Podcasts about ns2

The Nintendo Switch 2 finally arrives after years of rumors and rumblings. With such an anticipated system, it's no surprise that people are trying to get a sneak peek. Some early console arrivals have led to startup and menu sneak peeks, but not much more beyond that due to a necessary firmware patch on launch day. Summer Game Fest is also on the horizon this week, with gaming news sure to intensify throughout the week. All this and much more news make up another episode of the longest running video game podcast, Orange Lounge Radio! (Recorded June 1st. Date stamped 6/2 due to incorrectly posted audio previously)   Also in the News: * Pokémon Legends Z-A Release Date * Dragon Quest 1-2 HD Confirmed for Switch 2 * Layoffs at Playtonic * Warning about Magnets and Game Key Cards   All this and more on the show where EVERY gamer has a voice-- Orange Lounge Radio!   LIVE on the VOG Network, Sunday nights at 6 Pacific, 9 Eastern www.vognetwork.com   Mailbag: participate (at) orangeloungeradio dot com

Featuring: Michael "Boston" Hannon, Paul “Moonpir” Smith, and Alexander “TheNimp” Jolly Running Time: 1:10:59 Music by MusiM: Homepage | Bandcamp Livestream Archive: YouTube This week on That Video Game Podcast (TVGP) we chat about Assassin's Creed Shadows, Luck Be a Landlord, Blue Prince. NS2 preorders open soon, but with a caveat Become a patron of TVGP for just a few dollars a month at E1M1's Patreon Page! Get two month early access to Critical Misses, uncensored outtakes, and much more for just $5/month!

Depois de um dia voltado para detalhes do Nintendo Switch 2, a empresa japonesa reservou a quinta e a sexta-feira para apresentar alguns dos jogos de lançamento do novo console. Foi uma ótima oportunidade para que pudéssemos ver do que o sucessor do Nintendo Switch é capaz, além de ficar um pouco por dentro das tecnologias que acompanham a plataforma. O que será que achamos do Nintendo Treehouse?Edição por Alecsander Oliveira.Capítulos: (0:00) Introdução(2:49) Treehouse e Mario Kart World(23:19) Donkey Kong Bananza(33:28) Metroid Prime 4: Beyond(39:30) Nintendo Switch 2 Welcome Tour (A.K.A. Manual Pago do NS2)(48:05) Drag x Drive(53:22) BotW e TotK no Switch 2(1:02:32) GameChat e GameCube(1:07:06) Super Mario Party Jamboree(1:13:39) Kirby and the Forgotten Land(1:20:51) Street Fighter 6(1:28:26) Encerramento

这期是NS2节目插播导致延期的怪物猎人荒野节目 这期找来了本台的老猎人zero，但是往年这时候都在狩猎的人怎么突然有空来录节目了？ 那就说明这次游戏多少有些要被吐槽的点了

北京时间4月2日晚9点，任天堂举办NS2直面会，备受期待的Nintendo Switch2正式亮相。Switch2将于6月5日正式发售，日语版售价49980日元，折合人民币约2400元，多语言版售价69880日元，折合人民币约3400元。NS2双版本销售策略和偏高的价格遭到了玩家群体吐槽，同时首发游戏的名单也让许多人对新主机兴致寥寥。本期主播：老瘫、恶霸波、野人、小朱

千呼万唤始出来的NS2直面会，场内场外的内容非常繁杂多样，尽量给大家收集梳理一下。

相信围观了NS2直播的朋友们都知道发生了什么事情了 58分钟左右的好心情被最后2分钟的NS2报价迎头痛击 于是主播们终于还是没忍住，光速录制（骂）了出了这期老任迷惑行为大赏

This week on NintenDomain, we give our final (hopefully) predictions for the Nintendo Switch 2 or NS2. Plus we talk Hitman 3, Metaphor: Refantazio, Ys Oath in Felghana, Super Mario Party Jamoree, Sonic 3, and so much more! Support the show at: www.patreon.com/nintendomainpodcast Music: Intro: Ys Seven: Uncertainty in the Future Break 1: Super Mario Party Jamboree: Bowser's Keep 1 Break 2: Sonic Adventure 2: I am the Eggman Outro: The Legend of Zelda: The Wind Waker: Farewell King Hyrule Topic Times: 00:02:00 Switch 2 talk 00:35:49 Got Item: Hitman 3 Ranma 1/2 Super Mario Party Jamboree Romancing Saga 2: Revenge of the Seven Ys Memoire: Oath in Felghana 01:12:25 Sonic The Hedgehog 3 Movie Metaphor: Refantazio 01:34:19 Weekly Nintendo news        

Jak jsme předesílali, poslední virtuální studio před koncem základní části vypukne dnes, tedy v pátek 3. 1., od 17:45. Budeme se pochopitelně věnovat těm nejzajímavějším zápasům z 18. hracího týdne. A že nám jich NFL nabídne pořádnou řádku, o tom není pochyb! Stále nám ve vzduchu visí spousta otazníků. Kdo proklouzne na poslední postupovou pozici v AFC? Kdo uzme vítězství v NFC South, a hlavně kdo ovládne trůn celé konference NFC? Na to vše se podrobně podíváme. Přijďte nás pozdravit do živého vysílání na náš YouTube kanál! ------------------------- OBSAH: 0:00:08 Úvod0:02:49 Vyhlášení soutěže z živého vysílání0:04:36 Vyhlášení decemberové NFL.cz tipovačky0:06:27 Noriho informačné okénko0:10:21 Ondrovo navázání0:14:05 Ravens vs. Browns (NS6)0:22:43 Steelers vs. Bengals0:30:36 Falcons vs. Panthers0:36:03 Cowboys vs. Commanders0:41:26 Packers vs. Bears0:48:06 Titans vs. Texans0:50:50 Colts vs. Jaguars0:55:01 Patriots vs. Bills1:01:41 Komerční vložka aneb díků vzdání partnerům projektu NFL.cz1:06:34 Buccaneers vs. Saints (NFL.cz derby kola, NS6)1:15:13 Eagles vs. Giants1:19:41 Broncos vs. Chiefs (Telly TV zápas kola, NS6)1:26:20 Raiders vs. Chargers1:30:29 Rams vs. Seahawks1:38:01 Jets vs. Dolphins1:44:51 Vyhlášení soutěže Bold Picky s Matty Glamping1:46:01 Cardinals vs. 49ers1:50:57 Tigers vs. Vikings (SNF, NS2)2:14:34 Sázkařské okénko s Fortunou

I v čase vánočním přínašíme naše pravidelné virtuální studio. Budeme se pochopitelně povídat o bramborovém salátu, kaprovi, řízcích a dárcích. A možná taky trocho o fotbalu, protože NFL samozřejmě nikdy nespí a v těchto dnech nás čeká velká nálož napínavých soubojů. Zdaleka vše není rozhodnuto a tak si týmy musí dávat velký pozor, aby někde nezaškobrtly a nepřišly tak o vydobyté pozice. Začneme tentokrát ve středu v 16:00 abychom skončili před startem utkání KC@PIT. Přijďte nás pozdravit živě a třeba, přijde i Ježíšek! --------------------------- OBSAH: 0:00:11 Úvod0:04:26 Vyhlášení soutěže z živého vysílání0:08:17 Noriho informační okénko0:10:00 Ondry "superbowlové" navázání0:11:45 Draft párty trip do Green Bay0:19:18 Steelers vs Chiefs0:27:59 Texans vs Ravens0:38:12 Bears vs Seahawks (TNF, NS1)0:47:07 Patriots vs Chargers (NS6)0:55:42 Bengals vs Broncos (NS6)1:02:26 Rams vs Cardinals (NS2)1:07:25 Bills vs Jets1:11:49 Saints vs Raiders1:19:51 Komerční vložka aneb díků vzdání partnerům projektu NFL.cz1:23:07 Eagles vs Cowboys (NFL.cz derby kola, NS6)1:33:23 Giants vs Colts1:38:09 Buccaneers vs Panthers1:43:12 Jaguars vs Titans1:46:38 Browns vs Dolphins1:50:02 Vikings vs Packers (Telly TV zápas kola, NS6)2:02:06 49ers vs Lions (MNF, NS6)2:07:36 Vyhlášení soutěže Bold Picky s Matty Glamping2:08:58 Commanders vs Falcons (NFL.cz zápas kola, SNF, NS2)2:16:30 Sázkařské okénko s Fortunou

Za pár dní téměř po celém světě zvládne klid a pohoda Vánočních svátků. V NFL je to ale přesně naopak. Teď začíná ta největší bojová vřava o pár míst v play-off. Kdo tenhle závěrečný sprint zvládne nejlépe? Kdo načasuje ideální formu na vyřazovací boje? A kdo naopak už vyhlíží nadcházející draft? To jsou všechno palčivé otázky, které se pokusíme odpovědět v našem tradičním vysílání ve středu od 17:45 na našem Youtube. Jako vždy budeme rádi za každého diváka, který se stihne připojit živě. ---------------------------------------- OBSAH: 0:00:09 Úvod0:00:57 Vyhlášení soutěže z živého vysílání0:02:30 Norbertovo informačné okénko0:05:11 Nový NFL.cz Overtime0:09:58 Chargers vs. Broncos (NFL.cz Derby kola, TNF, NS6)0:25:22 Chiefs vs. Texans (NS6)0:36:08 Falcons vs. Giants0:48:59 Bills vs. Patriots0:57:37 Bears vs. Lions1:03:53 Colts vs. Titans1:11:52 Jets vs. Rams1:16:53 Komerční intermezzo aneb díků vzdání partnerům projektu NFL.cz1:21:03 Commanders vs. Eagles (Telly TV zápas kola, NS6)1:29:55 Panthers vs. Cardinals1:37:10 Bengals vs. Browns1:42:04 Seahawks vs. Vikings1:51:23 Raiders vs. Jaguars1:55:47 Dolphins vs. 49ers (NS6)2:05:22 Cowboys vs. Buccaneers (SNF, NS1)2:13:28 Packers vs. Saints (MNF, NS2)2:22:31 Ravens vs. Steelers (NFL.cz zápas kola, NS6)2:28:21 Sázkařské okénko s Fortunou2:32:32 Kupte si nové NFL.cz tričko na Superbowl párty

Den díkuvzdání je za námi a přinesl nám spoustu fotbalové zábavy. Neuvěřitelných osm televizních přenosů, studio až do noci a samozřejmě parádní bitvy! Nicméně fotbalový život kráčí mílovými kroky dál a před námi je další hrací týden. Týmy ze severních divizí zatím vypadají neohroženě a hned ve čtvrtek nás čeká doslova souboj titánů. Chiefs po utrápeném a šťastném vítězství nad Raiders čeká další divizní soupeř. Povede se Chargers konečně vyzrát na favorita? Spoustu dalších otázek se pokusíme naťuknout a zodpovědět tradičně ve středu v 17:45 na našem youtube kanálu a jako vždy vás čekají soutěže o zajímavé ceny! -------------------------------------------- OBSAH: 0:00:09 Úvod 0:01:00 Vyhlášení soutěže z živého vysílání 0:02:36 Vyhodnocení NFL.cz tipovačky za november 0:04:17 NFL.cz draft párty 2025 v Green Bay 0:05:38 Vyřizování objednávek na e-shopu NFL.cz do Vánoc 0:07:30 NFL.cz Thanksgiving studio review 0:19:40 Detroit vs. Packers (Zápas kola, TNF, NS6) 0:33:50 Titans vs. Jaguars 0:42:45 Dolphins vs. Jets 0:49:10 Vyhlášení soutěže s Telly TV 0:51:15 Vikings vs. Falcons (Telly TV zápas kola, NS6) 0:58:56 Giants vs. Saints 1:04:12 Eagles vs. Panthers 1:13:09 Steelers vs. Browns 1:22:59 Komerční intermezzo aneb poděkování partnerům projektu NFL.cz 1:25:36 Chiefs vs. Chargers (Derby kola, SNF, NS6) 1:34:50 Buccaneers vs. Raiders 1:45:27 Cardinals vs. Seahawks 1:51:51 Rams vs. Bills (NS6) 1:58:09 49ers vs. Bears 2:06:16 Cowboys vs. Bengals (MNF, NS2) 2:10:32 Sázkařské okénko s Fortunou

Je tady jeden z vrcholů základní části NFL. Už zítra oslaví celé Spojené státy Den díkůvzdání, který slovy jednoho z nejznámějších komentátorů a trenérů spojuje v sobě ty nejkrásnější věci na světě. Přátele, rodinu, jídlo a fotbal. V NFL se říká, že od tohoto data už jde opravdu do tuhého. Nejlepší týmy nastavují formu tak, aby ideálně neprohráli už po celý zbytek roku. Komu se to povede a kdo naopak zůstane před branami vytoužených úspěchů? To vše proberem klasicky ve středu v 17:45 na našem Youtube kanále. Těšíme se na vás a jako vždy připomínáme, že vyhodnocení soutěží proběhne live! ----------------------------------- OBSAH: 0:00:10 Úvod 0:02:17 Vyhlášení soutěže z živého vysílání 0:03:49 Noriho informačné okienko 0:10:53 Lions vs Bears (Telly TV zápas kola, NS1) 0:18:14 Vyhlášení soutěže s Telly TV 0:19:55 Cowboys vs Giants (NS1) 0:29:17 Packers vs Dolphins (NS1) 0:43:23 Chiefs vs Raiders (NS5) 0:49:56 Falcons vs Chargers 0:59:38 Vikings vs Cardinals 1:10:16 Patriots vs Colts 1:15:27 Jets vs Seahawks 1:21:07 Komerční intermezzo aneb poděkování partnerům projektu NFL.cz 1:27:11 Bengals vs Steelers (Derby kola) 1:36:44 Commanders vs Titans 1:44:51 Jaguars vs Texans 1:51:01 Saints vs Rams 2:01:02 Panthers vs Buccaneers 2:07:53 Soutěž Bold Picky s Matty Glamping 2:09:53 Bills vs 49ers (SNF, NS2) 2:19:24 Broncos vs Browns (MNF, NS6) 2:25:44 Ravens vs Eagles (Zápas kola, NS2) 2:34:03 Sázkařské okénko s Fortunou

V druhé polovině základní části už se definitivně začíná oddělovat zrno od plev. Někteří favorité drží svoje pozice, ale někteří naopak selhali. V letošním ročníku to vypadá na spanilé jízdy týmů ze severních divizí. Dokáže je někdo zastavit? Byla to pro Kansas tak trochu „povinná“ prohra? Musíme počítat s Chargers? A spousta dalších otázek určitě padne v našem tradičním vysílání ve středu 20. 11. od 17:45. Zkuste přijít včas, protože zároveň budeme losovat výherce 90denního balíčku od Telly! ------------------------------ OBSAH: 0:00:10 Úvod0:00:57 Vyhlášení soutěže z živého vysílání0:02:57 Browns vs Steelers (TNF, NS6)0:18:05 Bears vs Vikings0:26:07 Colts vs Lions (Telly TV zápas kola, NS6)0:36:28 Dolphins vs Patriots0:43:47 Giants vs Buccaneers0:49:54 Commanders vs Cowboys0:56:51 Panthers vs Chiefs1:00:33 Komerční intermezzo aneb poděkování partnerům projektu NFL.cz1:03:52 Seahawks vs Cardinals (Derby kola, NS6)1:14:53 Texans vs Titans1:19:26 Raiders vs Broncos1:28:51 Packers vs 49ers1:39:24 Soutěž Bold Picky s Matty Glamping1:40:44 Rams vs Eagles (SNF, NS2)1:49:15 Chargers vs Ravens (Zápas kola, MNF, NS2)2:00:56 Sázkařské okénko s Fortunou

Utkání v Mnichově nám definitivně odzvonilo celou Evropskou šňůru NFL. Teď už se musíme spokojit pouze ze zápasy ve starých dobrých Spojených státech. Favorité jednotlivých konferencí se nám pomalu ale jistě sice profilují, ale pořád je před námi spousta a spousta kvalitního fotbalu. Dokáže někdo porazit Chiefs nebo si proklestí cestu k perfect season? Zvládnou se ještě Bengals vrátit do sezóny? Spousta dalších otázek bude vyřčeno a doufejme, že i zodpovězeno v tradičním středečním vysílání na našem Youtube kanále od 17:45. Doražte včas! -------------------------------------------- OBSAH: 0:00:09 Úvod0:02:29 Nori novoroční trip do USA0:04:41 Vyhlášení soutěže z živého vysílání0:08:45 Novinky o partnerech NFL.cz0:12:51 Eagles vs Commanders (TNF, NS2)0:21:31 Lions vs Jaguars0:31:40 Titans vs Vikings0:37:15 Dolphins vs Raiders0:42:38 Patriots vs Rams0:49:42 Saints vs Browns0:53:47 Jets vs Colts0:59:35 Komerční intermezzo - poděkování partnerům projektu NFL.cz1:03:35 Bears vs Packers (Derby kola)1:17:24 Steelers vs Ravens (Telly TV zápas kola, NS6)1:28:27 Broncos vs Falcons1:36:48 46ers vs Seahawks1:43:42 Soutěž "Bold Picky" s Matty Glamping1:45:32 Chargers vs Bengals (SNF, NS6)1:51:02 Cowboys vs Texans (MNF, NS6)1:57:39 Bills vs Chiefs (Zápas kola, NS6)2:03:22 Počítání zajáců v sázkařském okénku s Fortunou

Polovina základní části sezóny NFL je bohužel za námi. To ale zatím není důvod propadat smutku a panice. Ještě pořád je před námi spoustu zajímavého a napínavého fotbalu. Desátý hrací týden mimo jiné přinese také utkání v Mnichově, ke kterému podobně jako k prvnímu Londýnskému utkání připravujeme obrovské množství obsahu. Budeme samozřejmě také sledovat, jak se uchytí nový hráči, kteří byli vyměněni těsně před trade deadline. Zkrátka a dobře témat na probrání je obrovská spousta, tak přijďte ve středu od 17:45 na náš youtube. ----------------------------------------------- OBSAH: 0:00:09 Úvod0:01:47 Představení nových partnerů NFL.cz0:13:03 Vyhlášení soutěže z živého vysílání0:16:28 Giants vs Panthers (International Game - Mnichov, NS1)0:23:47 Bears vs Patriots0:33:50 Colts vs Bills0:41:08 Chiefs vs Broncos0:51:38 Saints vs Falcons1:03:16 Buccaneers vs 49ers1:11:12 Commanders vs Steelers (NS6)1:18:54 Komerční přestávka - poděkování partnerům projektu NFL.cz1:23:57 Ravens vs Bengals (Derby kola, TNF, NS2)1:33:53 Jaguars vs Vikings1:41:33 Chargers vs Titans1:48:20 Cowboys vs Eagles (NS6)1:56:56 Soutěž Bold Picky s Matty Glamping2:00:29 Cardinals vs Jets2:09:21 Rams vs Dolphins (MNF, NS2)2:17:53 Texans vs Lions (Zápas kola, SNF, NS6)2:29:09 Sázkařské okénko s Fortunou2:32:35 Závěr

Máme za sebou osmý hrací týden a s ním v podstatě celý měsíc říjen. Zároveň se dostáváme do poloviny základní části a výrazným způsobem se přibližujeme k trade deadline, který nastane 5.11. Ještě předtím je ale potřeba odehrát a pochopitelně i rozebrat devátý hrací týden. Jsou Jets definitivně odsouzeni k neúspěchu? Ztratilo se kouzlo Vikings? Zvedají se Eagles? To jsou jen některé otázky, kterým se pokusíme přijít na kloub v našem tradičním vysílání ve středu 30.10. od 17:45 na našem Youtube. Přijďte za námi živě! -------------------------------------- OBSAH: 0:00:09 Úvod0:00:32 Informační okénko - představení Vito Martini Sports Cards0:04:01 Vyhlášení soutěže z živého vysílání0:06:24 Stanovisko k vysílání zápasů NFL na kanálech Nova Sport0:09:24 Jets vs Texans (TNF, NS2)0:17:44 Falcons vs Cowboys (NS1)0:29:32 Bills vs Dolphins0:34:51 Bengals vs Raiders0:39:59 Browns vs Chargers0:45:24 Titans vs Patriots0:56:53 Ravens vs Broncos1:03:39 Reklamní přestávka - poděkování partnerům projektu NFL.cz1:07:08 Seahawks vs Rams (NFL.cz derby kola)1:15:48 Giants vs Commanders1:23:15 Panthers vs Saints1:33:04 Eagles vs Jaguars1:39:31 Cardinals vs Bears1:50:39 Soutěž s Matty Glamping1:56:20 Vikings vs Colts (SNF, NS1)2:04:49 Chiefs vs Buccaneers (MNF, NS6)2:08:37 Packers vs Lions (Zápas kola, NS1)2:16:07 Sázkařské okénko s Fortunou

Zápas ve Wembley nám ukončil trojdílnou londýnskou sérii. Nebyla to sice žádná velká přehlídka skvělého fotbalu, ale i tak jsme si to všechno parádně užili. O to zajímavější byl televizní zápas mezi Vikings a Lions, ve kterém tedy poprvé v letošním ročníku tým z Minnesoty našel přemožitele. Posledním mohykánem bez negativního zářezu na pažbě zůstává Kansas City Chiefs. Vydrží mu tahle série? Rozjel se někdo k velkému trháku? A asi nejdůležitější otázka osmého hracího týdne, uvidíme očekáváný souboj nováčků Williamse a Danielse? Na tyto, ale i další otázky se pokusíme odpovědět v našem tradičním vysílání ve středu v 17:45! ----------------------------------------- OBSAH: 0:00:09 Úvod0:01:03 Vyhlášení soutěže z živého vysílání0:03:39 Ondrovo otevírací téma o podcastech0:05:24 Rams vs Vikings (TNF, NS5)0:13:23 Browns vs Ravens0:23:29 Lions vs Titans0:32:18 Dolphins vs Cardinals0:38:47 Buccaneers vs Falcons (NS6)0:44:27 Jaguars vs Packers0:48:55 Texans vs Colts0:54:56 Chargers vs Saints0:59:43 Reklamní intermezzo - poděkování donátorům a partnerům projektu NFL.cz1:01:55 Patriots vs Jets (NFL.cz derby kola)1:12:52 Seahawks vs Bills1:17:23 Bengals vs Eagles1:28:21 Broncos vs Panthers1:30:11 Raiders vs Chiefs1:36:11 Soutěž s Matty Glamping1:37:49 49ers vs Cowboys (SNF, NS6)1:42:36 Steelers vs Giants (MNF, NS2)1:47:59 Commanders vs Bears (Zápas kola, NS6)1:53:03 Sázkařské okénko s Fortunou

Sedmý hrací týden přinesl hned ve svém úvodu dva třaskavé přestupy elitních wide-receiverů. Jak tohle ovlivní nadcházející průběh soutěže? Zvládneme rozklíčovat největšího favorita NFC North? Jako vždy nám NFL přináší velkou řadu otázek, ale prahbídně odpovědí. Na druhé straně šestý hrací týden byl zatím tipérsky zdaleka nejzdařilejší. Máme už tedy nějakou představu o favoritech? Vše si probereme tradičně ve středu od 17:35 na našem Youtube. ---------------------------------- OBSAH: 0:00:09 Úvod0:02:30 Vyhlášení soutěže z živého vysílání0:04:40 Soutěže s Matty Glamping0:07:06 Informace o knize Green Bay Packers0:07:56 Saints vs Broncos (TNF, NS5)0:24:44 Jaguars vs Patriots (London International game, NS2)0:34:24 Falcons vs Seahawks0:42:32 Bills vs Titans0:56:37 Browns vs Bengals1:07:10 Packers vs Texans1:21:57 Colts vs Dolphins1:28:17 Reklamní intermezzo - poděkování donátorům a partnerům projektu NFL.cz1:29:46 Giants vs Eagles (NFL.cz derby kola)1:48:11 Rams vs Raiders1:53:36 Commanders vs Panthers1:56:18 49ers vs Chiefs (NS2)2:05:20 Steelers vs Jets (NS2)2:11:30 Buccaneers vs Ravens (MNF, NS2)2:17:19 Cardinals vs Chargers2:25:12 Vikings vs Lions (Zápas kola, NS2)2:33:20 Sázkařské okénko s Fortunou2:36:32 Slovo závěrem

Ať už tomu chcete věřit, nebo ne, čeká nás šestý hrací týden NFL. Máme za sebou první trenérskou změnu a spousta velkého potenciálu přišla vniveč. Na druhé straně Vikings se poprali i s tradičním britským počasím a stále zůstávají neporaženi. Co nám přinese nadcházející kolo? Udělali Jets správný krok? Dává smysl v tuto chvíli startovat Drakea Mayeho? Jako obvykle vše důležité probereme ve středu od 17:45 na našem YouTube. --------------------------- OBSAH: 0:00:09 Úvod0:01:34 Shrnutí ke speciálnímu předzápasovému studiu k zápasu Vikings vs Jets v Londýně0:04:35 Noriho informační okénko0:07:46 Seahawks vs 49ers (TNF, NS6)0:16:06 Bears vs Jaguars (International game, NS1)0:27:28 Packers vs Cardinals0:33:26 Titans vs Colts0:43:17 Patriots vs Texans0:53:32 Saints vs Buccaneers0:59:27 Eagles vs Browns1:08:41 Poděkování donátorům a partnerům projektu NFL.cz1:10:46 Broncos vs Chargers (NFL.cz derby kola)1:20:05 Ravens vs Commanders (NS1)1:30:54 Raiders vs Steelers1:40:46 Panthers vs Falcons1:51:03 Giants vs Bengals (SNF, NS6)1:58:43 Jets vs Bills (MNF, NS2)2:20:51 Cowboys vs Lions (NS1)2:28:00 Sázkařské okénko s Fortunou

Poseł PiS Maciej Wąsik mówi w Poranku Wnet, że w budżecie nie ma pieniędzy na kosztujący 10 mld zł program Tarcza Wschód, który zapowiada premier Donald Tusk. Na razie to deklaracja wyborcza – dodaje. Kandydujący do Parlamentu Europejskiego polityk deklaruje poparcie dla wszystkich działań rządu, zmierzających do realnego wzmocnienia bezpieczeństwa Polski. Jednak, jak zauważa, póki co są to tylko zapowiedzi. „Tak wiarygodne, jak benzyna po 5,19 zł czy kwota wolna 60 tys. zł” – tłumaczy Wąsik. Premier Donald Tusk zapowiedział w sobotę w Krakowie realizację programu „Tarcza Wschód”, który miałby na celu rozbudowę infrastruktury na granicy wschodniej, która pozwoliłaby zatrzymać ewentualną agresję rosyjską i białoruską. „Te 10 mld zł uruchomiliśmy już w tej chwili” – mówił Tusk. Maciej Wąsik komentując słowa premiera zwraca uwagę, że pieniędzy na nowy program nie przewidziano w budżecie państwa. Budżet trzeba by znowelizować, na razie to są deklaracje wyborcze. Dotychczas jedyny konkret z tym związany to „bannerki” Platformy Obywatelskiej – stwierdza polityk Prawa i Sprawiedliwości. Wąsik podkreśla hipokryzję konkurencyjnej partii. Wylicza sprzyjające Rosji posunięcia PO z przeszłości. Brak sprzeciwu rządu PO wobec budowy gazociągu NS2, wypowiedź Sikorskiego o Rosji w NATO, otworzenie małego ruchu granicznego z Kaliningradem, reset, „nasz człowiek w Warszawie” – mówi. Z drugiej strony, jak podnosi Wąsik, „to rząd PiS pierwszy wsparł poważnymi środkami Ukrainę w walce Rosją, to my odparliśmy atak hybrydowy z Białorusi”. Pytany o twierdzenie gen. Piotra Pytla, byłego szefa SKW o możliwym zamachu na premiera Donalda Tuska, Maciej Wąsik ocenia je jako „wrzutkę polityczną” Gdyby takie informacje były prawdziwe, Pytel wykazałby się nieodpowiedzialnością, nagłaśniając je w taki sposób – mówi Wąsik. W sprawie wyników eurowyborów dla Prawa i Sprawiedliwości Maciej Wąsik jest optymistą. Twierdzi, że „społeczeństwo jest zmęczone ciągłymi obietnicami Donalda Tuska”. Polacy zaczęli już przeglądać na oczy, że zostali oszukani i przez Tuska, i przez Trzecią Drogę, która okazała się być trzecią… nogą Donalda Tuska. Ludzie dadzą temu wyraz albo idąc i głosując na PiS, albo nie idąc na wybory i nie oddając głosu – przewiduje polityk PiS.

Rocket City meets Music City as we talk with Olivia Christian, Marketing Director for tvg hospitality – a hospitality group that focuses on fan and artist experiences. Olivia tells us all about tvg's flagship and first U.S. venue, The Orion Amphitheater in Huntsville, AL, which is an 8,000 capacity greek-inspired amphitheater which opened in spring 2022. In addition to hosting many national touring shows, the venue focuses on being the “third space” for people (after home and work) with a huge focus on community and cultural events, sustainability practices, and hospitality for everyone visiting. The venue's focus on sustainability includes zero waste to landfills, a reusable cup program (reused over 500,000 cups since opening!), and allowing water bottles with water stations throughout the venue. They also have an artist garden with fruits, vegetables, and herbs that are used as garnish for drinks and used in food as well as a special bar named “Carbon” which donates $1 from every purchase to Tennessee Riverkeeper to protect rivers by enforcing environmental laws and educating the public. We chat with Olivia about her history in live events, which includes runs at Ryman Auditorium, War Memorial Auditorium, Tennessee Performing Arts Center, and promoter National Shows 2 (NS2). Enjoy this fun, informative episode that's sure to inspire you to follow your passion, buck venue stereotypes, and have a greater appreciation for a good marketing mix.Olivia Christian: LinkedIn | Emailtvg hospitality: Facebook | Instagram | LinkedInThe Orion Amphitheater: Facebook | Instagram ––––––ADVENTURES IN VENUELANDFollow on Instagram, LinkedIn, Facebook, or X/TwitterLearn more about Event & Venue Marketing ConferenceMeet our team:Paul Hooper | Co-host, Booking, Branding & MarketingDave Redelberger | Co-host & Guest ResearchMegan Ebeck | Marketing, Design & Digital AdvertisingSamantha Marker | Marketing, Copywriting & PublicityCamille Faulkner | Audio Editing & MixingHave a suggestion for a guest or bonus episode? We'd love to hear it! Send us an email.

STORY EPISODE – Joyous holiday season Venuelanders! As we prepare for an exciting 2024 with some incredible guests and bonus episodes, please enjoy this special holiday treat. Here is our version of that classic, fire-side story which will hopefully warm your heart – ‘Twas the Night Before Show Day.

On this episode, Caroline Donaghue and Priya Rawal welcome the first sportsman to the episode, Simon Shaw MBE. Simon is a prominent former England rugby union player, current Head of Sustainable Technology Partnerships for NS2, and President of charity, Love of the Game.Simon had an idyllic childhood in Nairobi until his family had to flee from a volatile political election, his family suddenly moved to Gainsborough for a short while before relocating to Madrid. These sudden changes in his youth prepared Simon for an equally storied career. At age 15, Simon started his career in rugby and he maintained a successful career in professional rugby, during which he played for the biggest teams in rugby: Bristol, London Wasps and Toulon. He was part of the winning World Cup team in 2003, winning 71 caps for England between 1996 and 2011 and 2 for the British & Irish Lions. Since retiring from the sport, Simon has reinvented himself in the business world, working in both sustainable technology and hospitality sector while simultaneously founding his own charity, Love of the Game which aims to tackle concussion in sports.This is an episode where Simon reflects on the magnitude of his rugby tours, the glory years at Wasps, playing alongside the world's greatest players at and never giving up.Sponsored by V1 & The Luxury Property Forum. Follow Caroline @caroline.donaghue and Priya @priya.rawal.london and the podcast page @therealrendezvous on Instagram and LinkedIn. Produced by BBE Podcast Agency. #therealrendezvous #simonshaw #rugbyunion #londonlions #professionalrugby #retiredsportsman #londonwasps #rugbyplayer Hosted on Acast. See acast.com/privacy for more information.

With Nina Müller, Ethical Commerce Alliance Director and host of the Ethical Allies podcast. __ This was a pretty active season in terms of regulatory updates and decisions or guidelines coming out of supervisory bodies:  Spain's AEPD issued a decision on the use of Google Analytics by the Royal Academy of Spanish Language (“RAE”), becoming the first EU Data Protection Agency to see the glass half full in the use of the widespread digital data collection service (having been considered high-risk in Denmark, Italy, France, the Netherlands and Austria). It must however be noted that the RAE was only using the most basic version of the tool, without any AdTech integrations or individual user profiling - and in this regard aligned with the CNIL's long-standing guidelines for the valid use of the tool. At EU level, the Artificial Intelligence Act (which we have covered this quarter in a couple of Masters of Privacy interviews) made fast progress with the Council adopting its final position. At the same time, new common rules on cybersecurity became a reality with the approval of the NS2 Directive (or v2 of the Network and Information Security Directive) on November 28th. The updated framework covers incident response, supply chain security and encryption among other things, leaving less wiggle room for Member States to get creative when it comes to “essential sectors” (such as energy, banking, health, or digital infrastructure). Across the Channel, the UK's Data Protection Agency (ICO) issued brand new guidelines on international data transfers, providing a practical tool for businesses to properly carry out Transfer Risk Assessments and making it clear that either such tool or the guidelines provided by the European Data Protection Board will be considered valid.  Already into the new year, the European Data Protection Board (EDPB) issued two important reports, on valid consent in the context of cookie banners (in the hope to agree on a common approach in the face of multiple NOYB complaints across the EU) and the use of cloud-based services by the public sector. The former concluded that the vast majority of DPAs (Supervisory Authorities) did not accept hiding the “Reject All” button in a second layer - which most notably leaves Spain's AEPD as the odd one out. They did all agree on the non-conformity of: a) pre-ticked consent checkboxes on second layer; b) a reliance on legitimate interest; c) the use of dark patterns in link design or deceptive button colors/contrast; and d) the inaccurate classification of essential cookies. The latter concluded that public bodies across the EU may find it hard to provide supplementary measures when sending personal data to a US-based cloud (as per Schrems II requirements) in the context of some Software as a Service (SaaS) implementations, suggesting that switching to an EEA-sovereign Cloud Service Provider (CSP) would solve the problem and getting many to wonder whether it also refers to US-owned CSPs, which would leave few options on the table and none able to compete at many levels in terms of features or scale.  All of which can easily lead us to the latest update on the EU-US Data Privacy Framework: The EDPB released its non-binding opinion on the status of the EU-US Data Privacy Framework (voicing concerns about proportionality, the data protection review court and bulk data collection by national security agencies). The EU Commission will now proceed to ask EU Member States to approve it with the hope of issuing an adequacy decision by July 2023. This would do away with all the headaches derived from the Schrems II ECJ decision (including growing pressure to store personal data in EU-based data centers), were it not for the general impression that a Schrems III challenge looms in the horizon. In the United States, long-awaited new privacy rules in California (CPRA) and Virginia (CDPA) entered into force on January 1st. Although both provide a set of rights in terms of ensuring individual control over personal data being collected across the Internet (opt-out, access, deletion, correction, portability…), California's creates a private right of action that could pave the way for a new avalanche of privacy-related lawsuits.In any case, only companies meeting a minimum threshold in terms of revenue or the amount of consumers affected by their data collection practices (both of them varying across the two states) will have to comply with the new rules. Lastly, Privacy by Design will become ISO standard 31700 on February 8th, finally introducing an auditable process to conform to the seven principles originally laid out by Anne Cavoukian as Ontario(Canada)'s former Data Protection Commissioner.    Enforcement updates It's been interesting to see how continental Data Protection Agencies (“DPAs”) keep milking the cow of the ePrivacy Directive's lack of a one-stop-shop for US or China-based Big Tech giants. The long-awaited ePrivacy Regulation never arrived to keep this framework in sync with the GDPR (which does have a one-stop-shop), and this leaves an opening for any DPA to avoid referring large enforcement cases involving such players to the Irish Data Protection Commissioner (“DPC”) whenever cookie consent is involved. This criterion has been further strengthened by the recent conclusions of EPDB cookie banner task force. Microsoft was the last major victim of this particular gap (following Meta and Google), receiving a 60-million euro fine from France's DPA (CNIL), which shortly after honored TikTok with a 5m euro fine (once again, due to the absence of a “Reject All” button on its first layer - or “not being as easy to reject cookies as it is to accept them”) and, not having had enough, went on to give Apple an 8m euro fine for collecting unique device identifiers of visitors to its App Store without prior consent or notice, in order to serve its own ads (which is akin to a cookie or local storage system when it comes to article 5.3 of the ePrivacy Directive).  The CNIL ePrivacy-related enforcement spree did not stop short at Big Tech. Voodoo, a leader in hyper-casual mobile games, was also a target, receiving a 3 million euro fine for lack of proper consent when serving an IDFV (unique identifier “for vendors”, which Apples does allow app publishers to set when IDFA or cross-app identifiers have been declined via the App Tracking Transparency prompt).  Putting the ePrivacy Directive aside, and well into pure GDPR domain, Discord received a 800k euro fine (again, at the hands of CNIL) on the basis of: a) a failure to properly determine and enforce a concrete data retention period; b) a failure to consider Privacy by Design requirements in the development of its products; c) accepting very low security levels for user-created passwords; and d) failing to carry out a Data Protection Impact Assessment (given the volume of data it processed and the fact that the tool has become popular among minors).  And yet, one particular piece of news outshined mostly everything else in this category: Ireland's DPC imposed a 390 euro fine on Meta following considerable pressure from the EDPB for relying on the contractual legal basis in order to serve personalized advertising - itself the core business model of both social networks. We had a debate on the matter with Tim Walters (English) and Alonso Hurtado (Spanish) on Masters of Privacy, and published an opinion piece on our blog.  This last affair is a good segue into Twitter's latest troubles. Its new owner, Elon Musk, not content with having fired key senior executives in charge of EU privacy compliance (including its Chief Privacy Officer and DPO), has suggested that he will oblige its non-paying users to consent to personalized advertising. The Irish DPC (once again, in charge of its supervision under the one-stop-shop rule) asked Twitter for a meeting in the hope to draw a few red lines.  Meanwhile, the Spanish AEPD, still breaking all records in terms of monthly fines, sanctioned UPS (70,000 euros) for handing out a MediaMarkt (consumer electronics) delivery to a neighbor, thus breaching confidentiality duties. This will have a serious impact on the regular practices of courier services in the country.  Back in the United States, Epic Games and the FTC agreed to a $520m fine for directly targeting children under the age of 13 with its Fortnite game (a default setting that allows them to engage in voice and text communications with strangers has made it worse), as well for using for “dark patterns” in in-game purchases. Separately, in what we believe it is a first case of its kind, even in the EU (with the ECJ FashionID case possibly being the closest we have been to it). Betterhelp has received an FTC $7,8m fine for using the Facebook Lookalike Audiences feature (and alternative offerings in the programmatic advertising space, including those of Criteo, Snapchat or Pinterest) to find potential customers on the basis of their similarity with the online mental health service's current user base. This involved sensitive data and follows repetitive disclaimers by Betterhelp that data would in no case be shared with third parties.   On the private lawsuits front (especially important in the US), Meta agreed to pay $725m after a class action was brought in California against Facebook on the back of the ever-present Cambridge Analytica scandal. Also, the Illinois Biometric Information Privacy Act (BIPA) kept putting money into the pockets of claimants and class action lawyers, in this case forcing Whole Foods (an upscale organic food supermarket chain owned by Amazon) to settle for $300.000 - we have previously previous cases against TikTok, Facebook or Snapchat, albeit it was the monitoring, via “voiceprints”, of its own employees (rather than its customers) that triggered this particular lawsuit. Legitimate Interest strikes back  To finish with this section, very recent developments justify turning our eyes back to the UK and the EU as there is growing momentum for the acceptance of the legitimate interest as a legal basis for purely commercial or direct marketing purposes:  While the CJEU decides on a question posed by a Dutch court in January, in which the DPA issued a fine to a tennis association for relying on legitimate interest to share member details with its sponsors (who then sent commercial offers to them), a UK court (First-Tier Tribunal) has ruled against the ICO (UK DPA) and in favor of Experian (a well-known data broker) for collecting data about 5.3m people from publicly available sources, including the electorate register, to build customer profiles and subsequently selling them to advertisers. Experian has relied on legitimate interest and found it too burdensome to properly inform every single individual (this being the ICO's main point of contention). The decision does appear to indicate that using legitimate interest would not be possible if the original data collection had been based on consent, but even this is not entirely clear. So, just to make it even more clear and simple, the UK Government presented a new draft of a new UK Data Protection Bill on March 8th that includes a pre-built shortcut to using legitimate interest without need for the so-called three part test (purpose, necessity, balancing). Data controllers can now go ahead with this legal basis if they find their purpose in a non-exhaustive list provided - which includes direct marketing.  Competition and Digital Markets Google was sued by the Department of Justice for anti-competitive behavior in its dominance of the AdTech stack across the open market (or the ads that are shown across the web and beyond its own “walled gardens”), using its dominance of the publisher ad server market (supply side) to further strengthen its stranglehold of the demand side (advertisers, many of them already glued to its Google Ads or DV360 platforms in order to invest in search keywords or YouTube inventory) and, worse, artificially manipulating its own ad exchange to favor publishers at the expense of advertisers - thereby reinforcing the flywheel, as digital media publishers found themselves with even less incentives to work with competing ad servers.  Zero-Party Data and Future of Media (The piece of news below obliges us to combine both categories this season) The BBC has rolled out its own version of SOLID pods to allow its own customers to leverage their own data (exported from Netflix, Spotify, and the BBC) in order to obtain relevant recommendations while staying in full control of such data. Perhaps a little step towards individual agency, but a giant one for a digital media ecosystem mostly butchered by the untenable notice-and-consent approach derived from the current legal framework - which takes us back full circle to Elizabeth Renieris' new book.  

Remdami mus Patreon matysite PILNUS epizodus ir laidas, taip pat turėsite priėjimą prie labai didelio archyvo. Ačiū. Patreon: https://www.patreon.com/baciulisirramanauskas PILNO EPIZODO TEMOS: 00:00:00 Bachmuto skerdynių prasmė 00:05:26 Kada žadamas UA puolimas? 00:16:41 JAV atnaujino branduolinį atgrasymą 00:29:46 Branduolinė rusų korta – ar dalyvausime žaidime? 00:44:49 Gandai apie NS2 sprogdinimą 00:51:50 Vokiečių lenciūginė Šakalienė Mes būsime labai dėkingi jei pranešite miestui ir pasauliui apie mūsų Patreon: https://www.patreon.com/baciulisirramanauskas Mūsų Facebook: https://www.facebook.com/Ba%C4%8Diulis-ir-Ramanauskas-261379194566105/ Radioshow ir SSG platinami čia: https://www.youtube.com/user/whatlooksrightisrigh/videos Algis & Justas platinami čia: https://www.youtube.com/channel/UCj2SYwpifggjRONErb8Ws_g/videos?view_as=subscriber

Apparently we are shooting down whatever we see up there in the sky.Detailed report on how the US Navy took out NS2.Hazmat nightmare in East Palestine, OhioCheckout https://poweredportablesolar.comMy freeze dryer is running non stopSupport the showHave a question, suggestion or comment? Please email me at practicalpreppodcast@gmail.com. I will not sell your email address and I will personally respond to you.

021423 Podcast, Biden Blew up NS2, Damar Hiding Causality, Holographic Espionage Psyops

According to Don Lemon of CNN hurricane Ian is a new phenomenon. He said this as he scolded Jamie Rhome, acting director of NOAA's National Hurricane Center, for telling him he was wrong about Ian's strength having no relation to climate change. According to the New York Times Ian is the first major hurricane to hit Tampa in over a century, but this is so provably wrong it makes the story totally fictitious. Hurricane wind speed, sustained wind speed, pressure, storm surge, and economic damage, all are weighed, and then the worst condition is selected to create a narrative about the storm. Ian is not hitting Tampa head on, in terms of eye-wall. Joe Biden then warned the public that the best was to prepare for these major storms was to get a ‘shot'. Likewise, when the Nord Stream pipelines were blown up earlier this week the white House told us it was a great opportunity to go ‘green' and the same was said about rising gas prices. But there is more to the story. Just as technology exists to control, intensify, and denitrify hurricanes officially, the pipeline explosions were likely not accidental. Joe Biden and Victoria Nuland both warned that if Russia entered Ukraine the Nord Stream pipelines, particularly NS2, would be dealt with. A few months after Russia ‘invades' we find the US Navy and NATO conducting an unmanned underwater exercise in the Baltic sea near Nord Stream! Another US naval exercise was taking place in the Baltic Sea at the beginning of September. Then the CIA informed Berlin of a coming attack just days before the pipes depressurized from explosions, according to seismographs, and the very day Norway and Poland opened a new gas pipeline to replace Nord Stream 1 and 2. Meanwhile, the largest produce market in the world, Rungis International Market in Paris, has gone up in flames alongside of the dozens of food facilities over the last year that have also burned, exploded, or been hit by planes. Energy and food are under sustained attack. If United States did blow up the pipelines, it is an act of terrorism and war on Russia and Germany, which had control of the project.

Kontrofensywa Ukrainy, orędzie Władimira Putina, rosyjskie groźby użycia broni atomowej, niepokojące ruchy na terenie Białorusi, wybuchy i wycieki z NS1 i NS2 - o tym wszystkim w najnowszym odcinku Miesięcznika Zagranicznego Nowej Konfederacji! Udział w dyskusji biorą: Jerzy Marek Nowakowski, Marek Budzisz, Bartłomiej Radziejewski. W roli prowadzącej red. Jaśmina Nowak.

Überblick: Energiepreise, Druckabfall NS1 und NS2, Speicherfüllstand über 90 %, Wirtschaftlicher Abwehrschirm gegen die Folgen des russischen Angriffskriegs, Gasumlage kommt nicht, Bund übernimmt 99% von Uniper, AKW Laufzeit, Rosneft Deutschland GmbH - Treuhandschaft, Scholz im Ausland, Neues EU Maßnahmenpaket gegen Russland als Reaktion auf die Scheinreferenden, Sicherheitsplattform geht online, Wärmepumpenampel - Ist euer Haus Wärmepumpen geeignet?, Lesetipp: Agora-Studie - Schutz in der fossilen Energiekrise Spezifizierung: Rosneft Deutschland GmbH wurde unter die Treuhandschaft des Bundes gestellt. In der Folge wurde pauschal nur Rosneft genannt. Hier war nicht der russische Mutterkonzern gemeint. Kontakt: Twitter (redispatch_pod), LinkedIn (Redispatch), Instagram (Redispatch_Podcast), TikTok (redispatch) Agora Energiewende (2022): Schutz in der fossilen Energiekrise BMWK (2022): Wirtschaftlicher Abwehrschirm gegen die Folgen des russischen Angriffskrieges FfE (2022): Wärmepumpen-Ampel THE, Bundesnetzagentur (2022): Sicherheitsplattform Gas

ORN Patrick Timpone show notes 9/28/22 Scheduled guest Martin Armstrong is now evacuating his home in Florida due to Hurricane Ian. The lucrative banking industry - making money by making money for a living. Imminent banking crisis starting in Europe and then spreading to the US next year. Sovereign debt crisis will explode in Europe. Promoted by the obsoletes, Patrick's new term for the elites. Too Big To Fail movie about banking-caused 2007 implosion covered over by TARP. It was not caused by subprime mortgages. Long US history of banks running things and causing turmoil. Is this the big one, the one the crashaholics have long warned is coming? Spiritual and emotional shifts going on. Communism, gender confusion, transhumanism, climate change, COVID - It's all been a lie. Is the CIA or another US agency behind the Monday's Nordstream 1 and 2 explosions? They're trying to make everything worse. NS1 and NS2 pipelines are very deep in the ocean. Sabotage probably required a submarine. Charles Nenner doesn't recommend being in equity markets until October or November. Dollar still very strong because other currencies are in worse shape. Dollar Index won't go much higher. Don't give energy to physical complaints. What we resist persists. Patrick's pain in the bladder area went away 2 months after being on an animal based diet. Temps staying up without thyroid now. Is meat the species appropriate diet for humans? The technology of X3. Building muscle with bands- the safest, quickest way to build muscle without getting sore. Never losing pressure is key. Different technology than lifting weights. Repetitively stretching a band with ever decreasing excursions until you can't move. What will currency change to? Choosing not to participate in what's coming. Hurricane Ian - catastrophic strike this am at west coast of Florida, but winds will expand to the east coast of FL. 2nd landing to come on s.e. coast of Florida on Friday. Listener trying to go carnivore, but overwhelming sugar urges on 3rd day. Drinking orange juice to satisfy those cravings. The more sugar you do, the more you want it. Listener's mother suffering with colorectal cancer. In pain and is wasting away. Try bone broth, meat, and fat. Listener not sure they can live without baked potato and pasta. They are comfort foods and wind up being a drug. Compare the feeling after eating pasta to after eating meat. Listener misses Richard Maybury shows. He's taking a break. Stanley Druckmiller – predicts hard landing by end of 2023. Coming recession or worse. Every Fed hiking cycle ends in default and bankruptcy of government. Massive QE of $30 trillion is fueling the recession. We're in deep trouble. Most severe Fed tightening since 1980. The Fed is causing the issues and they know it. Raising increase rates won't stop inflation. 11 year lows on home sales. Will the US be the Weimar Republic or Venezuela? Martin Armstrong found documents showing plans made during Clinton Administration to overthrow Russia. 2 more days on Surthrival Chaga/Reisha 20% off sale.

According to Don Lemon of CNN hurricane Ian is a new phenomenon. He said this as he scolded Jamie Rhome, acting director of NOAA's National Hurricane Center, for telling him he was wrong about Ian's strength having no relation to climate change. According to the New York Times Ian is the first major hurricane to hit Tampa in over a century, but this is so provably wrong it makes the story totally fictitious. Hurricane wind speed, sustained wind speed, pressure, storm surge, and economic damage, all are weighed, and then the worst condition is selected to create a narrative about the storm. Ian is not hitting Tampa head on, in terms of eye-wall. Joe Biden then warned the public that the best was to prepare for these major storms was to get a ‘shot'. Likewise, when the Nord Stream pipelines were blown up earlier this week the white House told us it was a great opportunity to go ‘green' and the same was said about rising gas prices. But there is more to the story. Just as technology exists to control, intensify, and denitrify hurricanes officially, the pipeline explosions were likely not accidental. Joe Biden and Victoria Nulled both warned that if Russia entered Ukraine the Nord Stream pipelines, particularly NS2, would be dealt with. A few months after Russia ‘invades' we find the US Navy and NATO conducting an unmanned underwater exercise in the Baltic sea near Nord Stream! Then the CIA informed Berlin of a coming attack just days before the pipes depressurized from explosions, according to seismographs, and the very day Norway and Poland opened a new gas pipeline to replace Nord Stream 1 and 2. Meanwhile, the largest produce market in the world, Rungis International Market in Paris, has gone up in flames alongside of the dozens of food facilities over the last year that have also burned, exploded, or been hit by planes. Energy and food are under sustained attack.

Nord Stream Pipeline HEADLINE: Germany and EU Have Been Handed Over a Declaration of War by Pepe Escobar  The pipes on both NS and NS2 can be repaired, of course, but hardly before the arrival of General Winter. The question is whether Gazprom – already focused on several hefty Eurasian customers – would bother, especially considering that Gazprom vessels could be exposed to a possible NATO naval attack in the Baltic.  As if all of that was not serious enough, Germany is contractually obligated to purchase at least 40 billion cubic meters of Russian gas a year until 2030. QUESTION: Remember when Donald Trump told them NOT to do this? Just say no? They can't: Gazprom is legally entitled to get paid even without shipping gas. That's the spirit of a long-term contract. And it's already happening: because of sanctions, Berlin does not get all the gas it needs but still needs to pay. If you could get bacon back in WWI they asked you to save your bacon fat for the nitrates b/c they used it to make bombs.

On this second of three "From the Archives" specials, The New Diplomatist is proud to present a never-before-released episode from May 20th of 2022 with Paul J. Saunders, discussing a fascinating look at Russia relations, Euro geopolitics, Russia-China cooperation, and Russian energy after Biden's NS2 green light. In the sweeping conversation, Paul and Garrison outline the strategic thinking of the West post-Cold War but before the dawn of the new Ukraine conflict, a invaluable time capsule view of what was, what could have been, and what has since become reality. Paul J. Saunders is the President of the Energy Innovation Reform Project and a Senior Fellow in U.S. Foreign Policy at the Center for the National Interest. His current work focuses on U.S.-Russia relations, America's role in an evolving international system, and energy and climate change. Until January 2019, he was Executive Director and Chief Operating Officer of the Center for the National Interest and a member of the Center's Board of Directors. He also directed the Center's U.S.-Russian Relations Program in addition to leading projects on other issues, including energy and climate change and U.S.- Japan relations, and served as Associate Publisher of the foreign policy magazine The National Interest, published bi-monthly by the Center for the National Interest. Mr. Saunders served in the Bush Administration from 2003 to 2005 as Senior Advisor to the Under Secretary of State for Global Affairs. In that capacity, he worked on a broad range of transnational issues, in particular with respect to Russia, Ukraine, and the former Soviet Union, as well as Iraq, China and India. Earlier, Mr. Saunders served as Director of the Center from 1997 to 2003, and was Assistant Director of the Center from its founding in 1994 until 1997. In 2000, he was a Senior Policy Advisor to the Speaker's Advisory Group on Russia, established by the Republican Policy Committee of the U.S. House of Representatives. He has written extensively for major newspapers and journals, and is a frequent commentator in national media, including CNN, Fox, and MSNBC. Mr. Saunders is the editor of A New Direction in U.S.-Russia Relations? America's Challenges & Opportunities in Dealing with Russia; Costs of a New Cold War: The U.S.-Russia Confrontation over Ukraine and Enduring Rivalry: American and Russian Perspectives on the Former Soviet Space and the author of works including Extended Deterrence in a Changing Asia; Russian Energy and European Security; and Russia and the Greater Middle East: Challenges and Opportunities (with Geoffrey Kemp). You can follow him on Twitter @1796Farewell. Garrison Moratto is the founder and host of The New Diplomatist Podcast; he earned a M.S. of International Relations as well as a B.S. in Government: Public Administration (Summa Cum Laude) at Liberty University in the United States. Guest opinions are their own.

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What do national defense, commercial innovation, artificial intelligence, bad ass drones, and VR goggles all have in common?  Yes, they are all tech we might trust.  But, if you answered “Palmer Luckey, the inventor and entrepreneur”, we would be so happy – and impressed.  In this episode we recast a chat with Palmer, from our innovation garage, – to talk about… innovation.   Palmer has challenged the defense industrial base to innovate better and faster.  We'll dig into machine learning, sensor fusion, the struggle for world domination, and why jumping directly from high school to the world of high tech may be a great approach for people who want to make a difference. Speakers:Palmer Luckey, Founder, Anduril IndustriesGreg Reeder (host) - VP of Marketing for NS2

In this episode we take a deep dive with two experts in the field of IT and innovation – Tim Hoechst and Nick Sinai. We cover a lot of ground – from policy to perspectives on what it means to tackle cyber security, through Zero Trust.  We also welcome a new character to the show – Dr. Decoder.  If you've ever been in a meeting where the acronyms fly around a bit too much, you need a guy who can break down all the terms, Barney-style.  Our Dr. Decoder is that guy.  Listen in for his “interruptions” and some good scoop on how NOT trusting can be a good thing.Speakers:Nick Sinai - Senior Advisor/Venture Partner, Insight PartnersTim Hoechst - Chairman, NS2 Advisory BoardGreg Reeder (host) - VP of Marketing for NS2Brian Paget (host) - CSO of NS2

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In this week's European energy market podcast Jeremy Nicholson talks to Alfa's Dr Petra Puskarova about the continuing issues with gas and power prices and the demand destruction resulting in some quarters.In this week's Resonance you will learn:Will NordStream 2 (NS2) come to the rescue this winter, and will Norway offer further relief to high pricesDemand destruction rears it head as companies determine that current conditions are inoperableGas storage levels and the challenges for winter aheadThe risk if NS2 is not commissionedWhile Europe sustains high energy costs, Asia remains higher stillPower propped up by gas and coalEuropean energy security back on the agendaThe current situation impacting energy suppliersCarbon is not the headline; some sell off possible if industrial activity gets impacted by high gas prices.

In this week's UK energy market podcast we talk to Alfa's Jason Durden about gas prices remaining high, supporting power prices and Europe's reliance on coal and the asset bubble propping up commodity costs.In this week's Resonance you will learn:Why it's more than supply chains and opportunism driving sustained energy commodity price rises Does loose monetary and fiscal policy mean more of the same for energy buyers?Oil turbulence causes a storm, but has it run out of steam?How the politics of NS2 is supporting high prices in gas for nowWhy coal fired electricity generation remains a critical source of power and a sign of the times as we head towards the COP26 summit.

In this week's UK European energy market podcast we talk to Alfa's Dr Petra Puskarova about volatility in energy prices while gas prices remain high.In this week's Resonance you will learn:A correction in oil prices, when and on what basis that might happenWhy high gas prices in Asia impact EuropeWhen to expect the first gas flows from NS2 and how recent news, although incorrect, impacted pricesWhat the combination of gas, carbon and coal market dynamics are doing to power prices. What the main drivers are and how future developments could impact powerIs holiday season peaking adding some premium outside of main hubs?With lower cooling demand and for example a lack of challenges to the French nuclear fleet this year with more moderate temperatures compared to 2020, why is there a premium in the market right now?

W ramach umowy Niemcy mają zainwestować w ukraiński sektor energetyczny, zobowiążą się do sankcji w razie wrogich działań Rosji i wesprą Inicjatywę Trójmorza. Zdaniem Jakuba Wiecha, który był gościem Piotra Pogorzelskiego, w podcaście Po prostu Wschód  już samo uruchomienie gazociągu jest bronią polityczną - zmienia bowiem już teraz architekturę dostaw gazu ze Wschodu na Zachód. Porozumienie Berlina i Waszyngtonu jest zwycięstwem Moskwy i zmniejsza wiarygodność Stanów Zjednoczonych w Europie Środkowej i Wschodniej. Według zeszłotygodniowej deklaracji, Niemcy mają również stworzyć Zielony Fundusz dla Ukrainy w celu "wsparcia transformacji energetycznej Ukrainy, wydajności energetycznej i bezpieczeństwa energetycznego". Berlin ma wpłacić co najmniej 175 mln dolarów i wspólnie z Waszyngtonem wspierać i promować inwestycje warte co najmniej 1 miliard dolarów. Jednak, jak podkreśla zastępca redaktora naczelnego Energetyki 24, ta suma jest wyjątkowo mała w porównaniu z wpływami ukraińskiego budżetu z tranzytu rosyjskiego paliwa. Więcej o tym, jak uruchomienie Nord Stream 2 zmieni rynek gazu w Europie, w podcaście Piotra Pogorzelskiego. Rozmowa została udostępniona bezpłatnie w ramach współpracy pomiędzy autorem podcastu i portalem Nowa Europa Wschodnia. Projekt "Po prostu Wschód" można wesprzeć na Patronite.  

Wasyl Bodnar komentuje porozumienie Angeli Merkel i Joe Bidena ws. budowy Nord Stream 2. Stany Zjednoczone dały zielone światło na budowę gazociągu. W ramach umowy USA wstrzymują nakładanie sankcji na NS2, zaś Niemcy zainwestują w ukraińskie projekty i zobowiążą się do sankcji w razie wrogich działań Rosji. Wiceszef ukraińskiego MSZ krytykuje oba państwa. Uważa inwestycję za zagrożenie dla polityki energetycznej krajów Europy i Środkowej. Ukraina zamierza bojkotować to porozumienie. Bodnar mówi również na temat konferencji 23 sierpnia (Platforma Krymska), na której będzie omawiany problem przyszłości anektowanego przez Rosję Krymu. --- Send in a voice message: https://anchor.fm/radiownet/message

Gas supply challenges look more settled as we approach August, but the challenges faced by renewable power generation and the need to offset fluctuations with on-demand supplies put an upward pressure on electricity supply costs. In this episode of the Resonance podcast, you will learn:NS2 expected into Europe early in 2022. Why access to gas in Europe for the U.K. mattersGas - A return to steady LNG supplies more likely in August, and some key maintenance for gas infrastructure coming to an end means we expect to see an improvement in supplySustained period of oil bullishness coming to an end? OPEC signals increased production, compounded by market caution over economies attempting to reopen, as the UK's Freedom Day signals an end to lockdown.While the Impact of decarbonisation sees the U.K. carbon market quite settled, and the Cost Containment Mechanism (CCM) within the scheme may be triggered in August for the first time. What is it, how and will it control costs?Fluctuations in wind power generation are still having an acute impact on power prices. What does that mean for prices and generation mix? Can we achieve what we need to without seeing the rolling blackouts familiar to businesses operating in California, where decarbonisation without a managed approach is causing challenges? A greater dependence on imports are proving problematic for the U.K. and power prices now we are outside of the EU, but why?

Leslie Palti Guzman exchanged with Anna Mikulska on European pipeline politics and the use of natural gas as a geo-economic tool. They spiced up their discussion on Russia's Nord Stream 2 pipeline (NS2) by looking at statements advanced by the advocates and opponents of the project and gave their insights on why it's false, true or more nuanced. This is a timely topic with geopolitical ramifications; natural gas is here to stay in Europe for a few decades so it's important to understand what is at stake with NS2. Anna is also sharing what shaped her analytical mind and interest on energy issues from her Polish background to her law studies. This episode was recorded on Apr. 30, 2021.

SAP NS2's CEO, Mark Testoni, joins Coruzant Technologies for the Digital Executive podcast. He shares how NS2 was created as an independent subsidiary of SAP yet still provides SAP's great technology to the market. Most notably, they they stood up NS2 Labs where they brought their customers and partners together to solve problems using technology.

Dr Szymon Kardaś o stosunku Rosji do zablokowaniu projektu Nord Stream 2. Według naszego gościa Rosjanie uważają, że budowa rurociągu w przyszłości zostanie dokończona. Tak więc nie patrzą negatywnie na obecny sprzeciw USA. Ponadto dla interesów Gazpromu nie jest na razie istotna budowa NS2. Moce przesyłowe spółki nie są na razie wystarczalne, aby eksportować dostatecznie dużo gazu. Ponadto pandemia koronawirusa spowodowała, że zapotrzebowanie na ten rodzaj energii jest o wiele mniejsze. Zatrucie zaś Aleksieja Nawalnego postrzega jako sygnał w stronę opozycji. Ma on podkreślać wielkość władzy Władimira Putina. --- Send in a voice message: https://anchor.fm/radiownet/message

Several Magecart campaigns turn out to be the work of one gang. The unfortunate persistence of DDoS-for-hire services. Ransomware’s growing sophistication as a class of criminal enterprise. Andrea Little Limbago from Interos on supply chain attacks & risks. Our guest is Mark Testoni from SAP's NS2 on how Covid-19 reshaped classified work. And hey kids: the BeagleBoyz are on a crime spree. For links to all of today's stories check out our CyberWire daily news brief: https://www.thecyberwire.com/newsletters/daily-briefing/9/167

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.08.11.245415v1?rss=1 Authors: Wang, W., Lin, X.-D., Zhang, H.-L., Wang, M.-R., Guan, X.-Q., Holmes, E. C., Zhang, Y.-Z. Abstract: To better understand the genetic diversity, host association and evolution of coronaviruses (CoVs) in China we analyzed a total of 696 rodents encompassing 16 different species sampled from Zhejiang and Yunnan provinces. Based on the reverse transcriptase PCR-based CoV screening CoVs of fecal samples and subsequent sequence analysis of the RdRp gene, we identified CoVs in diverse rodent species, comprising Apodemus agrarius, Apodemus latronum, Bandicota indica, Eothenomys miletus, E. eleusis, Rattus andamanesis, Rattus norvegicus, and R. tanezumi. Apodemus chevrieri was a particularly rich host, harboring 25 rodent CoVs. Genetic and phylogenetic analysis revealed the presence of three groups of CoVs carried by a range of rodents that were closely related to the Lucheng Rn rat coronavirus (LRNV), China Rattus coronavirus HKU24 (ChRCoV_HKU24) and Longquan Rl rat coronavirus (LRLV) identified previously. One newly identified A. chevrieri-associated virus closely related to LRNV lacked an NS2 gene. This virus had a similar genetic organization to AcCoV-JC34, recently discovered in the same rodent species in Yunnan, suggesting that it represents a new viral subtype. Notably, additional variants of LRNV were identified that contained putative nonstructural NS2b genes located downstream of the NS2 gene that were likely derived from the host genome. Recombination events were also identified in the ORF1a gene of Lijiang-71. In sum, these data reveal the substantial genetic diversity and genomic complexity of rodent-borne CoVs, and greatly extend our knowledge of these major wildlife virus reservoirs. Copy rights belong to original authors. Visit the link for more info

“Have a plan, but don't have it so rigorous that you miss opportunities. Don't let people talk you out of what your gut thinks is the right thing.” — Mark Testoni Today, Chad is joined by Mark Testoni CEO of SAP NS2. At the age of 20, Mark worked as a high school janitor but decided to turn the page and join the Air Force. He served in the military for 20 years, and since retiring , Mark has become an active spokesperson on veteran’s issues, discussing the importance of believing in yourself and building confidence.  “Confidence builds on itself. One of the things we have to do as leaders is to create situations for the people around us, whether they are family members, employees, colleagues at work, to have the opportunity to succeed and in some cases fail and overcome those tactical failures.” In 2013, Mark was the driving force behind the creation of NS2 Serves, an organization that provides technology training and employment assistance for veterans. He has helped 237 veterans graduate and be placed in high-tech careers, with another 100 projected to complete the program in 2019. His primary focus is on management, sales, consulting, product support, cloud-delivered applications and infrastructure, and go-to-market strategy.  On this episode of Mission Daily, Chad and Mark discuss the importance of leaders having empathy, how to mitigate your weaknesses by surrounding yourself with the right people, and a few key takeaways on how NS2 has grown rapidly.   — Mission Daily and all of our podcasts are created with love by our team at Mission.org. We own and operate a network of podcasts, and brand story studio designed to accelerate learning. Our clients include companies like Salesforce, Twilio, and Katerra who work with us because we produce results. To learn more and get our case studies, check out Mission.org/Studios. If you’re tired of media and news that promotes fear, uncertainty, and doubt and want an antidote, you’ll want to subscribe to our daily newsletter at Mission.org. When you do, you’ll receive a mission-driven newsletter every morning that will help you start your day off right!

This week on Promoter 101 The Podcast It's the 100th episode All-Star Spectacular Hosted By: Emporium’s Dan Steinberg and Works Entertainments’ Luke Pierce....joining Steiny and Luke to celebrate this massive mile stone are very special guests: Goldenvoice’s Elliott Lefko, ICM Partners’ Rick Farrell, FPC Live’s Scott Leslie, Vector’s Ross Schillings, Amplify / Billboards’ Dave Brooks, Live Nation’s Joey Scoleri, Lyte’s Ant Taylor, The Supermensch Shep Gordon, AGI’s Nick Storch, DZP’s Danny Zelisko, ICM Partners’ Andrea Johnson, APA’s Andy Somers, Nederlander Concerts’ Jamie Loeb, MGM Resorts’ Sid Greenfeig, Entourage Talent’s Wayne Forte, Live Nation’s Lesley Olenik, APA’s Steve Martin, Redlight’s Stuart Ross, Ns2’s Darin Lashinsky, Rocks Off’s Jake Szufnarowski, Atlantic Records’ Harlan Frey, Icon Tom Ross, The Brooklyn Bowl’s Peter Shapiro, AEG’s Max Adler, APA’s Craig Newman, Live Nation’s Jason Miller, Vector’s Brian Penix, IMP’s Seth Hurwitz, and Ticketfly’s Andrew Dreskin. Special Appearances by: AEG’s Toby Leighton Pope, Paradigm’s Jason Kupperman, Live Nation’s MaryClare Bourjaily, UTA’s Lance Roberts, Emporium Presents’ Jason Zink, Senbla’s Ollie Rosenblatt, CAA’s Brian Hill, New Fortier’s Paul Lohr, Paradigm’s Brian Swanson, AC’s Ted Heinig, Ticketmaster’s Jared Smith, and WME’s Jay Williams Direct Link: Spotify: https://is.gd/T5SPEC‬ ← JUST ADDED Email: steiny@promoter101.net Tweet the Guys: https://twitter.com/Promoters101 Tweet Dan: https://twitter.com/TheJew Tweet Luke: https://twitter.com/wlukepierce Follow us on iHeartRadio: https://www.iheart.com/podcast/promoter101-29260148/ Follow us on Instagram: https://www.instagram.com/steinypromoter101/ Facebook: https://www.facebook.com/promoter101 Soundcloud: https://soundcloud.com/promoter101 Website: http://www.promoter101.net/ itunes: https://itunes.apple.com/us/podcast/promoter101/id1163910658?mt=2 Google Music: https://is.gd/onEmSt Stitcher: http://www.stitcher.com/podcast/promoter101?refid=stpr Tumbler: http://promoter101.tumblr.com/ Spreaker: https://www.spreaker.com/user/promoter101 YouTube: https://www.youtube.com/promoter101 Edited by Connor Merritt - Connor@EmporiumPresents.com

This week on Promoter 101 The Podcast It's the 100th episode All-Star Spectacular Hosted By: Emporium’s Dan Steinberg and Works Entertainments’ Luke Pierce....joining Steiny and Luke to celebrate this massive mile stone are very special guests: Goldenvoice’s Elliott Lefko, ICM Partners’ Rick Farrell, FPC Live’s Scott Leslie, Vector’s Ross Schillings, Amplify / Billboards’ Dave Brooks, Live Nation’s Joey Scoleri, Lyte’s Ant Taylor, The Supermensch Shep Gordon, AGI’s Nick Storch, DZP’s Danny Zelisko, ICM Partners’ Andrea Johnson, APA’s Andy Somers, Nederlander Concerts’ Jamie Loeb, MGM Resorts’ Sid Greenfeig, Entourage Talent’s Wayne Forte, Live Nation’s Lesley Olenik, APA’s Steve Martin, Redlight’s Stuart Ross, Ns2’s Darin Lashinsky, Rocks Off’s Jake Szufnarowski, Atlantic Records’ Harlan Frey, Icon Tom Ross, The Brooklyn Bowl’s Peter Shapiro, AEG’s Max Adler, APA’s Craig Newman, Live Nation’s Jason Miller, Vector’s Brian Penix, IMP’s Seth Hurwitz, and Ticketfly’s Andrew Dreskin.Special Appearances by: AEG’s Toby Leighton Pope, Paradigm’s Jason Kupperman, Live Nation’s MaryClare Bourjaily, UTA’s Lance Roberts, Emporium Presents’ Jason Zink, Senbla’s Ollie Rosenblatt, CAA’s Brian Hill, New Fortier’s Paul Lohr, Paradigm’s Brian Swanson, AC’s Ted Heinig, Ticketmaster’s Jared Smith, and WME’s Jay WilliamsDirect Link:Spotify: https://is.gd/T5SPEC‬ ← JUST ADDEDEmail: steiny@promoter101.netTweet the Guys: https://twitter.com/Promoters101Tweet Dan: https://twitter.com/TheJewTweet Luke: https://twitter.com/wlukepierceFollow us on iHeartRadio: https://www.iheart.com/podcast/promoter101-29260148/Follow us on Instagram: https://www.instagram.com/steinypromoter101/Facebook: https://www.facebook.com/promoter101Soundcloud: https://soundcloud.com/promoter101Website: http://www.promoter101.net/itunes: https://itunes.apple.com/us/podcast/promoter101/id1163910658?mt=2Google Music: https://is.gd/onEmStStitcher: http://www.stitcher.com/podcast/promoter101?refid=stprTumbler: http://promoter101.tumblr.com/Spreaker: https://www.spreaker.com/user/promoter101YouTube: https://www.youtube.com/promoter101Edited by Connor Merritt - Connor@EmporiumPresents.com

On episode #007 of the Digital Pratik Show, we are gonna change the DNS and point our domain & hosting space at the same location which is NS1.BLUEHOST.COM & NS2.BLUEHOST.COMGo ahead and change it for your domain & Bluehost if you have recently purchased them!Also, by the way, you can now Enrol in Free "Digital Marketing Automation Course" now whose market value is $2997 but it will be free for you forever.Join Digital Pratik University today and become a lifetime member for free at: www.digitalpratikuniversity.com Follow me on Instagram: www.instagram.com/digitalpratik for 3 new video posts & 20-30 stories on daily basis.--- Send in a voice message: https://anchor.fm/digitalpratik/message

This week on Promoter 101 Recorded Live from The Western Arts Alliance Conference in Seattle, Washington, featuring a Industry panel with ICM Partners' Andrea Johnson, The Triple Door’s Scott Giampino, and ABI management / Ns2’s Brian Penix and Steiny and Luke bring you the News of the Week. Email: steiny@promoter101.net Tweet the Guys: https://twitter.com/Promoters101 Tweet Dan: https://twitter.com/TheJew Tweet Luke: https://twitter.com/wlukepierce Follow us on Instagram: https://www.instagram.com/steinypromoter101/ Facebook: https://www.facebook.com/promoter101 Soundcloud: https://soundcloud.com/promoter101 Website: http://www.promoter101.net/ itunes: https://itunes.apple.com/us/podcast/promoter101/id1163910658?mt=2 Google Music: https://is.gd/onEmSt Stitcher: http://www.stitcher.com/podcast/promoter101?refid=stpr Tumbler: http://promoter101.tumblr.com/ Spreaker: https://www.spreaker.com/user/promoter101 YouTube: https://www.youtube.com/promoter101

This week on Promoter 101 Recorded Live from The Western Arts Allience Conference in Seattle, Washington, featuring a Industry panel with ICM Partners' Andrea Johnson, The Triple Door’s Scott Giampino, and ABI management / Ns2’s Brian Penix and Steiny and Luke bring you the News of the Week. Email: steiny@promoter101.netTweet the Guys: https://twitter.com/Promoters101Tweet Dan: https://twitter.com/TheJewTweet Luke: https://twitter.com/wlukepierceFollow us on Instagram: https://www.instagram.com/steinypromoter101/Facebook: https://www.facebook.com/promoter101Soundcloud: https://soundcloud.com/promoter101Website: http://www.promoter101.net/itunes: https://itunes.apple.com/us/podcast/promoter101/id1163910658?mt=2Google Music: https://is.gd/onEmStStitcher: http://www.stitcher.com/podcast/promoter101?refid=stprTumbler: http://promoter101.tumblr.com/Spreaker: https://www.spreaker.com/user/promoter101YouTube: https://www.youtube.com/promoter101

This week on Promoter101 Dan caught up with ABI Management and NS2’s Brian Penix backstage in Seattle at the Moore Theatre during Tommy Emmanuel’s concert. Brian is day to day manager for Tommy Emmanuel, SIMO, and Andy McKee. Additionally, we are joined by HUB International’s top event insurance agent, Peter Tempkins with a client list that includes AC/DC and Van's Warped Tour. Dan and Luke sat down with Peter during Aspen Live Conference this past December. Plus Steiny and Luke break down the news of the week!

This week on Promoter 101 Features ABI Management and NS2’s Brian Penix, day to day manager for Tommy Emmanuel, SIMO, and Andy McKee. Plus HUB International’s top event insurance agent, Peter Tempkins handling the likes of AC/DC and Van's Warped Tour. Dan and Luke sat down with Peter during Aspen Live Conference this past December. Plus Steiny and Luke break down the news of the week!

I get the chance sit down and talk with Alex Hayton from Faultline Games about their game NS2: Combat, video game modding, modding vs a formal education, and more. So let us get suited up for combat and listen! E-mail: matthew@greyareapodcast.com Twitter: @darkone778 Web: www.soundstagepodcast.com Facebook: https://www.facebook.com/darkone778

I get the chance sit down and talk with Alex Hayton from Faultline Games about their game NS2: Combat, video game modding, modding vs a formal education, and more. So let us get suited up for combat and listen! You can follow all my random thoughts on things on Twitter @darkone778 and on Facebook www.facebook.com/darkone778 E-mail: jeneseegrey@yahoo.com Twitter: @darkone778 Web: https://greyareapodcast.com Facebook: https://www.facebook.com/darkone778

Hosts: Vincent Racaniello, Rich Condit, Alan Dove, and Kathy Spindler Vincent, Rich, Alan, and Kathy discuss regulation of influenza virus replication by splicing, and the bacteriophage T7 random walk. Links for this episode: Influenza splicing regulates infection (Cell Reports) Reporting on flu splicing from NPR, BBC, NBC Splicing of influenza RNA 8 (jpg) Bacteriophage T7 remodeling during infection (Science) Cryo-ET of intact cells (Trends Cell Biol) T7: The Movie (YouTube) Cry0-EM vs Cryo-ET (Wikipedia) Virus caught in the act (e! Science News) Letters read on TWiV 220 Weekly Science Picks Kathy - Journal of Virology Image GalleryRich - Phage T7 Genetics and Physiology and slab gelsAlan - PeerJ (press release)Vincent -  Virologia en Español Listener Pick of the Week Dave - Thingiverse pathogens and proteins  Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Respiratory syncytial virus (RSV) is recognised as the most frequent cause of severe lung infections in infants and cattle worldwide. Currently, no effective treatments are available and the development of a successful vaccine has been hampered by the fact that natural infection does not provide complete and durable protection. RSV nonstructural proteins, NS1 and NS2, are strong inhibitors of IFN α/β-production by specifically preventing interferon regulatory factor (IRF)-3 phosphorylation. However, the exact mechanisms leading to NS protein-mediated inhibition of IRF3 remain to be unravelled. One of the objectives of this study was to identify amino acid domains in the human respiratory syncytial virus (HRSV) nonstructural proteins (NS) responsible for their ability to ablate the IFN-β signalling pathway. Furthermore, I wanted to find out at which level of this signalling pathway the NS proteins exert their suppressive activity and which are their major cellular targets. HRSV strains A2 and Long differ in their ability to block interferon type I synthesis. Sequence analysis of their NS proteins revealed the presence of an amino acid residue in the NS2 protein with a potential role for RSV IFN-inhibitory functions. Two recombinant bovine respiratory syncytial (BRSV) viruses harbouring HRSV NS1 and NS2 genes were generated and tested in their ability to restrict IFN-β synthesis. These recombinant viruses differed only in the identity of the residue at position 26 of the HRSV NS2 protein: rBRSVh1/2 has a Threonine as in the Long strain, while in rBRS h1/2*T26I this amino acid was mutated into an Isoleucin similarly to A2 virus. Sets of in vitro tests revealed that IFN-β induction was impaired by rBRSVh1/2*T26I when compared to rBRSV h1/2. Analysis of the transcriptional factors (AP-1, NF-kB and IRF3) involved in the activation of IFN-β synthesis provided evidence that the inhibitory ability of rBRSVh1/2*T26I was correlated to a selective block of IRF3. The mutation (T26I) in the NS2 protein did neither effect the NF-kB activation pathway nor perturbed the IFN-resistance characteristics of the chimeric viruses. IRF3 is activated upon phosphorylation mediated by IKK-related kinases (TBK1 and IKK-ε). TBK1 was therefore cloned from a human lung cDNA library and its biological activities regarding the induction of IFN-β were compared in mock-infected and infected cells. rBRSVh1/2*T26I and HRSV A2 precluded virus-induced IRF3 activation by interfering with TBK1 functions. No direct interaction between TBK1 and NS2 protein was demonstrated indicating that the kinase TBK1 may not be the sole target involved in RSV mechanisms of evasion of the innate immune response. Recombinant IFN-inducible rabies viruses expressing HRSV Long-derived (rGFP-Ph2/1) or HRSV A2-like (rGFP-Ph2*T26I/1) NS proteins were also generated. The HRSV NS2 protein expressing an Isoleucin (NS2*T26I) at position 26 was not able to suppress IFN-β induction and to rescue the growth of the recombinant eGFP-Ph2*T26I/1 in interferon-competent cells. A low expression of the mutated NS2*T26I protein was probably the reason of this failure. In summary, these results show that the HRSV NS2 protein possesses an intrinsic IFN-β inhibitory activity, which is achieved throughout a selective inhibition of the IRF3 activation pathway. The block appears to be exerted at the level of IRF3-kinase TBK1. Interferonantagonist functions of the HRSV NS2 protein are linked to a particular amino acid motif in the N-terminus of the protein. Identification of this amino acid domain and of TBK1 as the cellular target provide a better insight of how the HRSV NS2 protein prevents the establishment of the antiviral innate immune response and therefore it might contribute to the development of an effective vaccine.

HRSV ist eine häufige und weltweit verbreitete Ursache von Infektionen des Respirationstraktes. Es führt zu einer entzündlichen Erkrankung der respiratorischen Schleimhäute mit Mukosaödem, Hypersekretion und Bronchospasmus. Die Übertragung des viralen Erregers erfolgt durch Tröpfcheninfektion oder Kontakt mit kontaminierten Gegenständen. HRSV-Infektionen zeigen die höchste Inzidenz bei Säuglingen, vor allem in den ersten zwei bis sechs Lebensmonaten. Bei 25% bis 40% dieser Säuglinge nimmt die Erkrankung einen schweren Verlauf mit Befall des unteren Respirationstraktes in Form einer HRSV-Bronchiolitis oder -Pneumonie. Bei 0,5% bis 2,0% ist eine stationäre Behandlung im Krankenhaus erforderlich. Die Inzidenz nimmt wegen des zunehmend effektiveren Immunsystems mit dem Alter ab. Erwachsene und ältere Kinder zeigen meist keine Symptome bzw. Symptome einer leichten Erkältung. Reinfektionen im Laufe des Lebens sind häufig. Eine effektive kausale Therapie bei HRSV-Infektionen steht derzeit nicht zur Verfügung. Bei Patienten mit leichtem Krankheitsverlauf ist keine spezielle Behandlung erforderlich, therapiert wird symptomatisch. Aktuell ist keine spezifische Prävention in Form einer aktiven Impfung oder als effektive antivirale Therapie etabliert. Angesichts der hohen Inzidenz von HRSV-Infektionen und -Reinfektionen sowie der enormen gesundheitlichen und wirtschaftlichen Auswirkungen ist ein effektiver Impfstoff gegen HRSV als Forschungsziel vorrangig. Das Genom von HRSV, das zur Ordnung der Mononegavirales gehört, besteht aus einem negativ-orientierten RNA-Einzelstrang mit einer Länge von 15 222 Nukleotiden (beim A2-Stamm) und kodiert für zehn subgenomische mRNAs in der Reihenfolge 3’-leader, NS1, NS2, N, P, M, SH, G, F, M2(1+2), L, trailer-5’, die zur Expression von elf viralen Proteinen führen: fünf RNP-assoziierte Proteine, das sind das Nukleoprotein N, das Phosphoprotein P, die große katalytische Untereinheit L der RNA-Polymerase und der Transkriptionselongationsfaktor M2-1 sowie das nicht essentielle M2-2-Protein; vier Hüllproteine, dazu zählen das nicht-glykosylierte Matrixprotein M und drei Oberflächenproteine, im Einzelnen das Fusionsprotein F, das Anheftungsprotein G und das kleine hydrophobe Protein SH; zwei Nicht-Strukturproteine NS1 und NS2. NS1 und NS2 zeichnen die Pneumoviren vor allen anderen Viren der Ordnung der Mononegavirales aus. Beide NS-Proteine sind im Virion nur in Spuren nachweisbar, während sie in infizierten Zellen akkumulieren. Die beiden für die Proteine NS1 und NS2 kodierenden, nichtüberlappenden Gene liegen am 3‘-Ende des Genoms direkt im Anschluss an die leader-Region. NS1 und NS2 stimmen in den vier carboxyterminalen Aminosäuren überein, ansonsten weisen sie keine Sequenzähnlichkeiten auf. Das NS1-Gen hat eine Länge von 552 nt und kodiert für ein leicht saures Protein von 139 AS und 15,7 kD. Das NS2-Gen ist 503 nt lang und kodiert für ein basisches Protein von 124 AS und 14,7 kD. Die für die Ordnung der Mononegavirales charakteristische progressive Attenuation der Transkription sowie die Genlokalisation von NS1 und NS2 am 3‘-Ende lassen auf die höchste Transkriptionsrate für NS1- und NS2-mRNA unter den zehn HSRV-mRNA schließen, was auf eine bedeutende Rolle der NS1- und NS2-Proteine in infizierten Zellen hindeutet. NS1 und NS2 antagonisieren im Zusammenwirken die durch alpha-IFN und beta-IFN induzierte antivirale Antwort des Wirtsorganismus. Hierfür ist eine Koexpression beider NS-Proteine unbedingt erforderlich, ein NS-Protein allein zeigt keine derartige Aktivität. Der Mechanismus, mit dem HRSV die IFN-Antwort des Wirtsorganismus umgeht, ist unklar. In dieser Arbeit wurde die Funktion der NS-Proteine von klinischen HRSV-Isolaten aus fünf bis fünfzehn Monate alten Kindern untersucht. Durch die Anzucht der klinischen HRSV-Isolate in HEp-2-Zellkultur unter identischen Bedingungen wurden zunächst patientenabhängige Faktoren ausgeschaltet und damit die Grundlage für die Vergleichbarkeit der Wachstumseigenschaften der Isolate geschaffen. In den daraufhin erstellten Wachstumskurven konnten deutlich voneinander abweichende Wachstumverhalten der Isolate aufgezeigt werden. Der Befund, dass 3/4 der Bronchiolitis hervorrufenden HRS-Viren hohe infektiöse Titer (>106 infektiöse Viruspartikel/ ml an Tag 3) erreichten, während dies nur bei 1/3 der Bronchitis verursachenden Viren zu beobachten war, könnte auf eine Korrelation zwischen Wachstum in vitro und Pathogenität in vivo hindeuten. Um dies zu belegen, müsste eine größere Zahl von klinischen Isolaten analysiert werden. Die beiden Nicht-Strukturproteine versetzen HRSV in die Lage, die antivirale IFN-Antwort der Wirtszelle zu umgehen. Durch Behandlung von Virus-infizierten Zellkulturen mit IFN ließ sich nachweisen, dass alle klinischen HRSV-Isolate die Eigenschaft der IFN-Resistenz gleichermaßen besitzen und erst durch unphysiologisch hohe IFN Dosen eine wesentliche Inhibierung der Virusreplikation erreicht werden kann. Die in gleicher Weise ausgeprägte α-IFN-Resistenz bei den in Virulenz und Wachstumsgeschwindigkeit unterschiedlichen Viren deutete bereits darauf hin, dass diese Resistenz essentiell für alle klinischen RSV-Isolate ist, und dass zusätzliche Faktoren für das Maß der Aggressivität der Erreger verantwortlich sind. Mittels Nukleotid- und Aminosäuresequenzanalysen von NS1 und NS2 konnte dies weitgehend bestätigt werden. Anhand von RNA aus den HRSV-Isolaten wurde mit Hilfe des Enzyms Reverse Transkriptase cDNA von NS1 und NS2 synthetisiert, die nach dem Prinzip der PCR in vitro amplifiziert wurde. In anschließenden Klonierungsarbeiten wurden aus dem Vektor pBluescript II SK (–) und NS1-DNA bzw. NS1+NS2-DNA als Insert Plasmide konstruiert, in denen die Gensequenzen von NS1 und NS2 ermittelt und rechnergestützt in die entsprechenden Aminosäuresequenzen translatiert wurden. Die Analyse der NS-Sequenzen zeigte eine überraschend hohe Konservierung. Die Isolate waren einschließlich des Long-Stamms diesbezüglich untereinander sehr ähnlich. Diese Beobachtung stimmt mit der IFN-Resistenz überein und zeigt die Bedeutung der NS-Proteine. Die Ergebnisse dieser Arbeit deuten darauf hin, dass Abweichungen in den Sequenzen der übrigen Gene sowie patientenbezogene Faktoren wie Abwehrlage und anatomische Beschaffenheit des Respirationstraktes als Grund für die Unterschiede im Schweregrad der HRSV-Infektion eine Rolle spielen. Angesichts der stabilen Koexpression beider Nicht-Strukturproteine und des dadurch bedingten effektiven IFN-Escape sichern die Gene NS1 und NS2 die Überlebensfähigkeit von HRSV in vivo und stellen ebenso geeignete wie interessante Angriffspunkte in der Entwicklung eines attenuierten Lebendimpfstoffs dar.

Among the Paramyxoviridae, only members of the subfamily Pneumovirinae like Respiratory Syncytial Virus (RSV) encode two nonstructural proteins, NS1 and NS2. These two proteins cooperatively mediate type I interferon resistance and prevent induction of interferon in infected cells. Interactions of NS1 and NS2 proteins in every combination were shown by using the yeast-two-hybrid system. Therfore, NS1 and NS2 are able to form homo- and hetero(oligo)mers in infected cells. Although RSV replicates exclusively in the cytoplasm, NS-Proteins are localized in the cytoplasm as well as in the nucleus. Expression of an enlarged NS1 fusion protein, EGFP-NS1-BRSV N, resulted in the same nuclear and cytosolic localisation indicating that nuclear localisation is not due to diffusion but rather to an active transport. Thus, NS-Proteins should have particular functions in the nucleus of infected cells. Furthermore, yeast-two-hybrid screening of a lung cDNA expression library using NS1 of bovine RSV (BRSV) as a bait, identified cDNA clones encoding several nuclear proteins and one cytosolic protein. BRSV NS2 protein and NS-Proteins from other pneumoviruses (HRSV, PVM) were also able to interact with the identified cellular proteins in yeast. The isolated cDNAs encode the nuclear proteins CDK4BP (p34SEI-1 or TRIP-Br1), RanBP16, MM-1, DEAD Box Helicase p68 and the cytosolic β-COPI. Specific interactions were determined by mutational analysis of BRSV NS1 in yeast. Co-immunoprecipitation from lysates of eukaryotic cells confirmed the interaction of both BRSV NS-Proteins with the cellular proteins. The interaction of MM-1 and p68 with both NS-Proteins was also shown in GST pull down assay in vitro. Engineered BRSV encoding a truncated p68 showed accelerated replication in MDBK and Vero cells, whereas growth of NS1/NS2 deletion mutants expressing the truncated p68 was unaffected. This indicates that the presence of NS-Proteins is a prerequisite for the acceleration of BRSV growth by truncated p68. Furthermore, replication of BRSV was attenuated on HeLa cells in which expression of p68 was knocked down by specific siRNA, whereas replication of the unrelated Rabies virus was not. Thus, p68 is a nuclear target protein for the NS-Proteins and supports BRSV replication in vitro. Growth and division of host cells is necessary for optimal BRSV replication and like p68, most of the identified nuclear protein interactors are related to regulation of the cell cycle and cell division, respectively. Therefore, NS-Proteins appear to influence the cell cycle for optimal replication of BRSV by targeting such proteins. Hence, with the yeast-two-hybrid system, the first cellular interaction partners were identified indicating new functions of NS-Proteins in the viral replication cycle.

Bovine respiratory syncytial virus (BRSV), family Paramyxoviridae, subfamily Pneumovirinae, is a major etiological agent of respiratory tract disease in calves. A peculiarity of pneumoviruses is the presence of two unique nonstructural protein genes, NS1 and NS2. We show that both BRSV NS proteins are necessary and sufficient to mediate IFN resistance. This function can also be transferred to another, unrelated virus, Rabies virus. The mechanism of IFN resistance is conserved among the Pneumovirinae since the NS proteins of human RSV (HRSV) and of Pneumoniavirus of Mice (PVM) are also able to mediate IFN resistance in a similar manner. Furthermore, both BRSV NS proteins are able to block the induction of IFN by inhibiting the activation of interferon regulatory factor 3 (IRF-3). As a result, BRSV is able to block the establishment of a cellular antiviral state. The characterization of interactions between virus (NS proteins) and the host cell (IFN system) will have important implications in the development of HRSV/BRSV vaccines