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Acne scars aren't just a skin issue—they impact confidence, self-esteem, and how we show up in the world. In this episode, Dr. Mina is joined by internationally recognized dermatologist Dr. Mehrnoosh Heidarian to unpack the full scope of acne scarring: from its emotional toll to the latest, evidence-based treatment options. They break down the different types of scars (boxcar, ice pick, rolling, keloids), why early intervention matters, and how personalized treatment plans like subcision, laser-assisted techniques, and microneedling can make all the difference. You'll also hear how social media is shaping skincare myths, the truth about collagen-boosting treatments, and what it really takes to heal acne scars from the inside out. Key Takeaways - Acne scarring has a significant emotional impact on patients. - 95% of acne patients may develop scars at some point. - Different types of acne scars require tailored treatment approaches. - Subcision is a minimally invasive procedure for treating scars. - Laser-assisted techniques can enhance treatment outcomes. - Emotional well-being is a crucial aspect of acne scar treatment. - Customized treatment plans are essential for effective results. - Combining various treatment modalities can yield better outcomes. - Understanding the patient's skin type is vital for treatment success. - The goal of treatment is to make scars as invisible as possible. Expect significant improvement, not a 100% cure for acne scars. - Ice pick scars require specific treatment techniques like cross technique. - Precision is crucial when treating darker skin types. - Microneedling is effective, but radiofrequency microneedling is preferred. - Hypertrophic and keloid scars need careful management and follow-up. - Post-treatment care is essential for optimal healing. - Trust the process and follow your dermatologist's advice. - Acne scar treatment is a journey that takes time. - Social media can spread misinformation about skincare. - Professional guidance is necessary to set realistic expectations. Dr. Mehrnoosh Heidarian, MD Board-Certified Dermatologist | Acne Scar Specialist Dr. Mehrnoosh Heidarian is a board-certified dermatologist with over 20 years of experience in cosmetic dermatology, specializing in acne scar treatment. Based in Tehran, she leads a private practice known for natural results through advanced, evidence-based procedures. She is best known for developing the Laser-Assisted Subcision technique for acne scars, with published research in a leading European aesthetic journal. Dr. Heidarian has presented at major international conferences including SCALE (Nashville), MOA (San Diego), ELEA (Italy), and TAS (Las Vegas), where she serves as an invited faculty speaker. A member of ASDS and ASLMS, Dr. Heidarian is also a globally recognized dermatology influencer with nearly 250,000 followers across social media. Follow Dr. Mehrnoosh Heidarian here: https://www.instagram.com/drheydarian?igsh=MWFhMjZnbHE4bG4xaw== Follow Dr. Mina here:- https://instagram.com/drminaskin https://www.facebook.com/drminaskin https://www.youtube.com/@drminaskin https://www.linkedin.com/in/drminaskin/ For more great skin care tips, subscribe to The Skin Real Podcast or visit www.theskinreal.com Baucom & Mina Derm Surgery, LLC Website- https://www.atlantadermsurgery.com/ Email - scheduling@atlantadermsurgery.com Contact - (404) 844-0496 Instagram - https://www.instagram.com/baucomminamd/ Thanks for listening! The content of this podcast is for entertainment, educational, and informational purposes and does not constitute formal medical advice.
Check out Dr. Mina's top picks for skin care here. In this conversation, Dr. Mina and Dr. Nicole Salame delve into the complexities of laser treatments in dermatology. They discuss the nuances of different laser technologies, the importance of provider expertise, and the safety considerations for patients. The conversation also highlights the need for patients to be informed about their providers' credentials and the specific lasers suitable for various skin types. Additionally, they explore innovative uses of lasers in treating medical conditions like skin cancer, emphasizing the potential benefits and limitations of these treatments. Key Takeaways: Lasers are customizable devices that target specific skin issues. Provider expertise is crucial for safe and effective laser treatments. Misconceptions about lasers being simple can lead to complications. Patients should prioritize safety and provider qualifications. Darker skin types can safely receive laser treatments with the right technology. Intense pulse light is risky for darker skin types. Lasers can be used innovatively for treating skin cancers. Understanding laser physics is essential for effective treatment. Patients should be aware of the potential for complications. Choosing the right provider can minimize risks and enhance outcomes. Patients often feel exhausted from frequent skin treatments. Laser resurfacing can treat precancers and rejuvenate skin. Non-ablative and ablative lasers are effective for skin health. Regular laser treatments can reduce skin cancer incidents. Choosing a board-certified dermatologist is crucial for skin care. A holistic approach to skin health leads to better results. De-influencing trends in skincare is important for patients. Innovative devices are changing the landscape of dermatology. The future of dermatology includes regenerative treatments. Understanding the difference between medical and cosmetic treatments is key. In This Episode: 03:06 Understanding Laser Technology 05:49 The Importance of Provider Expertise 09:10 Navigating Patient Safety and Complications 12:11 Choosing the Right Provider 15:04 Lasers for All Skin Types 18:00 Innovative Uses of Lasers in Medicine 22:30 The Emotional Toll of Skin Treatments 23:10 Laser Treatments for Skin Cancer Prevention 26:28 Choosing the Right Laser Treatment 31:08 The Importance of a Trusted Dermatologist 33:02 Innovations in Laser Technology 36:10 The Future of Regenerative Dermatology Nicole Salame, MD, FAAD is a double board-certified and fellowship-trained cosmetic dermatologist and Mohs micrographic surgeon. She attended college at the University of California, Los Angeles (UCLA) on numerous scholarships, graduating Cum Laude. She earned her MD from the University of California, Irvine (UCI) School of Medicine with induction into the Alpha Omega Alpha (AOA). She completed her dermatology residency at Emory University where she served as Chief Resident. Dr. Salame then completed an American Society of Dermatologic Surgery (ASDS)-accredited fellowship in Cosmetic Dermatologic Surgery at the prestigious SkinCare Physicians under the exceptional mentorship of innovators in the field. Dr. Salame is a Fellow of the American Academy of Dermatology (AAD), serves on several committees for the American Society for Laser Medicine and Surgery (ASLMS), and is an active member of the ASDS and Women's Dermatology Society (WDS). She has been a sub-investigator for numerous clinical trials and serves as a peer reviewer for Dermatologic Surgery and JAMA Dermatology. Her scholarly work has culminated in the authorship of over 30 peer-reviewed manuscripts and book chapters and more than 40 presentations at national conferences. Her expertise includes medical, procedural, and cosmetic dermatology with specialized-training in lasers, energy-based devices, injectables, regenerative dermatology, rejuvenation, and pre-juvenation. Follow Dr. Salame here: https://www.drnicolesalame.com/ https://www.instagram.com/dr.nicolesalame/ Follow Dr. Mina here:- https://instagram.com/drminaskin https://www.facebook.com/drminaskin https://www.youtube.com/@drminaskin https://www.linkedin.com/in/drminaskin/ For more great skin care tips, subscribe to The Skin Real Podcast or visit www.theskinreal.com Baucom & Mina Derm Surgery, LLC Website- https://www.atlantadermsurgery.com/ Email - scheduling@atlantadermsurgery.com Contact - (404) 844-0496 Instagram - https://www.instagram.com/baucomminamd/ Thanks for listening! The content of this podcast is for entertainment, educational, and informational purposes and does not constitute formal medical advice.
Today, I am delighted to connect with Dr. Omer Ibrahim, a board-certified, fellowship-trained dermatologist and the Co-director of Research at Chicago Cosmetics Surgery and Dermatology. Dr. Ibrahim completed his residency at the Cleveland Clinic. In our discussion today, we dive into the concept of hair loss in women, exploring how our hair follicles change during perimenopause and menopause, the prevalence of hair loss and hair thinning, and the many factors that contribute to it, including nutritional deficiencies, chronic stress, heat damage, weight loss (especially with GLP-1 medications), alcohol, and smoking. We discuss the benefits of hormone replacement therapy, essential supplements, red light therapy, PRP, exosomes, and topical and oral medications, and we also cover specific lab tests to request, the impact of endocrine-mimicking chemicals, and how to find qualified hair specialists or dermatologists in your area. You will not want to miss this conversation with Dr. Omer Inrahim, and I look forward to having him back on the podcast in the future. IN THIS EPISODE YOU WILL LEARN: The two most common reasons for hair thinning and hair loss How pattern hair loss, or TE, is linked to hormonal changes in perimenopause and menopause How hair loss patterns are not inherited directly, and how they can vary, even within the same family Why early treatment for hair loss is essential How weight loss and GLP-1 agonists can impact hair loss Vitamin deficiencies that could contribute to hair loss Why it's important to avoid harsh hair care practices to prevent hair damage How stress could lead to hair loss and thinning How alcohol and smoking impact hair loss Various prescription medications available for hair loss Bio: Dr. Omer Ibrahim Omer Ibrahim, MD FAAD, is a board-certified, fellowship-trained dermatologist and co-director of research at Chicago Cosmetic Surgery and Dermatology. He completed his residency at Cleveland Clinic, followed by an ASDS-accredited fellowship in cosmetic, laser, and dermatologic surgery at SkinCare Physicians in Boston. Dr. Ibrahim serves as adjunct faculty at Cleveland Clinic and Rush University, where he teaches residents the fundamentals of cosmetic and surgical dermatology. Connect with Cynthia Thurlow Follow on Twitter Instagram LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Connect with Dr. Omer Ibrahim Chicago Cosmetic Surgery and Dermatology On Instagram
Check out Dr. Mina's top picks for skin care here. In this week's episode, Dr. Mary Alice Mina and Dr. Shilpi Khetarpal discuss the intricacies of Platelet Rich Plasma (PRP) therapy, its applications in hair restoration, and the importance of a comprehensive treatment approach. Dr. Khetarpal explains the process of PRP, its effectiveness for various types of hair loss, and the significance of combining it with other treatments. The discussion also touches on the future of regenerative medicine, including the role of stem cells and exosomes, and emphasizes the need for patients to commit to ongoing care for optimal results. Key Takeaways: - PRP is derived from the patient's own blood and contains growth factors. - Injecting PRP into the scalp is the most effective method for hair restoration. - A series of PRP treatments is recommended for best results. - Hydration and overall health can influence the effectiveness of PRP. - PRP is safe and has a growing body of literature supporting its use. - Combining PRP with other treatments like minoxidil enhances results. - Exosomes and stem cells represent the future of regenerative medicine. - Patients should be aware of the commitment required for PRP treatments. - PRP can be used for areas beyond the scalp, such as eyebrows and beards. - Choosing a reputable provider is crucial for safe PRP treatment. Shilpi Khetarpal, MD is an ASDS fellowship-trained, board-certified dermatologist who is an associate professor in dermatology and the Director of Lasers & Cosmetic Dermatology at Cleveland Clinic. She did her dermatology residency at the Cleveland Clinic Foundation and an ASDS cosmetic fellowship at SkinCare Physicians in Chestnut Hill, MA. She has presented at both local and national professional meetings and has authored numerous book chapters in dermatologic textbooks and published many articles in peer-reviewed journals. She is actively involved in numerous organizations including the Women's Dermatologic Society, American Academy of Dermatology, American Society for Dermatologic Surgeons, Ohio Dermatological Association, and American Society for Laser Medicine and Surgery. She has been performing platelet rich plasma (PRP) for hair restoration and skin rejuvenation since 2016 and has performed over 2,000 procedures. Dr. Khetarpal has presented at both local and national professional meetings on PRP and microneedling and published a book in 2022 entitled An Aesthetic Clinician's Guide to Platelet Rich Plasma. Follow Dr. Khetarpal here: https://www.instagram.com/skindocsk?igsh=MTF3OTR0YmR2eGcyaQ== Follow Dr. Mina here:- https://instagram.com/drminaskin https://www.facebook.com/drminaskin https://www.youtube.com/@drminaskin https://www.linkedin.com/in/drminaskin/ For more great skin care tips, subscribe to The Skin Real Podcast or visit www.theskinreal.com Baucom & Mina Derm Surgery, LLC Email - scheduling@atlantadermsurgery.com Contact - (404) 844-0496 Instagram - https://www.instagram.com/baucomminamd/ Thanks for listening! The content of this podcast is for entertainment, educational, and informational purposes and does not constitute formal medical advice.
Hair loss isn't just about vanity—it's about confidence, identity, and health. Yet, despite being a billion-dollar industry, so much misinformation surrounds it. Why do so many treatments fail? Why do some dermatologists avoid it? And most importantly, what actually works?Hair loss is often dismissed as a cosmetic issue, but for millions of people, it's deeply personal and frustrating to treat. In this episode, this week I talk with Dr. Omer Ibrahim, a leading dermatologist, to break down the real science behind hair loss and hair thinning, especially in women. From postpartum shedding to perimenopausal hair loss and PCOS-related thinning, we explore the complex factors that influence hair health and why most treatments aren't a one-size-fits-all solution.Dr. Ibrahim shares why many dermatologists don't prioritize hair loss treatment, the role of stress and nutritional deficiencies, and why early intervention is key. We also dive into cutting-edge treatments—from oral minoxidil and exosomes to laser therapy and PRP injections—and whether hair transplants are actually worth it.If you've ever felt dismissed or confused about your hair loss, this episode is packed with expert insights that will help you advocate for the right care.Episode Highlights:Why hair loss isn't taken seriously in dermatologyThe biggest myths about hair thinning (and what actually works)How postpartum, perimenopause, and PCOS impact hair healthThe latest treatments, from oral minoxidil to exosomesWhy early intervention is crucial (and when to seek help)Enjoyed this episode? Don't forget to subscribe, like, and leave a comment! Your support helps us continue bringing expert insights to the conversation.Dr. Ibrahim's bio:Omer Ibrahim, MD FAAD is a board-certified, fellowship trained dermatologist and co-director of research at Chicago Cosmetic Surgery and Dermatology. He completed his residency at Cleveland Clinic, followed by an ASDS-accredited fellowship in cosmetic, laser and dermatologic surgery at SkinCare Physicians in Boston. Dr. Ibrahim serves as adjunct faculty at Cleveland Clinic and Rush University where he teaches residents the fundamentals of cosmetic and surgical dermatology.Get in Touch with Dr. Ibrahim:Website InstagramGet in Touch with Dr. Rahman:WebsiteInstagramYoutube
"We estimate about 8,000 metric tonnes of solvent per year are used by the industry to support solvent-based spray drying. That's a significant impact on cost, maintenance, safety and the environment," says Elizabeth Hickman, CEO of AustinPx, highlighting a critical sustainability challenge in pharmaceutical manufacturing.Elizabeth Hickman brings extensive experience in pharmaceutical contract manufacturing to her new role as CEO of AustinPx, having worked with several CDMOs and held leadership positions focused on developing innovative pharmaceutical technologies and business strategies.In a recent interview, Elizabeth discusses how AustinPx's innovative KinetiSol technology is eliminating the need for toxic solvents in pharmaceutical manufacturing while improving drug performance and reducing costs in the realm of amorphous solid dispersions (ASDs). She also shares insights on leadership and diversity in the pharmaceutical CDMO sector.Read the full article on PharmaSource
On this week's episode Kyla and Paul look at the systemic issues with ASDs and their operating procedures. From science of the ASD to the physical capability of the general population, they show us what issues exist for this kind of testing. Check out the "Lawyer Told Me Not To Talk To You" T-shirts and hoodies at Lawyertoldme.com and "Sit Still Jackson" at sitstilljackson.com Follow Kyla Lee on Twitter: twitter.com/IRPlawyer Follow Kyla Lee on Instagram: instagram.com/kylaleelawyer www.vancouvercriminallaw.com
In our second CHD Spotlight episode, we'll discuss holes in the heart—atrial septal defects (ASDs), ventricular septal defects (VSDs) and more!Today's CHD Spotlight is on the most common type of heart defect commonly referred to as "holes in the heart." This episode features Dr. William Novick—an internationally-known cardiothoracic surgeon and the head of the Novick Cardiac Alliance, a nonprofit organization providing life-saving heart surgeries to children around the world.In this episode, Dr. Novick shares the names of some specific congenital heart defects (they are commonly referred to as "holes in the heart") and the treatment used to help people born with these heart defects survive and thrive. He also discusses some heart defects which commonly have a hole in their heart, as well.Former appearances by Dr. Novick on "Heart to Heart with Anna”Healing the Hearts of Croatia, Libya, Ecuador and Beyond: https://www.buzzsprout.com/62761/902730-healing-the-hearts-of-croatia-libya-ecuador-and-beyondDoctor Burnout in the CHD Community: https://www.buzzsprout.com/62761/2486885-doctor-burnout-in-the-congenital-heart-defect-communitySupport the showAnna's Buzzsprout Affiliate LinkBaby Blue Sound CollectiveSocial Media Pages:Apple PodcastsFacebookInstagramMeWeTwitterYouTubeWebsite
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.01.07.523095v1?rss=1 Authors: Tripathi, M. K., Ojha, S. K., Kartawy, M., Hamoudi, W., Aran, A., Amal, H. Abstract: Autism spectrum disorders (ASDs) include a range of developmental disorders that share a core of neurobehavioral deficits manifested by abnormalities in social interactions, deficits in communication, restricted interests, and repetitive behaviors. Several reports showed that mutations in different high-risk ASD genes, including SHANK3 and CNTNAP2, lead to ASD. However, to date, the underlying molecular mechanisms have not been deciphered, and no effective pharmacological treatment has been established for ASD. Recently, we reported a dramatic increase of nitric oxide (NO) in ASD mouse models. NO is a multifunctional neurotransmitter that plays a key role in different neurological disorders. However, its role in ASD has not yet been investigated. To reveal the novel molecular, cellular, and behavioral role of NO in ASD, we conducted multidisciplinary experiments using cellular and mouse models as well as clinical samples. First, we treated WT mice with an NO donor, which led to an autism-like phenotype. Next, we measured and found high levels of nitrosative stress biomarkers in both the Shank3 and Cntnap2 ASD mouse models. Treating both mouse models with a selective neuronal NO synthase (nNOS) inhibitor led to a reversal in the molecular, synaptic, and behavioral ASD phenotypes. Using a primary neuronal cell culture, we confirmed that NO is specifically involved in neurons in ASD pathology. Next, using genetic manipulations in the human SH-SY5Y cell line, we found that nNOS plays a key role in the pathology. Finally, we examined human plasma samples from 19 low-functioning ASD patients, compared to 20 typically developed volunteers, and found a significant elevation in the NO levels in the ASD patients. Furthermore, using the SNOTRAP technology, which is an innovative mass spectrometric method to identify the SNO-proteome (SNO: NO-mediated post-translational modification), we revealed that the complement systems in the synaptic and neuronal development processes are enriched in the ASD group. This work indicates, for the first time, that NO plays a pathological role in ASD development. Our findings will open future and novel directions to examine NO in diverse mutations on the autism spectrum as well as other neurodevelopmental disorders and psychiatric diseases. Most importantly, it suggests a novel treatment strategy for ASD. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC
The Vanderbilt Kennedy Center Treatment and Research Institute for Autism Spectrum Disorders (TRIAD) is dedicated to improving assessment and treatment services for children with autism spectrum disorders and their families while advancing knowledge and training. Since its inception and evolution, TRIAD has provided services to thousands of children and families throughout Tennessee and beyond. TRIAD programs address community needs for cutting-edge information, high-quality support, and innovative interventions for children with autism spectrum disorders. TRIAD's specialized outreach staff provides training and direct consultation in state-of-the-art behavioral and educational assessment and intervention strategies in schools throughout the region. TRIAD-directed research programs and affiliated research partnerships examine the causes and treatment of ASDs. Currently, these directed research and partner programs include projects related to the development of siblings of children with autism, the identification of genetic and core behavioral features of autism, the nature, and treatment of sleep disturbance in children with autism, the diagnosis of autism itself, early intervention with children at risk for autism, and understanding the health and well-being of parents with children with autism. Research conducted through TRIAD serves not only the scientific community at large in its quest to identify the development and causes of ASD but also guides best practices for families and professionals working with children with ASD. Connect to learn more: Website: https://vkc.vumc.org/vkc/triad/home For live workshops and online learning questions please email triad.doe@vumc.org For all other inquiries call (615) 322-7565 or email autismresources@vumc.org Facebook: https://www.facebook.com/VKCTRIAD/ Twitter: @VKCTRIAD As an Amazon Associate, I earn commissions from qualifying purchases. For more information about True North Disability Planning: Web: https://truenorthdisabilityplanning.com/ Podcast (ABC's of Disability Planning) - https://anchor.fm/abcs-disability-planning Waypoints - https://waypoints.substack.com/ Facebook: @TrueNorthDisabilityPlanning Twitter: @NeedsNavigator Resource store (free downloads too) - https://www.teacherspayteachers.com/Store/True-North-Disability-Planning Have a question or request for the podcast? Submit it here - https://forms.gle/yCDArzz85vTypMwh8 --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app --- Send in a voice message: https://anchor.fm/abcs-disability-planning/message
CardioNerds (Dan Ambinder), episode lead Dr. Sarah Fahnhorst (ACHD Cardiologist at Spectrum Health in Grand Rapids, Michigan), and series co-chair Dr. Agnes Koczo (fellow at UPMC) learn about ASD from Dr. Richard Krasuski (ACHD Cardiologist and Director of ACHD at Duke University). Audio editing by CardioNerds Academy Intern, student doctor Adriana Mares An atrial septal defect (ASD) is a common congenital heart disease most often diagnosed in childhood, but initial presentation can be in adulthood. ASDs are abnormal communications between the left and the right atrium. There are four types of ASDs with different embryologic origins. If the defects are large, they will require percutaneous or surgical closure. Unrepaired defects can lead to symptoms of shortness of breath, exercise intolerance, recurrent chest infections, or pulmonary hypertension. This episode of CardioNerds will review the natural history, embryologic origin, diagnostic modalities/findings, indication for closure and long term complications of repaired and unrepaired atrial septal defects. The CardioNerds Adult Congenital Heart Disease (ACHD) series provides a comprehensive curriculum to dive deep into the labyrinthine world of congenital heart disease with the aim of empowering every CardioNerd to help improve the lives of people living with congenital heart disease. This series is multi-institutional collaborative project made possible by contributions of stellar fellow leads and expert faculty from several programs, led by series co-chairs, Dr. Josh Saef, Dr. Agnes Koczo, and Dr. Dan Clark. The CardioNerds Adult Congenital Heart Disease Series is developed in collaboration with the Adult Congenital Heart Association, The CHiP Network, and Heart University. See more Disclosures: None Pearls • Notes • References • Guest Profiles • Production Team CardioNerds Adult Congenital Heart Disease PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Pearls - Atrial Septal Defects It's a CLASSIC! – On physical exam a wide fixed split S2 along with a systolic ejection murmur due to increased blood flow across the pulmonary valve and potentially a diastolic rumble across the tricuspid valve are CLASSIC findings with atrial septal defects. Atrial septal defects are not all the same. There are four types of atrial septal defects: secundum ASD, primum ASD, sinus venosus and coronary sinus defects (NOTE – the latter are atrial level defects which actually do not involve the interatrial septum). The different types warrant a different approach to closure. Use your tools and if your suspicion is high for an atrial septal defect, keep looking. Sinus venosus defects can easily be missed since the superior vena cava is difficult to image in adults. Diagnostic tools include: history and physical exam (USE the stethoscope), ECG, echocardiogram, cardiac MRI, cardiac CT, and cardiac catheterization.Not all defects NEED to be closed immediately. Moderate-large defects with a shunt greater than 1.5:1 should be closed due to increased risk of pulmonary hypertension and arrhythmias, barring contraindications. Surgery was previously the gold standard for closure of ASDs, but many defects especially secundum atrial septal defects are closed in the cath lab. Show notes - Atrial Septal Defects Notes (developed by Dr. Sarah Fahnhorst What are the four different types of atrial level defects?Secundum atrial septal defectMost common type of atrial septal defect (75%)Located in the center of the atrial septum (fossa ovalis)Hole in the primum septum due to deficiency of the septum secundumPrimum atrial septal defectAccounts for 15-20% of ASDLocated at the inferior portion of the atrial septumIn the spectrum of atrioventricular septal defects/endocardial cushion defectsDefect in the developme...
On this special episode, Grant Gottgetreu returns to the podcast discussing the current state of the ASDs and IRPs in BC. Kyla and Paul also look at how a breach of privacy affected an impaired driving case in Yukon. Follow Kyla Lee on Twitter: twitter.com/IRPlawyer Follow Kyla Lee on Instagram: instagram.com/kylaleelawyer www.vancouvercriminallaw.com
Tonight at 8:30 pm CST, on the Flyover Conservatives show we are tackling the most important things going on RIGHT NOW from a Conservative Christian perspective! TO WATCH ALL FLYOVER CONSERVATIVES SHOWS -https://banned.video/playlist/61e636f26959067dbbfa11bfDr. Christiane NorthrupWEBSITE: https://www.drnorthrup.com/WEBSITE: https://howbadismybatch.com/WEBSITE: https://mycyclestory.com/For LIFE-SAVING Information about the Vaccine, - Text VAX to 40509 (Message and data rates may apply. Terms/privacy: 40509-info.com)To Schedule A Time To Talk To Dr. Dr. Kirk Elliott Go To ▶ https://flyovergold.com Or Call 720-605-3900 SPONSORS FOR TODAY'S VIDEO► ReAwaken America- text the word EVENTS to 40509(Message and data rates may apply. Terms/privacy: 40509-info.com)► Kirk Elliott PHD - http://FlyoverGold.com ► My Pillow - https://MyPillow.com/Flyover►Z-Stack - https://flyoverhealth.com Own Your Own Business As An Option To Avoid The Jab- http://FlyoverCarpet.com https://TipTopK9.com/Want to help spread the Wake Up • Speak Up • Show Up -https://shop.flyoverconservatives.com/-------------------------------------------Follow our Social Media so we can be best friends
Dr. Christiane NorthrupWEBSITE: https://www.drnorthrup.com/WEBSITE: https://howbadismybatch.com/WEBSITE: https://mycyclestory.com/For LIFE-SAVING Information about the Vaccine, - Text VAX to 40509 (Message and data rates may apply. Terms/privacy: 40509-info.com)TO WATCH ALL FULL INTERVIEWS -https://banned.video/playlist/62706852531c9f4b27c2e6b1SPONSORS FOR TODAY'S VIDEO► ReAwaken America- text the word EVENTS to 40509(Message and data rates may apply. Terms/privacy: 40509-info.com)► Kirk Elliott PHD - http://FlyoverGold.com ► My Pillow - https://MyPillow.com/Flyover►Z-Stack - https://flyoverhealth.com Own Your Own Business As An Option To Avoid The Jab- http://FlyoverCarpet.com https://TipTopK9.com/Want to help spread the Wake Up • Speak Up • Show Up -https://shop.flyoverconservatives.com/-------------------------------------------Follow our Social Media so we can be best friends
Wish you knew more about different ethnic hairstyling practices? We can help with that. This week, we're joined by Dr. DiAnne Davis as she offers some tips on how to navigate hairstyles that may be less familiar. Listen in for recommendations on patient assessment as well as integrative treatments for tightly curled hair. DiAnne S. Davis, MD is a board-certified cosmetic dermatologist specializing in noninvasive facial rejuvenation, skin of color, hair loss, and cosmetic dermatologic surgery. Dr. Davis completed her baccalaureate studies at Tuskegee University in Tuskegee, AL, graduating Summa Cum Laude with a degree in Biology. She obtained a Master's of Science in Cell & Molecular Biology from Tulane University. She then received her medical degree from The George Washington University School of Medicine and Health Sciences in Washington, DC along with the Walter F. Rosen Award for Outstanding Student in Dermatology. Dr. Davis completed her dermatology residency at the University of Oklahoma Health Sciences Center where she was chief resident her senior year of residency training. While in residency Dr. Davis was influential in coordinating the first Skin of Color Symposium helping to promote awareness of the unique features of skin of color from both a medical and cosmetic dermatologic viewpoint. She has authored several journal articles and textbook chapters (both for medical and cosmetic dermatology) and presented some of her work at local and regional dermatology meetings. She is also the Co-Founder of Sunblock Kids which helps to bring awareness about the importance of sun protection at an early age. Dr. Davis is fellowship-trained in cosmetic dermatology and laser surgery. She completed an ASDS-accredited fellowship program under the directorship of Dr. Mark B. Taylor at the Gateway Aesthetic Institute and Laser Center in Salt Lake City, UT. Working with over 70 lasers, Dr. Davis has expertise in laser skin resurfacing, body contouring, and laser blepharoplasties. Dr. Davis is a member of the American Academy of Dermatology (AAD), American Society for Dermatologic Surgeons (ASDS), the American Society for Laser Medicine and Surgery (ASLMS), the Women's Dermatologic Society (WDS), Skin of Color Society, and the Texas Medical Association. Dr. Davis has served as the resident liaison for ASDS, a member of the curriculum task force for the AAD and has received scholarships for mentorship opportunities through the ASDS. She is the daughter of the late Fred Davis, Jr and Sherill Davis and a proud native of Oklahoma City, Oklahoma. Her interests outside of medicine include hot yoga and dancing, and she was previously an NFL cheerleader for the New Orleans Saints football team. She enjoys international travel, trying new cuisines, and spending time with her family and friends. To learn more about ethnic hair care, attend Dr. Davis' lecture at the 2022 Integrative Dermatology Symposium. Each Thursday, join Dr. Raja and Dr. Hadar, board certified dermatologists, as they share the latest evidence based research in integrative dermatology. For access to CE/CME courses, become a member at LearnSkin.com.
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.09.01.506213v1?rss=1 Authors: Benitez, J. A. R., Kannan, S., Hastings, W., Parker, B., Willbrand, E., Weiner, K. S. Abstract: Two recent parallel research tracks link tertiary sulcal morphology sulci that emerge last in gestation and continue to develop after birth with functional features of the cerebral cortex and cognition, respectively. The first track identified a relationship between the mid fusiform sulcus (MFS) in ventral temporal cortex (VTC) and cognition in individuals with Autism Spectrum Disorder (ASD). The second track identified a new tertiary sulcus, the inframarginal sulcus (IFRMS), that serves as a tripartite landmark within the posteromedial cortex (PMC). As VTC and PMC are structurally and functionally different in individuals with ASD compared to neurotypical controls (NTs), here, we integrated these two tracks with a twofold approach. First, we tested if there are morphological differences in VTC and PMC sulci between 50 NTs and 50 individuals with ASD. Second, we tested if tertiary sulcal morphology was linked to cognition in ASD individuals. Our twofold approach replicates and extends recent findings in five ways. First, in terms of replication, the standard deviation (STD) of MFS cortical thickness (CT) was increased in ASDs compared to NTs. Second, MFS length was shorter in ASDs compared to NTs. Third, the CT STD effect extended to other VTC and PMC sulci. Fourth, a subset of VTC and PMC morphological features were correlated between regions in ASD. Fifth, IFRMS depth was negatively associated with ADOS GS score. These results empirically support a relationship between later-developing, tertiary sulci and ASD, providing a novel framework to study the relationship between brain structure and cognition in additional neurodevelopmental disorders in future studies. Copy rights belong to original authors. Visit the link for more info Podcast created by PaperPlayer
New neurons can be generated in a dish (amazing in itself), and then these neurons can then be studied to examine how they grow, expand, divide and connect. Using this technology, researchers are finding differences in several cell functions in different forms of autism. These differences are in proliferation, which is an increase in the … Continue reading "The earliest differences across ASDs"
In today's episode, we're talking to Dr. Matthew Lerner about Facilitating Social Connections For & Among Those with Autism Spectrum Disorders. Dr. Lerner is an Associate Professor of Psychology and an Assistant Professor of Psychiatry & Pediatrics at Stony Brook University. His research focuses on understanding mechanisms of and developing interventions for social and emotional functioning (in particular peer relations) among children and adolescents with autism spectrum disorders and ADHD. At Stony Brook, Dr. Lerner is the Lab Director of the Social Competence & Treatment Lab (SCTL), a.k.a. the "Lerner Lab" where he conducts his aforementioned research. Today you will learn: What it means to facilitate Social Connections for & among those with ASDs and why it is important The skills needed to develop social connections How those with ASDs develop those skills and who helps them develop those skills How those with ASDs practice those skills How parents can assist with social connections If teachers should assist with social connections and how Links and Resources: Dr. Lerner's Bio: https://www.stonybrook.edu/commcms/psychology/faculty/faculty_profiles/mlerner The Lerner Lab Website: https://www.lernerlab.com Facebook: https://www.facebook.com/LernerLab/ The Autism Initiative at Stony Brook University Facebook: https://www.facebook.com/AutismSBU/ Instagram: https://www.instagram.com/autismsbu/?hl=en Make sure to subscribe and follow us on social media so you never miss an episode! Website: http://www.readingllcenter.com Facebook: http://www.facebook.com/readingllcenter Instagram: http://www.instagram.com/readingllcenter Youtube: https://www.youtube.com/channel/UCWlbl8Ea8DJFADaNU9ZK1Vw LinkedIn: https://www.linkedin.com/company/the-reading-and-language-learning-center
Photo credit: Joe Loong One of the things I've been trying to get across to people for years is the understanding that Applied Behavioral Analysis (ABA) is a science, not a special education service, much less a service specifically for students with Autism Spectrum Disorders (ASDs). The confusion arises from the fact that instructional strategies and behavioral interventions based on the principles of ABA, which work with all learners, just so happen to also work for students with ASDs and often it's the only approach that does. As such, the demand for ABA-based programs for students with ASDs, and the peer-reviewed research around its efficacy with this particular population, has resulted in confusion among the lay public as to what ABA actually is. Because so many people in public education and the families that rely on it only see ABA used with respect to ASDs, they think that's all it's for, and this is a gross failure on the part of the professionals who know otherwise to set things straight. This is why I've been trying to get this point across for so long. Knowledge powers solutions for parents, which is the whole reason our organization exists. The absence of relevant knowledge on behalf of any of the stakeholders in the IEP process can prevent students with disabilities from getting the kinds of help they actually need, so a failure to appreciate that ABA applies to anyone or anything that behaves can have dire consequences for students who would benefit from ABA-based interventions, even if they have conditions other than ASDs that create these needs. That's a whole conversation unto itself, but that's not the focus of this post. Because ABA applies to anyone and anything that behaves, it therefore applies to all the members of a student's IEP team. For parents, the science of ABA can be not only constructive with respect to developing an appropriate IEP for their children, but also in navigating the behaviors of the other IEP team members during IEP meetings and related exchanges with public education agency personnel, which is what I'm focusing on in this post. To be clear, ABA is not a method or strategy. It is a way of describing behaviors according to how they naturally occur. When it is used to make something happen, it's all about how to interact with others in a way that promotes the behaviors we want to see from them. Used ethically in a team context, it keeps conversations productive and collaborative. However, the proverbial snake oil salesman “selling ice cubes to Eskimos” abuses ABA as part of a con to manipulate people's behaviors for personal gain at other people's expense. The thing to understand is that ABA is a reality-based approach to understanding what is going on and planning what to do about it. It isn't an invention; it's simply a tool that measures what already is. That data can then be used to change how things are. So, it's not like I can give you a checklist of things to do, whether you understand them or not, and you're off and running. You need to understand the underlying science, which I'm going to grossly oversimplify here to make the concepts as digestible as possible. Before I launch into what ABA is, I first have to back up and explain the three key tenets of science. Science relies on: Determinism – an understanding that there is a logical, evidence-based explanation for everything in existence. Empiricism – an understanding that every evidence-based explanation can be described in quantifiable terms using fixed increments of measure. Parsimony – the understanding that the simplest explanation that fits the measured evidence is the correct explanation. That's not an ABA-specific thing. That's how all science works, and ABA is a science. Like a financial audit, science renders reality down into measurable bits that can be analyzed for black-and-white, yes/no answers, regardless of what is being discussed. There is a reason that “accounting” and “accountability” share a common root word. Financial audits examine accounting records for accuracy because those records are supposed to account for where money has gone or will go. For this reason, accounting is actually a science. All other forms of science account for things the same way, measuring what is according to fixed increments of measure and giving us an accounting of what is really going on. Such is the case with ABA. The increase of neo-fascism in America, in which science is frequently denied, is really a rejection of accountability and/or a significant detachment from reality consistent with mental illness. It's about skewing numbers (like the 45th President attempting to offload COVID-infected cruise ship passengers at the beginning of the pandemic onto Guantánamo Bay so as to prevent the numbers of infection cases in the United States from going up) or otherwise pretending the numbers are untrue (like “The Big Lie” told by the 45th President regarding the vote count in the 2020 Presidential election), so as to avoid being held accountable. Science is all about explaining reality using numbers, which requires the application of mathematics. There's only one right answer to a math calculation. It never ceases to amaze me the number of people who grasp this concept when it comes to money, but not with anything else. These are generally the kinds of people who own profitable businesses and use their money to hire private jets to fly to Washington, DC, so they can attempt to violently overthrow our government because they fear accountability and equate any perceived loss of privilege or unfair advantage with oppression. Oppressed people can't afford private jets, in case you were wondering. These are also the kinds of people who end up in handcuffs over cooking their companies' books, once the accountability finally catches up with them. When you understand science as a form of accounting for anything that exists in numerical terms, just as with money, it isn't possible to take it as an affront to your belief system, unless you believe things – or are trying to convince other people to believe things – that are not true. There is no rule that says we have to like the truth. An intact person will acknowledge an undesired truth and deal with it. A person engaging in disordered thought will attempt to argue against it and assert beliefs unsupported by evidence as fact, thereby confusing opinion with fact and arguing against what they don't want to be true as though it really isn't. As a parent going into the IEP process, you need to stick to the facts. An IEP is all about measurable annual goals that describe what your child is supposed to be taught and how to measure the degree to which your child learns from that instruction. Services are determined on what is necessary to achieve the degree of success targeted by the goals and placement is determined according to what setting(s) are the least segregated from the general education setting in which the services can be delivered such that the goals are met. The entire process hinges on the appropriate application of the relevant sciences. As a parent, know going into the IEP process that it is scientifically driven and, therefore, relies on measurable facts to inform your child's educational planning, plus it must do so according to the rule of law. The whole system was designed with the education agency's accountability to the individual student and the student's family in mind, which is why it boggles my mind every time I encounter anything but that in the IEP process. Specifically with respect to using ABA to navigate the behaviors of the other team members as a parent attempting to exercise your federally protected right to meaningful participation in the IEP process, there are some ABA-specific concepts you first need to understand. The first concept is that of ABC data collection and the second concept is that of reinforcement. ABC data collection is a process used to determine the function(s) of a specific behavior. The “A” stands for “antecedent,” the “B” stands for “behavior,” and the “C” stands for “consequence.” Each of these has a specific operational definition in ABA, and any deviation from their respective definitions means whoever is taking the data is not actually practicing ABA. An antecedent in ABA is whatever happened right before the behavior that triggered it. When you're talking about students, the presentation of a task demand can be the antecedent to a challenging behavior being addressed by an IEP, for example. When you're talking about corrupt and/or incompetent public agency officials in an IEP meeting, the presentation of a parent request could be the antecedent to some kind of challenging behavior displayed by educational agency personnel, as another example. The behavior in the ABC data collection process is the actual observable behavior being addressed. In the example involving a student just given, let's say the challenging student behavior upon the presentation of a task demand involving a worksheet, is verbal aggression while tearing up the worksheet. In the example of a difficult IEP team member, let's say the challenging behavior upon the presentation of a parent request is a bunch of hyperbolic excuse-making and changing the subject. The consequence in ABA data collection is the immediate outcome produced by the behavior, specifically the pay-off the individual gets by engaging in it. This is an important distinction because it is often inaccurately reported in school-based behavior assessments, where the previous century of relying on a punishment model of behavioral intervention regards “consequence” as something meted out by staff. That is wholly inaccurate. Anything the staff does in response to the behavior, whether it works or not, is a “reactive strategy,” not a “consequence” within the meaning of ABA. The point of identifying the actual consequence achieved by engaging in the behavior is to determine the function served by the behavior for the individual engaging in it. Once the function of the behavior is understood, you can choose how you want to respond to it in a constructive way. When you don't know the actual function of someone else's behavior, you can respond to it in a way that hurts more than helps the situation. Identifying the function of an inappropriate behavior is entirely necessary before an evidence-based approach can be developed to address it. So, using the examples I just gave, let's say that the consequence of the student engaging in verbal aggression and tearing up the worksheet upon the task demand being presented is to escape/avoid the task demand. With respect to an IEP team member engaging in hyperbolic excuse-making and changing the subject when a parent makes a request, the function of the behavior is to escape/avoid addressing, much less honoring, the parent's request. In both of these examples, the function of each of the hypothetical behaviors described were both escape/avoidance, but this is not the only function a behavior can serve. Behaviors happen for only one of two reasons: to get something or get away from something. As such, behaviors can be reduced to a one or a zero, depending on whether its function was to get something (1) or escape something (0). Even the most complex behaviors can thus be reduced down to simple binary code as the most parsimonious way to describe what is happening. In ABA, the functions of a behavior are typically described as access/attainment, escape/avoidance, and automatic. Automatic reinforcement speaks to behaviors that address internal drive states, such as physical wellness and emotionality, but even those are based on access/attainment or escape/avoidance. Sensory-seeking and/or sensory-avoidant behaviors are based on automatic reinforcement for someone with sensory processing issues based on their unique neurology, for example. That leads us to the second key concept of ABA that you need to understand, which is that of reinforcement. A reinforcer is anything that increases the likelihood of an individual engaging in a specific behavior in response to a specific antecedent. If the consequence of the behavior is reinforcing, the individual will continue to engage in it whenever that specific antecedent is presented in order to achieve the reinforcer. For example, if you get hungry (antecedent) and go put money in a vending machine and push the right buttons (behavior), you will get food (consequence). The function of the behavior is access/attainment of food to satisfy your hunger. It's pretty simple. Reinforcement can be positive or negative, but these are not judgments of “good” or “bad.” Just as with magnets, the poles of the Earth, and batteries, the terms “positive” and “negative” have specific meanings within ABA that are also frequently misunderstood in special education behavioral interventions. In reality, when it comes to ABA, “positive” means “to present” and “negative” means “to withdraw.” Positive reinforcement, therefore, is the presentation of something that is likely to reinforce a specific behavior. Negative reinforcement is the removal of something unwanted in order to reinforce a particular behavior. The aforementioned vending machine scenario gives an example of positive reinforcement because food is presented in response to the behavior of putting money into the vending machine and pushing its buttons. Both forms of reinforcement were best explained scientifically back in the early days of behaviorism by B.F. Skinner using what came to be referred to as a “Skinner Box.” In Skinner's positive reinforcement experiments, rats in a cage were taught to pull a lever in order to access food pellets. At first, pulling on the lever was accidental, but as soon as food came out, the rats quickly learned that engaging in the behavior of pulling the lever resulted in the presentation of a food pellet. The presentation of the food pellet reinforced the pulling of the lever. In Skinner's negative reinforcement experiments, rats in a cage with an electrified floor that delivered mild shocks to their feet learned to pull a lever in order to turn off the electrification of the floor. Again, at first, pulling the lever was accidental, but as soon as their feet were no longer getting zapped, the rats quickly learned that engaging in the behavior of pulling the lever resulted in the termination of discomfort caused by the electrified floor of the cage. The removal of the electrification reinforced the pulling of the lever. In both cases, the behavior of pulling the lever was reinforced. It's just that one form of reinforcement provided access to something preferred and the other removed something aversive. Again, this can all be reduced to getting something (1) or getting away from something (0). In the IEP process, you're either getting what you want for your child or you are not. The public education agency personnel are either satisfying their agency's agenda or they are not. The whole situation is riddled with ones and zeros depending on what you are talking about and who is involved. Again, this is all a gross over-simplification of these basic ABA concepts. There are other considerations that have to be taken into account, such as setting events, otherwise known as Motivating Operations (MOs). MOs increase the likelihood of a specific antecedent triggering a specific behavior. In our previous example regarding the student becoming verbally aggressive and tearing up a worksheet upon the task demand being presented, it could be the case that the student normally complied with task demands but, that particular day, the student had a stomach ache and didn't have the concentration and stamina to engage in the task when it was presented. As such, the antecedent was still the presentation of a task demand, but that antecedent occurred in the presence of the MO of a stomach ache, and the consequence was still to escape/avoid the task demand. Similarly, in our example previously regarding education agency personnel engaging in hyperbolic excuse-making and changing the subject in response to a parent request for something, it could be the case that said personnel would have normally agreed to honor the parent's request, but that morning there had been an agency budget meeting in which personnel were told they would be subject to disciplinary action from the agency if they committed the agency to services for students that cost more than a certain amount, which is illegal but nonetheless happens all the time. As such, the antecedent was still the parent request, but it occurred in the presence of the MO of a threat of disciplinary action against agency personnel for committing the agency to costs it didn't want to have to bear, and the consequence was still to escape/avoid honoring the parent's request. Sometimes you don't know what all the MOs are because the education agency personnel won't make them known to you. In many instances, the only way you know something is wrong is because the presentation of an antecedent results in a behavior that produces a consequence that doesn't fit what should be happening. In that case, you know something is wrong because the behavior doesn't fit the situation, at which point you have to ask yourself, “What is the function of this behavior?” It's pretty obvious that any “no” response you receive is an escape/avoidance behavior; it's just sometimes hard to know whether what is being avoided is cost, accountability, or both. For example, data collection practices in special education throughout the country are generally pretty unscientific and shoddy in spite of a federal mandate that special education be delivered according to the peer-reviewed research, which is all scientific, according to measurable annual goals. As black-and-white as the process is supposed to be, it often isn't because school personnel 1) have no idea how to do it correctly, and/or 2) are attempting to avoid accountability. In most cases, it's been my observation that the initial inappropriate behaviors are a consequence of incompetence, which creates a need to pursue accountability, at which point they engage in cover-ups to try to avoid getting into trouble for the errors of their ineptitude. You have to assume as a parent going in that not everybody on your IEP team knows everything they should and that they may respond unethically when they get called out on their errors. In other situations, public education agency personnel are just grifting the system for a government paycheck at taxpayer expense from the outset and see students as a means to their own financial ends, engaging in cover-ups when their self-serving behaviors become exposed. As a parent going into the IEP process, you have to be a shrewd negotiator. If you don't understand the functions of the behaviors of the other IEP team members, you are at risk of being robbed blind by unethical public servants and/or otherwise getting a poorly developed IEP from inept public servants. It's not on you to know all of the science and law that applies to your child's situation, but if you can develop your skills at reading the behaviors of the other IEP team members, you can often figure out whether they are acting according to your child's actual needs or not. At that point, how you respond becomes the next hurdle to clear. Every situation requires its own analysis and there is no way I can give you a one-size-fits-all solution, here. What I can tell you to do is pay attention, try to get a sense of the function of someone's inappropriate behavior as best as possible, and offer reinforcers in order to achieve the behaviors you want to see. For example, send a thank-you card to the school psychologist who actually threw down on an excellent report and you will positively reinforce legally compliant behavior. Or, withdraw a compliance complaint if the agency remedies the problem that compelled you to file it and you will negatively reinforce legally compliant behavior. They can earn a food pellet or stop their feet from getting zapped, metaphorically speaking, but, either way, they're going to have to pull the lever. If you can keep these concepts straight, you will be in a much better position to effectively participate in the IEP process.
Chef Jacqueline Myer of Broth and Brine, a new restaurant in the Houston area joins me today to discuss her path to the culinary arts, her hot take on food as medicine, and much more.Jacqueline Myers is chef-owner of Broth & Brine | Dedicated Craft Kitchen as well as GF Personal Chef | Gluten Free & Paleo. In addition to her role as chef-owner-manager at Broth & Brine, she is also a personal chef and a food and wellness consultant. She intercedes for clients on their healing journeys using a food-as-medicine approach.Jacqueline holds a Master of Science degree in secondary education from Indiana University, as well as a Bachelor of Arts degree in Journalism and Spanish. She has always held a passion for the culinary world, cooking, and world travel. Through food, perspective is downloaded and peoples are united. Having spent 16 years as an educator, Jacqueline observed the rise of gut-related disorders and astonishing epidemic of ASD—Autism Spectrum Disorders. Through a series of events, she began to investigate the root cause(s) of ASDs, the brain connection, and the factors involved in other autoimmune conditions including cancer and diabetes. Toxicity and gut health emerged as critical factors in need of immediate attention across all United States demographics. For Jacqueline, it was time to step out of a classroom with four walls and take action at a different level in order to encourage change and healing for our children and our society.Combining her passion for research, education, and food preparation, Jacqueline embarked on a relevant and timely mission to help others using the timeless concept of nutrition. She relied on her time spent studying and traveling abroad, as well as her passion for healing foods of the Mediterranean and our distant ancestors.At the core of her mission today is to empower others with knowledge and skills for healing true root imbalances using food as a first line intervention and prevention.To learn more about today's guest, please check out her websites below.Broth and BrineGF Personal ChefTo learn more about the wonderful Dachshund Rescue of Houston, including adoption, their foster program, or making a donation, check out droh.orgTo connect with the Tammy and learn more about the podcast, as well as hearing from other creative guests in the blog, check out the websites and links below.Webpage: https://tstakaishi.wixsite.com/musicIG: https://www.instagram.com/creative_peacemeal_podcast/?hl=en Facebook: https://www.facebook.com/creativepeacemealpod/
Dr. Murad Alam, professor of dermatology and chief of cutaneous and aesthetic surgery in the department of dermatology at Northwestern University, Chicago, discusses recently released evidence-based recommendations on preventing and treating adverse events from injectable fillers. A recent paper outlines recommendations from an American Society for Dermatologic Surgery (ASDS) multidisciplinary task force. The paper was published in the February issue of Dermatologic Surgery (Dermatol Surg. 2021 Feb 1;47(2):214-26). Dr. Alam also provides an overview of a new patient safety database – the Cutaneous Procedures Adverse Events Reporting (CAPER) system -- a collaboration between Northwestern’s department of dermatology and the ASDS Association (ASDSA). Dr. Alam is a past ASDS president and current chair of the ASDSA’s Federal Affairs Work Group. He had no disclosures. References: ASDS issues first filler safety recommendations Dermatologic surgeons debut adverse event reporting database * * * You can find more of our podcasts at: http://www.mdedge.com/podcasts Email the show: podcasts@mdedge.com Interact with us on Twitter: @MDedgeDerm
Sleep is a huge problem in ASD. But is it just “sleep” or can we get more specific? What role do genetics have? And does being autistic make sleep problems worse? Answers come from an unlikely source: mice! Learn more about recent scientific evidence tying sleep problems to ASDs and neurodevelopmental disorders. These include: type […]
Dr. Peter GerhardtIn this podcast we talk about transition planning during COVID with Dr. Gerhardt. Dr. Gerhardt is the Executive Director of EPIC School in Paramus, NJ. He has more than 30 years experience utilizing the principles of Applied Behavior Analysis in support of individuals with autism spectrum disorders in educational, employment, residential and community-based settings. Dr. Gerhardt is the author or the coauthor of many articles and book chapters on the needs of adolescents and adults with ASDs and has presented nationally and internationally on this topic. Dr. Gerhardt is the founding chair of the Scientific Council for the Organization for Autism Research (OAR) and currently sits on numerous professional advisory boards including Behavior Analysis in Practice, the Cambridge Center for Behavioral Studies, the Association of Professional Behavior Analysts, and the Autism Society of America. He received his doctorate from Rutgers, the State University of New Jersey, Graduate School of Education.
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.11.04.367821v1?rss=1 Authors: Jha, U., Kondrychyn, I., Korzh, V., Thirumalai, V. Abstract: Autism spectrum disorders (ASDs) are characterized by abnormal behavioral traits arising from neural circuit dysfunction. While a number of genes have been implicated in ASDs, in most cases, a clear understanding of how mutations in these genes lead to circuit dysfunction and behavioral abnormality is absent. The autism susceptibility candidate 2 (AUTS2) gene is one such gene, associated with ASDs, intellectual disability and a range of other neurodevelopmental conditions. Yet, the function of AUTS2 in neural development and circuit function is not at all known. Here, we undertook functional analysis of Auts2a, the main homolog of AUTS2 in zebrafish, in the context of the escape behavior. Escape behavior in wild type zebrafish is critical for survival and is therefore, reliable, rapid, and has well-defined kinematic properties. Auts2a-/- zebrafish are viable, have normal gross morphology and can generate escape behavior with normal kinematics. However, the behavior is unreliable and delayed, with high trial-to-trial variability in the latency. We demonstrate that this is due to the reduced excitability of Mauthner neurons resulting in unreliable firing with stimuli that normally elicit the escape response. Combined with previous studies that show Auts2-regulation of the transcription of ion channel proteins, our results suggest that Auts2 sets the excitability of neurons by activating a set transcriptional program. Copy rights belong to original authors. Visit the link for more info
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.10.14.339291v1?rss=1 Authors: Massaccesi, C., Groessing, A., Rosenberger, L. A., Hartmann, H., Candini, M., di Pellegrino, G., Frassinetti, F., Silani, G. Abstract: Interpersonal space can be defined as a safety zone immediately surrounding our body, which allows us to feel comfortable during social interactions. Previous studies indicate that the size of interpersonal space at which the other is perceived as intrusive (permeability) and the ability to adapt interpersonal distance based on contextual factors (flexibility) are altered in children and adults with Autism Spectrum Disorder (ASD). The present fMRI study aimed at extending the previous findings by investigating the behavioral and neurophysiological underpinnings of interpersonal space permeability and flexibility in adults with ASD. Individuals with ASD and matched controls (CTR) performed a modified version of the stop-distance paradigm for measuring interpersonal space preferences. Participants observed prerecorded videos of two confederates moving towards them and rated their comfort to the observed distance. The assessment of interpersonal space preferences was performed before and after engaging in cooperative and non-cooperative social interactions with the confederates, experimentally induced by means of a repeated trust game. We observed general lower comfort in response to an approaching confederate in the ASD group compared to the CTR group, indicating preference for larger interpersonal space in autism (altered permeability). This preference was accompanied by reduced activity in bilateral dorsal intraparietal sulcus (dIPS) and left fusiform face area (FFA), regions previously shown to be involved in interpersonal space regulation. Furthermore, we observed differences in effective connectivity among dIPS, FFA, and amygdala in ASDs compared to CTRs, depending on the level of experienced comfort. No differences between ASDs and CTRs were observed in the adaptation of interpersonal space following a cooperative and non-cooperative social interaction, suggesting preserved interpersonal space flexibility in the ASD adult population. The present study provides evidence for impaired permeability of interpersonal space in adults with ASD. The findings suggest that a dysregulation of the activity and connectivity of brain areas involved in the processing of interpersonal space may contribute to preference for larger distance and avoidance of physical proximity in ASDs. Future research is needed to examine whether the observed alteration of interpersonal space processing is an effect of or a contributing factor to the social disabilities characterizing autism. Copy rights belong to original authors. Visit the link for more info
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.09.14.290106v1?rss=1 Authors: Kojovic, N., Franchini, M., Sandini, C., Sperdin, H. F., Jan, R. K., Zoeller, D., Schaer, M. Abstract: Atypical deployment of social gaze is present early on in toddlers with autism spectrum disorders (ASDs). Yet, studies characterizing the developmental dynamic behind it are scarce. Here we used a data-driven method to delineate the developmental change in visual exploration of social interaction over childhood years in autism. Longitudinal eye-tracking data were acquired as children with ASD and their typically developing (TD) peers freely explored complex animated scene. We found divergent moment-to moment gaze patterns in children with ASD compared to their TD peers. This divergence was particularly evident in sequences that displayed social interactions between characters, and even more so in the children with lower developmental and functional levels. Basic visual properties of the animated scene did not accounted for the enhanced divergence. Over childhood years, these differences dramatically increased to become more idiosyncratic. Taken together, these findings suggest that social attention should be targeted early in clinical treatments. Copy rights belong to original authors. Visit the link for more info
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.08.27.267880v1?rss=1 Authors: Anstey, N. J., Kapgal, V., Tiwari, S., Watson, T. C., Toft, A. K., Dando, O. R., Inkpen, F. H., Baxter, P. S., Kozic, Z., Jackson, A. D., He, X., Nawaz, M. S., Kayenaat, A., Bhattacharya, A., Wyllie, D. J., Chattarji, S., Wood, E. R., Hardt, O., Kind, P. C. Abstract: Mutations in the postsynaptic transmembrane protein neuroligin-3 are highly correlative with autism spectrum disorders (ASDs) and intellectual disabilities (IDs). Fear learning is well studied in models of these disorders, however differences in fear response behaviours are often overlooked. Whilst examining fear in a rat model of ASD/ID lacking Nlgn3, we observed that they display a greater propensity to exhibit flight responses in contrast to classic freezing seen in wildtypes during fearful situations. Consequently, we examined the physiological underpinnings of this in neurons of the periaqueductal grey (PAG), a midbrain area involved in flight-or-freeze responses. In ex vivo slices from Nlgn3-/y rats, dorsal PAG (dPAG) neurons showed intrinsic hyperexcitability. Further analysis of this revealed lower magnitude in vivo dPAG stimulation evoked flight behaviour in Nlgn3-/y rats, indicating the functional impact of the increased cellular excitability. This study provides new insight into potential pathophysiologies leading to emotional disorders in individuals with ASD. Copy rights belong to original authors. Visit the link for more info
Bei den Border Collies wird in der Zucht bzw. Zuchtausrichtung zwischen Showlinie und Arbeitslinie unterschieden. Im Gespräch mit Barbara Weinrauch gehen wir der Arbeitslinie auf den Grund. Barbara erklärt unter anderem Folgendes: Was ist Arbeitslinie? Welche Veranlagungen hat der Border Collie der Arbeitslinie? Was unterscheidet den Border Collie der Arbeitslinie von anderen Hütehunden? Was ist der Unterschied zwischen Showlinie und Arbeitslinie? Wie komplex ist die Zucht des Border Collies? Ist das Hüteverhalten ein Jagdverhalten? Was bedeutet ASDS, ISDS, FCI? Nach welchen Zielen und Standards wird gezüchtet? Muss ein Border Collie der Arbeitslinie am Schaf arbeiten? Was macht ein Border Collie der Arbeitslinie wenn er nicht an Schafen arbeitet? Wie muss ein Border Collie der Arbeitslinie geführt werden? Beim Trial Sport werden die Border Collies der Arbeitslinie in der Zusammenarbeit mit dem "Handler" in einem Bewerb in der Arbeitsfähigkeit an Schafen bewertet. Was ist Trial und wie funktioniert es? Ist es ratsam mit einem BC der Arbeitslinie nur Trial zu machen ohne Arbeit am Schaf? Wie erfolgt die Kommunikation zum Border Collie? Wie lange dauert es bis ein Border Collie der Arbeitslinie ausgebildet ist? Welche Überlegungen sollte man sich vor Anschaffung eines Border Collies stellen? Welchen Menschen ist davon abzuraten einen Border Collie zu nehmen? Was hat dir Dein Border Collie gelernt? Was ist ein guter Hundezüchter? Welche Buchempfehlung hast Du zum Thema Border Collies? Barbara Weinrauch (Feldbach, Österreich) "Schafe, Hunde und Sheepdog Trials sind meine große Leidenschaft" Barbara züchtet Border Collies der Arbeitslinie und hat Österreich mehrmals bei Europameisterschaften im Sheepdog Trial Sport vertreten. Für 2020 konnte sie sich mit Ihren Hunden für die Weltmeisterschaft qualifizieren. Sie ist im Vorstand der ASDS (Austrian Sheepdog Society) und zuständig für die Zuchtabwicklung. www.styrianheart.at www.asds.at Facebook: https://www.facebook.com/barbara.weinrauch Links Buchempfehlungen: https://amzn.to/2DxwU92 https://amzn.to/2XGGux3 +++++++++++++++++++++++ +++++++++++++++++++++++
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.08.03.233437v1?rss=1 Authors: Shihao, W., Xiao, L., Dongdong, Q., Linheng, Z., Tian-Lin, C., Zhifang, C., Binbin, N., Xiaofeng, R., Jing, W., Wenchao, W., Yingzhou, H., Yilin, G., Longbao, L., Yong, Y., Xintian, H., Zilong, Q. Abstract: Although CRISPR/Cas9 mediated gene editing is widely applied to mimic human disorders, whether acute manipulation of disease causing genes in the brain leads to behavioral abnormalities in non human primates remains to be determined. Here we induced genetic mutations in MECP2, a critical gene linked to Rett syndrome (RTT) and autism spectrum disorders (ASDs), in the hippocampus (DG and CA1~4) of adolescent rhesus monkeys (Macaca mulatta) in vivo via adeno associated virus (AAV) delivered Staphylococcus aureus Cas9 with sgRNAs targeting MECP2. In comparison to monkeys injected with AAV-SaCas9 alone (n = 4), numerous autistic-like behavioral abnormalities were identified in the AAV~SaCas9~sgMECP2 injected monkeys (n = 7), including social interaction deficits, abnormal sleep patterns, insensitivity to aversive stimuli, abnormal hand motions and defective social reward behaviors. Furthermore, some aspects of ASDs and RTT, such as stereotypic behaviors, did not appear in the MECP2 gene-edited monkeys, suggesting that different brain areas likely contribute to distinct ASD symptoms. This study showed that acute manipulation of disease-causing genes via in vivo gene editing directly led to behavioral changes in adolescent primates, paving the way for the rapid generation of genetically engineered non-human primate models for neurobiological studies and therapeutic development. Copy rights belong to original authors. Visit the link for more info
Welcome to the 1st episode of Two Legit to QT with Quoia and Tish. BFFs, Actresses and Entreprenuers d'Arquoia Connor and Artisha Mann-Cooper discuss how to make a change in instuitional racism and how allies can help. Special guest Yha Mourhia Wright, Kari Hinkson, Kaili Turner and Javana Mundy.
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.06.29.178350v1?rss=1 Authors: Bian, W.-J., de Lecea, L. Abstract: Sleep takes one-third of our lives, yet its functions remain largely unknown. A large proportion of young patients with neurodevelopmental disorders such as autism spectrum disorders (ASDs) and schizophrenia have sleep problems, including delayed sleep onset, shortened sleep duration and sleep fragmentation, which have been linked to social interaction deficit, a shared symptom of these disorders. However, the causal relationship between sleep disruption and social defects as well as the underlying mechanisms have not yet been established despite its importance in understanding the etiology of these disorders and developing potential therapeutic means. Here using the three-chamber social interaction test, we found that developmental sleep disruption (SD) in adolescent mice caused significant and long-lasting impairment in the preference towards social novelty during adult social interactions without affecting the overall sociality. Interestingly, SD performed in the adulthood did not induce any social defect, indicating a critical period within adolescence during which sleep shapes social novelty preference. Furthermore, by analyzing the adolescent sleep and adult social behavior in a mouse model of Shank3 mutation that mimics a genetic aberrance in ASDs, we found that the development of sociality is correlated with adolescent NREM sleep while social novelty preference is correlated with adolescent REM sleep. Collectively, these results demonstrate a critical role of adolescent sleep in the forming of social novelty preference and the developmental shaping of social behavior. Copy rights belong to original authors. Visit the link for more info
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.06.11.147231v1?rss=1 Authors: Grossman, Y. S., Fillinger, C., Manganaro, A., Voren, G., Waldman, R., Zou, T., Jannsen, W., Kenny, P., Dumitriu, D. Abstract: Background: Depression is a debilitating neuropsychiatric disorder with 20% lifetime prevalence in the developed world but only approximately half of afflicted individuals respond to currently available therapies. While there is growing understanding of the neurobiological underpinnings of the depressed brain, much less is known about the preexisting circuitry leading to selective vulnerability versus resilience. Elucidating these networks could lead to novel preventative approaches. Methods: We developed a model of acute social defeat stress (ASDS) that allows classification of male mice into "susceptible" (socially avoidant) versus "resilient" (expressing control-level social approach) one hour after exposure to six minutes of social stress. Using circuit tracing and high-resolution confocal imaging, we explored differences in activation and dendritic spine density and morphology in the prelimbic to basolateral amygdala (PL[->]BLA) circuit in resilient versus susceptible mice. To test the functional relevance of identified structure/function differences to divergent behavioral responses, we used an intersectional chemogenetic approach to inhibit the PL[->]BLA circuit during or prior to ASDS. Results: Susceptible mice had greater PL[->]BLA recruitment during ASDS and activated PL[->]BLA neurons from susceptible mice had more and larger mushroom spines compared to resilient mice. Inhibition of the PL[->]BLA circuit led to a population shift towards resilience. Conclusion: Preexisting PL[->]BLA structure/function differences mediate divergent behavioral responses to ASDS in male mice. These results support the PL[->]BLA circuit as a biomarker of trait vulnerability and potential target for prevention of stress-induced psychopathology. Copy rights belong to original authors. Visit the link for more info
Thank you to the American Academy of Pediatrics for publishing an updated guide for their 67,000 members about identification, evaluation and management of children on the autism spectrum. Pediatricians have a lot of things going on every day and could use a primer, or a condensed guide, on what the basic level of care should […]
In this episode I visit with Dr. Amber Khanna of the University of Colorado about some of the “simple” congenital heart defects. We discuss atrial septal defects (ASD) and ventricular septal defect (VSD). We review useful testing to diagnose and evaluate these defects and the indications for closure. Links: 2018 ACC/AHA Guidelines for the Management … Continue reading ASDs and VSDs with Amber Khanna →
Themen heute: Toyota intensiviert Partnerschaft mit Fahrdienstanbieter Grab /// Faurecia - Innovativster Automobilzulieferer 2018 1.Die Toyota Motor Corporation (TMC) und der Mobilitäts-Dienstleister Grab Holdings Inc. intensivieren ihre bestehende Partnerschaft und weiten ihre Zusammenarbeit in Südostasien aus. Dazu investiert Toyota unter anderem eine Milliarde US-Dollar in das Partnerunternehmen. Grab betreibt mobile Plattformen für allgemeine Transportdienstleistung, Essens- und Paketdienste, mobile Bezahldienste und Finanzservices in 217 Städten in acht Ländern Südostasiens. Im März dieses Jahres hat Grab das Südostasiengeschäft von Uber übernommen und ist damit der führende Fahrdienstanbieter in dieser Region. Die beiden Unternehmen entwickeln seit August 2017 vernetzte Services und nutzen dafür Fahrdaten, die mit dem Toyota TransLog Fahrtenschreiber gesammelt werden. Der vom Autohersteller für Unternehmensflotten entwickelte Rekorder befindet sich in 100 Mietfahrzeugen von Grab. Die gesammelten Daten werden auf der Toyota Mobilitätsplattform gespeichert, die als eine Art Informations-Infrastruktur für vernetzte Fahrzeuge dient. Aktuell bieten beide Unternehmen auf Basis gesammelter Fahrdaten beispielsweise Versicherungen für die Mietwagenflotte in Singapur an. Die jetzt angekündigte Ausweitung der Zusammenarbeit betrifft die Vernetzung der Mietwagenflotte von Grab in ganz Südostasien sowie die Einführung verschiedener vernetzter Dienste, die die in der Toyota Plattform gespeicherten Daten nutzen. Geplant sind außerdem Versicherungsangebote auf Basis von Fahrdaten, Finanzdienstleistungen und Wartungsdienste. 2. Faurecia, eines der global führenden Technologieunternehmen in der Automobilbranche, wurde in der vergangenen Woche mit dem AutomotiveINNOVATIONS Award als „Innovationsstärkster Automobilzulieferer 2018“ in der Kategorie „Antrieb“ ausgezeichnet. Prämiert wurde das Unternehmen für seine ASDS™-Nachrüstlösung für bestehende Dieselfahrzeuge. ASDS™ ist eine richtungweisende Lösung, die von Amminex, einer Tochtergesellschaft von Faurecia, entwickelt wurde. Sie nutzt Ammoniak in gasförmigem Zustand, was eine überdurchschnittliche NOx-Reduktion für Dieselmotoren auch bei kalten und städtischen Fahrbedingungen ermöglicht. ASDS™ ist eine der Technologien, die am besten geeignet ist, um die Einhaltung strengerer Abgasnormen in Zukunft zu gewährleisten. Das von Faurecia vorgestellte System ASDS™ für Pkw ist ein Prototyp. Dabei handelt es sich um eine verkleinerte Version der bereits in der Serienproduktion befindlichen Nachrüstlösung für Busse und Lkw. Diesen Beitrag können Sie nachhören oder downloaden unter:
Daniel Sansing is a husband, father, and college instructor. He has also worked as a reporter. Daniel is also autistic, and in this episode, he offers insights from his experiences with other diagnoses and finally obtaining the autism diagnosis. Daniel's children and his wife are neurodiverse. Media accounts overlook neurodiverse parents, members of the autistic community I hope to highlight. For transcripts, visit The Autistic Me blog.
Some brief SpaceX history today. I can't believe we are approaching 250 episodes! Friday's podcast is going to be awesome. A Gemini launch and New Horizons don't miss it! Thanks to everyone that's subscribed to the podcast. If you could do me a favor and leave a review for the podcast, I'd appreciate it! If you take a screenshot of your review and send it to @johnmulnix, pretty much anywhere on the Internet, I will send you a Space Shot sticker and a thank you! Connect with me on Facebook, Instagram, and Twitter, just click the links below. Facebook (https://m.facebook.com/thespaceshot/) Instagram (https://www.instagram.com/johnmulnix/) Twitter (https://twitter.com/johnmulnix) Episode Links: Jason-3 NASA JPL (https://sealevel.jpl.nasa.gov/missions/jason3/) Falcon 9 launches Jason-3 satellite but landing attempt fails- SpaceNews.com, Jeff Foust (http://spacenews.com/falcon-9-launches-jason-3-satellite-landing-attempt-fails/) Jason-3 SpaceX Hosted Webcast- YouTube (https://www.youtube.com/watch?v=ivdKRJzl6y0)
Episode Links: The CRS-12 launch is scheduled for 12:31 p.m. EDT on Monday, August 14th. After the launch occurs this link won't show the live feed. SpaceX Webcast (http://www.spacex.com/webcast) One week from now I will be at the Homestead National Monument for the Eclipse! Follow me on Facebook, Instagram, or Twitter. Search @johnmulnix or The Space Shot. Facebook Link (https://www.facebook.com/thespaceshot/) OCISLY- Of Course I Still Love You (https://en.wikipedia.org/wiki/Autonomous_spaceport_drone_ship) JCSAT-16 Mission Overview (http://www.spacex.com/sites/spacex/files/spacex_jcsat16_press_kit.pdf) JCSAT-16 Hosted Webcast (Starts at 20 minutes in) (https://youtu.be/QZTCEO0gvLo?t=20m46s)
According to the CDC, autism spectrum disorders (ASDs) now affect approximately 1 in 88 American children. ASDs can have lifelong effects on individual functioning in areas such as learning, relationships, and independence in daily life. In this segment, John Constantino, MD, Washington University pediatric psychiatrist at St. Louis Children’s Hospital, discusses the importance of a comprehensive assessment for intervention planning—and describes the next steps in the intervention process including development and implementation of an intervention plan. According to the CDC, autism spectrum disorders (ASDs) now affect approximately 1 in 88 American children. ASDs can have lifelong effects on individual functioning in areas such as learning, relationships, and independence in daily life. In this segment, John Constantino, MD, Washington University pediatric psychiatrist at St. Louis Children’s Hospital, discusses the importance of a comprehensive assessment for intervention planning—and describes the next steps in the intervention process including development and implementation of an intervention plan.
NASA selected six companies, as part of the NextSTEP program, to develop ground prototypes of deep space habitats, and the Centaur could live on as a wet workshop. Orbital ATK pushed OA-5 to late September. SpaceX landed yet another stage on the ASDS, and have up to 9 more launches planned for 2016. NextSTEP Pushes Forward to Ground Prototypes - Main Engine Cut Off NextSTEP Partners Develop Ground Prototypes to Expand our Knowledge of Deep Space Habitats OA-5 Slips to Late September - Main Engine Cut Off OA-5 Mission Page Gwynne Shotwell at SmallSat: First Raptor Shipped to McGregor - Main Engine Cut Off A Look at SpaceX’s Remaining 2016 Manifest - Main Engine Cut Off SpaceX successfully launches JCSat-16 satellite, faces crowded end-year manifest - SpaceNews.com Email feedback to anthony@mainenginecutoff.com Follow @WeHaveMECO Support Main Engine Cut Off on Patreon
Today Show: Healthy Vision and Eyecare - Part 2Guest Speaker: Dr. Marc Grossman http://www.naturaleyecare.com/Healthy Vision is Our Strongest Link to the World Around Us. NaturalEyeCare™ was created in May, 1999 to help health care professionals and the public become aware of the role of complementary care in the treatment of eye disease. We believe that combining the best in traditional and complementary care creates the greatest opportunity for individuals to protect and improve vision. We believe that the health of the eye depends on the well-being of one's entire body. We provide recommendations for healing and preserving vision that encompass lifestyle, diet and nutritional products based on our analysis of peer review studiesHealth News Segment with: Dr. Wald, director of Longevity at Integrated Medicine http://www.blooddetective.com/Today Topic: Part 6 Autism Epidemic/ASD - 6 Part SeriesThe Autism/ASD Epidemic is a profound, eye-opening series of short, informative and practical talks presented by the Dr. Michael Wald - nicknamed the Blood Detective. Dr. Wald explores the criteria for autism and autism spectrum disorders (ASDs), talks about potential causes from all angles and critically evaluates both medical and nutritional and natural treatments.
Today Show: Chiropractic and it’s Health BenefitsGuest Speaker: Dr. Tom McGuire D.C., B.S. http://www.innatelivingcenter.com/index.htmlDr. Tom gets to the heart of the matter by addressing the cause of your problem, not just by treating the symptoms. Using an array of diagnostic tools, we are able pinpoint the sources of injuries or other problematic areas, known as subluxations, that lead to pain or ongoing discomfort.Chiropractic was introduced to Dr. Tom at the age of 19. He suffered from digestive problems from the age of 7, and went to every doctor and specialist imaginable to find the cause of his problem, to no avail. He suffered an array of symptoms throughout his adolescent and teen years.Dr. Tom sought relief by agreeing to visit a chiropractor. After only one week of treatment, his digestive problems subsided, never to return again.Because of Dr. Tom’s personal experience, he found his purpose in life through natural health. He truly understood its benefits, and felt his body functioning better than ever, all because of chiropractic care.Dr. Tom now shares his knowledge and expertise by practicing evidence-based chiropractic care. He utilizes the latest state-of-the-art chiropractic techniques, while providing patients with predictable and reliable results.Health News Segment with: Dr. Wald, director of Longevity at Integrated Medicine http://www.blooddetective.com/Today Topic: Part 5 Autism Epidemic/ASD - 6 Part SeriesThe Autism/ASD Epidemic is a profound, eye-opening series of short, informative and practical talks presented by the Dr. Michael Wald - nicknamed the Blood Detective. Dr. Wald explores the criteria for autism and autism spectrum disorders (ASDs), talks about potential causes from all angles and critically evaluates both medical and nutritional and natural treatments.
Today Show: Financial BreakdownGuest Speaker: Richard MartinNews, Politics, Finance and Events. Richard Martin reviews the up to the minute events shaping your future in policy, economics, and world events like global civil unrest and financial breakdown. The clouds are gathering brutality is everywhere. The alarm bells are actually beginning to be heard. Let see what’s coming – good or bad news!Health News Segment with: Dr. Wald, director of Longevity at Integrated Medicine http://www.blooddetective.com/Today Topic: Part 4 Autism Epidemic/ASD - 6 Part SeriesThe Autism/ASD Epidemic is a profound, eye-opening series of short, informative and practical talks presented by the Dr. Michael Wald - nicknamed the Blood Detective. Dr. Wald explores the criteria for autism and autism spectrum disorders (ASDs), talks about potential causes from all angles and critically evaluates both medical and nutritional and natural treatments.
Today Show: Secure your Policies InformationGuest Speaker: Mary & John Sullivan - Owners http://www.2mypolicies.com/npm/ 2MyPolicies holds your family’s essential insurance information as well as contact information of essential service providers. 2MyPolicies can help keep you organized and simplify all your important documents on every Smart phone in the family. Keep everything in one place that’s easy to use, access and maintain. Great for busy families trying to manage all types of information from various insurance carriers and service providers. And the entire family accesses the information for the same affordable monthly subscription.Using modern technology, Doctors are once again making house calls and at a fraction of the usual cost or typical insurance costs. Now you and your loved ones can have access to a doctor 24 hours a day, 7 days a week. There are no contracts - cancel anytime with unlimited number of calls and unlimited consulting time - unlike Doctor on DemandHealth News Segment with: Dr. Wald, director of Longevity at Integrated Medicine http://www.blooddetective.com/Today Topic: Part 3 Autism Epidemic/ASD - 6 Part SeriesThe Autism/ASD Epidemic is a profound, eye-opening series of short, informative and practical talks presented by the Dr. Michael Wald - nicknamed the Blood Detective. Dr. Wald explores the criteria for autism and autism spectrum disorders (ASDs), talks about potential causes from all angles and critically evaluates both medical and nutritional and natural treatments.
Today Show: Healthy Vision and EyecareGuest Speaker: Dr. Marc Grossman http://www.naturaleyecare.com/Healthy Vision is Our Strongest Link to the World Around Us. NaturalEyeCare™ was created in May, 1999 to help health care professionals and the public become aware of the role of complementary care in the treatment of eye disease. We believe that combining the best in traditional and complementary care creates the greatest opportunity for individuals to protect and improve vision. We believe that the health of the eye depends on the well-being of one's entire body. We provide recommendations for healing and preserving vision that encompass lifestyle, diet and nutritional products based on our analysis of peer review studies.Health News Segment with: Dr. Wald, director of Longevity at Integrated Medicine http://www.blooddetective.com/Today Topic: Part 2 Autism Epidemic/ASD - 6 Part SeriesThe Autism/ASD Epidemic is a profound, eye-opening series of short, informative and practical talks presented by the Dr. Michael Wald - nicknamed the Blood Detective. Dr. Wald explores the criteria for autism and autism spectrum disorders (ASDs), talks about potential causes from all angles and critically evaluates both medical and nutritional and natural treatments.
Today Show: Hotel Md 24/7Guest Speaker: Ken Crause – Owner http://hotelmd247.com/Ken Crause, a world traveler himself, saw a need for easy access to a doctor when traveling around the world and felt that many other travelers would welcome the benefit of conveniently accessing a doctor from the privacy of their hotel room, should they not feel well while staying at a hotel. It was this idea that prompted him to create Hotel 247 MD. His experience in Telemedicine enabled him to adapt the technology specifically for hotels and resortsMembers can access them via toll free phone, smart phone, ipad or computer. A doctor will be in touch with you in an hour or less from the time you call in. You can also book a video appointment online that suits your time schedule, with any of our doctors.Health News Segment with: Dr. Wald, director of Longevity at Integrated Medicine http://www.blooddetective.com/Today Topic: Autism Epidemic/ASD Part 1of 6 Part SeriesThe Autism/ASD Epidemic is a profound, eye-opening series of short, informative and practical talks presented by the Dr. Michael Wald - nicknamed the Blood Detective. Dr. Wald explores the criteria for autism and autism spectrum disorders (ASDs), talks about potential causes from all angles and critically evaluates both medical and nutritional and natural treatments.
Epic Garage Hour: gearhead gifting, speed parts, guns, pterodactyls, political soothsaying, Arnold's 9mm pizza and Italian versus Russian jokes (In ReSoviet Russia, president assasinates you!); just a taste. Tyler and Peter from The Bullet Points join Hostus Maximus Justin Fort and Agent Aya for one of the most thorough, most complete Garage Hours ever put to podcast, and they talk through a host of the fantastic tomfoolery you care about. Black Friday versus your new Tazer? Microdots versus a vacuum? John Paul Jones versus awesomeness? Obamacare versus a kick in the nuts? What about REI and Sierra Nevada versus your trail access rights? Vinyl? Cassettes? White versus dark meat? Ant that's before the Bloody Marys have a chance to kick in. There's also the cornucopia of excellent that would be the Garage Hour's unintended topics: blown MTRs, flimsy atomic super golf carts, wrecked Dregs-class Rangers, Chuck Norris, Jesse "The Body" Ventura, ammo gifting, the UTS-15 failmachine, Tesla versus Edison, modular Mustang parts (P and PE heads, anyone?), the GT-40 at LeMans, one versus two-way slings, and how Metallica helped win the Battle of Athens. So much awesome. Have some.
Kristi Yamaguchi, Olympic Champion “Having achieved my own dreams, I want to give to kids who are less fortunate, who struggle with everyday obstacles. I want to give them something positive in their lives: support.” After winning the gold in women’s singles figure skating in the 1992 Olympics and having an amazing amateur and pro career. Kristi Yamaguchi had lived her dreams. She decided it was time to give back to the world by starting the Always Dream foundation. From the Always Dream website: Our Mission: To inspire underserved children to reach for their dreams through innovative reading programs and by advancing the cause of early childhood literacy. Our Always Reading literacy program combines technology with books to raise literacy skills, increase overall academic success and life potential. We also inspire children to “dream big” through engaging families with community events and serving as an advocate, highlighting the importance of early childhood literacy. I have spoken before of the need for early literacy as a vehicle to success. Instilling a love of reading before the 4th grade is absolutely essential. The skills acquired are used for their entire lifetime and become second nature. After a while they don’t even have to think about it. Looking at something means that it automatically reads for them. Arriving at this level of competence requires some early help from parents and teachers, and also organizations like Always Dream. It is crucial that our next generation learns the skills they need to survive and thrive when they are old enough to be the next leaders. The future, ours and theirs, totally depends on it. We can’t afford to drop the ball on this one. Check out the links to Kristi Yamaguchi and her great organization. They will be included in the show notes for this episode at Daggers Of The Mind.com. St. Francis of Assisi “For it is in giving that we receive.” http://kristiyamaguchi.com/ https://www.alwaysdream.org/ Kristi Yamaguchi in Wikipedia --------------------------------------- Actor John Travolta “Autism and seizures are the least known areas of illnesses.” I will be the first to confess I knew little about Autism until I began talking to a friend at work about his son. The tenderness in his eyes when he talked definitely showed the love he had, and the desire to help and protect his child. There was also a sense of helplessness at facing Autism, and not being able to just make it go away. Parents want to protect and save their offspring, and would give their lives to do so. Physical threats you can see coming are one thing, disorders from within create an anguish that is impossible to describe. From the National Institutes of Health: Autism spectrum disorder (ASD) is a range of complex neurodevelopment disorders, characterized by social impairments, communication difficulties, and restricted, repetitive, and stereotyped patterns of behavior. The hallmark feature of ASD is impaired social interaction. As early as infancy, a baby with ASD may be unresponsive to people or focus intently on one item to the exclusion of others for long periods of time. A child with ASD may appear to develop normally and then withdraw and become indifferent to social engagement. Children with an ASD may fail to respond to their names and often avoid eye contact with other people. They have difficulty interpreting what others are thinking or feeling because they can’t understand social cues, such as tone of voice or facial expressions, and don’t watch other people’s faces for clues about appropriate behavior. They may lack empathy. Many children with an ASD engage in repetitive movements such as rocking and twirling, or in self-abusive behavior such as biting or head-banging. They also tend to start speaking later than other children and may refer to themselves by name instead of “I” or “me.” Children with an ASD don’t know how to play interactively with other children. Some speak in a sing-song voice about a narrow range of favorite topics, with little regard for the interests of the person to whom they are speaking. About 20 to 30 percent of children with an ASD develop epilepsy by the time they reach adulthood. There is no cure for ASDs. Therapies and behavioral interventions are designed to remedy specific symptoms and can bring about substantial improvement. The ideal treatment plan coordinates therapies and interventions that meet the specific needs of individual children. Most health care professionals agree that the earlier the intervention, the better. From the Autism Speaks Website: Autism statistics from the U.S. Centers for Disease Control and Prevention (CDC) identify around 1 in 68 American children as on the autism spectrum–a ten-fold increase in prevalence in 40 years. Careful research shows that this increase is only partly explained by improved diagnosis and awareness. Studies also show that autism is four to five times more common among boys than girls. An estimated 1 out of 42 boys and 1 in 189 girls are diagnosed with autism in the United States. With statistics like these, we all stand an incredible chance of being touched by Autism and its related disorders. Just like me, many will not give it any thought. But then the statistics catch up, and someone you know, even a family member is stricken. Don’t wait until it touches you. Help now. There is a great site called Paracord By Design that sells paracord bracelets, key chains, and lanyards at great prices. This is really nice, but the really cool thing is the Autism Keychain they offer that gives all the proceeds to Autism Research. The notes for this show will include a link to Paracord By Design, and also some great autism resources. http://www.paracordbydesign.com/ National Institutes of Health -Autism Autism Speaks Autism Society -------------------------------------------- SUBSCRIBE! iTunes Stitcher Tunein CHECK US OUT ON Facebook Twitter Tumbler
Dr Mirko Uljarevic (Autism CRC postdoctoral fellow, La Trobe University) talks about the prevalence of stress and anxiety amongst young people with autism spectrum disorders (ASDs), how parents of children with ASDs cope with stress and anxiety, and what support should be in place. Copyright 2015 La Trobe University, all rights reserved. Contact for permissions.
Today we're joined by the group that runs the ASDS charity. Headed by Robin Flutterby, an ambitious and engaging Asperger survivor, and joined by her awesome colleagues, Laura, Amber and Jujo.
Today we're joined by the group that runs the ASDS charity. Headed by Robin Flutterby, an ambitious and engaging Asperger survivor, and joined by her awesome colleagues, Laura, Amber and Jujo.
Health News Segment with: "Dr. Wald, director of Longevity at Integrated MedicineToday topic: Part 6 Autism Epidemic/ASD 6 Part Series The Autism/ASD Epidemic is a profound, eye-opening series of short, informative and practical talks presented by the Dr. Michael Wald - nicknamed the Blood Detective. Dr. Wald explores the criteria for autism and autism spectrum disorders (ASDs), talks about potential causes from all angles and critically evaluates both medical and nutritional and natural treatments. Guest Speaker: Jerry Hocek, PublisherToday topic: Natural Awakenings Magazine Each month Natural Awakenings Magazines across the country take a practical look at the latest natural approaches to nutrition, fitness, creative expression, personal growth and sustainable living. We interview national experts we think you’d like to meet. We offer inspiring how-to articles. Each month brings fresh perspective around a timely theme sure to pique your interest.At the front of each community issue, we present global news and views as a complement to news and events of local interest. We highlight healing arts practitioners in the local area. And we connect you with a wealth of national and local resources mapping out alternate routes to a healthier, happier, longer life. A life that feels good all the way around.
Health News Segment with: "Dr. Wald, director of Longevity at Integrated MedicineToday topic: Part 5 Autism Epidemic/ASD 6 Part Series The Autism/ASD Epidemic is a profound, eye-opening series of short, informative and practical talks presented by the Dr. Michael Wald - nicknamed the Blood Detective. Dr. Wald explores the criteria for autism and autism spectrum disorders (ASDs), talks about potential causes from all angles and critically evaluates both medical and nutritional and natural treatments. Guest Speaker: Sylvia Genders, Product Specialist. Today topic: Organic Natural Oils & Cosmetics New Directions Aromatics a Worldwide distribution of the finest Essential Oils from a leading wholesale supplier of 100% Pure, Therapeutic Grade Essential Oils around the world. Starting with just a handful of distilleries, we now source directly from ethical producers in all six continents. Our volume purchases through our Central Purchasing System enable us to offer the largest selection of pure essential oils at affordable prices. Certificate of Analysis, Specifications and MSDS are available on request. All of our essential oils are ethically produced and are free from pesticides or chemical fertilizers.
Health News Segment with: "Dr. Wald, director of Longevity at Integrated MedicineToday topic: Part 4 Autism Epidemic/ASD 6 Part Series The Autism/ASD Epidemic is a profound, eye-opening series of short, informative and practical talks presented by the Dr. Michael Wald - nicknamed the Blood Detective. Dr. Wald explores the criteria for autism and autism spectrum disorders (ASDs), talks about potential causes from all angles and critically evaluates both medical and nutritional and natural treatments. Guest Speaker: Jerry Hocek, Publisher Today topic: Natural Awakenings Magazine Each month Natural Awakenings Magazines across the country take a practical look at the latest natural approaches to nutrition, fitness, creative expression, personal growth and sustainable living. We interview national experts we think you’d like to meet. We offer inspiring how-to articles. Each month brings fresh perspective around a timely theme sure to pique your interest.At the front of each community issue, we present global news and views as a complement to news and events of local interest. We highlight healing arts practitioners in the local area. And we connect you with a wealth of national and local resources mapping out alternate routes to a healthier, happier, longer life. A life that feels good all the way around.
Health News Segment with: "Dr. Wald, director of Longevity at Integrated MedicineToday topic: Part 3 Autism Epidemic/ASD 6 Part SeriesThe Autism/ASD Epidemic is a profound, eye-opening series of short, informative and practical talks presented by the Dr. Michael Wald - nicknamed the Blood Detective. Dr. Wald explores the criteria for autism and autism spectrum disorders (ASDs), talks about potential causes from all angles and critically evaluates both medical and nutritional and natural treatments.Guest Speaker: Phillip Wilson Today topic: Holistic & Natural Product StoreSince 1980 Momentum98 been selling holistic health products to the public. At Momentum98.com and in our Momentum Health Store, you will find a full array of professional massage tools, homeopathic remedies, alternative health information, household items and personal care wellness products, books, videos, charts, yoga and fitness equipment, and of course, the very popular and affordable Relax Far Infrared Ray Portable Sauna.
Health News Segment with: "Dr. Wald, director of Longevity at Integrated MedicineToday topic: Part 2 Autism Epidemic/ASD 6 Part Series The Autism/ASD Epidemic is a profound, eye-opening series of short, informative and practical talks presented by the Dr. Michael Wald - nicknamed the Blood Detective. Dr. Wald explores the criteria for autism and autism spectrum disorders (ASDs), talks about potential causes from all angles and critically evaluates both medical and nutritional and natural treatments. Guest Speaker: Bruce Stief V.P. Business Development Today topic: Affordable Legal Club Service Family Legal Plan: Unlimited initial phone consultations for each new legal matter. Unlimited initial face-to-face consultations for each new legal matter. Review of important legal documents (6 page maximum). A free simple will with free annual update.Business Legal Plan: Unlimited phone consultations during business hours for all new legal matters. Attorney review of as many as 5 independent documents each month. These include business documents, contracts, signed or unsigned, up to 10 pages each.
Health News Segment with: "Dr. Wald, director of Longevity at Integrated Medicine Today topic: The Autism/ASD Epidemic The Autism/ASD Epidemic is a profound, eye-opening series of short, informative and practical talks presented by the Dr. Michael Wald - nicknamed the Blood Detective. Dr. Wald explores the criteria for autism and autism spectrum disorders (ASDs), talks about potential causes from all angles and critically evaluates both medical and nutritional and natural treatments. Do you have a child or children with ASDs? If not, chances are that you know more than one family dealing, the best that they can, with the inherent difficulties of raising an ASD child. Tell others about Dr. Wald's eye-opening and hopeful exploration of what happens when the Blood Detective takes ASD head-on!Guest Speaker: Daren Autry Manager of Operations Today topic: Free Travel ClubWith 58 years in Business Montrose Travel can Save 8% to 50% Discounts on Vacation Packages, Tours, Hotels, Car Rentals. Competitive pricing and price matching, Personalized Vacation Planners and Travel Consultants, Worldwide 24-Hour Customer Service Program, FREE Flight Insurance – $100,000, Complete Travel Program available both online and offline and much more!
Ultra topic Garage Hour: how to pick, know, and trust the people who keep your car on the road (and how to know you're being screwed). Everything comes across the bench, from how to identify an honest wrench to avoiding being treated like a girl when seeking auto repair, plus a few insightful car-care tricks and the importance of getting a second opinion. Because Garage Hour (duhhh), the show also deep-dives the same itches you like to scratch: IRS illegitimacy, kill-house versus range shooting, how progressivism is next to communism, NASA history, barn finds in old houses, the creeping fungus that is Scientology, detailing Crag's Model T, a few more well-targeted shots at the Bret Stalbaum's nauseating gun-tracking app, and a happy dose of good old fashioned rockabilly. Matt Klier, Lead Instructor @ Active Shooter Defense School, who also happens to be an ASE-certified mechanic, joins Agent Aya, Crag Maxwell (of Maxwell's House of Books in downtown La Mesa, CA) and Hostus Maximus Justin Fort on this excellent episode of Hank Watson's Garage Hour.
Parents Raising a Child with Autism Today show would be my experience raising a child with Autism, please call into the show with your comments and questions.Autism is a neurodevelopmental disorder characterized by impaired social interaction, verbal and non-verbal communication, and by restricted and repetitive behavior. The diagnostic criteria require that symptoms become apparent before a child is three years old. Autism affects information processing in the brain by altering how nerve cells and their synapses connect and organize; how this occurs is not well understood. It is one of three recognized disorders in the autism spectrum (ASDs), the other two being Asperger syndrome, which lacks delays in cognitive development and language, and pervasive developmental disorder, not otherwise specified (commonly abbreviated as PDD-NOS), which is diagnosed when the full set of criteria for autism or Asperger syndrome are not met.
Scratching the itch: the Garage Hour goons join forces with former SEAL Command Master Chief Larry Wilske for two hours of gearheads talking about the big-picture politics that affect your everyday freedoms, and what you (and Larry) need to do to protect them, plus cars, trucks, beers and guns. If you want to get an good impression of the person you're voting for, listen to them on long-form talk radio - Garage Hour talk radio. Starting at gearhead - Evolutions and San Diego's race season, plus Coronado Speedfest, Thunderboats and the upcoming Mirimar Air Show, shooting with Assbleyman Brian Jones, Oktoberfest, and a little bit of former Chargers guys like Dan Fouts and Norv Turner - Justin, Larry and company progress into the work of a congressman and what they're supposed to do as your elected representative, and what the likes of carpetbagging Susan Davis isn't doing for San Diego's 53rd. Joining Larry in-studio are Mr. Dustin (Top Earner), .45 Phil (That Which Goes Bump in the Night), Matt Klier of Active Shooter Defense School, Mike from Barritus Brewery, and Hostus Maximus Justin Fort. We also include a sendoff of cohost Mike's nephew, Lt. Nathan Poloski, the pilot who crashed his USS Carl Vinson-attached FA-18 in the Pacific some weeks ago. R.I.P., airman, you're the best amongst us.
Original Air Date: JULY 22, 2014 | Autism and autism spectrum disorders (ASDs) are on the rise. What we don’t know is if they are actually increasing, or if we are simply better at recognizing the issue. On this episode of CTSI Discovery Radio, we’ll talk about autism in teens and how researchers are trying to help them find their place in society and to thrive.
One of those Garage Hours: everything from tanks to trucks and Speedvision to Jeremy Clarkson punching out Piers Morgan, plus WW2 dogfights, Paths of Hate (just search for the video and you'll understand), the Lake Elsinore Grand Prix, shooting with ASDS in South Bay, local police becoming a staging area for military equipment (dark clouds forming), and the definition of a absentee politician (AKA Tom Harkin). jf
Medizinische Fakultät - Digitale Hochschulschriften der LMU - Teil 16/19
Einleitung: Der Vorhofseptumdefekt (ASD) macht 6 – 10% aller ange-borenen Herzfehler (AHF) aus, im Erwachsenenalter bis zu 40%. 80% aller ASDs sind von Secundum-Typ (II). Sicherheit und Wirksamkeit des Amplatzer-Devices ASO® wurden bereits bewiesen; nichtsdestotrotz traten zum Teil schwere Komplikationen auf, und der Preis ist für Entwicklungsländer zu hoch. Ein neues Device, der Nit-Occlud ASD-R®, gefertigt aus einem Nitinoldraht ohne Lötstellen, mit Polyesthermembranen und Reverse-Konfiguration, entwickelt und hergestellt in Bolivien, soll auch diese Nachteile noch überwinden. Zielsetzung: Vorstellung der kurz- und mittelfristigen Ergebnisse des perkutanen Verschlusses des ASD II mit dem ASD-R® in Bolivien. Methodik: Retrospektive Studie an 55 Patienten, interveniert im größten kardiologischen Zentrum in Bolivien, mit Analyse der Variablen bzgl. Sicherheit und Wirksamkeit des Devices. Ergebnisse: Alter 20,9 ± 16,6 Jahre (3 bis 67); w:m = 40:15. Defektmaß 17 ± 5,7 mm (5,4 bis 28), Device-Stent 18,5 ± 5,5 mm (6 bis 30). Geringere unerwünschte Ereignisse im Zusammenhang mit dem Device traten bei 5 Patienten auf (4 Arrhythmien), nur ein schweres: Embolisierung des trotz Protrusion freigesetzten Devices nach 12h mit chirurgischer Bergung und ASD-Verschluss. Nur in 2 Patienten traten Probleme bei der Liberation auf. Die Verschlussrate am Folgetag war 85,2%, nach 6 Monaten 100%. Schlussfolgerungen: 1. Für die Patienten dieser Studie ist der perkutane ASD-Verschluss mit Nit-Occlud ASD-R® eine wirksame und sichere Methode. 2. Es ereigneten sich weder Erosion noch Perforierung, das Device zeigte sich als atraumatisch. 3. Extrem große Defekte oder ungeeignete Defektränder können andere Methoden (Chirurgie) erfordern.
Jerry Mitchell is on exercises off the coast of Pakistan when his submarine is ordered to a rendezvous off the Iranian coast. Once there, disembarked SEALs, experts in seaborne commando operations, are to extract two Iranian nationals who have sensitive information on Iran's nuclear weapons program.But while en route, the ASDS minisub suffers a battery fire, killing one crew member and forcing the rest of the occupants, four SEALs and LCDR Mitchell, to scuttle their disabled craft and swim for shore. There they find the two Iranians waiting for them, but their attempts at returning to Michigan are thwarted by heavy Iranian patrol boat activity. When agents of Iran's secret police, VEVAK, appear, escape seems all but impossible.
The central theme of this presentation is diagnosis and assessment of autism spectrum disorders. Diagnosis is a clinical endeavor, made by experienced clinicians with knowledge of the features of ASDs. The latter are defined in behavioral terms and fall into three major categories: social, communication, and restricted and repetitive behaviors. Whereas diagnosis is a means of classification, and captures a child’s presentation in a more global way, an important goal of assessment is to document the child’s functioning in a more refined, detailed, and descriptive way for that individual. Assessment is aimed at not only identifying areas of vulnerability but also those areas that are strengths in the child’s profile. Both are relevant to treatment planning.
The following is a guest blog post by Paul Shattuck, PhD, for autismspeaks.org: Do the challenges of having an autism spectrum disorder (ASD) and the needs for special supports magically disappear in adolescence? No! But many families are pushed off a cliff when it comes to accessing needed services for their young adults with an ASD. My team and I used data from a large national survey to look at the use of diagnostic medical services, mental health services, case management, and speech therapy during the first few years after leaving high school. In a report published this month in the Archives of Pediatrics and Adolescent Medicine, we found that overall rates of service use were 23.5 percent for medical services, 35 percent for mental health services, 41.9 percent for case management, and 9.1 percent for speech therapy. This compares with higher rates of service use while in high school: 46.2 percent received mental health services, 46.9 percent had medical services, 74.6 percent were getting speech therapy, and 63.6 percent had a case manager. We also found that 39.1 percent were completely without all four of these essential supportive services. African-American youths and those from poorer households were at much higher risk for this total lack of services. I was especially troubled by the low rate of accessing speech therapy. Youths with an ASD are especially vulnerable during this period because of their core challenges with communication and social interaction. Succeeding at a job, at school, or in the community depends on being able to communicate with other people. Speech therapy can help with these issues. But many insurance plans and state programs for vocational support or serving adults with developmental disabilities do not reimburse for speech therapy. Building in speech therapy as an eligible expense in adult-serving programs should be an immediate priority for policy improvement. Why did I ask these questions? Many people who have, or work with, young people who have special needs already know that services drop off after high school. But there are many people and policy makers who have no clue about how dysfunctional these policies are. This study adds hard facts that can be used to educate and raise awareness about how the current system (mal)functions. The majority of a typical lifespan is spent in adulthood. Yet the majority of what we know about ASDs is based on a lot of research focusing on very young children. I pursued these questions as part of a broader research mission aimed at understanding how to improve life for people with an ASD and their families across the lifespan. Autism Speaks, the Organization for Autism Research, and the National Institute of Mental Health have generously supported this ambitious agenda. I look forward to giving you more updates in the years ahead as we begin to build a stronger evidence base for helping adults with an ASD and their families have brighter futures.
Enhanced Audio Podcast - Part 1Aired date: 8/19/2010 8:00:00 AM Eastern Time
Enhanced Audio Podcast - Part 2Aired date: 8/19/2010 8:00:00 AM Eastern Time
Enhanced Video Podcast - Part 2Aired date: 8/19/2010 8:00:00 AM Eastern Time
Enhanced Video Podcast - Part 1Aired date: 8/19/2010 8:00:00 AM Eastern Time
Symptoms, co-morbidities and monitoring guidelines to inform decisions regarding benefits/risks associated with use of pharmacologic agents to treat behavioral symptoms of autism spectrum disorders.
From the 2005 Summer Institute on Neurodevelopmental Disorders. Recorded Fri, 05 Aug 2005 13:45:00 PST.
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.04.17.047597v1?rss=1 Authors: Chatterjee, M., Singh, P., Xu, J., Lombroso, P., Kurup, P. Abstract: Autism spectrum disorders (ASDs) are highly prevalent childhood illnesses characterized by impairments in communication, social behavior, and repetitive behaviors. Studies have found aberrant synaptic plasticity and neuronal connectivity during the early stages of brain development and have suggested that these contribute to an increased risk for ASD. STEP is a protein tyrosine phosphatase that regulates synaptic plasticity and is implicated in several cognitive disorders. Here we test the hypothesis that STEP may contribute to some of the aberrant behaviors present in the VPA-induced mouse model of ASD. In utero VPA exposure of pregnant dams results in autistic-like behavior in the pups, which is associated with a significant increase in the STEP expression in the prefrontal cortex. The elevated STEP protein levels are correlated with increased dephosphorylation of STEP substrates GluN2B, Pyk2 and ERK, suggesting upregulated STEP activity. Moreover, pharmacological inhibition of STEP rescues the sociability, repetitive and abnormal anxiety phenotypes commonly associated with ASD. These data suggest that STEP may play a role in the VPA model of ASD and that STEP inhibition may have a potential therapeutic benefit in this model. Copy rights belong to original authors. Visit the link for more info
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.04.21.053652v1?rss=1 Authors: Guthman, E. M., Svalina, M. N., Cea-Del Rio, C. A., Kushner, J. K., Baca, S. M., Restrepo, D., Huntsman, M. M. Abstract: Fragile X Syndrome (FXS) is a neurodevelopmental disorder characterized by intellectual disability, autism spectrum disorders (ASDs), and anxiety disorders. The disruption in the function of the FMR1 gene results in a range of alterations in cellular and synaptic function. Previous studies have identified dynamic alterations in inhibitory neurotransmission in early postnatal development in the amygdala of the mouse model of FXS. Yet little is known how these changes alter microcircuit development and plasticity in the lateral amygdala (LA). Using whole-cell patch clamp electrophysiology, we demonstrate that principal neurons (PNs) in the LA exhibit hyperexcitability with a concomitant increase in the synaptic strength of excitatory synapses in the BLA. Further, reduced feed-forward inhibition appears to enhance synaptic plasticity in the FXS amygdala. These results demonstrate that plasticity is enhanced in the amygdala of the juvenile Fmr1 KO mouse and that E/I imbalance may underpin anxiety disorders commonly seen in FXS and ASDs. Copy rights belong to original authors. Visit the link for more info
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