Podcasts about Mallinckrodt

Ben Beller, Partner at Sullivan & Cromwell LLP Ben Beller, Partner at Sullivan & Cromwell LLP, joins the podcast to walk through how companies can strategically navigate bankruptcy and restructuring during M&A. Drawing from experience on major cases like FTX and Silicon Valley Bank, Ben shares practical insights into Chapter 11 processes, planning strategies, liability management transactions, and how buyers can successfully acquire distressed assets. A must-listen  for corporate development professionals, acquirers, and M&A legal teams looking to build competency around distressed transactions. Things you will learn: The differences between Chapter 7, 11, and 13 bankruptcies and when to use each How liability management transactions work and their growing role in restructuring What buyers need to know about acquiring businesses in bankruptcy _______________ What is the Buyer-Led M&A™ Virtual Summit This isn't just another webinar—it's an interactive experience designed to give you the tools and strategies to lead your M&A deals with confidence. This half-day event brings together corporate development leaders and M&A experts to explore Buyer-Led M&A™, showing how you can take control of every stage of the deal. Register Now ________ This episode is sponsored by FirmRoom.  The World's Most Intuitive Virtual Data Room With AI Contract Analysis No Per-Page Fees. No B.S. Just Smarter, Faster Deals. Get started with your free trial today! ________ Episode Timestamps: [00:04:00] Ben Beller's background and major bankruptcy cases (FTX, SVB, Mallinckrodt) [00:07:30] Chapter 7 vs. Chapter 11 – key differences [00:11:30] Signs companies should begin planning for bankruptcy [00:14:00] Prepackaged vs. prearranged vs. freefall bankruptcies [00:17:30] Importance of lender relationships and communication [00:22:00] Role of private credit and debt trading in distressed situations [00:28:00] Liability management transactions explained: dropdowns, up tiers, and more [00:35:00] Trends in liability management and how they defer bankruptcy [00:41:00] M&A in bankruptcy: How buyers can seize opportunities [00:46:30] Understanding stalking horse bids and auction dynamics [00:54:30] Common mistakes in buying businesses out of bankruptcy [01:01:00] Bankruptcy reform trends and cost implications  

Good morning from Pharma and Biotech daily: the podcast that gives you only what's important to hear in Pharma and Biotech world.The Trump administration has withdrawn CDC nominee Dave Weldon at the last minute, while NIH and FDA picks advance. Acelyrin has implemented a poison pill strategy to prevent Tang Capital from acquiring the company. Johnson & Johnson and Legend Biotech are investing $150 million to increase Carvykti production. Mallinckrodt and Endo have announced a $6.7 billion merger. Wacker Biotech offers services for advanced therapies. Other news includes updates on Amgen's Uplizna, J&J's talc lawsuit, and Roche's obesity play.

Welcome, Med Tech Gurus! You are in for a fantastic episode today as we sit down with Samina Bari, a strategic advisor with over 30 years of experience in business strategy, corporate governance, and operations. Samina has navigated high-stakes environments, working on transformative acquisitions worth over $40 billion, including major deals like Medivation by Pfizer and Ikaria by Mallinckrodt. In this episode, Samina shares her expertise on managing corporate crises, including cybersecurity breaches, hostile takeovers, and the challenges of scaling companies in complex industries. She also discusses her passion for innovation in healthcare, her advocacy for women-led ventures, and the importance of maintaining a clear "North Star" in business. Get ready to learn from a true leader in risk management and strategic advising. This episode is packed with valuable insights for anyone in the medtech or biotech fields.

Hongkong vor fünf Jahren: Über eine Millionen Menschen haben auf den Straßen demonstriert – gegen eine engere Anbindung der Sonderverwaltungszone an die Volksrepublik China. Die Demonstrationen sind eskaliert, es gab Verletzte und viele Festnahmen. Nun – fünf Jahre später – ist es dort seltsam still geworden. Wie viel ist von den Gedanken des Protests noch übrig? Wie geht es Hongkong Chinesinnen und Chinesen heute? Und: Wie viel Freiheit steckt noch in Hongkong? Darum geht es diesmal im Weltspiegel Podcast. Host Fumiko Lipp spricht dazu mit ARD-Korrespondentin Marie von Mallinckrodt, die in Hongkong war und dort zur Demokratiebewegung recherchiert hat. Außerdem zu hören: Der Demokratie-Aktivist Finn Lau, der einer der Organisatoren der Proteste war und deshalb ins Ausland fliehen musste. ----- Moderation: Fumiko Lipp Redaktion: Nils Kopp, Stefan Jäntsch, Julia Schuster Redaktionsschluss: 26.09.24 ------ Unser Podcast-Tipp: https://1.ard.de/derRestistGeschichtecp Alle Folgen des Weltspiegel Podcast findet ihr hier: https://www.ardaudiothek.de/sendung/weltspiegel-podcast/61593768/

Hongkong vor fünf Jahren: Über eine Millionen Menschen haben auf den Straßen demonstriert – gegen eine engere Anbindung der Sonderverwaltungszone an die Volksrepublik China. Die Demonstrationen sind eskaliert, es gab Verletzte und viele Festnahmen. Nun – fünf Jahre später – ist es dort seltsam still geworden. Wie viel ist von den Gedanken des Protests noch übrig? Wie geht es Hongkong Chinesinnen und Chinesen heute? Und: Wie viel Freiheit steckt noch in Hongkong? Darum geht es diesmal im Weltspiegel Podcast. Host Fumiko Lipp spricht dazu mit ARD-Korrespondentin Marie von Mallinckrodt, die in Hongkong war und dort zur Demokratiebewegung recherchiert hat. Außerdem zu hören: Der Demokratie-Aktivist Finn Lau, der einer der Organisatoren der Proteste war und deshalb ins Ausland fliehen musste. ----- Moderation: Fumiko Lipp Redaktion: Nils Kopp, Stefan Jäntsch, Julia Schuster Redaktionsschluss: 26.09.24 ------ Unser Podcast-Tipp: https://1.ard.de/derRestistGeschichtecp Alle Folgen des Weltspiegel Podcast findet ihr hier: https://www.ardaudiothek.de/sendung/weltspiegel-podcast/61593768/

SVP operates as “one big virtual global office” built on three functional “pillars” — sourcing, dealmaking and its operating partners — according to HJ Woltery, the firm's co-head of the European investment team. Bloomberg Intelligence's Noel Hebert and Phil Brendel had an in-depth feature interview with Woltery on European distressed debt. They delved into SVP's investment approach and how the restructuring landscape varies from the US and among European countries (7:15). Prior to that, Hebert and Brendel discussed August's telecom-led credit rally and what the start of rate cuts means for the corporate credit cycle. The podcast concludes with BI's Negisa Balluku joining the two for a roundtable discussion covering Avon, Hertz's make-whole decision, Gol airlines, TPG, Diamond Sports, Mallinckrodt, Yellow Corp. and the proliferation of cooperation agreements (1:02:25).

US Supreme Court Justice Brett M Kavanaugh would have a “great career as a restructuring professional,” according to University of North Carolina at Chapel Hill law professor Melissa B. Jacoby, as his Purdue Pharma 54-page dissent mirrored many bankruptcy lawyers' skepticism regarding the US trustee's arguments. In this episode of Bloomberg Intelligence's State of Distressed Debt podcast, part of the FICC Focus series, BI bankruptcy litigation analyst Negisa Balluku interviews Jacoby, author of the new book Unjust Debts, on the impact of the Supreme Court's Purdue decision on mass tort bankruptcies, including lingering questions about the future significance of consensual third-party releases (6:45). Earlier in the podcast, BI's Phil Brendel and Noel Hebert discuss how the corporate credit market appears immune to geopolitical risks that don't alter rate expectations. This episode concludes with all three discussing the latest developments in bankruptcy courts and distressed situations, including Incora, Gol Airlines, Mallinckrodt and Diamond Sports (50:15).

Send us a Text Message.Cary Claiborne is CEO of Adial Pharmaceuticals ( https://www.adial.com/ ), a clinical-stage biopharma company focused on developing therapies for the treatment of addiction and related diseases, specifically Alcohol Use Disorder (AUD). In the U.S. alone, an estimated 35 million people suffer from AUD, resulting in significant health, social and financial costs. Current treatment options present significant barriers to patient adoption, including abstinence and side effects, which can lead to social stigmatization.Mr. Claiborne has over three decades of experience in leadership roles with clinical and commercial stage, publicly traded biopharmaceutical companies. Most recently, Mr. Claiborne served as Chief Financial Officer and director of Indivior PLC, a publicly traded specialty pharmaceutical company developing medicines to treat addiction and serious mental illnesses. He led Indivior's spin-off from its then parent company, Reckitt Benckiser, to become an independent, publicly traded company. Prior to joining Indivior, Mr. Claiborne served as the CFO of Sucampo Pharmaceuticals, Inc., a global biopharmaceutical company, which was later sold to Mallinckrodt. Before joining Sucampo, Mr. Claiborne served as CFO and Corporate Secretary of Osiris Therapeutics, Inc. during the company's initial public offering.Mr. Claiborne currently sits on the boards of NeuroSense Therapeutics, a clinical-stage drug development company that is advancing a treatment for people living with amyotrophic lateral sclerosis, and CytRx Corporation, a biopharmaceutical company focused on discovering and developing new cancer therapeutics. Mr. Claiborne graduated from Rutgers University with a B.A. in Business Administration and earned his M.B.A from Villanova University and was a National Association of Corporate Directors (NACD) Governance Fellow.Support the Show.

Jungen Erwachsenen in China wurde in ihrer Kindheit versprochen: Wer wie verrückt lernt, führt später ein goldenes Leben. Doch nach Jahrzehnten des Aufschwungs steckt Chinas Wirtschaft in einer anhaltenden Krise und das Aufstiegsversprechen gilt nicht mehr. Das bemerken vor allem junge, gut ausgebildete Menschen. Wie geht Chinas Generation Z, Gen Z, damit um? Wie hat sich das Leben für junge Menschen in China verändert? Darüber sprechen wir mit der ARD-Korrespondentin Marie von Mallinckrodt. Katja Drinhausen von der Forschungseinrichtung Meractor Institute for China Studies erklärt die Gründe und die Auswirkungen für die kriselnde chinesischen Wirtschaft. +++++++++++++++++++++++++++++++++++++++++++++++++ Die aktuelle Episode des Podcasts Welt.Macht.China: https://www.ardaudiothek.de/episode/welt-macht-china/leistungsdruck-in-china-top-ausgebildet-und-arbeitslos-24/ard/94754344/

Jungen Erwachsenen in China wurde in ihrer Kindheit versprochen: Wer wie verrückt lernt, führt später ein goldenes Leben. Doch nach Jahrzehnten des Aufschwungs steckt Chinas Wirtschaft in einer anhaltenden Krise und das Aufstiegsversprechen gilt nicht mehr. Das bemerken vor allem junge, gut ausgebildete Menschen. Wie geht Chinas Generation Z, Gen Z, damit um? Wie hat sich das Leben für junge Menschen in China verändert? Darüber sprechen wir mit der ARD-Korrespondentin Marie von Mallinckrodt. Katja Drinhausen von der Forschungseinrichtung Meractor Institute for China Studies erklärt die Gründe und die Auswirkungen für die kriselnde chinesischen Wirtschaft. +++++++++++++++++++++++++++++++++++++++++++++++++ Die aktuelle Episode des Podcasts Welt.Macht.China: https://www.ardaudiothek.de/episode/welt-macht-china/leistungsdruck-in-china-top-ausgebildet-und-arbeitslos-24/ard/94754344/

Synopsis: In this episode of BioTech 2050, Robert Ang, CEO of Vor Bio, shares insights on the current state of cancer therapies and next-gen modalities. He discusses Vor Bio's work on shielded stem cell transplants and CAR T-cell therapies targeting hematologic malignancies like AML and MDS. Robert also talks about his experience serving on boards and emphasizes the importance of core values in shaping organizational culture. He highlights his approach to hiring, focusing on finding individuals who are passionate about making an impact over titles. Overall, the discussion provides valuable insights into the evolving landscape of cancer treatment. Biography: Robert Ang, MBBS, MBA brings experience as a senior biotech executive and is formerly a physician, venture capitalist, and strategy consultant. Prior to Vor Bio, Robert was Chief Business Officer at Neon Therapeutics, serving as part of the early team that established the company prior to its Series A investment through IPO. Before Neon, he served as Senior Vice President of Business Development at Bavarian Nordic, where he was primarily responsible for conducting a $975 million transaction with Bristol-Myers Squibb for PROSTVAC, a Phase 3 immuno-oncology asset, and served as Head of Business Development and Medical Affairs for Cadence Pharmaceuticals. Robert also worked at Frazier Healthcare Ventures, a leading life sciences venture capital firm, where he was involved in several pharmaceutical and biotechnology investments including Cadence Pharmaceuticals (purchased by Mallinckrodt), Incline Therapeutics (purchased by The Medicines Company), Alnara Pharmaceuticals (purchased by Eli Lilly), and Collegium Pharmaceuticals. Robert also has strategy consulting experience at the Boston Consulting Group and has general surgical training. He holds an MBBS (Doctor of Medicine) from the University of Western Australia and an MBA with honors from Columbia Business School. Robert serves as the Board Chair of Enara Bio, a UK-based biotechnology company focused on non-classical HLA targets for immuno-oncology approaches. He is also a member of the Executive Committee of the Board of Directors of the Alliance for Regenerative Medicine (ARM), the leading international advocacy organization dedicated to realizing the promise of regenerative medicines and advanced therapies.

Welcome to our four-episode series: Raising Awareness of Hepatorenal Syndrome Acute Kidney Injury (HRS-AKI). In episode three, our host Muhamad Nadeem Yousaf, MD, speaks with Nikhilesh Mazumder, MD, MPH, Shilpa Junna, MD, and Pratima Sharma, MD, MBBS, MS, to discuss initial management of patients with HRS-AKI. They'll explore topics such as the efficacy of non-selective beta-blockers, the recommended plasma expander for those with decompensated cirrhosis, the roles of renal replacement therapy (RRT), TIPS, and extracorporeal liver support system (ELSS), and the significance of liver transplant in the context of HRS-AKI. Each episode of this series corresponds to a journal article from a September 2023 supplement of Clinical Gastroenterology and Hepatology (CGH), the official clinical practice journal of the American Gastroenterological Association, focusing on addressing knowledge gaps in HRS-AKI. To read the related journal articles and claim CME for listening, visit agau.gastro.org. This series is supported by an independent educational grant from Mallinckrodt

Welcome to our four-episode series: Raising Awareness of Hepatorenal Syndrome Acute Kidney Injury (HRS-AKI). In episode two, our host Muhamad Nadeem Yousaf, MD, speaks with Nikki Duong, MD, to discuss the nomenclature, pharmacological options, and care recommendations for HRS-AKI patients. Each episode of this series corresponds to a journal article from a September 2023 supplement of Clinical Gastroenterology and Hepatology (CGH), the official clinical practice journal of the American Gastroenterological Association, focusing on addressing knowledge gaps in HRS-AKI. To read the related journal articles and claim CME for listening, visit agau.gastro.org. This series is supported by an independent educational grant from Mallinckrodt

Welcome to our four-episode series: Raising Awareness of Hepatorenal Syndrome Acute Kidney Injury (HRS-AKI). In episode one, our host Muhamad Nadeem Yousaf, MD, speaks with Danielle Adebayo, MD, and Florence Wong, MD, MBBS, FRCPC, to analyze the pathophysiology of HRS-AKI. They cover peripheral vasodilatation hypothesis shortcomings in HRS-AKI, vasoconstrictor systems, bacterial translocation, inflammation, renal dysfunction, and contributory factors like cholemic nephropathy and adrenal insufficiency, while also suggesting the potential of metabolomic studies for future insights. Each episode of this series corresponds to a journal article from a September 2023 supplement of Clinical Gastroenterology and Hepatology (CGH), the official clinical practice journal of the American Gastroenterological Association, focusing on addressing knowledge gaps in HRS-AKI. To read the related journal articles and claim CME for listening, visit agau.gastro.org. This series is supported by an independent educational grant from Mallinckrodt

Welcome to our four-episode series: Raising Awareness of Hepatorenal Syndrome Acute Kidney Injury (HRS-AKI). In our final episode, our host Muhamad Nadeem Yousaf, MD, speaks with Vivian Ortiz, MD, and Neil Shah, MD, to delve into critical aspects of HRS-AKI. They cover the prognosis after initial management, the significance of reversing renal impairment for liver transplant candidates, the predictive role of MELD score in HRS-AKI, treatment's impact on liver transplant waiting lists, decision-making between liver transplant alone or simultaneous liver-kidney transplant, timing considerations for kidney transplant post-liver transplant, and factors affecting post-transplant prognosis. Each episode of this series corresponds to a journal article from a September 2023 supplement of Clinical Gastroenterology and Hepatology (CGH), the official clinical practice journal of the American Gastroenterological Association, focusing on addressing knowledge gaps in HRS-AKI. To read the related journal articles and claim CME for listening, visit agau.gastro.org. This series is supported by an independent educational grant from Mallinckrodt

In Re Mallinckrodt PLC

Welcome to the Daily Compliance News. Each day, Tom Fox, the Voice of Compliance brings you compliance-related stories to start your day. Sit back, enjoy a cup of morning coffee, and listen to the Daily Compliance News. All, from the Compliance Podcast Network. Each day we consider four stories from the business world, compliance, ethics, risk management, leadership, or general interest for the compliance professional. Stories we are following in today's edition: Mallinckrodt escapes SEC fine. (SEC) Biden announces Supply Chain Task Force. (Bloomberg) Holiday season=workplace romances? (FT) ABC slims down Chinese fatcats. (The Guardian) Learn more about your ad choices. Visit megaphone.fm/adchoices

Kenia ist nicht nur in Afrika ein Vorreiter bei erneuerbaren Energien. Mehr als 80 Prozent des Stroms liefern Geothermie, Wind, Wasser und Fotovoltaik. Aber auch Flüssiggas und Atomkraft sollen im künftigen Mix den Energiehunger befriedigen. David Ehl, Marie von Mallinckrodt, Andre Zantowwww.deutschlandfunkkultur.de, Weltzeit

Auf der Weltklimakonferenz in Dubai richten sich die Blicke, Hoffnungen und Erwartungen besonders auf ein Land: China. In absoluten Zahlen stößt das Land weltweit das meiste CO2 aus. China baut weiter Kohle ab, ist aber auch weltweiter Vorreiter in Erneuerbaren Energien. Von Marie von Mallinckrodt

China gilt als Pionier bei den Erneuerbaren Energien. In der Inneren Mongolei entsteht derzeit ein gigantischer Solarpark. Das Ziel: bis 2060 klimaneutral sein. Doch zugleich investiert China in den Kohleabbau, um Energievorräte zu sichern. Mallinckrodt, Marie; Lamby-Schmitt, Eva;Lamby-Schmitt, Evawww.deutschlandfunk.de, Hintergrund

Sind Strom-Engpässe der Grund für den Ausbau von Kohle und was bedeutet das für die Chinas Klimaziele? Marie von Mallinckrodt berichtet

Sind Strom-Engpässe der Grund für den Ausbau von Kohle und was bedeutet das für die Chinas Klimaziele? Marie von Mallinckrodt berichtet

Many burn survivors face the harsh reality after a burn injury of wondering if they will ever return back to ‘normal'. For many, the long journey to recovery can seem both overwhelming and uncertain—not knowing what the future can hold or how long recovery (both physical and emotional) may take. A burn survivor's journey to recovery is not often quick—and it can be in these moments of uncertainty that finding purpose and motivation can help survivors overcome some of their darkest moments. For Matt Manzari, a career in wakeskating that began at an early age seemed like what he was born to do. However, after two major traumatic events—a wakeskating water accident and an electrical burn injury, he was left not knowing what his future may hold. In this episode, we talk with Matt about his personal journey to recovery, how he found purpose after his accidents, and what returning back to ‘normal' meant for Matt. About Matt ManzariMatt Manzari fell in love with water sports at an early age. He started wakeskating and before he knew it, he was sponsored by Nike and traveling the world doing what he loved at the age of 15!  It seemed like his career was established, and Matt knew what he would do for the rest of his life! However, God had other plans and began to work on his heart. Matt went on to school to study Theology and four years laters, he was about to graduate and he and his wife were excited to move into full-time ministry. The weekend before his final exams, and even though he had pretty much removed himself from the sport, Matt entered into the pro tour contests to earn some extra money. However, tragedy struck and he was involved in an accident that doctors were amazed he survived. A year later, Matt began working in ministry. He was trimming trees at a local church and a power line arched over to the metal bucket he was standing in. 14,000 Volts shot through his body and caused 4th and 5th-degree burns, which melted most of the skin off of his chest and arms, going deep enough to kill muscle and bone. Matt was rushed to the emergency center and doctors were not sure if he would ever wake from the coma he was in. Miraculously, a few days later he woke up from the coma and began to speak. After multiple surgeries of tissue removal, artificial skin placement, and skin grafts, Matt was released just over three months later. Resources from the Show Visit Matt Manzari's Website.Purchase Matt's Book on Amazon.Learn More About Operation Wake Surf.Follow Matt on Facebook.Follow Matt on Instagram.Watch Matt on YouTube.Visit the Burn Community Bookshelf.Learn More About Phoenix Society's World Burn Congress.Watch ‘Finding Purpose After a Burn Injury'.Read the Article ‘Pain Management After a Burn Injury'.Watch ‘Telling Your Story to Make a Difference'.Download Your Free Copy of ‘A Caregiver's Guide to a Burn Injury'.Share Your Burn Survivor Story Online.Join the Online Burn Survivor Communities for Peer Support.Get Your Own Copy of Phoenix Society's Journey Magazine.For More Resources, Visit Us Here.About Mallinckrodt PharmaceuticalsFor more than 150 years, Mallinckrodt has been advancing the fields of science and medicine to improve the lives of people around the world. Learn more by visiting https://www.mallinckrodt.com.Sponsor Girls with Grafts Interested in becoming a sponsor of the show? Email us at info@phoenix-society.org. Enjoyed the show? Tell us on social media using hashtag #GirlswithGrafts and tagging Phoenix Society for Burn Survivors! 

This week's episode includes recaps of last week's Second Circuit ruling that $1.798 billion in syndicated leveraged loans to Millennium Health do not constitute “securities” covered by state and federal securities laws, Diamond Sports Group's previously sealed fraudulent transfer complaint against two JPMorgan entities and near-term restructurings in Mallinckrodt, Audacy, SmileDirectClub and Party City. And, as always, a preview of what's on the docket for this week. If you are not a Reorg subscriber, request access here: go.reorg-research.com/Podcast-Trial We're looking for feedback to improve the podcast experience! Please share your thoughts here: www.research.net/r/Reorg_podcast_survey For more information on our latest events and webinars: reorg.com/resources/events-and-webinars/ Sign up to our weekly newsletter Reorg on the Record: reorg.com/resources/reorg-on-the-record/ #highyield #leveragedfinance

This week's episode includes recaps of new coverage names Hawaiian Electric and Spirit AeroSystems, In-Court Action in Yellow Corp, FTX and Diamond Sports and potential restructurings from Mallinckrodt, Pure Fishing, Cano Health and Tenneco. And, as always, Reorg's Kate Thomas presents a preview of what's to come. If you are not a Reorg subscriber, request access here: go.reorg-research.com/Podcast-Trial We're looking for feedback to improve the podcast experience! Please share your thoughts here: www.research.net/r/Reorg_podcast_survey For more information on our latest events and webinars: reorg.com/resources/events-and-webinars/ Sign up to our weekly newsletter Reorg on the Record: reorg.com/resources/reorg-on-the-record/ #highyield #leveragedfinance

On this episode of Investor Connect, Hall welcomes Dr. Chris Apfel, Founder, CEO, & Chairman of the Board at SageMedic Corp. Located in Palo Alto, CA, USA, SageMedic Corp. (SAGE) is a cancer diagnostic company that brings precision medicine to the next level by overcoming the limitations of genomic testing. Specifically, because only 1 out of 4 patients have genomic mutations, in most cases oncologists don't have the tools to predict which therapy, if any, is likely to work for an individual patient. Hence, SAGE has developed the SAGE Oncotest™, a proprietary patent-protected ex-vivo, high-throughput 3D assay that predicts a patient's tumor response to traditional chemotherapies and targeted therapies, independently of any potential genetic mutations, and that within just 1 week.  With only $4.0M of funding SAGE has been able to develop this assay and is now a registered California lab that has very recently become fully accredited according to the Clinical Laboratory Improvement Amendments (CLIA) by the Commission on Office Laboratory Accreditation (COLA) and Center for Medicare and Medicaid Services (CMS), hence at the verge of starting commercialization to generate early revenue and clinical case studies.  Dr. Chris Apfel is an impact investor, and the Chair of the Life Sciences at the Northern California chapters of the Keiretsu Forum. He has led numerous due diligence efforts and has since made over 20+ investments in life science companies including Mission Bio, CorInnova, Pathware, Raydiant Oximetry, etc.  Before that, Dr. Apfel was an Executive Director of Cadence, where his health economic research on a non-reimbursable drug showed a $500 per patient cost savings after which Cadence was acquired for $1.3 billion by Mallinckrodt. Before he moved into the industry, he was a practicing clinician and professor at the University of California San Francisco (UCSF) with over 100 publications that have been cited over 20,000 times in the literature. Dr. Apfel received his MD/PhD from the University of Giessen, Germany, and his MBA from The Wharton School of Business, University of Pennsylvania, PA.  Dr. Chris shares the need for a strong and experienced team and game-changing technology, while also acknowledging the regulatory challenges in the life science space. He shares his belief that successful FDA approval can lead to high rewards and discusses the significance of reproducibility in academic research and the importance of forming independent opinions when evaluating startup opportunities. Visit SageMedic Corp at , and on . Reach out to Dr. Chris at , and on .   _______________________________________________________ For more episodes from Investor Connect, please visit the site at:    Check out our other podcasts here:   For Investors check out:   For Startups check out:   For eGuides check out:   For upcoming Events, check out    For Feedback please contact info@tencapital.group    Please , share, and leave a review. Music courtesy of .

Mallinckrodt, one of the country's largest opioid makers, is considering a plan to get out of paying more than $1 billion in settlement money to opioid victims. WSJ's Alexander Saeedy explains. Further Reading:  - Hedge Funds Seek to Cut Off $1 Billion Meant for Opioid Victims  Further Listening: - Purdue's $4.5 Billion Opioid Settlement Got Thrown Out. Now What?  - Two Days of Reckoning For Opioid Makers Learn more about your ad choices. Visit megaphone.fm/adchoices

Michigan AG files felony charges against 16 fake Trump electors | Missouri regulators say federal radioactive groundwater contamination efforts are not working | MO Gov Mike Parson signs bill easing restrictions on retired educators' ability to teach | Illinois Supreme Court rules SAFE-T Act Constitutional, making Illinois the first state to ban cash bail | Education Secretary Miguel Cardona announces 800,000 student loan borrowers to receive forgiveness in the next month. Support this show and all of the work in the Heartland POD universe by going to heartlandpod.com and clicking the patreon link to sign up. Membership starts at $1/month and goes up from there with extra shows and special access at the higher levels. Heartlandpod.com, click the patreon link or just go to Patreon and search for the heartland pod. No matter the level you choose, your membership helps us create these independent shows as we work together to change the conversation.INTRO: Welcome to Flyover View, a member of the Heartland Pod family of podcasts and a look at heartland news from 30,000 feet. I'm your host, Sean Diller, and I want to thank you for joining me today.Here we go! DETROIT NEWS:16 false Trump electors face felony charges in MichiganCraig MaugerBeth LeBlancThe Detroit NewsLansing — Attorney General Dana Nessel has filed felony charges against 16 Republicans who signed a certificate falsely stating that Donald Trump won Michigan's 2020 presidential election, launching criminal cases against top political figures inside the state GOP.Each of the 16 electors have been charged with eight felony counts, including forgery and conspiracy to commit election law forgery, according to Nessel's office.The revelation capped six months of investigation and produced the most serious allegations yet in Michigan over the campaign to overturn Trump's loss to Democrat Joe Biden in 2020. Biden won Michigan by 154,000 votes or 3 percentage points, but Trump and his supporters maintained false claims that fraud swung the result.As part of the push to undermine Biden's victory, Trump supporters gathered inside the Michigan Republican Party headquarters on Dec. 14, 2020, and signed a certificate, claiming to cast the state's 16 electoral votes for Trump.Eventually the false certificate was sent to the National Archives and Congress. The document falsely claimed the Trump electors had met inside the Michigan State Capitol on Dec. 14.  But that's not what happened. In fact Dec. 14 at the real state capitol is where the real electors met to cast their real electoral votes for the real winner, Joe Biden. The Michigan Attorney General said "The false electors' actions undermined the public's faith in the integrity of our elections and, we believe, also plainly violated the laws by which we administer our elections in Michigan.""My department has prosecuted numerous cases of election law violations throughout my tenure, and it would be malfeasance of the greatest magnitude if my department failed to act here in the face of overwhelming evidence of an organized effort to circumvent the lawfully cast ballots of millions of Michigan voters in a presidential election."Ryan Goodman, a law professor New York University School of Law, called the charges "a strong case" and noted the fake electors signed a sworn statement attesting "we convened and organized in the State Capitol.""In truth, they met (secretly) in GOP headquarters basement," Goodman wrote on Twitter.The felony complaints indicate the warrants for each of the electors were signed Thursday and Friday of last week, according to copies of the documents.The names and positions of the electors are available in news articles, and include several current and former state GOP committee chairs and local elected officials.Each of the 16 electors is charged with eight felonies: two counts of election law forgery; two counts of forgery; and one count each of uttering and publishing, conspiracy to commit forgery, conspiracy to commit election law forgery and conspiracy to commit forgery. Conspiracy to commit forgery carries one of the steepest penalties, punishable by up to 14 years in prison and a $10,000 fine.The conspiracy charges allege the defendants worked with specific named others to falsely make a public record: which was the false certificate of votes of the 2020 fake electors from Michigan.The 16 fake electors convened in the basement of Michigan GOP headquarters on Dec. 14, 2020, and produced a certificate that claimed Trump had won the state's 16 electoral votes.An affidavit prepared by Michigan AG Nessel's office in support of the complaint indicated Republican staffers in interviews with investigators said that non-electors were blocked from entering the building and the electors themselves were required to surrender their cellphones to prevent any recording of the event. GOP elector Mayra Rodriguez would later tell the Jan. 6 Select Committee that Trump campaign aide Shawn Flynn was present and spoke to the fake electors at the site.Attorney Ian Northon attempted to deliver a manila envelope similar to the size of the false electoral vote certificate to the Michigan Senate, claiming it contained the Republican electoral votes, the filing said. The U.S. National Archives and U.S. Senate Archives reported receiving a copy of the false certificate as well. Michigan election law bans someone from knowingly making or publishing a false document "with the intent to defraud."Each defendant, or their attorneys, has been notified of the charges, and the court will provide each with a date to appear in Ingham County district court for an arraignment. In a statement, AG Nessel's office also said "This remains an ongoing investigation, and the Michigan Department of Attorney General has not ruled out charges against additional defendants," Nessel's office said.YIKES: 14 years for conspiracy to commit forgery. And I'm not a practicing attorney, but I would bet anyone connected to Rudy Giuoini, Sydney Powell, Lindsey Graham, and some of these other goofballs could be looking at conspiracy charges as well. Because the tough thing about conspiracy crimes - so here it's conspiracy to commit election forgery and conspiracy to commit forgery - so the tough part if you're a defendant, is that once you talk with another person about the plan, and anyone involved takes even the smallest step toward moving on it, the crime of conspiracy is complete. You'll be found guilty if the prosecutor can prove it. MISSOURI INDEPENDENT: Something in the water.BY: ALLISON KITE - JULY 17, 2023 4:40 PM     A joint investigation by The Independent and MuckRock.In 2021, Missouri environmental regulators warned the federal government that radioactive contamination of groundwater from a uranium processing site near St. Louis was not improving despite cleanup efforts, according to documents reviewed by The Missouri Independent and MuckRock.Officials with the Missouri Department of Natural Resources wrote a letter to the U.S. Department of Energy in May 2021, responding to the agency's five-year review of its cleanup efforts at a Weldon Spring site where uranium was refined during the Cold War.While the radioactive waste and contaminated debris from the uranium processing site have been contained, Missouri regulators said contamination in the surrounding groundwater wasn't getting better.The letter, which has not been reported publicly, is the latest example of Missouri officials pushing the federal government to do more to protect the health of St. Louis-area residents near the litany of World War II and Cold War-era nuclear sites in the region. A six-month investigation by The Independent, MuckRock and The Associated Press found that federal agencies and private companies, for decades, downplayed concerns about radiological contamination or failed to investigate it fully at sites in St. Louis and St. Charles counties.St. Louis and surrounding areas played a key role in the development of the first atomic bomb during World War II. Uranium processed in downtown St. Louis was used in the first sustained nuclear reaction in Chicago. After the war, Mallinckrodt, which operated the downtown plant, started similar operations at a new facility on Missouri Highway 94 just north of the Missouri River.The more than 200-acre site has been contaminated for decades by radium, thorium and uranium as well as dangerous non-radioactive chemicals from its use to manufacture explosives and process uranium ore. The Weldon Spring plant was demolished and the debris buried, along with residue leftover from uranium processing, in a 41-acre containment cell covered with rock. The containment cell, the highest point in St. Charles County, is accessible to the public and has a monument to the communities displaced by the war effort and information on the cleanup effort at the top.Closer to the Missouri River, a quarry the federal government used to store radioactive waste was also contaminated. It's separated from the main site but part of the same cleanup and monitoring effort.Remediation of the plant is complete, but monitoring has shown uranium contamination is not decreasing. The Environmental Protection Agency shared some of the state's concerns that the groundwater monitoring network was insufficient and the groundwater is not projected to be restored in a reasonable timeframe. Beyond that, the state says, the extent of the contamination hasn't been sufficiently defined, meaning it could be more widespread than the Department of Energy knows based on its sampling. The federal sampling program, the state argues, is inadequate.Missouri regulators, in their letter, repeatedly corrected the Department of Energy when the federal agency said uranium levels were falling in groundwater wells at the site.In a response to the state, the federal government said it would revise its conclusion that the remedy was working. MISSOURI INDEPENDENT: Pulled out of retirementNew law tackles Missouri teacher shortage by encouraging retirees to return to classroomGov. Mike Parson signed legislation last week that allows educators to return to work without losing retirement benefitsBY: ANNELISE HANSHAW - JULY 13, 2023 9:00 AMMissouri's school districts are struggling - not just with a teacher shortage but a scarcity of bus drivers, custodians and other essential personnel.In the most recent school year, teachers with inadequate teaching certification taught over 8% of Missouri public school classes, according to the Missouri Department of Elementary and Secondary Education.The crisis has led larger school districts to consider adopting four-day school weeks to address teacher retention and recruitment problems.Sen. Rusty Black, R-Chillicothe, has been working on one way to address the problem for four years. And last week, the governor signed a bill into law, set to take effect Aug. 28, that will allow retired public-school staff to work full-time for a district for up to four years without losing retirement benefits.Prior to Black's legislation, teachers and non-certificated staff could work full-time for only two years post-retirement without losing benefits.The law also addresses other positions, like bus drivers and janitors. Retired school employees can work in positions that don't require a teaching certificate for more hours. CAPITOL NEWS ILLINOIS:UPDATED: Cash bail will end in Illinois as state supreme court rules the SAFE-T Act is constitutionalTuesday, July 18, 2023By JERRY NOWICKICapitol News Illinoisjnowicki@capitolnewsillinois.comSPRINGFIELD – A landmark criminal justice reform that eliminates cash bail in Illinois is constitutional, the state's Supreme Court ruled Tuesday, paving the way for the change to take effect Sept. 18. The 5-2 decision – handed down on partisan lines – means that an individual's wealth will no longer play a role in whether they are incarcerated while awaiting trial. Judges can still order someone to be detained as they await trial, but the new system will instead be based on an offender's level of risk of reoffending or fleeing prosecution. With the new law's implementation, Illinois will become the first state in the U.S. to fully eliminate cash bail – and all provisions of the SAFE-T Act criminal justice reform will have taken full effect.Short for Safety, Accountability, Fairness and Equity-Today, the wide-ranging measure was an initiative of the Illinois Legislative Black Caucus that passed in the wake of a nationwide reckoning with racism in the criminal justice system following the murder of George Floyd by a Minneapolis police officer.The act reformed police training, certification and use-of-force standards, expanded detainee rights, and gave the attorney general's office authority to investigate alleged civil rights violations by law enforcement. It also requires body cameras at all police departments by 2025. Some larger departments are already required to use body cameras under the law.State Rep. Justin Slaughter, a Chicago Democrat who sponsored the measure in the House, said the pretrial detention overhaul addresses an “overly punitive criminal justice system” for impoverished Illinoisans – especially those in Black and brown communities.It's a system that often forces innocent individuals to take plea deals – and to accept a criminal record – to obtain their freedom when they don't have money to post bail.“So this is not about being tough on crime or soft on crime,” he said. “This is about being smart on crime, reworking our system, streamlining our system to address those higher-level, more violent, dangerous alleged offenses. It's not about having someone unnecessarily sit in jail.”While opponents of the new law have argued it will strain smaller court systems and hinder judicial discretion, the lawsuit centered on the meaning of two mentions of the word “bail” in the Illinois Constitution, and the interplay between branches of government.The Supreme Court ruled on a set of consolidated cases filed against Illinois Attorney General Kwame Raoul, Gov. JB Pritzker and the state's Democratic legislative leaders by state's attorneys and sheriffs from over 60 counties.The lawsuit specifically cited Article VIII of the state constitution, which states, “all persons” accused of crimes “shall be bailable by sufficient sureties.” Any changes to the language, the lawsuit argued, would require a constitutional amendment to be approved by voters.While a Kankakee County judge ruled with the state's attorneys and sheriffs late last year, Chief Justice Mary Jane Theis, writing for the majority, said the lower court misinterpreted the state constitution..  She wrote, “The Illinois Constitution does not mandate that monetary bail is the only means to ensure criminal defendants appear for trials or the only means to protect the public,”Theis' majority opinion also said that the pretrial release provisions “expressly take crime victims into account.”“As we have already mentioned, those provisions require a court to consider the ‘nature and seriousness of the real and present threat to the safety of any person or persons that would be posed by the defendant's release,' including crime victims and their family members,” she wrote.  The pretrial detention changes – often referred to as the Pretrial Fairness Act, or PFA – will create a “presumption” in favor of pretrial release, meaning “the state bears the burden of establishing a defendant's eligibility for pretrial detention,” Theis wrote.Advocates say the intent of that provision is to divert lower-level nonviolent offenders from pretrial incarceration while giving judges authority to detain individuals accused of more serious crimes if they are deemed dangerous or at risk of fleeing prosecution.Another facet of the reform entitles defendants to a more intensive first appearance in court. During that appearance, defendants will now have a right to legal representation and prosecutors can detail their reasons for continued detention.The new hearings replace standard bail hearings, which often last less than five minutes and end with a judge deciding the conditions of release, including how much money the defendant must post to be released.Advocates for the bail reform have noted that it gives judges greater authority to detain individuals accused of crimes such as domestic battery and violations of orders of protection prior to trial than does prior law.Kaethe Morris Hoffer, the executive director of the Chicago Alliance Against Sexual Exploitation, spoke in favor of the reform at a virtual news conference Tuesday.  “I want to be clear – safety and interests and voices of people who have endured rape and violence in the sex trade have never been prioritized when the criminal legal system is asked to make decisions about the liberty of people who are accused of serious crimes of violence. This changes that.”While the new law directs law enforcement officers to cite and release anyone accused of a crime below a Class A misdemeanor, they would maintain discretion to make an arrest if the person is a threat or if making the arrest is necessary to prevent further lawbreaking.Lake County State's Attorney Eric Rinehart was one of two state's attorneys in Illinois who backed the SAFE-T Act alongside Cook County State's Attorney Kim Foxx. He noted that many smaller jurisdictions will lose revenue from cash bail payments when the system is eliminated – a point that reform advocates have repeatedly noted shows a flaw in the system.Capitol News Illinois is a nonprofit, nonpartisan news service covering state government. It is distributed to hundreds of print and broadcast outlets statewide. It is funded primarily by the Illinois Press Foundation and the Robert R. McCormick Foundation, along with major contributions from the Illinois Broadcasters Foundation and Southern Illinois Editorial Association.KANSAS REFLECTOR: Promises made, promises kept.White House announces more than 800,000 student loan borrowers to have debt forgiven. You heard that right. BY: ARIANA FIGUEROA - JULY 14, 2023 10:41 AM    WASHINGTON — The $39 billion in debt relief will come through fixes to mismanagement of the agency's income-driven repayment plans. Many long-time borrowers, including those who had been making payments for 20 years or more, were denied relief they were eligible for under the repayment plans. This happens when qualified payments were made but aren't being counted accurately. U.S. Secretary of Education Miguel Cardona said in a statement.“For far too long, borrowers fell through the cracks of a broken system that failed to keep accurate track of their progress towards forgiveness,” The Department of Education has already begun to notify those 804,000 borrowers of their forgiveness, and within 30 days their debts will be wiped out.The plan includes borrowers with Direct Loans or Federal Family Education Loans held by the department who have reached a forgiveness threshold specified by the department.Cardona said “By fixing past administrative failures, we are ensuring everyone gets the forgiveness they deserve, just as we have already done for public servants, students who were cheated by their colleges, veterans and other borrowers with permanent disabilities”A 2022 NPR investigation found numerous problems with the agency's handling of IDR plans, which are meant to help low-income borrowers. Loan servicers failed to keep track of borrowers' progress toward forgiveness and payment histories were not properly transferred from one loan servicer to another. In January of this year, The Department of Education announced plans to overhaul the income-driven repayment plan.Under the new plan, monthly payments would decline to 5% of a borrower's income — down from 10% — and the repayment timeline for loan forgiveness would be decreased to 10 years from 20 or 25 if the initial loan is less than $12,000.The announcement Friday followed the Supreme Court's decision in late June to strike down the Biden administration's student debt relief program that would have canceled up to $20,000 in student loan debt for some borrowers.Under the Biden administration, the Department of Education has canceled about $116 billion in student loan debt for borrowers who were misled by for-profit institutions, borrowers with disabilities and those with loans in the Public Service Loan Forgiveness program.Welp, that's it for me. From Denver I'm Sean Diller, original reporting for the stories in todays show is from Capitol News Illinois, Missouri Independent, Detroit News, and Kansas Reflector.

Michigan AG files felony charges against 16 fake Trump electors | Missouri regulators say federal radioactive groundwater contamination efforts are not working | MO Gov Mike Parson signs bill easing restrictions on retired educators' ability to teach | Illinois Supreme Court rules SAFE-T Act Constitutional, making Illinois the first state to ban cash bail | Education Secretary Miguel Cardona announces 800,000 student loan borrowers to receive forgiveness in the next month. Support this show and all of the work in the Heartland POD universe by going to heartlandpod.com and clicking the patreon link to sign up. Membership starts at $1/month and goes up from there with extra shows and special access at the higher levels. Heartlandpod.com, click the patreon link or just go to Patreon and search for the heartland pod. No matter the level you choose, your membership helps us create these independent shows as we work together to change the conversation.INTRO: Welcome to Flyover View, a member of the Heartland Pod family of podcasts and a look at heartland news from 30,000 feet. I'm your host, Sean Diller, and I want to thank you for joining me today.Here we go! DETROIT NEWS:16 false Trump electors face felony charges in MichiganCraig MaugerBeth LeBlancThe Detroit NewsLansing — Attorney General Dana Nessel has filed felony charges against 16 Republicans who signed a certificate falsely stating that Donald Trump won Michigan's 2020 presidential election, launching criminal cases against top political figures inside the state GOP.Each of the 16 electors have been charged with eight felony counts, including forgery and conspiracy to commit election law forgery, according to Nessel's office.The revelation capped six months of investigation and produced the most serious allegations yet in Michigan over the campaign to overturn Trump's loss to Democrat Joe Biden in 2020. Biden won Michigan by 154,000 votes or 3 percentage points, but Trump and his supporters maintained false claims that fraud swung the result.As part of the push to undermine Biden's victory, Trump supporters gathered inside the Michigan Republican Party headquarters on Dec. 14, 2020, and signed a certificate, claiming to cast the state's 16 electoral votes for Trump.Eventually the false certificate was sent to the National Archives and Congress. The document falsely claimed the Trump electors had met inside the Michigan State Capitol on Dec. 14.  But that's not what happened. In fact Dec. 14 at the real state capitol is where the real electors met to cast their real electoral votes for the real winner, Joe Biden. The Michigan Attorney General said "The false electors' actions undermined the public's faith in the integrity of our elections and, we believe, also plainly violated the laws by which we administer our elections in Michigan.""My department has prosecuted numerous cases of election law violations throughout my tenure, and it would be malfeasance of the greatest magnitude if my department failed to act here in the face of overwhelming evidence of an organized effort to circumvent the lawfully cast ballots of millions of Michigan voters in a presidential election."Ryan Goodman, a law professor New York University School of Law, called the charges "a strong case" and noted the fake electors signed a sworn statement attesting "we convened and organized in the State Capitol.""In truth, they met (secretly) in GOP headquarters basement," Goodman wrote on Twitter.The felony complaints indicate the warrants for each of the electors were signed Thursday and Friday of last week, according to copies of the documents.The names and positions of the electors are available in news articles, and include several current and former state GOP committee chairs and local elected officials.Each of the 16 electors is charged with eight felonies: two counts of election law forgery; two counts of forgery; and one count each of uttering and publishing, conspiracy to commit forgery, conspiracy to commit election law forgery and conspiracy to commit forgery. Conspiracy to commit forgery carries one of the steepest penalties, punishable by up to 14 years in prison and a $10,000 fine.The conspiracy charges allege the defendants worked with specific named others to falsely make a public record: which was the false certificate of votes of the 2020 fake electors from Michigan.The 16 fake electors convened in the basement of Michigan GOP headquarters on Dec. 14, 2020, and produced a certificate that claimed Trump had won the state's 16 electoral votes.An affidavit prepared by Michigan AG Nessel's office in support of the complaint indicated Republican staffers in interviews with investigators said that non-electors were blocked from entering the building and the electors themselves were required to surrender their cellphones to prevent any recording of the event. GOP elector Mayra Rodriguez would later tell the Jan. 6 Select Committee that Trump campaign aide Shawn Flynn was present and spoke to the fake electors at the site.Attorney Ian Northon attempted to deliver a manila envelope similar to the size of the false electoral vote certificate to the Michigan Senate, claiming it contained the Republican electoral votes, the filing said. The U.S. National Archives and U.S. Senate Archives reported receiving a copy of the false certificate as well. Michigan election law bans someone from knowingly making or publishing a false document "with the intent to defraud."Each defendant, or their attorneys, has been notified of the charges, and the court will provide each with a date to appear in Ingham County district court for an arraignment. In a statement, AG Nessel's office also said "This remains an ongoing investigation, and the Michigan Department of Attorney General has not ruled out charges against additional defendants," Nessel's office said.YIKES: 14 years for conspiracy to commit forgery. And I'm not a practicing attorney, but I would bet anyone connected to Rudy Giuoini, Sydney Powell, Lindsey Graham, and some of these other goofballs could be looking at conspiracy charges as well. Because the tough thing about conspiracy crimes - so here it's conspiracy to commit election forgery and conspiracy to commit forgery - so the tough part if you're a defendant, is that once you talk with another person about the plan, and anyone involved takes even the smallest step toward moving on it, the crime of conspiracy is complete. You'll be found guilty if the prosecutor can prove it. MISSOURI INDEPENDENT: Something in the water.BY: ALLISON KITE - JULY 17, 2023 4:40 PM     A joint investigation by The Independent and MuckRock.In 2021, Missouri environmental regulators warned the federal government that radioactive contamination of groundwater from a uranium processing site near St. Louis was not improving despite cleanup efforts, according to documents reviewed by The Missouri Independent and MuckRock.Officials with the Missouri Department of Natural Resources wrote a letter to the U.S. Department of Energy in May 2021, responding to the agency's five-year review of its cleanup efforts at a Weldon Spring site where uranium was refined during the Cold War.While the radioactive waste and contaminated debris from the uranium processing site have been contained, Missouri regulators said contamination in the surrounding groundwater wasn't getting better.The letter, which has not been reported publicly, is the latest example of Missouri officials pushing the federal government to do more to protect the health of St. Louis-area residents near the litany of World War II and Cold War-era nuclear sites in the region. A six-month investigation by The Independent, MuckRock and The Associated Press found that federal agencies and private companies, for decades, downplayed concerns about radiological contamination or failed to investigate it fully at sites in St. Louis and St. Charles counties.St. Louis and surrounding areas played a key role in the development of the first atomic bomb during World War II. Uranium processed in downtown St. Louis was used in the first sustained nuclear reaction in Chicago. After the war, Mallinckrodt, which operated the downtown plant, started similar operations at a new facility on Missouri Highway 94 just north of the Missouri River.The more than 200-acre site has been contaminated for decades by radium, thorium and uranium as well as dangerous non-radioactive chemicals from its use to manufacture explosives and process uranium ore. The Weldon Spring plant was demolished and the debris buried, along with residue leftover from uranium processing, in a 41-acre containment cell covered with rock. The containment cell, the highest point in St. Charles County, is accessible to the public and has a monument to the communities displaced by the war effort and information on the cleanup effort at the top.Closer to the Missouri River, a quarry the federal government used to store radioactive waste was also contaminated. It's separated from the main site but part of the same cleanup and monitoring effort.Remediation of the plant is complete, but monitoring has shown uranium contamination is not decreasing. The Environmental Protection Agency shared some of the state's concerns that the groundwater monitoring network was insufficient and the groundwater is not projected to be restored in a reasonable timeframe. Beyond that, the state says, the extent of the contamination hasn't been sufficiently defined, meaning it could be more widespread than the Department of Energy knows based on its sampling. The federal sampling program, the state argues, is inadequate.Missouri regulators, in their letter, repeatedly corrected the Department of Energy when the federal agency said uranium levels were falling in groundwater wells at the site.In a response to the state, the federal government said it would revise its conclusion that the remedy was working. MISSOURI INDEPENDENT: Pulled out of retirementNew law tackles Missouri teacher shortage by encouraging retirees to return to classroomGov. Mike Parson signed legislation last week that allows educators to return to work without losing retirement benefitsBY: ANNELISE HANSHAW - JULY 13, 2023 9:00 AMMissouri's school districts are struggling - not just with a teacher shortage but a scarcity of bus drivers, custodians and other essential personnel.In the most recent school year, teachers with inadequate teaching certification taught over 8% of Missouri public school classes, according to the Missouri Department of Elementary and Secondary Education.The crisis has led larger school districts to consider adopting four-day school weeks to address teacher retention and recruitment problems.Sen. Rusty Black, R-Chillicothe, has been working on one way to address the problem for four years. And last week, the governor signed a bill into law, set to take effect Aug. 28, that will allow retired public-school staff to work full-time for a district for up to four years without losing retirement benefits.Prior to Black's legislation, teachers and non-certificated staff could work full-time for only two years post-retirement without losing benefits.The law also addresses other positions, like bus drivers and janitors. Retired school employees can work in positions that don't require a teaching certificate for more hours. CAPITOL NEWS ILLINOIS:UPDATED: Cash bail will end in Illinois as state supreme court rules the SAFE-T Act is constitutionalTuesday, July 18, 2023By JERRY NOWICKICapitol News Illinoisjnowicki@capitolnewsillinois.comSPRINGFIELD – A landmark criminal justice reform that eliminates cash bail in Illinois is constitutional, the state's Supreme Court ruled Tuesday, paving the way for the change to take effect Sept. 18. The 5-2 decision – handed down on partisan lines – means that an individual's wealth will no longer play a role in whether they are incarcerated while awaiting trial. Judges can still order someone to be detained as they await trial, but the new system will instead be based on an offender's level of risk of reoffending or fleeing prosecution. With the new law's implementation, Illinois will become the first state in the U.S. to fully eliminate cash bail – and all provisions of the SAFE-T Act criminal justice reform will have taken full effect.Short for Safety, Accountability, Fairness and Equity-Today, the wide-ranging measure was an initiative of the Illinois Legislative Black Caucus that passed in the wake of a nationwide reckoning with racism in the criminal justice system following the murder of George Floyd by a Minneapolis police officer.The act reformed police training, certification and use-of-force standards, expanded detainee rights, and gave the attorney general's office authority to investigate alleged civil rights violations by law enforcement. It also requires body cameras at all police departments by 2025. Some larger departments are already required to use body cameras under the law.State Rep. Justin Slaughter, a Chicago Democrat who sponsored the measure in the House, said the pretrial detention overhaul addresses an “overly punitive criminal justice system” for impoverished Illinoisans – especially those in Black and brown communities.It's a system that often forces innocent individuals to take plea deals – and to accept a criminal record – to obtain their freedom when they don't have money to post bail.“So this is not about being tough on crime or soft on crime,” he said. “This is about being smart on crime, reworking our system, streamlining our system to address those higher-level, more violent, dangerous alleged offenses. It's not about having someone unnecessarily sit in jail.”While opponents of the new law have argued it will strain smaller court systems and hinder judicial discretion, the lawsuit centered on the meaning of two mentions of the word “bail” in the Illinois Constitution, and the interplay between branches of government.The Supreme Court ruled on a set of consolidated cases filed against Illinois Attorney General Kwame Raoul, Gov. JB Pritzker and the state's Democratic legislative leaders by state's attorneys and sheriffs from over 60 counties.The lawsuit specifically cited Article VIII of the state constitution, which states, “all persons” accused of crimes “shall be bailable by sufficient sureties.” Any changes to the language, the lawsuit argued, would require a constitutional amendment to be approved by voters.While a Kankakee County judge ruled with the state's attorneys and sheriffs late last year, Chief Justice Mary Jane Theis, writing for the majority, said the lower court misinterpreted the state constitution..  She wrote, “The Illinois Constitution does not mandate that monetary bail is the only means to ensure criminal defendants appear for trials or the only means to protect the public,”Theis' majority opinion also said that the pretrial release provisions “expressly take crime victims into account.”“As we have already mentioned, those provisions require a court to consider the ‘nature and seriousness of the real and present threat to the safety of any person or persons that would be posed by the defendant's release,' including crime victims and their family members,” she wrote.  The pretrial detention changes – often referred to as the Pretrial Fairness Act, or PFA – will create a “presumption” in favor of pretrial release, meaning “the state bears the burden of establishing a defendant's eligibility for pretrial detention,” Theis wrote.Advocates say the intent of that provision is to divert lower-level nonviolent offenders from pretrial incarceration while giving judges authority to detain individuals accused of more serious crimes if they are deemed dangerous or at risk of fleeing prosecution.Another facet of the reform entitles defendants to a more intensive first appearance in court. During that appearance, defendants will now have a right to legal representation and prosecutors can detail their reasons for continued detention.The new hearings replace standard bail hearings, which often last less than five minutes and end with a judge deciding the conditions of release, including how much money the defendant must post to be released.Advocates for the bail reform have noted that it gives judges greater authority to detain individuals accused of crimes such as domestic battery and violations of orders of protection prior to trial than does prior law.Kaethe Morris Hoffer, the executive director of the Chicago Alliance Against Sexual Exploitation, spoke in favor of the reform at a virtual news conference Tuesday.  “I want to be clear – safety and interests and voices of people who have endured rape and violence in the sex trade have never been prioritized when the criminal legal system is asked to make decisions about the liberty of people who are accused of serious crimes of violence. This changes that.”While the new law directs law enforcement officers to cite and release anyone accused of a crime below a Class A misdemeanor, they would maintain discretion to make an arrest if the person is a threat or if making the arrest is necessary to prevent further lawbreaking.Lake County State's Attorney Eric Rinehart was one of two state's attorneys in Illinois who backed the SAFE-T Act alongside Cook County State's Attorney Kim Foxx. He noted that many smaller jurisdictions will lose revenue from cash bail payments when the system is eliminated – a point that reform advocates have repeatedly noted shows a flaw in the system.Capitol News Illinois is a nonprofit, nonpartisan news service covering state government. It is distributed to hundreds of print and broadcast outlets statewide. It is funded primarily by the Illinois Press Foundation and the Robert R. McCormick Foundation, along with major contributions from the Illinois Broadcasters Foundation and Southern Illinois Editorial Association.KANSAS REFLECTOR: Promises made, promises kept.White House announces more than 800,000 student loan borrowers to have debt forgiven. You heard that right. BY: ARIANA FIGUEROA - JULY 14, 2023 10:41 AM    WASHINGTON — The $39 billion in debt relief will come through fixes to mismanagement of the agency's income-driven repayment plans. Many long-time borrowers, including those who had been making payments for 20 years or more, were denied relief they were eligible for under the repayment plans. This happens when qualified payments were made but aren't being counted accurately. U.S. Secretary of Education Miguel Cardona said in a statement.“For far too long, borrowers fell through the cracks of a broken system that failed to keep accurate track of their progress towards forgiveness,” The Department of Education has already begun to notify those 804,000 borrowers of their forgiveness, and within 30 days their debts will be wiped out.The plan includes borrowers with Direct Loans or Federal Family Education Loans held by the department who have reached a forgiveness threshold specified by the department.Cardona said “By fixing past administrative failures, we are ensuring everyone gets the forgiveness they deserve, just as we have already done for public servants, students who were cheated by their colleges, veterans and other borrowers with permanent disabilities”A 2022 NPR investigation found numerous problems with the agency's handling of IDR plans, which are meant to help low-income borrowers. Loan servicers failed to keep track of borrowers' progress toward forgiveness and payment histories were not properly transferred from one loan servicer to another. In January of this year, The Department of Education announced plans to overhaul the income-driven repayment plan.Under the new plan, monthly payments would decline to 5% of a borrower's income — down from 10% — and the repayment timeline for loan forgiveness would be decreased to 10 years from 20 or 25 if the initial loan is less than $12,000.The announcement Friday followed the Supreme Court's decision in late June to strike down the Biden administration's student debt relief program that would have canceled up to $20,000 in student loan debt for some borrowers.Under the Biden administration, the Department of Education has canceled about $116 billion in student loan debt for borrowers who were misled by for-profit institutions, borrowers with disabilities and those with loans in the Public Service Loan Forgiveness program.Welp, that's it for me. From Denver I'm Sean Diller, original reporting for the stories in todays show is from Capitol News Illinois, Missouri Independent, Detroit News, and Kansas Reflector.

This week's episode also includes recaps of the district court decision reversing a Sept. 2022 Intelsat bankruptcy decision disallowing $421 million in claims, a stay of the Serta debtors' plan confirmation and Mallinckrodt's extension of the deadline to make opioid deferred cash payments under its plan. Also, we feature updates on Trinseo, Rite Aid and Wheels Up's retention of restructuring and financial advisors. And, as always, a preview of what's coming next week. Reorg is always looking for feedback to help us improve the podcast experience. Please take a moment to complete this short survey and let us know how we're doing. www.research.net/r/Reorg_podcast_survey

Welcome to the award-winning FCPA Compliance Report, the longest running podcast in compliance. In this episode, I am joined by with Mary Inman, partner at Constantine Cannon. We discuss the recently released US Fraud statistics and preventative measures with Inman. Inman explains that the US Department of Justice put out statistics on the False Claims Act for 2022, with healthcare dominating the recovered funds. Inman goes on to discuss how whistleblowers can still launch cases, even if the government does not join in, as well as encourage listeners to report fraud to their respective insurance department if it later results in higher premiums for their organization. Key Topics: ·      The Increase of Managed Care Plans in Medicare [00:05:16] ·       The Power of Whistleblowing and the Impact of Joining Government Cases [00:09:19] ·      Medicare and Medicaid Fraud in California and Florida [00:13:21] ·       Impact of Insurance Fraud on Premiums [00:17:44] ·      The False Claims Act and the Escobar Decision [00:26:09] Notable Quotes 1.      "And they were basically paying kickbacks to their they know who the physicians are, who are their largest prescribers of their drugs. And they were paying kickbacks to encourage them to basically discourage them from prescribing their competitors' products and to direct it to them."  2.     "What happened here is that Mallinckrodt improperly calculated their rebate by claiming that drug that they developed in 1990 was actually termed a new drug in 2013. And so that allowed them to greatly decrease the amount of the rebate that they would have owed to the Medicaid program.""  3.    "It's another kind of false billing scenario. It was notable to me that we had 2 big settlements." 4.     "The whistleblower had accused the Association of basically shifting costs that it shouldn't have been reimbursing onto the Florida Medicaid program.   Resources: Mary Inman on Linkedin Constantine Cannon Tom Fox on LinkedIn Learn more about your ad choices. Visit megaphone.fm/adchoices

Henrico County soon will receive just more than ,000 as part of the first payment from opioid manufacturer Mallinckrodt to Virginia, which the state will receive this week. The company's initial .488 million payment will be divided three ways, with the state receiving just more than 3,000, the Virginia Opioid Abatement Authority receiving [post_excerpt].918 million, and localities splitting just more than [post_excerpt] million. Henrico will receive about 4.47% of the latter amount, or ,813.67. This payment from Mallinckrodt is the first from an expected .6 million during the next eight years, assuming Mallinckrodt does not prepay the settlement. Should it...Article LinkSupport the show

Weltweit schafft es niemand so einzigartige Chips zu produzieren wie Taiwan: hochentwickelte, mini-kleine Bauteile, die eigentlich in allen elektronischen Geräten stecken – in unseren Handys, Autos, sogar im Kühlschrank. Alle brauchen diese Chips. Wir sind von ihnen abhängig. Deswegen ist um diese Chips ein weltweites Wettrennen entbrannt. Und dieses Rennen wird immer aggressiver. Für Taiwan könnten die Chips eine Lebensversicherung sein. Aber an ihnen könnte sich auch ein Krieg entzünden. Und wenn Ihr Euch fragt, ob Euer neuestes Handy noch rechtzeitig vor Heiligabend geliefert wird, dann könnte das auch ein Vorgeschmack darauf sein, was vielleicht noch kommt. Komplexes Thema, aber Moderator Philipp Abresch lässt es sich von seinen drei Korrespondentinnen-Kollegen erklären. Dabei sind Gudrun Engel in Washington, Ulrich Mendgen in Tokio und Marie von Mallinckrodt in Peking. Ein Gespräch über alle Zeitzonen hinweg. Es ist ja auch ein durch und durch globales Thema.

This episode is a replay of Episode 13 which originally aired on September 7, 2022.   Sheppard Mullin's Restructure THIS! podcast explores the latest trends and controversies in chapter 11 bankruptcy, commercial insolvency, and distressed investing. In this week's episode, we're joined by Cullen Drescher Speckhart, Chair of Cooley's business restructuring & reorganization practice and partner in charge of its Washington, DC office, and Rachel Ehrlich Albanese, Chair of DLA Piper's U.S. Restructuring practice and a partner in the firm's New York office, to discuss the ever-present challenge of recruiting, retaining and advancing women lawyers and professionals in the restructuring industry.   What We Discussed in this Episode:   Men account for a majority of the lawyers and other professionals in the restructuring industry. What explains this lack of parity? Is having women in leadership positions important to encouraging other women to aspire to those heights? As head of your respective firm's restructuring groups, what are your observations regarding women's experiences in law today? Do you spend time, energy and effort helping men in your group understand the contributions women attorneys and professionals can make?  Can you tell us a bit about your personal development and how you each came to be the woman you are today? What has had the most significant impact on your success in the restructuring industry? What should law firm leaders focus on as they work to improve gender parity going forward? Rachel Ehrlich Albanese Rachel is Chair of DLA Piper's U.S. Restructuring practice and a partner in the firm's New York office. She has nearly 20 years of experience representing secured and unsecured creditors, debtors, equity holders, purchasers of distressed assets, and other parties in interest in a wide range of restructuring matters, including cases under chapter 11 of the U.S. Bankruptcy Code, out-of-court workouts, and cross-border insolvency proceedings.    Rachel has been involved in Puerto Rico's current restructuring efforts since their earliest days when she participated in dozens of meetings with U.S. Congress members and staff to develop the law that ultimately became PROMESA. She has subsequently been instrumental in many of DLA Piper's PROMESA-related matters.   About Cullen Drescher Speckhart Cullen is Chair of Cooley's business restructuring & reorganization practice and partner in charge of its Washington, DC office. She is a top advocate in corporate restructuring and financial litigation, with a diverse practice spanning a range of industries, including healthcare, life sciences, technology, energy, and retail.    In addition to her deep experience in complex insolvency litigation, Cullen has led some of the largest and most significant restructuring engagements in a multitude of jurisdictions, including serving as lead restructuring counsel to official creditor constituencies in Mallinckrodt and LTL Management (Johnson & Johnson), Le Tote, and 24 Hour Fitness.   Contact Information   Cullen Drescher Speckhart   Rachel Ehrlich Albanese   Resources   "Rachel Albanese Speaks On Independent Directors" Thank you for listening! Don't forget to SUBSCRIBE to the show to receive every new episode delivered straight to your podcast player every week.   If you enjoyed this episode, please help us get the word out about this podcast. Rate and Review this show in Apple Podcasts, Amazon Music, Google Podcasts, Stitcher or Spotify.  It helps other listeners find this show. This podcast is for informational and educational purposes only. It is not to be construed as legal advice specific to your circumstances. If you need help with any legal matter, be sure to consult with an attorney regarding your specific needs.

Sheppard Mullin's Restructure THIS! podcast explores the latest trends and controversies in chapter 11 bankruptcy, commercial insolvency, and distressed investing. In this week's episode, we're joined by Cullen Drescher Speckhart, Chair of Cooley's business restructuring & reorganization practice and partner in charge of its Washington, DC office, and Rachel Ehrlich Albanese, Chair of DLA Piper's U.S. Restructuring practice and a partner in the firm's New York office, to discuss the ever-present challenge of recruiting, retaining and advancing women lawyers and professionals in the restructuring industry.   What We Discussed in this Episode:   Men account for a majority of the lawyers and other professionals in the restructuring industry. What explains this lack of parity? Is having women in leadership positions important to encouraging other women to aspire to those heights? As head of your respective firm's restructuring groups, what are your observations regarding women's experiences in law today? Do you spend time, energy and effort helping men in your group understand the contributions women attorneys and professionals can make?  Can you tell us a bit about your personal development and how you each came to be the woman you are today? What has had the most significant impact on your success in the restructuring industry? What should law firm leaders focus on as they work to improve gender parity going forward? About Rachel Ehrlich Albanese Rachel is Chair of DLA Piper's U.S. Restructuring practice and a partner in the firm's New York office. She has nearly 20 years of experience representing secured and unsecured creditors, debtors, equity holders, purchasers of distressed assets, and other parties in interest in a wide range of restructuring matters, including cases under chapter 11 of the U.S. Bankruptcy Code, out-of-court workouts, and cross-border insolvency proceedings.    Rachel has been involved in Puerto Rico's current restructuring efforts since their earliest days when she participated in dozens of meetings with U.S. Congress members and staff to develop the law that ultimately became PROMESA. She has subsequently been instrumental in many of DLA Piper's PROMESA-related matters.   About Cullen Drescher Speckhart Cullen is Chair of Cooley's business restructuring & reorganization practice and partner in charge of its Washington, DC office. She is a top advocate in corporate restructuring and financial litigation, with a diverse practice spanning a range of industries, including healthcare, life sciences, technology, energy, and retail.    In addition to her deep experience in complex insolvency litigation, Cullen has led some of the largest and most significant restructuring engagements in a multitude of jurisdictions, including serving as lead restructuring counsel to official creditor constituencies in Mallinckrodt and LTL Management (Johnson & Johnson), Le Tote, and 24 Hour Fitness.   Contact Information   Cullen Drescher Speckhart   Rachel Ehrlich Albanese   Resources   "Rachel Albanese Speaks On Independent Directors"

This Day in Maine Friday, August 12, 2022.

This week we take a look at Crédito Real, LATAM Airlines, TPC Group and Mallinckrodt. We are taking a brief recess from our weekly Deep Dive but will be back next week with more premium content.

Dr. Michelle Miller Thomas is associate professor at the Washington University in St. Louis and she specialises in diagnostic neuroradiology. She works between multiple hospitals in the St. Louis area. She did her intern year at Saint Johns Mercy Medical Center in St. Louis MO, then her residency in diagnostic radiology at the University of Texas Houston and her fellowship in neuroradiology at the Mallinckrodt Institute of Radiology at Washington University School of Medicine in St. Louis MO. Radiology education is one of her major interests. Her experience weaves together expertise in medical education and translational imaging research. She develops curricula, leads groups of physician-clinician educators and delivers courses for undergraduate and graduate medical trainees. She has expertise in translating advanced neuroimaging techniques from the laboratory into clinical applications. The major focus of the advanced neuroimaging topics she studies are brain tumour characterisation, neurosurgical planning, and dementia. She is 13 years in practice and looking forward to many more.

A cache of more than 1.4 million newly released records exposes the inner workings of the nation's largest opioid manufacturer. Today on “Post Reports,” we go inside the sales machine at Mallinckrodt.Read more:The largest manufacturer of opioids in the United States once cultivated a reliable stable of hundreds of doctors it could count on to write a steady stream of prescriptions for pain pills.But one left the United States for Pakistan months before he was indicted on federal drug conspiracy and money laundering charges. Another was barred from practicing medicine after several of his patients died of drug overdoses. Another tried to leave the country in the face of charges that he was operating illegal pill dispensing operations, or pill mills, in two states. He was arrested and sent to prison for eight years.These doctors were among 239 medical professionals ranked by Mallinckrodt Pharmaceuticals as its top prescribers of opioids during the height of the pain pill epidemic, in 2013. That year, more than 14,000 Americans died of prescription opioid overdoses.More than a quarter of those prescribers — 65 — were later convicted of crimes related to their medical practices, had their medical licenses suspended or revoked, or paid state or federal fines after being accused of wrongdoing, according to a Washington Post analysis of previously confidential Mallinckrodt documents and emails, along with criminal and civil background checks of the doctors. Between April and September of that year, Mallinckrodt's sales representatives contacted those 239 prescribers more than 7,000 times.The documents, made public after years of litigation and bankruptcy proceedings, shed new light on how aggressively Mallinckrodt sought to increase its market share as the epidemic was raging.Meryl Kornfield and Scott Higham report.

Featured this week: LATAM, Mallinckrodt, Footprint Power and Cooper Standard. Also a replay of Reorg's February Webinar where Reorg's First Day team and Kirkland & Ellis' Joshua Sussberg, in a conversation moderated by John Hartgen, public affairs officer at the American Bankruptcy Institute.

Featuring: Peloton, AMC, Mallinckrodt and Surprise Medical Billing legislation. For this week's Deep Dive, Reorg's Mike Legge, Karen Leung and David Mayo join us to discuss the current state of play of third-party releases in bankruptcy, reviewing recent decisions in Purdue Pharma, Ascena Retail and Mallinckrodt, as well as reviewing the ongoing case of LTL Management and other “Texas two-step” bankruptcies.

Egresada del Mallinckrodt de Martínez (y en 1984 estudiante del ciclo básico de la UBA para seguir Abogacía), María Eugenia Amorosino demostró su capacidad para la escritura con este cuento que relata una historia que sucede en una casa cerca de la suya, aunque no tiene río, hermosa e inalcanzable, real en estos aspectos, pero ficticia en cuanto a lo que acontece. En "Veinte jóvenes cuentistas argentinos", se destaca su pasión por la literatura y su apego por autores como Wilde, las historias policiales y "una gran fidelidad a Bécquer" Espero que les guste, y que disfruten tanto como yo de la historia.

Featuring Puerto Rico, Cineworld, Transocean and Mallinckrodt. And for our Deep Dive, Americas Core Credit Legal Analyst Sean Daly returns to follow up last week's discussion of bankruptcy lockup and voting agreements in the Grupo Aeroméxico and LATAM bankruptcies to give an update on some important recent developments in both cases.

On this week's Americas Core Credit podcast we take a look at Mallinckrodt, Intelsat, Ferrellgas Partners, CM Group and American Physicians.

Genius that Gave Mallinckrodt Price Target Zero Finds Another Golden Opportunity for Short-Selling

Im ersten Webcast haben Jan von Mallinckrodt, Head of Sustainability bei der Union Investment Real Estate GmbH, und Hermann Horster, Head of Sustainability bei BNP Paribas Real Estate, darüber gesprochen, […]

In 2006 maakte programmamaker Theo Rietveld 12 radio interviews met conservator Ronald Rijkse van de Zeeuwse Bibliotheek in Middelburg. Dit naar aanleiding van de viering van het 150 jarig bestaan van de Wetenschappelijke Bibliotheek in de Zeeuwse hoofdstad. In deel 3 bespreekt Ronald Rijkse de weinige unieke incunabelen uit de collectie. Waaronder een exemplaar waarvan er maar één in de wereld bekend is... Incunabel Een incunabel of wiegendruk is een boek of geschrift dat gezet is met losse letters en gedrukt vóór 1 januari 1501 in Europa. Het woord 'incunabel' is rond 1640 bedacht door de Westfaalse geleerde Bernhard von Mallinckrodt en stamt van het Latijnse 'incunabula' dat windsels (om een baby mee in te bakeren) of luier betekent. Wiegendruk is de letterlijke vertaling daarvan: uit de babytijd van de boekdrukkunst. Het eerste gedrukte boek deed zijn intrede rond 1454, en de periode van de incunabelen heeft dus zo'n kleine halve eeuw geduurd. De incunabeldrukker werkte als ambachtsman meestal om winst te maken. Hij drukte gewoonlijk teksten die goed in de markt lagen, bijvoorbeeld godsdienstig materiaal als bijbels, missalen, theologische commentaren, brevieren en schoolboeken, maar ook 'stichtelijke' teksten, ridderromans, juridische studies en teksten van klassieke schrijvers. In het drukproces werd aanvankelijk gepoogd zo veel mogelijk de handgeschreven teksten te imiteren. Het jaartal 1501 als grens is arbitrair. Het geeft niet direct een omslagpunt in de boekdrukkunst aan, maar is alleen het eerste jaar van de 16e eeuw. Wel maakt de 'incunabelstijl' in de eerste twintig jaar van de zestiende eeuw duidelijk plaats voor de moderne renaissancistische typografie, die begon met de Venetiaanse drukker Aldus Manutius (actief van 1495-1515). Het jaartal 1500 wordt sinds de 17e eeuw algemeen gebruikt als symbolisch eindpunt van de periode waarin het gedrukte boek het manuscript imiteerde. Boeken gedrukt tussen 31 december 1500 en 1540 noemt men postincunabelen. Beide perioden hebben een aantal kenmerken gemeen, die hen in wezen tot één periode maken: • de deelvaardigheden, van zetter tot boekhandelaar, waren nog niet gespecialiseerd: één man kon alle handelingen verrichten • het vak was in opbouw, en er bestonden vele kleine bedrijfjes • er waren nog geen standaardlettertypen ontwikkeld. In de periode tot 1540 waren bovendien Duitsland en Italië belangrijke centra van drukkunst. De rol van belangrijke drukcentra werd na de (post)incunabelperiode overgenomen door Frankrijk, de Nederlanden en Engeland. Toen trad er ook specialisatie op, de bedrijven concentreerden zich en werden grootschaliger, en allengs kregen bepaalde lettertypen internationaal de overhand. Het woord incunabel als term voor drukwerk werd voor het eerst gebruikt in een boek van de Münsterse geestelijke Bernard von Mallinckrodt, De ortu et progressu artis typographicae ("Over de opkomst en ontwikkeling van de kunst der typografie"), gepubliceerd in Keulen in 1639, waarin de zinsnede prima typographicae incunabula ("de vroegste kindertijd van het drukken") voorkomt. Daarin verwijst het woord 'incunabula' naar een periode, niet naar een boek: de periode waarin de typografie nog "een baby was". In 1653 werd die periode vastgelegd zoals wij haar nog gebruiken: Philippe Labbé gebruikte 'incunabula' in zijn Nova bibliotheca librorum manuscriptorum voor het tijdperk tot en met 1500. Pas in de 18e eeuw raakte het woord van toepassing op boeken uit de vroegste periode. Daardoor kon ook de Latijnse nieuwvorming 'incunabulum' ontstaan, dat tegenwoordig niet meer gebruikt wordt.

Welcome to another episode! Dr. David Ballard is an abdominal radiologist serving as an Assistant Professor of Radiology at the Mallinckrodt Institute of Radiology, Washington University St. Louis. He completed his abdominal imaging fellowship at Mallinckrodt and is in his first year as an attending in academic radiology. Dr. Ballard graduated medical school from Louisiana State University Health and completed residency at Mallinckrodt. During radiology residency, he served as chief resident and conducted the annual radiology chief resident survey through the radiology chief resident subgroup of AUR. He has a strong interest in research with over 100 publications and a special interest in 3D printing. He also serves as associate editor for RadioGraphics. The 3D-printing N95 study we mention in Dr. Ballard's interview: https://pubmed.ncbi.nlm.nih.gov/33257256/ Find out more about RadioGraphics here: https://pubs.rsna.org/toc/radiographics/41/6

Key takeaways:Learn about Liam's EPIC comeback journey to successThe VALUE of being able to start from scratchThe art of PRIORITISATION and why this is neededWe can all be INSPIRED by Liam's career journeyAbout Liam Turley:Liam is the CEO and Quality Expert at Trinzo and is based in Galway, Ireland. Liam brings deep executive experience in quality and regulatory strategy and improvements, with a track record of comprehensive quality performance improvement.Liam has worked with the medical device and pharmaceutical industry for over 25 years, including with companies such as Tyco Healthcare, Mallinckrodt, Covidien and Medtronic. Prior to founding Trinzo, Liam was a global vice president of quality assurance with Medtronic. Liam has worked and lived in the United States and the Netherlands and has managed teams globally. Liam has led global initiatives in the area of medical device and combination products.​Liam has expertise in the area of quality remediations and leads companies successfully in resolving notified body major/critical findings, 483s, warning letters and consent decrees. Liam also has extensive MDR expertise and understands the client's needs for a pragmatic approach. He has liaised with multiple notified bodies, competent authorities, the FDA, and ministries of health around the globe.Liam holds a bachelor's degree in microbiology and an MSc in biotechnology, in addition to a postgraduate diploma in pharmaceutical manufacturing.Career inspiration, medtech opportunities, hiring solutions and market insights, all in one place. Find them here.

Dr. ​Steve Roman​o​, ​MD, ​Executive Vice President and Chief Scientific Officer at Mallinckrodt Pharmaceuticals discusses the results of their pivotal Phase 3 STRATA2016 clinical trial of StrataGraft ®, an investigational allogeneic cellularized scaffold product in development for the treatment of adult patients with deep partial-thickness burns. The data was published in "Burns" peer review journal (July 2021). It received FDA approval in July 2021 and can provide burn surgeons with an alternative biologic treatment option for patients with deep partial-thickness burns. #MallinckrodtPharmaceuticals #STRATA2016 Dr. Steven Romano is executive vice president and chief scientific officer at Mallinckrodt Pharmaceuticals. He has executive responsibility for research and development (R&D), medical affairs and regulatory affairs functions, and is a member of Mallinckrodt's executive committee. A board-certified psychiatrist, Dr. Romano has more than 20 years of experience in the pharmaceutical industry. Prior to joining Mallinckrodt, he spent 16 years at Pfizer, Inc. where he held a series of senior medical and R&D roles of increasing responsibility, culminating in his most recent position as SVP, Head, Global Medicines Development, Global Innovative Pharmaceuticals Business. Prior to joining Pfizer, he spent four years at Eli Lilly. After receiving an A.B. in biology from Washington University and a medical degree from the University of Missouri-Columbia, Dr. Romano completed his residency and fellowship at New York Hospital-Cornell Medical Center, continuing on the faculty of the medical school for six additional years.

Jeffrey Prather: Businessman, Author, Actor, Broadcaster, Warrior4518 E Broadway, Tucson, AZ 85749520/241-7690JP@JeffreyPrather.com,WarriorSchool.com,  BujinkanUSA.com. GRIN-X.comTucson business founder since 1990. Second since 1995. Third in 2014. All still going strong. Thought leader, business coach, radio host, life coach, skills teacher.Published author. Specializing in high-stakes strategic analysis, continuity of operations, human terrain, and competitive intelligence preparation of the market place. Martial arts master. World-class firearms instructor.Retired, disabled, Army veteran. Ex-DEA special agent. Former DIA Branch Chief. Chaplain. Adopted orphan. Dad. Husband.Inducted twice into the US Martial Arts Hall of Fame and featured in the US and Japanese martial arts magazines and published in tactical journalsGRIN-X is the intersection for Genetics, Robotics, Information, and Nanotechnology.Futurists predict that in the near-decade GRIN will completely transform the market space.Never before imagined products, therapies, technologies, and markets will emerge.Conventional regulations, traditional financing, and corporate models will be disrupted.BenefitsVia our corporate strategy and competitive intelligence services, we provide emerging technology pathfinders, key stakeholders, and visionary investors, a roadmap to navigate the human and business terrain, to achieve the successful emergence of new medicines, treatments, and technology products.Since 2014 every GRIN-X client exceeded goals. For exampleCancer Prevention Pharmaceuticals-2018In April 2018, UK-based Mallinckrodt had exercised its option to the license agreement and paid CPP $10 million to support the pivotal Phase 3 clinical trial of CPP-1X/sul in patients with the orphan disease familial adenomatous polyposis (FAP).Calimmune-2017Global biotherapeutics leader CSLBehring announced today that it has agreed to acquire Calimmune, Inc., a biotechnology company focused on the development of ex Vivo hematopoietic stem cell (HSC) gene therapy with R&D facilities in Pasadena, California and Sydney, Australia for an upfront payment of  $91 million, with possible milestone payments reaching an eventual total of $416 million.GRIN-X 520-241-7690 8987 E. Tanque Verde Rd St 309-245 Tucson, AZ 8574

Hermann von Mallinckrodt war Katholik aus Überzeugung. Doch als Katholik blieben ihm höchste Ämter verwehrt. Deshalb trieb er den politischen Katholizismus voran und begründete einen jener Diskussionszirkel, aus denen die Zentrumspartei hervorging.

Christliche Parteien im Parlament? Wer die Vorgeschichte von CDU und CSU verstehen will, kommt an Hermann von Mallinckrodt nicht vorbei. Geboren am 5. Februar 1821 in Minden in ein westfälisches Adelsgeschlecht, Katholik wie seine Mutter, und zwar aus tiefster Überzeugung. Jura-Studium, Staatsdienst in verschiedenen deutschen Städten. Autorin: Edda Dammmüller

Hey folks! I'm happy to announce that we've got a rare in-studio guest on this episode! I'm joined by Dr. Phil Pappas, a friend & colleague of mine. Dr. Phil Pappas is the former program director of the Abington Stress Management Center and the Abington A.D.D. Program. He also served as Chief Operating Officer of Abington Behavioral Medicine Associates, which is a mental health clinic at Abington Memorial Hospital in Pennsylvania. Pappas earned his Master's Degree and Doctorate in Nutrition, and has worked for multiple pharmaceutical companies including Mallinckrodt and Bristol Myers Squibb.In this episode, our discussion is focused on the topic of stress and the many ways that it can affect our lives, both positively and negatively. Dr. Pappas provides some insight into some effective methods and techniques to help deal with stress in our everyday lives, as well as some stress alleviating products that you can find perusing the aisles at your local health food store, or at our sponsor site HollyHillVitamins.com.

E11 - President & General Manager at Melnor Inc, Victor Guzman, is an operations leader known for strategic thought leadership, with a positive track record for functional transformations. He has functional expertise in distribution, digital order-to-cash, warehouse operations, transportation. His company, Melnor, was founded in 1946 and specializes in designing and marketing high-quality, hose end watering tools for the home gardening.  He's held senior leader positions at MedPharma Partners, Mallinckrodt (Mallenkrodt) Pharmaceuticals, Getinge, A.T. Kearney, and Honeywell.  Victor has a Masters and Bachelors in Chemical Engineering from MIT. Victor's LinkedIn: https://www.linkedin.com/in/victor-guzman-23449221/ (https://www.linkedin.com/in/victor-guzman-23449221/) Melnor Website: https://melnor.com/ (https://melnor.com/) WHAT YOU WILL DISCOVER IN THIS EPISODE: ●     The time Victor had to cycle in the Pyrenees in Northern Spain to prove himself to his cousins. ●     What's behind Melnor's accelerated business growth during the COVID19 Lockdown. ●     Victor's career path from Mexico City to MIT to the C-Suite. ●     What's is like being one of the 4% of C-Suite leaders who are Latino. ●     What your first step should be in a crisis…it starts with making two lists. ●     What former Honeywell CEO, Dave Cote, taught Victor about dealing with uncertainty. ●     The surprising thing an employee should ask for when they're experiencing burnout. ●     How long should it take for you to get up full speed, when starting a new role.. ●     Why there's no shame in being fired. QUOTES: “The greatest skill you can develop is learning to learn.” RESOURCES: Grant by Ron Chernow: https://www.amazon.com/Grant-Ron-Chernow/dp/159420487X (https://www.amazon.com/Grant-Ron-Chernow/dp/159420487X) Leadership Presence by Justin Patton: https://www.amazon.com/Leadership-Presence-Stand-Shake-World/dp/1732876630 (https://www.amazon.com/Leadership-Presence-Stand-Shake-World/dp/1732876630) ---------------- https://www.benfanning.com/the-ceo-sessions/ (Apply to be on the show) ------------------- https://www.benfanning.com/the-ceo-sessions/ (Connect with Ben:) https://www.linkedin.com/in/benfanning/ (https://www.linkedin.com/in/benfanning/) https://www.instagram.com/benfanning1/ (https://www.instagram.com/benfanning1/) https://twitter.com/BenFanning1 (https://twitter.com/BenFanning1)

Bipartisan opposition to latest White House offer; Gulf of Mexico oil production ramping back up; Mallinckrodt, opioid drug manufacturer, files for bankruptcy

In this Something Extra episode, Executive Vice President and Chief Human Resources Officer at Mallinckrodt, Ian Watkins, shares valuable insight on the beauty of being informed, educated and bold enough to have discussions with people that really do know when you don't.Guest Links:Ian's LinkedInMallinckrodt PharmaceuticalsCredits: Lisa Nichols, Host; Scott Crosby, Executive Producer; Daniel Williams, Recording Engineer; Jenny Heal, Guest Coordinator; Morgan Cochran, Marketing Support

Mallinckrodt ARD LLC v. Seema Verma

Engineering Money, the podcast where some full-time engineers give their two cents on the financial news of the week. What do you get when you cross the fastest dropping US GDP in history with asset inflation? Tim and Joey discuss some major economic trends and the impact on how stocks are trading. Kodak makes the massive pivot to drugs, Vital Farms IPO is bigger than anyone thought, Big Tech® talks to Congress, Mallinckrodt has some wild options action, and all that was just last week... Today's Topics: -Big Tech -Monopolies -EGG IPO outcomes -Inflation, GDP, and that other fun stuff Discord: discord.gg/BDEmaTt Disclaimer: The hosts of Engineering Money are not registered investment, legal, or tax advisors or brokers/dealers. All investment/financial opinions expressed by the hosts of Engineering Money are from personal research and experience and not intended as, and shall not be understood or construed as, financial advice. Although best efforts are made to ensure that all information is accurate and up to date, occasionally, unintended errors and mistakes may occur.

As BC faces its worst ever month for fatal overdoses, Laura Shaver takes Mallinckrodt, the College of Pharmacists, and the Ministry of Health to Court.

In this episode, my guest is Kathy Gann. Kathy is a former MSL director of Mallinckrodt and Syneos Health and we talk about how to prepare a presentation for an MSL interview. Great information so anyone preparing for an interview should check this out.   In this episode: Expect the unexpected Three types of presentation What are the interviewers listening for? How much practice is required to ensure a GOOD presentation? Advice for someone who gets a question they don’t have the answer Interesting interview stories of presentations gone bad Kathy’s advice for aspiring MSL candidates?   Kathy Gann’s LinkedIn

This is the nineteenth episode of "Talking with Authors" by HEC Media and HEC Books. We're a program dedicated to speaking with some of the best selling authors around, covering many different genres.Our author is award winning investigative journalist Ben Westhoff. We spoke with him as he was on tour in September of 2019 with his then brand new book “Fentanyl, Inc.: How Rogue Chemists Are Creating the Deadliest Wave of the Opioid Epidemic” by publisher Grove Atlantic.But after following that thread of information, he found himself tracking down the source of the additives to China, tracing the spread of the synthetic drug throughout the world, and testifying in the halls of the Congress about the manufacture, use, abuse, and effect of fentanyl in the United States. We’ll learn about investigative journalist Ben Westhoff’s deep journey through the illicit drug world and hear some stories about the lives of the businesses and people effected by it on this edition Talking With Authors from HEC Media and HEC Books.Our host and interviewer this time is Brenda Madden.HEC Media is a production company out of St. Louis, Missouri. With the help of independent bookstore Left Bank Books and St. Louis County Library, we are able to sit down with these amazing writers and thought leaders to discuss their work, their inspiration, and what makes them special. You can watch video versions of most of our interviews at hecmedia.org.Host and producer of this episode - Brenda MaddenPhotography - Peter Foggy and Ken CalcaterraAudio - Ben SmithEditor and Graphics - Kerry MarksSupervising Producer - Julie WinkleProduction Support - Christina Chastain and Jane BallewHEC Media Executive Director - Dennis RiggsTalking with Authors Podcast Executive Producer - Christina ChastainPodcast Producer - Rod MilamPodcast Host - Rod MilamYou can follow us on all social media platforms. Just search for "Talking with Authors":Facebook Page: https://www.facebook.com/talkingwithauthorsInstagram: https://www.instagram.com/talkingwithauthorsTwitter: https://twitter.com/TalkingwAuthors

New Decade, New Beginnings! We're excited to announce our WORLDCHANGERS IN TECH PODCAST hosted by Anna Yukiko Bickenbach, geared to present the stories of inspiring digital players and entrepreneurs and how they're impacting the world with their digital solution and/or presence. What is Europe's leading real estate firm doing to meet their own sustainability goals? Find out and tune in now to GERMANTECH's WORLDCHANGERS IN TECH Podcast with Anna Bickenbach! Special guest for this Podcast is Jan von Mallinckrodt, Head of Sustainability at Union Investment Real Estate GmbH.

In the ninth of a multi-part series, Sister Geralyn, SCC, introduces us to Blessed Pauline von Mallinckrodt (June 3, 1817 - April 30 1881). In 1840, she began a kindergarten for children ages 2-6 whose parents were employed in local factories. In 1842, she also established a school for the blind. Thus, education became the primary work of the Congregation of the Sisters of Christian Charity that she founded in 1849. Learn more in this episode of “Musings from a Catholic Evangelist.”

In today’s Our Take read-in, we discuss Commercial Accountable Care Organizations, including updates on programs from UnitedHealthcare, Aetna, Cigna, Humana, and Anthem. To sign up for the weekly email brief, click here. Other briefs include: Harvard Pilgrim Health Care and Tufts Health Plan have signed a definitive agreement to merge. Humana files a lawsuit against Mallinckrodt plc. The FDA has approved Pretomanid Tablets, a game changer in the treatment of treatment-resistant tuberculosis. Centene is expanding its health exchange offerings to ten more states. About Darwin Research Group Darwin Research Group Inc. provides advanced market intelligence and in-depth customer insights to health care executives, with a strategic focus on health care delivery systems and the global shift toward value-based care. Darwin’s client list includes forward-thinking biopharmaceutical and medical device companies, as well as health care providers, private equity, and venture capital firms. The company was founded in 2010 as Darwin Advisory Partners, LLC and is headquartered in Scottsdale, Ariz. with a satellite office in Princeton, N.J.

Opioid drugmakers Insys Therapeutics and Mallinckrodt Pharmaceuticals face millions of dollars in settlement as a consequence of allegedly bribing doctors to prescribe their drugs.

Dr. Sanjeev Bhalla, cardiothoracic radiology section chief at Washington University in St. Louis, discusses teaching, leadership, and vascular imaging.

On Time for Success - Business Owner Moms Edition This week we are interviewing Kim Moos - Cotton Cuts Get to know Kim Kim Moos (pronounced like the hair care product and animal, but spelled like neither) is the Founder and Chief Fabric Enthusiast of Cotton Cuts, an e-commerce subscription provider of premium, precut fabric for quilters. Kim has over 15 years of experience in the corporate world, holding roles of increasing responsibility in R&D, Business Development, Project Management, culminating as the Chief of Staff to the President and CEO at Mallinckrodt. Cotton Cuts is Kim’s first startup venture and she looks forward to leveraging her skill set to pursue her passion. Kim has a degree in Biomedical Engineering from Tulane University and a MBA from Boston University. She is the proud mother of two boys, Lincoln and Dominic and calls St. Louis home.

Talks by Rebekka von Mallinckrodt and Richard Benjamin. Commentary by Catherine Hall. Chaired by Felix Brahm. This event was part of the Contested Histories seminar series 2019 and took place on 7 May 2019 at the German Historical Institute London.

In this week’s episode, John reviews Novartis’ new gene therapy for spinal muscular atrophy, priced at more than $2.1 million. ICER, a nonprofit research institute that evaluates the cost effectiveness of pharmaceuticals, said Novartis’ price is within the upper bound of the organization’s value-based price benchmark range. Briefs include: A broad bipartisan draft health care legislation package containing dozens of provisions was recently released by the Senate Health Committee. Forcing oncology practices to take on downside risk in CMS’ Oncology Care Model in July could result in more than half of them owing the government. UnitedHealth Group pointed to price variations for diagnostic tests as a potential way to reduce overspending. Mallinckrodt plans to spin off its specialty generics business to shareholders. The FDA’s recent approval of Novartis’ Piqray (alpelisib). FDA clears a new wearable device to treat migraine. Biogen is scrapping its investigational treatment for Alzheimer’s disease, and is canceling its Phase III ENGAGE and EMERGE clinical trials. About Darwin Research Group Darwin Research Group Inc. provides advanced market intelligence and in-depth customer insights to health care executives, with a strategic focus on health care delivery systems and the global shift toward value-based care. Darwin’s client list includes forward-thinking biopharmaceutical and medical device companies, as well as health care providers, private equity, and venture capital firms. The company was founded in 2010 as Darwin Advisory Partners, LLC and is headquartered in Scottsdale, Ariz. with a satellite office in Princeton, N.J.

The team takes a look back at the past week and previews what's to come in the week ahead, and does a review of volatile credits following Q1 results including Avon, Mallinckrodt and Monitronics. If you are not a Reorg subscriber, request access here: go.reorg-research.com/Podcast-Trial

Mallinckrodt spinoff sparks covenant considerations and Tronox, Chemours comparisons by Debtwire Radio

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  Introducing Minnie von Mallinckrodt-Grant – Minnie helps people who want to make an impact in the world to get their message out there. She teaches us that when you follow your passion, you can choose the life that you want. She does this through mixing her experience as a TEDx curator and speaker coach with her background in performing arts, sales, and marketing. She does this because she loves it and it gives her a buzz to see her clients succeed and take some risks. TOPICS DISCUSSED IN THIS PODCAST EPISODE: (03:01) What is TED? (06:37) How to get onto TED (10:46) How to get approved (18:48) How many speakers are allowed (22:29) About curating TED talks (26:44) Getting your message across to young entrepreneurs in a talk on stage (32:06) Taking the pressure off children HEAR MORE ABOUT MINNIE VON MALLINCKRODT-GRANT: Minnie is a TEDx Coach and Marketing Strategist who helps her clients do 3 things; develop TED worthy presentations, deliver their talks authentically with confidence and develop a game plan to get a TEDx talk. She loves working with change makers, leaders and trailblazers. When she’s not doing what she loves, she enjoys messing about and having fun with her family and friends. She believes that true leadership comes from knowing thyself, being brave to be visible in standing up for what you believe in and doing what you believe is right regardless of what others think. FAVOURITE QUOTES TO SHARE WITH THE WORLD I’m Brian and so is my wife – Monty Python If you follow the herd you will tread in a lot of shit ONE BOOK YOU SHOULD READ The 4 Agreements – powerful realizations yet simple to follow CONNECT WITH MINNIE Website Facebook Linkedin Twitter Instagram CONNECT WITH SASHKA Facebook Instagram Pinterest Twitter LinkedIn Want to be a guest on the podcast? Apply to be featured on the No Name Brand Podcast here. SUBSCRIBE ON     

Learn more about which bonds are on the move with this weekly podcast. Finally we see the AUD fall against the USD as our experts predicted. This has led to some exiting USD positions, others switching into better credits or repatriating funds home. Companies mentioned include: Next Generation, AroundTown, Talen, Mallinckrodt, Hertz, IAMGOLD and Dean Foods. See the transcript below.

Etwa 100 Kinder und Jugendliche leben heute im Kinderheim Pauline von Mallinckrodt in Siegburg. Sie sind übergangsweise da, weil ihre Eltern gerade nicht für sie sorgen können. Betreut werden sie nicht nur von Erzieherinnen und Erziehern. Auch der Orden der Schwestern der Christlichen Liebe begleitet die Kinder – und das schon seit Gründung des Hauses. Johanna Risse berichtet. Moderation: Irene Groß.

For eight years, I lived two blocks from Latty Avenue, 2000 yards from the Latty Avenue Waste Site. The HBO feature, Atomic Wasteland, highlights this site and it's history. My essay gives facts, names corporations and the US Government agencies responsible for dumping, covering up and deflecting blame for polluting North St. Louis County and surrounding areas with radioactive waste. If you have lived, worked or driven through this area, you are affected.

For eight years, I lived two blocks from Latty Avenue, 2000 yards from the Latty Avenue Waste Site. The HBO feature, Atomic Wasteland, highlights this site and it's history. My essay gives facts, names corporations and the US Government agencies responsible for dumping, covering up and deflecting blame for polluting North St. Louis County and surrounding areas with radioactive waste. If you have lived, worked or driven through this area, you are affected.

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var lhnAccountN=16789; var lhnButtonN = 17; var lhnInviteEnabled = 1; var lhnInviteChime = 0; var lhnWindowN = 0; var lhnDepartmentN = 0; var lhnCustomInvitation = ''; var lhnCustom1 = ''; var lhnCustom2 = ''; var lhnCustom3 = ''; var lhnTrackingEnabled = 't'; var lhnVersion = 5.3; var lhnJsHost = (("https:" == document.location.protocol) ? "https://" : "http://"); var lhnScriptSrc = lhnJsHost + 'www.livehelpnow.net/lhn/scripts/livehelpnow.aspx?lhnid=' + lhnAccountN + '&iv=' + lhnInviteEnabled + '&d=' + lhnDepartmentN + '&ver=' + lhnVersion + '&rnd=' + Math.random(); var lhnScript = document.createElement("script"); lhnScript.type = "text/javascript";lhnScript.src = lhnScriptSrc; if (window.addEventListener) { window.addEventListener('load', function () { document.getElementById('lhnContainer').appendChild(lhnScript); }, false); } else if (window.attachEvent) { window.attachEvent('onload', function () { document.getElementById('lhnContainer').appendChild(lhnScript); }); } What Do You Get When Legal Drug Dealers Peddle "Heroin-in-a-Pill" to it's "Clientele"? Interactive GraphicsJaclyn Kinkade, a 23-year-old doctor's-office receptionist and occasional model, was a casualty of America's No. 1 drug menace when she overdosed and died, alone, in a tumbledown clapboard house in Dunnellon, Fla. The drugs that killed her didn't come from the Colombian jungles or an Afghan poppy field. Two of the three drugs found in her system were sold to Ms. Kinkade, legally, at Walgreen Co. and CVS Caremark shops, the two biggest U.S. pharmacies. Both prescription drugs found in her body were made in the U.S.—the oxycodone in Elizabeth, N.J., by a company being acquired by generic-drug giant Watson Pharmaceuticals Inc., and the methadone in Hobart, N.Y., by Covidien Ltd., another major manufacturer. Every stage of their distribution was government-regulated. In addition, Ms. Kinkade had small amounts of methamphetamine in her system when she died.The U.S. spends about $15 billion a year fighting illegal drugs, often on foreign soil. But America's deadliest drug epidemic begins and ends at home. More than 15,000 Americans now die annually after overdosing on prescription painkillers called opioids, according to the Centers for Disease Control and Prevention—more than from heroin, cocaine and all other illegal drugs combined. Rising opioid abuse means that drug overdoses are now the single largest cause of accidental death in America. They surpassed traffic accidents in 2009, the most recent CDC data available. Paradoxically, the legality of prescription painkillers makes their abuse harder to tackle. There is no Pablo Escobar to capture or kill. Authorities must contend with an influential lobby of industry representatives and doctors who argue against more restrictions, saying they would harm legitimate patients. And lawmakers have been reluctant to have the federal government track Americans' prescriptions, leaving states to piece together a patchy, fragmented response.Ms. Kinkade's final days, and the path of the drugs that killed her, were reconstructed from medical and prescription records, police files and interviews. Many records were assembled by Ms. Kinkade's father and stepmother.Shuffling through the documents at their living-room table, Bruce Kinkade, a garage-door salesman, and his wife, Ann, said they don't wish to absolve their daughter of responsibility. "We're not naive and want to say she was a perfect angel," said Ann Kinkade, Jaclyn's stepmother. Tracing the Path of Prescription PainkillersJaclyn Kinkade A family photo of Jaclyn Kinkade as a child with a composite of the prescription records.But the Kinkades say the companies and licensed professionals that supplied her with the drugs must also bear some responsibility. "Jackie didn't wake up one day and say, 'Hey, I'm going to be a drug addict today,'" Ann Kinkade said. "Jackie pretty much got sent there by a doctor, got hooked and continued to go back."There are few easy villains in prescription drug abuse. Companies, physicians and addicts alike are all pieces in a complex puzzle. For some time, regulators have been cracking down on doctors who prescribe to addicts for profit. Now, federal and state officials are starting to move up the supply chain to pursue pharmacies and distributors. On Sept. 12, the Drug Enforcement Administration revoked the licenses of two Florida CVS stores, which it claims sold excessive amounts of oxycodone without ensuring the pills weren't diverted to the black market. CVS is fighting the DEA's order in administrative and federal courts.Two days later, the agency served Walgreen with a suspension order halting sales of controlled substances from its Jupiter, Fla., distribution center, calling it an "imminent threat to public safety." The DEA's regulatory action alleges that the facility—the state's largest oxycodone distributor—"failed to maintain effective controls'' of its narcotic painkillers. Walgreen said it is working with regulators and has tightened its procedures. CVS said it was committed to working with regulators "to reduce prescription drug abuse and diversion while ensuring access to appropriate, effective pain medication for our patients who need them."Participants in the drug-supply chain acknowledge the problems but point to others as the weak link. Doctors involved say pharmacies should be able to tell if patients are secretly using several physicians to obtain more drugs. Druggists say they can't second-guess a valid prescription. Manufacturers and distributors say they are simply delivering products ordered by health-care professionals.What makes this drug scourge different from previous ones, such as heroin in the 1970s and cocaine in the 1980s, is that everyone in the distribution chain is identifiable. The DEA itself controls the supply spigot by setting drug companies' production quotas for opioids like oxycodone and hydrocodone. For years, opioids were reserved mainly for cancer or terminally ill patients because of fears over their safety and addictiveness. But over the past 15 years, many doctors have come to view them as an essential tool to manage chronic pain. Around the same time, drug makers began marketing patented, time-release formulations of the drugs, making it a lucrative category.Today, a growing number of doctors say the pendulum has swung too far, with powerful narcotics being dispensed for even relatively minor complaints. Last year, pharmacies dispensed more than $9 billion in prescription opioid painkillers, more than twice the amount a decade earlier, according to IMS Health, a research firm. The number of prescriptions has risen fourfold. The generic version of Vicodin, a blend of hydrocodone and acetaminophen, is now the most prescribed drug in the country.Opioids come from the same narcotics family as heroin and can produce similar addictions, researchers say. "We're basically talking about heroin pills," said Andrew Kolodny, chairman of the psychiatry department at Maimonides Medical Center in New York.Studies show that opioid addicts come from a surprisingly broad swath of the population: the middle-age, the elderly and, increasingly, young adults. Many U.S. veterans returning from Iraq and Afghanistan with physical and mental injuries are also becoming dependent on prescription painkillers, researchers say. In recent decades, researchers have come to view addiction as a disease, rather than just a personal failing. Some people are more predisposed to becoming addicted because of heredity, experience and other factors that have yet to be fully understood. But some drugs are simply more addictive than others.Jaclyn Kinkade Before She Began Taking Drugs.New research suggests that drugs like opioids cause long-lasting changes to the brain, rewiring some areas to crave more drugs while simultaneously damaging the parts that can control those cravings. The drugs can damage the brain's ability to feel pleasure, so regular users eventually need to take them not to get high or help with pain, but just to feel normal. Avoiding unpleasant withdrawal symptoms end up conditioning many drug users' daily lives. One of the most confounding aspects of this latest epidemic is that it blurs the lines between legal and illegal drug use. Some people first take drugs from their family medicine cabinets to get high, then go to doctors to get more. Others are originally prescribed the pills for legitimate reasons, then buy them on the street once they're hooked.Many, such as Ms. Kinkade, end up mixing legal and illegal drugs in ways that can prove lethal.Ms. Kinkade was a lively, talkative woman with blond hair, a fear of caterpillars and a pit-bull terrier, Bentley, that traveled everywhere with her. She was first prescribed an opioid on Oct. 27, 2006, by the doctor who employed her as a receptionist, prescription records show. According to medical records and an entry from her diary, she had been suffering back and neck pain. Thomas Suits, her employer, prescribed 20 pills of Endocet, a drug containing oxycodone. "I'd never taken opioids before," Ms. Kinkade wrote in a diary entry. "But I started the med routine and OMG I felt no pain."Jaclyn Kinkade on vacation when she was 21 years old. She died of an accidental drug overdose about two years later, at age 23.Dr. Suits didn't recall prescribing the medication, said his wife, Irene Machel, a doctor who also works at the clinic. She declined to discuss the matter further. Endo Health Solutions, which made the pills, declined to comment on Ms. Kinkade. "These types of stories are tragic and we obviously take them seriously," said Endo spokesman Blaine Davis. "Our responsibility, as a company that is very dedicated to the field of pain management, is to educate both physicians and patients about appropriate use."Soon Ms. Kinkade was seeking more drugs. On Jan. 5, 2007, she saw Bruce Kammerman, a family practitioner at a clinic in Stuart, Fla., and came away with a generic blend of oxycodone and acetaminophen. A scan taken a month later showed no problems with her spine, according to the medical report. Through his lawyer, Dr. Kammerman declined to say why he wrote the prescription. "That's a sad case," said his attorney, Lance Richard. "Maybe she didn't have justifiable pain but she certainly came in and made complaints about it. At some point the doctor just has to go on the patient's word."Dr. Kammerman was arrested in July at a pain clinic in Vero Beach, Fla., charged with drug trafficking, racketeering and illegally selling controlled substances. The DEA said in a news conference he was prescribing an average of 1,700 oxycodone tablets a day. Dr. Kammerman's lawyer said his client has done nothing wrong and pleaded not guilty.Jaclyn Kinkade In a Mug Shot on May 10, 2010, Two Months Before Her Death.Ms. Kinkade broke up with her boyfriend. She began missing work. One day she was found curled up under her desk, crying. "She always used to be clean-cut, nice makeup," said Susan Cochran, a former colleague. Then "she would come in in sweatpants and it was like: 'Who is this person?'"Ms. Kinkade changed jobs to work at a radiologist's office. There, she had two other scans, in April and July 2008. Neither showed significant spine problems, according to the medical reports. Ms. Kinkade started seeking clinics that asked fewer questions. "Family practitioners hate writing narcotics," she wrote in her diary. "Nowadays—I'll just go str8 to pain docs."During that period, she was prescribed large amounts of oxycodone, her records show, combined with antianxiety drugs and powerful muscle relaxants. Her parents grew increasingly alarmed. "Sometimes you'd be having a conversation with her and her head would just drop," Mr. Kinkade said. "And she'd say: 'Oh, I'm just tired; I was out late.'"After reviewing her records, he said, "We estimated that at one point she was taking 13.4 pills per day, for nothing wrong with her."In May 2009, Mr. Kinkade and his wife asked a judge to have their daughter forcibly admitted to drug treatment under a Florida law. Their request was initially denied because she wasn't a minor. Angered by their efforts, Ms. Kinkade moved out of their home and drove across the state to her biological mother's house. She crashed her car and was found wandering along the highway in a drug-induced daze, her parents said, searching for her pills. Legal records show she was arrested several times for minor crimes such as possessing controlled drugs without a prescription and shoplifting small items, including makeup and cake topping. In each case, she was released and the charges dropped. She started visiting a pain clinic in Tampa called Doctors Rx Us, where she was prescribed oxycodone, methadone, alprazolam and gabapentin, an antiseizure medication, according to records her parents collected. Housed in a rundown strip mall, the clinic today is called Palm Medical Group after a name change in 2011, according to its state records. Ms. Kinkade was prescribed the drugs by two physicians at Doctors Rx Us: Richard Smith and William Crumbley. Dr. Crumbley was arrested in December and charged with operating a nonregistered pain clinic at another location. He has pleaded not guilty.Dr. Smith and the clinic declined repeated interview requests. A lawyer for Dr. Crumbley said he was innocent of any wrongdoing. On May 3, 2010, Ms. Kinkade stopped at a CVS in Crystal River, Fla., and picked up a prescription written by Dr. Smith for 90 tablets of 10mg methadone, along with 90 tablets of alprazolam, an antianxiety drug. "Jaclyn Kinkade's death is a terrible tragedy that highlights the need for a comprehensive national effort to prevent prescription drug abuse," CVS said in a statement.Information provided by the manufacturer suggests that the methadone dispensed to Ms. Kinkade was likely supplied to CVS by Cardinal Health Inc. Cardinal was the only distributor to have sold that particular drug to that CVS branch during that period, according to the manufacturer's records. CVS and Cardinal declined to comment. Last year, the DEA launched a probe of the Florida-based operations of Cardinal Health and CVS Caremark. The agency alleged they dispensed "extremely large amounts" of oxycodone with signs that the drugs were "diverted from legitimate channels." CVS said it has "responded to the DEA's concerns, including implementing enhancements to our policies and procedures for filling controlled substance prescriptions." Cardinal settled with the DEA in May, agreeing to suspend sales for two years at one of its key distribution facilities in Lakeland, Fla. The methadone Ms. Kinkade picked up at the end of her life was made in Hobart, N.Y., by Mallinckrodt, a unit of health-care giant Covidien. "Any death from abuse or misuse of prescription drugs is tragic," Covidien said. "That's why we believe that, as a nation, ending the abuse, diversion and misuse of powerful pain medications is necessary to ensure adequate treatment of pain and access to that treatment for legitimate pain patients."On May 10, 2010, Ms. Kinkade was stopped by police in Levy County, Fla., for having an expired registration. A drug-sniffing dog reacted to her car and she was arrested for possessing a generic form of Xanax without the correct prescription. This time, her parents let her sit in jail for a couple of weeks while they organized a place for her in a rehabilitation program. They bailed her out May 25 and enrolled her in drug treatment.Over the next month, Ms. Kinkade went to the treatment program during the day and seemed to improve, her parents said. Then, the evening of June 24, she climbed out the window at her parents' house. A few days later, on the other side of Florida, she met up with a boyfriend, according to a statement he later gave police. She returned to Doctors Rx Us, where Dr. Smith wrote a prescription for 90 tablets of 30mg oxycodone, according to prescription records. It would be her last. The next day, Ms. Kinkade filled the prescription at a Walgreens in Beverly Hills, Fla. The oxycodone would have come from Walgreen's Jupiter, Fla., distribution center, a company spokesman said. On Sept. 14, the DEA barred that facility from selling controlled substances, alleging that it failed to maintain effective controls to stop large amounts of oxycodone from reaching the black market. "When [companies] choose to look the other way, patients suffer and drug dealers prosper," Mark Trouville, the DEA special agent in charge, said at the time. Walgreen said in a statement it is cooperating with the DEA. The oxycodone came from the New Jersey plant of Actavis, a Swiss pharmaceutical company. In April, Actavis was bought by Watson Pharmaceutical in a $5.8 billion deal awaiting regulatory approval. An Actavis spokesman described Ms. Kinkade's situation as a "tragic occurrence" and called for discussion on "how to prevent such cases in the future." A Watson spokesman cautioned against action that would make it harder to treat legitimate patients. He said the company supported educating patients about the drugs' proper use.The morning of July 4, Ms. Kinkade's boyfriend found her sitting cross-legged and slumped in his room at a white, low-slung house tucked behind a trailer park. The medical examiner said she died from a drug cocktail including oxycodone, methadone and methamphetamine.Ms. Kinkade's physical decline made such an impression on the detective who investigated the case that, two years later, he still recalls the scene. In the living room, he noticed a poster of Ms. Kinkade modeling for a biker magazine."Wow, she's a beautiful young lady," Detective Matthew Taylor remembered thinking. "When I actually saw her, it was as different as night and day." 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