Podcasts about alzheimer's disease

Discover the game-changing world of nanobubble oxygen therapy with Jason Applewhite from Bimini Hydrotherapy! In this episode of Beautifully Broken, host Freddie Kimmel chats with Jason about how Bimini's devices deliver oxygen through your skin via tiny nanobubbles—2,500x smaller than a skin pore—while you soak in a bath or foot tub.Say goodbye to claustrophobic hyperbaric chambers! Learn why nanobubbles could be a superior alternative for athlete recovery, chronic illness (like Lyme, mold, neuropathy, and Alzheimer's), inflammation reduction, better sleep, and even skin health. Jason shares pro athlete stories (e.g., NFL stars like Derek Henry), comparisons to HBOT and EWOT, and how Bimini stacks up against competitors like Cocoon.HIGHLIGHTS:[00:00] What is nano bubble oxygen therapy and why it matters[02:59] Why Amazon's review system doesn't guarantee supplement quality[04:01] Freddie's experience with Lyme and the promise of localized oxygen delivery[08:28] How oxygen therapy upregulates lymphatic drainage[10:31] How technology shifts state—but lasting change needs your participation[18:33] Comparing bath-based nano oxygen vs. hyperbarics and EWOT[24:00] Making oxygen therapy more accessible with footbaths[27:08] Bath #1: The surprising systemic effects Freddie noticed[32:39] When to expect deeper benefits—timeline of results[41:52] Breath-holding, eye immersion, and getting creative with therapy[44:54] The power of footbaths for seniors or limited mobility users[50:39] Freddie's dream wellness stack and why oxygen must be in the mix[53:48] Competitor shoutout: Cocoon's cancer focus and industry evolutionLinks & Resources:Bimini Hydrotherapy ($500 off with code BEAUTIFULLYBROKEN) - https://biminihydrotherapy.com/Work with Me-Join the new Biological Blueprinthttps://www.beautifullybroken.world/biological-blueprintOptimize your Terrain:BEAM Minerals: http://beamminerals.com/beautifullybrokenUse Code: BEAUTIFULLYBROKEN for discountSilver Biotics: https://silverbiotics.com/Use Code: BEAUTIFULLYBROKEN for discount CONNECT WITH FREDDIEWork with Me: https://www.beautifullybroken.world/biological-blueprintWebsite and Store: (http://www.beautifullybroken.world) Instagram: (https://www.instagram.com/beautifullybroken.world/) YouTube: (https://www.youtube.com/@BeautifullyBrokenWorld)

Literature Review 1) An exciting phase three trial with the CETP inhibitor Obicetrapib has shown serious promise for ASCVD and Alzheimer's Disease (AD). "In BROADWAY, a pre-specified AD sub-study was designed to assess plasma AD biomarkers in patients enrolled in the BROADWAY trial and evaluated the effects of longer duration of therapy (12 months) with a prespecified population of ApoE3/4 or 4/4 carriers. The sub-study included 1727 patients, including 367 ApoE4 carriers. The primary outcome measure was p-tau217 absolute and percent change over 12 months. Additional outcome measures included neurofilament light chain (“NFL”), glial fibrillary acidic protein (“GFAP”), p-tau181, and Aβ42/40 ratio absolute and percent change over 12 months. NewAmsterdam observed statistically significant lower absolute changes in p-tau217 compared to placebo over 12 months in both the full ITT population (p

Most people assume creatine is only for bodybuilders, but new research is challenging that belief. In this episode, Chalene dives into the surprising, science-backed benefits of creatine for women, particularly those in midlife. From brain health and bone density to hormonal support and cognitive function, this supplement might be one of the most underrated tools for aging powerfully. She also busts common myths like weight gain and bloating, and explains why some experts are calling it “the magnesium of 2025.” If you're curious about how to take it, which brands are trustworthy, and how to avoid getting scammed, this episode lays it all out. Watch this episode on YouTube this Sunday!!  https://www.youtube.com/@chalenejohnson/videos  

The August 2025 recall spotlights four previously released episodes on topics related to dementia diagnosis. The episode begins with Dr. Amy Brodtmann discussing the complexities of diagnosing frontotemporal dementia in clinical practice. Next, Dr. Joseph Therriault delves into the use of plasma biomarkers in diagnosing Alzheimer disease. In the third episode, Dr. Trey Bateman discusses the growing significance of blood-based biomarkers in Alzheimer disease. The episode concludes with Dr. Gregg Day discussing the clinical implications of using plasma biomarkers in real-world patient care. Podcast links:  Frontotemporal Dementia Differential Diagnosis in Clinical Practice Diagnosis of Alzheimer Disease Using Plasma Biomarkers Understanding Blood-Based Biomarkers in Alzheimer Disease Diagnostic Performance of Plasma Biomarkers in the Outpatient Memory Clinic Article links:  Frontotemporal Dementia Differential Diagnosis in Clinical Practice Diagnosis of Alzheimer's Disease Using Plasma Biomarkers Adjusted to Clinical Probability Diagnostic Performance of Plasma p-tau217 and Aβ42/40 Biomarkers in the Outpatient Memory Clinic Disclosures can be found at Neurology.org. 

This is the last special solo episode for a while. Thankfully, Robert and Joe will be back next week to make nonsense about marketing and content news. But today's episode is something a little different. In 1937, Napoleon Hill wrote Think and Grow Rich. His ideas about belief, desire, and persistence changed lives—Joe's included. Joe's new book, Burn the Playbook, is his answer to what Think and Grow Rich would look like today. It's not just about financial wealth...it's about freedom. Mental freedom. Physical health. Time freedom. It's the book Joe wanted his kids to have…the book that they could share with their kids about living a life of purpose. This episode of This Old Marketing is about how to build a platform strong enough to carry the weight of your dreams. Six months ago, Joe was 20 pounds heavier. He felt foggy, sluggish, reactive. He was still productive, sure...but didn't feel sharp. He didn't feel like he was operating at his best. And he decided that wasn't okay anymore. Many of you know this, but Joe's family has a history of Alzheimer's as well. He always thought he was relegated to this fate and there was nothing he could do. Joe's since found there are many things he can do to build a better brain (if you will), so that he can live a better life and be around, in all forms, for his kids and their kids, in addition to living a life of freedom (which we'll discuss). So he made some changes. Not radical ones. Just simple, consistent ones. And Joe wants to share them with you—not as a health expert, but as a creator who realized that if your body and brain break down, your business doesn't stand a chance. Let's get into it.   ----- This week's links: Americans Check Phone 144 Times Per Day The Cost of Multitasking ----- This week's sponsor: You don't become the world's most valuable women's sports franchise by accident. Angel City Football Club did it with a little help from HubSpot. When they started, data was housed across multiple systems. HubSpot unified their website, email marketing, and fan experience in one platform. This allowed their small team of three to build an entire website in just three days. The results? Nearly 350 new sign-ups a week and 300% database growth in just two years. Visit https://www.hubspot.com/ to hear how HubSpot can help you grow better. ------- Liked this show? SUBSCRIBE to this podcast on Spotify, Apple, Google and more. Catch past episodes and show notes at ThisOldMarketing.com. Catch and subscribe to our NEW show on YouTube. NOTE: You can get captions there. Subscribe to Joe Pulizzi's Orangeletter and get two free downloads direct from Joe. Subscribe to Robert Rose's newsletter at Seventh Bear.

Intimate partner violence (1:40), top 20 research studies of 2024 for primary care physicians (5:20), treatments for carpal tunnel syndrome (11:20), benzgalantamine for Alzheimer disease (13:50), bright light therapy (17:50), assessment and management of patients at risk for suicide (20:10).

In this re-released solo episode from 2023, Dr. Mike Belkowski revisits one of the most pivotal topics in the world of mitochondrial health: methylene blue. As interest in this powerful compound continues to grow, Dr. Mike brings back an essential conversation outlining its top ten benefits — from brain function and mood to immune support to antiviral activity and beyond!   He also shares exciting updates about the future of the podcast, including a rebrand launching in August and a major expansion of the Mitochondrial Triad into the Mitochondrial Core Four. You'll also hear about BioLight's newest supplement, BioBlue Fountain of Youth, and how combining methylene blue with red light therapy can lead to powerful healing synergy.   Whether you're brand new to methylene blue or a longtime user, this episode will deepen your understanding of why this blue dye might just be the missing link in your health toolkit. If you care about energy, mood, memory, immunity — or just want to future-proof your brain — this episode is packed with insights you won't want to miss! - Key Quotes from Dr. Mike Belkowski: “Red light therapy and methylene blue on their own are powerful tools. But when you use them together, you're getting a synergistic benefit that may be unmatched in the world of mitochondrial health.”   “The more I read, the more I research, the more I realize: this compound that started as a dye might be one of the most important mitochondrial tools we have.”   “Methylene blue has been around since the 19th century. It's safe, it's effective, and the amount of research backing its antiviral, neuroprotective, and metabolic benefits is staggering.”   Key Points:   00:00 – Introduction: A Podcast Rebrand and New Direction   03:11 – Evolving the Mitochondrial Triad into the Core Four   05:17 – Why Methylene Blue Deserves a Second Look   07:15 – BioBlue: A New Mitochondrial-Enhancing Supplement   10:45 – NMN, Folic Acid, and Gold-Silver Nanoparticles Explained   11:07 – The History of Methylene Blue: From Textile Dye to Healing Tool   15:11 – Fish Tanks, Surgery, and the Safety of MB   17:57 – Malaria Cures and Forgotten Medicine   20:16 – BioBlue FOY: The Cadillac of Mitochondrial Supplements   21:38 – Methylene Blue + Red Light = Antiviral Powerhouse   22:29 – Cognitive Enhancement, Memory, and Focus Support   23:00 – Rapid Mood Shifts and Depression Relief   24:26 – Reversing Alzheimer's: A Look at the Research   29:25 – How MB Boosts Mitochondrial Energy at the Molecular Level   31:31 – Hormonal Benefits: More Energy, Less Estrogen, Higher Testosterone   32:00 – MB as an Antidote for Poisoning and Metabolic Toxins   36:29 – Methylene Blue's Powerful Antiviral Capabilities   44:12 – Alzheimer's Hallmarks Reversed with MB and Red Light Therapy   55:11 – Autism, Gut Health, and Restoring Mitochondrial Function   58:44 – The Nitric Oxide Link to Depression and Brain Fog   01:03:07 – Bipolar and Mood Stabilization Studies with MB   01:04:27 – Autism, Oxidative Stress, and Endotoxin Insights   01:13:33 – MB as a Rapid Pain Reliever for Surgery and Chronic Conditions BLUE SPECIAL THIS WEEK... SAVE 20% ON ALL BIOBLUE SUPPLEMENTS!!   Choose from our wide range of BioBlue products — four varieties of liquid BioBlue and four varieties of encapsulated BioBlue. Need help figuring out which BioBlue makes the most sense for you? Respond to this email!Discount code: BLUEPODCAST Expires Thursday, 8/7, midnight PST*Discount code is not valid with bundles or 2-, 4- or 10-packs. Must use "single" option and then increased to desired quantity.   Shop all BioBlue products by clicking here! - Dr. Mike's #1 recommendations:Water products: Water & WellnessGrounding products: Earthing.com EMF-mitigating products: Somavedic Blue light blocking glasses: Ra Optics  

Hey Heal Squad! We often talk about gut health, inflammation, and brain fog, but what if it all starts in your mouth? In Part 2 of our conversation with world-renowned dentist and oral wellness expert Dr. Jonathan Levine, they dive deep into how oral health isn't just about cavities and cleanings, but a direct reflection of your whole-body health. Dr. Levine explains how the oral microbiome impacts your immune system, digestion, cognitive health, and even your risk of chronic disease. You'll learn how mouth bacteria can travel through your body via the gut and bloodstream. And yes, your daily dental routine plays a much bigger role than you think. He also breaks down his “4-minute protocol” for optimal oral hygiene to protect your mouth (and your brain). Tune in and discover the power of preventative oral care, inside and out!  HEALERS & HEAL LINERS:  Mouth microbes = full-body mess: Poor oral hygiene can allow harmful bacteria to enter your bloodstream, disrupting gut health, triggering inflammation, and impacting your overall health. Daily habits matter: Dr. Levine explains how a 4-minute oral health protocol can dramatically improve energy, immunity, and long-term wellness. Your mouth talks to your brain: Emerging science shows that oral health is deeply connected to cognitive decline. Dr. Levine reveals how dental inflammation could be a hidden contributor to brain fog, Alzheimer's, and more. -- HEAL SQUAD SOCIALS IG: https://www.instagram.com/healsquad/ TikTok: https://www.tiktok.com/@healsquadxmaria HEAL SQUAD RESOURCES: Heal Squad Website:https://www.healsquad.com/ Heal Squad x Patreon: https://www.patreon.com/HealSquad/membership Maria Menounos Website: https://www.mariamenounos.com My Curated Macy's Page: Shop My Macy's Storefront Prenuvo: Prenuvo.com/MARIA for $300 off EMR-Tek Red Light: https://emr-tek.com/discount/Maria30 for 30% off Airbnb: https://www.airbnb.com/  Join In-Person Heal Retreat Waitlist! https://mariamenounos.myflodesk.com/heal-retreat-waitlist GUEST RESOURCES: Instagram: https://www.instagram.com/drjonlevine/?hl=en Website: https://www.drjonathanlevine.com/  Smile House: https://www.instagram.com/smilehousetribeca/  JBL: https://www.instagram.com/jblnewyorkcity/  If you're in NYC, Dr. Levine is offering one complimentary whitening treatment when you book a Mouth Mapping appointment at Smile House or JBL NYC. Just Mention Heal Squad or Maria's podcast when booking.  Not in the city? Dr. Levine has curated a comprehensive Home Care Guide just for you. Visit @SmileHouseTribeca on Instagram and DM "GUIDE" to receive your free guide! ABOUT MARIA MENOUNOS: Emmy Award-winning journalist, TV personality, actress, 2x NYT best-selling author, former pro-wrestler and brain tumor survivor, Maria Menounos' passion is to see others heal and to get better in all areas of life. ABOUT HEAL SQUAD x MARIA MENOUNOS: A daily digital talk-show that brings you the world's leading healers, experts, and celebrities to share groundbreaking secrets and tips to getting better in all areas of life. DISCLAIMER: This Podcast and all related content (published or distributed by or on behalf of Maria Menounos or http://Mariamenounos.com and http://healsquad.com) is for informational purposes only and may include information that is general in nature and that is not specific to you. Any information or opinions provided by guest experts or hosts featured within website or on Company's Podcast are their own; not those of Maria Menounos or the Company. Accordingly, Maria Menounos and the Company cannot be responsible for any results or consequences or actions you may take based on such information or opinions. This podcast is presented for exploratory purposes only. Published content is not intended to be used for preventing, diagnosing, or treating a specific illness. If you have, or suspect you may have, a health-care emergency, please contact a qualified health care professional for treatment.

Dementia is a syndrome associated with a decline of brain function that can affect memory, thought processes and behaviour. In some cases this can impact people's ability to shop, cook and eat a meal. The most common form of dementia is Alzheimer's Disease. In this programme Ruth Alexander meets people living with dementia and their families, to hear about the ways in which a diagnosis can impact mealtimes. Ruth meets Alan and Amy Lambert in Manchester, England. Alan was diagnosed with Alzheimer's Disease in 2024 and his daughter Amy lives with him. They share some of the techniques they've developed at home to support Alan. For Ruby Qureshi in Canada, cooking was a huge part of her life before being diagnosed with Alzheimer's in 2020. Ruth hears how her husband Pasha Qureshi has joined her in the kitchen in a supporting role. Jo Bonser in Nottingham, UK shares her experiences of supporting her mother who lived with vascular dementia and in 2016 stopped eating and drinking. Jo has gone on to set up a company, Dignified Dining that offers training in this area. And Aideen McGuinness is a registered dietitian working in the Memory Assessment and Support Service in Country Wexford Ireland, and co-author of a guide on dementia and nutrition. If you would like to get in touch with the show, please email: thefoodchain@bbc.co.uk Produced by Beatrice Pickup. (Image: Alan and Amy Lambert sat at the kitchen table with a bowl of soup and plate of toast. Credit: BBC)

Dr. Jacob Teitelbaum, integrative medicine physician, researcher, and best-selling author, details preventive measures and treatments for cognitive decline, including dementia and Alzheimer's disease. He covers a wide range of topics, including the impact of conventional medications, natural supplement alternatives, dietary interventions, the role of exercise, and the importance of addressing underlying health issues like thyroid problems and metabolic syndrome. Dr. Teitelbaum emphasizes practical and low-cost approaches, and he offers listeners detailed resources and guidance.

J Smiles has been a caregiver to her mom living with Alzheimer's and NPH for over 13 years—an unexpected journey that began after her father's sudden passing. Once a globe-trotting consultant who could barely keep a plant alive, J found herself overwhelmed and facing serious health issues just 18 months into caregiving. A wake-up call from her doctor led her to explore self-care through stand-up comedy. In this episode, J shares how comedy became her lifeline, helping her cope, advocate for caregivers, and bring joy to others walking a similar path. Show notes with product and resource links: https://bit.ly/HHCPod210 Receive the podcast in your email here: http://bit.ly/2G4qvBv Order a copy of Elizabeth's book Just for You: a Daily Self Care Journal: http://bit.ly/HHCjournal For podcast sponsorship opportunities contact Elizabeth: https://happyhealthycaregiver.com/contact-us/ The Happy Healthy Caregiver podcast is part of the Whole Care Network. Rate and Review the podcast: https://bit.ly/HHCPODREVIEW

This is a free preview of a paid episode. To hear more, visit visitationsessions.substack.comThe Chapmans are back in Illinois this week, so Emily can spend some time with her mom, whose Alzheimer's continues to worsen. There wasn't time before they left to record a new episode, but after we recorded our last episode, we did manage to record a quick bonus episode for our full subscribers. We're sharing that here today. The topic: Anxiety.A read…

Bree Groff thinks it's an emergency that half of us feel dread at work every week, and that we're trading five‑sevenths of our lives just to reach Friday. In this conversation with Ryan, the former NOBL CEO and current SYPartners advisor traces how losing her mom to cancer and caring for a dad with Alzheimer's jolted her from helping leaders execute their vision to stating her own. She introduces a few characters and themes from her latest book, Today Was Fun, including Bob the Alien, who decides Google Calendar secretly runs Earth. Bree's metric is simple: curl into bed most nights and honestly say, today was fun. If not, rewrite the rules—you made them up anyway.

Think menopause means saying goodbye to a good night's sleep? Think again.In this episode, I unpack the real reasons why your sleep is suffering—and what you can do to start sleeping deeply again. These aren't just tips. They're game-changing strategies for your midlife brain and body.What to Listen For:[00:03:00] Why menopausal insomnia is not all in your head—it's hormonal.[00:04:00] How declining melatonin, estrogen, and progesterone hijack your sleep cycle.[00:07:00] The "wired but tired" feeling and why cortisol is to blame.[00:09:00] Why generic sleep advice fails during menopause—and what actually helps.[00:10:00] The non-negotiable habits to reset your circadian rhythm.[00:11:00] Affordable (and high-tech) cooling solutions to reduce night sweats.[00:14:00] How to create a “wind down system” that soothes your nervous system.[00:15:00] The power of morning sunlight and foods that support sleep hormones.[00:18:00] Smart movement tips: when and what kind of exercise actually supports sleep.[00:20:00] The truth about hormone therapy (MHT) and how it changed my life.Menopausal sleep disruption doesn't mean your body is in decline—it's a biological response to massive hormonal changes. The good news? There are science-backed strategies that can bring relief. If you're ready to move from “wired and tired” to well-rested and refreshed, this episode is your first step.Subscribe & Review in iTunesIf you like what you hear, please subscribe to my podcast.  I encourage you to do that today as I don't want you to miss an episode.  Click here to subscribe on iTunes!Now if you're feeling extra loving, I would be really grateful if you left me a review over on iTunes, too. Those reviews help other people find my podcast and they're also fun for me to go in and read. Just click here to review, select “Ratings and Reviews” and “Write a Review” and let me know what your favorite part of the podcast is.RESOURCES: Register for the FREE Masterclass: 5 Keys to Protecting Your Brain Health Book a FREE Discovery Call with Amy Lang Order Amy's book Thoughts Are Habits Too: Master Your Triggers, Free Yourself From Diet Culture, and Rediscover Joyful Eating. Follow Amy on Instagram @habitwhisperer

In this episode, Lyell K. Jones Jr, MD, FAAN, speaks with Michael S. Okun, MD, FAAN, who served as the guest editor of the August 2025 Movement Disorders issue. They provide a preview of the issue, which publishes on August 1, 2025. Dr. Jones is the editor-in-chief of Continuum: Lifelong Learning in Neurology® and is a professor of neurology at Mayo Clinic in Rochester, Minnesota. Dr. Okun is the director at Norman Fixel Institute for Neurological Diseases and distinguished professor of neurology at University of Florida in Gainesville, Florida. Additional Resources Read the issue: continuum.aan.com Subscribe to Continuum®: shop.lww.com/Continuum Continuum® Aloud (verbatim audio-book style recordings of articles available only to Continuum® subscribers): continpub.com/Aloud More about the American Academy of Neurology: aan.com Social Media facebook.com/continuumcme @ContinuumAAN Host: @LyellJ Guest: @MichaelOkun Full episode transcript available here: Dr Jones: Our ability to move through the world is one of the essential functions of our nervous system. Gross movements like walking ranging down to fine movements with our eyes and our hands, our ability to create and coordinate movement is something many of us take for granted. So what do we do when those movements stop working as we intend? Today I have the opportunity to speak with one of the world's leading experts on movement disorders, Dr Michael Okun, about the latest issue of Continuum on Movement Disorders. Dr Jones: This is Dr Lyell Jones, Editor-in-Chief of Continuum. Thank you for listening to Continuum Audio. Be sure to visit the links in the episode notes for information about subscribing to the journal, listening to verbatim recordings of the articles, and exclusive access to interviews not featured on the podcast. Dr Jones: This is Dr Lyle Jones, Editor-in-Chief of Continuum: Lifelong Learning in Neurology. Today, I'm interviewing Dr Michael Okun, who is Continuum's guest editor for our latest issue on movement disorders. Dr Okun is the Adelaide Lackner Distinguished Professor of Neurology at the University of Florida in Gainesville, where he's also the director of the Norman Fixel Institute for Neurological Diseases. Dr Okun, welcome, and thank you for joining us today. Why don't you introduce yourselves to our listeners?  Dr Okun: It's great to be here today. And I'm a neurologist. Everybody who knows me knows I'm pretty simple. I believe the patient's the sun and we should always orbit around the person with disease, and so that's how I look at my practice. And I know we always participate in a lot of research, and I've got a research lab and all those things. But to me, it's always the patients and the families first. So, it'll be great to have that discussion today.  Dr Jones: Yeah, thank you for that, Dr Oaken. Obviously, movement disorders is a huge part of our field of neurology. There are many highly prevalent conditions that fit into this category that most of our listeners will be familiar with: idiopathic Parkinson's disease, essential tremor, tic disorders and so on. And having worked with trainees for a long time, it's one of the areas that I see a lot of trainees gravitate to movement disorders. And I think it's in part because of the prevalence; I think it's in part because of the diversity of the specialty with treatment options and DBS and Botox. But it's also the centrality of the neurologic exam, right? That's- the clinical examination of the patient is so fundamental. And we'll cover a lot of topics today with some questions that I have for you about biomarkers and new developments in the field. But is that your sense too, that people are drawn to just the old-fashioned, essential focus on the neurologic encounter and the neurologic exam? Dr Okun: I believe that is one of the draws to the field of movement. I think that you have neurologists from all over the world that are really interested and fascinated with what things look like. And when you see something that's a little bit, you know, off the normal road or off the normal beaten path… and we are always curious. And so, I got into movement disorders, I think, accidentally; I think even as a child, I was looking at people who had abnormal movements and tremors and I was very fascinated as to why those things happened and what's going on in the brain. And, you know, what are the symptoms and the signs. And then later on, even as my own career developed, that black bag was so great as a neurologist. I mean, it makes us so much more powerful than any of the other clinicians---at least in my biased opinion---out on the wards and out in the clinic. And, you know, knowing the signs and the symptoms, knowing how to do a neurological examination and really walking through the phenomenology, what people look like, you know, which is different than the geno- you know, the genotypes, what the genes are. What people look like is so much more important as clinicians. And so, I think that movement disorders is just the specialty for that, at least in my opinion. Dr Jones: And it helps bring it back to the patient. And that's something that I saw coming through the articles in this issue. And let's get right to it. You've had a chance to review all these articles on all these different topics across the entire field of movement disorders. As you look at that survey of the field, Dr Okun, what do you think is the most exciting recent development for patients with movement disorders?  Dr Okun: I think that when you look across all of the different specialties, what you're seeing is a shift. And the shift is that, you know, a lot of people used to talk in our generation about neurology being one of these “diagnose and adios” specialties. You make the diagnosis and there's nothing that you can do, you know, about these diseases. And boy, that has changed. I mean, we have really blown it out of the water. And when you look at the topics and what people are writing about now and the Continuum issue, and we compare that the last several Continuum issues on movement disorders, we just keep accumulating a knowledge base about what these things look like and how we can treat them. And when we start thinking about, you know, all of the emergence of the autoimmune disorders and identifying the right one and getting something that's quite treatable. Back in my day, and in your day, Lyle, we saw these things and we didn't know what they were. And now we have antibodies, now we can identify them, we can pin them down, and we can treat many of them and really change people's lives. And so, I'm really impressed at what I see in changes in identification of autoimmune disorders, of channelopathies and some of the more rare things, but I'm also impressed with just the fundamental principles of how we're teaching people to be better clinicians in diseases like Parkinson's, Huntington's, ataxia, and Tourette. And so, my enthusiasm for this issue of Continuum is both on, you know, the cutting edge of what we're seeing based on the identification on our exams, what we can do for these people, but also the emergence of how we're shifting and providing much better care across a continuum for folks with basal ganglia diseases. Dr Jones: Yeah, I appreciate that perspective, Dr Okun. One of the common themes that I saw in the issue was with these new developments, right, when you have new tools like new diagnostic biomarker tools, is the question of if and when and how to integrate those into daily clinical practice, right? So, we've had imaging biomarkers for a while, DAT scans, etc. For patients with idiopathic Parkinson disease, one of the things that I hear a lot of discussion and controversy about are the seed amplification assays as diagnostic biomarkers. What can you tell us about those? Are those ready for routine clinical use yet?  Dr Okun: I think the main bottom-line point for folks that are out there trying to practice neurology, either in general clinics or even in specialty clinics, is to know that there is this movement toward, can we biologically classify a disease? One of the things that has, you know, really accelerated that effort has been the development of these seed amplification assays, which---in short for people who are listening---are basically, we “shake and bake” these things. You know? We shake them for like 20 hours and we use these prionlike proteins, and we learn from diseases like prion disease how to kind of tag these things and then see, do they have degenerative properties? And in the case of Parkinson's disease, we're able to do this with synuclein. That is the idea of a seed amplification assay. We're able to use this to see, hey, is there synuclein present or not in this sample? And people are looking at things like cerebrospinal fluid, they're looking at things like blood and saliva, and they're finding it. The challenge here is that, remember- and one of the things that's great about this issue of Continuum is, remember, there are a whole bunch of different synucleinopathies. So, Dr Jones, it isn't just Parkinson's disease. So, you've got Parkinson's disease, you've got Lewy body, you know, and dementia with Lewy bodies. You've got, you know, multiple system atrophy is within that synucleinopathy, you know, group primary autonomic failure… so not just Parkinson's disease. And so, I think we have to tap the brakes as clinicians and just say, we are where we are. We are moving in that direction. And remember that a seed amplification assay gives you some information, but it doesn't give you all the information. It doesn't forgive you looking at a person over time, examining them in your clinic, seeing how they progress, seeing their response to dopamine- and by the way, several of these genes that are associated with Parkinson; and there's, you know, less than 20% of Parkinson is genetic, but several of these genes, in a solid third---and in some cases, in some series, even more---miss the synuclein assay, misses, you know, the presence of a disease like Parkinson's disease. And so, we have to be careful in how we interpret it. And I think we're more likely to see over time a gemish: we're going to smush together all this information. We're going to get better with MRIs. And so, we're actually doing much better with MRIs and AI-based intelligence. We've got DAT scans, we've got synuclein assays. But more than anything, everybody listening out there, you can still examine the person and examine them over time and see how they do over time and see how they do with dopamine. And that is still a really, really solid way to do this. The synuclein assays are probably going to be ready for prime time more in choosing and enriching clinical trials populations first. And you know, we're probably 5, 10 years behind where Alzheimer's is right now. So, we'll get there at some point, but it's not going to be a silver bullet. I think we're looking at these are going to be things that are going to be interpreted in the context for a clinician of our examination and in the context of where the field is and what you're trying to use the information for. Dr Jones: Thank you for that. And I think that's the general gestalt I got from the articles and what I hear from my colleagues. And I think we've seen this in other domains of neurology, right? We have the specificity and sensitivity issues with the biomarkers, but we also have the high prevalence of copathology, right? People can have multiple different neurodegenerative problems, and I think it gets back to that clinical context, like you said, following the patient longitudinally. That was a theme that came out in the idiopathic Parkinson disease article. And while we're on Parkinson disease, you know, the first description of that was what, more than two hundred years ago. And I think we're still thinking about the pathophysiology of that disorder. We understand risk factors, and I think many of our listeners would be familiar with those. But as far as the actual cause, you know, there's been discussion in recent years about, is there a role of the gut microbiome? Is this a prionopathic disorder? What's your take on all of that?  Dr Okun: Yeah, so it's a great question. It's a super-hot area right now of Parkinson. And I kind of take this, you know, apart in a couple of different ways. First of all, when we think about Parkinson disease, we have to think upstream. Like, what are the cause and causes? Okay? So, Parkinson is not one disease, okay? And even within the genes, there's a bunch of different genes that cause it. But then we have to look and say, well, if that's less than 20% depending on who's counting, then 80% don't have a single piece of DNA that's closely associated with this syndrome. And so, what are we missing with environment and other factors? We need to understand not what happens at the end of the process, not necessarily when synuclein is clumping- and by the way, there's a lot of synuclein in the brains normally, and there's a lot of Tau in people's brains who have Parkinson as well. We don't know what we don't know, Dr Jones. And so when we begin to think about this disease, we've got to look upstream. We've got to start to think, where do things really start? Okay? We've got to stop looking at it as probably a single disease or disorder, and it's a circuit disorder. And then as we begin to develop and follow people along that pathway and continuum, we're going to realize that it's not a one-size-fits-all equation when we're trying to look at Parkinson. By the way, for people listening, we only spend two to three cents out of every dollar on prevention. Wouldn't prevention be the best cure, right? Like, if we were thinking about this disease. And so that's something that we should be, you know, thinking about. And then the other is the Global Burden of Disease study. You know, when we wrote about this in a book called Ending Parkinson's Disease, it looked like Parkinson's was going to double by 2035. The new numbers tell us it's almost double to the level that we expected in 2035 in this last series of numbers. So, it's actually growing much faster. We have to ask why? Why is it growing faster? And then we have lots of folks, and even within these issues here within Continuum, people are beginning to talk about maybe these environmental things that might be blind spots. Is it starting in our nose? Is it starting in our gut? And then we get to the gut question. And the gut question is, if we look at the microbiomes of people with Parkinson, there does seem to be, in a group of folks with Parkinson, a Parkinson microbiome. Not in everyone, but if you look at it in composite, there seems to be some clues there. We see changes in Lactobacillus, we see some bacteria going up that are good, some bacteria going down, you know, that are bad. And we see flipping around, and that can change as we put people on probiotics and we try to do fecal microbiota transplantations- which, by the way, the data so far has not been positive in Parkinson's. Doesn't mean we might not get there at some point, but I think the main point here is that as we move into the AI generation, there are just millions and millions and millions of organisms within your gut. And it's going to take more than just our eyes and just our regular arithmetic. You and I probably know how to do arithmetic really well, but this is, like, going to be a much bigger problem for computers that are way smarter than our brains to start to look and say, well, we see the bacteria is up here. That's a good bacteria, that's a good thing or it's down with this bacteria or this phage or there's a relationship or proportion that's changing. And so, we're not quite there. And so, I always tell people---and you know, we talk about the sum in the issue---microbiomes aren't quite ready for prime time yet. And so be careful, because you could tweak the system and you might actually end up worse than before you started. So, we don't know what we don't know on this issue.  Dr Jones: And that's a great point. And one of the themes they're reading between the lines is, we will continue to work on understanding the bio-pathophysiology, but we can't wait until that day to start managing the risk factors and treating patients, which I think is a good point. And if we pivot to treatment here a little bit, you know, one of the exciting areas of movement disorders---and really neurology broadly, I think movement disorders has led the field in many ways---is bioelectronic therapy, or what one of my colleagues taught me is “electroceutical therapy”, which I think is a wonderful term. Dr Okun, when our listeners are hearing about the latest in deep brain stimulation in patients who have movement disorders, what should they know? What are the latest developments in that area with devices? Dr Okun: Yeah. So, they should know that things are moving rapidly in the field of putting electricity into the brain. And we're way past the era where we thought putting a little bit of electricity was snake oil. We know we can actually drive these circuits, and we know that many of these disorders---and actually, probably all of the disorders within this issue of Continuum---are all circuit disorders. And so, you can drive the circuit by modulating the circuit. And it's turned out to be quite robust with therapies like deep brain stimulation. Now, we're seeing uses of deep brain stimulation across multiple of these disorders now. So, for example, you may think of it in Parkinson's disease, but now we're also seeing people use it to help in cases where you need to palliate very severe and bothersome chorea and Huntington's disease, we're seeing it move along in Tourette syndrome. We of course have seen this for various hyperkinetic disorders and dystonias. And so, the main thing for clinicians to realize when dealing with neuromodulation is, take a deep breath because it can be overwhelming. We have a lot of different devices in the marketplace and no matter how many different devices we have in the marketplace, the most important thing is that we get the leads. You know, where we're stimulating into the right location. It's like real estate: location, location, location, whether you've got a lead that can steer left, right, up, down and do all of these things. Second, if you're feeling overwhelmed because there are so many devices and so many settings, especially as we put these leads in and they have all sorts of different, you know, nodes on them and you can steer this way and that way, you are not alone. Everybody is feeling that way now. And we're beginning to see AI solutions to that that are going to merge together with imaging, and then we're moving toward an era of, you know, should I say things like robotic programming, where it's going to be actually so complicated as we move forward that we're going to have to automate these systems. There's no way to get this and scale this for all of the locales within the United States, but within the entire world of people that need these types of devices and these therapies. And so, it's moving rapidly. It's overwhelming. The most important thing is choosing the right person. Okay? For this, with multidisciplinary teams, getting the lead in the right place. And then all these other little bells and whistles, they're like sculpting. So, if you think of a sculpture, you kind of get that sculpture almost there. You know, those little adds are helping to maybe make the eyes come out a little more or the facial expression a little bit better. There's little bits of sculpting. But if you're feeling overwhelmed by it, everybody is. And then also remember that we're starting to move towards some trials here that are in their early stages. And a lot of times when we start, we need more failures to get to our successes. So, we're seeing trials of people looking at, like, oligo therapies and protein therapies. We're seeing CRISPR gene therapies in the laboratory. And we should have a zero tolerance for errors with CRISPR, okay? we still have issues with CRISPR in the laboratory and which ones we apply it to and with animals. But it's still pretty exciting when we're starting to see some of these therapies move forward. We're going to see gene therapies, and then the other thing we're going to see are nano-therapies. And remember, smaller can be better. It can slip across the blood brain barrier, you have very good surface area-to-volume ratios, and we can uncage drugs by shining things like focused ultrasound beams or magnets or heat onto these particles to turn them on or off. And so, we're seeing a great change in the field there. And then also, I should mention: pumps are coming and they're here. We're getting pumps like we have for diabetes and neurology. It's very exciting. It's going to be overwhelming as everybody tries to learn how to do this. So again, if you're feeling overwhelmed, so am I. Okay? But you know, pumps underneath the skin for dopamine, pumps underneath the skin for apomorphine. And that may apply to other disorders and not just Parkinson as we move along, what we put into those therapies. So, we're seeing that age come forward. And then making lesions from outside the brain with focused ultrasound, we're starting to get better at that. Precision is less coming from outside the brain; complications are also less. And as we learn how to do that better, that also can provide more options for folks. So, a lot of things to read about in this issue of Continuum and a lot of really interesting and beyond, I would say, you know, the horizon as to where we're headed.  Dr Jones: Thank you for that. And it is a lot. It can be overwhelming, which I guess is maybe a good reason to read the issue, right? I think that's a great place to end and encourage our listeners to pick up the issue. And Dr Okun, I want to thank you for joining us today. Thank you for such a great discussion on movement disorders. I learned a lot. I'm sure our listeners will as well, given the importance of the topic, your leadership in the field over many years. I'm grateful that you have put this issue together. So, thank you. And you're a busy person. I don't know how we talked you into doing this, but I'm really glad that we did.  Dr Okun: Well, it's been my honor. And I just want to point out that the whole authorship panel that agreed to write these articles, they did all the work. I'm just a talking head here, you know, telling you what they did, but they're writing, and the people that are in the field are really, you know, leading and helping us to understand, and have really put it together in a way that's kind of helped us to be better clinicians and to impact more lives. So, I want to thank the group of authors, and thank you, Dr Jones. Dr Jones: Again, we've been speaking with Dr Michael Okun, guest editor of Continuum's most recent issue on movement disorders. Please check it out. And thank you to our listeners for joining today. Dr Monteith: This is Dr Teshamae Monteith, Associate Editor of Continuum Audio. If you've enjoyed this episode, you'll love the journal, which is full of in-depth and clinically relevant information important for neurology practitioners. Use the link in the episode notes to learn more and subscribe. Thank you for listening to Continuum Audio.

In this episode of the Health Accelerator Community (HAC) through Ageless Future, Regan Archibald explores the root causes of brain fog and cognitive decline, highlighting how chronic stress, poor sleep, and neuroinflammation can impair brain function. He explains the role of the hippocampus in memory and how changes in brain structure, particularly due to aging or conditions like Alzheimer's, can be detected early through symptoms such as forgetfulness, social withdrawal, and diminished focus. Regan discusses how environmental toxins, allergies, and lifestyle stressors disrupt neuroplasticity and outlines the EPIC framework—Emotions, Pain, Infections, Chemicals—as key inflammatory triggers. He introduces actionable strategies to restore brain health, including diagnostic testing, optimizing sleep, exercise, cortisol regulation, targeted nutrients, and innovative peptide and regenerative therapies like cerebrallysin, CMAX, and umbilical cord plasma. Listeners are encouraged to monitor their cognitive clarity over 30 days using wearables and journaling, with an invitation to explore deeper evaluation and support through upcoming retreats and personalized protocols. www.agelessfuture.com

Your neurons can become younger.Your gut can reshape itself in five days.Your immune system can learn to fight cancer.This isn't theory. It's mycology.And it's about to change how you think about what your body can do.This week on Live Well Be Well, I sit down with Dr. Catalina Fernández de Ana Portela, a pioneering mycologist and oncologist who's spent 26 years unlocking the therapeutic power of mushrooms. From Lion's Mane and Reishi to Cordyceps, she's led clinical trials across cancer, autism, neurodegenerative disease, and fertility, quietly reshaping how we think about prevention, healing, and the intelligence of nature.In this episode, we explore:The real science behind Lion's Mane: neuroplasticity, contains GABA, and why your neurons can actually become youngerWhy Lion's Mane may support brain health, gut health, autism, Alzheimer's, multiple sclerosis, and Parkinson's treatmentHow Reishi could help reduce stress and anxiety, and modulate neurotransmitters like GABAThe real science behind putting mushrooms in your coffee (yes, it's more than a trend!)What Cordyceps does for energy, fertility, and performance, and how mushrooms support both male and female reproductive healthBreakthrough research on mushrooms in integrative oncology, including their effects on the gut microbiome and immune systemThe gut-brain axis: how mushrooms can reshape your microbiome in 5 days and support conditions from autism to cancerThe supplement quality crisis: why only 25% of products contain what they claim and how to find trustworthy brandsWhether you're curious about adding Lion's Mane to your morning coffee, wondering if Reishi could actually help your anxiety, or want to understand how mushrooms are being used alongside chemotherapy in clinical trials, this conversation will change how you think about what's possible. The question isn't whether mushrooms work. The science is undeniable. Now it's about finding the right approach for you.Love,Sarah Ann

Medicare Advantage Minute announces 2019 statistics: 17% of MA claims were denied in that year but of those claims that were appealed, 57% were ultimately paid. In the "Your Medicare Benefits 2025" segment we learn how Medicare is likely to cover Monoclonal Antibodies when they are used for the treatment of early onset Alzheimer's disease. "Early onset" is described as symptoms appearing before age 65. Humana subsidiary CenterWell announced the purchase of bankrupt firm The Villages Health. Apparently they declared bankruptcy after discovering they owed hundreds of millions to Medicare. How does this sort of thing sneak up on a company? Finally, as alluded to in the headline of this episode, there was speculation about what might happen if a person insured by a High Deductible Medicare supplement. Would the family members tasked with paying the bills be burdened by extra accounting and check-writing duties in the event of a long period of disability? My answer? Unequivocally no! Contact me at: DBJ@MLMMailbag.com (Most severe critic: A+)                   Visit us on: BabyBoomer.ORG Inspired by: "MEDICARE FOR THE LAZY MAN 2025; Simplest & Easiest Guide Ever!" "MEDICARE DRUG PLANS: A SIMPLE D-I-Y GUIDE" For sale on Amazon.com. After enjoying the books, please consider returning to leave a short customer review to  help future readers. Official website: https://www.MedicareForTheLazyMan.com.

In this podcast we share a few selected highlights from the Alzheimer's Association International Conference (AAIC) day two and day three of the main event in Toronto and Online, 27the - 31st July. -- Dr Connor Richardson, NIHR / Alzheimer's Society Dem Comm Research Fellow from University of Newcastle hosts the show with special guests: Sára Zsadányi, PhD Student at Sant Pau Memory Unit – Neuroimaging Core and Universitat Autonoma de Barcelona Dr Tatiana Giovannucci, Alzheimer's Association Research Fellow Dr Richard Oakley, Associate Director of Research at Alzheimer's Society The AAIC brings together distinguished basic scientists, clinical researchers, early career investigators, clinicians and the care research community at the largest and most influential international conference on dementia science. They share theories and breakthroughs while exploring opportunities to accelerate work and elevate careers. -- Main plenary talks from the day came from Professor Inhee Mook-Jung Seoul National University, Korea with a talk titled "The Gut-Brain Axis in Alzheimer's Disease: Unraveling Pathogenesis and Exploring Novel Therapeutic Strategies" and Dr Juan Fortea, Memory Unit Director — Hospital de la Santa Creu i Sant Pau, Spain with a talk titled "Alzheimer's Disease in Down Syndrome". @alzassociation #aaic25 #aaic -- Find more information on our guests, and a full transcript of this podcast on our website at: https://www.dementiaresearcher.nihr.ac.uk/podcast -- The views and opinions expressed by guests in this podcast represent those of the guests and do not necessarily reflect those of NIHR Dementia Researchers, PIA membership, ISTAART or the Alzheimer's Association.

Aksinya Derevyanko is a postdoctoral researcher in Professor Nicola Allen's lab at Salk. For Derevyanko, recounting her journey from Russia to Spain to San Diego isn't just a practice in storytelling—it's an exercise in what she studies: memory. She watches the connections between our brain cells, called synapses, form, mature, and fail throughout our lifetimes and in diseases like Alzheimer's. Outside the lab? She tests her own synaptic strength by memorizing steps as a semiprofessional dancer.

Forty years ago, the National Institute on Aging launched its Alzheimer disease research center grants program, and the UK Sanders Brown Center on Aging was among the prestigious first class of just 10 awardees. Dr. Greg talks about that designation, the mission of Sanders Brown, and its future with Doctor Linda Van Eldik, director of the UK Sanders Brown Center on Aging.

The Sarepta saga continued into another week as the FDA recommended that the voluntary hold on the company's Duchenne muscular dystrophy gene therapy be lifted for ambulatory patients, after determining that the death of an 8-year-old Brazilian Duchenne patient who had received Elevidys' was not caused by the drug.  Sarepta's stock has swung wildly and its transparency questioned after it elected not to reveal the death of a third patient—a participant in a trial of a gene therapy for limb girdle muscular dystrophy—during a business update last week.    Speaking of entities—or individuals—who have trouble staying out of the news, Health Secretary Robert F. Kennedy Jr. plans to dissolve the U.S. Preventive Services Task Force because it is “too woke.” Also on Monday, Kennedy addressed what he called the “broken” vaccine injury compensation program. Without offering details, he vowed to “fix” the U.S.'s VICP and return it to its “original Congressional intent.”   On the business side of the biopharma house, Q2 earnings are in full swing, with AstraZeneca announcing estimate-beating numbers and CEO Pascal Soriot saying the world “needs to share” in global pharma R&D, while Merck cut $3 billion to support an aggressive launch schedule. Meanwhile, a week ahead of its own earnings report, Novo Nordisk named a new CEO and lowered its 2025 sales guidance for the second time this year.   In clinical development, the Alzheimer's Association Annual Conference is underway in Toronto, with Roche's trontinemab the standout so far. In a Phase Ib/IIa trial, the next-gen anti-amyloid antibody rapidly cleared amyloid from the brains of patients with Alzheimer's disease after just seven months—besting the 18-month timeframe for Biogen and Eisai's Leqembi and Eli Lilly's Kisunla. While Leqembi and Kisunla have shown some progress is slowing down the progression of Alzheimer's, their effect size is modest and they don't work for all patients—leaving plenty of room for symptomatic treatments, such as those being developed by Bristol Myers Squibb and Acadia Pharmaceuticals. The space is gearing up for several readouts, for both symptomatic and disease-modifying therapies alike.   And in BioPharm Executive this week, we dig into the top VC rounds so far this year and highlight a few scrappy biotechs walking the solo road.  

The Silent Killer of the Mind: What You Don't Know About Alzheimer's Could Be Hurting You Already What if the path to Alzheimer's doesn't begin in your 70s—but is already unfolding in your 30s, 40s, or even earlier? In this powerful conversation with Dr. Robert Love, we expose one of the most misunderstood, underestimated health threats of our generation—Alzheimer's disease—and what you can do today to not only prevent it, but potentially reverse its early effects. I've had some of the best minds on this show, but Dr. Love stands out. He's not just brilliant—he's a world-class communicator on a mission to bring hope, tools, and clarity to one of the scariest topics out there: losing your mind. Dr. Love pulls back the curtain on the real causes of Alzheimer's—and it's not just genetics. It's inflammation. It's sugar. It's chronic stress. It's poor sleep. He explains how our modern lifestyle is sabotaging our brain health decades before symptoms appear. And here's what hit me hard: your inflammation levels at age 40 are one of the strongest predictors of your Alzheimer's risk at 70. That's not fear—that's a wake-up call. But the best part? We're not powerless. From simple lifestyle shifts to breakthrough supplements like lion's mane and curcumin, Dr. Love shows us the map to protecting the most vital organ we've got—our brain. We also dive into cutting-edge science that isn't just about prevention—it's about reversal. Dr. Love shares promising new treatments and even clinical results from his medical clinic where Alzheimer's symptoms have improved or stabilized through non-drug protocols. He gives us a first-hand account of a patient who went from disoriented and forgetful to alert, clear, and sharp—all within six months. I'm telling you, this isn't science fiction. This is the new frontier of brain health. Beyond the data and science, what really resonated with me was this: so much of what protects the brain is also what builds a better life—quality sleep, exercise, meaningful learning, low stress, good food, and strong relationships. Dr. Love reminds us that joy, curiosity, and purpose aren't just nice-to-haves—they're biological armor for your brain. And if you're young and thinking this episode doesn't apply to you? Think again. The decisions you make today will echo into the quality of your future decades. Key Takeaways: Alzheimer's starts decades before symptoms appear—your 40s matter Inflammation is one of the biggest risk factors for cognitive decline Sleep, gut health, stress, and sugar all have massive impacts on brain aging Supplements like lion's mane, curcumin, and NMN can support neurogenesis Alzheimer's symptoms can be improved or reversed with lifestyle interventions Your lifestyle is not just shaping your body—it's shaping your brain This one is a must-listen. Share it with someone you love. This information can change lives. — Max Out  

What if we told you your mouth might be the secret key to protecting your brain, your heart… and even your long-term health? This week, we're joined by world-renowned dentist and wellness expert Dr. Jonathan Levine to talk about the connection between oral health and whole-body healing. He breaks down how your gums can warn you about inflammation, why bleeding when brushing isn't normal (even though most people think it is!), and how dental hygiene plays a bigger role in disease prevention than you've ever been told. PLUS, Dr. Levine walks us through his 4-minute protocol to reset your oral health, simple, doable, and science-backed. You'll walk away empowered with tools to take charge of your health… starting with your smile. Tune in, squad!  HEALERS & HEAL LINERS:  Bleeding gums aren't normal: They're an early sign of inflammation and can be a warning flag for more serious issues in the body like cardiovascular disease and Alzheimer's. Don't ignore it—treat the gums, support the body. Oral health impacts systemic health: Your mouth is the gateway to your entire body. Bacteria in the mouth can trigger inflammation that spreads to the brain, heart, and gut. Healing starts with hygiene. Try the 4-minute oral reset: Dr. Levine recommends a simple 4-minute daily routine (electric brushing, flossing, tongue scraping, and using a mouth rinse) to reduce inflammation and protect your whole-body health. -- HEAL SQUAD SOCIALS IG: https://www.instagram.com/healsquad/ TikTok: https://www.tiktok.com/@healsquadxmaria HEAL SQUAD RESOURCES: Heal Squad Website:https://www.healsquad.com/ Heal Squad x Patreon: https://www.patreon.com/HealSquad/membership Maria Menounos Website: https://www.mariamenounos.com My Curated Macy's Page: Shop My Macy's Storefront Prenuvo: Prenuvo.com/MARIA for $300 off EMR-Tek Red Light: https://emr-tek.com/discount/Maria30 for 30% off Airbnb: https://www.airbnb.com/  Join In-Person Heal Retreat Waitlist! https://mariamenounos.myflodesk.com/heal-retreat-waitlist GUEST RESOURCES: Instagram: https://www.instagram.com/drjonlevine/?hl=en Website: https://www.drjonathanlevine.com/  Smile House: https://www.instagram.com/smilehousetribeca/  JBL: https://www.instagram.com/jblnewyorkcity/  If you're in NYC, Dr. Levine is offering one complimentary whitening treatment when you book a Mouth Mapping appointment at Smile House or JBL NYC. Just Mention Heal Squad or Maria's podcast when booking.  Not in the city? Dr. Levine has curated a comprehensive Home Care Guide just for you. Visit @SmileHouseTribeca on Instagram and DM "GUIDE" to receive your free guide! ABOUT MARIA MENOUNOS: Emmy Award-winning journalist, TV personality, actress, 2x NYT best-selling author, former pro-wrestler and brain tumor survivor, Maria Menounos' passion is to see others heal and to get better in all areas of life. ABOUT HEAL SQUAD x MARIA MENOUNOS: A daily digital talk-show that brings you the world's leading healers, experts, and celebrities to share groundbreaking secrets and tips to getting better in all areas of life. DISCLAIMER: This Podcast and all related content (published or distributed by or on behalf of Maria Menounos or http://Mariamenounos.com and http://healsquad.com) is for informational purposes only and may include information that is general in nature and that is not specific to you. Any information or opinions provided by guest experts or hosts featured within website or on Company's Podcast are their own; not those of Maria Menounos or the Company. Accordingly, Maria Menounos and the Company cannot be responsible for any results or consequences or actions you may take based on such information or opinions. This podcast is presented for exploratory purposes only. Published content is not intended to be used for preventing, diagnosing, or treating a specific illness. If you have, or suspect you may have, a health-care emergency, please contact a qualified health care professional for treatment.

Headlines:  – Welcome to Mo News (02:00) – National Chicken Wing Day (02:10) – NYC Mass Shooting (06:30) – Trump Says US Will Set Up Gaza ‘Food Centers' Amid Ongoing Starvation Crisis (12:20) – Sen. Josh Hawley Introduces Bill To Send Tariff Rebate Checks To Americans (21:50) – Trump, Losing Patience With Putin, Says He Will Shorten Deadline to End Ukraine War (27:40) – Ghislaine Maxwell Files Supreme Court Brief Appealing Epstein Conviction (30:45) – Deion Sanders Says He Had Bladder Cancer But Plans to Coach The Colorado Buffaloes This Season (34:00) – Walking Can Reduce the Risk of Alzheimer's, Study Says (36:20) – Goodbye Gentle Parenting, Hello ‘F—Around and Find Out' (38:10) – On This Day In History (45:25) Thanks To Our Sponsors:  – ⁠LMNT⁠ - Free Sample Pack with any LMNT drink mix purchase–⁠ Industrious⁠ - Coworking office. 30% off day pass–⁠ Athletic Greens⁠ – AG1 Powder + 1 year of free Vitamin D & 5 free travel packs– ⁠Incogni⁠ - 60% off an annual plan| Promo Code: MONEWS

Is Zone 2 cardio really the key to longevity and fat loss—or have we been misled? In this solo episode, Louisa challenges the fitness status quo and reveals why low-intensity steady-state cardio might be wasting your time—especially if you're a woman. Drawing on new 2025 research and her deep background in exercise physiology, Louisa explains how men and women respond differently to training, and why higher-intensity workouts may be far more effective for improving mitochondrial health, brain aging, VO2 max, and metabolic flexibility. If you're a woman in your 30s, 40s, 50s, or 60s trying to optimize your longevity, brain function, and body composition—this is a must-listen.  True optimization and longevity never come from comfort alone. You'll learn: Why Zone 2 may not improve mitochondrial health like you think The real training zones that boost VO2 max, fat oxidation & brain function How perimenopausal and menopausal women must train differently The exact weekly routine to optimize longevity, body comp & cognition *** Subscribe to The Neuro Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey. *** A huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts: Troscriptions: Head to www.troscription.com/neuro | Code: NEURO for 10% your first order Boncharge: Head to www.boncharge.com | Code: NEURO15 for 15% off Ketone IQ: Head to www.ketone.com/NEURO for 30% OFF your subscription order + receive a free gift with your second shipment. Manukora: Head to www.manukora.com/neuro to save up to 31% plus $25 worth of free gifts with the Starter Kit. *** I'm Louisa Nicola — clinical neuroscientist — Alzheimer's prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer's risk — and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ *** Topics discussed: 00:00:00: Exercising in zone 2 is a waste of time 00:00:43: Research that shifted her views, especially for women 00:01:41: What Is Zone 2? – Definition and physiology explained 00:02:17: Zone 2 in Practice – How it's measured in real-world settings  00:03:23: Comfort Zone Training – Why Zone 2 is easy but not effective  00:04:16: Elite Athletes vs. The Rest of Us 00:05:10: Why intensity matters more 00:08:11: Time efficiency and real-life experience 00:09:23: Brain Health & Mitochondria – Higher intensity for cognition  00:10:15: Why Zone 2 doesn't have special signaling power  00:12:25: Why higher zones burn fat better  00:13:35: Zones 1 through 5 explained 00:14:00: Zone 5: The Death Zone 00:15:18: Menopause & Muscle Fibers  00:16:55: Lactate Fuels the Brain 00:18:11: How to Train for Longevity – Resistance, intensity, and logic 00:23:59: VO2 Max   00:26:40: Norwegian 4x4 and weekly training strategy  00:30:00: Resistance Training 101 – 5x5 sets, compound lifts, and strength focus  00:31:38: Zone 2 as Recovery – When and how to actually use it 00:33:07: Final Takeaway – Zone 2 isn't bad, but it shouldn't be your priority 

It's no secret in 2025 that stronger muscles lead to longer life. If you're a woman in perimenopause, postmenopause or anything in between, this is no surprise to you. I think we are very aware of it, but let's unpack how weight lifting treats and prevents chronic diseases. Women, at any age, need stronger muscles for a longer life. Not just for aesthetics, but for functionality and independence.   My Guest: A longtime Vanity Fair contributing editor, Michael Joseph Gross has published investigative reporting, essays, and books about culture, technology, politics, religion, and business. He was raised in rural Illinois and lives in New York City.   Questions We Answer in This Episode: [00:04:31] How did this become a topic of interest to you personally?  [00:07:54] Let's connect strength training to prevention and treatment of illnesses often associated - even accepted - with aging? [00:20:17] Weight training has been shown to decrease anxiety and to have positive effects on risk of Alzheimer's or type 3 diabetes, can you explain for the listeners?  [00:26:31] How has the work of Dr. Maria Fiatarone Singh showed that weight training may reduce the risk of Alzheimer's? [00:33:13] Why is lifting heavy important? Do you worry that leading with “lift heavy” intimidates women? What did you uncover as evidence that it is never too late to start progressive strength training?   Why Strength Training? Strength training changes more than just your body—it's internal too. It's not about looking stronger—it's about being stronger. Adolescence and menopause are both times when women feel their bodies are changing without their consent. Strength training gives back a sense of control, capability, and power.   Stronger Muscles Longer Life At Any Age   Strong Youth: Peak bone mass forms in youth—strength training in adolescence builds lifelong health. A 10% increase in bone mass reduces future fracture risk by more than 50%.   Strong in Midlife: Dr. Maria Fiatarone Singh, geriatrician and professor in Sydney, Australia, found that even 90+ year-olds can gain muscle mass with high-intensity training. Weight training can treat and prevent nearly all chronic diseases.   Stronger Muscles Through Weight Lifting Treats and Prevents These Diseases: Type 2 Diabetes Heart Disease Osteoporosis Depression and Anxiety Insomnia Osteoarthritis Frailty Dementia & Alzheimer's Blood Pressure and Cholesterol Fall Risk   Periodization & Smart Strength Training: Periodization: Cycles of high effort, deloading, and rest. Women (especially Type A) tend to push too hard—leading to burnout or injury. Strength training should energize you, not exhaust you. Part of lifting heavy is lifting light. The goal: Live better, not just lift more.   Ancient Greek Lesson: The Right Time to Train Greek word kairos = the “opportune moment” for action. Good training is about doing the right thing at the right time. Don't blindly follow a plan. Train for your body today.   Connect with Michael: Michael's Website Twitter - DuttonBooks   Other Episodes You Might Like: Previous Episode - 5 Things I Would Do If I Were Tired All the Time  More Like This - What's Best Total Body or Split Routine in Menopause   Resources: Tune in to the upcoming Flipping 50 Masterclass. Don't know where to start? Book your Discovery Call with Debra.  

Are we closer to overcoming Alzheimer's disease than most people think?Harvard-trained physician Dr. Joshua Helman exposes how dementia and Alzheimer's stem from multiple interconnected triggers: environmental toxins, chronic stress, inflammation, infections, poor sleep, and even thyroid imbalances.Today, cognitive symptoms are appearing in younger populations at unprecedented rates. Dr. Helman explains how cutting-edge brain imaging and comprehensive functional testing can identify the true mechanisms driving memory loss.You'll also hear about practical, science-backed strategies that can halt or even reverse cognitive decline.Listen now and know that there's hope for you or loved ones suffering from Alzheimer's.Episode Timeline: 00:00 – Episode Overview01:12 – Podcast Intro01:46 – Meet Dr. Joshua Helman03:24 – Why He Focuses on Alzheimer's04:54 – Dementia vs. Alzheimer's06:21 – Can Alzheimer's Be Reversed?07:49 – Deep Sleep: Top Risk Factor08:44 – Early-Onset Alzheimer's in 40s/50s09:25 – How Alzheimer's Is Diagnosed Today10:29 – Thyroid Problems & Brain Health11:37 – Inflammation as an Umbrella Cause13:19 – Brain Damage & Autoimmune Testing14:18 – Diet and Brain Vessel Damage15:11 – Plant-Based Eating & DHA Sources16:57 – Stress as a Major Trigger18:08 – Stress Relief & Social Connection20:26 – Fasting for Brain Health23:48 – Gut Inflammation & Refeeding After Fasting27:24 – Toxins & Plastics in the Brain30:11 – Aluminum, Heavy Metals & Alzheimer's31:32 – Hope for Advanced Cases33:08 – Personalized Treatments & Plasma Exchange34:33 – Functional Testing for Toxins & Infections36:21 – Viruses, Lyme & Dementia Risk38:16 – Multi-Therapy Approach for Alzheimer's39:23 – Oxygen Therapy & BDNF Benefits40:55 – How to Connect with Dr. Helman42:22 – Podcast Outro42:47 –Post-Episode Takeaways About Dr. Joshua Helman:Dr. Joshua Helman, MD is a Harvard-trained physician licensed in 14 states. He holds two degrees in biochemistry, a bachelor's degree (magna cum laude) from Harvard and a master's degree from the University of Cambridge, UK. His medical degree is from Harvard Medical School and MIT. He is board certified by the American Board of Emergency Medicine and the American Board of Lifestyle Medicine. He is the former and current medical director of Hippocrates Health Institute, as well as Chief Medical Officer of 2 different Alzheimer's Reversal Centers: BrainPower Clinics and Alzheimer's Treatment Centers of America. He has worked at the TrueNorth Health Center with a focus on fasting.He recently launched a weekly podcast called Alzheimer's Breakthrough, and his areas of interest span longevity, regeneration, vitality, toxins, mold, Lyme disease, energy medicine and breathwork. With a passion for applying biochemical knowledge to r Do You Want Help Saving Your Thyroid? Click Here to access hundreds of free articles and blog posts. Click Here for Dr. Eric's YouTube channel Click Here to join Dr. Eric's Graves' disease and Hashimoto's group Click Here to take the Thyroid Saving Score Quiz Click Here to get all of Dr. Eric's published booksClick Here to work with Dr. Eric

Former Wisconsin Governor and author of the insightful book, "My Two Elaines," Marty Schreiber, returns to the Fading Memories podcast to share his powerful personal experience as a caregiver for his wife Elaine throughout her nearly two-decade battle with Alzheimer's disease. This episode delves into the critical understanding that while Alzheimer's is terrible, ignorance of the disease is worse, emphasizing the vital need for knowledge and empathy in Alzheimer's care. Marty reflects on the evolution of his relationship with Elaine as her dementia progressed, highlighting the profound and necessary shift towards "joining her world." He discusses the importance of communication strategies for Alzheimer's, including the concept of "therapeutic fibbing," to enhance the quality of life for those living with memory loss.    In this heartfelt conversation about Alzheimer's caregiving, Marty also addresses: Practical advice on how to communicate with someone with Alzheimer's. The significance of caregiver self-care and overcoming the reluctance to ask for help. Finding moments of connection and joy amidst the challenges of caring for someone with Alzheimer's. Understanding the unique grief experienced by Alzheimer's caregivers. Guidance for new caregivers seeking to navigate the complexities of caring for a loved one with dementia. Marty also shares updates from the re-released "My Two Elaines," featuring new perspectives on the Alzheimer's journey. Join us for an episode filled with invaluable insights and compassionate guidance for anyone touched by Alzheimer's and the demanding role of dementia caregiving. Our Guest: Governor Martin Schreiber Marty Schreiber is a former Wisconsin Governor. Moreover, he authored "My Two Elaines." This book shares his caregiving journey. Specifically, it details his time with his wife Elaine. She lived with Alzheimer's. Marty offers profound insights. Furthermore, he emphasizes understanding the disease. He believes ignorance is worse. Consequently, he shares vital lessons. These help caregivers connect with loved ones. For instance, he discusses "joining their world." He also touches on "therapeutic fibbing." Ultimately, Marty's story offers hope. It provides practical guidance for navigating Alzheimer's. +++++++++++++++++ Related episodes: Caregiver Founders: Building Resources for Support Caregiver Struggles – A Supportive Alzheimer's Novel ++++++++++++++++++++++++++++++++++++++++ Sign Up for more Advice & Wisdom - email newsletter. Please help us keep our show going by supporting our sponsors. Thank you. ++++++++++++++++++++++++++++++++++++++++ Make Your Brain Span Match Your LifeSpan Relevate from NeuroReserve With Relevate nutritional supplement, you get science-backed nutrition to help protect your brain power today and for years to come. You deserve a brain span that lasts as long as your lifespan. ++++++++++++++++++++++++++++++++++++++++ Feeling overwhelmed? HelpTexts can be your pocket therapist. Going through a tough time? HelpTexts offers confidential support delivered straight to your phone via text message. Whether you're dealing with grief, caregiving stress, or just need a mental health boost, their expert-guided texts provide personalized tips and advice. Sign up for a year of support and get: Daily or twice-weekly texts tailored to your situation Actionable strategies to cope and move forward Support for those who care about you (optional) HelpTexts makes getting help easy and convenient. ++++++++++++++++++++++++++++++++++++++++ List of the Top 20 Alzheimer's Podcasts via FeedSpot! See where we rank. Join Fading Memories On Social Media! If you've enjoyed this episode, please share this podcast with other caregivers! You'll find us on social media at the following links. Instagram LinkedIn  Facebook Contact Jen at hello@fadingmemoriespodcast.com

This week's episode has the cohosts talking about social isolation and earlier death among the elderly population.   Studies have shown that loneliness is associated with a higher risk of mortality in older adults. For example, one study found that individuals experiencing loneliness at one or more points in time had a higher hazard for mortality compared to those who never experienced loneliness.  Loneliness can trigger physiological stress responses, potentially leading to chronic inflammation and reduced immunity. These factors can contribute to the development of various health problems, including heart disease, Alzheimer's, and other age-related illnesses.  Social isolation, which is closely linked to loneliness, can limit access to social support, including assistance with daily tasks, emotional support, and healthcare. This lack of support can negatively impact both physical and mental well-being.  Loneliness and social isolation have also been linked to poorer cognitive function and an increased risk of conditions like dementia.  Conversely, research suggests that maintaining social connections and receiving regular visits from loved ones can mitigate the risks associated with loneliness and potentially increase longevity.  In essence, according to many studies prior to 2025, loneliness can create a cycle of negative health impacts, potentially increasing the risk of premature death, while social connections and support can act as protective factors.  HOWEVER.... a new study was just reported last month that questions the previous assumptions.  Researchers tracking home care recipients in Canada, Finland, and New Zealand discovered something unexpected: lonely older adults were actually less likely to die within a year compared to their non-lonely peers. Among the most vulnerable seniors — those receiving help at home with daily activities — being lonely was associated with an 18% to 23% lower risk of death. We are sure more research will now be done to either support the newest study or previous studies.  Time will tell!

They always say you need to exercise a lot and eat healthier to stay healthy and a recent story in the Star Tribune featuring findings from the Alzheimer's Association discusses just that so we talked to Dr Joseph Gaugler, Chair in Long Term Care and Aging with the University of Minnesota School of Public Health who is currently at the conference joins Jason to discuss these findings when it comes to those looking to age better and healthier!

Unlock the secrets of male well-being with Christos Konstantinidis, the pioneering founder and CEO of Adam Health, as we unveil the profound link between erectile health and holistic male wellness. Discover how your body's signals, often overlooked, could be the earliest indicators of serious health concerns like cardiovascular disease. Christos provides enlightening insights into how erectile function serves as a critical health barometer, cutting across cardiovascular, neurological, and hormonal domains.Explore the natural phenomena of nighttime erections and their vital role in sustaining erectile health, as well as the promise held by erectile dysfunction drugs in potentially extending lifespan and reducing the risk of chronic illnesses such as Alzheimer's. With Christos's expert guidance, learn about groundbreaking tools like Adam Health's erection health tracker, designed to empower men in managing their sexual health proactively. Don't miss out on the array of solutions available to tackle erectile issues, from PDE5 inhibitors to cutting-edge rejuvenation treatments, all aimed at improving quality of life and fostering an open dialogue about men's health.https://talktoadam.comLies I Taught In Medical School : Free sample chapter- https://www.robertlufkinmd.com/lies/Complete Metabolic Heart Scan (20% off 'LUFKIN20') https://www.innerscopic.com/Fasting Mimicking Diet (20% off) https://prolonlife.com/Lufkin At home blood testing (20% off) https://siphoxhealth.com/lufkinMimio Health (15% off 'LUFKIN') https://mimiohealth.sjv.io/c/5810114/2745519/30611 Web: https://robertlufkinmd.com/X: https://x.com/robertlufkinmdYoutube: https://www.youtube.com/robertLufkinmdInstagram: https://www.instagram.com/robertlufkinmd/LinkedIn: https://www.linkedin.com/in/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinThreads: https://www.threads.net/@robertlufkinmdFacebook: ...

More than 20 million U.S. adults live with chronic neocortical brain damage caused by stroke, Alzheimer's, or traumatic injury—conditions with few effective treatments. A new research initiative aims to change that by using regenerative medicine to repair damaged brain tissue and restore lost function. Joining us to explain the science and the vision behind the program is Jean Hebert, Program Manager for Health Science Futures at the Advanced Research Projects Agency for Health.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Sandra Burns from Joe's Farm Crisps tells Paul how a working Cork farm turned five acres of sunflowers into one of the season's most joyful days out that also helps people with Alzheimer's Hosted on Acast. See acast.com/privacy for more information.

In this podcast we share a few selected highlights from the Alzheimer's Association International Conference (AAIC) first and second day of the main event in Toronto and Online, 27the - 31st July. -- Dr James Brady, Postdoctoral Research Fellow at University of Tasmania hosts the show with special guests: Dr Lucy Stirland, Academic Old Age Psychiatrist at The University of Edinburgh Dr Isabel Castanho, Instructor at the Beth Israel Deaconess Medical Center (BIDMC), Harvard Medical School Felix Wittmann, Research Fellow & PhD candidate at Leipzig University -- The AAIC brings together distinguished basic scientists, clinical researchers, early career investigators, clinicians and the care research community at the largest and most influential international conference on dementia science. They share theories and breakthroughs while exploring opportunities to accelerate work and elevate careers. Main plenary talks from the day came from Professor Katerina Akassoglou, University of California, San Francisco, United States exploring Neurovascular Interactions in Alzheimer's Disease: From Mechanisms to Treatments + Professor Maria Grazia Spillantini, from University of Cambridge United Kingdom for her plenary titled 'The Multiple Facets of Tau Pathology'. -- #AAIC25 @alzassociation -- Find more information on our guests, and a full transcript of this podcast on our website at: https://www.dementiaresearcher.nihr.ac.uk/podcast -- The views and opinions expressed by guests in this podcast represent those of the guests and do not necessarily reflect those of NIHR Dementia Researchers, PIA membership, ISTAART or the Alzheimer's Association.

Good morning from Pharma and Biotech daily: the podcast that gives you only what's important to hear in Pharma e Biotech world. GSK has entered a partnership with Hengrui worth up to $12 billion, focusing on the COPD candidate HRS-9821. The FDA's new voucher policy has caused confusion among experts, as it lacks clear definition and was announced without public input. The American Medical Association urges RFK Jr. to maintain the preventive task force, and Sarepta denies a patient death is linked to Elevidys as the FDA launches a probe. Biopharma companies are leaning towards holistic treatments for Alzheimer's, while Atai-partnered schizophrenia drug fails in a mid-stage trial. Boehringer partners with Irish startup Re-Vana in a $1 billion+ eye deal.As the Alzheimer's space becomes more competitive, biopharma companies are focusing on holistic treatments beyond disease-modifying drugs like Leqembi and Kisunla. Companies such as Bristol Myers Squibb, Acadia, Otsuka, and Lundbeck are renewing their search for symptomatic treatments. Five upcoming data drops could potentially lead to more effective therapies for Alzheimer's. Sarepta Therapeutics is facing challenges due to safety concerns surrounding its gene therapies, leading to a drop in stock value. The FDA's new voucher program aims to offer accelerated pathways for drugs meeting certain criteria, but experts criticize the lack of transparency and public input in the policy's announcement. Sarepta's future is uncertain as the FDA considers a new study for Elevidys, and the EU issues a negative opinion on the drug. Other news includes delays in the FDA decision on GSK's Blenrep, AstraZeneca's PIII win with nanobody treatment for myasthenia gravis, and the removal of thimerosal from influenza vaccines. George Tidmarsh has been appointed as the new chief of FDA's CDER.

In this episode, Nick talks about The Big Beautiful Deal with the EU, Dems Falling Lower, Two Marines Stop Stabber, A Pilot Perp Walk, Bronson, Someone Getting Lippy and Alzheimers!  Watch Nick on the FREE RUMBLE LIVE LINEUP at 6pm ET https://rumble.com/TheNickDiPaoloShow TICKETS - Come see me LIVE! For tour dates and tickets -  https://nickdip.com MERCH - Grab some snazzy t-shirts, hats, hoodies,mugs, stickers etc. from our store! https://shop.nickdip.com/ SOCIALS/COMEDY-  Follow me on Socials or Stream some of my Comedy -  https://nickdipaolo.komi.io/

Anti-aging expert Dr Rhonda Patrick reveals how magnesium, HIIT workouts, creatine, and vitamin D can prevent disease, slow aging, and boost brain power - starting today.  Dr. Rhonda Patrick is a PhD biomedical scientist, expert in aging, nutrition, and metabolism, and founder of FoundMyFitness. She produces a monthly series of in-depth, science-focused podcasts exploring actionable strategies for enhancing longevity, cognitive performance, and physical health. She explains: Why cardiovascular fitness is the #1 predictor of lifespan The groundbreaking science behind rejuvenating your heart by 20 years How small daily habits can cut your risk of Alzheimer's and cancer The hidden link between mitochondrial health, aging, and chronic disease 00:00 Intro 02:17 My Mission to Improve People's Health 03:50 What Impact Will Rhonda's Research Have on People? 05:22 The Role of Genetics in Aging vs. Lifestyle 07:36 Lifestyle and Life Expectancy 10:06 The Future of Aging, Longevity, and Gene Therapy 15:28 Death-Related Risks of Being Sedentary 22:30 How to Improve Your Cardiorespiratory Fitness 25:45 Best Workout Routine to Improve Cardio Health 30:14 Norwegian 4x4 Training Explained 32:41 How the Body Generates Energy and Exercise Intensity 38:28 Why We Can't Drink Lactate and the Effects of Vigorous Training 42:33 How to Reduce Cognitive Decline 47:11 What Causes Dementia and Alzheimer's 53:09 Do Multivitamins Improve Cognitive Performance? 01:00:26 70% of the U.S. Population Is Vitamin D Deficient 01:03:12 Vitamin D Deficiency and Increased Risk of Dementia 01:14:41 How the Keto Diet Affects Life Expectancy and Healthspan 01:19:43 Exogenous Ketones and Cognitive Repair 01:24:06 Recommended Superfoods 01:26:46 Omega-3: Effects on Mental Health, Depression, and Longevity 01:32:21 Is Omega-3 Supplementation the Same as a High Omega-3 Diet? 01:41:28 Effects of Creatine on Cognitive Function 01:49:18 Link Between Cancer Outcomes and Creatine 01:50:09 Does Creatine Cause Hair Loss? 01:59:06 Fasting Windows to Achieve Autophagy 02:01:01 Intermittent Fasting: Do's and Don'ts 02:02:19 Effects of Fasting on Sleep 02:04:49 How Soon After Training Should You Take Protein? 02:08:29 What Is Insulin Resistance? 02:10:28 Benefits of Red Light Therapy 02:11:36 Infrared vs. Traditional Saunas 02:18:41 Sauna Benefits: Reducing Stress and Improving Mood 02:22:12 What Are Microplastics and Are They Harmful? 02:27:48 The Role of Fiber in Eliminating Microplastics 02:31:43 Are There Risks to Living Near a Golf Course? 02:42:18 What Is Choline? Follow Dr Rhonda: Instagram - https://bit.ly/3TYAEUD X - https://bit.ly/3IFvCu1  Website - https://bit.ly/4o75U1F  Weekly health newsletter - https://bit.ly/4kYsR4f  You can subscribe to Rhonda's monthly series on YouTube and Spotify: YouTube: https://bit.ly/4l1FZW9  Spotify: https://bit.ly/45l77Lc  You can download Rhonda's free protocol guides, here: The Cognitive Enhancement Blueprint - https://bit.ly/44QYF6t  The Omega-3 Supplementation Guide- https://bit.ly/44Pi1sE  How to Train According to the Experts - https://bit.ly/4mbtzMm  Research Document: https://stevenbartlett.com/wp-content/uploads/2025/07/DOAC-Dr-Rhonda-Patrick-Independent-Research-further-reading.pdf The Diary Of A CEO: ⬜️Join DOAC circle here - https://doaccircle.com/  ⬜️Buy The Diary Of A CEO book here - https://smarturl.it/DOACbook  ⬜️The 1% Diary is back - limited time only: https://bit.ly/3YFbJbt  ⬜️The Diary Of A CEO Conversation Cards (Second Edition): https://g2ul0.app.link/f31dsUttKKb  ⬜️Follow Steven - https://g2ul0.app.link/gnGqL4IsKKb  Sponsors: Intuit - https://www.intuit.com/expert-careers/?cid=aud_nativly_reach_us_expertnetwork-fy25_aw_hostread-diaryofceo-na-60s_broad_audio_1x1_intuit-gtm_na_na   KetoneIQ - Visit https://ketone.com/STEVEN for 30% off your subscription order Learn more about your ad choices. Visit megaphone.fm/adchoices

We'll tell you what President Donald Trump and UK Prime Minister Keir Starmer spoke about in their meeting today. Plus, Trump once again didn't rule out a pardon for Jeffrey Epstein associate, Ghislaine Maxwell. The Trump administration says sweeping changes are on the horizon at the Federal Reserve. "Tesla Takedown" protestors have a new target. And, the daily habit that could cut down the risk of Alzheimer's. Learn more about your ad choices. Visit podcastchoices.com/adchoices

The extreme heat is expected in the Midwest, the Southeast and some parts of the Northeast. Heat alerts will remain in effect through Wednesday night in some places. President Trump and the head of the EU have reached a trade agreement. The details and who wins and who loses in the deal. News in the world of Alzheimer's treatment. The new drug that could change the way cognitive decline is diagnosed and treated. "Eye on America"...meet the woman trying to solve food insecurity one act of kindness at a time. To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices

Send me a text! I'd LOVE to hear your feedback on this episode!My guest is Dr. Bruce Dorr, MD, OBGYN & Senior Medical Advisor for Biote.  We talk menopause & also discuss the article from the NY Times released on February 1, 2023 Women Have Been Misled About Menopause.The conversation around menopause is changing dramatically, but are women getting accurate information about what's actually happening in their bodies? Dr. Bruce Dorr, a board-certified OBGYN specializing in hormone optimization, joins Sandy to challenge widespread misconceptions and reveal what many women aren't being told about their changing hormones.This eye-opening discussion ventures far beyond hot flashes to explore how hormone imbalances affect virtually every bodily system. Dr. Dorr explains the shocking finding that joint pain—not hot flashes—tops the list of menopausal symptoms, and why so many women mistakenly attribute their discomfort to "just getting older." You'll discover the critical connection between hormone levels and brain health, including recent research linking hot flash severity to brain lesions similar to those found in Alzheimer's disease.The conversation tackles the infamous Women's Health Initiative study that scared millions away from hormone therapy, with Dr. Dorr clarifying why bioidentical hormones differ fundamentally from synthetic options. He offers a compelling analogy: "Not all estrogen is the same—it's like comparing ethanol to methanol. Both are alcohol, but one helps you feel good while the other can kill you." This distinction proves crucial for women weighing their treatment options.Most powerfully, Dr. Dorr addresses why standard medical care often fails menopausal women, with 60% of OBGYNs prescribing antidepressants rather than addressing hormonal root causes. He explains how pellet therapy works as an alternative delivery system and shares stories of patients whose lives were transformed once their hormones were properly balanced. If you're navigating perimenopause or menopause—or simply want to understand what lies ahead—this conversation provides essential information for making informed decisions about your health and vitality.Support the showPlease rate & review my podcast with a few kind words on Apple or Spotify. Subscribe wherever you listen, share this episode with a friend, and follow me below. This truly gives back & helps me keep bringing amazing guests & topics every week.Instagram: https://www.instagram.com/sandyknutrition/Facebook Page: https://www.facebook.com/sandyknutritionTikTok: https://www.tiktok.com/@sandyknutritionYouTube: https://www.youtube.com/channel/UCIh48ov-SgbSUXsVeLL2qAgRumble: https://rumble.com/c/c-5461001Linkedin: https://www.linkedin.com/in/sandyknutrition/Substack: https://sandykruse.substack.com/Podcast Website: https://sandykruse.ca

Topics explored in this episode include:The Nervous System through the lens of Polyvagal TheoryHow to expand your Window of Wellness & ResilienceThe impact of lonelinessTrauma healing & addiction recoveryCo-regulation & the power of communityPractices for Vagal ToningDr. Ilene Naomi Rusk received her PhD in Psychology (Neuropsychology and Psychopharmacology) in the UK with a focus on the brain circuitry involved in appetite regulation, motivation, and satiation. In Canada she completed fellowships in neuroscience + neuropsychology looking at novel treatment strategies for Alzheimer's Disease and neuropsychiatric issues. Dr Rusk was the Parkinson's Disease Fellow for Canada and she worked collaboratively with pharmaceutical companies authoring numerous peer-reviewed articles in neuroscience & treating brain and behavior disorders.  She is trained in somatic approaches to healing trauma and nervous system disorders, and uses numerous trauma resolution techniques (EMDR and Brainspotting, among them). Training in cognitive rehabilitation adds to her healing repertoire. Dr Rusk's extensive trainings in Polyvagal Theory has led her incorporate vagal toning into her work with patients with anxiety, depression and stress sensitivities. She draws from decades of experience in ancestral healing, yoga, breathwork  +  mindfulness practices and uses them as an integral part of her functional nervous system health program. Spiritual guidance is intrinsic to her work.Dr. Rusk co-founded the Brain and Behavior Clinic in Boulder, CO and developed the Healthy Brain Program. While training in a functional medicine approach to cognitive + emotional health, she developed a team-based program to integrate functional and personalized brain health with trauma healing work to optimize stress resilience, anxiety and mental health. She is former Director of Community Medical Education for Grillo Health Information Resource Center and the Director of Resilience Training with Disaster Resources an international organization dedicated to healing anxiety, stress + distress in educators, children and families after natural and man-made disasters. Dr. Rusk's work focuses on blending personalized integrative healthcare and psychological wellness within a scientist-practitioner model. She has woven spirituality and mindfulness into her practice for over 35 years, and leads monthly online Embodied Brain Polyvagal Groups. To learn more & join Dr Rusk's next Vagal Toning Practice Group visit: https://www.ilenenaomirusk.com/events__Access a free mindfulness meditation guided by Mary Tilson to help manage cravings and regulate emotions: https://pages.sunandmoonsoberliving.com/easemeditationFollow along on Instagram: @sunandmoon.soberliving __Disclaimer: The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment.

In today's episode, we had the great opportunity to speak with an amazing author who is changing the outlook on aging! Dr. Corinne Auman, a care management expert and author of "Keenagers: Telling a New Story About Aging," joins us to challenge the overwhelming negativity surrounding the aging process.Drawing from both professional expertise and personal experience caring for family members with dementia and Parkinson's, Dr. Corinne reveals a profound truth: how we think about aging largely determines how our aging journey unfolds. Those with positive attitudes toward their later years tend to prepare comprehensively, not just financially but emotionally, socially, physically, and spiritually. Meanwhile, those dreading age-related decline often avoid planning altogether, inadvertently creating the very crises they fear.The language we use matters deeply. When searching for words to describe aging positively while writing her book, Dr. Corinne discovered our vocabulary is dominated by negative terms. This linguistic limitation reflects and reinforces our cultural attitudes. "Keenagers"—older adults who are highly developed and maintain strong interests—offers a fresh alternative that celebrates continued engagement rather than withdrawal.For caregivers, especially, this perspective shift is transformative. Whether you're currently caregiving or simply wanting to approach your future with greater intention, Dr. Corinne's insights will inspire you to write a new story about aging—one filled with purpose, possibility, and continued growth.Have you started planning for your aging journey? To learn more about Dr. Auman, visit corinneauman.com. Host:  ⁨J Smiles Comedy⁩ Producer: Mia Hall⁩ Editor: Annelise Udoye#CaregivingJourney#DementiaAwareness#AlzheimersCare#CaregiverSupport#HumorInCaregiving#EndAlz #keenagers #aging #olderadults Support the show"Alzheimer's is heavy but we ain't gotta be!"IG: https://www.instagram.com/parentingupFB: https://www.facebook.com/parentingupYT: https://www.youtube.com/channel/UCDGFb1t2RC_m1yMnFJ2T4jwPatreon: https://patreon.com/jsmilesstudiosTEXT 'PODCAST" to +1 404 737 1449 - to give J topic ideas, feedback, say hi!Be sure to leave us a review!

What if YOU’RE the problem? Dun dun dun!

It's a bird ... It's a plane ... It's our Superman episode!! Join Kaiti and Phil as they discuss the new James Gunn Superman movie. Hear what we liked, what we didn't like and most importantly we debate each others opinions. Test your Superman knowledge with a quiz all about our favorite Kryptonian. We also take a rabbit whole to the Wizarding World and discuss our thoughts and feelings about the castings for the upcoming HBO Harry Potter series. Let's just say, we have strong opinions! So, feed/water Krypto, dawn your capes, put your underwear on the outside of your uniform and press play on this out of this world episode of Muggle with a Mic!For information on the Alzheimer's Association:alz.orgSupport our Walk Team here:https://act.alz.org/site/TR?team_id=945420&pg=team&fr_id=18816For more information on Final Boss Con:finalbosscon.comHelp support us by listening to episodes, liking posts, sharing our episodes with friends and family and subscribing on all the social media platforms including YouTube! All of these forms of support are free and easy to do but very much appreciated!Find more Muggle with a Mic content and YouTube videos here: linktr.ee/mugglewithamicMusic from this episode: "Take a Chance", Kevin MacLeod (incompetech.com) Licensed under Creative Commons

In today's episode, Dr. John E. Lewis, a nutrition expert and researcher, dives deep into the science of brain health, cognitive function, and preventing Alzheimer's. Dr. Lewis explores how exercise, nutrition, and polysaccharides play a crucial role in optimizing brain performance and longevity. Tune in to learn: ·       What polysaccharides are and their impact on brain health

Mini-brains in space. Did you know that we can study something called brain organoids, effectively mini-brains, in the special conditions in space, on the International Space Station, and that such studies may help us with diseases like Alzheimers, Autism or Parkinsons? My guest this week is Prof. Alysson Muotri from the University of California San Diego. He and his team have flown such brain organoids to the ISS many times already. Don't miss this episode on what I consider one of the most exciting intersections of space and biology, and ultimately a potential source of massive positive impact right here on Earth!

Rhonda Patrick, Ph.D. (@foundmyfitness) is a biomedical scientist and the founder of FoundMyFitness, a platform dedicated to delivering rigorous, evidence-based insights on improving healthspan and mitigating age-related diseases.Sponsors:Helix Sleep premium mattresses: https://HelixSleep.com/Tim (27% off all mattress orders)Momentous high-quality creatine and other supplements: https://livemomentous.com/tim (code TIM for up to 35% off)David Protein Bars 28g of protein, 150 calories, and 0g of sugar: https://davidprotein.com/tim (Buy 4 cartons, get the 5th free.)Monarch Money track, budget, plan, and do more with your money: MonarchMoney.com/Tim (50% off your first year at monarchmoney.com with code TIM)Timestamps:[00:00:00] Start.[00:04:54] Dealing with aging parents and other topics on the table.[00:10:43] How a common multivitamin helps reverse cognitive and memory aging.[00:12:04] The importance of supplementation — especially as we age.[00:13:10] Effectively supplementing with omega-3 fish oil to counter APOE4 and Alzheimer's risks.[00:16:50] The CoQ10 and omega-3 protocol that has helped Rhonda's father manage Parkinson's symptoms for nearly a decade.[00:19:28] Sulforaphane: a potent NRF2 activator with an unexpected benefit for Rhonda's mother's tremors.[00:25:34] How Rhonda convinced her mom to start CrossFit and the power of community-based, senior-focused fitness.[00:26:52] The earlier the intervention, the better the outcomes.[00:32:25] Intermittent fasting vs. extended fasting and my own results.[00:44:31] Does fasting destroy muscle mass? Debunking the catabolism fear and understanding the crucial role of the re-feeding phase.[00:57:24] "Dirty" fasting: what really happens to autophagy and metabolic benefits when you add a splash of cream or MCT oil to your coffee?[01:00:44] VO2 max: the one metric that may predict lifespan more accurately than anything else, and how we work to improve it.[01:12:07] How a two-year exercise program reversed heart aging by 20 years in previously sedentary, middle-aged adults.[01:16:18] Lactate isn't the enemy: how vigorous exercise creates a superfuel that protects and grows the brain.[01:20:30] The optimal sauna protocol (temperature and frequency) for slashing dementia risk by 66%.[01:29:17] If you're human, you'll find a use for curcumin.[01:30:43] Creatine for cognition: moving beyond the gym with a powerful, science-backed tool for focus and combating sleep deprivation.[01:42:41] Still vitamin D deficient despite taking supplements? Here's the critical cofactor you're probably missing.[01:53:52] Shocking sources of microplastics in our daily lives, including chewing gum and teabags.[02:04:10] The uncomfortable truth about "moderate" alcohol consumption, cancer risk, and why the "sick quitter" hypothesis makes most older studies unreliable.[02:17:03] The ups and downs of ketamine and psilocybin on cognition and longevity.[02:24:19] Parting thoughts and where to find more from Rhonda.*Show notes for this episode: https://tim.blog/2025/07/24/dr-rhonda-patrick/For show notes and past guests on The Tim Ferriss Show, please visit tim.blog/podcast.For deals from sponsors of The Tim Ferriss Show, please visit tim.blog/podcast-sponsorsSign up for Tim's email newsletter (5-Bullet Friday) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Discover Tim's books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissYouTube: youtube.com/timferrissFacebook: facebook.com/timferriss LinkedIn: linkedin.com/in/timferrissSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

On this episode of The Doctor Hyman Show, I sit down with Dr. Eric Topol—renowned cardiologist, geneticist, and founder of the Scripps Research Translational Institute—to talk about the future of disease prevention. From AI diagnostics to genetic risk scoring, we explore the tools that could help stop Alzheimer's and other chronic diseases before they start. This is one of the most hopeful conversations I've had about what's ahead. Watch it on YouTube here. We discuss: • How new diagnostics and AI tools could help detect Alzheimer's early • The key lab tests and biomarkers to know—and how to talk to your doctor about them • Why tracking your health data over time matters more than you think • What you can do to strengthen your immune system and lower disease risk We have more power than ever to take control of our health. This episode shows you where to start. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman's Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Resultshttps://drhyman.com/pages/hyman-hive This episode is brought to you by Seed, Pique, fatty15 and AirDoctor. Visit seed.com/hyman and use code 25HYMAN for 25% off your first month of Seed's DS-01® Daily Synbiotic. Receive 20% off FOR LIFE + a free Starter Kit with a rechargeable frother and glass beaker at Piquelife com/Hyman. Head to fatty15.com/hyman and use code HYMAN for 15% off your 90-day subscription Starter Kit.Get cleaner air. Right now, you can get up to $300 off at airdoctorpro.com/drhyman.