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Wie geht es eigentlich der Sexualität von Männern? Oft wird sie auf Leistung, Potenz und „Funktionieren“ reduziert – doch männliche Sexualität ist weitaus facettenreicher. In dieser Folge sprechen wir über Mythen, Herausforderungen und die Bedeutung von sexueller Gesundheit für Männer und warum die "Alpha-Male" Bewegung niemandem gut tut. ✨ Themen in dieser Episode: ✔️ Was bedeutet sexuelle Gesundheit für Männer? ✔️ Der Einfluss von Stress, Alter und Lebensstil auf die Sexualität ✔️ Erektionsprobleme, Lustlosigkeit & andere Tabuthemen – was steckt dahinter? ✔️ Männlichkeit, Emotionen und Sexualität – ein gesellschaftlicher Blick ✔️ Praktische Tipps für eine gesunde und erfüllte Sexualität
Allyson with a Y. Ocean with two Ls. And zero chill when it comes to changing the face of cancer care. Dr. Allyson Ocean has been quietly—loudly—at the center of every major cancer breakthrough, nonprofit board, and science-backed gut punch you didn't know you needed to hear. In this episode, she joins me in-studio for a conversation two decades in the making. We talk twin life, genetics, mitochondrial disease, and why she skipped the Doublemint Twins commercial but still ended up as one of the most recognizable forces in oncology. We cover her nonprofit hits, from Michael's Mission to Let's Win Pancreatic Cancer to launching the American Jewish Medical Association—yes, that's a thing now. We get personal about compassion in medicine, burnout, bad food science, and microplastics in your blood. She also drops the kind of wisdom only someone with her résumé and sarcasm can. It's raw. It's real. It's the kind of conversation we should've had 20 years ago—but better late than never.RELATED LINKS:– Dr. Allyson Ocean on LinkedIn– Let's Win Pancreatic Cancer– NovoCure Leadership Page– Michael's Mission– American Jewish Medical Association– The POLG Foundation– Cancer Buddy App (Bone Marrow and Cancer Foundation)– Dr. Ocean at OncLiveFEEDBACK:Like this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship inquiries, email podcast@matthewzachary.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Stay tuned to the end of the episode for a policy update on the bill containing Medicaid cuts that is making its way through Congress, and the recent MAHA Commission Report. If you were to ask any healthcare leader what the top challenges in our industry are, it's a fair bet that “improving patient access to care” would be on the list. There have been so many investments made in the industry to improve access—especially since the Covid-19 pandemic. With this level of investment, we should be moving the needle. But the data shows that access is not getting better, and in some cases, it's getting worse. This week, Advisory Board physician and medical group expert Mahaya Walker joins host Abby Burns to unpack why, and what medical groups can do about it. They break down Advisory Board research findings around how a narrow focus on improving appointment availability may actually be hurting efforts to improve access, and how medical groups can move the needle on access by putting clinicians closer to the center of their access strategies. Links: Provider availability: A new way to measure access for medical groups Top 3 opportunities to save provider time on administrative tasks Ambulatory access: How to make sustainable progress How to reduce in-basket overload by 34%, in 4 steps 4 ways to improve site-of-care transitions for sickle cell patients How VCU built an ‘inescapable' Adult Sickle Cell Medical Home to improve inpatient to outpatient transitions of care 4 keys to success in the New England Sickle Cell Institute's outpatient program for adult sickle cell patients A transcript of this episode as well as more information and resources can be found on RadioAdvisory.advisory.com.
On today's show we are looking at the anxiety of missing a deal. Real estate investors are deal junkies. Let's call it like it is. We're going to look at a real life example. We're going to talk about creating value with land. There are two main methods for creating land value. One is to start with raw land and carve it up and get it zoned and serviced for development. The other is to take land that has already been carved up into tiny parcels and put it back together so you can do something more substantial with it. Sellers are often of a mindset that they are the ones holding the cards. Their property is worth a gazillion dollars, especially if it has development potential. Some rich developer will come along and offer me so much more than the property is worth in its current condition to an owner occupant. In a dense urban environment land is both scarce and abundant. It's abundant in the sense that there are hundreds of properties for sale at any given time. Most of the land is not suitable for redevelopment in its current form.A case in point is a small land assembly that has already been designed for a 66 unit mid rise building. 66 units is a bit small from a property management standpoint. Ideally a building should have more than 100 units in order to optimize the economics of staffing the project.The proposed building is already compliant with the zoning requirements and can be built by right. There are constraints on the size of a building on this street because of utility capacity on the street. A larger building would require an upgrade to the water main which would add considerable cost and delays to the project. The main constraint is water volume for fire suppression. A larger building would require a larger water main pipe and possibly a booster pump if the pressure at the top of the building is not sufficient. So we know we are not going to get more density on that block regardless of the zoning. The original land assembly consisted of two properties and along the way different scenarios of three and four properties were considered and negotiated.In the end, while a larger project would have been possible, we opted for a smaller mid-sized project at only 66 units. This past week, two more properties came up for sale on the same street. Among those was a property that had previously been considered. It was being offered at 30% below the original asking price. This is where sellers often get confused. You see there are realtors out there who will pick the most expensive comparable sale in the area and recommend that as the asking price for the sale. It's as if there is a broad market for development land and the offers will start pouring in the second the land hits the market. But when you are offering a property that will ultimately form part of a land assembly the market for buyers shrinks dramatically. You have two neighbours, one on the left and one on the right. There are only two possible buyers for your property as a development site. ----------------**Real Estate Espresso Podcast:** Spotify: [The Real Estate Espresso Podcast](https://open.spotify.com/show/3GvtwRmTq4r3es8cbw8jW0?si=c75ea506a6694ef1) iTunes: [The Real Estate Espresso Podcast](https://podcasts.apple.com/ca/podcast/the-real-estate-espresso-podcast/id1340482613) Website: [www.victorjm.com](http://www.victorjm.com) LinkedIn: [Victor Menasce](http://www.linkedin.com/in/vmenasce) YouTube: [The Real Estate Espresso Podcast](http://www.youtube.com/@victorjmenasce6734) Facebook: [www.facebook.com/realestateespresso](http://www.facebook.com/realestateespresso) Email: [podcast@victorjm.com](mailto:podcast@victorjm.com) **Y Street Capital:** Website: [www.ystreetcapital.com](http://www.ystreetcapital.com) Facebook: [www.facebook.com/YStreetCapital](https://www.facebook.com/YStreetCapital) Instagram: [@ystreetcapital](http://www.instagram.com/ystreetcapital)
Ready for a crash course in marketing strategy? In today's episode, I'm talking with acupuncturist Michelle Grasek about her top marketing tips. Michelle is the creator behind the Acupuncture Marketing School and podcast, and she is diving into her strategies for overcoming marketing fears, getting new patients quickly, and so much more. Review full show notes and resources at mollycahill.com/podcastMentioned in this Episode:Acupuncture Marketing School - Get $200 off with code HOLISTICHUB: michellegrasek.com/acupuncture-marketing-schoolAcupuncture Marketing School Podcast: michellegrasek.com/blogMichelle Grasek Website: michellegrasek.comMichelle Grasek Instagram: instagram.com/michellegrasekHolistic Marketing Hub holisticmarketinghub.com/enrollFollow Molly on Instagram: instagram.com/mollyacahill
'Haemorrhoids is one of those embarrassing problems that a lot of people suffer from. There's a lot of taboos surrounding it, because people don't want to own up that they've got haemorrhoids. A lot of people listening or watching this probably have haemorrhoids, they're probably sitting on them right now. That video is not a sexy topic, but it got over 2 million views... that is a huge amount of people that I could see across 100 clinics, and still not get to that number.' In this week's episode, Dr Louise Newson is joined by Dr Karan Rajan, a doctor, health educator, and host of the Dr Karan Explores podcast. With millions of followers across his social media platforms, Dr Karan showcases the power of social media to ‘de-taboo the taboo', tackling topics including menopause, women's health, and bowel issues. He stresses the harm caused by shame and silence, reminding us that ‘taboo should not be associated with any disease or condition'. A passionate advocate for accessible, jargon-free medical education, Dr Karan believes that everyone deserves to feel confident in understanding and managing their own health. Together, he and Dr Louise challenge persistent myths, like the notion that testosterone is a male-only hormone – exploring how such misconceptions reinforce outdated ideas that negatively impact patient care. They also address how misinformation, stigma and a one size fits approach to medicine creates barriers to care, particularly in women's health such as menopause and endometriosis. This episode explores the evolving role of medical educators, and is a call for more open, informed conversations – because great medicine should never settle for ‘good enough'. Watch on YouTube We hope you love the new series! Share your thoughts with us on the feedback form here and if you enjoyed today's episode, don't forget to leave a 5-star rating on your podcast platform. Email dlnpodcast@borkowski.co.uk with suggestions for new guests! Disclaimer The information provided in this podcast is for informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition. The views expressed by guests are their own and do not necessarily reflect the views of Dr Louise Newson or the Newson Health Group. LET'S CONNECT Website: Dr Louise Newson Instagram: The Dr Louise Newson Podcast (@drlouisenewsonpodcast) • Instagram photos and videos LinkedIn: Louise Newson | LinkedIn Spotify: The Dr Louise Newson Podcast | Podcast on Spotify YouTube: Dr Louise Newson - YouTube CONNECT WITH DR KARAN Website: Dr Karan Rajan Instagram: Dr Karan Rajan (MRCS MBBS BSc) (@drkaranrajan) • Instagram photos and videos LinkedIn: Dr Karan Rajan | LinkedIn Spotify: Dr Karan Explores | Podcast on Spotify YouTube: Dr Karan - YouTube
Are you unknowingly giving power to your competitors before a patient ever walks through your door? In the digital world, perception is power… and if your online presence feels weak, outdated, or inconsistent, you're losing control of the narrative. In Episode 130 of Shorr Solutions: The Podcast, host Jay Shorr shows you how to reclaim authority at every step of the digital patient journey. From dominating search results to controlling the conversation through automation, lead capture, and smart design, this episode is your guide to turning passive browsers into loyal patients while positioning your practice as the obvious choice.Schedule your free consult with our expert, Jay Shorr, here. To sign up for our Conversion Cascade 2.0 online course, click here. Don't forget to enter code PODCAST at checkout for 20% OFF! Connect with us:Website: https://shorrsolutions.com/Instagram: https://www.instagram.com/shorrsolutionsFacebook: https://www.facebook.com/shorrsolutionsLinkedIn: https://www.linkedin.com/company/shorrsolutionsYouTube: https://www.youtube.com/user/TheBestMBS1/featured
In this episode of the Scope of Things, host Deborah Borfitz brings you the latest news on AI-recommended precision dosing, organoid drug testing aiding treatment selection for bowel cancer, an AI tool for stratifying lung cancer patients, using HIV drugs to treat Alzheimer's disease, and the potential value of magic mushrooms to remedy the mood symptoms of Parkinson's. Blythe Adamson, international head of outcomes research and evidence generation at Flatiron Health, also joins in to discuss groundbreaking work harmonizing patient-level real-world data across four countries to enable multinational oncology research. News Roundup CURATE.AI platform Article in Clinical Research News Study in npj Precision Oncology FORECAST-2 clinical trial News on the Walter and Eliza Hall Institute website AI tool for sorting cancer patients Study in Nature Communications HIV drugs for Alzheimer's protection Study in Alzheimer's & Dementia “Magic mushrooms” for Parkinson's disease Study in Neuropsychopharmacology Guest Blythe Adamson, Ph.D., international head of outcomes research and evidence generation at Flatiron Health Flatiron Health enabling multinational oncology researh – article in Bio-IT World Subscribe to the podcast on Apple Podcasts and leave a review to support the show. Join us at Scope Europe on October 14-15 in Barcelona - use code SOT10 for an additional 10% discount. GUEST BIO Blythe Adamson, PhD, MPH, Head of Outcomes Research and Evidence Generation, International at Flatiron Health & Founder of Infectious Economics Dr. Blythe Adamson is the head of international outcomes research and evidence generation at Flatiron Health. As a visionary senior leader at Flatiron Health, her team pioneered deep learning language models for extraction of clinical details from EHR documents, breaking the limits of what was possible for humans to do alone. Learning from the experience of millions of patients with cancer, they generate evidence of treatment effectiveness and value used by governments around the world. Dr. Adamson co-invented a patented clinical decision-support tool, enabled by machine learning, that is used by cancer clinics to benefit patients. She holds degrees in microbiology, epidemiology, and pharmaceutical economics with a focus on infectious disease prevention. Dr. Adamson has held roles at the Bill and Melinda Gates Foundation Institute for Disease Modeling, the NIAID HIV Vaccine Trials Network, and Flatiron Health. The Scope of Things podcast explores clinical research and its possibilities, promise, and pitfalls. Clinical Research News senior writer, Deborah Borfitz, welcomes guests who are visionaries closest to the topics, but who can still see past their piece of the puzzle. Focusing on game-changing trends and out-of-the-box operational approaches in the clinical research field, the Scope of Things podcast is your no-nonsense, insider's look at clinical research today.
Supplements for Cardiovascular Prevention Guest: Lisa M. Gilman, APRN, C.N.P. Host: Stephen L. Kopecky, M.D. Supplement use is a growing industry in which patients seek additional potential benefit of reducing disease burden and improving overall health. This presentation will be an overview of supplements used to address cardiovascular disease prevention Topics Discussed: Our patients will often inquire if there are any supplements that would help their heart health. How do you approach this topic? What supplements have been suggested to help improve cardiovascular health? Patients may ask, how do we know if we are purchasing a good supplement? Are there any other considerations to be thinking of to instruct our patients about supplements? Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices. LinkedIn: Mayo Clinic Cardiovascular Services Cardiovascular Education App: The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today! No CME credit offered for this episode. Podcast episode transcript found here.
Effect of Colchicine on Progression of Known Coronary Atherosclerosis in Patients With Stable Coronary Artery Disease Compared to Placebo: The Ekstrom Trial
Un séjour typique aux urgences du Québec a duré 5 heures et 23 minutes l’an dernier, révèle un nouveau rapport de l’IEDM. Entrevue avec Renaud Brossard, vice-président communications à l’Institut économique de Montréal (IEDM). Regardez aussi cette discussion en vidéo via https://www.qub.ca/videos ou en vous abonnant à QUB télé : https://www.tvaplus.ca/qub ou sur la chaîne YouTube QUB https://www.youtube.com/@qub_radio Pour de l'information concernant l'utilisation de vos données personnelles - https://omnystudio.com/policies/listener/fr
Pfingsten rückt an – samt Bierdosen-Österreichern und absurden Schlagzeilen: Trinkgeld wird zur Steuerfalle, die ÖGK spart bei Patient:innen, nicht bei Luxushotels. In der Nationalbank gab's Massagen statt Meetings, bei der Matura wird's bald wieder ernster, und wer korrekt parkt, zahlt trotzdem Strafe. Außerdem: Karl-Heinz Grasser tritt seine Haft an – mit Rückblick auf die Buwog-Affäre. Und die Champions League? Heuer sowas von wurscht.
In dieser Folge geht's um ein brandaktuelles Thema, denn seit dem 1. Juni 2025 sind die neuen Regelungen zum Mutterschutz bei Fehl- und Totgeburten in Kraft getreten. Darum spricht Mela mit Hörerin Angelika über ihre Erfahrungen als Sternenkind-Mama und die Herausforderungen, die sie im medizinischen System erlebt hat. Angelika teilt ihre Geschichte, die von der Diagnose bis zur Stillen Geburt ihrer Tochter reicht, und thematisiert die persönliche Tragödie im so unpersönlichen System, die viele Eltern in ähnlichen Situationen durchleben. Dabei ordnen die beiden die neuen Mutterschutz-Regelungen ein und erklären, warum diese nur ein kleiner Schritt in die richtige Richtung sind. Die beiden reflektieren über ihre eigenen Erfahrungen und die Notwendigkeit, dass medizinisches Personal nicht nur fachlich kompetent, sondern auch emotional einfühlsam sein sollte. Ganz wichtig auch für Assistenzärztin Mela: Es darf keine Glückssache sein, ob man als Patient:in mit Empathie behandelt wird oder nicht!
In this episode of PT Pintcast, we're calling out the BS behind long hospital waitlists and helping private practice PTs cut through the noise. If you've ever wondered how to build a patient base from scratch, market to people who are actually motivated, or show up on social media with value — this one's for you.You'll learn:How to create patient-focused content before you even treat your first clientThe psychology of pain, urgency, and price in physical therapyWhy direct access and same-day care is the true advantage for private practicesThe overlooked content that builds trust before the evaluation
We discuss capacity assessment, patient autonomy, safety, and documentation. Hosts: Anne Levine, MD Brian Gilberti, MD https://media.blubrry.com/coreem/content.blubrry.com/coreem/Capacity_Assessment.mp3 Download Leave a Comment Show Notes The Importance of Capacity Assessment Arises frequently in the ED, even when not formally recognized Carries both legal implications and ethical weight Failure to appropriately assess capacity can result in: Forced treatment without justification Missed opportunities to respect autonomy Increased risk of litigation and poor patient outcomes Defining Capacity Capacity is: Decision-specific: varies based on the medical choice at hand Time-specific: can fluctuate due to medical conditions, intoxication, delirium Distinct from competency, which is a legal determination Relies on a patient's ability to: Understand relevant information Appreciate the consequences Reason through options Communicate a clear choice Real-World ED Examples Intoxicated patient with head trauma refusing CT Unreliable neuro exam Potentially time-sensitive intracranial injury Elderly patient with sepsis refusing admission due to caregiving responsibilities Balancing autonomy vs. beneficence Patient with gangrenous diabetic foot refusing surgery Demonstrates logic and consistency despite high-risk decision The 4 Pillars of Capacity Assessment Understanding Can the patient explain: Their condition Recommended treatments Risks and benefits Alternatives and outcomes? Sample prompts:
Have you ever wondered what it's like to be both the healer and the one in need of healing? Meet Mallory Carlson, an acupuncturist of nearly 12 years who has simultaneously navigated her own 16-year journey with debilitating migraines and women's health issues. Mallory takes us deep into the raw reality of chronic pain, sharing how she's learned to read her body's signals and transform what once required days of recovery into hours. Her story illuminates the profound mental health challenges that come with chronic illness—from the isolation of canceled plans to the guilt of feeling like you're "too much"—and the powerful practice of self-compassion she's developed in response.The conversation turns particularly powerful when Mallory describes her experiences with medical gaslighting and the physical, almost shock-like reaction she had when finally finding a doctor who recognized her condition after 14 years of searching. "It was such a physical experience," she explains, "the act of being seen and finding someone who can take care of you."From this frustration emerged her platform, The Audacious Patient, born from righteous rage at healthcare inequities and dedicated to making complex medical information accessible. As Mallory shifts from hands-on patient care to education and advocacy, she's channeling her personal struggles into a mission that helps others avoid the years of confusion she endured.Whether you're managing chronic illness, supporting someone who is, or simply interested in healthcare advocacy, this episode offers practical wisdom, validation, and a reminder that sometimes our greatest challenges become our greatest gifts to others. As Mallory beautifully summarizes what it means to be part of a chronic illness community: "It's solidarity and just a quiet knowing... we just have to be there for each other."Send us a text Are you living with a chronic illness and want to make your voice heard? Rare Patient Voice connects patients and caregivers with research opportunities—so you can share your experiences and get paid for your time! Your insights help drive real change in healthcare.Let's Get Started - Rare Patient Voice Support the showSupport:https://rarepatientvoice.com/Myspooniesisters/https://www.etsy.com/shop/MySpoonieSistershttps://www.graceandable.com/?bg_ref=980:nzTyG6c9zK (Use code GAJen10)Website:https://myspooniesisters.com/ Discount Codes: GIANT Microbes | Gag Gifts, Teacher Gifts, Doctor Gifts, Gifts for Girlfriends and Boyfriends code SPOONIE20 for 20% off
In order to be patient we will have to wait and endure. See why and how as Brett Andrews shares.To watch the full devotional go to https://youtu.be/S3kWMsCUZgUShare your stories, prayer requests, or your response to this devotional in the comments below.If you would like to know more about New Life, who we are, what we believe, or when we meet, visit http://newlife.church. Or you can fill out a digital connection card at http://newlife.church/connect - we would love to get to know you better!
Listen to the truths about God and His patience. The enemy of our souls, Satan, would have us believe the lie that God is not kind enough, or patient enought or loving enough. Each of us needs to know, to believe that our heavenly Father will not toss us aside, or tell us we're just no good, or remind us of our failures. That is not His way - the truth will always be - He has all the patience in the world - and so much more.Daylight Meditations is a daily podcast from CFO North America. Please visit CFONorthAmerica.org to learn more about our retreats, and online courses. If you are encouraged by this time of meditation, please consider supporting us.Contributors: Elizabeth Ames, Michelle DeChant, and Adam Maddock
Dr. John Sweetenham shares highlights from Day 4 of the 2025 ASCO Annual Meeting, including new research on maintenance therapy in small cell lung cancer and a virtual reality psychosocial intervention for patients undergoing hematopoietic stem cell transplantation. Transcript Hello, I'm Dr. John Sweetenham, the host of the ASCO Daily News Podcast, with my takeaways on selected abstracts from Day 4 of the 2025 ASCO Annual Meeting. My disclosures are available in the transcript of this episode. Today's selection features reports of 3 randomized trials in very different clinical settings: maintenance therapy in extensive small cell lung cancer (SCLC), upfront surgery in advanced ovarian cancer, and a supportive care intervention for patients undergoing hematopoietic stem cell transplantation. The first of these studies, Abstract 8006, was presented by Dr. Luis Paz-Ares from the University Hospital [October 12] in Madrid, Spain, and reports the primary results of the IMforte trial. This was a phase 3 trial evaluating the combination of lurbinectedin and atezolizumab as first-line maintenance therapy in patients with extensive small cell lung cancer. Despite some improvements in the first-line treatment of extensive small cell lung cancer with the use of checkpoint inhibitors in combination with platinum-based chemotherapy, most of the patients experience early disease progression and long-term survival remains very limited. This provides a rationale for considering a maintenance intervention. Lurbinectedin is an alkylating agent and transcription inhibitor [that is] already approved in the United States for patients with relapsed/refractory metastatic SCLC following platinum-based chemotherapy. It has been shown to synergize with immune checkpoint inhibitors in pre-clinical studies and has also been evaluated in early-phase clinical trials. The IMforte trial is a global, randomized trial in which patients are initially treated with atezolizumab, and those patients who do not progress on induction therapy are then randomized to maintenance therapy with atezolizumab alone or atezolizumab with lurbinectedin. The primary endpoints of the study were progression-free and overall survival. Four hundred and eighty-three patients were randomized and at a median follow-up of 15 months, the median progression-free survival for patients who received the combination was 5.4 months and the median overall survival was 13.2 months. This compares with 2.1 and 10.6 months, respectively, in patients who received atezolizumab only. The lurbinectedin and atezolizumab combination was generally well-tolerated, with no new or unexpected safety signals. The benefit was consistent in magnitude across all the relevant patient subgroups. This is the first phase 3 study to show a progression-free and overall survivial improvement with first-line maintenance in extensive stage SCLC and the result is likely to be practice-changing, establishing a new standard of care in this tough-to-treat disease. Next up is LBA5500, presented by Dr. Sven Mahner from LMU University in Munich, Germany. This describes the results of the TRUST study, a randomized trial of upfront surgical therapy in advanced ovarian cancer. As background, total macroscopic tumor resection with maximal effort cytoreductive surgery is the cornerstone of treatment in patients with advanced ovarian cancer. The optimal timing of such surgery remains controversial, whether it's more beneficial as a primary cytoreductive surgery before chemotherapy or in the form of interval cytoreductive surgery after 3 cycles of neoadjuvant chemotherapy. Previous studies have addressed this issue, but results have been confounded by issues of patient and center selection. The TRUST study is a randomized, international, multicenter phase 3 trial that compares the outcomes of the timing of surgery in surgically fit patients with seemingly resectable FIGO stage IIIB/IVB ovarian, tubal, and peritoneal carcinoma. To ensure consistent and adequate surgical quality, participating centers in the trial were required to obtain accreditation and undergo an onsite quality assurance review. This included assessment of infrastructure, surgical proficiency, complete resection rates, and surgical volume. Seven hundred and ninety-seven patients with advanced ovarian cancer were randomized to undergo surgery prior to therapy with 6 cycles of carboplatin and paclitaxel along with bevacizumab and a PARP inhibitor, or to have the surgery between the third and fourth cycle of the same systemic therapy. Of the initial 797 patients, 688 comprised the intent-to-treat population, of whom 345 received primary cytoreductive surgery and 343 received neoadjuvant chemotherapy followed by interval cytoreductive surgery. The results show that patients undergoing primary surgery had significantly improved progression-free survival compared with those who had interval cytoreductive surgery (median progression-free survival was 22.1 months versus 19.7 months). No difference in overall survival was observed between the 2 arms of the study. This is the first study to show a benefit for primary cytoreductive surgery, although the progression-free survival improvement was not reflected in an overall survival difference. A subgroup analysis for patients who underwent complete cytoreduction suggests a progression-free survival and survival benefit, although it isn't clear to me that the study was powered for this endpoint. Nevertheless, these are very difficult studies to perform, and the investigators should be congratulated for this robustly conducted clinical trial. Today's final abstract is 1504, presented by Dr. Hermioni Amonoo from Harvard Medical School. The trial evaluated BMT-VR, a virtual reality psychosocial intervention for patients undergoing bone marrow transplantation. This randomized trial included adult patients undergoing autologous and allogeneic transplantation. The BMT-VR platform included, among others, modules addressing psychoeducation, coping, acceptance, and gratitude. BMT-VR patients were provided with VR headsets and completed all modules during their hospitalization. Patient-reported outcomes were then assessed at 2, 4, 12, and 24 weeks post-BMT. Use of the VR tool was tracked during hospitalization. Control patients received usual care during their hospital stay and were then assessed at the same intervals post-BMT. Eighty evaluable patients were randomized, 39 to BMT-VR and 41 to usual care. Completion rates for the BMT-VR modules were high [at] around 70-75%. Patients who received the BMT-VR intervention experienced significantly improved anxiety, quality of life, and coping at 4 weeks post-BMT. In the longer term, sustained benefits were seen at 24 weeks for some endpoints including quality of life, with some benefits, including for depression and PTSD symptoms, improving longitudinally over the study period. These data are preliminary and will need to be confirmed in larger multicenter studies, but this trial demonstrates the feasibility of using virtual interventions in our patients and also provides intriguing preliminary data that they may be effective. Thanks for listening to today's report and I hope you will join me again tomorrow to hear more top takeaways from the final day of ASCO25. If you value the insights that you hear on the ASCO Daily News Podcast, please remember to rate, review, and subscribe wherever you get your podcasts. Disclaimer: The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement. Find out more about today's speaker: Dr. John Sweetenham Follow ASCO on social media: @ASCO on Twitter @ASCO on Bluesky ASCO on Facebook ASCO on LinkedIn Disclosures: Dr. John Sweetenham: No relationships to disclose
Join AACE Past President and endocrinologist Dr. Susan Samson as she leads a compelling roundtable discussion highlighting the importance of the endocrine care team model. She is joined by nurse practitioner Dominique Uva, physician associate Sonia Bahroo, nurse scientist and diabetes educator Dr. Julia Blanchette, endocrine pharmacist Dr. Diana Isaacs, and nurse practitioner and clinical professor Dr. Chris Yedinak. Together, they explore how multidisciplinary care teams are essential to addressing the growing burden of endocrine diseases such as diabetes and thyroid disorders. Each expert shares how they collaborate across disciplines to improve access, provide patient support, and extend specialist care, especially in underserved communities. Tune in for practical insights, collaborative strategies, and a deeper look into how team-based care can elevate endocrine health outcomes.
Struggling to balance work and kidney disease? You're not alone — and this episode is your essential guide to thriving professionally and medically. We're joined by Dr. Jacquie, a leading expert in occupational health, to explore the critical intersection of employment, rights, and wellbeing for people living with chronic kidney disease (CKD).
https://x.com/ezzingaza/status/1924173298080063881I no longer go to the Indonesian hospital. What foolishness it is, to speak of hospitals in a place where life is no longer preserved but merely postponed. Once, I believed, oh, how bitterly I believed, that the presence of a doctor among the dying was a sacred thing, a last stand against the void. But here, where the void has taken residence in the very walls, what can sanctity do? The hospital is surrounded now. Not by men, not by soldiers even, but by machines. Drones, humming above like metallic locusts, devoid of soul or pity. They know neither suffering nor mercy, they are the purest expression of obedience without conscience. They circle the building like vultures circling a carcass not yet dead enough. Two days ago, the ceiling collapsed. A nurse had just spoken the word “hope.” Then came the blast, and the word hung in the air a moment too long before crumbling with the plaster. ICU monitors, those fragile gods of modern faith, shattered on the floor. One machine let out a long, wheezing beep as it died. It was the sound of resignation. I think I wept, but I cannot recall if it was with my eyes or only in my mind. And this morning, yes, this morning, as if dawn itself had become ashamed, a drone struck the intensive care unit. It came like a decision already made. There was no warning, no negotiation, no fate to plead with. Just fire. Patients ran. Doctors ran. The hallway became a river of chaos, but silent, terrifyingly silent. One man dragged his son by the shoulders, blood smearing behind them like a signature of some unseen pact. Another woman collapsed, not from injury but from the sheer weight of choosing which of her children to carry. Two patients were taken away in an ambulance, if that word still means anything. The rest had already passed into that cold stillness we now mistake for peace. We still work at the clinic, though I no longer know if it's from duty or habit, or some grotesque need to perform life while surrounded by death. We whisper. We disinfect. We bind wounds that will open again. The scalpel, once a tool of healing, now feels like an accomplice. At home, the walls speak in cracks. The roof sags under the pressure of memory. The air smells like dust and grief. My mother tapes the broken windows each day with the care of a priest dressing a corpse. My father rations rice with the reverence of a man offering communion. But outside, outside, it never stops. The bombing continues with the faithfulness of a priest at prayer. It does not pause. It does not tire. It beats like a heart possessed by something inhuman. And now, the streets. No, not streets, corridors of exile. Rows of tents like gravestones made of fabric. Children play in the ashes, unaware that they are survivors of a war not yet finished. The army says, Evacuate. To where? They do not say. Only: Leave. Disappear. Unbecome. Famine grows near. But even hunger, with its gnawing cruelty, is familiar. Hunger is intimate. It is ours. What is worse, what is unbearable, is the silence that follows the blast. The silence in which you call a name and no one answers. The silence where meaning once lived. This is not a war. It is annihilation dressed in the costume of procedure. It is a logic without soul, a godless arithmetic of bodies and coordinates. And still, still, some whisper that God watches. I do not know. Sometimes I think He has turned His face away, not out of indifference, but out of shame. But if you are reading this, if your eyes have reached these words like a boat reaching a shore you thought unreachable, then for the love of all things holy and damned: Do not look away. To look away is to become part of it. To forget is to bury us before we are dead. To remain silent is to drive the final nail.
In order to be patient we will have to wait and endure. See why and how as Brett Andrews shares.To watch the full devotional go to https://youtu.be/S3kWMsCUZgUShare your stories, prayer requests, or your response to this devotional in the comments below.If you would like to know more about New Life, who we are, what we believe, or when we meet, visit http://newlife.church. Or you can fill out a digital connection card at http://newlife.church/connect - we would love to get to know you better!
Canadian dental clinics can boost visibility, trust, and patient numbers with cost-effective, high-authority multichannel content. Ibex Media explains how coordinated articles, videos, and social coverage outperform isolated ads and help practices compete. Go to http://ibexmedia.ca for more information. Ibex Media City: Calabogie Address: 1036 Barryvale Road Website: http://ibexmedia.ca
那时候很单纯 I was very naive经历很多坎坷 I've been experiencing so many problems和过去不同 I could be very very different from the past years完全信任我 you can trust me with 100%
If you’ve ever felt unsure about how to bring past patients back into care—without feeling pushy or salesy—this episode is for you. In Part 2 of the Reactivation Blueprint, I’m breaking down the 8 principles behind a powerful recall and reactivation strategy. These aren’t just tactics—they’re the mindset, systems, and culture that make reactivations feel natural, ethical, and effective. You’ll learn: Why missed visits are quietly costing your practice thousands How to shift your team culture so follow-up feels like service—not selling The script I use at the ROF to set the foundation for future follow-up (and why it works so well) What the “White Coat Effect” teaches us about who should do the follow-up How to use categories to clean up your patient list and free up mental bandwidth The truth about “maybes” and why they drain more than just your books If you’re ready to follow up with confidence, reconnect with patients who already trust you, and grow without chasing cold leads—this episode will show you how. Hit play and let’s bring your best patients back—with care, not pressure.See omnystudio.com/listener for privacy information.
Dr. John Sweetenham shares highlights from Day 3 of the 2025 ASCO Annual Meeting, including new research for the treatment of advanced renal cell carcinoma and 2 studies on novel approaches in non-small cell lung cancer. Transcript Dr. John Sweetenham: Hello, I'm Dr. John Sweetenham, the host of the ASCO Daily News Podcast, with my takeaways on selected abstracts from Day 3 of the 2025 ASCO Annual Meeting. Today's selection features studies addressing the treatment of advanced renal cell carcinoma and 2 studies exploring novel approaches in non-small cell lung cancer. My disclosures are available in the transcript of this episode. The first abstract is number 4505. This study, led by Dr. Toni Choueiri of the Dana-Farber Cancer Institute, describes the final analysis of the CheckMate 214 trial, which compared the combination of nivolumab and ipilimumab with sunitinib for the first-line treatment of advanced renal cell carcinoma. The ipi-nivo combination is approved for the frontline treatment of intermediate and poor-risk advanced renal cell carcinoma based on the primary analysis of the CheckMate 214 trial, which demonstrated a higher response rate and longer overall survival compared with sunitinib. Today's presentation provided the final safety and efficacy results for the trial with long-term follow-up of more than 9 years. The intent-to-treat (ITT) population in this trial comprised 550 patients randomized to nivo and ipi versus 546 who received sunitinib. The final analysis showed sustained long-term benefit for the combination therapy. Patients given nivolumab plus ipi had a 29% reduction in the risk for death compared with sunitinib. For patients with intermediate or poor-risk disease, there was a 31% reduction in the risk of death. The probability of remaining in response through 8 years was more than doubled with nivolumab plus ipilimumab versus sunitinib in the ITT population at 48% versus 19%, and in the intermediate and poor-risk population at 50% versus 23%. The other important observation is that patients with favorable-risk disease appeared to have a 20% reduction in the risk for death at 9 years and more durable responses. This suggests a possible delayed benefit for ipi and nivo in this group since these differences were not seen in the earlier analysis. No new safety signals emerged with longer follow-up, and the results confirm the use of ipi and nivo as a standard front-line combination therapy in this disease. Since this combination has been in widespread use for some years, the results are not surprising although the subgroup analysis suggesting benefit in favorable-risk patients is likely to inform practice in the future. Today's second abstract is number is 8506, which was presented by Dr. Tony Mok from the Chinese University of Hong Kong, describing results from the phase 3 HERTHENA-Lung02 trial. This trial compared the antibody-drug conjugate patritumab deruxtecan with platinum-based chemotherapy in patients with EGFR-mutated advanced non-small cell lung cancer following a third-generation tyrosine kinase inhibitor (TKI). Patritumab deruxtecan, also known as HER3-DXd, comprises a fully human anti-HER3 IgG3 monoclonal antibody conjugated to a topoisomerase 1 inhibitor payload, and showed activity in a previous phase 2 trial in patients relapsing after EGFR TKI and chemotherapy. In this phase 3 study, this agent was compared with platinum-based chemotherapy in eligible patients with an EGFR-activating mutation who had previously received 1 or 2 EGFR TKIs, at least one of which was a third-generation drug, with relapse or progression after this therapy. Five hundred and eighty-six patients were enrolled, with progression-free survival as the primary endpoint. The primary analysis showed a 9-month progression-free survival of 29% for the experimental arm compared with 19% for platinum-based chemotherapy, for a hazard ratio of 0.77 and a P value of 0.011. With higher progression-free survival rates at 6 months and 12 months, HER3-DXd also had a better objective response rate (35.2% versus 25.3%) compared with platinum-based chemotherapy (PBC), and HER3-DXd also extended intracranial progression-free survival compared with PBC in patients with brain metastases, with a hazard ratio of 0.75. Grade 3 or more treatment-related adverse events occurred in 73% of patients treated with HER3-DXd and 57% of patients who received PBC. HER3-DXd had a higher rate of grade or more 3 thrombocytopenia, and drug-related interstitial lung disease occurred in 5% of patients in the HER3-DXd arm. The follow-up will need more time to mature since no overall survival data are currently available, but definitely an agent to watch with interest. Moving on to today's final abstract, 8500, was presented by Dr. Pasi Jänne from the Dana-Farber Cancer Institute, describing results from the phase 2 portion of the KRYSTAL-7 study. This study is exploring the use of a potent KRAS inhibitor, adagrasib, in combination with pembrolizumab in patients with advanced or metastatic KRASG12C- mutated non-small cell lung cancer. Adagrasib has already received accelerated approval in the U.S. for previously treated locally advanced or metastatic NSCLC with a KRASG12C mutation. A previous report from the KRYSTAL-7 study demonstrated encouraging activity in combination with pembrolizumab in the frontline setting for this patient group who also had more than 50% expression of PD-L1. The presentation today described efficacy and safety data for this drug combination across all PD-L1 expression levels. One hundred and forty-nine patients with a median age of 67 years were treated with the combination, 104 of whom had PD-L1 expression level results available, representing the so-called biomarker population in this trial. The overall response rate for the entire study population was 44%. In the biomarker population, the overall response rate ranged from 36% in those with less than 1% PD-L1 expression to 61% for those with more than 50% expression. For all patients, the median response duration was just over 26 months, and the median progression-free and overall survival rates were 11 and 18.3 months respectively. For the biomarker population, the median progression-free and overall survival were highest in those patients with more than 50% PD-L1. No new safety issues emerged from this analysis; the most frequent toxicities were nausea, diarrhea, and increases in transaminases. Immune-related toxicities included pneumonitis, hypothyroidism, and hepatitis. These are important results and the results of the phase 3 portion of KRYSTAL-7, which compares first-line therapy with adagrasib plus pembro versus pembro alone in the KRASG12C mutated/PD-L1 more than 50% group, will be informative. For those patients with lower levels of PD-L1 expression, the authors suggest that the treatment escalation may be beneficial, possibly including the addition of chemotherapy. That concludes today's report. Thanks for listening and I hope you will join me again tomorrow to hear more top takeaways from ASCO25. If you value the insights that you hear on the ASCO Daily News Podcast, please remember to rate, review, and subscribe wherever you get your podcasts. Disclaimer: The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement. Find out more about today's speaker: Dr. John Sweetenham Follow ASCO on social media: @ASCO on Twitter @ASCO on Bluesky ASCO on Facebook ASCO on LinkedIn Disclosures: Dr. John Sweetenham: No relationships to disclose
Doris Zallen, PhD, is Professor Emerita of Science Studies and Humanities at Virginia Tech. Her research explores personal, family, and societal issues arising from advances in genetic testing and gene therapy. Zallen is the author of two books about genetic testing and is developing an online tool to help people make informed choices about testing. Zallen […] The post Genetic Testing; Conversation with a Researcher and Patient Advocate (HLOL #260) appeared first on Health Literacy Out Loud Podcast.
This episode of VHHA's Patients Come First podcast features Dr. Jonathan Hemler, a pediatric allergist with UVA Health Children's, who joins us to discuss his work, the topic of allergies, new advancements in UVA's pediatric food allergy treatment program, and more. Send questions, comments, feedback, or guest suggestions to pcfpodcast@vhha.com or contact on X (Twitter) or Instagram using the #PatientsComeFirst hashtag.
This meditation draws upon the timeless wisdom of Seneca the Younger, guiding you to cultivate patience through the Stoic principles of acceptance, discernment, and inner strength. You will explore the profound difference between what you can control and what lies beyond your influence, learning to meet life's inevitable challenges with a calm and unconquerable mind. This practice is an invitation to transform impatience into resilient tranquility, anchoring your peace in the only place it can truly be found: within yourself. THIS WEEK'S THEME: "The Patient Heart: Cultivating Inner Stillness" Welcome to "The Patient Heart: Cultivating Inner Stillness," a 7-part meditation series designed to help you rediscover the profound power and peace found in patience. In a world that often demands instant gratification, true tranquility lies in our ability to wait, to observe, and to trust in the natural unfolding of life. Drawing upon the timeless wisdom of ancient traditions, this series will guide you to cultivate patience not as passive waiting, but as an active, compassionate engagement with the present moment. Each episode offers a unique lens to understand and embody this vital virtue, fostering inner resilience and a deeper connection to the rhythm of existence. YOUR MEDITATION JOURNEY DURING THIS WEEK'S SERIES This is episode 7 of a 7-day meditation series titled, "The Patient Heart: Cultivating Inner Stillness" episodes 3311-3316. Day 1: Patience Visualization Day 2: Patience Affirmation: "I unfold with patience, presence, and peace." Day 3: Patience Breathing Visualization Day 4: Lotus Mudra for Patience Day 5: Fourth Chakra focus for Patience Day 6: Patience flow meditation combining the week's techniques. Day 7: Weekly review meditation and closure. WEEKLY CHALLENGE: The Pause Pivot Challenge THE PAUSE (Awareness): When you feel that familiar tug of impatience (the urge to rush, frustration, annoyance, a sigh, tapping your foot, etc.), immediately internally say to yourself: "Aha! A Patience Opportunity!" Take one deep, intentional breath. Notice the sensations in your body and mind without judgment. This is your "Pause." THE PIVOT (Choice): After that single breath, consciously choose a patient response, even if it's small. This isn't about solving the problem instantly, but shifting your internal state. SHARE YOUR MEDITATION JOURNEY WITH YOUR FELLOW MEDITATORS Let's connect and inspire each other! Please share a little about how meditation has helped you by reaching out to me at Mary@SipandOm.com or better yet -- direct message me at https://www.instagram.com/sip.and.om. We'd love to hear about your meditation ritual! SUBSCRIBE, LEAVE A REVIEW + TAKE OUR SURVEY SUBSCRIBE so you don't miss a single episode. Consistency is the KEY to a successful meditation ritual. SHARE the podcast with someone who could use a little extra support. I'd be honored if you left me a podcast review. If you do, please email me at Mary@sipandom.com and let me know a little about yourself and how meditation has helped you. I'd love to share your journey to inspire fellow meditators on the podcast! SURVEY: Help us get to know more about how best to serve you by taking our demographics survey: https://survey.libsyn.com/thedailymeditationpodcast FOR DAILY EXTRA SUPPORT OUTSIDE THE PODCAST Each day's meditation techniques posted at: sip.and.om Instagram https://www.instagram.com/sip.and.om/ sip and om Facebook https://www.facebook.com/SipandOm/ A DIFFERENT MEDITATION TECHNIQUE EVERY DAY FOCUSED ON A WEEKLY THEME: Get ready for an exciting journey with a new meditation technique daily, perfectly tailored to the week's theme! Infuse these powerful practices into the most stressful moments of your day to master difficult emotions. These dynamic techniques will help you tame the "monkey mind," keeping your thoughts from interrupting your meditation and bringing peace and focus to your life. FREE TOOLS: For free meditation tools to help you meditate please head over to my website at www.SipandOm.com, and there you'll find free resources to help you on your Meditation Journey. Enjoy access to more than 3,000 guided meditations without ads on the Sip and Om app. Try it for 7 days of free access to the full app! Listen on iTunes for 1-Week Free! https://itunes.apple.com/us/app/sip-and-om/id1216664612?platform=iphone&preserveScrollPosition=true#platform/iphone 1-week Free Access to the Android app! https://play.google.com/store/apps/details?id=com.sipandom.sipandom ***All meditations are Mary Meckley's original copyrighted content unless otherwise stated, and may not be shared without her written permission. RESOURCES Music composed by Christopher Lloyd Clark licensed by RoyaltyFreeMusic.com, and also by musician Greg Keller. I'D LOVE TO HEAR FROM YOU I'd love your feedback! Please let me know how you're enjoying the meditations by leaving me a review on iTunes. **All of the information shared on this podcast is for your enjoyment only. Please don't consider the meditation techniques, herbal tea information, or other information shared by Mary Meckley or any of her guests as a replacement for any medical or psychological treatment. That being said, please enjoy any peace, energy, or clarity you may experience as you meditate. SHARE YOUR MEDITATION JOURNEY WITH YOUR FELLOW MEDITATORS Let's connect and inspire each other! Please share a little about how meditation has helped you by reaching out to me at Mary@SipandOm.com or better yet -- direct message me at https://www.instagram.com/sip.and.om. We'd love to hear about your meditation ritual! SUBSCRIBE, LEAVE A REVIEW + TAKE OUR SURVEY SUBSCRIBE so you don't miss a single episode. Consistency is the KEY to a successful meditation ritual. SHARE the podcast with someone who could use a little extra support. I'd be honored if you left me a podcast review. If you do, please email me at Mary@sipandom.com and let me know a little about yourself and how meditation has helped you. I'd love to share your journey to inspire fellow meditators on the podcast! SURVEY: Help us get to know more about how best to serve you by taking our demographics survey: https://survey.libsyn.com/thedailymeditationpodcast FOR DAILY EXTRA SUPPORT OUTSIDE THE PODCAST Each day's meditation techniques posted at: sip.and.om Instagram https://www.instagram.com/sip.and.om/ sip and om Facebook https://www.facebook.com/SipandOm/ A DIFFERENT MEDITATION TECHNIQUE EVERY DAY FOCUSED ON A WEEKLY THEME: Get ready for an exciting journey with a new meditation technique daily, perfectly tailored to the week's theme! Infuse these powerful practices into the most stressful moments of your day to master difficult emotions. These dynamic techniques will help you tame the "monkey mind," keeping your thoughts from interrupting your meditation and bringing peace and focus to your life. FREE TOOLS: For free meditation tools to help you meditate please head over to my website at www.SipandOm.com, and there you'll find free resources to help you on your Meditation Journey. Enjoy access to more than 3,000 guided meditations without ads on the Sip and Om app. Try it for 7 days of free access to the full app! Listen on iTunes for 1-Week Free! https://itunes.apple.com/us/app/sip-and-om/id1216664612?platform=iphone&preserveScrollPosition=true#platform/iphone 1-week Free Access to the Android app! https://play.google.com/store/apps/details?id=com.sipandom.sipandom ***All meditations are Mary Meckley's original copyrighted content unless otherwise stated, and may not be shared without her written permission. RESOURCES Music composed by Christopher Lloyd Clark licensed by RoyaltyFreeMusic.com, and also by musician Greg Keller. I'D LOVE TO HEAR FROM YOU I'd love your feedback! Please let me know how you're enjoying the meditations by leaving me a review on iTunes. **All of the information shared on this podcast is for your enjoyment only. Please don't consider the meditation techniques, herbal tea information, or other information shared by Mary Meckley or any of her guests as a replacement for any medical or psychological treatment. That being said, please enjoy any peace, energy, or clarity you may experience as you meditate.
In this powerful episode of the Tick Boot Camp Podcast, we sit down with Dr. Myriah Hinchey, a Lyme-literate naturopathic physician whose personal battle with Lyme disease, Babesia, and Bartonella shaped her pioneering approach to treatment. Dr. Hinchey is the founder and medical director of Tao Center for Vitality, Longevity & Optimal Health, creator of LymeCore Botanicals, and founder of LymeBytes, a global educational platform for Lyme disease. Dr. Hinchey shares how her journey from misdiagnosed childhood infections to a transformative diagnosis in her mid-30s inspired a career of advocacy and innovation in integrative Lyme treatment. Discover why she believes most chronic Lyme sufferers can heal — and how focusing on terrain, immune modulation, gut health, and targeted herbal antimicrobials makes recovery possible.
This episode recorded live at the Becker's Hospital Review 15th Annual Meeting features Quanna Batiste, Vice President, Patient Care Services and Chief Nursing Officer at Touro Infirmary, LCMC Health. Quanna shares insights on optimizing nursing structures, leading with transparency, and embracing innovations like virtual nursing and AI to drive clinical efficiency and future-ready care.
Dr. John Sweetenham shares highlights from Day 2 of the 2025 ASCO Annual Meeting, including new data on the treatment of ER+/HER2-negative breast cancer and potentially practice-changing results for patients with cutaneous squamous cell carcinoma at high risk of recurrence. Transcript Dr. John Sweetenham: Hello, I'm Dr. John Sweetenham, your host of the ASCO Daily News Podcast, welcoming you to our special coverage of the 2025 ASCO Annual Meeting. Today, I'll be bringing you my takeaways on selected abstracts from Day 2 of the Meeting. My disclosures are available in the transcript of this episode. Today's selection features important, new data on the treatment of ER-positive, HER2-negative breast cancer, the use of tumor treating fields in combination with chemotherapy for locally advanced pancreatic cancer, and potentially practice-changing results for patients with cutaneous squamous cell carcinoma at high-risk of recurrence. Our first selected abstract is LBA1000. This important phase 3 study was presented by Dr. Erika Hamilton from the Sarah Cannon Research Institute in Nashville and evaluated the use of a novel agent, vepdegestrant, in patients with ER-positive/HER2-negative breast cancer, which had progressed after first-line endocrine therapy. Vepdegestrant is a selective oral PROTAC estrogen receptor degrader, which targets wild-type and mutant estrogen receptor through a novel mechanism of action which directly harnesses the ubiquitin-proteasome system to degrade ER. It has potential advantages over fulvestrant, a selective ER degrader which has to be administered intramuscularly and has limited benefit in patients who progress after endocrine therapy plus a CDK4/6 inhibitor. Building on the encouraging results from the initial phase 1/2 study of vepdegestrant, Dr. Hamilton reported results from the VERITAC-2 global phase 3 trial, comparing this agent with fulvestrant. The patients in the study had already received treatment with hormone therapy and a CDK inhibitor and were randomly assigned to receive treatment with either vepdegestrant (313 patients) or fulvestrant (311 patients). The vepdegestrant was taken orally each day, while the fulvestrant was given intramuscularly on days 1 and 15 of the first cycle of treatment and day 1 of each subsequent treatment cycle. Patients were stratified by the presence of wild-type ER or ESR1 mutation. A total of 43.3% of patients had ESR1 mutations; 136 of those were in the vepdegestrant group and 134 in the fulvestrant group. For patients with ESR1 mutations, vepdegestrant significantly increased progression-free survival compared with fulvestrant. For patients who received vepdegestrant, the median PFS was 5 months versus 2.1 months for those who received fulvestrant. The clinical benefit rate was 42.1% in the vepdegestrant group vs. 20.2% in the fulvestrant group. The overall response rate was 18.6% in the vepdegestrant group compared with only 4% in the fulvestrant group. The PFS and response benefits of vepdegestrant were largely restricted to the population with ESR1 mutations. Overall survival data are currently immature. The safety profile was favorable, with fewer than 5% of patients having dose reductions or discontinuation due to toxicity. The most frequent toxicities were fatigue, nausea, and elevated transaminases. The authors concluded that oral vepdegestrant demonstrates statistically significant and clinically meaningful improvement in progression-free survival compared with fulvestrant in this group of patients with ESR1-mutated ER+/HER2- advanced breast cancer who have progressed after endocrine therapy and a CDK inhibitor. Patients with recurrent disease in this context are now routinely tested for ESR1 mutations, and this agent is for sure a potential treatment option for them. The next study on today's episode, LBA4005, reports on the use of tumor treatment fields for patients with locally advanced pancreatic cancer. Tumor treatment fields are electric fields which disrupt cell division and may also induce an enhanced immune response, using a non-invasive portable device attached to the skin, and are already approved for the treatment of some cancers, including GBM and non-small cell lung cancer. A previous phase 2 trial, PANOVA-2, confirmed the feasibility and safety of using this approach in combination with gemcitabine plus or minus nabpaclitaxel in pancreatic cancer. In today's presentation, Dr. Vincent Picozzi from the Virginia Mason Medical Center in Seattle presented the results of the PANOVA-3 trial, a phase 3 study comparing gemcitabine and nabpaclitaxel with the same chemotherapy plus tumor treatment fields in patients with locally advanced pancreatic adenocarcinoma. Five hundred and seventy-one eligible patients were enrolled in the study with a total of 405 (198 in the treatment field group and 207 in the standard arm) comprising the modified intent- to-treat population. The duration of chemotherapy treatment was comparable in both study arms, and patients receiving treatment fields had a median exposure of almost 27 weeks. Statistically significant improvements were observed for several study endpoints, including overall survival (a median of 16.2 versus 14.2 months), distant PFS (at 13.9 versus 11.5 months) and pain-free survival (at 15.2 versus 9.1 months), all in favor of the treatment fields arm. Although quality of life data were not reported in detail, the authors noted a significant improvement in global health status in the treatment fields arm. Safety data showed a higher level of skin adverse events in the treatment fields arm but were otherwise as expected for the GnP combination. These are quite remarkable results which add to the growing evidence base for tumor treatment fields and are particularly compelling in this patient group given the substantial improvement in pain-free survival. It will be especially interesting to see the mature analysis of the quality-of-life endpoints in a subsequent report. The final selection today is Abstract 6001, which describes the C-POST trial, a phase 3 trial of adjuvant cemiplimab versus placebo in patients with high-risk cutaneous squamous cell carcinoma of the skin. This study was presented by Dr. Danny Rischin from the Peter MacCallum Cancer Centre in Melbourne, Australia. Although surgical resection with or without adjuvant radiation is curative in 90% of patients with cutaneous squamous cell carcinoma, high-risk features, including nodal disease, skin and subcutaneous metastases, perineural invasion and bone involvement, predict for an inferior prognosis. Cemiplimab, a PD-1 targeting antibody is standard therapy for patients with locally advanced or metastatic disease who are not candidates for curative surgical resection or radiation therapy, with an overall response rate of almost 50%. The C-POST study evaluated the use of cemiplimab as adjuvant therapy following surgery and radiation in high-risk patients, compared with placebo. Treatment was administered at 3-week intervals for 12 weeks, and then 6-week intervals for a further 36 weeks, with a primary endpoint of disease-free survival. Four hundred and fifteen patients were randomized in the study, 209 to cemiplimab and 206 to placebo. With median follow-up at 24 months, Dr. Rischin reported a highly significant improvement in disease-free survival for the cemiplimab arm, 49.4 months for placebo versus not reached for cemiplimab, with improvements also observed in the rates of locoregional recurrence and distant recurrence at 80% and 60% reductions, respectively. No new safety signals were observed. This study is potentially practice-changing and provides strong evidence that cemiplimab should be considered the new standard of care in this clinical context. Thanks for listening today and join me again tomorrow to hear more top takeaways from ASCO25. If you value the insights that you hear on the ASCO Daily News Podcast, please remember to rate, review, and subscribe wherever you get your podcasts. Disclaimer: The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement. Find out more about today's speaker: Dr. John Sweetenham Follow ASCO on social media: @ASCO on Twitter @ASCO on Bluesky ASCO on Facebook ASCO on LinkedIn Disclosures: Dr. John Sweetenham: No relationships to disclose
Send us a textThe mobile prosthetic clinic model is gaining traction as Hanger acquires Colorado-based Agile Orthopedics, potentially changing how prosthetic care is delivered nationwide. Raise3D's new RMS-220 SLS printer enters the market with open material capabilities, challenging the economics of small-scale prosthetic production.• Mobile clinics solve transportation challenges for patients with mobility limitations• Bringing care directly to patients is especially valuable in rural areas with weather challenges• Centralized fabrication pairs perfectly with mobile clinical services• Hanger could dramatically expand market reach by adding mobile clinics to existing locations• Open-material 3D printers may help control costs when material prices increase but reimbursement doesn't• Entry-level SLS systems face challenges with powder handling and economic viability• Lattice structures should be used thoughtfully based on function, not just aesthetics• Using others' designs without permission demonstrates disrespect for intellectual propertyJoin us next time as we continue exploring innovations in prosthetics and orthotics. Remember to subscribe to the podcast and share with colleagues who might benefit from these discussions.Special thanks to Advanced 3D for sponsoring this episode.Support the show
Something is shifting—and fast.After decades of preaching root-cause healing, functional medicine, and whole-body wellness, Dr. Bill Janeshak is finally hearing what he's waited years to hear… from the patients themselves.In this powerful solo episode, Dr. J pulls back the curtain on a quiet revolution now reaching critical mass. Patients are speaking up—loud and clear:
Episode 2651: Vinnie Tortorich talks with Dr. Amy Gutman about her TED Talk, how "kind" lies are the hurting kind, her journey from being vegan, and more. https://vinnietortorich.com/2025/05/the-hurting-kind-dr-amy-gutman-episode-2651 PLEASE SUPPORT OUR SPONSORS YOU CAN WATCH ALL THE PODCAST EPISODES ON YOUTUBE - The Hurting Kind Dr. Amy Gutman is an emergency room physician. (9:30) Vinnie shares a recent episode of back pain. (10:00) Dr. Amy did a TED talk on pain perception. (16:00) They discuss Vinnie's back pain further, leading to insurance issues. She shares the subject of her TED Talk “Patients Are Hurt by Kind Lies.” (36:00) Patient satisfaction is based on the idea that “happy patients have better outcomes,” but this is not always the case. (44:30) Physicians hesitate to counsel their patients because of the way funding works for hospitals. (45:15) It's a sick-care problem. (47:00) There is fear and pushback on the ideas around shaming. (50:00) Many doctors' offices avoid weighing patients because it supposedly “shames” a person. However, many treatments require knowing the patient's weight for proper prescription dosage or treatment. Doctors' hands are often tied because of the limited time they are allowed to spend with a patient. Dr. Amy had been vegan for 37 years and was beginning to get very ill, and she describes what issues she was battling. (57:00) She came across Vinnie's documentaries and started to make changes in her diet. She also discovered Dr. Tro Kalayjian and Dr. Terry Wahls. She felt better within days. They discuss the politicization of food. (1:10:00) Amy's TED Talk was labeled with a triggering warning because she talks about obesity and drug abuse. Her goal is to open up the conversation between doctors and their patients. (1:19:00) You can find Dr. Amy Gutman on social media at: On X: @ToughLoveMD On Instagram: On LinkedIn: More News If you are interested in the NSNG® VIP group, closed for registration, but you can get on the wait list - Don't forget to check out Serena Scott Thomas on Days of Our Lives on the Peacock channel. “Dirty Keto” is available on Amazon! You can purchase or rent it . Make sure you watch, rate, and review it! Eat Happy Italian, Anna's next cookbook, is available! You can go to You can order it from . Anna's recipes are in her cookbooks, website, and Substack–they will spice up your day! Don't forget you can invest in Anna's Eat Happy Kitchen through StartEngine. Details are at Eat Happy Kitchen. There's a new NSNG® Foods promo code you can use! The promo code ONLY works on the NSNG® Foods website, NOT on Amazon. https://nsngfoods.com/ PURCHASE DIRTY KETO (2024) The documentary launched in August 2024! Order it TODAY! This is Vinnie's fourth documentary in just over five years. Visit my new Documentaries HQ to find my films everywhere: Then, please share my fact-based, health-focused documentary series with your friends and family. Additionally, the more views, the better it ranks, so please watch it again with a new friend! REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! PURCHASE BEYOND IMPOSSIBLE (2022) Visit my new Documentaries HQ to find my films everywhere: REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! FAT: A DOCUMENTARY 2 (2021) Visit my new Documentaries HQ to find my films everywhere: FAT: A DOCUMENTARY (2019) Visit my new Documentaries HQ to find my films everywhere:
Most big goals in life require sustained effort and long-term patience. Be guided as you connect with your deeper aspirations, understanding that growth and mastery take time. Ancient Wisdom Weave: Inspired by Confucian ethics on persistent self-cultivation and the enduring commitment to virtue and lifelong learning. THIS WEEK'S THEME: "The Patient Heart: Cultivating Inner Stillness" Welcome to "The Patient Heart: Cultivating Inner Stillness," a 7-part meditation series designed to help you rediscover the profound power and peace found in patience. In a world that often demands instant gratification, true tranquility lies in our ability to wait, to observe, and to trust in the natural unfolding of life. Drawing upon the timeless wisdom of ancient traditions, this series will guide you to cultivate patience not as passive waiting, but as an active, compassionate engagement with the present moment. Each episode offers a unique lens to understand and embody this vital virtue, fostering inner resilience and a deeper connection to the rhythm of existence. YOUR MEDITATION JOURNEY DURING THIS WEEK'S SERIES This is episode 6 of a 7-day meditation series titled, "The Patient Heart: Cultivating Inner Stillness" episodes 3311-3316. Day 1: Patience Visualization Day 2: Patience Affirmation: "I unfold with patience, presence, and peace." Day 3: Patience Breathing Visualization Day 4: Lotus Mudra for Patience Day 5: Fourth Chakra focus for Patience Day 6: Patience flow meditation combining the week's techniques. Day 7: Weekly review meditation and closure. WEEKLY CHALLENGE: The Pause Pivot Challenge THE PAUSE (Awareness): When you feel that familiar tug of impatience (the urge to rush, frustration, annoyance, a sigh, tapping your foot, etc.), immediately internally say to yourself: "Aha! A Patience Opportunity!" Take one deep, intentional breath. Notice the sensations in your body and mind without judgment. This is your "Pause." THE PIVOT (Choice): After that single breath, consciously choose a patient response, even if it's small. This isn't about solving the problem instantly, but shifting your internal state. SHARE YOUR MEDITATION JOURNEY WITH YOUR FELLOW MEDITATORS Let's connect and inspire each other! Please share a little about how meditation has helped you by reaching out to me at Mary@SipandOm.com or better yet -- direct message me at https://www.instagram.com/sip.and.om. We'd love to hear about your meditation ritual! SUBSCRIBE, LEAVE A REVIEW + TAKE OUR SURVEY SUBSCRIBE so you don't miss a single episode. Consistency is the KEY to a successful meditation ritual. SHARE the podcast with someone who could use a little extra support. I'd be honored if you left me a podcast review. If you do, please email me at Mary@sipandom.com and let me know a little about yourself and how meditation has helped you. I'd love to share your journey to inspire fellow meditators on the podcast! SURVEY: Help us get to know more about how best to serve you by taking our demographics survey: https://survey.libsyn.com/thedailymeditationpodcast FOR DAILY EXTRA SUPPORT OUTSIDE THE PODCAST Each day's meditation techniques posted at: sip.and.om Instagram https://www.instagram.com/sip.and.om/ sip and om Facebook https://www.facebook.com/SipandOm/ A DIFFERENT MEDITATION TECHNIQUE EVERY DAY FOCUSED ON A WEEKLY THEME: Get ready for an exciting journey with a new meditation technique daily, perfectly tailored to the week's theme! Infuse these powerful practices into the most stressful moments of your day to master difficult emotions. These dynamic techniques will help you tame the "monkey mind," keeping your thoughts from interrupting your meditation and bringing peace and focus to your life. FREE TOOLS: For free meditation tools to help you meditate please head over to my website at www.SipandOm.com, and there you'll find free resources to help you on your Meditation Journey. Enjoy access to more than 3,000 guided meditations without ads on the Sip and Om app. Try it for 7 days of free access to the full app! Listen on iTunes for 1-Week Free! https://itunes.apple.com/us/app/sip-and-om/id1216664612?platform=iphone&preserveScrollPosition=true#platform/iphone 1-week Free Access to the Android app! https://play.google.com/store/apps/details?id=com.sipandom.sipandom ***All meditations are Mary Meckley's original copyrighted content unless otherwise stated, and may not be shared without her written permission. RESOURCES Music composed by Christopher Lloyd Clark licensed by RoyaltyFreeMusic.com, and also by musician Greg Keller. I'D LOVE TO HEAR FROM YOU I'd love your feedback! Please let me know how you're enjoying the meditations by leaving me a review on iTunes. **All of the information shared on this podcast is for your enjoyment only. Please don't consider the meditation techniques, herbal tea information, or other information shared by Mary Meckley or any of her guests as a replacement for any medical or psychological treatment. That being said, please enjoy any peace, energy, or clarity you may experience as you meditate. SHARE YOUR MEDITATION JOURNEY WITH YOUR FELLOW MEDITATORS Let's connect and inspire each other! Please share a little about how meditation has helped you by reaching out to me at Mary@SipandOm.com or better yet -- direct message me at https://www.instagram.com/sip.and.om. We'd love to hear about your meditation ritual! SUBSCRIBE, LEAVE A REVIEW + TAKE OUR SURVEY SUBSCRIBE so you don't miss a single episode. Consistency is the KEY to a successful meditation ritual. SHARE the podcast with someone who could use a little extra support. I'd be honored if you left me a podcast review. If you do, please email me at Mary@sipandom.com and let me know a little about yourself and how meditation has helped you. I'd love to share your journey to inspire fellow meditators on the podcast! SURVEY: Help us get to know more about how best to serve you by taking our demographics survey: https://survey.libsyn.com/thedailymeditationpodcast FOR DAILY EXTRA SUPPORT OUTSIDE THE PODCAST Each day's meditation techniques posted at: sip.and.om Instagram https://www.instagram.com/sip.and.om/ sip and om Facebook https://www.facebook.com/SipandOm/ A DIFFERENT MEDITATION TECHNIQUE EVERY DAY FOCUSED ON A WEEKLY THEME: Get ready for an exciting journey with a new meditation technique daily, perfectly tailored to the week's theme! Infuse these powerful practices into the most stressful moments of your day to master difficult emotions. These dynamic techniques will help you tame the "monkey mind," keeping your thoughts from interrupting your meditation and bringing peace and focus to your life. FREE TOOLS: For free meditation tools to help you meditate please head over to my website at www.SipandOm.com, and there you'll find free resources to help you on your Meditation Journey. Enjoy access to more than 3,000 guided meditations without ads on the Sip and Om app. Try it for 7 days of free access to the full app! Listen on iTunes for 1-Week Free! https://itunes.apple.com/us/app/sip-and-om/id1216664612?platform=iphone&preserveScrollPosition=true#platform/iphone 1-week Free Access to the Android app! https://play.google.com/store/apps/details?id=com.sipandom.sipandom ***All meditations are Mary Meckley's original copyrighted content unless otherwise stated, and may not be shared without her written permission. RESOURCES Music composed by Christopher Lloyd Clark licensed by RoyaltyFreeMusic.com, and also by musician Greg Keller. I'D LOVE TO HEAR FROM YOU I'd love your feedback! Please let me know how you're enjoying the meditations by leaving me a review on iTunes. **All of the information shared on this podcast is for your enjoyment only. Please don't consider the meditation techniques, herbal tea information, or other information shared by Mary Meckley or any of her guests as a replacement for any medical or psychological treatment. That being said, please enjoy any peace, energy, or clarity you may experience as you meditate.
Sponsored by Invivyd, Inc.Nobody wants to hear about COVID-19 anymore. Especially not cancer patients. But if you've got a suppressed immune system thanks to chemo, radiation, stem cell transplants—or any of the other alphabet soup in your chart—then no, it's not over. It never was. While everyone else is getting sweaty at music festivals, you're still dodging a virus that could knock you flat.In this episode, Matthew Zachary and Matt Toresco say the quiet part out loud: many immunocompromised people may not even know they have options beyond vaccines. Why? Because the system doesn't bother to tell them. So we're doing it instead. We teamed up with Invivyd to help get the word out about tools other than vaccines that can help prevent COVID-19. We break down the why, the what, and the WTF of COVID-19 risk for cancer patients and why every oncologist should be talking about this.No fear-mongering. No sugarcoating. Just two guys with mics who've been through it and want to make sure you don't get blindsided. It's fast, funny, and furious—with actual facts. You've got more power than you think. Time to use it.RELATED LINKSExpand Their OptionsInvivydMatt Toresco on LinkedInOut of Patients podcastFEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship inquiries, email podcast@matthewzachary.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
As the prairie fires force Manitobans from their home, the head of the province's nurses union tells us how her members are caring for others, when their own homes and loved ones are at risk.A Swiss village manages to evacuate, but not to save their historic community, as a massive glacier collapses and buries their homes under millions of tons of rock and ice.We hear from with an Alaskan man who got trapped under an enormous boulder while out hiking, and his wife, who helped rescue him – just in the nick of time.A new study suggests horses use a wide range of facial expressions to communicate, not just with their human keepers, but with one another.Taylor Swift announces that after all of the drama, and all of the Taylor's Versions, she is now the proud owner of her entire catalogue of music.The Hollywood hit "Sinners" is a Jim-Crow-era horror set in Clarksdale, Mississippi, where locals were excited to see it but couldn't because the city doesn't have a movie theatre. We hear from one of the people who pulled off a special showing, with some special guests.As It Happens, the Friday Edition. Radio that always screens with excitement.
In this thought-provoking episode of the Rocket Chiro Podcast, Jerry Kennedy welcomes returning guest Shaq Smith for an unstructured but incredibly relevant conversation about a cultural shift in healthcare trust—especially among Gen Z—and what that means for chiropractors moving forward. Together, they unpack a global study by Edelman shared via Axios that reveals rising distrust in the medical establishment, and how younger generations are increasingly turning to social media, family, and AI instead of doctors for healthcare advice. This episode is not about fear or doom. It's about opportunity. Jerry and Shaq discuss how chiropractors can thrive in this new environment—by becoming approachable, authentic, and collaborative. If you want to know how to build real trust in a skeptical world, this episode is for you. Topics Covered Breakdown of the Edelman Study 16,000 adults surveyed across 16 countries Trust in traditional medical advice is plummeting Gen Z (ages 18–34) showed the sharpest decline in trust People now turn to friends, family, social media, and AI tools like ChatGPT for guidance Why This Matters for Chiropractors Many chiropractors misinterpret this shift as negative Jerry argues it's actually a massive opportunity People are more open than ever to alternative care But they're also more skeptical and cautious Key Insights for Chiropractors Approachability Over Authority Don't try to act like a hospital or medical institution Be authentic, human, and real Patients are drawn to approachable, relatable personalities—especially online Be a Trusted Peer, Not Just a Provider The age of “the man in the white coat” is fading Trust is built through transparency, consistency, and care Shaq shares real-world examples from social media and ad performance Collaborative Decision-Making is Crucial Chiropractic is a participation sport Patients don't want to be told what to do—they want to be heard Jerry shares the idea of “unburdening yourself” from outcomes, while still leading responsibly Office Design, Language, and Branding Your tone, attire, and environment matter more than ever Don't fake it. Be yourself—but be your best self Your online persona should match the in-office experience Retention Through Relationship True retention isn't just about visit numbers It's about maintaining a long-term doctor-patient relationship “If they're going to see a chiropractor five times in the next 20 years—make sure it's you.” Practical Takeaways Be visible and real online—smile in your photos, show personality in your videos Ditch manipulative sales tactics—people will bolt if they sense even a whiff of deception Use AI tools to enhance patient understanding, not replace your role Build trust over time—especially with younger patients who are used to doing their own research Engage in local Facebook groups or community platforms to stay involved without relying solely on ads About the Guest Shaq Smith is a marketing and social media strategist who specializes in helping chiropractors create content and ads that convert. Known for his sharp insights and practical advice, Shaq brings a younger generational perspective to the conversation—especially relevant for understanding Gen Z patient behavior. Final Thoughts This episode challenges chiropractors to stop chasing mainstream status and start leaning into what makes them different. Trust isn't dead—it's just shifting. And chiropractors who embrace approachability, authenticity, and patient participation will thrive in this new era. Want Help Growing Your Practice? Jerry offers business coaching, website design, SEO, and Google Ads services specifically for chiropractors. If you're ready for less stress and more momentum, visit RocketChiro.com. Free New Patient Search Review: https://rocketchiro.com/chiropractic-practice-assessment Best chiropractic websites: https://rocketchiro.com/best-chiropractic-websites Chiropractic SEO: https://rocketchiro.com/chiropractic-seo Coaching for Chiropractors: https://rocketchiro.com/join
Matt and Allie visit our Oakley center to speak to center manager Jeff Mischnick, PT MPT and his patient Jennelle. You'll hear about how Jennelle got injured and her experience with Jeff and PTA Quinten. Jeff describes the exercises used to treat her posture, neck pain, and ultimately her shoulder. Jennelle shares how she felt after receiving these treatments and gives her glowing review. Jenelle tells us she has written a couple books ready to be published, keep an eye out online!Did you know that you don't need a doctor's prescription to receive physical therapy? The laws of Direct Access allow you to receive physical therapy without a referral and still use your insurance benefits! Learn more on how Direct Access can help YOU! Our website: https://www.oxfordphysicaltherapy.com/
This week's topics include the worldwide burden of skin cancers, risk of a second stroke when a person is taking anticoagulants, patients supporting each other for weight loss maintenance, and imaging for dense breasts.Program notes:0:45 Dense breast tissue imaging1:40 MRI and contrast enhanced mammography superior2:40 Giving IV contrast with mammography2:53 Burden of skin cancer in older adults worldwide3:52 Greater disease burden in men4:53 More likely to have exam and biopsy5:48 Atrial fibrillation, recurrent stroke risk and anticoagulants6:50 One in six will recur7:50 Atrial appendage occulsion?8:20 Patient delivered weight loss management9:20 Five percent or greater initial weight loss10:20 Reduced the amount of weight regain11:22 Much less than a professional's care12:49 End
Patience extends beyond yourself to your interactions with others. This session focuses on cultivating a deep, compassionate presence when engaging with those around you, especially when faced with differing opinions, or challenging behaviors. Ancient Wisdom Weave: Draw on the Buddhist concept of (compassion) and the importance of loving-kindness in all relationships. THIS WEEK'S THEME: "The Patient Heart: Cultivating Inner Stillness" Welcome to "The Patient Heart: Cultivating Inner Stillness," a 7-part meditation series designed to help you rediscover the profound power and peace found in patience. In a world that often demands instant gratification, true tranquility lies in our ability to wait, to observe, and to trust in the natural unfolding of life. Drawing upon the timeless wisdom of ancient traditions, this series will guide you to cultivate patience not as passive waiting, but as an active, compassionate engagement with the present moment. Each episode offers a unique lens to understand and embody this vital virtue, fostering inner resilience and a deeper connection to the rhythm of existence. YOUR MEDITATION JOURNEY DURING THIS WEEK'S SERIES This is episode 5 of a 7-day meditation series titled, "The Patient Heart: Cultivating Inner Stillness" episodes 3311-3316. Day 1: Patience Visualization Day 2: Patience Affirmation: "I unfold with patience, presence, and peace." Day 3: Patience Breathing Visualization Day 4: Lotus Mudra for Patience Day 5: Fourth Chakra focus for Patience Day 6: Patience flow meditation combining the week's techniques. Day 7: Weekly review meditation and closure. WEEKLY CHALLENGE: The Pause Pivot Challenge THE PAUSE (Awareness): When you feel that familiar tug of impatience (the urge to rush, frustration, annoyance, a sigh, tapping your foot, etc.), immediately internally say to yourself: "Aha! A Patience Opportunity!" Take one deep, intentional breath. Notice the sensations in your body and mind without judgment. This is your "Pause." THE PIVOT (Choice): After that single breath, consciously choose a patient response, even if it's small. This isn't about solving the problem instantly, but shifting your internal state. SHARE YOUR MEDITATION JOURNEY WITH YOUR FELLOW MEDITATORS Let's connect and inspire each other! Please share a little about how meditation has helped you by reaching out to me at Mary@SipandOm.com or better yet -- direct message me at https://www.instagram.com/sip.and.om. We'd love to hear about your meditation ritual! SUBSCRIBE, LEAVE A REVIEW + TAKE OUR SURVEY SUBSCRIBE so you don't miss a single episode. Consistency is the KEY to a successful meditation ritual. SHARE the podcast with someone who could use a little extra support. I'd be honored if you left me a podcast review. If you do, please email me at Mary@sipandom.com and let me know a little about yourself and how meditation has helped you. I'd love to share your journey to inspire fellow meditators on the podcast! SURVEY: Help us get to know more about how best to serve you by taking our demographics survey: https://survey.libsyn.com/thedailymeditationpodcast FOR DAILY EXTRA SUPPORT OUTSIDE THE PODCAST Each day's meditation techniques posted at: sip.and.om Instagram https://www.instagram.com/sip.and.om/ sip and om Facebook https://www.facebook.com/SipandOm/ A DIFFERENT MEDITATION TECHNIQUE EVERY DAY FOCUSED ON A WEEKLY THEME: Get ready for an exciting journey with a new meditation technique daily, perfectly tailored to the week's theme! Infuse these powerful practices into the most stressful moments of your day to master difficult emotions. These dynamic techniques will help you tame the "monkey mind," keeping your thoughts from interrupting your meditation and bringing peace and focus to your life. FREE TOOLS: For free meditation tools to help you meditate please head over to my website at www.SipandOm.com, and there you'll find free resources to help you on your Meditation Journey. Enjoy access to more than 3,000 guided meditations without ads on the Sip and Om app. Try it for 7 days of free access to the full app! Listen on iTunes for 1-Week Free! https://itunes.apple.com/us/app/sip-and-om/id1216664612?platform=iphone&preserveScrollPosition=true#platform/iphone 1-week Free Access to the Android app! https://play.google.com/store/apps/details?id=com.sipandom.sipandom ***All meditations are Mary Meckley's original copyrighted content unless otherwise stated, and may not be shared without her written permission. RESOURCES Music composed by Christopher Lloyd Clark licensed by RoyaltyFreeMusic.com, and also by musician Greg Keller. I'D LOVE TO HEAR FROM YOU I'd love your feedback! Please let me know how you're enjoying the meditations by leaving me a review on iTunes. **All of the information shared on this podcast is for your enjoyment only. Please don't consider the meditation techniques, herbal tea information, or other information shared by Mary Meckley or any of her guests as a replacement for any medical or psychological treatment. That being said, please enjoy any peace, energy, or clarity you may experience as you meditate. SHARE YOUR MEDITATION JOURNEY WITH YOUR FELLOW MEDITATORS Let's connect and inspire each other! Please share a little about how meditation has helped you by reaching out to me at Mary@SipandOm.com or better yet -- direct message me at https://www.instagram.com/sip.and.om. We'd love to hear about your meditation ritual! SUBSCRIBE, LEAVE A REVIEW + TAKE OUR SURVEY SUBSCRIBE so you don't miss a single episode. Consistency is the KEY to a successful meditation ritual. SHARE the podcast with someone who could use a little extra support. I'd be honored if you left me a podcast review. If you do, please email me at Mary@sipandom.com and let me know a little about yourself and how meditation has helped you. I'd love to share your journey to inspire fellow meditators on the podcast! SURVEY: Help us get to know more about how best to serve you by taking our demographics survey: https://survey.libsyn.com/thedailymeditationpodcast FOR DAILY EXTRA SUPPORT OUTSIDE THE PODCAST Each day's meditation techniques posted at: sip.and.om Instagram https://www.instagram.com/sip.and.om/ sip and om Facebook https://www.facebook.com/SipandOm/ A DIFFERENT MEDITATION TECHNIQUE EVERY DAY FOCUSED ON A WEEKLY THEME: Get ready for an exciting journey with a new meditation technique daily, perfectly tailored to the week's theme! Infuse these powerful practices into the most stressful moments of your day to master difficult emotions. These dynamic techniques will help you tame the "monkey mind," keeping your thoughts from interrupting your meditation and bringing peace and focus to your life. FREE TOOLS: For free meditation tools to help you meditate please head over to my website at www.SipandOm.com, and there you'll find free resources to help you on your Meditation Journey. Enjoy access to more than 3,000 guided meditations without ads on the Sip and Om app. Try it for 7 days of free access to the full app! Listen on iTunes for 1-Week Free! https://itunes.apple.com/us/app/sip-and-om/id1216664612?platform=iphone&preserveScrollPosition=true#platform/iphone 1-week Free Access to the Android app! https://play.google.com/store/apps/details?id=com.sipandom.sipandom ***All meditations are Mary Meckley's original copyrighted content unless otherwise stated, and may not be shared without her written permission. RESOURCES Music composed by Christopher Lloyd Clark licensed by RoyaltyFreeMusic.com, and also by musician Greg Keller. I'D LOVE TO HEAR FROM YOU I'd love your feedback! Please let me know how you're enjoying the meditations by leaving me a review on iTunes. **All of the information shared on this podcast is for your enjoyment only. Please don't consider the meditation techniques, herbal tea information, or other information shared by Mary Meckley or any of her guests as a replacement for any medical or psychological treatment. That being said, please enjoy any peace, energy, or clarity you may experience as you meditate.
Read Online“When a woman is in labor, she is in anguish because her hour has arrived; but when she has given birth to a child, she no longer remembers the pain because of her joy that a child has been born into the world.” John 16:21This truth can certainly be extended to any form of anguish we experience for a good reason. Note that the pain experienced in childbirth is pain for a good and holy reason. Therefore, the pain is forgotten, in a sense, when the mother sees and holds her newborn child. That suffering is forgotten in the sense that it is transformed into joy by the birth of a child.There is much in life that can cause anguish. In today's Gospel, Jesus goes on to say to His disciples: “So you also are now in anguish.” He says this because He had just finished speaking to them about His coming departure to the Father and about the suffering that they would all experience in the form of persecution. But then He says to them that after He departs and they no longer see Him, they will then see Him again and will rejoice. And He says, “On that day you will not question me about anything.” This is an important line to understand.Anguish, or any form of suffering, can tempt us to question our lives and even to question God. It is clear that after Jesus was killed, the disciples questioned everything. They were confused and frightened. All appeared to be lost. Then, to a lesser degree, after Jesus ascended into Heaven and prior to Him sending the Holy Spirit, the disciples would have also experienced confusion. Why did Jesus leave them? Why didn't He stay longer? Who was going to lead them now? These and many other similar questions would have arisen in their minds.So also with us, when things do not go as planned, or when things take a painful turn in our lives, we can immediately question and even doubt the perfect plan of God. If things fall apart because of our sin, then repentance is the remedy. But if things fall apart, in the sense that life becomes difficult, then we should especially listen to the words of Jesus today.When anguish in life happens because we are fulfilling God's will, we must see that anguish as a means to a much greater good. Just as the pains of childbirth lead to the gift of a child, so the pains of bringing forth God's will in our lives will lead to the presence of God Himself. Patient endurance is a virtue that is especially important in this case. For example, the anguish of overcoming an addiction, or of praying when we don't feel like praying, or of forgiving someone who hurt us are all examples of anguish turning into blessings. Very often, combatting our own selfish will is difficult. But the fruit of engaging in such a battle within us is joy. There is joy found in victory over sin. Joy is found in persevering in prayer. Joy is found in every difficulty we endure for the Kingdom of God. But the joy is not always our first experience. It is only experienced when we patiently endure the situation.Reflect, today, upon any form of anguish you are currently enduring for the glory of God, or anything you are currently avoiding because it seems difficult to do. Do not shy away from these difficulties. See them as a means to a glorious end. Endure the “labor pains” of the purification and mission God is calling you to by looking beyond the difficulties you initially experience so that you will see the end result that awaits you.My glorious Lord, You endured Your passion with perfect virtue. You never wavered from fulfilling the will of the Father, and the fruit of Your perseverance was the glory of the Resurrection. Please help me to patiently endure the crosses in my life and give me hope to see that from them You will bring forth the good fruit of eternal joy. Jesus, I trust in You.Image: Image via Adobe StockSource of content: catholic-daily-reflections.comCopyright © 2025 My Catholic Life! Inc. All rights reserved. Used with permission via RSS feed.
In this episode of FYI – For Your Innovation, Brett Winton and ARK analyst Nemo Despot sit down with Generate Biomedicines CEO Mike Nally and CFO Jason Silvers to explore how generative AI is transforming the discovery and development of protein-based therapeutics. Founded in 2018 by Flagship Pioneering, Generate Biomedicines is building a “self-driving lab” that combines machine learning, cryo-electron microscopy (cryo-EM), and high-throughput wet lab automation to dramatically accelerate drug development. The conversation dives into how Generate is reimagining protein therapeutics — going beyond trial-and-error methods to a data-first, design-driven model for creating novel medicines. The team discusses the company's proprietary approach to integrating structural biology with functional data, the economic implications of reducing time-to-market from 13 years to under 9, and how their platform could unlock treatments for diseases that have been historically undruggable. They also touch on strategic partnerships, scalability, and how AI is shifting the biotech business model from artisanal science to an industrialized, data-driven enterprise.Key Points From This Episode:00:01:30 Why Generate Biomedicines is rethinking protein drug discovery from first principles00:04:40 How their structure-first approach differs from peers like AbSci and Recursion00:07:04 Using cryo-EM to build proprietary protein interaction datasets00:10:57 Traditional drug discovery is random, expensive, and inefficient — here's how Generate is changing that00:16:58 From concept to clinic in 18–24 months: Accelerating timelines through AI00:20:47 Going beyond efficiency: Unlocking access to undruggable biology00:24:48 Turning cryo-EM into a high-throughput data engine for model training00:31:20 The long-term vision: Patient-specific protein therapeutics00:40:00 Why scalability gives Generate an edge over traditional biotech00:47:52 The future of biotech as a research & development (R&D) sharing economy00:54:19 Adapting fast: Keeping pace with generative AI advances across the stack01:00:16 The KPI (key performance indicator) for platform success: Rate of improvement
Some patients' lives are so complicated by trauma, poverty and other social problems that routine conditions like diabetes and asthma regularly turn into $10,000 hospital visits. America's health care leaders have spent years trying to help this small but costly group of patients. What have they learned?Guests:Jeff Brenner, MD, CEO, The Jewish BoardArthur Brown, Client, Camden CoalitionAmy Finkelstein, PhD, Professor of Economics, MIT; Co-Scientific Director, J-PAL North AmericaAllison Hamblin, MSPH, President and CEO, Center for Health Care StrategiesPaula Lantz, PhD, Professor of Health Policy, University of MichiganLarry Moore, Client, Camden CoalitionKathleen Noonan, JD, President and CEO, Camden CoalitionDottie Scott, Community Health Worker, Camden CoalitionBrian Thompson, Housing Coordinator, Camden CoalitionLeslie Walker, Senior Producer/Reporter, TradeoffsLearn more and read a full transcript on our website.Join us for a virtual discussion with Penn LDI on June 6 at 12 pm ET, where Penn experts will help us understand the programs targeted by federal cuts to violence prevention programs, the lessons we've learned about how to prevent gun violence, and what the administration's actions could mean for communities impacted by this uniquely American epidemic. Learn more and register here. Want more Tradeoffs? Sign up for our free weekly newsletter featuring the latest health policy research and news.Support this type of journalism today, with a gift. Hosted on Acast. See acast.com/privacy for more information.
It's Thursday, May 29th, A.D. 2025. This is The Worldview in 5 Minutes heard on 125 radio stations and at www.TheWorldview.com. I'm Adam McManus. (Adam@TheWorldview.com) By Jonathan Clark Christianity growing in Asia despite persecution International Christian Concern reports that Christianity is growing in Asia despite severe persecution. In 2024, there were 415 million Christians in Asia, making up 8% of the continent's population. That's up from 3% in 2010. Since 2020, Christianity's growth rate in Asia has been 1.6% per year. The church is growing in Communist, Buddhist, and Islam-dominated countries like China, Laos, Malaysia, Indonesia, Vietnam, and Myanmar. All this growth continues despite persecution in the from of harassment, anti-conversion laws, restrictions on Bibles, arrests, imprisonments, and even violence and murder. In 2 Corinthians 4:8-10, the Apostle Paul wrote, “We are hard-pressed on every side, yet not crushed . … persecuted, but not forsaken … always carrying about in the body the dying of the Lord Jesus, that the life of Jesus also may be manifested in our body.” 50% of kids in United Kingdom do not live with both biological parents Research from the Marriage Foundation found that nearly half of children in the United Kingdom do not live with both of their biological parents. The report showed a record 45% of teenagers are not living with both parents by the age of 14. This trend is not driven by divorce which is at its lowest level since 1970. Instead, family breakdown is driven by a collapse in marriage rates. Harry Benson, the Research Director for the Marriage Foundation, said, “The level of family breakdown in the UK is at epidemic proportions and is set to get worse.” French House voted to legalize assisted suicide France's National Assembly voted in favor of a bill to legalize assisted suicide on Tuesday. The measure allows adult patients with painful and incurable illness to take a lethal substance. The bill must also pass in France's Senate. Matt Vallière, the Executive Director of the Patients' Rights Action Fund, warned, “The French National Assembly cast a fateful and terrible vote that will put a great many at risk of deadly harm and discrimination under an unprecedented euthanasia regime.” Proverbs 12:10 says, “The tender mercies of the wicked are cruel.” Supremes declines case of Christian kid's t-shirt affirming 2 genders In the United States, the Supreme Court declined to hear a free speech case Tuesday. The case involves a Massachusetts public school student named Liam Morrison. In 2023, he wore a T-shirt to class that said, “There are only 2 genders.” In response, the school banned him from wearing the shirt. The Morrison family challenged the decision; however, the courts ruled against them. Supreme Court Justice Samuel Alito authored a dissenting opinion to the court's decision to not hear the case. He said the free speech case “presents an issue of great importance for our Nation's youth.” Listen to viral comments from Liam, the boy at the epicenter. He made them before his school board. MORRISON: “What did my shirt say? Five simple words. ‘There are only two genders.' Nothing harmful, nothing threatening. Just a statement I believe to be a fact. “I have been told that my shirt was targeting a protected class. Who is this protected class? Are their feelings more important than my rights? … “Not one person, staff or student, told me that they were bothered by what I was wearing. Actually, just the opposite. Several kids told me that they supported my actions and that they wanted one too.” Defense Secretary Hegseth affirms homeschooling for military families Earlier this month, U.S. Defense Secretary Pete Hegseth ordered the department to review how well it supports homeschooling for military families. The directive follows an executive order from President Donald Trump on supporting school choice in the military. Hegseth wrote, “Homeschooling offers an individualized approach for students and highlights the significant role parents play in the educational process.” Liberal Presbyterian Church (USA) keeps losing members The Presbyterian Church (USA) lost nearly 50,000 members last year according to its latest report. The liberal denomination has been losing a similar number of members each year since the COVID-19 pandemic. Their unbiblical stands have cemented their own demise. In 2014, it voted to allow pastors to marry two homosexual men or two lesbians. Plus, PC(USA) contends that there should be no laws restricting abortion. At its current rate of decline, the PC(USA) will likely fall below one million members this year. Protestors harass Christians promoting Biblically-defined family, sexuality And finally, MayDay USA held a prayer event in Seattle, Washington last Saturday. The group gathers Christians to seek God, proclaim the Gospel, and promote the “sacredness of gender and family as defined by God.” In response, violent rioters, including Antifa members, showed up to harass the Christians. This ended in police making over 20 arrests. Sadly, Seattle Mayor Bruce Harrell blamed the Christians for the violence. In response, FBI Deputy Director Dan Bongino announced, “We have asked our team to fully investigate allegations of targeted violence against religious groups at the Seattle concert. Freedom of religion isn't a suggestion.” Close And that's The Worldview on this Thursday, May 29th, in the year of our Lord 2025. Subscribe for free by Spotify, Amazon Music or by iTunes or email to our unique Christian newscast at www.TheWorldview.com. Or get the Generations app through Google Play or The App Store. I'm Adam McManus (Adam@TheWorldview.com). Seize the day for Jesus Christ.
Bret speaks with Dr. Lon Jones, DO on the subject of the mismatch between modern humans and the environment they live in. Find Dr. Lon Jones, DO at https://commonsensemedicine.org*****Join DarkHorse on Locals! Get access to our Discord server, exclusive live streams, live chats for all streams, and early access to many podcasts: https://darkhorse.locals.comCheck out the DHP store! Epic tabby, digital book burning, saddle up the dire wolves, and more: https://www.darkhorsestore.orgTheme Music: Thank you to Martin Molin of Wintergatan for providing us the rights to use their excellent music.*****Mentioned in this episode:- Common Sense Medicine: Making America Healthy Again by Dr. Lon Jones, DO https://amzn.to/4kd4mka (commission earned)- No More Allergies, Asthma or Sinus Infections: The Revolutionary Approach by Dr. Lon Jones, DO https://amzn.to/4dKaa2o (commission earned)- George Williams Paper: Pleiotropy, Natural Selection, and the Evolution of Senescence https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1558-5646.1957.tb02911.x - Patient education: Ear infections (otitis media) in children (Beyond the Basics) https://www.uptodate.com/contents/ear-infections-otitis-media-in-children-beyond-the-basics/print - Indirect health effects of relative humidity in indoor environments https://pmc.ncbi.nlm.nih.gov/articles/PMC1474709/ - Turku sugar studies V: Final report on the effect of sucrose, fructose and xylitol diets on the caries incidence in man https://www.tandfonline.com/doi/abs/10.3109/00016357608997711 - Paul W. Ewald: Evolution of Disease https://amzn.to/4dzIzRj (commission earned)- Commonsense Medicine: Healing from the Inside Out and Stopping the Next Pandemic https://amzn.to/4kE9kX7 (commission earned)- How Bacteria Stick https://www.scientificamerican.com/article/how-bacteria-stick Support the show