaughton.

“We would like to acknowledge that this conversation was recorded on the traditional lands of the Wurundjeri people and pay my respect to Elders both past, present and future.”Our guest Rachel Reilly lives and work on Kaurna Country, and pays her respects to Elders past, present and emerging.We would also like to acknowledge the cultural authority of my Aboriginal and Torres Strait Islander colleagues who have led this project, and provided guidance and support for me throughout.The project team comprises a team of Aboriginal and non-Aboriginal researchers with an extraordinary depth of knowledge. Their bios are on the NIMAC website below.Lastly, we acknowledge and thank the participants in the research, who by generously sharing their knowledge have enabled this project to exist.In this episode, we chat with Rachel Reilly who is a senior research fellow from the South Australian Health and Medical Research Institute about her work in Aboriginal health and the development and research of an app to help Aboriginal and Torres Strait Islander people with the harmful impacts of Ice use. Rachel & Jack are not Aboriginal and have sort the blessing to publish this conversation from Professor James Ward, who is a Pitjantjatjara and Nukunu man and lead researcher on this project. Professor James Ward is a Pitjantjatjara and Nukunu man, an infectious diseases epidemiologist and a national leader in Aboriginal and Torres Strait Islander research. He is currently the Director of the Poche Centre for Indigenous Health at The University of Queensland.Holding various roles over the last 25 years in Aboriginal public health policy for both government and non-government organisations, in urban regional and remote communities he has built a national program of research in the epidemiology and prevention of infectious diseases, with a particular focus on STIs, HIV and viral hepatitis in Aboriginal and Torres Strait Islander communities.Professor Ward has previously worked at the Kirby Institute, University of New South Wales, Baker IDI in Alice Springs and the South Australian Health and Medical Research Institute. He has served on numerous national and international committees including currently the Communicable Diseases Network of Australia, the Australian National Council on Alcohol and Drugs, the CDNA COVID-19 Working Group and the Aboriginal and Torres Strait Islander COVID-19 Taskforce. He has over 120 publications and leads several large scale public health and infectious diseases studies.   Links to the project and other helpful information. Project website:www.wecandothis.com.au www.nimac.org.au https://www.facebook.com/1wecandothis For service providers interested in using the app with clients, and providing feedback to us: Contact me: rachel.reilly@sahrmi.com Social determinants: Broadly, social determinants are the circumstances in which people grow, live, work and age (WHO 2008). ... For Aboriginal and Torres Strait Islander people, the social determinants of health also include factors such as cultural identity, family, participation in cultural activities and access to traditional lands. I've attached a poster that summarises some of the findings from our conversations with people about their experiences with methamphetamine. A summary of intergenerational trauma narrated by Jack Charles is here:https://www.youtube.com/watch?v=Y-RaB19D13E The US research on Adverse Childhood Events is summarised here:https://www.cdc.gov/violenceprevention/aces/index.htmlIt includes a neat little YouTube video on the site that gives a nice summary. Info sheet on trauma-informed services for Aboriginal and Torres Strait Islander people (Judy Atkinson):https://earlytraumagrief.anu.edu.au/files/ctg-rs21.pdfhttps://aifs.gov.au/cfca/2013/08/13/growing-our-children-up-strong-and-deadly-healing-for-children-and-young-people-2 _________________________We have a new book! Grab the Special Offer here: https://www.connectionbasedliving.com/11STEPSBOOKIf you or a loved one needs help beating addiction, you can visit www.connectionbasedliving.com.au If you want to check out more about Real Drug Talk & Everything we do you can visit us at our website, www.realdrugtalk.com.au We would love it if you followed us on social media to keep supporting the message. Our social media handle is @realdrugtalk on socials. 

Dr Yasmine Probst is a Dietitian and an Associate Professor currently based at the University of Wollongong and a Research Fellow with the Illawarra Health and Medical Research Institute. Yasmine is also a person living with MS. Listen in to hear which foods are best to eat, and why, when living with MS.

A chat with Alexandra Emerson (Cook) about all sorts of things, but mainly her experience with infertility and premature birth, and how faith works in her life. Alexandra is walking 50km in 10 days during September for SAHMRI (South Australian Health and Medical Research Institute) to raise funds for research into preterm babies, her son Darcy having been born 6 weeks early. If you'd like to sponsor her walk, here is a link:https://my.sahmribright.org.au/alexandra-emerson

Michael is a Co-founder of Tide Foundation, a deep tech start-up developing technology to enable cyber-herd immunity. He's a seasoned entrepreneur with a rich history leading the development and go-to-market of enterprise software. He spent over a decade growing a decorated digital agency before merging to become a full services agency and successfully exiting. Michael holds a degree in Information Systems and Accounting, UNSW; was an academic professional at the University of Illinois and currently serves on the advisory board of the Children's Medical Research Institute.

If you're not sleeping well, you're not performing to your full potential. Investing in rest is one of the best things you can do. But how? The best person to help you appreciate and improve your sleep as a foundation for improvement in every aspect of your life is today's guest, Professor Danny Eckert, who is recognised as one of the world's leading experts on sleep. Professor Eckert has been actively involved in human sleep and respiratory physiology research for over 20 years. He is a National Health and Medical Research Council of Australia Senior Research Fellow and Mathew Flinders Professor at Flinders University in South Australia.  Danny currently serves as Director of the Adelaide Institute for Sleep Health and Deputy Director at the Flinders Health and Medical Research Institute.  He leads a comprehensive research program that focuses on identification of the causes of sleep apnea, optimisation of existing therapies, and development of new tailored therapies.  He is most well-known for his pioneering respiratory work which has led to a new precision medicine therapeutic framework to understand and treat sleep apnea, and for his research on the role of arousal mechanisms on sleep apnea. He has published more than 150 articles in the leading sleep and respiratory medical journals.  Danny's previous appointments include Professor of Medicine at the University of New South Wales in Sydney, Principal Research Scientist at Neuroscience Research Australia and Assistant Professor within the Division of Sleep Medicine, Brigham and Women's Hospital at Harvard Medical School in Boston. So in this eye opening and insightful discussion, Danny answers all of your sleep questions, including: What is good quality sleep? What happens to us when we sleep? Why is sleep so important? What are the benefits of good sleep? How much sleep do we need? What are the impacts if we undersleep or oversleep?  How do our iPhones, TVs and other devices affect our sleep? What is the relationship between sleep and breathing? What impact does meditation and napping have on sleep and its benefits?  What impact does sleep have on our mental health, mood, depression, body organs, performance, memory, creativity, weight and immune system? Can we recover from the ill effects of prolonged sleep deprivation?   What do we need to do and what not to do to optimise sleep and its benefits? How do we need to set up our sleep environment and sleep routine? What position should and shouldn't we sleep in? And the growing epidemic of Sleep Apnea: What is it? The risk factors, effects, and what can you do about it. This is a really informative discussion that definitely won't put you to sleep! But if you're looking for a good book to read before you grab some well earned zzzz's, you can grab a free copy of my award winning book ‘Get Invested', which is the prequel to my book The Freedom Formula, by going to https://bushymartin.com.au/books Get Invested is the leading weekly podcast for Australians who want to learn how to unlock their full ‘self, health and wealth' potential. Hosted by Bushy Martin, an award winning property investor, founder, author and media commentator who is recognised as one of Australia's most trusted experts in property, investment and lifestyle, Get Invested reveals the secrets of the high performers who invest for success in every aspect of their lives and the world around them. Remember to subscribe on your favourite podcast player, and if you're enjoying the show please leave us a review. Find out more about Get Invested here https://bushymartin.com.au/get-invested-podcast/  Want to connect with Bushy? Get in touch here https://bushymartin.com.au/contact/  This show is produced by Apiro Media - http://apiropodcasts.com

New research into post-cardiac arrest care has turned treatment advice on its head and will lead to significant clinical changes in intensive care units in New Zealand and internationally. A study found that cooling survivors of cardiac arrest to below a normal body temperature does not improve patient survival or recovery. Therapeutic hypothermia has been a cornerstone of ICU treatment globally for the past 20 years and is part of standard care to limit brain damage. Kathryn speaks with Professor Paul Young, deputy director at the Medical Research Institute of New Zealand and the lead New Zealand investigator on the study, which was published last week in the New England Journal of Medicine.

New research into post-cardiac arrest care has turned treatment advice on its head and will lead to significant clinical changes in intensive care units in New Zealand and internationally. A study found that cooling survivors of cardiac arrest to below a normal body temperature does not improve patient survival or recovery. Therapeutic hypothermia has been a cornerstone of ICU treatment globally for the past 20 years and is part of standard care to limit brain damage. Kathryn speaks with Professor Paul Young, deputy director at the Medical Research Institute of New Zealand and the lead New Zealand investigator on the study, which was published last week in the New England Journal of Medicine.

In this episode, Springworks' Head of Marketing, Abhash Kumar talks to Yvonne Wolf,  Founder and Chief Collaborator, TalentMatters LLC. Yvonne has 25+ years of broad industry experience, partnering with boards and executive teams, influencing strategy, governance, talent, and culture decisions.She is a graduate of Northern Illinois University and holds a degree of Bachelor of Science in Advertising from the School of Business and Journalism. Yvonne crafted the board-approved HR strategy at Bill & Melinda Gates, Medical Research Institute for the 2020-2024 Strategic Plan. This strengthened the HR practices and team of this growing non-profit, biotech start-up. In the episode, she talks about how organizations made changes in their management strategies due to the pandemic. She also throws light on the topics of diversity and inclusion, and how organizations should go about taking democratic decisions while drawing the line.Organizational change management principlesYvonne shares the three important principles she learned about change management while working at Partners in Health.Democratic decision-making vs drawing the lineYvonne has worked in organizations varying from 100 employees to 100,000 employees. She suggests that the practice of asking people what they need should happen in all organizations. It does not take away the leaders' responsibility to make decisions. However, decision-making should be done differently in a small organization versus a large organization. For example, an organization with 180 people might have 6 to 7 middle managers who can influence the team. Here the decision-making process is short. However, with a large company with 1,000,000 employees, the number of middle managers has to be more.A curious and open-minded listening leader is the core of a successful decision-making process irrespective of the size of the organization. Hence, a leader's responsibility is to decide after getting opinions and ideas from multiple people.People manager's role in influencing leaders for the transformation“It is incumbent upon leadership to create an environment that says. All lives matter, all opinions matter, all talent matters. And I think it's incumbent upon HR to create systems and processes that produce that outcome.” Back in the day, people were a little more mindful of hierarchy. If someone in the team was 12 layers below, they wouldn't dare approach the CEO. Yvonne loves today's social media culture and how people feel they have every right to send a note right to the CEO about things that bother them. CEOs and leaders need to ensure that kind of openness everywhere in order to avoid affecting the employer brand. Thoughts on banning employees' political thoughts at workThe highest place for trust is in the workplace. Thus to ban conversations would be to ask people to leave a part of themselves. And it is also a missed opportunity to have some necessary and insightful conversations. According to Yvonne, the actual challenge is to promote civility in the conversation.Yvonne suggests teaching employees how to have conversations. They need to build that curiosity for the conversation while having some ground rules at the same time.Traits of a good leaderInclusion, curiosity, empathy, and compassion- are the qualities of a good leader. Regardless of what's happening in the world, Yvonne believes that these qualities are the factors that are going to be the difference between organizations that can both predict or navigate.Follow Yvonne on LinkedInProduced by: Priya BhattPodcast host: Abhash Kumar

It was truly a pleasure speaking with representatives of the Masonic Medical Research Institute (MMRI). The representatives are: R.: W.: Robert A. Hewson, DPM – President, Board of Directors R.: W.: James D. Swan, Jr. – Secretary, Board of Directors Bro. Anthony F. Cucci – Fraternal Relation & Development Associate All of the above are active Masons within (and without) the jurisdiction of New York Grand Lodge. You can learn more about MMRI by going to the website: https://mmri.edu/ or by contacting Bro. Cucci at: acucci@mmri.edu. All opinions expressed are those of Square & Compass Promotions and the guest(s), and do not necessarily reflect the opinions of the Grand Lodge of Canada in the Province of Ontario and/or the Windsor Masonic Temple.

In Episode 17, Season 3 of the Amplifying Scientific Innovation Video Podcast, Dr. Sophia Ononye-Onyia, Founder and CEO of The Sophia Consulting Firm, interviewed Dr. Russell Weiner, Head Bioanalysis, Biomarker Development and Diagnostics at the Bill & Melinda Gates Medical Research Institute. Here, Dr. Weiner shares anecdotes of his scientific leadership journey, industry outlook and his organization's focus on accelerating the product development timeline for diseases that disproportionately affect the world's poorest populations, starting with malaria, tuberculosis, and diarrheal diseases—diseases that combined cause five deaths every minute. For full transcript, please visit: https://sophiaconsultingfirm.com/blogs-and-articles/f/amplifying-scientific-innovation-dr-russ-weiner-head-gates-mri

Vitamin A derivative selectively kills liver cancer stem cells  RIKEN Center for Integrative Medical Science (Japan), April 23, 2021 Acyclic retinoid, an artificial compound derived from vitamin A, has been found to prevent the recurrence of hepatocellular carcinoma (HCC), the most common form of liver cancer. Now, in research published in Proceedings of the National Academy of Sciences, scientists have discovered that the compound targets one class of cancer stem cells, preventing them from giving rise to new tumors. HCC is a highly lethal cancer, which causes approximately 600,000 deaths each year around the world, making it the second deadliest cancer after non-small cell lung cancer. One of the reasons for the high lethality is that it has a high rate of recurrence—surgery and other treatments are initially effective, but the cancer often relapses. As a result, researchers have looked for ways to prevent recurrence, and acyclic retinoid was recently found to be effective in stopping recurrence of tumors. However, scientists were not sure exactly why it worked. To find clues, a research group led by Soichi Kojima of the RIKEN Center for Integrative Medical Science looked at the transcriptome of cells that had been exposed to acyclic retinoid, and found that compared to control untreated cells, they had low expression of MYCN, a gene that is often expressed in tumors and is correlated with poor prognosis. Further experiments, which involved deliberately repressing the expression of the gene in cancer cells, showed that the reduction in MYCN expression led functionally to slower cell-cycle progression, proliferation, and colony formation, and to greater cell death, implying that the action of the acyclic retinoid on MYCN was slowing the cancer growth. The group then focused on the role of "cancer stem cells"—special cells that are able to survive the onslaught of chemotherapy or other treatments and to then differentiate into new cancer cells, leading to recurrence. They found, indeed, that high expression of MYCN was correlated with the expression of a number of markers that are associated with cancer stem cells. "The most interesting part of our finding," says Kojima, "is when we then looked at different subpopulations of heterogeneous cancer cells. We found one specific group of EpCAM-positive cancer stem cells, where MYCN was elevated. We wondered if perhaps the key to acyclic retinoid's effect was its ability to target these hepatic cancer stem cells." Indeed, experiments revealed that when exposed to acyclic retinoid, in a dose dependent manner, the EpCAM-positive cells were selectively depleted. To test whether this had clinical significance, they took liver biopsies of patients who had been given acyclic retinoid following liver cancer surgery, and found that in four of the six who had received a higher dosage of 600 mg/d but rather than 300 mg/d, there were decreased levels of MYCN expression, suggesting that MYCN expression in response to acyclic retinoid could be an important part of the difference in recurrence seen in trials. Finally, they looked at data from the Cancer Genome Atlas, and found that elevated expressionof MYCN correlated with dramatically poorer prognosis. According to Kojima, "It is remarkable that the acyclic retinoid clearly targets a certain category of cancer stem cells, and this provides us with important hints for decreasing cancer recurrence and truly curing patients. We are waiting to see what clinical data will show us." A phase 3 clinical trial of acyclic retinoid (also called Peretinoin), is currently underway in Korea, Taiwan and Singapore to test the drug's ability to prevent HCC recurrence.     Light up your mind: A novel light-based treatment for neurodegenerative diseases Researchers review growing knowledge on the methods and applications of light therapy in treating neurodegenerative diseases Soochow University (China), April 2021 A lot about the human brain and its intricacies continues to remain a mystery. With the advancement of neurobiology, the pathogenesis of several neurodegenerative diseases (ND) has been uncovered to a certain extent, along with molecular targets around which current therapies revolve. However, while the current treatments offer temporary symptomatic relief and slow down the course of the disease, they do not completely cure the condition and are often accompanied by a myriad of side effects that can impair normal daily functions of the patient. Light stimulation has been proposed as a promising therapeutic alternative for treating various ND like Alzheimer's disease (AD), Parkinson's disease (PD), cognitive and sleep disorders. Light therapy consists of controlled exposure to natural daylight or artificial light of specific wavelengths. While neurologists worldwide have begun testing its use in clinical practice, less remains understood about the mechanisms behind how light affects neurological function. Thus, in a review article now published in Chinese Medical Journal, researchers from China comprehensively summarize the growing knowledge on the mechanism of action, effectiveness, and clinical applications of LT in the treatment of ND. Neurologist and author Dr. Chun-Feng Liu explains how their work can advance our understanding of novel emerging therapies for ND. "While light therapy has been investigated in mental and sleep disorders, comprehensive knowledge on its use in neurodegenerative diseases in lacking. We therefore sought to shed light on the potential therapeutic methods and implications of light therapy," he states. Our body function is tuned to a circadian or day and night rhythm. The clock that controls this rhythm is housed in the hypothalamus region of the brain. The genes expressed in this region are crucial in maintaining the circadian rhythm. Thus, a malfunction of these genes can disrupt the rhythmic cycle. These defects have been associated with neurodegenerative, metabolic and sleep disorders. External stimuli such as light, physical activity and food intake can help reset the clock and restore normal circadian rhythms, thus alleviating symptoms. Another mechanism by which the clock controls circadian rhythms is through the secretion of the melatonin (MT) hormone. MT secreted by the pineal gland in the brain is known to control sleep patterns as it is secreted in higher amounts in the night than the day. Light stimulation in this case suppresses the secretion of MT during the day time and thus reduces drowsiness. Interestingly, different tissue and organs in the body may respond differentially to light stimulation. Furthermore, different biomolecules expressed in circulating immune cells and stem cells are sensitive to specific wavelengths of light and thus elicit different responses by promoting the secretion of neurotrophic factors that can rescue neuronal functions. Next, the researchers go on to discuss the application of light stimulation in specific neurodegenerative disorders. In case of AD, a progressive dementia, sleep disturbance has been associated with an increased expression of biomarkers that promote disease progression. Patients with AD often experience confusion, emotional distress and hyperactivity after dusk and through the night. Preliminary clinical studies on AD mouse models as well as patients with AD suggest that light stimulation helps restore memory and cognition and decreases the burden of the pathogenic amyloid-β protein in the brain. Furthermore, LT has been shown to improve sleep quality and duration in patients with sleep disorders while bright environments help reduce anxiety and aggressive behaviors in patients with dementia. In case of PD, patients suffer from motor impairment, tremors and posture imbalance and also display non-motor symptoms such as insomnia, depression and fatigue that can collectively impair their quality of life. While LT has been shown to decrease non-motor symptoms to some extent, evidences on its direct benefits towards motor-function however are limited. The use of LT in other neurodegenerative disorders is currently at preclinical stages and needs to be pursued further. Overall, LT offers a safe and cost-effective alternative for treatment of ND. Additional studies and large scale clinical trials in this direction can help establish its effectiveness as a potential therapeutic strategy. Explaining the long term clinical applications of LT, Dr. Liu says, "The light box or light therapy lamp will help improve the sleep quality of patients with sleep disorders. Light stimulation will also likely have therapeutic effects on neurodegenerative diseases and seasonal depression. Further studies are needed to elucidate its effectiveness." This review not only advances our understanding on how LT functions in resetting the circadian rhythm and associated neurological symptoms but also highlights its applications in routine clinical practice.   Bad to the bone: Hebrew University reveals impact of junk food on kids' skeletal development Study provides first comprehensive analysis for how junk foods impact skeletal development. Hebrew University of Jerusalem, April 19, 2021 A team of researchers from the Hebrew University of Jerusalem has proven the linkages between ultra-processed foods and reduced bone quality, unveiling the damage of these foods particularly for younger children in their developing years. The study, led by Professor Efrat Monsonego-Ornan and Dr. Janna Zaretsky from the Department of Biochemistry, Food Science and Nutrition at the University's Faculty of Agriculture, was published in the journal Bone Research and serves as the first comprehensive study of the effect of widely-available food products on skeleton development. Ultra-processed foods--aka, junk food--are food items products that undergo several stages of processing and contain non-dietary ingredients. They're popular with consumers because they are easily accessible, relatively inexpensive and ready to eat straight out of the package. The increasing prevalence of these products around the world has directly contributed to increased obesity and other mental and metabolic impacts on consumers of all ages.  Children tend to like junk food. As much as 70% percent of their caloric consumption are estimated to come from ultra-processed foods. While numerous studies have reflected on the overall negative impact of junk food, few have focused on its direct developmental effects on children, particularly young children. The Hebrew University study provides the first comprehensive analysis for how these foods impact skeletal development. The study surveyed lab rodents whose skeletons were in the post embryonic stages of growth. The rodents that were subjected to ultra-processed foods suffered from growth retardation and their bone strength was adversely affected. Under histological examination, the researchers detected high levels of cartilage buildup in the rodents' growth plates, the "engine" of bone growth. When subjected to additional tests of the rodent cells, the researchers found that the RNA genetic profiles of cartilage cells that had been subjected to junk food were showing characteristics of impaired bone development.  The team then sought to analyze how specific eating habits might impact bone development and replicated this kind of food intake for the rodents. "We divided the rodents' weekly nutritional intake--30% came from a 'controlled' diet, 70% from ultra-processed foods", shared Monsonego-Ornan. They found that the rodents experienced moderate damage to their bone density albeit there were fewer indications of cartilage buildup in their growth plates. "Our conclusion was that even in reduced amounts, the ultra-processed foods can have a definite negative impact on skeletal growth."  These findings are critical because children and adolescents consume these foods on a regular basis to the extent that 50 percent of American kids eat junk food each and every day. Monsonego-Ornan added. "when Carlos Monteiro, one of the world's leading experts on nutrition, said that there is no such thing as a healthy ultra-processed food, he was clearly right. Even if we reduce fats, carbs nitrates and other known harmful substances, these foods still possess their damaging attributes. Every part of the body is prone to this damage and certainly those systems that remain in the critical stages of development."   Results From The World's Largest Wellbeing Study Are In: Here's What We Know South Australian Health and Medical Research Institute, April 20, 2021 For decades, researchers have known that positive mental wellbeing seems to deliver significant improvements in physical health, development, and lifespan – which suggests looking after your mind and mental state is one of the most effective ways to care for the rest of your body as well. But what's the best way to actually promote personal mental wellbeing? In a new study led by scientists in Australia, researchers cast a wide net, analyzing data from almost 420 randomized trials employing different kinds of psychological interventions to help improve mental states of wellbeing. The results – a meta-analysis examining data from over 53,000 participants involved in hundreds of psychological experiments – is being billed as the world's largest study of its kind on wellbeing, giving perhaps the most comprehensive overview ever on how interventions can help towards a healthy mind and body. In the wake of the COVID-19 pandemic and the myriad hardships it has brought all over the world, new insights on how to successfully bolster mental states are in high demand. "During stressful and uncertain periods in our lives, pro-actively working on our mental health is crucial to help mitigate the risk of mental and physical illness," says mental health researcher Joep Van Agteren from the South Australian Health and Medical Research Institute (SAHMRI). "Our research suggests there are numerous psychological approaches people should experiment with to determine what works for them." In itself that might seem obvious, but as the researchers point out, up until now our awareness of psychological interventions' relative efficacy has been obstructed, given much research treats mental wellbeing and mental illness as different things, although they are overlapping concepts in some ways. Here, the researchers tried to take a broader view, looking at how a wide range of different types of psychological intervention can benefit mental wellbeing, irrespective of any particular theoretical foundation in psychology. Amongst the many forms of interventions included, two in particular stood out for their consistent associations with positive findings across trial cohorts: mindfulness-based interventions, and multi-component PPIs (positive psychological interventions), which package together a range of treatment methods and activities designed to cultivate positive feelings, behaviors, and thinking patterns. To a lesser extent, other interventions also appeared to deliver benefits, including acceptance and commitment therapy-based interventions, cognitive therapy, singular PPIs, and interventions focusing on reminiscence. While the effect sizes of these interventions are often moderate, the analysis here suggests they are linked with positive improvements in wellbeing in both clinical and non-clinical populations – but there's no quick fix, the researchers emphasize. "Just trying something once or twice isn't enough to have a measurable impact," says co-author Matthew Iasiello, a project coordinator at SAHMRI's Mental Health and Wellbeing program. "Regardless of what method people are trying out, they need to stick at it for weeks and months at a time for it to have a real effect." In their paper, the researchers make the same point in a different way. "Our moderator analysis indicated that improvement in mental wellbeing seems to be related to effort," the team writes. "While the review did not find a clear linear dose-response effect, with more exposure leading simply to better treatment outcomes, the results do indicate that more intense interventions seem to lead to more pronounced changes." Another insight by the researchers is that many kinds of psychological interventions can be done safely in volunteer groups or via online platforms, not requiring clinical appointments with professionals such as psychologists. With mental illness projected to become the largest contributor to disease by 2030, electing to look after yourself with these sorts of activities might not only benefit your own mental wellbeing and health – but the health of the health system too. "It is therefore potentially a cost-effective addition to current referral pathways and treatment methods," says clinical psychologist Michael Kyrios from Flinders University. "We need to take everyone's wellbeing seriously and ensure we're taking the necessary steps to improve mental and physical health so we can prevent future complications for ourselves and keep healthcare costs down." The findings are reported in Nature Human Behaviour.     The Stuff Beer Cans are Made from is Linked to Alzheimer's Disease Keele University (UK), April 15, 2021 There appears to be a troubling link between aluminum in the brain and the early signs of Alzheimer’s Disease, according to a new study. Researchers have known for years that aluminum has something to do with Alzheimer’s, but now Keele University scientists have discovered that the metal pops up at the same places in the brain as the tangles of tau protein that appear in the early stages of the disease, according to research published last month in the Journal of Alzheimer’s Disease Reports. The discovery suggests that it’s possible that aluminum could even play a role in forming those tangles and plaques — which precede the onset of Alzheimer’s — in the first place. “The presence of these tangles is associated with neuronal cell death, and observations of aluminum in these tangles may highlight a role for aluminum in their formation,” lead study author Matthew Bold said in a press release. That doesn’t mean that you need to ban aluminum cans from your home. Aluminum, perhaps introduced through food or other exposures, is commonly found in healthy brains, according to the Alzheimer’s Society, a dementia-focused charity based in London. But as people age, their kidneys may lose the ability to filter it out of the brain ­— potentially leading to the Alzheimer’s ties uncovered in the new study. “Aluminum accumulation has been associated with Alzheimer’s disease for nearly half a century,” Journal of Alzheimer’s Disease editor-in-chief George Perry said in the release, “but it is the meticulously specific studies of Drs. Mold and Exley that are defining the exact molecular interaction of aluminum and other multivalent metals that may be critical to formation of the pathology of Alzheimer’s disease.”     Drought-resistant cactus pear could become a sustainable food and fuel source, new research shows University of Nevada, April 16, 2021 Cactus pears could become a sustainable source of food and fuel in places in need of these two resources. Those are the findings of a recent study by researchers from the University of Nevada, Reno. Published in the journal GCB Bioenergy, the study covered five years of research. The group had set out to look at how successful different varieties of cactus pear would fare in warm, dry climates. They found that the prickly pear variety (Opuntia ficus-indica) produced the most fruit and used up 80 percent less water than other varieties to do so. With drought and heatwave events becoming more common worldwide, crops like corn and soybean may likely be heavily affected because they require more water than what might be available in the future. People will need to look for alternative crops that require less water, can tolerate droughts and still bear fruits. Cactus pears as sustainable food and fuel source Given current climate trends, the world is poised to get hotter and drier in the future. Therefore, plants that are drought-resistant and able to produce food with little water might soon become major sources of food. According to study co-author John Cushman, about 42 percent of all land on Earth is classified as arid or semi-arid. Therefore, there is enormous potential for planting cactuspears. Doing so has two main benefits. For starters, scientists can grow cactus pears in fields that are far too arid to be suitable for other crops. This increased production would put cactus pears on the map as food. Many cultures worldwide already eat the fruits from cactus pears and even the cactus pads themselves. However, cactus pears and other edible cactus varieties are far from being a major food and forage crop in the United States, let alone around the world. But that is a missed opportunity because cactus pear fruits can be used just like other fruits. They are especially great for making jams because they contain natural sugars. They can also be consumed fresh or pickled once the spines have been removed. They are also great for feeding livestock due to their high water content. The other benefit of utilizing arid fields for the cultivation of cactus pears is carbon sequestration. They capture and store carbon dioxide from the atmosphere, serving as a land-based carbon “sink.” They can also be harvested and used as raw materials for biofuels to replace fossil fuels. “That’s the benefit of this perennial crop,” explained Cushman. After you have harvested the fruits and pads for food, you will be left with a large amount of biomass that can be used for biofuel production, he said. (Related: Hemp: the versatile biofuel that could save America’s energy independence.) Cushman and his colleagues plan to continue researching cactus pears and their potential as sustainable fuel or foods. They plan to understand what it is about the genetic makeup of cactus pears that makes them so drought-resistant and use that information to make other crops more drought-resistant as well. Scientists have long been interested in the potential of cactus pears to serve as food and fuel. In 2015, a team of researchers from the United Kingdom suggested that water-efficient plants like cacti could be the key to providing sustainable bioenergy for the future. Plants like cacti carry out photosynthesis through a crassulacean acid metabolism (CAM) system. They grow on arid and semi-arid land with low or unpredictable rainfall, which can make conventional farming difficult. Arid and semi-arid lands are unproductive. But they can be put to good use by filling them with cacti and many other CAM plants that can capture and store carbon efficiently. The researchers said CAM plants like prickly pear could make a huge contribution to sustainable biogas production this way.   Yeast in kefir drink combats disease-causing bacteria Ben-Gurion University (Israel), April 17, 2021 People may have been producing and drinking kefir, a fermented milk drink that originated in Tibet and the North Caucasus, for thousands of years. People can make the sour, slightly effervescent brew by infusing milk with kefir grains, which are a starchy matrix containing a symbiotic community of lactic acid bacteria, acetic bacteria, and yeasts.  The drink has many reputed health benefits, which include lowering cholesterol, reducing inflammation, and exerting an antioxidant effect.  In common with other probiotics, kefir also has antimicrobial properties. However, scientists were unsure exactly how it inhibits the growth of disease-causing bacteria. Researchers at Ben-Gurion University of the Negev (BGU) in Be’er Sheva, Israel, have now discovered that a type of yeast in kefir called Kluyveromyces marxianus secretes a molecule that disrupts bacterial communication. Scientists already knew that plants and algae produce this substance, called tryptophol acetate, but this is the first time that they have found a yeast that makes it. They discovered that tryptophol acetate interferes with “quorum sensing” — a form of microbial communication — in several disease-causing bacteria.  In quorum sensingTrusted Source, bacteria release signaling molecules into their surroundings. When the molecules reach a particular concentration, they trigger changes in the expression of genes in bacteria of the same species. These changes allow disease-causing bacteria to coordinate their activity according to their numbers. This coordination is necessary for some bacteria to defend themselves or attack their hosts.  In some cases, when they reach a certain density, the microbes may come together to form a slimy, protective coating, or “biofilm,” on a surface.  Disease-causing bacteria In lab cultures, the researchers found that tryptophol acetate had an inhibitory effect over quorum sensing in several disease-causing bacteria, including some Gram-negativeTrusted Source bacteria. Some of the tested species were: Pseudomonas aeruginosa, which causes pneumonia when it infects the lungs.  S. enterica, which is responsible for food poisoning.  Staphylococcus aureus, which can trigger sepsis, among other life threatening infections. V. cholerae, which causes cholera. The research, which Ph.D. student Orit Malka led, appears in the journal BMC Microbiome. “These results are notable, since this is the first demonstration that virulence of human pathogenic bacteria can be mitigated by molecules secreted in probiotic milk products, such as yogurt or kefir,” says senior author Prof. Raz Jelinek. The scientists focused in particular on the effect of tryptophol acetate on V. cholerae. They found that the substance blocked quorum sensing in this bacteria and reduced its virulence. It did this by changing the expression of bacterial genes that control quorum sensing. The researchers write that this kind of interference in bacterial communication may be commonplace in complex environments where many different microorganisms live together, such as in probiotic food or the human gut.   Living near pesticide-treated farms raises risk of childhood brain tumors Cedars-Sinai Medical Center, April 15, 2021 Pregnant women living within 2.5 miles of agricultural lands treated with pesticides have a greater risk of their children developing central nervous system (CNS) tumors, according to a recent study. Published on Wednesday, March 31, in the Environmental Research journal, the study also revealed that the pregnant women did not have to be working in agriculture or in close contact with pesticides for health-harming exposures to occur. Study co-author Christina Lombardi, a public health researcher at Cedars-Sinai Medical Center in Los Angeles, said there are large numbers of pregnant women and children living close to pesticide-treated farmlands. Both mothers and children could experience adverse health effects from their proximity to those farmlands. The study is not the first to show that pesticide use poses a threat to pregnant women and their children. But it is unique in that it showed the specific pesticides linked to the development of different kinds of CNS tumors. Maternal exposure to pesticides linked to childhood tumors Experts have examined pesticide exposures as risk factors for the development of childhood brain cancers. But they have yet to assess the risk of developing childhood brain cancers from exposure to specific pesticides. (Related: California is going after another dangerous pesticide: Chlorpyrifos has been linked to brain damage.) To that end, Lombardi and her colleagues from the University of California, Los Angeles made use of the California Cancer Registry to identify cases of childhood CNS tumors in children below six years old. Overall, the researchers found 667 cases of CNS tumors in children below six. They matched each one with 20 controls to increase the statistical power of their findings. They then checked pesticide application records from the California Department of Pesticide Regulation‘s (CDPR) Pesticide Use Reporting (PUR) system to determine whether chemicals classified as possible carcinogens were used within 2.5 miles of the mothers’ homes at the time of the children’s births. Results showed that maternal exposure to certain pesticides heightened the risk of certain childhood CNS tumors by 2.5 times, even if the mother was not a farmworker. Pesticides found to increase the risk of childhood CNS tumors include thiophanate- and kresoxim-methyl, chlorothalonil, bromacil, triforine, propiconazole, dimethoate and linuron. Co-author Julia Heck said their findings are more precise than those of previous studies on pesticide exposure, which usually grouped pesticide use into broad categories based on type, such as herbicides or insecticides. Heck added that their results suggest that exposure to specific pesticides may best explain the results of earlier studies that reported a link between broader pesticide types and CNS tumors. Due to the risks that pesticide exposure poses on pregnant women and children, the researchers called for policy interventions to reduce pesticide exposure among people living near farms. “The simplest way to mitigate these risks is by reductions in exposure to pesticides,” said co-author Myles Cockburn. This can be done by restricting harmful practices like aerial spraying and air blast. Exposure to pesticides may also be reduced by promoting farming methods that limit reliance on pesticides.

Dr Cathy Foley is a physicist and commenced her term as Australia's ninth chief scientist in January 2021. Before that she had a long and distinguished career at CSIRO, where she was appointed chief scientist in August 2018 – only the second woman in that role.Over the course of her career, she has made significant contributions to the understanding of semiconductors and high-temperature superconductors. Her work led to the development of field-deployable superconducting devices that locate valuable mineral deposits by detecting minute magnetic fields (ten million times weaker than the Earth's field).Dr Vikram Sharma is a quantum physicist and the founder and CEO of Canberra-based QuintessenceLabs, which is a world leader in the quantum cybersecurity industry. Vikram is a dual MSc holder – in computer science (from ANU), and management (from Stanford University, California). His doctorate in quantum physics was also awarded by ANU.Dr Johan Verjans is a cardiologist who combines clinical and research work. He's deputy director, Medical Machine Learning, at the Australian Institute for Machine Learning; a senior lecturer at the University of Adelaide attached to South Australian Health and Medical Research Institute; an associate investigator at Adelaide Uni's Centre for Nanoscale Biophotonics; and a consultant cardiologist at Royal Adelaide Hospital.Our guests join moderator Tory Shepherd, an Adelaide-based journalist and broadcaster, to discuss what AI is, its certain prevalence in our future, the variety of real-world applications for which it's already used, and future applications, both already in development and as yet only imaginedFind the science of everything at cosmosmagazine.com

In this episode I discuss a paper published in 2017 in BMJ Open, entitled “Sing Your Lungs Out—a community singing group for chronic obstructive pulmonary disease: a 1-year pilot study”. The first author of the paper is Dr. Amanda McNaughton from the Medical Research Institute of New Zealand. Please see https://lungfit.med.ubc.ca to get copies of the open access papers.  As always, I welcome your feedback about the show or ideas for future episodes. You can contact me via the comments section on the LungFIT website. If you listen to the LungFIT podcast on iTunes, please take a moment to review the show.

Dr. Yasmine Probst is a Senior Lecturer at the University of Wollongong, and a Research Fellow with the Illawarra Health and Medical Research Institute. She is recognized as an Advanced Accredited Practicing Dietitian with the Dietitians Association of Australia, and a Fellow of the Australasian College of Health Informatics. She was recently featured in the very interesting documentary, Vitamania, in which the discussion around whether we should be taking vitamin supplements, was brought to the table. Yasmine and I discussed: What synthetic vitamins are made from What are the different types of vitamins? Living with MS Do we actually need supplements? The connection between food & disease Should our canine companions take vitamins? Is there a "best diet" for humans? How many vitamins we actually need And much more... Yasmine's Twitter My Take: Question everything, but don't get yourself in a frenzy. Just be aware of what you put into your body. Food companies have worked tirelessly to market their products as "natural" or "healthy", but often their actual ingredient list, tells a different story. Do your research. Support the Podcast

In this episode of Bulletproof Radio, I’m joined by Australian researcher Leonie Heilbronn, Ph.D.. Her fasting research looks at the biological pathways that support reducing the risk of chronic diseases.Leonie leads the Obesity and Metabolism group based within the Lifelong Health Theme at South Australian Health and Medical Research Institute at Adelaide University in Adelaide, Australia. Today, I have her on to talk about her studies on fasting, many of which show more specific results than what we’ve seen in this field before. She looks at intermittent fasting, time restricted eating, calorie restriction and more. In a particular study on women, Leoni says, “We did see that the intermittent fasting group lost a little bit more weight than the caloric restriction group, and they had better improvements in their health.” There were other positive results like reductions in diabetes and cardiovascular risk markers. Fasting isn’t one-size-fits-all, so I asked Leonie a lot of questions about her research, such as:How does the food you eat during intermittent fasting affect the fast itself? What food works for some people and not others and how does that influence the effectiveness of your fast? How do intermittent fasting and caloric restriction compare? When should you eat your daily protein and carbs? Should you consume black coffee during your fast? How does time-restrictive eating affect your lifespan?How do people respond in fasting studies? “For some people, it takes them a little while to get used to fasting and then some people just maybe never get used to it,” she says. How do people respond in time restrictive eating studies? “I think time restrictive eating is great because you don’t really have to change everything that you’re eating and you’re still going to have some really good effects,” she says. “But I think if you started to have bad behaviors because of time pressure, then you’re not going to see the improvement that we’d hope to see.”Leonie breaks down her research in in simple terms, so no matter what your familiarity with fasting might be, you’ll find a fascinating entry point. Enjoy! And get more resources at https://blog.daveasprey.com/category/podcasts/WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Replenish Electrolytes: https://drinklmnt.com/dave; claim your free Sample Pack with $5 shippingAnti-Aging Solution: https://spermidinelife.us/dave; use code DAVE25 for 25% off your first month’s orderDigestive Health: https://globalhealing.com/dave; use code DAVE15 to get 15% off all productsDAVE ASPREY’S NEW BOOK LAUNCHES JANUARY 19, 2021!Pre-order “Fast This Way: Burn Fat, Heal Inflammation, and Become the High-Performing Human You Were Meant to Be” and you’ll receive special product offers and enroll in Dave Asprey’s first ever Fasting Challenge: https://fastthisway.com

In this episode of Bulletproof Radio, I’m joined by Australian researcher Leonie Heilbronn, Ph.D.. Her fasting research looks at the biological pathways that support reducing the risk of chronic diseases.Leonie leads the Obesity and Metabolism group based within the Lifelong Health Theme at South Australian Health and Medical Research Institute at Adelaide University in Adelaide, Australia. Today, I have her on to talk about her studies on fasting, many of which show more specific results than what we’ve seen in this field before. She looks at intermittent fasting, time restricted eating, calorie restriction and more. In a particular study on women, Leoni says, “We did see that the intermittent fasting group lost a little bit more weight than the caloric restriction group, and they had better improvements in their health.” There were other positive results like reductions in diabetes and cardiovascular risk markers. Fasting isn’t one-size-fits-all, so I asked Leonie a lot of questions about her research, such as:How does the food you eat during intermittent fasting affect the fast itself? What food works for some people and not others and how does that influence the effectiveness of your fast? How do intermittent fasting and caloric restriction compare? When should you eat your daily protein and carbs? Should you consume black coffee during your fast? How does time-restrictive eating affect your lifespan?How do people respond in fasting studies? “For some people, it takes them a little while to get used to fasting and then some people just maybe never get used to it,” she says. How do people respond in time restrictive eating studies? “I think time restrictive eating is great because you don’t really have to change everything that you’re eating and you’re still going to have some really good effects,” she says. “But I think if you started to have bad behaviors because of time pressure, then you’re not going to see the improvement that we’d hope to see.”Leonie breaks down her research in in simple terms, so no matter what your familiarity with fasting might be, you’ll find a fascinating entry point. Enjoy! And get more resources at https://blog.daveasprey.com/category/podcasts/WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Replenish Electrolytes: https://drinklmnt.com/dave; claim your free Sample Pack with $5 shippingAnti-Aging Solution: https://spermidinelife.us/dave; use code DAVE25 for 25% off your first month’s orderDigestive Health: https://globalhealing.com/dave; use code DAVE15 to get 15% off all productsDAVE ASPREY’S NEW BOOK LAUNCHES JANUARY 19, 2021!Pre-order “Fast This Way: Burn Fat, Heal Inflammation, and Become the High-Performing Human You Were Meant to Be” and you’ll receive special product offers and enroll in Dave Asprey’s first ever Fasting Challenge: https://fastthisway.com

Research led by University of South Australia PhD candidate Katharine McBride has found what makes the heart strong for Aboriginal and Torres Strait Islander women. Did you know, the life expectancy of Aboriginal women is 75.6 years, compared to 83.4 years for non-Aboriginal women?According to McBride’s paper, ‘Good Heart: Telling Stories of Cardiovascular Protective and Risk Factors for Aboriginal Women’, the current approach to heart health is not working because the model of care fails to meet Aboriginal women’s cultural needs.Cardiovascular disease is the leading cause of death for Aboriginal women and McBride's study explains what changes are needed to meet the 2031 Closing the Gap target.Anna Dowling, a Yamatji Badimia woman and Research Assistant at South Australian Health and Medical Research Institute, is a member of the advisory group who worked on the study. The advisory group agreed that Aboriginal women’s voices need to be prioritised to understand what protects the heart and puts it at risk.

Episode 4 features Bill Bauer, the Education and Diversity Director at Hauptman Woodward Medical Research Institute located in Buffalo, NY. Bill talks about advice for networking and starting a data analysis career in the biomedical field.   Links shared during interview:Alaina Levine Networking Seminar - Networking for Nerds: Create Your Dream Career-Alaina G. Levine-Keynote Speaker National Research mentoring network -https://nrmnet.net/#undergradPopup The Coder School - https://www.thecoderschool.com/locations/buffalo/ Hauptman Woodward Internships - https://hwi.buffalo.edu/education/  Interested in a career in data science? Visit https://dataanalytics.buffalostate.edu/ to learn more.

Paediatric research dietician from the South Australian Health and Medical Research Institute, Dr Merryn Netting, explains. See omnystudio.com/policies/listener for privacy information.

Today's podcast interview is a little different from the first two. Although, like the others, this interview was done for my last documentary project, My Year of Living Mindfully, it isn't with someone who's specifically a mindfulness researcher.   It's with a scientist at the forefront of understanding the connection between our mind, body and health. If you've seen my first documentary, The Connection, you'll know that is a topic I'm really committed to understanding more.    I did this interview while I was still setting-up my ridiculously elaborate, hare brained experiment to see what would happen to my health and wellbeing if I meditated every day for a year.    It meant having to take a plane from my home in Sydney, Australia to the other side of the world, then taking another plane and yet another plane. Eventually I arrived at the Global Wellness Summit in Palm Beach, Florida, where Professor Elissa Epel, the Director of the Aging, Metabolism and Emotion Center at University of California San Francisco Medical School, was giving a key note speech about her research investigating how chronic stress can impact our health and biological ageing, and how activities like mindfulness may slow or even reverse those effects.   I knew the journey would be worth it because although Elissa and I hadn't met before, she had already made a big impression on how my own lifestyle was influencing my health. Among many other things, she co-authored a best-selling book called The Telomere Effect, with the Nobel prize winning molecular biologist, Elizabeth Blackburn.   Elissa's influential research demonstrating that mind-body activities like mindfulness training can slow down the rate at which our cells age, was the reason I'd enlisted the help of Associate Professor, Hilda Picket, from Sydney University's Children's Medical Research Institute. Hilda had already measured my telomeres from two control blood samples taken before I began meditating daily. I really wanted to know whether doing something with my mind could have downstream effects throughout my body, and impact my physical health.  

Scott and Adam are joined by Dr Katrina Green of Molecular Horizons and Senior Lecturer for the Illawara Health and Medical Research Institute, University of Woolongong. Scott and Adam learn about cannabinoids, terpenes and the endocannabinoid system from the bubbly yet sophisticated neuroscientist. Dr Green dispels some myths and provides some wonderful insights into the scientific interactions of cannabis and the brain.

In health research we often hear, and pay lip service to the term ‘patient centred‘. Many of us would probably be hard pressed to devise entirely patient centred studies. "Take Charge’ is an impressive, novel, community-based self-directed rehabilitation intervention that helps a person with stroke to take charge of their own recovery.  In a previous randomised controlled trial, a single Take Charge session improved independence and health-related quality of life 12 months following stroke in Māori and Pacific New Zealanders.  This current study confirms that Take Charge; a low cost, person-centred, self-directed rehabilitation intervention after stroke – improved health-related quality of life and independence. Carmen Lahiff-Jenkins Managing Editor of the International Journal of Stroke and spoke to Dr Harry McNaughton who conducted the study from the Medical Research Institute of New Zealand in the Stroke/Rehabilitation Research Department at Wellington Hospital. Dr McNaughton and team tested the same intervention in three doses (zero, one or two sessions) in a larger study and in a broader non-Māori and non-Pacific population with stroke. We spoke to him about how this trial came about and how these really astounding results could change the way we look at some rehabilitation interventions.  This podcast is sponsored by the World Stroke Organisation  

I interviewed Darryl Harkness, the CEO of the Ingham Institute for Applied Medical Research to find out why and how the Ingham Institute was created in this competitive environment. In October 2012, the Ingham Institute came to life in Sydney's South West with massive generous support from Mr Bob Ingham AO and his family. The Ingham Institute is now one of the 55 Medical Research Institutes in Australia.A major goal of the Ingham Institute is to perform world-class translational research that benefits the local community. I asked Darryl how he defines and measures world-class research, how the institute attracts top researchers and how research can solve local health challenges. Interestingly, the Ingham Institute is also very open to the public and invites members of the community to engage with basic researchers and clinicians, ask questions and directly help shape the research. The Institute also brings local business and government leaders and donors to support and connect with the research and make a local impact. Finally Darryl shares his vision for the future of the Ingham Institute and the multi-billion dollar redevelopment plan to enable Liverpool to become a competitive and innovative health precinct. In the next few years, we will see major capabilities and innovation in Liverpool not only in medical research, but also clinical trials, commercialisation and robotics…Listen on Apple Podcasts or on Spotify! See acast.com/privacy for privacy and opt-out information.

Vol 211, Issue 9: 4 November 2019. Dr Jody Moller is a Research Fellow at the University of Wollongong and the Illawarra Health and Medical Research Institute. She talks about pill-testing and its' use as a harm reduction strategy. With MJA news and online editor, Cate Swannell.

Dr Phil Worley, Chair for the RACS South Australia State Committee, examines the current and future initiatives in South Australia. In recent times, the state has benefited from major medical developments, including the Royal Adelaide Hospital and the South Australian Health and Medical Research Institute. In early September, Port Lincoln will host the SA, NT and WA ASM; this year's theme is 'Robots in Surgery – Tsunami or just the next wave?'  The SA, NT and WA Annual Scientific Meeting Dates: 5-7 September Location: Port Lincoln Hotel Details: https://www.surgeons.org/conferences-events/college-calendar/2019-sa-nt-wa-annual-scientific-meeting Contact: 08 8239 1000 or email college.sa@surgeons.org 

In this episode of Take as Directed, J. Stephen Morrison speaks with Dr. Trevor Mundel, President of the Global Health Division at the Bill & Melinda Gates Foundation. They discuss the arc of Dr. Mundel’s personal career and his remarkable tenure at the Gates Foundation, including the creation of the Medical Research Institute; the launch of CHAMPS, the Child Health and Mortality Prevention Service; and the establishment of CEPI, the Coalition for Epidemic Preparedness Innovations. In closing, they discuss the issues that give him the greatest concern, and the reasons he is hopeful looking to the future.

In this episode of Take as Directed, J. Stephen Morrison speaks with Dr. Trevor Mundel, President of the Global Health Division at the Bill & Melinda Gates Foundation. They discuss the arc of Dr. Mundel’s personal career and his remarkable tenure at the Gates Foundation, including the creation of the Medical Research Institute; the launch of CHAMPS, the Child Health and Mortality Prevention Service; and the establishment of CEPI, the Coalition for Epidemic Preparedness Innovations. In closing, they discuss the issues that give him the greatest concern, and the reasons he is hopeful looking to the future.

Up until 2 weeks ago 'burn-out' from work was considered to be just your poor time management or lifestyle issues - but not anymore. The World health Organisation has decided to list it as an occupational phenomena caused by chronic stress and something we need to address. Today we find out how to recognise it, how to deal with it and how to communicate it to your boss. CREDITS Host/Producer: Claire Murphy Executive Producer: Elle Beattie Audio Producer: Ian Camilleri Thanks to our special guests Burnout Coach LaTanya N. Riggs and Michael Musker from the South Australian Health and Medical Research Institute. The Quicky is the easiest and most enjoyable way to get across the news every day. And it's delivered straight to your ears in a daily podcast so you can listen whenever you want, wherever you are...at the gym, on the train, in the playground or at night while you're making dinner. The Quicky. Getting you up to speed. Daily. Want The Quicky in your ears every day?  Subscribe at mamamia.com.au/the-quicky or in your favourite podcast app. Love the show? Send us an email thequicky@mamamia.com.au or call the podphone 02 8999 9386. See omnystudio.com/listener for privacy information.

The 2019 season of the CGA-IGC podcast series, Expert Approach to Hereditary Gastrointestinal Cancers, will focus on the management of extra-colonic features of APC-Associated conditions. In the second episode, Dr. Daniel Worthley, an expert in hereditary cancer syndromes from the South Australian Health and Medical Research Institute, tells the tale of how Gastric Adenocarcinoma and Proximal Polyposis of the Stomach (GAPPS) was first recognized and characterized. GAPPS is caused by a mutation in the promotor region of the APC gene and is inherited in an autosomal dominant fashion. This condition is associated with a significantly increased risk of gastric cancer, but unlike FAP, GAPPS is not associated with tumors in the colon or small bowel. Dr. Worthley reviews the characteristics of this rare condition and current approach to management. Note: This episode was recorded on April 23, 2019, and reflects expert opinion at the time of recording. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.

So 3 weeks in a leg brace ... If you know me you have probably heard me say, "you would have to strap me to a bed and sedate me in order to stop me walking and training every day." What has come up in the last few weeks is all the fear underneath the constant moving that I tend to do. Sure I meditate (at 4am before I get up and start moving), I contemplate (while I hike or swim), I sit down to eat (most of the time). But I have know for a very long time that I have a fear of sitting still. I had a workshop at SAHMRI (South Australian Health and Medical Research Institute) for two days last week. I enrolled last year and every time I thought about it, or saw it in the diary, I felt that mix of fear and a desire to pull out that is all too familiar. Even after hurting my leg and being put in a leg brace, I didn't want to do it. If there is something that involves sitting down for hours on end ... I really do not want to do it. Long lunches. Full day workshops. Lectures. Long drives, long flights, basically anything that requires more than 30 minutes sitting down. If I have spare time I clean the windows, vacuum, go for a run, walk to the shops. take the kids and dog to the park, run around finding jobs to do ... anything to avoid sitting down. Why? What is with this fear? It is the same fear that you may feel about sitting still, or not watching TV every night, or not having your phone to check when you sit at the bar waiting to meet your friend. Or maybe it’s the fear that is underneath your snacking every time you have spare time, or calling your mum, or messaging friends, checking email, checking your apps, news feed ... What do you do to check out? To avoid being alone with yourself? What is beneath that fear? For me in the past I would eat or drink wine. That was my go to that caused the most damage in my life. But for my entire adult life movement has been the big one. The one I refuse to let go off. The one that is 'healthy' and 'good for you' and a 'good addiction to have'. It is also a great way to avoid being alone with yourself, with your true self, with all the stuff underneath. So ... that’s been my week. Being faced with all the stuff underneath. Learning to love that stuff, learning to question that stuff, to test if it is true, and to let it go if it isn't. This week’s podcast is about the stuff and about being honest with yourself - recorded with so much love for you all. If you are ready to put all your podcast listening into action you have to check out my coaching program. Your Life Designed a monthly coaching program for high functioning people who want to invest in their personal development. This program brings together the latest research on human potential and high performance. It teaches you actionable strategies to implement in your life. It takes ideas, knowledge and learning to the next level, so that you get the results you want in your life. For as little as $25.00AUD per week this program gives you the skills to consistently perform at a high level in all areas of your life with a sense of joy, confidence and fulfilment. Your Life Designed. Extraordinary people. Extraordinary lives. Learn more and subscribe today at https://www.lauracarrocci.com/coaching Connect with Laura and find out more - https://lauracarrocci.com Send Laura an email - laura@lauracarrocci.com Podcast produced by Apiro - http://apiropodcasts.com

What it is like when a much loved and respected leader in your Intensive Care suddenly dies? And do you view the people you work with in your ICU as an extended family?   Paul Young, an Intensivist from New Zealand, discusses his perspectives on these questions, amongst many other valuable insights, in this important and moving interview. Paul Young is an intensive care specialist at Wellington Hospital in New Zealand where he is the co-clinical leader at Wellington ICU. He is also medical director of Wakefield Hospital ICU, Deputy Director at the Medical Research Institute of New Zealand, and holds a Clinical Practitioner Research Fellowship from the Health Research Council of New Zealand. Paul's predominant non-clinical interest is in ICU research. Since starting work as an intensive care specialist in 2010 he has published more than 120 papers in peer-reviewed journals including five papers in the New England Journal of Medicine, two in JAMA, and one in the Lancet. His involvement in clinical research has been instrumental in the development of his belief that intensive care is fundamentally about keeping people alive for long enough for them to recover whilst meddling as little as possible. In his leadership roles he encourages people to find joy in their work and to be nice to each other yet he constantly battles with his own tendency towards sarcasm. In late 2018, Dr Peter Hicks, the Clinical Lead at Wellington Hospital died suddenly. Peter was an excellent intensivist, a wonderful leader, and a friend to many in the Australian and New Zealand ICU community. His death is sad for all who knew him and most notably his family and colleagues. Paul speaks in this interview about the legacy Peter left behind, how Peter particularly guided Paul in his career and how the Wellington ICU is moving on after Peter’s untimely death. In this conversation, Paul also discusses: Why he became an intensivist The cultural differences between Australia and New Zealand Telling the truth about his thoughts on the patient’s likely outcome Worrying - and when it's useful and not useful The specifics of his ward round What it’s like to have consultants changing daily in his ICU The start to his research career Some insights on designing clinical trials to answer important questions Why “negative studies” are so important to advance clinical practice (using the TARGET study as an example) How he keeps up with the literature including with Twitter His efforts to be more kind and to get on with people The effects of running on his general wellbeing A challenge for other units to try a “day about” clinical roster Paul is clever, incisive, and is delightfully able to simplify many concepts about intensive care practice and research. Please enjoy listening to Dr Paul Young.   Andrew Davies   --------------------   About the Mastering Intensive Care podcast: The podcast is aimed to inspire and empower you to bring your best self to the intensive care unit, through conversations with thought-provoking guests. I hope you’ll glean insights to help you improve as a healthcare professional and as a human being so you can make a truly valuable contribution to your patient’s lives.   --------------------   Links to people, organisations and other resources mentioned: Paul Young on Twitter: @dogICUma Wellington ICU website Tribute to Peter Hicks written by David Pilcher ANZICS CTG (Australian and New Zealand Intensive Care Society Clinical Trials Group) Rinaldo Bellomo Critical Care Reviews Rob MacSweeney Wellington ICU Journal Club on Twitter: @WellingtonICU TARGET study Tweetorial on the TARGET study by Paul Young Rana Awdish on Twitter: @RanaAwdish Book "In Shock" (by Rana Awdish) Mastering Intensive Care podcast: Episode 3 with Rinaldo Bellomo Mastering Intensive Care podcast: Episode 19 with Alex Psirides Mastering Intensive Care podcast: Episode 20 with Jack Iwashyna Mastering Intensive Care podcast: Episode 23 - The Best of 2017 (Part 1) Mastering Intensive Care podcast: Episode 24 - The Best of 2017 (Part 2) Mastering Intensive Care podcast: Episode 39 - The Best of 2018 Mastering Intensive Care podcast – episode 41 with Rana Awdish Mastering Intensive Care podcast Mastering Intensive Care page on Facebook Mastering Intensive Care at Life In The Fast Lane Andrew Davies on Twitter: @andrewdavies66 Andrew Davies on Instagram: @andrewdavies66 Email Andrew Davies: andrew@masteringintensivecare.com  

Omega-3 fats are the subject of more than two dozen Cochrane Reviews for conditions including cardiovascular health, dementia and gastrointestinal problems. In November 2018, the review on the effects on preterm birth when these are taken by pregnant women was updated. The review was led by Associate Professor Philippa Middleton and Professor Maria Makrides, from the Healthy Mothers Babies and Children theme at the South Australian Health and Medical Research Institute. Professor Makrides tells us about the latest evidence.

Omega-3 fats are the subject of more than two dozen Cochrane Reviews for conditions including cardiovascular health, dementia and gastrointestinal problems. In November 2018, the review on the effects on preterm birth when these are taken by pregnant women was updated. The review was led by Associate Professor Philippa Middleton and Professor Maria Makrides, from the Healthy Mothers Babies and Children theme at the South Australian Health and Medical Research Institute. Professor Makrides tells us about the latest evidence.

Omega-3 fats are the subject of more than two dozen Cochrane Reviews for conditions including cardiovascular health, dementia and gastrointestinal problems. In November 2018, the review on the effects on preterm birth when these are taken by pregnant women was updated. The review was led by Associate Professor Philippa Middleton and Professor Maria Makrides, from the Healthy Mothers Babies and Children theme at the South Australian Health and Medical Research Institute. Professor Makrides tells us about the latest evidence.

During National Science Week, thousands of events are held around the country to shine a light on the work of our researchers. Dr Adrian Elliott from the South Australian Health & Medical Research Institute and University of Adelaide discusses his latest study which aims to understand more about athletes’ hearts and how they adapt over time.

PharmaPills - Pillole dal farmaceutico: Novità, Curiosità e Lavoro dal mondo del farmaceutico. A cura di Stefano LagravineseIn questa puntata parliamo di:Aziende: IQVIA, Allergan, Johnson&Johnson, Grünenthal, Fidia Pharma, Sooft, Recordati, Natural Point, Medical Research Institute, AIFA, AstraZeneca, Eli Lilly, PRA Health Sciences, PSI CRO, PPD.Persone: Ari Bousbib (IQVIA), Brenton Saunders (Allergan), Alex Gorski (Johnson&Johnson), Massimo Scaccabarozzi (Farmindustria), Giorgio Bruno (AFI), Francesco De Santis (Italfarmaco), Enrique Häusermann (Assogenerici), Francesco Saverio Mennini (Università di Roma Tor Vergata), Aldo Sterpone (Grünenthal), Mark Fladrich (Grünenthal), Carlo Pizzoccaro (Fidia Pharma), Andrea Recordati (Recordati), Bill Gates (Bill Gates Foundation), Emma Haapaniemi (Karolinska Institute).Nuove terapie: lanabecestat.Patologie: Alzheimer.Lavoro: Regulatory Affairs Associate, CRA II, CRA.Ogni mercoledì alle h 12.00 su Spreaker.com e iTunes.Seguici su: www.telegram.me/pharmapillswww.facebook.com/pharmapills/

PharmaPills - Pillole dal farmaceutico: Novità, Curiosità e Lavoro dal mondo del farmaceutico. A cura di Stefano LagravineseIn questa puntata parliamo di:Aziende: IQVIA, Allergan, Johnson&Johnson, Grünenthal, Fidia Pharma, Sooft, Recordati, Natural Point, Medical Research Institute, AIFA, AstraZeneca, Eli Lilly, PRA Health Sciences, PSI CRO, PPD.Persone: Ari Bousbib (IQVIA), Brenton Saunders (Allergan), Alex Gorski (Johnson&Johnson), Massimo Scaccabarozzi (Farmindustria), Giorgio Bruno (AFI), Francesco De Santis (Italfarmaco), Enrique Häusermann (Assogenerici), Francesco Saverio Mennini (Università di Roma Tor Vergata), Aldo Sterpone (Grünenthal), Mark Fladrich (Grünenthal), Carlo Pizzoccaro (Fidia Pharma), Andrea Recordati (Recordati), Bill Gates (Bill Gates Foundation), Emma Haapaniemi (Karolinska Institute).Nuove terapie: lanabecestat.Patologie: Alzheimer.Lavoro: Regulatory Affairs Associate, CRA II, CRA.Ogni mercoledì alle h 12.00 su Spreaker.com e iTunes.Seguici su: www.telegram.me/pharmapillswww.facebook.com/pharmapills/

Jane caught up with two members of the writing group for the recently updated Therapeutic Guidelines: Cardiovascular. Confusingly, they are also called Jane and Dan! Jane O'Connor is an Editor at Therapeutic Guidelines and Dr Daniel Scherer is a Cardiologist and PhD Candidate at the South Australian Health and Medical Research Institute.

De-stigmatising mental health and supporting stronger familiesThe celebrations and challenges of raising children can be a rich, diverse journey for all of us. Even when we are feeling mentally strong, there are moments when life, relationships and parenting is a bumpy road. For 1 in 10 people, living with a personality disorder and parenting can add a tremendous strain to our family experiences and bonds. An umbrella term for more commonly referred to conditions like borderline, narcissism, obsessive compulsive, avoidant and schizotypal, personality disorder can cause significant distress and impairment for the person and families. In this episode, I'll be traversing the mindscape of personality disorders, wellness, parenting and relationships with Dr Michelle Townsend; a Research Fellow at the Illawarra Health and Medical Research Institute and Project Air Strategy for Personality Disorders at the University of Wollongong. Shining a light on a rarely recognised area of parenting, this show will help de-myth the stigma around mental health, whilst providing strategies and support for those living with a personality disorder.24 Hour support for mental illness is available via Lifeline on 13 11 14.Presenter and producer: Sean TonnetCopyright PBB Media 2018, Sean TonnetFirst aired on 99.9 BayFM Byron Bay on Monday 19 March 2018Link to Project Air and Dr Michelle Townsend: www.projectairstrategy.org

De-stigmatising mental health and supporting stronger familiesThe celebrations and challenges of raising children can be a rich, diverse journey for all of us. Even when we are feeling mentally strong, there are moments when life, relationships and parenting is a bumpy road. For 1 in 10 people, living with a personality disorder and parenting can add a tremendous strain to our family experiences and bonds. An umbrella term for more commonly referred to conditions like borderline, narcissism, obsessive compulsive, avoidant and schizotypal, personality disorder can cause significant distress and impairment for the person and families. In this episode, I'll be traversing the mindscape of personality disorders, wellness, parenting and relationships with Dr Michelle Townsend; a Research Fellow at the Illawarra Health and Medical Research Institute and Project Air Strategy for Personality Disorders at the University of Wollongong. Shining a light on a rarely recognised area of parenting, this show will help de-myth the stigma around mental health, whilst providing strategies and support for those living with a personality disorder.24 Hour support for mental illness is available via Lifeline on 13 11 14.Presenter and producer: Sean TonnetCopyright PBB Media 2018, Sean TonnetFirst aired on 99.9 BayFM Byron Bay on Monday 19 March 2018Link to Project Air and Dr Michelle Townsend: www.projectairstrategy.org

ACT, FAIL, ADAPT AND EVOLVE. Raymond Spencer is a beacon of knowledge and wisdom for Australian entrepreneurs. Having begun his career in the non-for-profit- sector his entry into the business world came with a mountain of life experience behind him. And it showed. Raymond is currently, Chairperson of the South Australian Economic Development Board and South Australian Heath and Medical Research Institute; Chairperson, CEO, Executive and/or founder of numerous public companies; and owner/founder of many private companies from wineries to tech start-ups to venture capitalists. Raymond’s essay question was: “A worldwide entrepreneur, you left South Australia when you were 18 years of age not to return for some 35 years. What’s your view of South Australia’s potential on a global scale? And what life lessons learnt in the world of business are a must to be implemented by our public leaders in pursuit of developing the potential of the state you so love?” Raymond joined me in conversations ranging from 'lessons in vulnerability' learned in Indian villages through to the 'necessity of failing' for a successful business. This was a information filled episode. Enjoy the Show.   Show Notes 00.00 : 02.32 – Introductions and Adverts 02.33 : 03.35 - WWO INtro 03.36 : 04.48 - Welcome and Banter  04.49 : 11.56 - Planning, Visions & Decisions 11.57 : 13.08 - Control the Contradictions 13.09 : 18.12 - The Short Vision epidemic 18.13 : 21.40 - Evolve, Adapt and Investing Talent & Time 21.41 : 27.55 - Transfer Your Core Competencies 27.56 : 32.53 - Raw Lessons in Vulnerability 32.54 : 36.16 - Lead and Encourage Failure 36.17 : 41.25 - Happiness from the Fundamentals of Life 41.26 : 45.46 - Enjoy what you do in Life 45.47 : 50.15 - Acknowledge and Celebrate 50.16 : 59.35 - Your Evolution is in Your DNA 59.36 : 1.06.05 - Owning a Winery, from technology to vineyards 1.06.06 : 1.15.35 - Inspired by our Opportunity with Ageing 1.15.36 : 1.16.12 - School Morning Mantra 1.16.13 : 1.19.30 - Humble Beginnings 1.19.31 : 1.21.25 - Oz' Take Aways 1.21.26 : 1.22.35 - Raymond's Ambition 1.22.36 : 1.24.31 - Thank you and Wrap Up www: wordswithoz.com IG: @WordsWithOz

In this podcast, I chat with Kootsy about his discussions with Aboriginal and Torres Strait Islander men on going to the Doctor. He talks about the concept of being "half sick" and how the delivery of GP services doesn't work for many Indigenous guys; something that does nothing to address the gaps in health between Indigenous and non-Indigenous men. Kootsy, a sociology graduate, sees the benefits of gender-specific services. He says he didn't make it as a rugby player, so he is pursuing a career in research to make a difference to men's health and well-being. Kootsy is in his final year of his PhD at the Aboriginal Research Unit at the South Australian Health and Medical Research Institute.

Addiction and overdose deaths from opioids continue to grow. But the Army Medical Research Institute of Chemical Defense, located at the Aberdeen Proving Grounds, has been studying how medics would react if an enemy used opioids as a weapon. It's learned a lot. And now it's sharing that knowledge with first responders in the civilian world. Joining the Federal Drive with more, Maj. Gen. Randy Taylor, the senior mission commander of Aberdeen.

Addiction and overdose deaths from opioids continue to grow. But the Army Medical Research Institute of Chemical Defense, located at the Aberdeen Proving Grounds, has been studying how medics would react if an enemy used opioids as a weapon. It's learned a lot. And now it's sharing that knowledge with first responders in the civilian world. Joining the Federal Drive with more, Maj. Gen. Randy Taylor, the senior mission commander of Aberdeen.

This is Special English. I'm Mark Griffiths in Beijing. Here is the news.The recent WannaCry ransom ware outbreak across the world is the latest alarm about cyber security that demands immediate efforts at different levels, including international cooperation.It has been found that measures as simple as official Microsoft patch installation and security software update can work to fend off WannaCry in the largest cyber-attack in more than a decade. The hacking highlights the need for Internet users to heighten cyber security awareness.However, it also calls for systematic efforts as well as international cooperation to tackle cross-border challenges in a digitally connected world in order to affect a universal defense.A senior research fellow on cyber policy and security at Stanford University told the Xinhua News Agency that international cooperation on cyber security will be essential for a safer and more secure cyberspace.Herb Lin deplored the fact that countries have different views on how they intend to use cyberspace and the rules they want to apply have so far made it difficult to achieve international cooperation.Some experts foresee more attacks like WannaCry, which has hit more than 200,000 computers in some 150 countries since May 12. The vast majority of successful hacks require only the most basic techniques.This is Special English.Pharmaceutical company Merck recently won approval from the China Food and Drug Administration to sell its human papillomavirus vaccine, Gardasil, to help women fight cervical cancer.Developed by the US-based company in 2006, the vaccine has proved effective in protecting against the virus, better known as HPV, the chief cause of cervical cancer. The virus is found in almost all cervical cancer cases.Gardasil is the first HPV vaccine in the world and the second to be licensed for use in China.In July, Cervarix, an HPV vaccine developed by pharmaceutical GlaxoSmithKline, received approval to be sold on the Chinese mainland after almost 10 years of seeking approval.Gardasil is expected to be commercially available on the mainland in three to six months, which means women will no longer have to seek vaccinations outside of the mainland, in places such as Hong Kong.After breast cancer, cervical cancer is the second-most common cancer in women aged between 15 and 44 in China. China reports more than 130,000 cervical cancer cases a year, accounting for 28 percent of the global total.The HPV vaccine, as the first anti-cancer vaccine in the world, has proved effective in preventing cervical cancer and is seen as a breakthrough in the fight against the condition.Today, such vaccines are in use in around 120 countries and regions, including the United States, Australia and most European countries.You&`&re listening to Special English. I&`&m Mark Griffiths in Beijing.A 100-year-old medical technique could be used to achieve pregnancy in infertile women without the need for expensive in vitro fertilization treatments. That's according to researchers from the University of Adelaide and the South Australian Health and Medical Research Institute. The often overlooked historical technique, which involves "flushing" the woman&`&s fallopian tubes with iodised poppy seed oil, has been proven to be successful in aiding fertility.Research teams in Australia and the Netherlands say that the procedure, called HSG, was first carried out in 1917 and involved flushing the tubes with the oil during an X-ray. Professor Ben Mol from the University of Adelaide says that over the past century, pregnancy rates among infertile women reportedly increased after their tubes had been flushed with either water or oil during the X-ray procedure. Until now, it has been unclear whether the type of solution used in the procedure was influencing the change in fertility.He said the results have been even more exciting than scientists could have predicted, helping to confirm that an age-old medical technique still has an important place in modern medicine.According to the results of Mol&`&s study, around 35 percent of infertile women who underwent the procedure achieved successful pregnancies within six months of the HSG being performed.This is Special English.Some 1,730 new plant species were discovered globally in the last year, some of which have food and medicinal value. That's according to an annual report released recently by the Royal Botanical Gardens, Kew, based in England.Involving 128 scientists from 12 countries, RBG Kew&`&s State of the Worlds Plants report presents data never seen before on patterns affecting plants in different regions.New species of Manihot were discovered in Brazil that have the potential to be developed into better food crops, and new species of the climbing vine genus Mucuna, used in the treatment of Parkinson&`&s disease, were found in South East Asia and South and Central America.Kathy Willis, director of science at RBG Kew, says they have tried to make sure that this year&`&s State of the World&`&s Plants report goes beyond the numbers to look at the natural capital of plants -- how they are relevant and valuable to all aspects of our lives.The report also reveals that plants with thicker leaves and bark, more efficient water use, deeper roots, and higher wood density are better able to cope with future climate change.The report also highlights information on how new technology is helping to speed up the discovery and classification of plants that are providing important sign posts to the next food crops and actions in protecting some of the most important plant species globally.You&`&re listening to Special English. I&`&m Mark Griffiths in Beijing.Climate change is more real than ever. A new study has found a steady growth of moss in Antarctica over the past 50 years, and suggested that the continent will be greener in the future.The study was published recently in Current Biology, a scientific journal that covers all areas of biology. The research is led by Matthew Amesbury, a researcher at the University of Exeter in Britain.The Antarctic Peninsula might sound like a remote and untouched region, but the study showed that the effects of climate change are felt there, and it has been warming faster than the rest of the continent.The research team looked at 150 years&`& worth of data and found clear change points in the last 50 years, which showed the increase of moss cover. That could shift the ecosystem in Antarctica, driving it to simulate what has been observed in Arctic.Last month, the sea ice cover in the Arctic was record low, and that of Antarctic was near record low too, according to the U.S. National Oceanic and Atmospheric Administration.This is Special English.The World Economic Forum on the Middle East and North Africa has been held with calls for increased support for youth and addressing unemployment and poverty.Officials during the forum at the Dead Sea said providing financial and moral support to the youth in the Middle East and reforming education were key in addressing the pressing challenges facing the region.The forum attracted more than 1,100 political and business leaders from more than 50 countries. The participants agreed that the world is facing many problems including high unemployment rate, fast population growth and political regional challenges. The problems are relentlessly seeking to thrive on the hopelessness and despair of the younger generation. The forum said providing hope and support are vital for the youth in the region.Crown Prince Hussein of Jordan said at the forum that what young people need most is for all to take a bet on them, and to support them, morally and financially, so they can create their own impact.The forum agreed that as 31 percent of young people in the region are unemployed, new initiatives and urgent action are needed. You&`&re listening to Special English. I&`&m Mark Griffiths in Beijing. You can access the program by logging on to crienglish.com. You can also find us on our Apple Podcast. Now the news continues.More than 30 national library curators and representatives from 20 countries and regions in Asia and Oceania gathered in Beijing to discuss the building of sustainable regional library networks.The participants came from countries including Australia, Japan, the Philippines and Papua New Guinea. They shared their experience in international cultural exchanges at the two-day conference hosted by the National Library of China.The National Library of China is promoting the establishment of the "Silk Road" international library alliance, and most of the participating libraries are from countries along the ancient trading route.The annual conference is hosted in turn by the participating libraries. This year marks the third time that China has hosted the event.This is Special English.A Peking opera adaptation of the Western masterpiece "Faust" was staged recently in Germany's western city of Wiesbaden, starting its premiere tour in the country.The opera was co-produced by China National Peking Opera Company and Italy&`&s Emilia Romagna Theater Foundation. It was performed as part of the International May Festival, a world-known traditional theater festival.The opera is based on the Western masterpiece "Faust", written by Johann Wolfgang Goethe more than 200 years ago. The Peking Opera adaptation combines music, vocal performances, mime, dance, and acrobatics.Since its debut in 2015, the opera has been staged over 70 times worldwide. It offers a creative blend of Western classics with oriental culture as well as presents a perfect cooperation between Chinese artists and performers from Italy and Germany.The opera has been added to this year&`&s German-Chinese cultural program, a national event in Germany featuring the theme "China Today" to celebrate the 45th anniversary of diplomatic ties between the two countries. You&`&re listening to Special English. I&`&m Mark Griffiths in Beijing.The first International Tea Expo has been held in east China's Zhejiang province, attracting tea vendors and companies from both home and abroad.The expo is held in Hangzhou, the provincial capital, at the venue where the G20 Summit was held. Over 1,000 enterprises from more than 30 countries participated in the event.President Xi Jinping sent a congratulatory letter to be read at the opening ceremony, extending his hope that the expo would give exposure to Chinese tea culture. He said he hopes the event will grow into an important platform for exchanges and cooperation between China and the rest of the world.The letter also included a call for the expo to promote both the tea industry and tea culture.This is Special English.The first China-themed library in Mexico has opened in a bid to promote cultural exchange.Books on Chinese history, culture, medicine and music, as well as digital and video archives, can be found at the new Chinese Library at Mexico City&`&s Anahuac University.Officials from China and the prestigious private university were on hand to inaugurate the 14th library of its kind worldwide, as part of celebrations marking 45 years of diplomatic ties between the two countries.Chinese officials say the library provides an opportunity for Mexico to know China better. It will also be a new platform for deepening educational, academic and cultural exchange between the two countries.The library currently has 6,000 books and 80,000 digital archives with information on China&`&s politics, economy, culture, science and technology, as well as education and history.Special software is provided, in both Spanish and English, for those who wish to learn Mandarin Chinese.This is Special English.As part of the celebration to mark the 100th anniversary of the Russian Revolution, an exhibition about the revolution has opened at the British Library.（全文见周六微信。）

Arete Executive Podcast hosted by Managing Partner Richard Triggs. Interview with Frank Gannon, CEO, QIMR Berghofer Medical Research Institute. Richard Triggs LinkedIn: https://au.linkedin.com/in/richardtriggs Frank Gannon LinkedIn: https://au.linkedin.com/in/frank-gannon-4b67a529 Arete Executive website: www.areteexecutive.com.au QIMR website: http://www.qimrberghofer.edu.au/ Richard's book on Amazon: http://www.amazon.com.au/Uncover-Hidden-Job-Market-Executive-ebook/dp/B00WCQ5U46/ref=sr_1_1?ie=UTF8&qid=1445566942&sr=8-1&keywords=uncover+the+hidden+job+market LinkedIn CEO Incubator Group: https://www.linkedin.com/grps/CEO-Incubator-6948255/about? Theme music by Simon Gardner "Sunny" from the album "Choose Your Own Adventure": http://simongardnerguitarist.com

In this podcast Dr James Rudd talks to Professor Stephen Nicholls, consultant cardiologist and Deputy Director of the South Australian Health and Medical Research Institute in Adelaide, at the 2015 European Cardiology meeting in London. They discuss the next generation of lipid therapies and imaging as a surrogate marker of disease.

Could our Adelaide winter be a blessing for getting healthy? Professor Gary Wittert from the University of Adelaide thinks so and explains why as we talk to him about all manner of health topics as part of the SAHMRI opening. The South Australian Health and Medical Research Institute is celebrating its official opening this week and we chat with Gary about: The SAHMRI The Fat vs Sugar Q and A involving Tony Jones this week Whether South Australia should use indulgent food in its tourism advertising, given a growing awareness about cutting down on calories You'll even learn what section of the supermarket makes him angry, really angry! Chloe from Yelp is with us to undo the professor's work and guide us around five spots where you can avoid the cold and enjoy hearty, interesting meals - with or without tracky dacks! Brett poses a question: when is grooming too much grooming for men? He explains in the podcast and seeks your feedback, especially from women listeners. We note the launch of AdelaideFree City Wifi - enjoy it as you go about the CBD. Colin notes the large number of mobile phone offenses reported by South Australia Police recently, while Steve shares an inspiring quote from Michael Bollen from Wakefield Press about the true joy of a great book. And we have the largest Adelaide Visa Council history on record, all thanks to a probing tweet by the @WeAreADL account, being managed this week by Alexis from THE SHOW on PBA-FM. Support the show: https://theadelaideshow.com.au/listen-or-download-the-podcast/adelaide-in-crowd/ See omnystudio.com/listener for privacy information.

Crystallography, protein molecular structure, Hauptman-Woodward Medical Research Institute. In 1985, Dr. Herbert Hauptman was awarded the Nobel Prize in Chemistry. Although he is a mathematician by training who has taken only one chemistry course in his life, he was able to use classical mathematics to resolve a critical problem in chemistry. The structures of thousands of molecules have now been solved by crystallographers using Dr. Hauptman's methods.

Crystallography, protein molecular structure, Hauptman-Woodward Medical Research Institute. In 1985, Dr. Herbert Hauptman was awarded the Nobel Prize in Chemistry. Although he is a mathematician by training who has taken only one chemistry course in his life, he was able to use classical mathematics to resolve a critical problem in chemistry. The structures of thousands of molecules have now been solved by crystallographers using Dr. Hauptman's methods.