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This episode covers Turner syndrome.Written notes can be found at https://zerotofinals.com/paediatrics/genetics/turner/Questions can be found at https://members.zerotofinals.com/Books can be found at https://zerotofinals.com/books/The audio in the episode was expertly edited by Harry Watchman.
In this solo episode of The SuperLife Podcast, Darin Olien dives deep into the true biology of energy—not motivation, not stimulants, not willpower, but the mitochondria themselves. Inspired by a groundbreaking conversation between Dr. Andrew Huberman and Dr. Martin Picard, Darin reframes energy as an emergent property of how we live, not just what we eat or how much we sleep. This episode explores how mitochondria act as signal translators, listening to your food, stress, sleep, movement, emotions, purpose, and environment—and turning those signals into either vitality or depletion. Darin connects cutting-edge mitochondrial science with real-world practices around recovery, meaningful stress, consistency, connection, and alignment, showing how true longevity and resilience are built at the cellular level. What You'll Learn in This Episode 00:00 – Welcome to SuperLife & the mission of sovereignty and vitality 00:32 – Thera Sage sponsor: family-built healing tech & red light 02:10 – Why this episode is different: diving into cellular energy 02:42 – Inspiration from Huberman & Picard's mitochondria conversation 03:11 – Rethinking mitochondria: not just ATP, but information processors 04:03 – Energy as potential for change, not calories or fuel 04:39 – How thoughts, emotions, food, and stress shape energy 05:05 – Energy is dynamic, adaptive, and responsive to how you live 06:02 – Mitochondria as signal integrators: sleep, hormones, purpose, connection 06:50 – Mitochondria as antennas, not factories 07:16 – Translating life experience into biological energy 08:09 – Why we don't feel "energy," we feel energy flow 08:53 – Flow states, purpose, and why passion creates vitality 09:32 – Different organs, different mitochondrial roles 10:26 – Why energy optimization is not one-size-fits-all 10:49 – Energy resistance: the hidden cause of fatigue and burnout 11:47 – Chronic stress, poor sleep, and ultra-processed food as energy blockers 12:12 – Why recovery is non-negotiable for longevity 12:20 – Caldera Lab sponsor: clean, performance-driven skincare 14:20 – The danger of constant output without recovery 14:45 – Sleep as a mitochondrial reset and repair system 15:40 – Exercise, adaptation, and why recovery completes the signal 16:22 – Intentional stress vs. chronic stress 17:29 – Food as information, not just fuel 18:05 – Time-restricted eating, fresh food, and metabolic signaling 18:27 – Meaning, purpose, and emotional states as cellular inputs 19:23 – Mitochondria, aging, and the potential reversibility of decline 20:06 – SuperLife framework: alignment over optimization 20:37 – Consistency beats intensity at the cellular level 21:19 – Stable rhythms: sleep, nourishment, hydration, movement 21:45 – Stillness, meditation, and parasympathetic repair 22:35 – Growth requires both resistance and recovery 24:44 – Connection, community, and loneliness as biological signals 25:27 – Eliminating fatal conveniences to restore vitality 26:02 – Your mitochondria are listening—change the signals 26:21 – Honoring Huberman & Picard's contribution to human health 27:12 – Energy flow as the foundation of a SuperLife 28:11 – Closing reflections and invitation to apply this work Thank You to Our Sponsors Therasage: Go to www.therasage.com and use code DARIN at checkout for 15% off Caldera Lab: Experience the clinically proven benefits of Caldera Lab's clean skincare regimen and enjoy 20% off your order by visiting calderalab.com/darin and using code DARIN at checkout. Join the SuperLife Community Get Darin's deeper wellness breakdowns — beyond social media restrictions: Weekly voice notes Ingredient deep dives Wellness challenges Energy + consciousness tools Community accountability Extended episodes Join for $7.49/month → https://patreon.com/darinolien Find More from Darin Olien: Instagram: @darinolien Podcast: SuperLife Podcast Website: superlife.com Book: Fatal Conveniences Key Takeaway "Your mitochondria are not broken. They are responding perfectly to the signals you give them. Change the signals, and your energy, resilience, and life will follow." Bibliography & Sources Here is the bibliography based on the sources referenced in the document, formatted with direct links to the scientific papers, books, and the podcast episode. Primary Source Material Huberman, A. (Host). (2025, December 15). Improve Energy & Longevity by Optimizing Mitochondria with Dr. Martin Picard [Audio/Video podcast]. Huberman Lab. Link to Episode Picard Lab. Mitochondrial Psychobiology Group. Columbia University Irving Medical Center. Link to Lab Website Key Scientific Literature & Books Hood, D. A., Memme, J. M., Oliveira, A. N., & Triolo, M. (2019). Exercise and Mitochondrial Biogenesis. Physiological Reviews, 99(1), 669–715. Read Study Lane, N. (2015). The Vital Question: Energy, Evolution, and the Origins of Complex Life. W.W. Norton & Company. Book Link López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M., & Kroemer, G. (2013). The Hallmarks of Aging. Cell, 153(6), 1194–1217. Read Study Mattson, M. P., Moehl, K., Ghena, N., Schmaedick, M., & Cheng, A. (2018). Intermittent Metabolic Switching, Neuroplasticity and Brain Health. Nature Reviews Neuroscience, 19, 63–80. Read Study Picard, M., & McEwen, B. S. (2018). Psychological Stress and Mitochondria: A Systematic Review. Psychosomatic Medicine, 80(2), 126–140. Read Study Picard, M., & Shirihai, O. S. (2022). Mitochondrial Psychobiology: Foundations and Applications. Current Opinion in Behavioral Sciences, 43, 102–110. Read Study Speakman, J. R., & Selman, C. (2011). The Free-Radical Damage Theory: Accumulating Evidence Against a Simple Link. Trends in Ecology & Evolution, 26(1), 33–39. Read Study Wallace, D. C. (2015). Mitochondria and Cancer. Nature Reviews Cancer, 12, 685–698. (Note: Often referenced alongside his Annual Review of Genetics work on aging). Read Study
(00:00-43:13) Not a best of, but let's make it one. Third shifters. Text in if you're armed and pissed. Barge Guy is back. Shout out everybody on the river. What's the Christmas meal for the boys on the barge? River's low. Alright, thank you Bargie. Uncle Rich tackled a cardboard cutout once thinking it was an intruder. Jackson's Christmas 'stache. Bring back the handlebar mustache. Journalism is what moves the nation. Bofa Deez is on the line. Bofa has been emotionally sick. The new wife left too. Maybe just stay single for a while. Porch pirates. Genetics you know, what a story.(43:21-52:54) Down on barbershop quartets. Mailboxes are federal property. Candy Cane Lane. Take heists. Is Tim safe? Daniel Stern. Lotta unhappy Mizzou basketball fans.(53:04-1:08:27) Michigan J Frog. JR is in studio soliciting non perishable food items. Martin was locked out this morning. JR is here to save the show. Working for the Suburban Journals back in the day and covering youth sports. Weird JeffCo kinks. Taking over on the Blues beat back in 05. Going to college bars.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In this episode, Datis Kharrazian bridges complex science with practical strategies you can use right away, focusing on the fascinating concept of biological age versus chronological age.You'll learn why some people seem to age slower or faster than their years might suggest, and discover how factors like sleep, fasting, diet, and resilience are key to longevity and vibrant health. Datis Kharrazian dives into personalized clinical models, exploring mechanisms such as inflammation, cellular senescence, and genetic influences—and explains why resilience is the central feature in successful aging, healthspan, and overall wellness.Whether you're a healthcare professional looking to advance your functional medicine expertise or someone seeking effective strategies for chronic health challenges, this episode lays the groundwork for integrating functional medicine and geroscience into everyday practice. Learn functional longevity strategies from Dr. Datis Kharrazian. Discover how to use personalized nutrition, diet, and lifestyle approaches to optimize healthspan. Enroll in the Longevity Mastery Program at: https://pages.kharrazianinstitute.com/longevityFor patient-oriented functional medicine courses, visit https://drknews.com/online-courses/For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/00:00 "Biological vs. Chronological Age"04:25 "Inflammaging and Cellular Health Strategies"08:49 "Resilience: Key to Longevity"12:03 "Intermittent Fasting and Longevity"13:00 "Longevity Research and Key Pathways"19:25 "Genetics and Resilience in Aging"21:03 "Resilience: Key to Healthy Aging"23:23 "Enhancing Resiliency Through Geroscience"27:39 "Inflammatory Resiliency and Intolerances"30:40 "Geroscience: Aging and Resilience"Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.
In this episode of Shift with CJ, I sit down with Dr. Ebenezer Abel Paul, founder of Verve Wellness Dubai, to break down one of the biggest questions in health and longevity: If our genes are fixed, why are we all so different—and how much control do we really have?We take genetics out of the abstract and bring it down to first principles. Why some people tolerate carbs better. Why others struggle with dairy, stress, or weight. Why environment, culture, and modern city life (especially Dubai) can either switch on disease or unlock performance.Dr. Ebenezer explains genetics in a practical way: Your genotype is your blueprint. It doesn't change. Your phenotype—how those genes express—is shaped by lifestyle, food, sleep, stress, environment, and decisions made daily.We dive into why “it runs in my family” is often a misunderstanding of lifestyle patterns rather than destiny, using examples like type 2 diabetes, lactose intolerance, obesity risk, and stress sensitivity. The episode also explores how modern stress, poor sleep, ultra-processed food, eating out culture, microplastics, EMFs, and vitamin deficiencies silently alter gene expression.We discuss the Well Gene Book as an entry point into personalized medicine—not as a diagnosis tool, but as a lifelong blueprint to make better decisions. Dr. Ebenezer explains why combining genetics with blood work, gut health, proteomics, and lifestyle data creates true precision health—and why random supplements, generic diets, or self-diagnosing with AI can backfire.The future, according to Dr. Ebenezer, is not shortcuts—but data harmonization: genetics + lifestyle + environment + AI-guided decision-making, all personalized to the individual.Key TakeawaysGenetics load the gun, lifestyle pulls the trigger.Most “genetic diseases” are actually lifestyle-driven expressions.Modern city life creates a mismatch between biology and environment.Food intolerances often show up as fatigue, brain fog, skin issues—not just gut symptoms.Personalized health beats generic diets, workouts, and supplements every time.5 Things You Can Start Doing TodayStop copying diets — eat based on how you respond, not influencers.Question symptoms like bloating, fatigue, brain fog—they're signals, not normal.Fix sleep first — poor sleep amplifies stress genes and inflammation.Reduce eating out — unknown oils, reheated food, and plastics matter.Use data wisely — genetics guide decisions, blood work confirms reality.Knowledge doesn't remove responsibility—it gives you control.
This episode features Dr. Jocelyn Johnson with STgenetics, a speaker at the 2025 ADSA Breeding and Genetics Symposium: Creating Carbon-Friendly Cows and Leveraging Omics to Improve the Sustainability of Dairy Production.Dr. Johnson's presentation was titled “Advancing dairy sustainability through feed-efficient genetics and genomics: Research insights and applications.” She gives an overview of her talk, which focused on data STgenetics has collected and how the company has applied that data to help their customers be more sustainable. She goes on to describe some of the residual feed intake research they've conducted in dairy cows. (4:20)STgenetics has invested in feed efficiency technology and has shown that selection for improved feed efficiency is correlated to a lower carbon footprint. Dr. Johnson talks about the heritability of feed efficiency compared to other traits we select for in the dairy industry. (8:16)Dr. Pralle asks Dr. Johnson if STgenetics is measuring emissions from cows in their research. The company has partnered with Texas A&M to measure methane emissions in heifers divergently selected for feed efficiency. They found that more efficient animals produced less methane. Since that pilot project, STgenetics has purchased equipment to measure emissions at their own research facilities and has collected 2-3 years of data on beef, beef on dairy, and Holstein populations. Dr. Johnson emphasizes that the relationship between methane emissions and high milk production is somewhat of a balancing act. (11:29)The group discusses feed additives purported to decrease methane emissions and the differences in rumen microbiomes between high and low efficiency animals. They also talk about how best to get information and technology in front of producers. (17:59)Panelists share their take-home thoughts. (23:39)Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table. If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.
In this episode, recorded live at the World Dairy Expo, Peggy sits down with Tim Baumgartner, the genetics manager at Jer-Z-Boyz Ranch in Pixley, California. Tim shares his journey from growing up on a dairy farm in Wisconsin to becoming a pivotal figure in the dairy genetics industry. He discusses his passion for cows and people, recounting how one pivotal conversation led to a rewarding career in genetics. The episode explores how the Jer-Z-Boyz Ranch significantly improved the breed's genetics, the impact of mentorship, and how innovative technology, like the Milc Group's feed program, transformed their operations. Highlights include the discovery and development of high-fat Jersey cows, the challenge and success of polled genetics, and the importance of family and community in the dairy world. Tim's story is a testament to resilience, passion, and the pursuit of excellence in the dairy industry.This Episode is Brought to you by Milc GroupMilc Group is a dairy software company that brings real-time, actionable data to dairy farms across the world. They are dedicated to revolutionizing the dairy industry with their user-friendly cloud-based software. ONE™ by Milc Group is our all-in-one app that brings together all the important aspects of your dairy together in one place. With products such as feed and animal management software, people training, dairy facility monitoring, and scale management, Milc Group is committed to providing producers with the tools they need to succeed.ONETM Feed: https://www.milcgroup.com/product/feedONETM Scale: https://www.milcgroup.com/product/scale00:00 Introduction: Shaping a Breed and Leaving a Legacy00:07 Meet Tim Baumgartner: A Passion for Genetics01:23 Growing Up on a Dairy Farm in Wisconsin07:42 The Journey to California09:31 A Career in Genetics and Mentorship15:37 The Jer-Z-Boyz Ranch Transformation27:39 Innovations and Future Directions
Conversation with Joe Messer starts at 2:20. California Spring Trials 2026: March 24-27 (Days and time may vary by location.) https://caspringtrials.us/ Tech On Demand host (and 20-year trials veteran) Bill Calkins collaborated with California Spring Trials registration managers at National Garden Bureau to produce a series of podcasts featuring representatives from just about every exhibiting company in an effort to get you excited about the iconic industry event and some of the new plant introductions you'll see on display in spring of 2026. California Spring Trials is the horticulture industry's “fashion week” and with more than two dozen participating companies bringing hundreds of new plants to market for 2027 and beyond, opportunities to get inspired and plan new additions to your crop mix abound! Registration for this annual even is essential to help hosts create an amazing, customized experience for all attendees. REGISTER FOR CAST 2026 NOW AT https://caspringtrials.us/. You'll also find a trip planner, location information and more. Be sure to schedule plenty of time at each stop and with each exhibiting company!
Send us a textSubscribe and unleash your inner science goblin. We see you. We respect it.DNA isn't magic—but it is one of the most powerful instruction systems in the universe.In this deep-dive episode of Wildly Curious, Katy Reiss and Laura Fawks Lapole break down genetics, DNA, and inheritance in a way that actually makes sense—no lab coat required. From the tiny molecular code inside your cells to the ethical questions surrounding modern gene editing, this episode connects the science to real life.
A conversation with Dr. Andrés Moreno Estrada We are honored to share a compelling conversation with Dr. Andrés Moreno Estrada, a renowned geneticist whose work is transforming how we understand human diversity, ancestry, and health. In [...]
The Heart of Tradition Podcast- For everything magnesium but also life changing ideas, European wisdom, health tips and more from the speartip!ALSO: Goodbye Industrial Grade Magnesium claiming to be Zechstein. Hello Clear-stone, Zero Solvent Magnesium !! Can you call the source? With us you can.Always in healthy blue GLASS. Only One Ingredient. Verifiable Zechstein.For our videos check out our website. Click on Videos. OR for our Blog, Click on Blog.20% off with code HEART20 theheartoftradition.com
The Idaho State Department of Agriculture (ISDA) recently led an agricultural trade mission to Vietnam.
Any comments/questions?https://x.com/iamdanielfordHumanity is heading fast towards a human-AI fusionIn this episode...The parent company of Sky is in talks to buy ITV's broadcasting business for about £2bn, in a move that would upend the British television landscape. Media ownership is in the hands of ever fewer people, but why? It's not just about moneyThe founder of ChatGPT, Sam Altman, is backing a controversial genetic engineering startup that aims to eliminate hereditary diseases from babies. Where is the gathering focus on synthetic biology and genetic editing planned to end?...Scientists issue ominous warning over mind-altering 'brain weapons' that can control your perception, memory and behaviourAnd finally, the leading vaccine regulator at the Food and Drug Administration (FDA) has announced a far stricter course for federal vaccine approvals, following claims from his team that Covid vaccines were linked to the deaths of at least 10 children.
Apply to join AFM here00:00 Introduction to Lydia's Journey02:25 The Shift from Corporate to Coaching05:33 Defining Hustle vs. Hard Work08:16 Understanding Enough and Abundance10:47 Common Mental Blockers in Personal Growth14:01 The Impact of Thoughts on Reality16:43 The Role of Genetics in Happiness19:21 The Pursuit of Happiness and Satisfaction22:29 Overthinking and Its Effects28:43 Overcoming Overthinking: The Power of Presence32:35 Embracing the Present: Letting Go of Future Worries34:26 Facing Discomfort: The Human Experience37:10 Taking Ownership: The Role of Personal Responsibility40:42 Worrying About Others' Opinions: A Common Struggle45:03 The Illusion of Perception: How We View Ourselves51:47 Authenticity vs. Performative Vulnerability: Finding Balance54:53 Mindset Training: Unlocking Your Potential
This episode covers Klinefelter syndrome.Written notes can be found at https://zerotofinals.com/paediatrics/genetics/klinefelter/Questions can be found at https://members.zerotofinals.com/Books can be found at https://zerotofinals.com/books/The audio in the episode was expertly edited by Harry Watchman.
In this episode of the Flex Diet Podcast, I sit down with Dr. Lauren Colenso-Semple to cut through the noise and tackle some of the most persistent myths in women's fitness. We break down where misinformation shows up in popular programs, why overly complicated plans often backfire, and what the science actually says about fasted training and low energy availability. We also get into hot topics like cold water immersion and cortisol, real sex-based differences in training responses, and why women's fitness research is still so challenging to conduct well. If you're looking for practical, evidence-based guidance instead of hype, this episode will help you train smarter and with more confidence.Sponsors:LMNT: http://drinklmnt.com/mikenelson (automatically applied at checkout)Beyond Power Voltra 1: https://www.beyond-power.com/michael13Fitness Insider Newsletter: https://miketnelson.com/Episode Chapters:04:30 Interview with Dr. Lauren Colenso-Semple05:01 Complications in Women's Fitness07:39 Effective Training Strategies18:42 Fasted Training for Women23:33 Low Energy Availability28:50 Cold Water Immersion for Women34:27 The Overemphasis on Recovery36:45 Sex-Based Differences in Training37:04 The Fiber Type Debate43:41 Genetics and Athletic Performance46:23 Women's Specific Supplements53:50 Challenges in Women's Fitness Research01:00:51 Rapid Fire Questions and ConclusionEpisodes You Might Enjoy:Episode 267: Demystifying Women's Fitness and Nutrition with Alli FahrenbachYouTube: https://youtu.be/w13NXowjSVU?si=QDdKNRGZZq_SgT5hEpisode 296: Enhancing Athletic Performance with Dr. Dani LaMartinaYouTube: https://youtu.be/ts_eqvs6OI4?si=TiqFPjcsxI9a3owFConnect with Dr Lauren Colenso-Semple:Website: https://www.drlaurencs.com/Instagram: https://www.instagram.com/drlaurencs1Get In Touch:Instagram: https://www.instagram.com/drmiketnelson/YouTube: https://www.youtube.com/channel/UCn1aTbQqHglfNrENPm0GTpgEmail: https://miketnelson.com/contact-us/
What's better than covering a sale of clubby females that are as good as any in the industry? Rockin H entrusted us to cover their entire sale, and it's flat awesome. There's so much variation in type and kinds, color, and opportunities. Rockin H has been working hard to build a reliable program, and they have sure done that! There's a special one at the end that we all believe is a pretty special show heifer! Find it on SteerBidder, it all happens on the 29th! Empowerment Is Here. Link
Send us a textEpisode 142 of the Joint Dynamics Podcast JD host Andrew Cox | Joint Dynamics features Mariano García-Valiño. Mariano is a four-time health-tech entrepreneur and CEO of Axenya, a company revolutionizing healthcare with AI, advanced software, data science, and human-centered support. Mariano has led the creation, scaling, and exit of major companies including a $9 billion sale and a $1 billion IPO, with earlier roles at Pfizer, Lilly, McKinsey, and global investment firms. Beyond his business acumen, Mariano supports his drive and innovative mindset via his dedication to meditation and his work as an experimental art photographer, blending creativity and mindfulness to fuel his leadership. He is also the Amazon #1 bestselling author of "INEDIBLE," which explores why healthcare lags in technology adoption and how to fix it. Mariano holds an Engineering degree from Universidad de Buenos Aires and an MBA from Harvard Business School earned on a Fulbright Scholarship, underscoring his diverse expertise in entrepreneurship, technology, and human-centered innovation.Quick recap*Show sponsor is Muvitality Medicinal Mushrooms for modern day health and wellness | Mu …Go to muvitality.com and use the code JD10 to receive a 10% discount on your purchase of Mu Functional mushrooms such as Lions Mane, Cordyceps, Chaga, Reishi, and Turkey tail functional mushroomsEnjoyHere are some useful links for this podcastMariano's Book - Software is eating the world, yet healthcare remains INEDIBLE: How to Build the Modern, Tech-Enabled, Healthcare Experience - https://www.amazon.com/Software-eating-healthcare-remains-INEDIBLE-ebook/dp/B0FVGLQ1QF?ref_=ast_author_dp&th=1&psc=1www.mgarciavalino.comRelevant episodesEpisode 122 - Dr Christine Houghton on Genetics, Nutritional Biochemistry & Sulforaphane https://podcasts.apple.com/hk/podcast/episode-122-dr-christine-houghton-on-genetics-nutritional/id1527374894?i=1000699475907JOINT DYNAMICS links:Joint Dynamics Facebook - https://www.facebook.com/JointDynamicsHongKong/Joint Dynamics Instagram -https://www.instagram.com/jointdynamics/Joint Dynamics Youtube - https://www.youtube.com/channel/UCRQZplKxZMSvtc6LxM5WckwJoint Dynamics Website - www.jointdynamics.com.hk Host - Andrew Cox - https://www.jointdynamics.com.hk/the-team/trainers/andrew-cox
Discover the hidden factors behind hair loss—from genetics and hormones to stress, medications, and nutrition. Our guest unpacks the science, shares real stories, and reveals why understanding the root cause is everything. Your hair health questions, answered. WhatCausesHairloss.net City: Philadelphia Address: 4571 Argonne Street Website: https://whatcauseshairloss.net
Guests:Kate Adamala, Associate Professor of Genetics, Cell Biology, and Development at the University of MinnesotaGlyn Tallon, Founder of Tallon Mortuary Specialists in Navan
Nspecta of CSI Humboldt and Bodhi join Matthew Riot of Riot Seeds to Present, Review and Discuss "The Cannabible" by Jason King, Book 2 (the red one). Part 2. Educational, historical, & public interest used with permission by the author.
We dig into why visceral fat drives disease risk, how to spot it on sight and imaging, and the levers that shrink it without losing muscle. We map a practical plan across food, fasting, light, stress, and training, and weigh GLP-1s and surgery against lifestyle-first care.Christopher J. Stadtherr, MD is a board-certified physician in Family Medicine and Obesity Medicine, with expertise in nutrition and metabolic health. He practices metabolic medicine in a direct primary care (DPC) model out of Gig Harbour, WA, USA and is committed to helping his patients reverse their diabetes, improve their metabolic health, and avoid the myriad complications that necessitate hospitalization.CONSULT DR MAXInitial consult - https://www.drmaxgulhane.com/offers/5jfDvLyH/checkoutSUPPORT MY WORK
* Dino Dave: This week Fred Williams and Doug McBurney welcome Dave Woetzel of Dino Dave fame on YouTube, at Genesis Park, in churches, globally (and beyond)! *Tune in to YouTube for the FULL Video: The full video (parts 1 and 2) will be released soon on the RSR YouTube Channel. * Origins, Giants and the Bible: Hear how stories of giants in the Bible, (along with extra biblical legends) and the fossil record of giant organisms confirm Biblical creation. * Antediluvian Giants: Who were the "sons of God" who took the daughters of men as wives in Genesis 6:2? Who were the "mighty men" and "men of renown in verse 4?" Were the pre-flood giants the offspring of fallen angels or men? Hear about the three common views: the Regal, Sethite and Fallen Angel theories of just who these giants were. * Post Flood Giants: How and why did the giants of the pre-flood world seem to reappear in the Promised Land while Israel was in Egypt and afterward, all the way up to the time of King David. * Goliath: Hear about the difference between a biblical giant like Goliath and modern "giants" like Robert Wadlow who suffered from gigantism, (along with archaeological confirmation of ancient weapons like those described in the Bible)! * American Giants? Hear Dave begin to discuss how he got interested in Giants from reading a book called The Ancient Giants who Ruled America on a trip to the mound-builder capital of St Louis.
This episode covers Down syndrome.Written notes can be found at https://zerotofinals.com/paediatrics/genetics/downs/Questions can be found at https://members.zerotofinals.com/Books can be found at https://zerotofinals.com/books/The audio in the episode was expertly edited by Harry Watchman.
Send us a textOn today's episode of The Myopia Podcast:How he got started in optometry. The reason behind his passion in Myopia Management. What it's like to be a high myope.How genetics affect myopia in children. What are some ways to encourage children to spend time outdoors. I hope you learned a lot from this episode.About Dr. Tim Earley:Dr. Timothy Earley obtained his B.S. in Biology from the University of Scranton in 1994.He then obtained both a B.S. in Visual Science and a Doctorate in Optometry from thePennsylvania College of Optometry in 1998. After graduation, he joined the MedinaVision and Laser Centre, where he served as a therapeutic optometrist until December2020 when he joined Northeast Ohio Eye Surgeons. He spent 23 years as the vicepresident/secretary of Medina Vision Centre and was the director of human resources.Dr. Earley has a special interest in the diagnosis and management of age-relatedmacular degeneration (AMD), dry eye and ocular surface disease, co-management ofcataract and refractive surgery, and the fitting of multifocal and specialty contact lenses.Reflecting his commitment to public health, Dr. Earley is the Clinic Director of the BrightEyedeas Vision Clinic. At Bright Eyedeas, high school students enrolled in the opticaltechnology/visual sciences program work with Dr. Earley to provide no-cost eyeexaminations and eyeglasses for patients in need. He also participates in InfantSEE, apublic health program designed to ensure that vision care becomes an essential part ofinfant wellness.Dr. Earley is a member of the American Optometric Association and the OhioOptometric Association. He is also a national speaker and consultant in the areas ofspecialty contact lenses, macular degeneration, and practice management. He is aconsultant for Alcon and a member of the Practitioner's Visiting Alcon (PVA) faculty. Dr.Earley serves as a KOL for Notal Vision, and is currently on the Speaker Bureau and isa KOL for Maculogix and MacuHealth. Dr. Earley has been published in OptometricManagement, Advanced Ocular Care, and Review of Optometry, and is a COPEapproved continuing education lecturer. He currently contributes a Business Strategiescolumn for Optometric Management and serves on its editorial advisory board.When not seeing patients or consulting with industry partners, Dr. Earley enjoysspending time with his wife, Dr. Andrea Earley, and his three children. He enjoys theoutdoors, hiking, golfing, and gardening. He has a small flock of chickens and hopes toexpand his hobby farm in the future.---If you're considering or have ever considered getting a virtual team member for your practice check out hiredteem.com, mention The Myopia Podcast when signing up for a $250 dollar discount off of your first month's teem member.https://hireteem.com/myopia-podcast/
We are currently living in an epidemic of a sedentary lifestyle. As we live through our screens whether it be glued to our phones, tablets, or laptops, we tend to miss out on the benefits of movement in our day to day lives - how does movement benefit us?In this episode, Dr. Krista Kostroman, Chief Science Officer of the DNA Company, is joined by Dr. Emily Splichal. She is a functional podiatrist and human movement specialist, is the mind behind Naboso. With a spirit to challenge conformity, Dr. Splichal has taken her conventional Podiatric Medical degree and combined it with years of experience and expertise in human movement and sensory science to found Naboso.Dr. Splichal believes that our experience in this world is built around sensory stimulation and our ability to process, perceive, and integrate this information effectively. Since 2012, Dr. Splichal has been traveling the world to share her unique approach to human movement, foot function, and barefoot science. Having taught in 35 countries and to over 25,000 professionals, Dr. Splichal has quickly become a sought out leader in barefoot training and rehabilitation. Here are the highlights of today's episode:03:59 How Our Body Feeds Into Mental Experiences08:59 How People Can Shift Through Movement and Fascial Engagement15:17 Walking as An Access Point to Health26:04 How Fascia and Movement Informs Our Genetic Expression40:16 Supporting Fascia and Microvasculature46:33 Reintegrating Body with Space51:43 ConclusionIf you wish to learn more from Dr. Emily Splichal and Naboso, you may do so through the following channels:Website: https://www.naboso.com/Instagram: https://www.instagram.com/naboso_technology/YouTube: Master Movement with Naboso______________________________________________________Keep yourself up to date on The DNA Talks Podcast! Follow our socials below:The DNA Talks Podcast Instagram: @dnatalkspodcastThe DNA Company Instagram: @thednacoThe DNA Company's Official Tiktok Account: @thednaco3______________________________________________________Medical Disclaimer: The information provided in this communication is for general informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read here. If you think you may have a medical emergency, call your doctor or 911 immediately.
Today we are featuring two articles that relate to moving genetics into mainstream healthcare. In our first segment, we discuss polygenic risk scores and the transition from research to clinical use. Our second segment focuses on hypermobility Ehlers Danlos Syndrome and the triaging of clinical referrals. Segment 1: Readiness and leadership for the implementation of polygenic risk scores: Genetic healthcare providers' perspectives in the hereditary cancer context Dr Rebecca Purvis is a post-doctoral researcher, genetic counsellor, and university lecturer and coordinator at The Peter MacCallum Cancer Centre and The University of Melbourne, Melbourne, Australia. Dr Purvis focuses on health services delivery, using implementation science to design and evaluate interventions in clinical genomics, risk assessment, and cancer prevention. In this segment we discuss: - Why leadership and organizational readiness are critical to successful clinical implementation of polygenic risk scores (PRS). - How genetic counselors' communication skills position them as key leaders as PRS moves from research into practice. - Readiness factors healthcare systems should assess, including culture, resources, and implementation infrastructure. - Equity, standardization, and implementation science as essential tools for responsible and sustainable PRS adoption. Segment 2: A qualitative investigation of Ehlers-Danlos syndrome genetics triage Kaycee Carbone is a genetic counselor at Boston Children's Hospital in the Division of Genetics and Genomics as well as the Vascular Anomalies Center. Her clinical interests include connective tissue disorders, overgrowth conditions, and somatic and germline vascular anomaly conditions. She completed my M.S. in Genetic Counseling at the MGH Institute of Health Professions in 2023. The work she discusses here, "A qualitative investigation of Ehlers-Danlos syndrome genetics triage," was completed as part of a requirement for this graduate program. In this segment we discuss: - Why genetics clinics vary widely in how they triage referrals for hypermobile Ehlers-Danlos syndrome (hEDS). - How rising awareness of hEDS has increased referral volume without clear guidelines for diagnosis and care. - The ethical and emotional challenges genetic counselors face when declining hEDS referrals. - The need for national guidelines and clearer care pathways to improve access and coordination for EDS patients. Would you like to nominate a JoGC article to be featured in the show? If so, please fill out this nomination submission form here. Multiple entries are encouraged including articles where you, your colleagues, or your friends are authors. Stay tuned for the next new episode of DNA Dialogues! In the meantime, listen to all our episodes Apple Podcasts, Spotify, streaming on the website, or any other podcast player by searching, “DNA Dialogues”. For more information about this episode visit dnadialogues.podbean.com, where you can also stream all episodes of the show. Check out the Journal of Genetic Counseling here for articles featured in this episode and others. Any questions, episode ideas, guest pitches, or comments can be sent into DNADialoguesPodcast@gmail.com. DNA Dialogues' team includes Jehannine Austin, Naomi Wagner, Khalida Liaquat, Kate Wilson and DNA Today's Kira Dineen. Our logo was designed by Ashlyn Enokian. Our current intern is Stephanie Schofield.
Send us a textHow seasonal changes in light and dietary unsaturated fats affect circadian rhythms in mammals.Topics Discussed:Evolutionary context of circadian rhythms: All organisms have adapted to Earth's 24-hour day for survival, with internal clocks slightly offset and adjusted by environmental cues.Molecular clock mechanism: Involves a feedback loop where proteins turn on/off genes, lasting ~24 hours, regulated by phosphorylation and degradation for timing precision.Genetic variations in sleep: Families with mutations in clock genes like PER2 cause extreme morning lark behavior, altering protein stability and period length by hours.Light entrainment: Morning light shortens human clocks (average 24.2 hours) to match 24-hour days; seasonal day length changes require gradual adjustments.Food & metabolic links: Seasonal food scarcity/abundance affects clock via glucose and fatty acids competing for protein modifications, as shown in diabetic mouse models.Role of unsaturated fats: Paper finds MUFA/PUFA ratios in diet alter phosphorylation of clock proteins, speeding or slowing adaptation to winter/summer light cycles in mice.Modern environmental impacts: Artificial light extends “daytime” signals, while constant food access erases seasonal patterns, contributing to obesity and diabetes risks.Jet lag & adaptations: Sudden time shifts mimic seasonal experiments; high-sugar/fat intake may phenocopy genetic effects to aid adjustment, though not recommended for health.Practical Takeaways:Expose yourself to morning natural light to help synchronize your internal clock and improve daily energy.Consume main meals during daylight hours and avoid late-night eating to align with natural metabolic rhythms.Limit evening screen time to reduce artificial blue light disrupting sleep onset.Consider varying diet seasonally, favoring diverse, whole foods to mimic natural availability patterns for better health.About the guest: Louis Ptacek, MD is a neurologist and professor at the University of California, San Francisco. He researches inherited neurological diseases and sleep traits, including genetic variations causing extreme early rising.Related Episode:M&M 237: Circadian Biology: Genetics, Behavior, Metabolism, Light, Oxygen & Melatonin | Joseph Takahashi*Not medical advice.Support the showAffiliates: Lumen device to optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off. AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models. Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) For all the ways you can support my efforts
Have a message for Karena? She'd love to hear from you and share your comment or question on air!Leave Karena a voicemail: https://www.speakpipe.com/KarenaDawnWhat if the sign you needed appeared at your darkest moment—and changed everything?In this deeply moving episode of The Big Silence, Karena sits down with actress, producer, and mental health advocate Sarah Gilman. Best known for her starring role as Delia Delfano in Disney Channel's "I Didn't Do It," Sarah has built an impressive career in Hollywood. But behind the bright lights lies a powerful story of survival. From her first suicidal thoughts at age eight, Sarah's journey is one of raw honesty and radical hope. Now, as the founder of the DD Hirsch NextGen Advisory Council, she's dedicated her life to mental health advocacy, making sure no one feels alone. Whether you're struggling yourself, supporting someone you love, or working to understand mental health better, Sarah's courage will inspire you to keep going.How do you rebuild your sense of self after hitting rock bottom, and learn that asking for help isn't a weakness?Stripping away shame and finding community proves that healing isn't linear. It's about showing up for yourself, even when it's hard.(01:37) When the Darkness StartedSarah's first journal entries about suicide as a young childCoping mechanisms that became self-destructiveThe suicide attempt that made her realize she wanted to liveThat split-second moment of regret—and why survivors often feel the same way(05:34) The Roots of Mental Illness: Family, Genetics & EnvironmentGrowing up with threads of OCD, anxiety, and depression in Sarah's familyThe collision of genetics and lack of emotional educationShared experiences as suicide survivors(08:03) Rock Bottom, Therapy & The Fork in the RoadWhen friendships dissolved Her moment of reckoning: keep going and die, or ask tough questions and healDeep diving into psychology, sociology, philosophy, and neuroscienceLearning she's a "big feeler" who just needed healthier ways to express emotions(18:45) Finding Your People: Community, Connection & HealingHow sharing experiences becomes part of the healing processThe power of being seen in your struggleWhy normalizing mental health conversations changes everything(27:30) Breaking the Stigma: Advocacy, Education & Social MediaUsing personal stories to create change in mental health spacesHow younger generations are reshaping mental health conversationsNavigating social media as both a tool and a potential trigger(38:15) Body Image, Eating Disorders & What Really MattersSarah's experience with eating disorders and recoveryWhy she doesn't post body pictures on social media anymoreThe realization: "My body is the least interesting thing about me"(50:19) Live from Vegas: The Not Alone Summit & 98816.5 million people have used 988 since 2022How 988 works: call or text for immediate, anonymous supportDebunking myths: less than 1% of cases escalate to 911, over 90% are de-escalatedSpecialized support available for LGBTQIA+, veterans, and different languagesReconnect with yourself and your community: We start the New Year, New TI-YOU Challenge January 5th in the Tone It Up App....
In this episode of The Healthspan Podcast, Dr. Robert Todd Hurst, MD, FACC, FASE, sits down with Natasha Mortenson, a HealthspanMD member, for a real-world transformation story that challenges what most people believe about aging, muscle, and hidden risk. Natasha shares how a DEXA scan revealed opportunities she could not see on the surface, and how small, deliberate changes over time led to dramatic body composition improvements, including losing 12 pounds of fat while gaining two and a half pounds of muscle in eight months. They also dig into what Natasha calls the iceberg syndrome, the hidden risk beneath “looking healthy,” the role of testing and re-testing, and why “one size fits all” advice breaks down in real biology. About the Guest: Natasha Mortenson is a HealthspanMD member sharing her personal longevity and body composition journey, including how objective testing, personalized planning, and consistent strength-focused work helped her pursue exceptional results and reduce future health risks.
In this episode of the Let's Talk Thyroid podcast, I am speaking with Dr. Sam Shay, a functional medicine expert, discussing the complexities of thyroid health. We explore the importance of comprehensive thyroid testing - not just the thyroid panel but other tests that can help unpack solutions to managing thyroid health. Dr Shay identifies 6 often overlooked categories of tests to explore:Nutritional deficienciesMitochondriaGut HealthGeneticsHormonesAdrenalHere is some of what we talk about and where to find it00:00 Introduction to Functional Medicine and Thyroid Health05:29 Understanding Thyroid Testing and Nutritional Deficiencies11:00 The Role of Mitochondria in Thyroid Function17:01 Gut Health and Its Impact on Thyroid22:40 Genetics and Thyroid Health28:10 The Influence of Hormones and Stress on Thyroid Function33:42 Holistic Approaches to Thyroid ManagementDr. Sam Shay, DC, IFMCP is a functional medicine expert, speaker, and stand-up comic who helps people get out of survival mode and reclaim their energy, focus, and vitality through personalizedfunctional lab testing and his signature NeuroHarmony Model™After overcoming years of chronic fatigue, insomnia,and digestive issues since childhood, Dr. Sam turned his recovery into a mission. He's spent the last 25 years mastering the science of nutrition, mind-body medicine, and clinical lab testing to decode the root causes of burnout, overwhelm, and chronic health issues.Known as the “friendly lab nerd,” Dr. Sam makes advanced lab testing approachable—combining deep data analysis with relatable insights to help clients balance hormones, heal the gut, optimizesleep, and reduce inflammation. His unique NeuroHarmony Model™ weaves together functionaltesting with nervous system regulation to create sustainable health—not just short-term symptomfixes.He's been featured on over 200 podcasts and summits and brings an engaging, humorous tone to even the most complex health topics. Dr. Sam empowers his audience with practical tools to feelbetter and function at their best.Connect with Dr Shay:YouTube: https://www.youtube.com/tenpointwellness/Facebook: https://www.facebook.com/sam.shay.792/Instagram: https://www.instagram.com/drsamshay/Head to drsamshay.com/DNA-decoded and enter code GOLD100 for $100 off the Gold programLet's Talk Thyroid is a podcast where we explore different aspects of living thyroid-friendly lifestyle positively & practically to help you thrive and not just survive.⭐️ WEBSITE: https://letstalkthyroid.com
Overview This special episode of the [Tick Boot Camp Podcast](https://tickbootcamp.com/podcast/) was recorded live at the 2nd Annual Alzheimer's Pathobiome Initiative (AlzPI) and PCOM Symposium in collaboration with Pathobiome Perspectives. Hosted by Ali Moresco in partnership with Nikki Schultek, Executive Director of AlzPI, the conversation continues the Tick Boot Camp mission of exploring infection-associated chronic illness (IACI)—including Lyme disease and other tick-borne infections—within the global Alzheimer's and neuroimmunology research community. Tick Boot Camp co-founders Matt Sabatello and Rich Johannesen partnered with Ali and Nikki to highlight leading scientists connecting microbes, immune dysregulation, and neurodegenerative disease. This episode features Dr. Elizabeth “Betsy” Bradshaw, Assistant Professor of Neurology at Columbia University Irving Medical Center, whose research investigates how past infections leave lasting imprints on the brain's immune system and influence the development of Alzheimer's disease. Guest Elizabeth M. Bradshaw, PhD Assistant Professor of Neurology, Columbia University Irving Medical Center Principal Investigator, Bradshaw Laboratory – Neuroimmunology and Genetics of Alzheimer's Dr. Bradshaw's laboratory focuses on the immune system's role in neurodegeneration, particularly how infection and inflammation alter brain immunity and predispose individuals to conditions like Alzheimer's disease. Her work builds on large-scale genome-wide association studies (GWAS) that identified immune-related genetic variants linked to Alzheimer's susceptibility, suggesting that subtle changes in immune function—not just neuronal factors—may underlie disease onset. Her team is exploring how pathogens such as HSV-1 (Herpes Simplex Virus Type 1) interact with the brain's immune cells, known as microglia, and how these infections can “reprogram” immune responses long after the pathogen is cleared. Key Discussion Points Dr. Bradshaw explains how her research bridges genetics, immunology, and infectious disease to better understand Alzheimer's. Through GWAS data, her team found that many of the genes linked to Alzheimer's risk involve immune pathways rather than neuronal signaling. This discovery redirected the field's attention toward how immune cells respond to pathogens and environmental stressors across a lifetime. Using human-derived microglia-like cells created from blood monocytes, her team observes how infections reshape immune cell metabolism and memory. By infecting these microglia-like cells with Alzheimer's-associated pathogens like HSV-1, they study how genetic background and infection history determine immune cell behavior. The findings suggest that past infections may epigenetically and metabolically train microglia—changing how they respond to aging, stress, and amyloid buildup. Even when the infection has resolved, these “reprogrammed” immune cells can remain altered for decades, silently increasing the brain's vulnerability to neurodegeneration. Dr. Bradshaw emphasizes that understanding how infections rewire the brain's immune landscape could transform early intervention strategies. Identifying combinations of genetic risk factors and pathogen exposures may enable targeted prevention or immune-modulating treatments long before symptoms appear. “Microglia remember. Even after the pathogen is gone, they carry its imprint—responding differently decades later when the brain faces new challenges.” — Dr. Elizabeth Bradshaw Why It Matters Dr. Bradshaw's work reframes Alzheimer's disease as a neuroimmune condition shaped by infection and host genetics. Her research highlights how microbial exposures, immune history, and inflammation converge to influence cognitive decline. By integrating infection biology with genetics and immunology, her team is redefining how scientists and clinicians view the root causes of Alzheimer's and other neurodegenerative diseases. This work strengthens the growing case that the immune system's “memory” of infection may be one of the most important and overlooked factors in brain health and aging. About the Event This interview was recorded at the 2nd Annual Alzheimer's Pathobiome Initiative (AlzPI) and Philadelphia College of Osteopathic Medicine (PCOM) Symposium, held October 3, 2025, at Ohio University in Dublin, Ohio. The event brought together more than 20 leading researchers exploring how microbes, the microbiome, and immune dysregulation contribute to Alzheimer's, dementia, and infection-associated chronic illness (IACI). Tick Boot Camp partnered with Ali Moresco and Nikki Schultek to share these conversations and connect chronic Lyme, infection, and neurodegenerative research communities. Learn More Learn more about the Alzheimer's Pathobiome Initiative (AlzPI) Listen to Tick Boot Camp Podcast episodes, including Episode 406: Pathobiome – An Interview with Nikki Schultek and Episode 101: The Young Gun – An Interview with Alex (Ali) Moresco discussed in this interview.
Dr. David Agus, USC Professor of Medicine and CEO of the Ellison Institute for Transformative Medicine, treats presidents, CEOs and cultural icons and has spent decades studying one question: What determines how long and well we live?His answer is hopeful: Only 4% is genetic. The other 96% is under your control.In this episode, he reveals why elephants rarely get cancer, why giraffes never get heart disease, and what inflammation does to nearly every organ in your body. He also shares the simple, proven habits that matter more than DNA, and destroys the myths quietly harming millions.Science-backed. Actionable. Hopeful.
Guest: Dr. Jayne Danska is a Senior Scientist, Genetics and Genome Biology at the Hospital for Sick Children Research Institute. She is also Associate Chief of Research, Faculty Development and Diversity, and Professor at the University of Toronto. Her research focuses on the microbiome in type 1 diabetes. She discusses insights from longitudinal human studies and mouse models. (40:00) Featured Products and Resources: Register now for IMMUNOLOGY2026! Wallchart: T Cell Nomenclature: From Subsets to Modules The Immunology Round Up Vaccination for Anaphylaxis – A vaccine against IgE protected against anaphylaxis in a mouse model. (2:53) How RSV Can Lead to Asthma – Researchers identified maternal allergy and neonatal RSV infection as converging Fc receptor-dependent risk factors for asthma. (9:50) Antigen Presentation for MAIT Cell Immunity – Macrophages are key for MR1 antigen presentation and MAIT cell immunity. (20:30) HIV Remission after Stem Cell Transplantation – After an allogeneic stem cell transplant, a patient discontinued antiretroviral therapy and sustained HIV remission for over six years. (27:00) Subscribe to our newsletter! Never miss updates about new episodes. Subscribe
This epsiode is brought ot you by LMNT, Strong Coffee Company, Legion Athletics and Fatty15. After healing from Hodgkin's lymphoma in her 30s, Elissa Goodman turned her personal health crisis into a lifelong mission: helping others prevent and recover from cancer through holistic nutrition and mindful living. In this episode, she opens up about her journey from stress-driven corporate life to deep healing through green juicing, plant-based eating, and inner work like yoga, trauma release, and plant medicine. Elissa discusses how trauma, inflammation, and our toxic environment create the "cancer terrain"—and how we can reverse it with simple, nutrient-dense habits and radical self-love. Her story is not just about healing cancer but transforming one's entire way of living. Follow Elissa @elissagoodman Follow Chase @chase_chewning ----- 00:00 – The Current Cancer Epidemic 03:00 – Diagnosis at 32 & Discovering Juicing 07:00 – Taking Healing into Her Own Hands 11:00 – The Power of One Question: "Are You Happy?" 15:00 – Losing Her Husband & What Holistic Healing Taught Her 21:00 – Top Anti-Cancer Foods & The Inflammation Connection 28:00 - Cacao, Grief, and Plant Medicine as Emotional Healing Tools 33:00 - The Cancer Terrain: Internal Environment vs. Genetics 38:00 - Detoxification Basics: Sweat, Sleep, & Simplicity 43:00 - Myths About Juicing, Water Fasting, and Sugar ----- Episode resources: Get a FREE electrolyte variety mix with any purchase at https://www.DrinkLMNT.com/everforward Save 15% on organic coffee and lattes wiht code CHASE at https://www.StrongCoffeeCompany.com Get an additional 15% off the 90-day starter kit of C15:0 essential fatty acids at https://www.Fatty15.com/everforward Get 20% off your entire first purhcase with code EVERFORWARD at https://www.LegionAthletics.com Watch and subscribe on YouTube
This episode covers genetic testing.Written notes can be found at https://zerotofinals.com/paediatrics/genetics/testing/Questions can be found at https://members.zerotofinals.com/Books can be found at https://zerotofinals.com/books/The audio in the episode was expertly edited by Harry Watchman.
Many people using donor conception or surrogacy feel “different” and quietly wonder what family really means when genetics aren't shared in the way they expected. In this episode, I talk about chosen family in the context of donor conception and surrogacy: how to see yourself not as “other,” but as part of a growing, very real type of family. We'll explore: • How the concept of family has changed – and where you fit in • Why grief about not using your or your partner's genetics is natural • How grief about genetics and your bond with your child often get conflated (and why they're different) • How to think about who is in your “inner circle” • How to decide what to share with close family and friends, and what to keep private • Why doing both the inner work (your own feelings) and the external work (how you talk to others) can help you feel more prepared for the future If you're building your family with donor sperm, donor eggs, embryos, or surrogacy, you are not alone – and you are not less of a family. There are ways to navigate grief, boundaries, and conversations that honor you, your partner, and your child.
In this conversation, we connect with Bob Gilpatrick to explore the science of longevity, epigenetic reprogramming, holistic wellness, and the future of anti-aging breakthroughs. Bob is the President and Co-Founder of Boomers Forever Young, an anti-aging and nutrition company, and brings more than 20 years of experience as a Holistic Health Therapist. He is also a Certified Holistic Nutritionist, a Heart-Centered Therapist, and a trusted guide for individuals seeking advanced nutritional strategies. Bob is widely known for his ability to explain complex aspects of aging in simple, accessible language — shedding light on topics rarely discussed in mainstream health conversations. He also provides insight into revolutionary nutritional technologies designed to support deeper healing and improved longevity. Throughout his career, Bob has trained with many of the world's leading holistic health pioneers. His work focuses on nutritional consulting, with a special emphasis on supporting individuals with diabetes, weight-loss goals, and intestinal disorders. Listen in to find out: What epigenetics are, and what it means to reprogram them. The role that gaining muscle plays in overall health and longevity. How to leverage various "de-aging" mechanisms. The new anti-aging technologies that are shaping the future of personal health. Keep up with Bob and his work on LinkedIn!
Thank you for watching!https://breeders-syndicate-shop.fourthwall.com/promo/SYNDICATE15~ALL BREEDERS SYNDICATE LINKS: https://linktr.ee/riotseeds~SYNDICATE GEAR (shirts, stickers, beanies etc):https://breeders-syndicate-shop.fourthwall.comSUPPORT the channel or JOIN the Discord community:https://www.buymeacoffee.com/matthewriot
The eagle has landed! The king of the Wooks Miles @fermentedplantextracts and I have driven the ADS Mobile Studio through the tumbleweeds to the @cowboycupofficial in Tulsa Oklahoma. the booth is built and we are on site! We will have Genetics from both of us including seeds from our Mesa Cookies colab that are paired with some @sagemasta_select unreleased Alien Rock candy hybrids. We will also be joined by Terry from @operationgreenhealing and his “service” dog Gracie at the booth you'll have to stand in line to talk to her. Coming through we also have ADS Superfan @uncut_bush. We will talk to the organizers,vendors and some past and possible current winners. Of course the man on the scene James bean is here in with the @seedsherenow_seed_bank . We are also glad to announce that we have upgraded the mobile studio with starlink so this should be a flawless show…. Uh oh did I just jinx it, you'll have to watch to find out. So get that @dabx GO rig charged your @jerome_baker bong Clean with some ice
* Dino Dave: This week Fred Williams and Doug McBurney welcome Dave Woetzel of Dino Dave fame on YouTube, at Genesis Park, in churches, globally (and beyond)! *Tune in to YouTube for the FULL Video: The full video (parts 1 and 2) will be released next Wednesday, Dec 17 of the RSR YouYube Channel. * Origins, Giants and the Bible: Hear how stories of giants in the Bible, (along with extra biblical legends) and the fossil record of giant organisms confirm Biblical creation. * Antediluvian Giants: Who were the "sons of God" who took the daughters of men as wives in Genesis 6:2? Who were the "mighty men" and "men of renown in verse 4?" Were the pre-flood giants the offspring of fallen angels or men? Hear about the three common views: the Regal, Sethite and Fallen Angel theories of just who these giants were. * Post Flood Giants: How and why did the giants of the pre-flood world seem to reappear in the Promised Land while Israel was in Egypt and afterward, all the way up to the time of King David. * Goliath: Hear about the difference between a biblical giant like Goliath and modern "giants" like Robert Wadlow who suffered from gigantism, (along with archaeological confirmation of ancient weapons like those described in the Bible)! * American Giants? Hear Dave begin to discuss how he got interested in Giants from reading a book called The Ancient Giants who Ruled America on a trip to the mound-builder capital of St Louis.
This episode covers mitochondrial inheritance.Written notes can be found at https://zerotofinals.com/paediatrics/genetics/mitochondrialinheritance/Questions can be found at https://members.zerotofinals.com/Books can be found at https://zerotofinals.com/books/The audio in the episode was expertly edited by Harry Watchman.
What if everything you thought was broken in your body could be rebuilt?That is the lens through which strength coach and health educator Tom Nikkola lives his entire life. In this episode of Love at First Science, Tom shares the story that shaped his philosophy: being diagnosed with childhood leukemia, undergoing years of invasive treatment and still walking away with optimism, curiosity and a fascination for how the body heals. Tom explains how his early experiences fuelled a lifetime pursuit of understanding the human body, from pre-med studies to corporate roles in nutrition and metabolic testing, and eventually to his coaching platform Vigor Training. We explore the core principle that underpins his work: when you give the body the conditions it needs, it has an astonishing ability to repair, adapt and strengthen.This conversation moves from Tom's personal story into practical science, including:Why a flexible nervous system is one of the most powerful markers of resilienceHow weight training helps you shift between sympathetic and parasympathetic statesThe fundamentals of the MTHFR gene, methylation and why so many people feel unwell without knowing whyWhy diet, stress management and sleep matter more than most people realiseTom breaks down what MTHFR actually is, how it affects detoxification, mood and energy, and which nutritional and lifestyle strategies truly help. He explains why methylated B vitamins are essential for many people, where folate appears in food, and why leafy greens and high protein diets remain foundational. He also shares why overtraining, poor sleep and high stress often exacerbate symptoms. Whether you are navigating your own health challenges, supporting clients or simply curious about how physiology shapes wellbeing, Part One offers grounded, compassionate science with immediately usable insights.Stay tuned for Part Two where we continue the discussion and go deeper into hormones, metabolism, testing, detoxification and Tom's signature philosophy for long term health.About TomTom Nikkola is a seasoned strength and conditioning coach and nutrition strategist with over 23 years of experience in the fitness industry. After serving as Senior Director of Nutrition and Weight Management at a major fitness company, he left the corporate world to build something of his own.Tom's mission is to cut through health noise and bring sustainable, no-nonsense fitness and wellness solutions to people with busy lives. He emphasises strength training, good nutrition, recovery and realistic habits - helping clients build strength, resilience, clarity and vitality for the long haulAbout Alba Yoga AcademyLearn more with Alba Yoga AcademyLearn more about our Yoga Teacher Training here.Watch our extensive library of YouTube videos.Follow Hannah on Instagram.Follow Celest on Instagram
The bible is clear that man cannot choose free of influence or sovereignly determine his outcomes, but did you know that science says the same thing? Today we will look at many things from different scientific perspectives to see what they have to say about the notion of free will.* 00:00 - Introduction * 08:21 - Automatic Processes & Body Facts * 13:11 - Psychology & Neuroscience * 1:15:41 - Genetics* 1:30:48 - Summary Review* 1:34:03 - The Illusion of the 1st Person Perspective* 1:52:40 - The Nature of Information This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.danceoflife.com/subscribe
As we know there is an elevated interest in wild turkey science within the turkey hunting community, we are working to bring you numerous updates and research summaries from the 13th National Wild Turkey Symposium in Kansas City, Missouri. This episode includes conversations with authors or presenters from papers included in the "Wild Turkey Genetics" session: "Role of kinship in sociality of female eastern wild turkeys" — Chamberlain et al. (https://wildlife.onlinelibrary.wiley.com/doi/10.1002/wsb.1630) "Genetic structuring and within-flock relatedness of eastern wild turkeys" — Watkins et al. (Presented by Chamberlain) (https://wildlife.onlinelibrary.wiley.com/doi/10.1002/wsb.1622) Additional guests include the NWTF's Ricky Lackey. While we were not able to sit down and have further conversations about the following paper that also was included in the session about wild turkey genetics, please check out the following research paper titled "Investigating the role of management decisions in subspecies hybridization across the wild turkey's range" — Beckman et al. (https://wildlife.onlinelibrary.wiley.com/doi/10.1002/wsb.1625) To view the full symposium agenda, visit www.wildturkeysymposium.org.
In this deeply vulnerable solo episode, Darin dismantles one of the great myths of modern self-help: that transformation is something you're meant to "do alone." Drawing from neuroscience, anthropology, physiology, and personal experience, he reveals the biological truth — the human nervous system is designed to heal, grow, and stabilize in relationship, not isolation. This conversation explores why loneliness creates physiological damage, why belonging is a survival requirement (not a luxury), and how to intentionally rebuild the village your cells have been waiting for. If you've ever felt like you're doing all the "inner work" but still feel disconnected, this episode is the medicine. What You'll Learn in This Episode 00:00:00 - Opening SuperLife intro narration. 00:00:32 - Sponsor: Therasage — family-driven healing technology, infrared and natural frequency support, details on discount. 00:02:11 - Darin begins the episode — "You were never meant to do this alone." 00:02:22 - The forgotten biology of community and why humans are not built for isolation. 00:03:01 - Your nervous system regulates in relationship — the vagus nerve, safety, co-regulation. 00:03:19 - Social engagement system — coherence, cortisol regulation, belonging as biology. 00:04:03 - Social pain = physical pain; the Baumeister research; the architecture of human connection. 00:05:01 - Tribes, proximity, shared life — Dunbar's number and the limits of real human networks. 00:05:30 - Loneliness as physiology — cortisol elevation, inflammation, disrupted sleep, gray-matter changes. 00:07:01 - Personal growth was never meant to be personal — autonomy, competence, relatedness, love. 00:07:55 - If nobody sees you, your nervous system can't relax — mirrors vs willpower. 00:08:31 - Social contagion of behavior — your network shapes your health. 00:09:01 - Who are you wired into? Environment as epigenetic instruction. 00:10:12 - Why online spaces generate stress instead of transformation. 00:10:35 - Darin's vision: community as a practice, not performance. 00:11:29 - Sponsor: Bite Toothpaste — plastic waste, sustainability, clean ingredients, discount code. 00:13:11 - What if growth wasn't a grind? What if healing was tribal again? 00:13:35 - Building intentional space — not fandom, not following, but practice. 00:14:11 - Supporting the nervous system through community; truth over scrolling. 00:15:04 - Why Patreon — structure, privacy, belonging, circle not feed. 00:15:23 - People looking for truth, depth, real connection — not performance. 00:15:51 - Start building your circle; align with those who align with you. 00:16:12 - You need to be seen, not fixed — community as transformation. 00:17:00 - One person can change your life — the power of being mirrored. 00:17:31 - Men's group, friendships, working out — the daily relational fabric. 00:18:01 - If you're lonely or disconnected, the desire for connection already shifts your biology. 00:18:41 - Darin reflects on a hard year, pain, stem cells, and the deeper healing found in being witnessed. 00:19:26 - Every cell responds when you say yes to deeper connection — the universe moves with it. 00:20:07 - Understanding human biology: we want love, connection, safety, belonging. 00:20:36 - Cutting through "what do you eat" questions — the real priority is connection. 00:21:00 - Closing: "Joy and happiness. Connection. We are built for it… I love you." Thank You to Our Sponsors Therasage: Go to www.therasage.com and use code DARIN at checkout for 15% off Bite Toothpaste: Go to trybite.com/DARIN20 or use code DARIN20 for 20% off your first order. Join the SuperLife Patreon: This is where Darin now shares the deeper work: - weekly voice notes - ingredient trackers - wellness challenges - extended conversations - community accountability - sovereignty practices Join now for only $7.49/month at https://patreon.com/darinolien Find More from Darin Olien: Instagram: @darinolien Podcast: SuperLife Podcast Website: superlife.com Book: Fatal Conveniences Key Takeaway "You don't need to be fixed. You don't need to be saved. You just need to be seen — and we cannot do that alone." Bibliography Neuroscience & Biology of Connection Porges, S. W. (2011). The Polyvagal Theory: Neurophysiological Foundations of Emotions, Attachment, Communication, and Self-Regulation. New York: W.W. Norton. Link to Book Information (Norton) Lieberman, M. D. (2013). Social: Why Our Brains Are Wired to Connect. New York: Crown Publishers. Link to Book Information (Penguin Random House) Eisenberger, N. I. (2012). "The pain of social disconnection: examining the shared neural underpinnings of physical and social pain." Nature Reviews Neuroscience, 13(6), 421–434. Link to Study (PubMed) Thayer, J. F. & Lane, R. D. (2000). "A model of neurovisceral integration in emotion regulation and dysregulation." Journal of Affective Disorders, 61(3), 201–216. Link to Study (ScienceDirect) Psychology of Belonging & Motivation Baumeister, R. F. & Leary, M. R. (1995). "The need to belong: desire for interpersonal attachments as a fundamental human motivation." Psychological Bulletin, 117(3), 497–529. Link to Study (PubMed) Deci, E. L. & Ryan, R. M. (2000). "The 'what' and 'why' of goal pursuits: Human needs and the self-determination of behavior." Psychological Inquiry, 11(4), 227-268. Link to Study (SelfDeterminationTheory.org) Adler, A. (1930s). What Life Could Mean to You. Link to Book Information (Google Books) (Note: Various editions exist) Social Networks & Behavioral Contagion Christakis, N. A. & Fowler, J. H. (2007). "The spread of obesity in a large social network over 32 years." New England Journal of Medicine, 357, 370-379. Link to Study (NEJM) Fowler, J. H. & Christakis, N. A. (2008). "Dynamic spread of happiness in a large social network." BMJ, 337, a2338. Link to Study (BMJ) Centola, D. (2018). How Behavior Spreads: The Science of Complex Contagions. Princeton University Press. Link to Book Information (Princeton University Press) Anthropology & Human Ecology Dunbar, R. I. M. (1992). "Neocortex size as a constraint on group size in primates." Journal of Human Evolution, 22(6), 469-493. Link to Study (ScienceDirect) Henrich, J. (2016). The Secret of Our Success: How Culture Is Driving Human Evolution, Domesticating Our Species, and Making Us Smarter. Princeton University Press. Link to Book Information (Princeton University Press) Loneliness, Inflammation & Health Outcomes Holt-Lunstad, J. et al. (2010). "Social relationships and mortality risk: a meta-analytic review." PLoS Medicine, 7(7), e1000316. Link to Study (PLoS Medicine) Cacioppo, J. T. & Cacioppo, S. (2014). "Social relationships and health: The toxic effects of perceived social isolation." Social and Personality Psychology Compass, 8(2), 58-72. Link to Study (PubMed) Cole, S. W. (2014). "Human social genomics." PLoS Genetics (Cited as PLoS Biology in text, corrected to Genetics based on search), 10(8), e1004601. Link to Study (PLoS Genetics) Group Rituals, Synchrony & Physiology Tarr, B., Launay, J., & Dunbar, R. (2014). "Music and social bonding: 'self-other' merging and neurohormonal effects." Frontiers in Psychology, 5, 1096. Link to Study (Frontiers) Konvalinka, I. et al. (2011). "Synchronized arousal between performers and related spectators in a fire-walking ritual." Proceedings of the National Academy of Sciences, 108(20), 8514–8519. Link to Study (PNAS) Digital Communities & Social Learning Lave, J. & Wenger, E. (1991). Situated Learning: Legitimate Peripheral Participation. Cambridge University Press. Link to Book Information (Cambridge University Press) Wenger, E. (1998). Communities of Practice: Learning, Meaning, and Identity. Cambridge University Press. Link to Book Information (Cambridge University Press)
In this episode of the Gladden Longevity Podcast, Dr. Jeffrey Gladden and Kashif Khan discuss the intersection of genetics, health, and longevity. Kashif shares his personal journey from illness to founding the DNA company, emphasizing the importance of personalized medicine and genetic testing. They explore the unique health challenges faced by women, the impact of trauma and stress on health, and the need for individualized approaches in biohacking. The conversation highlights the significance of understanding hormone metabolism and the role of genetics in parenting, ultimately advocating for a comprehensive analysis of health to achieve optimal outcomes. For Audience · Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/ ! Takeaways · Genetics play a crucial role in understanding individual health. · Personalized medicine is essential for effective treatment. · Women face unique health challenges that are often overlooked. · Understanding hormone metabolism is key to preventing health issues. · Trauma and stress can significantly impact health outcomes. · Biohacking should be individualized, not one-size-fits-all. · Nervous system regulation is vital for overall health. · Genetic predispositions can reveal superpowers and vulnerabilities. · Parenting can be enhanced through understanding children's genetics. · Comprehensive analysis is necessary for accurate health assessments. Chapters 00:00 Introduction to Kashif and His Journey 05:37 The Role of Genetics in Health 08:12 Understanding Individual Health Through Multiple Lenses 11:12 The Importance of Personalized Medicine 14:00 The Intersection of Genetics and Trauma 17:04 Navigating the Biohacking Landscape 19:54 The Impact of Stress and Anxiety on Health 22:59 Transforming Trauma into Superpowers 29:04 The Impact of Social Media on Identity 30:01 Understanding Genetic Potential in Children 32:32 Personalized Parenting Through Genetic Insights 38:39 Women's Health: A Neglected Area 41:25 Hormonal Health and Cancer Risks 47:32 The Precision of Hormonal Treatments To learn more about Kashif: Email: kash@kashkhanofficial.com Website: https://kashkhanofficial.com/ Reach out to us at: Website: https://gladdenlongevity.com/ Facebook: https://www.facebook.com/Gladdenlongevity/ Instagram: https://www.instagram.com/gladdenlongevity/?hl=en LinkedIn: https://www.linkedin.com/company/gladdenlongevity YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw Gladden Longevity Podcast Disclosures Production & Independence The Gladden Longevity Podcast and Age Hackers are produced by Gladden Longevity Podcast, which operates independently from Dr. Jeffrey Gladden's clinical practice and research at Gladden Longevity in Irving, Texas. Dr. Gladden may serve as a founder, advisor, or investor in select health, wellness, or longevity-related ventures. These may occasionally be referenced in podcast discussions when relevant to educational topics. Any such mentions are for informational purposes only and do not constitute endorsements. Medical Disclaimer The Gladden Longevity Podcast is intended for educational and informational purposes only. It does not constitute the practice of medicine, nursing, or other professional healthcare services — including the giving of medical advice — and no doctor–patient relationship is formed through this podcast or its associated content. The information shared on this podcast, including opinions, research discussions, and referenced materials, is not intended to replace or serve as a substitute for professional medical advice, diagnosis, or treatment. Listeners should not disregard or delay seeking medical advice for any condition they may have. Always seek the guidance of a qualified healthcare professional regarding any questions or concerns about your health, medical conditions, or treatment options. Use of information from this podcast and any linked materials is at the listener's own risk. Podcast Guest Disclosures Guests on the Gladden Longevity Podcast may hold financial interests, advisory roles, or ownership stakes in companies, products, or services discussed during their appearance. The views expressed by guests are their own and do not necessarily reflect the opinions or positions of Gladden Longevity, Dr. Jeffrey Gladden, or the production team. Sponsorships & Affiliate Disclosures To support the creation of high-quality educational content, the Gladden Longevity Podcast may include paid sponsorships or affiliate partnerships. Any such partnerships will be clearly identified during episodes or noted in the accompanying show notes. We may receive compensation through affiliate links or sponsorship agreements when products or services are mentioned on the show. However, these partnerships do not influence the opinions, recommendations, or clinical integrity of the information presented. Additional Note on Content Integrity All content is carefully curated to align with our mission of promoting science-based, ethical, and responsible approaches to health, wellness, and longevity. We strive to maintain the highest standards of transparency and educational value in all our communications.
Learn how histamine and perimenopause create a perfect storm. Doctor Motley interviews Dr. Meg Mill about everything you need to know about histamines, and how to deal with them, at this stage of life. Chapters 02:47 Dr. Meg's Journey from Pharmaceutical Doctorate to Functional Medicine 05:38 Understanding Histamine and Its Role in Health 08:35 The Impact of Gut Health on Histamine Levels 11:37 Methylation and Its Connection to Histamine 14:23 Genetics, Environment, and Individual Health 17:21 Optimizing Health Through Personalized Approaches 21:47 Personalized Health Approaches 25:04 Understanding Histamine and Hormonal Balance 28:55 Practical Steps for Managing Histamine Intolerance 32:39 The Journey of Healing and Compliance 37:33 Connecting Mind, Body, and Spirit in Health Want more of the Ancient Health Podcast? Check out Doctor Motley's YouTube channel! ------ Follow Doctor Motley Instagram TikTok Facebook Website Follow Dr. Meg Mill Website: https://megmill.com/ Instagram: https://shorturl.at/ZICAM Meg's free guide to histamine intolerance: https://go.megmill.com/histamine Meg's A Little Bit Healthier podcast: https://megmill.com/podcasts/ ------ * Do you have a ton more in-depth questions for Doctor Motley? Are you a health coach looking for more valuable resources and wisdom? Join his membership for modules full of his expertise and clinical wisdom on so many health issues, plus bring all your questions to his weekly lives! Explore it free for 15 days at https://www.doctormotley.com/15 *Build Strength Without the Strain. Suji is a smart, wearable device that helps you rebuild strength, relieve pain, and recover faster - without the joint stress. Visit trysuji.com and use code DRMOTLEY for your exclusive discount. * Y'all… not all Vitamin C is created equal.
This episode is brought to you by Joi & Blokes, Troscriptions, and Caldera Lab. In this episode of Ever Forward Radio, registered dietitian Ashley Koff, RD breaks down the truth behind GLP-1 medications like Ozempic and Wegovy, reframing them not as magic weight-loss shots but as hormone replacement therapies that reveal how dysfunctional most people's "weight-health hormones" have become. Ashley shares how digestion, nutrient status, genetics, and modern environmental pressures diminish the body's natural ability to regulate appetite, cravings, metabolism, and fat distribution — and why GLP-1 drugs can offer clarity but not a cure unless the underlying issues are addressed. She dives into muscle preservation, the limitations of BMI, the importance of fat-mass vs. scale weight, the root-cause approach to sustainable weight health, and what the future of GLP-1s means for generational wellness. This is a powerful conversation that blends science, personal insight, and actionable strategies to improve metabolic health — with or without medication. Follow Ashley @ashleykoffapproved Follow Chase @chase_chewning ----- 00:00 – GLP-1 hype: weight loss, risks, and whole-body benefits 02:00 – What GLP-1 drugs actually do in the body 02:20 – Understanding "weight-health hormones" 03:00 – Why society is functioning with suboptimal hormones 12:00 – Why total weight doesn't matter — muscle, fat, and bone do 14:00 – BMI is broken and misleading 15:00 – Weight regain, muscle loss, and metabolism 17:00 – Genetics, survival traits, and appetite regulation 23:00 – Root-cause approach: digestion, nutrient status, vagus nerve work 26:00 – How GLP-1s validate hormone dysfunction 28:00 – Side effects like nausea and constipation explained 30:00 – Why digestive repair is essential for long-term success 33:00 – How GLP-1s quiet obsessive thoughts, cravings, and food noise 36:00 – Supplements that support GLP-1 and weight-health hormone function 38:00 – Hop extract research and natural "GLP-1 activators" 42:00 – Limitations of natural alternatives vs. true hormone replacement 1:12:00 – Glucose spikes, CGMs, and metabolic flexibility 1:27:00 – The future of GLP-1s and redefining "obesity" 1:28:00 – Generational weight health and epigenetics 1:29:00 – Final thoughts and Ashley's Ever Forward message ----- Episode resources: Get 50% off any diagnostic labs with code CHASE at https://www.JoiAndBlokes.com/chase Try CALM and save with checkout code EVERFORWARD at https://www.Troscriptions.com/everforward Get 20% off the best men's skincare with code EVERFORWARD at https://www.CalderaLab.com Watch and subscribe on YouTube Get Ashley's book on Amazon