Podcasts about Parkinson

This week on Parky Profiles, we're speaking to Andy Cassy, friend of the podcast, fellow Parky ping-pong player, and the only Brit to take part in what has been described as 'a landmark first-in-human clinical trial' in the search for a Parkinson's cure. Andy underwent stem cell surgery in 2024 as part of said trial, organised by one of our other Parky Profile guests, Professor Roger Barker. We spoke to Andy then, and got back in touch recently to see how his view on his experience may have changed. While the dopamine-replacement surgery is not the 'holy grail', he says, it seems to have reduced our guest's symptoms somewhat. Andy shares with us why his surgery was so good - and perhaps what ground is yet to be covered. Movers & Shakers is brought to you in partnership with Cure Parkinson's.Presented by Rory Cellan-Jones, Gillian Lacey-Solymar, Mark Mardell, Paul Mayhew-Archer and Sir Nicholas MostynProduced by Lulu Goad and Ewan Cameron for PodotMusic by Alex Stobbs Hosted on Acast. See acast.com/privacy for more information.

Your gut lining rebuilds itself every five days — faster than any other tissue in your body — and that turnover rate is either your best defense or your biggest vulnerability, depending on what you're doing to it. In the final episode of this series with stem cell scientist and STEMREGEN founder Christian Drapeau, Eric Malzone digs into why the intestinal lining is "the most fragile and vulnerable part of your body," how estrogen withdrawal at menopause quietly wrecks gut repair, and why Christian believes the real story of aging isn't inflammation or free radicals — it's a failure of the body's own repair system. They also get into a jaw-dropping 1940s case study on gut bacteria and psychosis, the specific bacteria linked to autoimmune disease and diabetes, and why Christian thinks "stem cells bring cure" is the hardest sentence in modern medicine. Key Takeaways

As co-founder of the CeleBRation Choir at the University of Auckland's Centre for Brain Research back in 2009, music therapist Alison Talmage knows the benefits of a good sing-a-long. She's written a handbook to help other people launch similar initiatives in their communities, so people dealing with serious brain conditions like dementia, strokes and Parkinson's Disease can get together in choirs. It's an initiative that's seen big benefits overseas, as the physical and social effects of singing in groups can help ease the symptoms of neurological conditions. But unlike similar choirs in other countries, Talmage leads a group of singers across a broad swathe of ages and different circumstances.

I'm really hoping that Dolly enjoys the triple D's in the title, she was and will forever be an icon musically, philanthropically, and surgically. This episode is dedicated to the incredible women, incredible people, who, like Dolly, live their truth and uplift facts yet do not shy away from speaking passionately and genuine emotion. Sure, it may take “a lot of money to look that cheap,” but there's not enough cash in the world that could purchase Dolly Parton's integrity and integrity IS the purest expression of beauty.  You will be missed dearly, Miss Parton. We will always love you. Please take some time to check out Dolly Parton's Imagination Library, it's celebrating 31 years and 300,000,000+ books gifted (free of charge) to children from birth to age five in the US, Canada, UK, Australia, and Republic of Ireland! Visit: https://imaginationlibrary.com/  Support the show (and your chest): Save 20% Off Honeylove by going to honeylove.com/SCHAUER ! #honeylovepod #sponsored #ad  Books: Living Well With Orthostatic Intolerance: A Guide to Diagnosis and Treatment - Peter C. Rowe, MD Most Delicious Poison: The Story of Nature's Toxins - From Spices to Vices - Noah Whiteman Clean: The New Science of Skin and the Beauty of Doing Less - James Hamblin  Scent: A Natural History of Fragrance - Elise Vernon Pearlstine Doctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer's - Charles Piller  Sources: Dolly Parton, Queen of Country Music, Dies at 80 https://variety.com/2026/music/news/dolly-parton-dead-dies-country-music-1236842727/ Can You Smell a Disease? Exploring the Link Between Odor and Sickness https://myacare.com/blog/can-you-smell-a-disease-exploring-the-link-between-odor-and-sickness Human perception of Parkinson's disease body odor in comparison to the volatile organic compounds of Parkinson's disease https://www.sciencedirect.com/science/article/pii/S1353802024011039 Food Recalls: FreshRecall https://freshrecall.com/ Has images for easy reference, what class of recall, if its ongoing, recalls for different states as well as hazard type Includes recalls by allergen The data is sourced from the FSIS USDA and the FDA RecallScope https://recallscope.com/ App available in the App Store and on google play Allows you to track products and scan VINs and barcodes as well as get alerts The app is free but there are ads. If you would like to send me any additional information on any topic, whether you think it sounds related or like something I should know, please feel free. I love listening and learning. Wishing all of you the best, please treat yourself kindly. Learn more about your ad choices. Visit podcastchoices.com/adchoices

What if Alzheimer's doesn't begin when you start forgetting names or struggling with memory but decades earlier, when subtle changes are happening in your metabolism, inflammation, and brain?   With Alzheimer's in my own family, this conversation with Dr. David Perlmutter felt especially personal. Dr. Perlmutter is a board-certified neurologist, six-time New York Times bestselling author, and one of the leading voices challenging how we think about brain health and cognitive decline. His new book, Brain Defenders, explores emerging research around microglia — the immune cells of the brain — and why they may hold an important key to protecting our brains as we age.   We dive into why Dr. Perlmutter believes we need to start thinking about Alzheimer's prevention in our 30s and 40s, the surprising connection between metabolic health and the brain, and how our everyday choices may influence whether our brain's immune cells protect us or work against us. We also get into the role of ultra-processed foods, blood sugar and insulin, the gut microbiome, environmental toxins, sleep, inflammation, mitochondria, vitamin D, and some of the biomarkers Dr. Perlmutter believes are worth knowing. And for women, we explore what happens to the brain during menopause, the latest conversation around estrogen and hormone replacement therapy, and why women face a greater risk of Alzheimer's.   Dr. Perlmutter also shares fascinating new research that could change how we think about Alzheimer's, Parkinson's, MS, traumatic brain injury, and other neurological conditions — including why the future of brain health may look very different from the traditional “wait for symptoms, then treat” approach. This episode left me feeling incredibly hopeful about how much influence we may actually have over the future of our brains. If you've ever worried about your memory, your family history, or simply want to stay sharp and resilient as you age, this is a conversation you don't want to miss. Key Moments You'll Love ✨ :

Doing more does not scale your business. It stalls it. Diluted focus gets you diluted results, and the owners who grow fastest are usually the ones doing fewer things, not more. In this episode of Service Business Mastery, Tersh Blissett and Josh Crouch sit down with Josh Zolin, CEO of Windy City Equipment Service and author of Blue is the New White, on how one simple shift, a single company wide focus every 90 days, took the guesswork out of hitting his goals. Josh breaks down how he points his entire company, from himself to the parts runner, at one goal each quarter, why focusing on less feels scarier than it should, how your role as the owner keeps changing as you scale, and the leadership habit that quietly runs off your best technicians. If you run a home service business and you are busy all day but not moving the way you want, this conversation is the reset. This episode is brought to you in partnership with Upfrog, one of our show partners. Upfrog turns paid ad spend into booked, sold system replacements instead of wasted leads. Learn more at upfrog.com. CHAPTERS 0:00 – Why Diluted Focus Gets You Diluted Results 2:31 – Meet Josh Zolin: Blue is the New White and Windy City 8:15 – The Identity Shift Every Owner Faces as They Scale 11:49 – The Unteachable Lessons You Have to Learn Yourself 14:40 – Why More Information Is Making Us Learn Slower 17:23 – AI as the Trades' Best Recruiter 20:25 – Navigating Private Equity as a Small Operator 27:12 – The 90 Day Single Focus System That Hits Goals Every Time 29:10 – Focusing on One Thing Without Letting the Rest Fall Apart 32:19 – The In-N-Out Lesson: Do Fewer Things, Better 35:26 – Why Focusing on Less Feels Scary, and How to Lead Through It 38:25 – Four Big Things a Year: Segmenting Focus Across Profit Centers 40:32 – Parkinson's Law: Use Time as a Tool 44:00 – Why 80% Done by Someone Else Is 100% Awesome 46:00 – The Perfectionist Tech Trap and Unspoken Expectations 49:40 – Where to Find Josh: Book, Podcast, and Academy WHAT YOU'LL LEARN - The one shift that lets you hit your quarterly goals every time: a single company wide focus every 90 days - Why doing less feels scarier than doing more, and how to lead your team through it - How your job as the owner keeps changing as you scale, and how to stay valuable - Why more information can make you and your team learn slower, not faster - How small operators actually beat private equity, and why it comes down to culture - The leadership habit that quietly runs off your best technicians - Why 80% done by someone else is 100% awesome, and how perfectionism keeps you small THIS EPISODE IS BROUGHT TO YOU BY UPFROG System replacement leads from paid ads, nurtured and booked into sold jobs before your team arrives: upfrog.com MARKETSTORM An AI-powered advertising platform. Results vary by market, budget, and campaign configuration: https://marketstorm.ai/ CALLRAIL CallRail's Voice Assist is a 24/7 AI voice assistant that answers every call, handles customer questions, and books jobs directly onto your calendar, all without you ever having to step away from the current job. Try Voice Assist for free today at voiceassist.com BREEZY Capture 25-30% more clients with Breezy AI Agents. Use code 'SBM' to book a demo and get $500 on us: https://bit.ly/4ihjXkx PHONETAP Your calls hold the key to growing your business. PhoneTAP gives you instant AI analysis, real customer lifetime value, and tools to coach your team. Learn more: phonetap.ai/demo COMPANYCAM Capture work, track job progress, and stay connected from the field to the office with photo documentation and AI tools that keep work moving. Start a free trial at https://companycam.com/ CONNECT WITH OUR HOSTS AND GUEST Tersh Blissett: https://www.linkedin.com/in/tershblissett/ Josh Crouch: https://www.linkedin.com/in/josh-crouch/ Josh Zolin, Windy City Equipment Service: https://www.linkedin.com/in/joshzolin/ https://joshzolin.com (his book, podcast, and academy are all there) ABOUT SERVICE BUSINESS MASTERY Service Business Mastery helps home service owners run better, more profitable companies. Every week, Tersh Blissett and Josh Crouch break down the operations, technology, and leadership behind growing an HVAC, plumbing, or electrical business, with the operators actually doing the work. More at https://servicebusinessmastery.com/ Want the frameworks from each episode in your inbox? Join the free Service Business Mastery newsletter: [ADD: SBM newsletter link] Subscribe on YouTube and follow us on Spotify and Apple Podcasts so you never miss an episode. If this one helped, share it with an owner who needs it. #ServiceBusinessMastery #HomeServices #Leadership #BusinessScaling #Trades

What if the health of your brain decades from now is being shaped by what you are doing today? We tend to think about Alzheimer's and cognitive decline as problems that show up later in life, once memory starts slipping or confusion becomes noticeable. But many of the factors associated with brain decline can begin much earlier. Blood sugar, insulin resistance, sleep, inflammation, muscle mass, exercise, social connection, oral health, and even the medications you regularly take may all influence the environment your brain is aging in. This matters because brain health gives you more areas to act on than most people realize. You can pay attention to metabolic markers before they become major problems, build and preserve muscle, protect your sleep, stay socially connected, take care of your oral microbiome, and understand which emerging therapies actually have evidence behind them. The earlier you start thinking about your brain this way, the more opportunity you have to influence how well it functions later. Dr. David Perlmutter is a board-certified neurologist, six-time New York Times bestselling author, and internationally recognized expert in brain health, nutrition, and neurodegenerative disease. His latest book, Brain Defenders, explores microglia, the brain's immune cells, and how their function may influence conditions including Alzheimer's and Parkinson's. His work focuses on giving people practical ways to protect brain health through metabolism, lifestyle, and emerging neuroscience. What's Discussed: (05:51) What research suggests about slowing or even improving cognitive decline in people already diagnosed with Alzheimer's through intensive lifestyle intervention. (10:47) Why Alzheimer's should not be viewed as purely genetic and how lifestyle and metabolic health can influence risk even when genetic predispositions are present. (12:19) How loneliness and social isolation may affect brain health through stress, cortisol, oxytocin, inflammation, and changes in the brain's immune cells. (20:50) Why the biological conditions associated with cognitive decline may begin in your 40s and 50s, decades before memory problems become obvious. (30:34) How exercise supports the brain through BDNF, irisin, and other chemicals released during muscle activity, and why both cardio and strength training matter. (38:00) Why restorative sleep is an active period for memory consolidation and brain recovery, and how fragmented sleep can undermine brain health even when you spend eight hours in bed. (1:04:34) What the science currently says about NAD, NR, NMN, and IV NAD for mitochondrial function, biological aging, and cognitive health. (1:12:04) How periodontal disease, the oral microbiome, and frequent use of certain antibacterial mouthwashes may affect nitric oxide, metabolism, and long-term brain health. (1:23:05) What emerging research says about GLP-1 drugs for Parkinson's and Alzheimer's, and why using or microdosing them specifically for brain protection is still ahead of the evidence. (1:33:25) Why homocysteine and fasting insulin are two blood markers worth paying attention to when assessing metabolic and long-term brain health.   Thank You to Our Sponsors! Magic Mind: Head over to magicmind.com/jen and use code JEN at checkout. Momentous: Ready to try supplements that actually do what they claim? Head to livemomentous.com and use code JEN for 35% off your first subscription.  Therasage: Visit therasage.com and use code JEN to get 15% off your order. Your skin Prolon: Prolon is offering listeners 30% off sitewide plus a $40 bonus gift when you subscribe to their 5-Day Program! Just visit prolonlife.com/JENNIFERCOHEN and use code JENNIFERCOHEN to claim your discount and your bonus gift. Tru Niagen®: For supplements that are rigorously tested, third-party verified, and actually deliver what's on the label, head to truniagen.com Find more from Jen Cohen: Website: jennifercohen.com Instagram: @therealjencohen Books: jennifercohen.com/books Speaking: jennifercohen.com/speaking-engagements   Find more from Dr. David Perlmutter: Website: drperlmutter.com Instagram: @davidperlmutter Facebook: David Perlmutter M.D.  YouTube: @davidperlmutterMD LinkedIn: David Perlmutte, MD Book: Brain Defenders  

Colby Parkinson, tight end for the Los Angeles Rams, joins Jonny Ardavanis for a raw conversation about faith, football, and what it really means to be "salt and light" (Matthew 5:13-16) in a secular, high-pressure NFL environment.Colby opens up about a difficult season where he feared being cut from the roster, the identity crisis that followed, and how a shift from a works-based mindset to a grace-based one transformed not just his walk with Christ — but his career, leading to a breakout season with the Rams.Stay accountable in a digital world: check out Accountable2You at accountable2you.com/dialin — use code DIALIN for 25% off your first year.In this episode, Colby and Jonny dig into:- What it looks like to honor God through work ethic and integrity in professional sports- How to handle failure, benching, and uncertainty as a believer- The temptations of wealth, fame, and access that come with NFL life- Being a godly husband and father to Melanie, Brooks, and Forest Parkinson- Why character (salt) isn't enough without vocal witness (light)- How to have gospel conversations without fear of "ruffling feathers"Whether you're an athlete, entrepreneur, or working a 9-5, this conversation on purpose, humility, and living for an audience of One will challenge and encourage you.Timestamps / Topics: Matthew 5:13-16 | Salt & Light | NFL Faith | Identity in Christ | Overcoming Setbacks | Christian Fatherhood | Workplace Ministry

This week, Dr. Kahn returns to one of his passion topics: educating young people about healthy lifestyles beginning in middle school and high school, if not earlier, and setting them up for a healthy future. A new study finds that the risk of heart disease and actual changes in the arteries are both common by age 23. It's a tragic reality. Other topics include dry cleaning and Parkinson's disease, amino acids and prostate cancer risk, meal timing and longevity, cooking classes and healthy diets (PlantRN), statins at age 80, exercise and the reversal of artery disease, lipoprotein(a) and heart disease, and alcohol versus healthy lifestyles in relation to the risk of sudden cardiac death.  Thanks to WellBean for sponsoring this episode. Use the discount code DrKahn15 on delicious and healthy food bars made with legumes. They're my favorite snack.

Dr. Greg Eckel is neurogeneration pioneer who helps people suffering from Parkinson's Disease reclaim and revitalize their lives.  His latest book, "Defying Parkinson's," provides detail on cutting-edge therapies that outperform standard neurological treatments. Learn more at https://brainregen.com Purchase peptides at https://biolongevitylabs.com Promo Code HABER for 15% off 

Dr. Masud Husain is a Professor of Neurology & Cognitive Neuroscience at the University of Oxford and a leading expert on the science of motivation, apathy, and neurological diseases. We discuss how dopamine and specific brain circuits shape motivation, including how the brain weighs the trade-off between effort vs reward when deciding what goals to pursue. Dr. Husain also explains practical tools to increase motivation, reduce distractions, and make it easier to start and maintain goal pursuit. We also discuss dementia, Parkinson's and Alzheimer's disease, including new insights into cognitive resilience and factors that help protect against age-related cognitive decline. Show notes: https://go.hubermanlab.com/masud-husain-295 Thank you to our sponsors AG1: https://drinkag1.com/huberman David: https://davidprotein.com/huberman BetterHelp: https://betterhelp.com/huberman Eight Sleep: https://eightsleep.com/huberman Function: https://functionhealth.com/huberman Timestamps (00:00:00) Masud Husain (00:02:24) Apathy, Motivation (00:08:07) Rewards, Apathy & Motivation; Dopamine (00:13:20) Sponsors: David & BetterHelp (00:15:44) Types of Apathy; Goal Prioritization: Effort vs Rewards (00:23:26) Motivation, Apathy, Tool: Activation Energy & Overthinking (00:29:24) Tools to Increase Motivation: Incentives, Subdivide Tasks, Planning (00:35:13) Subjective Effort, Mental Framing; Learning & Motivation (00:42:24) Sponsors: AG1 & Eight Sleep (00:44:54) Perseverance, Failure; Finding Your Passion, Depression vs Apathy (00:50:58) Self-Concept, Ambition; Life Satisfaction (00:58:25) Psychedelics, Anhedonia & Changing Self (01:03:09) Personal & Social Identity, Tools: Curiosity, Purpose & Dementia Risk (01:11:58) Addiction, Dopamine; Social Media & Dopamine "Hits"? (01:18:36) Sponsor: Function (01:20:13) Dopamine, Parkinson's Disease; Other Roles of Dopamine (01:26:59) Life Purpose, Culture; Reflection, Weighing Decisions (01:34:21) Internal & External Attention (01:39:59) Internal Chatter, Distraction; Working Memory, Stimulants, Nicotine (01:48:54) ADHD, Diagnosis; Attention & Motivation (01:54:34) Goal Planning & Perseverance (01:59:44) Alzheimer's Disease, Dementia, Apathy, Tools: Dementia Risk Factors (02:06:55) Neurodegenerative Disease & Emerging Treatments (02:10:59) Can You Train Attention?, Tool: Reduce Distraction (02:15:14) Enrichment, Art (02:17:45) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

Broadcast from KSQD, Santa Cruz on 8-20-2026: An emailer asks about amlexanox for mast cell activation syndrome (MCAS). Dr. Dawn first walks through MCAS diagnostic criteria—requiring symptoms across at least two of four categories (skin, low blood pressure, abdominal, respiratory), with serum tryptase testing performed both during and after a flare. She grades amlexanox as a C: originally FDA-approved only as a topical paste for canker sores, later approved in Japan as an asthma treatment, but never validated for MCAS and pushed largely by a single compounding pharmacy and its influencer clones. She recommends conventional agents first—antihistamines, montelukast, cromolyn, quercetin, aspirin for flushing, and Xolair anti-IgE antibodies for severe cases—plus microcrystalline cellulose as the safest capsule filler if compounding of amellanox is pursued. Most ovarian cancers—including nearly all fatal cases—actually originate in the fimbriae of the fallopian tubes rather than the ovaries themselves. Opportunistic salpingectomy tacks a five-minute fallopian tube removal onto any abdominal surgery (tubal ligation, hernia repair, gallbladder, appendectomy), potentially reducing lifetime ovarian cancer risk by 65% -80% based on epidemiological data from Swedish, Canadian, and Danish registry studies. Dr. Dawn recommends particular consideration for non-childbearing women with BRCA1/2 or family history of breast or ovarian cancer. Deep brain stimulator devices manufactured after 2020 (about 40,000 U.S. patients) contain adaptive-DBS capability that can be activated via firmware upgrade without additional surgery. Rather than delivering constant stimulation like older devices, adaptive DBS reads beta oscillations (13-30 Hz motor-control brainwaves) in the basal ganglia and modulates output in real time—reducing stimulation as L-DOPA peaks from drugs and increasing it as medication wears off, smoothing the swings between agitation and freezing. Sleep improvement has emerged as a notable secondary benefit, potentially slowing disease progression. The technology is also being investigated for dystonia, essential tremor, OCD, and Tourette's syndrome. Chinese company StarMed is developing brain-computer interfaces closely resembling Neuralink designs, benefiting from aggressive government funding, large patient populations, and reduced tort liability. One trial uses an eight-probe device placed atop the dura mater (avoiding brain penetration) connected to a pneumatic glove that has restored eating and drinking function in about twenty paralyzed patients over twenty months. A more invasive Shanghai trial implanted 256 probes on the neural cortex of a woman with epilepsy who could operate social media and control a wheelchair within two weeks; a related U.S. system using 65 hair-thin sensors enabled speech with just ten-millisecond delay. An emailer describes recurring two-week viral illnesses (sore throat, swollen glands, congestion, cough, body aches) recurring every 4-6 weeks. Dr. Dawn frames the question as either impaired immunity or changed exposure. She recommends starting with a CBC to rule out blood dyscrasias like leukemia, checking urine mycotoxins for mold exposure, then examining behavioral changes—new job, handling cash before eating, and the well-documented protective effect of masking in public that dramatically reduced cold rates during COVID. Dr. Dawn covers three health policy items. The good: new USDA dietary guidelines flip the food pyramid, putting protein, dairy, healthy fats, vegetables, and fruits at the top, with whole grains reduced to a small band, and it's recommendation 1.2 g/kg protein daily. The bad: an executive order attempting to reduce childhood vaccines from 18 to 11 and separate MMR into individual components—impossible since no U.S. manufacturer makes the individual antigens, and misguided since infant hepatitis B vaccination prevents mother-to-child liver cancer transmission. The ugly: a 26-year-old heart transplant recipient whose insurer initially dropped coverage of her generic anti-rejection drug, then "ghost approved" it at $1,000 for 90 days versus the previous $180. Mark Cuban's Cost Plus Pharmacy now supplies her the same medication for $300 (cost plus 15% profit plus 5% handling), highlighting the massive markups embedded in the standard pharmacy chain. For a time before that, the mother of the heart donor stepped up and paid for the recipients anti-rejection drugs to keep her son's heart beating.

Send us Fan MailGet your notes app or a fresh piece of paper ready, because this conversation with former movie executive and tech entrepreneur Steven Puri took a turn into pure gold. We went so deep into the mechanics of productivity that we completely lost track of time—proving the exact focus concepts we were discussing! If you've ever felt like modern digital distractions are stealing your workday before you even get started, this episode is your ultimate antidote.In this episode, Steven and I dive into the neuroscience of focus, master-level time-boxing, and actionable dopamine management for nurse solopreneurs. We break down why getting into a flow state isn't just about willpower, but about building the right environment, audio cues, and routines to let your creative brain excel. Tune in to discover how you can transform a single hour of daily focus into monumental progress for your health writing business.About Steven PuriSteven is the Founder and CEO of The Sukha Company with the mission to help millions of people find their focus, achieve more and have a healthy work life.Steven's career started as a newscaster/interviewer for the #1 youth news show in the DC/Baltimore market (on WTTG-TV) and then as a junior software engineer & Thomas J. Watson Scholar at IBM. After attending USC in Los Angeles, he began working in film production and produced computer-generated visual effects for 14 movies including Independence Day which won the Academy Award for Visual Effects.Steven's first tech company was Centropolis Effects that produced those CGI effects, and he eventually sold it to the German media conglomerate Das Werk when he was 28.Steven then produced some indie films and eventually went studio-side to develop and produce live-action features as a VP of Development & Production at 20th Century Fox (running the Die Hard and Wolverine franchises) and an EVP at DreamWorks Pictures for Kurtzman-Orci Productions (Star Trek 11, Transformers 1&2, Eagle Eye, Transformers: Prime, et al.).After Fox, Steven returned to building tech companies and had two failed start-ups before founding The Sukha Company – ‘sukha' means ‘happiness from self-fulfillment' in Sanskrit. The Sukha is a focus app that bundles all the tools necessary to enter into a Flow State and a have healthy, productive workday.Steven now lives in Austin, TX.Dopamine Management and Time-Boxing for Nurse WritersToday on the Savvy Scribe Podcast:Why modern tech platforms are intentionally engineered to steal your attention—and how to reclaim your life through effective dopamine managementWhat actually happens in your brain during a flow state, including fascinating neuroimaging findings from FMRI scans.How to conquer the “cold start problem” in the morning and stop reaching for quick digital hits when your work gets frustrating.Unforgettable stories from blockbuster Hollywood screenwriters on using physical environments and personal chronotypes as focus triggers.How a busy high school vice principal and dad used just one focused hour a night to complete his PhD dissertation.The brain science behind why your best ideas strike while doing laundry, walking, or taking a shower.How to harness time-boxing and Parkinson's Law to get more done in two hours than you used to get done all day.The surprising power of ambient audio triggers, from 60–90 BPM focus tracks to real Himalayan rain and Viennese coffee shop sounds.Steven's simple 30-day challenge that will completely transform your daily momentum before you even check your phone in the morning.Mentioned Resources:Sukha (Flow State AppFlow: The Psychology of Optimal Experience by Mihaly CsikszentmihalyiThe Net and the Butterfly: How to Unlock Your Inner Genius by Olivia Fox Cabane and Judah PollackWelcome to the Savvy Scribe Podcast, I'm so glad you're here! Before we start the show, if you're interested, we have a free Facebook group called "Savvy Nurse Writer Community"I appreciate you following me and listening today. I would LOVE for you to subscribe: ITUNESAnd if you love it, can I ask for a

Former Giants Pro Bowler Leonard Marshall joins Joe Rose to discuss the impact of CTE and brain health in football, including the movie Concussion and how it portrayed one of his former teammates. Marshall is promoting brain health training through Focus Brain Therapy and discusses efforts to help former football players dealing with conditions such as ALS and Parkinson's. He also reflects on playing alongside Lawrence Taylor, the Giants' tradition of dominant defenses, Bill Parcells' coaching style and his own journey back to school after football. Plus, Marshall looks back on winning two Super Bowls with the Giants.

The Savior set the perfect example in doing the Father’s will. We strive to do His will as we move forward in faith on our personal journeys. Click here to view the speech page. See omnystudio.com/listener for privacy information.

In this episode of The Story Engine Podcast, I sit down with brain health and dementia expert Eric Collett to explore a question I think a lot of us would rather avoid: What if the problems we experience in our brain, energy, focus, and mental health today are warning signs of something deeper? Eric explains why conditions like Alzheimer's and Parkinson's can begin developing decades before obvious symptoms appear, and why things like brain fog, low energy, declining productivity, gut health issues, and memory changes deserve more attention than we often give them. We also unpack Eric's powerful "hardware vs. software" analogy: sometimes we keep trying to learn more, work harder, or become more productive when the real problem is that our underlying biology needs attention. What makes this conversation especially powerful is Eric's personal story. After 16 years working in assisted living and memory care, he reached a breaking point when he had to leave his family's evening plans to return to work with a dying resident. That night, he looked in the mirror and realized he was overweight, exhausted, brain foggy, chronically stressed, and ignoring the warning lights in his own life. Within days, he decided to leave his career and build what became A Mind for All Seasons. We talk about his four-part process—measure, learn, apply, and adjust—and why information alone isn't enough to change your health. Ultimately, this episode is about taking care of your brain before you desperately need to, recognizing that common doesn't always mean normal, and taking the next right step toward having the energy, clarity, and capacity to live the life you actually want.

Quantum Scientist Patrick Coles Reveals How Tumors Protect Your Mitochondria From Toxic Overload Cancer might not be the enemy your doctor says it is. What if tumors are actually your body's emergency detox system, built on purpose to protect you from something far more dangerous? Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Patrick Coles, Ph.D., Chief Scientist at Normal Computing, where he develops novel computing hardware for AI applications. Previously a Staff Scientist at Los Alamos National Lab, Coles led their near-term quantum computing group and made significant contributions to quantum computing theory. He holds a Ph.D. in Chemical Engineering from UC Berkeley and a Master of Philosophy in Biochemistry from Cambridge, and he's currently developing a new theory for cancer and chronic disease, the subject of this conversation. His rare combination of hard physics and deep biochemistry gives him a radically different lens on one of medicine's most misunderstood diseases. Coles lays out his Toxin Sequestration Theory, a framework that reframes cancer tumors not as malignant accidents but as intentional storage vaults the body builds to sequester toxins, heavy metals, seed oils, mold, and excess glucose, away from healthy tissue and mitochondria. He and Dave connect the dots between this theory and chronic disease, biohacking fundamentals, and why chemotherapy itself behaves as a toxin that can backfire. They dig into oxalates, deuterium, linoleic acid, circadian biology, and the detox protocols that support the body's natural ability to shrink these toxic reservoirs. This conversation challenges the mainstream genetic theory of cancer, explores the metabolic theory popularized by Thomas Seyfried, and lands on a radical, functional medicine-aligned framework for anyone serious about longevity, anti-aging, and human performance. Dave and Coles also break down how sleep optimization, fasting, ketosis, and a carnivore approach to nutrition support the body's detox hierarchy, from fat tissue and the liver to moles, cysts, and eventually tumors themselves. This is essential listening for anyone serious about biohacking, functional medicine, mitochondria health, brain optimization, nootropics, and taking full control of their metabolism and longevity. You'll Learn: Why toxins may be the root cause of Alzheimer's, Parkinson's, autism, and most chronic disease How Toxin Sequestration Theory reinterprets tumors as the body's backup detox organs Why chemotherapy ranks among the most tissue-damaging toxins, and what happens when a tumor bursts The role of oxalates, deuterium, heavy metals, and seed oils in cancer cell hoarding Why moles, cysts, lipomas, and nodules may be minor versions of the same detox response How circadian rhythm, sleep, and light exposure affect the body's toxin excretion cycles What spontaneous tumor regression reveals about lowering your toxic burden Why tracking tumor progression matters no matter which treatment path you choose Thank you to our sponsors! - Download Dave's Free Peptide Guide at daveasprey.com/peptide-guide. - ZenBud | Dave's Nervous System Biohack. Visit zenbud.health and use code DAVE15 at checkout for a discount. - Timeline | Visit timeline.com/dave to learn more about Mitopure and get 20% off your first order for a limited time. - Just Thrive | Get a free 90-day supply of Digestive Bitters (a $90 value) when you start a 90-day Just Thrive Probiotic subscription at https://get.justthrivehealth.com/pages/asprey Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: toxin sequestration theory, cancer theory, Patrick Coles, quantum computing scientist, thermodynamic computing, Normal Computing, Los Alamos National Lab, chemotherapy toxicity, oxalates cancer, deuterium toxin, Stephanie Seneff, heavy metal detox, mycotoxins tumors, seed oils cancer, linoleic acid, oleic acid oxidation, lipid peroxidation, glucose toxicity, mitochondria downregulation, genetic theory of cancer, metabolic theory of cancer, Thomas Seyfried, spontaneous tumor regression, backup detox organ, circadian rhythm cancer, mold toxins, forever chemicals, microplastics, bile flow, activated charcoal binders, cholestyramine Resources: • Follow Patrick's Work At: https://www.instagram.com/patrickc_tst/ • Watch Gabby's Podcast At: https://www.youtube.com/@GabbyReece • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15? • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 00:58 – Introducing Patrick Coles 04:08 – Toxin Sequestration Theory 06:26 – Defining a Toxin 14:13 – Cancer as Backup Detox Organ 15:01 – History of the Theory 16:30 – Deuterium and Oxalates 21:31 – Cancer Theories Compared 28:06 – Chemotherapy and Toxic Overload 37:23 – Tiered Toxin Storage System 45:17 – Diet, Light, and Circadian Rhythm 50:39 – Detox Protocols and Binders See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

AhmanGreen30 on going public with his fight against early-onset Parkinson's, football's role in causing the disease & also aiding his treatment, his first impressions of GB, what game day in Lincoln was like, why this is a pivotal season for Matt LaFleur and more. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Learn more about Parkinson's and find support: https://dpf.org  Intimacy, in all its forms, doesn't disappear with a Parkinson's diagnosis, but it does change. In this episode, Dr. Kelly Rees joins Chris Krueger for a candid conversation about staying close when Parkinson's changes your body, your self-image, and your relationship. They talk through what to do when touch becomes unpleasant, how to navigate mismatched desire without pressuring each other, impulse control changes related to dopamine agonists, and how couples stay connected when symptoms mean sleeping in separate beds. Whether you live with Parkinson's or care for someone who does, Dr. Rees's closing advice holds the whole conversation: don't give up on yourself. Kelly Rees, PhD is a board-certified therapist who specializes in intimacy, relationships, and sexual wellbeing in the context of Parkinson's. Dr. Rees has 15 years of clinical experience working with adults and couples, and she co-developed a program offering free intimacy and relationship classes to the Parkinson's community. Her work focuses on how Parkinson's symptoms, medications, body changes, and shifting roles can affect desire, connection, and communication, and on helping individuals and care partners adapt in ways that support quality of life and emotional closeness. This conversation comes from the Davis Phinney Foundation's June 2026 Live Well Today webinar. Watch the full webinar video here: https://youtu.be/G6c7SQnHrLs Sign up for updates on webinars, events, and resources for the Parkinson's community: https://dpf.org/newsletter

Keith Murphy & Andy Fales break down the Little League sign-stealing controversy involving Davenport Northwest, which advanced to the Little League World Series despite an Iowa player being accused of relaying signs from second base. They discuss the difference between Little League and Major League Baseball rules, whether the incident was simply gamesmanship or crossed the line, and whether coaches should be held responsible. They also cover ESPN's Pat McAfee saturation, Stephen A. Smith, the changing sports-media landscape, Penn State's alleged fraternity cocaine-trafficking case, Iowa State football's unprecedented roster turnover, the Iowa State Fair, Jason Parkin's Parkinson's diagnosis, Columbia House shutting down, the most annoying movie coworkers with Mr. Movie, new movie recommendations, and MORE! Murph & Andy. Sports and MORE! Only on Iowa Everywhere. Learn more about your ad choices. Visit megaphone.fm/adchoices

Episode 26-33 Is Insulin Resistance The Greatest Threat To Your Health? Nearly EVERY chronic disease is strongly linked to Insulin Resistance. Or, stated another way… As you age, Insulin Resistance may be THE factor that causes you to suffer with one or more of the following conditions: High Blood Pressure, Diabetes, Alzheimer's, Stroke, Parkinson's, Fibromyalgia, Multiple Sclerosis, Obesity, Heart Disease, Autoimmune Disorders, Vision Problems, Kidney Failure, Neuropathy, Bipolar Disorder, Depression.  On this episode I address the basics regarding Insulin Resistance. Specifically I ask 5 questions that you need to know the answers to should you desire to live a long and HEALTHY life:   1) What is Insulin Resistance? 2) Why is it so harmful? 3) What causes it? 4) How can it be corrected? 5) How do you know if you have it?   Give this episode a good listen if you want to prevent, and possibly reverse, Insulin Resistance and the negative health consequences that come with it. And, as always, be sure to share this episode with a friend.  Thanks!  ———————- Want to learn more? Continue the conversation regarding this episode, and all future episodes, by signing up for our daily emails. Simply visit: GetHealthyAlabama.com  Once there, download the "Symptom Survey" and you will automatically added to our email list. ———————- Also, if you haven't already, we'd appreciate it if you'd subscribe to the podcast, leave a comment and give us a rating. (Thanks!!!)  

               * This podcast is for informational and educational purposes only. It is not intended to diagnose or treat any disease. Please consult with your health care provider before making any health-related changes.

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Big Pharma bet billions on one theory: clear the amyloid, cure Alzheimer's.A new Cochrane review of 20,000+ patients just proved them wrong — these drugs don't work, and they may be putting your brain at risk. So what's really driving this epidemic?My guest today, six-time New York Times bestselling author and board-certified neurologist Dr. David Perlmutter, says the answer lies in a set of cells most people have never even heard of — and he lays it all out in his new book, Brain Defenders.The good news is, you already have more control over them than any drug could ever give you.We're talking about microglia, the brain's immune cells, and why the choices you make today may matter more than anything a prescription pad can offer.For full show notes and transcript: https://drgundry.com/david-perlmutter-alzheimersOn this episode, you'll learn: All about the new study that found leading Alzheimer's drugs deliver almost no benefit (02:09)Why the so-called enemy in your brain is not what we thought at all (07:34)What microglia are, and why these overlooked immune cells may be the real gatekeepers of your brain's health (05:15)How everyday metabolic issues like blood sugar and insulin resistance can affect your brain (09:30)Why one in nine Americans over 65 is already living with dementia (and most don't know it) (14:08)The surprising connection between Parkinson's, depression, and even autism spectrum conditions (15:11)How THIS lifestyle program helped 70% of Alzheimer's patients stabilize or even improve their cognitive function — no drugs required (17:09)The one mindset shift Dr. Perlmutter says has to happen before any diet or exercise plan will actually work for your brain (22:17)Why getting quality sleep does more for your brain than you think (27:49)The simple blood test you should request NOW to gauge your Alzheimer's risk (33:25)Why women make up two-thirds of Alzheimer's patients (35:29)The critical window for starting hormone replacement therapy (40:08)The truth about antibacterial mouthwash, and why it might be quietly working against your brain health (58:14)A 25-year-old flossing study that predicted exactly what today's top neurology journals are just now confirming (01:00:05)Dr. Perlmutter's honest answer to whether you should take the newer Alzheimer's drugs your doctor may be recommending (01:05:31)More about Dr. David Perlmutter:Dr. David Perlmutter's websiteDr. David Perlmutter's InstagramNew book: Brain Defenders: Harness the Power of Your Immune Cells to Protect Your Brain for Life by Dr. David PerlmutterResearch:Cochrane ReviewTanzi StudyThank you to our sponsors! Check them out: Transform your sleep experience with Cozy Earth bedding. Go to cozyearth.com/gundry for 20% off. Go to thrivemarket.com/GUNDRYPODCAST for 30% off your first order, plus a FREE $60 gift.Go to Quince.com/gundry to upgrade your wardrobe and get free shipping on your orderGet a quote today at Progressive.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The sign of a true grinder: The Art of Putting and The Art of the Short Game are on their shelf. Stan Utley wrote them, and they turned a PGA Tour winner into one of the most sought-after coaches in the world. Now the Director of Instruction at Shady Oaks Country Club, Utley has helped shape the swings of Darren Clarke, Sergio Garcia, Joaquin Niemann, Jay Haas and countless others. On this episode, Utley joins host Tom Coyne at Shady Oaks, surrounded by Ben Hogan's clubs and trophies, to tell stories from his illustrious career, explain why your job is never to make the putt, and share how he's battling a Parkinson's diagnosis with faith and a refusal to give in. It's an episode full of wisdom from one of the sharpest minds in coaching. The Golfer's Journal and this podcast are made possible by reader support. If you enjoyed this episode, please consider becoming a member here: https://glfrsj.nl/MembershipsYTThe Golfer's Journal Podcast is presented by Titleist.

Relying only on low-impact exercise can leave you more fragile as you age, because your bones and connective tissue need impact to stay strong. Graham Tuttle, a coach, the author of Born to Sprint, and the self-styled Barefoot Sprinter, argues that sprinting, jumping, and throwing are the real markers of a healthy body at any age, and that stripping impact out of your training in the name of safety quietly erodes the very capacity it is meant to protect. In this conversation, Graham and Coach Allan get into why impact signals your bones and your brain that they are still needed, how training barefoot restores feedback and movement most of us have lost, the story of Graham coaching his own father to run again 15 years into a Parkinson's diagnosis, and his 10% rule for reintroducing impact safely when you are starting from badly out of shape. Time Stamps: 06:00 Trusting the body's natural design 07:44 Poor eyesight, lifting for looks, and losing body connection 12:27 Rethinking the reductionist physical-therapy model 13:42 Fascia, movement patterns, and the whole body 17:57 Why impact keeps the body and brain online 20:51 How the muscle system manages force 24:04 Physical limitation and how you perceive the world 30:23 Impact, hormones, bones, and the brain 32:56 His father's Parkinson's and rethinking fitness 35:55 Finding purpose and meaning in older age 39:44 Jeffy: starting from ground zero 41:12 The philosophy of sprinting 46:44 Using impact to shake things loose 48:25 Rebuilding movement patterns from the ground up 54:03 Sprinter swinging and plyometrics 55:01 Restoring the ability to sprint Links: Graham Tuttle's book, Born to Sprint: Unlock Your Natural Strength, Speed, and Athleticism: https://amzn.to/4xzlCqa Graham's website: https://thebarefootsprinter.com/ Graham on YouTube, Facebook, LinkedIn, TikTok, and Instagram: The Barefoot Sprinter Coach Allan's book, The Wellness Roadmap: https://amzn.to/3U1xEdn  

Midwest lawmakers have tried and failed to ban paraquat, a toxic weedkiller that's been tied to Parkinson's disease. One state senator plans to keep fighting. Plus: The federal government has released new rules controlling how farmers can use the controversial herbicide dicamba.

Alzheimer's disease has increased 134% since the year 2000. Over 7 million Americans are currently living with full-blown Alzheimer's disease. Not mild cognitive impairment, not brain fog, but diagnosed Alzheimer's. One in five women and one in ten men will receive that diagnosis in their lifetime. And according to ALZ.org, the risk has gone up 134% in just 24 years. For many people, this is not a genetic crisis: it's a lifestyle crisis, and that means it is largely preventable. In this episode, Dr. Chris Motley sits down with integrative nurse practitioner, author and Alzheimer's prevention advocate Dani Williamson — whose mother died of Alzheimer's at 78 with zero genetic markers for the disease — to have the honest, urgent conversation about what is actually driving the dementia epidemic, and what every person can do right now to protect their brain. In this episode you'll discover: Why Alzheimer's has increased 134% since 2000 while heart disease has decreased — and what that statistical reversal tells us about the true nature of this disease Why one in five women will be diagnosed with Alzheimer's — more than breast cancer and prostate cancer combined — and why it remains dramatically underfunded and under-discussed The shocking genetic test result that changed how Dani understands her mother's disease — and why most Alzheimer's cases are lifestyle-driven, not genetically determined How childhood trauma, smoking, alcohol, poor sleep, chronic stress, and mold exposure combined to create the perfect conditions for Alzheimer's in Dani's mother's brain The mold-Alzheimer's connection: how mycotoxins change the morphology of nerve cells, create biofilm in the brain, and produce the "snot in your brain" effect driving cognitive decline How hidden viruses — including HSV-1 (cold sores), Epstein-Barr virus, and HHV-6 (Roseola) — increase Alzheimer's risk by damaging nerve cells and disrupting brain signalling Why one in six people carry the herpes simplex virus without knowing it — and how managing it proactively could reduce dementia risk The thyroid-brain connection: how Hashimoto's thyroiditis and thyroid dysfunction directly drive brain fog, memory loss and early cognitive decline Why perimenopause and menopause are being misdiagnosed as early dementia — and how optimising estrogen, progesterone and testosterone can bring memory and clarity back The endometriosis-brain connection: how inflammation in the reproductive system blocks the conception vessel meridian's energy from reaching the brain and thyroid Why the tampons and pads most women have used for decades contain glyphosate and bleach — and how switching to organic products reduced period symptoms dramatically within the first two cycles How mold on corn, wheat and processed grains silently accumulates in the body — and why Dr. Motley's FDA contact confirmed that batches of corn are routinely rejected for dangerous mold levels Resolvins — the omega-3 derivative that goes beyond fish oil — and why Dani calls it one of the non-negotiables she will take until her final day Why low-dose naltrexone (LDN) may have an unexplored role in Alzheimer's prevention and inflammation control The TCM fire element connection: how the ovaries, adrenal glands and thyroid form an energetic circuit along the conception vessel — and why inflammation in the reproductive organs can starve the brain of qi Dani's six foundational steps for Alzheimer's prevention: eat well, sleep well, move well, poop well, de-stress well, commune well Why ballroom dancing is the number one exercise for memory — and why boxing is rapidly gaining ground for both Alzheimer's and Parkinson's prevention The Bristol Stool Chart explained: why daily bowel movements matter for brain health, what your stool shape reveals about toxin clearance, and why Dani says "poop like your poodle" The early warning signs of cognitive decline to watch for in aging parents — including increasing clutter, hoarding, and giving away money impulsively Why sleep is when the brain's glymphatic system flushes toxins — and how even one poor night of sleep impairs that critical detox process The role of lymphatic drainage, infrared sauna, and EAV testing in supporting brain health and reducing the toxic burden that accelerates cognitive decline Whether you have a family history of Alzheimer's, are noticing early signs in yourself or a loved one, or simply want to protect your brain for decades to come — this episode is key. Products and Testing Mentioned: Resolvins (SPM Ultra) — ask your integrative practitioner Low Dose Naltrexone (LDN) — prescription required; discuss with your doctor MicrogenDX genetic and bacterial testing DesBio Mold SSR Homeopathic Want more of The Ancient Health Podcast? Subscribe to the YouTube channel. ------  Follow Doctor Motley! Instagram TikTok Facebook Website Follow Dani Williamson https://www.instagram.com/daniwilliamsonwellness/ https://daniwilliamson.com/ Book: Wild and Well — available at daniwilliamson.com and major retailers Clinic: Williamson Wellness, Brentwood, Tennessee ------  *Most of us are mineral deficient and we don't even know it! Want to get your minerals in? BEAM Minerals is a simple shot of minerals each morning. Try BEAM Minerals at beamminerals.com/DRMOTLEY and use code DRMOTLEY for 20% off your first order. *Join Doctor Motley's newsletter for TCM insights and regular podcast updates https://www.doctormotley.com/ *Do you have a ton more in-depth questions for Doctor Motley? Check out his course on emotions and the body in his membership. You'll find other courses full of his expertise and clinical wisdom, plus bring all your questions to his weekly lives! To try risk-free for 15 days click here https://www.doctormotley.com/15

Dr. David Perlmutter — neurologist, New York Times bestselling author, and author of the new book Brain Defenders — joins Dr. Will Cole to reveal what he believes is the most important breakthrough in brain health science in decades: the microglial cell. He explains why the amyloid hypothesis that has dominated Alzheimer's research (and pharmaceutical spending) for 30 years has been definitively disproven by a Cochrane analysis, why a Harvard lifestyle study arrested Alzheimer's decline in 70% of patients without any drug, and what the April 2024 NEJM GLP-1 Parkinson's trial means for the future of neurodegenerative disease. They also cover the practical daily habits, foods, supplements, and lab tests that shift the brain's immune cells from destructive to protective — and why you are far more the architect of your brain's destiny than anyone has told you. For all links mentioned in this episode, visit http://www.drwillcole.com/podcastPlease note that this episode may contain paid endorsements and advertisements for products and services. Individuals on the show may have a direct or indirect financial interest in products or services referred to in this episode.Sponsors:Take the first step and learn at a pace that works for you. Visit WaldenU.edu.Give them meals + snacks that are actually right for where kids are developmentally - balanced, intentional and made to support real growth. Go to littlespoon.com/WILLCOLE and enter code WILLCOLE for 30% off your first order.Get a free 8-count Sample Pack of LMNT's most popular drink mix flavors with any purchase at drinklmnt.com/artofbeingwell. Find your favorite flavor, or share with a friendQUINCE.COM/WILLCOLE for free shipping and 365 day returns. Now available in Canada too! www.jshealthvitamins.com code WILLCOLE for 15% off at checkout LIFT Oléoactif® significantly reduced the primary wrinkle by more than 200%.† OR 200% reduction in wrinkles with LIFT Oléoactif®†* Disclaimer: *Clinical test: LIFT Oléoactif® in cream, results in 28 days, compared to placebo. LIFT Oléoactif® is a trademark of HALLSTAR FRANCE SAS. 95% see a reduction in eyebag volume* with Eyeseryl® Peptide Disclaimer: *Clinical test: EYESERYL® Peptide in cream, results in 28 days. EYESERYL® Peptide is a trademark of Lubrizol Advanced Materials, Inc. or its affiliates.Produced by Dear Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Join Me for the 90 Day Reset – https://buildyourbestfall.com/    You're eating clean, sleeping more, doing everything you're supposed to do for your health, and your body still isn't getting the message. In part 2 of this conversation, Harvard psychologist Dr. Ellen Langer explains why “chronic” doesn't mean permanent and shares a simple, science-backed mindfulness practice that has helped people with MS, stroke, Parkinson's, and chronic pain see real improvement. This episode picks up right where part 1 left off, so start there if you haven't listened yet. Dr. Langer breaks down what it means to learn something mindfully instead of absolutely, why judging yourself and everyone around you keeps you stuck, and why the years running together aren't always a bad thing. She also gets personal about turning 40, what she's doing to stay sharp, and why she believes life gets better as you get older.   What You'll Learn in This Episode: Why learning a rule "absolutely" instead of "conditionally" traps you in beliefs that don't fit your life The two-question mindfulness practice shown to reduce chronic pain, MS, stroke, and Parkinson's symptoms Why every negative judgment you make about yourself has an equally true, more generous version How to use AI as a tool without losing your own agency (and the surprising 45-year-old research behind it) Why Dr. Langer believes the goal isn't more years in your life, but more life in your years   Timestamps: (00:00) – Welcome back for part 2 with Dr. Ellen Langer (00:26) – Why investing in your mindset matters beyond just you (00:44) – Learning mindfully vs. mindlessly, and why the rule-writer's perspective matters (01:37) – The tennis racket story: why "the way you do it" isn't the only way (03:01) – The bell that should go off every time you're judgmental (03:47) – Why every judgment has an equally strong, opposite version (05:41) – Why the years blurring together isn't only a sign of aging (06:00) – Stop counting years, start adding life to them (08:00) – "Sticks and stones" had it backwards (09:33) – The label "chronic" and what it really means (10:05) – The two-question exercise that reduced chronic symptoms in real studies (11:59) – How to try the exercise yourself, step by step (13:38) – AI as a tool: the brilliant graduate student metaphor (14:03) – The 45-year-old research on self-induced dependence (17:28) – What Ellen wishes women understood about getting older (20:07) – What Ellen does to stay sharp and creative   Links to great things we discussed:  The Mindful Body Function Health Uplift App Join me on Substack: Wise Woman Method Alli on YouTube Join me for the 90 Day Reset – Build Your Best Fall   I hope you loved this episode!

(0:37)  — YANKEES: The Yankees offense reverts to form while they avoid getting swept by the Blue Jays. (7:16) — METS: The Mets sweep the Nationals and Kodai Senga finds a new role in the bullpen. (11:09) — CALLS: Callers talk Yankees and Mets. (19:50)— TOP 15 NY ATHLETES: The 2022 edition of the top 15 athletes in NY starts with nos. 15-11. (25:40) — SHAUN MORASH: WFAN's Shaun Morash joins the show to recap the Giants preseason opener, expectations for Big Blue and Jaxson Dart's safety. (50:32) — WILL PARKINSON: Will Parkinson from the Turn on the Jets podcast returns to discuss the Jets preseason opener, veteran additions and David Bailey upside. We want to hear your thoughts! Call the listener line at 917-382-1151 and share your message for JJ. Subscribe to NYNY's YouTube Page: https://www.youtube.com/@NewYorkNewYorkwJJ. Follow JJ on Twitter: https://twitter.com/john_jastremski. Follow ‘NYNY' on Instagram: https://www.instagram.com/nynywjj/ Get your tickets for the Badlands Live Show Here: http:// bit.ly/BadlandsLive  Host: John Jastremski Guests: Shaun Morash and Will Parkinson Music: Frontier Learn more about your ad choices. Visit megaphone.fm/adchoices

Kirk and Cam Gibson join us to talk about the Kirk Gibson Foundation for Parkinson's and today's charity golf outing

Over the last 50 years the average life expectancy in NZ has risen by over 10 years .. which some might say is a great success .. but it does put into question our healthspan .. or how well we are actually living. The brain is our most complex organ, and with more of us living longer .. we are seeing more issues related to brain health. Over our lifetimes 1 in 5 New Zealanders will be affected by a neurological disease. That includes Parkinson's Disease, which over 12,000 of us currently live with. Today for our expert feature we're joined by brain expert, and Parkinson's researcher Professor Maurice Curtis. He'll be answering all your Parkinson's related questions.. send them through on 2101 on text or Jesse@rnz.co.nz via email. [picture id="4KBEKCL_maurice2_JPG" crop="16x10" layout="full"]

“We can choose our brain's destiny,” says David Perlmutter, MD. Perlmutter is a Board-Certified Neurologist and six-time New York Times bestselling author whose work focuses on the intersection of neurology, nutrition, and brain health. He is on the Board of Directors of the American College of Nutrition and the Editorial Board of the Journal of Alzheimer's Disease. His books, including the #1 bestseller Grain Brain, has been published in 32 languages and sold over a million copies. Perlmutter lectures globally at leading institutions and has been featured on major media outlets including 20/20, CNN, The Today Show, and Oprah. His new book, Brain Defenders, focuses on the pivotal role of microglia, the brain's immune cells, in protecting, repairing, and reprogramming the brain for lifelong resilience, and is now available for pre-order. 00:00 - Treating the symptoms, not the cause  02:37 - Microglial cells & their evil twin state  05:44 - How metabolism affects the brain  08:00 - Gut bacteria, inflammation, & brain degeneration  11:38 - Why lifestyle beats the APOE4 gene  16:25 - Perlmutter's daily routine 23:55 - Loneliness & oxytocin  26:21 - The effects of long COVID on the brain 32:18 - Glyphosate & other environmental factors  39:20 - Reprogramming microglia & mitochondrial transplants  41:35 - Own your brain's destiny Referenced in the episode:  For more about Perlmutter, visit his website: https://drperlmutter.com/  Alzheimers & UPFs study: https://doi.org/10.1016/j.tjpad.2024.100042  POINTER study - https://jamanetwork.com/journals/jama/fullarticle/2837046  20-week Alzheimer's study:  https://link.springer.com/article/10.1186/s13195-024-01482-z  Golf course & Parkinson's study: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2833716  We hope you enjoy this episode, and feel free to watch the full video on YouTube! Whether it's an article or podcast, we want to know what we can do to help here at mindbodygreen. Let us know at: podcast@mindbodygreen.com. Learn more about your ad choices. Visit megaphone.fm/adchoices

This month we're interviewing a handful of fascinating people as part of our summer ‘Parky Profiles' series.The Parky author, adventurer and cyclist, Lloyd Taylor joins us this week to talk about the journey to writing his best-selling book 'The Kindness of Strangers'. When Lloyd was diagnosed with Parkinson's, he had trouble sharing his news with others. But then, he was invited to join a cycle ride to raise awareness for the disease, having never really been a cyclist before, which resulted in him joining a 60-day relay across Canada and talking about being a Parky every day. He writes about this adventure and what he learnt from it in his book, and gives us a taste of it all in our conversation. Movers & Shakers is brought to you in partnership with Cure Parkinson's.Presented by Rory Cellan-Jones, Gillian Lacey-Solymar, Mark Mardell, Paul Mayhew-Archer and Sir Nicholas MostynProduced by Lulu Goad and Ewan Cameron for PodotMusic by Alex Stobbs Hosted on Acast. See acast.com/privacy for more information.

Rog is joined by Wrexham co-owners Ryan Reynolds and Rob Mac ahead of the new Championship season. Ryan and Rob reflect on the pride and pain of narrowly missing the playoffs last season, how Wrexham has proven it belongs at this level, and why they continue to put their trust in Phil Parkinson to lead the club forward. Plus, which Championship opponents they're most excited to face this season.Check out the Men in Blazers Shop: https://mibcourage.co/4qIb2L1Sign up for our newsletters: https://mibcourage.co/4rA5fGzJoin our Discord! https://discord.gg/9dUpP2pHHUSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

HEALTH NEWS   Peaches Provide Carotenoids With Reported Eye and Skin Benefits, Experts Say Noninvasive brain stimulation may improve Parkinson's nonmotor symptoms and daily activity Popular Erectile Dysfunction Drug Linked to Vision-Threatening Eye Disease How much do nuts matter for blood pressure? This study points to about a handful a day Fructose May Help Ovarian Cancer Cells Spread, Wistar Institute Study Finds

Charles Brenner breaks down what the science actually says about NAD+, separating established findings from the claims commonly made in the longevity space. He explains why NAD levels in tissues may matter more than blood measurements, how metabolic stress, alcohol, inflammation, and other conditions can disrupt the NAD system, and how nicotinamide riboside (NR) compares with niacin, nicotinamide, and NMN. The conversation also covers research on exercise recovery, peripheral artery disease, skin health, infection, and wound healing, along with the limitations of current human evidence. Brenner explains why he advises against IV and subcutaneous NAD+, discusses concerns around NMN quality, and challenges popular sirtuin-centered theories of anti-aging while emphasizing the importance of reproducible human research. Charles Brenner is an NAD metabolism researcher whose work focuses on cellular bioenergetics, vitamin B3 biology, metabolic stress, and the pathways that regulate NAD production and utilization throughout the body. Now based at the University of Helsinki, his research has examined how the NAD system responds to conditions ranging from metabolic and liver disease to mitochondrial dysfunction, inflammation, and neurological stress. His work has also helped advance research into nicotinamide riboside as an NAD precursor and its potential applications in human health. Brenner takes an evidence-first approach to longevity science, distinguishing findings supported by controlled human studies from promising but still unproven mechanisms, animal research, and anecdotal claims.   Brenner Lab — Charles Brenner, PhD https://www.brennerlab.net/   Niagen NR Clinical Studies — Niagen Bioscience https://www.niagenbioscience.com/pages/clinical-studies   Nicotinamide Riboside for Peripheral Artery Disease — Mary M. McDermott et al. https://pubmed.ncbi.nlm.nih.gov/38871717/   This is the PAD study discussed in the episode where NR improved six-minute walking performance.   NOPARK: Nicotinamide Riboside in Early Parkinson's Disease — Haukeland University Hospital / Norwegian Research Team https://clinicaltrials.gov/study/NCT03568968   This is the 400-participant, 52-week Parkinson's trial discussed in the transcript.   Effects of Nicotinamide Riboside in Long COVID — Chao-Yi Wu, Edmarie Guzmán-Vélez, Charles Brenner et al. https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370%2825%2900567-X/fulltext   This is the Long COVID study Brenner references when discussing cognition, fatigue, sleep, and symptom recovery.   NAD+ Metabolome in Alcohol-Related Liver Disease — Richard Parker, Charles Brenner et al. https://pubmed.ncbi.nlm.nih.gov/32766477/   This is the human alcohol-related liver disease research Brenner discusses when explaining disturbed liver NAD metabolism.   Nicotinamide for Skin-Cancer Chemoprevention — Andrew C. Chen et al. https://pubmed.ncbi.nlm.nih.gov/26488693/   This is the major Australian study relevant to Brenner's discussion of oral nicotinamide and skin cancer protection.   Charles Brenner on NAD+, NR vs. NMN & NAD IVs — Dr. Rhonda Patrick / FoundMyFitness https://www.foundmyfitness.com/episodes/charles-brenner   Dr. Mike specifically references Brenner's appearance with Rhonda Patrick during the episode.   Show Notes 00:00 Welcome to the Hart2Heart Podcast 00:58 NAD Basics Explained 02:22 Cellular Role of NAD 03:21 Proven Benefits and Trials 05:24 Inflammation Markers Deep Dive 09:19 Athletes Recovery and VO2 Max 13:52 Does NAD Decline With Age 20:10 Skin NAD and UV Damage 23:40 Who Should Take NR 27:56 Niacin vs NR vs NMN 32:28 NMN Conversion and Quality 35:37 IV and Injection Warnings 42:18 Dosing Timing and Alcohol 46:50 Addiction Claims and Dream Trials 51:39 Parkinsons and Long COVID Data 55:03 Sinclair Critique Revisited 57:05 Stacking Supplements and Metformin 59:58 Wrap Up and Where to Follow   The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to cutting through the noise and uncovering the most effective strategies for optimizing health, longevity, and peak performance. This podcast dives deep into evidence-based approaches to hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise protocols, leveraging sunlight, and de-prescribing pharmaceuticals — using medications only when absolutely necessary. Beyond health science, we explore the intersection of public health and politics, exposing how policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being. Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary  (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as  Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen). If you're ready to take control of your health and performance, this podcast is for you.We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.   Connect with Dr. Mike Hart Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart

Charles Brenner breaks down what the science actually says about NAD+, separating established findings from the claims commonly made in the longevity space. He explains why NAD levels in tissues may matter more than blood measurements, how metabolic stress, alcohol, inflammation, and other conditions can disrupt the NAD system, and how nicotinamide riboside (NR) compares with niacin, nicotinamide, and NMN. The conversation also covers research on exercise recovery, peripheral artery disease, skin health, infection, and wound healing, along with the limitations of current human evidence. Brenner explains why he advises against IV and subcutaneous NAD+, discusses concerns around NMN quality, and challenges popular sirtuin-centered theories of anti-aging while emphasizing the importance of reproducible human research. Charles Brenner is an NAD metabolism researcher whose work focuses on cellular bioenergetics, vitamin B3 biology, metabolic stress, and the pathways that regulate NAD production and utilization throughout the body. Now based at the University of Helsinki, his research has examined how the NAD system responds to conditions ranging from metabolic and liver disease to mitochondrial dysfunction, inflammation, and neurological stress. His work has also helped advance research into nicotinamide riboside as an NAD precursor and its potential applications in human health. Brenner takes an evidence-first approach to longevity science, distinguishing findings supported by controlled human studies from promising but still unproven mechanisms, animal research, and anecdotal claims.   Brenner Lab — Charles Brenner, PhD https://www.brennerlab.net/   Niagen NR Clinical Studies — Niagen Bioscience https://www.niagenbioscience.com/pages/clinical-studies   Nicotinamide Riboside for Peripheral Artery Disease — Mary M. McDermott et al. https://pubmed.ncbi.nlm.nih.gov/38871717/   This is the PAD study discussed in the episode where NR improved six-minute walking performance.   NOPARK: Nicotinamide Riboside in Early Parkinson's Disease — Haukeland University Hospital / Norwegian Research Team https://clinicaltrials.gov/study/NCT03568968   This is the 400-participant, 52-week Parkinson's trial discussed in the transcript.   Effects of Nicotinamide Riboside in Long COVID — Chao-Yi Wu, Edmarie Guzmán-Vélez, Charles Brenner et al. https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370%2825%2900567-X/fulltext   This is the Long COVID study Brenner references when discussing cognition, fatigue, sleep, and symptom recovery.   NAD+ Metabolome in Alcohol-Related Liver Disease — Richard Parker, Charles Brenner et al. https://pubmed.ncbi.nlm.nih.gov/32766477/   This is the human alcohol-related liver disease research Brenner discusses when explaining disturbed liver NAD metabolism.   Nicotinamide for Skin-Cancer Chemoprevention — Andrew C. Chen et al. https://pubmed.ncbi.nlm.nih.gov/26488693/   This is the major Australian study relevant to Brenner's discussion of oral nicotinamide and skin cancer protection.   Charles Brenner on NAD+, NR vs. NMN & NAD IVs — Dr. Rhonda Patrick / FoundMyFitness https://www.foundmyfitness.com/episodes/charles-brenner   Dr. Mike specifically references Brenner's appearance with Rhonda Patrick during the episode.   Show Notes 00:00 Welcome to the Hart2Heart Podcast 00:58 NAD Basics Explained 02:22 Cellular Role of NAD 03:21 Proven Benefits and Trials 05:24 Inflammation Markers Deep Dive 09:19 Athletes Recovery and VO2 Max 13:52 Does NAD Decline With Age 20:10 Skin NAD and UV Damage 23:40 Who Should Take NR 27:56 Niacin vs NR vs NMN 32:28 NMN Conversion and Quality 35:37 IV and Injection Warnings 42:18 Dosing Timing and Alcohol 46:50 Addiction Claims and Dream Trials 51:39 Parkinsons and Long COVID Data 55:03 Sinclair Critique Revisited 57:05 Stacking Supplements and Metformin 59:58 Wrap Up and Where to Follow   The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to cutting through the noise and uncovering the most effective strategies for optimizing health, longevity, and peak performance. This podcast dives deep into evidence-based approaches to hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise protocols, leveraging sunlight, and de-prescribing pharmaceuticals — using medications only when absolutely necessary. Beyond health science, we explore the intersection of public health and politics, exposing how policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being. Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary  (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as  Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen). If you're ready to take control of your health and performance, this podcast is for you.We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.   Connect with Dr. Mike Hart Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart

Episode 26-32 Insulin Resistance- The "Silent Killer" You Probably Have, But Don't Know It Do you have Insulin Resistance? That's a question you should know the answer to. Why? Because Insulin Resistance is linked to nearly every major chronic disease. Diseases such as High Blood Pressure, Diabetes, Alzheimer's, Stroke, Parkinson's, Fibromyalgia, Multiple Sclerosis, Obesity, Heart Disease, and Autoimmune Disorders.  Insulin Resistance is also something very few doctors talk about. Why? I honestly don't know. But what I DO know is this: YOU need to know about Insulin Resistance… AND you need to know how to find out whether or not you have it. This is especially true if you are over the age of 30 as the majority of American adults HAVE Insulin Resistance and don't even know it! On this episode I talk about Insulin Resistance and how to determine if you have it. Give this episode a good listen and, as always, be sure to share it with a friend.  Thanks!  ———————- Want to learn more? Continue the conversation regarding this episode, and all future episodes, by signing up for our daily emails. Simply visit: GetHealthyAlabama.com  Once there, download the "Symptom Survey" and you will automatically added to our email list. ———————- Also, if you haven't already, we'd appreciate it if you'd subscribe to the podcast, leave a comment and give us a rating. (Thanks!!!)  

           * This podcast is for informational and educational purposes only. It is not intended to diagnose or treat any disease. Please consult with your health care provider before making any health-related changes.

Exposure to a highly toxic weedkiller called paraquat is tied to a person's risk of developing Parkinson's disease. Lawmakers in Missouri and other Midwestern states have tried to pass measures banning paraquat. But as the Midwest Newsroom's Luke Nozicka reports, their efforts have stalled this year.

County auditors are recruiting poll workers for the General Election. A new grassroots effort in Clinton is trying to get involved in data center regulations. And an Iowa lawmaker tried to ban a toxic weedkiller tied to Parkinson's disease this year.

  In this episode of Resiliency Radio with Dr. Jill, Dr. Jill Carnahan welcomes renowned neurologist and bestselling author Dr. David Perlmutter to explore the emerging science behind brain health, neuroinflammation, and cognitive resilience. Drawing from his groundbreaking new book, Brain Defenders, Dr. Perlmutter explains how microglia—the brain's immune cells—play a central role in protecting or damaging the brain depending on our metabolism, lifestyle, and environment. Together they discuss why Alzheimer's and Parkinson's disease begin decades before symptoms appear, why inflammation and insulin resistance are major drivers of neurodegeneration, and what we can do today to protect lifelong brain health. Whether you're concerned about memory loss, dementia prevention, or optimizing cognitive performance, this episode offers science-backed strategies to build a healthier, more resilient brain.

Bernie Kosar sits down with Sage Steele for one of the most emotional and inspiring conversations in the show's history. The Cleveland Browns legend opens up about the decade since he and Sage first met at Game 7 of the 2016 World Series, a stretch that took him through a 96-hour coma, cirrhosis, early-onset dementia, a Parkinson's diagnosis, and a liver transplant that nearly did not happen. Bernie shares the almost unbelievable story of his 21-year-old donor, a young man who told his family days before his death that he wanted Bernie to have his liver, and the bond Bernie now shares with the donor's family. He talks candidly about the regenerative medicine he credits with getting his mind back, the concussion culture that told players to hide their injuries, why he has no regrets about the hits, the bankruptcy that reshaped his life, and the faith that carried him through. From the drive and the fumble to a Super Bowl ring, from rock bottom to a second chance, this is Bernie Kosar like you have never heard him. New episodes of The Sage Steele Show every week. Sponsors: Visit https://GoodRanchers.com/SAGE to get $50 off anything on their site. Provide one life-saving ultrasound for just $28 at https://preborn.com/sage. www.Quo.com/SAGE Your $17.76 3-week QuickStart is ready for you! Visit https://www.relieffactor.com/ or call 800-4-RELIEF. BTS on Patreon: http://bit.ly/4nLmOSk The Sage Steele Show is a weekly podcast hosted by former ESPN anchor Sage Steele. Each week, Sage sits down with entertainers, athletes, business people, and politicians to have deep dive personal one on one discussions that enlighten, entertain, and engage. There's a whole big world out there that's not just sports, and Sage wants to talk about all of it. #sagesteelepodcast #sagesteele #podcast Subscribe to the Channel for more Podcasts like this! Listen to the Show on all Podcast Apps "The Sage Steele Show" https://podcasts.apple.com/us/podcast... Follow Sage: https://www.sagesteele.com https://x.com/sagesteele https://www.instagram.com/sagesteele https://www.tiktok.com/@officialsagesteele https://rumble.com/c/SageSteeleProductions

Obstructive sleep apnea affects approximately one in four adults and is especially common among patients with neurologic disorders, including stroke, Parkinson disease, dementia, epilepsy, and neuromuscular conditions. In this episode, Dr. Stephanie Stahl discusses why neurologists should routinely screen for OSA, highlights key symptoms and risk factors, reviews important considerations when interpreting sleep studies, and outlines current treatment options beyond CPAP. Learn how recognizing and treating sleep apnea can improve quality of life, optimize management of neurologic disease, and reduce long-term health risks. In this episode, Aaron L. Berkowitz, MD, PhD, FAAN, speaks with Stephanie M. Stahl, MD, FAASM, author of the article "Obstructive Sleep Apnea" in the Continuum® August 2026 Sleep Neurology issue. Dr. Berkowitz is a Continuum® Audio interviewer and a professor of neurology in the Department of Neurology at the University of California, San Francisco, in San Francisco, California. Dr. Stahl is an Associate Professor of Clinical Medicine and Sleep Medicine Fellowship Program Director at Indiana University School of Medicine in Indianapolis, Indiana, where she also serves as Sleep Laboratory Medical Director in the Division of Pulmonary, Critical Care, Sleep, and Occupational Medicine. Additional Resources Read the article: Obstructive Sleep Apnea Subscribe to Continuum®: shop.lww.com/Continuum Earn CME (available only to AAN members): continpub.com/AudioCME Continuum® Aloud (verbatim audio-book style recordings of articles available only to Continuum® subscribers): continpub.com/Aloud More about the American Academy of Neurology: aan.com Social Media facebook.com/continuumcme @ContinuumAAN Host: @AaronLBerkowitz  Full episode transcript available here Dr Berkowitz: Obstructive sleep apnea is very common. It can cause or contribute to common neurologic symptoms, such as headache and impaired cognition, and it's a risk factor for stroke. And yet, if you're like me, you may not know too much more about sleep apnea than that. Today, I have the pleasure of talking to sleep expert Dr. Stephanie Stahl to learn what every neurologist should know about OSA.  Dr Jones:  This is Dr. Lyell Jones, Editor-in-Chief of Continuum. Thank you for listening to Continuum Audio. Be sure to visit the links in the episode notes for information about earning CME, subscribing to the journal, and exclusive access to interviews not featured on the podcast.  Dr Berkowitz: This is Dr. Aaron Berkowitz. Today I'm interviewing Dr. Stephanie Stahl about her article on obstructive sleep apnea. This article appears in the 2026 Continuum issue on Neurology of Sleep. Welcome to the podcast, Dr. Stahl, and could you please introduce yourself to our audience?  Dr Stahl: Yeah. Thank you for having me. I'm a sleep medicine physician and neurologist and medical director of the Indianapolis Sleep Lab at Indiana University Health. I serve as the director of the Sleep Medicine Fellowship program. I'm faculty advisor for our very first student interest group in sleep medicine at Indiana University School of Medicine. I'm also actively involved in some national leadership roles, including the incoming chair of the American Academy of Sleep Medicine's Education Committee and co-chair of the Academy's Inter-Scorer Reliability Gold Standard Panel. So, I really appreciate this opportunity. I look forward to our discussion.  Dr Berkowitz: Me too, and we appreciate the opportunity too to get to talk to you. You have so much expertise in this area, and I certainly encourage our listeners to look at your article, which is very comprehensive and up to date, and I learned a ton from it. I didn't get much exposure to sleep neurology as a trainee, and I've always worked in academic centers where we have a sleep group and we can refer patients there. So, I have to admit, sleep may probably be the area of neurology I know the least about, and felt like I was learning something new from pretty much every line of your article, and I know our readers will too. So, your article has a lot of excellent detail for our readers on the diagnosis and treatment of this very common condition. But I'd like to keep our interview relatively high level today and focus on the essentials for the practicing general neurologist. So, to start, can you just give us a sense of what obstructive sleep apnea is, and what every neurologist should know about it?  Dr Stahl: Yeah. So obstructive sleep apnea is characterized by either partial or full obstructions in the upper airway. That may sound pretty simple, but this leads to a whole bunch of issues. It leads to oxygen desaturations, arousals from sleep, leading to sleep fragmentation. This can then lead to sympathetic nervous system activation, cerebral hypoperfusion, leading to a whole bunch of symptoms or neurologic conditions.  Dr Berkowitz: Great. And you mentioned this in your article, but just to emphasize, how common is obstructive sleep apnea in the general population?  Dr Stahl: Yeah. So, about a quarter of the general population have obstructive sleep apnea. Much more common in many neurologic conditions.  Dr Berkowitz: Yeah, so very common disorder. We are seeing patients with it quite frequently, whether that's the reason they are seeing us in neurology or not. And this leads to my next question, which is what neurologic symptoms or presenting concerns of a patient should make us think about OSA and the differential diagnosis, and what factors based on the history or the exam or the context would make you suspicious for OSA as the cause of a neurologic symptom? In other words, the patient's presenting with classic symptoms of OSA, and that's why they're seeing a neurologist or seeing a primary care doctor, but is coming for evaluation of, say, headache or other symptoms. And what symptoms would make you think of wanting to consider OSA, and then what aspects of the history or otherwise would make you want to evaluate the patient for OSA?  Dr Stahl: I think a really important takeaway is for neurologists to know that obstructive sleep apnea is very common in neurologic conditions and has that potential to worsen a lot of these conditions or their associated symptoms. And so, it should be on our radar. There are certainly some basic questions and signs and symptoms that we can ask patients about or, or take a look at on exam. And so particular symptoms include snoring. Anybody that snores loudly or frequently, that's a strong risk factor for obstructive sleep apnea. If someone's seeing them stop breathing in their sleep, if they are waking up a lot throughout the night. There are some other symptoms that we may not necessarily attribute upfront to obstructive sleep apnea, such as nocturia, nocturnal reflux, night sweats. There are some daytime symptoms, of course, too, like unrefreshing sleep, daytime sleepiness, morning headaches, an important one in neurology. And then we take a look at the patient's exam. And so, some things that neurologists might want to be thinking about are people with obesity are certainly at a risk for obstructive sleep apnea. But it's also very important to know that someone does not need to have obesity in order to have obstructive sleep apnea. We look at neck size, other morphologic characteristics, such as how much that we can see in the back of their mouth. Can we see their uvula? Does their tongue size appear large in their mouth? And then some other risk factors too, such as male gender, older age, family history, post-menopausal state in women. All that being said, though, sometimes in neurologic conditions, we don't have all of those symptoms or risk factors to be thinking about. And so, in certain neurologic conditions such as stroke where obstructive sleep apnea is very common and has the potential to increase the risk of another stroke, we may need to be thinking about testing these patients even with minimal symptoms or other risk factors.  Dr Berkowitz: That's very helpful. So, you mentioned their headache might be the presenting symptom, right, to a neurologist, and we should certainly be thinking about obstructive sleep apnea as a potential diagnosis, even the cause of the patient's headache, particularly you said patients with morning headache. I often try to think about in patients presenting with, for memory loss, or other cognitive concerns, and that may be due more to inattention from poor sleep, so asking about sleep and symptoms of sleep apnea in those contexts. Are there any other presenting neurologic symptoms not particularly related to sleep? I'm thinking of headache, memory loss, other symptoms that would make you think, "Oh, I should actually screen this patient for sleep apnea also."  Dr Stahl: Yeah, other symptoms to think about in pediatrics, hyperactivity, people that have impaired vigilance, as you alluded to, that poor attention. Sometimes people get misdiagnosed with ADHD, and it's actually just a manifestation of obstructive sleep apnea.  Dr Berkowitz: You alluded to this, Dr. Stahl, that stroke, for example, patients are at higher risk of developing sleep apnea as a result of stroke, and it's also a risk factor for stroke. What other neurologic conditions, primary neurologic diseases, put patients at a higher risk of OSA? And again, similar to the last question I asked you, what are some clues that we should evaluate for? We might be following a patient for their post-stroke care over time and not necessarily thinking about diagnosing a separate condition in them since we're following them for their stroke or their degenerative disease. What are the conditions that put patients at a higher risk of OSA as a result of the condition, and then when would you think about screening them for it?  Dr Stahl: Some particular neurologic conditions where obstructive sleep apnea are very common, in addition to stroke and, and TIA, include Parkinson disease. It can worsen a lot of the motor, cognitive symptoms, sleep disruption that we can see in Parkinson disease. Very common in all causes of dementia, but in particular Alzheimer disease and Lewy body dementia. Very common in neuromuscular conditions. We should definitely have obstructive sleep apnea and all forms of sleep-disordered breathing high on our radar. In conditions like myotonic dystrophy. Charcot-Marie-Tooth is another one where obstructive sleep apnea is very common. Myasthenia gravis, it can worsen the symptoms of that. In particular, a pearl is if somebody has morning weakness in myasthenia gravis, obstructive sleep apnea should be high on your radar. And also, as you mentioned, any forms of headaches. There are some other things too. If somebody has poor seizure control, especially nocturnal seizures, you might have obstructive sleep apnea on your radar as well.  Dr Berkowitz: So, I think you've covered essentially every category of neurologic disease, right? We have cerebrovascular, movement, neurodegenerative, neuromuscular, epilepsy, all conditions where either the disorder itself, such as stroke or the, correct me if I'm wrong, the neurodegenerative disease puts the patient at risk. Or the patient may be at risk for exacerbations of their disease, as you mentioned in myasthenia. I love that pearl. Not fatiguable at the end of the day, but if the patient with myasthenia is telling you they're feeling weaker at the beginning of the day, then think about obstructive sleep apnea and that obstructive sleep apnea worsening control of epilepsy due to poor sleep. So really a lot of bidirectional interactions with this common condition. Okay, so if we're concerned about obstructive sleep apnea, again, myself, a general neurologist speaking perhaps on behalf of other general neurologists, we see a patient with headache or reporting memory loss that we find to be impaired attention, or we see exacerbation of their underlying primary neurologic disease. As you mentioned, we think, "Oh, I've listened to this podcast. I've read Dr. Stahl's article. I should probably be thinking about OSA in this patient, and I should order a sleep study." Now, I admit when I get the sleep study back, I scroll to the bottom, I see they do have obstructive sleep apnea, I'm going to send them over to a sleep specialist. But for the general neurologist, what are some high-yield pearls and some pitfalls to be aware of when we get sleep studies for obstructive sleep apnea, and we are looking at the results? Dr Stahl: The first thing is to understand that there are two main types of sleep studies: in-lab polysomnography and home sleep apnea test. In-lab studies are typically what we consider the more accurate type of study. Main reason for that is that we have EEG, so we can see if someone is awake versus asleep. Most home sleep apnea tests do not utilize EEG, and so when we're looking at respiratory events, apneas or hypopneas, we're looking at over the total recording time rather than the total sleep time. So, we know we're going to capture some time where a person is awake, where we don't have sleep apnea events, and that can be a big amount of time in people with insomnia, poor sleep efficiency. And as a result of that, it can lead to an underestimation of the apnea-hypopnea index. That's really important for people to understand that that means we can end up with a false negative home sleep apnea test, or it can put them in a category of lower severity than what they actually have. And so, if you get a home sleep study report back that's negative for sleep apnea and you remain concerned, you need to go on to do an in-lab study, where about twenty to fifty percent of people will go on to have a positive in-lab study. You can also get false positives with home sleep apnea tests too, and so ideally, we should only be doing home sleep apnea tests in people that are at high risk of having obstructive sleep apnea to decrease our chance of false positive study. When we get that sleep study report, what's important to take a look at? So the main number that we look at currently is the apnea-hypopnea index. The number of apneas, which are full obstructions in that upper airway, or hypopneas, partial obstructions in the upper airway where either there's an oxygen desaturation or an arousal associated with that. Less than five is considered to be normal. Anything five or more gives them a diagnosis of obstructive sleep apnea, and then we stratify them based on the AHI. But it's important to take a look at more than just the apnea-hypopnea index. And while my eyes too on various reports like echocardiograms want to jump to the impression, it is important to take a look at that full report, see what their oxygen levels averaged and what they dipped down to. The arousal index, which is how many times a patient may have woken up briefly throughout the night. Take a look at the histogram, usually an image at the bottom of their report that shows what sleep fragmentation may have been like so that you can take that all in and make that decision. How important are these study findings, and is this a person that would benefit from treatment?  Dr Berkowitz: That's a fantastic overview of sleep studies and some of the highlights to look out for, even if we won't be understanding every detail as you would to know most importantly the caveats about home sleep testing having a fairly high percentage of false negative and false positive results. So being wary if our suspicion is high, and that test is normal or inconclusive to get an in-lab sleep study. And if our suspicion is low or maybe we haven't ordered the test and the patient has had it done elsewhere, and the history doesn't really match up to know that there are false positives on the home studies as well, and again, an in-lab study to settle the diagnosis. Is that right?  Dr Stahl: Yes.  Dr Berkowitz: Okay. Now, for most neurologists, probably if we diagnose OSA, we will be referring the patient to a sleep specialist like yourself for treatment. I think we're all familiar with CPAP and patients being on CPAP. Your article mentions a number of treatment modalities I admit I have not heard of before or maybe heard of in passing, acknowledging most general neurologists are not going to be prescribing or knowing with the nuance that you do as an expert how to decide which treatment a patient would most benefit from or most qualify for. So, can you just give us a broad overview, again, for the general neurologist acknowledging we might see a patient whose past medical history says OSA being treated with fill in the blank. What are the different treatment modalities, and how do you think, just so we can learn from you in broad brush strokes, about particular treatments for particular patients?  Dr Stahl: As you mentioned, most people are familiar with positive airway pressure or PAP therapy, and that does remain our most efficacious treatment. The way I explain it to patients is why PAP therapy is the most effective treatment is it's the only treatment that can take all of the tissues of that upper airway and open them up. Whereas all of our other treatments, we're going to target smaller spaces of that upper airway. So, our first option is if we can get somebody on PAP therapy, we know that that's going to be the best option for the majority. PAP therapy works by basically acting as an air splint to open up the air tissues. Know that masks are not interchangeable. There are masks that cover the nose and go over the nose and mouth and under the nose. Full face masks that cover the nose and mouth, they do typically require higher pressures, also tend to be less comfortable for a lot of patients as well. In addition to different PAP masks, there's different modalities of positive airway pressure therapy too. There are machines that auto-adjust, some that provide fixed pressure, bi-level PAP that provides a higher inspiratory pressure, lower expiratory pressure. Then outside of PAP therapy, there are, as you alluded to, a lot of options and more, continuing to come down the pipeline as well. Mandibular advancement devices or a form of oral appliances has been around for a while. This is device that somebody wears in their mouth. It's preferably customized for their teeth and titratable, meaning that they can make adjustments that pulls their mandible forward in relation to the maxilla in order to pull those tongue tissues further away from the back of the upper airway. That's ideally managed by a qualified sleep dentist or someone that specializes in oral appliance management. Other treatments include surgical options, including hypoglossal nerve stimulation, which is an implanted device that causes the tongue to protrude repetitively throughout their sleep period to hopefully open up the airspace. There's some other surgical options too that open up various places of the upper airway. There's a daytime treatment of obstructive sleep apnea, transoral neuromuscular electrical stimulation that changes the muscle fiber type of the tongue. And then there's some adjunctive treatments that can be helpful too, such as positional therapy, oral facial myofunctional therapy that helps a person breathe better through their nose and may help train the upper airway muscles.  Dr Berkowitz: Great. Well, that's a very helpful overview, and again, I refer our listeners to your article, which talks about all of those modalities in very comprehensive detail. So, Dr. Stahl, as we wrap up our conversation, you have a captive audience of neurologists and neurology trainees here. What would you like to leave us with that every neurologist should know about obstructive sleep apnea?  Dr Stahl: The most important, again, is for neurologists to know that obstructive sleep apnea is so common in your patient population, and it can have a significant negative impact on quality of life and health, including many neurologic conditions. And at the same time, obstructive sleep apnea is very treatable. We have so many options nowadays that we can usually get someone onto adequate treatment. And treatment has that potential to improve several neurologic symptoms and disorders, even at times when you don't think that there's an opportunity to improve symptoms such as say in, headache. So, neurologists really should be screening for signs and symptoms of obstructive sleep apnea, as well as considering testing in high-risk, potentially asymptomatic or minimally symptomatic patients.  Dr Berkowitz: That's a fantastic overview of some of the many pearls that you shared with us today, as well as in your article. So, thank you so much again. Today, I've been interviewing Dr. Stephanie Stahl about her article on obstructive sleep apnea. This article appears in the August 2026 Continuum issue on neurology of sleep. Be sure to check out Continuum Audio episodes from this and other issues. And thank you so much to our listeners for joining today, and thank you again, Dr. Stahl.  Dr Stahl: Thank you again for having me.  Dr Monteith: This is Dr. Teshamae Monteith, Associate Editor of Continuum Audio. If you've enjoyed this episode, you'll love the journal, which is full of in-depth and clinically relevant information important for neurology practitioners. Use the link in the episode notes to learn more and subscribe. AAN members, you can get CME for listening to this interview by completing the evaluation at continpub.com/audioCME. Thank you for listening to Continuum Audio.  

Do you ever think about all that's involved in just swallowing a bit of breakfast taco or a sip of coffee?

Broadcast from KSQD, Santa Cruz on 8-06-2026: >ul> An emailer with persistent nine-month nerve damage in her right leg after a hysterectomy asks whether peptides could help. Dr. Dawn attributes the injury to lithotomy positioning during surgery, then reviews the main nerve-regeneration candidates in the FDA peptide review pipeline: BPC-157 (Body Protection Compound, strong rat data on sciatic nerve recovery with thicker myelin sheaths), intracellular sigma peptide (targets glial scar CSPGs blocking CNS regrowth), C3 peptide 156-181, GHK-Cu (copper peptide, upregulates nerve growth factor and neurotrophin-3), self-assembling hydrogel scaffolds for bridging nerve gaps, ARA-290/cibinetide (an erythropoietin fragment with early small fiber neuropathy trial data), and Semax (used internationally for stroke rehab). She adds standard functional-medicine adjuncts: alpha-lipoic acid, methylated B12, and methylfolate at high doses for six months. An emailer asks about safe features when buying an infrared sauna. Dr. Dawn covers three concerns: EMF exposure (look for shielded/grounded heaters testing under 1 milligauss at seat level, avoid unshielded Wi-Fi and Bluetooth panels); VOC off-gassing (avoid plywood, particle board, and MDF because of formaldehyde and benzene release, and avoid Western red cedar and pine because of high terpene emissions and instead choose poplar, basswood, or eucalyptus); and avoid built-in oxygen ionizers, which produce ozone as a coronal-discharge byproduct that irritates airways and generates secondary oxygenated VOCs. Dr. Dawn covers the surprisingly long list of medications that raise estrogen in middle-aged men—including nearly all antidepressants and antiepileptics, statins, NSAIDs (specifically naproxen and indomethacin but not ibuprofen), most blood pressure medications, PPIs, H2 blockers, Parkinson's drugs, antihistamines, and muscle relaxants. She recommends annual monitoring of the estrogen-to-testosterone ratio and offers rebalancing options: topical chrysin (blocks aromatization), indole-3-carbinol, calcium D-glucarate (blocks enterohepatic estrogen recirculation), soy (competitive receptor inhibition), and grape skin extract. The first mRNA-based flu vaccine was approved this week for adults 50 and over. Beyond the 27% improvement in seasonal efficacy over conventional shots, the strategic advantage is manufacturing speed. This will be critical when or if bird flu mutates to respiratory human transmission. Since mRNA vaccine can be reprogrammed from a new viral sequence in weeks versus the three-to-four-month growth cycle for conventional flu vaccines, rapid response can save lives. But mRNA vaccine side effects include more injection-site pain and fatigue - more like a tetanus shot than a traditional flu shot.. A Spanish prospective study of chemicals affected puberty in the young studied 500 girls followed from ages 7-10 and again at 14-16 used urine chemical measurements as objective exposure markers rather than food diaries. Ethylenethiourea, a metabolite of dithiocarbamate fungicides used heavily on strawberriess,was associated with earlier menarche, while a chlorpyrifos metabolite was associated with delayed menarche. this latter effect was more pronounced in overweight girls whose fat tissue concentrated the compound. Dr. Dawn recommends organic strawberries and keeping children away from fumigated fields. University of Pennsylvania School of Dental Medicine researchers developed a chewing gum from lablab beans containing the natural antiviral protein FRIL, which reduced oral HPV by up to 93% in samples from head and neck squamous cell carcinoma patients. The gum also suppressed Fusobacterium nucleatum and Porphyromonas gingivalis, oral bacteria that promote cancer recurrence. Michigan State University's Hamburger lab studying delphinium (larkspur) alkaloids joined forces with Tomáš Pluskal's Czech Academy of Sciences lab studying wolfsbane (monkshood) after meeting at a Barcelona conference. Together they mapped the biosynthetic assembly line for aconite—an alkaloid with valuable applications against malaria, pain, cancer, and agricultural pests but impossibly slow to extract from source plants—and cloned the pathway into tobacco, which grows aggressively and produces large quantities of the compound. An emailer named in the message asks about an incidentally-discovered enlarged aorta on CT. Dr. Dawn notes it officially becomes an aneurysm at 4 cm (annual monitoring) or 5 cm (six-month monitoring), with smoking cessation critical since tobacco directly weakens the aortic wall. She describes the "zipper of fire" back pain of dissection versus catastrophic rupture, and notes Medicare covers a one-time screening ultrasound for ever-smokers over 65.

Will Parkinson joins Ty Butler to talk about the expectations for the Jets & Aaron Glenn, as well as getting into news around the NFL! Plus, Sideline to Sideline. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Health is not the absence of disease. I feel strongly about this, and I want to make the case for it today. In this episode I share why I believe health is not binary. Your physical health being compromised does not mean your health as a whole is gone. It means one dimension is under strain. And there are other dimensions still available to you. I have coached women navigating cancer, Parkinson's, ALS, and many other serious diagnoses. I would not have been doing that work if I believed the diagnosis was the final word on what someone was capable of. A diagnosis tells you what you are dealing with in one dimension of your health. It does not tell you who you are. How you show up in the face of what you are dealing with is everything. That is the real measure of health. Want everything in one place? Join me on Substack for real talk, deeper insights, and the community you didn't know you needed — at https://courtneytownley.substack.com  #GraceAndGrit #HealthMindset #MidlifeWomen #Diagnosis #DeepHealth #WomensWellness #SelfLeadership #Resilience #MidlifeHealth #IntentionalLiving

RUNDOWN Mitch and Hotshot Scott dissect a trade deadline that produced more shrugs than shockwaves, debating whether the Mariners actually bought or simply trimmed payroll. They weigh the additions of Taylor Ward and Seranthony Domínguez, the Luis Castillo trade, and why Seattle's playoff hopes still rest on Julio Rodríguez, Cal Raleigh, and the hitters already in uniform before wrapping up with birthday trivia. Joe Doyle and Brady Farkas debate whether Jerry Dipoto did enough at the deadline, breaking down Taylor Ward, Seranthony Domínguez, Luis Castillo, and the decision to keep George Kirby and Logan Gilbert. They also examine Seattle's lineup questions and what the club's quiet deadline reveals about its future. Scott Spiezio recounts how a devastating back injury with the Mariners sent his life into a spiral of depression, addiction, and personal collapse. The former World Series hero opens up about alcohol, cocaine, failed relationships, and the long road that inspired his memoir, The Hardest Comeback. Scott Spiezio shares the remarkable turnaround that followed baseball's darkest chapter, describing liver failure, sobriety, restored family relationships, and the faith that transformed his life. Eight years sober, he explains why helping others has become a greater victory than any championship.   GUESTS   Brady Farkas | Host, Refuse to Lose podcast Joe Doyle | MLB analyst, Over-Slot Scott Spiezio | Former Seattle Mariners Infielder & Author, The Hardest Comeback   TABLE OF CONTENTS   0:00 | Mariners Stand Pat as the Trade Deadline Comes and Goes. 25:30 | Mariners No-Table: Joe and Brady Break Down Seattle's Deadline Gamble. 45:56 | Scott Spiezio Part 1: From World Series Hero to Addiction—and Back Again. 1:05:38 | Scott Spiezio Part 2: Redemption Arrives After Baseball's Darkest Detour. 1:218:00 | Other Stuff: 16-year-old Santa Cruz lifeguard's heroic ocean rescue, Kyle Shanahan crash cover-up questions, Ricky Pearsall out for the season as Deebo Samuel returns to San Francisco, Ahman Green reveals Parkinson's diagnosis, Tony Romo placed on leave by CBS, Shohei Ohtani card sells for $11 million, Eric Bieniemy's wife shot by their son, new allegations in the J.P. Morgan/Lorna Hajdinj lawsuit, Donna Mills joins OnlyFans. HEADLINES Bride-to-be accused of setting Utah church on fire the night before her wedding, Minnesota man charged for using homemade spike strips to keep kids off his lawn, FCC approves giant space mirror to provide sunlight on demand, Vietnamese doctors perform nation's first successful penis transplant. RIPS Billy Ray Smith Jr. (64), Vincent Pastore (80), Glen Hansard (56).

Viagra's Cancer Signal, TV's Toll on Your Brain, Heat and Accelerated Aging, and a New Way to Flush Your Brain Explained Viagra's Active Ingredient May Block Cancer From Spreading A study published in Cancer Research from the Weizmann Institute of Science, in collaboration with Clalit and the U.S. National Cancer Institute, found that sildenafil, the active ingredient in Viagra, may interfere with cancer cells' ability to metastasize by disrupting how they regulate cholesterol, a resource tumors need to detach and invade new tissue. The team combined mouse models and human cell cultures with more than twenty years of medical records covering roughly five million people, and found better survival outcomes among about forty thousand cancer patients who had taken sildenafil before diagnosis. Researchers also flagged a possible combination effect with statins. Host Dave Asprey breaks down why this cheap, off-patent drug class deserves more attention than it's getting, and where it fits alongside his own longevity protocol. Source: https://www.healthline.com/health-news/viagra-may-stop-cancer-from-spreading-study ~~ Heavy TV Watching In Midlife Tied To Alzheimer's-Related Brain Changes A nearly twenty-four-year study published in Alzheimer's & Dementia followed more than 1,700 adults, tracking TV habits in their early fifties and scanning their brains in their mid-seventies. Men who watched more TV showed greater white matter damage and smaller frontal and occipital lobes, while women showed no such association. Critically, people with desk jobs that kept them sedentary all day did not show the same brain changes, and the TV association held even after adjusting for exercise levels. Host Dave Asprey unpacks why passive screen time, not sitting itself, may be the real driver here. Sources: https://www.the-independent.com/life-style/tv-time-linked-alzheimers-study-b3023054.html https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/alz.71582 ~~ Ambient Heat Exposure Linked To Faster Biological Aging A Science Advances study of 3,686 older adults linked neighborhood-level heat index exposure to accelerated biological aging using DNA methylation clocks. Short-term heat exposure moved one clock significantly, while exposure sustained over a full year or six years moved all major clocks, with extreme-caution heat days tied to nearly a three-year jump in one aging measure and a five percent faster overall aging pace on another. Researchers point to inflammation and stress signaling as likely drivers. Host Dave Asprey explains why this is a fundamentally different kind of heat story than the sauna and cold-plunge conversation biohackers are used to. Source: https://www.science.org/doi/10.1126/sciadv.adr0616 ~~ Industrial Chicken Farming May Be Accelerating The Spread Of Drug-Resistant Bacteria A genomic analysis of nearly 2,800 bacterial samples from chickens and wild birds across thirty countries, published in PNAS and covered by The Guardian, found a roughly hundredfold increase in Campylobacter strain transitions between wild birds and farmed chickens since 1900. Global chicken populations have grown sevenfold since the 1960s to about 27 billion birds, and researchers identified genetic adaptations tied to antimicrobial resistance developing inside that population. Sixty to eighty percent of human Campylobacter infections trace back to raw chicken, with links to post-infectious IBS in some cases. Host Dave Asprey connects the dots between industrial farming density and the gut-health stakes for anyone who eats chicken. Sources: https://www.theguardian.com/food/2026/jul/27/industrial-chicken-farming-accelerating-spread-of-diarrhoea-bacteria-study-finds https://doi.org/10.1073/pnas.2609969123 ~~ VA Researchers Develop Breathing-Based "Brain Flush" For Parkinson's And Alzheimer's VA researchers led by Dr. Henry Lin found a way to trigger the brain's glymphatic clearance system, normally active during deep sleep, in people who are awake, using alternating puffs of five percent carbon dioxide and room air every thirty-five seconds. In a study of thirty Parkinson's patients and thirty-three healthy controls, a single thirty-minute session produced measurable increases in blood levels of beta-amyloid, alpha-synuclein, and other waste proteins associated with neurodegeneration. The VA's Technology Transfer Program is now developing a patent and prototype device. Host Dave Asprey explains why this gives breathwork protocols a real physiological mechanism instead of just a hunch. Source: https://www.research.va.gov/currents/0426-Exciting-new-treatment-being-developed-for-Parkinsons-Alzheimers.cfm ~~~ This episode is designed for biohackers, longevity enthusiasts, and high-performance listeners who want mechanism-level insights into an overlooked cancer drug repurposing story, the real difference between passive and active screen time, a new angle on heat as a biological stressor, the hidden gut-health cost of industrial poultry farming, and a breathing technique that may unlock your brain's own detox system. Host Dave Asprey connects clinical research, large-scale genomic data, and translational neuroscience into practical frameworks for improving longevity, gut health, and brain performance. New episodes every Tuesday, Thursday, Friday, and Sunday. Keywords: sildenafil cancer metastasis, Viagra cancer research, cholesterol cancer cells, PDE5 inhibitor longevity, TV Alzheimer's risk, screen time dementia, white matter brain aging, passive sedentary behavior brain, ambient heat epigenetic aging, DNA methylation clock, heat index biological aging, industrial chicken farming bacteria, Campylobacter antibiotic resistance, foodborne illness IBS, glymphatic system brain flush, CO2 breathing brain detox, Parkinson's Alzheimer's treatment, VA brain research, biohacking news 2026, Dave Asprey, The Human Upgrade Thank you to our sponsors! - Suppgrade Labs | Get real restorative sleep with Quiet Mode. Use code DAVE15 at shopsuppgradelabs.com. - Timeline | Visit timeline.com/dave to learn more about Mitopure and get 20% off your first order for a limited time. - iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE Resources: • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Intro 00:19 – Story #1: Viagra & Cancer 02:01 – Story #2: TV Watching & Brain Aging 03:16 – Story #3: Heat Exposure & Biological Age 04:46 – Story #4: Chicken Farming 06:34 – Story #5: CO2 Therapy & Brain Detox See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.