Podcasts about Acumen

Princess Noor Pahlavi was born into the Iranian royal family as the eldest child of the Crown Prince. She heard the call to civic duty from an early age, inspired by the legacy of her grandfather, the last Shah of Iran, along with her grandmother, The Empress of Iran. But she was not content to sit on the sidelines, and decided to use her place of privilege to be a voice for progressive change for the people of Iran. Princess Noor joined host Jay Ruderman to speak about her distinctive path in continuing the legacy of her family through advocacy for a democratic Iran. Princess Noor talks about the struggles and resilience of the women of Iran, as well as her advocacy for gender equality and better access to healthcare for women. Jay and Princess Noor also speak about her efforts to support Iranians living under the Islamic Republic, along with her work with organizations that empower and support oppressed women. Episode Chapters (00:00) Intro to Princess Noor Pahlavi (01:16) Stories of the Shah and The Empress of Iran (06:54) The Current Islamic Regime in Iran (10:33) Life for Iranians Under the Regime (15:25) Women's Rights and Health in Iran (22:40) Advocacy for Iranian Women Abroad (25:04) Noor's Work at Acumen (27:52) Leveraging Her Platform for Change (29:04) Conclusion and Credits For video episodes, watch on www.youtube.com/@therudermanfamilyfoundation Stay in touch: X: @JayRuderman | @RudermanFdn LinkedIn: Jay Ruderman | Ruderman Family Foundation Instagram: All About Change Podcast | Ruderman Family Foundation To learn more about the podcast, visit https://allaboutchangepodcast.com/

Do you ever feel like you're just going through the motions at work, unsure about the exact strategy to guide your decisions? This episode will change that.In the business world, the word “strategy” is quite the buzzword. But what does it really mean to think and lead strategically? And what can you do as a manager to get better at it?If you want to stop wasting time and start making powerful strategic decisions no matter your position, today's guest is here to unpack everything you need to know about being strategic.Today's guest is Rich Horwath, CEO of the Strategic Thinking Institute. Over the past 20 years, Rich has helped more than one million managers around the world learn how to think, plan, and act strategically. He is a New York Times bestselling author of 8 books on strategy and his vision is to teach the world to be strategic.In this episode, Rich shares his insights on how strategy is often misunderstood and why it's crucial for everyone—from individual contributors to senior leaders—to think strategically.He breaks down the difference between strategy and tactics, explaining how understanding the distinctions can lead to better decision-making. He also shares a practical framework for everyday strategic thinking and how to manage your time, allocate resources wisely, and pivot when necessary to stay on coursePlus, in the extended episode available to Podcast+ members, Rich delves into what isn't strategic thinking and the tools that will help you act more strategically.Join the conversation now!Get FREE mini-episode guides with the big idea from the week's episode delivered to your inbox when you subscribe to my weekly email.Conversation Topics(00:00) Introduction(00:23) The difference between strategy and tactics explained(04:10) Why strategy matters at every level of the organization(06:08) The 3 As framework: Acumen, Allocation, and Action(07:57) What it looks like to apply the 3 As framework in practice(12:06) Making smart decisions through resource allocation(18:34) How to stay strategic in a constantly changing environment(22:39) A real-world example: Adjusting tactics to align with strategy(25:30) A great manager Rich has worked for(26:39) Keep up with Rich(27:27) [Extended Episode Only] What it looks like when you're not being strategic(30:59) [Extended Episode Only] Tools to help you act more strategicallyAdditional Resources:- Get the extended episode by joining The Modern Manager Podcast+ Community for just $15 per month- Read the full transcript here- Follow me on Instagram here - Visit my website for more here- Upskill your team here- Subscribe to my YouTube Channel here Keep up with Rich Horwarth- Follow Rich on LinkedIn here- Subscribe to his YouTube channel here- Listen to the Strategic Minds Podcast here- Check out StrategicThinking Institute here for moreBook Giveaway - 5 copies of Strategic AND Free White Paper on DelegationRich is giving away five copies of his book STRATEGIC: The Skill to Set Direction, Create Advantage, and Achieve Executive Excellence, which Inc. Magazine described as “A top 4 must read business book to kick off the year.” In the book, Rich shares practical tools, tips, and techniques he's developed over two decades that can help you think, plan, and act strategically in every area of your business. And, members of Podcast+ can download Rich's White Paper: Lead at Your Level, which addresses the importance of delegation to a leader's success. In the article, Rich shares the four factors that are crucial to effective delegation and the ability to unlock dozens of hours of extra time each year.To get this bonus and many other member benefits, become a member of The Modern Manager Podcast+ Community.---------------------The Modern Manager is a leadership podcast for rockstar managers who want to create a working environment where people thrive, and great work gets done.Follow The Modern Manager on your favorite podcast platform so you won't miss an episode!

This was a clever Wednesday crossword, and not just because its author, Peter A. Collins, slipped 21A, Understanding, KEN, and 22D, Astuteness, ACUMEN, into the grid. It was, inevitably, the theme that made this crossword shine, and you'll discover the meta-joke in that assessment when listening to today's episode (or when you've solved the crossword, whichever comes first).Show note imagery: Members of the G6 - France, Germany, Italy, Poland, Spain, and the United KingdomWe love feedback! Send us a text...Contact Info:We love listener mail! Drop us a line, crosswordpodcast@icloud.com.Also, we're on FaceBook, so feel free to drop by there and strike up a conversation!

In this episode of The Friday Habit, Mark sits down with Steve Van Diest, President of Acumen's Front Range region, to unpack the highs and lows of his entrepreneurial journey. From founding a thriving mattress business to launching a customizable pillow company, Steve's path has been anything but linear.Steve candidly shares his experiences with burnout, making costly business decisions, and the challenges of building a healthy company culture. He opens up about the turning points that led him to give away a profitable business and the lessons he now imparts to other business owners through his work at Acumen.Key Takeaways:Burnout Isn't Just a Buzzword: Steve reflects on how ignoring signs of burnout led to poor decisions and how he's learned to identify and address it earlier.Trust, But Verify: The consequences of partnering without proper agreements and how a lack of structure nearly cost Steve his business.Building a Culture of Transparency: Why Steve prioritized hiring people with strong values over sales experience and how that shaped his company's identity.The Power of Community: How being part of a peer advisory group transformed Steve's approach to business – and why every entrepreneur should seek out similar connections.Connect with Steve:Website: Acumen ImpactLinkedIn: Steve Van DiestLearn More:Visit TheFridayHabit.com for show notes, resources, and to download the guide on working on your business rather than in it.Stay Connected:Subscribe to The Friday Habit for more real-life business lessons, candid conversations, and actionable strategies to elevate your entrepreneurial journey.

Let's look over how well Arch Manning commanded the play-action offense and what Texas did on 4th down in 2024. Join InsideTexas.com: https://www.on3.com/teams/texas-longhorns/join/ This Video Brought to You By Our Wonderful Sponsors: Shop Academy Sports + Outdoors for top brands and low prices, with FREE in-store pickup and same-day delivery! Visit https://www.academy.com/ Injured? Call Andre The lawyer at 214-444-8808. Located in Dallas, TX, Andre helps injured Longhorns in car wrecks, slip and falls, 18 wheeler accidents, on the job injuries, and wrongful deaths. https://andrethelawyer.com/ Want Official IT Merch? Shop Here: https://insidetexasmerch.myshopify.com/ Listen to the Podcast: Spotify: https://open.spotify.com/show/3P0cwAUPNZrsNrTOKOfa6x Apple: https://podcasts.apple.com/us/podcast/inside-texas-football/id1721623113 Find Us On Social Media: Twitter: https://twitter.com/InsideTexas Facebook: https://www.facebook.com/InsideTexas/ Instagram: https://www.instagram.com/insidetexas/

This content is for informational and entertainment purposes only, you should not construe any such information or other material as legal, tax, investment, financial, or other advice.----------------------------------------In this episode, I had the pleasure of speaking with Jacqueline Novogratz, Founder & CEO of Acumen on her global journey that led her from the world of international banking to the heart of social entrepreneurship—beginning in Rwanda, and now reaching 650+ million lives through Acumen's work around the world.From Chase Bank to Kigali: A Journey Rooted in EmpathyJacqueline's journey began not with a grand strategy, but with a moment of clarity while working in Rwanda in the late 1980s, where she helped launch one of the country's first microfinance institutions.There, she witnessed how markets could be harnessed to empower individuals—especially women—but also saw how fragmented and fragile traditional aid systems were."Access isn't enough; capability is key."That idea would eventually become Acumen.The Founding of Acumen: Bridging Markets and PhilanthropyFounded in 2001, Acumen was created to tackle what Jacqueline calls "the blue flame" space—the gap between pure philanthropy and market-driven capitalism. Acumen uses “patient capital” to invest in entrepreneurs solving problems in energy, agriculture, healthcare, education, and workforce development."We need to reframe what risk means in investing."Acumen has since invested over $150 million into companies that have impacted millions of people in low-income communities across Africa, South Asia, Latin America, and the U.S. But the goal isn't just scale—it's systemic change.What It Takes to Build Markets That Work for the PoorJacqueline explains that creating sustainable impact requires far more than capital—it demands a deep understanding of local contexts, cultural norms, and the lived experiences of the communities being served."The status quo exists for a reason; change is hard."She emphasizes that real progress depends on:Entrepreneurial courageLong-term thinkingCollaboration with governments and civil societyAcumen works to build "markets with moral imagination", where value creation doesn't come at the cost of human dignity or environmental degradation.Education, Circular Impact, and the Future of Social EntrepreneurshipAnother major focus of Acumen is education. Through the Acumen Academy, they've trained over 1,800 social enterprise leaders, equipping them with tools in moral leadership, storytelling, and systems thinking.Jacqueline envisions a circular economy of impact investing, where capital flows to and from communities, creating sustainable, inclusive systems over time."Resilience and moral imagination are essential qualities for social entrepreneurs."She sees the future of impact rooted in innovative partnerships—between private and public sectors, startups and institutions, and across geographies.A Legacy of Courage and CompassionAs Jacqueline looks ahead, her message is clear: we need a new moral framework for capitalism—one that measures success not just in returns, but in human dignity and long-term value for society.Her story is a reminder that systems can change, markets can heal, and entrepreneurs—when supported with the right kind of capital and community—can solve the world's most pressing problems. ----------------------------------------Thrive in the Impact Economy.Join 20k+. Subscribe to our weekly newsletter for the latest news, exclusive interviews, and curated products that drive the Impact Economy. Our mission is to highlight and celebrate the founders, creators, investors, and conscious brands shaping the future of conscious business and philanthropy.To learn more, please visit causeartist.com

Drew Hiss, Chairman of Acumen, discusses his unique journey from founding Acumen to rejoining the CEO ranks within another organization. Dive into Drew's origin story, learning from entrepreneurial challenges and the critical role of community and wise counsel in achieving business success. Together, Drew and host Dan Cooper explore the values driving Acumen, the power of aligning peers with shared principles, and the innovative tools and strategies Drew implemented during his time as a CEO. Discover how Drew navigated organizational transformations, built a cohesive leadership team, and balanced the dynamics of personal faith and professional excellence. This episode offers rich insights into leadership, the journey of growth, and the transformative impact of staying connected to purpose and community in business endeavors.

Welcome to Episode 35 of Magic Moments ✨   In this moment, I sat down with the brilliant Orrin - an absolute powerhouse when it comes to finance and business. He's got a solid foundation in the corporate world (three years of CIMA under his belt and five years grinding in finance), and he's since taken that knowledge and turned it into entrepreneurial gold.   We discussed the stuff that most people shy away from - what to do when your business hits tough financial times. And it's not about hiding or powering through silently. It's about honesty and transparency. Orrin shared how being upfront and open with partners, investors, and teams can actually make or break your business when the pressure's on.   We also dived into why every entrepreneur needs to get comfortable with the numbers. Finance isn't just for the accountants anymore - it's a core part of decision-making, and if you want to lead with confidence, you've got to understand what's under the hood of your business.    Orrin's lived that transition from financial specialist to full-on business leader, and he drops some epic insight on how that shift works - and why CFOs are often stepping up as CEOs more and more.   This conversation was a proper eye-opener, and if you're navigating the chaos of entrepreneurship (especially with money stress in the mix), this one's definitely for you.   Did you enjoy this Magic Moment? Click here to listen to the full episode.  

Do you understand your business and the value you add as an admin or EA? Listen to this episode if you want to start elevating your financial and business acumen for career advancement. Recorded at EA Ignite Fall 2024 and produced by the American Society of Administrative Professionals - ASAP. Learn more and submit a listener question at asaporg.com/podcast.

How can we use the tools of the marketplace and business to solve the problems that lead to poverty? That's where patient capital comes in. Jacqueline Novogratz, the CEO of Acumen, explains how her venture capital fund's long term investments, which prioritize social progress along with financial returns, have positively impacted 650 million people across the globe. She and Ilham discuss the most inspiring companies Acumen has invested in; the importance of kindness and patience in business; achieving audacity AND humility when working towards one's goals; how storytelling is key to success, and so much more. Timestamps1:42 - Inspiration for solving the problems of poverty3:39 - Becoming a banker6:18 - Founding Acumen and the emergence of patient capital8:59 - How to build sustainable and profitable companies12:47- Most inspiring companies Acumen invests in16:23 - The beauty of Acumen's manifesto20:05 - The importance of storytelling25:37 - Pushing back against the naysayers29:46 - Embracing the beautyJacqueline Novogratz is an entrepreneur, an author and quite frankly a beacon of light in the world. She is the founder and CEO of Acumen, a nonprofit global venture capital fund that uses entrepreneurial approaches to address global poverty by investing in companies with the purpose. She is the author of Manifesto for a Moral Revolution: Practices to Build a Better World and The Blue Sweater: Bridging the Gap Between Rich and Poor in an Interconnected World. For additional details about the podcast, show notes, and access to resources mentioned during the show, please visit https://www.syensqo.com/en/podcast

This episode explores the role of protection magic as a historically grounded response to war, oppression, and systemic violence across diverse cultural and temporal contexts.Drawing on peer-reviewed academic sources, it examines how magical practices—rituals, talismans, verbal formulae, and spirit invocations—have been used as forms of spiritual defence and political resistance. From Mesopotamian anti-witchcraft rites and Greco-Roman defensive curses to medieval Christian amulets, Renaissance grimoires, and the Magical Battle of Britain, the lecture situates protection magic within broader religious, social, and cosmological frameworks.Special attention is given to non-Western and postcolonial contexts, including the ritual technologies of Haitian Vodou during the revolution, Obeah in the British Caribbean, Yoruba warrior rites, and Andean protective ceremonies. The discussion also considers contemporary expressions of magical protection, including digital activist magic, Chaos Magic, and the esoteric disciplines of Damien Echols under carceral conditions.CONNECT & SUPPORT

Stéphane Timpano is CEO of ASPIRE, the program management and business development arm of the Advanced Technology Research Council located in Abu Dhabi. The ATRC's mission is to build a vibrant research and development ecosystem that supports Abu Dhabi—and the broader UAE—in its transformation into a knowledge-based economy. With nearly 1,000 employees representing over 70 nationalities, the Council is also investing in the next generation of innovators through a wide range of STEM initiatives. ASPIRE drives the Council's programmatic efforts by crowdsourcing top global talent through international competitions and grand challenges. These challenges are designed to tackle real-world problems—everything from global hunger and maritime safety to the future of autonomous mobility—by bringing together experts from academia and industry to co-create cutting-edge solutions. As CEO, Stéphane leads ASPIRE's strategic direction and oversees relationships with key stakeholders and partners. He brings more than 15 years of management consulting experience, including major transformation initiatives at Bain & Company in Dubai and Nigeria. His industry expertise spans telecom, media, tech, private equity, and energy. Before consulting, Stéphane worked in the media industry in South Africa and Italy, gaining valuable experience at Sky Italia News Corporation and IMS. He has also been deeply involved in social impact and economic development projects with organizations such as the World Bank, Gates Foundation, Acumen, and Endeavor. He holds an MBA from SDA Bocconi in Milan and a degree in Business Administration from Aix-Marseille University in France. Recently, more than 2,500 people gathered to watch top autonomous drone racers compete for a $1 million prize pool at the Autonomous Drone Racing Grand Championship in Abu Dhabi.  And in case you were wondering, MavLab, from the Delft University of Technology in the Netherlands, secured victories in three out of four competitions. They clinched the AI Grand Challenge with their drone completing two laps of the 170-metre course in just 17 seconds. MavLab won the world's first AI-only drag race, demonstrating straight-line speed and precision under intense acceleration.  And in a landmark moment, MavLab's autonomous drone defeated three top DCL champion pilots in a head-to-head AI-versus-human showdown. With precision flying, the AI-powered drone edged out its human-piloted rivals in thrilling contests.  In this episode of the Drone Radio Show, Stéphane shares insights into ASPIRE's mission, the rise of autonomous racing challenges, and the broader impact these competitions can have across technology, education, and industry.

The Wyrd Mountain Gals Show "In Which The Gals Show Off Their Technical Acumen During A Formal Business Meeting" Episode Airs Wednesday, 4-16-25  7PM EST The gals let you in on one of their high-powered & energetic business meetings.   We hope you can keep up...   #WyrdMountainGals #ByronBallard #Asheville #DigitalWitchery

start set the show00:06:00 Grizzlies highlights00:08:00 Grizzlies snap losing streakJa's big nightJa's gestures00:34:00 Lang WhitakerBraves strugglesGrizzlies beat HeatTuomas Iisalo's coaching acumen01:01:00 DJ Zirk01:22:00 NBA stuff01:27:00 Men's/women's Final Four

Trust is eroding over time in our public institutions. The Acumen Edelman Trust Barometer reveals 67% of New Zealanders express a sense of grievance with business, media, government and NGOs – surpassing the global average of 61%. Many feel overlooked by those in power and disillusioned as a result Acumen Chief Executive Adelle Keely says it's a wake-up call for those in charge. She says for the past few years, businesses have been the most trusted institution - but this year for the first time, no institutions are trusted at all. Keely told Mike Hosking it's a worldwide trend. LISTEN ABOVE See omnystudio.com/listener for privacy information.

In this episode of the "HR Mixtape," host Shari Simpson welcomes Paul Butler, Client Partner at Newleaf Training and Development. They delve into the critical importance of financial acumen for HR professionals, emphasizing how understanding financial metrics can enhance decision-making and drive business success. Paul shares insights from his extensive experience, highlighting the need for HR to partner with finance to maximize organizational performance. Key Takeaways: Financial literacy is essential for HR professionals to align human resources with business results. Building relationships with finance colleagues can create a safe space for HR to ask questions and improve their financial understanding. Implementing zero-based budgeting encourages a more strategic approach to financial planning and resource allocation. Tune in to learn how HR can leverage financial insights to foster a more effective workplace! Guest(s): Paul Butler, Client Partner, Newleaf Training and Development Book: Business Financial Intelligence: A mindset and skillset few people have and all organizations need.

Yasmina Zaidman is the Chief Development and Partnerships Officer at Acumen, a non-profit that uses an investment approach to fund entrepreneurs to decrease poverty. Yasmina also describes her career journey and shares advice for people who want to make a sustainable difference in global issues.

Yasmina Zaidman, Chief Development and Partnerships Officer at Acumen, describes how they invest in entrepreneurs to alleviate poverty.

Seth Godin – acclaimed entrepreneur, bestselling author of This is Strategy: Make Better Plans, and closing keynote speaker at ATD25 – joins the podcast to challenge the way we think about strategy.  What if strategy isn't about rigid plans but about systems, time, and the games we choose to play? What happens when we mistake false proxies for progress? And how can community action and empathy fit into the puzzle of creating change?  Seth shares his perspective on navigating ambiguity, designing upskilling and reskilling strategies for roles that don't yet exist, and building a future-ready workforce.  And for a sweet bonus? A little chocolate talk for dessert.

Fred Jentgen is launching a new Acumen team in Phoenix, Arizona! Fred shares his journey from a technology leader to an EOS implementer and founder of Unleashed Consulting Group. The conversation dives into the challenges and learning experiences Fred faced throughout his career, particularly leading through tragedy. He recounts the story of a key team member, Eric, who battled cancer at a young age, and how the team rallied together during this difficult time. Fred discusses the importance of role clarity, trust, and communication, and how these elements helped the team to persevere through adversity. Fred also touches on his personal faith journey and how it integrates with his professional life, offering hope and guidance during life's toughest moments. This episode is a deep dive into how leaders can prepare for and navigate through unexpected challenges while supporting their teams with empathy and understanding.

Check out the Youtube Video!   CBQ - “What does a healthy executive ego look like? And why is that NOT the default?”   “Purpose did not protect leaders from their ego when their sense of stability was at risk.” - Dr. Tiffany Brandreth.   Dr. Tiffany Brandreth, Organizational Transformation Consultant & Coach , joins us in person (and on Youtube!) to talk about ego, purpose and power dynamics in the workplace.   Transform your Senior Leadership Team - www.drtiffanybrandreth.com  

Cover 2 with Blaine and Zach - Hour 1 - Trusting Brian Callahan's QB Development AcumenSee omnystudio.com/listener for privacy information.

Cover 2 with Blaine and Zach - Hour 1 - Trusting Brian Callahan's QB Development AcumenSee omnystudio.com/listener for privacy information.

Leadership is challenging, and it is even more challenging when you're in an impact and servant hearted type of role. As we enter into 2025 and leaders are focused on impact, we set aside time with Steve Van Diest of Acumen to discuss some key trends that servant hearted leaders will face as they seek impact in 2025. Steve brings a wealth of experience and ministry, business, investing, and coaching. His work with Acumen gives him a special angle and viewpoint on the challenges that leaders are facing today. To learn more, check out acumenimpact.com/ Feast Over Famine does not provide legal, tax, accounting or other professional advice. You should consult professional advisors concerning the legal, tax, or accounting consequences of your activities. Feast Over Famine does not consult, advise, or assist with (i) the offer or sale of securities in any capital-raising transaction, or (ii) the direct or indirect promotion or maintenance of a market for any securities. Feast Over Famine does not engage in any activities for which an investment advisor's registration or license is required under the U.S. Investment Advisors Act of 1940, or under any other applicable federal or state law; or for which a “broker's” or “dealer's” registration or license is required under the U.S. Securities Exchange Act of 1934, or under any other applicable federal or state law.  

We love to hear from our listeners. Send us a message. Life Science Leader's Ben Comer and Acumen Pharmaceuticals' Dr. Jim Doherty join the Business of Biotech to discuss Dr. Doherty's lifelong, singular focus on researching therapeis for CNS diseases. We cover the historical challenges associated with the development of new therapeutics for Alzheimer's disease, advances in the space, the controversies that have ensued on the heels of recent amlyloid-targeting drug approvals, and where Acumen Pharmaceuticals and its lead candidate, Sabirnetug, fit on the landscape. We also cover the critical and growing role of biomarkers in matching Alzheimer's therapies to specific patients, and assess the growing demand for CNS therapeutics. Access this and hundreds of episodes of the Business of Biotech videocast under the Listen & Watch tab at bioprocessonline.com. Subscribe to our monthly Business of Biotech newsletter. Get in touch with guest and topic suggestions: matt.pillar@lifescienceconnect.comFind Matt Pillar on LinkedIn: https://www.linkedin.com/in/matthewpillar/

Join us for a captivating conversation with Justin Coke, the dynamic CEO and founder of 7 to 7 Dental, as he unveils the strategic maneuvers behind scaling healthcare practices through private equity partnerships. Discover why partnering with GTCR Private Equity was a game-changer for his business and learn about the meticulous due diligence process that ensured alignment with the right financial partner. Unpack the apprehensions healthcare executives face when considering private equity, and gain insights into maintaining control while accelerating growth in the competitive healthcare landscape.We dive deep into the art of crafting a robust healthcare business model centered on patient access and scalability. Listen as Justin shares the strategic advantages of having a unique story and a process-driven approach that enhances negotiation power and maximizes business value. Hear about the critical transition from cash-based to accrual accounting, a move that not only boosts company valuation but also attracts sophisticated buyers. As Justin discusses the transition, he emphasizes the significance of compliance and thorough preparation for smoother business operations and transitions.Explore the broader financial landscape with us as Justin discusses the impact of low-interest rates on Dental Service Organizations and the resulting market corrections. Learn the lessons of cautious financial planning and the dangers of excessive reliance on borrowed money. From strategic growth decisions to the timing of business sales, this episode is packed with practical advice and compelling stories for healthcare professionals and executives looking to navigate the complex world of private equity partnerships and healthcare expansion.If you need help finding the perfect location or your ready to invest in commercial real estate, email us at admin@leadersre.com Sign up for a FREE vulnerability analysis and lease renewal services View our library on apple podcasts or REUniversity.org. Connect on Facebook. Commercial Real Estate Secrets is ranked in the top 50 podcasts on real estate

Dr. Eric Siemers, Medical Officer at Acumen Pharma, is developing a monoclonal antibody called sabirnetug that targets a specific toxic form of amyloid beta, Aβ oligomers. These oligomers are now believed to be a key driver of neuronal damage in Alzheimer's disease. The drug is in phase 2 clinical trials to evaluate its ability to slow cognitive decline in early-stage Alzheimer's patients and demonstrate the accuracy of biomarkers in identifying pathology before symptoms appear.   Eric explains, "We've identified, and this is a monoclonal antibody, a monoclonal antibody with a unique mechanism of action in that it targets what are called Aβ oligomers. And without going into all the details, these Aβ oligomers are now really felt to be the toxic species, the ones that cause the neurons to die, and the two drugs that have recently gotten approval sort of indirectly get at those toxic species, maybe one more than the other. But in our case, we're directly targeting what we think is the most toxic species. And so the progress in the field is wonderful, and nobody can say that it's not, or take anything away from that, but nobody's cured the disease either. Now we know we've got a toehold, we know an approach, and Acumen is using an antibody because of this unique target. We think of it as a next-generation treatment for Alzheimer's disease." "We've known about these Alzheimer's plaques for a long time, but what's more recent is understanding some of these intermediate species. And so these Aβ oligomers we target are oligo, meaning a few. So, anywhere from 2 to 200 of these Aβ stuck together. The Aβs are basically inherently sticky. And so the things we're most interested in are probably 10 of the Aβ together up to say 50, which seems to be the sweet spot." #AcumenPharmaceuticals #Alzheimers #ALZ #EndALZ #Sabirnetug #DrugDevelopment acumenpharm.com Download the transcript here

Dr. Eric Siemers, Medical Officer at Acumen Pharma, is developing a monoclonal antibody called sabirnetug that targets a specific toxic form of amyloid beta, Aβ oligomers. These oligomers are now believed to be a key driver of neuronal damage in Alzheimer's disease. The drug is in phase 2 clinical trials to evaluate its ability to slow cognitive decline in early-stage Alzheimer's patients and demonstrate the accuracy of biomarkers in identifying pathology before symptoms appear.   Eric explains, "We've identified, and this is a monoclonal antibody, a monoclonal antibody with a unique mechanism of action in that it targets what are called Aβ oligomers. And without going into all the details, these Aβ oligomers are now really felt to be the toxic species, the ones that cause the neurons to die, and the two drugs that have recently gotten approval sort of indirectly get at those toxic species, maybe one more than the other. But in our case, we're directly targeting what we think is the most toxic species. And so the progress in the field is wonderful, and nobody can say that it's not, or take anything away from that, but nobody's cured the disease either. Now we know we've got a toehold, we know an approach, and Acumen is using an antibody because of this unique target. We think of it as a next-generation treatment for Alzheimer's disease." "We've known about these Alzheimer's plaques for a long time, but what's more recent is understanding some of these intermediate species. And so these Aβ oligomers we target are oligo, meaning a few. So, anywhere from 2 to 200 of these Aβ stuck together. The Aβs are basically inherently sticky. And so the things we're most interested in are probably 10 of the Aβ together up to say 50, which seems to be the sweet spot." #AcumenPharmaceuticals #Alzheimers #ALZ #EndALZ #Sabirnetug #DrugDevelopment acumenpharm.com Listen to the podcast here

After the Detroit Lions and their fans invade Lucas Oil Stadium and take a 24-6 win home with them, Caleb welcomes Jack Arthur and Connor Arthur to the podcast. The two Lions fans traveled down with the Zuver's for the game and there's plenty to hash out. What was a day with the Zuver's like, are Lions fans reasonable and where do both teams go from here? Follow, share, rate and review Indiana Drive!Contact The Show Here!Email: 20czuver@gmail.com

This week on The Nick Halaris Show we are featuring Yasmina Zaidman, the Chief Development and Partnerships Officer at Acumen, a pioneer and global leader in social impact investing.  Acumen—probably the coolest, most inspiring organization I've ever come across—is dedicated to using the power of entrepreneurship and patient capital to solve some of our world's most intractable issues.  Over the last several decades, they have invested $250M in over 200 companies and have materially improved the lives of an estimated 650M people all over the world. Ready to dive in? Listen to this episode on Apple Podcasts, Spotify, Amazon Music and YouTube or on your favorite podcast platform. I wanted to have Yasmina on the show to learn more about Acumen's inspiring work, unpack her experiences working at the forefront of this incredible movement and see what lessons we can find to improve our own mission-driven efforts.   As you'll see in the episode, Yasmina is quite a passionate and inspiring leader and has a wealth of knowledge about what works and what doesn't when it comes to trying to solve big issues.  Our conversation left me wanting to drop everything and join the team at Acumen.   Tune in to this inspiring episode to learn:  • Why Acumen is so focused on supporting entrepreneurship as a way to engage in philanthropy • Why promoting agency and dignity is so important in the fight to eliminate poverty• How Acumen uncovered the secret to building entrepreneurial capacity in the most economically disadvantaged communities in the world• What patient capital is and how it can play a crucial role in the broader philanthropic and capitalist ecosystem• Why Acumen is so focused on building sustainable businesses that promote energy access, education, and sustainable agriculture • & Much, much more Stay tuned to the end to learn why Yasmina is calling for a new paradigm for global leadership, one that prioritizes collective needs over individual desires, and discover why she believes that the key to true and lasting success is to find ways to merge your values with your aspirations. 

In this episode, Reed Nyffeler and cohost, Art Calderon, discuss the complex yet essential skill of financial acumen for business leaders. The episode explores how to distinguish between emotional and tangible value in financial decisions, emphasizing sustainability and long-term returns. Through practical examples and personal anecdotes, the hosts delve into the significance of making informed financial decisions by auditing past expenses and evaluating the worth and sustainability of investments. They also address the differences between personal and business financial acumen, highlighting the importance of understanding sacrifice and risk in decision-making. Tune in for a helpful guide on developing financial acumen to align with strategic planning and ultimately achieve your organization's vision. Highlights Financial acumen is about understanding worth and sustainability.Emotional value can cloud financial decision-making.Leaders must balance cost and value in their decisions.Equity can be more expensive than taking on debt in business.Every financial decision requires some form of sacrifice.Understanding personal vs. business finance is crucial for leaders.Risk-taking is essential for potential high returns.Evaluating past spending helps improve future financial decisions.Financial worth should guide business investments.Long-term returns are more valuable than immediate gratification.

Nonprofit Sector Faces Legislative and Financial Challenges Amid Innovative Solutions In this episode of Nonprofit News Feed, George Weiner, Chief Whaler of Whole Whale, and Nick Azulay, Digital Strategist, delve into pressing issues and inspiring initiatives in the nonprofit sector. They begin with the failed U.S. House bill H.R. 9495, which sought to give the Treasury Department unilateral power to revoke nonprofits' 501(c)3 status if deemed to support terrorism. Although the bill was defeated, the discussion highlights concerns over due process and the potential for abuse, emphasizing the need for vigilance in protecting nonprofit rights. Next, the duo explores a Los Angeles Times story about nonprofits facing financial strains due to the city's mansion tax. Two organizations, the Motion Picture and Television Fund and Los Angeles Jewish Health, incurred significant taxes despite their missions aligning with affordable housing goals. This situation underscores the complexities of nonprofit tax laws and the need for legislative reform to prevent financial burdens that hinder mission-driven work. Shifting focus to solutions, the hosts discuss Bloomberg's report on Acumen's ambitious $1.5 billion investment in agricultural technology startups across developing nations. This initiative aims to enhance climate resilience and improve yields for small-scale farmers, marking a significant shift from traditional aid models to sustainable, systems-based approaches. Finally, a feel-good story from CBS News highlights "Adventures in Training with a Purpose," a nonprofit offering wellness services to veterans and first responders. Founded by former Pittsburgh Steelers player John Kalb, this organization provides comprehensive support to improve mental and physical health, celebrating its impact with a fundraising event featuring Steelers legends. Critical Insights: The defeat of H.R. 9495 demonstrates the power of civil society in protecting nonprofit rights, but ongoing vigilance is necessary. Legislative gaps, like those seen in the LA mansion tax, can impose unintended financial burdens on nonprofits, highlighting the need for reform. Acumen's investment exemplifies a strategic shift towards sustainable development in agriculture, addressing significant funding gaps in climate resilience. Call to Action: Nonprofit professionals and advocates are encouraged to stay informed about legislative developments and support initiatives that drive systemic change. Engaging in policy discussions and advocating for reform can help protect and empower the sector. Closing Thought: As challenges persist, the nonprofit sector's resilience and innovation continue to shine. By fostering collaboration and leveraging strategic investments, the sector can navigate obstacles and create lasting impact.

Nonprofit Sector Faces Legislative and Financial Challenges Amid Innovative Solutions In this episode of Nonprofit News Feed, George Weiner, Chief Whaler of Whole Whale, and Nick Azulay, Digital Strategist, delve into pressing issues and inspiring initiatives in the nonprofit sector. They begin with the failed U.S. House bill H.R. 9495, which sought to give the Treasury Department unilateral power to revoke nonprofits' 501(c)3 status if deemed to support terrorism. Although the bill was defeated, the discussion highlights concerns over due process and the potential for abuse, emphasizing the need for vigilance in protecting nonprofit rights. Next, the duo explores a Los Angeles Times story about nonprofits facing financial strains due to the city's mansion tax. Two organizations, the Motion Picture and Television Fund and Los Angeles Jewish Health, incurred significant taxes despite their missions aligning with affordable housing goals. This situation underscores the complexities of nonprofit tax laws and the need for legislative reform to prevent financial burdens that hinder mission-driven work. Shifting focus to solutions, the hosts discuss Bloomberg's report on Acumen's ambitious $1.5 billion investment in agricultural technology startups across developing nations. This initiative aims to enhance climate resilience and improve yields for small-scale farmers, marking a significant shift from traditional aid models to sustainable, systems-based approaches. Finally, a feel-good story from CBS News highlights "Adventures in Training with a Purpose," a nonprofit offering wellness services to veterans and first responders. Founded by former Pittsburgh Steelers player John Kalb, this organization provides comprehensive support to improve mental and physical health, celebrating its impact with a fundraising event featuring Steelers legends. Critical Insights: The defeat of H.R. 9495 demonstrates the power of civil society in protecting nonprofit rights, but ongoing vigilance is necessary. Legislative gaps, like those seen in the LA mansion tax, can impose unintended financial burdens on nonprofits, highlighting the need for reform. Acumen's investment exemplifies a strategic shift towards sustainable development in agriculture, addressing significant funding gaps in climate resilience. Call to Action: Nonprofit professionals and advocates are encouraged to stay informed about legislative developments and support initiatives that drive systemic change. Engaging in policy discussions and advocating for reform can help protect and empower the sector. Closing Thought: As challenges persist, the nonprofit sector's resilience and innovation continue to shine. By fostering collaboration and leveraging strategic investments, the sector can navigate obstacles and create lasting impact.

In this episode of The Leader Assistant Podcast, Maggie Olson talks about how to build financial acumen in your role so you can be more confident in conversations and projects related to the finance world.Show notes -> leaderassistant.com/296Sponsor -> leaderassistant.com/novaMore from The Leader Assistant... Book, Audiobook, and Workbook -> leaderassistantbook.com Premium Membership -> leaderassistant.com/membership Events -> leaderassistantlive.com Free Community -> leaderassistant.com/community

Money expert Lisa Dudson is along to explain what "lifestyle creep" is, how it can take you by surprise and what to do about it. Lisa Dudson is the owner of Acumen.co.nz. Her advice is of a general nature.

Host Dan Cooper sits down with Curt Sampson, Head of Growth for Monarch Inventory Services and Growth Catalyst at Acumen, to explore the intricate relationship between CEOs and COOs. As these roles are often referred to as the 'visionary' and 'integrator,' understanding their dynamic is crucial for business growth and success. Curt shares insights from his diverse career, starting from his days with large corporations like Hallmark and Newell Rubbermaid to his journey as a consultant and entrepreneur. He delves into the importance of aligning visions, executing strategies, and maintaining healthy tension between the CEO and COO to drive business forward. The discussion touches on the significance of communication, setting clear objectives, and the role of core values in achieving alignment. Whether you're a CEO considering the need for an operator or a COO navigating your position, this episode offers valuable takeaways on building a successful leadership team.

In this bonus episode of What the Fundraising, please enjoy an episode of the System Catalyst podcast with Jeff Walker and English Sall. They interview Jacqueline Novogratz, founder and CEO of Acumen, a global leader in impact investing.  Jacqueline shares her journey over the past 30 years, exploring how Acumen uses innovative patient capital to create real systems change. By investing in companies that tackle critical issues like climate change, energy access, and poverty alleviation, Acumen has provided pathways for social entrepreneurs to thrive. In this episode, you'll hear: The origins and evolution of impact investing, with Acumen at the forefront. How patient capital fuels long-term social change. The necessity of partnerships with governments, corporations, and investors. Jacqueline's reflections on building systems that prioritize people, dignity, and moral imagination. If you like what you hear, Follow this link to subscribe to System Catalysts. System Catalysts is produced by Hueman Group Media.  Get all the resources from today's episode here.  Connect with me:  Instagram: https://www.instagram.com/_malloryerickson/ Facebook: https://www.facebook.com/whatthefundraising YouTube: https://www.youtube.com/@malloryerickson7946 LinkedIn: https://www.linkedin.com/mallory-erickson-bressler/ Website: malloryerickson.com/podcast Loved this episode? Leave us a review and rating here: https://podcasts.apple.com/us/podcast/what-the-fundraising/id1575421652 If you haven't already, please visit our new What the Fundraising community forum. Check it out and join the conversation at this link. If you're looking to raise more from the right funders, then you'll want to check out my Power Partners Formula, a step-by-step approach to identifying the optimal partners for your organization. This free masterclass offers a great starting point. Learn more about your ad choices. Visit megaphone.fm/adchoices

  Princess Noor Pahlavi was born into the Iranian royal family as the eldest child of the Crown Prince. She heard the call to civic duty from an early age, inspired by the legacy of her grandfather, the last Shah of Iran, along with her grandmother, The Empress of Iran. But she was not content to sit on the sidelines, and decided to use her place of privilege to be a voice for progressive change for the people of Iran. Princess Noor joined host Jay Ruderman to speak about her distinctive path in continuing the legacy of her family through advocacy for a democratic Iran. Princess Noor talks about the struggles and resilience of the women of Iran, as well as her advocacy for gender equality and better access to healthcare for women. Jay and Princess Noor also speak about her efforts to support Iranians living under the Islamic Republic, along with her work with organizations that empower and support oppressed women.   Episode Chapters (00:00) Intro to Princess Noor Pahlavi (01:16) Stories of the Shah and The Empress of Iran (06:54) The Current Islamic Regime in Iran (10:33) Life for Iranians Under the Regime (15:25) Women's Rights and Health in Iran (22:40) Advocacy for Iranian Women Abroad (25:04) Noor's Work at Acumen (27:52) Leveraging Her Platform for Change (29:04) Conclusion and Credits   For video episodes, watch on www.youtube.com/@therudermanfamilyfoundation   Stay in touch: X: @JayRuderman | @RudermanFdn LinkedIn: Jay Ruderman | Ruderman Family Foundation Instagram: All About Change Podcast | Ruderman Family Foundation To learn more about the podcast, visit https://allaboutchangepodcast.com/  See omnystudio.com/listener for privacy information.

Nicolle Wallace is joined by Mark Cuban, Stephanie Ruhle, Sarah Longwell, Cornell Belcher, Matt Dowd, John Heilemann, Vaughn Hillyard, Amanda Carpenter, and Paul Reickhoff.

Canada's own Keesa K joins the Hear K Tell podcast to share her story of success. As a former student-athlete and founder of Hoop Queens, her story resonates with entrepreneurs and athletes. Hoop Queens aims to provide athletic & personal development opportunities for women in sport, create representation for the future generation of female athletes and provide mental and emotional support for athletes throughout their journey.

Welcome to another episode of Predictable B2B Success! Today, we're diving deep into the core of financial management for businesses with Colin Sanburg, an expert whose unique approach aims to transform how companies manage their finances and drive profitability. Colin, the founder of FinElevate, joins host Vinay Koshy to discuss the intricacies of integrating team training with leadership collaboration, creating comprehensive dashboards, and aligning financial strategies with a company's values and vision. In this episode, Colin explains why many entrepreneurs struggle with financial literacy and how simplifying complex financial concepts can lead to better business decisions. He will also share his secret to holistically evaluating business ideas and investments, ensuring long-term success. Discover why mastermind groups are crucial for continuous learning and business growth and how embracing financial transparency can transform your team's understanding and engagement. We'll also explore Colin's compelling insights on utilizing AI in financial management, the critical role of effective marketing, and the importance of maintaining diverse lead generation channels. Whether you're a seasoned business owner or just starting, this episode provides indispensable advice to help you elevate your financial acumen and achieve predictable success in your B2B endeavors. Tune in now for a masterclass on driving business excellence with Colin Sanburg. Some areas we explore in this episode include: Ongoing Team Development: Integrating natural team training with leadership teams to build dashboards and drive profitability.Financial Literacy and Management: The importance of financial knowledge for business longevity and success, especially in competitive fields like B2B tech.Simplifying Financial Concepts for Entrepreneurs: Using simplified terms and a straightforward profit formula for better financial comprehension.Mastermind Groups: The value of engaging in mastermind groups for business growth, sharing experiences, and gaining practical insights.Financial Literacy in B2B Marketing: Addressing the gap in financial literacy among B2B marketers and the implications for business growth.The Role of Dashboards in Business: Tracking business performance through comprehensive dashboards for metrics like expenses, lead flow, and close rates.AI in Financial Management: The evolving role and custom applications of AI in financial management, and the importance of balancing AI with human effort.Colin Sanburg's Journey: His personal business journey, experience with financial instability, and commitment to continuous learning.Accounting Firm Philosophy: A shift from traditional CPA roles to a business-focused approach in accounting to help businesses improve profitability.Basic Financial Skills for Business Owners: The necessity for business owners to enhance their financial management skills and understanding key drivers of profitability.And much, much more...

In this episode of AI + a16z, Ambience cofounder and chief scientist Nikhil Buduma joins Derrick Harris to discuss the nuances of using AI models to build vertical applications (including in his space, health care), and why industry acumen is at least as important as technical expertise. Nikhil also shares his experience of having a first-row seat to key advances in AI — including the transformer architecture — which not only allowed his company to be an early adopter, but also gave him insight into the types of problems that AI could solve in the future.Here's an excerpt of Nikhil explaining the importance of understanding your buyer:"If you believe that the most valuable companies are going to fall out of some level of vertical integration between the app layer and the model layer, [that] this next generation of incredibly valuable companies is going to be built by founders who've spent years just obsessively becoming experts in an industry, I would recommend that someone actually know how to map out the most valuable use cases and have a clear story for how those use cases have synergistic, compounding value when you solve those problems increasingly in concert together. "I think the founding team is going to have to have the right ML chops to actually build out the right live learning loops, build out the ML ops loops to measure and to close the gap on model quality for those use cases. [But] the model is actually just one part of solving the problem. "You actually need to be thoughtful about the product, the design, the delivery competencies to make sure that what you build is integrated with the right sources of the enterprise data that fits into the right workflows in the right way. And you're going to have to invest heavily in the change management to make sure that customers realize the full value of what they're buying from you. That's all actually way more important than people realize."Learn more:Fundamentals of Deep LearningFollow everyone on X:Nikhil BudumaDerrick Harris Check out everything a16z is doing with artificial intelligence here, including articles, projects, and more podcasts.

Joining hosts Patty McCord and Jessica Neal this week is the founder and CEO of nonprofit global venture capital fund Acumen, Jacqueline Novogratz.Listen in as they discuss the impact of investing in entrepreneurs, and creating meaningful change in the world.Do you have an ongoing work issue you need guidance solving? Or maybe you want to know how Patty and Jess would have dealt with a past problem. Share your stories and questions with our producers here.TruthWorks is hosted by Jessica Neal and Patty McCord. The show is edited, mixed and produced by Megan Hayward and Mik Finnegan. Our Production Manager is Kathleen Speckert. TruthWorks is an editaudio production.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Amy is joined by Emily Nielsen Jones & Kazi Mghendi to discuss their project -- The Girl Child and Her Long Walk to Freedom -- a faith-based organization seeking to spread awareness, share resources, and organize women and allies to push back against global patriarchy.Emily Nielsen Jones is a donor-activist engaged in promoting human equality, justice, and peace around the world. She is particularly passionate and engaged in the nexus of faith, gender, and development and working to mobilize our faith traditions to more fully and unambiguously embrace gender equality. In her role at the Imago Dei Fund, Emily has helped the foundation to adopt a “gender-lens” in its grantmaking with a particular focus on partnering with inspired female change agents, locally and around the world, to build bridges of peace and create a world where girls and women can thrive and achieve their full human potential. Emily brings a contemplative posture to both faith and philanthropy and is passionate about supporting the inner lives of change agents to lead with love and be their best selves in the challenging work they do.Emily is actively engaged in the women-led philanthropy movement, and is the author of numerous articles. She is the recipient of the Christians for Biblical Equality 2013 Micah Award and was named a 2014 Women's eNews “21 Leaders of the 21st Century” honoree. Emily has served on various boards including the Boston Women's Fund, Women Thrive, New England International Donor Network, Girl Rising, Union Theological Seminary, Nomi Network Campaign Leaders Council, and Sojourners Founders' Circle. Emily has a BA in Government from Dartmouth College and a Master's in Educational Policy from Boston University. She is a trained Spiritual Director through both the Selah Spiritual Direction Certificate Program and the Still Harbor Spiritual Direction Practicum.Kazi Mghendi is passionate about leadership development at all levels and uses her experience and expertise to identify and support community-led solutions to ending injustices caused by poverty and inequalities. With over 12 years of experience in humanitarian, leadership training, social development, community development, and financial inclusion, she leverages her expertise to solve some of the world's challenging and complex issues, including improving education standards in rural communities in Kenya. Kazi joins The Girl Child & Her Long Walk to Freedom team as a Project Manager to support the project and its mission to liberate our societies from patriarchal beliefs, values, and cultures that have seen girls and women as lesser humans in society for generations. Her focus and passion is in international development, leadership coaching, fundraising, partnerships/relationship management, project/program management, systems design, and strategic thinking to solve community challenges.Kazi founded Elimu Fanaka, a non-profit organization impacting public primary schools in rural underserved communities in Kenya through improving access to quality education and using systems change to create sustainable communities. She previously worked at Acumen, managing their East Africa Fellows Program and Academy, at Ongoza Institute as Stakeholder Engagement Manager, and at Adaptive Change Advisors as a Project Manager. She holds a bachelor's degree in International Development with a concentration in Integrated Community Development from Daystar University and a Master's in International Relations – Diplomacy and Foreign Affairs at the United States International University.

Next episode is the 200th, therefore this is the 199th. I raid the 66 pages of ideas for episodes I have been keeping for nearly a decade, and present to you 199 that I have not yet made into podcasts (except for this one). Find the episode's transcript, plus more information about the topics therein, at theallusionist.org/199ideas. NEWSLUSIONIST: The new Allusionist live show Souvenirs is on tour in the UK right now! Rush to theallusionist.org/events for tickets and dates. And if you fancy concocting a quiz question for the imminent 200th episode, go to theallusionist.org/quiz to submit it; your deadline is 6 September 2024. To help fund this independent podcast, take yourself to theallusionist.org/donate and become a member of the Allusioverse. You get regular livestreams with me and my collection of reference books, inside scoops into the making of this show, watchalong parties eg the new season of Taskmaster featuring my brother Andy, and the company of your fellow Allusionauts in our delightful Discord community.  This episode was produced by me, Helen Zaltzman, with music and editorial assistance from Martin Austwick of palebirdmusic.com. Find @allusionistshow on Instagram, Facebook, Threads, Bluesky, TikTok, YouTube etc. Our ad partner is Multitude. If you want me to talk about your product or thing on the show, sponsor an episode: contact Multitude at multitude.productions/ads. This episode is sponsored by: • Home Chef, meal kits that fit your needs. For a limited time, Home Chef is offering Allusionist listeners eighteen free meals, plus free shipping on your first box, and free dessert for life, at HomeChef.com/allusionist.• Squarespace, your one-stop shop for building and running your online empire/new home for your cryptic puzzle that takes months to solve. Go to squarespace.com/allusionist for a free 2-week trial, and get 10 percent off your first purchase of a website or domain with the code allusionist. • Bombas, whose mission is to make the comfiest clothing essentials, and match every item sold with an equal item donated. Go to bombas.com/allusionist to get 20% off your first purchase.  • LinkedIn Ads convert your B2B audience into high quality leads. Get $100 credit on your next campaign at linkedin.com/allusionist.Support the show: http://patreon.com/allusionistSee omnystudio.com/listener for privacy information.

Join Steve Van Diest, co-host of the Sharpen Podcast by Acumen, as he invites his wife, Christine Van Diest, to share about the unique challenges and rewards of being married to an entrepreneur! Christine, a business owner herself, shares her invaluable perspective and experiences from their 31-year journey together. Christine discusses the emotional and logistical hurdles of supporting an entrepreneurial spouse, especially during the early years of business startups. She offers practical advice on maintaining a balanced family life, effective communication, and the importance of personal growth for both partners. This episode is a must-listen for entrepreneurial couples seeking to thrive both in business and in their personal lives. Tune in for heartfelt insights and actionable tips to navigate the complexities of marriage and entrepreneurship.

Merriam-Webster's Word of the Day for August 9, 2024 is: acumen • AK-yoo-mun • noun Acumen refers to keenness and depth of perception, discernment, or discrimination—in other words, the ability to think clearly and make good decisions, especially in practical matters. // The fictional detective possesses a superior acumen that enables her to solve the most bizarre and puzzling of mysteries. See the entry > Examples: "Industrial agriculture's hidden costs are precisely the ones agroecology makes explicit. Its pathways reward the acumen of those on the front lines, support the livelihoods of the poor and protect the biodiversity of the planet." — Raj Patel, Scientific American, 22 Sept. 2021 Did you know? A keen mind and a sharp wit can pierce confusion as easily as a needle passes through cloth. Remember this analogy between a jabbing needle and piercing perception, and you will readily recall the history of acumen. The English word retains the spelling and figurative meaning of its direct Latin ancestor acūmen, which literally means "sharp point." That word comes in turn from the Latin acuere, a verb meaning "to sharpen" that is related to acus, the Latin word for "needle." Acuere puts the acu- (gesundheit!) in a number of English words, including acute, acuity, and acuminate. In its earliest English uses, acumen referred specifically to a sharpness of wit. In modern English, it conveys the sense that someone is perceptive enough to grasp a situation quickly and clever enough to deftly apply that insight.

Money expert Lisa Dudson joins Paddy to talk insurance: what kind do you need, how much should you insure yourself for, how can you keep premiums under control and what things could get it voided? Lisa Dudson is the owner of Acumen.co.nz. Her advice is of a general nature.

A favourite quote of mine, a call to action really and one that I reference in How to Begin, is “give more to the world than you take.” Jacqueline Novogratz said it, and she's the founder of Acumen a venture capital firm that invests in non-profits making the world a better place.  I find it powerful because it's about the long game. Over your lifetime, give more than you take. There are some seasons when you need to harvest, of course. You trying to build a good life for yourself. But there should be other seasons when you plant, and when you build. Adam Grant's first book was about giving and taking, and the core insight from that book is that people who give, paradoxically, tend to be the most successful, so long as they give in a sustainable way. The people who give without boundaries tend to fail over time. I suspect on balance that many of us could get better at giving. I also know that for many of us, we have to learn to also receive. Get book links and resources at http://2pageswithmbs.com and subscribe to the 2 Pages newsletter at https://2pageswithmbs.substack.com. Kumi Naidoo reads two pages from Letters to my Mother. [reading begins at 20:56] Hear us discuss: “My area of focus right now is very much asking the question, what will it take for activism to win bigger and faster? And if I write that up as a book, I'll probably call it The Reflections of a Failed Activist.” [09:10] | “When we think about health and self-care, we tend to often think more about physical health and we're not sufficiently ready. to embrace the idea that we are dealing with a colossal global mental health crisis right now, from eco-anxiety, from climate anxiety, and also just a sense of injustice that people feel.” [19:42] | "Vulnerability is expressing strength and courage, not an acknowledgment of weakness and failure." [35:12] | "Activism is about people who look at the world, say 'this is an injustice,' and contribute in a way that makes a difference." [37:14] | "The moment of history we find ourselves in, pessimism is a luxury we simply cannot afford." [42:51]

This episode is a two-for-one, and that's because the podcast recently hit its 10-year anniversary and passed one billion downloads. To celebrate, I've curated some of the best of the best—some of my favorites—from more than 700 episodes over the last decade. I could not be more excited. The episode features segments from episode #124 "Jamie Foxx on Workout Routines, Success Habits, and Untold Hollywood Stories" and #514 "Jacqueline Novogratz on Building Acumen, How to (Actually) Change the World, Speaking Your Truth, and the Incredible Power of 'Dumb' Questions"Please enjoy!Sponsors:ExpressVPN high-speed, secure, and anonymous VPN service: https://www.expressvpn.com/tim (Get 3 extra months free with a 12-month plan)AG1 all-in-one nutritional supplement: https://DrinkAG1.com/Tim (1-year supply of Vitamin D (and 5 free AG1 travel packs) with your first subscription purchase.)The League curated dating app for busy, high-performing people: https://www.theleague.com/; available on iOS and AndroidTimestamps:[06:50] Notes about this supercombo format.[07:53] Enter Jamie Foxx.[08:19] When Jamie met Kanye West.[10:58] Why Jamie considers his studio magical.[13:32] When Jamie met Ed Sheeran.[15:00] What's on the other side of fear?[16:53] Making impressions.[22:15] How Eric Marlon Bishop became Jamie Foxx.[24:49] Overcoming fear at open mics.[26:12] Could Prince or Michael Jackson find a career break in today's "Age of Memes?"[27:49] How Jamie learned to read the room.[33:27] Why do some comedians lose the ability to make people laugh?[39:04] Enter Jacqueline Novogratz.[39:37] Jacqueline's background and siblings' accomplishments.[42:06] Jacqueline's journey into social impact investing.[45:15] An early banking career and reputation for asking tough questions.[48:36] A tendency to champion underdogs.[53:18] From banker to disruptor.[1:00:04] Jacqueline's first opportunity in her new path.[1:05:28] Failures, small wins, and perseverance.[1:09:21] Jacqueline's first real win in Rwanda.[1:13:37] The path between Rwanda and founding Acumen.[1:16:06] Jacqueline's reasons for applying to Stanford Business School.[1:18:10] How the Rwanda genocide redefined poverty for Jacqueline.[1:20:42] Lessons Jacqueline learned about human nature from the genocide.[1:26:25] Acumen's three main functions and naming process.[1:29:12] The quantification of impact investment through Lean Data.[1:37:28] Alternative names for Acumen that got left on the cutting room floor.[1:40:43] The concept of moral imagination.[1:44:55] An early win at Acumen.[1:50:43] Advice for young people aspiring to create positive change.[1:53:20] The benefits of committing to something larger than oneself.[1:56:10] Characteristics of a good mentor.[1:59:36] Book recommendations.[2:02:48] Advice for impact investors at various levels.[2:09:20] Next steps for investors to start making a difference.[2:14:00] Jacqueline's authenticity.[2:17:07] A taste of potential topics for a future round two.[2:20:55] Parting thoughts.*For show notes and past guests on The Tim Ferriss Show, please visit tim.blog/podcast.For deals from sponsors of The Tim Ferriss Show, please visit tim.blog/podcast-sponsorsSign up for Tim's email newsletter (5-Bullet Friday) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Discover Tim's books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissYouTube: youtube.com/timferrissFacebook: facebook.com/timferriss LinkedIn: linkedin.com/in/timferrissPast guests on The Tim Ferriss Show include Jerry Seinfeld, Hugh Jackman, Dr. Jane Goodall, LeBron James, Kevin Hart, Doris Kearns Goodwin, Jamie Foxx, Matthew McConaughey, Esther Perel, Elizabeth Gilbert, Terry Crews, Sia, Yuval Noah Harari, Malcolm Gladwell, Madeleine Albright, Cheryl Strayed, Jim Collins, Mary Karr, Maria Popova, Sam Harris, Michael Phelps, Bob Iger, Edward Norton, Arnold Schwarzenegger, Neil Strauss, Ken Burns, Maria Sharapova, Marc Andreessen, Neil Gaiman, Neil de Grasse Tyson, Jocko Willink, Daniel Ek, Kelly Slater, Dr. Peter Attia, Seth Godin, Howard Marks, Dr. Brené Brown, Eric Schmidt, Michael Lewis, Joe Gebbia, Michael Pollan, Dr. Jordan Peterson, Vince Vaughn, Brian Koppelman, Ramit Sethi, Dax Shepard, Tony Robbins, Jim Dethmer, Dan Harris, Ray Dalio, Naval Ravikant, Vitalik Buterin, Elizabeth Lesser, Amanda Palmer, Katie Haun, Sir Richard Branson, Chuck Palahniuk, Arianna Huffington, Reid Hoffman, Bill Burr, Whitney Cummings, Rick Rubin, Dr. Vivek Murthy, Darren Aronofsky, Margaret Atwood, Mark Zuckerberg, Peter Thiel, Dr. Gabor Maté, Anne Lamott, Sarah Silverman, Dr. Andrew Huberman, and many more.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.