Science of genes, heredity, and variation in living organisms
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It's common knowledge that many diseases and conditions have some kind of genetic link. But that wasn't always the case. In 1990, long before the Human Genome Project tied so many health issues to differences in genetics, researchers identified a gene called BRCA1. It was the first gene linked to a hereditary form of any common cancer. People with certain variants of BRCA1 stood a higher risk of developing breast and ovarian cancer than those without those mutations. Geneticist Mary-Claire King and her lab were the first to identify that gene. She joins Host Flora Lichtman to talk about her background, her research, and her approach to science.Guest: Dr. Mary-Claire King is an American Cancer Society Professor in the departments of Genome Sciences and Medicine at the University of Washington in Seattle.Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.
On Healthy Mind, Healthy Life, host Avik Chakraborty sits down with Julie Alsaker, founder of Lux Bioanalytics and holistic genetic specialist, to unpack how nutrigenomics, methylation pathways, and nervous system regulation shape clarity, energy, and resilience. We move beyond generic wellness advice to explore DNA-informed strategies for burnout, brain fog, and “doing everything right” yet still feeling off. If you've wondered why breathwork, journaling, or clean eating sometimes stall, this episode shows how aligning biology with belief and behavior can create practical, measurable change. About the guest : Julie Alsaker is a holistic genetic specialist with 25+ years in alternative health. Through Lux Bioanalytics, she integrates DNA insights, functional blood analysis, and nutrition to help clients—from bedridden patients to high performers—identify root causes and build sustainable, personalized protocols. Key takeaways: Genetics is strategy, not destiny: DNA reveals tendencies; choices and environments shape outcomes. Nutrigenomics > one-size-fits-all: Diet, stress tools, and routines work best when calibrated to your genetic blueprint. Methylation matters: Variants across 13+ genes (e.g., MTHFR, MTR/MTRR, CBS, COMT) can limit energy access; nutrient form/amount can be the unlock. Biology sets the ceiling: Ignoring physiology (gut, immune, detox pathways) caps results from mindset and mindfulness work. Parasympathetic is where healing happens: Your body repairs when it feels safe; resilience includes nervous system retraining. Symptoms are data, not destiny: Don't normalize persistent brain fog, poor sleep, or “just getting older.” Track and investigate. Gut–brain loop: >70% of serotonin is produced in the gut; microbiome balance influences mood and motivation. Test, then tailor: DNA plus detailed bloodwork narrows root causes and informs targeted, safe interventions. Language shapes physiology: Identity and words matter—reframing fear can reduce stress chemistry and support healing. Start simple: Practice “grounded awareness”—honest symptom logging—before adding protocols or supplements. Connect with the guest : Follow Julie on Facebook: https://www.facebook.com/julie.alsaker Website: https://www.luxbioanalytics.com/ Notes: The episode discusses genetics, nutrition, supplements, and mindset in general, educational terms without making dangerous claims or instructing self-harm. Listeners should consult qualified professionals for personal medical decisions. Want to be a guest on Healthy Mind, Healthy Life? DM on PM - Send me a message on PodMatch DM Me Here: https://www.podmatch.com/hostdetailpreview/avik Disclaimer: This video is for educational and informational purposes only. The views expressed are the personal opinions of the guest and do not reflect the views of the host or Healthy Mind By Avik™️. We do not intend to harm, defame, or discredit any person, organization, brand, product, country, or profession mentioned. All third-party media used remain the property of their respective owners and are used under fair use for informational purposes. By watching, you acknowledge and accept this disclaimer. Healthy Mind By Avik™️ is a global platform redefining mental health as a necessity, not a luxury. Born during the pandemic, it's become a sanctuary for healing, growth, and mindful living. Hosted by Avik Chakraborty—storyteller, survivor, wellness advocate—this channel shares powerful podcasts and soul-nurturing conversations on: • Mental Health & Emotional Well-being• Mindfulness & Spiritual Growth• Holistic Healing & Conscious Living• Trauma Recovery & Self-Empowerment With over 4,400+ episodes and 168.4K+ global listeners, join us as we unite voices, break stigma, and build a world where every story matters.
Unlock strategies to prevent dementia. Discover how genetics impacts brain health. Learn about skincare's surprising role. Explore general health practices for cognitive function. We delve into biohacking your genes. Understand how to age well proactively. This episode reveals key steps for a sharp mind. We discuss lifestyle changes for dementia prevention. Experts share insights on brain health. Learn to optimize your well-being. Discover dietary choices supporting cognition. We explore the power of exercise. Understand stress management's importance. Biohacking techniques can boost brain function. Learn about genetic predispositions. We discuss early detection methods. Proactive steps make a difference. Skincare routines can reflect overall health. We explore the gut-brain connection. Understand sleep's vital role in prevention. Our episode empowers you with knowledge. Take control of your cognitive future. Preventative measures are within reach. We break down complex science simply. Learn practical tips you can implement. Discover the latest research on aging well. Understand the link between inflammation and dementia. We explore innovative approaches to brain health. This episode is your guide to dementia prevention. Start your journey to a healthier brain today. Our Guest: Dr. Sharad Paul Sharad P. Paul, doctor and professor, is the author of several notable nonfiction books for popular audiences in the field of skin, medicine, and genomics such as Skin, a Biography (4th Estate, 2012) and The Genetics of Health (Beyond Words/Atria Books, 2017). He also writes poetry and literary fiction. TIME magazine called him "open heart surgeon," and the NZ Medical Association noted that he has been described as "one of the most inspiring, intelligent, and compassionate men you are likely to meet." In 2015, at APAC, Asia-Pacific's largest health conference, he received the Ko Awatea International Excellence Award for "leading health improvement on a global scale" and for fostering patient-centered medicine across several countries. Learn more at https://skininyourgameblog.drsharadpaul.com/. +++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++ Related episodes: The Brain's Fountain of Youth: Innovative Paths to Dementia Prevention Dementia Brain Protection: Health for Life Preventing Dementia with Dr. Elena ++++++++++++++++++++++++++++++++++++++++. Sign Up for more Advice & Wisdom - email newsletter. Please help us keep our show going by supporting our sponsors. Thank you. ++++++++++++++++++++++++++++++++++++++++ Make Your Brain Span Match Your LifeSpan Relevate from NeuroReserve With Relevate nutritional supplement, you get science-backed nutrition to help protect your brain power today and for years to come. You deserve a brain span that lasts as long as your lifespan. ++++++++++++++++++++++++++++++++++++++++ Feeling overwhelmed? HelpTexts can be your pocket therapist. Going through a tough time? HelpTexts offers confidential support delivered straight to your phone via text message. Whether you're dealing with grief, caregiving stress, or just need a mental health boost, their expert-guided texts provide personalized tips and advice. Sign up for a year of support and get: Daily or twice-weekly texts tailored to your situation Actionable strategies to cope and move forward Support for those who care about you (optional) HelpTexts makes getting help easy and convenient. ++++++++++++++++++++++++++++++++++++++++ List of the Top 20 Alzheimer's Podcasts via FeedSpot! See where we rank. Join Fading Memories On Social Media! If you've enjoyed this episode, please share this podcast with other caregivers! You'll find us on social media at the following links. Instagram LinkedIn Facebook Contact Jen at hello@fadingmemoriespodcast.com Or learn more at Our Website
Who will pass on the legacies, cultivation methods, and unique eye for genetics possessed by the Emerald Triangle legends we all grew up admiring? Today's guest is the answer to that question, along with how classic cuts are being properly preserved, showcased, and bred in new ways to excite modern smokers. Blackleaf is joined in the FSOTD studio by the protege of giants, Leo Stone of Aficionado Seeds to divulge spicy unheard stories about his experience going AWOL from Army Intelligence to pursue the plant, being mentored by OG Mike, how he got involved with Mike and Eddy Lepp's dispo in San Diego, how Leo got the real Lemon Diesel and Purple Urkle, when Cherry Pie Kush cuts were selling for $500k a pop, Kevin Jodrey's impact after setting up HPRC in Arcata, when Leo got his hands on his first 160 acres in Mendo, and so much more.If you've ever wondered what it's like to grow up in a military family, and still have an unquenchable thirst to be involved with the plant, this episode is for you. Leo will detail growing up on base in Japan and how hard it was to get a bag of weed, as well as when he made his decision to go into Army Intelligence, and the moment he got busted for having weed at his residence on base, going AWOL, and eventually getting put on by OG Mike in SD, solidifying his lifer-status in the budding industry.For any cigar smokers out there, Leo will go into deep detail on his former affinity for premium stogies that used to charm him into many important rooms and get him seats at life-changing tables during his military years. This same deep understanding and appreciation of cigars was one of the driving factors in creating Aficionado Seeds, tailor-made for connoisseur
In this episode we talk about the journey and all the BTS adventures of our genetics collab with Swank.Support the show
Are you ready to unravel the mysteries of hormones and their profound effects on your health? How do hormones like estrogen, progesterone, and testosterone impact not just your reproductive system but your overall well-being? Dr. Liz Bartman, a leading naturopathic doctor, guides us through these intricate pathways. What happens to your metabolism when hormones are out of balance? Can environmental toxins really affect your hormonal health? Discover the hidden role of adipose tissue as an endocrine organ and the potential solutions for managing hormonal imbalances. Could estrogen replacement therapy be the key to combating weight gain and metabolic disturbances? How do hormones influence your brain's metabolism and mood? Are you curious about the impact of progesterone sensitivity and the role of neurotransmitters? Dr. Liz dives into these questions, shedding light on how hormones can shape both mental and physical health. In this episode, we uncover: How hormonal imbalances can affect immune response, cognitive function, and blood sugar levels. Why recognizing adipose tissue as an endocrine organ changes our understanding of metabolism. How micro and nanoplastics interfere with hormonal function and weight management. Why progesterone sensitivity can lead to mood fluctuations and neurotransmitter imbalances. How estrogen and histamine interact, affecting mood, energy levels, and PMS. Dive into the fascinating world of hormones with us! This episode is packed with insights that could transform your understanding of health and well-being. Tune in now to explore these crucial topics with Dr. Liz Bartman! Sponsors Order your LMNT electrolytes today and get a FREE 8 pack of samples! Plus try it risk free, they have a no-questions-asked refund policy – you don't even have to send it back! Get 15% off Magnesium Breakthrough By BiOptimzers products at https://bioptimizers.com/hormone with coupon code HORMONE. Are you in peri or post menopause and looking to optimize your hormones and health? At Hormone Solutions, we offer telemedicine services and can prescribe in every U.S. state, as well as in British Columbia, Alberta, and Ontario in Canada. Visit karenmartel.com to explore our comprehensive programs: Bioidentical Hormone Replacement Therapy Individualized Weight Loss Programs Peptide Therapy for weight loss Interested in our NEW Peptide Weight Loss Program? Join today and get all the details here. Join our Women's Peri and Post Menopause Group Coaching Program, OnTrack, TODAY! To our nursing audience members, our podcasts qualify for nursing CE @ RNegade.pro. Provide # CEP17654. Your host: Karen Martel Certified Hormone Specialist, Transformational Nutrition Coach, & Weight Loss Expert Karen's Facebook Karen's Instagram
In this episode, Dr. Melissa A. Ilardo discusses her research on breath-hold diving populations and the genetic adaptations that allow them to thrive in extreme conditions. She emphasizes the importance of language in conducting research, the role of community engagement, and the potential therapeutic applications of her findings. The conversation also touches on the significance […]
What do our genes really reveal about who we are? In this episode, Dr. Pierre Zalloua, geneticist and author of Ancestors, takes us deep into the DNA of the Levant. We explore how personal experience, history, and science intersect to shape identity. From Phoenician expansion to the Crusades, from consumer genetic testing to cultural memory, Dr. Zalloua shows how ancestry is far more complex and more unifying than we might think. We discuss surprising genetic signatures in the Levant, the dangers of oversimplifying identity, and the balance between biology and lived experience. Whether you're curious about your own heritage or the shared human story, this episode offers a profound look at how genetics can illuminate and complicate our understanding of ourselves. #Genetics #Identity #Lebanon #Heritage #Levant #HumanStory #Podcast
In this episode we have another epsidoe in the Grilling the Expert Sereies. This time we are joined by Ben Morrill to talk about the latest in reptile genetics. Follow Justin Julander @Australian Addiction Reptiles-http://www.australianaddiction.comIGFollow Rob @ https://www.instagram.com/highplainsherp/Follow MPR Network @FB: https://www.facebook.com/MoreliaPythonRadioIG: https://www.instagram.com/mpr_network/YouTube: https://www.youtube.com/channel/UCtrEaKcyN8KvC3pqaiYc0RQSwag store: https://teespring.com/stores/mprnetworkPatreon: https://www.patreon.com/moreliapythonradio
Allergist Tina Sindher acknowledges that allergies may be affecting more people worldwide, influenced by a combination of factors such as environmental changes, modern lifestyles, urbanization, and evolving dietary habits. Prevention is playing catch-up, and promising new strategies include earlier food introduction than was popular only a few years ago. On the treatment front, hopes are rising for immunotherapies and a new prescription medicine, omalizumab, that addresses multiple allergens at once. While no single approach helps all, these strategies could allow millions worldwide to better manage their allergies, Sindher tells host Russ Altman on this episode of Stanford Engineering's The Future of Everything podcast. Have a question for Russ? Send it our way in writing or via voice memo, and it might be featured on an upcoming episode. Please introduce yourself, let us know where you're listening from, and share your question. You can send questions to thefutureofeverything@stanford.edu.Episode Reference Links:Stanford Profile: Sayantani (Tina) SindherConnect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / FacebookChapters:(00:00:00) IntroductionRuss Altman introduces guest Tina Sindher, a professor of medicine and allergy at Stanford University.(00:03:16) Inside the Immune ResponseWhy our immune systems trigger allergic reactions.(00:04:57) Genes vs. EnvironmentWhether genetics or environment drive allergy risks.(00:08:05) The Microbiome FactorThe role of the microbiome and early exposures in prevention.(00:09:17) A Global Allergy SurgeHow global allergy trends reveal rising health challenges.(00:11:56) Potent Food TriggersWhy some foods cause stronger and faster reactions.(00:13:49) Emerging RisksWhether Alpha-Gal signals new emerging allergy risks.(00:15:47) Multi-Food AllergiesHow multi-food allergies complicate diagnosis and treatment.(00:19:02) Preventing Allergies EarlyWhy early food introduction may help prevent allergies.(00:20:54) Skin's Role in AllergiesThe importance of infant skin health in allergy development.(00:23:39) Testing LimitationsThe limits of current testing methods to truly diagnose allergies.(00:25:13) Standard Testing ProcedureThe current methodologies deployed when testing for allergies.(00:27:28) New TherapiesHow new therapies like OIT and Xolair are reshaping treatment.(00:31:50) The Future of AllergiesThe potential of combined therapies to aid in allergy treatment.(00:34:33) Managing Seasonal AllergiesHow to manage seasonal allergies effectively at home.(00:37:08) Conclusion Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>>Twitter/X / Instagram / LinkedIn / Facebook
Osteosarcoma Webinar Series: Yanding Zhao, PhD to discuss how Distinct patterns of chromosomal instability fuel osteosarcoma progression and influence patient outcomes.Osteosarcoma (OS) is notable for extreme chromosomal instability (CIN) and molecular heterogeneity, which have hindered therapeutic progress. To address this, the lab performed longitudinal and multi-modal profiling of 91 tumors from 71 pediatric patients, integrating whole-genome and transcriptome sequencing with ATAC-seq and Hi-C in matched cell lines. Their analyses revealed that key driver mutations, including TP53, are fixed early and persist through progression. Over 80% of tumors exhibited complex structural alterations—such as chromothripsis, kataegis, loss of heterozygosity, and ecDNA amplification—with MYC enhancer hijacking linked to chemoresistance. They identified a high-risk evolutionary trajectory marked by homologous recombination deficiency (HRD)-like signatures in the absence of BRCA mutations. These tumors showed focal duplications at fragile sites, early whole-genome doubling, high TP53 mutation burden, and sensitivity to PARP inhibition—highlighting a potential therapeutic vulnerability. Together, these findings define a replication stress–driven model of OS evolution, shaped by early chromosomal remodeling and ecDNA-mediated oncogene activation, with implications for biomarker development and precision treatment strategies.Dr. Yanding Zhao is a postdoctoral researcher at Stanford University in the lab of Dr. Christina Curtis. He earned his PhD in Genetics from Dartmouth College, where he began developing computational tools to understand how genome instability disrupts gene regulation in cancer. At Stanford, his research focuses on pediatric osteosarcoma. By combining genome sequencing, 3D chromatin mapping, and spatial transcriptomics, he studies how tumors evolve, resist treatment, and evade the immune system. Dr. Zhao works closely with clinicians and scientists to help turn these discoveries into potential new therapies. He is honored to be part of the MIB Agents community and looks forward to sharing his work in a way that resonates with patients, families, and advocates.
➢Get coached 1/1 By Me: https://colossusfitness.com/Youtube form playlist: https://youtube.com/playlist?list=PL8OM5ZzYjzbDZnI1iOWB64segChFuQOD7&si=2nvgnkYPbCzEqI0IFree form guide: https://colossusfitness.lpages.co/form-cheat-sheet/Summary of episode:(0:00) - IntroListed points:(00:44) Form over weight, my early squat example, drilling things over and over(05:37) Genetics matter but don't define you(07:16) Enjoy being a beginner more(09:56) Coach(12;31) Bulk the right way / cut the right way(14:09) Celebrate PR's and always set new goals (Learn to love this)(16:01) Don't get enticed by trendsThanks for listening! We genuinely appreciate every single one of you listening.➢Follow us on instagram @colossusfit➢Apply to get your Polished Physique: https://colossusfitness.com/
In this episode of Tiny Show and Tell Us, we talk about cute woolly mammoth mice and debate whether research to bring back extinct species (or their genes) is ethical or a good use of money and time. Then we discuss the best way to remove microplastics from water. We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorite science fact or science news story for a chance to be featured.A transcript and references for this episode can be found at acs.org/tinymatters.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Mitch and Tim return to High on Home Grown for a catch up! It has been a while since we have had them on the show so there is a lot to talk about. Including, some new additions to the Mephisto family, some new strains they will be releasing very soon, and some big awards they have won over the last few months! It is always a massive pleasure to have these guys on the show. We have a great conversation and hope to be doing it again soon, maybe over on their new podcast ;) Don't forget to check out more from Mephisto by listening to our previous interviews with them, and simply just google "Mephisto Genetics" and you will find their website and social media networks there. Mephisto Website: https://mephistogenetics.com/ Thanks as always for listening, I hope you enjoy the interview! Join the discussion about worm farming and living soil over on our forum or Discord—links below! Website: https://highonhomegrown.com Discord: https://discord.gg/sqYGkF4xyQ YouTube: https://www.youtube.com/highonhomegrown Thanks for listening to our cannabis podcast!
In this explainer episode, we've asked Dr Nour Elkhateeb, clinical fellow at Genomics England and clinical geneticist for the NHS, to explain the role of a clinical geneticist. The previous episode mentioned in the conversation is linked below. What is the diagnostic odyssey? You can also find a series of short videos explaining some of the common terms you might encounter about genomics on our YouTube channel. If you've got any questions, or have any other topics you'd like us to explain, let us know on podcast@genomicsengland.co.uk. You can download the transcript or read it below. Florence: What is a clinical geneticist? My name is Florence Cornish and I'm here with Nour Elkhateeb, clinical geneticist for the NHS and fellow at Genomics England, to find out more. So, Nour, before we dive into talking about clinical geneticists, could you explain what we mean by the term genetics? Nour: Hi Florence, so at its heart, genetics is the study of our genes and how they are passed down through families. Think of your genome as a huge, incredibly detailed instruction manual for building and running your body. This manual is written in a specific language, DNA, which is made up of millions of letters arranged in a specific order. And here is the interesting part, we all have tiny differences in our genetic spelling, which is what makes each of us unique. But sometimes a change in the instructions, a spelling mistake in a critical place, can affect health. Genetics is all about learning to read that manual, understand how changes in it can cause disease, how it's passed down through families and finding ways to help. Florence: And so, what kind of thing does a geneticist actually do? Nour: Well, the term geneticist can cover a few different roles, which often work together. Crudely speaking, you can think of two main types, laboratory geneticists and clinical geneticists. Laboratory geneticists are the incredible scientists who work behind the scenes. When we send a blood sample for genomic sequencing, they are the ones who use amazing technology to read the billions of letters in that person's instruction manual. The job is to find the one tiny spelling mistake among those billions of letters that might be causing a health problem. Clinical geneticists like me are medical doctors specialised in the field of genetics, and we work face-to-face with patients and families in a hospital or a clinic setting. You can think of us as the bridge between the incredibly complex science of the genomics lab and the real-life health journey of the person in front of them. We diagnose, manage and provide support for individuals and families who are affected by or at risk of genetic conditions. And we translate that complex genetic information into meaningful information for the patient, the family and the other doctors as well. Florence: So, let's talk a little bit more about clinical geneticists. What stage of someone's genomics journey are they likely to see you? What are some typical reasons they might get referred, for example? Nour: That's a really good question. So, people actually can be seen by clinical geneticists at almost any stage of life, and for many different reasons. Let me give you some examples. We see a lot of babies and children. A family may be referred to us if their baby is born with health problems that do not have a clear cause, or if a child is not developing as expected. And sometimes families may have been searching for answers for years, or what we call a diagnostic odyssey, but no one has been able to find a single unifying diagnosis to explain their challenges. And our job is to see if there is a genetic explanation that can connect all the dots. Florence: You touched there on the diagnostic odyssey, and I know we don't have time to dive into that right now, but if listeners want to learn more about this, then they can check out our previous Genomics 101 podcast: What is the Diagnostic Odyssey? So, Nour, we know that you see children and families in their genomics journeys. Do you see adults as well? Nour: Yes, indeed. We also see many adults who develop certain health conditions, such as cancer or certain types of heart disease, and their clinicians suspect they might be having an underlying inherited genetic cause, or it could be actually someone who is healthy themselves, but have a family history of a particular condition, and want to understand their own risk or the risk for their children and other family members. A classic example is in cancer genetics. A woman with breast cancer at a young age, or who has several family members who have also had it, she would be investigated to see if she carries a gene change that increases the risk of breast cancer and other cancers, and finding that actually would be critical for the treatment choices, and it has huge implications for her relatives. Also, a major part of our work is in the prenatal setting, so we might see a couple during a pregnancy if the antenatal ultrasound scan, for example, shows that the baby has abnormalities. And the obstetrician might refer them to us to investigate if they have an underlying genetic reason for that. And this can help the couple and the medical team prepare for any challenges after birth and also make informed decisions about the pregnancy. And clinical genetics is unique in that we don't see just individual patients, we often work with entire families, and if there is an inherited condition in the family, it's not unusual for several relatives across different generations to be seen by our team. This family-wide approach helps us piece together the inheritance pattern and offer the right tests to the right people, and also ensure that everyone who might benefit from information or screening has the opportunity to access that. Florence: So if someone has a suspected genetic condition, will they always come to you first? Nour: Actually no, the way people come to us is changing. It used to be that you would always see clinical geneticists first, but now with genetic testing becoming more common, other clinicians like a cardiologist, a neurologist, or a paediatrician, might order a genetic test themselves. But these tests can produce a huge amount of data, and the results are not always a simple yes or no. Sometimes the lab finds something called a variant of uncertain significance, which means a gene change that we are not certain whether it is the cause of health problems or not. And in these cases, a specialist will refer the patient to us to help put the uncertain result into the context of the patient's specific health problems, and family history, and to help also work out what it really means for them and their family. Florence: So, you mentioned a couple of other healthcare professionals there, paediatricians and neurologists for example. Are there any other roles that you work closely with as a clinical geneticist? Nour: Well, genetics is never a one-person job, and it's rather like a team sport, so we never work in isolation. We work in what we call a multidisciplinary team, where clinical geneticists, genetic counsellors, genomic practitioners, scientists and other specialists, all bring our knowledge and expertise together. We also work directly with other specialists across the hospital and the NHS. Let's say if it's a genetic heart condition, a cardiologist would be a key part of this multidisciplinary team for the patient. And this 360-degree view ensures that we are giving the best possible holistic care. Florence: And finally, before we wrap up, I'm sure lots of our listeners may have heard or even come across genetic counsellors. Could you explain how this role is different from a clinical geneticist? Nour: So, our role as a clinical geneticist is distinct from that of a genetic counsellor, but we work side by side. Clinical geneticists, as the medical doctors on the team, we're often focused on the diagnosis, and we will perform a physical examination of the patient, looking for subtle clues. We will review their medical history, and piece together the whole medical puzzle. And based on that, we decide which genetic test is the most appropriate, and we'll have the best chance of finding an answer. A genetic counsellor is a healthcare professional with highly specialised training in both genetics and counselling. They are communication experts, they spend time helping families understand results, process the information, and think through what it means for them and their relatives. They are incredibly skilled at explaining complex genetic concepts in a way that is easy to understand, and also at providing support. They help families navigate the emotional impact of what can be life-changing news, and also discuss the implications for the wider family. And genetic counsellors are not only there after the diagnosis is made, they can also play an active role in the diagnostic process. So in many situations, they are the ones taking the detailed family history, recognising patterns that suggest a genetic condition, and arrange the most appropriate genetic tests. They work closely with laboratory scientists and clinical geneticists to interpret the results and guide the next steps for the patient. And a family will often see both of us as our roles complement each other. Florence: So, we'll finish there. Thank you so much, Nour, for sharing what you do as a clinical geneticist. If you'd like to hear more explainer episodes like this, you can find them on our website at www.genomicsengland.co.uk, or wherever you get your podcasts. Thank you for listening.
Adrian Vanvleck is The High Wizard of a magical realm where nerd culture and fitness merge. Adrian's power is creating access for anyone to experience fitness without elitism or gatekeeping. Adrian guests to share his thoughts on:-Are more nerds participating in fitness-What created a portal for nerd culture enthusiasts to be more visible in the mainstream-How can we create room for both our nerdy pursuits and health and fitness-What elitism and gatekeeping looks like in fitness-Why you can't just say you have boundaries, you have to enforce them-Why we can't expect to experience life on easy mode all the time-How to find a system for getting the right calorie intake for your goals without forcing a triggering approach-His experience in a GLP-1 agonist medication scientific trial where he was locked in a metabolic ward for 30 days-And much more00:56 The Rise of Nerd Culture in Fitness06:03 The Impact of Pop Culture on Fitness12:02 Breaking Down Fitness Barriers for Nerds19:02 Setting Boundaries and Overcoming Self-Sabotage26:45 The Stoplight System: Managing Expectations in Fitness31:58 Setting Realistic Fitness Goals32:15 The Importance of Commitment32:26 Managing Expectations in Fitness33:44 Permission and Control in Fitness35:29 Gatekeeping and Elitism in Fitness44:37 The Role of Genetics and Environment in Obesity53:41 Calories and Weight Management59:49 Building a Supportive Fitness CommunityI've been putting a lot of time and effort into making these new episodes valuable for you. You can help me get these great guests and their knowledge in front of more people by:-Subscribing and checking out more episodes-Sharing on your social media (please tag me - I promise I'll respond)-Sharing with the friend you think of who needs this episodeFollow Andrew Coates:Instagram:@andrewcoatesfitnessJoin My Email List:www.andrewcoatesfitness.comGet the RP App at www.rpstrength.com/coates - use the code COATESRPUse Code ANDREWCOATESFITNESS to save 10% off at https://justbitememeals.com/Use MacrosFirst for tracking nutrition https://www.macrosfirst.com/Go to www.knkg.com/Andrew59676 for 15% off your KNKG bag.
A new MP3 sermon from Answers in Genesis Ministries is now available on SermonAudio with the following details: Title: Genetics and the Age of the Earth Subtitle: Answers with Ken Ham Speaker: Ken Ham Broadcaster: Answers in Genesis Ministries Event: Radio Broadcast Date: 9/8/2025 Length: 1 min.
In this week's episode of Bodybuilding Down Under, the team dives into some of the most practical and evidence-based questions in bodybuilding, covering everything from nutrition timing in mini-cuts to the finer details of peak week and show day execution. We start by discussing meal timing in mini-cuts: does it really matter when you're in a steep calorie deficit? Jack, Lawrence, and DY unpack the science around protein distribution, pre-workout fueling, and how timing can influence hunger, performance, and muscle retention during short aggressive dieting phases. Next, we break down the critical elements of peak week and show day preparation. DY shares his insights on the importance of structured routines, hydration, and recovery management, while Jack and Lawrence highlight practical strategies like early starts, using checklists, and having reliable carbohydrate sources on hand. We also tackle the challenge of prepping while travelling, contrasting the realities of trying to maintain contest shape overseas versus allowing more flexibility during the off-season. From there, the conversation shifts to training and genetics in bodybuilding. We explore clavicular width, waist size, and arm/lat/quad insertions, discussing how these genetic traits shape physique categories and what can realistically be influenced by training and posing. The hosts debate whether short biceps with long triceps or vice versa create a more favourable aesthetic, and weigh up the trade-offs between high lat and quad insertions. Finally, the team addresses exercise-induced headaches in training, with practical advice on identifying triggers, modifying exercise selection, and knowing when to seek professional help. This episode is packed with science-driven insights and practical strategies, perfect for anyone looking to refine their contest prep, optimise nutrition timing, or better understand how genetics and training interact in bodybuilding. Instagram Handles: Bodybuilding Down Under: https://www.instagram.com/bodybuildingdownunder/ Jack: https://www.instagram.com/jack.radfordsmith/ Daniel C: https://www.instagram.com/daniel.chapelle/ Lawrence: https://www.instagram.com/general.muscle/ Daniel Y: https://www.instagram.com/dy.fit/
A new MP3 sermon from Answers in Genesis Ministries is now available on SermonAudio with the following details: Title: Genetics and the Age of the Earth Subtitle: Answers with Ken Ham Speaker: Ken Ham Broadcaster: Answers in Genesis Ministries Event: Radio Broadcast Date: 9/8/2025 Length: 1 min.
Guest: Paola Marignani, PhD, EMBA Single-cell RNA sequencing is transforming our understanding of tumor heterogeneity in primary lung cancers by offering insights far beyond traditional bulk sequencing. In this program, Dr. Paola Marignani explores how advanced machine learning enables faster, more precise profiling of genetic diversity, predictive modeling for recurrence and drug resistance, and personalized treatment strategies. Dr. Marignani is a Professor in the Department of Biochemistry and Molecular Biology at Dalhousie University in Halifax, Novia Scotia, and she spoke about this topic at the 2025 World Conference on Lung Cancer.
My guest is Michael Snyder, PhD, professor of genetics at Stanford and an expert in understanding why people respond differently to various foods, supplements, behavioral and prescription interventions. We discuss how to optimize your health and lifespan according to what type of glucose responder you are, which genes you express, your lifestyle and other factors. Dr. Snyder also explains the key ages when you need to be particularly mindful about following certain health practices. We also discuss how people respond in opposite ways to different fiber types. This episode ought to be of interest and use to anyone seeking to understand their unique biological needs and how to go about meeting those needs. Sponsors AGZ by AG1: https://drinkag1.com/huberman Wealthfront*: https://wealthfront.com/huberman David: https://davidprotein.com/huberman Eight Sleep: https://eightsleep.com/huberman Function: https://functionhealth.com/huberman *This experience may not be representative of the experience of other clients of Wealthfront, and there is no guarantee that all clients will have similar experiences. Cash Account is offered by Wealthfront Brokerage LLC, Member FINRA/SIPC. The Annual Percentage Yield (“APY”) on cash deposits as of December 27, 2024, is representative, subject to change, and requires no minimum. Funds in the Cash Account are swept to partner banks where they earn the variable APY. Promo terms and FDIC coverage conditions apply. Same-day withdrawal or instant payment transfers may be limited by destination institutions, daily transaction caps, and by participating entities such as Wells Fargo, the RTP® Network, and FedNow® Service. New Cash Account deposits are subject to a 2-4 day holding period before becoming available for transfer. Timestamps 00:00 Michael Snyder 03:33 Healthy Glucose Range, Continuous Glucose Monitors CGM, Hemoglobin A1c 09:02 Individual Variability & Food Choice, Glucose Spikes & Sleepiness 12:18 Sponsors: AGZ by AG1 & Wealthfront 15:16 Glucose Spikes, Tools: Post-Meal Brisk Walk; Soleus “Push-Ups”; Exercise Snacks 21:06 Glucose Dysregulation, Diabetes & Sub-Phenotypes, Tool: Larger Morning Meal 28:34 Exercise Timing, Muscle Insulin Resistance 30:49 Diabetes Subtyping, Weight, Glucose Control; Incretins 35:41 GLP-1 Agonists, Diabetes, Tool: Muscle Maintenance & Resistance Training 38:40 Metformin, Berberine, Headaches 41:01 GLP-1 Agonists, Cognition, Longevity, Tool: Habits Support Medication; Cycling 47:41 Subcutaneous vs Visceral Fat, Organ Stress 49:10 Sponsors: David & Eight Sleep 51:58 Meal Timing & Sleep, Tools: Post-Dinner Walk, Routines, Bedtime Consistency 57:16 Microbiome, Immune System & Gut; Diet & Individual Variability 1:02:52 Fiber Types, Cholesterol & Glucose, Polyphenols 1:09:50 Food As Medicine; Fiber, Microbiome & Individual Variability; Probiotics 1:18:48 Sponsor: Function 1:20:35 Profiling Healthy Individuals, Genomes, Wearables 1:26:31 Whole-Body MRIs, Nodules, Healthy Baseline, Early Diagnosis 1:34:07 Sensors, CGM, Sleep, Heart Rate Variability HRV, Tools: Mindset Effects, Increase REM 1:39:30 HRV, Sleep, Exercise, Tool: Long Exhales; Next-Day Excitement & Sleep 1:42:48 Organ Aging, “Ageotypes”; Biological Age vs Chronological Age 1:49:41 Longevity, Health Span, Genetics, Blue Zones 1:52:19 Epigenetics, Viral Infection & Disease 1:58:54 ALS, Heritability; Neuroprotection, Nicotine 2:03:47 Air Quality, Allergies, DEET & Pesticides, Inflammation, Mold; Microplastics 2:15:02 Single-Drop Blood Test & Biomarkers, Wearables, Observational Trials 2:20:33 Acupuncture, Blood Pressure 2:26:40 Immersive Events & Mental Health Benefits 2:34:59 Data, Nutrition & Lifestyle; Siloed Health Care vs Personalized Medicine 2:43:06 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Social Media, Neural Network Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices
Evolutionists believe modern humans have been around for hundreds of thousands of years. If that's true, there should be hundreds of genetic mistakes.
What actually causes endometriosis? If you've been struggling with painful periods, fertility challenges, or symptoms that doctors brush off without testing your hormones, you are not alone. Endometriosis is one of the most under-researched and misunderstood conditions women face, even though it can be completely debilitating. In this episode, I break down: Why research is so limited on endometriosis and how that impacts the care women receive. What we do know so far: It's estrogen-driven, and hormone processing plays a big role. Genetics can increase your risk (especially if you're a poor methylator or detoxer). It's often tied to your immune system and can behave like an autoimmune condition. How endometrial tissue behaves once it migrates outside the uterus—it can attach like scar tissue or a web, causing pain, inflammation, and even impacting organs like the bladder or bowel. Why your symptoms are unique: no two women experience endometriosis in the exact same way, which is why dismissive comments like “you can't have it because you got pregnant” are just flat-out wrong. I also share why the DUTCH Test is one of my favorite tools for uncovering the root hormone patterns behind endometriosis. Unlike standard bloodwork, it shows how your body is actually processing estrogen, cortisol, neurotransmitters, and more—giving us a real window into what's going on and where to start. Here's the most important thing: you don't have to guess anymore, and you don't have to do this alone. If you're ready to finally get answers and a plan that's personalized to you, I invite you to apply for my 1:1 VIP Program. In this high-level coaching program, we combine advanced testing like the DUTCH test with a comprehensive strategy tailored to your body—so you can finally start feeling like yourself again. When your body functions better, you feel better. Apply here: https://drbethwestie.com/jumpstart-program/
Elon Musk has often mentioned the potential of mRNA as the "future of medicine" and how he has often thought about the potential of a genetics company harnessing this technology to cure diseases. So in this episode of Moonshot Monday I have a conversation with Ryan Tanaka of Neurapod about what Elon's genetic startup would actually look like. Why he'd launch one (colonize mars, cure diseases), how it would happen, and what its potential would be. This is super speculative, and I'm curious what your thoughts are... do you think Elon Musk will start a genetics/mRNA company????Huge shoutout to Ryan Tanaka for coming on the show follow him on X here: https://x.com/RyanTanaka3OR here's his podcast Neurapod: / neurapod 0:00 Intro: Dire Wolfs & Wooly Mammoths1:27 Why It's Inevitable for Elon Musk to launch a genetics company3:41 ‘Nuke Mars': Humans may need gene editing to thrive on Mars7:23 IVF & New methods of human reproduction8:38 What will Elon's new genetics startup look like?11:01 Tesla's mRNA microfactories during COVID15:52 Neuralink + changing DNA has insane potential to change our biology19:56 How Elon will launch the xGen companyMy X: / gfilche HyperChange Patreon :) / hyperchange
On today's episode of the Iron Sights Podcast, I'm joined by Ryan and CeCe to answer one of the biggest questions in training: how much volume do you really need to build muscle? We break down the science and the practical side of hypertrophy training, covering everything from junk volume and why it slows down your progress, to how close you should be training to failure, to the right number of sets for growth. If you've ever felt confused about whether you're doing too much or not enough in the gym, this conversation will give you the clarity and action steps you need to dial in your program and keep progressing.-25% OFF! Red Dot Fitness Programs: rdfprograms.comRed Dot Fitness Training Programs:rdfprograms.comOnline Membership (Full Access To All Programs & Virtual Coaching):https://www.reddotfitness.net/online-membershipVirtual Coaching:https://www.reddotfitness.net/virtual-coachingSelf-Guided Programs:https://www.reddotfitness.net/Self-Guided-Programs1-(NEW) Iron Sights Podcast Website:ironsightspodcasts.com-Timestamps:00:00 Intro01:50 Program Teaser02:30 Balancing Volume & Intensity03:28 Training Volume For Hypertrophy07:06 Defining & Avoiding Junk Volume13:10 Genetics & Training Volume22:39 Finding The Right Balance For Gains28:47 Balancing Training With Life29:14 Individualizing Your Program36:22 Managing Plateaus & Adjustments41:11 Introducing The Fit For Action Program52:41 Closing Thoughts & Future Plans-Connect With Us:Website - https://ironsightspodcast.com/Instagram - https://www.instagram.com/ironsightspodcast/Facebook - https://www.facebook.com/
Markus Hunter IFBB Pro: @Markusfit The Bodybuilding-friendly HRT Clinic - Get professional medical guidance on peptides AND optimizing your health as a man or bodybuilder: [ Pharma Test, IGF1, Tesamorelin, Glutathione, BPC, Semaglutide, Var troche, etc]http://www.transcendcompany.com/nylenaygaRP Hypertrophy Training App: rpstrength.com/nylePlease share this episode if you liked it. To support the podcast, the best cost-free way is to subscribe and please rate the podcast 5* wherever you find your podcasts. Thanks for watching.To be part of any Q&A, follow trensparentpodcast or nylenayga on instagram and watch for Q&A prompts on the story https://www.instagram.com/trensparentpodcast/Huge Supplements (Protein, Pre, Defend Cycle Support, Utilize GDA, Vital, Astragalus, Citrus Bergamot): https://www.hugesupplements.com/discount/NYLESupport code 'NYLE' 10% off - proceeds go towards upgrading content productionYoungLA Clothes: https://www.youngla.com/discount/nyleCode ‘NYLE' to support the podcastLet's chat about the Podcast:Instagram: https://www.instagram.com/trensparentpodcast/TikTok: https://www.tiktok.com/@transparentpodcastPersonalized Bodybuilding Program: https://www.nylenaygafitness.comTimestamps:0:00 - Intro5:43 - Social Media Perceptions and TikTok Labels10:00 - Content Creation Struggles and Polarization17:15 - Reasons for Mindset Change20:00 - Constructive Criticism and Impact Stories26:43 - Insane Tren Doses and Variations30:00 - Gear, Genetics, and Growth36:38 - Learning Your Body and Coaching45:56 - Sleep Aids and Health Risks50:00 - Crazy Cycle Stories58:19 - Back Training Revelations59:47 - Men's Physique vs. Open Bodybuilding1:10:00 - Chasing the Pro Card Reality1:20:00 - Pro Card Struggles and Triumphs1:28:20 - Importance of Sex in Relationships01:29:56 - Best Prep Look Without Diuretics1:40:22 - Cycle variations01:49:12 - Biohacking for Optimal Performance01:59:40 - Evolving Training Strategies2:10:00 - Next Pod Plans02:12:38 -Best way to use superdrol02:18:57 - Growth Hormone02:30:46 - Gear Guidance for Newbies02:36:05 - Gut Health2:50:00 - Long Prep Secrets02:57:12 - the final message02:59:26 - Being Self/ Family Centered as Men
Message our hosts, Kieran and Jose.Season 3 of The Animal Heartbeat is all about the Veterinary Cardiology Icons - those who walk among us as legends of the veterinary cardiology world.In this episode, we welcome Prof Kate Meurs, Randall B. Terry Jr Dean of North Carolina State University College of Veterinary Medicine. Prof Meurs has worked across the fields of clinical vet cardiology and genetics, and drove the research that led to the discovery of mutations associated with HCM in cats, DCM and ARVC in dogs, and arrhythmia-induced death in particular canine family lines. Her work has changed how we think about heart disease in companion animals, and may hold the key to future refinements in the care we provide for animals with heart disease.Listen to Prof Meurs' reflections on her groundbreaking work, and her thoughts on how we can best use genetic testing to help maximise animal wellbeing in the clinic.
Dr. George Magrath, CEO of Opus Genetics, discusses the company's experience in obtaining non-dilutive funding for its ultra-rare inherited retinal disease program. He highlights the challenges and advantages of this funding source, as well as the importance of establishing relationships with patient advocacy groups and foundations to mitigate risk and increase their attractiveness to traditional investors. The drive for non-dilutive funding for ultra-rare diseases is expected to become increasingly important in helping to get drugs to clinical trials. George explains, "Opus Genetics is a gene therapy company for eye disorders that occur in children. And these disorders are ultra-rare. It's 200 patients, a thousand patients per indication, and it's really good science. It's from Gene Bennett, who was the inventor of Luxturna, which was the first approved genetic medicine. And it does require some non-conventional thought on the financing, though, because these are so rare. And what we've done at Opus Genetics and have been really fortunate to be a part of is non-diluted funding from external sources. And that comes in the form of partnerships with patient families and organizations, like we just announced last week with RDH 12 Alliance." " It also comes with the Foundation Fighting Blindness, which has given us a number of grants and non-dilutive funding deals. And so those have been really important to Opus and have really helped us progress the programs. The way we think about that is the first principle is the clinical data we typically generate using our equity dollars. The preclinical work we try to do with non-dilutive funding, and that way we're able to focus on spending in rare scenarios." #OpusGenetics #RareDiseases #UltraRareDiseases #EyeDiseases #GeneTherapy #NonDilutiveFunding #Blindness #Ophthalmology opusgtx.com Listen to the podcast here
Dr. George Magrath, CEO of Opus Genetics, discusses the company's experience in obtaining non-dilutive funding for its ultra-rare inherited retinal disease program. He highlights the challenges and advantages of this funding source, as well as the importance of establishing relationships with patient advocacy groups and foundations to mitigate risk and increase their attractiveness to traditional investors. The drive for non-dilutive funding for ultra-rare diseases is expected to become increasingly important in helping to get drugs to clinical trials. George explains, "Opus Genetics is a gene therapy company for eye disorders that occur in children. And these disorders are ultra-rare. It's 200 patients, a thousand patients per indication, and it's really good science. It's from Gene Bennett, who was the inventor of Luxturna, which was the first approved genetic medicine. And it does require some non-conventional thought on the financing, though, because these are so rare. And what we've done at Opus Genetics and have been really fortunate to be a part of is non-diluted funding from external sources. And that comes in the form of partnerships with patient families and organizations, like we just announced last week with RDH 12 Alliance." " It also comes with the Foundation Fighting Blindness, which has given us a number of grants and non-dilutive funding deals. And so those have been really important to Opus and have really helped us progress the programs. The way we think about that is the first principle is the clinical data we typically generate using our equity dollars. The preclinical work we try to do with non-dilutive funding, and that way we're able to focus on spending in rare scenarios." #OpusGenetics #RareDiseases #UltraRareDiseases #EyeDiseases #GeneTherapy #NonDilutiveFunding #Blindness #Ophthalmology opusgtx.com Download the transcript here
Genetics are foundational to much of cancer treatment, and now both the environment surrounding the tumor as well as analysis of cancer cells shed into the blood may also be used to inform treatment as well. That's according to studies … A combination of strategies help determine best cancer treatment strategies, Elizabeth Tracey reports Read More »
Host Matt Burgess interviews Gidon Schwartz from Genetics, a UK charity offering pre-conception carrier screening and partnering with the NHS to increase access to BRCA and carrier testing for people with Jewish ancestry. They discuss why ancestry matters for certain recessive conditions, how testing and outreach have evolved, ethical and identity challenges around asking about ethnicity, and where to find resources and genetic counseling.
This is a fan fav episode. Hello, homies! Lisa Bilyeu here! Have you ever dreamt of hitting a 100 years old and still remembering why you walked into the room? Or better yet, still be cracking jokes and doing pushups like it's nobody's business? Well, you're not alone! We're diving headfirst into brain health, exploring adult ADHD, and tackling the truth about how marijuana use has affected my brain health. Without a healthy brain, achieving our grandest goals, spotting narcissists, and dodging toxic relationships become a whole lot trickier. So, if you're ready to join me on this journey and start facing your own hard truths, hit that play button. “Genetics are the bullet but your lifestyle is the finger on the trigger” -Dr. Daniel Amen If tearing up the dance floor and not misplacing your car keys at a hundred (or now) sounds like your cup of tea, then this episode is for you! Don't forget to drop us a rating or review, and share your wild plans for your Golden Girl years. Original air date: 12-29-2023 Check out Lisa's Adult ADHD Diagnosis and Candid Conversation with Dr. Amen: https://youtu.be/DieG5aetBL0?si=eaDSzAet0mZjbj8R Follow Dr. Daniel Amen: Website: https://danielamenmd.com/ YouTube: https://www.youtube.com/@AmenClinic Instagram: https://www.instagram.com/doc_amen/ Learn more about your ad choices. Visit megaphone.fm/adchoices
Thank you for watching!link to original video from piffcoast farms: https://youtu.be/U7Hn9jkBUjM?si=h_1P56CXQ8ozsUmO~ALL BREEDERS SYNDICATE LINKS: https://linktr.ee/riotseeds~SYNDICATE GEAR (shirts, stickers, beanies etc):https://breeders-syndicate-shop.fourthwall.comSUPPORT the channel or JOIN the Discord community:https://www.buymeacoffee.com/matthewriot
Thank you for watching!~ALL BREEDERS SYNDICATE LINKS: https://linktr.ee/riotseeds~SYNDICATE GEAR (shirts, stickers, beanies etc):https://breeders-syndicate-shop.fourthwall.comSUPPORT the channel or JOIN the Discord community:https://www.buymeacoffee.com/matthewriot
Send us a textSupport the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts
DJ Глюк - Жидкий Драм 2 2025 @ DJ Глюк 1. Mr. Sham G - Soul Magnetique 2. DuoScience - Late Afternoon 3. Emba, Lily Denning - Feel Alive 4. Georgie Riot, Tsuki, Sophie-Grace - Without You 5. Izmael - No Signal 6. Tremor - Tell Me 7. Natus, Alpha Rhythm - Ascension 8. Amorius - Look Into My Eyes 9. AYDN - No Ride Home 10. Children Of Our Stars - Take Us Back (VIP) 11. Edlan, Aev.aya - Change Of Heart 12. Genetics, Amber Jay - Habits (Stay High) 13. Ben Vibrant - Olive Tree 14. Flava D, SOLAH - Can't Get It Back 15. Joshua dnb - Unbroken 16. Oversight - Smoke And Fire
Today, we're looking in to the fascinating world of telomeres—those tiny caps at the ends of our DNA that play a massive role in how we age. In this solo episode, I break down exactly what telomeres are, why they matter for our health and longevity, and how everything from stress, sleep, and diet to genetics can impact their length. You'll also hear about the latest research, eye-opening real-life cases, and some cutting-edge interventions that might just help you preserve—or even lengthen—your telomeres. Listeners of this podcast can get a quick list of my top five peptides here (for FREE): natniddam.com/top5 Episode Timestamps: Telomeres and disease ... 00:07:12 Lifestyle factors harming telomeres ... 00:07:58 Chronic stress and resistance ... 00:08:28 Lifestyle interventions ... 00:10:52 Sleep and foundational habits ... 00:11:52 Genetics and telomerase ... 00:12:39 Early life impacts ... 00:15:01 Supporting telomeres: exercise, diet ... 00:16:46 Diet research, mindfulness ... 00:17:12 Oral health ad ... 00:18:31 Social connection and purpose ... 00:20:39 Clinical research and therapies ... 00:22:03 Gene and plasma therapies ... 00:23:27 Pineal gland bioregulator ... 00:25:44 Bioregulator research ... 00:29:18 Key supplements ... 00:29:50 Genetics and telomere length ... 00:34:49 Our Amazing Sponsors: OraltidePro - A unique mouthwash that: Promotes growth of shrinking gums, Speeds healing of mouth & tongue, Prevents oral infections (such as gingivitis), Helps with enamel remineralization, Reduces bacteria growth and etching and Fills slots in damaged enamel. check out OraltidePro at profound-health.com and use code NAT15 for 15% off your first order. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group
If you've ever thought, “I just can't stop eating sugar,” this episode is for you. I'll share what I discovered while reviewing 20 nutrition genomic reports from breast cancer survivors—and the surprising genetic commonalities that explain both difficulties with blood sugar regulation and stronger tendencies toward impulsive cravings. You'll also learn how cancer cells use insulin receptors to fuel their growth, why sugar is about more than just sweets, and how your brain and body work together in the cycle of cravings. Plus, I'll walk you through The 5 S's framework—a simple set of tools to calm cravings and create a terrain that supports healing. Listen now and discover how to nourish yourself with more confidence and trust. Explore more support: Better Than Before Breast Cancer Life Coaching Membership: https://www.thebreastcancerrecoverycoach.com/lifecoaching Take the free Sugar Challenge here: https://www.thebreastcancerrecoverycoach.com/sugar Let's Connect! If this episode helped you breathe a little easier, please share it with a friend or leave a review. Every share helps spread this message of hope, healing, and whole-person wellness.
Check out our previous podcast with Dr. Niraj Rai - https://youtu.be/aRkKUA9lZ9Q?si=2BTXYby0NmdxMJE9Check out BeerBiceps SkillHouse's YouTube 1O1 Course - https://youtube.beerbicepsskillhouse.in/youtube-101Share your guest suggestions hereMail - connect@beerbiceps.comLink - https://forms.gle/aoMHY9EE3Cg3Tqdx9BeerBiceps SkillHouse को Social Media पर Follow करे :-YouTube : https://www.youtube.com/channel/UC2-Y36TqZ5MH6N1cWpmsBRQ Instagram : https://www.instagram.com/beerbiceps_skillhouseWebsite : https://beerbicepsskillhouse.inFor any other queries EMAIL: support@beerbicepsskillhouse.comIn case of any payment-related issues, kindly write to support@tagmango.comLevel Supermind - Mind Performance App को Download करिए यहाँ से
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In this episode, we discuss the comprehensive guide 'The Expert Guide to Fertility: Boost Your Chances for Pregnancy' by Dr. Artie Kumar and Dr. Sanfilippo. The book provides crucial information on navigating the challenging journey to fertility. Dr. Kumar shares the background and vision behind the book, recounting how it was shaped by her and Dr. Sanfilippo's experiences and conversations with patients. The discussion covers diagnostic tests for fertility, treatment for endometriosis, and the importance of understanding medical, emotional, and financial aspects of fertility. Additionally, Dr. Kumar offers insights into how the book aims to educate and empower readers by giving them the vocabulary to better communicate their experiences and needs. Read the full show notes on my website. Get The Expert Guide to Fertility: https://www.amazon.com/Expert-Guide-Fertility-Chances-Pregnancy/dp/1421447061/ Would you like to learn more about IVF?Click here to join Dr. Aimee for The IVF Class. The next live class call is on Monday, September 15th, 2025 at 4pm PST, where Dr. Aimee will explain IVF and there will be time to ask her your questions live on Zoom. Subscribe to my YouTube channel for more fertility tips! Subscribe to the newsletter to get updates Dr. Aimee Eyvazzadeh is one of America's most well known fertility doctors. Her success rate at baby-making is what gives future parents hope when all hope is lost. She pioneered the TUSHY Method and BALLS Method to decrease your time to pregnancy. Learn more about the TUSHY Method and find a wealth of fertility resources at www.draimee.org.
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In Episode 179, Phil and Paul engage in an eclectic and wide-ranging conversation with Greg Rubendall, who has recently started a new venture in Sacramento, ASC Midtown, and a new podcast, “The Road Warrior.” The episode covers topics from personal updates to more philosophical discussions touching on biomechanics, conservation genetics, classical literature, leadership, and the power of unstructured play. Greg shares his insights on the importance of continual learning, community development, and creating environments where everyone can flourish. This engaging dialogue also explores the impact of technology in sports and the unique developmental methods observed in European soccer academies. You definitely don't want to miss this one. Resources and Links from this Episode · Uncut Video of the Episode · Warrior Way Soccer · Phil's email for DISC Training · Candide, Voltaire · Start with Why, Simon Sinek · “Start with Why” TED Talk
In this week's episode, we'll learn about how TET2 is often mutated in myeloid malignancies and clonal hematopoiesis. In new work, expansion of Tet2-mutant HSPCs was dependent on Ncoa4, the cargo receptor mediating ferritinophagy. We'll iron out the implications. After that: a double-oh-seven license to kill in T-cell leukemia/lymphoma. WU-CART-007 is an off-the-shelf CAR T product with manageable safety and encouraging efficacy. With further work, it could become a new option for patients in urgent need of therapy. Finally: a comprehensive genetic study of classical Hodgkin lymphoma using circulating tumor DNA. This new research provides novel and complex insights on genetic subtypes, prognostic biomarkers, neoantigens in the disease environment, and more.Featured Articles:An in vivo barcoded CRISPR-Cas9 screen identifies Ncoa4-mediated ferritinophagy as a dependence in Tet2-deficient hematopoiesisPhase 1/2 trial of anti-CD7 allogeneic WU-CART-007 for patients with relapsed/refractory T-cell malignanciesA comprehensive genetic study of classic Hodgkin lymphoma using circulating tumor DNA
"We spend about $528 billion a year fixing the mistakes we make with medicines." - Chris GrilliFixing healthcare's $528 billion dollar mistake starts with ending the "trial-and-error" prescribing that plagues our system. My guest this week, pharmacist and genomics expert Chris Grilli of RxMapper, joined the show to explain how personalized, DNA-guided medicine is the key to solving this massive problem.Chris breaks down the RxMapper model, explaining how they analyze 36 million data points from a patient's genome to provide medication recommendations with nearly 90% accuracy. We discuss the crucial difference between genetics and genomics, and how this approach saves thousands of dollars per patient while dramatically improving outcomes.The mission to fix this problem is also a personal one. Chris shared the story of how his grandmother's preventable death from an adverse drug event became the inspiration for building RxMapper to ensure other families don't suffer the same fate.Tune in this week for the playbook on fixing one healthcare's most expensive mistakes.Chapters:(00:00:00) Fixing Healthcare's $528 Billion Dollar Mistake (00:02:12) The $528 Billion Cost of Medication Errors (00:04:43) Genetics vs. Genomics: What's the Difference? (00:10:29) Are Doctors Prescribing "Poison?" (00:14:18) The Personal Story Behind RxMapper (00:27:17) Saving Over $8,600 Per Patient (00:41:24) How Your DNA Impacts Ozempic's EffectivenessKey Links for Social:@SelfFunded on YouTube for video versions of the podcast and much more - https://www.youtube.com/@SelfFundedListen/watch on Spotify - https://open.spotify.com/show/1TjmrMrkIj0qSmlwAIevKA?si=068a389925474f02Listen on Apple Podcasts - https://podcasts.apple.com/us/podcast/self-funded-with-spencer/id1566182286Follow Spencer on LinkedIn - https://www.linkedin.com/in/spencer-smith-self-funded/Follow Spencer on Instagram - https://www.instagram.com/selffundedwithspencer/
Every year tens of thousands of Australians turn to IVF to start or grow a family.But is it an industry that can be fully trusted given recent revelations of embryo and sperm mix-ups and women giving birth to strangers' babies?Today, ABC journalist Grace Tobin on her latest investigation into one couple's fraught experience and why the rules need to change.Featured:Grace Tobin, ABC Investigations reporter
Lending his 25-year-old OLD soul voice, Canadian Liev Dalton, creator and host of his podcast and collective Beyond Terrain, shares his truth awakening story from his time in college. He observed firsthand the flaws of academia and science, from germ theory to PCR tests, and used the lockdown period to study, reflect and think critically. In our episode, he discusses the nature of law, fires, glyphosate spraying, whole terrain, synthetics, toxins and talks of dentistry by highlighting the studies of Canadian dentist, Westin A. Price. PS - he now has a master's in counseling psychology and runs a wilderness therapy practice. Closing with the "Just Be Practice," he encourages us to look outward so we can turn inward.Show Reference:Westin A. Price: https://www.westonaprice.org/#gsc.tab=0Connect with Liev:Website: https://BeyondTerrain.com/beyond-terrain-academy IG: https://www.instagram.com/beyond.terrain/?hl=en*Host Eden Koz is a soul realignment specialist utilizing psychological empathy, intuition, psychic ability, mediumship, meditation, mindset shift, Reiki, dimensional and galactic healing, to name a few. She also performs spiritual Co#id Vac+ Healing as well as remote & face-to-face sessions with individuals and groups. Contact info for Eden Koz / Just Be®, LLC:Website: EdenJustBe.com Socials: Insta, FB, FB (Just Be), TikTok, LinkedInJust Be~Spiritual BOOM Podcast can be found on Video directories: BitChute, Rumble, YouTube, Odysee, Grassroots Warrior Network. Audio directories: Apple Podcasts, Spotify, ...
In this episode of the Ageless Future podcast, host Cade Archibald speaks with Dr. Sam Shea, a functional medicine expert who turned his personal battles with chronic fatigue, insomnia, digestive issues, and anxiety into a 25-year mission to help others reclaim their vitality. Dr. Shea explains his NeuroHarmony model, which combines comprehensive lifestyle assessments with five categories of lab testing—hormones, gut health, mitochondrial function, environmental toxins, and genetics—to identify and address the root causes of burnout and chronic illness. He shares insights on functional genetics, such as tailoring diet to individual carb tolerance, prioritizing health interventions to avoid overwhelm, and understanding evolutionary trade-offs in genetic traits. With a focus on entrepreneurs, Dr. Shea emphasizes that health is a business investment, advocating for data-driven strategies to optimize performance, longevity, and quality of life. Website: www.DrSamShay.comYouTube/Podcast: https://www.youtube.com/tenpointwellness Facebook: https://www.facebook.com/sam.shay.792/Instagram: https://www.instagram.com/drsamshay/LinkedIn: https://www.linkedin.com/in/dr-sam-shay-dc-ifmcp-922133128/
-Medical industry vs. Natural Medicine: treating symptoms vs. bringing hope & healing for chronic illness-Genetics vs. environment-Test, don't guess-Where to start with cleansing & detoxTo find out how we can help you on your health journey, book a free 15-minute Discovery Call with one of our New Client Coordinators! Click the link: https://www.spiritofhealthkc.com/disc...For more health tips and information visit: http://www.spiritofhealthkc.comTo buy natural health supplements visit: http://store.spiritofhealthkc.comTo find out how we can help you on your health journey, book a free 15-minute Discovery Call with one of our New Client Coordinators! Click the link: https://www.spiritofhealthkc.com/discoverycall For more health tips and information visit: https://www.spiritofhealthkc.com/To buy natural health supplements visit: http://store.spiritofhealthkc.com Facebook: https://www.facebook.com/SpiritofHealth/ Instagram: https://www.instagram.com/spiritofhealthkc/ Pinterest: https://www.pinterest.com/spiritofhealthkc/YouTube: https://www.youtube.com/channel/UCwRcNSxR3kMYi9wP8OmxlQQ Spotify: https://open.spotify.com/show/7yfBBUjWKk3yJ3auK71O7H?si=295c77ed21f14568&nd=1&dlsi=af01c00121ed4aed
Alzheimer's is not inevitable—and it may even be optional. In this groundbreaking episode, you'll learn how to prevent, slow, and in some cases reverse cognitive decline using strategies that also enhance brain optimization, metabolism, and longevity. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey is joined by Dr. Dale Bredesen, a world-renowned neurologist and leading Alzheimer's researcher who has published over 240 peer-reviewed papers. Dr. Bredesen has spent decades proving that Alzheimer's is not a one-pathway disease but a network failure driven by inflammation, toxins, and mitochondrial dysfunction. His protocol has helped thousands of patients regain memory, extend healthspan, and reclaim brain performance. Together, they unpack how biohacking tools like fasting, ketosis, supplements, sleep optimization, cold therapy, and functional medicine can rewire neuroplasticity, protect mitochondria, and keep the brain in “connection mode” instead of decline. You'll hear why the pharmaceutical industry resists these solutions, how toxins like Paraquat and mold fuel cognitive decline, and what young people can do right now to bulletproof their brains for life. This episode is essential listening if you care about hacking human performance, upgrading metabolism, or extending longevity. You'll walk away with practical strategies you can use today—whether that means optimizing your mitochondria with nootropics, strengthening resilience with smarter not harder recovery, or fueling your brain with Danger Coffee. You'll Learn: • Why Alzheimer's can begin as early as your 20s and what biomarkers to track • The seven major drivers of Alzheimer's and how to reverse them with biohacking strategies • How APOE4 genetics, toxins, and inflammation accelerate brain aging—and what to do about it • The role of mitochondria, ketosis, and fasting in restoring brain optimization and neuroplasticity • Why prevention is exponentially easier than reversal and the top three actions you should start in your 20s • How to avoid “learned helplessness” in medicine and reclaim control over your brain span and longevity Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: Alzheimer's prevention biohacking, APOE4 genetics risk, mitochondrial dysfunction brain, network insufficiency model, cognitive decline reversal protocol, neuroplasticity longevity strategies, mild cognitive impairment treatment, subjective cognitive impairment biomarkers, ketoflex 12/3 diet, mycotoxins and Alzheimer's, Paraquat Parkinson's risk, mitochondrial transfusion therapy, fasting neuroprotection, ketosis brain optimization, natokinase soft plaque removal, sleep apnea cognitive decline, functional medicine Alzheimer's, hippocampal volume preservation, nootropics cognitive resilience, learned helplessness medicine Thank you to our sponsors! EMR-Tek | Go to https://www.emr-tek.com/DAVE and use code DAVE for 40% off.fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. OneSkin | Get 15% off your first purchase at https://oneskin.co/ASPREY with code ASPREY. Resources: • Dale's Website: https://www.apollohealthco.com/dr-bredesen/ • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:10 — Introduction 2:43 — Personal Story 7:52 — APOE4, Genetics, and Drug Development 11:37 — Pharma, Media, and Pushback 17:13 — Prevention, Stages, and Biomarkers 23:34 — Causes and Mechanisms 30:24 — Parkinson's, Toxins, and Mitochondria 37:17 — Longevity, Biohacking, and Protocols 44:11 — AI, Data, and Future Treatments 54:11 — Case Studies and Success Stories 1:03:00 — Detox, Mold, and Environmental Triggers 1:12:00 — Neuroplasticity and Brain Regeneration 1:20:00 — Hormones, Supplements, and Personalized Hacks 1:29:00 — Cortisol, Addison's, and AI Protocols 1:38:00 — Large-Scale Trials and Global Impact 1:45:00 — Final Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.