Podcasts about Genetics

The Mechanics of Genetic Drift Plants are natural genetic mosaics. As they grow and divide over time, typos naturally accumulate in their DNA code, which are known as somatic mutations. Traditional vegetative cuttings and field-grown plants accumulate these mutations at a very low, linear baseline rate over decades. However, the extreme genomic degradation highlighted in the paper is driven by rapid generational cell cycling in vitro. Forcing an unorganized mass of cells to constantly divide and regenerate bypasses the plant's normal cellular quality control checkpoints. Somatic Embryos vs. Meristem Cultures Somatic embryogenesis involves stripping a plant down to a single cell or callus phase to regenerate an embryo. This is considered high risk for mutations because if the founder cell contains a mutation, that mutation becomes permanently fixed in every single cell of the thousands of plants propagated from it. This differs from meristem tip culture, which is the low risk, predominant form of tissue culture used in cannabis for clearing Hop Latent Viroid. Because meristem tip culture preserves the existing, highly organized architecture of the shoot apical meristem rather than forcing single cells to reprogram, the genetic risk is fundamentally lower. DNA Typos vs. Chromosome Catastrophes The high-stress cell cycling environment caused macroscopic genomic errors, such as whole-chromosome duplications called trisomies. In the walnut clones, these large-scale errors made it incredibly difficult to grow the tissue back out into healthy adult plants. The stress of rapid lab cell cycling also desilenced transposable elements, or jumping genes, allowing pieces of DNA to insert themselves randomly throughout the genome and disrupt normal gene expression. It is worth noting that not all mutations are bad. Small point mutations, or single base changes, happen constantly in nature as life being life. Most occur in non-coding regions and have zero impact, while a rare few can actually create desirable new traits as seen historically in citrus and wine grapes. Genetics vs. Epigenetics The guests distinguish between true genetic mutations, which are permanent changes to the A, C, T, G code, and epigenetic modifications, which act like chemical bookmarks such as methylation that change how a gene is read without altering the underlying sequence. Some instances of a mother plant losing vigor may actually be epigenetic shifts caused by environmental stress or endophyte and pathogen buildup over time, rather than a permanent genetic mutation. Actionable Advice for Cannabis Nurseries Commercial operations scaling up clones to the tens of thousands should utilize genetic sequencing early in the pipeline. Testing the early founder material can easily catch large-scale catastrophic mutations like chromosome duplications or deletions, protecting the nursery from mass-producing defective production plants. Whole-genome sequencing costs have plummeted significantly, and the guests encourage cultivators and nursery operators with unique, degenerating, or shifting clonal lines to collaborate with academic labs to sequence the data and map exactly what is changing. Guest Information and Contact Details J. Grey Monroe is an Associate Professor in the Department of Plant Sciences and the Genome Center at UC Davis. His lab studies how mutations arise across genomes, DNA repair, epigenomics, and genome evolution in plants, with applications in crop improvement and protection. Lab website: https://monroelab.org/ Email: gmonroe@ucdavis.edu Matthew Davis is a fifth year PhD candidate in the Plant Biology Graduate Group co-advised by Grey Monroe and Pat J. Brown. His research focuses on somatic mutation in orchard crops, an understudied genetic process that directly affects one of California's largest agricultural industries. Bluesky: @davismw.bsky.social Email: mtdavis@ucdavis.edu Research Links and Resources Peer-Reviewed Paper: https://www.pnas.org/doi/10.1073/pnas.2530182123 Shorter general audience article: https://www.ucdavis.edu/blog/not-all-clones-are-created-equal Slightly longer general audience article: https://www.plantsciences.ucdavis.edu/news/davis-monroe-somatic-mutations Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

From cosmic rays to solar storms, space travel is a radiation gauntlet—but water may be the simplest, smartest solution. Discover how future starships might turn their life-support systems into life-saving armor.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurWatch my exclusive video Nearby Supernovae: https://nebula.tv/videos/isaacarthur-nearby-supernovae-could-one-destroy-earth-and-could-we-stop-itCheck out Gods & Monsters: https://nebula.tv/curiousarchive/gods-and-monsters?ref=isaacarthur

From cosmic rays to solar storms, space travel is a radiation gauntlet—but water may be the simplest, smartest solution. Discover how future starships might turn their life-support systems into life-saving armor.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurWatch my exclusive video Nearby Supernovae: https://nebula.tv/videos/isaacarthur-nearby-supernovae-could-one-destroy-earth-and-could-we-stop-itCheck out Gods & Monsters: https://nebula.tv/curiousarchive/gods-and-monsters?ref=isaacarthur

This is part two of a ten-part podcast series documenting the European Industrial Hemp Association's 23rd Annual Conference in Poznan, Poland, at the Institute of Fiber Plants and Medicinal Medicine, June 10-12. Witold Czeszak, co-founder and head of the Polish Hemp Program at the Institute of Natural Fibers and Medical Plants, talks about Polish hemp genetics, the importance of IP protection and why he fought hard to bring the European Industrial Hemp Conference to the Institute. "I brought to the table new blood. I brought here representatives of huge companies because in general my idea is to professionalize the sector so to scale it up, keeping of course quality on the highest level," he said. Poland has been at the epicenter of hemp in Europe for decades, and with genetics like Hanola and Białobrzeskie coming out of Czesak's breeding program, Polish varieties have become standard fiber genetics around the world. Learn More Institute of Natural Fibers and Medicinal Plants (IWNIRZ) iwnirz.pl European Industrial Hemp Association (EIHA) eiha.org/ EIHA Conference eiha-conference.org/ Thanks to Our Sponsors HEMI — The Hemp Education and Marketing Initiative thegoodnessofhemp.org Bish Enterprises — FiberCut Hemp Harvesting bishenterprise.com/fibercut 1937 International 1937international.com Condor Seed condorseed.com

Can antimatter be stored safely? Explore magnetic traps, starship fuel, and the terrifying challenge of bottling energy that destroys any container it touches.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurWatch my exclusive video Nearby Supernovae: https://nebula.tv/videos/isaacarthur-nearby-supernovae-could-one-destroy-earth-and-could-we-stop-it

Can antimatter be stored safely? Explore magnetic traps, starship fuel, and the terrifying challenge of bottling energy that destroys any container it touches.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurWatch my exclusive video Nearby Supernovae: https://nebula.tv/videos/isaacarthur-nearby-supernovae-could-one-destroy-earth-and-could-we-stop-it

At Lifespan, our mission is to help you and your loved ones live your longest, healthiest lives while supporting medical research into breakthroughs to improve all lives. We're building the world's largest longevity community: Join us at https://lifespan.com. Follow us on YouTube, Apple, and Spotify for new Lifespan episodes every 2 weeks.                               __________________________________________ In this episode of Lifespan Season 2, Dr. David Sinclair, A.O., Ph.D. – Professor of Genetics at Harvard Medical School and pioneer in longevity research – explores the science of calorie restriction and fasting, two of the most studied interventions for healthy aging. Drawing on decades of research, Dr. Sinclair explains how eating less – and eating less often – affects the biology of aging, why our evolutionary past may predispose many of us to weight gain, and what the latest human and animal studies reveal about lifespan, metabolism, and disease risk. Whether you're interested in longevity, metabolism, or intermittent fasting, this episode provides an evidence-based look at one of the most powerful strategies for supporting health and longevity.                                __________________________________________ Partners of the Lifespan show help us keep this program freely available as an educational resource while also supporting medical research. We only collaborate with partners whose products are grounded in science and that our team has personally used for years. Our selected partners make it convenient for the Lifespan audience to access the tools and technologies featured in this episode - from exogenous fuel for neurons (Ketone-IQ), to wearables that track recovery, strain, and sleep (WHOOP), to smart devices that measure key health metrics such as visceral fat and muscle mass (Withings). If you'd like to learn more or try these tools: ○ Ketone-IQ: Get 30% off your first monthly order at https://ketone.com/lifespan or with code LIFESPAN ○ WHOOP: Get a free WHOOP band and one month of membership at https://join.whoop.com/LIFESPAN or with code LIFESPAN ○ Withings: Get 10% off smart health devices at https://withings.com/lifespan or with code LIFESPAN                                __________________________________________ Legal & Medical Disclaimers The Lifespan show and all related content are provided for informational and educational purposes only and are not intended as medical advice, diagnosis, or treatment. Nothing presented should be interpreted as a recommendation to diagnose, treat, cure, or prevent any disease or medical condition. This content is not a substitute for professional medical advice, diagnosis, or treatment from a qualified healthcare provider. You should always consult with a licensed physician or other qualified healthcare professional before making decisions about your health, including starting, stopping, or modifying any treatment, supplement, diet, or exercise program. The information shared reflects the views and opinions of the host and guests and is based on the scientific literature, their experience and expertise, and general wellness principles. Listening to or engaging with Lifespan content does not establish a doctor–patient or clinical relationship.  Health and longevity outcomes can vary significantly between individuals. Any references to studies, interventions, products, or protocols are not guarantees of specific results, and individual responses may differ. From time to time, Lifespan may discuss or partner with third-party products or services. These references are provided for informational purposes only and should not be considered medical recommendations or endorsements of efficacy for any individual. Lifespan Foundation is an independent 501(c)(3) non-profit organization whose mission is to support medical research.   The views expressed by Dr. David Sinclair, A.O., Ph.D., are his own and do not represent those of Harvard University, Harvard Medical School, or any affiliated institutions.

Jenny Kleeman investigates ‘Biotech Barbie' Cathy Tie, the controversial entrepreneur hoping to revolutionise human reproduction by letting parents edit their embryos. Help support our independent journalism at theguardian.com/infocus

How much do our genes determine about our lives, and could they influence traits like risk-taking, antisocial behaviour or even violence? Ian Sample talks to Kathryn Paige Harden, a behavioural geneticist and professor of psychology at the University of Texas at Austin who studies how genetic factors shape human behaviour. In her book Original Sin she explores how nature and nurture combine to influence our likelihood of committing crimes, and asks whether the ‘cause' of our actions matters for how we think about culpability. Help support our independent journalism at theguardian.com/sciencepod

What if we found a true second Earth nearby? A living world, a barren paradise, or something too familiar to be natural could change science, politics, and humanity's future forever.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurWatch my exclusive video Nearby Supernovae: https://nebula.tv/videos/isaacarthur-nearby-supernovae-could-one-destroy-earth-and-could-we-stop-itCheck out Gods & Monsters: https://nebula.tv/curiousarchive/gods-and-monsters?ref=isaacarthur

What if we found a true second Earth nearby? A living world, a barren paradise, or something too familiar to be natural could change science, politics, and humanity's future forever.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurWatch my exclusive video Nearby Supernovae: https://nebula.tv/videos/isaacarthur-nearby-supernovae-could-one-destroy-earth-and-could-we-stop-itCheck out Gods & Monsters: https://nebula.tv/curiousarchive/gods-and-monsters?ref=isaacarthur

He carried two copies of ApoE4, the highest genetic risk factor for Alzheimer's disease, went through medical school knowing exactly what his LDL of 700 meant, decided the experts were wrong, and then published the case report to prove it. In this episode, Louisa sits down with Dr. Nick Norwitz, PhD researcher and metabolic scientist, for one of the most scientifically dense conversations on brain health, cholesterol biology, and Alzheimer's prevention ever recorded on this show. They cover why the phospholipid form of DHA reaches the brain more effectively than standard fish oil, how ApoE4 carriers burn through omega-3s differently and what to do about it, the lithium orotate data that sold out supplement shelves worldwide, and why GSK-3 beta, the enzyme that phosphorylates tau, may be the most under appreciated target in Alzheimer's research today. Then Dr. Nick Norwitz lays out the case that challenges the "LDL is always the enemy" consensus: why metabolically healthy individuals may not benefit from aggressive lipid-lowering therapy, what his viral coronary CT angiogram showed after seven years of 700+ cholesterol, why the EZPAVE trial headlines don't hold up under scrutiny, and what GLP-1s are doing inside the brain completely independent of weight loss. You'll also hear about the sardine diet experiment, the omega-3 thermogenesis connection, ketones as misfolded protein clearance agents, creatine for depression, retatrutide and PCSK9, BPC-157 risks, and what Dr. Nick Norwitz believes is coming in Alzheimer's gene therapy within the next decade. *Reduce your risk of Alzheimer's with my science-backed protocol for women 30+:*https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ *TOPICS DISCUSSED*(00:00:00) Intro: The ApoE4 Paradox and the Case Report That Broke the Internet (00:00:57) Why Standard Omega-3 Supplements Fail and What to Take Instead (00:05:13) DHA and the Phospholipid Carrier: How It Crosses the Blood-Brain Barrier (00:10:19) ApoE4 Explained: Risk, Genetics, and Why Nick Is Optimistic (00:17:38) Why ApoE4 Carriers Burn Through DHA Faster and Need More (00:20:31) Women, Omega-3s, Menopause, and Brain Insulin Resistance (00:21:41) Statins, Sex Differences, and the DHA-Blood Sugar Connection (00:26:01) Statins and Dementia: What the Data Actually Say (00:32:24) Tau, GSK-3 Beta, Lithium Orotate, and Targeting Alzheimer's Pathology (00:42:19) The Glymphatic System, 40Hz Devices, and Sleep as Brain Clearance (00:45:21) Gene Editing, Prime Editing, and the Future of ApoE4 Therapy (00:49:33) Nick's Case Report: 700 LDL, Zero Plaque, and Seven Years of Data (00:55:10) The EZPAVE Trial: Why the Headlines Don't Hold Up (01:00:33) KetoneIQ: Ketones for Brain Energy and Focus (01:01:29) Cheers Health: Supporting Liver Function and Cognitive Recovery (01:03:54) If Not LDL, What Causes Heart Disease in Metabolically Healthy People? (01:12:05) The Oreo Experiment and the Sardine Diet: Self-Experiments in Metabolism (01:19:10) Ketones, Women's Brains, and Clearing Misfolded Proteins (01:21:08) The Full Brain Health Protocol: Omega-3s, Creatine, NAD, Lithium, and More (01:24:01) GLP-1s for the Brain: Independent of Weight, Targeting Amyloid and Tau (01:25:28) Peptides: BPC-157 Risks, Retatrutide, MOTS-c, and What's Worth Watching (01:29:02) Why Nick Is Controversial And Why He Doesn't Mind _______ *Thank you to our sponsors*Fenix Health Science: fenixhealthscience.com Use code NEUROEXPPulsetto: https://pulsetto.tech/pages/NEURO or use Code NEURO for some off your orderFunction Health: https://www.functionhealth.com/louisanicolaBASED Bodyworks: https://basedbodyworks.com/ and use code NEURO for 20% offKetoneIQ: https://ketone.com/NEURO for 30% OFFCheers Health: https://CheersHealth.com/NEURO or use code NEURO for 20% off _______ I'm Louisa Nicola - clinical neurophysiologist - Alzheimer's prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention.If you're committed to optimizing your brain- reducing Alzheimer's risk - and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0Instagram: https://www.instagram.com/louisanicola_/Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices

He carried two copies of ApoE4, the highest genetic risk factor for Alzheimer's disease, went through medical school knowing exactly what his LDL of 700 meant, decided the experts were wrong, and then published the case report to prove it. In this episode, Louisa sits down with Dr. Nick Norwitz, PhD researcher and metabolic scientist, for one of the most scientifically dense conversations on brain health, cholesterol biology, and Alzheimer's prevention ever recorded on this show. They cover why the phospholipid form of DHA reaches the brain more effectively than standard fish oil, how ApoE4 carriers burn through omega-3s differently and what to do about it, the lithium orotate data that sold out supplement shelves worldwide, and why GSK-3 beta, the enzyme that phosphorylates tau, may be the most under appreciated target in Alzheimer's research today. Then Nick lays out the case that challenges the "LDL is always the enemy" consensus: why metabolically healthy individuals may not benefit from aggressive lipid-lowering therapy, what his viral coronary CT angiogram showed after seven years of 700+ cholesterol, why the EZPAVE trial headlines don't hold up under scrutiny, and what GLP-1s are doing inside the brain completely independent of weight loss. You'll also hear about the sardine diet experiment, the omega-3 thermogenesis connection, ketones as misfolded protein clearance agents, creatine for depression, retatrutide and PCSK9, BPC-157 risks, and what Nick believes is coming in Alzheimer's gene therapy within the next decade. Reduce your risk of Alzheimer's with my science-backed protocol for women 30+:https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ TOPICS DISCUSSED 00:00 Intro: The ApoE4 Paradox and the Case Report That Broke the Internet 00:57 Why Standard Omega-3 Supplements Fail and What to Take Instead 05:13 DHA and the Phospholipid Carrier: How It Crosses the Blood-Brain Barrier 10:19 ApoE4 Explained: Risk, Genetics, and Why Nick Is Optimistic 17:38 Why ApoE4 Carriers Burn Through DHA Faster and Need More 20:31 Women, Omega-3s, Menopause, and Brain Insulin Resistance 21:41 Statins, Sex Differences, and the DHA-Blood Sugar Connection 26:01 Statins and Dementia: What the Data Actually Say 32:24 Tau, GSK-3 Beta, Lithium Orotate, and Targeting Alzheimer's Pathology 42:19 The Glymphatic System, 40Hz Devices, and Sleep as Brain Clearance 45:21 Gene Editing, Prime Editing, and the Future of ApoE4 Therapy 49:33 Nick's Case Report: 700 LDL, Zero Plaque, and Seven Years of Data 55:10 The EZPAVE Trial: Why the Headlines Don't Hold Up 01:00:33 KetoneIQ: Ketones for Brain Energy and Focus 01:01:29 Cheers Health: Supporting Liver Function and Cognitive Recovery 01:03:54 If Not LDL, What Causes Heart Disease in Metabolically Healthy People? 01:12:05 The Oreo Experiment and the Sardine Diet: Self-Experiments in Metabolism 01:19:10 Ketones, Women's Brains, and Clearing Misfolded Proteins 01:21:08 The Full Brain Health Protocol: Omega-3s, Creatine, NAD, Lithium, and More 01:24:01 GLP-1s for the Brain: Independent of Weight, Targeting Amyloid and Tau 01:25:28 Peptides: BPC-157 Risks, Retatrutide, MOTS-c, and What's Worth Watching 01:29:02 Why Nick Is Controversial And Why He Doesn't Mind _______ Thank you to our sponsors Fenix Health Science: fenixhealthscience.com Use code NEUROEXP Pulsetto: https://pulsetto.tech/pages/NEURO or use Code NEURO for some off your order Function Health: https://www.functionhealth.com/louisanicola BASED Bodyworks: https://basedbodyworks.com/ and use code NEURO for 20% off KetoneIQ: https://ketone.com/NEURO for 30% OFF Cheers Health: https://CheersHealth.com/NEURO or use code NEURO for 20% off _______ I'm Louisa Nicola - clinical neurophysiologist - Alzheimer's prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer's risk - and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices

The anti-aging industry is a $59 billion business built on creams, serums, injections, IV drips, and stem cell tourism, and almost all of it is being sold from the outside in, as the actual aging is happening at the level of your DNA, your mitochondria, and the cellular pathways that decide whether your cells protect themselves or wear themselves down over time. Inside today's episode, I walk through the 80/20 breakdown on longevity that most people aren't getting, starting with the identical twin research showing aging is roughly 20% genetic and 80% lifestyle, and the shift in the field from the oxidative stress theory to the current information theory of aging.Topics discussed: - Genetics vs Lifestyle in Aging- The Nine Hallmarks of Aging- The Information Theory of Aging- Sirtuins, AMPK, and mTOR- The Rhythm Between Growth and Repair- Chronological vs Biological Age- Methylation Clocks and Telomere Length- Nutrition, Fasting, and Training Interventions- Sleep, Stress, and Community---------- ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠My Live Program for Coaches: The Functional Nutrition and Metabolism Specialization ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.metabolismschool.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠---------- [Free] Metabolism School 101: The Video Series⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠http://www.metabolismschool.com/metabolism-101⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠----------Subscribe to My Youtube Channel: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://youtube.com/@sammillerscience?si=s1jcR6Im4GDHbw_1⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠----------⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Grab a Copy of My New Book - Metabolism Made Simple⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠---------- Stay Connected: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram: @sammillerscience⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Youtube: SamMillerScience⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Facebook: The Nutrition Coaching Collaborative Community⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠TikTok: @sammillerscience⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠----------“This Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast and the show notes or the reliance on the information provided is to be done at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment and is for educational purposes only. Always consult your physician before beginning any exercise program and users should not disregard, or delay in obtaining, medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions. By accessing this Podcast, the listener acknowledges that the entire contents and design of this Podcast, are the property of Oracle Athletic Science LLC, or used by Oracle Athletic Science LLC with permission, and are protected under U.S. and international copyright and trademark laws. Except as otherwise provided herein, users of this Podcast may save and use information contained in the Podcast only for personal or other non-commercial, educational purposes. No other use, including, without limitation, reproduction, retransmission or editing, of this Podcast may be made without the prior written permission of Oracle Athletic Science LLC, which may be requested by contacting the Oracle Athletic Science LLC by email at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠operations⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@sammillerscience.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. By accessing this Podcast, the listener acknowledges that Oracle Athletic Science LLC makes no warranty, guarantee, or representation as to the accuracy or sufficiency of the information featured in this Podcast."

Send us Fan MailThe facelift internet loves a clean fight: SMAS vs deep plane, one “best” method, one winner. But what if that whole debate is a distraction from the only thing that actually predicts a great result: whether your surgeon can see how faces age in three dimensions and reverse it with intention? I sit down again with Dr. Ben Talei, Beverly Hills facial plastic surgeon, educator, and relentless anatomy nerd, to talk about what technique labels can't capture and why most studies miss the parts patients care about most. We dig into how surgeon “vision” shows up in real outcomes: jawline clarity, midface shape, eye area youthfulness, skin quality, and even how the smile moves after facial rejuvenation surgery. Ben breaks down the logic behind planes, fixation zones, tissue glide, and why “ligament release” has become an oversimplified story that can block real understanding. We also get practical about neck contour, parotid-related volume, and why small three-dimensional corrections can beat big two-dimensional pulls when you're chasing natural, durable change. From there, we go wider: pricing outrage and why elective cosmetic surgery behaves like a luxury market, the ethics of “profiting from insecurity,” and how social media and AI filters are driving unrealistic expectations for facelift results. We close with high-signal rapid fire on what's underrated (nanofat), what's overrated (biostimulators), why fillers can't “defy gravity,” and whether hyperbaric oxygen or light therapy actually helps healing. If you want a clearer way to think about facelift technique, facial aging, and what excellence looks like, this one is for you. Subscribe, share with a friend, and leave a review on Apple Podcasts so more people can find the show.Chapters00:00 Introduction to Dr. Ben Talei06:00 Passion for Cars and Personal Interests10:07 Balancing Education and Practice16:10 The Debate: SMAS vs. Deep Plane Facelifts24:04 Understanding Aging and Surgical Techniques31:41 The Frustration of Misunderstanding in Aesthetic Surgery33:39 The Evolution of Surgical Techniques and Patient Expectations35:59 The Value of Cosmetic Surgery: Price vs. Quality39:18 Addressing Insecurities: The Role of Cosmetic Surgery43:13 The Impact of Social Media and AI on Self-Perception49:29 Advancements in Facial Rejuvenation Techniques56:21 Understanding Facial Anatomy: The Key to Effective Surgery01:00:57 Understanding Surgical Challenges and Techniques01:01:18 The Impact of Crevasse Technique on Aesthetic Surgery01:03:28 Innovative Approaches to Facial Anatomy01:07:23 Exploring the Causes of Aging01:09:09 The Complexity of Aging and Surgical Outcomes01:15:28 The Role of Genetics in Aging01:16:28 Cellular Biology and Aging: A Deeper Dive01:19:12 The Future of Anti-Aging Science01:25:00 Exploring Post-Operative Care Techniques01:29:42 The Efficacy of Light Therapy in Healing01:32:29 Exploring the Efficacy of Anti-Aging Treatments01:33:03 Rapid Fire: Trends in Cosmetic Procedures01:34:46 Underrated and Overrated Anti-Aging Interventions01:35:48 The Importance of Patient Education in Cosmetic Surgery01:37:04 Personal Insights: Balancing Surgery and Self-Care01:37:49 The Intersection of Passion: Cars and Cosmetic Surgery01:38:55 Market Trends in Classic Cars and Investments01:41:05 The Future of Car Values and Investment Strategies01:43:01 The Joy of Car Enthusiasm and Personal ConnectionsDr. Ben Talei Links:Website: https://www.beverlyhillscenter.com/dr-ben-talei/Cupid Lips: https://www.cupid-lips.com/IG: @drbentalei, @muybennoTweet me @realdrhamrahIG @drhamrah

For nearly 150 years, Four Cubs Farms in Grantsburg, Wisconsin, has been built on a simple principle: people matter.In this episode of the Uplevel Dairy Podcast, Peggy Coffeen sits down with Gary and Cris Peterson, their son Ben Peterson, and Dairy Manager Nathan Brandt to explore the leadership, culture, communication, and innovation that transformed a small family dairy into a thriving 1,000-cow operation.From succession planning and employee engagement to genomic testing, feed efficiency, and building trust across generations, this conversation offers valuable lessons for dairy producers looking to create resilient businesses that can thrive well into the future.Whether you're navigating farm transition, building a team, or looking for ways to strengthen your operation's culture, this episode delivers practical insights from a farm that has successfully blended family values with modern dairy management.This episode is sponsored by Compeer Financial. Compeer Financial is a member-owned Farm Credit cooperative serving and supporting agriculture and rural America. Their dairy team brings world-class expertise and tailored solutions to support dairy producers' financial goals and lending needs.02:00 – Growing from 60 cows to 1,000 cows03:00 – Roles and responsibilities within the farm team05:00 – Cris Peterson's journey from city girl to dairy advocate09:00 – Leadership transition and bringing in outside talent10:00 – Nathan Brandt's path into dairy and Four Cubs Farms13:00 – Building a team with complementary strengths14:00 – Innovation through feed systems and grain storage16:00 – Genetics, genomic testing, and future herd growth20:00 – Nutrition strategies for today's high-performing dairy cows24:00 – The role of culture in farm success27:00 – Trust, communication, and employee retention30:00 – Creating clarity, consistency, and rhythm across the operation32:00 – Succession planning, growth, and preparing for the future

Dr. Sharlene Santana is Associate Professor in the Department of Biology at the University of Washington and Curator of Mammals at the University of Washington's Burke Museum of Natural History and Culture. As an integrative and evolutionary biologist, Sharlene explores questions about evolution from a variety of perspectives. She is working to understand why some groups of organisms are more diverse in terms of their number of species, appearance, or behavior. There are over 1,400 species of bats that fulfill a variety of ecological roles, and much of Sharlene's research focuses on diversity in bats. Outside of work, Sharlene loves trying new restaurants in Seattle, as well as traveling to other countries and learning about other cultures. In her free time, you can find Sharlene hiking or swimming with her dog, attending ballet performances, and listening to music and podcasts. She is also a fan of good storytelling in books, movies, TV series, and documentaries. She completed her undergraduate training in biology at the University of the Andes in Venezuela, and she was awarded her Ph.D. in Organismic and Evolutionary Biology from the University of Massachusetts Amherst. Afterwards, Sharlene conducted postdoctoral research at the Institute for Society and Genetics at the University of California, Los Angeles. She joined the faculty at the University of Washington in 2012. In our interview, Sharlene shares more about her life and research.

Brad shares two studies He presented at the American Dairy Science Association annual meeting. First, he examines records from more than 150,000 lactations to compare genetic predictions for somatic cell score and clinical mastitis. The results suggest that PTA for somatic cell score is more useful for predicting and ranking cows by observed somatic cell count than PTA for mastitis.He also discusses a study comparing Holstein and crossbred heifers for feed intake, methane emissions, rumination, and feeding behavior. Although methane produced per kilogram of feed was similar across breed groups, smaller crossbred heifers consumed four to five pounds less dry matter per day. The findings highlight how genetics, breed, sensors, and precision feeding data could help producers improve herd health and heifer management.Questions, comments, scathing rebuttals? -> themoosroom@umn.edu or call 612-624-3610 and leave us a message!Linkedin -> The Moos RoomTwitter -> @UMNmoosroom and @UMNFarmSafetyFacebook -> @UMNDairyYouTube -> UMN Beef and Dairy and UMN Farm Safety and HealthInstagram -> @UMNWCROCDairyExtension WebsiteAgriAmerica Podcast Directory 

From Dysonian SETI to waste heat and galactic timelines, we explore why we haven't found Dyson Spheres—and what their absence reveals about civilization.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurWatch my exclusive video Nearby Supernovae: https://nebula.tv/videos/isaacarthur-nearby-supernovae-could-one-destroy-earth-and-could-we-stop-it

From Dysonian SETI to waste heat and galactic timelines, we explore why we haven't found Dyson Spheres—and what their absence reveals about civilization.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurWatch my exclusive video Nearby Supernovae: https://nebula.tv/videos/isaacarthur-nearby-supernovae-could-one-destroy-earth-and-could-we-stop-it

Thank you for watching!Thanks to Inforgraphics for their wonderful work on a topic that NEEDS more exposure than our channel can give it after being deleted from youtube - please watch their whole video at:https://www.youtube.com/watch?v=EzyLgIGAoQM & Don't forget to like and subscribe - it helps more than anyone knows!~CHECK OUT ALL THE LINKS BELOW FOR THE SYNDICATE & RIOT Co.!https://link.me/breederssyndicate~SUPPORT the channel or JOIN the Discord community: https://www.buymeacoffee.com/matthewriot (This channel is not monetized - any contributions are warmly appreciated & keep us going)~QUALITY GEAR (shirts, stickers, beanies, mugs etc): https://breeders-syndicate-shop.fourthwall.com~PLANT HEALTH & SEX TESTING: https://www.farmerfreeman.com (Coupon Code: SYNDICATE5 )

* Bottom of the 9th: We expect to start delivering hardbound copies of Dr. Walt Brown's "In the Beginning" 9th Edition just before, or just after America's Independence Day celebrations.    * The Knowledge of Good and Evil: This week Fred Williams and Doug McBurney interview Sister Renee Mirkes, Ph.D who reveals the secrets of Napro Technology versus the evils of IVF   * Help Getting Pregnant:  Discover how reproductive specialists and educators have developed ethical fertility treatment that's cheaper and more effective than In Vitro Fertilization, (IVF)   * Help Having a Baby:  Get the information you need to become pregnant and have a baby at Natural Procreation Technology's website right now!   * Sponsor a Show! Go to our store, buy some biblically oriented science material and sponsor a show!   * In The Beginning: Pre-order the 9th edition of Walt Brown's amazing, enlightening, biblically sound book explaining why Earth (and the solar system) look the way they do!   * Sun Puzzles: Check out another one of Ellen McHenry's intriguing and enlightening books: Sun Puzzles - on all the curious facts about the Sun that point to an electric, (and not a nuclear) sun.   * Jesus Light & Design: Get the first in a series of Real Science Radio Teaching Books all about how light and design point to Jesus Christ as the Creator and Savior of the world.

Today on the show, we welcome Genine Coleman to discuss the Legacy Cannabis Genetics: People and Their Plants Research Dissemination Event on June 26, 2026, from 1:30-4:30 PM at the Capital Events Center in Sacramento.  This Free public event will present findings from a first-of-its-kind, multi-year community-based participatory research project examining California's legacy cannabis genetics and the communities that steward them. Funded by Proposition 64 cannabis tax revenues dedicated to public university research, the project brings together researchers from Cal Poly Humboldt, UC Berkeley, the Origins Council, LeafWorks, and the United Core Alliance. It is always an enlightening experience to connect with Genine and I am grateful for her and this work. Genine is the Founder and Executive Director of Origins Council, a nonprofit education, research and policy advocacy organization dedicated to sustainable rural economic development within cannabis producing regions, and establishing nationally and internationally recognized, legally defensible, standards-based, geographic indication systems for cannabis. OC is partnered with regional trade associations based in rural legacy producing regions, and represents the collective membership of these regional partner associations in OC's programmatic activity. Her research interests are focused on community-based participatory research and appellations research. She is currently collaborating with university researchers in California to study California's legacy cannabis genetics and culture. 

What happens when an entire family turns blue... literally? In this Freak Family Favorites episode of The Box of Oddities, Kat and Jethro revisit one of the most fascinating medical mysteries in American history: the legendary Blue People of Kentucky. Deep in the isolated hills of Appalachia, generations of the Fugate family lived with a rare genetic condition that turned their skin shades of blue ranging from pale sky to deep indigo. The story sounds like folklore, but it's completely true. Discover how a chance genetic inheritance, geographic isolation, and a remarkable medical breakthrough created one of the strangest family histories ever documented. Then, the duo travels to the blistering Atacama Desert of Chile to investigate one of the most controversial archaeological discoveries of the 21st century. A tiny six-inch humanoid skeleton with an elongated skull, unusual rib structure, and unsettlingly human features sparked worldwide claims of extraterrestrial life. Was it proof of aliens? A medical anomaly? Or something even stranger? Follow the twists, scientific investigations, DNA testing, and ethical controversies surrounding the mysterious "Atacama Skeleton" and the shocking truth researchers eventually uncovered. From blue-skinned mountain families to alien-looking desert mummies, this episode explores how reality often proves far stranger than fiction. If you love bizarre history, unexplained mysteries, strange science, medical oddities, archaeology, genetics, UFO controversies, and true stories that sound impossible, this is an episode you won't want to miss. #BoxOfOddities #BluePeopleOfKentucky #AtacamaSkeleton #MedicalMysteries #GeneticDisorders #WeirdHistory #StrangeScience #Archaeology #UFOMysteries #Appalachia #TrueOddities #FreakFamilyFavorites Learn more about your ad choices. Visit megaphone.fm/adchoices

Can humanity ever travel faster than light, or does every shortcut through spacetime break causality itself? We explore warp drives, wormholes, tachyons, and why the universe pushes back.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurWatch my exclusive video Nearby Supernovae: https://nebula.tv/videos/isaacarthur-nearby-supernovae-could-one-destroy-earth-and-could-we-stop-it

Can humanity ever travel faster than light, or does every shortcut through spacetime break causality itself? We explore warp drives, wormholes, tachyons, and why the universe pushes back.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurWatch my exclusive video Nearby Supernovae: https://nebula.tv/videos/isaacarthur-nearby-supernovae-could-one-destroy-earth-and-could-we-stop-it

Why did a monk in a Moravian monastery spend eight years counting 30,000 pea plants — and how did the number three to one unlock the secret of heredity that Charles Darwin couldn't solve? Why did Gregor Mendel publish one of the greatest scientific discoveries of the nineteenth century to almost complete silence, only for his paper to be rediscovered thirty-four years later by three scientists who had all independently reached the same conclusion? And how did the statistician who accused him of fraud turn out to have made the statistical error himself?Join John and Patrick as they tell the story of Czechia and the pea — the monastery garden, the number that changed biology, and the 145-year arc from Mendel's first cross-pollination to the Human Genome Project...----------In Sponsorship with J&K Fresh.The customs broker who is your fruit and veggies' personal bodyguard. Learn more here!-----------Join the History of Fresh Produce Club for ad-free listening, bonus episodes, book discounts and access to an exclusive chatroom community.Support us!Share this episode with your friendsGive a 5-star ratingWrite a review-----------Subscribe to our biweekly newsletter here for extra stories related to recent episodes, book recommendations, a sneak peek of upcoming episodes and more.-----------Instagram, TikTok, Threads:@historyoffreshproduceEmail: historyoffreshproduce@gmail.com

For decades, the field focused on the plaques and tangles of misfolded proteins that show up in the brains of patients with Alzheimer's, Parkinson's and other disorders. The natural assumption was that if you could design a drug to clear out that gunk, you could save the brain. But so far, that bet hasn't paid off.Now, researchers are taking a big step back and asking whether the plaques aren't a culprit, but rather a clue pointing to something more fundamental going wrong in our brain cells as we age? Put another way, why do our brains get jammed up with these junk proteins in the first place?Today's guest, chemical engineer and geneticist Monther Abu-Remaileh, is one of the researchers working hard to answer that question. His research goes deep on a tiny cellular structure called the lysosome, little sacs filled with acid and enzymes that break down worn-out proteins and cellular debris. The lysosome is like a sustainable recycling center for a major city, managing waste streams, recycling raw materials, and coordinating with the rest of the cell to keep things running – and when it breaks down, the whole cell starts to fail. Among other accomplishments, Abu-Remaileh, a member of the Knight Initiative for Brain Resilience Steering Committee, has developed clever techniques for probing the lysosome that have put him at the frontier of a transformation in how we think about the lysosome, a transformation that could point the way to slow all manner of neurodegeneration – or even prevent it from happening in the first place.Learn MoreFrom humble beginnings to unlocking lysosomal secrets (ASBMB Today, 2026)‘You can literally lose who you are' (Stanford Report, 2025)Driver of neurodegenerative diseases revealed (Stanford Engineering, 2023)New atlas could help researchers studying neurological disease (Knight Initiative for Brain Resilience, 2026)Sifting through cellular recycling centers (Stanford Engineering, 2022)Lysosomal metabolomics reveals V-ATPase- and mTOR-dependent regulation of amino acid efflux from lysosomes(Science, 2017)CLN3 is required for the clearance of glycerophosphodiesters from lysosomes (Nature, 2022)The Batten disease gene product CLN5 is the lysosomal bis(monoacylglycero)phosphate synthase (Science, 2023)The Bis(monoacylglycero)-phosphate Hypothesis: From Lysosomal Function to Therapeutic Avenues (Annual Review of Biochemistry, 2024)PLA2G15 is a BMP hydrolase and its targeting ameliorates lysosomal disease (Nature, 2025)Cell-type resolved protein atlas of brain lysosomes identifies SLC45A1-associated disease as a lysosomal disorder(Cell, 2026)Send us a text!Thanks for listening! If you're enjoying our show, please take a moment to give us a review on your podcast app of choice and share this episode with your friends. That's how we grow as a show and bring the stories of the frontiers of neuroscience to a wider audience.We want to hear from your neurons! Email us at at neuronspodcast@stanford.eduLearn more about the Wu Tsai Neurosciences Institute at Stanford and follow us on Twitter, Facebook, and LinkedIn. 

In this episode, Dr. Alex Orton shares his journey into holistic health, emphasizing the importance of foundational practices like gut health, lifestyle, and individualized approaches to optimize well-being. Discover key insights on food intolerances, the evolution of gut health strategies, and practical tips for sustainable health improvements.Relevant links:Alex's Website Link: https://havenholistichealth.com/Chapters: 00:00 Introduction and Guest Introduction00:55 Personal Journey into Health and Optimization02:14 Principles of Naturopathic and Holistic Medicine03:52 Core Principles: Do No Harm and Individualized Care06:28 Focus on Gut Health and Its Central Role08:14 Evolution of Gut Health Strategies in Recent Years10:02 Food Intolerance Testing and Its Significance11:46 Understanding IgG vs IgE Food Reactions13:49 Genetics, Ethnicity, and Food Intolerances15:27 Practical Use of Food Intolerance Tests19:25 Personal Insights from Food Testing22:10 Common Pitfalls in Health Optimization24:44 The Role of Hormones and Foundation of Health27:36 High Effort Strategies and Their Impact30:50 Blood Work Analysis and Functional Medicine44:08 Thyroid Function and Its Impact on Health49:52 Holistic Principles: Body's Self-Regulation and Healing52:07 Practical Advice for Health Optimization52:49 Connecting with Dr. Alex Orton and Final ThoughtsDisclaimer:The information provided in this podcast episode is for entertainment purposes and is NOT MEDICAL ADVICE. If you have any questions about your health, contact a medical professional. This content is strictly the opinions of Lucas Aoun and is for informational and entertainment purposes only. It is not intended to provide medical advice or to take the place of medical advice or treatment from a personal physician. All viewers of this content are advised to consult with their doctors or qualified health professionals regarding specific health questions. Neither Lucas Aoun nor the publisher of this content takes responsibility for possible health consequences of any person or persons reading or following the information in this content. All consumers of this content especially taking prescription or over-the-counter medications should consult their physician before beginning any nutritional, supplement or lifestyle program. Hosted on Acast. See acast.com/privacy for more information.

Send us Fan MailToday on Move Daily Talks, I'm joined by Natalie Samson, an integrative board-certified genetic counselor and founder of Golden Genetics.Natalie helps people use genetic information to make more personalized decisions about their health, nutrition, prevention, and longevity. But how much can our genes really tell us? And is genetic testing worth the investment?In this conversation, we're exploring the science behind genetic testing, who may benefit from it, what it can and can't tell us, and how genetics fits into the bigger picture of healthy aging.Let's dive in.Follow Natalie hereGolden Genetics InstagramWebsite4 P Framework QuizJoin Move Daily MembershipFOLLOW ALONG with Move Daily Fitness!Follow on InstagramFollow on FacebookIndemnity** All information provided by Move Daily Fitness and Tracy Steen is of a general nature and is furnished for educational/entertainment purposes only. No information is to be taken as medical or other health advice pertaining to any individual's specific health conditions. Move Daily is not engaged in rendering any medical services. Move Daily makes no guarantee regarding the accuracy, timeliness or relevance of any text, video or audio content. Any content provided is not a diagnosis, treatment plan or recommendation for a particular course of action regarding your health and it is not intended to provide specific medical advice. Do not delay in seeking the advice and diagnosis of a medical professional because of anything you may have read or interpreted from Move Daily Fitness content.  Consult your health care professional before participating in or acting on any recommendations found on Move Daily Fitness.  You agree, at your exposure, to indemnify and hold Move Daily Fitness and Tracy Steen harmless from any and all losses, liabilities and injuries, or damages resulting from and all claims, cause of action, suits, proceedings and demands against Move Daily Fitness and Tracy Steen, arising from or related to decisions or recommendations you make using Move Daily Fitness content. You agree that use of this information is at your own riskIf you love total body workouts, and are looking to increase muscle, this Total Body Split Calendar (follow along video) is for you! Grab yours here today and get started.  The Move Daily Membership is a paid monthly subscription for women, which gives you access to a huge amount of resources to help support you in reaching your health goals. Whether you're looking to lose fat, gain lean muscle, focus on your nutrition, give time to wellness or simply wish to dial in your overall health, we can support you in achieving your objectives. Join today! Shop Legion Supplements and use discount code: MoveDailyThis is an affiliate link.Support the showUse discount code PODCAST10 for a discount on your Move Daily Membership. Don't fade out women, level up!Thanks for moving daily with us in your fitness, wellness and nutrition! Be sure to follow us here:YouTubeInstagramFacebookTikTokSubscribe to my podcast! 

Tfue was the most-watched Fortnite streamer on the planet. Eleven million Twitch followers. Eleven million YouTube subscribers. Over 1.7 billion views. And in 2023, he walked away from it all. Not because he failed. Because he was done. Now he's running 120 miles offshore in the Gulf chasing swordfish, flats fishing in Indian Rocks Beach, and building one of the fastest-growing fishing channels on YouTube under the name C-Few. I really loved this conversation. Some of the moments that stood out to me: - The way Tfue talks about gaming and fishing as two sides of the same obsession — when he's in, he's ALL in. Whether that's streaming 15 hours a day or going 4-for-5 on swordfish before noon. - His take on what it actually takes to be the best in the world at something — genetics, age, reflexes, mindset — and how a lot of it applies far beyond gaming. - The moment he realized a flats boat was too dangerous for anyone he invited on it, and how that pushed him into bigger water and bigger fish. - How he learned sword fishing almost entirely on his own — YouTube, trial and error, and just going 120 miles out into the Gulf until he figured it out. - His honest answer when I asked if competitive gaming and competitive fishing are comparable. He doesn't sugarcoat it. The answer surprised me. 00:00 Introduction 01:00 From #1 Fortnite Streamer to Fisherman 03:35 What It Takes to Be the Best in the World at Gaming 07:00 How Tfue Fell in Love with Fishing 09:45 The Boat Progression — Simmons Flats Boat to 43-Footer 14:00 Sword Fishing the Gulf — Running 120 Miles Offshore 17:00 Sponsors, Growing C-Few, and Building a Fishing Channel 21:00 The Bahamas, Exumas, and Dream Fish 27:30 Retiring at 28 — What That Actually Looks Like 32:00 Gaming vs. Fishing: Competitive Mindset Breakdown 38:00 Fortnite by the Numbers — The Scale Is Hard to Believe 44:00 Enhanced Games, Adderall in Esports, and Performance 51:00 Skill Ceiling, Genetics, and What Makes a Great Competitor 55:00 AI, Chess, and Cheating at the Highest Levels 1:01:00 Dream Catches, Bluefin Tuna, and What's Next 1:07:00 Golf, Card Counting, Casinos, and Random Life Stuff 1:14:00 Where to Find Tfue — Tfue and C-Few

The Nurses Report on America Out Loud with Melissa Schreibfeder, BSN, RN, BC-FMP – Functional pharmacist Michaela Wachal explores how seed oils, genetics, aluminum exposure, and environmental toxins may influence inflammation, detoxification, brain health, and chronic disease risk while highlighting individualized approaches to nutrition, toxicant awareness, and long-term wellness support for families...

The Nurses Report on America Out Loud with Melissa Schreibfeder, BSN, RN, BC-FMP – Functional pharmacist Michaela Wachal explores how seed oils, genetics, aluminum exposure, and environmental toxins may influence inflammation, detoxification, brain health, and chronic disease risk while highlighting individualized approaches to nutrition, toxicant awareness, and long-term wellness support for families...

Join us as as Standing for Truth and Sam team up to debate tag team of 1stAmender and Dr. Ron on whether genetics supports creation or evolution more in this structured 2v2 debate! LINKS TO GUESTS: @StandingForTruthMinistries @1stamender DEBATECON 8 will be in DALLAS on July 25/26th! Grab tickets now! https://events.eventnoire.com/e/debatecon-8-by-modern-day-debate Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

Matters Microbial #132: What 83,000 Generations of Bacteria Reveal About Evolution June 17, 2026 Today Dr. Jeffrey Barrick, John A. Hannah Distinguished Professor of the Department of Microbiology, Genetics, & Immunology and the Department of Entomology at Michigan State University, joins the quality quorum today to discuss how microbes can be used to study evolution itself. He will also discuss the impressive and ongoing LTEE program, the experiments that originate from it, and what they tell us about evolution. Host: Mark O. Martin Guest: Jeffrey Barrick Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode Here is a link to an article about the late great Abigail Salyers. Here is what I wrote about Dr. Salyers. I learned so much from her.  An article about the contributions of Dr. Theodosius Dobzhansky to the study of evolution. The concept of contingency during evolution. An overview of microbial evolution. A link to "Microbes and Evolution," a book discussed during this podcast. A link to "A Primer for Experimental Evolution," a book discussed during this podcast. The concept of Growth Advantage in Stationary Phase (GASP). A video about the MEGA plate experiment by Dr. Michael Baym and colleagues. This is a "must watch." An video about Dr. Richard Lenski, originator of the LTEE. Dr. Lenski's website.  The LTEE (long term evolutionary experiment) website.  There is so much here to explore. An excellent introduction to the LTEE. An article about the amazing " climbing citrate mountain" innovation during LTEE described in the podcast. A video by Dr. Lenski about LTEE. A video by Dr. Barrick that is worth your time. Dr. Barrick's faculty website at Michigan State University. Dr. Barrick's research laboratory website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

Don't miss the free live hydrogen workshop with Kashif. Save your seat at https://midlifeconversations.com/hydrogen  What if every biohack you've tried has been missing the one piece that actually makes it work? Red light, peptides, cold plunges, NAD, wellness IVs. You've tried some of them. Some worked. Some didn't. And here's the maddening part: your friend is thriving on the same protocol that made you feel worse. That's not random, and you're not broken. There's a reason, and it's rooted in your unique biology in ways most practitioners never explain. In this episode, I sit down with Kashif Khan, founder of The DNA Company and someone I genuinely call my health guru. Kashif healed himself from a cascade of chronic conditions including eczema so severe his eye was sealed shut, psoriasis, gut issues, migraines, and depression, all by going deep into functional genomics rather than accepting diagnoses and prescriptions. He now runs what may be the largest functional medicine clinic in the country by volume, working with the most complex cases imaginable. We cover what red light actually does inside your mitochondria and how you can completely overdo it, the real reason peptides cause side effects when used without proper sequencing, why 89% of your cholesterol score has nothing to do with food, and the one molecule Kashif keeps coming back to no matter who the patient is. We also go deep on why hydrogen tablets and bottles are not doing what you think they're doing and what the research actually shows it takes to move the needle. This is one of those conversations that makes you rethink everything. Listen all the way through. WE GO DEEP ON:  Why the same biohack transforms your friend but wrecks you What red light really does inside your cells and how to overdo it Why peptide order matters more than peptide choice Why 89% of your cholesterol score has nothing to do with food Why hydrogen has peer-reviewed studies on every chronic disease Hydrogen tablets vs. breathing: a tablet equals about 20 seconds How to rebuild the 70% of mitochondria you've lost since your 50s Cold plunges, saunas, PEMF, and wellness IVs: what's worth it and what isn't   Catch the full episode on YOUTUBE HERE: https://bit.ly/MidlifeConversationsYouTube   Learn More About Kashif Khan Instagram ➜ https://www.instagram.com/kashkhanofficial  Website ➜ https://midlifeconversations.com/hydrogen    Free Gifts for being a listener of Midlife Conversations! Mastering the Midlife Midsection Guide: https://theflatbellyguide.com/ Age Optimizing and Supplement Guide: https://ageoptimizer.com   Connect with me on social media! Instagram: www.Instagram.com/Nataliejllfit Facebook: www.Facebook.com/Nataliejillfit   For advertising inquiries: https://www.category3.ca/  Disclaimer: Information provided in the Midlife Conversations podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before making any changes to your current regimen.  Information provided in this podcast and the use of any products or services related to this podcast does not create a client-patient relationship between you and the host of Midlife Conversations or you and any doctor or provider interviewed and featured on this show. Information and statements may have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease. Advertising Disclosure: Some episodes of Midlife Conversations may be sponsored by products or services discussed during the show. The host may receive compensation for such advertisements or if you purchase products through affiliate links. Opinions expressed about products or services are those of the host and/or guests and do not necessarily reflect the views of any sponsor. Sponsorship does not imply endorsement of any product or service by healthcare professionals featured on this podcast.  

High blood pressure is one of the most dangerous and overlooked risks in executive health. Not because it's rare, but because the typical lifestyle of entrepreneurs and executives hides it further. You know your revenue, your margins, and your CAC. But there's a reasonable chance you have no idea what your average blood pressure is, or what's actually driving it.In this episode, Julian breaks down seven specific drivers that push blood pressure up in high-level operators, and none of them involve genetics or the tired "avoid sodium" conversation.We also cover why leaders are the last people to catch this, what the numbers actually mean, and the highest-leverage actions to take for each driver. — Episode Chapter Big Ideas (timing may not be exact) —0:00 — Introduction & why blood pressure is the most overlooked number in a leader's life3:16 — Genetics, salt, and why neither is the real conversation5:03 — The scale of the problem: the global hypertension picture 7:33 — Why leaders are the last to notice their own biological signals10:03 — The "I'm fine" trap and why functioning isn't the same as thriving11:43 — Driver 1: Sleep Apnea18:12 — Driver 2: Visceral Fat22:14 — Driver 3: Insulin Resistance27:29 — Driver 4: Chronic Stress & Sympathetic Overdrive32:51 — Driver 5: Alcohol36:47 — Driver 6: Poor Sleep42:33 — Driver 7: Arterial Stiffness & Vascular Aging47:05 — The Executive Biological Dashboard51:06 — Closing: health and fitness as the ultimate meritocracy— Connect with Julian and Executive Health —LinkedIn — https://www.linkedin.com/in/julianhayesii/X — https://x.com/thejulianhayesDon't let your biology become the bottleneck to the enterprise you're building. Book a private call —https://www.executivehealth.io/contactWebsite — https://www.executivehealth.io/***DISCLAIMER: The information shared is not meant to treat or diagnose any condition. This is for educational, informational, and entertainment purposes. The content here is not intended to replace your relationship with your doctor and/or medical practitioner. Consult your provider before making any decisions.

What Causes Cancer? The Truth Most Doctors Don't Talk AboutIn this episode of Intellectual Medicine, Dr. Stephen Petteruti explores the relationship between cancer, metabolism, sugar, insulin, body fat, and prostate cancer progression. He discusses the Warburg theory, which suggests that cancer may begin with dysfunctional mitochondrial metabolism, and compares it with the later focus on genetic causes of cancer. While he argues that the idea of “starving cancer” by eliminating sugar is too simplistic, he also emphasizes that metabolic health plays a real role in cancer risk and progression.The episode focuses heavily on prostate cancer, which Dr. Petteruti describes as unique compared with other cancers. He argues that conventional approaches often overlook the environment in which cancer develops, including excess body fat, high insulin, elevated blood sugar, inflammation, and poor metabolic health. He also discusses tests such as fasting insulin, hemoglobin A1c, and continuous glucose monitoring, as well as the importance of nutritional and behavioral change. The episode closes with a warning against extreme diets, oversimplified supplement advice, and one-size-fits-all cancer theories.Timestamps:(00:00) What Causes Cancer?(01:02 )The Warburg Theory(02:14) Genetics vs. Metabolism(04:22) Why “Starving Cancer” Is Too Simplistic(05:42) Body Fat, Insulin, and Prostate Cancer(08:30) Tests That May Help Assess Metabolic Health(10:47) Food, Weight Loss, and Cancer Risk(13:42) The Anti-Cancer Lifestyle(15:04) Toxins, Viruses, and Parasites(16:15) NAD, Mitochondria, and Supplement Caution(17:33) Growth Hormone, IGF-1, and Cancer Risk(19:12) Why Extreme Dieting Is Not the AnswerEnjoy the podcast? Subscribe and leave a 5-star review on your favorite platforms.Dr. Stephen Petteruti is a board-certified physician specializing in longevity-focused, integrative medicine. He works with men navigating prostate cancer, testosterone, and hormone health, aging, and performance using proactive, evidence-informed strategies grounded in real clinical practice. His approach prioritizes preserving function, strength, and quality of life while helping patients make clear, informed decisions beyond reactive, fear-driven care.Book: Fight Cancer Like a Man: https://tinyurl.com/FightLikeAManBookDr. Steve's email newsletter: https://drstephenpetteruti.substack.com/subscribePodcast show notes : https://www.intellectualmedicine.com/podcast-notesMember exclusive content: https://tinyurl.com/DrPetterutiMemberLearn more: https://www.drstephenpetteruti.com/ Learn more: https://www.intellectualmedicine.com/ Connect with Dr. Petteruti on:⁠Instagram: ⁠https://www.instagram.com/dr.stephenpetteruti/⁠ Facebook: ⁠https://www.facebook.com/dr.stephenpetteruti⁠ Disclaimer:The content presented in this video reflects the opinions and clinical experience of Dr. Stephen Petteruti and is intended for informational and educational purposes only. It is not medical advice and should not be used as a substitute for professional diagnosis, treatment, or guidance from your personal healthcare provider. Always consult your physician or qualified healthcare professional before making any changes to your health regimen or treatment plan.

Dr. Ashok K. Shetty is a University Distinguished Professor in the Department of Cell Biology and Genetics and Associate Director of the Institute for Regenerative Medicine at Texas A&M University, Naresh Vashisht College of Medicine. He is developing treatments for neurological and neurodegenerative disorders using stem cells and stem cell-derived products, such as extracellular vesicles. These are tiny vesicles secreted by stem cells that carry microRNAs and proteins. Once they make their way into the brain, they can induce beneficial changes in neural cells to improve brain function. Science takes up a lot of Ash's time, but when he's able to get a moment to himself, he enjoys spending time with family, cycling on a stationary bicycle, playing brain games like Sudoku, and going out to see movies at the theater. Ash earned his Ph.D. in Neuroscience from the All India Institute of Medical Sciences in New Delhi, and he completed postdoctoral research at Montana State University and Duke University. Afterward, he joined the faculty at Duke University in the Division of Neurosurgery. He joined the faculty at Texas A&M University College of Medicine in 2011. In 2024, he was honored with the University Distinguished Professor Award from Texas A&M University, and he has also received the College of Medicine's Senior Research Excellence Award. In addition, Ash is a Fellow of the American Association for the Advancement of Science and the American Society for Neural Transplantation and Repair. He has received the Research Career Scientist Award from the United States Department of Veterans Affairs, has been recognized among the "World's Top 1% of Scientists" across all scientific fields, and he was the 2025 honoree of Fast Company's World Changing Ideas. In this interview, Ash shares details about his life and his work in science.

Meaghan Doyle is a genetic counsellor at Markham Fertility Centre in Ontario, Canada, specializing in infertility, preimplantation genetic testing, and preconception genetic counselling. After seeing patients who came from other clinics where access to a genetic counsellor was not available, she saw the negative impact this had on their care. She has since joined Instagram to help provide education on fertility genetics to help bridge this gap. Meaghan is passionate about genetics, and works together with patients so they can feel empowered to make decisions about their fertility treatment that are best for them. I'm delighted to have her join me on the podcast today to discuss mosaic embryos, genetics, and your fertility. We are going to discuss the success rates of transferring mosaic embryos, understanding the different rankings of mosaic embryos, and the misconceptions about mosaics. Listen on Dr. Aimee's website  Subscribe to my YouTube channel for more fertility tips!  Join Egg Whisperer School Checkout the podcast Subscribe to the newsletter to get updates  Dr. Aimee Eyvazzadeh is one of America's most well known fertility doctors. Her success rate at baby-making is what gives future parents hope when all hope is lost. She pioneered the TUSHY Method and BALLS Method to decrease your time to pregnancy. Learn more about the TUSHY Method and find a wealth of fertility resources at www.draimee.org.

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Can a human being's behavior and personality be fully explained by a machine, chemistry, biology, or data? Or is there something intangible left over?These questions and the different conversations they can spark were the inspiration behind this special episode of A Book with Legs. Smead Capital Management CEO and Portfolio Manager Cole Smead revisits highlights from conversations with experts offering unique perspectives on the topic, including a computer scientist, a geneticist, a neuroscientist, and a cognitive scientist.Check out the full episode to hear from names like Paige Harden, author of "Original Sin: On the Genetics of Vice, the Problem of Blame, and the Future of Forgiveness" and Charles Murray, author of "Taking Religion Seriously." Smead Chairman and CIO Bill Smead also shares his perspective on what past manias have had in common and why those lessons remain relevant for investors today.Sign up to be notified about new episodes: https://hubs.ly/Q0452Lh70 #ABookwithLegs#PlayTheLongGame #AI #History #Science

Thank you for watching!~CHECK OUT ALL THE LINKS BELOW FOR THE SYNDICATE & RIOT Co.!https://link.me/breederssyndicate~SUPPORT the channel or JOIN the Discord community: https://www.buymeacoffee.com/matthewriot (This channel is not monetized - any contributions are warmly appreciated & keep us going)~QUALITY GEAR (shirts, stickers, beanies, mugs etc): https://breeders-syndicate-shop.fourthwall.com~PLANT HEALTH & SEX TESTING: https://www.farmerfreeman.com  (Coupon Code: SYNDICATE5 ) 

Explore the future of space habitats, from rotating cylinders and torus colonies to orbital cities, asteroid homes, and the megastructures humanity may one day live inside.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurWatch my exclusive video Nearby Supernovae: https://nebula.tv/videos/isaacarthur-nearby-supernovae-could-one-destroy-earth-and-could-we-stop-it

Explore the future of space habitats, from rotating cylinders and torus colonies to orbital cities, asteroid homes, and the megastructures humanity may one day live inside.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurWatch my exclusive video Nearby Supernovae: https://nebula.tv/videos/isaacarthur-nearby-supernovae-could-one-destroy-earth-and-could-we-stop-it

Dr. Riley Kirk welcomes Dr. Anna Schwabe to the Bioactive Podcast for a deep dive into cannabis genetics, cultivar identity, plant chemistry, and the challenges of making sense of cannabis in a rapidly evolving industry. As two cannabis scientists get thoroughly nerdy, they explore the relationship between genetics and chemical expression, why cultivar names matter, and what science can and cannot tell us about predicting cannabis effects. Drawing from years of research in cannabis genomics, chemotypes, and consumer behavior, Anna explains the disconnect between strain names, marketing claims, and actual genetic identity. The conversation examines how genetics, environment, cultivation practices, and post-harvest handling influence the final chemistry of a cannabis product, often making consumer expectations difficult to predict. They also explore the limitations of the indica, sativa, and hybrid framework, discussing why these categories may still serve a purpose for new consumers while highlighting the need for more nuanced approaches to cannabis classification. The discussion dives into terpene science, aroma-based selection, cultivar verification, consumer perception, breeding strategies, and the future of genetic authentication in cannabis. Additionally, Riley and Anna tackle common industry misconceptions, the importance of preserving cannabis history and culture, and how science can help bridge the gap between growers, consumers, researchers, and retailers. Throughout the episode, they emphasize practical ways consumers can make better decisions while exploring the fascinating complexity of cannabis chemistry and genetics. Whether you're a grower, breeder, budtender, researcher, medical patient, or curious consumer, this episode offers valuable insights into how cannabis genetics shape the products we use and the experiences we have. CHAPTERS: 00:00 Podcast Crossover Intro 01:38 New Mom Conference Life 02:32 Cannabis on Social Media 03:59 Schedule III Debate 06:36 Pharma Versus Whole Plant 10:08 Synthetic THC And Isomers 12:26 Terpenes And Aroma Complexity 16:51 When More Is Not Better 19:27 Realistic THC And Terp Limits 22:56 Trust Your Nose Shopping 24:47 Why Blue Dream Varies 25:44 Genetics Registration And Terroir 29:23 Consistency Versus Craft Growing 33:12 Craft Cannabis Value 34:25 Does Quality Mean Less 35:48 Savoring Premium Products 38:33 CHS And Overconsumption 42:33 Allergens Terpenes Perfume 45:03 Pregnancy Smell Sensitivity 47:05 Trust Your Nose Shopping 50:44 Beyond Indica Sativa 54:24 Strain Names Still Matter 57:32 Genome Gaps Landraces 59:43 New Compounds Plant Evolution 01:01:24 Overmanipulated Modern Nugs 01:03:16 Potency And Oversized Joints 01:04:42 Right Sizing Your Dose 01:05:46 Type Two Flower Wins 01:06:29 Budtenders Versus Medical Advice 01:08:35 Research Weed Supply Problem 01:12:42 Study Real Dispensary Products 01:14:08 What Consumers Actually Want 01:16:12 True Cut Genetic Verification 01:17:48 IP Protection And Licensing 01:19:05 Finding Medicine By Genetics 01:21:09 Scaling The Sample Universe 01:25:59 AI Guided Breeding Future 01:27:05 Where To Follow And Next Steps 01:27:36 New Work In Houston 01:29:19 Riley Projects And Wrap Up Connect with Dr. Anna Schwabe: Website: www.annaschwabe.com LinkedIn: https://www.linkedin.com/in/anna-schwabe-phd/ True Cut Bioscience: https://www.truecut.co/ Agricultural Genomics Foundation: https://agriculturalgenomics.org/ MyFlora DNA: https://myfloradna.com/ Want Exclusive Content and Ad-Free Episodes? Join the Bioactive Patreon community for as little as $1/month to ask guests your burning questions, access exclusive content, and connect with Dr. Kirk one-on-one. www.Patreon.com/Cannabichem Don't forget to like, subscribe, and hit the notification bell for more conversations on cannabis science, genetics, plant biology, cultivation, pharmacology, and emerging research. Sign Up for Emails: www.AppliedPharmacognosy.org Keep up with Dr. Riley Kirk: https://www.bioactivepodcast.com/ https://www.youtube.com/@cannabichem https://instagram.com/cannabichem https://www.appliedpharmacognosy.org/ Learn more about your ad choices. Visit megaphone.fm/adchoices

What if fusion power never becomes practical? Humanity still has solar, fission, storage, beamed power, and enough known physics to build a spacefaring future.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurWatch my exclusive video Nearby Supernovae: https://nebula.tv/videos/isaacarthur-nearby-supernovae-could-one-destroy-earth-and-could-we-stop-it

What if fusion power never becomes practical? Humanity still has solar, fission, storage, beamed power, and enough known physics to build a spacefaring future.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurWatch my exclusive video Nearby Supernovae: https://nebula.tv/videos/isaacarthur-nearby-supernovae-could-one-destroy-earth-and-could-we-stop-it

At Lifespan, our mission is to help you and your loved ones live your longest, healthiest lives while supporting medical research into breakthroughs to improve all lives. We're building the world's largest longevity community: Join us at https://lifespan.com. Follow us on YouTube, Apple, and Spotify for new Lifespan episodes every 2 weeks.                               __________________________________________ In this first episode of Lifespan Season 2, Dr. David Sinclair, A.O., Ph.D. - Professor of Genetics at Harvard Medical School and pioneer in longevity research - returns and explores one of the most consequential questions in science: How can aging be slowed or reversed? Drawing on more than 25 years of research at the forefront of aging biology, Dr. Sinclair explains why humanity has entered a revolutionary period. Advances in science and technology have converged and transformed aging into a promising target for intervention. This episode is a sweeping introduction to the science, breakthroughs, and emerging technologies that are fundamentally reshaping how we think about aging, disease, and the future of human health.                                __________________________________________ Partners of the Lifespan show help us keep this program freely available as an educational resource while also supporting medical research. We only collaborate with partners whose products are grounded in science and that our team has personally used for years. Our selected partners make it convenient for the Lifespan audience to access the tools and technologies featured in this episode - from exogenous fuel for neurons (Ketone-IQ), to wearables that track recovery, strain, and sleep (WHOOP), to smart devices that measure key health metrics such as visceral fat and muscle mass (Withings). If you'd like to learn more or try these tools: ○ Ketone-IQ: Get 30% off your first monthly order at https://ketone.com/lifespan or with code LIFESPAN ○ WHOOP: Get a free WHOOP band and one month of membership at https://join.whoop.com/LIFESPAN or with code LIFESPAN ○ Withings: Get 10% off smart health devices at https://withings.com/lifespan or with code LIFESPAN                                __________________________________________ Legal & Medical Disclaimers The Lifespan show and all related content are provided for informational and educational purposes only and are not intended as medical advice, diagnosis, or treatment. Nothing presented should be interpreted as a recommendation to diagnose, treat, cure, or prevent any disease or medical condition. This content is not a substitute for professional medical advice, diagnosis, or treatment from a qualified healthcare provider. You should always consult with a licensed physician or other qualified healthcare professional before making decisions about your health, including starting, stopping, or modifying any treatment, supplement, diet, or exercise program. The information shared reflects the views and opinions of the host and guests and is based on the scientific literature, their experience and expertise, and general wellness principles. Listening to or engaging with Lifespan content does not establish a doctor–patient or clinical relationship.  Health and longevity outcomes can vary significantly between individuals. Any references to studies, interventions, products, or protocols are not guarantees of specific results, and individual responses may differ. From time to time, Lifespan may discuss or partner with third-party products or services. These references are provided for informational purposes only and should not be considered medical recommendations or endorsements of efficacy for any individual. Lifespan Foundation is an independent 501(c)(3) non-profit organization whose mission is to support medical research.   The views expressed by Dr. David Sinclair, A.O., Ph.D., are his own and do not represent those of Harvard University, Harvard Medical School, or any affiliated institutions.