Podcasts about Biohacking

Most people think aging starts with wrinkles, gray hair, or memory loss. It doesn't.Aging starts when your legs begin to weaken, long before you notice it.In this video, you'll learn why your leg muscles age faster than the rest of your body, how damaged mitochondria silently drain your strength, and why traditional solutions like exercise and protein stop working after 40.You'll also discover the one cellular process that controls muscle aging, why it shuts down with age, and how targeted support can turn it back on.Chapters00:00 – Why weakness is the first real sign of aging01:28 - Mitophagy and why it shuts down with age02:30 - Why exercise and protein won't help03:55 - The real problem doctors and trainers miss04:28 - The compound that turns mitophagy back on05:22 - Why most people can't produce it enough naturally05:40 - The gut bacteria problem explained06:09 - How researchers solved the bottleneck06:56 - Human studies and muscle strengthThank you to our sponsors! -IGNITON | Head over to Igniton.com and use code DAVE for an exclusive 15% off your first order.-AirDoctor | Go to https://airdoctorpro.com/daveasprey and save up to $300 on Air Purifiers.Resources: • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Connect with Dave Asprey!Website: https://daveasprey.comTikTok: https://www.tiktok.com/@daveaspreyofficialInstagram: https://www.instagram.com/dave.asprey/Facebook: https://www.facebook.com/Daveaspreyofficial/X: https://x.com/daveaspreyYouTube: https://www.youtube.com/c/daveaspreybprThe Human Upgrade Podcast: Instagram: https://www.instagram.com/TheHumanUpgradePodcast/ Facebook: https://m.facebook.com/Thehumanupgrade/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In the late 1990s, a strange carbon molecule quietly delivered the single longest lifespan extension ever recorded in mammals. The rats lived about 90% longer, and almost no one was paying attention. This episode breaks down what that molecule is, why it works, and how it may upgrade mitochondria, sleep, and human performance when used correctly. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Chris Burres, founder and chief scientist of MyVitalC and the original long-term manufacturer of carbon 60. Chris has produced this Nobel Prize–winning molecule since the early 1990s, supplying research institutions around the world years before it ever entered the biohacking space. He explains how carbon 60 behaves differently from traditional antioxidants, why stability and concentration used to be major problems, and how modern manufacturing finally made real-world use possible. Chris is also a published author, longevity summit host, patent holder, and longtime science communicator who brings rare clarity and humor to complex biology. Dave and Chris explore how carbon 60 interacts with mitochondria, oxidative stress, metabolism, and electrical signaling in the body, and where it fits alongside ketosis, nootropics, supplements, and functional medicine strategies. They also unpack why improving mitochondrial function often shows up first as better energy and sleep optimization, and how that foundation supports longevity, brain optimization, and Smarter Not Harder performance. Along the way, Dave shares his own early experience with C60, how he uses it today, and why it now shows up even in his Danger Coffee stack. You'll Learn: • Why carbon 60 produced the longest longevity result ever recorded in mammal studies • How mitochondrial efficiency shapes energy, sleep, and human performance • What makes C60 a selective antioxidant instead of a blunt one • Why purity, concentration, and stability determine whether a supplement works • How carbon 60 fits into biohacking stacks built around ketosis and metabolism • What users report first, from focus and resilience to deeper sleep • Why mitochondrial health underpins long-term anti-aging strategies • How to think about supplements through a Smarter Not Harder lens Dave Asprey is a four time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Affiliates: Vibrant Blue Oils | Grab a full-size bottle for over 50% off at https://vibrantblueoils.com/dave. ECHO Water | Go to http://echowater.com/dave and use code DAVE10 for 10% off your ECHO Flask. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: carbon 60 podcast, C60 longevity science, biohacking mitochondria, mitochondrial optimization podcast, anti-aging supplements science, human performance longevity, selective antioxidant mitochondria, sleep optimization biohacking, brain optimization supplements, nootropics longevity stack, ketosis metabolism longevity, functional medicine mitochondria, oxidative stress longevity, carbon 60 supplement science, MyVitalC podcast, Chris Burres interview, Dave Asprey biohacking, Danger Coffee stack, Smarter Not Harder longevity, Nobel Prize molecule longevity, mitochondrial health podcast Resources: • Get a 30% discount on your next purchase of ESS60 at: https://www.myvitalc.com/pages/humanupgradeod?ref=humanupgrade • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Join My Low-Oxalate 30-Day Challenge: https://daveasprey.com/2026-low-ox-reset/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com Timestamps: 0:00 – Introduction & C60 Discovery 4:04 – The Molecule & Nobel Prize 8:27 – Quantum Properties & Superconductivity 11:16 – Rat Longevity Study Results 14:33 – Selective Antioxidant Properties 15:51 – User Experience & Timeline 18:15 – Biological Age Testing 21:33 – Why Oil & Product Development 23:32 – Mechanism of Action 28:13 – Biohacker Discovery Story 30:03 – FDA & Supplement Regulation 33:50 – Migraines & Clinical Observations 37:53 – Athletic Performance 40:43 – Stacking & Contraindications 45:57 – Skincare Product 50:43 – Who Benefits Most 1:00:37 – Mitochondria & Consciousness 1:02:03 – Where to Buy & Closing See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Aging is not something Zoltan Istvan plans to accept quietly. He wants to treat death like a technical bug, rewrite the rules of biology, and turn California into the global test bed for radical human upgrades. From cyborg implants to AI driven longevity science, this episode explores what happens when a candidate for governor openly argues that humans should evolve beyond their biological limits and take control of how long and how well they live. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Zoltan Istvan, a leading transhumanist, futurist, longevity advocate, and current candidate for Governor of California. Zoltan has spoken at Parliaments and Senates around the world, appeared on The Joe Rogan Experience, consulted for the US Armed Forces, and served as a correspondent for The New York Times. He has addressed the World Bank, the World Economic Forum, and the UK Parliament, and his work has influenced world leaders while shaping global conversations on AI, liberty, and human enhancement. Trained in philosophy and ethics at Columbia University and the University of Oxford, Zoltan brings rare depth to the intersection of technology, biology, and governance. Together, they explore whether aging should be classified as a disease, why regulation is slowing breakthroughs in longevity science, and how California could become ground zero for anti-aging innovation. They debate biology versus machine integration, open source technology versus centralized control, and what morphological freedom really means when enhancement technologies move faster than policy. The discussion spans mitochondria, neuroplasticity, brain optimization, stem cells, organ printing, implants, and the ethical risks of surveillance, algorithmic persuasion, and unchecked AI. This episode is essential listening for anyone serious about biohacking, hacking human performance, longevity, metabolism, functional medicine, anti-aging strategies, supplements, nootropics, ketosis, fasting, carnivore frameworks, sleep optimization, and living Smarter Not Harder in a world increasingly shaped by AI and technology, ideally with a cup of Danger Coffee in hand. You'll Learn: • Why aging may be a solvable problem rather than an unavoidable fate • How politics and regulation influence access to longevity and anti-aging therapies • The real tradeoffs between biological upgrades and machine integration • Why mitochondria, neuroplasticity, and brain optimization matter in human enhancement • How AI and surveillance technology threaten cognitive and biological autonomy • What morphological freedom means for the future of medicine and personal choice • Why open source approaches to biohacking could protect liberty and innovation • How Smarter Not Harder strategies support longevity in a rapidly evolving world Dave Asprey is a four time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Thank you to our sponsors! BEYOND Conference 2026 | Register now with code DAVE300 for $300 off at https://beyondconference.com/ MASA Chips | Go to https://www.masachips.com/DAVEASPREY and use code DAVEASPREY for 25% off your first order. GOT MOLD? | See what's in your air and save 10% with code DAVE10 at http://gotmold.com/shop EMR-Tek | Get 40% off EMF protection with code DAVE at https://www.emr-tek.com/DAVE Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: transhumanism podcast, human cyborg future, biohacking transhumanism, longevity technology podcast, anti-aging technology, human enhancement podcast, cyborg implants future, AI human evolution, aging as a disease, radical longevity science, human performance future, brain optimization technology, mitochondria longevity science, neuroplasticity enhancement, biohacking longevity politics, California longevity policy, morphological freedom body, human augmentation debate, AI risk humanity, surveillance technology health, open source biohacking, stem cell longevity future, organ printing technology, functional medicine future, metabolism longevity science, ketosis fasting longevity, nootropics brain optimization, supplements longevity science, carnivore diet longevity, sleep optimization performance, Dave Asprey transhumanism, Zoltan Istvan podcast, futurist longevity interview, governor cyborg policy, technology immortality debate Resources: • Learn More About Zoltan's Work At: https://zoltanistvan.com/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Join My Low-Oxalate 30-Day Challenge: https://daveasprey.com/2026-low-ox-reset/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com Timestamps: 0:00 – Introduction 3:51 – What Is Transhumanism 8:15 – Biology vs Technology 12:53 – Government & Regulation 20:43 – Running for Governor 26:13 – Social Media & Kids 30:18 – Life Extension & Upgrades 38:59 – Defining Humanity 46:12 – Consciousness & Uploading 49:27 – Religion & Society 58:02 – AI Existential Risk 1:02:57 – Space & Future Enhancement See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode of the Holistic Dentistry Podcast, Dr. Sanda Moldovan interviews Dr. Sri Mummaneni, MD, MPH, who discusses the connection between longevity and spirituality. They explore how personal experiences, self-awareness, and daily habits can enhance well-being. Dr. Mumaneni emphasizes the importance of listening to one's body, understanding burnout, and integrating holistic practices into health care. The conversation also touches on the significance of oral health and community support in achieving overall wellness. Want to see more of The Holistic Dentistry Show? Watch our episodes on YouTube! Do you have a mouth- or body-related question for Dr. Sanda? Send her a message on Instagram! Remember, you're not healthy until your mouth is healthy. So take care of it in the most natural way.  Key Takeaways: Longevity and spirituality are interconnected. Personal health journeys can lead to new insights in medicine. Self-awareness is crucial for living your best life. Listening to your body can prevent burnout. Daily habits like breathing and grounding improve well-being. Sunlight exposure is essential for health. Biohacking should support authenticity and spirituality. Oral health reflects overall well-being. Clenching and grinding may indicate deeper issues. Community support enhances health programs. Guest Info Website abundancehealth.com IG : @drsrimd Connect With Us:  AskDrSanda | YouTube BeverlyHillsDentalHealth.com | Instagram  DrSandaMoldovan.com | Instagram  Orasana.com | Instagram

Why does modern motherhood feel so hard — even when you're doing everything “right”?In this episode of Healthy As A Mother, we explore a powerful lens for understanding hormones, fertility, pregnancy, postpartum, and burnout: humans are animals — and modern life is not designed for our biology.From nervous system dysregulation and chronic stress to fertility struggles, postpartum depletion, and emotional overwhelm, this conversation reframes modern motherhood as a biological mismatch, not a personal failure.We cover:The “human animal in captivity” conceptWhy community is essential for mothersSunlight, sleep, movement, and hormonal healthNervous system overload, modern stress, and burnoutWhy self-care isn't indulgent — it's biological necessityThis episode is for women and mothers who feel like something about modern life, health, and motherhood just isn't working — and want a deeper, root-cause understanding.00:00 Introduction: The Human Animal02:05 Humans as Animals05:10 Animals in Captivity09:15 The Continuum Concept14:05 Biohacking vs Nature18:20 Hormones, Detox & Toxic Load22:45 Genetics & Sensitivity27:10 Evolution or De-Evolution31:30 The Loss of the Village36:20 Reciprocity & Support40:55 Parenting, School & Disconnection44:35 Sunlight, Sleep & Circadian Rhythm48:40 Men, Women & Biological Roles53:10 Food, Nutrient Depletion & Seasonality57:45 Sensory Overload & The News1:03:10 Warriors, Nurturers & Purpose1:08:40 Living Like an Animal Again1:12:30 Final Thoughts

Send us a textIn this episode of Never Been Sicker, Michael Rubino interviews healthcare entrepreneur Vivienne Reign about why modern “healthcare” often functions as sick care and why so many people feel worse than ever despite medical advances.Vivienne breaks down the insurance model, the mindset shift required to pursue real wellness, and the difference between proactive biohacking vs reactive medical intervention. They also dive deep into red light therapy, including what makes a device legitimate (wavelength, dose, distance, power, and FDA clearance), how to avoid low-quality products, and how red light can support circulation, inflammation, pain, and neuropathy outcomes.This conversation also covers pelvic floor dysfunction in men and women, why common advice like kegels misses key involuntary muscles, and how improving pelvic floor function can impact sleep quality, incontinence, and long-term quality of life.If you feel like you pay for insurance but still have to figure out your health on your own, this episode will help you rethink the system and take back control.

Dr. Josh shares how he reversed obesity and hypertension, then lays out the top 10 lifestyle strategies to make aging optional. #Longevity #HealthTransformation #AntiAging #HealthTalks

Your butt is not about aesthetics. It is a longevity organ that directly impacts metabolism, brain optimization, resilience, and how long you stay strong as you age. In this episode, you'll learn why strength training and protein intake matter more than body fat percentage, how mitochondria drive human performance and recovery, and why building muscle protects your brain, stabilizes mood, and supports long-term longevity. This conversation reframes biohacking, anti-aging, and health from weight loss to muscle span, the length of time you live with strong, functional skeletal muscle. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Gabrielle Lyon, an accomplished physician and New York Times bestselling author of Forever Strong: A New, Science-Based Strategy for Aging Well, and author of the upcoming The Forever Strong Playbook, releasing January 27, 2026. Dr. Lyon pioneered the Muscle-Centric Medicine® approach, which places muscle at the center of disease prevention, metabolic health, and true vitality. She has trained elite athletes, military operatives, and public figures, while also living this philosophy at home as a mother of two with her husband, a retired Navy SEAL. Together, they break down why intermuscular fat may matter more than body fat percentage, how skeletal muscle drives insulin sensitivity and lowers inflammation, and why becoming physically stronger improves brain function and neuroplasticity. They explore protein needs across the lifespan, fasting, ketosis, carnivore-style nutrition, supplements, sleep optimization, and the real tradeoffs of GLP-1 drugs, including the risk of accelerated muscle loss if strength and protein are neglected. The conversation also covers mindset, hormesis, and why physical resilience creates emotional regulation and clearer decision-making in a world increasingly shaped by AI and convenience. This episode is essential listening for anyone serious about biohacking, hacking human performance, longevity, mitochondria, neuroplasticity, nootropics, metabolism, functional medicine, anti-aging strategies, supplements, and living Smarter Not Harder, ideally with a cup of Danger Coffee in hand. You'll Learn: • Why your glutes and skeletal muscle are critical drivers of longevity and brain health • Why intermuscular fat can matter more than body fat percentage for metabolic dysfunction • How strength training improves neuroplasticity, cognition, and emotional resilience • Why protein needs increase with age and why outdated limits can hold you back • What GLP-1 drugs get right, where they fail, and how to protect muscle span • Why progressive stimulus beats lifting heavy for long-term strength and injury prevention • How sleep optimization and recovery support mitochondria and human performance • How building muscle creates clarity, resilience, and better decision-making Dave Asprey is a four time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Thank you to our sponsors! Quantum Upgrade | Support your brain, energy, focus, sleep, and recovery with Quantum Upgrade, a 24/7 streaming quantum energy service designed to work continuously in the background. Try it free for 15 days with no credit card required: https://quantumupgrade.io/DAVE Screenfit | Get your at-home eye training program for 40% off using code DAVE at https://www.screenfit.com/dave BrainTap | Go to http://braintap.com/dave to get $100 off the BrainTap Power Bundle. KillSwitch | If you're ready for the best sleep of your life, order now at https://www.switchsupplements.com and use code DAVE for 20% off. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: muscle longevity organ, glutes brain health, strength training longevity podcast, muscle span aging, intermuscular fat metabolism, IMAT insulin resistance, skeletal muscle brain function, neuroplasticity strength training, protein intake aging, high protein diet longevity, metabolism muscle health, mitochondria muscle brain, muscle centric medicine podcast, gabrielle lyon podcast, forever strong playbook, women strength training longevity, GLP-1 muscle loss, sarcopenia aging prevention, resistance training brain health, sleep optimization muscle recovery, fasting ketosis muscle health, carnivore diet muscle metabolism, functional medicine muscle health, biohacking strength longevity, human performance muscle, anti-aging strength training, supplements muscle recovery, progressive stimulus training, blood flow restriction training, muscle resilience mindset Resources: • Get Gabrielle's NEW book Forever Strong: https://drgabriellelyon.com/forever-strong/ • Gabrielle's Website: https://drgabriellelyon.com/ • Follow Gabrielle's Instagram: https://www.instagram.com/drgabriellelyon/ • Gabrielles Youtube: https://www.youtube.com/@DrGabrielleLyon • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Join My Low-Oxalate 30-Day Challenge: https://daveasprey.com/2026-low-ox-reset/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com Timestamps: 0:00 – Introduction 1:01 – The Playbook vs Workbook 3:47 – Protein & Metabolic Health 6:21 – Mindset & Negativity 7:20 – Histamines & Hot Flashes 10:49 – Women & Strength Training 13:40 – Connective Tissue & EDS 16:15 – Muscle Span & Aging 19:41 – Training for Kids 21:55 – Pain Cave & Discomfort 25:25 – Emotional Regulation 29:46 – Resilience & Dating 32:11 – Building Friction & Discernment 35:47 – Self-Denial vs Awareness 41:03 – Mitochondria & Energy 42:46 – Bigger Booty, Bigger Brain 44:52 – Body Fat vs IMAT 49:01 – Measuring Muscle Health 52:08 – GLP-1s & Muscle Loss 56:12 – Protein Absorption Myths 59:30 – mTOR & Protein 1:01:29 – Closing Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Modern women are doing the most—tracking, supplementing, optimizing—yet still feel tired, inflamed, and strangely off. And sometimes the issue isn't another protocol. It's the life you're living. Queen Oluwatobiloba explores women's holistic wellness through a lens we don't talk about enough: alignment. We unpack how your environment can mirror your internal season, why "being stuck" drains your vitality, and how discomfort is often the clearest sign you're choosing something true. We also go into motherhood as an initiation (and why mom guilt is so biologically sticky), plus the missing longevity conversation: no supplement can override the relationship, job, or lifestyle that keeps your nervous system in survival mode.  WE TALK ABOUT:  07:40 - Womb power as the courage muscle for radical change  12:45 - Differentiating sensing from feeling for clearer decisions  14:00 - Nature archetypes as a map for energy, boundaries, and burnout risk  19:35 - Motherhood revealing your true nature and unmet support needs  22:20 - Sacrifice, support, and why moms hit depletion so fast  26:35 - Releasing guilt and shame as a hormonal + energetic reset  29:40 - Womb connection practice to identify what you're carrying  38:30 - When "fixing the symptom" hides unresolved root patterns  40:45 - Longevity through value alignment and living by your blueprint  45:00 - Why biohacking can't override a misaligned life  53:55 - Choosing discomfort now to protect vitality later SPONSORS: Join me in Costa Rica for Optimize Her, a 5-night luxury women's retreat in Costa Rica with yoga, healing rituals, and biohacking workshops—only 12 spots available. RESOURCES: Join my free live 2-day masterclass on intuition, nervous system regulation, and feminine rhythms to build sustainable energy, balance hormones, and support long-term vitality. Live January 21 & 22 at 12PM CST (replay included). Download the non-toxic baby registry guide to reduce toxic exposure and make confident, evidence-informed choices for your family—free. Explore my luxury retreats designed to restore your nervous system, optimize health, and support true longevity. Join my NEW private community at TheLongHerLife.com for ongoing protocols, live coaching, and deeper support. Queen Oluwatobiloba's website and Instagram LET'S CONNECT: Instagram, TikTok, Facebook Shop my favorite health products Listen on Spotify, Apple Podcasts, YouTube Music

How do you master the psychology of performing under pressure without falling apart? For over 25 years, Dr. Michael Gervais has worked with elite athletes and high performers who look unstoppable on paper, yet crack when the stakes are highest. Through decades of research and coaching, he's uncovered what separates those who rise in high-pressure moments from those who spiral. In this episode, Michael breaks down the mental skills top performers use to stay calm, focused, and creative under pressure, and how entrepreneurs can apply the same frameworks to protect their mental health and perform at their best. In this episode, Hala and Dr. Michael will discuss: (00:00) Introduction (03:13) Mastery of Self in an AI World (06:47) Why Entrepreneurs Need Mental Training (10:25) Practical Ways to Train Your Mind Daily (18:20) Mastering Breath Work and Mental Imagery (27:40) The Psychology of High-Pressure Performance (38:11) Goal Setting Without Fear of Opinions (47:35) Managing Emotions in Leadership (54:56) Building Psychological Safety Within a Team (1:00:10) How to Truly Understand Your Team Dr. Michael Gervais is a high-performance psychologist, bestselling author, and host of the Finding Mastery podcast. He has worked with world record holders, Olympians, internationally acclaimed artists and musicians, MVPs from every major sport, and Fortune 100 CEOs to optimize mindset and performance. Dr. Michael is widely known for his work on mastery of self, emotional regulation, and thriving under pressure. Sponsored By: Indeed - Get a $75 sponsored job credit to boost your job's visibility at Indeed.com/profiting  Shopify - Start your $1/month trial at Shopify.com/profiting.  Spectrum Business - Visit Spectrum.com/FreeForLife to learn how you can get Business Internet Free Forever. Northwest Registered Agent - Build your brand and get your complete business identity in just 10 clicks and 10 minutes at northwestregisteredagent.com/paidyap Framer - Publish beautiful and production-ready websites. Go to Framer.com/profiting and get 30% off their Framer Pro annual plan. Intuit QuickBooks - Start the new year strong and take control of your cash flow at QuickBooks.com/money  Quo - Run your business communications the smart way. Try Quo for free, plus get 20% off your first 6 months when you go to quo.com/profiting   Working Genius - Take the Working Genius assessment and discover your natural gifts and thrive at work. Go to workinggenius.com and get 20% off with code PROFITING Resources Mentioned: Michael's Podcast, Finding Mastery: bit.ly/F-Mastery  Michael's Book, The First Rule of Mastery: bit.ly/TFROM  Michael's Website: findingmastery.com Michael's Instagram: instagram.com/michaelgervais  Michael's LinkedIn: linkedin.com/in/drmichaelgervais  YAP E287 with Dr. Michael Gervais: youngandprofiting.co/TRBYMAPE287  Active Deals - youngandprofiting.com/deals  Key YAP Links Reviews - ratethispodcast.com/yap YouTube - youtube.com/c/YoungandProfiting Newsletter - youngandprofiting.co/newsletter  LinkedIn - linkedin.com/in/htaha/ Instagram - instagram.com/yapwithhala/ Social + Podcast Services: yapmedia.com Transcripts - youngandprofiting.com/episodes-new  Entrepreneurship, Entrepreneurship Podcast, Business, Business Podcast, Self Improvement, Self-Improvement, Personal Development, Starting a Business, Strategy, Investing, Sales, Selling, Psychology, Productivity, Entrepreneurs, AI, Artificial Intelligence, Technology, Marketing, Negotiation, Money, Finance, Side Hustle, Startup, Mental Health, Career, Leadership, Mindset, Health, Growth Mindset, Wellness, Biohacking, Motivation, Manifestation, Brain Health, Life Balance, Self-Healing, Positivity, Happiness, Sleep, Diet

I'm excited to share my conversation with Julie Olson, who developed her game-changing HealthyHairFix protocol after experiencing severe hair loss herself. Julie breaks down her 5-R framework that addresses 76 different causes of hair loss through five functional categories. We dive into the surprising gut-hair connection, why biotin supplements might be working against you, and how hidden toxins like mercury fillings trigger hair loss. You'll discover why topical treatments can't fix internal problems and learn the lifestyle secrets Julie observed in Sardinia's blue zone. If you're dealing with hair loss, this episode offers hope and a clear roadmap for addressing root causes instead of just masking symptoms. For the complete show notes, links and transcripts, visit inspiredliving.show/228

Your gut already has its own version of Ozempic, and it's been doing this job long before injections existed.In this video, I explain how appetite is actually regulated, why synthetic shortcuts often create new problems over time, and what has quietly shut down the body's natural satiety signals for so many people.Once you understand the pathway drugs are trying to imitate, the question stops being “how do I eat less?” and becomes “why was my body blocked from doing this in the first place?”This is about restoring a system, not overpowering it.Chapters0:00 - Introduction: Your Body's Natural Ozempic0:53 - Hunger Is a Hormone Problem5:08 - How to Fix Your Hormone Signals7:28 - Why Ozempic Often Backfires10:54 - The Resistant Starch Solution15:03 - How to Use Resistant Starch18:12 - Rebuilding Your Gut Environment19:31 - Lifestyle Support for Gut HealthResources: • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Connect with Dave Asprey!Website: https://daveasprey.comTikTok: https://www.tiktok.com/@daveaspreyofficialInstagram: https://www.instagram.com/dave.asprey/Facebook: https://www.facebook.com/Daveaspreyofficial/X: https://x.com/daveaspreyYouTube: https://www.youtube.com/c/daveaspreybprThe Human Upgrade Podcast: Instagram: https://www.instagram.com/TheHumanUpgradePodcast/ Facebook: https://m.facebook.com/Thehumanupgrade/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode of the BiohackingVille podcast, host Rob Rene introduces himself and sets the stage for his mission to uncover truths in health and wellness outside the conventional medical system. Born in Pocatello, Idaho, Rene's life has been shaped by a combination of athletic achievements, a spiritual journey, and personal health crises that have redefined his path. From being a dedicated runner to battling both addiction and cancer, he recounts how these experiences transformed him into a faith-based wellness advocate. Rene discusses his research into holistic health, the impact of AI, and the corrupt practices of Big Pharma. He introduces his unique strategy for combining faith, biohacking, and wellness technologies to help others reclaim their health. He also outlines the first three episodes of his podcast series, which will delve deeper into integrating faith and biohacking, practical wellness strategies, and the new solutions he's developing to support health and wellness.00:00 Introduction and Disclaimer01:15 Welcome to Biohacking Ville01:26 The Genesis Arc: Rob's Mission04:17 Rob's Early Life and Athletic Journey12:36 The First Truck: Life-Changing Accident17:40 The Second Truck: Pandemic and Awakening20:29 Research and Realizations27:00 Discovering Quantum Energy28:02 Understanding Frequencies and Human Body29:34 Creating Health Solutions30:42 The Journey with Molecular Hydrogen35:09 A Life-Saving Cancer Diagnosis41:10 Launching BiohackingVille46:56 The Vision for Biohacking V

In this episode of the BiohackingVille Podcast, host Rob Rene interviews Dr Porcello from Tijuana about the transformative healthcare offered at their facility which combines holistic dental and integrative oncology treatments. Dr. Portilla shares his journey into the medical field, discusses the founding and growth of their clinic, and delves into the benefits of holistic dentistry, particularly the removal of mercury fillings and the treatment of root canals and cavitations. The conversation also covers their integrative approach to cancer treatment, combining therapies like hyperthermia, dendritic cells, and low-dose chemotherapy to improve patient outcomes. Testimonials and personal anecdotes highlight the effectiveness of these treatments, making a compelling case for medical tourism to Tijuana for holistic and integrative healthcare solutions.TakeawaysThe clinic has been evolving for 26 years, starting as a dental clinic.Holistic dentistry focuses on biocompatible materials and patient health.Integrative oncology combines conventional and alternative treatments.Dental health can significantly impact overall health and cancer outcomes.Mercury fillings are toxic and should be removed carefully.Root canals can lead to long-term health issues if not managed properly.The clinic offers a range of services including IV therapies and regenerative medicine.Success stories highlight the effectiveness of integrative approaches to cancer treatment.Dendritic cell therapy is a promising treatment for cancer.Tijuana is a safe and effective destination for medical tourism.

This episode covers: • Real Food Reset in U.S. Dietary Policy The new Dietary Guidelines for Americans 2025–2030 put real food back at the center of U.S. nutrition policy and take a direct swing at ultra processed foods, added sugar, and sugary drinks. Dave breaks down why this matters beyond personal dieting: these guidelines influence school meals, SNAP and WIC, federal feeding programs, and they shape what eventually shows up on labels and in public institutions. He also shares how biohackers can use this shift as leverage to push for better food environments in schools, workplaces, and hospitals. -Source: https://www.usda.gov/about-usda/news/press-releases/2026/01/07/kennedy-rollins-unveil-historic-reset-us-nutrition-policy-put-real-food-back-center-health • Drug Combo Extends Lifespan of Frail Old Mice by 73% A new aging study found that combining oxytocin with a compound called A5i extended the remaining lifespan of frail elderly male mice by 73%, while also improving function and tissue health. Dave explains why this is a big signal for the future of longevity medicine: stacking targeted interventions can outperform single compounds, especially when you start late in life. He also explains what to do with the idea right now: stop building random “everything stacks” and start thinking in phases, tracking outcomes, and waiting for real human combo data. -Source: https://www.futura-sciences.com/en/study-finds-drug-combo-could-slow-aging-and-increase-lifespan-by-73_23229/ • ChatGPT Health Turns Your Data Into a Health OS OpenAI launched ChatGPT Health, a dedicated health experience that lets you securely connect medical records and wellness apps like Apple Health and MyFitnessPal, so you can summarize visits, interpret labs, and prepare better questions for your doctor. Dave explains why this is a turning point for quantified self and protocol building: it reduces the friction of pulling data from five different places, and it makes pattern-finding accessible to nontechnical people. He also shares how to use it like a pro: clean inputs, smarter questions, and better doctor conversations. -Source: https://openai.com/index/introducing-chatgpt-health/ • Whole Milk Is Back in Schools The Whole Milk for Healthy Kids Act restores whole and reduced-fat milk options in schools, aligning school nutrition rules with the updated dietary guidelines that no longer treat full-fat dairy like a default villain. Dave breaks down why this matters for child healthspan: satiety and nutrient density drive behavior, learning, and metabolic stability. He also explains why this is a real-world policy experiment worth watching across school districts, and how it can open the door for bigger institutional upgrades like better protein and fewer ultra processed items. -Source: https://www.usda.gov/about-usda/news/press-releases/2026/01/14/whole-milk-back-president-trump-signs-whole-milk-healthy-kids-act • Tirzepatide Trial Targets Biological Age With Aging Clocks A registered clinical trial titled Tirzepatide to Slow Biological Aging is using multiple DNA methylation aging clocks as primary endpoints, along with functional metrics like grip strength and a 6-minute walk test. Dave explains why this is a big maturity step for longevity science: instead of assuming metabolic improvement equals slower aging, this study is measuring biological age directly, across multiple clocks, with performance outcomes. He also shares the practical lesson for biohackers: stop relying on one favorite metric and start thinking in panels, function, and durability of results. -Source: https://clinicaltrials.gov/study/NCT07220473 All source links provided for direct access to the original research and reporting. This episode is designed for biohackers, longevity seekers, and high-performance listeners who want practical strategies rooted in cutting-edge science. Host Dave Asprey translates emerging research into actionable upgrades for your biology, from metabolism and food policy to AI-driven tracking, institutional nutrition, and biological aging measurement. New episodes every Tuesday, Thursday, Friday, and Sunday. Keywords: Dietary Guidelines for Americans 2025-2030, real food policy reset, ultra processed foods policy, added sugar limits, sugary drinks guidelines, school lunch nutrition policy, SNAP WIC nutrition impact, USDA HHS dietary guidelines 2026, whole food protein guidelines, full fat dairy guidelines, oxytocin aging study, A5i lifespan extension, frail elderly mice lifespan 73 percent, combination longevity therapies, aging intervention synergy, staged longevity protocols, functional aging biomarkers, ChatGPT Health launch, OpenAI health records AI, Apple Health ChatGPT integration, MyFitnessPal ChatGPT integration, AI lab interpretation, AI doctor visit summary, quantified self AI tools, Whole Milk for Healthy Kids Act, whole milk back in schools, school dairy policy change, child satiety nutrition, school meal regulations USDA, tirzepatide biological aging trial, GLP-1 GIP longevity, epigenetic aging clocks trial, DNAmAge PhenoAge GrimAge DunedinPACE, grip strength aging endpoint, 6 minute walk aging endpoint, biological age measurement, longevity clinical trial endpoints, biohacking news update, longevity policy shifts, metabolic health upgrades Thank you to our sponsors! -BEYOND Conference 2026 | Register now at https://beyondconference.com/ -EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE for 40% off Resources: • Subscribe to my weekly newsletter: https://substack.daveasprey.com/welcome • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps:0:00 - Intro0:19 - New Dietary Guidelines2:09 - Longevity Research Breakthrough3:41 - ChatGPT Health Launch5:10 - Whole Milk Returns to Schools6:29 - GLP-1 Aging Trial7:34 - Weekly Upgrade Protocol9:09 - OutroSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today, I'm joined by the incredible Anthony Castore, a trailblazer who fuses elite strength coaching with deep cellular medicine. In our conversation, Anthony shares his journey from a young athlete determined to defy genetic odds to becoming an expert in both physical training and the nuanced science of peptides, mitochondria, and bioregulators.   Use code NAT10 for 10% off products at https://alchemiqlabs.com/   Episode Timestamps: Welcome and episode introduction ... 00:00:00 Anthony Castore's path from strength coaching to cellular medicine ... 00:05:55 Connecting strength training with cellular pathways (AMPK, mTOR) ... 00:12:27 Explaining and balancing AMPK and mTOR for performance ... 00:13:03 Training strategies: Metabolic, hypertrophy, and neural approaches ... 00:18:18 Building a solid foundation: Lifestyle, training, nutrition, peptides ... 00:23:04 Assessing recovery capacity and individualizing protocols ... 00:26:02 Mitochondrial fission, fusion, and targeted adaptation ... 00:29:57 Optimizing muscle gain and fat loss through calories and recovery ... 00:31:00 Differentiating bodybuilder vs. longevity approaches ... 00:34:44 Integrating peptides and support molecules into routines ... 00:40:44 Ketone esters and mitochondrial peptide interventions ... 00:41:20 Cautions on stacking and combining interventions ... 00:54:04 Lessons learned from overdoing interventions ... 01:05:02   Our Amazing Sponsors: Vitali - combines pharmaceutical-grade copper peptides with zero-age exosomes to support clearer cellular signaling and long-term skin resilience, working with your biology instead of forcing change. Visit VitaliSkincare.com and use code NAT20 for 20% off.   BEAM Minerals - Low energy often starts in the mitochondria. Support cellular energy with a bioavailable liquid mineral supplement — and get 20% off at beamminerals.com with code NAT20.   Complete Liver Complex by LVLUP Health - supports your liver's natural detox pathways so your body can reset after the holidays without suffering. Go to lvluphealth.com and use code NAT for 20% off.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

Get Fitness Lab (20% off for listeners), the #1 coaching app that adapts to YOUR recovery, YOUR schedule, and YOUR body. Build muscle, lose fat, and get stronger with daily personalized guidance. Now with Apple Health integration.--Are biohacks keeping you stuck instead of helping you lose fat and build muscle? Why does body recomp feel so hard even when you are doing all the “right” things?Body recomp, build muscle, and lose fat come up constantly on fitness podcasts, but I keep seeing the same mistake. People chase cold plunges, red light therapy, peptides, and supplements while ignoring the basics of nutrition and fitness. I sat down with Jenn Trepeck, author of Uncomplicating Wellness and host of Salad with a Side of Fries, to flip that script.We break down her concept of biostacking and why most people are operating at 50 to 60 percent capacity. We talk protein, fiber, hydration, sleep, stress, connection, and why metabolism only improves when the basics are in place. This conversation ties directly into Wits and Weights, evidence-based fitness, and evidence-based nutrition for sustainable weight loss, strength training, and long-term health.Today, you'll learn all about:0:00 – Why biohacks fail most people3:00 – Biohacking vs biostacking explained6:00 – Metabolic health reality check9:30 – Building a real foundation13:30 – Nutrition basics that matter18:00 – Movement and muscle building24:00 – Stress, sleep, and recovery31:00 – Connection and longevity38:00 – Where to start practicallyEpisode resources:Jenn's Book: Uncomplicating Wellness: Ditch the Rules. Quiet the Noise. Reclaim Your Life.Website: asaladwithasideoffries.comPodcast: Salad With a Side of FriesFacebook: @Saladwithasideoffriespodcast Instagram: @saladwithasideoffriespodYouTube: @jenntrepeck Support the show

In this engaging episode of BiohackingVille, host Rob Rene delves into the fascinating world of frequencies and their transformative impact on health. He shares personal experiences and scientific research, including Stanford and IBM studies, to uncover how frequencies can aid healing. Rob introduces the concept of using crystalline structures to store and transmit frequencies, along with practical applications like frequency devices and patches. The episode also explores Dr. Emoto's experiments on water crystals, emphasizing the significant effects of positive and negative intentions. Listeners are invited to become their own health advocates by integrating holistic and biohacking approaches into their wellness journey. Subscribe to stay updated on innovative health strategies and inspiring guest interviews.00:00 Introduction and Disclaimer00:27 Welcome to Biohacking with Rob Rene01:16 Exploring the Power of Frequencies02:47 Stanford's Hidden Research on Frequencies04:08 Personal Stories of Transformation06:39 The Science Behind Frequencies and Healing10:19 Practical Applications of Frequency Devices14:54 Understanding the Human Body's Energy Field21:16 Real-World Examples and Studies24:32 Exploring Frequency Devices25:45 Dr. Emoto's Water Experiments28:43 Impact of Intentions on Water and Body32:42 Transformative Stories of Healing34:52 Introduction to Biohacking VI35:51 Integrative Oncology and Personal Journey39:31 Holistic Health and Future Plans42:54 Combining Frequencies and Red Light Therapy44:51 Launching Biohacking Ville47:23 Final Thoughts and Call to Action

In this Episode of BiohackingVille, host Rob Rene introduces Dr. Tracy Stroup, a naturopathic doctor and chief health officer at Get Healthy Store, who shares her journey from personal training to natural health and biohacking. The discussion covers Dr. Stroup's new initiative, Quarterbacking Cancer, inspired by her friend's breast cancer misdiagnosis. She details navigating conventional and integrative oncology, emphasizing patient-centered care and education. The episode also highlights the Anti Appleseed Project, an annual integrative oncology event. Dr. Stroup discusses the importance of the mind-body-spirit connection, patient advocacy, and practical advice on supporting the body's natural healing processes over a two-year regeneration period. 00:00 Introduction to Biohacking and Healing 00:48 Meet Dr. Tracy Stroup 01:24 Dr. Tracy's Journey and Expertise 02:52 Quarterbacking Cancer: A New Approach 04:59 Integrative Oncology and the Anti Appleseed Project 10:47 Personal Cancer Journeys and Insights 13:02 Strategic Healing and Personalized Care 24:25 Embracing the Battle Within 25:12 The Football Team Analogy 27:24 Healing Through Motivation and Faith 30:14 The Power of Patience and Peace 34:25 The Two-Year Transformation Plan 37:17 Mind, Body, and Spirit Connection 38:33 Quarterbacking Cancer and Final Thoughts

Most brain decline, mood instability, and impulsive behavior start with a breakdown in how the brain's immune cells produce and use energy. This episode shows how mitochondrial health inside microglia influences cognition, emotion, and long-term brain resilience, and how everyday inputs quietly push those systems toward damage or repair. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey is joined by Dr. David Perlmutter, a board-certified neurologist and six-time New York Times bestselling author whose work focuses on the intersection of neurology, nutrition, metabolism, and brain health. A Fellow of the American College of Nutrition and member of the Editorial Board of the Journal of Alzheimer's Disease, Dr. Perlmutter brings decades of clinical and research experience to this conversation on how inflammation and mitochondrial function shape the brain across the lifespan. Together, they explore how microglial cells shift their behavior based on metabolic conditions, and how those shifts influence neurodegeneration, emotional regulation, impulse control, and cognitive performance. The discussion covers real-world inputs that shape these systems, including sleep optimization, fasting, ketosis, glucose regulation, gut signaling, environmental toxins, and tools referenced in the episode such as red and infrared light, 40 Hz light and sound, hyperbaric oxygen, lithium, nicotine, supplements, nootropics, GLP-1 agonists, and dietary approaches like carnivore and ketosis. The conversation connects brain biology to lived experience, showing how metabolism influences behavior, decision making, and long-term human performance through a Smarter Not Harder lens. You'll Learn: • How microglia shift between supportive and destructive states and why metabolism drives that change • How mitochondrial function inside immune cells influences inflammation and brain resilience • How inflammation affects the prefrontal cortex, impulse control, and reward-driven behavior • What the episode says about GLP-1 agonists and behavior changes like reduced cravings and gambling • How gut-derived signaling and short-chain fatty acid balance (butyrate vs propionate) relates to brain function • How tools like red and infrared light, hyperbaric oxygen, and 40 Hz light and sound connect to microglia • The lifestyle levers discussed in the episode: sleep optimization, fasting, ketosis, glucose control, and toxin reduction • The compounds mentioned, including lithium, nicotine, urolithin A, CoQ10, rosmarinic acid, and dihydromyricetin Dave Asprey is a four time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Thank you to our sponsors! KILLSwitch | If you're ready for the best sleep of your life, order now at https://www.switchsupplements.com/ and use code DAVE for 20% off. BodyGuardz | Visit https://www.bodyguardz.com/ and use code DAVE for 25% off. Stop cooking with toxic cookware and upgrade to Our Place today. With a 100-day risk-free trial, plus free shipping and returns, you can experience this game-changing cookware with zero risk. Visit: fromourplace.com/DAVE Use code: DAVE for 10% off sitewide Establish a powerful foundation for sustained wellness with Pique. Unlock 20% off: piquelife.com/DAVE Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: microglia brain health, brain immune system mitochondria, neuroinflammation podcast, mitochondrial dysfunction brain, david perlmutter podcast, dr david perlmutterneurologist, grain brain author podcast, alzheimers brain metabolism, parkinsons microglia, autism brain inflammation, gut brain immune signaling, short chain fatty acids brain, butyrate propionate brain, glp-1 brain behavior, glp-1 addiction research, red light therapy brain, infrared light mitochondria brain, 40 hz light sound brain, hyperbaric oxygen brain health, lithium microglia brain Resources: • Learn More About Dr. Perlmutter at: https://drperlmutter.com/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Join My Low-Oxalate 30-Day Challenge: https://daveasprey.com/2026-low-ox-reset/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com Timestamps: 0:00 - Introduction 1:45 - Autism Spectrum 4:38 - Alzheimer's & Beta Amyloid 7:02 - Brain Immune Cells 8:06 - GLP-1 & Parkinson's 10:44 - M1 vs M2 Microglia 13:08 - Pharmaceutical Microdosing 15:51 - Gene Therapy 19:09 - Mold & Toxins 21:58 - Environmental Pollution 26:05 - MPTP Discovery 29:07 - Healing Interventions 31:39 - Light & Sound Therapy 36:35 - Mitochondrial Function 44:57 - Inflammation & Prefrontal Cortex 48:00 - GLP-1 Global Impact 52:11 - Mitochondrial Community 56:05 - Consciousness & The Field 1:00:00 - Psychedelics 1:01:59 - Love & Judgment 1:06:35 - Death & Knowing 1:09:06 - Heart-Brain Connection 1:11:06 - Closing Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Join tech veteran turned neurotherapist James Croall (Peakmind.health), Jay Gunkelman QEEGD (500,000+ brain scans), Dr. Mari Swingle (i-Minds author), and host Pete Jansons for a deep dive into:

Ever wonder which health trends are actually worth your time in 2026? Nick Urban breaks down what truly moves the needle… active wearables, multi-sensor monitoring, recovery systems, & environment-first strategies that deliver measurable ROI. Meet our host Nick Urban is a BioHarmonizer, athlete, and founder of Outliyr.com, as well as the host of theHigh Performance Longevity podcast. A certified Chek Practitioner, Personal Trainer, and Performance Health Coach, he bridges the gap between ancient medical systems like Ayurveda & Traditional Chinese Medicine and cutting-edge modern science. Nick is dedicated to distilling the wisdom of the world's top performers into practical strategies, helping others transition from merely surviving to truly thriving. Thank you to our partners Outliyr Biohacker's Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Ultimate Health Optimization Deals: a roundup article of all the best current deals on technology, supplements, systems and more Gain mental clarity, energy, motivation, and focus with the FREE Outliyr Nootropics Mini-Course The simple, guided, and actionable Outliyr Longevity Challenge helps you unlock your longevity potential, slow biological aging, and maximize your healthspan Key takeaways Devices now regulate your biology instead of only tracking it, saving time & guesswork Clean water & clean air outperform fancy diets, boosting recovery, sleep, & energy Digital twins let you test health changes virtually, predicting long term results with real data Multi sensor wearables track more than glucose, showing hormones & biomarkers together for better decisions Mental training matters as much as physical training, with practices like meditation becoming mainstream for resilience & focus Next generation light panels mimic sunlight using multiple wavelengths, delivering broader benefits than narrow spectrum devices Peptides now come as sprays, strips, & capsules instead of only injections, improving ease of use & safety Regulations increasingly target ultra processed addictive foods, pushing better metabolic health & clearer labels Recovery practices like hot cold therapy, breathwork, & saunas are becoming social rituals that blend health & community Women's health research & technology are expanding, delivering more tailored & effective solutions Episode highlights 0:00 Introduction 01:23Track health trends with systems thinking 02:29 Move from passive wearables to active regulation 05:39 Optimize foundational inputs like water & air 09:17 Personalize health with multi sensor intelligence 12:32 Train mental fitness & nervous system resilience 21:02 Redefine recovery longevity & future health Links Watch it on YouTube: https://youtu.be/S4QSzlMJmI4  Full episode show notes: outliyr.com/245 Connect with Nick on social media Instagram Twitter YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick

In this inaugural episode of the Biohacking Ville podcast hosted by Rob Rene, Dr. Chris is the special guest. The discussion covers a wide range of topics related to holistic health, biohacking, and integrative medicine. Dr. Chris, an osteopathic doctor with years of experience in both conventional and holistic treatment methods, shares his journey and insights into alternative healing strategies, such as peptides, exosomes, stem cells, and IV therapy. The episode emphasizes the importance of a positive mindset, preparatory methods for treatment, and the role of God in health and healing. Additionally, they discuss the concept of the Wellness and Healing Place for Exceptional People (WAPE) Collective, a private membership association focused on holistic health services. This episode sets the groundwork for the podcast's mission to empower individuals to take control of their health journey.00:00 Introduction and Disclaimer01:14 Welcome to Biohacking Vil Podcast01:54 Introducing Dr. Chris04:59 Dr. Chris's Medical Journey07:44 Holistic Health and WP Collective14:32 Peptides and Regenerative Medicine26:05 Medical Tourism and Stem Cell Treatments27:04 Regulations on Peptides and Stem Cells27:51 The Rise of IV Treatments29:09 Popular IV Treatments and Their Benefits31:02 Understanding NAD and Its Role in Health32:06 Private Membership Associations Explained34:09 The Importance of Holistic Health Coaching43:11 Mind-Body Connection and Positive Thinking48:28 Conclusion and Contact Information

In dieser spannenden Podcast-Folge geht es um ein Ziel, das gleichzeitig absurd und doch ziemlich vernünftig ist: gesund sterben. Also nicht möglichst lange irgendwie durchhalten, sondern möglichst lange fit, klar und belastbar bleiben. Mein Gast Georgiy Michailov schaut darauf, was wirklich wirkt und was einfach nur gut klingt. Wir sprechen über Studien, Ernährungsweisen, Routinen und die großen Klassiker: Krafttraining, Ernährung, Schlaf. Georgiy ist Managing Partner bei SMP (Struktur Management Partner) und begleitet Unternehmen in Restrukturierung und Transformation. Turnaround ist sein Beruf. Und genau deshalb ist dieses Gespräch so interessant: Weil wir immer wieder bei derselben Logik landen, die für Körper und Unternehmen gilt. Wir können unseren Einsatz und die Prozesse beeinflussen, aber nicht das Ergebnis. Dieser Gedanke stammt aus dem Stoizismus und kann in Veränderungsprozessen jeglicher Art den Unterschied machen. Ein Gespräch über Gesundheit ohne Hype, über Evidenz statt Bauchgefühl und über die Kraft der Selbstverantwortung. Im Gespräch geht es unter anderem um: - Longevity: Was wirklich zählt und was überschätzt wird - Ernährung: Muster, Studien, Denkfehler und praktische Konsequenzen - Krafttraining als Versicherung fürs Alter - Stoizismus: Fokus auf Einsatz statt Ergebnis - Turnarounds: Was es auf Werteebene braucht, damit Transformation gelingt Über Georgiy Michailov: Georgiy Michailov ist Managing Partner bei Struktur Management Partner, einer auf Transformations- und Turnaround-Management im gehobenen Mittelstand spezialisierten Unternehmensberatung. Das Werteverständnis und die Aufgaben faszinierten ihn seit seinem Einstieg als Praktikant im Jahr 2003. Er durchlief alle Entwicklungsstufen und wurde 2009 Partner sowie 2013 Managing Partner. Heute verantwortet er strategisches Marketing, Vertrieb und Methodenentwicklung. Hier geht's zu seinem ausführlichen Profil: https://www.georgiy-michailov.de/ Als Co-Autor hat Georgiy Michailov mehrere Bücher geschrieben, unter anderem: „Geschäftsmodell-Redesign: Dimensionen bewerten, Werthebel identifizieren, Transformation gestalten – Ein Praxisbuch“ Alle Informationen zum Buch findet ihr hier: https://www.geschaeftsmodell-redesign.de/ Außerdem hostet er den Management-Podcast SMP LeaderTalks: https://www.struktur-management-partner.com/insights/leadertalks Alle Informationen zu meiner Arbeit findet ihr wie immer unter: www.hannah-panidis.de Und hier begegnet ihr mir meist tagesaktuell: Instagram: https://www.instagram.com/hannahpanidis LinkedIn: https://www.linkedin.com/in/hannah-panidis-55141a145/?originalSubdomain=de Facebook: https://www.facebook.com/HannahPanidisKommunikation/?locale=de_DE

Drs. Rowan and Kessler introduce ozone and PEMF as powerful, natural therapies for improving oxygenation, immune function, and longevity. #OzoneTherapy #PEMF #HolisticHealing

In this episode of Rational Wellness, Dr. Ben Weitz speaks with Dr. Sanjeev Goel about the science and clinical strategies behind longevity and biohacking. They explore mechanisms of biological aging, key biomarkers that predict lifespan and healthspan, and evidence-based interventions clinicians should consider when addressing aging in their patients. Topics include metabolic health, cellular resilience, testing strategies, and integrative approaches to optimize long-term health.

Send Vanessa a Text MessageFor my listeners, use code VANESSA10 for 10% off any purchase from https://gembared.com/Red light therapy has exploded over the last few years, and with that growth has come a lot of confusion, misinformation, and mixed messages.In this episode, I'm joined again by Andrew LaTour, founder of GembaRed, for an updated, grounded conversation on red light therapy, and what actually matters now in 2026.Andrew first joined me two years ago for a deep-dive episode that became one of the most comprehensive red light therapy guides on the show. This time, we focus on safety, practicality, and clarity in a social-media-driven landscape. We talk about what's changed, what hasn't, where people are getting confused, and how to use red light therapy safely and effectively without overthinking it.This conversation also addresses common listener questions, influencer misuse, misinformation circulating online, and why simple, consistent use often matters more than “perfect” wavelengths or high-intensity devices.In this episode, we cover:What red light therapy (photobiomodulation) actually does at a cellular levelA quick grounding recap for new listenersWhy red and near-infrared light are more flexible than people thinkThe difference between wavelength, intensity, and dosing, and why they're so often confusedWhy higher intensity doesn't automatically mean better resultsHow exposure time impacts mitochondria and ATP productionCommon safety concerns, and where they really come fromThe role influencer culture has played in misinformation and misuseWhether there are any body parts red light should not be used onEye safety, goggles, and why proper use matters more than worryWhy red light therapy is generally very safe when devices are made responsiblyPractical guidance for 10-15 minute sessions and consistencyUsing red light therapy for fertility support and hair lossWhy consumers don't need to obsess over specs to see benefitsConnect with GembaRed and Andrew:GembaRed WebsiteLearn More at GembaRedGembaRed on YouTubeGembaRed on InstagramEmail: gembared@gmail.comConnect with the Podcast:Website: Intentionally Well PodcastSupport the Intentionally Well PodcastPodcast on InstagramVanessa on InstagramPodcast on YouTubePodcast on TikTokPodcast on XEmail: intentionallywellpodcast@gmail.comSupport the showThis episode is for informational purposes only. Please consult a trusted health practitioner for individual concerns.

Your body does not fail all at once. Aging starts when cells quietly shift into survival mode and never come back out. In this episode, you go inside the thinking of a true medical outlier to understand how stress, travel, toxins, and metabolic overload reprogram cells, shut down energy, and accelerate aging, and how restoring mitochondrial function can reverse that trajectory from the inside out. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Dr. Theodore Achacoso and Boomer Anderson, leaders in Health Optimization Medicine and Practice. Dr. Achacoso is a physician-scientist and the founding pioneer of Health Optimization Medicine, known for his work on cellular networks, metabolomics, and mitochondrial function. Boomer Anderson is the CEO of Smarter Not Harder and Troscriptions, where he focuses on translating complex biology into practical tools for human performance and longevity. Together, they unpack how cells respond to perceived threats through the Cell Danger Response, why mitochondria control energy, inflammation, and repair, and why chasing disease labels misses the real drivers of aging. The discussion covers methylene blue as an electron recycler, why LDL cholesterol plays a role in detoxification and immune signaling, how fasting and ketosis shift metabolism between repair and growth, and why sleep optimization, circadian rhythm, and light exposure matter even more when you travel. They also explore neuroplasticity, consciousness, nootropics, supplements, and why health optimization works best when you restore balance instead of forcing outcomes. You'll Learn: • What the Cell Danger Response is and how it reshapes aging and performance • How mitochondria sense stress before symptoms appear • Why cellular energy controls resilience, sleep, and longevity • How methylene blue supports mitochondrial electron flow • Why fasting and ketosis shift metabolism between repair and growth • How travel, light, and circadian disruption affect aging • Why very low LDL can impair detoxification and immune signaling • Why real anti-aging starts at the cellular level, not with disease labels Thank you to our sponsors! AquaTru | Go to https://aquatruwater.com/daveasprey and save $100 on all AquaTru water purifiers. Screenfit | Get your at-home eye training program for 40% off using code DAVE at www.screenfit.com/dave. Puori | Use code DAVE at puori.com/DAVE to get 32% off your Puori Fish Oil when you start a subscription. You save more than $18. fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: cell danger response podcast, mitochondria aging, mitochondrial dysfunction aging, health optimization medicine, dr ted achacoso, boomer anderson, troscriptions, troscriptions methylene blue, methylene blue mitochondria, methylene blue biohacking, cellular aging podcast, anti aging mitochondria, metabolic stress aging, fasting ketosis metabolism, mitochondrial energy production, neuroplasticity mitochondria, sleep optimization aging, functional medicine mitochondria, smarter not harder biohacking, dave asprey mitochondria Resources: • Get A Discount On All Troscription Products with code ‘dave' at: https://troscriptions.com/ • Learn More About Methylene Blue From My Full Masterclass Covering The Topic: https://daveasprey.com/mb/ • Discover More About The ‘Health Optimization Medicine and Practice' From Our Guests: https://homehope.org/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Join My Low-Oxalate 30-Day Challenge: https://daveasprey.com/2026-low-ox-reset/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com Timestamps: 0:00 – Trailer 1:25 – Introduction & Guest Background 3:11 – Health Optimization Medicine Origins 4:26 – Root Causes of Health vs Disease 6:15 – Biohacking & Self-Experimentation 8:19 – Medicinal Plants & Nootropics 11:25 – Travel & Jet Lag Solutions 13:42 – Cell Danger Response 17:38 – Metabolites & Cellular Health 18:57 – LDL & Lipopolysaccharides 20:42 – Cellular Model & First Principles 22:55 – Consciousness & Mitochondria 25:46 – Nanotechnology Research 28:55 – Giving Back & Service 31:17 – Blue Cannatine Development 34:48 – Methylene Blue Products 36:22 – Metformin Discussion 38:00 – Dosing & Cordycepin 41:25 – Closing & Discount Code See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

How does someone run 100-mile weeks for 300 consecutive weeks without destroying their body? Today, I'm with Andrew Glaze to unpack the recovery protocols and biological strategies that make ultra endurance possible. You'll learn actionable insights on recovery, nutrition timing, and what biomarkers actually matter when you're pushing your body to extremes.​​​​​​​​​​​​​​​​ CLICK HERE TO BECOME GARYS VIP!: ⁠https://bit.ly/4ai0Xwg⁠ Connect with Andrew Glaze Website: ⁠https://bit.ly/4jE3QfH⁠  YouTube: ⁠https://bit.ly/4sJopM0⁠  Instagram: ⁠https://bit.ly/49zjkwV⁠  TikTok: ⁠https://bit.ly/4sFjRG8⁠  X.com: ⁠https://bit.ly/49ONldn⁠  LinkedIn: ⁠https://bit.ly/45c3xmm⁠  Pre-sell to his book, "Smile, Or You're Doing it Wrong" Thank you to our partners H2TABS: “ULTIMATE10” FOR 10% OFF: ⁠https://bit.ly/4hMNdgg⁠ BODYHEALTH: “ULTIMATE20” FOR 20% OFF: ⁠http://bit.ly/4e5IjsV⁠ BAJA GOLD: "ULTIMATE10" FOR 10% OFF: ⁠https://bit.ly/3WSBqUa⁠ SNOOZE: LET'S GET TO SLEEP!: ⁠https://bit.ly/4pt1T6V⁠ COLD LIFE: THE ULTIMATE HUMAN PLUNGE: ⁠https://bit.ly/4eULUKp⁠ WHOOP: JOIN AND GET 1 FREE MONTH!: ⁠https://bit.ly/3VQ0nzW⁠ AION: “ULTIMATE10” FOR 10% OFF: ⁠https://bit.ly/4h6KHAD⁠ A-GAME: “ULTIMATE15” FOR 15% OFF: ⁠http://bit.ly/4kek1ij⁠ PEPTUAL: “TUH10” FOR 10% OFF: ⁠https://bit.ly/4mKxgcn⁠ CARAWAY: “ULTIMATE” FOR 10% OFF: ⁠https://bit.ly/3Q1VmkC⁠ HEALF: 10% OFF YOUR ORDER: ⁠https://bit.ly/41HJg6S⁠ RHO NUTRITION: “ULTIMATE15” FOR 15% OFF: ⁠https://bit.ly/44fFza0⁠ GOPUFF: GET YOUR FAVORITE SNACK!: ⁠https://bit.ly/4obIFDC⁠ GENETIC METHYLATION TEST (UK ONLY): ⁠https://bit.ly/48QJJrk⁠ GENETIC TEST (USA ONLY): ⁠⁠https://bit.ly/3Yg1Uk9⁠ Watch  the “Ultimate Human Podcast” every Tuesday & Thursday at 9AM EST: YouTube: ⁠https://bit.ly/3RPQYX8⁠ Podcasts: ⁠https://bit.ly/3RQftU0⁠ Connect with Gary Brecka Instagram: ⁠https://bit.ly/3RPpnFs⁠ TikTok: ⁠https://bit.ly/4coJ8fo⁠ X: ⁠https://bit.ly/3Opc8tf⁠ Facebook: ⁠https://bit.ly/464VA1H⁠ LinkedIn: ⁠https://bit.ly/4hH7Ri2⁠ Website: ⁠https://bit.ly/4eLDbdU⁠ Merch: ⁠https://bit.ly/4aBpOM1⁠ Newsletter: ⁠https://bit.ly/47ejrws⁠ Ask Gary: ⁠https://bit.ly/3PEAJuG⁠ Timestamps 00:00 Intro of Show 02:35 Andrew Glaze's Back Story 04:53 PTSD Recovery for First Responders 10:32 Mental Endurance for Ultra Marathons 15:26 Biohacking and Health Practices 15:59 Andrew's Supplement Routine 23:14 Moab 240 Preparations and Experience 28:28 Hallucinations and Injuries during Distance Racing 49:32 Finishing the Moab 240 Race 50:44 Balancing Running and Firefighting 54:15 Motivation in Running Marathons 1:13:37 Goal-Setting and Accomplishments 1:01:29 Prioritising Health Today 1:04:19 Recovery Protocols and Mental Toughness 1:05:13 Andrew's Next Races 1:13:38 Accomplishments and Inspiration 1:12:10 Andrew's Health Practices Disclaimer: This podcast is for informational purposes only and does not provide medical advice. It is not intended for diagnosing or treating any health condition. Always consult a licensed healthcare professional before making health or wellness decisions. Gary Brecka is the owner of Ultimate Human, LLC which operates The Ultimate Human podcast and promotes certain third-party products used by Gary Brecka in his personal health and wellness protocols and daily life and for which Ultimate Human LLC and / or Gary Brecka directly or indirectly holds an economic interest or receives compensation.  Accordingly, statements made by Gary Brecka and others (including on The Ultimate Human podcast) may be considered promotional in nature. Learn more about your ad choices. Visit megaphone.fm/adchoices

What if the future of women's longevity wasn't about fighting aging—but teaching the body how to adapt, regenerate, and thrive? In this deeply insightful episode of The Girlfriend Doctor Show, Dr. Anna Cabeca sits down with renowned longevity and regenerative medicine expert Dr. Kathleen O'Neil to unpack the cutting-edge science—and timeless fundamentals—behind women's biohacking, immune resilience, and healthy aging. Dr. O'Neil shares her extraordinary journey from pathology and the morgue to elite performance medicine, explaining how understanding why people die transformed how she helps patients live longer, stronger lives. Together, they explore immune modulation, peptides, GLP-1s, light and dark therapy, bone regeneration, adrenal health, energy medicine, and why balance—not extremes—is the true secret to longevity. From menopause and bone loss to hyperbaric oxygen therapy, peptides like oxytocin and thymosin, and the power of adaptability, this episode is a masterclass in personalized, ethical, regenerative medicine for women at every stage of life. If you're curious about biohacking beyond the hype—and want grounded, science-backed strategies that actually work—this conversation is for you.     Key Timestamps 00:01:00 – Welcome & introduction to longevity and regenerative medicine 04:05 – Dr. O'Neill's time in the morgue and what it taught her about immunity, aging, and silent disease 08:15 – The immune system explained: friend vs. foe, gut training, adaptability, and immune modulation 12:18 – Light, dark, melatonin, oxytocin & why darkness is essential for regeneration 13:19 – Feasting, fasting, and the paradoxes that build resilience and adaptability 16:04 – GLP-1s, peptides, and why dosage variability matters for long-term results 21:14 – Energy medicine, biochargers, frequency, vibration & photobiomodulation 24:10 – Adrenal burnout, cortisol dysregulation, and immune collapse 28:17 – Bone loss, ovarian aging clocks, and why prevention must start earlier 30:04 – Bone health, muscle, oxytocin & rebuilding resilience after menopause 36:17 – Regenerative medicine, stem cells, and ethical innovation in longevity care 40:41 – Inside a cutting-edge regenerative medicine clinic 41:02 – Hyperbaric oxygen therapy, lymphatic drainage & advanced recovery tools 45:18 – Personalized medicine, foundations first, adaptability & final takeaways     Memorable Quotes "Longevity is really gerotherapeutics—preventing aging by teaching the body how to regenerate." – Dr. Kathleen O'Neil "You can't hack your life without doing the fundamentals." – Dr. Kathleen O'Neil "Balance—light and dark, stress and recovery—is what creates adaptability." – Dr. Kathleen O'Neil "The immune system is a living medication inside us." – Dr. Kathleen O'Neil "Everything I do today is serving the version of myself I'll be in the future." – Dr. Anna Cabeca     Connect With Guest Dr. Kathleen O'Neil, MD Website: treatwellness.boston Instagram: @treatwellness_ About Dr. O'Neil: Dr. Kathleen O'Neil earned her M.D. from Boston University School of Medicine (Magna Cum Laude) and trained at Massachusetts General Hospital and Brigham and Women's Hospital. She is a global expert in regenerative and longevity medicine, peptide therapy, GLP-1s, and exosomes, working with elite athletes and professional teams. She is a founding board member of the International Peptide Society and the American Academy of Stem Cell Physicians and previously served as Medical Director of Tom Brady's TB12 Wellness Center.       Connect With Dr. Anna Cabeca

They flipped the food pyramid. And yes, it matters. But the deeper question is the one nobody wants to ask: Why do we keep self-sabotaging our health even when we know better? In this episode, Josh Trent breaks down what changed in the new food pyramid and how it changes the baseline for the modern diet. He also goes into where the real healing lives: cravings, emotional patterns, insulin resistance, and the identity level loops underneath it all. In this episode, Josh Trent uncovers: (00:00) They flipped the food pyramid (00:55) The 40-year experiment and why it shaped your cravings (06:45) The fat lie and what it did to the body (10:20) What's missing: fermented foods (12:34) What's really missing: insulin resistance and meal timing (13:32) Cravings as a pattern and spiritual signal (14:43) Four moves to break the loop Disclaimer: This episode is educational. It's not medical advice.

What if I told you that fibromyalgia and chronic fatigue aren't actually diseases, but symptoms of something hiding in plain sight? My guest today is Dr. Peter Osborne, known as "The Gluten Free Warrior," and he's about to blow your mind with what he's discovered about mold toxicity. If you've been struggling with autoimmune symptoms that won't budge despite making all the right diet changes, this episode might be the missing piece of your puzzle. Dr. Osborne breaks down the three distinct ways mold affects your health (hint: it's not just allergies), why those quick air tests are basically useless, and the shocking reality that at least 50% of buildings have water damage issues. We also dive into his six non-negotiable fundamentals for health that everyone needs to hear. This conversation could literally save your life or the life of someone you love. For the complete show notes, links and transcripts, visit inspiredliving.show/227

Welcome to today's ICYMI, where we kick off the week with a quick game-changing tip from past episodes that you might have missed. If the January blues have hit and Seasonal Affective Disorder has you crashing out, we've got you. Winter can leave us feeling exhausted, sad, unmotivated, and plagued by insomnia, so we're throwing it back to biohacking expert Chloe Deutscher to break down what actually helps, from light therapy and SAD lamps to sleep regulation, overcoming insomnia, and supplements that naturally support mood + serotonin.Chloe is a chemical engineer who has dedicated her career to the intersection of science, consciousness, and mental health. She's the co-founder and the CEO of Liquid Culture, a biotech company focused on novel fungi manufacturing and developing innovative products for optimal wellbeing. She shares her actionable tips, knowledge, and experience in the fields of biohacking, mental health, and psychedelics on her popular TikTok account, where she empowers people to overcome mental health challenges like ADHD, anxiety, and depression. Listen to our full episode here.Tune in every Monday for an expert dose of life advice in under 10 minutes.For advertising and sponsorship inquiries, please contact Frequency Podcast Network. Sign up for our monthly adulting newsletter:teachmehowtoadult.ca/newsletter Follow us on the ‘gram:@teachmehowtoadultmedia@gillian.bernerFollow on TikTok: @teachmehowtoadultSubscribe on YouTube

One freezing sip on a Tibetan mountain rewired his hunger, silenced cravings, and unlocked a kind of fat-burning “switch” no doctor ever mentioned. What happened next—Silicon Valley obsession, a global butter shortage, and a new theory of weight loss—might change how you see food forever.The only coffee I drink: Danger Coffee: https://dangercoffee.com/DAVE15Thank you to our sponsors! - GOT MOLD? | Go to http://gotmold.com/shop and use DAVE10 to save 10% and see what's in your air. - EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE for 40% off.Resources: • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Join My Low-Oxalate 30-Day Challenge: https://daveasprey.com/2026-low-ox-reset/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Connect with Dave Asprey!Website: https://daveasprey.comTikTok: https://www.tiktok.com/@daveaspreyofficialInstagram: https://www.instagram.com/dave.asprey/Facebook: https://www.facebook.com/Daveaspreyofficial/X: https://x.com/daveaspreyYouTube: https://www.youtube.com/c/daveaspreybprThe Human Upgrade Podcast: Instagram: https://www.instagram.com/TheHumanUpgradePodcast/ Facebook: https://m.facebook.com/Thehumanupgrade/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Dr. Pinkston and metabolic expert Jim LaValle explain why Heart Rate Variability (HRV) is the ultimate metric for stress and aging. Learn how to track your HRV, avoid the "caffeine trap," and use simple breathing and movement techniques to retrain your nervous system for a longer, healthier life.See omnystudio.com/listener for privacy information.

This drug has been misunderstood for decades, and that confusion is costing people focus, learning speed, and cognitive performance. In this episode, you'll learn why nicotine itself is not the problem, why delivery method and dose change EVERYTHING, and how oral nicotine can be used strategically for biohacking brain optimization, neuroplasticity, and human performance in a healthy and safe way. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with David Renteln, Co Founder and CEO of LUCY Nicotine, a company pioneering science led alternatives for adult nicotine users who want better options. Before launching LUCY, David was also a co founder of Soylent, where he helped pioneer new approaches to functional nutrition and metabolism. Together, Dave and David break down how nicotine works in the brain through acetylcholine and dopamine, why speed of absorption determines addiction risk, and how nicotine affects learning, memory, motivation, and mood. The conversation also covers sleep optimization, mitochondrial signaling, tolerance, cycling strategies, and why modern regulation often slows innovation in functional medicine, anti aging science, and human performance.You'll Learn: • Why nicotine itself is not the same as smoking or vaping • How delivery speed changes addiction risk and brain response • How nicotine supports learning, focus, and neuroplasticity • Why acetylcholine matters for memory and brain optimization • How to think about dosing, cycling, and tolerance safely • How nicotine stacks with caffeine, nootropics, and Danger Coffee • The relationship between nicotine, sleep architecture, and REM • Why harm reduction matters for longevity and mitochondrial health • How nicotine fits into a Smarter Not Harder biohacking strategy Dave Asprey is a four time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Thank you to our sponsors! -Lucy! Get a 20% discount by using code ‘Dave' at https://lucy.co/# Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: nicotine podcast, nicotine nootropic, oral nicotine benefits, nicotine brain optimization, nicotine acetylcholine dopamine, nicotine learning memory, nicotine addiction risk, nicotine pouches vs smoking, LUCY nicotine, david renteln lucy, david renteln nicotine, lucy nicotine pouches, harm reduction nicotine, nicotine biohacking, nicotine human performance, nicotine longevity, nicotine neuroplasticity, nicotine sleep optimization, nicotine tolerance cycling, caffeine nicotine stack, danger coffee nicotine, dave asprey nicotine, dave asprey lucy, nootropics nicotine, functional medicine nicotine Resources: • HeartMath | Go to https://www.heartmath.com/dave to save 15% off. • LYMA | Go to https://lyma.sjv.io/gOQ545 and use code DAVE10 for 10% off the LYMA Laser. • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Join My Low-Oxalate 30-Day Challenge: https://daveasprey.com/2026-low-ox-reset/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com Timestamps: 0:00 – Trailer 1:10 – Origin Story 2:20 – Product Forms & Usage 3:52 – Effects & Mechanisms 9:21 – Dosing & Addiction 15:33 – Memory & Cognitive Benefits 18:57 – Personality & Stacking 21:41 – Quitting Smoking 24:39 – Government Regulation 32:00 – Addiction Philosophy 35:30 – Behavior Change & Routines 39:08 – Final Recommendations See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Most people are struggling in modern relationships, and it is not because they are broken. It is because the systems around them are. In this episode, you'll learn why roughly 65 percent of people operate from insecure attachment, why that quietly destroys energy, trust, and intimacy, and how secure attachment becomes a critical biohacking upgrade for human performance, longevity, and emotional resilience. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Adam Lane Smith, MA Psych, a leading global expert on Attachment Theory and the neurobiology of human bonding. Adam has spent over 16 years studying and working in psychology, helping individuals, couples, and families repair broken relationships, rebuild trust, and develop secure attachment. His work focuses on skill-based nervous system training rather than talk therapy alone, often creating change in months instead of years. He now runs a global coaching practice and is on a mission to bring secure attachment to one billion people worldwide. Together, Dave and Adam break down why modern dating, career pressure, and social isolation have produced a generation of adults who feel emotionally exhausted, disconnected, and stuck in survival mode. They explain how insecure attachment keeps people operating at low capacity, why bonding hormones like oxytocin and vasopressin regulate stress, sleep optimization, and emotional stability, and how broken attachment patterns sabotage metabolism, focus, and recovery. The conversation also covers AI companionship, dating apps, community collapse, and why no supplement, nootropic, fasting protocol, ketosis strategy, or carnivore diet can fully compensate for unsafe nervous systems. You'll Learn: • Why 65 percent of people struggle with modern relationships • How insecure attachment caps energy, focus, and emotional resilience • Why secure attachment matters more as you age, not less • How bonding hormones regulate stress, sleep, and recovery • Why high performers still burn out without nervous system safety • How men and women experience attachment and regulation differently • Why AI and dating apps can worsen disconnection if used poorly • How community and shared purpose rebuild secure attachment • Why supplements and nootropics cannot replace real connection • Where to start if you want stronger relationships and higher capacity Dave Asprey is a four time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Thank you to our sponsors! -KillSwitch | If you're ready for the best sleep of your life, order now at https://www.switchsupplements.com and use code DAVE for 20% off. -Screenfit | Get your at-home eye training program for 40% off using code DAVE at https://www.screenfit.com/dave. -MTE | Get 20% off MTE at https://www.getmte.com/dave using code DAVE. -Timeline | Go to https://www.timeline.com/dave and get 35% off a subscription with their New Year offer. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: adam lane smith, adam lane smith attachment theory, adam lane smith secure attachment, adam lane smith relationships, attachment theory podcast, secure vs insecure attachment, nervous system regulation relationships, oxytocin vasopressin bonding, modern dating psychology, relationship burnout, loneliness epidemic, attachment styles explained, biohacking relationships, dave asprey adam lane smith, dave asprey relationships, human performance psychology, midlife purpose and relationships, aging mindset, adam land smith dave asprey relationships Resources: • Get a discount on any of Adam's courses with code “daveasprey10” at checkout! https://adamlanesmith.com/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Join My Low-Oxalate 30-Day Challenge: https://daveasprey.com/2026-low-ox-reset/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 – Trailer 2:54 – The 30% Capacity Problem 4:19 – Historical Breakdown of Human Connection 9:31 – Building Pseudo-Families & Tribes 15:09 – The Modern Dating Problem 19:21 – Solutions for Women 26:49 – The Four Levels of Safety & Peace 33:04 – Solutions for Men 37:45 – Building Community & Finding Partners 45:26 – Marriage, Partnership & Legacy 52:23 – The Future & Social Culling 1:03:18 – Red Flags vs Green Flags in Dating 1:07:23 – Dating After 50 See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode, Dr. Will Cole sits down with biohacking pioneer Dave Asprey to explore meditation, mitochondria, AI-driven fitness, and nervous system health. Dave shares why his book Heavily Meditated is his most important work yet, how recovery matters more than overtraining, and why meditation is about learning to control your internal state. They also discuss how mitochondria influence emotions and perception, the future of exercise, and what it really means to optimize human performance. For all links mentioned in this episode, visit www.drwillcole.com/podcast.Please note that this episode may contain paid endorsements and advertisements for products and services. Individuals on the show may have a direct or indirect financial interest in products or services referred to in this episode.Sponsors:Use code BEINGWELL at monarch.com for half off your first year. That's 50% off your first year at monarch.com with code BEINGWELL. Text ABW to 64000 to get twenty percent off all IQBAR products, plus FREE shipping. Message and data rates may apply.Visit ProlonLife.com/willcole to claim your 15% discount and your bonus gift.Wake up with clearer skin, smoother hair, and cooler sleep. Use code WILLCOLE for an extra 30% off at blissy.com/WILLCOLE. Visit YourReformer.com to shop their New Year sale on now to save.Produced by Dear Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Text us a comment or question!Over 50 and frustrated with your progress? Book a free Silver Edge Clarity Call and get a clear plan forward.https://go.silveredgefitness.com/clarirty-call If you're over 50 and you feel like your body is starting to “fight back”… More aches. More stiffness. Slower recovery. Less energy. You're not crazy — and you're definitely not broken. In today's episode, Kevin sits down with Kris Gethin — world-renowned hybrid athlete, elite performance coach, and one of the most disciplined humans on the planet — to break down what it actually takes to stay lean, strong, athletic, and pain-free after 50. Kris is a drug-free professional bodybuilder, IRONMAN triathlete, ultramarathon runner, and Spartan competitor… and at 51 years old, he's still training like a savage — while also prioritizing longevity and recovery like a pro. This conversation is packed with no-BS advice on training, nutrition, inflammation, stress, and why most people are making fat loss harder than it needs to be. In This Episode, You'll Learn:Why “looking fit” doesn't always mean you're healthyThe biggest training adjustment Kris made after 50 (and why it matters)How to train hard without destroying your joints and recoveryWhy strength training is the foundation for longevity and metabolic healthThe difference between fitness, health, and performanceWhat Kris eats to stay lean, fueled, and strong (without obsessing over macros)The real reason most people struggle with inflammation after 50How stress, sleep, and cortisol can make fat loss feel impossibleKris's take on biohacking (and why the basics still matter most)The truth about peptides, GLP-1s, and “shortcuts” — and who they're actually forA powerful mindset shift for people who struggle with motivation and discipline Connect with Kris GethinWebsite: https://www.krisgethin.comInstagram: https://www.instagram.com/krisgethin/(He shares training, nutrition, discipline, and longevity strategies daily.)YouTube: https://www.youtube.com/krisgethin Enjoyed This Episode?If this episode fired you up, do me a favor:⭐️ Leave a quick review and share this episode with a friend who's over 50 and wants to feel strong again.Over 50 and frustrated with your progress? Click HERE to book a free Silver Edge Clarity Call and get a clear plan forward. Over 50 and frustrated with your progress? Book a free Silver Edge Clarity Call and get a clear plan forward.

In this episode of Health Matters, host Courtney Allison is joined by Dr. Rekha Kumar, endocrinologist and primary care physician at NewYork-Presbyterian and Weill Cornell Medicine, to unpack the science behind aging well. They discuss biohacking, longevity, and health span, separating evidence-based strategies from social media hype and exploring what truly helps us age well.What You'll Learn in This EpisodeWhat “biohacking” really means● How biohacking ranges from simple lifestyle optimization to high-tech, experimental interventions● The difference between lifespan (how long you live) and health span (how long you live well)The Longevity Pyramid● Why the foundation of healthy aging is built on:SleepMovement and strength trainingNutritionStress managementSocial connection● How advanced tools and supplements sit at the top—and why they should never replace the basicsWearables and Tracking● How devices like smartwatches, glucose monitors, and fitness trackers can support behavior change● When tracking becomes counterproductive or stressfulPeptides and “Anti-Aging” Supplements● What's proven (e.g., metformin, GLP-1 receptor agonists)● What's still experimental or under-studied (BPC-157, sermorelin, NAD boosters)Nootropics and Cognitive Enhancers● Everyday nootropics like caffeine● The role of L-theanine for “calm focus”● Myths around perfectly timed caffeine and cortisol rhythmsNutrigenomics and Personalized Nutrition● How genes can influence responses to foods (e.g., lactose intolerance, APOE and saturated fat)● Why many direct-to-consumer genetic tests may overpromiseThe Gut Microbiome● The role of Akkermansia muciniphila in metabolic health● How medications like metformin and GLP-1s may positively shift gut bacteria● What's still unknown about probiotic supplementationGenetic and Biomarker Testing● The difference between actionable medical insights and “information overload”● Why results of unknown significance can cause unnecessary anxietyThe Big Takeaways● There are no true shortcuts to longevity● Sustainable habits beat quick fixes● Our biology is built for rhythms, not constant optimizationFeatured ExpertAbout Rekha B. Kumar, M.D., M.S.Dr. Rekha B. Kumar is an attending endocrinologist at NewYork-Presbyterian/Weill Cornell Medical Center and an associate professor of Clinical Medicine at Weill Cornell Medicine. She specializes in adult primary care and endocrinology and has academic expertise in the diagnosis and treatment of various endocrine disorders, including obesity/weight management, type 2 diabetes, polycystic ovarian syndrome (PCOS), thyroid disorders, as well as metabolic bone disease.Dr. Kumar completed her undergraduate studies at Duke University and received her masters degree in Physiology from Georgetown University. She received her M.D. from New York Medical College and completed her residency training in Internal Medicine at NewYork-Presbyterian/Weill Cornell Medical Center. Dr. Kumar obtained her clinical fellowship in the combined Diabetes, Endocrinology, and Metabolism program at the NewYork-Presbyterian/Weill Cornell Medical Center and the Memorial Sloan Kettering Cancer Center. Dr. Kumar is Board Certified in Internal Medicine, Endocrinology, Diabetes, & Metabolism, and Obesity Medicine.Coming Up NextIn the next episode of Health Matters, we'll explore brain health and the short- and long-term effects of alcohol on the brain with Dr. Hugh Cahill. Subscribe and follow Health Matters on Apple Podcasts, Spotify, or wherever you listen to stay up to date with expert-driven conversations on living well at every stage of life.About Health MattersHealth Matters is your bi-weekly dose of health and wellness information, from the leading experts. Join host Courtney Allison to get news you can use in your own life. New episodes drop each Wednesday.If you are looking for practical health tips and trustworthy information from world-class doctors and medical experts you will enjoy listening to Health Matters. Health Matters was created to share stories of science, care, and wellness that are happening every day at NewYork-Presbyterian, one of the nation's most comprehensive, integrated academic healthcare systems. In keeping with NewYork-Presbyterian's long legacy of medical breakthroughs and innovation, Health Matters features the latest news, insights, and health tips from our trusted experts; inspiring first-hand accounts from patients and caregivers; and updates on the latest research and innovations in patient care, all in collaboration with our renowned medical schools, Columbia and Weill Cornell Medicine.To learn more visit: https://healthmatters.nyp.org

Mood, motivation, and emotional resilience are not personality traits. They are biological systems. In this episode, you'll get the 12 greatest mood boosters on Earth, not as a clickbait supplement list, but as the real biological levers that control dopamine sensitivity, hormones, neuroplasticity, and energy production.Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down in Dubai with friend of the show, Lucas Aoun, founder of Ergogenic Health and INB4, for a deep, experience driven conversation on dopamine, mood, and performance. Lucas is Australia's leading biohacker, now based in Dubai, with a background in exercise science, naturopathy, and pharmacology. He is globally recognized for his work in dopamine regulation, testosterone optimization, and neurohormonal performance, and for rigorously testing protocols before recommending them. Together, Dave and Lucas explore how dopamine receptor upregulation changes motivation, mood, and resilience more effectively than stimulants alone. They break down compounds and systems discussed in the episode including solbutiamine, lithium orotate, sarcosine, inositol, uridine, testosterone, growth hormone, ketamine pathways, thyroid optimization, liver health, sleep quality, and desire regulation. The conversation also examines GLP-1 drugs, why they can blunt motivation, and how to think more strategically about long term mood and energy. This episode connects neuroscience, functional medicine, hormone biology, nootropics, and advanced biohacking ethics into a single framework for improving how you feel and function every day. Dave and Lucas also explain why experimentation requires guardrails, how to avoid tolerance and emotional flattening, and why upgrading baseline biology beats chasing quick fixes. You'll Learn: • Why dopamine sensitivity matters more than dopamine levels • How mood, motivation, and desire are regulated biologically • Which compounds and systems came up as major mood levers • How testosterone and growth hormone influence emotional resilience • Why some longevity drugs may reduce motivation and drive • How sleep depth and mitochondrial function affect mood • The role of neuroplasticity in emotional regulation • Why strategic testing beats random supplementation • How to improve mood without addiction or burnout • Where to start if you want sustainable energy and motivation Dave Asprey is a four time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Thank you to our sponsors! -LYMA | Go to https://lyma.sjv.io/gOQ545 and use code DAVE10 for 10% off the LYMA Laser. -Vibrant Blue Oils | Grab a full-size bottle for over 50% off at https://vibrantblueoils.com/dave. -AirDoctor | Go to https://airdoctorpro.com/daveasprey and save up to $300 on Air Purifiers Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: dopamine sensitivity, dopamine receptors, mood boosters, motivation biology, dopamine supplements, natural mood boosters, biohacking dopamine, emotional resilience, anhedonia dopamine, focus and motivation, testosterone mood, growth hormone mood, ketamine alternatives, neuroplasticity mood, sleep and mood regulation, mitochondrial energy mood, GLP-1 dopamine effects, desire regulation, hormone optimization mood, dave asprey dopamine, lucas aoun biohacking, smarter not harder mood Resources: • Lucas's YouTube: https://www.youtube.com/c/boostyourbiology/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Join My Low-Oxalate 30-Day Challenge: https://daveasprey.com/2026-low-ox-reset/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 – Introduction & Dopamine Discussion 2:55 – Dopamine Compounds 6:29 – Lithium & Emotional Regulation 9:37 – Pain, Suffering & Biohacking Ethics 13:56 – Trumpet Vine & Amphetamine Alternatives 17:55 – Nootropics & Experimentation 20:27 – Sarcosine & Fast-Acting Antidepressants 23:53 – Sugar Tolerance & Inositol 27:01 – Testosterone & Hormone Optimization 33:48 – Natural Testosterone Optimization 37:36 – Anabolic Agents & SARMs 39:38 – Growth Hormone & MK-677 40:38 – Cabergoline & Prolactin 49:03 – Thyroid & Reverse T3 51:18 – Liver Health & Tudca 54:53 – Ketamine & Psychedelics 1:02:01 – Experimental Compounds 1:07:05 – Advanced Peptides & Compounds 1:13:19 – GLP-1 Agonists & Dopamine 1:14:44 – Closing Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Most people think fasting is just about skipping breakfast. But what if 72 hours without food could actually reverse aging?In this video, Dave Asprey breaks down what really happens when you fast for 3 days—and why short fasts don't reach the deep repair zone your body is built for. Thank you to our sponsors! -HeartMath | Go to https://www.heartmath.com/dave to save 15% off.-Generation Lab | Go to http://generationlab.com/, use code Dave20 for $20 off, and see what your body's really doing behind the surface.Chapters0:00 - Why 16-hour fasts don't reach real fat burning0:54 - The myth of aging and what doctors overlook1:48 - How modern life damages your mitochondria2:48 - How fasting restores your body's repair mode3:39 - Understanding the phases of fasting4:58 - Why short fasts cut results short5:34 - Day 1 of fasting6:45 - Day 2 of fasting7:22 - Day 3 of fasting8:24 - Common fasting mistakes that harm your body9:35 - How to prepare before your fast10:31 - The right way to refeed afterward11:14 - Listening to your body's signals and responsesResources: • Go To: www.qualialife.com/humanupgrade for an automatic extra 15% discount to try Qualia Creatine. • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Join My Low-Oxalate 30-Day Challenge: https://daveasprey.com/2026-low-ox-reset/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Connect with Dave Asprey!Website: https://daveasprey.comTikTok: https://www.tiktok.com/@daveaspreyofficialInstagram: https://www.instagram.com/dave.asprey/Facebook: https://www.facebook.com/Daveaspreyofficial/X: https://x.com/daveaspreyYouTube: https://www.youtube.com/c/daveaspreybprThe Human Upgrade Podcast: Instagram: https://www.instagram.com/TheHumanUpgradePodcast/ Facebook: https://m.facebook.com/Thehumanupgrade/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Back in 2024 with Calley Means at South by Southwest, we sat down and talked about his mission to flip the old American food pyramid upside down for the greater good. Well guess what, the pressure is finally working! This rerun is the ultimate receipt that focus, repetition, and smart lobbying for human health can still move the needle! Host Dave Asprey sits down with Calley Means, entrepreneur, policy advocate, and co-author of Good Energy. Together, they break down how the U.S. healthcare system became a sick-care system, why ultra-processed food dominates public policy, and how individuals can reclaim autonomy over their biology. From CGMs and metabolic health to food subsidies, lobbying, and free speech, this episode challenges deeply held assumptions about medicine, nutrition, and personal responsibility.You'll Learn: • Why chronic disease is the most profitable business model in modern history • How metabolic dysfunction drives obesity, diabetes, depression, and infertility • Why ultra-processed food sits at the root of America's health collapse • How CGMs and metabolic data threaten entrenched healthcare incentives • What “food is medicine” really means and where it gets weaponized • How HSA and FSA dollars can legally support food, exercise, and prevention • Why fixing incentives matters more than blaming individuals • How reclaiming health autonomy is tied to free speech and human resilience Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: Calley Means Good Energy, Calley Means interview, Good Energy metabolic health, metabolic dysfunction America, ultra processed food policy, food is medicine debate, healthcare incentives crisis, chronic disease economics, insulin resistance epidemic, CGM health data access, metabolic health lobbying, seed oils sugar inflammation, glyphosate food system, HSA food exercise eligibility, health autonomy biohacking, metabolic freedom podcast, american food pyramid, rfk food pyramid, 2026 food pyramid Thank you to our sponsors! Essentia | Go to https://myessentia.com/dave and use code DAVE for $100 off The Dave Asprey Upgrade. Resources: • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Join My Low-Oxalate 30-Day Challenge: https://daveasprey.com/2026-low-ox-reset/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 – Introduction 2:11 – Mom's Cancer Story 4:24 – Healthcare System Incentives 10:14 – TruMed and Food as Medicine 15:51 – FDA and IRS Pushback 17:25 – Political Solutions and RFK 19:49 – Childhood Obesity Crisis 21:49 – The Chronic Disease Industry 26:54 – State of Emergency Proposal 29:07 – Healthcare Industry Mindset 31:30 – COVID and Metabolic Health 32:28 – Taking Back Health Autonomy 34:16 – Medical System Collusion 35:56 – Research Corruption 37:21 – Pharma Bribes and Conflicts 40:17 – Ozempic and Civil Rights Groups 42:35 – Personal Mission and Mom's Legacy 50:16 – Media Power and Free Speech 54:00 – Weaponizing Social Justice 55:16 – Systemic Poisoning of the Population 57:37 – Technology as a Health Solution 1:03:20 – Regenerative Farming and Robotics 1:06:34 – Controlling the Food Supply 1:10:18 – Closing Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Turn online alignment into an offline community — join us at TheWayFwrd.com to connect with like-minded people near you.We obsess over food and supplements. Meanwhile, the light we live under every day is quietly wrecking our biology.In this episode, I sit down with Matt Maruca, founder and CEO of Ra Optics, to discuss how artificial light, blue light, and disrupted circadian rhythm quietly impact energy, sleep, and long-term health. Matt shares how a years-long personal health journey led him to study circadian biology and the essential role light plays in human physiology.We explore why modern indoor environments are so biologically mismatched, how LED lighting and screens affect mitochondrial health, and why sunlight is powerful but not something to mindlessly overdo. Matt also explains how light influences hormones, mental health, and recovery, and why most wellness conversations miss this entirely.Beyond the science, we touch on Matt's broader work teaching how to think differently about light exposure, health, and performance.If you're interested in biohacking, sleep optimization, blue light, or understanding why your nervous system feels constantly overstimulated, this episode will shift how you see your environment.You'll Learn:[00:00:00] Introduction[00:08:02] Matt's childhood health struggles, and the discovery that changed everything[00:12:23] Diet alone can't fix your health, so what is at the root of chronic disease?[00:16:34] The fourth phase of water inside your cells and why 40% of sunlight is designed specifically to structure it[00:18:33]  The devolution of artificial light — from fire-like incandescents to blue-heavy, infrared-stripped “junk light” LEDs[00:39:16] Blue light, your circadian rhythm and mental illness[00:45:22] Why "more sun is better" is wrong[00:57:15] How a chance encounter at an event turned a garage tinting operation into Ra Optics[01:13:19] Why traditional sunglasses blunt the health benefits of sunlight, and the lens innovation designed to fix that[01:20:58] What makes Ra Optics different from other blue light blocking glasses on the market[01:30:02] Why doing all the right things still left Matt miserable, and the event that created a huge shift[02:09:27] The hidden problems with "circadian bulbs" on the current market[02:20:12] How to protect your light environment and stay healthy while travelingResources Mentioned:The Way Forward episode on the Hidden Dangers of EMFs, Artificial Light, & Wifi (How To Avoid Them) featuring Tristan Scott | YouTubeThe Way Forward episode on Circadian Biology, Leptin, & Light featuring Sarah Kleiner | YouTubeThe Life Stylist episode on Extreme Biohacking: Millennial Edition with Matt Maruca | Listen NowA mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine by Wallace, D | ArticleThe Fourth Phase of Water by Gerald Pollack | Book or AudiobookThe Hard Thing About Hard Things by Ben Horowitz | Book or AudiobookThe Lean Startup by Eric Ries | Book or AudiobookThe 4-Hour Workweek by Timothy Ferriss | Book or AudiobookAutobiography of a Yogi by Paramhansa Yogananda | Book or AudiobookSouth: The ENDURANCE Expedition by Ernest Shackleton | Book or AudiobookSaunaSpace | WebsiteFind more from Matt:The Light Diet Podcast | Spotify or AppleThe Light Diet | InstagramRa Optics | InstagramFind more from Alec:Alec Zeck | InstagramAlec Zeck | XThe Way Forward | InstagramThe Way Forward is Sponsored By:New Biology Clinic: Redefine Health from the Ground UpExperience tailored terrain-based health services with consults, livestreams, movement classes, and more. Visit www.NewBiologyClinic.com and use code THEWAYFORWARD (case sensitive) for $50 off activation. Members get the $150 fee waived

Creatine is a hot subject right now, but I'm guessing you might not know as much about it as you could. Well step into a new creatine masterclass with our friends from Qualia. This episode shows you why it is not just for muscle, but one of the most powerful and well studied upgrades for brain energy, metabolism, sleep resilience, and long term human performance. You will learn how creatine supports mitochondria, buffers ATP, reduces cravings, and helps you think, train, and recover with more energy instead of relying on willpower. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Greg Kelly for a deep, practical masterclass on creatine and energy biology. Greg Kelly is a naturopathic physician, functional medicine expert, and longtime researcher in supplements and nootropics. He has spent decades studying creatine, mitochondrial function, cognition, and performance, and has contributed to peer reviewed research while working directly with athletes, clinicians, and high performers. Together, Dave and Greg break down how creatine works at the cellular level, why it matters for cognition, emotional regulation, and metabolism, and how it supports the brain and body during stress, sleep deprivation, dieting, and recovery. They explore neuroplasticity, ATP production, magnesium, methylation, and why energy availability drives discipline, focus, and resilience more effectively than willpower alone. They also explain why creatine matters for women, aging adults, and people dealing with fatigue or obesity, and how creatine supports brain function even when muscle mass is low. This conversation connects bodybuilding research with modern longevity science, nootropics, functional medicine, and sleep optimization. Dave and Greg also expose why creatine quality matters, how contaminants can impair mitochondrial function, why some products fail label claims, and how to choose forms that absorb better and cause less bloating. Practical strategies like dosing, timing, stacking with magnesium, and using creatine with hot coffee are all covered, including why Dave uses it with Danger Coffee as part of his Smarter Not Harder approach. You'll Learn: • Why creatine acts as an ATP buffer for both muscles and the brain • How mitochondria drive cognition, metabolism, and emotional regulation • The real dosing debate from low daily maintenance to higher cognitive doses • Why women often need more creatine than men • How creatine supports performance during sleep deprivation and sleep debt • The link between magnesium, creatine phosphate, and ATP production • How methylation and TMG relate to creatine synthesis and timing • Why creatine can reduce cravings by improving cellular energy • How low quality creatine and contaminants can damage mitochondrial function • When creatine matters most for longevity, resilience, and human performance Dave Asprey is a four time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Thank you to our sponsors! • Screenfit | Get your at-home eye training program for 40% off using code DAVE at https://www.screenfit.com/dave • ECHO Water | Go to http://echowater.com/dave and use code DAVE10 for 10% off your ECHO Flask • NeuroVeda Health | Go to https://www.neurovedahealth.com/aspery to learn more and book your week • STEMREGEN | Go to http://stemregen.co/dave30 and use code DAVE30 for 30% off your next order Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: creatine brain energy, creatine ATP buffering, creatine mitochondria, creatine cognitive performance, creatine supplementation science, creatine dosing cognition, creatine sleep deprivation, creatine emotional regulation, creatine cravings metabolism, creatine fatigue brain, creatine women dosing, creatine longevity science, creatine nootropics, creatine brain optimization, ATP brain energy, mitochondrial energy production, magnesium creatine ATP, creatine methylation TMG, creatine bioavailability, danger coffee creatine, dave asprey creatine, greg kelly creatine, smarter not harder energy Resources: • Go To: www.qualialife.com/humanupgrade for an automatic extra 15% discount to try Qualia Creatine. • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Join My Low-Oxalate 30-Day Challenge: https://daveasprey.com/2026-low-ox-reset/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 00:00 – Trailer 01:25 – Introduction 04:57 – History of Creatine 07:47 – How Creatine Works 12:00 – Dietary Sources of Creatine 13:30 – Creatine Dosing Guidelines 18:08 – Cognitive Benefits of Creatine 19:36 – Bodybuilding vs Biohacking Doses 22:08 – Kidney Function and Safety 24:42 – Sleep, Recovery, and Creatine 26:08 – Bloating and Absorption Issues 30:53 – Timing, Caffeine, and Coffee Stacks 34:07 – Different Forms of Creatine 43:06 – Weight Loss, Obesity, and Metabolism 45:50 – Testosterone and Hormones 47:47 – Women and the Menstrual Cycle 50:12 – Pregnancy and Fertility 53:44 – Magnesium and ATP Connection 56:17 – Methylation and TMG 01:01:18 – Creatine Quality and Contaminants 01:09:17 – Practical Creatine Tips 01:15:46 – Creatine for Kids and Teenagers See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Links referenced in this episode are below:Layne's website: https://www.lvwellnessconsulting.comFree Gut Rescue Guide: https://www.lvwellnessconsulting.com/gut-guideBook A Call with Layne: https://www.lvwellnessconsulting.com/applicationLayne's Instagram: https://www.instagram.com/layne_vanlieshout/Learn more / join us in the new ALL IN EXPERIENCE (use code ALLINWITHALLIE to save 25%):http://www.allieireeves.com/all-in-experience

You're about to hear one of the most honest longevity conversations ever recorded. This co hosted episode brings together two longevity leaders with opposing views on how long humans can live, yet enormous respect for each other and the science. Recorded live at Eudemonia, this discussion gives you clear frameworks for longevity, biohacking, human performance, and anti aging without all the tribal thinking that can plague modern health conversations! Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Dan Buettner for a rare co hosted podcast that explores where biohacking and Blue Zones philosophy clash and where they surprisingly align. Dan Buettner is a National Geographic Explorer, Emmy Award winning producer, and five time New York Times bestselling author. He is best known for identifying the Blue Zones, regions of the world where people live the longest and healthiest lives. His research has reshaped cities, healthcare systems, and insurance models across the United States, improving health outcomes for more than 10 million Americans. His Netflix series Live to 100: Secrets of the Blue Zones earned six Emmy nominations and won three. Dan is also an accomplished endurance athlete with three Guinness World Records in distance cycling. Together, Dave and Dan debate the true limits of human lifespan, whether longevity is driven more by environment or intervention, and how modern tools like AI, functional medicine, supplements, fasting, ketosis, and sleep optimization compare to walkable communities, movement, and purpose. They explore mitochondria, neuroplasticity, metabolism, brain optimization, and why Smarter Not Harder applies whether you follow a carnivore leaning diet, a bean based diet, or something in between. This episode gives you both sides of the longevity argument and lets you decide what fits your biology, values, and goals. You'll Learn: • Why Dan believes average human lifespan likely tops out in the mid 90s and how Blue Zones support longevity without chronic disease • Why Host Dave Asprey believes biohacking, AI, and modern science could push longevity toward 150, 180, or beyond • How environmental design hacks unconscious behavior more effectively than willpower • The overlooked role of light, darkness, and circadian rhythm in sleep optimization and human performance • How fasting and ketosis support longevity when used strategically instead of obsessively • Why mitochondria signaling may matter more than fixing every cell individually • How neuroplasticity and brain optimization influence aging and resilience • Where supplements and nootropics help and where simplicity wins • The real debate around carnivore diets, carbs, beans, metabolism, and longevity • Why community, purpose, and movement remain foundational even in advanced biohacking • How Danger Coffee fits into energy, focus, and Smarter Not Harder performance strategies Dave Asprey is a four time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Thank you to our sponsors! - BodyGuardz | Visit https://www.bodyguardz.com/ and use code DAVE for 25% off. - MASA Chips | Go to https://www.masachips.com/DAVEASPREY and use code DAVEASPREY for 25% off your first order. - Puori | Use code DAVE at http://puori.com/DAVE to get 32% off your Puori Fish Oil when you start a subscription. You save more than $18. - BrainTap | Go to http://braintap.com/dave to get $100 off the BrainTap Power Bundle. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: longevity debate, biohacking vs blue zones, dave asprey dan buettner, human lifespan limits, how long can humans live, anti aging science, blue zones longevity, environment vs intervention longevity, human performance optimization, mitochondria signaling, aging clocks epigenetics, neuroplasticity aging, brain optimization longevity, sleep optimization circadian rhythm, fasting longevity science, intermittent fasting longevity, ketosis metabolism aging, AI longevity tools, AI exercise training, VO2 max lifespan, metabolism optimization, supplements longevity, nootropics brain health, carnivore diet longevity, beans vs meat longevity, protein mTOR aging, functional medicine longevity, community purpose lifespan, movement vs exercise longevity, light exposure circadian health, darkness sleep longevity, daveasprey biohacking, dan buettner blue zones, smarter not harder longevity, danger coffee performance Resources: • Dan's new podcast: https://danbuettner.com/podcast/ • Dan's website: https://danbuettner.com/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 – Trailer 2:50 – Introduction to Dan Buettner 4:59 – Light & Circadian Biology 7:21 – Aging Science & Interventions 13:18 – Community & Social Connection 15:16 – Biohacking Basics 19:04 – Movement & Exercise 21:20 – Diet & Nutrition Philosophy 31:06 – Dave's Daily Diet 33:49 – Salt & Hydration 41:07 – Marketing & Building Bulletproof 49:10 – Rapid Fire Round 55:00 – Closing Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Most men think ED is just a performance issue. It's not. It's one of the earliest warning signs of cardiovascular decline and it often appears years before chest pain, shortness of breath, or heart attack symptoms.Thank you to our sponsors! -EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE for 40% off.-GOT MOLD? | Go to http://gotmold.com/shop and use DAVE10 to save 10% and see what's in your air.Chapters00:00 - The “Legal Blue Pill” Myth & Hidden Danger00:57 - What ED Actually Is (Not the Commercial Version)01:45 - Circulation, Arteries & the Real Root Cause03:27 - The Problem with Relying on ED Pills05:03 - Treat ED as a Cardiovascular Symptom05:55 - Patterns That Reveal Vascular Decline07:10 - The ED–Heart Attack Countdown Window08:14 - How To Fix This Problem10:10 - Microdosing Cialis for Vascular Support10:45 - Aspirin as Another Option11:15 - Lifestyle Drivers of Vascular Damage & Solutions13:15 - Movement, Walking & Circulation Basics13:40 - The Mitochondria–Erection Connection15:00 - Recharging Mitochondria16:02 - Chronic Inflammation: The Silent Culprit17:17 - Smoking, Vaping, Obesity & Diabetes18:30 - How To Reduce InflammationResources: • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Connect with Dave Asprey!Website: https://daveasprey.comTikTok: https://www.tiktok.com/@daveaspreyofficialInstagram: https://www.instagram.com/dave.asprey/Facebook: https://www.facebook.com/Daveaspreyofficial/X: https://x.com/daveaspreyYouTube: https://www.youtube.com/c/daveaspreybprThe Human Upgrade Podcast: Instagram: https://www.instagram.com/TheHumanUpgradePodcast/ Facebook: https://m.facebook.com/Thehumanupgrade/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.