Podcasts about california san francisco ucsf

In this episode, Dr. Adam Rinde sits down with integrative medicine specialist Dr. Carla Kuon from University of California San Francisco (UCSF) to explore the latest insights into long COVID, chronic fatigue syndrome, and post-viral illnesses. Dr. Kuon shares powerful breakthroughs from her clinical work and research—especially around mitochondrial health and how overlooked deficiencies in riboflavin (B2) and iron (ferritin) can disrupt the body's energy systems.You'll learn how chronic inflammation, nervous system dysregulation, and “bad programming” in the brain are key components of these conditions—and how holistic strategies like nutrient therapy, mindfulness, and vagus nerve stimulation are helping patients recover.Whether you're a patient, provider, or just curious about the future of functional medicine, this conversation is full of takeaways and hope.

Join Elevated GP: www.theelevatedgp.com Free Class II Masterclass - Click Here to Join Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Dr. Stanley Liu (“Leo”) received his undergraduate education from Stanford University. He completed DDS and MD degrees, with General Surgery internship and Oral & Maxillofacial Surgery residency, from the University of California – San Francisco (UCSF). After Sleep Surgery Fellowship at Stanford Medical School in 2014, he was appointed faculty in the Department of Otolaryngology until 2023. He rose to the rank of Associate Professor, and Director of the Sleep Surgery Fellowship. Concurrently, he was a Preceptor of the Oculoplastic Surgery Fellowship and held a courtesy appointment to the Division of Plastic & Reconstructive Surgery.  In February 2024, he joined Nova Southeastern University as the Chair of the Department of Oral & Maxillofacial Surgery, and Assistant Dean of Hospital Affairs. Dr. Liu is a Fellow of the American College of Surgeons (FACS), and the American College of Oral & Maxillofacial Surgeons. He has been a Howard Hughes Medical Institute (HHMI) Scholar, and Stanford Biodesign Faculty Fellow. He serves on the board or executive positions of the California Sleep Society (CSS), American Academy of Physiologic Medicine & Dentistry (AAPMD), and the World Dentofacial Sleep Society (WDSS). He is a consultant member in the sleep section of the American Academy of Otolaryngology – Head & Neck Surgery (AAO-HNS). Dr. Liu's clinical and research focus are on surgical approaches to obstructive sleep apnea. With his surgical mentor and sleep surgery pioneer, Dr. Robert Riley, the Stanford Sleep Surgery approach was updated to integrate drug-induced sleep endoscopy (DISE), nasal surgery including maxillary expansion (DOME), pharyngeal surgery (UPPP), hypoglossal nerve stimulation (HGNS), and maxillomandibular advancement (MMA).  His bibliography lists over 90 journal articles and 20 book chapters. He has been a Grand Rounds speaker at academic programs including UCSF, Northwestern, OHSU, LSU, and Stanford. He has been a Keynote Speaker for preeminent sleep and surgery meetings, including the 33rd SLEEP in 2019, and World Sleep in 2023.

Early detection is a top priority in the field of Alzheimer's research, and one indicator of Alzheimer's disease is the buildup of tau in the brain. What is tau, though? How can we detect this protein, and what can it tell us about a person's symptoms or disease progression? Dr. Gil Rabinovici, a leader in the field of brain imaging, joins Dementia Matters this week for an in-depth discussion on the role of tau PET scans in Alzheimer's disease detection, research and clinical care. Guest: Gil Rabinovici, MD, professor, Department of Neurology, University of California San Francisco (UCSF), director, UCSF Alzheimer's Disease Research Center, study chair, Imaging Dementia-Evidence for Amyloid Scanning (IDEAS) and New IDEAS studies, co-principal investigator, Alzheimer's Network for Treatment and Diagnostics (ALZ-NET), Longitudinal Evaluation of Alzheimer's Disease Study (LEADS) Show Notes Are you a clinician interested in receiving continuing education (CE) credits for listening to this episode? Find credit designation information, disclosures and evaluation information on our website and on the UW–Madison Interprofessional Continuing Education Partnership (ICEP) website. The accreditation for this course expires 4/7/2026. After this date, you will no longer be able to access the course or claim credit. Read “Criteria for Diagnosis and Staging of Alzheimer's Disease,” mentioned by Dr. Rabinovici at 18:43, on the Alzheimer's Association's website. Listen to our past episode with Dr. David Wolk, “LATE, Explained,” mentioned by Dr. Rabinovici at 26:31 on Spotify, Apple Podcasts and on our website. Connect with us Find transcripts and more at our website. Email Dementia Matters: dementiamatters@medicine.wisc.edu Follow us on Facebook and Twitter. Subscribe to the Wisconsin Alzheimer's Disease Research Center's e-newsletter. Enjoy Dementia Matters? Consider making a gift to the Dementia Matters fund through the UW Initiative to End Alzheimer's. All donations go toward outreach and production.

  Join Elevated GP: www.theelevatedgp.com Free Class II Masterclass - Click Here to Join Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Dr. Stanley Liu (“Leo”) received his undergraduate education from Stanford University. He completed DDS and MD degrees, with General Surgery internship and Oral & Maxillofacial Surgery residency, from the University of California – San Francisco (UCSF). After Sleep Surgery Fellowship at Stanford Medical School in 2014, he was appointed faculty in the Department of Otolaryngology until 2023. He rose to the rank of Associate Professor, and Director of the Sleep Surgery Fellowship. Concurrently, he was a Preceptor of the Oculoplastic Surgery Fellowship and held a courtesy appointment to the Division of Plastic & Reconstructive Surgery.  In February 2024, he joined Nova Southeastern University as the Chair of the Department of Oral & Maxillofacial Surgery, and Assistant Dean of Hospital Affairs. Dr. Liu is a Fellow of the American College of Surgeons (FACS), and the American College of Oral & Maxillofacial Surgeons. He has been a Howard Hughes Medical Institute (HHMI) Scholar, and Stanford Biodesign Faculty Fellow. He serves on the board or executive positions of the California Sleep Society (CSS), American Academy of Physiologic Medicine & Dentistry (AAPMD), and the World Dentofacial Sleep Society (WDSS). He is a consultant member in the sleep section of the American Academy of Otolaryngology – Head & Neck Surgery (AAO-HNS). Dr. Liu's clinical and research focus are on surgical approaches to obstructive sleep apnea. With his surgical mentor and sleep surgery pioneer, Dr. Robert Riley, the Stanford Sleep Surgery approach was updated to integrate drug-induced sleep endoscopy (DISE), nasal surgery including maxillary expansion (DOME), pharyngeal surgery (UPPP), hypoglossal nerve stimulation (HGNS), and maxillomandibular advancement (MMA).  His bibliography lists over 90 journal articles and 20 book chapters. He has been a Grand Rounds speaker at academic programs including UCSF, Northwestern, OHSU, LSU, and Stanford. He has been a Keynote Speaker for preeminent sleep and surgery meetings, including the 33rd SLEEP in 2019, and World Sleep in 2023.

In a recent episode of Oncology on the Go, several oncologists discussed the impact of the COVID-19 pandemic on oncology care, 5 years later. Each doctor discussed a different aspect of multidisciplinary care, including medical oncology, radiation oncology, and epidemiology. CancerNetwork® spoke with leading clinicians including:  ·      Aditya Bardia, MD, MPH, FSCO, professor in the Department of Medicine, Division of Hematology/Oncology, and director of Translational Research Integration at the University of California Los Angeles Health Jonsson Comprehensive Cancer Center; ·      Ritu Salani, MD, director of Gynecologic Oncology at the University of California Los Angeles, and ONCOLOGY® editorial advisory board member; ·      Scarlett Lin Gomez, PhD, MPH, a professor in the Department of Epidemiology and Biostatistics at the University of California San Francisco (UCSF), and co-leader of the Cancer Control Program at UCSF Helen Diller Family Comprehensive Cancer Center ·      Marwan F. Fakih, MD, professor in the Department of Medical Oncology & Therapeutics Research, associate director for Clinical Sciences, medical director of the Briskin Center for Clinical Research, division chief of GI Medical Oncology, and co-director of the Gastrointestinal Cancer Program at City of Hope Comprehensive Cancer Center; ·      Elizabeth Zhang-Velten, MD, a radiation oncologist at Keck Medicine of University of Southern California;  ·      Frances Elain Chow, MD, neuro-oncologist at the University of Southern California (USC) Norris Comprehensive Cancer Center ·      James Yu, MD, MHS, FASTRO, assistant professor adjunct, Department of Radiation Oncology, Smilow Cancer Hospital at Saint Francis Hospital, and ONCOLOGY® editorial advisory board member.  The COVID-19 pandemic disrupted routine cancer care in a number of ways. Many patients were unable to receive timely screening, diagnosis, and treatment, Fakih noted. Additionally, Bardia stated that the pandemic led to a decrease in the number of patients participating in clinical trials. One of the most significant changes in oncology care, according to Salani, has been the increased use of telehealth. Telehealth has allowed patients to receive care from the comfort of their own homes, which has been especially beneficial for patients who live in rural areas or who have difficulty traveling. Telehealth has also made it easier for patients to connect with their doctors and to receive support from other members of their care team.  For Gomez, the COVID-19 pandemic also highlighted the importance of addressing the structural and social drivers of health. These are the conditions in which people are born, grow, live, work, and age that can affect their health. For example, people who live in poverty or who lack access to healthy food are more likely to develop cancer. The pandemic has led to a renewed focus on addressing these disparities. Overall, the COVID-19 pandemic has had a profound impact on oncology care. However, it has also led to a number of positive changes, such as the increased use of telehealth and the focus on addressing the structural and social drivers of health. In the years to come, it will be important to continue to build on these changes in order to improve the lives of patients with cancer.

With the recent surge in artificial intelligence and machine learning technology, one of the most exciting fields it could revolutionize is health care and, more specifically, the field of cognitive care and research. Dr. Marina Sirota and Alice Tang join the podcast to share their research on how AI could be used to predict one's risk of developing Alzheimer's disease based on their electronic health records. They also discuss what needs to be done to improve these algorithms and other ways this technology could be used in Alzheimer's disease research. Guests: Marina Sirota, PhD, associate professor, University of California San Francisco (UCSF), principal investigator, Sirota Lab, and Alice Tang, MD/PhD student, University of California San Francisco, postdoctoral fellow, Sirota Lab Show Notes Read Alice Tang and Dr. Sirota's study, “Leveraging electronic health records and knowledge networks for Alzheimer's disease prediction and sex-specific biological insights,” online through the journal Nature.. Learn more about Sirota Lab on their website. Learn more about Dr. Sirota on her UCSF profile. Connect with us Find transcripts and more at our website. Email Dementia Matters: dementiamatters@medicine.wisc.edu Follow us on Facebook and Twitter. Subscribe to the Wisconsin Alzheimer's Disease Research Center's e-newsletter. Enjoy Dementia Matters? Consider making a gift to the Dementia Matters fund through the UW Initiative to End Alzheimer's. All donations go toward outreach and production.

In today's episode, we had the pleasure of speaking with Alan P. Venook, MD, about recent updates to the National Comprehensive Cancer Network (NCCN) Clinical Practice Guidelines for gastrointestinal (GI) cancers. Dr Venook holds the Madden Family Distinguished Professorship in Medical Oncology and Translational Research and is a professor in the Department of Medicine (Hematology/Oncology) at the University of California San Francisco (UCSF). He is also the Shorenstein Associate Director for Program Development at the UCSF Helen Diller Family Comprehensive Cancer Center.

We know healthcare means hospitals and stethoscopes, and x-rays, and bloodwork, and prescriptions. But Dr. Dean-David Schillinger says stories are the key to healthcare—both our willingness to tell them; and our caregiver's ability to listen and understand them. Schillinger is a primary care physician, scientist, author, and public health advocate. He has served as chief of the UCSF Division of General Internal Medicine at San Francisco General Hospital, and chief of the Diabetes Prevention and Control Program for the California Department of Public Health.  He is an internationally recognized expert in health communication and has been widely recognized for his work related to improving the health of marginalized populations.  Schillinger is credited with a number of discoveries in primary care and health communication and is considered a pioneer of the field of health literacy. He is the inaugural recipient of the Andrew B. Bindman Professorship in Primary Care and Health Policy at the University of California San Francisco (UCSF).See omnystudio.com/listener for privacy information.

Findings from a new study support a body of evidence showing that physical exercise can bring benefits to patients with advanced prostate cancer. Data from an intervention study reported at the AACR Annual Meeting 2024 are consistent with mounting epidemiological evidence showing that regular physical exercise can help patients with advanced or metastatic prostate cancer “deter” death, slow disease progression, and improve quality of life. Stacey A. Kenfield, ScD, Professor of Urology and the Helen Diller Family Chair in Population Science for Urologic Cancer at the University of California San Francisco (UCSF), reported early data from the INTERVAL-GAP4 trial. Together with her colleague, June Chan, ScD, Professor of Epidemiology & Biostatistics in Urology at UCSF, she called into the Oncology Times studio at the San Diego conference to tell OncTimesTalk anchor, Peter Goodwin, about the newest findings and recommendations for using physical exercise as a form of therapy for patients with prostate and other cancers.

Join Dr. Ari Hoffman, an influential figure in healthcare and technology, as he shares his expertise and insights on improving healthcare systems and advancing technology in the field. Dr. Hoffman is the Chief Clinical Officer and Vice President at Collective Health. He also held pivotal roles at the University of California San Francisco (UCSF), including the UCSF Division of Hospital Medicine, and as medical director of the UCSF hospital medicine service at St. Mary's Medical Center.   With a background in biological sciences and medicine, Dr. Hoffman brings a unique blend of clinical expertise and technological innovation to the forefront of healthcare. His career journey has seen him contribute to health policy development at prestigious institutions like the NIH and the Center for Medical Technology Policy. In this episode, Dr. Hoffman explores the convergence of clinical practice and health technology. He discusses strategies for improving healthcare delivery, navigating health policy challenges, and leveraging technology to enhance patient care.  Do you have any thoughts or guest suggestions? Please email us at hello@rosenmaninstitute.org.

Kevan M. Shokat is Professor in the Department of Cellular and Molecular Pharmacology at the University of California San Francisco (UCSF), Professor in the Department of Chemistry at the University of California Berkeley (UCB), and an Investigator with the Howard Hughes Medical Institute (HHMI). In this episode of Back of the Napkin reveals the pivotal moments and influences that have shaped his career as an academic and an entrepreneur.The conversation takes us from Kevan's early interest in chemistry, spurred by his childhood experiences in his parents' print shop, to the present day, where his laboratory at UCSF is pushing the boundaries of what was once deemed impossible in targeting key oncogenes. Listeners will discover the compelling story of a scientist whose relentless quest has been to break down fantastical goals into attainable, logical steps. This episode not only captures Kevan's intellectual odyssey but also underscores the power of interdisciplinary thinking and steadfast perseverance in unraveling nature's deepest mysteries.Follow Kevan: @kevansfFollow Alex: @MoloneyAlex

Siyamak sits down with Professor Robin Carhart-Harris from the University of California San Francisco (UCSF) to explore decriminalizing psychedelic drugs in California. "With this massive scaling up, can we ensure the kind of safety and efficacy that we've seen in these small trials? It's a really valid question." ⭕️Watch in-depth videos based on Truth & Tradition at Epoch TV

With American healthcare representing 10% of U.S. carbon emissions, decarbonizing hospitals and healthcare systems promises to deliver meaningful climate action. In this episode, Barbara brings listeners inside an innovative project reducing energy usage in imaging at University of California San Francisco (UCSF). The solutions will not only help to support decarbonization but yield immediate operational savings for hospitals and healthcare systems recovering financially from the pandemic. Guests are Dr. Sean Woolen, USCF's Assistant Professor for Department of Radiology and Biomedical Imaging and Director of the Green Radiology, and Jerry Lawson, Global Head of Digital Portfolio for Healthcare and Life Science, Siemens Smart Infrastructure. Show notes: Study results: https://www.siemens-healthineers.com/en-us/press-room/press-releases/greenradiology Smart healthcare: https://www.siemens.com/us/en/markets/healthcare.html Press release: https://www.siemens.com/us/en/company/press/siemens-stories/usa/siemens-helps-put-sustainability-forefront-medical-imaging-care.html

On this week's episode, WHOOP VP of Performance Science, Principal Scientist, Kristen Holmes is joined by Elissa Epel, Ph.D., professor and vice chair of the Department of Psychiatry at the University of California San Francisco (UCSF) and the author of the book entitled The Stress Prescription. She studies how self-care practices such as meditation and positive stress can promote psychological and physiological thriving and is interested in large-scale interventions for communal well-being and health equity. Kristen and Elissa will discuss the difference between stress, anxiety, and depression (3:25), the perception of stress and your mindset (6:22), the ability to identify stress (12:55), the physiological impacts of stress (16:45), how mindset impacts stress and coping mechanisms (20:20), tools to increase our stress resilience (23:15), the traps of modernity (28:30), maternal lifetime stress exposure and telomere aging (33:32), stress impacting nutrition and overeating (37:41), the ideology of Skillful Surfing (42:58), and sleep strategies (44:49).Resources:The Stress PrescriptionSupport the show

Dr. Lowenthal is a Board Certified Family Physician specializing in eating disorder care for children, adolescents and adults. Utilizing a social justice, Health At Every Size (HAES) lens, Dr. Lowenthal is in private practice in the San Francisco Bay Area and cares for individuals of all genders, sizes, shapes and abilities and at any stage of their recovery. Dr. Lowenthal completed medical school at the University of Chicago and residency at the University of California San Francisco (UCSF). She is one of few primary care physicians nationwide who has been designated by the International Association of Eating Disorder Professionals (IAEDP) as a Certified Eating Disorders Specialist (CEDS) as well as an IAEDP-Approved supervisor for other professionals in the field (CEDS-S).  She is a formerMedical Liaison to and Board Member of the IAEDP SF Bay Area Chapter and a member of the Academy of Eating Disorders.   We discuss topics including: The importance of asking lots of questions The importance to validate what someone is struggling with Going through her own medical conditions has helped her be more humble and compassionate A lot of things can look like IBS and SIBO Understanding gastroparesis   SHOW NOTES: www.sarahlowenthalmd.com   ___________________________________________ If you have any questions regarding the topics discussed on this podcast, please reach out to Robyn directly via email: rlgrd@askaboutfood.com You can also connect with Robyn on social media by following her on Facebook, Instagram, Twitter, and LinkedIn. If you enjoyed this podcast, please leave a review on iTunes and subscribe. Visit Robyn's private practice website where you can subscribe to her free monthly insight newsletter, and receive your FREE GUIDE “Maximizing Your Time with Those Struggling with an Eating Disorder”. Your Recovery Resource, Robyn's new online course for navigating your loved one's eating disorder, is available now! For more information on Robyn's book “The Eating Disorder Trap”, please visit the Official "The Eating Disorder Trap" Website. “The Eating Disorder Trap” is also available for purchase on Amazon.

On this episode of Investor Connect, Hall welcomes Dr. Chris Apfel, Founder, CEO, & Chairman of the Board at SageMedic Corp. Located in Palo Alto, CA, USA, SageMedic Corp. (SAGE) is a cancer diagnostic company that brings precision medicine to the next level by overcoming the limitations of genomic testing. Specifically, because only 1 out of 4 patients have genomic mutations, in most cases oncologists don't have the tools to predict which therapy, if any, is likely to work for an individual patient. Hence, SAGE has developed the SAGE Oncotest™, a proprietary patent-protected ex-vivo, high-throughput 3D assay that predicts a patient's tumor response to traditional chemotherapies and targeted therapies, independently of any potential genetic mutations, and that within just 1 week.  With only $4.0M of funding SAGE has been able to develop this assay and is now a registered California lab that has very recently become fully accredited according to the Clinical Laboratory Improvement Amendments (CLIA) by the Commission on Office Laboratory Accreditation (COLA) and Center for Medicare and Medicaid Services (CMS), hence at the verge of starting commercialization to generate early revenue and clinical case studies.  Dr. Chris Apfel is an impact investor, and the Chair of the Life Sciences at the Northern California chapters of the Keiretsu Forum. He has led numerous due diligence efforts and has since made over 20+ investments in life science companies including Mission Bio, CorInnova, Pathware, Raydiant Oximetry, etc.  Before that, Dr. Apfel was an Executive Director of Cadence, where his health economic research on a non-reimbursable drug showed a $500 per patient cost savings after which Cadence was acquired for $1.3 billion by Mallinckrodt. Before he moved into the industry, he was a practicing clinician and professor at the University of California San Francisco (UCSF) with over 100 publications that have been cited over 20,000 times in the literature. Dr. Apfel received his MD/PhD from the University of Giessen, Germany, and his MBA from The Wharton School of Business, University of Pennsylvania, PA.  Dr. Chris shares the need for a strong and experienced team and game-changing technology, while also acknowledging the regulatory challenges in the life science space. He shares his belief that successful FDA approval can lead to high rewards and discusses the significance of reproducibility in academic research and the importance of forming independent opinions when evaluating startup opportunities. Visit SageMedic Corp at , and on . Reach out to Dr. Chris at , and on .   _______________________________________________________ For more episodes from Investor Connect, please visit the site at:    Check out our other podcasts here:   For Investors check out:   For Startups check out:   For eGuides check out:   For upcoming Events, check out    For Feedback please contact info@tencapital.group    Please , share, and leave a review. Music courtesy of .

Dr Sima Porten from the University of California San Francisco (UCSF), was in Melbourne this week for the ANZUP Annual Scientific Meeting (more from that in an upcoming episode), so she popped into the GU Cast studio to chat with Renu and Declan. Renu of course spent a year with Sima and colleagues doing Fellowship training in GU Oncology so she was very happy to have her good friend and mentor in town. Sima is a very highly regarded expert in bladder cancer and delivered some great talks on this topic to the ANZUP ASM this week. We chat with her about strategies to help patients avoid cystectomy (bladder removal) despite refractory high-grade bladder cancer. We also chat about avoiding cystectomy in muscle-invasive bladder cancer, and her thoughts on open vs robotic surgery from her perspective as a very high-volume bladder cancer surgeon. Even better when watched on YouTube 

This week's episode dives into racial disparities in healthcare and the field of urology, with a focus on prostate and bladder cancer. Jonathan and Samuel Washington, University of California San Francisco (UCSF), USA, discuss equality and equity in healthcare, uncovering how racial disparities affect the diagnosis and treatment of urological tumours, particularly in African American men. The pair also speak about which groups are more at risk of experiencing adverse outcomes, the changes needed to ensure better care is available to these patients, and how racial disparities affect medical education. Use the following timestamps to navigate the topics discussed in this episode: (00:00)-Introduction (01:58)-Inspiration which led Washington to work in urologic oncology (02:42)-“Urologic personality” traits (04:01)-Machine-learning algorithms in estimating occurrence of lymph node cancer (06:26)-Dietary and lifestyle factors influencing patient outcomes (08:06)-Healthcare disparities in treating genitourinary diseases (09:45)-Changes needed to make outcomes equivalent for patients of different races (12:52)-Societal and political factors interacting with healthcare (15:04)-Socioeconomic factors impacting healthcare use after bladder removal (16:59)-Equity and equality in healthcare: health literacy and shared decision-making (18:42)-Tailoring patient communications in prostate cancer screening (20:00)-Partner-supported treatment decisions (21:03)-Racial and ethnic differences in medical student training (22:23)-Three wishes for the future of healthcare

Our coverage of Euroanesthesia 2023 continues; The European Society of Anaesthesiology and Intensive Care (ESAIC) is the leading European Organisation for Anaesthesia, Intensive Care, Pain and Perioperative Medicine. TopMedTalk is proud to bring you 'as live' coverage of their annual conference. For more information on the work ESIAC do check out their website here https://euroanaesthesia.org/ Here Desiree Chappell, Monty Mythen and Andy Cumpstey speak to Adrian Gelb, Professor (emeritus) in the Department of Anesthesia & Perioperative Care, University of California San Francisco (UCSF) and Immediate Past President of The World Federation of Societies of Anaesthesiologists (WFSA) and the current president; Wayne Morriss, Clinical Associate Professor, University of Otago, Christchurch and Christian Werner, Chair of Anesthesia at Johannes Gutenberg University in Mainz and WFSA Chair of the Scientific Affairs Committee. We covered The American Society of Anesthesiologists, Global Scholar programme here: https://topmedtalk.libsyn.com/the-asa-global-scholars-program-part-1-anesthesiology-2022 https://topmedtalk.libsyn.com/the-asa-global-scholars-program-part-2-anesthesiology-2022 Find out more about the WFSA here: https://wfsahq.org/

Huberman Lab Podcast Notes Key Takeaways Stress and your perception of stress impact your brain and bodyManaging stress is about finding the ‘stress shields' that fit them, feel right, and they believe – for example, breathwork, reminding yourself of past successes, distance from stress, calling on confidant, etc.Stress can lead to obesity and insulin resistance: there's a tendency to a greater reward response from food – the more insulin resistant you are, the more your reward center lights up during stressCravings hijack the prefrontal cortex – body scan draws attention inward toward interoception and away from external stimulusAt our core, we want to know with certainty what's going to happen and control our future – being comfortable with uncertainty is a huge stress resilience factorTips to navigate stress: journal to create a coherent narrative; practice radical acceptance, learning when to paddle and when to give into the wave; practice breathwork and body scans to increase interoception and reduce exteroception; use exercise to burn negative energy and improve stress resilienceRead the full notes @ podcastnotes.orgIn this episode, my guest is Elissa Epel, Ph.D., professor and vice chair of the department of psychiatry at the University of California San Francisco (UCSF) and the author of a new book entitled The Stress Prescription. We discuss her work showing how stress impacts mood, eating behavior, mental health, physical health, and aging. She explains stress intervention tools using “top-down” techniques (e.g., radical acceptance, mindfulness, reframing), body-based methods (e.g., breathwork) including the Wim Hof Method, exercise, meditation, body scans, and environmental shifts proven to help people cease unhealthy rumination patterns. We discuss how stress can positively impact psychology and sense of purpose, how stress affects cellular aging, how our narratives of stressful events impact our mood and biology, and how to effectively reframe stress. She explains science-based techniques to break stress-induced cycles of craving and overeating and thereby improve insulin sensitivity and metabolic health. Dr. Epel provides a wide range of tools shown to be effective in reducing stress and improving various aspects of our health. For the full show notes, visit hubermanlab.com. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Thesis: https://takethesis.com/huberman Eight Sleep: https://eightsleep.com/huberman HVMN: https://hvmn.com/huberman InsideTracker: https://www.insidetracker.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman Timestamps (00:00:00) Dr. Elissa Epel (00:02:17) Sponsors: Thesis, Eight Sleep, HVMN, Momentous (00:06:18) Stress; Effects on Body & Mind (00:12:50) Tools: Overthinking & Stress (00:15:37) Acute, Moderate & Chronic Stress, Breathing (00:21:23) Stress Benefits, Aging & Cognition; Stress Challenge Response (00:31:04) Sponsor: AG-1 (Athletic Greens) (00:32:19) Tool: Shifting Stress to Challenge Response, “Stress Shields” (00:37:400 Stress, Overeating, Craving & Opioid System (00:48:55) Tools: Breaking Overeating Cycles, Mindfulness (00:54:44) Soda & Sugary Drinks (01:00:51) Smoking, Processed Food & Rebellion (01:05:29) Sponsor: InsideTracker (01:06:47) Tools: Mindfulness, Pregnancy & Metabolic Health (01:14:11) Body Scan & Cravings (01:17:28) Tool: Meditation & Aging; Meditation Retreats (01:23:35) Meditation, Psychedelics & Neuroplasticity (01:26:02) Mitochondrial Health, Stress & Mood (01:29:49) Chronic Stress & Radical Acceptance, “Brick Wall” (01:37:57) Tool: Control, Uncertainty (01:45:25) Stress Management, “Skillful Surfing” (01:50:25) Narrative, Purpose & Stress (01:52:49) Breathwork, Wim Hof Method, Positivity & Cellular Aging (02:03:11) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network Newsletter Title Card Photo Credit: Mike Blabac Disclaimer

In this episode, my guest is Elissa Epel, Ph.D., professor and vice chair of the department of psychiatry at the University of California San Francisco (UCSF) and the author of a new book entitled The Stress Prescription. We discuss her work showing how stress impacts mood, eating behavior, mental health, physical health, and aging. She explains stress intervention tools using “top-down” techniques (e.g., radical acceptance, mindfulness, reframing), body-based methods (e.g., breathwork) including the Wim Hof Method, exercise, meditation, body scans, and environmental shifts proven to help people cease unhealthy rumination patterns. We discuss how stress can positively impact psychology and sense of purpose, how stress affects cellular aging, how our narratives of stressful events impact our mood and biology, and how to effectively reframe stress. She explains science-based techniques to break stress-induced cycles of craving and overeating and thereby improve insulin sensitivity and metabolic health. Dr. Epel provides a wide range of tools shown to be effective in reducing stress and improving various aspects of our health. For the full show notes, visit hubermanlab.com. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Thesis: https://takethesis.com/huberman Eight Sleep: https://eightsleep.com/huberman HVMN: https://hvmn.com/huberman InsideTracker: https://www.insidetracker.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman Timestamps (00:00:00) Dr. Elissa Epel (00:02:17) Sponsors: Thesis, Eight Sleep, HVMN, Momentous (00:06:18) Stress; Effects on Body & Mind (00:12:50) Tools: Overthinking & Stress (00:15:37) Acute, Moderate & Chronic Stress, Breathing (00:21:23) Stress Benefits, Aging & Cognition; Stress Challenge Response (00:31:04) Sponsor: AG-1 (Athletic Greens) (00:32:19) Tool: Shifting Stress to Challenge Response, “Stress Shields” (00:37:400 Stress, Overeating, Craving & Opioid System (00:48:55) Tools: Breaking Overeating Cycles, Mindfulness (00:54:44) Soda & Sugary Drinks (01:00:51) Smoking, Processed Food & Rebellion (01:05:29) Sponsor: InsideTracker (01:06:47) Tools: Mindfulness, Pregnancy & Metabolic Health (01:14:11) Body Scan & Cravings (01:17:28) Tool: Meditation & Aging; Meditation Retreats (01:23:35) Meditation, Psychedelics & Neuroplasticity (01:26:02) Mitochondrial Health, Stress & Mood (01:29:49) Chronic Stress & Radical Acceptance, “Brick Wall” (01:37:57) Tool: Control, Uncertainty (01:45:25) Stress Management, “Skillful Surfing” (01:50:25) Narrative, Purpose & Stress (01:52:49) Breathwork, Wim Hof Method, Positivity & Cellular Aging (02:03:11) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network Newsletter Title Card Photo Credit: Mike Blabac Disclaimer

This episode features Dr. Stefano Bini, Professor of Orthopaedic Surgery at University of California, San Francisco (UCSF) & Board Member at StartUp Health. Here, he discusses his background, what he is seeing with artificial intelligence, AR, 3D printing, & robotics in orthopedics, and more.

Nonpharmacologic/nonsurgical interventions for pain relief….. What are they? Did you know they might be your best option for managing your chronic back/hip/joint pains? Dr. Akash Bajaj is our guest today.  He does an amazing job of explaining and simplifying the pain management process. Dr. Bajaj has THREE board certifications! He started off completing an Anesthesiology Residency and then specialized in Pain Management to address chronic pain issues in patients. Years later he realized that many patients reached a plateau with traditional therapy models. This piqued his interest in Functional Medicine/Anti-aging to treat and PREVENT chronic ailments and issues with aging.  Most of all he emphasizes how important MINDSET is to the healing process! Get your lifestyle right and prevent ailments, instead of nursing them back to health! Topics we cover today: 1: What doctors are best for helping with chronic pain , what options are available, what are the most helpful, and when is it time to seek alternative therapies? 2: How does functional Medicine play a role in pain management?  3: What is the role of functional Medicine for helping the body rejuvenate, heal and thrive? 4: How can hormones, diet, lifestyle and supplemental new therapies optimize your health? More about our guest! Dr. Bajaj completed his undergraduate studies at UCSD, graduating summa cum laude and is a member of the prestigious Phi Beta Kappa & Golden Key Honor societies. He then went on to simultaneously earn his M.D. and a Master's degree in Public Health (M.P.H.) from the New York Medical College. While in NYC, he was also a first responder during the 9/11 attack on the World Trade Center. He then served a residency in Anesthesiology at UCLA Medical Center.  He then completed an Interventional Pain Medicine Fellowship at the prestigious University of California San Francisco ( UCSF ) , selected as one of only five fellows. Further enhancing his education, Dr Bajaj then pursued his deepest passion of Anti-Aging Medicine, achieving board certification as well. He has an active practice in Los Angeles helping clients with a unique combination of mindset and medicine . He coaches them to drop their self destructive habits and vices, optimizing physiology with Anti-Aging Techniques, and allowing his clients to FINALLY love and respect who they see in the mirror.  His transformations are astounding! Dr. Bajaj is Triple-Board Certified in Anesthesia, Pain Management, and the American Board of Anti-Aging Medicine. Sponsor: Check out  New Leaf Hyperbarics in Eugene, OR and experience the benefits of hyperbaric therapy! Links! Find Dr. Bajaj here: Website: https://www.thinkrws.com/ Instagram: https://www.instagram.com/akashbajajmd/ Our Advice! Everything in this podcast is for educational purposes only. It does not constitute the practice of medicine and we are not providing medical advice. No Physician-patient relationship is formed and anything discussed in this podcast does not represent the views of our employers.  The Fine Print! All opinions expressed by the hosts or  guests in this episode are solely their opinion and are not to be used as specific medical advice.  The hosts,  May and Tim Hindmarsh MD, BS Free MD LLC, or any affiliates thereof are not under any obligation to update or correct any information provided in this episode. The guest's statements and opinions are subject to change without notice. Thanks for joining us! You are the reason we are here.  If you have questions, reach out to us at doc@bsfreemd.com or find Tim and I on Facebook and IG. Please check out our every growing website as well at  bsfreemd.com (no www)  GET SOCIAL WITH US! Rumble: https://rumble.com/search/video?q=bsfreemd Instagram:: https://www.instagram.com/bsfreemd/ Facebook: https://www.facebook.com/bsfree YouTube Channel: coming soon!

Medical Humanities, editor-in-chief Brandy Schillace speaks to Emily Silverman, MD, the University of California San Francisco (UCSF)creator of The Nocturnist podcast, and Luna Dolezal, Associate Professor in Philosophy and Medical Humanities based in the Wellcome Centre for Cultures and Environments of Health. They both published a 10-part podcast series called 'Shame in Medicine: The Lost Forest'. Blog link with the transcription of this podcast: https://blogs.bmj.com/medical-humanities/2023/03/02/shame-in-medicine-the-lost-forest Related links: https://shameandmedicine.org/ https://thenocturnists.com/ https://www.thenocturnists-shame.org/ Subscribe to the Medical Humanities Podcast in all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify. If you enjoy our podcast, please consider leaving us a review and a 5-star rating on the Medical Humanities Podcast iTunes page (https://podcasts.apple.com/gb/podcast/medical-humanities-podcast/id961667204). Thank you for listening!

Cytopathology Program Director Toolkit: Performance of Fine-Needle Aspiration Biopsies Dr. Vanda Torous, Chair of the ASC Cytopathology Program Directors Committee, interviews Dr. Elham Khanafshar on her experience incorporating the performance of fine needle aspirational biopsies into cytopathology training. Dr. Khanafshar is currently a Professor of Pathology, Director of Cytopathology and Medical Director of FNA Clinic at the University of California San Francisco (UCSF). Dr. Khanafshar was also the program director of the UCSF cytopathology fellowship program from 2012-2020, during which time she implemented a boot camp rotation for the fellows with a focus on teaching interventional cytopathology. She has served on numerous professional organization committees and was a member of the ASC program director committee for two years. Dr. Khanafshar is a dedicated teacher and has contributed significant to the fields of cytopathology and thyroid pathology. For an outline of the talking points and list of references click here.  Sponsored by the ASC Cytopathology Program Directors Committee. 

Ron Balassanian is a Professor of Pathology at the University of California San Francisco (UCSF) with an appointment in UCSF Helen Diller Family Comprehensive Cancer Center. His clinical and research work focuses on fine needle aspiration (FNA) biopsy and general breast pathology, as well as patient communication and global health. Ron has led workshops on training pathologists to perform and interpret ultrasound guided FNA for the College of American Pathologists, the American Society of Cytopathology and the United States and Canadian Academy of Pathology. In collaboration with PATH, a Seattle based NGO, he helped develop the Community Program for Breast Health in Trujillo Peru, using FNA as a cost-effective tool for diagnosis and triage. Through the UCSF Global Cancer Program, he helped develop an US-FNA course in Dar es Salaam Tanzania as part of an ongoing educational collaboration between Muhimbili University and the UCSF Global Cancer Program. At UCSF he developed a patient education program called “Ask Your Pathologist” inviting patients to review their breast cancer slides with a Pathologist to better understand their pathology report. In his clinical service and research work, Ron is passionate about patient centered pathology and bridging the gap between the patient and the pathologist.  Twitter:  @BalassanianRon

Happy New Year fam! We're back for part two of Season 3. We're not done with the season yet. We've got an amazing guest to kick off the year! In this episode we're joined by the talented and driven, Jaysón Davidson. Jaysón is a Clinical Informatics Research and PhD Candidate in the Pharmaceutical Sciences and Pharmacogenomics program at University of California San Francisco (UCSF). At UCSF, he is a member of Dr. Atul Butte's lab, where he intends to develop methods to effectively stratify the differences in disease and drug response outcomes between populations with different social determinants to improve overall healthcare quality and equity. Jaysón primarily studies treatment utilization, and health outcomes of Type 2 Diabetes patients that are treated within the UC-Health system. If this episode doesn't motivate you to get that late start of the year going, we don't know what will. Listen as we discuss belief in self, trusting others and the process, representation, determination, imposter syndrome, intentionality, and so much more. Be sure to follow Jaysón on social media; dude is destined to great things! As always, be sure to Like, Share, and leave a comment. We are always seeking for new ways to improve and grow our audience. Resources Black in Chem: https://blackinchem.org Twitter: @jayson_davidso7, @BlackInChem LinkedIn: Jaysón Davidson

Description: In this episode, we are joined by Dr. Amy Houtrow. Dr. Houtrow is a pediatric rehabilitation medicine physician, a health services researcher for children with disabilities, and a person with childhood-onset disabilities. In this episode, she joins Dr. Poullos to discuss her career path, her research, and her advice for aspiring healthcare providers with disabilities.  Key Words: pediatrics, education, physical disability, Contra dystrophia calcium cans congenita, scoliosis, visual disability, research, mobility, lung disease, public policy Bio:  Amy Houtrow, M.D., Ph.D., M.P.H., is a professor and the Endowed Chair for Pediatric Rehabilitation Medicine in the Department of Physical Medicine and Rehabilitation at the University of Pittsburgh School of Medicine. She is also Chief of the Pediatric Rehabilitation Medicine Services at the University of Pittsburgh Medical Center (UPMC) Children's Hospital of Pittsburgh (CHP). Dr. Houtrow earned her medical degree at Michigan State University and completed a combined residency program in Pediatrics at Cincinnati Children's Hospital Medical Center and Physical Medicine and Rehabilitation at the University of Cincinnati College of Medicine. She is board certified in Pediatrics, Physical Medicine & Rehabilitation and Pediatric Rehabilitation Medicine. She completed a Master's degree in Public Health in Health Policy and Management at the University of Michigan and earned her Ph.D. with distinction in Medical Sociology at the University of California San Francisco (UCSF) while also serving as faculty there. Her dissertation won an international award for research on childhood disability. Her research has focused on health care access and outcomes for children and youth with disabilities with special emphasis on health equity and the impact of childhood disability on families. She has authored over 140 manuscripts for high-impact medical journals, written and edited textbooks, developed training programs for young physicians, and she is a sought-after speaker for conferences nationally and internationally. Her work has repeatedly garnered national media attention and informed public health policy. In 2018 she was inducted into the National Academy of Medicine, one of the highest honors in medicine. Transcript

This episode is brought to you by BiOptimizers, Rupa Health, and Pendulum. What's the point in living a long time? Being fully in contribution to life. I want to do that feeling healthy and vital, not sick and decrepit. Everything we do speaks to our genes—the food we eat, our relationships, our environment. You're either telling your genes to age faster or age slower. So I'm constantly working on how to give my genes the right information to do the latter. Today's podcast episode was recorded on my recent trip to Antarctica with my own doctor, Dr. Matt Cook. He's helped me heal and has integrated so many different forms of technologies and science to rebuild people's health from the ground up. Dr. Cook is the Founder of BioReset® Medical. He is a board-certified anesthesiologist with over 20 years of experience practicing medicine, focusing the last 14 years on Functional and Regenerative Medicine. He graduated from the University of Washington School of Medicine, completed his anesthesiology residency at the University of California San Francisco (UCSF), and completed a fellowship in Functional Medicine. This episode is brought to you by BiOptimizers, Rupa Health, and Pendulum. BiOptimizers Magnesium Breakthrough formula contains seven different forms of magnesium, all of which have different functions in the body. There is truly nothing like it on the market. Go to magbreakthrough.com/hyman and use code hyman10 at checkout for 10% off your next order.Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com.Pendulum is the first company to figure out how to harness the amazing benefits of Akkermansia in a probiotic capsule. To receive 20% off your first purchase of Pendulum's Akkermansia probiotic supplement, go to Pendulumlife.com and use code MARK20.Here are more details from our interview (audio version / Apple Subscriber version): What's the point of living a long life? (5:38 / 2:23) What I learned from my travel through the Blue Zones (6:36 / 3:25)Five converging trends that will change our thinking about medicine and health (13:33 / 10:16)The root causes of aging (18:16 / 15:02)Influence your genes to reverse your biological age (22:29 / 17:42) How to eat to extend your life span (28:40 / 24:01) Practices and supplements to support healthy aging (35:51 / 31:23) Regenerative medicine therapies and protocols (48:12 / 42:13) What the Yamanaka factors teach us about aging (1:13:12 / 1:08:31) Reimaging how we deal with trauma (1:21:21 / 1:16:49) Learn more about Dr. Matt Cook and his work at BioReset Medical at bioresetmedical.com. See acast.com/privacy for privacy and opt-out information.

Amy S. Peele RN, is the award-winning, best-selling author of Cut and Match, medical mysteries with a mission and a side of humor. Before becoming a writer Amy enjoyed a fascinating 35-year career in the organ transplant field which provides an authentic backdrop to her books. As Director of Clinical Operations at University of California San Francisco (UCSF), Amy oversaw a team that successfully completed over 600 transplants annually. She learned early on in her medical career that humor was an important survival skill and studied improvisation at the world premier school, Second City, in Chicago. Amy is an accomplished speaker who regularly presents to prestigious US medical centers such as, NYU, University of Chicago, University of Michigan and UCLA. She tells her audiences, ‘I kill people I didn't like at work and use their organs for transplant - why waste the kill?' As a certified Chopra Yoga Instructor Amy has been known to infuse her presentations with Chair Yoga which people need now more than ever while working remotely. Match, Amy's latest book, is a page-turning thriller that takes the reader into the vivid and dramatic world of kidney transplantation. Amy expertly weaves politics, living donor kidney transplants & the opioid crisis into a fast-paced, nonstop adventure. Her book, Cut, received many awards, including the 2017 Independent Press Award, The Chanticleer International Book Award, a Pinnacle Book Achievement Award, and a Finalist designation from the 2017 International Book Awards. Amy currently resides in San Francisco, close to the Golden Gate Bridge. Topics covered in this episode: Organ Transplantation Lifestyle Modifier Habits Relief in high stress jobs Meditation techniques Acting training Improv life applications Laughter Yoga Importance of taking time for you Implications of addicts organs Organ shortage Mediation benefits of the brain Referenced in the episode: What Got You Here Won't Get You There by Marshall Goldsmith To learn more about Amy Peele and her work, head over to www.amyspeele.com IG @amypeele __________________________________________________________ Amare Edge Better Mood, Increased Motivation & Supporting a Better Metabolism. Head over to www.lindseyelmore.com/amare to get started. Between now and April 14th you can get a free product credit to get Edge and you will be on your way to improving your brain and body. __________________________________________________________ Primal Life Organics skincare addresses the 5 pillars that help your skin to look healthy, bounce back and have a vibrant complexion. Skin needs to stay hydrated, have good blood flow, good collagen, good elastin and maintain muscle tone. Head to www.lindseyelmore.com/primallife to get the Glow package today and try out Lindsey's new favorite skincare. __________________________________________________________ __________________________________________________________ We hope you enjoyed this episode. Come check us out at www.lindseyelmore.com/podcast

Dr. Liu is as an Associate Professor of Otolaryngology, and by courtesy, of Plastic and Reconstructive Surgery at Stanford University School of Medicine. He is director of the Stanford Sleep Surgery Fellowship, and preceptor to the Stanford Oculoplastic Surgery Fellowship. He is a Stanford Biodesign Faculty Fellow Alumnus. After graduating from Stanford University with a degree in Biology, Dr. Liu received medical and dental degrees from the University of California-San Francisco (UCSF). He was a former Howard Hughes Medical Institute (HHMI) Research Scholar and spent a year at the NIH. After oral and maxillofacial surgery residency at UCSF, he completed the Stanford sleep surgery fellowship in 2014 with the Department of Otolaryngology and sleep surgery pioneer Dr. Robert Riley. Dr. Liu practices the full scope of sleep apnea surgery including nasal, palate, tongue base, hypoglossal nerve stimulation, genioglossus advancement, and maxillomandibular advancement (MMA). He introduced adult maxillary expansion (DOME) for OSA with Professor Christian Guilleminault in 2015, and has continued to update the comprehensive sleep surgery protocol at Stanford. He is also routinely referred patients who need complex facial trauma reconstruction and orthognathic surgery. Dr. Liu's active areas of research include clinical phenotyping to optimize sleep surgery outcome, virtual surgical planning for facial skeletal surgery, and neuromodulation of the upper airway. He has given keynote talks nationally and internationally at preeminent conferences across specialties. He has published over 90 scientific articles and medical texts, with original scientific work on sleep surgery.

We all deserve to get the help we need to be better and to do better. Treating what is happening inside the brain is just as important as treating what is happening outside when someone has sustained brain trauma. The healing process of the brain is affected by the way that we treat it by providing medical, emotional and mental health support.In this episode, Suzi has the pleasure of chatting with Spencer Milo, not only a dear friend but a phenomenal individual. Spencer is the Director of Strategic Development & External Relations at the Marcus Institute for Brain Health (MIBH). The MIBH offers an intensive outpatient treatment program for veterans first responders and retired athletes that have been dealing with the prolonged symptoms of concussion and trauma brain injury.Learn more about MBIH at https://medschool.cuanschutz.edu/mibhContact them directly at https://medschool.cuanschutz.edu/mibh/contact-usSpencer Milo BioSpencer Milo is a medically re​tired, post-9/11 U.S. Army combat veteran and Purple Heart recipient, who served in both Iraq and Afghanistan. A passionate advocate and spokesman for Veterans and Veterans' issues, he also serves transitioning military members and Veterans in his civilian career today.An Airborne Infantryman who was recognized as an exceptional leader in combat, Spencer held a number of command and control roles in military assignments that spanned the United States, Europe and Asia, in addition to the Iraq and Afghanistan conflicts.In 2008, during a 16-month tour in Iraq where he saw action in Baghdad and Mosul, Spencer suffered a concussion and other minor injuries when a routine convoy of U.S. Humvees encountered small arms fire. It was while evading enemy contact that he got tossed around inside the turret, and his vehicle crashed. One year later, he was told by doctors stateside that his injury had caused a brain tumor and was given a 6-month terminal diagnosis. Heavily medicated and bedridden for months, he started having seizures. After his family fought for a second opinion, he was sent to the University of California San Francisco (UCSF), where he was eventually told he had been misdiagnosed.Cleared back for duty in January 2010, Spencer chose to continue following his passion for military service and he deployed soon after to Afghanistan. Less than a year later, in January 2011, he was on combat patrol in Spin Boldak, a district in Kandahar Province. That's when an Afghan boy, who stood just feet away from Spencer, detonated himself as a suicide bomber. Thrown 15- 20 feet by the blast, he charged back into the smoke to find his wounded platoon buddy and drag him to safety. Among his injuries: small amounts of shrapnel to his left side and his face; injuries to his spine; hearing loss; Post Traumatic Stress; and, Traumatic Brain Injury. Spencer was returned to the states for medical treatment at Fort Bragg and, after 6 months, he was transferred to the National Intrepid Center of Excellence (NICoE) at Walter Reed Bethesda, where he underwent four weeks of intensive treatments. Spencer was medically retired as a result of his injuries.Suzi Landolphisuzigma@gmail.comwww.suzilandolphi.comBe Crazy Well is a Coming Home Well Podcast.Make sure to subscribe, leave a review and share with a friend!Music credit to Kalvin Love for the podcast's theme song “Bee Your Best Self”

In this episode, Mallory talks with Dr. Nicquet Blake, Vice Provost of Student Academic Affairs and Dean of the Graduate Division at the University of California-San Francisco. Dr. Blake discusses her passion for diversity in education, the benefits of holistic admissions, and the potential long-term impacts the pandemic will have on our entire educational system and how to perhaps avoid them.

On this episode of the I Look Like a Doctor podcast, I had the pleasure of interviewing Dr. Mauricio "Jimmy" Franco. He is a pediatrics resident (PGY1) at the UCSF-PLUS pediatrics residency. During our discussion about Dr. Franco's background and journey to medicine, we touched on many amazing and high-yield topics. Tune in to hear us talk about non-linear journeys, working during pre-med, finances, GPA, MCAT, medical school application experience, study strategies, finding your narrative, wellness, moving away from home, choosing a non-science major, multi-faceted identities, building your dream mentor team, personal statement writing, and more! This is a longer episode than usual but well worth the listen.Short Bio as written by Dr. Franco:My name is Mauricio “Jimmy” Franco, I was born in Los Angeles and grew up in Lancaster, CA. I am the brother of three strong mujeres and the son of Guatemalan immigrants. This mezcla of identities and experiences has helped mold me into an outspoken Queer Centro Americano.Beyond my role in medicine, l I am a writer, photographer, and activist. Finding balance in my life through community work, wellness, and family has helped me sustain my commitment to achieving a career in medicine while also nurturing my full self. I have carved a path that centers on social justice and health equity as the backbone to how I approach medicine as well as mentorship. I spent 15 plus years co-leading initiatives to transform mentorship in Latinx communities and LGBTQIA+ advocacy. My life's mission is to support those around me to live authentically and to uplift the many journey's a person can have in becoming a physician. If you are struggling with imposter syndrome know this; I graduated undergrad with a 2.57 GPA, completed a postbacc program, took the MCAT twice, completed a Master of Science in Global Medicine, and applied to Medical school twice before being admitted to medical school. I believe our journeys have the power to transform medicine and uplift others to live without shame. Medical school had its challenges, but I am proud of what I have accomplished and carry the many lessons I have learned from the communities I serve. After graduation from Michigan State University College of Human Medicine, I will be training as a pediatrician. I matched at the University of California San Francisco (UCSF) where I will continue to learn how to integrate health equity and public health into my role as a physician. Medicine needs to be radically transformed and I am grateful to my mentors for showing me that I can be a queer Guatemalan and show up as my full self wherever I go.Music by Francis TongpaladCheck out the rest of his work:Soundcloud - https://soundcloud.com/1w_uSpotify - https://open.spotify.com/artist/3VwEfXzbnf11lhaYAuuMtUApple Music - https://music.apple.com/us/artist/w-u/1526729708Bandcamp - withuu.bandcamp.comAudius - https://audius.co/1w_u

Want the Ditch The Diet Guide? Click here and get the guide for FREE. Do you have healthy, radiant skin?Have you considered your lifestyle as making your skin disease worse?Join me as I chat with Kemunto (Kemmy) Mokaya, MD (@drkemmymd). Kemunto Mokaya, M.D. (a.k.a. Dr. Kemmy) is a highly respected board-certified dermatologist,mindset coach, and speaker. She was born in Nairobi, Kenya, and moved to the United Statesfor undergraduate studies at Yale University. She graduated from the Yale School of Medicinewith her Doctor of Medicine degree (MD) and master's degree in Health Science (MHS). Shecompleted her Internal Medicine internship at the Harvard-affiliated Massachusetts GeneralHospital. Her Dermatology residency was at the University of California San Francisco (UCSF). As a mindset coach, she has empowered many women to achieve their dreams. She is also an international speaker, author, and podcaster. Dr. Kemmy speaks dynamically on all matters related to skin and mindset in conferences, corporations, churches, and universities. She is a best-selling author, and the host of the Live and Look Younger podcast. She is also a blogger and a prolific media expert who contributes to publications like the Huffington Post, Healthline, NBC, Ebony, and many others.Her new book, Live and Look Younger, releases in November. “It is possible to live a limitless life to its full potential! While you're at it, get your glam on and glow inside and outside!” - Dr. KemmyIn this episode we chat about:How growing up in Kenya drove her to be a woman in medicine.How do lifestyle medicine shifts make dermatological conditions better?Lifestyle tips for women with PCOS.The power of getting your nutrients through food not supplements.Her skincare tips on what to use for getting beautiful skin. Why we should focus on lifestyle changes and not quick fixes. What happens with our skin in pregnancy and how you can make your skin radiant. Thank you so much for tuning in to this episode. I'm beyond honored that you're here and would be grateful if you could take 2 minutes to leave me a 5-star review in iTunes or on your podcast app, this way together we can inspire, connect and educate even more women.Let's connect? Take a screenshot of this episode and share it on Instagram tagging me in with Jennifer Roelands, MD │Coach (@wellwomanmd) • Instagram photos and videos and the hashtag #WellWomanMD – can't wait to connect.Here is Dr. Kemmy's info.Kemunto (Kemmy) Mokaya, MD (@drkemmymd) • Instagram photos and videosResources I mention:Ditch The Diet GuideIt's time to ditch the diets and find out what works for YOUR PCOS. In this guide, I will bust the myths surrounding what women with PCOS should eat. And give you a 5-day meal plan with easy recipes for the busy week.THANK YOU TO OUR  SPONSOR:Want to learn why your hormones are a hot mess? Trying to get pregnant and want answers?

https://bengreenfieldfitness.com/cook He's back... ...one of my most popular podcast guests of all time. I recently flew down to Dr. Matthew Cook's office in San Jose, at a location called BioReset™️ Medical, for a cutting-edge knee repair protocol, similar to the type of new knee and cartilage fixing science you can read about here. Of course, we just had to get on the mics to record a podcast for you, and in addition to talking all things cutting-edge joint therapy, peptides, and regenerative medicine, we also delved into what I consider to be one of the most important discussions I've ever had on my show—particularly related to worldwide health, Covid, vaccinations, long-haul Covid syndrome, and perhaps the most important consideration of all: whether or not I personally plan to get vaccinated (I think you'll be quite surprised at the ultimate outcome of the discussion, which begins about the 38:00 mark). He is President and Founder of BioReset™️ Medical and Medical Advisor of BioReset Network. He is a board-certified anesthesiologist with over 20 years of experience in practicing medicine, focusing the last 14 years on functional and regenerative medicine. He graduated from the University of Washington School of Medicine and completed his residency in anesthesiology at the University of California San Francisco (UCSF), and has completed a fellowship in functional medicine. Dr. Matthew Cook's early career as an anesthesiologist and medical director of an outpatient surgery center that specialized in sports medicine and orthopedic procedures provided invaluable training in the skills that are needed to become a leader in the emerging field of regenerative medicine. His practice, BioReset™️ Medical, provides treatments for conditions ranging from pain and complex illness to anti-aging and wellness. He treats some of the most challenging to diagnose and difficult to live with ailments that people suffer from today, including Lyme disease, chronic pain, PTSD, and mycotoxin illness. Dr. Cook's approach is to use the most non-invasive, natural, and integrative treatments possible. In this discussion with Dr. Matthew Cook, you'll discover: -The circumstances that brought Ben to Matt's office most recently...09:20 -Why Ben's knee got worse and not better with all the treatment it received...16:50 -A new protocol that allows joint healing without invasive surgery...21:00 -Dr. Matthew Cook and his take on Covid and vaccines...38:05 -Concerns with toxins and microplastics in the vaccines...45:00 -Dr. Matthew Cook and his thoughts on alternative, non-vaccine treatments for Covid and the vaccine...49:45 -How effective are peptides at preventing or treating Covid...56:40 -What are the best vaccination options available?...1:00:45 -Should someone who has had Covid be a pariah in society if they aren't vaccinated?...1:12:15 -Ben's thoughts on vaccines after this discussion with Dr. Matthew Cook...1:15:25 -Will Ben Greenfield get the Covid vaccine, or will he not?...1:19:40 -And much more! Upcoming Events: Join me and my wife Jessa at Runga for The Gathering. Click here to grab one of the very limited spots we have open to the public for The Gathering at Runga (October 7-9, 2021). Las Vegas Keto Expo (October 15-16, 2021). Ben will be speaking at the Las Vegas Keto Expo along with 13 other keto experts. The first 300 guests to register here will get a free drink chip for the poolside party and a free t-shirt. Keep up on Ben's LIVE appearances by following bengreenfieldfitness.com/calendar Episode sponsors: -Kion Aminos: Building blocks for muscle recovery, reduced cravings, better cognition, immunity, and more. -JOOVV: After using the Joovv for close to 2 years, it's the only light therapy device I'd ever recommend. Give it a try: you won't be disappointed. For a limited time, Joovv wants to hook you up with an exclusive discount on your first order. Just apply code BEN to your qualifying order. -Butcher Box: Delivers healthy 100% grass-fed and finished beef, free-range organic chicken, and heritage breed pork directly to your door on a monthly basis. All their products are humanely raised and NEVER given antibiotics or hormones. -Organifi Green Juice: Now you can get all your healthy superfoods in one glass...with No Shopping, No Blending, No Juicing, and No Cleanup. Get a 20% discount on your entire order when you use discount code BENG20. https://bengreenfieldfitness.com/cook

In this best of episode, Dr. Lynda Frassetto, a nephrologist and professor emeritus in the department of medicine at University of California San Francisco (UCSF), shares important information about how acid in your diet affects your kidney health and longevity.

In this episode, I converse with Prof. Prachee Avasthi, an Associate Professor of Biochemistry and Cell Biology at the Geisel School of Medicine at Dartmouth College. She completed a PhD in neuroscience under the supervision of Wolfgang Baehr at the University of Utah and a Postdoc with Wallace Marshall at the University of California San Francisco (UCSF). Prachee started her own research group at the University of Kansas Medical Center before moving to Dartmouth in 2020 and she also serves on the Board of Directors of eLife and is the incumbent President of ASAPbio (Accelerating Science and Publication in biology), a non-profit initiative promoting innovation and transparency via preprints and open peer review. Prachee's group uses the unicellular green alga Chlamydomonas reinhardtii to study the formation of the cellular antenna, the cilium, and how its assembly is coordinated with other cellular processes. We indulge in a terrific conversation on her phenomenal journey through science and life; being exposed to research as an undergrad and graduate school in neuroscience; wonderful mentors who have inspired her and making mistakes by the plenty; the fun and collaborative aspects of science; the importance of fundamental research; actively reforming science and scientific publication through preprints and fixing the broken pipeline; communicating science through Twitter and stitching unexpectedly remarkable collaborations; and many more things!!

Dr. Rony Francois is a fourth-year resident at the University of Florida. He is currently working through a research elective at the University of California San Francisco (UCSF) and will be heading back to UCSF as a dermatopathology fellow soon. Dr. Francois has several research interests, but his primary focus is melanoma. Get to know more about Dr. Francois's research and his love of "spontaneous" travel.

Dr. Rony Francois is a fourth-year resident at the University of Florida.  He is currently working through a research elective at the University of California San Francisco (UCSF) and will be heading back to UCSF as a dermatopathology fellow soon. Dr. Francois has several research interests, but his primary focus is melanoma. Get to know more about Dr. Francois's research and his love of "spontaneous" travel.

Dr. Ramana (Ramo) Naidu is an anesthesiologist and pain physician who is the medical director of pain management at MarinHealth Medical Center and the medical director of Marin Specialty Surgery Center. He helps patients manage, reduce, or eliminate pain and suffering that occurs after medical illness, trauma, or surgery and puts an emphasis on preventing pain from becoming persistent. Naidu is primarily based at California Orthopedics & Spine, serving to help patients with pain before and after surgery. He emphasizes trying to manage pain without relying on opioid medications using a multi-disciplinary approach involving pain psychologists, physical therapists, complementary and integrative approaches. He performs advanced interventional procedures with the goal of sustained relief. Beyond epidural, joint, sympathetic and peripheral nerve injections, Naidu performs radiofrequency ablation of major joints and nerves and minimally-invasive spine procedures such as indirect and direct lumbar decompression, posterior sacroiliac joint fusion, and intradiscal therapeutics. As a neuromodulator, he is an expert on spinal cord stimulation (SCS), dorsal root ganglion stimulation (DRGS), and peripheral nerve stimulation (PNS). Naidu earned a medical degree at the University of Wisconsin School of Medicine and Public Health in Madison where he was born and raised. He completed a residency in anesthesiology at the University of Washington in Seattle, followed by a fellowship in pain management at University of California – San Francisco (UCSF) where he continued to practice for another five years as an assistant professor. He was a Fulbright Scholar in public health in Copenhagen, Denmark, with the World Health Organization (WHO) Regional Office for Europe. During this time, he studied hospital-acquired infections and the dissemination of information regarding prevention. Dr. Naidu is engaged in clinical research as he is interested in ensuring that we have safe, economical, and effective therapies for specific pain conditions. For any questions about which studies and therapies he is involved with, please enquire. The professional societies Naidu belongs to include the American Society of Anesthesiologists, California Society of Anesthesiologists, American Society of Regional Anesthesia and Pain Medicine, International Association for the Study of Pain, American Society of Interventional Pain Physicians, California Society of Interventional Pain Physicians, North American Neuromodulation Society, International Neuromodulation Society, American Society of Pain and Neuroscience, and is the President-Elect of the Pacific Spine & Pain Society. dr.ramonaidu on IG; Ramo Naidu MD on LinkedIn ramonaidu@me.com This podcast is powered by Pinecast.

Hello and Welcome to the Urology COViD Lecture Series Podcast! Brought to you by the UCSF Department of Urology. In today's episode, we have Dr. Benjamin Breyer from the University of California San Francisco (UCSF) talking about Radiation Induced Complications of the Lower Urinary Tract. Learn more by visiting our website! urologycovid.ucsf.edu.

This is part 2 of our conversation with Dr. Sosa. Our gest is Dr. Julie Ann Sosa, MD, MA, FACS, professor and chair of the Department of Surgery and holds the Leon Goldman, MD, Distinguished Professorship in Surgery at the University of California San Francisco (UCSF). Dr. Sosa received her Bachelor of Arts degree at Princeton University. From there, she went to Oxford University where she received her Master of Arts degree. After that, Dr. Sosa went to Johns Hopkins University where she received her MD, and then did the Halsted residency program, followed by a fellowship. In this podcast you’ll hear about Dr. Sosa’s thoughts on diversity in medicine, her advice to people aspiring to be a doctor, and her view on what may happen in the medical industry in 10 years and what makes medicine the greatest profession in the world. White Coat Story is a podcast series for school students to gain first-person insights into the practice of medicine, and what it takes to get there.

Big day today with the approval of Ga68-PSMA PET/CT by the US Food and Drugs Administration (FDA). The FDA have approved a combined academic application from the University of California San Francisco (UCSF) and the University of California Los Angeles (UCLA), and means that those two centres now have FDA approval to use PSMA PET/CT for staging newly-diagnosed prostate cancer, as well as those with suspected recurrence following previous treatment. Today we chat with the UCSF team behind the application, led by Dr Thomas Hope, Nuclear Medicine Physician and Radiologist, and his urology colleagues Dr Peter Carroll and Dr Matt Cooperberg. Fantastic discussion about what this means for access to PSMA PET/CT across the whole country; what it means for trial design; what other agents are on the horizon; and a steal peak from Dr Carroll about other research areas in PSMA he is exploring at UCSF. Regular hosts Professor Declan Murphy and Dr Renu Eapen are joined once again by Professor Michael Hofman, Nuclear Medicine Physician at Peter MacCallum Cancer Centre. LinksFDA news release on PSMA PET/CT UCSF UrologyUCSF Nuclear MedicineUCLA UrologyUCLA Nuclear Medicine

Our guest is Dr. Julie Ann Sosa, MD, MA, FACS, professor and chair of the Department of Surgery and holds the Leon Goldman, MD, Distinguished Professorship in Surgery at the University of California San Francisco (UCSF). Dr. Sosa received her Bachelor of Arts degree at Princeton University. From there, she went to Oxford University where she received her Master of Arts degree. After that, Dr. Sosa went to Johns Hopkins University where she received her MD, and then did the Halsted residency program, followed by a fellowship. In this podcast, you’ll hear about what an average day is like for a chair of surgery, her scenic path to becoming a surgeon, and the impact her father had on her journey there. White Coat Story is a podcast series for school students to gain first-person insights into the practice of medicine, and what it takes to get there.

Un equipo internacional de 200 científicos coordinado por el PhD Nevan Krogan, de la Universidad de California San Francisco, identificó las vulnerabilidades comunes de los últimos tres coronavirus mortales, incluyendo el de la actual pandemia, el SARS CoV 2. Conocer el punto débil y los mecanismos de interacción de estos temibles virus puede ayudar a combatirlos mejor y también estar preparados para futuras pandemias con otros coronavirus. RFI pudo conversar con uno de los “corresponding authors” principales. Hasta no hace mucho, los coronavirus en humanos provocaban resfriados o gripes no muy graves, pero desde hace veinte años han aparecido tres coronavirus letales, entre ellos el Sars CoV 2, de la actual pandemia. Pero, ¿si se pudiera conocer el punto débil o el talón de Aquiles de estos tres últimos coronavirus? Es lo que ha buscado un equipo internacional de 14 instituciones de renombre, incluido el Instituto Pasteur de Francia y que abarca a 200 científicos de distintas especialidades. El coordinador general fue Nevan Krogan, PhD, director del Instituto de Biociencias Cuantitativas (QBI) de la Universidad de California San Francisco (UCSF) y los resultados fueron publicados en la revista Science. El estudio incluyó el análisis de 740 mil registros médicos de pacientes infectados con el nuevo coronavirus. También se estudió qué drogas inhiben los mecanismos de estos tres coronavirus y se hizo un mapa de las interacciones que existen entre las proteínas de los virus y las proteínas de las células huésped humanas. Conocer las similitudes de estos tres coronavirus, el Sars Cov 1 del 2002, el Mers CoV del 2012 y el actual, el Sars Cov 2, ayuda a concebir futuros tratamientos para combatir la actual pandemia e incluso otras que puedan aparecer en el futuro. Aprovechando un mapa de proteínas o “interactoma” del Sars CoV2 (llevado a cabo en abril del 2020 y publicado en la revista Nature y Cell ) que registra cómo las proteínas de este virus interactúan con las proteínas de la célula huésped humana, los investigadores lograron esta vez construir los mapas de los tres coronavirus letales, destacando los mecanismos comunes que tienen. RFI conversó con el investigador en virología Adolfo García Sastre, profesor del departamento de microbiología de la prestigiosa Escuela de Medicina de Monte Sinaí en Nueva York, en pleno corazón de Manhattan. García Sastre es uno de los autores correspondientes, corresponding author, de esta vasta investigación. Las investigaciones en laboratorio llevadas a cabo por el equipo de Adolfo García Sastre se centran en los inhibidores, experimentando con diferentes drogas ya existentes, entre ellas, el remdesivir. Así también RFI  entrevistó al bioquímico Iñigo Barrio Hernández, él trabaja con el equipo de Pedro Beltrao, del Instituto Europeo de Bioinformática  en Hinxton, cerca de Cambridge, en el Reino Unido, una filial del EMBL, Laboratorio Europeo de Biología Molecular. Escuche aquí el programa en su versión larga con los dos especialistas: Esta investigación, es sobre todo la suma de muchos esfuerzos en el mundo científico y son varios aspectos que se tratan. Entrevistados: El virólogo Adolfo García Sastre del departamento de Microbiología, de la Icahn School of Medicine at Mount Sinai, Nueva York e Iñigo Barrio Hernández del Instituto Europeo de bioinformática del EMBL, European Molecular Biology Laboratory (EMBL-EBI), Hinxton, Reino Unido.            

¿Quieres saber cómo funciona el cerebro y cómo se conecta con nuestro corazón?  Este capítulo de D’mente Positivo formó parte de una de nuestras maravillosas clases magistrales para nuestro Círculo de Influencia, y contó con la presencia de uno de los neurocientíficos más importantes de todo el mundo, el Dr. Facundo Manes, quien estuvo compartiendo con nosotros acerca de la importancia del desarrollo de las habilidades blandas, y los procesos de aprendizaje del cerebro. Uno de los puntos más apasionantes de este encuentro, fue la explicación detallada que nos dio Facundo sobre la necesidad humana de estar en constante contacto social, además del énfasis que hizo en que: Siempre debemos mantenernos aprendiendo cosas nuevas, sin importar nuestra edad. Sobrevivir y pertenecer es más importante que la verdad. El antídoto contra el miedo es la cooperación. Biografía de Facundo Manes El Dr. Manes se graduó de médico en la Facultad de Medicina de la Universidad de Buenos Aires (UBA), PhD in Sciences, Cambridge University, Inglaterra. Presidente de la Fundación INECO para la investigación en neurociencias y del Instituto de Neurociencias de la Fundación Favaloro. Argentina. Profesor Visitante en el Departamento de Neurología de la Universidad de California San Francisco (UCSF, EEUU) y Profesor en la Universidad de South Carolina (EEUU) y de la Universidad Macquarie (Sydney, Australia). Learn more about your ad-choices at https://news.iheart.com/podcast-advertisers

Dr. Erika Moseson, founder of Air Health Our Health, discusses the impact of medicine on the economy, social justice issues, and public health. [01:17] Why Dr. Moseson Chose Pulmonary & Critical Care [03:33] Tips for Students Who Are Interested in Pulmonary & Critical Care [06:39] How Forest Fires and COVID-19 Have Impacted Dr. Moseson [10:28] Pulmonary Health & the Economy [12:50] Advocacy as a Medical Student [19:40] Dr. Moseson’s Words of Wisdom for Medical Students & Pre-Meds Erkeda DeRouen chats with Dr. Erika Moseson, a pulmonary and critical care doctor based in Portland, Oregon. Dr. Moseson is the Founder of Air Health Our Health, a company which is invested in promoting healthy air and fighting climate change. Why Pulmonary & Critical Care? Dr. Moseson liked aspects of both procedural and non-procedural medicine — which is why she found it difficult to choose a specialty. She completed her residency in internal medicine at the University of California San Francisco (UCSF) where she did a rotation in pulmonary & critical care. She enjoyed this specialty as it connected to the real world in terms of public health but also to more intense medicine in the ICU. Tips for Students Who Are Interested in Pulmonary & Critical Care Dr. Moseson encourages students who are interested in pulmonary and critical care to research and apply for residency programs that offer this specialty, and that have faculty in this specialty. They should do research into the aspects of this field that interest them, and how this matches with a given residency program. Pulmonary Health & the Economy Physicians should work to “make what is invisible visible.” Issues like forest fires are widely visible, and people can see that it is bad for our lungs. However, issues like terrible air quality in certain areas often go unnoticed. Air pollution — particulate matter — has been shown to cause respiratory issues like heart attacks, asthma, strokes, COPD, and more. Therefore, physicians should help to educate the public. Air quality issues often affect the poorest people the most. For example, a house offers a layer of protection from bad air quality. Therefore, the homeless might be affected two to three times more than a housed person in the same area if there is poor air quality. Furthermore, it is no coincidence that poor air quality itself often occurs in areas inhabited by minority groups. Even if the public is not concerned about the health of affected populations, we can use the economic costs of healthcare to convince them. It is more economically beneficial to have healthy people who earn money, rather than those who have to stay home sick and incur exorbitant costs for things like inhalers. Advocacy as a Medical Student Dr. Moseson sympathizes with students who struggle to participate in advocacy for projects about which they are passionate because they are afraid to offend or to step out of line. Nevertheless, Dr. Moseson encourages medical students to learn the science around the topic that is their passion. The students can be an educated voice of reason in their organizations, and provide a valuable scientific perspective on suggested ideas. She also encourages students to participate in research projects, which is not just important for their medical education, but can inform and enhance their advocacy as well. Check out Dr. Moseson’s Twitter, and Facebook. Also, check out the Air Health Our Health website.

COVID-19 has had an incredible impact on all of our lives. The pandemic has got us all thinking seriously about our physical and mental health and what it means to have immune strength, now and in the future, as well as what we can do to support our mental health. On today’s Broken Brain Podcast, our host Dhru talks to Dr. Matthew Cook, a board-certified anesthesiologist and the founder of BioReset Medical, located in Silicon Valley. He graduated from the University of Washington School of Medicine and completed his residency in anesthesiology at the University of California San Francisco (UCSF). He has been practicing medicine for over 20 years, focusing the last 14 years on Functional and Regenerative Medicine. Dr. Cook has extensive experience using cutting-edge treatment protocols that support and modulate the immune system and help one’s own body to prevent and combat viral illness. His practice, BioReset™ Medical, provides treatments for conditions ranging from pain and complex illness to anti-aging and wellness. At BioReset™ Medical, he treats some of the most challenging to diagnose and difficult to live with ailments that people suffer from today, including Lyme disease, chronic pain, PTSD, and mycotoxin illness. Dr. Cook’s approach is to use the most non-invasive, natural and integrative ways possible.In this episode, Dhru and Dr. Cook dive deep into the topic of COVID-19. They talk about hydroxychloroquine and Dr. Cook’s experience using it in his practice. They discuss peptides and how they can be used to support the immune system for chronic infections like mold, Lyme, as well as COVID-19. They also talk about ketamine and how Dr. Cook is using it to treat patients experiencing PTSD and post-COVID syndrome.In this episode, we dive into: -What you need to know about hydroxychloroquine and COVID-19 (7:03) -What Dr. Cook is doing to support his immune system (13:41) -Why ozone therapy can be helpful in treating coronavirus (22:07) -What makes you more susceptible to catching COVID-19 and experiencing complications (35:36) -How peptides can help regulate your immune system and treat COVID-19 (42:12)-What we need to know about a vaccine (51:05)-How COVID-19 impacts the brain (1:08:10)-Overcoming coronavirus and PTSD (1:13:39)-How ketamine can help with depression and PTSD (1:29:52) -Where to learn more about Dr. Matthew Cook (1:37:13)For more on Dr. Cook you can follow him on Instagram @bioresetmedical, on Facebook @bioresetmedical, on Twitter @bioresetmedical, and through his website https://www.bioresetmedical.com/.Also mentioned in this episode:-VirusReset Program - https://www.bioresetmedical.com/virusreset/-KetamineReset Program - https://www.bioresetmedical.com/ketaminereset/-BioReset Podcast - https://bioresetpodcast.com/For more on Dhru Purohit, be sure to follow him on Instagram @dhrupurohit, on Facebook @dhruxpurohit, on Twitter @dhrupurohit, and on YouTube @dhrupurohit. You can also text Dhru at (302) 200-5643 or click here https://my.community.com/dhrupurohit.Interested in joining Dhru’s Broken Brain Podcast Facebook Community? Submit your request to join here: https://www.facebook.com/groups/2819627591487473/. See acast.com/privacy for privacy and opt-out information.

Dr. Matthew Cook, MD is a board-certified anesthesiologist with over 20 years of experience in practicing medicine. He graduated from the University of Washington School of Medicine and completed his residency in anesthesiology at the University of California San Francisco (UCSF). Currently, he is the Founder of BioReset Medical, located in Silicon Valley.  Dr. Cook has extensive experience using cutting-edge treatment protocols that support and modulate the immune system and help one’s own body to prevent and combat viral illness. Relative to the current pandemic, he has spent the past many weeks distilling the latest research, talking with experts around the world and integrating his vast clinical experience to provide up-to-date information to the public and medical practitioners. Learn more about Dr. Cook here

Learn about the seven-year integrated plastic surgery residency program at the University of California - San Francisco (UCSF), with with Dr. Debbie Martins. Recorded in June 2020.

Cutting edge research coming out of University of California San Francisco (UCSF) in the antiviral field. Are Kinase Inhibitors the magic bullet to kill the Coronavirus ? --- Send in a voice message: https://anchor.fm/james-herlihy/message

Breast cancer is preventable and yet, many women all over the world still get it. The question now is, how can you prevent and reduce your risks of developing breast cancer? Laura Esserman, MD is determined to change things through the WISDOM (Women Informed to Screen Depending on Measures of Risk) study.  Laura Esserman, MD is a Professor of Surgery and Radiology at the University of California San Francisco (UCSF), and she is also the Director of the UCSF Breast Care Clinic. Her work in breast cancer spans the spectrum from basic science to public policy issues and the impact of both on the delivery of clinical care.  Dr. Esserman is recognized as a thought leader in cancer screening and overdiagnosis, as well as innovative clinical trial design. She led the creation of the University of California-wide Athena Breast Health Network, a learning system designed to integrate clinical care and research as it follows 150,000 women from screening through treatment and outcomes.  The Athena Network launched the PCORI-funded WISDOM (Women Informed to Screen Depending on Measures of Risk) study, which tests a personalized approach to breast cancer screening in 100,000 women. Dr. Esserman is also a leader of the innovative I-SPY trial model designed to accelerate the identification and approval of effective new agents for women with high-risk breast cancer. Dr. Esserman earned her MD and MBA from Stanford University, and her Bachelor's in the History of Science from Harvard University. What You’ll Hear On This Episode of When Science Speaks Laura Esserman, MD talks about her work in personalized medicine  Why personalized medicine is crucial for breast cancer treatment What is the WISDOM (Women Informed to Screen Depending on Measures of Risk) study and what does it hope to accomplish? Dr. Esserman talks about the current protocol for mammograms and why the approach needs to change The challenges that the WISDOM study has faced so far How Dr. Esserman and her team have been communicating the value of the WISDOM trial and how they encourage women to enroll in the study What are the implications of personalized medicine from the patient, government, and public health standpoint? The lessons that Dr. Esserman has learned in the process of putting together a coalition for successful trials Connect with Laura Esserman, MD Laura Esserman, MD on LinkedIn  WISDOM Study  The importance of personalized medicine Laura Esserman, MD has built her career around trying to deliver optimal care to everyone, and this includes designing care based on biology, patient preference, and clinical performance. Personalized care revolves around the recognition of the different risk factors for every person and acknowledging the fact that the treatment procedure for diseases varies from person to person. It allows patients to get the care they need based on their own profile, reducing the risks of overtreatment. She is particularly interested in diagnosing and identifying the various risk levels of breast cancer in diagnosed patients, thereby giving them the help they need to feel better and get better. This is the reason why Dr. Esserman’s work with the WISDOM study is focused on how to right-size breast cancer treatment. She says that there is a wealth of study around breast cancer and treatment options for those who need it and being able to zero-in on the right treatment plan for a patient risk level is crucial to optimal and efficient health care. The WISDOM (Women Informed to Screen Depending on Measures of Risk) study and its impact on breast cancer diagnosis and treatment The screening process for breast cancer has pretty much remained the same over the past four decades. Initially, breast cancer was considered a single disease and it was noticed by doctors that late diagnosis often had worse outcomes than those who were diagnosed early. Though screening has been helpful, it hasn’t had the kind of impact that medical professionals were hoping for which is why Dr. Esserman is intent on making the process for diagnosis and treatment better. The PCORI-funded WISDOM study intends to address this issue and it has zeroed-in on two things: proper screening of how malignant or how advanced the cancer is, and determining which type of breast cancer the patient has. This shifts the idea of treatment from being a uniform approach to a more personalized treatment plan. By retrofitting the process of diagnosis and treatment, WISDOM is able to properly address the needs of women with breast cancer. Learn more about Laura Esserman, MD and the WISDOM study on this episode of When Science Speaks.  Connect With Mark and When Science Speaks http://WhenScienceSpeaks.com https://bayerstrategic.com/ On Twitter: https://twitter.com/BayerStrategic On Facebook: https://www.facebook.com/Bayer-Strategic-Consulting-206102993131329 On YouTube: http://bit.ly/BSConTV On LinkedIn: https://www.linkedin.com/in/markdanielbayer/ On Instagram: https://www.instagram.com/bayerstrategic/ On Medium: https://medium.com/@markbayer17 Subscribe to When Science Speaks on Apple Podcasts or Stitcher

Hi again & welcome to the series on Emotional Intelligence.As I was putting together the outline of all the areas of focus for this series, it became obvious that before going into self-awareness, self-confidence and all other aspects of ‘self’, it would be valuable to dive into what is ‘self’ in it’s own right. To have self understood first before going further was my goal with this episode.Thanks for John McCarthy, head of Applied Psychology at UCC, I was connected with Dr. Zelda Di Blasi, and we recently recorded this one over zoom, all about ‘Self’.About Dr. Di BlasiDr Zelda Di Blasi, MPsychSc, PhD, CPsychol (BPS) is co-director of the MA in Positive & Coaching Psychology. After completing her Masters in Health Psychology at University College Galway, founded by the Medical Research Council, Zelda completed her PhD/DPhil in Health Sciences at the University of York on the placebo effect and health care interactions.Her interest in Positive Psychology evolved during her Post-Doctorate in Integrative Medicine and Health Psychology, when Zelda worked with Professor Susan Folkman at the University of California San Francisco (UCSF). A that time, she received a Teaching Fellowship  from UCSF and San Francisco State University.In 2006 Zelda took up her appointment as lecturer in the School of Applied Psychology in UCC, and later set up a Masters programme in Positive & Coaching Psychology, which she currently co-directs.Zelda has diplomas in Contemporary Yoga and Modern Dance, and an Advanced Diploma in Personal, Leadership and Executive Coaching accredited by the ICF and the EMCC. She is a certified Health & Wellness Coach with the Institute of Health Sciences, a HeartMath Coach/Mentor, and a Strengths Provider with CAPP (Centre of Applied Positive Psychology).  --During this interview we discussed: Zelda’s background in Psychology and teachingDoing her PhD on the placebo effectHow she discovered her interest for Psychology at the age of 18 and falling in love with the areaZelda’s interest and passion for learning including Yoga, Mindfulness and Modern Dance and how this all connects in with the Mind, Body and SpiritWhat is ‘the self’ and how does it develop?Finding the answer to the question ‘who am I?’How does ‘the self’ influence how we thinkWhen is it formed?Breaking down the self – what is it made up of?The mirror test with a baby to show a sense of self has developedWhy we use it so naturally without thought?Identity v Self – crossovers and comparisonsSelf is more at the marco levelHistory of the self?William James the first professor of psychologySchools of Thought on it?The role of Ego and how it compares to Self?Value of Self-esteem, compassion and empathyEmphasis on self-compassion more than self-esteemThe Self and spiritualityIs Self an Illusion? Or is it real?Ted Talks worth checking out on SelfChristine Neff - The space between self-compassion and self-esteemDaniel Gilbert – Talk on Happiness – affective forecastingBiases that exist on selfthe illusion of transparency – eg presenting and anxious about this – we are over estimating what others see in usthe spotlight effect – eg you feel like you’re on stage and with a spotlight on you – but the fact is people aren’t looking at you in that way – the cool v nerdy t-shirt exampleAffective forecasting – what you think will make you happy or unhappy – turns out we are not very goodDurability bias – how will you feel if you get a promotion at work? How long will this feeling last? Not that long….for some more than othersJust being aware of these biases helps and focusing on the present!How to get a better sense of self in the world we live in now?Tools that you can use to better understand SelfThe Best Possible Self?4 days visualizing what this looks like for you10 mins a dayDo it in a real relaxed spaceConnect with the feelingWhat comes up and what the image is?What your dream or ideal self looks like?Then devise the steps to take to get there!Visualization tools & Vision boardsTaking one small step at a timeThe value of journaling each day helps to learn more about self6 minute journalMorning pages (30mins)The home retreat you have now!Random acts of kindnessWhat Zelda is working on now – the Book on Pleasure!How to Connect in with Zelda – email: diblasi@ucc.ieIf you’re interested in more details on what was covered in this episode, would like to explore your own Emotional Intelligence deeper, I’d be happy to discuss this further and look at coaching opportunities.Please do get in touch via email at Rob@robofthegreen.ie or connect in over any of the social channels - @robofthegreen

Hi again & welcome to the series on Emotional Intelligence.As I was putting together the outline of all the areas of focus for this series, it became obvious that before going into self-awareness, self-confidence and all other aspects of ‘self’, it would be valuable to dive into what is ‘self’ in it’s own right. To have self understood first before going further was my goal with this episode.Thanks for John McCarthy, head of Applied Psychology at UCC, I was connected with Dr. Zelda Di Blasi, and we recently recorded this one over zoom, all about ‘Self’.About Dr. Di BlasiDr Zelda Di Blasi, MPsychSc, PhD, CPsychol (BPS) is co-director of the MA in Positive & Coaching Psychology. After completing her Masters in Health Psychology at University College Galway, founded by the Medical Research Council, Zelda completed her PhD/DPhil in Health Sciences at the University of York on the placebo effect and health care interactions.Her interest in Positive Psychology evolved during her Post-Doctorate in Integrative Medicine and Health Psychology, when Zelda worked with Professor Susan Folkman at the University of California San Francisco (UCSF). A that time, she received a Teaching Fellowship  from UCSF and San Francisco State University.In 2006 Zelda took up her appointment as lecturer in the School of Applied Psychology in UCC, and later set up a Masters programme in Positive & Coaching Psychology, which she currently co-directs.Zelda has diplomas in Contemporary Yoga and Modern Dance, and an Advanced Diploma in Personal, Leadership and Executive Coaching accredited by the ICF and the EMCC. She is a certified Health & Wellness Coach with the Institute of Health Sciences, a HeartMath Coach/Mentor, and a Strengths Provider with CAPP (Centre of Applied Positive Psychology).  --During this interview we discussed: Zelda’s background in Psychology and teachingDoing her PhD on the placebo effectHow she discovered her interest for Psychology at the age of 18 and falling in love with the areaZelda’s interest and passion for learning including Yoga, Mindfulness and Modern Dance and how this all connects in with the Mind, Body and SpiritWhat is ‘the self’ and how does it develop?Finding the answer to the question ‘who am I?’How does ‘the self’ influence how we thinkWhen is it formed?Breaking down the self – what is it made up of?The mirror test with a baby to show a sense of self has developedWhy we use it so naturally without thought?Identity v Self – crossovers and comparisonsSelf is more at the marco levelHistory of the self?William James the first professor of psychologySchools of Thought on it?The role of Ego and how it compares to Self?Value of Self-esteem, compassion and empathyEmphasis on self-compassion more than self-esteemThe Self and spiritualityIs Self an Illusion? Or is it real?Ted Talks worth checking out on SelfChristine Neff - The space between self-compassion and self-esteemDaniel Gilbert – Talk on Happiness – affective forecastingBiases that exist on selfthe illusion of transparency – eg presenting and anxious about this – we are over estimating what others see in usthe spotlight effect – eg you feel like you’re on stage and with a spotlight on you – but the fact is people aren’t looking at you in that way – the cool v nerdy t-shirt exampleAffective forecasting – what you think will make you happy or unhappy – turns out we are not very goodDurability bias – how will you feel if you get a promotion at work? How long will this feeling last? Not that long….for some more than othersJust being aware of these biases helps and focusing on the present!How to get a better sense of self in the world we live in now?Tools that you can use to better understand SelfThe Best Possible Self?4 days visualizing what this looks like for you10 mins a dayDo it in a real relaxed spaceConnect with the feelingWhat comes up and what the image is?What your dream or ideal self looks like?Then devise the steps to take to get there!Visualization tools & Vision boardsTaking one small step at a timeThe value of journaling each day helps to learn more about self6 minute journalMorning pages (30mins)The home retreat you have now!Random acts of kindnessWhat Zelda is working on now – the Book on Pleasure!How to Connect in with Zelda – email: diblasi@ucc.ieIf you’re interested in more details on what was covered in this episode, would like to explore your own Emotional Intelligence deeper, I’d be happy to discuss this further and look at coaching opportunities.Please do get in touch via email at Rob@robofthegreen.ie or connect in over any of the social channels - @robofthegreen

3D printing technology has the potential to impact almost every industry in the world — whether it's creating replacement parts for machines to quickly developing prototypes from scratch. Today, the impact 3D printing is having on the global fight against the coronavirus COVID-19 is significant. In this episode of our show, my colleague and fellow analyst Sarah Wallace and I take a look at the role 3D printing is playing — from rapidly creating protective face shields, respirator masks, nasal swabs and ventilator parts for use by front line workers and hospitals — to the challenges the industry faces, to spotlighting companies doing innovative things with 3D printing — and what's ahead.   What makes 3D printing such a great solution?   What makes 3D printing such a great solution? In a word: It's fast. With 3D printing, in the space of a short period of time (think hours not days or weeks) it's possible to design, prototype and produce an idea. And that? That incredibly rapid turnaround time is something that manufacturers can't (yet) do. Right now, supply chain issues and overwhelming demand are what is driving the need for 3D printing solutions. As a result, 3D printing is, and can continue to, have a big impact on the supply chain by filling short-term supply gaps that every industry is facing as we navigate the COVID-19 outbreak.   Here's but one example of how 3D printing can provide important solutions to the coronavirus COVID-19 pandemic and our supply chain problems —   Manufacturers of nasal swabs have been struggling to keep up with demand. These swabs are used for coronavirus tests and are very different from standard swabs, as they need to be long and skinny, made of synthetic fiber, and can't have a wooden shaft. While hospitals and communities want and desperately need to ramp up testing, this weak link in the supply chain is a big factor. That's where 3D printing can help. In a recent interview with CNN, HP's Raymond Pastor, acting president of 3D printing and digital manufacturing for HP indicated the company has the capacity to print 1 million swabs a week in the U.S. alone.     What are the limitations of 3D printing?   Sarah walked us through some challenges as it relates to 3D printing. For starters, not all 3D printed equipment is the same, and some is easier to produce than others. Equally as important, some 3D-printed equipment might be better than others, while some might not quite afford the level of protection that's needed. Some things require FDA approval to produce, and of course there's always the risk factor for companies producing these things that is inevitably important to consider.   Sarah also mentioned there's a skills gap that plays a role in the limitations and challenges of 3D printing, as well as some other things worth considering.   What companies in the 3D Printing Space Are Doing Some Really Innovative Things?   Our conversation in the webcast turned to the companies in the 3D printing space that are doing some really innovative things. Sarah is currently immersed in developing a 3D market insight report, so it wasn't hard to come up with examples of companies doing innovative things with 3D printing. This includes:   Siemens' Additive Manufacturing (AM) Network is an online order-to-delivery collaboration platform for the industrial additive manufacturing community and connects users, designers, and 3D print service providers to enable faster and simpler production of spare parts for machines like ventilators. Siemens is also making 3D printers available to the global medical community to speed design and production during the COVID-19 pandemic. Doctors, hospitals, and organizations in need of medical devices and designers and service providers can register for free access to the Siemens AM Network.   HP has developed a 3D printed hands-free door opener, a mask adjustor clasp that helps make masks more comfortable during long time wear, face shields, hospital grade FFP3 face masks that are reported to be available soon, and 3D printed parts for field ventilators are in development. HP and the company's partners are making validated design files for many parts that don't require complex assembly available for free. If you're a 3D designer or innovator (or know one) who wants to join the battle against COVID-19, you can contribute new applications and ideas to the collaborative effort directly from HP's website dedicated to 3D printing in support of COVID-19 containment efforts.   Dassault Systèms is using scientific simulation of the human sneeze to support the development of personal protective equipment (PPE) projects in the 3DEXPERIENCE Lab OPEN COVID-19 online community, as part of collaborative efforts to quickly answer unmet urgent needs during the COVID-19 pandemic. The simulations are used to demonstrate what happens when a person sneezes, to better understand the effectiveness of different PPE being developed and deployed, and to aid in improving their design. Dassault's simulator applications are already used in the aerospace and automotive industries to generate a dynamic simulation of fluid and air flow, and their simulation apps are likewise being used to help understand the flow physics of sneezes.   What are some 3D Printing Solutions Being Used in the Fight Against COVID-19?   Some of the big brands immersed in the 3D printing space — like Siemens, and HP, and Dassault we have heard of and might not be surprised by — but they are not alone. There are other companies in the 3D printing space that are also really stepping up.   Tangible Creative, MakerBot, Shapeways and other 3D printing companies in the NYC area have joined together to create the Covid Makers Response Coalition to help provide 3D printed supplies to area hospitals in need of gear. This group is printing 2,000 face shields a day for hospitals in the NYC area.   Voodoo Manufacturing, a NY-based 3D printing startup, has repurposed its 5,000 square-foot facility to mass produce emergency personal protective equipment for the healthcare workers and hospitals. It plans to print at least 2,500 face shields weekly. Hospitals and healthcare workers can place batch orders for protective face shields at CombatingCovid.com.   Carbon, a 3D printing firm is working with the University of California San Francisco (UCSF) to create nasal swabs.   SmileDirectClub is one of the largest 3D printing manufacturers in the US (who knew?) and is partnering with medial supply companies and healthcare orgs to produce supplies like face shields and respirator valves.   Protolabs, a Minnesota-based digital manufacturer, has prioritized medical orders on its manufacturing floor which includes ventilator parts and is also producing components for COVID-19 test kits   Formlabs, a Somerville, Mass-based developer and manufacturer of 3D printers and software is using 250 printers in its Ohio factor to manufacture 100,000 nasal swabs for COVID-19 testing every day.   Ford Motor Company and GE are partnering to expand production of ventilators and other critical equipment in the U.S. and currently using Ford's factories to produce plastic face shields and components for PPE, with a goal of assembling more than 100,000 face shields a week.   Volkswagon has formed a task force to adapt its manufacturing facilities much the way Ford and others have, and also plan on leveraging its more than 125 industrial 3D printers.   The allure of 3D printing is clear   As you'll see by our conversation here, the allure of 3D printing to combat coronavirus COVID-19 is clear. 3D printing solutions are affordable. They interject much needed rapid response capabilities into the manufacturing process and also augment gaps in the supply chain. The beauty and the strength of 3D printing lies in both the affordability of 3D printers and the network or the community of 3D printing enthusiasts. Just how big is that community of 3D printing enthusiasts?   According to a report published in August of 2019 by the Federation of American Scientists, there were some 600,000 purchases of 3D printers priced under $5,000 sold in the US alone in 2018, and some 140,000 industrial grade 3D printers sold worldwide. That means there are a lot of 3D printers out there. Even more impressive, to us anyway, is the knowledge base and expertise, and the strength of the community that's being created — both by gigantic companies in the 3D sector, as well as by smaller companies all over the world — is quickly becoming clear.   What role will 3D printing play as businesses begin to rethink and rework their business models post-pandemic? We predict that it will be a big one! Keep an eye out for Sarah's Market Insights Report on 3D Printing, which will be published in early May.

In this interview, Dr. Lynda Frassetto, a nephrologist and professor emeritus in the department of medicine at University of California San Francisco (UCSF), shares important information about how acid in your diet affects your kidney health and longevity.

Multiple sclerosis experts share advice on how to substantially improve your care when interacting with your neurologist. Key insights to develop trust and understanding with your doctor reviewed. Compelling info to help you advocate and communicate your goals and needs. Specific ways to make the most of your appointments addressed. Difficult questions are tackled such as progressive disease and long-term planning. Managing MS symptoms and wellness highlighted. Benefits of reviewing MRI images in the exam room outlined. Excellent tips on how to access free medication and MRI programs for people who are uninsured or have high out-of-pocket costs. Barry Singer MD, Director of The MS Center of Innovations in Care at Missouri Baptist Medical Center interviews: Flavia Nelson MD, Associate Professor of Neurology, Director Multiple Sclerosis Division at the University of Minnesota in Minneapolis. She completed her residency and multiple sclerosis fellowship at the University of Texas Health Science Center in Houston, Texas. Dr. Nelson has served as Chair of the Department of Defense Panel for Multiple Sclerosis Research Program, committee member on Consortium of MS Centers MRI Guidelines Committee and Chair of International Advisory Board on Brain Atrophy and MS (2016). Timothy West MD, MS Neurologist, Rocky Mountain Multiple Sclerosis Clinic in Salt Lake City, Utah. Dr. West completed medical school at the University of California-San Francisco (UCSF) and fulfilled his residency in neurology at UCSF. He has had extensive experience and research in the area of MS, including at the Cleveland Clinic Lou Ruvo Center for Brain Health in Nevada, the Sansum Clinic in California, and the UCSF MS Center in California. Visit: mslivingwell.org & ICanWithMS.org

Dr. Ida Sim is Professor of Medicine at the University of California San Francisco (UCSF), Director of Digital Health for the Division of General Internal Medicine, and codirector, Informatics and Research Innovation at UCSF’s Clinical and Translational Sciences Institute. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. I. Sim. Mobile Devices and Health. N Engl J Med 2019;381:956-968.

In this 102nd episode I welcome Dr. Dan Lowenstein to the show.  Dr. Lowenstein is a professor of Neurology and the Executive Vice Chancellor and Provost at University of California San Francisco (UCSF).  We discuss his lessons and advice for how to be successful professionally and personally. The Three Marriages book: http://www.davidwhyte.com/the-three-marriages/

076 | Regulations, Drug Discovery, and Collaborations Welcome to another episode of Biotechnology Focus radio. This week we’ll be discussing regulations when working with drugs, financing drug discoveries, and an East Coast collaboration that will develop new opportunities for marine biotechnology. I am your host, Michelle Currie, here to give you a run-down of the top stories of Canada’s biotech scene. +++++ Health Canada maintains tight control over the sale of drugs in Canada by applying the Food & Drug Regulations to all involved parties. In order to bring a drug product to market, a manufacturer must provide evidence to Health Canada on drug safety and efficacy, and demonstrate that processes planned for production are consistent with the regulations. Enforcement of the regulations is not limited to the pre-approval phase. After receiving approval, license holders must continue to ensure that all parts of their supply chain operate in compliance with Health Canada regulations. Logistic partners including importers, distributors and wholesalers are required to operate in compliance with the Good Manufacturing Practices (GMP) section of the regulations when working with drug products so that procedures in place do not adversely affect the quality of drugs. The GMP is broad in scope and covers numerous areas of responsibility such as building design, sanitation practices, distribution records/inventory control, record keeping and testing of products where necessary before they are made available for sale. One important aspect of GMP requirements is the stipulation that all procedures involving drug products are performed according to written procedures and are to be performed by qualified and trained personnel at all times. For some groups in the supply chain, this high level of accountability may not be achieved without significant updates to operational procedures or investments in additional staffing or equipment. The term “GMP” is recognized worldwide as the quality standard for drug products. However, how companies receive certification from their local regulatory bodies vary throughout the world. In some regions, GMP regulations have been enacted by a federal authority, but the actual approval of GMP compliance is not managed by that same authority, and instead, certification is provided by third-party auditors (for example the FDA in the United States). Health Canada has a unique system whereby evidence to demonstrate GMP compliance is approved directly by Health Canada before facilities are permitted to carry on activities with drug products. This pre-review system of GMP evidence may pose a barrier to entry for some groups looking to get into the drug product business, and is a frequent hurdle for importers wishing to bring drug products into Canada for further sale. Up until a few years ago, Health Canada’s efforts in GMP regulation and compliance were focused primarily on drugs in finished form. However, over time it became evident that regulating starting materials, otherwise known as active pharmaceutical ingredients (API) were also a crucial part of the process of ensuring the quality of finished drugs. Health Canada, therefore, made a significant update to the GMP regulations in 2013 by expanding their scope to include API sources. Given that a large proportion of API sources are located abroad, the recent adjustment to the GMP regulations has resulted in an increased regulatory burden for Canadian importers of drug products and manufacturers of drug products; particularly if they are sourcing API from numerous foreign facilities. Challenges for the drug supply chain with respect to GMP compliance may rise as the trend toward outsourcing and increased use of third-party distribution centres continues. It remains the responsibility of the drug product license holder to ensure that all locations involved in bringing their drugs to market in Canada are GMP compliant. Planning for GMP compliance at early-stages of negotiations with contractors can assist with minimizing delays and interruptions in supply chains and production of drug products in Canada. ++++++ CQDM (Quebec Consortium for Drug Discovery) and Brain Canada announce a $1 million nondilutive funding to AbCellera and the University of British Columbia. AbCellera will also be contributing $450,000 to the project, which will expand and apply its state-of-the-art microfluidic antibody discovery platform for the detection of function-modifying antibodies against G-protein-coupled receptor (GPCR) targets. The CQDM support was made possible by the financial contributions of five of its industrial members, including GSK, Janssen Pharmaceutical Companies of Johnson & Johnson, Merck, Pfizer, and Sanofi. These contributions underscore their commitment to driving innovation that can expand the accessible target space of antibody-based therapeutics, the fastest growing class of drugs. AbCellera, started in Carl Hansen’s laboratory at the University of British Columbia in 2012 has become a reputable name in antibody discovery from natural immune repertoires. AbCellera’s microfluidic singlecell screening platform allows for deep profiling of natural immune responses with an unmatched combination of throughput, speed, and assay capabilities. This funding will allow AbCellera’s to further expand its leading capabilities for antibody discovery against high-value complex membrane proteins that have proven intractable by conventional approaches, including hybridoma, phage and yeast display. The continued collaboration between AbCellera and the University of British Columbia is a model example of how public-private partnerships can efficiently translate cutting-edge research into practical applications to accelerate the discovery and development of new therapies for patients. Carl Hansen commented that, “AbCellera is now the recognized leader for antibody discovery against difficult membrane protein targets. To date, they have run successful discovery programs on six GPCR or ion channel targets. Their technology has vastly outperformed what is possible by classic hybridoma and display methods, has succeeded in generating hundreds of unique antibodies per target, and has provided leads to advance partner programs that were otherwise stalled.” This collaboration, will further expand AbCellera’s technology to enable direct cell-based assays capable of selecting ultra-rare antibodies with function-modifying properties. When combined with the throughput and speed of their platform, it will create game-changing capabilities for targeting complex membrane proteins.” ++++++ Thanks to a University of Toronto’s antibody engineering technology, a new cancer immunotherapy has received a US$62 million helping hand in its development. The therapy called, Myeloid Tuning, has been designed to boost the body’s anti-tumour immunity by removing cells that normally hinder or halt the immune system using engineered antibodies. They were developed at the University of Toronto’s Toronto Recombinant Antibody Centre (TRAC). Sidhu originally co-founded TRAC with Professor Jason Moffat as a state-of-the-art antibody engineering platform at the Donnelly Centre for Cellular and Biomolecular Research, where they are both coincidently faculty members. Engineered antibodies are becoming increasingly more popular, as their uses are more precise and will target any molecule or cell type for which they were designed. It is new therapy like these that are leading to a new generation of immunotherapy drugs. The research collaboration between Sidhu, Moffat and Max Krummel, a professor at the University of California San Francisco (UCSF), five years ago has led to myeloid tuning. In 2011, Krummel co-invented the first engineered immunotherapy against skin cancer. Three years later, Sidhu and Krummel cofounded Pionyr Immunotherapeutics in San Francisco to turn research ideas into something more concrete. Pionyr announced recently that it raised US$62 million from investors, bringing their total funding to $72 million. The funds have been raised over the course of two years to develop myeloid tuning into a form that will be compatible with humans. The funding boost came on the back of promising proprietary data obtained with antibodies created in Toronto. So far, Myeloid Tuning has been shown to be effective in multiple mouse tumour models. Starting from scratch in 2010, TRAC has grown immensely and become a sought-after platform with more than 50 ongoing collaborations worldwide. Moffat and Sidhu want to see a continual growth of new drugs developed in Toronto. Thanks to the support of philanthropist Terrence Donnelly, whose ongoing donations have founded the interdisciplinary biomedical research institute, Donnelly Centre, to support research and innovation. The most recent $10 million gift will be used to launch a new hub for biotechnology startups that will accelerate the translation of its research discoveries into new therapies. Its first occupants will be Systems Biologics Inc. and SciGenom Life Sciences, Canada, new Canadian corporations that will develop TRAC antibodies into treatments for cancer and other major diseases. +++++ Croda International acquires Nautilus Biosciences Canada Inc. The two companies already have a proven track record of successful collaborations during the past six years developing specific applications for skin care and hair care, as well as crop care. Croda intends to establish Nautilus as a Croda Centre of Innovation for Marine Biotechnology at the existing base at the University of Prince Edward Island. Through this acquisition and associated patents, Croda will utilise Nautilus’ innovative science for applications across all its market sectors. This location is ideal for biotechnology research and has already attracted and facilitated partnerships with many other biotechnology-based companies. Nautilus has exclusive global access to the Marine Microbial Library which is based at the University of Prince Edward Island. The founder of Nautilus, Russell Kerr explains that they have enjoyed a very positive and collaborative relationship with both Croda and the University of Prince Edward Island for a number of years and have always been impressed with Croda’s drive to develop the opportunities from marine biotechnology. Becoming part of the Croda group will provide Nautilus the resources and support to establish a key centre for the research and development of marine-derived natural products, as well as providing Croda new products for commercial success. Nautilus was founded in 2007 by professor Russell Kerr and, together with its world-class scientists, focuses on using marine microbial biodiversity to discover novel actives and materials. Roy Francis, executive director of the PEI BioAlliance adds, “Croda’s investment in Nautilus and Prince Edward Island is a great return on everyone’s commitment. It’s how a cluster works.” +++++ Well that wraps up another episode of Biotechnology Focus. For the full stories, please visit the website biotechnologyfocus.ca. Thanks again for listening! From my desk to yours – this is Michelle Currie.

Learn how to recognize facial skeletal abnormalities, and how to help patients help themselves.   Dr. Radhika Chigurupati is a board certified Oral and Maxillofacial Surgeon who specializes in orthognathic surgery for correction of developmental and acquired jaw and facial deformities. She sees both children and adults with jaw deformities, cleft and craniofacial anomalies, tooth eruption disturbances, jaw tumors and maxillofacial pathology, and sleep disorders/obstructive sleep apnea (OSA). She works with her colleagues in other medical and dental specialties to provide interdisciplinary care for these patients at Boston Medical Center (BMC), Beth Israel Deaconess Medical Center (BIDMC) and Franciscan Hospital for Children (FCFH). She has joined Boston University Henry M. Goldman School of Dental Medicine in March 2013 after spending 9 years at University of California San Francisco (UCSF) and one and half years at University of Maryland, Baltimore. During that time, she has practiced at UCSF Moffitt Medical Center, UCSF Benioff Children’s Hospital and University of Maryland Shock Trauma Center. Dr. Chigurupati completed her Oral and Maxillofacial Surgery training at University of Washington (UW), Seattle and subsequently a fellowship in Pediatric Maxillofacial Surgery at the Royal Children’s Hospital (RCH) in Melbourne, Australia. She has been an active member of the cleft and craniofacial teams at UW, UCSF and RCH.     Radhika Chigurupati, DMD, MS Associate Professor Oral and Maxillofacial Surgery 100 East Newton Street Suite 407 Boston, MA 02118 617-638-4386 Email: rchiguru@bu.edu