Willing abstinence from some, or reduced consumption of, food, drink or both, for a period of time
POPULARITY
Categories
“Diet culture loves to exaggerate grains of truth and turn them into something extremely blown out of proportion.”Fasting is everywhere right now, but what does the research actually say? In this episode, I break down the claims, benefits, and red flags surrounding fasting, including why short-term results don't always tell the whole story. We'll also explore how fasting can impact your relationship with food, why it may function as another form of dieting, and the important difference between restrictive fasting protocols and meal spacing that may support certain health needs.What You'll Learn:What the current research does (and doesn't) tell us about fastingWhy short-term health improvements don't always translate into long-term resultsHow fasting can affect food noise, binge eating risk, and your relationship with foodWhy many forms of fasting function as another form of calorie restrictionWhen meal spacing may support gut health and how it differs from popular fasting trendsWhy the best approach to nutrition depends on your unique needs, health history, and relationship with foodResources:Grab the Hunger & Fullness Scale Guide at DietCultureRebel.com/hungerfullnessscale and take your next step toward building trust with your body and food.Episode 207: What Diet Culture Gets Wrong About Gut Healthy (with Dr. Heather Finley)Connect with me over on Instagram at @diet.culture.rebel.Struggling with food, but not sure where to start?You don't have to feel 100% ready to get support. If you're tired of obsessing over food or feeling stuck in the diet cycle, my team of Registered Dietitians is here to help. We offer one-on-one nutrition counseling—and we accept insurance! Spots are limited, so head to https://dietculturerebel.com/insurance to see if we're covered in your state and learn how to get started.
What if one simple nutrition strategy could support healthy aging, improve metabolic health, boost energy, and even help your skin look better? In this episode of Insights from the Couch, Laura sits down with Renee Fitton, VP of Growth at Prolon and a leading voice in nutrition and longevity science, to unpack the research behind fasting and the fasting mimicking diet.We explore the growing confusion around nutrition in midlife, from protein overload to supplement fatigue, and discuss a more balanced approach to health, longevity, and wellness. Renee shares how fasting mimicking works, why autophagy matters, and what the science says about supporting your body through midlife and beyond. If you've been curious about fasting but overwhelmed by conflicting advice, this conversation is a great place to start.Episode Highlights[0:03] - Laura introduces Renee Fitton and the science-backed world of fasting and longevity[2:13] - Why so many midlife women feel overwhelmed by health and nutrition advice[2:52] - What Prolon is and how a fasting mimicking diet works[6:30] - The current protein craze: what's helpful, what's excessive, and what longevity research suggests[13:36] - Understanding autophagy and the body's natural repair and rejuvenation process[15:44] - The surprising health benefits linked to fasting mimicking, from metabolic markers to skin health[17:28] - How long the benefits last and why fasting may improve your relationship with food[19:30] - Renee shares her personal experience completing multiple fasting mimicking cycles[22:19] - What you actually eat during a Prolon fast and how manageable it feels day-to-day[24:02] - The real-world changes Renee notices in energy, sleep, skin, and mental clarity[27:01] - Who should avoid fasting mimicking and important safety considerations[28:24] - Fasting, cancer recovery research, and resources for survivors[30:18] - Why a gentle 12-hour circadian fast may be more effective than extreme intermittent fasting[32:35] - The hidden impact of skipping breakfast and relying on coffee[34:03] - Why fasting mimicking can be especially beneficial for women in midlife[37:43] - Where to learn more about Prolon and how to get startedLinks & ResourcesProlon Life: https://prolonlife.comRenee Fitton on Instagram: https://www.instagram.com/fittonnutritionRenee Fitton on LinkedIn: https://www.linkedin.com/in/reneefitton/If today's discussion resonated with you or sparked curiosity, please rate, follow, and share "Insights from the Couch" with others. Your support helps us reach more people and continue providing valuable insights. Here's to finding our purposes and living a life full of meaning and joy. Stay tuned for more!Ever stayed quiet to keep the peace and felt yourself disappear? The Cost of Quiet is for anyone who avoids conflict and pays the price. Reclaim your voice, strengthen your relationships, and experience real peace. Order your copy and join the movement: https://www.colettejanefehr.com/new-book
Fasting is powerful—but fasting alone isn't always enough. Episode #262
Learn about the Healing Power of Prolonged Fasting: HEREWhat if one of the most studied alternative cancer therapies in the world was used across Europe and South America, yet still out of reach in the United States? Dr. Katie Deming sits down with Dr. Nasha Winters, a globally recognized authority in integrative oncology and co-author of Mistletoe and the Emerging Future of Integrative Oncology. Dr. Winters has trained hundreds of physicians in mistletoe therapy and has also used it herself.Together, they unpack a plant most people only know from the holidays and explore why injectable mistletoe has been used in cancer care since 1917. You'll hear how mistletoe may work on multiple levels: supporting the immune system, affecting the tumor environment, and helping the body's terrain during and after treatment.If you've ever felt rushed into decisions based on a scan, this episode is especially important. Dr. Winters explains pseudoprogression, a phenomenon where things may appear worse on imaging before they improve, and why timing scans too soon can lead to fear-driven decisions based on misleading information.Chapters:00:06:39 - The Most Studied Alternative Cancer Therapy00:08:18 - Why the U.S. Still Requires New Trials00:09:34 - The Patient Who Changed Dr. Winters' Path00:12:43 - How Mistletoe Works in the Body00:14:02 - Waking Up the Immune System00:16:28 - Quality of Life During Cancer Treatment00:18:42 - Mistletoe, Fasting, and Metabolic Support00:21:37 - Why Terrain Matters More Than Tumor Kill00:27:42 - Why Practitioner Training Matters00:30:01 - The Scan Mistake That Can Change Everything00:34:17 - When to Image During Mistletoe Therapy00:37:06 - When Healing Looks Worse Before Better00:41:00 - Who Should Be Careful With Mistletoe00:42:54 - Why Fasting and Mistletoe Work TogetherMost relevant support from the transcript: the episode moves from mistletoe's history and use since 1917, into mechanism and terrain, then closes with pseudoprogression, scan timing, and who should use caution. Stay until the end, because Dr. Winters shares how one patient first pushed her to explore mistletoe therapy, and how that moment opened the door to decades of clinical experience with a treatment most Americans still never hear about.Press play to learn why your body may be far more capable of healing than you've been told.Connect with Dr. Nasha: https://drnasha.com/Pick up a copy: Mistletoe and the Emerging Future of Integrative OncologyJoin Dr. Katie's 3-Day Guided Fast, for expert support, daily live calls, and a community to fast alongside: Sign-Up Follow Dr. Katie Deming on InstagramWatch on YoutubeDISCLAIMER: The Born to Heal Podcast is intended for informational purposes only and is not a substitute for seeking professional medical advice, diagnosis, or treatment. Individual medical histories are unique; therefore, this episode should not be used to diagnose, treat, cure, or prevent any disease without consulting your healthcare provider.A thought-provoking podcast explores cancer through the lens of holistic medicine and functional medicine, discussing causes of cancer, metabolic health, and unconventional approaches like water fasting, fasting and autophagy, and detox, while weighing fasting benefits against chemo side effects and radiation side effects, sharing stories of a cancer survivor navigating chemotherapy, natural medicine, holistic healing, and even spiritual healing on the path toward cancer remission and holistic health.
Send us Fan MailWhat happens to your spirit when you fast?In this episode of The Faith of the Fathers, Karl Gessler sits down with Joe Roraff to discuss one of the most powerful and often neglected spiritual disciplines in the Christian life: fasting.Joe shares the remarkable story of how his father's 21-day fast became a catalyst for his own spiritual transformation and pursuit of God. Together, Karl and Joe explore the purpose of fasting, common misconceptions surrounding it, and why so many believers struggle to make it a regular part of their walk with Christ.The conversation covers practical challenges, hearing the voice of the Holy Spirit, spiritual sensitivity, breakthrough, and the cumulative impact of simple acts of obedience over time. Rather than viewing fasting as a religious obligation, Karl and Joe present it as an invitation to draw closer to God and create space for Him to work more deeply in our lives.Whether you are considering your first fast or have practiced fasting for years, this conversation will encourage you to seek God with greater hunger and expectation.In This Episode What fasting actually does to your spirit Joe's testimony of his father's 21-day fast Common fears and misconceptions about fasting Learning to hear the voice of the Holy Spirit The connection between fasting and spiritual breakthrough Why spiritual disciplines have a cumulative effect Practical encouragement for believers who want to begin fastingThank you for listening to The Faith of the Fathers.If this episode encouraged you, please consider subscribing, sharing it with a friend, and leaving a review. For more teachings, worship music, testimonies, and ministry resources, follow Karl Gessler and The Faith of the Fathers @ karlgessler.comSupport the show❤️ SHOW YOUR SUPPORT - LINKS BELOW...➡️ Email me: https://www.karlgessler.com/deliverance➡️ DONATE ➡️ Join our team!https://www.givesendgo.com/karlgessle... / karlgessler ...
What if the thing controlling your life is the very thing God wants to use to draw you closer to Him?This week, Pastor Gregg continues our Unhurried series by exploring the spiritual practice of fasting and why it has been a vital rhythm for followers of Jesus throughout history. Looking at Jesus' temptation in the wilderness, we discover how fasting trains us to say no to our desires, strengthens us for spiritual battle, and sharpens our focus on God. In this message, we learn that fasting isn't about earning God's favor—it's about creating space for deeper dependence on Him and learning to hunger for God more than anything else.If you've ever felt distracted, spiritually stagnant, or controlled by desires you struggle to overcome — this message is for you.We hope that you enjoy this series! Subscribe if you haven't already to stay up to date with what we've got going on here at Creekside Church!Insta: creeksidechurchnpCheck out our website! https://creekside.church
What if the food you eat could make you smarter, sharper, and more energized?In Episode 290 of the Moonshots Podcast, Mike and Mark dive into The Bulletproof Diet by biohacker and entrepreneur Dave Asprey. Together they challenge common diet myths, explore the science behind fasting, discuss the rise of Bulletproof Coffee, and examine how inflammation impacts performance, energy, and longevity.This episode is not about chasing the perfect diet. It's about discovering how nutrition can become a practical tool for better thinking, deeper focus, and sustainable wellbeing. Whether you're curious about intermittent fasting, optimizing your morning routine, or simply improving your relationship with food, this conversation offers practical insights you can start applying immediately.Buy The Bulletproof Diet:https://geni.us/FQVMdjDLearn more:https://www.moonshots.ioYouTube Channel:https://www.youtube.com/channel/UCGqs7VdIufLYNWnzZYuVaTAKey ThemesThe role of willpower in sustainable health habitsCommon myths and misconceptions about dietingBiohacking as a framework for personal optimizationThe impact of inflammation on health and performanceIntermittent fasting and metabolic flexibilityBulletproof Coffee and cognitive performancePersonalized nutrition versus one-size-fits-all dietsHealth as a vehicle for achievement and fulfillmentConcepts & BreakthroughsChallenging Diet MythsThe episode opens by examining some of the most persistent misconceptions about nutrition. Ideas such as "fat makes you fat," "skipping breakfast is unhealthy," or "healthy eating is always expensive" often survive because they are simple, not because they are accurate.Dave Asprey encourages listeners to question assumptions and focus on experimentation. The most effective dietary strategy is often the one that aligns with your unique biology, lifestyle, and goals.Biohacking Your EnergyAt the heart of Asprey's philosophy is biohacking—the practice of systematically improving physical and mental performance through observation and experimentation.Rather than accepting fatigue, brain fog, or poor energy as inevitable, biohacking asks a simple question:What small change could improve how I feel today?This mindset turns health into an ongoing process of discovery rather than a rigid set of rules.The Inflammation ConnectionOne of the most important insights discussed is the relationship between diet and inflammation.Many modern foods contribute to chronic low-grade inflammation, which can manifest as fatigue, digestive discomfort, reduced cognitive performance, and long-term health challenges.By focusing on higher-quality foods and reducing inflammatory triggers, listeners can create an environment where their bodies and minds perform more effectively.Fasting for FocusFasting is often viewed solely as a weight-loss tool, but the episode explores its broader benefits.Strategic fasting may help:Improve mental clarityIncrease focusEnhance metabolic flexibilityReduce reliance on constant food intakeMike and Mark discuss how many people discover that delaying breakfast can provide a surprising boost in productivity and concentration during the morning hours.Bulletproof CoffeeOne of Dave Asprey's most recognizable contributions is Bulletproof Coffee—a combination of coffee, healthy fats, and MCT oil designed to support sustained energy.The concept challenges traditional breakfast habits by providing fuel without triggering the energy crashes often associated with carbohydrate-heavy meals.Whether listeners adopt the practice or not, the larger lesson is to think intentionally about how morning nutrition affects cognitive performance.Health as a Means to an EndPerhaps the most powerful idea in the episode is that health is not the destination.Health is the vehicle.The purpose of eating well, sleeping better, exercising, and managing energy is not simply to achieve perfect health metrics.
Is it perimenopause, or are you just finally fed up with the world? Honestly, it might be both.In this listener Q&A, I'm answering the questions so many of you have been sending me, and they're the kind that probably sound familiar. We start with mood, because so many of us feel more irritable, less patient, and a lot less willing to tolerate things we used to put up with. I'll walk you through what's happening with your hormones and neurotransmitters, and why your reasons for feeling done are still valid even when biology is part of the picture.From there, I tackle the big one: the belief that decades of dieting have "broken" your metabolism. I talk about what's really driving the lose-it-gain-it cycle, why intermittent fasting leaves so many women feeling awful, and the food guilt that shows up over something as ordinary as two slices of bread.I also answer a question that pulled at my heart, from a parent who overheard their daughter say she needed to "walk off" her dessert. If you've ever heard your own voice come out of someone you love, this one is for you.If any of this lands, I'd love to keep the conversation going. You'll find a link in the show notes to send me your questions for the next Q&A, and if you're ready for support:Book a callBecome a Feaster Send me your question for a future Q&A episode! Related episodes you'll love:#132: Why You Need to Put Capacity, Self-Compassion & Self-Care on the Menu#147: Why You Keep Starting Over Every Monday#136: Health vs. Weight: Debunking the Biggest Wellness Myth with Val Schonberg, RDWhat did you think of this episode? Click here and let me know!
Try TrueDark glasses: https://truedark.comTry Danger Coffee: https://dangercoffee.com/Try Suppgrade Labs: https://shopsuppgradelabs.com/Over the last 15 years, I've built companies and spent millions testing what actually upgrades human performance, and I can tell you that mental fatigue has absolutely nothing to do with willpower. In this video, I break down the exact neurochemistry of deep focus. When your brain runs out of dopamine, norepinephrine, and acetylcholine, or gets bogged down by oxidative stress, your executive function collapses. The pharmaceutical industry wants you hooked on expensive stimulants that only treat the symptoms, but the real biological fix is a common antioxidant: Vitamin C.I explain how your brain hoards Vitamin C at levels 100 times higher than your blood, how to bypass the blood-brain barrier using SVCT2 transporters, and why eating sugar before you take it completely blocks its absorption. You'll also learn the exact biohacking stack—including NAC, CoQ10, PQQ, and L-theanine—you need to recycle this molecule, protect your mitochondria, and maintain effortless, razor-sharp focus all day long.Thank you to our sponsors!-KILLSwitch | If you're ready for the best sleep of your life, order now at https://www.switchsupplements.com/and use code DAVE for 20% off-Viome | Check it out at viome.com and use code 10DAVE for 10% off. It's time to stop guessing and start knowing your body.-iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVETimestamps:00:00 – Trailer00:21 – Focus Is Biology01:53 – Brain Chemistry Explained05:33 – Vitamin C Revealed07:09 – How to Dose08:18 – Absorption Barriers09:31 – Optimize Uptake10:00 – Oxidative Stress Problem11:00 – Stack for Deeper FocusConnect with Dave Asprey!Website: https://daveasprey.comTikTok: https://www.tiktok.com/@daveaspreyofficialInstagram: https://www.instagram.com/dave.asprey/Facebook: https://www.facebook.com/Daveaspreyofficial/X: https://x.com/daveaspreyYouTube: https://www.youtube.com/c/daveaspreybprThe Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/Danger Coffee: https://dangercoffee.com/DAVE15Dave Asprey's BEYOND Conference: https://beyondconference.com/Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15Upgrade Labs: https://upgradelabs.com40 Years of Zen: https://40yearsofzen.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Brandon Steele | 06.14.26 | ethoschurch.org
We all want to be like someone else—but what if the One we were made to become like is Jesus himself? Kicking off our new summer series, Living Like Jesus, Pastor Jared Stevens looks at the spiritual disciplines Jesus practiced throughout the book of Luke, starting with one many of us tend to avoid: fasting. Walking through Luke 4:1–4, Jared unpacks Jesus' 40 days in the wilderness and shows how fasting isn't about deprivation—it's about uncovering a deeper hunger that only Jesus can satisfy. From Old and New Testament examples of fasting to a personal story of how it led to a life-changing decision, this message lands on a simple but powerful truth: fasting moves us toward complete dependence on God and deeper intimacy with Jesus. Here's a couple key takeaways - Make space this week to practice fasting—even for a meal or part of a day—and pay attention to what it reveals about where you're really seeking satisfaction. - When you're tempted or struggling, fight back with Scripture, just like Jesus did in the wilderness. - Spend time asking God if there's something He's inviting you to repent of or surrender to Him. SUBSCRIBE for weekly sermons, stories, and other resources: https://www.youtube.com/@GracePointNWA?sub_confirmation=1 ============================= Connect with Grace Point Church: ============================= Instagram: https://instagram.com/gracepointnwa Facebook: https://facebook.com/gracepointnwa Website: https://gracepointchurch.net #Sermon #GracePointChurch #NorthwestArkansas
This Sunday at the 10am we are continuing our series in the book of Zechariah and, Senior Pastor, Sam Williamson, will be preaching on Zechariah 7-8 - From Fasting to Feasting
The Real Truth About Health Free 17 Day Live Online Conference Podcast
Fasting resets your taste buds, supports microbiome repair, and offers practical tips for dining out, travel, and long-term habit change. #MicrobiomeReset #PalateReboot #HealthyHabits #HealthTalks
Semaglutide Slows Biological Aging A randomized, placebo-controlled study published in Nature Communications found semaglutide slowed biological aging markers by nine percent on the DunedinPACE epigenetic clock in adults living with HIV-associated metabolic disease, with simultaneous improvements across inflammation, heart, kidney, liver, and brain markers. Host Dave Asprey breaks down why this isn't a weight loss story. It's a metabolic inflammation story. He explains why the GLP-1 mechanism hitting insulin signaling, oxidative stress, and inflammatory pathways simultaneously is the real finding, and makes the case that your metabolic markers and your aging markers are the same numbers. Sources: https://www.medicalnewstoday.com/articles/glp-1-drugs-ozempic-wegovy-may-slow-biological-aging https://www.nature.com/articles/s41467-026-72861-3 https://today.ucsd.edu/story/study-popular-glp-1-drug-may-slow-down-biological-aging FDA Approves First New Sunscreen Ingredient in 20 Years The FDA approved bemotrizinol as a permitted OTC sunscreen active ingredient, the first new approval in roughly two decades, clearing it for adults and children six months and older with broad UVA and UVB coverage and low skin absorption. Host Dave Asprey explains why twenty years of regulatory lag left American consumers with inferior chemistry while Europe moved on, why he's watching independent absorption data before updating his own stack, and why consistency of use matters more than perfect formulation when sun protection remains one of the most evidence-backed longevity interventions available. Sources: https://www.fda.gov/news-events/fda-newsroom/press-announcements/fda-expands-sunscreen-options-first-time-20-years https://www.accessdata.fda.gov/scripts/cder/omuf/index.cfm?event=OrderDetail&orderid=OTC000039 https://www.usatoday.com/story/news/health/2026/06/09/new-sunscreen-ingredient-bemotrizinol/90477659007/ Deoxyribose Gel Matches Minoxidil in Hair Regrowth Study Researchers testing a topical gel made from deoxyribose, the sugar backbone of DNA, saw roughly 80 to 90 percent hair regrowth in a mouse model of male-pattern baldness, matching minoxidil results and showing new follicle formation and increased blood vessel activity in treated areas. Host Dave Asprey breaks down why mouse hair regrowth studies have a long history of failing to translate to humans, what a plausible circulation-based mechanism would actually need to show in human trial data before it's worth acting on, and why the molecule itself is interesting enough to keep watching. Sources: https://www.reddit.com/r/Biohackers/comments/1tyt87w/researchers_found_that_a_gel_made_from/ https://www.sciencealert.com/surprise-hair-loss-breakthrough-a-dna-sugar-gel-sparks-robust-regrowth Caffeinated Chewing Gum and Exercise Performance A systematic review and meta-analysis of 21 studies found caffeinated chewing gum produces a small but real ergogenic effect for muscular strength and countermovement jump height, with buccal absorption delivering caffeine faster than capsules or drinks in a five to twenty-five minute pre-training window. Host Dave Asprey breaks down why delivery mechanism is an underrated variable in caffeine optimization, why timing matters as much as dose, and why a modest but measurable edge on a cheap and accessible tool is exactly the kind of practical biohack worth understanding. Sources: https://pubmed.ncbi.nlm.nih.gov/42228847/ https://doi.org/10.1519/JSC.0000000000005530 https://www.reddit.com/r/Biohackers/comments/1u0acgc/fastacting_caffeine_does_caffeinated_chewing_gum/ Vitamin A Overdoses Surge Nearly 40 Percent Medical News Today reported a 38.7 percent spike in vitamin A overdoses in early 2025, driven by online misinformation claiming high-dose vitamin A treats or prevents measles, a claim with no clinical support and real toxicity risk from fat-soluble accumulation in the liver. Host Dave Asprey explains the actual hepatotoxicity and bone demineralization risks of preformed retinol excess, draws the critical distinction between preformed retinol and beta-carotene that got lost in the misinformation cycle, and makes the case that mechanism is not a dosing protocol and confusing the two is how people get hurt. Sources: https://www.medicalnewstoday.com/amp/articles/vitamin-a-overdoses-rose-by-38-7-2025-how-to-get-right-amount World Cup 2026 and Mass Gathering Health Risk With the 2026 FIFA World Cup underway, public health researchers are flagging dense international crowds, high-volume travel, and shared indoor and outdoor spaces as an elevated transmission environment for respiratory illness. Host Dave Asprey reframes the conversation away from germ exposure and toward immune terrain, explains why your resilience going into a high-contact environment is a variable you actually control, and lays out the pre-exposure preparation window that matters most for anyone traveling or attending large events this summer. Sources: https://www.healthline.com/health-news/2026-fifa-world-cup-health-risks-protect-yourself This episode is designed for biohackers, longevity seekers, and high-performance listeners who want mechanism-level clarity on GLP-1 aging biology, sunscreen chemistry and regulatory science, emerging hair regrowth research, caffeine delivery optimization, supplement toxicity risk, and immune terrain preparation for mass gathering events. Host Dave Asprey connects randomized clinical data, epigenetic clock research, consumer health regulation, and real-world optimization protocols into actionable frameworks for extending healthspan, sharpening performance, and staying ahead of the science. New episodes every Tuesday, Thursday, Friday, and Sunday. Keywords: semaglutide biological aging, GLP-1 epigenetic clock, DunedinPACE aging marker, PCGrimAge mortality risk, bemotrizinol FDA approval, new sunscreen ingredient 2026, UVA UVB broad spectrum sunscreen, deoxyribose hair gel, minoxidil alternative hair regrowth, caffeinated chewing gum performance, buccal caffeine absorption, pre-workout caffeine timing, vitamin A overdose toxicity, preformed retinol hypervitaminosis, fat-soluble vitamin accumulation, World Cup 2026 health risk, immune terrain optimization, mass gathering respiratory illness, biohacking news 2026, longevity research, Dave Asprey, The Human Upgrade Thank you to our sponsors! - Viome | Check it out at viome.com and use code 10DAVE for 10% off. It's time to stop guessing and start knowing your body. - Beyond Wonderland Conference | Oct 13 - 14, 2026. Get your ticket now at wonderlandconference.com. - iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE Resources: • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Intro 00:41 – Story 1: Ozempic Slows Aging Clocks 01:53 – Story 2: New Sunscreen Approved 03:12 – Story 3: DNA Sugar & Hair Regrowth 04:38 – Story 4: Caffeine Gum & Performance 06:13 – Story 5: Vitamin A Overdose Spike 07:59 – Story 6: World Cup & Immune Prep 09:34 – Outro See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Welcome to the first episode of the Summer Protein Sparing Modified Fasting Series on the Optimal Protein Podcast. In this episode, Vanessa introduces the science, history, and practical application of protein sparing modified fasting, or PSMF, as a powerful tool for fat loss and body recomposition. Check out the Protein-Sparing Modified Fasting Library at ketogenicgirl.com and use code VANESSA for 20% off. Vanessa explains how PSMF was originally developed to help preserve lean body mass during severe energy restriction, why it differs from water fasting or traditional low-calorie dieting, and how prioritizing protein can help support satiety, fat loss, and muscle retention. This episode also explores the origins of PSMF with Dr. George Blackburn and Dr. Bruce Bistrian, its use in bariatric and physique-prep settings, and why strategic high-protein, lower-calorie days may be especially helpful for those who want to lose fat while protecting hard-earned muscle. You'll learn what a PSMF day can look like in practice, including protein targets, calorie ranges, lean protein choices, and how to combine PSMF days with maintenance days for a more sustainable approach. In this episode, Vanessa covers: What protein sparing modified fasting is Why preserving lean mass matters during fat loss How PSMF differs from water fasting The history of PSMF and its clinical origins Why protein supports satiety and metabolic rate How PSMF may support rapid fat loss without sacrificing muscle Practical meal structure, macros, and food examples Why resistance training is key for body recomposition Who PSMF may and may not be appropriate for Summer PSMF Series Re-Release Note: This episode was previously released on the Optimal Protein Podcast and is being re-released as part of the Summer Protein Sparing Modified Fasting Series. The PSMF Library is officially live
HEALTH NEWS Study links low vitamin C levels in the blood plasma to reduced brain connectivity Study: Tart Cherry Supplementation Alters Muscle Protein Profile After Exercise Socioeconomic factors may leave more lasting imprint on children's brains than IQ or parenting style Fasting-mimicking diet reduces gum disease inflammation Low blood pressure shows strongest link to Alzheimer's disease Study links low vitamin C levels in the blood plasma to reduced brain connectivity Hirosaki University (Japan), June 10 2026 (News-Medical) Previous research has uncovered associations between diets higher in vitamin C and lower risk of cognitive impairment in older adults. However, few studies have looked directly at vitamin C levels in blood plasma and potential associations with brain structure and connectivity within brain networks. To help fill that gap, Nagaya and colleagues analyzed magnetic resonance imaging (MRI) scans and plasma vitamin C levels of 2,044 adults over the age of 64. Specifically, they measured the volume of each participant's gray and white brain matter (accounting for individual differences in total brain volume between participants). They also evaluated connectivity within the default mode network, which is associated with several cognitive functions, such as attention and autobiographical memory. After statistically accounting for other factors the researchers found that participants with lower plasma vitamin C levels tended to have lower gray matter volume, as well as lower connectivity within the default mode network. These findings suggest the possibility that optimal levels of vitamin C in blood plasma could potentially support cognitive function and counteract cognitive decline. However, the findings do not confirm any such cause-effect relationship between vitamin C levels and brain health. Study: Tart Cherry Supplementation Alters Muscle Protein Profile After Exercise University of Exeter (UK), June 11 2026 (Natural News) Researchers recruited 34 healthy, recreationally active young men and assigned them to receive either a placebo, a low-dose tart cherry concentrate, or a high-dose tart cherry supplement, according to the study report. Participants consumed their assigned supplement for seven days before completing a muscle-damaging workout and continued supplementation for three days afterward, for a total intervention of 10 days. The study found that tart cherry supplementation significantly altered the muscle's protein profile following exercise-induced damage. Changes were observed in proteins involved in muscle structure, contraction, cellular repair processes, and immune-cell activity within muscle tissue. These findings suggest that tart cherry polyphenols may influence the way muscles respond to and recover from the stress of exercise. Researchers also detected significant increases in hippuric acid, a compound produced when gut microbes break down polyphenols from tart cherries and other plant foods. Participants with higher levels of hippuric acid tended to maintain better muscle function following exercise-induced damage. Socioeconomic factors may leave more lasting imprint on children's brains than IQ or parenting style Washington University in St. Louis, June 11 2026 (Medical Xpress) After analyzing hundreds of biological, psychological, social and environmental factors related to children's development, researchers at Washington University School of Medicine in St. Louis found that a family's financial situation and the resources and opportunities in a child's neighborhood had the strongest connection to brain development. Socioeconomic factors accounted for about 16% of the variability in measures of children's brain function—far more than IQ, parenting style and health history. As part of the study, the researchers analyzed brain scans from nearly 12,000 children ages 9 to 10 to see how a child's environment, health and regular activities are related to brain development. Of the hundreds of factors examined, the team found that the socioeconomic status of a child's family had the strongest relationship with that child's brain structure and function. Further, the parts of the brain that reflect socioeconomic factors were the same areas most sensitive to sleep and stress, suggesting that socioeconomic disadvantage affects the brain indirectly through disrupted sleep and chronic stress. Of the top 40 variables linked to brain function, 37 were socioeconomic, and of the top 40 tied to structure, 35 were socioeconomic. These included the social and economic resources in the child's neighborhood, akin to the overall wealth of an area. Strong influences included family income, homeownership, poverty rates and access to transportation. The remaining top variables were related to sleep, screen time and stress. Fasting-mimicking diet reduces gum disease inflammation Kings College London, June 11 2026 (Eurekalert) People who follow a short-term low-calorie diet may have reduced markers of inflammation associated with gum disease. A new study by King's College London highlights how lifestyle modifications could be important alongside plaque control in managing gum disease. The research included 28 patients from across hospitals in Spain, split into two groups – those who followed a five-day restrictive diet, versus a control group who continued their usual diet. Patients who fasted ate 1,100 calories for two days, then 750 calories for three days. The sixth day gently introduced more calories with soft foods – then their diets returned to normal by the seventh day. This was repeated three times in six months, with patients reporting the diet easy to stick to. After six months, samples were analysed from the patients' blood and gingival crevicular fluid – liquid that comes from the small space between your tooth and gum, which helps gums stay healthy and fight germs. Those who fasted had reduced markers of inflammation in samples from blood and gum tissue compared to those whose diets stayed the same, including lower levels of C-reactive protein, a general indicator of inflammation around the body. The fasting group also had reduced molecules linked to inflammation specifically in the gums, compared to controls. Low blood pressure shows strongest link to Alzheimer's disease Michigan Technological University, Jun 10 2026 (News-Medical) Numerous types of cardiovascular disease and CVD risk factors were linked to a higher risk of Alzheimer's disease, with low blood pressure showing the strongest connection, according to a new analysis published today in the Journal of the American Heart Association What are the key findings of the analysis? Adults with hypotension (low blood pressure) were about three times more likely to develop Alzheimer's and nearly twice as likely in the All of Us study when compared to individuals who did not have low blood pressure. Across both datasets, adults with high blood pressure (hypertension) were 1.6 times more likely to have Alzheimer's disease, compared to people without hypertension. Participants who had a previous stroke had a 1.5 times higher risk for Alzheimer's disease in the UK Biobank and 1.85 times in All of Us. Those with irregular heartbeat (or atrial fibrillation, also called AFib) were about 1.5 times more likely to have Alzheimer's disease compared to those without AFib.
How to Reverse Cognitive Decline, Grow Your Hippocampus, and Protect Your Brain from Alzheimer's Disease with Nutrition, Exercise, Sleep, and Stress Reduction Your brain is physically shrinking right now, and most people have no idea it's happening. In this episode, you will discover the exact mechanisms behind cognitive decline, why brain fog is always treatable, and the proven strategies to grow your brain back, protect your memory, and slash your Alzheimer's risk regardless of your genetics. -Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Dr. Majid Fotuhi, a neuroscientist and neurologist who earned his PhD from Johns Hopkins University and his medical degree from Harvard Medical School. He currently serves as an adjunct professor at the Mind/Brain Institute at Johns Hopkins while also teaching at George Washington University and Harvard Medical School. With 37 years of experience in clinical practice, teaching, and neuroscience research, Dr. Fotuhi pioneered the Brain Fitness Program, a multidisciplinary approach to cognitive performance and brain vitality at any age that has produced measurable results documented in peer-reviewed journals. He is the author of three books including the bestselling The Invincible Brain and one of the world's leading experts on neuroplasticity, hippocampus growth, and successful aging. If anyone has earned the right to tell you your brain can get better, it is him. Dr. Fotuhi and Dave break down why Alzheimer's is not a single disease but a soup of modifiable problems, why your lab results can show "normal" while your brain is starving, and how the five pillars of brain health connect directly to longevity, mitochondria function, and human performance. They also get into the brain effects of GLP-1s, the therapeutic promise of psychedelics like psilocybin and ketamine, the role of nootropics and supplements like B12, lithium orotate, and CoQ10, and why your VO2 max may be the single most important number for brain aging. . You'll Learn: Why 97% of Alzheimer's cases involve multiple modifiable causes and what to do about each one How to physically grow your hippocampus through exercise, meditation, and nutrition Why "normal" lab ranges are actively harming millions of people and what optimal actually looks like The 7 everyday things that are shrinking your brain right now How stress, loneliness, and isolation cause measurable brain atrophy Which supplements including B12, lithium orotate, CoQ10, and nootropics support long-term brain health Why VO2 max predicts brain aging better than almost any other marker What psychedelics like psilocybin and ketamine actually do to your brain according to a Johns Hopkins neurologist How the APOE4 gene affects Alzheimer's risk and why exercise can erase that risk entirely Why mitochondria health is the foundation of both brain function and longevity Thank you to our sponsors! - Viome | Check it out at viome.com and use code 10DAVE for 10% off. It's time to stop guessing and start knowing your body. - BrainTap | Go to http://braintap.com/dave to get $100 off the BrainTap Power Bundle. - Pique | Go to Piquelife.com/dave for 20% off. - BodyHealth | Visit BodyHeath.com and use code DAVE20 for 20% off your first purchase Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Majid Fotuhi, Dr. Majid Fotuhi, The Invincible Brain, brain health, cognitive decline, Alzheimer's prevention, hippocampus, neuroplasticity, brain fog, memory loss, APOE4, brain shrinkage, B12 deficiency, lithium orotate, CoQ10, nootropics, VO2 max, mitochondria, longevity, anti-aging, biohacking, brain optimization, sleep optimization, stress reduction, functional medicine, human performance, psilocybin, ketamine, GLP-1, semaglutide, telomeres, BDNF, brain training, cognitive performance Resources: • Learn More About Dr. Fotuhi's Work At: https://drfotuhi.com/ • Purchase Dr. Fotuhi's New Book The Invincible Brain: https://a.co/d/0iHCgPpL • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 00:59 – Intro 03:00 – Cannabis & Nicotine 04:15 – Understanding Alzheimer's 05:38 – Five Pillars Explained 07:55 – Best Cognitive Training 09:08 – Brain Size & Growth 12:36 – B12 & Lab Ranges 17:48 – Head-to-Toe Evaluation 24:17 – Sex & Brain Health 25:43 – Loneliness & Isolation 33:59 – ApoE4 Genetics 35:28 – Alzheimer's Declining 48:44 – Lithium & Brain 59:38 – VO2 Max & Fitness 1:06:42 – Psychedelics 1:09:38 – GLP-1s & Brain 1:12:38 – Closing & Action Steps See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In this episode, Dr. David Jockers reveals a powerful olive oil fasting trick that can help activate autophagy, the body's natural cellular cleanup system. You'll learn how high-polyphenol olive oil can support fat burning, reduce inflammation, and promote cellular repair. This simple protocol can be done alongside meals for maximum benefits. Discover the key compounds in extra virgin olive oil—oleuropein, oleocanthal, and hydroxytyrosol—and how they hijack your metabolism to flip the switch from storage to fat burning. Learn why the peppery bite matters and how it signals your cells to repair and regenerate efficiently. Find out how to choose the right olive oil and protect its potency. Dr. Jockers explains why fresh-pressed, high-polyphenol oils from unripe olives make the biggest impact on mitochondrial health. Apply these tips to improve energy, brain function, and overall metabolic performance. In This Episode: 00:00 Olive Oil Is Tainted 00:30 Secret Fasting Trick 01:14 Podcast Updates 04:38 Autophagy Fat Burning 06:27 How Autophagy Works 08:09 Five Autophagy Triggers 12:27 Avoid Fake Olive Oil 12:59 Choose High Polyphenol 14:39 Two Tablespoons Daily 15:13 Polyphenol Targets 16:51 Wrap Up And Resources 17:21 Final Podcast Outro Most olive oils sitting on grocery store shelves are stale and stripped of their beneficial antioxidants. Fresh-pressed olive oil is loaded with powerful polyphenols that support heart health, brain function, and healthy aging. Dr. Jockers recommends sourcing olive oil directly from small family farms for maximum freshness and flavor. Get a free full-size bottle for just $1 shipping through Fresh Pressed Olive Oil and experience the difference yourself. Visit http://drjockersoliveoil.com/ Switch to Manukora Honey, packed with bioactive compounds like MGO to support your gut and immune health. This antioxidant-rich honey is the perfect replacement for processed sweeteners. Save up to 31% and get $25 in free gifts with the starter kit. Visit manukora.com/drjockers to claim your offer today! "The stronger the peppery bite in olive oil, the stronger the signal for cellular healing." ~ Dr. Jockers Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio Resources: Get a free full-size bottle for just $1 shipping, visit http://drjockersoliveoil.com/ Visit manukora.com/drjockers to claim your offer today! Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https:/www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/
“I wanna hear THAT at my grocery store, when I'm going for the meat section…” Whether it's the song we all rise for at sports ball events, the first song on Rush's “Fly By Night” album (not to mention the first song on Anthrax's EP of classic rock covers), or the sing-along, encore at the end of a rock show, ANTHEMS represent a clarion call, a rallying cry that unites fans in unspeakable joy, unity, and celebration. It's almost always the song that EVERYONE knows (even your grandmother) and is very much NOT a deep cut. “AC/DC's kind of an anthem band…they have at least one on every album…” In fact, ANTHEMS are those kinds of songs where, if you hear one in a public place: at a bar, a restaurant, the grocery store, or a friend's party, you're not going to NOT like it. Sure, it's probably the most well-known, popular, played into the ground, mainstream “hit” that EVERYONE (again, probably even your grandmother) is familiar with, but no matter what song it is or where you might hear it, ANTHEMS are guaranteed to get you fired up, lift your spirit, and bring a smile to your face. “I wanna do a little birthday squig…” Find out what's happening “THIS FRIDAY”, realize that birthdays are the anniversaries of life, and JOIN US for a Bunkerpoon birthday celebration full of cake, refreshments, and good cheer as we cuss and discuss the unifying power behind rock and metal ANTHEMS. Visit www.metalnerdery.com/podcast for more on this episode Help Support Metal Nerdery https://www.patreon.com/metalnerderypodcast Leave us a Voicemail to be played on a future episode: 980-666-8182 Metal Nerdery Tees and Hoodies – metalnerdery.com/merch and kindly leave us a review and/or rating on your favorite Podcast app Follow us on the Socials: Facebook - Instagram - TikTok Email: metalnerdery@gmail.com Can't be LOUD Enough Playlist on Spotify Metal Nerdery Munchies on YouTube @metalnerderypodcast Show Notes: (00:01): “I think I just turned it up…”/ “I'm upright and taking nourishment…”/ “I'll give myself the bean…”/ “I'll put it wherever you want…you want it on the inside or the outside?” / ***WARNING: #listenerdiscretionisadvised *** / #keepitthrashy / “Maybe he just unlocked another dimension with his weed…”/ “Dr. Pepper, Captain Morgan, and PB&J's…”/ #yeah / #McDonalds #DirtyDrPepper #Rim / “Was the rim the best part?” / “If you have foam down there, you should really go see your doctor…to have him finish you to completion…”/ ***WELCOME BACK TO THE METAL NERDERY PODCAST AND THE BUNKERPOON CENTER FOR METAL EXCELLENCE!!!*** / #happybirthday / #birthdayepisode / “I eat once a day…I'm the lightest I've been in 3 years…”/ “A handful of food, 5 times a day…”/ #cavemandiet / “Fasting is the way…”/ “Now they're saying that sugar is WORSE than heroin…”/ “It's all mental…” (07:37): ***PATREON US at patreon.com/metalnerderypodcast *** / #SpiritInTheSky / “I was looking at the name: I thought it said ‘My Boss'…”/ ***SOCIAL MEDIA US at #MetalNerderyPodcast on #YouTube #Facebook #InstaGram and #TikTok *** / #drysockets and #wisdomteeth #viralaf / #Pyscroptic GATHERING A VENOMOUS HERD / (The Pulse of Annihilation – 2026) / #technicaldeathmetal / #Tasmania #Australia #AussieMetal / “They got a Wiki page, that's saying something…”/ Tasmania, Australia (“Yeah…”) / “How any albums do they have?” / “Let's go through the album titles…”/ “You wanna watch a video?”/ #youwatchamovie / ARCHITECTS OF EXTINCTION / “Those guys are re-tah-diculous!” / The reaction of laughter to unbelievable riffs and technical prowess (18:18): “So here's what we've got to contend with…I'm gonna ask you, right here in front of everybody…” / “You think God listens to this podcast, dude?”/ “I wanna do a little birthday squig in the beginning…”/ “This year marks the 25th anniversary of Pig Destroyer's Prowler In The Yard, which is like the Reign In Blood of grindcore…”/ “I've got a kink now, where I can't get off unless Stephen Hawking is watching…”/ “I hate this so bad…”/ “This is beautiful…this is art.” / #PigDestroyer JENNIFER/CHEERLEADER CORPSES (Prowler In The Yard – 2001) / #TwentyFifthAnniversary #ProwlerInTheYard / “Oh, I farted…”/ “A little bit of WHAT?” / PISS ANGEL / “Is that better or worse?”/ “Should we start calling birthdays anniversaries instead of birthdays?” (24:00): #TheDocket METAL NERDERY PODCAST PRESENTS: ANTHEMS / “It's gotta be bolth…” / #rockanthems #heavymetalanthems / “What is an anthem? What do you think of when you hear the word ‘anthem' (if it's metal or rock)?”/ “Everybody knows it…it gets people fired up…”/ “When the band plays the song where you all become a part of the show…that's the sing along…”/ “What is the first anthem you can think of?” / “Everybody knows it…it's the one that your grandmother has heard…it's the non-deep cut…”/ “What would Van Halen's anthem be?”/ #BetterOffDead / “What would AC/DC's anthem be?”/ “AC/DC's kind of an anthem band…they have at least one on every album…”/ “Did we just unlock a new dimension here?” (30:06): “What's a Zeppelin anthem?” / “We're all humans, who cares?”/ #markthetime / “Anthems are one of those things…if you hear it at a public place like in a bar, a restaurant, or even at the grocery store…”/ “Cart…buggy…”/ “You can't NOT like it…even if you're a #Rush super deep cut fan…”/ #BlackSabbath WAR PIGS (Paranoid – 1970) / “Now we're smiling, all of a sudden…”/ “I don't know if you've ever heard this before…about that song…those first few words…it almost has a country vibe to it…the vocal…”/ “They put the Eventide voice machines on him…”/ “All the guitar nerds will get that…”/ “What's an Eventide? Is that like a dildo or something? What do you do with that?”/ “What about Ozzy anthems?” (38:48): #Motorhead ACE OF SPADES (Ace Of Spades – 1980) / “This is one of the most metal parts, evah!”/ “If your doctor doesn't recommend metal to you as a lifestyle improvement and a medical treatment, find a different doctor.”/ “Was the Van Hagar more anthem-y than the Roth era?” / “Yeah…you've got to, with the hairdryer and the whole thing…you don't remember the video?” / #hairdryerASMR / “Soooo…for metal bands…”/ #IronMaiden THE NUMBER OF THE BEAST (The Number Of The Beast – 1982) / “Everybody in America is like: ‘You went to the pub and got pissed off? What's wrong with you?' / “I've got one…”/ #QuietRiot METAL HEALTH (Metal Health – 1983) / “Assgrinder?”/ “That's a sing-along…”/ “Which do you think was bigger?” / “I think that's what possibly killed Twisted Sister…”/ #TwistedSister I WANNA ROCK (Stay Hungry – 1984) / #No / “How much fun was that?” / “Every band probably has their own anthem…”/ “Testament, what would be theirs?” / “For the mainstream customer…but for their fans, it would be…”/ “It is a weird anthem…that's probably one of their encores…” (51:55): “Everybody knows the Pantera one…”/ “At a bar, at a party, at a friend's house…if I hear it in a public place…I'm not complaining…I'm cool with that.”/ “It still feels like it belongs to you…”/ “Do you feel like they (Metallica) are almost in the AC/DC bucket?” / “Does your grandmother know Dyer's Eve?” / “What's Creed's anthem?”/ #Pantera COWBOYS FROM HELL (Cowboys From Hell – 1990) / “I wanna hear THAT at my grocery store, when I'm going for the meat section…”/ #markthetime / “Fun and anthems kinda go together…”/ “I don't NOT like ‘Walk'…” (58:58): “I got another one for us metal heads…”/ #StormtroopersOfDeath MARCH OF THE S.O.D. (Speak English Or Die – 1985) / “Does #Anthrax have an anthem?” / “Okay, so how about Priest?” / #abigone / “Let me know if you think this is THEIR anthem…it's gotta be…”/ “THIS FRIDAY!” / #keepitin / “That was awesome…”/ #KoRn BLIND (KoRn – 1994) / “That's gotta be, right?” / “Are you ready!?” / “This Friday…are you ready?” (1:04:00): “What is the most recent rock or metal anthem you can think of?” / “Has everybody lost their ability to do anthems?”/ “The anthem is the call to arms…”/ “Here's my answer to that question…in my opinion…”/ “See, I thought that was Cake…” / #TheWhiteStripes SEVEN NATION ARMY (Elephant – 2003) / “I'll take the bottom off?” / “What's the band that everybody fucks with…everybody hates on them…?”/ “Nickelback has some anthems, for sure…now that you mention it, maybe not…”/ “That's how I clap, by the way…”/ THANK YOU FOR JOINING US!!! / #untilthenext #outroreel
After 30 years in health, Dr. Mindy is calling time on the rules.This solo episode is one of the most personal things she's shared on this podcast. It covers two big ideas: the science and story behind why she stopped fasting for most of the past year and the five health habits she's deliberately walking away from in 2026.First, flex fasting. When cortisol is high from grief, trauma, illness, perimenopause, or chronic stress rigidly pushing through long fasting windows doesn't support the body. It depletes it. Dr. Mindy shares what happened when she lost a close friend and found herself in an acute stress state, what the research says about prolonged fasting and the HPA axis, and how she developed a new approach she's calling flex fasting: a more intuitive, body-led way to use fasting as a tool without turning it into a rule.Then the five things she's giving up: counting (macros, biometrics, followers, all of it), the gym, other people's urgency, productivity over health, and information overconsumption. Each one is a direct response to what the wellness industry has quietly done to us — turned health into a full-time job with a performance review.RESOURCES MENTIONED:Fast Like a Girl: https://www.drmindypelz.com/booksAge Like a Girl: https://www.drmindypelz.com/booksSubstack Article "I Stopped Fasting for a Year": https://substack.com/@drmindypelz/Carb Manager App carbmanager.com, available on iOS, Android, and webThe Movement Diet: Redefining Fitness at Every Age with Katy BowmanStudy: Prolonged Fasting, HPA Axis & Cortisol - https://pmc.ncbi.nlm.nih.gov/articles/PMC12736288/Study: Estrogen & Cortisol Regulation - https://academic.oup.com/jcem/article/102/12/4457/4587523Midlife Women Fasting Trial - https://www.nature.com/articles/s41467-025-65678-zStudy: Self-Selected Fasting Windows - https://www.nature.com/articles/s41591-024-03375-yBEAM Minerals, use code MINDY for 20% off: https://www.beamminerals.com/?oid=4&affid=648LMNT, get a free sample pack with your order: https://bit.ly/drinklmntpelzTo view full show notes, resources mentioned, transcripts, and more, visit
Series Title: Old Paths New Power Scripture Passage: Matthew 6:16-18 & 9:14-15 Stream Date: June 7, 2026
Dr. William Li: Eat to Beat Disease, Extend Longevity, and Hack Your Vascular Health Your body already has a built-in cancer defense system, and the foods you eat can rival prescription drugs at activating it. In this episode, you'll discover what 720,000 living centenarians reveal about longevity, why microplastics are reaching your brain through your nose, and how your blood vessels hold the real key to biological aging. -Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Dr. William Li, an internationally renowned physician, scientist, and two-time New York Times bestselling author of "Eat to Beat Disease" and "Eat to Beat Your Diet." As President and Medical Director of the Angiogenesis Foundation, Dr. Li's groundbreaking research has led to the development of more than 40 new medical treatments impacting care for over 70 diseases including diabetes, heart disease, blindness, and obesity. His TED Talk, "Can We Eat to Starve Cancer?", has surpassed 11 million views, making him one of the most trusted voices at the intersection of functional medicine and food as medicine science. Together they dig into the biology of SuperAgers, the vascular markers that predict how long you'll live, and why flow-mediated dilation may be the most underrated biohacking measurement tool available today. Dave shares what happened after four separate gene therapies, including klotho and VEGF, and Dr. Li explains why your metabolism, mitochondria, and gut microbiome show up in the data on every centenarian ever studied. They also get into the microplastic crisis, the cribriform plate pathway that delivers airborne particles directly to your brain, and why your tongue is the first place your body quietly stores fat. You'll Learn: What centenarian research reveals about immune function, gut health, and vascular resilience Why 50% of food extracts matched or outperformed cancer drugs in head-to-head angiogenesis testing How microplastics travel through your nose directly to your central nervous system What flow-mediated dilation and pulse wave velocity tell you about your true biological age Why your hind-third tongue fat is an overlooked early warning sign for sleep apnea and metabolism problems What Dave's four gene therapies (klotho, VEGF, follistatin) actually did to his body How the vagus nerve connects gut health to brain optimization, stress resilience, and longevity Why genetics now accounts for roughly half of longevity outcomes, and what that means for the future of gene therapy How to use biohacking tools to compound your health the same way you compound financial returns Thank you to our sponsors! - Beyond Wonderland Conference | Oct 13 - 14, 2026. Get your ticket now at wonderlandconference.com. - Amp | If you're ready to make fitness fit into your life, go to amp.ai to check it out - Caldera + Lab | A small habit with big results. Go to CalderaLab.com/DAVE and use code DAVE for 20% off your first order. - Calroy | Go to Calroy.com/DAVE for exclusive discounts on Arterosil HP, Vascanox HP and all Calroy products. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: William Li, Dr. William Li, Eat to Beat Disease, angiogenesis, food as medicine, centenarians, SuperAgers, longevity, anti-aging, biohacking, vascular health, flow-mediated dilation, pulse wave velocity, microplastics, cribriform plate, gene therapy, klotho, VEGF, follistatin, mitochondria, metabolism, gut health, vagus nerve, sleep apnea, functional medicine, human performance, brain optimization, cancer prevention, inflammation, immune system Resources: • Learn More About Dr. Li's Work At: https://drwilliamli.com • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 02:33 – William's Background 06:21 – Food vs. Cancer Drugs 14:09 – Gene Therapy 23:50 – Centenarian Research 27:41 – Stress & the Vagus Nerve 37:31 – Vascular Health 42:34 – Microplastics 53:19 – Novel Biomarkers See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
***JOIN THE NEXT MASTER YOUR FASTING CHALLENGE THAT STARTS June 10th, 2026!*** We'll GUIDE you on how to FAST to LOSE FAT for good, and use ‘fast cycling' to achieve uncommon results! REGISTER HERE! Click the link for DATES, DETAILS, and FAQs! In this episode, Dr. Scott Watier and Tommy Welling dive deep into what they call the insulin matrix — the idea that chronic disease, weight loss resistance, and metabolic dysfunction are fundamentally insulin problems that develop quietly for years before showing up in labs or on the scale. Inspired by a conversation between Dr. Rhonda Patrick and Dr. Ben Bikman, the hosts explain why fasting is uniquely powerful not just for losing weight, but for changing how and where the body stores and releases energy at a cellular level — shrinking overfilled fat cells rather than simply creating a calorie deficit. They break down why a consistently high-insulin environment, even with good food choices, can keep the body locked in fat-storage mode and why stacking more daily "insulin-off hours" through foundational fasting is the most direct lever for restoring metabolic flexibility. The hosts also walk through the key lifestyle multipliers that either amplify or undermine the fasting effect — sleep, movement, food quality, and stress management — and why matching your fasting intensity to your current life load produces better long-term results than white-knuckling aggressive extended fasts. Listeners leave with a clear, trackable one-week action plan focused on morning energy, cravings, and fasting comfort as early signs that the insulin matrix is finally shifting in their favor. Take the NEW FASTING PERSONA QUIZ! - The Key to Unlocking Sustainable Weight Loss With Fasting! Resources and Downloads: SIGN UP FOR THE DROP OF THE ULTIMATE GUIDE TO BLOOD SUGAR CONTROL GRAB THE OPTIMAL RANGES FOR LAB WORK HERE! - NEW RESOURCE! FREE RESOURCE - DOWNLOAD THE NEW BLUEPRINT TO FASTING FOR FAT LOSS! SLEEP GUIDE DIRECT DOWNLOAD DOWNLOAD THE FASTING TRANSFORMATION JOURNAL HERE! Partner Links: Get your FREE BOX OF LMNT hydration support for the perfect electrolyte balance for your fasting lifestyle with your first purchase here! Get 25% off a Keto-Mojo blood glucose and ketone monitor (discount shown at checkout)! Click here! Our Community: Let's continue the conversation. Click the link below to JOIN the Fasting For Life Community, a group of like-minded, new, and experienced fasters! The first two rules of fasting need not apply! If you enjoy the podcast, please tap the stars below and consider leaving a short review on Apple Podcasts/iTunes. It takes less than 60 seconds, and it helps bring you the best original content each week. We also enjoy reading them!
What does it look like to go from 500 pounds to a CrossFit coach - not out of inspiration, but because fear was the only thing in the room?In this episode, Jamison sits down with Athena Perez: affiliate owner, coach, and author of a two-part memoir about identity, worth, and what fitness spaces get dangerously wrong.We explore how compounding habits shape who we become long before we notice, why a 40-day fast became Athena's clearest window into emotional eating and genuine purpose, and why placing people on pedestals - in the gym or anywhere else - always costs you something.
This week on the goodsugar podcast, Ralph Sutton and Marcus Antebi tackle some of the most popular food myths and nutrition debates circulating online today.They discuss whether reheated carbs are actually healthier, if cooked tomatoes provide more nutrition than raw ones, the truth about coffee and dehydration, juice cleanses, sugar fears, intermittent fasting, digestion, weight loss, and why so much nutrition advice can be misleading.Along the way, Ralph shares his experience losing over 100 pounds, while Marcus explains why meal timing, digestion, and lifestyle habits may matter more than most diet trends.00:00 Intro 01:00 Is Reheated Pasta Actually Healthier? 03:00 Cooked vs Raw Tomatoes 04:10 Does Coffee Really Dehydrate You? 06:20 Are We Too Overstimulated? 09:00 Oatmeal vs Oat Bran 13:15 Why People Drink Juice Cleanses 17:20 Can Fasting Reset Your Immune System? 19:20 The Truth About Sugar 23:20 Is Intermittent Fasting Worth It? 28:00 Ralph's 100+ Pound Weight Loss Journey 30:30 Final Thoughts & Wrap UpTEXT us your questions at 718-306-3906!The goodsugar store is the epitome of cool, nestled at 3rd avenue + 69th street!
Dr. Tom Curran asks Fr. Kurt Nagel: How did you celebrate the Feast of Corpus Christi? What's the science behind the eucharistic miracles? How long did saints fast, surviving only on the Eucharist alone? What does it mean to become a “living monstrance?"
Why does Jesus teach His followers to fast? Drawing from Matthew 6:16-18, Pastor Joe explores the purpose of fasting and how it helps us dedicate ourselves more fully to God and His Kingdom.
I used to weigh 300 pounds. I tried every restrictive diet, became a vegan, and trained 90 minutes a day for 18 months with absolute zero results. Everything changed when I drank a cup of yak butter tea at 18,300 feet in Tibet. Within 30 seconds, my severe brain fog lifted, and my metabolism completely shifted.In this video, I break down exactly why adding sugar to your morning coffee is destroying your metabolism, spiking your insulin, and keeping you fat. I explain the hard science behind the alternative: blending "fat cubes" (grass-fed butter) and MCT oil into your coffee. I reveal how this specific combination of butyrate, CLA, and medium-chain triglycerides bypasses traditional digestion to go straight to your liver, instantly converting into ketones for pure brain fuel. You'll learn how eating more fat actually trains your body to burn its own stored fat, allowing me to hit 4.8% body fat at 50 years old with a biological age in my 30s—without hunger, without a 3 PM crash, and without living in the gym.Thank you to our sponsors!Suppgrade Labs | Grab your DAKE and Minerals 101 duo at shopsuppgradelabs.com and use code DAVEPOD for 15% off todayViome | Check it out at viome.com and use code 10DAVE for 10% off. It's time to stop guessing and start knowing your body.iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVETimestamps:0:00 – Intro 00:42 – Pancreatic Cancer Halted by Virus Injection 01:44 – Teens & AI Therapy Chatbots 03:13 – GLP-1 Drugs Cut Breast Cancer Risk 04:30 – Russia's $26B Longevity Program 06:18 – Sauna vs. Cold Plunge 09:10 – ClosingConnect with Dave Asprey!Website: https://daveasprey.comTikTok: https://www.tiktok.com/@daveaspreyofficialInstagram: https://www.instagram.com/dave.asprey/Facebook: https://www.facebook.com/Daveaspreyofficial/X: https://x.com/daveaspreyYouTube: https://www.youtube.com/c/daveaspreybprThe Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/Danger Coffee: https://dangercoffee.com/DAVE15Dave Asprey's BEYOND Conference: https://beyondconference.com/Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15Upgrade Labs: https://upgradelabs.com40 Years of Zen: https://40yearsofzen.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Psalm 31:7 offers a powerful reminder that God sees our struggles, understands our pain, and cares deeply for our souls. In this devotional, Lauren Fletcher explores the comforting truth that God is not distant from our suffering. Through the stories of Leah and Hagar, Scripture reveals a compassionate God who notices those who feel overlooked, unloved, forgotten, or alone. Even when we cannot find the words to pray, God remains attentive to our circumstances and actively works on our behalf. Highlights God sees our struggles, even when no one else notices. Leah's story demonstrates God's compassion toward the overlooked and unloved. Hagar's encounter with God reveals Him as El Roi, "the God who sees me." God's care is not dependent on us having the perfect words to pray. Scripture consistently shows God moving on behalf of those who are hurting. The Lord meets people in seasons of loneliness, rejection, and distress. God's awareness of our pain is evidence of His deep love for us. Believers can trust that they are never forgotten or abandoned by God. Join the Conversation Have you experienced a time when God reminded you that He saw your pain, needs, or circumstances? How does knowing that God is El Roi—the God who sees you—change the way you approach difficult seasons? Continue the conversation with the Crosswalk community here: https://forums.crosswalk.com/ Do you want to listen ad-free? When you join Crosswalk Plus, you gain access to exclusive, in-depth Bible study guides, devotionals, sound biblical advice, and daily encouragement from trusted pastors and authors—resources designed to strengthen your faith and equip you to live it out boldly. PLUS ad free podcasts! Sign Up Today! Full Transcript Below: He Sees Us By Lauren Fletcher Bible Reading: “I will be glad and rejoice in your unfailing love, for you have seen my troubles, and you care about the anguish of my soul.” - Psalm 31:7 This month, my church has been participating in 21 Days of Prayer and Fasting. As I was praying one morning, I came across a sweet passage of scripture. In the story of Jacob, Leah, and Rachel, God meets Leah in a very personal way. Though she was the first wife of Jacob, Rachel was the one he wanted and worked for. Genesis 29 says, “When the LORD saw that Leah was unloved, he enabled her to have children, but Rachel could not conceive. So Leah became pregnant and gave birth to a son. She named him Reuben, for she said, ‘The LORD has noticed my misery, and now my husband will love me’” (Genesis 29:31-32). It touched my heart that the LORD saw Leah’s circumstances and moved. She did not pray and ask, she did not cry out for God’s help. He just saw what she was going through and acted. How amazing that God sees what’s going on with us and will act on our behalf, even when we do not ask. Have you ever had a circumstance like this in your life, where God has moved, even before you were able to ask? The story continues, “She soon became pregnant again and gave birth to another son. She named him Simeon, for she said, ‘The LORD heard that I was unloved and has given me another son’” (Genesis 29:33). I love how Leah recognizes God has seen and heard her situation. She acknowledges Him in this. Intersecting Faith & Life: There’s another important passage in the scriptures where we learn that God sees us. A beloved name of God is El Roi. This name is given to Him by Sarai's (Sarah’s) servant, Hagar, in Genesis 16, in the wilderness (Genesis 16:7). The LORD had told Abram that he would have descendants, that he would have a son. Abram trusted the LORD in this (Genesis 15:4-6). “Now Sarai, Abram’s wife, had not been able to bear children for him. But she had an Egyptian servant named Hagar. So Sarai said to Abram, ‘The LORD has prevented me from having children. Go and sleep with my servant. Perhaps I can have children through her.’ And Abram agreed with Sarai’s proposal” (Genesis 16:1-2). After Hagar became pregnant, she did not treat Sarai well (Genesis 16:4). The scripture says, “Then Sarai treated Hagar so harshly that she finally ran away. The angel of the LORD found Hagar beside a spring of water in the wilderness, along the road to Shur” (Genesis 16:6b-7). Hagar was met in her distress, in her place of difficulty. She was seen. “Thereafter, Hagar used another name to refer to the LORD, who had spoken to her. She said, ‘You are the God who sees me.’ She also said, ‘Have I truly seen the One who sees me?’” (Genesis 16:13). Hagar was not forgotten. She was sought out by the Lord. Something we can take away from these scriptures, these stories of how God worked in these women’s lives, is that if He sees them, He sees us. He will work on our behalf when we ask, but also when we don’t. He sees, and He works on our behalf because He loves us. It is this same love that caused the LORD, who saw the troubles of the Israelites in Egypt, to be moved to deliver them (Exodus 3-4). Exodus 4:31 says, “Then the people of Israel were convinced that the LORD had sent Moses and Aaron. When they heard that the LORD was concerned about them and had seen their misery, they bowed down and worshiped.” Doesn’t this just touch your heart? How wonderful and loving the Lord is. He knows what’s going on with you. He sees, and He cares. He will help you, because He loves you. Even if you haven’t been able to ask, don’t worry. He sees us. Further Reading: Psalm 56:8 Genesis 29 Exodus 3-4 Genesis 16 Discover more Christian podcasts at lifeaudio.com and inquire about advertising opportunities at lifeaudio.com/contact-us.
Making Space, Digital Fasting: Michael Knapstad | June 7, 2026
Christian Dating Service Reviews | Dating Advice | Christian Singles Podcasts
For many believers longing for a godly marriage, the waiting season feels endless—filled with dating apps, well-meaning advice, and quiet prayers that seem unanswered. If you’re a Christian single asking, “Lord, is this the one? What is Your will for my love life?” fasting combined with prayer offers a powerful, biblical pathway to clarity, surrender, and breakthrough. Fasting isn’t about earning God’s favor or manipulating outcomes. It’s about humbling yourself, denying the flesh, and creating space to hear the Father’s […] The post The Role of Fasting in Seeking God’s Will for Your Love Life appeared first on Christian Singles Advice | Christian Dating Advice Tips. Related posts: A Life Long Love: 7 Traits That Hurt Your Chances Fasting for Breakthrough in Relationships How to Surrender Your Love Life to God Life Advice for Mature Christian Singles The Meaning of “The Love of My Life”
Pancreatic Cancer Halted by Virus Injection Researchers injected an engineered virus directly into pancreatic tumors in three patients — the virus replicated inside malignant cells, triggered an immune response, and stopped tumor growth and spread at an intentionally low early dose. Host Dave Asprey breaks down why oncolytic viruses can do what chemotherapy can't, how the tumor's dense biological wall becomes less of an advantage when a virus can replicate inside it directly, and why a measurable response at a safety dose is the kind of early signal that changes how he's watching this field. Sources: https://www.newscientist.com AI Chatbots and Teen Mental Health A new survey shows roughly one in five adolescents and young adults are now going to AI chatbots when they feel sad, anxious, nervous, or stressed, with usage heaviest in the 18–21 range. Host Dave Asprey explains why general-purpose language models designed to be engaging are dangerous as a substitute for real mental health support, why false reassurance from a chatbot may make the pipeline to real care harder to reach, and why this is a health systems story masquerading as a tech adoption story — and what parents need to do about it. Sources: https://www.nbcnews.com GLP-1 Drugs Cut Breast Cancer Risk Penn Medicine published a retrospective analysis of over 111,000 women finding GLP-1 exposure associated with about 35% lower odds of breast cancer in the full cohort and around 30% lower in a matched comparison group. Host Dave Asprey breaks down why this isn't just a weight loss story — it's a metabolic dysfunction story — explains the insulin resistance, inflammation, and hormonal environment mechanisms that may be driving the signal, and makes the case that this finding should be reshaping how oncologists and OBGYNs think about high-risk patients right now. Sources: https://www.pennmedicine.org Putin's $26 Billion Longevity Program The Wall Street Journal reports that Russia has made anti-aging research a Kremlin-level national priority through a $26 billion program including gene therapy, organ bioprinting, and xenotransplantation, led by Putin's daughter Maria Vorontsova and physicist Mikhail Kovalchuk. Host Dave Asprey breaks down what's geopolitical theater, what's legitimately frontier science, and why the real question is whether any findings will make it out to the broader research community or get locked inside a state program. Sources: https://www.wsj.com https://www.france24.com Sauna vs. Cold Plunge A landmark Finnish study tracked over 2,300 men for nearly 21 years and found increasing sauna frequency associated with dramatically lower cardiovascular and all-cause mortality — strongest at four or more sessions per week. Host Dave Asprey settles the debate with the actual data, explains what heat shock proteins and cold shock proteins actually are and why the evidence base behind them is nowhere near equivalent, and calls out the wellness marketing presenting early-stage mouse model research as the cold water equivalent of two decades of human mortality outcomes. Sources: https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2521522 This episode is designed for biohackers, longevity seekers, and high-performance listeners who want mechanism-level clarity on cancer treatment breakthroughs, adolescent mental health and AI, metabolic drivers of disease, geopolitical longevity science, and the real evidence behind popular recovery modalities. Host Dave Asprey connects emerging clinical research, objective epidemiological data, and real-world optimization protocols into actionable frameworks for extending healthspan, sharpening performance, and staying ahead of the science. New episodes every Tuesday, Thursday, Friday, and Sunday. Keywords: oncolytic virus pancreatic cancer, engineered virus tumor treatment, AI chatbot teen mental health, adolescent AI emotional support, GLP-1 breast cancer risk, semaglutide cancer prevention, metabolic dysfunction root cause disease, Putin longevity program Russia, New Health Preservation Technologies, anti-aging biotech geopolitics, sauna longevity mortality data, cold plunge cold shock proteins, RBM3 heat shock proteins, sauna vs cold plunge evidence, biohacking news 2026, longevity research, Dave Asprey, The Human Upgrade Thank you to our sponsors! - Suppgrade Labs | Grab your DAKE and Minerals 101 duo at shopsuppgradelabs.com and use code DAVEPOD for 15% off today - Essentia | Go to https://myessentia.com/dave and use code DAVE for $100 off The Dave Asprey Upgrade. - iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE Resources: • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Intro 00:42 – Pancreatic Cancer Halted by Virus Injection 01:44 – Teens & AI Therapy Chatbots 03:13 – GLP-1 Drugs Cut Breast Cancer Risk 04:30 – Russia's $26B Longevity Program 06:18 – Sauna vs. Cold Plunge 09:10 – Closing See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
The Nurses Report on America Out Loud with Ashley Caputo, RN, FMP – Fasting, faith, and biblical nutrition come together as Ashley Caputo and Amy Whitlock explore how ancient rhythms support modern healing. They discuss intermittent fasting, whole foods, cellular repair, gut health, and spiritual discipline, inviting listeners to return to simple, intentional habits that nourish the body, mind, and spirit each day...
Dom Alcuin Reid, who was "illicitly" ordained a priest (against the wishes of his own bishop) by an unnamed Cardinal in good standing has a serious call to action for Catholics concerned with the growing tensions between the SSPX and the Vatican.Sponsored by Pray Latinhttps://praylatin.comSources:https://www.returntotradition.orgorhttps://substack.com/@returntotradition1Contact Me:Email: return2catholictradition@gmail.comSupport My Work:Patreonhttps://www.patreon.com/AnthonyStineSubscribeStarhttps://www.subscribestar.net/return-to-traditionBuy Me A Coffeehttps://www.buymeacoffee.com/AnthonyStinePhysical Mail:Anthony StinePO Box 3048Shawnee, OK74802Follow me on the following social media:https://www.facebook.com/ReturnToCatholicTradition/https://twitter.com/pontificatormax+JMJ+#popeleoXIV #catholicism #catholicchurch #catholicprophecy#infiltration
The Nurses Report on America Out Loud with Ashley Caputo, RN, FMP – Fasting, faith, and biblical nutrition come together as Ashley Caputo and Amy Whitlock explore how ancient rhythms support modern healing. They discuss intermittent fasting, whole foods, cellular repair, gut health, and spiritual discipline, inviting listeners to return to simple, intentional habits that nourish the body, mind, and spirit each day...
POWER FOR TODAY is intended to equip the believers with the supernatural dimension of God through the teaching of the unadulterated word of God.
Verse by verse study through the book of Acts Chapter Ten and Verse Thirty
Sulforaphane, Detox Pathways, and the Science of Microplastic Removal Microplastics are building up inside your brain, blood, and reproductive tissue, and most detox protocols do nothing to remove them. This episode gives you the cellular science behind why toxins accumulate, which three detox pathways control your ability to excrete them, and what the latest research shows actually moves microplastics, heavy metals, BPA, and benzene out of your body.. -Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR -For next week, 25% off all Mara Labs products when you go to www.mara-labs.com/DAVE and use code DAVE at checkout. After June 11th, the code will return to the standard 15% off. Host Dave Asprey sits down with Dr. John Gildea, a Johns Hopkins-trained PhD with 60 scientific publications and over 20 NIH-funded studies, and David Roberts, co-founder of Mara Labs and co-creator of BrocElite, the only naturally derived stable form of sulforaphane available in a capsule. Together they bring decades of research-backed biohacking and functional medicine insight into one of the most pressing longevity conversations of our time. They break down the lysosome, your cell's built-in incinerator, and explain exactly why it gets clogged with microplastics, advanced glycation end products, and other toxins that won't break down. New research shows that sulforaphane triggers a process called lysosomal surface translocation, which releases those trapped particles so your body can finally excrete them. An in-house Mara Labs study confirmed the excretion pathway: microplastics come out in feces. In the original study, the individual measured the highest microplastic levels ever recorded, and a repeat study a year later showed dramatically lower baseline microplastic levels, suggesting consistent use compounds the benefit over time. You'll Learn: Why microplastics accumulate inside lysosomes and what sulforaphane does to release them How the three detox pathways, glutathione, glucuronidation, and sulfation, work together to remove every major class of toxin What an in-house study revealed about how and where microplastics actually leave the body How toxic estrogen metabolites form and why sulforaphane is the most effective natural tool to reroute them Why berberine supports sleep optimization, ketosis, and blocks a cancer growth pathway most drugs cannot touch How sulforaphane boosts BDNF and neuroplasticity at the cellular level What microplastic sources in your home, including your dryer, rugs, and receipts, are doing to your toxin load daily Why losing weight releases stored toxins and what to take to protect your brain and metabolism during fat loss How sulforaphane activates the same AMPK longevity pathways triggered by fasting without restricting food Thank you to our sponsors! - iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE - HeartMath | Go to https://www.heartmath.com/dave to save 15% off. - Timeline | Go to timeline.com/dave and you'll get an additional 20% off your first month - Our Place | Stop cooking with toxic cookware and upgrade to Our Place today. With a 100-day risk-free trial, plus free shipping and returns, you can experience this game-changing cookware with zero risk. Visit: fromourplace.com/DAVE Use code: DAVE for 10% off sitewide Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Dr. John Gildea, David Roberts, Mara Labs, BrocElite, sulforaphane, microplastics, microplastic removal, lysosome, lysosomal surface translocation, detox pathways, glutathione, glucuronidation, sulfation, Nrf2 pathway, AMPK, TFEB1, BDNF, neuroplasticity, heavy metals, BPA, benzene, estrogen metabolism, toxic estrogen, xenoestrogens, berberine, BerbaLite, ResveraLite, c-Myc, cancer and estrogen, sleep optimization, ketosis, broccoli sprouts, isothiocyanates, PEITC, watercress, phase two detox, microplastic excretion, indoor air quality, HEPA filter, dryer lint microplastics, BPA receipts, endocrine disruptors, fat loss and toxins, autism and sulforaphane, ADHD and focus, vivid dreams and BDNF, fasting mimicry, anti-aging, biohacking, longevity, functional medicine, supplements, human performance, brain optimization, metabolism, cellular detox Resources: • For next week, 25% off all Mara Labs products when you go to www.mara-labs.com/DAVE and use code DAVE at checkout. After June 11th, the code will return to the standard 15% off. • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 0:00 – Trailer 1:55 – Intro & Context 4:48 – Microplastics & Sulforaphane 12:39 – Broccoli Sprouts Formulation 15:20 – Lab Origin Story 26:01 – Reducing Toxin Exposure 37:06 – Estrogen, Hormones & Berberine 52:46 – Autism, ADHD & Brain Health 59:01 – Wrap-Up See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
POWER FOR TODAY is intended to equip the believers with the supernatural dimension of God through the teaching of the unadulterated word of God.
Fasting trends have officially gone off the rails - and some of them are actually worth knowing about, while others come with side effects nobody seems to be talking about.So today, we're breaking it all down and cutting through the noise.We're covering:Sardine fasting - the reset trend with a side of gout nobody warned you about Water fasting - the most "true" fast, and why it's not for everyone The Fasting Mimicking Diet - the science-backed method where you actually get to eat Dopamine fasting - the trend that has nothing to do with food Why when you fast matters just as much as how long you fastPlus, the electrolyte reminder you probably needed heading into summer. And of course . . . today's feelgood thing.Dr Erin Boynton's Program I'm doing for back pain - click here Big thanks to our sponsor, ITL Health.More information on their magnesium formulations, designed with bioavailability in mind, can be found here:https://itlhealth.ca/
See omnystudio.com/listener for privacy information.
You're not imagining your fibromyalgia pain or symptoms. Discover common fibromyalgia causes and triggers, and learn how to find fibromyalgia relief by addressing the underlying issue.0:00 Introduction: Fibromyalgia explained 0:42 Fibromyalgia causes and triggers 1:45 Low vitamin D and fibromyalgia3:19 Mitochondrial damage and fibromyalgia symptoms5:00 What to do for fibromyalgia relief5:31 Fibromyalgia research and recovery7:58 Fixing low vitamin D 8:39 Magnesium deficiency and fibromyalgia symptoms 10:34 More fibromyalgia relief tips
Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/ Theresa's Instagram: https://www.instagram.com/livingrootswellness/ Timestamps: 0:00 – intro 1:36 – good vs. bad cravings: how to tell the difference 4:28 – how to use cravings to understand what your body actually needs 10:15 – healthy hunger vs compulsive eating 15:27 – should we limit calories, carbs, fat, or salt? are carbs addictive? 17:51 – one common reason people feel better on low-carb, keto, and carnivore diets 20:07 – how chronic stress and trauma shape cravings and compulsive behaviors 22:26 – is sugar really addictive like a drug? 26:08 – does a bad response mean it's a bad craving? 31:12 – how to understand your cravings 35:53 – your response to foods is only part of the picture 39:38 – where sauna, exercise, cold exposure, and fasting fall on the stress spectrum 45:14 – cold plunging vs saunas: why Jay says sauna is better 48:57 – pros and cons of fasting 51:35 – is exercise beneficial because it causes stress? 57:00 – the benefits of sauna use and whether heat shock proteins are really beneficial 59:39 – where walking, HIIT, saunas, and cold plunges fall on the “stress spectrum” 1:02:04 – why metabolic markers can improve from stressors 1:04:35 – can HIIT and endurance training ever be beneficial from a bioenergetic perspective? 1:06:55 – how much exercise is too much? 1:09:27 – how carbs restored energy and recovery for a former carnivore athlete
Needle-Free Peptides, US Manufacturing, BPC-157, Thymosin Alpha-1, GLP-1s, Microneedle Patches, and How to Avoid Contaminated Peptides Peptides are one of the most powerful tools in biohacking and anti-aging medicine, and until now, most people couldn't access them safely, legally, or without a needle. This episode changes that. -Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR -Go to Aminoinnovations.com and use “asprey20” for a discount through the next 7 days Host Dave Asprey sits down with Justin Kirkland, a longevity medicine expert with over 30 years in drug development and pharmaceutical innovation. Kirkland holds multiple drug synthesis and formulation patents, has founded multiple pharmaceutical companies, and is one of the few people in the world manufacturing peptides entirely on US soil, controlling every step of the synthesis process from raw amino acids to finished product. If you want to understand what is really inside your peptides and why it matters for your longevity and human performance, he is the person to listen to. Dave and Justin go deep on why most peptides on the gray market contain dangerous residual compounds that can spike liver enzymes and cause real harm, why Chinese-sourced APIs are not always what they claim to be, and how a new generation of needle-free delivery systems including microneedle patches and auto-injectors is making peptide therapy accessible to anyone serious about longevity and human performance. They also cover how AI and functional medicine are converging to make peptide protocols personalized based on genetics and microbiome status, why the thymus gland is one of the most overlooked anti-aging targets in the body, and what the suppression of peptide research reveals about who really controls your access to health tools. You Will Learn: Why many gray market peptides contain toxic residual acids that damage the liver and how to identify clean products How microneedle patches and auto-injectors are replacing traditional injections for peptide delivery Which peptides are most effective for longevity, immune system repair, and human performance including BPC-157, Thymosin Alpha-1, and growth hormone secretagogues Why your genetics and gut microbiome determine whether a peptide will work for you at all How the thymus gland controls your immune system and why it disappears by your mid-20s What the suppression of peptide research tells you about Big Pharma's control over your supplement and nootropics access Why US-manufactured peptides represent a new standard for safety and quality in biohacking How AI is transforming personalized peptide protocols in functional medicine Which peptides are overhyped and which ones actually move the needle on anti-aging and recovery How to store, mix, and dose peptides correctly to avoid the mistakes most people using them are making right now Thank you to our sponsors! - Danger Coffee | Grab yours at DangerCoffee.comand use code DAVEPOD at checkout for 15% off. - The One Device | Use code DAVE for $10 off at theonedevice.com/dave - Fatty15 is on a mission to support Healthy Aging for All, including all ages and stages of life. You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com DAVE and using code DAVE at checkout. - ENERGYbits | If you want a simpler, smarter way to support your body… this is it. Head to ENERGYbits.com and use code ASPREY for 20% off your order. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Justin Kirkland, peptides, needle-free peptides, microneedle patch, BPC-157, Thymosin Alpha-1, ipamorelin, CJC-1295, PT-141, KPV peptide, Dihexa, growth hormone secretagogue, peptide purity, TFA contamination, gray market peptides, US manufactured peptides, oral peptides, transdermal delivery, thymus gland, anti-aging, biohacking, longevity, functional medicine, peptide auto-injector, compounding pharmacy Resources: • Go to Aminoinnovations.com and use “asprey20” for a discount through the next 7 days • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Intro & Guest Welcome 01:55 – Censorship & Platform Bans 06:20 – Peptide Science & Bioavailability 07:20 – Delivery Methods 14:30 – Supply Chain & US Manufacturing 17:01 – Manufacturing Risks & Contamination 24:43 – Peptide Stacks 28:41 – Immune Peptides & Thymus 30:57 – Overhyped Peptides 41:00 – Alternative Delivery (Patches, Nasal, Rectal) 47:25 – Side Effects & Risk 50:30 – Mixing & Storage Tips 54:05 – Wrap-Up & Where to Buy See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
To Find Deplorable Janet--> https://open.spotify.com/show/3K5Xi9LugxNdI06GXSIjAp?si=m5hPD7OsS6eim1jACk84ewTo sign up for our Patreon go to-> Patreon.com/cultofconspiracypodcast To find the Meta Mysteries Podcast---> https://open.spotify.com/show/6IshwF6qc2iuqz3WTPz9Wv?si=3a32c8f730b34e79 To Join the Cajun Knight Patreon---> Patreon.com/cajunknight To Find The Cajun Knight Youtube Channel---> click herehttps://flavorsforest.com/cult/Become a supporter of this podcast: https://www.spreaker.com/podcast/cult-of-conspiracy--5700337/support.
I lived with severe brain fog for 15 years. I couldn't focus, my words didn't come easily, and I spent a fortune trying to fix it from the top down...little worked until I realized the problem wasn't in my head—it was in my feet.In this video, I break down the scientifically proven connection between your feet, your circulation, and your cognitive decline. We cover how your brain requires a massive 20% of your body's oxygen to function, and why sitting at a desk all day weakens the calf muscles that act as a "second heart" to pump that oxygenated blood back up to your skull. I also explain how modern cushioned shoes act as sensory deprivation chambers, muffling the critical signals your feet send to your brain. This sensory lack forces your nervous system into a constant, low-level survival state that completely kills your executive function. You don't need another brain supplement to get your mental edge back. You need to fix your foundation. I share the exact barefoot walking and foot-strengthening protocols I used to lift the fog and restore my cognitive sharpness.Thank you to our sponsors!Suppgrade Labs | Grab your DAKE and Minerals 101 duo at shopsuppgradelabs.com and use code DAVEPOD for 15% off todayEssentia | Go to https://myessentia.com/daveand use code DAVE for $100 off The Dave Asprey Upgrade.iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVETimestamps:00:00 – Personal Experience00:47 – Root Cause: Not in Your Head01:05 – Blood Flow and Brain Function02:10 – The Calf Pump03:52 – Foot Sensory Signals04:26 – Nervous System Impact06:22 – How to Fix It07:51 – Personal ResultsConnect with Dave Asprey!Website: https://daveasprey.comTikTok: https://www.tiktok.com/@daveaspreyofficialInstagram: https://www.instagram.com/dave.asprey/Facebook: https://www.facebook.com/Daveaspreyofficial/X: https://x.com/daveaspreyYouTube: https://www.youtube.com/c/daveaspreybprThe Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/Danger Coffee: https://dangercoffee.com/DAVE15Dave Asprey's BEYOND Conference: https://beyondconference.com/Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15Upgrade Labs: https://upgradelabs.com40 Years of Zen: https://40yearsofzen.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Enhanced Games Debut in Las Vegas as the First Openly Drug-Enabled "Biohacker Olympics" The inaugural Enhanced Games took place in Las Vegas with more than 40 elite athletes competing openly while using performance-enhancing drugs, a $25 million prize pool, and a $1 million world record bonus on the table. Host Dave Asprey, who serves on the advisory board of the Enhanced Games, breaks down why this event is less a sports story than a cultural signal: enhancement has moved from underground to prime time, and the institutions that spent decades controlling that conversation through drug testing and bans watched it happen on a stage in Las Vegas. Dave explains why WADA has always existed to protect institutions rather than athletes, why bodily sovereignty is the real issue at the center of this debate, and what it means that even with full transparency about what every athlete was taking, the records didn't fall quite the way you'd expect. The Enhanced Games are the closest thing yet to a public beta test for extreme human enhancement, and the data it generates will matter far beyond sport. Sources: https://www.nytimes.com/athletic/7302319/2026/05/23/enhanced-games-athletes-world-records-doping-steroids/ https://www.npr.org/2026/05/24/nx-s1-5831252/enhanced-games-steroids-olympics-trump https://www.bbc.com/news/articles/cedpz1zqp8po https://www.wusf.org/2026-05-24/the-enhanced-games-are-sunday-heres-what-to-know-about-the-controversial-event Kyle Busch's Death Showed How Severe Pneumonia Can Rapidly Escalate Into Fatal Sepsis NASCAR driver Kyle Busch died after severe pneumonia progressed into sepsis, a condition most people hear about but few truly understand until it is too late. Host Dave Asprey breaks down the biology of what happens when the immune system stops containing an infection and starts attacking the body systemwide, why sepsis can escalate from manageable symptoms to a life-threatening emergency faster than most people expect, and why even someone with great biomarkers and a dialed-in health stack can be blindsided by an acute inflammatory crisis. The warning signs matter: worsening breathing, confusion, rapid decline, and a sense that something is badly wrong are emergency symptoms, not signals to wait and see. Longevity is not only about optimization rituals. It includes knowing when your biology is in crisis and acting before the window closes. Sources: https://www.cnn.com/2026/05/24/health/what-is-sepsis-kyle-busch-wellness https://www.cnn.com/2026/05/26/health/video/sepsis-kyle-busch-medical-care-lead-jake-tapper https://www.michiganmedicine.org/health-lab/nascar-stars-death-shows-how-sepsis-can-kill-anyone-if-not-caught https://www.huffpost.com/entry/what-is-sepsis-kyle-busch_l_6a15a9c1e4b0ddcc84641f34 Menin Loss in the Hypothalamus May Be a Central Switch That Accelerates Aging New research in mice found that a protein called Menin in the hypothalamus may function as a central coordinator of biological aging across the whole body. When Menin declined, aging accelerated. When researchers restored it in older mice, memory improved and lifespan increased. Host Dave Asprey explains why this finding challenges the dominant wear-and-tear model of aging, what it means that the hypothalamus may be running a coordinated aging program rather than simply accumulating damage over time, and why a control-room model of aging points toward fundamentally different intervention strategies than chasing downstream symptoms like fatigue and memory loss. The research connects aging to neuroinflammation, which has direct implications for how biohackers think about hypothalamic health right now. It is still animal research, but the mechanistic case is strong and the implications for longevity science are significant. Sources: https://www.sciencedaily.com/releases/2026/05/260524012959.htm https://www.news-medical.net/news/20230323/Menin-protein-protects-against-aging-and-cognitive-decline.aspx https://www.eurekalert.org/news-releases/982100 https://www.eurekalert.org/news-releases/1116021 IL-6 Blockade With Tocilizumab Showed Early Promise for Treatment-Resistant Depression A small pilot randomized trial tested tocilizumab, an anti-inflammatory drug that blocks IL-6 signaling, in people with difficult-to-treat depression and found remission rates of 54% versus 31% with placebo. Host Dave Asprey breaks down why this result reframes depression as an immune biology problem for a meaningful subset of patients rather than a purely neurochemical one, and why the same inflammatory pathway that drives joint destruction in rheumatoid arthritis is showing up in the brains of people who don't respond to antidepressants. The practical implication is not to seek out a biologic drug off-label. It is to recognize that persistent low mood, fatigue, and low resilience may warrant a deeper biological workup than standard screening provides, starting with IL-6, CRP, and a full inflammatory panel. The brain is downstream of the immune system more than most psychiatry has been willing to admit, and this trial is the clearest evidence yet of why that matters. Sources: https://www.bristol.ac.uk/news/2026/may/pilot-trial-suggests-anti.html https://www.eurekalert.org/news-releases/1128678 https://www.medicalxpress.com/news/2026-05-trial-anti-inflammatory-drug-difficult.html https://clinicaltrials.gov/ New Science Paper Says Intrinsic Human Lifespan May Be About 50% Heritable A paper published in Science argues that the genetic contribution to human lifespan is roughly 50% heritable, far higher than previous estimates, once researchers correct for deaths caused by accidents, infections, and external causes unrelated to aging biology. Host Dave Asprey explains why this finding is liberating rather than deterministic, what it means that genetics loads the dice on lifespan more than the mainstream has been willing to admit, and why personalized longevity strategy matters far more than generic population-level advice. Your genes load the dice but you still roll them. The study pushes the field toward genetic stratification and biomarker-based personalization, and it validates the core premise that the same intervention will not produce the same outcome in every person. Get your genetics tested and build your strategy from your own baseline, not from what worked for the average person in a study. Sources: https://www.science.org/doi/10.1126/science.adz1187 https://pubmed.ncbi.nlm.nih.gov/41610249/ https://www.nature.com/articles/d41586-026-00300-w https://www.eurekalert.org/news-releases/1113892 This episode is designed for biohackers, longevity seekers, and high-performance listeners who want mechanism-level clarity on human enhancement, acute inflammatory risk, neuroendocrine aging, immune-driven depression, and the genetics of lifespan. Host Dave Asprey connects emerging clinical research, real-world performance culture, and actionable optimization frameworks into a clear picture of where biology actually drives outcomes and where most people are still managing symptoms instead of finding the mechanism. New episodes every Tuesday, Thursday, Friday, and Sunday. Keywords: Enhanced Games biohacking, performance enhancement bodily autonomy, WADA elite sport doping, Kyle Busch sepsis death, pneumonia sepsis escalation, sepsis warning signs, Menin hypothalamus aging, brain aging master switch, neuroendocrine aging longevity, tocilizumab depression IL-6, inflammation treatment-resistant depression, immune biology mental health, lifespan heritability genetics, longevity genetics personalization, genetic stratification healthspan, biohacking news 2026, longevity research 2026, healthspan optimization, inflammation testing CRP IL-6 Thank you to our sponsors! - HeartMath | Go to https://www.heartmath.com/dave to save 15% off. - The One Device | Use code DAVE for $10 off at theonedevice.com/dave - iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE Resources: • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Intro 00:38 – Story 1: Enhanced Games 01:49 – Story 2: Kyle Busch Death (Sepsis) 03:09 – Story 3: Menin Protein and Brain Aging 04:37 – Story 4: Inflammation and Depression 06:20 – Story 5: Lifespan Heritability 07:47 – Takeaway See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
How CD38, PARP, and Leaky Gut Are Destroying Your NAD Levels | Dr. Andrew Salzman Your NAD is being drained by two hidden enzymes, your gut may be the starting point of every aging process in your body, and creatine does something to your mitochondria that has nothing to do with muscle. This episode rewrites what you thought you knew about longevity, anti-aging biology, and how your body actually produces and delivers energy at the cellular level. -Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR -Explore all of Wonderfeel's products at: getwonderfeel.com/dave They are gifting a complimentary 7-day Youngr™ supply (mini pouch) with every order across any of their products. The code will be DAVE, and the campaign will be active through June 6th. Host Dave Asprey sits down with Dr. Andrew Salzman, a physician, inventor, and biomedical entrepreneur with more than 30 years of experience in drug discovery and development. An alumnus of Harvard Medical School, Yale University, and Columbia University, Dr. Salzman has authored more than 170 scientific publications and holds 50 patents. He invented the original clinical-stage PARP-1 inhibitor, leading to the world's first clinical treatment for raising NAD levels and fighting cancers caused by the BRCA1 and BRCA2 genes. Genentech licensed his breakthrough technology for $600 million. His research into gastrointestinal microbiota, autoimmune disease, oxidative stress, and mitochondrial ATP production now forms the foundation of how millions of patients get treated worldwide. Dr. Salzman names the two biggest NAD drains in your body, CD38 and PARP, and explains why taking NMN or NR alone is like filling a bathtub with the drain wide open. He breaks down the formulation science behind pairing NAD precursors with CD38 blockers like hydroxytyrosol alongside PARP-reducing antioxidants like ergothioneine, and delivers a paradigm-shifting explanation of creatine as an energy distribution network inside your cells. Rather than a simple muscle supplement, creatine acts as a high-speed ATP shuttle that carries energy from your mitochondria to the precise location and moment your brain, gut, and heart need it most. You'll Learn: Why NAD declines with age and which two enzymes are primarily responsible for draining it How CD38 rises with inflammation rather than NAD levels, and what that means for your supplement strategy Why creatine is one of the most underrated anti-aging and brain optimization supplements available How creatine functions as a spatial and temporal energy delivery network for your brain, gut, and heart Why the gut may be the origin point of the entire aging process and how that cascade unfolds decade by decade How leaky gut drives systemic inflammation, crashes NAD, and accelerates biological aging throughout the body What controls tight junction integrity and how ATP, butyrate, creatine, and fasting all play a role Why most creatine supplements fail to absorb properly and what to look for in a high-quality source How to rebuild your microbiome in three to four weeks through diet alone, without antibiotics Why walking immediately after a meal may be doing more harm than good to your gut lining Thank you to our sponsors! - Screenfit | Get your at-home eye training program for 40% off using code DAVE at https://www.screenfit.com/dave. - KILLSwitch | If you're ready for the best sleep of your life, order now at https://www.switchsupplements.com/and use code DAVE for 20% off - Pique | Go to Piquelife.com/dave for 20% off. - iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Dr. Andrew Salzman, NAD depletion, CD38 inhibition, PARP inhibition, NMN supplements, creatine ATP shuttle, leaky gut aging, tight junction integrity, inflammaging, lipopolysaccharide gut, flagellin toxin, butyrate gut healing, ergothioneine, hydroxytyrosol, peroxynitrite, superoxide mitochondria, creatine energy distribution, gut origin of aging, NAD bathtub analogy, BRCA PARP inhibitor, Wonderfeel, creatine monohydrate, intestinal permeability, microbiome butyrate, selective digestive decontamination, TMAO nitric oxide Resources: • Explore all of Wonderfeel's products at: getwonderfeel.com/dave • Order Youngr™: getwonderfeel.com/dave• Order ChocoCreatin™: getwonderfeel.com/dave• Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 01:12 – Introduction & BRCA Background 02:19 – DNA Damage & PARP 04:38 – Free Radicals & Oxidative Stress 11:37 – NAD & Antioxidant Defense 12:34 – CD38 & NAD Depletion 23:31 – The Gut-Aging Hypothesis 30:05 – ATP, Creatine & Energy Distribution 36:41 – Creatine as Energy Shuttle 51:09 – Microbiome & Gut Repair 59:21 – TMAO & Nitric Oxide Interference 1:03:52 – Flagellin & Gut Inflammation Research 1:09:45 – FDA & Pharmaceutical Incentives 1:16:05 – Closing See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
“Why did the Church end weekly fasting?” This question opens a discussion on the evolution of Church practices, alongside inquiries about the Church’s stance on jousting, the concept of limbo for infants, and the pastoral duties of priests. These topics reflect the diverse concerns and curiosities within the Catholic faith today. Join the Catholic Answers Live Club Newsletter Invite our apologists to speak at your parish! Visit Catholicanswersspeakers.com Questions Covered: 02:50 – Why Did the church kill off weekly fasting? 08:00 – I have heard the Church banned jousting. Does that mean we can't do that at Medieval Times? 13:27 – Is it acceptable for Catholics to believe in the limbo of the infants? 19:13 – How do I articulate the Catholic position that it is not faith alone that saves, without sounding like our works save us? 28:00 – Modeling Jesus in Dating Before Marriage 34:36 – I've been going through some ongoing stalking, hacking, and financial fraud. I thought I could go to the Church for help but they don't seem to be able to offer me support. What are the pastoral duties of a priest? I've been thinking of leaving the Catholic Church because of this. 43:54 – Why is it the norm in the US to receive communion in the hand and standing? Why did it change from what seems to be a more reverent posture? 48:09 – How can the Church hold up Mary and Joseph as an ideal marriage, when they did not consummate and therefore it would not have had a sacramental marriage? 51:23 – When should you leave your parish for another parish based on your priest teaching false things? My priest is very loving and kind, but is not on board with some doctrines and some sexual teaching of the Church?
The Hidden Causes of Brain Fog, Anxiety, and Chronic Illness: Mold, Parasites, Histamine, and Low Cortisol If you're exhausted, inflamed, and can't figure out why, the answer might be hiding in your histamine, your hormones, your home, or something living inside you that your doctor will never test for. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Dr. Jessica Peatross, a former hospitalist turned functional medicine powerhouse who walked away from a conventional medical career after discovering that 90% of disease traces back to lifestyle, environment, and the toxins most doctors ignore. After graduating magna cum laude and earning her medical degree from the University of Louisville, Dr. Jess pursued training in functional medicine, nutrigenomics, and alternative therapies, and now helps thousands of patients reverse chronic illness through her KillBindSweat method and WellnessPlus app. She is also the formulator and CMO of Aegis Formulas and a leading voice at international health conferences. If chronic illness, mold toxicity, or hormonal chaos is on your radar, she is the person you want in your corner. Together, Dave and Dr. Jess go deep into the hidden drivers of mystery symptoms that functional medicine is finally starting to crack open. They cover why low cortisol is more dangerous than high cortisol, how histamine and mast cell activation syndrome explain everything from anxiety and brain fog to endometriosis and POTS, and why most "Lyme disease" is actually undiagnosed mold toxicity. They also break down the parasite epidemic hiding in plain sight across the United States, the B vitamin mistake making millions of people sicker, and why your metabolism, mitochondria, and mental health are all downstream of things your standard lab panel will never catch. This episode also gets into the real story behind Dr. Jess surrendering her California medical license rather than comply with a system she believed was working against patient health. Her firsthand account of the medical board process is something every person who cares about medical freedom needs to hear. You'll Learn: Why everyone who is chronically sick has a low cortisol awakening response and what to do about it How histamine drives anxiety, racing thoughts, palpitations, bloating, skin issues, and hormonal chaos Why 90% of people diagnosed with Lyme disease actually have toxic mold and how to test for both The parasite epidemic in the U.S. and why standard testing misses most of it How the spike protein reactivates dormant viruses and feeds the histamine loop behind long COVID Why synthetic B6 causes the very neuropathy it is supposed to fix, and what to take instead The cortisol, adrenaline, and blood pressure connection that explains "wired but tired" How progesterone stabilizes mast cells and why estrogen dominance fuels inflammation and reactivity Why Dave Asprey uses low-dose cortisol, dexamethasone, and modafinil as part of his daily performance stack The mold binders that actually work, and which popular ones can harm hypermobile people How nicotine at low doses blocks spike protein from ACE2 receptors and protects the brain What the MTHFR gene, methylation, and folic acid have to do with breast cancer, depression, and estrogen detox Thank you to our sponsors! - iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE - KILLSwitch | If you're ready for the best sleep of your life, order now at https://www.switchsupplements.com/and use code DAVE for 20% off - Calroy | Go to Calroy.com/DAVE for exclusive discounts on Arterosil HP, Vascanox HP and all Calroy products. - Cowboy Colostrum | Get your gut right by going to cowboycolostrum.com/asprey for 25% off of your entire order. -Amp | If you're ready to make fitness fit into your life, go to amp.ai to check it outDave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Dr. Jessica Peatross, functional medicine, mast cell activation syndrome, histamine intolerance, long COVID brain fog, mold toxicity, chronic Lyme disease, parasite testing, low cortisol, cortisol awakening response, MTHFR methylation, B6 toxicity, P5P, folinic acid, estrogen dominance, progesterone therapy, spike protein reactivation, Epstein-Barr reactivation, POTS, wired but tired, Kill Bind Sweat, WellnessPlus, vaccine exemptions, mold binders, nicotine ACE2, adrenal insufficiency, RCCX gene Resources: • Go to https://drjessmd.com/ and use code ‘DRJESS' at checkout • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 00:33 – Releasing Medical License 03:21 – Chronic Illness Root Causes 05:00 – Hospital Nutrition 08:11 – Dave's Health History 10:22 – Parasites 20:02 – Nicotine 23:19 – Low Blood Pressure & Minerals 28:09 – B Vitamins & Methylation 33:45 – Autism & Genetics 40:13 – Toxic Mold 43:11 – ADHD Misdiagnosis 48:27 – Histamine & Mast Cells 50:56 – Long COVID & Spike Protein 58:56 – Cortisol 1:03:56 – Lyme Disease 1:09:58 – Mold Testing & Binders 1:16:37 – Closing See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.