Progressive, neurodegenerative disease characterized by memory loss
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80% of all autoimmune diseases occur in women, and no one can explain why. Cancer cells are always present in your body, but it's only when your T cells go into energy deficit that cancer starts overtaking the system. And here's what almost no one is talking about: the mitochondria in your immune cells are the reason MS, chronic fatigue, neurodegeneration, and even cancer progression happen when they happen. In this episode, I sit down with Dr. Anurag Singh, MD, PhD immunologist who spent 20 years studying mitochondria and screened 4000 compounds from pomegranates to discover one molecule that changes cellular aging. We break down immunometabolism, the emerging field linking immune health and metabolism, why your T regulatory cells are the CEOs of your immune system, how mitochondrial dysfunction in immune cells triggers autoimmune conditions, and why rejuvenating mitochondria can get your immune system in check to defeat cancer. We also cover NAD+ (and why NMN and NR supplements don't work the way people think), the creatine sweet spot for muscle quality (500mg-1g, not the 5g everyone's taking), why Parkinson's is linked to paraquat, a mitochondrial toxin used in fertilizers and dry cleaning and how AI is fast-tracking the discovery of next-generation molecules for neurodegeneration. This conversation completely shifted how I think about immune health, brain protection, and what's actually driving the diseases we fear most. Reduce your risk of Alzheimer's with my science-backed protocol for women 30+: https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ TOPICS DISCUSSED 00:00 Intro: Why 80% of Autoimmune Diseases Occur in Women 01:24 Why Dr. Anurag Became an Immunologist 03:19 Immunometabolism: The Link Between Immune Health and Metabolism 04:20 T Cells, B Cells, and the Thymus Gland 05:51 MS and Autoimmune Disease: The T Regulatory Cell Problem 11:32 Mitochondrial Dysfunction and Immune Exhaustion 18:45 Cancer Cells and T Cell Energy Deficit 24:10 Urolithin A: Screening 4000 Pomegranate Compounds 31:20 Mitophagy and Autophagy: Cellular Housekeeping 38:50 NAD+ vs NMN and NR Supplements: What Actually Works 43:15 Creatine Dosing: The 500mg-1g Sweet Spot for Muscle Quality 48:30 Gut-Brain Connection and Neurodegeneration 50:54 Parkinson's Disease and Paraquat: The Mitochondrial Toxin 53:25 AI in Drug Discovery and Next-Generation Molecules 55:38 Skincare and Mitochondrial Health: Collagen Synthesis _______ Thank you to our sponsors KetoneIQ: https://ketone.com/NEURO for 30% OFF Caraway: Carawayhome.com/neuro10 Jones Road Beauty: https://www.jonesroadbeauty.com - Use code NEURO _______ I'm Louisa Nicola - clinical neurophysiologist - Alzheimer's prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer's risk - and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices
This episode is sponsored by LMNT and Cozy Earth. LMNT - Get a free 8-count Sample Pack of LMNT's most popular drink mix flavors with any purchase at https://drinklmnt.com/FLIPPING50. Cozy Earth - Discover how care in every detail transforms simple routines into moments of true comfort and ease. Head to cozyearth.com and use my code Flipping50 for up to 20% off. Other Episodes You Might Like: Previous Episode - 6 Menopause Fitness Questions From the Community Next Episode - Making Fasting a Tool and Sparing Muscle Loss During Fat Loss More Like This: Your Hormones Are Quietly Changing Your Gut and It's Affecting Your Longevity Heal Your Gut, Save Your Brain Resources: Don't know where to start? Book your Discovery Call with Debra. Leave this session with insight into exactly what to do right now to make small changes, smart decisions about your exercise time and energy. Use Flipping 50 Scorecard & Guide to measure what matters with an easy at-home self-assessment test you can do in minutes. Gut health and migraines may be more connected than you've ever been told — and if you've been waiting for your migraines to “just go away” after menopause, this episode might change everything. Migraines are now being viewed as a symptom of deeper dysfunction in the brain, gut, mitochondria, and vascular system — not just a hormonal inconvenience. If you're tired of powering through, relying on quick fixes, or wondering why nothing seems to work long-term, this episode gives you a smarter path forward. We might have been overlooking the missing link between gut health and migraines. My Guest: Dr. Amelia Scott Barrett is a Stanford-trained neurologist and founder of Migraine Relief Code, where she pioneers a precision medicine approach to chronic headaches and migraine. She created the first genetic testing panel designed specifically for people with migraine, helping patients identify their unique Genetic Headache Type and follow customized recovery protocols that combine medical care, nutrition, supplements, and lifestyle strategies. A TEDx speaker and author of the upcoming book ALIGN: Live the Way You're Wired to Relieve Headaches + Migraine for Good, her work has been featured in Business Insider and Women's World. After launching her private neurology practice in Denver in 2003, she founded Migraine Relief Code in 2019 to bring personalized, science-driven solutions to people worldwide. Dr. Barrett is passionate about addressing migraine as a women's health crisis, empowering women to relieve pain, protect their earning power, and reclaim their lives. Questions We Answer in This Episode: [00:12:17] What are some of the genetic problems that can cause issues with gut health and migraines? [00:20:02] What is your #1 recommendation that women can start now for improving gut health and reducing migraines? [00:22:06] What medications work for migraine? [00:29:40] Is there a connection between chronic migraine with dementia or Alzheimer's? [00:31:40] What can women in midlife do to help improve the gut and reduce migraine severity or frequency? What is the importance of fiber with migraine? [00:37:44] How is inflammation related to migraine?
Nutritional Support for Brain Health: Lifestyle, Curcumin, Magnesium, and Key Nootropics: Nutrition educator/formulator Neil Levin from Protocol for Life Balance details nutritional support for brain health amid skepticism about “brain-boosting” supplements, citing a preprint randomized controlled trial using a multifaceted lifestyle plan (diet, exercise, sleep) plus targeted supplementation that reportedly improved and even reversed symptoms in people with mild cognitive impairment. They contrast lifestyle strategies with costly, side-effect-prone injectable “plaque-buster” Alzheimer's drugs and notes debate about whether amyloid is a root cause or byproduct. The conversation highlights inflammation and oxidation as major aging-related brain threats and reviews supplements including a brain-targeted curcumin (discussing bioavailability, delivery methods, blood–brain barrier crossing, and claims of lowering beta-amyloid protein), magnesium L-threonate for CNS delivery, phosphatidylserine and acetylcholine support (including huperzine), ginkgo and gotu kola, glutamine/GABA pathways, creatine, omega-3s (DHA/EPA and algae sources), B vitamins, acetyl-L-carnitine, alpha-lipoic acid, and cocoa flavanols, plus concerns about supplement industry enforcement.
The new semi-autobiographical play “The Reservoir” spins a comedic narrative around cognitive reserve, the idea that doing brain-stimulating activities can prevent or delay the onset of dementia symptoms. It's currently running at the Atlantic Theater Company and co-produced by The Ensemble Studio Theater in New York.* Host Ira Flatow talks with playwright Jake Brasch about his inspiration for the play and how to mesh science into the theater. Then, neurologist Marilyn Albert discusses some of the latest science of mental stimulation and dementia. After following a diverse group of older adults for 20 years, her research found that a modest amount of specialized cognitive training reduced dementia risk by 25%. You can try a very similar brain training exercise at home. *“The Reservoir” received funding from the Sloan Foundation, which also helps support Science Friday. Guests: Jake Brasch is a writer, performer, composer, clown, and writer of the new play “The Reservoir.” Dr. Marilyn Albert is a professor of neurology and director of the Alzheimer's Disease Research Center at Johns Hopkins Medicine.Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.
In this episode, David Watumull breaks down the science behind astaxanthin — a powerful carotenoid antioxidant backed by over 4,000 peer-reviewed papers and 100+ human clinical trials — and explains why it may be one of the most underappreciated longevity compounds available today. The conversation explores how astaxanthin anchors across cellular membranes to protect mitochondria from oxidative stress, reduce chronic inflammation ("inflammaging"), support cardiovascular health by lowering oxidized LDL and CRP, and cross the blood-brain barrier to enhance cognitive function and neuroprotection. They also discuss its role in energy production, endurance performance, healthy aging, and a landmark NIH lifespan study showing a 12% extension in mammals. Ultimately, the episode reframes longevity not as chasing stimulants or shortcuts, but as protecting cellular integrity so the body can function the way it was designed to — for longer and at a higher level. ----- 00:00 – The Longevity Molecule You've Never Heard Of 02:45 – What Is Astaxanthin? 07:30 – How It Protects Your Cell Membranes 13:40 – Free Radicals & Oxidative Stress Explained 25:50 – Brain Health, Neuroplasticity & Mitochondria 29:40 – Cardiovascular Disease & Oxidized LDL 34:05 – Alzheimer's, MCI & Neuroprotection 43:00 – Energy Production & Mitochondrial Function 58:40 – Inflammaging & Longevity Pathways 1:03:40 – NIH Study: 12% Lifespan Extension 1:09:00 – Athletic Performance & Endurance 1:15:00 – Dosing, Absorption & Bioavailability 1:26:00 – Can Antioxidants Become Harmful? 1:30:00 – Why Isn't This Mainstream? 1:37:30 – Living Ever Forward ----- Episode resources: Save 20% with checkout code EVERFORWARD at https://www.AX3.Life.com Watch and subscribe on YouTube Learn more at https://ax3.life/pages/science
Matt Walker investigates the "coffee paradox," revealing how your morning ritual acts as both a health ally and a silent sleep disruptor. While coffee provides life-extending antioxidants linked to lower risks of heart disease and Alzheimer's, its caffeine masks adenosine - the brain's signal for sleep pressure. Startling research shows that caffeine consumed even six hours before bed can strip away an hour of sleep, often without the sleeper ever realizing their sleep quality has been compromised.This episode outlines practical rules for timing and dosage based on your unique biology. Discover the "caffeine curfew," why genetics make many of us slow metabolizers, and how decaf provides an "antioxidant orchestra" without the sleep-disturbing "brass trumpet." By mastering these principles, you can enjoy the significant long-term health benefits of the bean while safeguarding the deep, restorative sleep necessary for your brain and body to recover every night.Please note that Matt is not a medical doctor, and none of the content in this podcast should be considered medical advice in any way, shape, or form, nor prescriptive in any way.One of today's sponsors, David, is a revolutionary new protein bar that boasts an unbeatable ratio: 28g of protein and 0g of sugar in just 150 calories. Incredibly satiating with six amazing flavors, it's perfect for muscle health. Visit davidprotein.com/mattwalker and buy 4 cartons to get a 5th FREE!Another partner, LMNT, offers a science-based electrolyte drink with no sugar or artificial ingredients. Try their Lemonade Salt flavor! Get eight free sample packs with any order at drinklmnt.com/mattwalker. Stock up now on this summery flavor!As always, if you have thoughts or feedback you'd like to share, please reach out:Matt: Instagram @drmattwalker, X @sleepdiplomat, YouTube https://www.youtube.com/@sleepdiplomat
Episode Summary: In this enlightening conversation, Dr. Majid Fotuhi discusses the multifaceted nature of brain health, emphasizing the importance of understanding different types of intelligence, the power of practice and learning, and the interconnectedness of brain and body health. He addresses common misconceptions about memory and cognitive function, the impact of negative memories, and the role of genetics versus lifestyle in Alzheimer's disease. Dr. Fotuhi provides practical tips for enhancing brain function and encourages a holistic approach to maintaining cognitive health throughout life.Chapters00:00 Exploring Brain Intelligence03:02 The Power of Practice and Learning06:01 Understanding Memory and Cognitive Function08:39 The Interconnectedness of Brain and Body12:02 Overcoming Negative Memories and Trauma14:47 Alzheimer's Disease: Genetics vs. Lifestyle17:59 Holistic Approaches to Brain Health20:54 The Role of Stress and Emotional Well-being23:51 Practical Tips for Enhancing Brain Function26:55 Final Thoughts on Brain Health and LongevitySponsors: FATTY15 OFFER: Fatty15 is on a mission to replenish your C15 levels and restore your long-term health. You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/KIMBERLY and using code KIMBERLY at checkout.USE LINK: fatty15.com/KIMBERLY LMNTOFFER: Right now, for my listeners LMNT is offering a free sample pack with any LMNT drink mix purchase at DrinkLMNT.com/FEELGOOD. That's 8 single serving packets FREE with any LMNT any LMNT drink mix purchase. This deal is only available through my link so. Also try the new LMNT Sparkling — a bold, 16-ounce can of sparkling electrolyte water.USE LINK: DrinkLMNT.com/FEELGOOD Dr. Majid Fotuhi Resources: Book: The Invincible Brain: The Clinically Proven Plan to Age-Proof Your Brain and Stay Sharp for Life Website: neurogrow.com Social: YouTube @Dr. Majid Fotuhi Bio: Dr. Fotuhi earned his PhD in Neuroscience from Johns Hopkins University in 1992 and his Medical Degree from Harvard Medical School in 1997. Currently, he serves as an adjunct professor at the Mind/Brain Institute at Johns Hopkins University, while also teaching at George Washington University and Harvard Medical School.With 37 years of experience in teaching, clinical practice, and neuroscience research, Dr. Fotuhi has pioneered a multidisciplinary approach to enhancing brain vitality and cognitive performance at any age. His groundbreaking “Brain Fitness Program” combines a comprehensive baseline “Brain Portfolio” assessment with 12 bi-weekly brain training sessions. This program targets lifestyle optimization and cognitive stimulation to improve memory, focus, and overall brain health. Dr. Fotuhi's program has delivered measurable success for patients dealing with memory loss due to aging, concussions, and ADHD, as documented in several peer-reviewed journals. He is also the author of three books, including the highly acclaimed Boost Your Brain: The New Art and Science Behind Enhanced Brain Performance. Recognized as one of the leading experts in memory and successful aging, Dr. Fotuhi has delivered lectures at academic institutions and major organizations in over 20 countries – including a TEDx presentation in the Philippines. Passionate about sharing the latest discoveries in the field of brain rehabilitation and neuroplasticity, he has been featured in interviews with more than 50 prominent media outlets in the United States and around the globe.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Dr Steve and Dr Scott discuss: 1. Scott literally wrote this in the show notes: "Something about dabblecom, was napping" 2. Is there a difference between medical school today and in the past? 3. Virus talk 4. TCM and Ayurvedic 5. How sensitive is the human touch 6. Alzheimer's and beta amyloid, cancer protection, all kinds of sh!t Please visit: STUFF.DOCTORSTEVE.COM (for dabblegames at cost and more!) simplyherbals.net/cbd-sinus-rinse (the best he's ever made. Seriously.) instagram.com/weirdmedicine x.com/weirdmedicine fightthedabbler.com (help Karl and Shuli win their LOLsuit) youtube.com/@weirdmedicine (click JOIN and ACCEPT GIFTED MEMBERSHIPS. Join the "Fluid Family" for live recordings!) CHECK OUT THE ROADIE COACH stringed instrument trainer! roadie.doctorsteve.com (the greatest gift for a guitarist or bassist! The robotic tuner!) see it here: stuff.doctorsteve.com/#roadie GET YOUR TROY SMITH ARTWORK FROM "WET BRAIN: THE GAME OF TROLLS AND LOSERS!" get it here: dabblegames.myshopify.com (a most-fun party game!) each shipment comes with some awful tchotchke! Also don't forget: Cameo.com/weirdmedicine (Book your old pal right now because he's cheap! "FLUID!") Most importantly! CHECK US OUT ON PATREON! ALL NEW CONTENT! Robert Kelly, Mark Normand, Jim Norton, Gregg Hughes, Anthony Cumia, Joe DeRosa, Pete Davidson, Geno Bisconte, Cassie Black ("Safe Slut"). Stuff you will never hear on the main show ;-) Learn more about your ad choices. Visit podcastchoices.com/adchoices
Gotham has never yet seen this level of heroism. Jim and A.Ron emerge from the Batcave to give you the final totals and update on the success of the Groundhog Day 24 hour marathon! The guys reminisce about the prep, the event, the aftermath, and go over the community's favorite moments from the stream. Then, we bring on Lainie from The Cure Alzheimer's Fund to accept the donation for CureAlz and talk about the latest findings in Alzheimer's research! GHD MEMES!!!! Monorail SQUEEZE! BatJim squeezes for Gotham: https://www.twitch.tv/baldmove/clip/HappyPreciousPlumCoolCat-3Xjd782EtBEalngL A.Ron squeezing: https://www.twitch.tv/baldmove/clip/FurtivePlainJackalDatBoi-TuDXlU7S4aNuLGDY Batman and Bane stop by the studio… A.Ron's Sleep Paralysis Demon: https://www.twitch.tv/baldmove/clip/AntediluvianAlluringBarracudaMau5-KgUKa1VC18MbR5NK Batman on dating: https://www.twitch.tv/baldmove/clip/SillyFancyWitchItsBoshyTime-nYjEyraT-m0PlEoW Pow and Wack: https://www.twitch.tv/baldmove/clip/PlausibleCloudyDragonfruitPanicVis-ZIxBPDJVfHeaLTCW Bane stops by: https://www.twitch.tv/baldmove/clip/CogentPopularMetalDBstyle-EFVdmfLZXAnSQHkW The Rikerer: Jim's Travel Riddle: https://www.twitch.tv/baldmove/clip/EasyFancyHareMoreCowbell-zCjURCzU-vXafVj1 Deadliest Juice Riddle https://www.twitch.tv/baldmove/clip/StrangeHilariousWerewolfHassaanChop-rMtxv8U8SN-UH35a Random The finish line is crossed! GOOOOOOALLLLL! https://www.twitch.tv/baldmove/clip/BillowingFreezingPhoneBibleThump-zsdXGqmFsoPqlxfE Dr. Rhythm https://www.twitch.tv/baldmove/clip/GenerousTallNewtAllenHuhu-ukE8ThCQO3XglxqP Eric's pushing Clayface outta the bat cave: https://www.twitch.tv/baldmove/clip/AwkwardEnjoyableDillHassaanChop-kZ5GXCe4EnLWkMxk The 3am surprise (NSFW!!): https://www.twitch.tv/baldmove/clip/PleasantSpeedyHamburgerWoofer-YbVlv7884BpGrSme Brother-in-Law BBQ incoming!: https://www.twitch.tv/baldmove/clip/FaintCuteStorkArsonNoSexy-DsHRK_OLAzt2uO_T Don't spark my battits: https://www.twitch.tv/baldmove/clip/DeliciousDependableMarjoramTBTacoLeft-nAk_Uj4UPOX4w-ip You summoned Rick for this?: https://www.twitch.tv/baldmove/clip/CalmGiftedBubbleteaJebaited-1QWnGoS0McP43iRH Save one baby…: https://www.twitch.tv/baldmove/clip/TameSmallMacaroniMrDestructoid-sIJmw3IjT5HlX6zP Boston Batman: https://www.twitch.tv/baldmove/clip/PoliteStylishPheasantPlanking-QgXwkFv9gMtZf-D6 Sad lion noises: https://www.twitch.tv/baldmove/clip/OriginalDelightfulMulePJSugar-xXOICpEQnSsbHLHr Batnipple Talk: https://www.twitch.tv/baldmove/clip/RelievedLittleZebraTF2John-wSc2UHfXkdW6GqWC Jim grows out some Batbangs: https://www.twitch.tv/baldmove/clip/FreezingJoyousTaroImGlitch-nFqQDTRLJMj9Oam_ Jim has enhanced virility: https://www.twitch.tv/baldmove/clip/CrazyLongHawkCclamChamp-fmApg1cfXzjLXtPw A.Ron feels great https://www.twitch.tv/baldmove/clip/BetterLittleReubenDancingBanana-CAzR6GxJnI7o5mXx Cold Rolled Steel: https://www.twitch.tv/baldmove/clip/ProductiveSpotlessClintArsonNoSexy-AzN2KayCv35Pf-Dg The T is for tongue: https://www.twitch.tv/baldmove/clip/NeighborlyCredulousPenguinDAESuppy-doq6xg7oNCIh8f54 On-air prostate exams?: https://www.twitch.tv/baldmove/clip/CrackyHorribleBubbleteaSoonerLater-nhaW3R8aDzT9TQgm Hey there! Check out https://support.baldmove.com/ to find out how you can gain access to ALL of our premium content, as well as ad-free versions of the podcasts! Join the Club! Join the discussion: Email | Discord | Reddit | Forums Follow us: Twitch | YouTube | Twitter | Instagram | Facebook Leave Us A Review on Apple Podcasts Learn more about your ad choices. Visit megaphone.fm/adchoices
Hey Transformers, as we close out our longevity series, I'm bringing back a powerful TYM Classic — and I'm re-airing this episode very intentionally. When we recorded this episode on epigenetics, it completely reframed the way I think about health, longevity, and regenerative health. It wasn't just science — it was empowerment. So many of us have been told that our genes determine our future. That if something “runs in the family,” it's inevitable. But this discussion opened up a different narrative — one rooted in research, lifestyle choices, and the power we actually have to influence how our genes express themselves.Summary: Myrna Young engages in an enlightening conversation with Dr. Matthew Dawson about the transformative influence of epigenetics on health. Understanding the pivotal role of epigenetics in shaping our DNA destiny, Dr. Dawson elaborates on how lifestyle choices markedly influence gene expression, highlighting that genetic predispositions only contribute a fraction to overall health outcomes compared to epigenetic factors. The episode delves into the importance of personalized healthcare plans, as demonstrated through case studies such as Dr. Dawson's mother, who effectively managed her risk of Alzheimer's through personalized lifestyle adjustments. Key Takeaways:Epigenetic Influence: Lifestyle choices, such as diet and exercise, are crucial in turning genes on or off, significantly affecting health outcomes.Personalized Healthcare: Utilizing genomics and epigenetics can lead to tailored healthcare plans that can mitigate genetic risks.Biological Age Understanding: Biological age tests offer a more precise measure of health and longevity than chronological age.Resource Utilization: Tools like Wild Health and True Diagnostic can aid in personalized health planning and prolonging health span.Sponsors of this episode: NOCD: If you're struggling with OCD or unrelenting intrusive thoughts, NOCD can help. Book a free 15-minute call to get started: Because healing the mind can truly change your life. https://learn.nocd.com/transform Spark Energy + Focus is offering 30% off and free shipping. Go to drinkspark.com and use code TRANSFORM at checkout. See this video on The Transform Your Mind YouTube Channel https://www.youtube.com/@MyhelpsUs/videosTo see a transcripts of this audio as well as links to all the advertisers on the show page https://myhelps.us/Follow Transform Your Mind on Instagram https://www.instagram.com/myrnamyoung/Follow Transform Your mind on Facebookhttps://www.facebook.com/profile.php?id=100063738390977Please leave a rating and review on iTunes https://podcasts.apple.com/us/podcast/transform-your-mind/id1144973094 https://podcast.feedspot.com/personal_development_podcasts/ For sponsored Brand interviews and sponsorship inquires please visit Partner With The Transform Your Mind Podcast | Myrna Young Life Coach
Your keys aren't lost. Your mind isn't going. And no, that's not Alzheimer's. Dr. Majid Fotuhi, Adjunct Professor, Johns Hopkins University & author of The Invincible Brain, busts the biggest myth in women's brain health: that the fog, the forgetfulness, and the "wait, why did I walk in here?" moments of perimenopause are a sign of something sinister. Spoiler: they're not. And your brain? It can literally grow. From the surprising science of how walking three times a week can give you a measurably bigger brain, to why your hearing aid might be the best thing you ever do for your memory, Dr. Fotuhi gives us proof that midlife isn't a decline — it's a new childhood. And this time, you're in charge. Episode Overview (timestamps are approximate): (0:00) Intro/Teaser (5:00) Why Perimenopause Causes Brain Fog (8:00) Estrogen & How Hormones Affect Memory (13:00) Exercise Is the #1 Pillar of Brain Health (16:00) Exercise That Grows Your Brain (21:00) Brain Fog vs. Alzheimer's (26:00) Your Genes Are Not Your Destiny (30:00) Medications & Hearing Loss (43:00) Beyond IQ: The 30 Forms of Intelligence (50:00) Brain Training & Neuroplasticity (1:01:00) The After-Party with Dr. Stephanie Resources mentioned in this episode: https://drstephanieestima.com/podcasts/ep458 We couldn't do it without our sponsors: QUALIA CREATINE+ - If you want to feel stronger, sharper, and more resilient, Qualia's Creatine+ is my recommendation.Go to https://qualialife.com/better and use code BETTER to save up to 50%, plus an additional 15% off. COZY EARTH - Cozy Earth helps you feel better by keeping your temperature perfect overnight to facilitate deep restorative sleep. Head to https://cozyearth.com and use my code BETTER for up to 20% off. TROSCRIPTIONS - There's a completely new way to optimize your health. Give it a try at https://troscriptions.com/BETTER or enter BETTER at checkout for 10% off your first order. PIQUE LIFE - If you want to redefine your evening ritual and still feel like yourself the next day, you can get 10% off for life. Yes, for life at https://piquelife.com/better YOUNG GOOSE - More resilient. More hydrated. More responsive. This is skin quality skincare. Go to https://younggoose.com/better and use code BETTER for 10% off your first purchase ****************************P.S. When you're ready, here are two ways Dr. Stephanie can help you:Subscribe: The Mini Pause — My weekly newsletter packed with the most actionable, evidence-based tools for women 40+ to thrive in midlife.Build Muscle: LIFT — My progressive strength training program designed for women in midlife. Form-focused, joint-friendly, and built for real results. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Dr. Centor discusses the diagnosis of Alzheimer disease with Dr. Gayatri Devi.
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El Código Electoral ya va camino a La Fortaleza tras la aprobación con el rechazo de las minorías. ¿Qué cambia realmente y por qué la oposición denuncia un proceso unilateral?Netflix se retira oficialmente de la carrera por Warner Bros. después de que la oferta de Paramount se disparara. Analizamos qué significa esta movida para la industria del entretenimiento y quién termina ganando poder.Además, discutimos el aumento dramático en el costo de la vivienda en Puerto Rico: precios suben 21.5% mientras los salarios no siguen el ritmo.En el chit chat:Zohran Mamdani, su “fake newspaper” y cómo terminó encantando a Trump para prometer un acuerdo masivo de vivienda.Y en el Patreon Exclusive:Un update rápido de Ciary que no podíamos dejar fuera.-Si quieres escuchar los bloques completos, sin cortes y antes que nadie:
In this episode, Ron Simmons interviews Nate Sheets, who is a fifth-generation Texan, entrepreneur, and founder of Nature Nate's Honey. Nate shares how an Air Force upbringing, a life-changing mission trip to Venezuela, and years in full-time Christian ministry shaped his faith and calling. He tells the story behind evangelism tools like the EvangeCube and the I Am Second movement, reflects on walking through his mother's battle with Alzheimer's and cancer, and explains why he's now running for Texas agriculture commissioner to support farmers, protect local agriculture, and improve the quality of the food we eat. Visit Nate's website here: https://natesheets.com Check out I Am Second here: https://www.iamsecond.com Share the Arrows 2026 is on October 10 in Dallas, Texas! Tickets are on sale now at: https://sharethearrows.com Buy Allie's book "Toxic Empathy: How Progressives Exploit Christian Compassion": https://www.toxicempathy.com — Timecodes: (00:00) Intro (00:50) Nate's Background (04:40) Working in Ministries (08:20) Campaigning for Texas Agriculture Commissioner (09:10) Ron's Analysis — Related Episodes: Ep 1307 | This Is What AOC Means When She Says "Worker Focused Trade" | Ron Simmons https://podcasts.apple.com/us/podcast/relatable-with-allie-beth-stuckey/id1359249098?i=1000750786201 Ep 1300 | Was the Government Shutdown a Win or Loss for Trump? | Ron Simmons https://podcasts.apple.com/us/podcast/relatable-with-allie-beth-stuckey/id1359249098?i=1000748662175 Ep 1293 | Ron Simmons | Can Trump Use the Insurrection Act Against Minnesota Mayhem? https://podcasts.apple.com/us/podcast/relatable-with-allie-beth-stuckey/id1359249098?i=1000746486355 Ep 1286 | Maduro Detained, Minnesota ICE Altercation, Can Trump Save Single-Family Homes? | Ron Simmons https://podcasts.apple.com/us/podcast/relatable-with-allie-beth-stuckey/id1359249098?i=1000744608458 — Buy Allie's book "You're Not Enough (and That's Okay): Escaping the Toxic Culture of Self-Love": https://www.alliebethstuckey.com Relatable merchandise: Use promo code ALLIE10 for a discount: https://shop.blazemedia.com/collections/allie-stuckey Learn more about your ad choices. Visit megaphone.fm/adchoices
Send a textOn this powerful episode, Cornell Bunting sits down with Darlande Jean-Charles, RN, BSN — National IV Instructor, founder of Nurse U2 Wellness, and a nurse on a mission to redefine personalized care.Darlande's journey is one of resilience and purpose. After immigrating from Haiti to America at 13 — not speaking English and facing bullying while adjusting to a new life with her adopted parents — she found strength through adversity. Caring for her adopted mother during her battle with cancer became the moment that revealed her calling.Her nursing career began in 2013 as a Home Health Aide while pursuing her LPN. She went on to specialize in Alzheimer's and dementia care, earned her RN in 2018, and later became a Director of Nursing leading teams of over 90 staff in Assisted Living and Memory Care. Determined to grow, she expanded into hospital care in Med-Surg, Telemetry, and the Emergency Room, earning her Bachelor of Science in Nursing in 2024. That same year, she became a certified National IV Instructor, blending her love for teaching with clinical excellence.Today, through Nurse U2 Wellness, Darlande provides concierge wellness and IV hydration services that combine professionalism, compassion, and convenience — empowering clients to feel their best wherever they are.This conversation is about faith, resilience, education, and answering your calling. Tune in now — link in bio Listen. Share. Be inspired. Support the showThank you for tuning in with EHAS CLUB - Stories to Create Podcast
Intelligence Unshackled: a show for people with brains (a Brainjo Production)
In this episode, we discuss a study published in PLOS One that compared living brain tissue to post-mortem brain tissue and found dramatic molecular differences between the two. The findings raise serious questions about decades of Alzheimer's research built on post-mortem analysis and may help explain why pharmaceutical treatments for the disease have been so disappointing Study: A Study of RNA Splicing and Protein Expression in the Living Human Brain -------------- To submit a question for us to answer on the podcast, go to brainjo.academy/question. To subscribe to the free Better Brain Fitness newsletter, join us when we record live, and get our Guide and Checklist to essential blood tests and nutrients, go to: betterbrain.fitness. To learn more about how you can boost brain fitness with neuroscience-based musical instruction, head to brainjo.academy. Intro and Outro music composed and produced by Julienne Ellen.
Today, how the brain harnesses immune cells to clear burned out fats during sleep: does this protect from Alzheimer's disease? Also, the nutrient-rich guano of seabirds that shaped society in ancient Peru, fast footage reveals how kangaroos hop faster at no extra energy cost, and how horses whinny! Like this podcast? Please help us by supporting the Naked Scientists
A study published in Nature Communications, published Feb 19, 2026, found that “pregnancy physically alters a woman's brain, with a second pregnancy bringing even more profound effects.” The researchers “performed brain scans on 110 women. Some were first-time mothers, others second-time moms, and some nulliparous women. Results showed that during a first pregnancy, the greatest changes occur in the structure and activity of the ‘default mode network' – the brain system responsible for self-reflection and mind wandering. Are these changes bad? Are they associated with long term hard? Are they adaptive? It's a complex question, with real answers. Listen in for details.1. Straathof, M., Halmans, S., Pouwels, P.J.W. et al. The effects of a second pregnancy on women's brain structure and function. Nat Commun 17, 1495 (2026). https://doi.org/10.1038/s41467-026-69370-82. de Lange AG, Kaufmann T, van der Meer D, et al. Population-Based Neuroimaging Reveals Traces of Childbirth in the Maternal Brain. Proceedings of the National Academy of Sciences of the United States of America. 2019.3. Aleknaviciute J, Evans TE, Aribas E, et al.)Long-Term Association of Pregnancy and Maternal Brain Structure: The Rotterdam Study. European Journal of Epidemiology. 2022.4. Jung JH, Lee GW, Lee JH, et al. Multiparity, Brain Atrophy, and Cognitive Decline. Frontiers in Aging Neuroscience. 2020.5. Hu A, Xiong L, Wei H, et al. Association of Menarche, Menopause, and Reproductive History With Cognitive Performance in Older US Women: A Cross-Sectional Study From NHANES 2011-2014. BMC Public Health. 2025.6. Orchard ER, Ward PGD, Sforazzini F, et al. Relationship Between Parenthood and Cortical Thickness in Late Adulthood. PloS One. 20207. Hoekzema E, Barba-Müller E, Pozzobon C, et al. Pregnancy Leads to Long-Lasting Changes in Human Brain Structure. Nature Neuroscience. 2017.8. de Lange AG, Barth C, Kaufmann T, et al. Women's Brain Aging: Effects of Sex-Hormone Exposure, Pregnancies, and Genetic Risk for Alzheimer's Disease. Human Brain Mapping. 2020.Visit our SPONSOR's LINK to learn more about the Hemorrhage view CS Drape: https://www.perspectivemedical.org/
Robert Horry and the crew kick off Shoot Around episode 124 with jokes and impressions before jumping into a pop quiz: the only NBA player to win a scoring title, rebounding title, blocks title, Rookie of the Year, MVP, Defensive Player of the Year, an NBA championship, and an Olympic gold medal—revealed to be David Robinson. The conversation shifts to Spurs talk, with Horry pushing back on claims that he hates San Antonio, explaining his take on why he doesn’t have Wemby as his MVP and naming his MVP as “Brown,” while still praising the Spurs, Pop, and the 2005 championship team. They discuss the Chicago Bears potentially moving about 25 miles south to Hammond, Indiana, while likely keeping the “Chicago Bears” name, comparing it to New York teams playing in New Jersey and noting Indiana’s willingness to fund a new stadium. The group also talks about which franchises should never move, highlighting the St. Louis Cardinals and San Diego Padres, and briefly noting the Braves’ move within the Atlanta area. In NBA rules talk, they react to Paul Pierce’s idea of an LED three-point line that turns on and off during games, calling it too gimmicky and better suited to celebrity or All-Star-style events. The episode also covers UFL rule changes, including a four-point field goal for kicks over 60 yards and banning punts once a team crosses midfield, with the hosts debating whether the NFL might adopt similar ideas and joking about how it would affect Super Bowl squares. Off the court, they break down MLB Players Association executive director Tony Clark resigning after an internal investigation revealed an improper relationship with his sister-in-law, and they react to Mad Dog Russo’s defense while debating how personal life should intersect with employment consequences. They wrap with viral oddities and childhood stories: a 92-year-old woman with Alzheimer’s climbing a seven-foot nursing home gate in 24 seconds, a 12-year-old in North Carolina driving himself to school with a fictitious plate after missing the bus, and the hosts sharing the dumbest things they did as kids—stealing church money for cookies, kicking a hole through a bedroom door, and a messy food fight that led to “double dip” punishments. 00:00 Friday Cold Open 01:25 Wild Twitter Grab Bag 01:40 NBA Trivia Stumper 03:22 Spurs Fans Clapback 05:38 Bears Moving to Indiana 07:17 Teams That Shouldn’t Move 08:43 LED Three Point Line 10:01 UFL Rule Experiments 12:14 Tony Clark Scandal 15:21 92 Year Old Gate Escape 17:11 Kid Drives To School 19:11 Cookie Money Confession 20:42 Foot Through The Door 22:29 Epic Food Fight Fallout 23:46 Double Dip Whoopings
What if your bleeding gums are silently damaging your heart and brain? NYU professor and medical pioneer Dr. Jonathan Levine reveals the truth about the oral-systemic superhighway, how mouth bacteria trigger Alzheimer's, the "small jaw" epidemic sabotaging your sleep, and his 3-minute routine for ultimate longevity!Dr. Jonathan Levine is a world-renowned prosthodontist, NYU clinical professor, and inventor with over 29 patents. He is the founder of GLO Science and a leading pioneer in oral-systemic medicine, dedicated to bridging the gap between dental health and longevity.Products 528 Innovations Lasers NeuroSolution Full Spectrum CBD NeuroSolution Broad Spectrum CBD NeuroSolution Stimpod STEMREGEN® Learn MoreFor more information, resources, and podcast episodes, visit https://tinyurl.com/3ppwdfpm
Much more talk and calls on the marijuana psychosis topic from Dr. Sal, Local Father Joe Henry discusses his son Franklin, his mutation which is widely studied, could lead to treatment breakthroughs for Alzheimers, Parkinsons, MS and more.
You're not "just tired." In this episode of The Confidence Doc®, Dr. Rukmini (Vinaya) Rednam sits down with sleep psychologist Dr. Daniela Marchetti to break down what's really happening when we don't sleep; and why high-achieving women struggle the most. They discuss: • What actually happens in your brain while you sleep • Why insomnia becomes a learned pattern • CBT for insomnia vs sleeping medications • The real impact of scrolling at night • Sleep regularity and women's hormones • Sleep, Alzheimer's risk & longevity • Practical steps to improve sleep starting tonight If you're exhausted but wired… If you rely on caffeine to survive… If you think sleep is optional… This episode may completely change your perspective. Because confidence isn't just built in the OR or the boardroom; it's built at night.
Can the aging brain still make new neurons? A landmark 2026 Nature study analyzed 355,997 human hippocampal nuclei using single-nucleus RNA sequencing and ATAC sequencing. Neurogenesis persists into adulthood—but chromatin accessibility collapses early in Alzheimer's disease. SuperAgers showed a 2.5-fold increase in immature neurons and a preserved resilience signature. Epigenetics may be the earliest battlefield in cognitive decline.
In this episode, recorded live at AHR Expo 2026, Bryan sits down with Louise from UEi (United Electronics Inc.) for an in-depth conversation about one of the most underestimated dangers in the HVAC trade: carbon monoxide. Rather than treating CO as just another checkmark on a safety list, Bryan and Louise dive into the full history of the gas — all the way back to early publications from 1922 and 1923 that were already studying the effects of low-level CO exposure. One of the most fascinating takeaways from their discussion is just how long the industry has known about the dangers of carbon monoxide, yet how frequently it remains misunderstood, misdiagnosed, and overlooked on the job site. Louise breaks down the science behind CO poisoning in a way that is both accessible and eye-opening. Unlike high-level acute poisoning — where symptoms are immediately obvious — low-level, chronic carbon monoxide exposure is an entirely different beast. It can mimic the flu, chronic headaches, early-onset Alzheimer's, and even heart attack symptoms. Because CO is colorless, odorless, and tasteless, it is notoriously difficult to diagnose, and victims often have no idea what is causing their illness. Compounding the problem is the cumulative nature of CO toxicity: the gas builds up in the bloodstream over time and can linger in the body for days, months, or even years after exposure ends. Bryan draws an entertaining but sobering historical connection between the prevalence of carbon monoxide poisoning during the Victorian era — when gas lamps were common inside homes — and the widespread reports of ghost sightings, fugue states, fainting spells, and the spiritualist movement of the time. It was almost certainly CO poisoning, not the paranormal. The conversation then shifts to practical, on-the-job guidance for technicians and contractors. Bryan and Louise walk through the proper process for combustion analysis: starting your analyzer outside in fresh air, identifying test ports on furnaces, boilers, and water heaters, and understanding what readings at steady state actually mean. They emphasize that CO production is not limited to furnaces alone — ranges, ovens, dryers, fireplaces, water heaters, and even propane-powered forklifts are all legitimate sources. One of the most critical points they make is that carbon monoxide hazards are often intermittent and condition-dependent. A system can appear to be working perfectly during one visit and be producing dangerous levels the next time a door is closed or a vent is accidentally blocked. Visual inspection, awareness of combustion air sourcing, and thoughtful analysis are just as important as having the right instruments. On the product side, Louise introduces two exciting new offerings from UEI. The first is the UEI Clip, a compact personal CO detector that clips onto a bag, belt, or lanyard, activates automatically at 20 ppm, and is designed as a set-it-and-forget-it safety device with a two-year sealed battery lifespan. Priced under $100, it is an affordable way to outfit an entire team with a baseline layer of personal protection. The second highlight is the new High Accuracy Clamp Meter (HAC), a commemorative product celebrating the United States' 250th anniversary. This meter excels at wattage measurement — particularly with low-draw ECM blower motors where most meters fall short — and Bluetooth integration with MeasureQuick is on the horizon. Louise also walks through UEI's revamped combustion analyzer recertification program, UEI Service Plus, which offers same-day turnaround on standard recertifications at their Indianapolis facility, extended warranties with each annual service, and transparent, upfront pricing directly on their website. Topics Covered The history of carbon monoxide research dating back to publications from 1922 and 1923, and a 1923 patent for a hot water heater that sparked a friendly debate between Bryan and Louise about terminology. How low-level, chronic CO exposure is underdiagnosed and can mimic conditions like the flu, chronic headaches, early-onset Alzheimer's, and heart attack symptoms — and why CO builds up cumulatively in the bloodstream. The fascinating historical theory connecting widespread Victorian-era reports of ghosts, fugue states, and fainting spells to chronic carbon monoxide poisoning from indoor gas lamps. CO safety thresholds: residential standard (9 ppm), World Health Organization guideline (4 ppm), first responder evacuation threshold (35 ppm), and how UL-rated home alarms may not trigger until 70 ppm sustained for 1–4 hours. Sources of CO that technicians often overlook, including ovens, ranges, dryers, fireplaces, water heaters, propane forklifts, generators, and vehicles idling near garages. Proper combustion analysis procedure: starting the analyzer outside in ambient air, identifying or installing test ports, running tests at steady state, and interpreting O2, CO, and stack temperature readings. Industry CO standards for furnaces: official standard (400 ppm), HRI recommendation (200 ppm), industry best practice (100 ppm), and modern high-efficiency benchmarks (50 ppm or less). How combustion air sourcing — and changes to it (new roofs, blocked vents, swapped doors) — is one of the most commonly missed risk factors for CO production. Why even "heat pump markets" like Florida still need combustion analysis, since over 90% of homes have at least one fuel-fired appliance. Introduction of the UEi Clip personal CO detector: set-and-forget, activates at 20 ppm, sealed 2-year battery, priced under $100, and its unexpected popularity among refrigeration technicians. Introduction of the UEi High Accuracy Clamp Meter (HAC) commemorative edition: exceptional accuracy at low current draws (ideal for ECM blower motors), full accessory kit included, and upcoming measureQuick Bluetooth integration. UEi's Service+ combustion analyzer recertification program: same-day turnaround at their Indianapolis lab, extended warranty with each annual service, prepaid UPS shipping labels, and transparent pricing on their website. A brief spotlight on UEi as a family-owned business founded by Michael Kane's parents, with their own manufacturing operations in the UK and Korea. Learn more about UEi's new and longstanding products, as well as the Service+ guarantee, at https://ueitest.com/. Have a question that you want us to answer on the podcast? Submit your questions at https://www.speakpipe.com/hvacschool. Purchase your tickets or learn more about the 7th Annual HVACR Training Symposium at https://hvacrschool.com/symposium. Subscribe to our podcast on your iPhone or Android. Subscribe to our YouTube channel. Check out our handy calculators here or on the HVAC School Mobile App for Apple and Android.
Have you ever wondered what the dead really want us to know, or what they wish they'd done differently while they were alive? Are you waiting for the "perfect time" to follow your dreams, find love, or start that new career? Are you ready to hear the desperate message the other side has for you about living while you still can? Michael welcomes back Matt Fraser, America's top medium and New York Times bestselling author, to discuss the profound wisdom found in his new book, Don't Wait Till You're Dead. After more than 10,000 readings, Matt reveals that the departed have one primary message: your life has purpose, and you are the only one putting limits on your potential. Discover why the spirit world is remarkably calm even when we are "freaking out," how your hardest life chapters are actually your greatest teachers, and the shocking truth about who your guardian angel really is. This isn't just about the afterlife; it's a masterclass in reclaiming your "God-given gifts" to create a more meaningful and limitless life right here, right now. Key Topics: The Limitless Life: Why your loved ones in spirit want you to know it is never too late to meet your soulmate, land your dream job, or raise a family. The Wisdom Download: How souls "upload" earthly knowledge and "download" divine teachings to become wiser on the other side. From EMT to Medium: Matt shares his personal "101" journey of overcoming childhood bullying and silencing his gifts before embracing his true mission. The Truth About Regrets: Why souls look back with clarity on their mistakes and how they use that reflection to become spirit guides for the living. Guardian Angels vs. Departed Loved Ones: The surprising distinction between those you knew on Earth and the angelic beings who have never walked the physical plane. Navigating "Red Lights": Why closed doors and "construction zones" in your life are often signs from your angels that you are being redirected for your own protection. The Soulmate Connection: A mind-bending look at why we have multiple life partners but only one true soulmate across all of eternity. Cloud Backups for the Soul: Why the Alzheimer's or dementia of this world cannot touch the vivid, clear memories stored eternally in the soul. This is a call to stop the internal war and start the conversation. As Matt explains, conversation is a two-way street; when you begin talking to your loved ones in spirit, you open the door to a team of people cheering you on from heaven. Join the Inspire Nation Soul Family!
Don’t plan for just one side of retirement. Design Your Life in Retirement. Join our small group coaching program beginning in April. Learn more here. Very Early Registration Discount ends on March 1st. Sign up here. ___________________________ What if the biggest risk in retirement isn't the market — but misunderstanding your own goals? As you approach retirement, the questions shift. It's no longer just “How much have I saved?” It becomes, “When do I want the freedom to retire?” “How much risk do I really need to take?” And perhaps most importantly — “What is my money for?” Today, I'm joined by financial planner Zach Morris for a candid conversation about risk tolerance versus risk capacity, sequence of return risk, working one more year, helping family, and why having a 100% probability of financial success might actually mean you're leaving life on the table. If you're within five years of retirement — or wondering whether you're truly ready — this episode will help you think differently about risk, purpose, and pulling the trigger. Zach Morris, CFP joins us from Atlanta. __________________________ Bio Having traveled to over 35 countries, Zach is a believer in Ralph Waldo Emerson's statement that Life is about the journey, not the destination. Being a CERTIFIED FINANCIAL PLANNER® provides Zach the opportunity to help clients define and realize their journey, and co-founding Paces Ferry Wealth Advisors, an independent firm, allows the freedom to define the client experience along the way. Previously, Zach was a partner in The Diamond Morris Group and a Financial Advisor with J.P. Morgan Securities, a wealth management division of J.P. Morgan. Before becoming a Financial Advisor, Zach started as an Associate with the firm in 2011, where he developed skills for building lasting relationships with clients. Later, Zach developed and oversaw a training and mentorship program for J.P. Morgan Associates. Zach supports a number of organizations including Alzheimer's Association, Georgia Chapter, The Shepherd Center, Crohn's & Colitis Foundation of America, and NewStory. Zach received a B.S. in finance, with a minor in economics, from Elon University in North Carolina. He was a member of The Kappa Alpha Order and has served on the board of the Elon Alumni Association's Atlanta chapter. Zach speaks Spanish and is an Atlanta native. He and his wife live in West Midtown's Underwood Hills neighborhood and his parents and two of his three sisters and their families live nearby. In his spare time, Zach golfs, plays tennis, rides his mountain bike and travels. _____________________________ For More on Zach Morris, CFP Paces Ferry Wealth Advisors Zach Morris, CFP® You Tube channel ______________________________ Podcast Conversations You May Like How to Live a Meaningful Life – Dave Evans Re-Visioning Retirement – Susan Reid, PhD Retire with Purpose – Cesar Aguirre ______________________________ About The Retirement Wisdom Podcast There are many podcasts on retirement, often hosted by financial advisors with their own financial motives, that cover the money side of the street. This podcast is different. You'll get smarter about the investment decisions you'll make about the most important asset you'll have in retirement: your time. About Retirement Wisdom I help people who are retiring, but aren't quite done yet, discover what's next and build their custom version of their next life. A meaningful retirement doesn't just happen by accident. Schedule a call today to discuss how the Designing Your Life process created by Bill Burnett & Dave Evans can help you make your life in retirement a great one — on your own terms. About Your Podcast Host Joe Casey is an executive coach who helps people design their next life after their primary career and create their version of The Multipurpose Retirement.™ He created his own next chapter after a 26-year career at Merrill Lynch, where he was Senior Vice President and Head of HR for Global Markets & Investment Banking. Joe has earned Master's degrees from the University of Southern California in Gerontology (at age 60), the University of Pennsylvania, and Middlesex University (UK), a BA in Psychology from the University of Massachusetts at Amherst, and his coaching certification from Columbia University. In addition to his work with clients, Joe hosts The Retirement Wisdom Podcast, ranked in the top 1% globally in popularity by Listen Notes, with over 1.6 million downloads. Business Insider recognized Joe as one of 23 innovative coaches who are making a difference. He's the author of Win the Retirement Game: How to Outsmart the 9 Forces Trying to Steal Your Joy. ______________________________ Wise Quotes On The One More Year Trap “Sometimes it's just one more year because they don't know what the next step is…If somebody is working one more year and they have 100% probability of success — they’re not just leaving money on the table, they’re leaving life on the table.” On Risk “Risk is invisible… you can have a risk tolerance today, but once you hit that maximum threshold, it can very quickly become uncomfortable.” On Retirement Planning “You don't want to go into retirement with unfulfilled expectations. You want to go into retirement knowing what to expect.” _____________________________
Send a textCaregiving can feel like carrying a secret storm—so many decisions, so much love, and a kind of grief that doesn't wait for goodbye. We open up about the real weight caregivers hold and how faith, practical wisdom, and honest reflection can turn that weight into steadier steps. Rayna shares her journey through years of caring for a mom and dad with Alzheimer's, naming the hidden losses, the relentless pressure to get it right, and the slow, surprising growth that follows when we surrender what we were never meant to carry.Across this conversation, we name layered grief—the missed moments, shifting roles, and the parts of yourself that go quiet when life gets hard. We also unpack pressure: family expectations, cultural shoulds, medical complexity, and the inner critic that never sleeps. You'll hear how to distinguish conviction from condemnation so you can be responsible without living as if you must control every outcome. Scripture anchors the path, reminding us that Jesus wept, that grace meets weakness, and that the Lord is close to the brokenhearted.We then turn to growth without platitudes. Growth doesn't cancel pain, but it does shape patience, endurance, compassion, and a deeper dependence on God. You'll learn how to honor parents without losing yourself, why boundaries are part of true honor, and how love can be both tender and wise. Rayna offers five practical steps you can use today—naming losses, releasing borrowed pressure, asking for specific help, building a small rhythm of rest, and redefining success around presence and the next right step. We close with reflective questions to help you process what hurts and notice where hope is already at work.If this conversation helps you breathe a little easier, share it with another caregiver who needs encouragement. Subscribe for new episodes and leave a review so more caregivers can find these stories of hope. Your next right step might start here.
What if one targeted supplement could do more for your healing than twenty random ones?When you're navigating chronic or serious illness, it's easy to accumulate bottles, protocols, and conflicting advice. But more supplements do not necessarily equal more healing. If you're facing cancer, autoimmune disease, neurological illness, heart disease, or another chronic diagnosis, this episode will help you move from confusion to clarity.Together we explore the science behind building a supplement plan that works with your body. We discuss why testing matters, how mitochondrial dysfunction shows up across chronic illness, why gut health determines absorption, and how to layer support without exhausting your system.In this episode, you'll learn:Why correcting deficiencies should always come before adding “extra” supplementsHow to identify which healing systems need support first, such as mitochondria, inflammation regulation, or gut stabilityWhy starting slowly improves tolerance, absorption, and long-term successHow to build a clear supplement hierarchy so each product has a purposeA simple framework for creating a routine that feels sustainable instead of stressfulListen now to learn how to simplify your supplement routine and support your healing with intention.DisclaimerThis podcast is for educational purposes only and does not provide medical advice. Always consult your licensed healthcare provider before starting or adjusting supplements, especially if you are taking medications or undergoing active treatment.This podcast explores science and stories related to cancer, dementia, Alzheimer's, MS, ALS, heart disease, autoimmune conditions, chronic illness, integrative medicine, and remission — offering grounded hope and practical tools to support resilience and healing.
Vele duizenden Nederlanders krijgen komende jaren de diagnose dementie. De teller staat op 320 duizend patiënten en in 2040 gaat het waarschijnlijk om een half miljoen. Wat betekent dat voor de maatschappij en voor naasten? Redacteur Kim Bos nam voor NRC de ziekte onder de loep, van eerste klachten tot aan het levenseinde.NRC maakte ook de serie 'Hans' over leven met alzheimer. Hier te beluisteren.Gast: Kim BosPresentatie: Bram EndedijkRedactie: Esmee DirksEindredactie: Tessa ColenMontage: Gal Tsadok-HaiCoördinatie: Ilse EshuisProductie: Rhea StroinkHeb je vragen, suggesties of ideeën over onze journalistiek? Mail dan naar onze redactie via podcast@nrc.nl.Zie het privacybeleid op https://art19.com/privacy en de privacyverklaring van Californië op https://art19.com/privacy#do-not-sell-my-info.
The Real Truth About Health Free 17 Day Live Online Conference Podcast
Learn why oils, animal products, and processed foods increase Alzheimer's risk—and how nuts, seeds, and plant-based fats protect cognitive function. #BrainFood #DementiaPrevention #WholeFoodNutrition
A Texas company sold a list of 435,000 Alzheimer's patients to anyone with a credit card. The fine? $45,000. I break down why HIPAA doesn't protect your family and what you can do right now.Plus, the Windows printer setting that's been driving you crazy for years and the sneaky calendar scam hiding on your iPhone. Learn more about your ad choices. Visit megaphone.fm/adchoices
An estimated 500,000 people are diagnosed with Alzheimer's disease in the United States each year, but the causes and mechanisms of the condition remain a neurological mystery. A recent study looked at the role of variants in a gene called APOE in Alzheimer's, and found that while it's not a simple determinant of developing the disease, that one gene seems to play a significant role in promoting disease risk. Researchers hope work like this could point to new areas to study and even potential treatments. Epidemiologist Dylan Williams joins Host Ira Flatow to explain the findings and discuss the challenges in tracing a complex disease to its roots. Guest: Dr. Dylan Williams is a principal research fellow in molecular and genetic epidemiology at University College London. Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.
Ginny Yurich sits down with neurologist and neuroscientist Dr. Majid Fotuhi to flip the script on what most of us assume about memory: it isn't something you either “have” or “lose”—it's a skill you can build. Drawing from decades of work with brain health, ADHD, concussion recovery, and cognitive decline, Dr. Fotuhi explains why everyday forgetfulness is often normal (and not an automatic sign of Alzheimer's), then gives a clear, doable framework for getting sharper at any age through his five pillars of brain health—exercise, sleep, nutrition, stress reduction, and brain training. You'll hear why movement supercharges the brain, why racquet sports and “thinking + motion” activities are especially powerful for kids and adults, how to make names and information stick by adding emotion and play, what's actually happening during menopause brain fog, and why optimism and purpose aren't just nice ideas—they're linked to real changes in the brain. This episode is practical, hopeful, and immediately motivating—you'll finish it feeling like your brain isn't fragile… it's trainable. So exciting!! Get your copy of The Invincible Brain here Learn more about Dr. Fotuhi and all he has to offer here Learn more about your ad choices. Visit megaphone.fm/adchoices
If you've ever cared for someone with Alzheimer's—or loved someone who has—you know the quiet heartbreak of watching a person you cherish slowly fade, even while they are still physically present. It's a journey marked by grief, exhaustion, and a longing for strength that often feels just out of reach. In today's episode, storyteller Jennifer Roberts from our West Cobb community outside of Atlanta, Georgia, shares her experience of walking alongside her father-in-law as her mother-in-law battled Alzheimer's. With honesty and tenderness, Jennifer reflects on the weight of caregiving, the sorrow woven into the disease, and the unexpected ways God met her family in the middle of it all. Her story is a powerful reminder that when God calls us into a difficult season, He also equips us with perseverance, sustains us with His presence, and leads us forward with hope, joy, and strength. If you are a caregiver—or know someone who is—this is a story you won't want to miss, and one you'll want to share. VERSE OF THE WEEK: "Consider it pure joy, my brothers and sisters, whenever you face trials of many kinds, because you know that the testing of your faith produces perseverance. Let perseverance finish its work so that you may be mature and complete, not lacking anything." James 1:2-4 CHALLENGE OF THE WEEK: If you know someone who is caretaking for a loved one, reach out to them this week by sending an encouraging message, making a call to check in on them, or offering to be of some assistance. ________________________________________________ Listen to Jennifer Roberts' sisters' story from season 8- Ep. 300- Laurel Henson: "The Providence of God: A Story of Love After Loss." Listen to a similar story: Ep. 299- Kenzie Hightower: "When We Can't, He Can: A Sister's Story of Support." Download a phone background of the weekly verse HERE! Give to StoryTellers Live in honor of Jennifer and any of our past storytellers! Join us "In the Room" on Patreon to access new stories straight from our live gatherings around the country! Join us for our Stories of Hope luncheon on March 11th in Birmingham! Shop for our When God Shows Up Bible Study series~ Stories of Hope, Stories of Freedom, Stories of Faith Are you interested in one-on-one coaching with our very own Robyn Kown!? Click HERE! Check out all of our live speaking engagement opportunities on our website. Sign up to receive StoryTellers Live's weekly newsletter for updates and details on our live gatherings.
Discover all of the podcasts in our network, search for specific episodes, get the Optimal Living Daily workbook, and learn more at: OLDPodcast.com. Episode 3306: Dr. Jenny Brockis explores the powerful brain-boosting potential of turmeric, highlighting how curcumin, the active compound in the spice, may help reduce inflammation, clear harmful amyloid plaques, and support cognitive health. Backed by compelling studies from UCLA and the University of Michigan, she reveals how a simple dietary habit like eating curry could play a role in protecting against Alzheimer's and age-related memory decline. Read along with the original article(s) here: https://drjennybrockis.com/2010/6/23/why-eating-curry-is-good-for-your-brain/ Quotes to ponder: "Curcumin reduced the number of plaques in the rat brains by up to 80% at low dose and the rats given the curcumin performed better on spatial memory tests compared to the control group." "Vitamin D also strongly stimulated the uptake and absorption of amyloid beta by the macrophages in the majority of patients." "Curcumin can cross the blood brain barrier and binds to amyloid protein fragments, which can then no longer clump together to form plaques." Episode references: Alzheimer's Disease and Inflammation (Dr. Milan Fiala Research): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2814545/ Learn more about your ad choices. Visit megaphone.fm/adchoices
Episode 26-8 Do You Need A Healing? Start Here… Millions of Americans are currently dealing with some kind of chronic condition. Conditions such as arthritis, heart disease, cancer, Type 2 Diabetes, Hashimoto's, IBS, Alzheimer's, headaches, eczema, erectile dysfunction, fibromyalgia, etc. Fortunately, these conditions can usually be improved through natural measures. The question is HOW? HOW does one get their body to heal itself naturally? While there are many different strategies to consider… strategies that differ based upon the involved condition… there is ONE thing that each strategy has in common. One thing that will help set you on the right path with regard to YOUR healing journey: Your starting point. It's true. No matter what health issue you're seeking to heal from… there is ONE place for you to start and it's here: With a blood test. On this episode I go into great depth regarding the specific blood tests I recommend for anyone seeking to heal their body from a chronic disease. Specifically, I talk about how the root CAUSE of most chronic conditions correlates with something that is "off" in one or more of these blood tests. Or, stated in a slightly different way: The root CAUSE of most chronic conditions is something that will show up in one or more of these blood tests. This is incredibly valuable because once you identify what is "off" in your blood work you can then implement strategies to correct it. This, in turn, will place your body in an environment that's conducive to healing. Give this episode a good listen if you're serious about having your body heal itself naturally. And, as always, be sure to share it with a friend. Thanks! ———————- Want to learn more? Continue the conversation regarding this episode, and all future episodes, by signing up for our daily emails. Simply visit: GetHealthyAlabama.com Once there, download the "Symptom Survey" and you will automatically added to our email list. ———————- Also, if you haven't already, we'd appreciate it if you'd subscribe to the podcast, leave a comment and give us a rating. (Thanks!!!) * This podcast is for informational and educational purposes only. It is not intended to diagnose or treat any disease. Please consult with your health care provider before making any health-related changes.
In this episode of The Golden Gang, host Ryan sits down with Colleen Gill, Walk Manager for the Alzheimer's Association in South Jersey. Colleen shares what truly drives the Walk to End Alzheimer's — a grassroots community effort that raises over $100 million annually and funds everything from research to a 24-hour helpline for families.She also tells the moving story of Billy, a walk participant whose early diagnosis and enrollment in a clinical trial has him thriving years later — living proof that the work is making a difference. If your family has been touched by Alzheimer's, this one's for you.
If you're carrying quiet fear because Alzheimer's has touched your family — or you're struggling with brain fog and worried about your brain health — this episode is for you.In this episode, Amy breaks down the 5 biggest mistakes women make with Alzheimer's prevention and brain health, plus one bonus mistake that ties them all together. These aren't obscure errors. They're rooted in outdated beliefs — the same ones most of our parents held — that research has now proven wrong.You'll learn:Why waiting for symptoms is the most expensive strategy there is — and why the menopause transition is your most critical window for preventionHow your genes inform your risk but don't determine your outcome — and the 8-factor RESTORED Protocol that puts the levers back in your handsWhy supplements can't do the job of a strong lifestyle foundationHow chronic stress damages the hippocampus — and what a sustainable recovery plan looks like during menopauseWhat the glymphatic system is and why disrupted sleep is one of the most under-recognized risks for cognitive declineWhy the knowing-doing gap — not lack of information — is the real reason most women aren't protecting their brains (with exercise as the perfect example)Take the ‘Is It Just Brain Fog?' QuizDownload my FREE Brain Health GuideSchedule your Breakthrough Roadmap session with AmyRESOURCES: Book a FREE Discovery Call with Amy Order Amy's book Thoughts Are Habits Too: Master Your Triggers, Free Yourself From Diet Culture, and Rediscover Joyful Eating. Schedule your Breakthrough Roadmap session with Amy Follow Amy on Instagram @amylangcoaching Follow Amy on Facebook @amylangcoaching Subscribe to Amy's YouTube channel @happyandhealthywithamy
Discover all of the podcasts in our network, search for specific episodes, get the Optimal Living Daily workbook, and learn more at: OLDPodcast.com. Episode 3306: Dr. Jenny Brockis explores the powerful brain-boosting potential of turmeric, highlighting how curcumin, the active compound in the spice, may help reduce inflammation, clear harmful amyloid plaques, and support cognitive health. Backed by compelling studies from UCLA and the University of Michigan, she reveals how a simple dietary habit like eating curry could play a role in protecting against Alzheimer's and age-related memory decline. Read along with the original article(s) here: https://drjennybrockis.com/2010/6/23/why-eating-curry-is-good-for-your-brain/ Quotes to ponder: "Curcumin reduced the number of plaques in the rat brains by up to 80% at low dose and the rats given the curcumin performed better on spatial memory tests compared to the control group." "Vitamin D also strongly stimulated the uptake and absorption of amyloid beta by the macrophages in the majority of patients." "Curcumin can cross the blood brain barrier and binds to amyloid protein fragments, which can then no longer clump together to form plaques." Episode references: Alzheimer's Disease and Inflammation (Dr. Milan Fiala Research): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2814545/ Learn more about your ad choices. Visit megaphone.fm/adchoices
This is a recap of the top 10 posts on Hacker News on February 24, 2026. This podcast was generated by wondercraft.ai (00:30): IDF killed Gaza aid workers at point blank range in 2025 massacre: ReportOriginal post: https://news.ycombinator.com/item?id=47136179&utm_source=wondercraft_ai(01:56): I'm helping my dog vibe code gamesOriginal post: https://news.ycombinator.com/item?id=47139675&utm_source=wondercraft_ai(03:22): OpenAI, the US government and Persona built an identity surveillance machineOriginal post: https://news.ycombinator.com/item?id=47140632&utm_source=wondercraft_ai(04:48): Firefox 148 Launches with AI Kill Switch Feature and More EnhancementsOriginal post: https://news.ycombinator.com/item?id=47133313&utm_source=wondercraft_ai(06:14): Mac mini will be made at a new facility in HoustonOriginal post: https://news.ycombinator.com/item?id=47143152&utm_source=wondercraft_ai(07:41): Blood test boosts Alzheimer's diagnosis accuracy to 94.5%, clinical study showsOriginal post: https://news.ycombinator.com/item?id=47132388&utm_source=wondercraft_ai(09:07): Discord cuts ties with identity verification software, PersonaOriginal post: https://news.ycombinator.com/item?id=47136036&utm_source=wondercraft_ai(10:33): I pitched a roller coaster to Disneyland at age 10 in 1978Original post: https://news.ycombinator.com/item?id=47136604&utm_source=wondercraft_ai(11:59): How we rebuilt Next.js with AI in one weekOriginal post: https://news.ycombinator.com/item?id=47142156&utm_source=wondercraft_ai(13:26): Open Letter to Google on Mandatory Developer Registration for App DistributionOriginal post: https://news.ycombinator.com/item?id=47139765&utm_source=wondercraft_aiThis is a third-party project, independent from HN and YC. Text and audio generated using AI, by wondercraft.ai. Create your own studio quality podcast with text as the only input in seconds at app.wondercraft.ai. Issues or feedback? We'd love to hear from you: team@wondercraft.ai
Brain Talk | Being Patient for Alzheimer's & dementia patients & caregivers
This interview is brought to you in partnership with Eisai and is part of the Journey to Diagnosis series.Eisai: https://www.eisai.com/index.htmlJourney to Diagnosis: https://beingpatient.com/journey-to-diagnosis/ What are the early signs of primary progressive aphasia (PPA)?In this Being Patient Live Talk, Samuel Valverde and his wife, Heather, share their journey to a diagnosis of primary progressive aphasia, a form of cognitive impairment that affects language and communication.Samuel Valverde is a Desert Storm combat veteran and former police chief in Waelder, Texas, who built his life around discipline, service, and staying sharp under pressure. But over time, subtle changes began to appear — missed court dates, forgotten details, and increasing difficulty with focus, planning, and speech.In 2022, while being treated for PTSD, Samuel's psychologist noticed changes that seemed to go beyond trauma. After months of testing — including cognitive evaluations, speech therapy, MRIs, and a PET scan — Samuel was diagnosed at age 53 with primary progressive aphasia (PPA).In this conversation with Being Patient's Mark Niu, Samuel and Heather talk openly about:Recognizing the early warning signs of PPAThe road to diagnosisHow PPA affects speech and daily lifeThe emotional impact on the whole familyAdjusting roles as a couple after diagnosisFinding resilience, support, and hopeIf you or someone you love is living with PPA, young-onset Alzheimer's, or another form of dementia, this conversation offers insight, support, and practical perspective.Visit Being Patient for more Alzheimer's and brain health coverage: https://www.beingpatient.com/Follow Being PatientTwitter: / being_patient Instagram: / beingpatientvoices Facebook: / beingpatientalzheimers LinkedIn: / being-patient Being Patient is an editorially independent journalism outlet covering brain health, cognitive science, and neurodegenerative diseases. Our Live Talk series features interviews with experts and people living with dementia.
Conscious Caregiving with L & L is "Tackling the Tough Conversations." The topic of this episode is "The Future of AlzAuthors" featuring hosts Lori La Bey and Lance A. Slatton. About Lori La Bey: Lori La Bey is the founder of Alzheimer's Speaks and is co-founder of Dementia Map global resource directory and the co-host of Conscious Caregiving with L & L. Lori's mother who lived with dementia for 30 years. Her goal has always been to shift dementia care from crisis to comfort around the world. She offers a variety of free resources to educate, empower, connect, and decrease stigmas; helping families and professionals live graciously alongside dementia. Lori is an international speaker known for her multiple platforms and training programs. Connect with Lori La Bey: Official Website: https://alzheimersspeaks.com/ Official Dementia Map Website: https://www.dementiamap.com/ About Lance A. Slatton - known as "The Senior Care Influencer"": Known as "The Senior Care Influencer" Lance is a Writer, Author, Influencer, and Healthcare professional with over 20 years in the healthcare industry. Lance A. Slatton is a senior case manager at Enriched Life Home Care Services in Livonia, MI. He is also host of the award winning podcast & YouTube channel All Home Care Matters and Co-Host of Conscious Caregiving with L & L with Lori La Bey along with The Care Advocates and The Caregiver's Journal. Lance is also the new President of AlzAuthors. Lance's book, "The All Home Care Matters Official Family Caregivers' Guide" was the recent recipient of the 2024 International Impact Book Awards. Connect with Lance A. Slatton - "The Senior Care Influencer": Official Website: https://www.lanceaslatton.com Official Website for All Home Care Matters: https://www.allhomecarematters.com Official Website for AlzAuthors: https://www.alzauthors.com Lance A. Slatton and Lori La Bey Co-Host and Produce Conscious Caregiving with L & L. Visit their website at: https://consciouscaregivingll.com/ To learn more about Lance A. Slatton and Lori La Bey you can visit their websites.
The surgeon who spent 12 to14 hours a day in the operating room developed diabetes, uncontrolled high blood pressure, and an autoimmune disease that was eating away at his skull and it forced him to confront what medical school never taught him about actually staying healthy. I sat down with Dr. Darshan Shah, board-certified surgeon, founder of Next Health (one of the largest longevity clinic networks in America), and a doctor who had to reverse his own chronic disease to understand the massive gap between Western medicine and the science of health. We explore why surgeons and physicians become some of the sickest people in healthcare, how functional medicine differs from what you learn in medical school, why biomarker testing matters more than your doctor's "you're fine" assessment, and what root cause medicine actually looks like in practice. Dr. Shah also breaks down the AI revolution happening in cardiovascular imaging with Cleerly scans, how his new AI health dashboard reads your bloodwork and medical records to give you proactive guidance, why Yamanaka factors could regenerate damaged nerves in the brain, and what the future of personalized, preventive medicine looks like when you combine AI with real biological data. Reduce your risk of Alzheimer's with my science-backed protocol for women 30+: https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ TOPICS DISCUSSED 00:00 Intro: The surgeon who developed the diseases he was treating 01:17 From trauma surgeon to longevity doctor: Dr. Shah's journey 04:18 Autoimmune disease, diabetes, and high blood pressure in a surgeon 10:30 Western medicine vs. the science of health 18:45 Why doctors don't learn prevention in medical school 35:20 Next Health clinics and democratizing longevity medicine 52:40 Biomarker testing and why "your labs are normal" is dangerous 01:03:52 AI health dashboard: uploading bloodwork and getting proactive guidance 01:06:45 Cleerly scans and reversing cardiovascular disease with AI imaging 01:10:08 Yamanaka factors, nerve regeneration, and the future of brain health _______ Thank you to our sponsors Function Health: https://www.functionhealth.com/louisanicola Timeline Mitopure: http://timeline.com/NEURO Ka'Chava: https://kachava.com and use code NEURO for 15% off your first order Wayfair: https://www.wayfair.com/ Fenix: https://www.fenixhealthscience.com/ Arey: https://arey.com/ and use code NEURO _______ I'm Louisa Nicola - clinical neurophysiologist - Alzheimer's prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer's risk - and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices
Conversations about brain health have been dominated by a competing mix of fatalism and over-promising, with aging framed as inevitable decline and "brain optimisation" sold through weak evidence. So how should we think about cognition across the lifespan? In this episode, we explore the idea that neuroplasticity does not disappear in adulthood, but instead continues to respond, for better or worse, to repeated behaviours and exposures. Much of what is labelled age-related cognitive decline may in fact reflect an accumulation of modifiable risk factors. We also dig into how to critically evaluate brain-health claims and how lifestyle pillars such as exercise, sleep, diet, stress reduction and cognitive training fit into a coherent framework. The discussion extends to emerging multimodal intervention programs, their promising signals and their clear limitations, and to a broader, multifactorial view of Alzheimer's disease that moves beyond a narrow amyloid-centric model. Finally, we examine the role of genetics, including ApoE4, and why genetic risk does not equate to biological destiny, even later in life. Dr. Majid Fotuhi is a neurologist and an adjunct professor at the Johns Hopkins Mind/Brain Institute. He earned his medical degree from Harvard Medical School and completed a Ph.D. in neuroscience at Johns Hopkins University. That was followed by internship and neurology residency at Johns Hopkins Hospital. Timestamps [03:41] Understanding neuroplasticity [05:22] Risk factors for cognitive decline [07:07] Evidence-based interventions for brain health [09:37] The five pillars of brain health [10:42] Dr. Fotuhi's multimodal program [19:09] Measuring cognitive function [24:43] The role of amyloid and tau in Alzheimer's [27:53] Genetics and lifestyle in brain health [30:03] Debunking myths and overhyped claims [36:08] Key ideas segment (premium subscribers only) Related Resources Go to episode page (with links to studies mentioned) Join the Sigma email newsletter for free Subscribe to Sigma Nutrition Premium Enroll in the next cohort of our Applied Nutrition Literacy course Dr. Fotuhi's book: The Invincible Brain
In this episode, I talk with Dr. Tommy Wood about how to protect and strengthen brain health across the lifespan—how overstimulation, chronic stress, and not giving your brain time to rest and recover undermines focus and productivity, and why restructuring your workday, prioritizing sleep, and building in real cognitive breaks can help you think more clearly and perform better. We discuss how the balance of stimulus, supply, and support shifts as we age, why retirement and prolonged illness can accelerate cognitive decline without ongoing challenge, and how physical activity, deep work, and continued learning help maintain function and even build “crystallized intelligence”—wisdom—later in life. We also get into genetic risk and why it’s largely a probability game where lifestyle can stack the deck in your favor; the powerful role of social connection and helping others in reducing dementia risk; how to use digital tools for real connection instead of passive consumption; and the cognitive effects of substances like nicotine, alcohol, cannabis, and stimulants. Dr. Tommy shares practical strategies—from structuring your day around focused work and restorative breaks to picking hobbies that challenge your brain—as well as simple ways to maintain cognitive function, extend the time you stay sharp, and lower the likelihood of decline over your life. TIMESTAMPS: Tommy Wood's new book explains the environmental impact on your brain health. [01:07] In adults over 40, dementia is the number one health concern. [07:21] Why haven't we done a better job of understanding the brain's neurological disease? [13:28] Studies have shown that an older adult learning a new language or musical instrument, experiences significant changes in the structure of the brain. [20:45] Failure is the primary driver of neuroplasticity. [21:35] If you do one of two activities such as attending lectures, writing, classes, volunteering, sports and such, you are best protected from dementia. [ 26:00] What are the three S's that are the key to long-term brain health and disease prevention? [29:08] Metabolic disease like high blood pressure is a significant risk factor for dementia. [35:13] People who are stressed usually don't give their brain time to recover. [36:03] Some people do have genetic influence and possibly have a higher risk that they can learn to work with. [38:33] It's estimated that 45 to 70 ish percent of dementias are preventable. [39:53] We can eliminate this accelerated decline that we are seeing around us by hitting the checkpoints like move, nourish, stimulate, connect and adapt. [47:06] The social connection is terribly important. [47:43] The areas of the brain that are most susceptible to decreases in function as we age, are the areas of the brain that are negatively impacted by being socially isolated. [51:27] What is the impact of the digital world that surrounds us? What about smoking and alcohol? [52:26] Marijuana use definitely has an effect on brain. [01:02:46] If someone only has a small amount of time to learn these things, what would be the tips you would give them? [01:07:34] LINKS: Brad Kearns.com BradNutrition.com - 20% OFF Your First Order! B.rad Superdrink – Hydrates 28% Faster than Water—Creatine-Charged Hydration for Next-Level Power, Focus, and Recovery B.rad Whey Protein Superfuel - The Best Protein on The Planet! Brad’s Shopping Page BornToWalkBook.com B.rad Podcast – All Episodes Peluva Five-Toe Minimalist Shoes Dr. Tommy Wood Instagram @drtommywood The Stimulated Mind: Future-proof your Brain Podcast with Wood: Metabolic Efficiency Podcast with Wood: Sensible Healthy Living Podcast with Wood: Beauty of Not Always Optimizing Nourish Balance Thrive Dr.TommyWood.com We appreciate all feedback, and questions for Q&A shows, emailed to podcast@bradventures.com. If you have a moment, please share an episode you like with a quick text message, or leave a review on your podcast app. Thank you! Check out each of these companies because they are absolutely awesome or they wouldn’t occupy this revered space. Seriously, I won’t promote anything that I don't absolutely love and use in daily life: B.rad Nutrition: Premium quality, all-natural supplements for peak performance, recovery, and longevity; including the world's highest quality whey protein! Get 20% OFF your first order! Peluva: Comfortable, functional, stylish five-toe minimalist shoe to reawaken optimal foot function. Use code BRADPODCAST for 15% off! Get Stride: Advanced DNA, methylation profile, microbiome & blood at-home testing. Hit your stride the right way, with cutting-edge technology and customized programming. Save 10% with the code BRAD. Online educational courses: Numerous great offerings for an immersive home-study educational experience Primal Fitness Expert Certification: The most comprehensive online course on all aspects of traditional fitness programming and a total immersion fitness lifestyle. Save 25% on tuition with code BRAD! See omnystudio.com/listener for privacy information.
In this solo episode, Dr. Fiona Lovely delivers an urgent and empowering message about brain health that every woman needs to hear. She breaks down a brand-new research review examining how menopause specifically impacts the female brain, revealing why postmenopausal women account for more than 60 percent of those living with Alzheimer's disease. Rather than leaving listeners with frightening statistics, Dr. Lovely transforms this information into actionable knowledge, explaining exactly how declining estrogen, progesterone, and testosterone along with inadequate nutrition, stress and aging create a perfect storm for neurodegeneration through increased inflammation, and breakdown of the protective blood-brain barrier. What makes this episode particularly valuable is Dr. Lovely's practical guidance on modifiable risk factors that women can address starting today. She explores the critical connection between the gut microbiome and brain defense systems, offering specific nutritional strategies that support cognitive health during the menopausal transition. Listeners will learn why good protein intake becomes non-negotiable at midlife, which foods deliver the omega-3s, antioxidants, and flavonoids brains desperately need, and how to identify ultra-processed and nutrient-void foods that may be undermining our efforts. Dr. Lovely also addresses timely concerns about popular weight loss medications, explaining why adequate nutrition must remain the priority even when appetite is suppressed. The episode concludes with fascinating news from the research front: hormone replacement therapy has now been shown to reverse many of the inflammatory changes that occur with hormone decline, stabilizing the blood-brain barrier and offering genuine neuroprotective benefits. For any woman who has ever wondered whether her brain health is within her control, this episode provides helpful answers and practical tools to make a meaningful difference. For easy reference, Dr. Lovely has compiled the products mentioned in this episode right here: Jaspr - air filtration Ultrahuman - sleep and recovery biometrics ring Chilipad - temp controlled mattress pad Apollo neuro - vagus nerve modulating tool AG1 - complete vitamins and mineral supplement Just Thrive - the best probiotic Thank you to our sponsors for this episode: ❤️Berkeley Life is a health brand that helps women feel vibrant by addressing the crucial role nitric oxide and circulation play in daily wellness, especially around menopause. If you're navigating perimenopause and want to support your cardiovascular health and your menopause transition proactively, Berkeley Life's Menopause and Heart Health support is designed exactly for this moment. You can learn more and explore their supplements at BerkeleyLife.com and get 20% off your first order (use code LOVELY)
For the Good of the Public brings you news and weekly conversations at the intersection of faith and civic life. Monday through Thursday, The Morning Five starts your day off with scripture and prayer, as we also catch up on the news together. Throughout the year, we air limited series on Fridays to dive deeper into conversations with civic leaders, thinkers, and public servants reimagining public life for the good of the public. Today's host was Michael Wear, Founder, President and CEO of the Center for Christianity and Public Life. Thanks for listening to The Morning Five! Please subscribe to and rate The Morning Five on your favorite podcast platform. Learn more about the work of the Center for Christianity and Public Life at www.ccpubliclife.org. Today's scripture: Matthew 9:35-38 and 10:1-11 (ESV) News sources: https://www.nytimes.com/live/2026/02/23/weather/nyc-snow-storm https://apnews.com/article/mexico-jalisco-cartel-mencho-sheinbaum-trump-226e50edc33f981d5d6509acc7021ae5 https://www.wsj.com/politics/national-security/pentagon-flags-risks-of-a-major-operation-against-iran-1c7e9939?mod=hp_lead_pos2 https://www.washingtonpost.com/national-security/2026/02/23/dan-caine-iran-risk-trump/ https://www.washingtonpost.com/health/2026/02/21/alzheimers-busy-mind-study-delay/ Join the conversation and follow us at: Instagram: @michaelwear, @ccpubliclife Twitter: @MichaelRWear, @ccpubliclife and check out @tsfnetwork Music by: King Sis #politics #faith #prayer #scripture #blizzard #Mexico #cartel #Iran #Alzheimers Learn more about your ad choices. Visit megaphone.fm/adchoices
Dr. Tony Wyss-Coray, PhD, is a professor of neurology at Stanford School of Medicine who is discovering factors present in young blood and in exercised blood that can improve brain, heart and other organ health. We discuss how different organs age at different rates and how to accurately measure biological aging. We also discuss the specific proteins found in blood when we are young and that are increased by things such as exercise, sunlight exposure, short-term fasting, specific foods and social connection that can significantly increase vitality, restore youthful functioning of the brain and body and potentially increase lifespan. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman David: https://davidprotein.com/huberman LMNT: https://drinklmnt.com/huberman ROKA: https://roka.com/huberman Function: https://functionhealth.com/huberman Timestamps (00:00:00) Tony Wyss-Coray (00:03:00) Young vs Old Animals, Age-Related Disease (00:06:35) Blood Biomarkers, Young vs Old Humans, Alzheimer's Disease (00:12:50) Sponsors: David & LMNT (00:15:28) 'Young Blood' Factors, Rejuvenation, Stem Cells (00:20:15) Blood Banking; Dracula (00:23:10) Rates of Aging in Organs, Age Gap & Disease Risk; Risk Profiles & Therapies (00:33:02) NAD Levels & Aging, NMN Supplements (00:36:44) Vitality vs Longevity; Periods of Accelerated Aging (00:43:17) Sponsors: AG1 & Roka (00:45:22) Sunlight; Youthful Blood Factors, Exercise & Brain Function, Fasting (00:51:25) Exercise, Injury & Inflammation (00:56:18) Pro-health Factors, Klotho, GDF11, Stem Cell Injection Risk (01:02:35) Platelet-Rich Plasma (PRP); Exosomes (01:05:43) Smoking, EMFs, Plastics, Long-Term Accumulation, Fresh Foods, Organic Food (01:11:28) Sponsor: Function (01:13:16) Intermittent Fasting, Long-Term Fasting, Snacking (01:19:07) Sleep; Cerebrospinal Fluid (CSF) Factors & Cognitive Function (01:24:44) Exercise Type & Longevity; Exercise Enjoyment (01:32:02) Lifestyle Factors & Alzheimer's Risk; Cognitive Exercise; Chocolate (01:37:05) Alcohol & Social Connection; US vs European Food Culture (01:40:50) Deliberate Deep Breathing; Wearables, Sunlight & Artificial Light (01:49:13) Future Projects (01:56:40) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices