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Alzheimer's disease has grown to become the most common form of dementia, and as of now, there is no cure for this devastating neurodegenerative disease. But new science shows that your brain's immune cells play an essential role in how your brain ages. Today, you're going to learn this latest science and how to put it into action. Today's guest, Dr. David Perlmutter is a board-certified neurologist and six-time New York Times bestselling author. His new book, Brain Defenders, dives into the groundbreaking discovery that immune cells in the brain are the key to brain health and longevity. On this episode, you're going to learn about this emerging science and what you can do to protect your brain now and as you age. In this interview, you're going to learn about the fascinating science of immunometabolism, what microglial cells are, and the specific lifestyle habits that can shape the future of your brain. We're going to talk about specific foods and exercises that can dictate the health of your brain's immune cells, and proven strategies to protect your brain from degradation. Enjoy! In this episode you'll discover: The one fundamental mechanism that connects all neurodegenerative diseases. (2:26) What the latest science says about the efficacy of Alzheimer's medications. (3:41) The essential function of microglial cells. (6:51) What immunometabolism is. (8:41) How having type 2 diabetes can increase your risk of Alzheimer's disease. (11:23) What GLP-1 drugs teach us about the link between the brain and metabolism. (12:12) How exercise helps defend the brain from degeneration. (29:12) The connection between myokines and metabolism. (29:54) Why flexibility and balance training are important for longevity. (36:57) The truth about fish oil supplements for brain health. (38:14) What to eat to defend your brain. (42:21) How eating ultraprocessed foods increases your risk of brain diseases. (45:38) Why stress impacts your brain health. (57:10) The simplest way to measure your health and activity levels. (1:08:23) Items mentioned in this episode include: DrinkLMNT.com/model - Get a truly meaningful dose of electrolytes in a science-backed ratio. Free sample pack with any order. Organifi.com/Model - Organifi makes nutrition easy and delicious for everyone. Take 20% off your order with the code MODEL. Brain Defenders by Dr. David Perlmutter - Preorder your copy of Dr. Perlmutter's new book today! Grain Brain by Dr. David Perlmutter - Read about how your diet affects your brain health! You've Been Pooping All Wrong by Dr. Trisha Pasricha - Learn about gut health and how to poop better! Connect with Dr. David Perlmutter Website / Podcast / Facebook / Instagram Be sure you are subscribed to this podcast to automatically receive your episodes: Apple Podcasts Spotify Soundcloud Pandora YouTube This episode of The Model Health Show is brought to you by LMNT and Organifi. Most people are underhydrated—and it's costing you energy, focus, and performance. LMNT delivers a science-backed electrolyte ratio with no sugar, no junk—just what your body actually needs. Get a free sample pack with any order at drinklmnt.com/model. Make nutrition effortless—and actually enjoyable. Organifi's delicious, superfood blends help you boost energy, reduce stress, and feel your best every day. Get 20% off with code MODEL at organifi.com/model.
On today's Bible Answer Man broadcast (08/03/26), Hank answers the following questions:What do you believe is the purpose of the Body of Christ? Steve - WI (0:58)Several places in the New Testament say the whoremonger will not see heaven. What about pornography? Kendal - SD (2:55)Does the soul leave the body of people with dementia or Alzheimer's? Are they accountable for their actions in that state? Rob - Oklahoma City, OK (6:59)Is there such a thing as a spirit of fear or anger? Jason - NC (15:43)Did we get the leap year from Joshua 10 when the sun stood still? Guy - PA (19:08)What is the fate of those who never heard the Gospel? How could a loving God create people that He knows will go to hell? Chris - Allentown, PA (23:02)
Dans cet épisode, nous abordons un sujet essentiel, souvent évoqué mais rarement approfondi : l'éthique clinique.Notre invité, Jean Matos, accompagne depuis des années les établissements médico-sociaux dans la mise en place d'espaces de réflexion éthique. Son approche est claire : l'éthique n'apporte pas des solutions toutes faites, elle aide à se poser les bonnes questions.L'éthique clinique, c'est apprendre à regarder autrement les situations de soin, à prendre du recul, à adapter sa pratique à chaque personne. Ce n'est pas une théorie lointaine, mais un outil concret de bientraitance et de discernement collectif.Au fil de la discussion, plusieurs dilemmes du quotidien sont évoqués : la contention, la consommation d'alcool, la sexualité, le temps accordé à chacun… Autant de situations où les valeurs d'autonomie, de sécurité, de liberté ou de bienfaisance peuvent entrer en tension.Jean Matos rappelle l'importance d'un regard extérieur, d'un facilitateur éthique capable de libérer la parole des équipes, de créer un espace d'échange où chacun, quel que soit son rôle, peut exprimer son ressenti sans jugement.Car l'éthique, c'est d'abord une éthique de la discussion.Les établissements sont aujourd'hui invités à formaliser cette démarche.Les nouvelles grilles d'évaluation intègrent l'éthique au même titre que la qualité du soin ou la bientraitance.Mettre en place un comité éthique, c'est offrir un lieu d'éclairage et non de décision, un espace pour prévenir les tensions avant qu'elles ne deviennent des “malaises profonds” dans les équipes.Autre sujet émergent : l'intelligence artificielle en EHPAD.Des outils comme les robots d'accompagnement ouvrent de nouvelles perspectives thérapeutiques, mais posent aussi de vraies questions éthiques.Jean Matos invite à ne pas craindre ces technologies, mais à les apprivoiser avec lucidité : ni fascination, ni rejet, mais réflexion.Son message est simple :Prendre le temps de la réflexion éthique, c'est prendre soin de ceux qui soignent.C'est un investissement gagnant : des équipes plus apaisées, des pratiques plus justes, un accompagnement plus humain.
Actinogen Medical Ltd managing director and CEO Dr Steven Gourlay talked with Proactive about the company's June quarter progress, including preparations for the pivotal XanaMIA Alzheimer's disease trial topline results expected in November 2026. Gourlay said the fully enrolled Phase 2b/3 trial remained on schedule, with treatment, follow-up and data-cleaning activities continuing across participating sites. He described the upcoming readout as “a potentially transformational event for the company and for the clinical science, and for patients with Alzheimer's all around the world.” An independent Data Monitoring Committee completed its third review of safety data from all 247 trial participants and recommended that the study continue without amendment. Actinogen Medical ended the quarter with $16.7 million in cash. Chief Financial Officer Will Souter said the company's current funding position was expected to support operations beyond the XanaMIA results and into mid-2027. He also highlighted potential additional funding sources, including an anticipated research and development tax rebate and the possible exercise of listed and unlisted options. Gourlay also discussed positive depression trial data published in the British Journal of Psychiatry and the company's continuing engagement with regulators, including the US Food and Drug Administration and the European Medicines Agency. Visit Proactive's YouTube channel for more company interviews and market updates. Please give the video a like, subscribe to the channel and enable notifications for future content.
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Researchers have identified a new blood test that could reveal signs of Alzheimer's disease decades earlier than ever before.The potential breakthrough is just the latest piece of positive news when it comes to identifying and treating dementia patients — including the recent approval of a long-awaited drug that slows the progression of early-stage Alzheimer's disease.On a recent episode of Village Media's Closer Look podcast, we sat down with one of Canada's leading experts on dementia: Dr. Howard Chertkow, a senior scientist at the Baycrest Academy for Research and Education.He talked about why he thinks this could be a “turnaround decade” in the treatment, prevention and early diagnosis of Alzheimer's disease.Reach out to Frisco and Scott
Crossing the English Channel is one of the world's most demanding endurance challenges. For Camp Hill swimmer Jeannie Zappe, completing the feat for a second time was about much more than athletic achievement—it was a mission fueled by love, resilience and a desire to raise awareness for Alzheimer's disease. Kim Miller, the eldest daughter of Sight & Sound founders Glenn and Shirley Eshelman, will discuss the theater's 50-year journey, sharing personal stories about its history, the 1997 fire, the rebuilding process, and the ministry's growth and expansion. The interview will reflect on Sight & Sound's milestone anniversary, exploring how the organization has evolved from its early years to where it stands today.
Send us Fan MailSenior Living Guide.com podcastGuest: Darleen Mahoney"Don't you let anyone should on you. And don't you should on anyone else." is the actual quote that came from the Terrible, Thanks for Asking podcast. Apparently my brain changed it to "don't should all over yourself". :)Support the Alzheimer's & Dementia Resource Center
Läkaren Moa Wibom svarar på läsarnas egna frågor: Vilka symtom ska man vara uppmärksam på om man misstänker Alzheimer? Hur går det till att utreda Alzheimer? Vad gör man om man misstänker att diagnosen är fel? Hur ser de olika stadierna ut i sjukdomen? Min mamma har Alzheimer. Bör jag kolla upp mig? Hur ser hjälpen ut om jag sedan får en diagnos? Poddavsnittet produceras av Alzheimer Life med stöd av Lilly.
They say you're never too old to learn something new, and one Kiwi entrepreneur is using this as the basis for her new education initiative. Frances Valintine recently launched the Love Heart Social Learning programme, and it's designed to educate Kiwis over 60 and encourage connection. She says she's been working in education for years and seen Kiwis in their late 40s and beyond return for masters degrees and she felt inspired to use this for a social enterprise. "It's extraordinarily important, all the studies have come out around cognitive decline, Alzheimer's', dementia, etc - a lot of it comes through loneliness and lack of connection to people, but also the lack of keeping your mind busy. So people often take up reading or they go into book clubs, they might do other things that they haven't done before." LISTEN ABOVESee omnystudio.com/listener for privacy information.
Viagra's Cancer Signal, TV's Toll on Your Brain, Heat and Accelerated Aging, and a New Way to Flush Your Brain Explained Viagra's Active Ingredient May Block Cancer From Spreading A study published in Cancer Research from the Weizmann Institute of Science, in collaboration with Clalit and the U.S. National Cancer Institute, found that sildenafil, the active ingredient in Viagra, may interfere with cancer cells' ability to metastasize by disrupting how they regulate cholesterol, a resource tumors need to detach and invade new tissue. The team combined mouse models and human cell cultures with more than twenty years of medical records covering roughly five million people, and found better survival outcomes among about forty thousand cancer patients who had taken sildenafil before diagnosis. Researchers also flagged a possible combination effect with statins. Host Dave Asprey breaks down why this cheap, off-patent drug class deserves more attention than it's getting, and where it fits alongside his own longevity protocol. Source: https://www.healthline.com/health-news/viagra-may-stop-cancer-from-spreading-study ~~ Heavy TV Watching In Midlife Tied To Alzheimer's-Related Brain Changes A nearly twenty-four-year study published in Alzheimer's & Dementia followed more than 1,700 adults, tracking TV habits in their early fifties and scanning their brains in their mid-seventies. Men who watched more TV showed greater white matter damage and smaller frontal and occipital lobes, while women showed no such association. Critically, people with desk jobs that kept them sedentary all day did not show the same brain changes, and the TV association held even after adjusting for exercise levels. Host Dave Asprey unpacks why passive screen time, not sitting itself, may be the real driver here. Sources: https://www.the-independent.com/life-style/tv-time-linked-alzheimers-study-b3023054.html https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/alz.71582 ~~ Ambient Heat Exposure Linked To Faster Biological Aging A Science Advances study of 3,686 older adults linked neighborhood-level heat index exposure to accelerated biological aging using DNA methylation clocks. Short-term heat exposure moved one clock significantly, while exposure sustained over a full year or six years moved all major clocks, with extreme-caution heat days tied to nearly a three-year jump in one aging measure and a five percent faster overall aging pace on another. Researchers point to inflammation and stress signaling as likely drivers. Host Dave Asprey explains why this is a fundamentally different kind of heat story than the sauna and cold-plunge conversation biohackers are used to. Source: https://www.science.org/doi/10.1126/sciadv.adr0616 ~~ Industrial Chicken Farming May Be Accelerating The Spread Of Drug-Resistant Bacteria A genomic analysis of nearly 2,800 bacterial samples from chickens and wild birds across thirty countries, published in PNAS and covered by The Guardian, found a roughly hundredfold increase in Campylobacter strain transitions between wild birds and farmed chickens since 1900. Global chicken populations have grown sevenfold since the 1960s to about 27 billion birds, and researchers identified genetic adaptations tied to antimicrobial resistance developing inside that population. Sixty to eighty percent of human Campylobacter infections trace back to raw chicken, with links to post-infectious IBS in some cases. Host Dave Asprey connects the dots between industrial farming density and the gut-health stakes for anyone who eats chicken. Sources: https://www.theguardian.com/food/2026/jul/27/industrial-chicken-farming-accelerating-spread-of-diarrhoea-bacteria-study-finds https://doi.org/10.1073/pnas.2609969123 ~~ VA Researchers Develop Breathing-Based "Brain Flush" For Parkinson's And Alzheimer's VA researchers led by Dr. Henry Lin found a way to trigger the brain's glymphatic clearance system, normally active during deep sleep, in people who are awake, using alternating puffs of five percent carbon dioxide and room air every thirty-five seconds. In a study of thirty Parkinson's patients and thirty-three healthy controls, a single thirty-minute session produced measurable increases in blood levels of beta-amyloid, alpha-synuclein, and other waste proteins associated with neurodegeneration. The VA's Technology Transfer Program is now developing a patent and prototype device. Host Dave Asprey explains why this gives breathwork protocols a real physiological mechanism instead of just a hunch. Source: https://www.research.va.gov/currents/0426-Exciting-new-treatment-being-developed-for-Parkinsons-Alzheimers.cfm ~~~ This episode is designed for biohackers, longevity enthusiasts, and high-performance listeners who want mechanism-level insights into an overlooked cancer drug repurposing story, the real difference between passive and active screen time, a new angle on heat as a biological stressor, the hidden gut-health cost of industrial poultry farming, and a breathing technique that may unlock your brain's own detox system. Host Dave Asprey connects clinical research, large-scale genomic data, and translational neuroscience into practical frameworks for improving longevity, gut health, and brain performance. New episodes every Tuesday, Thursday, Friday, and Sunday. Keywords: sildenafil cancer metastasis, Viagra cancer research, cholesterol cancer cells, PDE5 inhibitor longevity, TV Alzheimer's risk, screen time dementia, white matter brain aging, passive sedentary behavior brain, ambient heat epigenetic aging, DNA methylation clock, heat index biological aging, industrial chicken farming bacteria, Campylobacter antibiotic resistance, foodborne illness IBS, glymphatic system brain flush, CO2 breathing brain detox, Parkinson's Alzheimer's treatment, VA brain research, biohacking news 2026, Dave Asprey, The Human Upgrade Thank you to our sponsors! - Suppgrade Labs | Get real restorative sleep with Quiet Mode. Use code DAVE15 at shopsuppgradelabs.com. - Timeline | Visit timeline.com/dave to learn more about Mitopure and get 20% off your first order for a limited time. - iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE Resources: • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Intro 00:19 – Story #1: Viagra & Cancer 02:01 – Story #2: TV Watching & Brain Aging 03:16 – Story #3: Heat Exposure & Biological Age 04:46 – Story #4: Chicken Farming 06:34 – Story #5: CO2 Therapy & Brain Detox See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Send us Fan MailThis week we're diving into Deep Blue Sea (1999). We look back on its stacked cast, dissect its balance of creature-feature and ethical sci-fi horror, and debate how its shark approach holds up against the Jaws legacy. This episode contains spoilers, beginning at 21:57.Mentioned in the EpisodeWatch the MovieDeep Blue Sea (1999)Related Episodes024: Scream (1996)097: Alien (1979)162: Jaws 2 (1978)222: Jaws 3-D (1983)279: Jaws: The Revenge (1987)416: Halloween H20: 20 Years Later (1998)Sharksploitation: 50 Years After Jaws (Video)Sharksploitation: 50 Years After Jaws (Episode)Main EpisodeSharksploitation: How Jaws Changed Horror and Shark Movies ForeverDeepest Bluest (Shark's Fin)How Deep Blue Sea's Most Shocking Death Was CreatedCutthroat Island (1995)The Long Kiss Goodnight (1996)Star Wars: Episode I – The Phantom Menace (1999)Sharknado (2013)Frankenstein (1931)Open Water (2003)Piranha (1978)Halloween: Resurrection (2002)Dangerous Animals (2025)Genetic engineeringAnimal testingAlzheimer's diseaseSupport the showThanks for listening to Hack or Slash! Want more from the show? Join us on Patreon for extended episodes, bonus reviews, B-sides, watchalongs, behind-the-scenes extras, and more ways to help keep the show alive and slashing.Support us on PatreonYou can also hang out with us between episodes in our community spaces. Join the Discord for watch parties, episode discussions, horror recommendations, and general spooky nonsense.Join our DiscordFollow Hack or Slash:WebsiteYouTubeRedditInstagramTikTokHave thoughts on this week's movie? Leave a comment, send us a voicemail, or tag us online. We love hearing your thoughts on the movies we cover.Happy slashing!Music Credits: "Hack or Slash" by Daniel Stapleton
Scientists have evidence chewing is good for the brain and can even ward-off Alzheimer's.
Program notes:0:44 Novel agent for acute pain1:44 Post-abdominal surgery and placebo, low and high dose2:46 Compared to placebo and opioids3:19 Metabolic associated steatotic liver disease4:19 Imaging with two techniques and plasma markers5:19 Imaging and composite scores for staging6:21 Identifying appropriate candidates for clinical trials7:00 Alcohol consumption during pregnancy8:00 Employed, tobacco use, and mental stress predicts9:01 Never tested medicines for AUD in pregnant women9:24 Early detection of Alzheimer's disease with circular RNA10:24 Can it identify those with the disease as well as those at risk11:24 Almost 95% AUC12:20 Use with tau, it was even better13:05 End
Hear the latest on blood-based biomarkers, lifestyle interventions, and more from AAIC 2026 with Gil Rabinovici, MD. Related Content: Soccer Players' Brains, P-Tau217 Blood Tests, Lifestyle and Dementia Risk, and More From AAIC 2026
Until his mother was diagnosed with Alzheimer's, Mark Wilson was a human resources executive at Taco Bell. Doctors gave his widowed mom six years to live. Mark retired, moved back home, back to the bedroom of his childhood. And he made a plan. He drew on his corporate experience to build a caregiving team of five aides who cared for his mother 24/7. He researched how particular foods might help his mother and he took over the cooking. He searched for a doctor to help his mother with a painful ailment unrelated to dementia. He found a guru! These are just a few of the steps he took, all of which are explored in his book, a memoir self-help book titled Breakthrough Alzheimer's Care. With the help of his sister and the breakthrough ideas in Mark's plan, their mom lived 15 more years, not 6. His website, BoldCareLeader.com, is full of helpful information and free resources.
Bruce Soord is the founder and principal songwriter of The Pineapple Thief. His latest solo album is an incredibly unguarded and emotionally direct work, shaped and informed by the long, drawn out death of his Father and his Mother's ongoing Alzheimer's. It is intense and beautiful, bare and unpredictable, aural grief in motion, amplifying the sudden surfacing of memory and the determination we all carry. Gleb Kolyadin is one of the most important and fascinating pianists working across a number of areas, from ballet to progressive rock and many stops in between. Kscope enthusiasts will recognise him from his work both solo and alongside Mariana Semkina in the award-winning chamber-prog duo iamthemorning. Bruce and host Billy Reeves discuss the generational trauma of aged parental cognitive decline, art-as-politics, AI versus AI slop, the decline of market towns, and his early days in his “funky-rock” student band under the arches in Leicester with his best friend and musical collaborator Jon Sykes. Gleb and Bruce talk about Gleb's personal and emotional involvement with the project: ie his reworking of the material into the Earbook second CD/album in its own right ‘Shipwrecks in the Harbour', the hours he feels most inspired, and whether working to a deadline for musicians can help or hinder. And, now he lives in the UK, has he finally been to the chip shop?
Join the Conversation at 303-477-5600 or text to 307-200-8222. Monday-Friday, 3 pm-6 pm MT. https://RushToReason.com Hour 1 Stage 4 Cancer, Heart Disease, and the Health Choices That Could Change Everything. Kick off Health and Wellness Wednesday with John Rush as he dissects new revelations about Anthony Fauci and the unresolved mysteries of the COVID era. Then, plunge into two gripping, real-life stories of defying the odds—where hope, healing, and prevention take center stage. What if stage 4 cancer isn't the end—but a new beginning? Emma Victoria Johnson reveals how she turned a devastating diagnosis into a story of hope, discovering lifesaving breakthroughs at Oasis of Hope. Hear how bold lifestyle changes, nutrition, and immune health fueled her fight for recovery. Next, Wayne Elliott recounts surviving a heart attack at just 35. Discover the unconventional choices he credits with transforming his life—and what most people overlook about heart health. Obesity, statins, Alzheimer's, toxins, and the daily habits that could change your future—don't miss these life-altering insights. John wraps up with a bold question: Is our addiction to convenience silently sabotaging our health? This hour is packed with inspiring stories, frank conversations, and eye-opening ideas that might just make you rethink your everyday choices. Timestamps 11:46 — Emma Victoria Johnson — https://www.oasisofhope.com 30:38 — Wayne Elliott — https://straussnaturals.com HOUR 2 Freedom, Socialism, Fauci, and Colorado's Political Crossroads. Start with a wake-up call: Richard Battle lays out why America stands at a crossroads—can free enterprise and liberty survive in a world drifting toward socialism? Hear powerful arguments for economic freedom, plus a candid look at inflation, government overreach, and immigration. John tackles Colorado's political storm, revealing why divided conservatives could see their state slip away for good. Sunny Kutcher of Young Americans Against Socialism brings the heat, exposing the rapid rise of socialist ideas and the high stakes for government accountability. Dive into Fauci's testimony, pandemic fallout, free speech battles, and border clashes—plus, why the next Colorado election could change everything. If you care about America's future, you can't afford to miss this. Timestamps 1:09 — Richard Battle — https://RichardBattle.com 30:37 — Sunny Kutcher — https://yaas.org Hour 3 COVID Secrets, AI Showdown, and Colorado's Tech Future Hang in the Balance Uncover the untold story behind COVID lockdowns as Michael Pack reveals what went into the making of ‘Lockdown Dissidents.' Go behind the scenes with Fauci's diary, the fallout of school closures, and the fight for civil liberties. John Rush pulls back the curtain on the backlash he faced for challenging the status quo—proving why questioning authority is more important than ever. Then, shift gears as Scott Garliss breaks down the high-stakes world of Wall Street and artificial intelligence—revealing how today's tech battles could decide America's financial future. John fires back at short-sighted tech critics, champions AI innovation, and explains why your vote could shape the next era of American leadership. Timestamps 1:07 — Michael Pack — https://palladiumpictures.com/ 28:34 — Scott Garliss — https://www.bentpinecapital.com/
Join the Conversation at 303-477-5600 or text to 307-200-8222. Monday-Friday, 3 pm-6 pm MT. https://RushToReason.com Hour 1 Stage 4 Cancer, Heart Disease, and the Health Choices That Could Change Everything. Kick off Health and Wellness Wednesday with John Rush as he dissects new revelations about Anthony Fauci and the unresolved mysteries of the COVID era. Then, plunge into two gripping, real-life stories of defying the odds—where hope, healing, and prevention take center stage. What if stage 4 cancer isn't the end—but a new beginning? Emma Victoria Johnson reveals how she turned a devastating diagnosis into a story of hope, discovering lifesaving breakthroughs at Oasis of Hope. Hear how bold lifestyle changes, nutrition, and immune health fueled her fight for recovery. Next, Wayne Elliott recounts surviving a heart attack at just 35. Discover the unconventional choices he credits with transforming his life—and what most people overlook about heart health. Obesity, statins, Alzheimer's, toxins, and the daily habits that could change your future—don't miss these life-altering insights. John wraps up with a bold question: Is our addiction to convenience silently sabotaging our health? This hour is packed with inspiring stories, frank conversations, and eye-opening ideas that might just make you rethink your everyday choices. Timestamps 11:46 — Emma Victoria Johnson — https://www.oasisofhope.com 30:38 — Wayne Elliott — https://straussnaturals.com HOUR 2 Freedom, Socialism, Fauci, and Colorado's Political Crossroads. Start with a wake-up call: Richard Battle lays out why America stands at a crossroads—can free enterprise and liberty survive in a world drifting toward socialism? Hear powerful arguments for economic freedom, plus a candid look at inflation, government overreach, and immigration. John tackles Colorado's political storm, revealing why divided conservatives could see their state slip away for good. Sunny Kutcher of Young Americans Against Socialism brings the heat, exposing the rapid rise of socialist ideas and the high stakes for government accountability. Dive into Fauci's testimony, pandemic fallout, free speech battles, and border clashes—plus, why the next Colorado election could change everything. If you care about America's future, you can't afford to miss this. Timestamps 1:09 — Richard Battle — https://RichardBattle.com 30:37 — Sunny Kutcher — https://yaas.org Hour 3 COVID Secrets, AI Showdown, and Colorado's Tech Future Hang in the Balance Uncover the untold story behind COVID lockdowns as Michael Pack reveals what went into the making of ‘Lockdown Dissidents.' Go behind the scenes with Fauci's diary, the fallout of school closures, and the fight for civil liberties. John Rush pulls back the curtain on the backlash he faced for challenging the status quo—proving why questioning authority is more important than ever. Then, shift gears as Scott Garliss breaks down the high-stakes world of Wall Street and artificial intelligence—revealing how today's tech battles could decide America's financial future. John fires back at short-sighted tech critics, champions AI innovation, and explains why your vote could shape the next era of American leadership. Timestamps 1:07 — Michael Pack — https://palladiumpictures.com/ 28:34 — Scott Garliss — https://www.bentpinecapital.com/
Join the Conversation at 303-477-5600 or text to 307-200-8222. Monday-Friday, 3 pm-6 pm MT. https://RushToReason.com Hour 1 Stage 4 Cancer, Heart Disease, and the Health Choices That Could Change Everything. Kick off Health and Wellness Wednesday with John Rush as he dissects new revelations about Anthony Fauci and the unresolved mysteries of the COVID era. Then, plunge into two gripping, real-life stories of defying the odds—where hope, healing, and prevention take center stage. What if stage 4 cancer isn't the end—but a new beginning? Emma Victoria Johnson reveals how she turned a devastating diagnosis into a story of hope, discovering lifesaving breakthroughs at Oasis of Hope. Hear how bold lifestyle changes, nutrition, and immune health fueled her fight for recovery. Next, Wayne Elliott recounts surviving a heart attack at just 35. Discover the unconventional choices he credits with transforming his life—and what most people overlook about heart health. Obesity, statins, Alzheimer's, toxins, and the daily habits that could change your future—don't miss these life-altering insights. John wraps up with a bold question: Is our addiction to convenience silently sabotaging our health? This hour is packed with inspiring stories, frank conversations, and eye-opening ideas that might just make you rethink your everyday choices. Timestamps 11:46 — Emma Victoria Johnson — https://www.oasisofhope.com 30:38 — Wayne Elliott — https://straussnaturals.com HOUR 2 Freedom, Socialism, Fauci, and Colorado's Political Crossroads. Start with a wake-up call: Richard Battle lays out why America stands at a crossroads—can free enterprise and liberty survive in a world drifting toward socialism? Hear powerful arguments for economic freedom, plus a candid look at inflation, government overreach, and immigration. John tackles Colorado's political storm, revealing why divided conservatives could see their state slip away for good. Sunny Kutcher of Young Americans Against Socialism brings the heat, exposing the rapid rise of socialist ideas and the high stakes for government accountability. Dive into Fauci's testimony, pandemic fallout, free speech battles, and border clashes—plus, why the next Colorado election could change everything. If you care about America's future, you can't afford to miss this. Timestamps 1:09 — Richard Battle — https://RichardBattle.com 30:37 — Sunny Kutcher — https://yaas.org Hour 3 COVID Secrets, AI Showdown, and Colorado's Tech Future Hang in the Balance Uncover the untold story behind COVID lockdowns as Michael Pack reveals what went into the making of ‘Lockdown Dissidents.' Go behind the scenes with Fauci's diary, the fallout of school closures, and the fight for civil liberties. John Rush pulls back the curtain on the backlash he faced for challenging the status quo—proving why questioning authority is more important than ever. Then, shift gears as Scott Garliss breaks down the high-stakes world of Wall Street and artificial intelligence—revealing how today's tech battles could decide America's financial future. John fires back at short-sighted tech critics, champions AI innovation, and explains why your vote could shape the next era of American leadership. Timestamps 1:07 — Michael Pack — https://palladiumpictures.com/ 28:34 — Scott Garliss — https://www.bentpinecapital.com/
Good morning from Pharma Daily: the podcast that brings you the most important developments in the pharmaceutical and biotech world. Today, we delve into a series of events that underscore the dynamic nature of these industries, characterized by scientific advancements, strategic partnerships, and regulatory milestones. Johnson & Johnson has made headlines with its substantial $785 million upfront payment to Sail BioMed for an in vivo CAR-T cell therapy deal. This agreement includes an option for Johnson & Johnson to acquire Sail BioMed for $2.58 billion, underscoring the sustained interest in cell therapies, particularly for autoimmune diseases. In vivo CAR-T therapies represent a significant leap forward by modifying T cells directly within the patient's body. This method offers potential advantages over traditional ex vivo techniques by simplifying the manufacturing process and potentially reducing both costs and time to treatment. Such transactions highlight Johnson & Johnson's commitment to expanding its cell therapy portfolio, which could significantly enhance patient care by making advanced treatments more accessible. Eli Lilly and Resilience have announced a significant $750 million investment aimed at boosting the production of diabetes and obesity medications in the United States. This move comes as a response to the global rise in these conditions, necessitating increased production capacities to meet growing demand. The focus on injectable drug devices emphasizes efforts to improve drug delivery systems, ultimately enhancing patient compliance and therapeutic outcomes. Sanofi's financial outlook for 2026 is promising, driven by robust sales of Dupixent, which exceeded €5 billion in quarterly sales. Dupixent, a monoclonal antibody used for treating atopic dermatitis and other autoimmune conditions, has been a significant revenue driver for Sanofi. The success of Dupixent reflects its effectiveness and strong market adoption, highlighting the potential of monoclonal antibodies as cornerstones of modern pharmacotherapy, particularly for chronic inflammatory diseases. Regeneron and Sanofi's Dupixent continues performing strongly with $6 billion in sales during Q2 2026—marking its largest quarterly revenue since the pandemic began—illustrating robust demand across various indications within both companies' portfolios. On the regulatory front, Alfasigma's Linerixibat (Lynavoy) has received a positive opinion from the CHMP for treating cholestatic pruritus in primary biliary cholangitis following successful Phase 3 trials. As an IBAT inhibitor targeting bile acid metabolism pathways, Lynavoy introduces a novel therapeutic approach for managing symptoms associated with this autoimmune liver disease. Meanwhile, ImmunityBio's Anktiva has gained marketing authorization in the UAE for non-muscle invasive bladder cancer and metastatic non-small cell lung cancer. Anktiva, an IL-15 cytokine-based protein therapy, exemplifies the growing interest in harnessing immune system modulators for cancer treatment. Takeda's recent decision to discontinue its nanoparticle therapy (TAK-101) for celiac disease highlights the inherent challenges in developing new therapies for autoimmune disorders. The disappointing Phase 2 results suggest that achieving immune tolerance to dietary gluten remains a significant scientific hurdle. From a strategic perspective, Sanofi's CEO has emphasized stricter go/no-go decisions during Phase 3 clinical trials amid pipeline cuts and significant impairment losses. This approach could lead to more efficient resource allocation and potentially higher success rates for late-stage drug candidates. The industry is witnessing significant transformations through strategic shifts driven by executives like Sanofi's new CEO Belen Garijo. Her vision includes reversing recent challenges faced by Sanofi by capitalizing on its strengths while addressing setbacks such as discontinuing certain late-stage clinical programs like the joint venture with Regeneron on the IL-33 candidate itepekimab. This strategic pivot mirrors broader industry trends toward optimizing late-stage pipelines to enhance competitive positioning and drive future growth. Advancements in AI-powered drug discovery continue gaining momentum through collaborations like those between GSK and Relation Therapeutics, alongside Causaly and Sage. These partnerships aim to leverage AI and machine learning technologies to accelerate drug discovery processes by integrating vast amounts of scientific literature into data analytics platforms. GlaxoSmithKline's $110 million deal with an AI biotech firm further signals increased integration between artificial intelligence technologies and pharmaceutical research efforts aimed at enhancing dataset quality thereby accelerating innovation throughout drug discovery processes. Bristol Myers Squibb faces further delays regarding its Alzheimer's psychosis treatment Cobenfy—a postponement reflecting ongoing complexities related to neurological drug development which requires overcoming high scientific hurdles alongside regulatory scrutiny. Alnylam Pharmaceuticals recently experienced a 29% drop in stock value following disappointing sales of Amvuttra and a downward revision of its ATTR franchise outlook for 2026. Such fluctuations highlight volatility within biotech investments when market expectations are not met. These collective developments reveal significant trends shaping today's pharmaceutical landscape: strategic pipeline optimization efforts alongside robust investment initiatives targeting high-demand therapeutic areas—all while leveraging technological advancements like AI integration aimed at improving R&D efficiency ultimately impacting patient care worldwide through innovative therapies addressing unmet medical needs globally.Support the show
On this episode of My Life Now, Chris Buscher sits down with educator and thriller author John Infortunio.John's novels draw from deeply personal experiences, including losing his father to Alzheimer's and working inside the world of an elite prep school. In this conversation, he shares how those experiences shaped Destroyed by the Events of the Day and Today Was Tomorrow, two thrillers that explore grief, betrayal, family secrets, institutional pressure, and redemption.The discussion also looks at the emotional line between autobiography and imagination, the power of unreliable narrators, and why some of the most gripping suspense comes from pain that feels real.If you enjoy emotionally layered thrillers, family drama, and conversations about how real life becomes fiction, this episode is for you.
https://www.drsharnael.com/ tell me about your new book what inspired it what is iboga how is it different the ibogaine how has it helped people is it safe ? what do you have coming up ? 1. Why is it important to consciously connect with Nature and recognize that She is a living sentient being? 2. What are the health benefits of being in a felt communion with Nature? 3. A few highlights from my own journey into Nature Reunion 4. Some easy but powerful practices for Nature reconnection 5. Our body as part of Nature—treating ourselves with mindful self-compassion and respect. 6. Coming Home to Nature means being deeply aware of, and connected to, the wisdom and healing power of Mother Earth and our own bodies. 7. My book, both kindle and paper back will be released on August 1st. The kindle e-book version is available now. What if the roots of suffering are deeper than we'vebeen taught? Is there hope when hope for the hopeless? When life fractured in ways she could notintellectually solve, Dr. Sharnael — naturopathic physician and consciousnessteacher — was called beyond logic, beyond theology, beyond science — intodirect encounter. Enter Iboga. Often referred to as “Grandfather Iboga” and known asthe “Mount Everest of plant medicines,” this“The Truth Hunter,” African root functions as a powerful neurological andpsychological interrupter, disrupting entrenched patterns of illusion,compulsion, and genetic survival programming. In this deeply personal journey, Dr. Sharnael shareshow one of the most intense and misunderstood plant medicines on earth became amirror — illuminating unresolved grief and the unconscious patterns shapingidentity, while guiding her from darkness and sorrow into renewed hope,courage, love, and joy. At a time when suicide rates remain high and opioidaddiction devastates families worldwide, Iboga has drawn attention for itsunique interaction with opioid receptors and its growing exploration inaddiction recovery research. It is also being studied for its potential relevance indepression, PTSD, traumatic brain injury, multiple sclerosis, Alzheimer's,Parkinson's disease, Lyme-related neurological complications, and other complexnervous system disorders. Traditionally, the root bark has also been examinedfor antimicrobial and antiparasitic properties. Part personal journey, part clinical guide, GrandfatherIboga serves readers seeking Truth, transformation, and understanding. Written by a doctor who became the patient, this bookis for anyone navigating loss, addiction, neurological complexity, and foranyone seeking Divine Truth where conventional paths have fallen short I almost didn't write these books. It would have beeneasier to stay quiet. Easier not to speak publicly about grief. Trauma. Plantmedicine. Consciousness. Easier to protect my reputation than enterconversations that are complex, controversial, and often misunderstood. But silence felt dishonest. And some stories are meant to be told. Today, I am honored to officially announce the releaseof two deeply personal and professional works: The Science of Miracles Workbook and Grandfather Iboga – A Personal Journey Through Grief,Trauma Healing, and Soul Transformation These are not just books. They are lived experience. Together, these two books represent the bridge I havealways stood on — science and spirit, clinical understanding and consciousness,measurable biology and Divine design. There were moments I nearly stayed silent. But if even one person finds hope in these pages… itwas worth it. Presales are now open. You can order both books here:https://www.drsharnael.com/shop The Science of Miracles Workbook This workbook was born from years of studyingconsciousness, neuroscience, biofeedback, and the unseen laws that shape ourphysical reality.
Ask most people what a brain chip does and they will tell you it reads your mind. Dr. Michael Lawton implants these devices, and he says that is not what comes off them. He is President and CEO of Barrow Neurological Institute in Phoenix, the hospital where Neuralink's first human implant was performed, and he has completed more than 10,000 brain operations and clipped around 5,500 aneurysms. Louisa sat down with him inside Barrow to find out what the electrodes actually pick up, how far the technology has come, and where it stops. He walks through the surgery itself. The device goes into the hand knob, one small lobule of the motor cortex, where 64 electrodes have already become 108. The threads carrying them are about a tenth the thickness of a hair, so a robot inserts them while avoiding every arteriole on the surface. You'll hear what Nolan Arbaugh, Neuralink's first patient, can now do with a cursor at world record speed, and why Lawton can't keep up with him in a head to head. Then the correction. The data coming off these electrodes is a train of spikes, the same electrical language every neuron in your head is already using, and decoding it tells you whether a person meant to move a cursor left or right. Reading an emotion, or what someone thinks of you, is nowhere close. The second half turns to the brain Lawton has spent 29 years operating inside. He describes cooling a patient to 15 degrees Celsius and stopping their circulation completely, which shrivels a giant aneurysm like a raisin and opens a short window to repair it. He explains why the hardest cases will still need a pair of human hands, and what he tells trainees who think their craft is disappearing. On brain aging he is direct about what works. He predicts alcohol will be viewed in 20 years the way cigarettes were viewed in the 60s, he takes zero supplements and no peptides, and he says exactly what he can and cannot see when he looks at a living brain on the table. You'll also hear about Barrow's Mindgenuity Labs and its six mysteries of the mind, why he ranks movement as the first one to fall and consciousness as the one that may never be solved, what he believes consciousness physically is inside 86 billion neurons, and the ground underneath all of it. His sister died of a brain tumor. Louisa's father had a stroke in 2019. Both of them have watched this from the other side of the table. *Reduce your risk of Alzheimer's with my science-backed protocol for women 30+:* https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ *TOPICS DISCUSSED* 00:00 Intro: The Brain Surgeon at Neuralink's First Hospital 00:39 The Guy Who Does the Cases Nobody Else Wants 02:17 A Day in the Life: 5:30am Starts and Three Surgeries 03:20 "Game Tape": Reviewing Every Operation Like an Athlete 04:24 The Surgeon Athlete and Why Surgery Is a Physical Skill 05:32 Fifty Years From Now: What Happens to Neurosurgery 06:11 The ROSA Robot and Mapping a Seizure Focus 08:16 Deep Brain Stimulation and Hitting an Exact Target 08:52 Will We All Be Operated On by Robots? 10:02 The Brain AVM: The One Case a Robot Can't Take 11:18 Why Bleeding Breaks a Robot: The Waymo Problem 13:15 What a Brain-Computer Interface Actually Does 14:49 The Hand Knob: 108 Electrodes in One Small Spot 15:50 Cursor Control at World Record Speed 16:31 Inside the Implant: Threads a Tenth the Width of a Hair 17:27 "No, the Chip Cannot Read Your Thoughts" 17:58 What the Device Really Reads: A Train of Spikes 19:18 From Movement to Sensation: What Comes Next 19:48 Why Restoring Sight Is So Much Harder 20:58 The 1943 Paper That Predicted All of This 22:37 Elon, Telepathy, and What's Actually Possible 23:00 Boosting Creativity and Intelligence in 50 Years 25:10 "When I Retire, We'll Be Treating Depression and Addiction" 26:04 Alzheimer's: Light Therapy and the Blood-Brain Barrier 27:11 Treating the Disease vs Preventing It 28:25 10,000 Operations: How He Feels About Robots Taking Over 29:54 Neuroplasticity: How Nolan's Brain Learned the Device 31:34 What Actually Changes at the Neuron Level 32:04 Patient Two and the Robotic Arm 32:42 5,500 Aneurysms: The Cases That Stay With Him 33:16 Cardiac Standstill: Cooling a Brain to 15 Degrees 35:46 What Separates a Great Surgeon From an Average One 36:17 Traits of Greatness: The Formula Nobody Has Cracked 37:21 The Phone Call in the Middle of a 16-Hour Surgery 39:35 "I Must Have Been Born for This" 41:26 Can You Tell How Old a Brain Is Just by Looking? 43:12 Why Alzheimer's Is Invisible in a Living Brain 44:14 What a Neurosurgeon Does to Protect His Own Brain 44:40 "Alcohol Will Be Viewed Like Cigarettes in the 60s" 45:13 Peptides, Injectables, and Zero Supplements 46:52 The Last Generation to Operate With Open Hands 48:10 How Louisa Found Him on Twitter in 2021 48:53 The Six Mysteries of the Mind 49:14 Which One Gets Solved First, and Which May Never 50:03 Is Consciousness in the Tissue? 51:39 Memory: The Circuitry We Still Can't Explain 53:18 Why Consciousness Is Harder Than Memory 55:12 Louisa's Father's Stroke 56:02 Advice for Anyone Watching a Parent Decline 56:21 His Sister's Brain Tumor and How He Carries It 57:38 A World Where Stroke Is an Outpatient Repair 58:40 Forty Years On, Finally at the Dawn _______ *Thank you to our sponsors* Timeline (Mitopure): https://timeline.com/neuro Mitopure now starts at $79 Ogee: https://ogee.com Use code XXXXX for a discount on the Crystal Contour Collection Kion (Kion Aminos): https://getkion.com/neuro Use code XXXXX for a discount Function Health: https://functionhealth.com/LouisaNicola Use code NEURO25 for a $25 credit _______ I'm Louisa Nicola - clinical neurophysiologist - Alzheimer's prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer's risk - and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices
When Sarah Leavitt's mother was diagnosed with Alzheimer's disease, she began documenting everything she could through drawings and writing. Those records became Tangles, her acclaimed 2010 graphic memoir, which was the first graphic narrative to be named a finalist for the Writers' Trust Prize for Nonfiction. Now, more than 15 years later, Tangles has been adapted into a film starring Julia Louis-Dreyfus (Seinfeld, Veep), Bryan Cranston (Breaking Bad), Abbi Jacobson (Broad City) and Wanda Sykes (The New Adventures of Old Christine). Sarah co-wrote the screenplay, and the film premiered at this year's Cannes Film Festival, where it received a lengthy standing ovation. Q guest host Angeline Tetteh-Wayoe caught up with Sarah to talk about it.
A test diagnosing Alzheimer’s up to 20 years before symptoms appear, Aussies face new petrol warnings as the Iran war spreads to the Red Sea. Plus, Labor MP Luke Gosling charged with assault.See omnystudio.com/listener for privacy information.
In this episode of The Daily T, Tim Stanley and Poppy Coburn discuss the state of free speech in the UK following Allison Pearson's victory against Essex Police's crime commissioner and The Met Police confirming it will take no further action against Zack Polanski for sharing a post that appeared to threaten Nigel Farage. Is there a double-standard in the way different views are policed?Tim Stanley and Poppy Coburn also speak to ex-ITV This Morning editor Martin Frizell about his wife Fiona Phillips' Alzheimer's diagnosis, and what he wants to see from Andy Burnham's social care reforms.We want to hear from you! Email us at thedailyt@telegraph.co.uk or find @dailytpodcast on TikTok, Instagram and X► Sign up to our most popular newsletter, From the Editor. Look forward to receiving free-thinking comment and the day's biggest stories, every morning. telegraph.co.uk/fromtheeditorThe Telegraph is the Publisher Podcast Awards' Podcast Publisher of the Year 2026Studio Operator: Meghan SearleProducers: Emma Williams, Georgia Coan and James KeeganVideo Producer: Will WaltersSocial Producer: Nada AggourExecutive Producer: Charlotte SeligmanEditor: Camilla TomineyHighlightsTim and Poppy discuss free speech following Allison Pearson's victory and the Met Police taking no further action against Zack PolanskiMartin Frizell on his wife Fiona Phillips' Alzheimer's condition and Andy Burnham's social care reforms Hosted on Acast. See acast.com/privacy for more information.
You made the hardest decision of your life and moved your loved one with dementia into memory care. Then you waited for the relief you were promised. It never fully came. You still feel completely wiped out after visits, even good ones, and no one has explained why. Placement changes the physical work of caregiving, but it does not turn off your nervous system, your grief, or the recovery your body still needs. In this episode I break down the three real reasons your exhaustion continues after a memory care placement, and what to actually do about it. If you'd like to see this episode on video, you can hop on over to my YouTube channel here. The Dementia Care Toolkit is officially available for pre-order. This book was written for the real-life moments of dementia caregiving, the moments when you're overwhelmed, unsure what to do, and need something practical to reach for. ➡️ Preorder the Dementia Care Toolkit Here: https://careblazers.com/toolkit ⏱ CHAPTERS 0:00 - Why the exhaustion hits even after a good visit 1:32 - The misconception that memory care makes things easier 2:34 - Why your nervous system stays on high alert 5:05 - The grief of losing someone who is still alive 8:59 - Three ways to support your own recovery → Join the Care Collective: https://tinyurl.com/podcast-cc → Get free weekly tools and tips in my newsletter, The Dementia Dose: https://tinyurl.com/dementiadose-podcast --- Hi, I'm Dr. Natali Edmonds, a board-certified geropsychologist specializing in dementia care. Whether your loved one has Alzheimer's, frontotemporal, Lewy body, vascular, or mixed dementia, we believe that to create a dementia-friendly world, we must first create a caregiver-friendly world. This content is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for medical guidance.
HEADLINES: Confirming an Alzheimer's diagnosis could soon be as simple as a blood test. Australia's second-largest telco is facing legal action over a major network failure that caused a widespread triple-zero outage. Australia’s online watchdog - launches legal action against a popular messaging app for failing to remove terror related content. Bird flu cases have been detected in a fifth state, prompting warnings of a national wildlife emergency. A new edition of an iconic The Beatles' is set to be released. GET IN TOUCHGot a story, news tip-off, feedback or dilemma?Send us a voice note or email us at thequicky@mamamia.com.au SUBSCRIBER GIVEAWAY: The Out Loud hosts have handpicked their all-time favourite reads and one subscriber is winning the entire 12-book stack. Subscribe to Mamamia here to be automatically entered. Already a subscriber? Don't sweat it, you're already in. T&Cs apply. CREDITSHost: Talissa Bazaz Audio Producer: Scott Stronach Group Executive Producer: Charlotte Mortlock, Talissa Bazaz & Georgie Page Check out The Quicky Instagram here and our TikTok here Discover more Mamamia podcasts here Did you know some of our shows are now in video on the Apple Podcast app? Make sure your phone is up to date and check it out here! Mamamia acknowledges the traditional owners of the land on which we have recorded this podcast.Become a Mamamia subscriber: https://www.mamamia.com.au/subscribeSee omnystudio.com/listener for privacy information.
Good morning from Pharma Daily: the podcast that brings you the most important developments in the pharmaceutical and biotech world. Biogen has made a significant acquisition by purchasing Apellis Pharmaceuticals, a move expected to boost its 2026 revenue guidance with promising growth prospects. This strategic acquisition, along with strong sales from new drugs, enhances Biogen's position in the competitive market for neurological disorders. By integrating Apellis' offerings, Biogen is poised to strengthen its portfolio, particularly in areas of unmet medical need. On the regulatory front, AbbVie has achieved a milestone with its drug Rinvoq (upadacitinib), which has received dual approvals from the European Union for treating non-segmental vitiligo and severe alopecia areata. These approvals were based on successful Phase 3 data, underscoring Rinvoq's efficacy as a JAK inhibitor in tackling autoimmune conditions. This development not only highlights AbbVie's commitment to expanding its therapeutic portfolio but also positions upadacitinib as a potential mainstay treatment for dermatological autoimmune diseases. AstraZeneca Pharma India has secured approval from the Central Drugs Standard Control Organization for Enhertu (trastuzumab deruxtecan) in the neoadjuvant setting for HER2-positive early breast cancer. This approval marks a significant advancement in personalized cancer therapy, offering new hope for patients with this aggressive form of breast cancer. In terms of industry collaborations, the landscape is witnessing numerous partnerships and strategic alliances that are driving innovation forward. Skyverna Therapeutics and ElevateBio have entered a five-year clinical and commercial supply agreement for autoimmune CAR-T therapy, reflecting the growing interest in cell therapies for rare diseases. Meanwhile, Vertex Pharmaceuticals and AbCellera have joined forces to accelerate drug discovery in autoimmune T-cell engagement, supported by a $28 million upfront investment. These collaborations emphasize the importance of combining expertise and resources to advance complex therapeutic solutions. The integration of artificial intelligence in drug development continues to gain momentum. Evinova and Merck KGaA's strategic collaboration aims to leverage AI and machine learning to enhance clinical trials' efficiency, potentially ushering in a new era of precision medicine. Such partnerships highlight the transformative potential of AI in streamlining research and development processes. In funding news, Core Biomedicine has secured $21 million in Series A financing to advance its precision oncology therapeutics. Enlivex's substantial $400 million private placement aims at advancing prediction markets treasury and Allocetra immunotherapy, further accentuating the focus on personalized medicine targeting specific cancer pathways. Clinical trials have also delivered promising results. ProMIS Neurosciences reported positive interim safety and biomarker data from its Phase 1b study of PMN310 for Alzheimer's disease. This monoclonal antibody targets amyloid-beta oligomers implicated in Alzheimer's pathology, offering hope for patients with this debilitating disorder. Mergers and acquisitions remain active, exemplified by Caldera Therapeutics' reverse merger with Synlogic alongside $278 million in financing to advance its bispecific antibody for inflammatory bowel disease. This move reflects a broader trend toward consolidating resources to tackle complex autoimmune conditions. Eli Lilly's ascent to the top of Norstella's pipeline-to-patient productivity index is noteworthy, driven by successful launch strategies and rapid development cycles. This achievement underscores Eli Lilly's effective alignment of R&D efforts with market needs, particularly in areas such as GLP-1 receptor agonists that have transformed diabetes care. Teva Pharmaceuticals is demonstrating resilience through its innovative medicines portfolio amidst declining generic sales. The unexpected surge in Ajovy sales highlights Teva's pivot toward high-value branded drugs amidst competitive pressures. Novo Nordisk faces legal challenges as it navigates allegations regarding Cagrisema's Phase 3 study protocol changes. Legal scrutiny around transparency in clinical trial disclosures continues to highlight the importance of ethical practices and investor trust. Collectively, these developments illustrate a vibrant yet challenging environment where scientific advancements in immunotherapy and targeted treatments intersect with strategic business alignments focused on sustainable growth. As these trends unfold, they promise more effective treatments for complex diseases while companies adapt to an evolving market environment demanding agility and foresight. As always, stay tuned to Pharma Daily for more insights into how these transformations continue to shape the future trajectory of drug development and healthcare delivery globally.Support the show
Law enforcement shooting death in Forest County found to be justified, more than 7 million Americans living with Alzheimer's disease, judge rules those who voted early can't get new ballots
Carrie & Tommy Catchup - Hit Network - Carrie Bickmore and Tommy Little
Today brought some very interesting and thought provoking information about Alzheimer's as well as some good ol' Katy Perry news AND a chat with the one and only Lizzy Hoo!!!Subscribe on LiSTNR: https://play.listnr.com/podcasts/carrie-and-tommySee omnystudio.com/listener for privacy information.
Gray divorce hit 36%, Danny Glover went public with his Alzheimer's diagnosis, BPC-157 quietly became legal again, a new bill takes aim at menopause discrimination at work, and celebrities are lining up to undo their own plastic surgery. Chalene Johnson breaks down why this is all happening at once. Chalene digs into why Kylie Jenner, Simon Cowell, and Kim Zolciak are all now saying they regret work they once defended, why Emily Simpson and Angie Katsanevas are living out the gray divorce numbers in real time, and why lawmakers like Debbie Dingell are stepping in on menopause discrimination at work. Topics discussed: gray divorce, Real Housewives of Orange County, Emily Simpson, Real Housewives of Salt Lake City, Angie Katsanevas, Shawn Trujillo, Danny Glover, Alzheimer's, magnesium, BPC-157, Botched Presents: Plastic Surgery Rewind, Kylie Jenner, Nicki Minaj, Simon Cowell, Kim Zolciak, Menopausal Workers' Fairness Act, Debbie Dingell Go Beyond The Podcast Join Chalene on her private podcast
Living with chronic illness can feel like collecting diagnoses without getting real answers. Symptoms are treated one at a time, but the underlying causes can easily be missed. What if asking a different question is the first step toward feeling better? In this episode, I'm joined by Dr. Richard Horowitz, an internationally recognized Lyme disease expert and author of the new book Ending Chronic Illness. After caring for thousands of patients over more than four decades, he explains why many seemingly unrelated conditions share common underlying drivers—and why thinking like a medical detective may help uncover them. We discuss: Why treating the diagnosis isn't always the same as treating the problem—and how to start looking deeper How hidden infections, environmental toxins, gut health, and other overlooked factors can quietly drive chronic illness What new research may reveal about the links between infection, inflammation, and brain health How to begin uncovering what's really driving persistent symptoms Our bodies are constantly communicating with us. The challenge isn't that they're silent—it's that we haven't always known how to listen. Sometimes finding better answers begins with asking different questions. Continue Exploring If you'd like to explore Dr. Horowitz's work further, here are two great places to start: Take his Symptom Assessment Quiz to better understand what may be contributing to your symptoms. Subscribe to his Medical Detective Substack ****for ongoing insights into chronic illness, Lyme disease, and root-cause medicine. Interested in getting tested? Many of the lab tests discussed in this episode are available through Function, making it easier to get a more comprehensive picture of your health. View Show Notes From This Episode Sign up for Dr. Hyman's Brainshaping Academy to learn how to nourish the biological systems that support your mental, emotional, and cognitive health https://drhyman.com/products/brainshaping?utm_source=dr_hyman_show&utm_medium=newsletter&utm_campaign=may_27&utm_content=link Get Free Weekly Health Tips from Dr. Hymanhttps://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman's Weekly Longevity Journalhttps://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Healthhttps://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Resultshttps://drhyman.com/pages/hyman-hive This episode is brought to you by Timeline, Cozy Earth, Seatopia, Perfect Amino, BON CHARGE, and Made In. Support healthy aging and get up to 20% off when you subscribe on top of the new starting price of $79 at timeline.com/drhyman. Upgrade your sleep setup with cozyearth.com and enjoy 20% off with code HYMAN. Find a cleaner source of seafood. Check out seatopia.fish and use code HYMAN for free shipping on your first order. Help fill protein gaps at bodyhealth.com and use code HYMAN20 for 20% off. Explore red light products at boncharge.com/hyman and enjoy 15% off with code HYMAN. Explore kitchen essentials at madeincookware.com and save 10% off your first order with code HYMAN-HIVE. (0:00) Infections and toxins as root causes of chronic illness; Dr. Horowitz's background and journey to functional medicine (5:37) Discovering and treating various infections, toxins, and Dr. Hyman's personal health story (9:16) Root causes of chronic disease, inflammation, and testing for infections and toxins (15:11) Sponsor: Seatopia and PerfectAmino (16:42) Importance of diet, addressing multiple health factors, and autoimmune misdiagnosis (19:26) Role of infections, toxins, microbiome, and leaky gut in autoimmune diseases and inflammation (21:06) Treating underlying causes and neuroinflammation in chronic diseases (24:37) Nutritional deficiencies, COVID-19, and the importance of sleep in chronic illness management (30:19) Plant medicines, supplements, and dapsone in treating neuroinflammation, Lyme, and Alzheimer's (41:30) Use of methylene blue in treatment protocols (44:56) Sponsor: Bon Charge (45:58) Sponsor: Made In (46:43) Evolution of treatment protocols and six principal causes of inflammation (50:18) Importance of adrenal function and hormone treatment in chronic illness (52:17) Differential diagnosis vs. root cause analysis and root cause testing (56:38) Horowitz's questionnaire and protocols for treating chronic infections (58:39) Addressing mold-related health issues and Dr. Hyman's personal experience (1:01:01) Mold testing, detoxification, and controversies in treatment (1:07:47) Insurance challenges and HHS innovation grant for chronic illness research (1:09:04) Importance of root cause medicine and Mark Hyman's upcoming book on longevity (1:11:56) Personalized medicine, reversing Alzheimer's biomarkers, and research funding priorities (1:15:02) Influence of Buddhist principles and personal experiences with chronic illness (1:16:01) Hope for patients, resources for learning, and closing remarks
Dr. Joy sits down with neuropsychologist Dr. Tanisha Hill-Jarrett, assistant professor at UCSF's Memory and Aging Center, to talk through what brain health means, why it's broader than mental health alone, and the daily habits that support it: cardiovascular exercise, a heart-healthy diet, stress management, social connection, and quality sleep. They dig into what our phones are doing to us. Dr. Hill-Jarrett breaks down how short-form video triggers a bigger dopamine response than a typical reward, why the unpredictability of a feed keeps us scrolling, and what that means for sleep, attention span, and memory. She shares her own strategies, including separate personal and professional Instagram accounts and the Pomodoro method for resetting focus without reaching for a screen. The conversation turns to her research on Black women and Alzheimer's disease. Black Americans face 1.5 to 2 times the risk of white Americans, and Black women carry the highest projected prevalence of any group, a gap that shows up even among women who are upwardly mobile, largely tied to the neighborhoods they live in. Dr. Hill-Jarrett also unpacks weathering, the term coined by Arlene Geronimus for the accelerated biological aging that Black women experience, and points to research showing Black women's telomeres suggest they are roughly seven and a half years biologically older than white women at the same age. She closes with her current work on Afrofuturism and hopefulness, including a 10-week workshop where participants imagined a future free of time scarcity and reported feeling more hopeful about shaping what comes next. Her advice for anyone worried it's too late to protect their brain: it never is. About the Podcast The Therapy for Black Girls Podcast is a weekly conversation with Dr. Joy Harden Bradford, a licensed Psychologist in Atlanta, Georgia, about all things mental health, personal development, and all the small decisions we can make to become the best possible versions of ourselves. Resources & Announcements Want to reflect on this conversation in community? Join us inside our Patreon community where we’re unpacking this episode together. You can now catch episodes of the Therapy for Black Girls podcast on YouTube. Be sure to subscribe to get new episodes every week. Did you know you can leave us a voice note with your questions for the podcast? If you have a question you'd like some feedback on, topics you'd like to hear covered, or want to suggest movies or books for us to review, drop us a message at memo.fm/therapyforblackgirls and let us know what’s on your mind. We just might share it on the podcast. Grab your copy of Sisterhood Heals. Where to Find Our Guest Website Instagram LinkedIn Stay Connected Is there a topic you'd like covered on the podcast? Submit it at therapyforblackgirls.com/mailbox. If you're looking for a therapist in your area, check out the directory at https://www.therapyforblackgirls.com/directory. Grab your copy of our guided affirmation and other TBG Merch at therapyforblackgirls.com/shop. The hashtag for the podcast is #TBGinSession. Make sure to follow us on social media: Instagram: @therapyforblackgirls Facebook: @therapyforblackgirls Our Production Team Executive Producers: Dennison Bradford & Gabrielle Collins Director of Podcast & Digital Content: Ellice Ellis Producer: Ndeye Thioubou Production Assistant: Bria MosleySee omnystudio.com/listener for privacy information.
A tiny molecule produced inside your body may play a major role in how well you circulate blood, manage inflammation, exercise, and age. In this episode of Sharkpreneur, Seth Greene interviews Nathan S. Bryan, Ph.D., Founder, Chairman, and CEO of Bryan Therapeutics, Inc., who explains nitric oxide's role in blood-vessel function, tissue oxygenation, inflammation, metabolism, and cellular energy, and shares his view on everyday habits that can affect the body's natural production. He also discusses the oral microbiome, dietary considerations, lifestyle practices, consumer education, and the research-based standards he believes people should use when evaluating nitric oxide-related products. Key Takeaways:→ Nitric oxide helps regulate blood flow, oxygen delivery, inflammation, metabolism, and cellular signaling. → Oral-care habits may affect the oral microbiome, which helps metabolize dietary nitrate.→ Green vegetables and beets may contain dietary nitrate.→ Product claims should be supported by scientific and clinical data. → Lifestyle habits influence nitric oxide production. Dr. Nathan S. Bryan earned his undergraduate Bachelor of Science degree in Biochemistry from the University of Texas at Austin and his doctoral degree from Louisiana State University School of Medicine in Shreveport, where he was the recipient of the Dean's Award for Excellence in Research. He pursued his postdoctoral training as a Kirschstein Fellow at Boston University School of Medicine's Whitaker Cardiovascular Institute. After a two-year post-doctoral fellowship, in 2006, Dr. Bryan was recruited to join the faculty at the University of Texas Health Science Center at Houston by Ferid Murad, M.D., Ph.D., 1998 Nobel Laureate in Medicine or Physiology. Dr. Bryan has been involved in nitric oxide research for the past 25 years and has made many seminal discoveries in the field, has dozens of issued patents, and has published more than 100 peer-reviewed scientific articles in some of the top science and medical journals. Dr. Bryan is a best-selling author and successful entrepreneur who has built a billion-dollar enterprise value portfolio of companies. Dr. Bryan is one of the most successful inventors and top revenue producers in the history of the University of Texas Health Sciences Center at Houston. He is currently the Founder, Chairman, and CEO of Bryan Therapeutics, Inc., a privately held, clinical-stage biotechnology company actively engaged in the discovery and development of nitric oxide-based therapies. BTI has active drug development programs in heart disease, Alzheimers' Disease, and topical drugs for diabetic ulcers and non-healing wounds. Dr. Bryan's consumer line of nitric oxide products is among the most innovative and successful on the market. Dr. Bryan is an international leader in molecular medicine and nitric oxide biochemistry. Connect With Nathan:Website: https://n1o1.com/https://bryantherapeutics.com/ Instagram: https://www.instagram.com/drnathansbryan X: https://x.com/drnitric LinkedIn: https://www.linkedin.com/in/drnathansbryan/ YouTube: https://www.youtube.com/@drnathansbryannitricoxide
Generosity can begin with a simple gift, but when it becomes a family rhythm, its impact can last for generations. Most parents want their children to grow into generous adults—people who see what God has entrusted to them as something to be stewarded for His purposes and the good of others. But generosity rarely develops by accident. It is cultivated over time through example, experience, and intentional practice. Sharon Epps, President of Kingdom Advisors and Co-Founder of Women Doing Well, joins the show today to encourage families to begin teaching generosity early and continue nurturing it through every stage of life. The goal is not simply to raise children who give money, but to help them discover the joy of living generously with everything God has provided. Start by Modeling Generosity Young children may not understand much about money yet, but they are always watching. That makes the early years an ideal time to model generosity through simple, tangible experiences. Parents might take their children grocery shopping for items to donate to a local food pantry, allowing them to choose the food and deliver it. The lesson is simple: We have something we can share, and together, we can use it to help someone else. Families can also find creative ways to connect generosity with celebrations. Sharon suggests hosting a “reverse birthday party,” where guests bring items for a ministry or charity the child helps select. Another simple practice is keeping blank cards nearby so children can draw pictures or write encouraging notes for someone who may be lonely, sick, or going through a difficult season. None of these activities requires a child to understand complex financial concepts. They simply allow children to see generosity in action. Give Children Hands-On Opportunities to Serve As children grow, parents can begin inviting them into more direct experiences of giving. One powerful approach is volunteering together at a local ministry, especially an organization serving other children or families. Serving side by side allows generosity to become something children experience personally rather than merely hear about. Families might also consider sponsoring a child through a trusted ministry. Sharon shared how her own daughter began sponsoring a child at age five and continued that relationship as they both grew older. Experiences like these can help children recognize that generosity is relational. It is not simply about transferring money from one place to another. It is about seeing people, caring about their needs, and responding with compassion. Connect Generosity to a Teenager's Passions As children enter their teenage years, their interests and passions become clearer. That creates an opportunity to help them connect generosity with the things they already care about. A teenager who loves the outdoors, for example, might become interested in supporting a Christian camp ministry. A young person passionate about sports might enjoy serving through an organization that uses athletics to mentor children. Families can also make service part of their normal rhythms. Spring break or other holidays, for instance, can include opportunities to serve together. Sharon shared that her children participated in spring break mission trips while growing up. Those experiences became so meaningful that they continued serving during college because generosity had simply become part of what their family did. That is one of the most powerful lessons parents can pass along: Generosity is not an occasional project. It can become part of the way we live. Let Generosity Involve Sacrifice Biblical generosity often involves more than giving from what is left over. Sometimes it requires choosing to give something up so that someone else can benefit. Teenagers are old enough to begin experiencing that kind of sacrifice intentionally. One creative idea is a “pantry challenge,” where a family spends a period of time eating primarily what is already in the house while limiting grocery purchases. The money saved could then be given toward a ministry or someone in need. Practices like this help young people understand that generosity involves choices. We may choose to spend less so we can give more. We may give up some of our time to serve. We may share our skills, possessions, or opportunities with someone else. Sacrifice helps generosity move from an abstract idea to a lived experience. Encourage Generosity Into Adulthood Parents can continue encouraging generosity even after their children become adults, but their role begins to change. Rather than directing their children's giving, parents can create opportunities for them to make their own decisions. One option Sharon suggests is helping an adult child establish a donor-advised fund. Parents might provide an initial amount and even offer to match what their child contributes toward charitable giving. The purpose is not simply to create another financial account. It is to encourage intentionality. What causes do they care about? Where do they see God at work? How might the resources entrusted to them become part of that work? Questions like these help adult children develop their own convictions about generosity and stewardship. Expand Your Family's Definition of Giving Perhaps one of the most important lessons families can learn is that generosity is about far more than money. We can give our time. We can offer our skills. We can share our relationships, possessions, influence, and opportunities. This broader understanding allows generosity to become what Sharon describes as “whole-life, purpose-filled generosity.” And that means every member of the family has something to give. A young child can draw an encouraging picture. A teenager can spend a Saturday serving. An adult can use financial resources, professional skills, or relationships to help others. Generosity begins by asking a simple question: What has God entrusted to me that I can use for the good of someone else? Generosity Is Often Caught More Than Taught Parents can certainly talk with their children about giving, but some of the most powerful lessons will come from what children see practiced consistently at home. When they watch their parents give joyfully, serve willingly, and hold their resources with open hands, they begin to understand that generosity is not merely something Christians do. It is part of who we are becoming as faithful stewards. And when families practice generosity together—from childhood through adulthood—they plant seeds that may continue bearing fruit long after the original gift has been given. A generous family legacy is ultimately about more than what we leave to the next generation. It is about helping prepare the next generation to faithfully steward whatever God places in their hands. On Today's Program, Rob Answers Listener Questions: I have an annuity and want to borrow $200,000 to buy an investment property. I've been told I could qualify for the loan based on my assets, then withdraw from the annuity to pay it off without owing taxes because the withdrawal wouldn't be earned income. Is that correct, or would the annuity withdrawal still be taxable? I set up a trust for my wife while she was living with Alzheimer's, and she passed away a couple of years ago. How often should a trust be reviewed, and should I update or redo it now? I have about $250,000 in home equity and a 3.85% mortgage, so I don't want to do a cash-out refinance. Are home equity sharing agreements a legitimate option, and what should I know before considering one? I'm 62, single, and have property and investments. I want to get my estate in order. What's the difference between a will and a trust, do I need a power of attorney, and what's the best way to get these documents set up? Resources Mentioned: Faithful Steward: FaithFi's Quarterly Magazine (Become a FaithFi Partner) Women Doing Well Movement Mortgage Trust & Will Home Equity and Reverse Mortgages: The Cinderella of the Baby Boomer Retirement by Harlan Accola FaithFi Field Guide: How Much Money is Enough? Our Ultimate Treasure: A 21-Day Journey to Faithful Stewardship by Rob West Wisdom Over Wealth: 12 Lessons from Ecclesiastes on Money Look At The Sparrows: A 21-Day Devotional on Financial Fear and Anxiety Rich Toward God: A Study on the Parable of the Rich Fool Find a Certified Kingdom Advisor® (CKA) FaithFi App Remember, you can call in to ask your questions every weekday at (800) 525-7000. Faith & Finance is also available on Moody Radio Network and American Family Radio. You can also visit FaithFi.com to connect with our online community and partner with us as we help more people live as faithful stewards of God's resources. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Published in the Alzheimer's & Dementia Journal, the study said that even though India's ageing population faces a ‘dementia burden', data on what its risk factors actually are is still quite limited.
What emotions can you recognize in your body while they are happening?For many of us, the list is limited to happy, sad, and angry. But trying to understand your emotional experience with only three words is like trying to draw a sunset with three crayons. You might capture the general idea, but you will miss important shades, details, and information.In Part 2 of the Name It to Navigate It series, Amy helps you expand your emotional vocabulary so you can identify what you are actually feeling—not just the broad category it falls into.You will learn how to use the Wheel of Emotions as a practical tool, why feelings such as envy and jealousy require different responses, and how accurately naming an emotion can help you understand what you need.Because when you can name what is happening more precisely, you are better able to pause, examine the story you are telling yourself, and choose a response that supports your brain health, well-being, and values.This episode builds on Part 1, where Amy introduced affect labeling—the practice of putting feelings into words—and explained how naming an emotion may help quiet the brain's alarm system and bring your thinking brain back online.WHAT TO LISTEN FOR:00:00 — Why three emotion words are not enough02:15 — The difference between an emotion and a feeling04:45 — Why emotional awareness gives you useful information06:30 — How emotional vocabulary works like a map08:20 — How to use the Wheel of Emotions11:40 — What emotions may be trying to tell you13:50 — Envy versus jealousy15:40 — Stress versus overwhelm and guilt versus shame18:10 — Fear, powerlessness, and Alzheimer's risk21:15 — A journaling practice for naming what you feelThe more accurately you can name what you feel, the more clearly you can understand the need beneath it. That clarity creates a pause between the feeling and the action, giving you the opportunity to respond in a way that aligns with your wants, needs, values, and long-term brain-health goals.Listen to Part 2 now, subscribe to Happy & Healthy with Amy, and come back for Part 3, where Amy explores why an urge can feel like a command—and how to deal with them when they undermine your long-term goals.RECOMMENDED EPISODES:The One About TLCNotice and Name It: The Brain Science of Putting Feelings Into WordsAfter an Alzheimer's Diagnosis: A Family ChecklistAlzheimer's Drugs: Why Amyloid Removal May Not Be EnoughRESOURCES:Download the FREE Excerpt of Thoughts Are Habits TooPurchase Thoughts Are Habits TooBook a FREE Discovery Call with AmyDownload After Mom's Alzheimer's Diagnosis: The First 8 Things to Know and learn how to support her with more calm, clarity, and confidence.Download the RESTORED Protocol: Eight Essential Protective Factors to Build an Alzheimer's-Resistant BrainSchedule your Breakthrough Roadmap session with AmyFollow Amy on Instagram @amylangcoaching and on Facebook @amylangcoachingSubscribe to Amy's YouTube channel @happyandhealthywithamy
Brain Talk | Being Patient for Alzheimer's & dementia patients & caregivers
The experience of dementia, for people living with memory loss and for the family members and friends who care for them, is often told through the language of loss. But there is a growing effort to change that, creating work that centers connection, humanity, and what remains. One of those projects is “Memory Generation,” an interview-based theater production set in a memory cafe, where people affected by dementia gather in a space built around creativity and community.Memory Generation was created by Sara Zatz and Sherrine Azab and premiered this year at La MaMa in New York City. Zatz is the artistic director of engagement at Pink Fang,, where she develops community-based work rooted in first-hand interviews. Azab is a Detroit-based theater director and co-director of the ensemble A Host of People. Both drew on their own experiences as family caregivers for loved ones living with dementia, as well as interviews with people across the country and the lived experiences of the show's performers.In this Live Talk with Being Patient's Mark Niu, Zatz and Azab discussed how they built the production, why they set it inside a memory cafe, and how they worked to portray caregiving without reducing it to its hardest moments. They also reflected on questions of consent and whose stories get told, the strain that limited resources place on caregivers, and how the arts and community might help build what they describe as a more dementia-friendly society.---If you loved this Live Talk, visit our website to find more of our Alzheimer's coverage and subscribe to our newsletter: https://www.beingpatient.com/Follow Being Patient: Twitter: https://twitter.com/Being_Patient_Instagram: https://www.instagram.com/beingpatientvoices/Facebook: https://www.facebook.com/beingpatientalzheimersLinkedIn: https://www.linkedin.com/company/being-patientBeing Patient is an editorially independent journalism outlet for news and reporting about brain health, cognitive science, and neurodegenerative diseases. In our Live Talk series on Facebook, former Wall Street Journal Editor and founder of Being Patient, Deborah Kan, interviews brain health experts and people living with dementia. Check out our latest Live Talks: https://beingpatient.com/live-talks/
A neuroscientist who also writes novels – including one that became an award-winning movie – Lisa Genova lets us experience the stories lived by people with brain diseases ranging from Alzheimer's to bipolar disorder. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Ask most people what a brain chip does and they will tell you it reads your mind. Dr. Michael Lawton implants these devices, and he says that is not what comes off them. He is President and CEO of Barrow Neurological Institute in Phoenix, the hospital where Neuralink's first human implant was performed, and he has completed more than 10,000 brain operations and clipped around 5,500 aneurysms. Louisa sat down with him inside Barrow to find out what the electrodes actually pick up, how far the technology has come, and where it stops. He walks through the surgery itself. The device goes into the hand knob, one small lobule of the motor cortex, where 64 electrodes have already become 108. The threads carrying them are about a tenth the thickness of a hair, so a robot inserts them while avoiding every arteriole on the surface. You'll hear what Nolan Arbaugh, Neuralink's first patient, can now do with a cursor at world record speed, and why Lawton can't keep up with him in a head to head. *Reduce your risk of Alzheimer's with my science-backed protocol for women 30+:* https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ *TOPICS DISCUSSED* 00:00 Intro: The Brain Surgeon at Neuralink's First Hospital 00:39 The Guy Who Does the Cases Nobody Else Wants 02:17 A Day in the Life: 5:30am Starts and Three Surgeries 03:20 "Game Tape": Reviewing Every Operation Like an Athlete 04:24 The Surgeon Athlete and Why Surgery Is a Physical Skill 05:32 Fifty Years From Now: What Happens to Neurosurgery 06:11 The ROSA Robot and Mapping a Seizure Focus 08:16 Deep Brain Stimulation and Hitting an Exact Target 08:52 Will We All Be Operated On by Robots? 10:02 The Brain AVM: The One Case a Robot Can't Take 11:18 Why Bleeding Breaks a Robot: The Waymo Problem 13:15 What a Brain-Computer Interface Actually Does 14:49 The Hand Knob: 108 Electrodes in One Small Spot 15:50 Cursor Control at World Record Speed 16:31 Inside the Implant: Threads a Tenth the Width of a Hair 17:27 "No, the Chip Cannot Read Your Thoughts" 17:58 What the Device Really Reads: A Train of Spikes 19:18 From Movement to Sensation: What Comes Next 19:48 Why Restoring Sight Is So Much Harder 20:58 The 1943 Paper That Predicted All of This 22:37 Elon, Telepathy, and What's Actually Possible 23:00 Boosting Creativity and Intelligence in 50 Years 25:10 "When I Retire, We'll Be Treating Depression and Addiction" 26:04 Alzheimer's: Light Therapy and the Blood-Brain Barrier 27:11 Treating the Disease vs Preventing It 28:25 10,000 Operations: How He Feels About Robots Taking Over 29:54 Neuroplasticity: How Nolan's Brain Learned the Device 31:34 What Actually Changes at the Neuron Level 32:04 Patient Two and the Robotic Arm 32:42 5,500 Aneurysms: The Cases That Stay With Him 33:16 Cardiac Standstill: Cooling a Brain to 15 Degrees 35:46 What Separates a Great Surgeon From an Average One 36:17 Traits of Greatness: The Formula Nobody Has Cracked 37:21 The Phone Call in the Middle of a 16-Hour Surgery 39:35 "I Must Have Been Born for This" 41:26 Can You Tell How Old a Brain Is Just by Looking? 43:12 Why Alzheimer's Is Invisible in a Living Brain 44:14 What a Neurosurgeon Does to Protect His Own Brain 44:40 "Alcohol Will Be Viewed Like Cigarettes in the 60s" 45:13 Peptides, Injectables, and Zero Supplements 46:52 The Last Generation to Operate With Open Hands 48:10 How Louisa Found Him on Twitter in 2021 48:53 The Six Mysteries of the Mind 49:14 Which One Gets Solved First, and Which May Never 50:03 Is Consciousness in the Tissue? 51:39 Memory: The Circuitry We Still Can't Explain 53:18 Why Consciousness Is Harder Than Memory 55:12 Louisa's Father's Stroke 56:02 Advice for Anyone Watching a Parent Decline 56:21 His Sister's Brain Tumor and How He Carries It 57:38 A World Where Stroke Is an Outpatient Repair 58:40 Forty Years On, Finally at the Dawn _______ *Thank you to our sponsors* Timeline (Mitopure): https://timeline.com/neuro Mitopure now starts at $79 Ogee: https://ogee.com Use code NEURO for a discount on the Crystal Contour Collection Kion (Kion Aminos): https://getkion.com/neuro for a 20% discount Function Health: https://functionhealth.com/LouisaNicola Use code NEURO25 for a $25 credit _______ I'm Louisa Nicola - clinical neurophysiologist - Alzheimer's prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer's risk - and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices
Gary reads the second part of his latest essay - How to Manifest Your Authentic Self and the latest on Health and Healing. HEALTH NEWS Ancient grain sorghum shows potential against Alzheimer's in early cell research Daily multivitamin improves functional health in older adults, study finds Kids who own cellphones have poorer reading comprehension scores than those who don't, researchers find Time-restricted eating may help retain cognitive function in older adults Exercise Rewires Heart's Nerve Network in Left-Right Pattern Ancient grain sorghum shows potential against Alzheimer's in early cell researchEdith Cowan University & Alzheimers Research Australia, July 27 2026 (Natural News) Sorghum polyphenols reduced toxic amyloid-beta buildup in brain cells by up to 76 percent in a laboratory study. Scientists extracted polyphenols from three varieties of sorghum — black, red-brown and red — and exposed cultured human brain cells to amyloid-beta, the sticky protein long implicated in Alzheimer's plaque formation. Black sorghum showed the strongest protective effect on cultured human brain cells. Treated cells had over 70 percent better survival and 80 percent more active mitochondria. The findings still require animal studies before any health claims. Sorghum is gluten-free, fiber-rich, and loaded with the same class of plant compounds found in berries, olive oil, tea and dark chocolate — nutrients researchers have long connected to healthier brain aging. Daily multivitamin improves functional health in older adults, study finds Medical College of Georgia at Augusta University, July 27 2026 (News-Medical) The ability to perform everyday activities free of debilitating symptoms profoundly affects quality of life as we age. In a new study, older adults who took a daily multivitamin had significantly better measures of functional health after 3 years compared with those who took a placebo. According to researchers, the findings suggest a daily multivitamin can help older people maintain day-to-day functioning by helping to preserve cognitive abilities, and it may also benefit blood circulation and physical stamina. The researchers analyzed data from over 16,000 people aged 60 years and older. Participants were randomly assigned to take a daily multivitamin, a cocoa extract supplement, both or neither, with placebos used for the control group and for those taking only one supplement. After 3 years, participants taking a multivitamin had significantly better functional health than those taking a placebo. Kids who own cellphones have poorer reading comprehension scores than those who don't, researchers find University of California at Los Angeles, July 27 2026 (Eurekalert) The widespread concern about the effect of cellphones on reading comprehension in elementary school children has led to surprisingly little experimental research. New research by UCLA psychologists found a statistically significant relationship between owning a cellphone and lower reading scores — children who owned cellphones had poorer reading comprehension than those who did not. This negative relationship between phone ownership and reading scores held for students who spoke English at home and those who did not. In fact, simply owning a phone correlated with worse reading comprehension, whether or not the phone was brought to school. Time-restricted eating may help retain cognitive function in older adults Rutgers University, July 27 2026 (Medical Xpress) Results from a small clinical trial suggest it may be possible to reduce the risk of dementia by eating during fewer hours of the day. The pilot study, which involved a weight-loss program for older women with overweight or obesity, showed modest cognitive improvements among those who limited their daily eating window instead of just reducing their calorie intake. The trial enrolled 47 women ages 50–79 who were overweight or obese. All participants were counseled to reduce their calorie intake by 500 calories per day. Twenty-six participants were asked to restrict their eating to a window of less than nine hours per day, while the rest maintained a typical eating window of about 12 hours per day. In the time-restricted eating group, participants generally ate only between 10 a.m. and 6 p.m., with an average daily eating window of 8.2 hours, compared with an average of 12.3 hours per day among those asked to maintain the standard eating window. After six months, participants had lost about 15 pounds (6.8 kilograms), on average, about the same in both groups. Compared with participants who maintained a 12-hour eating window, those who consumed food for only 8–9 hours per day showed significant improvements in spatial planning and problem-solving at the end of the weight-loss program. They also showed a trend toward fewer errors on memory and learning tests, but there was no significant difference in performance on multitasking or reaction-time tests. Exercise Rewires Heart's Nerve Network in Left-Right PatternUniversity of Bristol (UK), July 21, 2026 (Natural News) Regular aerobic exercise reshapes the nerves that regulate the heart, according to a study from the University of Bristol. The study found that after 10 weeks of training, rats showed asymmetric changes in the stellate ganglia nerve clusters -- paired structures in the lower neck and upper chest that send “go faster” signals to the heart. The discovery reveals a previously hidden left-right pattern in the body's “autopilot” system for the heart. This finding could eventually help doctors tailor treatments for arrhythmias, angina, and stress-induced “broken-heart” syndrome, according to the researchers. Using advanced three-dimensional imaging techniques called stereology, the team examined nerve cluster changes after the exercise regimen. Trained rats had about four times as many neurons in the right cardiovascular nerve cluster compared with the left, relative to untrained animals. At the same time, neurons on the left side nearly doubled in size, while those on the right became slightly smaller, the researchers reported. Dr. Coppi described the nerve clusters as acting like “the heart's dimmer switch,” noting that exercise remodels that switch in a side-specific way. The stellate ganglia are part of the sympathetic chain, which regulates heart rate and contraction force, as described in functional anatomy texts. The asymmetric changes suggest that aerobic training induces a previously unrecognized form of
"You have to figure out how to make self-care a priority because you know the body does not sit still... Your mindset will allow you to move forward, or it will take you backwards." —Dr. Mitra Ray Stanford-trained biologist Dr. Mitra Ray spent three decades building a career in women's longevity, but the habits she taught everyone else became something she never expected: the infrastructure that kept her upright after her husband, Doug, died suddenly in a paragliding accident in October 2023. In this conversation with host Justine Reichman, Dr. Ray traces her path from NIH- and Alzheimer's-funded cancer research to walking away from the lab, building a word-of-mouth wellness brand that sold 2 million copies with zero advertising, and eventually testing her own biological age during the hardest year of her life — and watching it go backward. This episode is for anyone navigating midlife, grief, perimenopause, or the quiet realization that the wellness habits they've dismissed as trendy might be the thing holding them together. Dr. Ray and Justine talk candidly about cold plunging, sobriety, plant-based nutrition, sleep science, and the gut-microbiome research behind cravings — grounding every claim in the biology, not the buzzwords. Key takeaways: Dr. Ray's biological age measurably reversed during the year she grieved her husband, evidence that consistent habits can outperform circumstance. Comparing your current body to a memory of your 25-year-old self is biologically counterproductive — memories change every time you access them, and the comparison itself triggers cortisol and inflammation. Cold plunging activates the anterior mid-cingulate cortex, the brain region tied to willpower and will to live, which Dr. Ray leaned on deliberately after losing Doug. Food cravings are largely dictated by gut bacteria, not willpower — feeding plant-based bacteria gradually shifts what your body craves. "Superagers" in their 80s are still generating new neurons, making neurogenesis — not a return to a younger self — the more useful benchmark for healthy aging. Grief lives in the body: cortisol, thyroid, and hormone levels shift during loss, and naming that process without judgment is part of recovering from it. Listen to the full conversation and subscribe to Essential Ingredients for more real conversations at the intersection of food, purpose, and building a better future: https://tinyurl.com/Essential-Ingredients-Podcast Meet Dr. Ray: Living a long, healthy life is not as complicated as the wellness industry would have you believe. Dr. Mitra Ray has spent more than 30 years helping people understand this, and more importantly, live it. Her path into health was shaped by both rigorous science and lived experience. She completed her undergraduate degree at Cornell University and earned her PhD from Stanford Medical School, where her research was funded by multiple NIH grants and recognized with the Young Investigator Award from the Federation of American Societies in Experimental Biology. Her work has been published in Science, Proceedings of the National Academy of Sciences, and the Journal of Cell Biology: journals that do not publish ideas lightly. But credentials alone do not explain why audiences across four continents keep coming back to hear her speak, or why her books and lectures on health, beauty, brain function, and longevity have resonated as widely as they have. The reason is simpler: she translates what the science actually says into something you can do and sustain. Her focus has always been whole plant foods, an active body, and a clear mind. These three things, she has come to understand, are not a wellness trend. They are the foundation. Everything downstream of that foundation- how you look, how you feel, how you age- follows. The Elder's Evolution, her Substack publication, is where she writes about what it means to age well, with full attention paid to both the biology and the deeper questions that biology alone cannot answer. Website LinkedIn Instagram Substack Connect with NextGen Purpose: Website Facebook Instagram LinkedIn YouTube Podcast Chapters: 01:31 Meet Dr. Mitra Ray: From Stanford Lab to Wellness Pioneer 05:41 Leaving Science: How Her Family and Peers Reacted 09:03 Why Doctors Still Ignore Whole-Food Nutrition 16:52 Stop Comparing Yourself to a Body That No Longer Exists 19:45 Building a 2-Million-Copy Word-of-Mouth Wellness Brand 23:03 After Doug's Death: The Habits That Became Her Infrastructure 32:36 Cold Plunging, the AMC, and Rebuilding Willpower After Loss 51:02 The Real Benchmark for Aging Isn't Your 25-Year-Old Self 54:34 Cravings Aren't Willpower — It's Your Gut Microbiome
Join us for a live Q&A with Dr. Ben Bikman here.For the 100th episode of The Metabolic Link, Ben Bikman, PhD, professor of cell biology and physiology at Brigham Young University and author of Why We Get Sick, returns for a milestone conversation with co-hosts Dominic D'Agostino, PhD, and Victoria Field. Together, they examine what clinicians are measuring, what conventional approaches may be missing, and how the science of metabolic health continues to evolve.Bikman argues that the clinical picture of metabolic health remains glucose-centric and lipid-heavy while the earliest signal, elevated insulin, goes unmeasured. He explains why women stay insulin sensitive at far higher body fat than men and what menopause takes away, why visceral fat is misunderstood, and how a fatty liver can be miscounted as lean mass on a DEXA scan. That last point is why he now says he was wrong about GLP-1 drugs, and why he thinks they should be prescribed as something other than weight loss medication.Questions Answered in This Episode:• Why does standard bloodwork detect metabolic dysfunction so late?• Why are women more insulin sensitive than men at the same or higher body fat?• What actually changes metabolically during menopause?• Is visceral fat inherently dangerous, or is something else going on?• Why did Dr. Bikman change his position on GLP-1 medications?• Should GLP-1 drugs be prescribed as weight loss drugs at all?This milestone episode offers a rigorous, physiology-first look at where metabolic science stands today, and what researchers and clinicians may need to examine next.Thank you for listening, watching, sharing these conversations, and helping us reach 100 episodes. We're incredibly grateful to have you as part of this community.Special thanks to the sponsors of this episode:Genova Connect: Get 15% off any Genova Connect test kit with code METABOLICLINK here.Cowboy Colostrum: Get up to 25% off with code METABOLIC here.iRestore: Get a special discount on the iRestore Illumina face mask with code LINK here.More LinksDr. Ben Bikman's website: benbikman.comInsulin IQ: insuliniq.comYouTube: youtube.com/@benbikmanInstagram: @benbikmanphdFeatured study: White Matter Lipids as a Ketogenic Fuel Supply in Aging Female Brain: Implications for Alzheimer's DiseaseIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: InstagramFacebookYouTubeLinkedInPlease keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.
SPONSORS: NOCD -If you're struggling with OCD or unrelenting intrusive thoughts, NOCD can help. Book a free 15 minute call to get started ZocDoc -Taking care of your health just got easier – start here with Zocdoc: https://zocdoc.com/HONEYDEW #sponsored Che Durena joins me this week on The HoneyDew to Highlight the Lowlights of a childhood that sounds too unbelievable to be true. Che talks about growing up on property that was once owned by notorious Canadian serial killer Willie Pickton! He also shares what it was like growing up with one testicle, spending six months living in a shelter, watching his father's battle with Alzheimer's, and saying goodbye to the family dog that was there through it all. Check out Che's special, How to Make Your Balls Bigger, and his podcast Two Goons. SUBSCRIBE for new episodes of The HoneyDew every week.
What if the fatigue, brain fog, joint pain, or mysterious symptoms you've been chasing for years weren't caused by stress, aging, or burnout—but by a tick bite you never even noticed? Lyme disease is one of the most misunderstood illnesses in medicine. But Lyme is rarely just one infection—it's often part of a much bigger picture involving co-infections, immune dysfunction, inflammation, gut health, and environmental triggers. In today's episode, I walk through a functional medicine approach to Lyme disease and tick-borne illness, including: Why Lyme disease is so often missed—and the hidden role of co-infections like Babesia, Bartonella, Ehrlichia, and Anaplasma The limitations of conventional testing and treatment, and how functional medicine looks beyond the infection to understand why some people recover while others remain chronically ill The role of herbs, antibiotics, gut repair, detoxification, immune support, and mitochondrial health in a comprehensive recovery plan What the latest evidence says about emerging therapies like ozone, hyperbaric oxygen therapy, and hyperthermia—as well as practical strategies to prevent tick-borne illness in the first place Lyme disease isn't always just an infection—it's often a whole-body disruption. By addressing the underlying drivers of inflammation, immune dysfunction, gut health, and cellular resilience alongside the infection itself, you give your body the best chance to heal and recover. Resources Mentioned: Track your metabolic health with Function Health: https://functionhealth.com/mark (Use code MARK2026 for $50 off your membership.) Have a question you'd love answered on Office Hours? Submit it here (0:00) Introduction to Lyme disease, overview, and Dr. Hyman's experience (4:13) Functional medicine's approach and comprehensive treatment strategies (10:51) Innovative therapies for Lyme disease (14:08) Managing die-off reactions and restoring gut health (17:18) Supporting the immune and nervous systems; prevention strategies (19:29) Future research, persistent symptoms, and conclusion (21:15) Alzheimer's disease, neuroinflammation, and call to action
Nvidia is in talks with OpenAI to finance a new data center project in Ohio, according to reports. As markets kick off the busiest week of earnings season, investor Steve Eisman shares his perspective on the AI trade, big tech's big capital expenditures, the moats around tech and AI companies, and how he's hedging his own portfolio. CNBC's Dan Murphy reports on the current pause in fighting between the U.S. and Iran, and RBC Capital Markets' Helima Croft discusses the conflict's impact on the energy markets. Plus, PharmatrophiX co-founder and Stanford Professor Dr. Frank Longo explains Compound 31, a new FDA-approved drug to treat Alzheimer's. He shares his personal journey toward medical innovation in the field, and shares the differentiators between Compound 31 and the Alzheimer's treatments that have come before it. Dan Murphy - 07:50 Helima Croft - 12:43 Steve Eisman - 22:36 Dr. Frank Longo - 34:43 In this episode: Joe Kernen, @JoeSquawk Becky Quick, @BeckyQuick Dan Murphy, @dan_murphy Katie Kramer, @Kramer_Katie Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Testosterone, not GLP-1s, is what finally let Chalene Johnson lose body fat and build real muscle after 40, and she's laying out exactly how in this episode. Chalene explains why her total testosterone always looked normal on paper while she still felt exhausted and stuck in the gym, until a clinician finally tested her free testosterone and SHBG (sex hormone binding globulin) and found the real problem. In her words, total testosterone is the money in the bank, free testosterone is the cash in your pocket, and SHBG is the bank teller deciding how much you actually get to spend. She also gets into why she skipped the growth peptides everyone's talking about (tesamorelin, ipamorelin, CJC-1295) and switched from monthly testosterone injections to a daily cream instead. She talks candidly about the mold exposure that wrecked her hormones, caregiving through her father-in-law's Alzheimer's, and why she stopped weighing herself and started tracking body fat with an InBody scale instead. Topics discussed: testosterone for women, free testosterone, total testosterone, SHBG, hormone replacement therapy, perimenopause, GLP-1, tesamorelin, ipamorelin, CJC-1295, HGH, IGF-1, progressive overload, body composition, InBody scale, DEXA scan, mold toxicity, testosterone cream Midi Health testosterone for women: https://chalene.com/test Midi Health hormone and menopause care: https://chalene.com/midi Go Beyond The Podcast Join Chalene on her private podcast