Podcasts about Biohacking

How to Reverse Cognitive Decline, Grow Your Hippocampus, and Protect Your Brain from Alzheimer's Disease with Nutrition, Exercise, Sleep, and Stress Reduction Your brain is physically shrinking right now, and most people have no idea it's happening. In this episode, you will discover the exact mechanisms behind cognitive decline, why brain fog is always treatable, and the proven strategies to grow your brain back, protect your memory, and slash your Alzheimer's risk regardless of your genetics. -Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Dr. Majid Fotuhi, a neuroscientist and neurologist who earned his PhD from Johns Hopkins University and his medical degree from Harvard Medical School. He currently serves as an adjunct professor at the Mind/Brain Institute at Johns Hopkins while also teaching at George Washington University and Harvard Medical School. With 37 years of experience in clinical practice, teaching, and neuroscience research, Dr. Fotuhi pioneered the Brain Fitness Program, a multidisciplinary approach to cognitive performance and brain vitality at any age that has produced measurable results documented in peer-reviewed journals. He is the author of three books including the bestselling The Invincible Brain and one of the world's leading experts on neuroplasticity, hippocampus growth, and successful aging. If anyone has earned the right to tell you your brain can get better, it is him. Dr. Fotuhi and Dave break down why Alzheimer's is not a single disease but a soup of modifiable problems, why your lab results can show "normal" while your brain is starving, and how the five pillars of brain health connect directly to longevity, mitochondria function, and human performance. They also get into the brain effects of GLP-1s, the therapeutic promise of psychedelics like psilocybin and ketamine, the role of nootropics and supplements like B12, lithium orotate, and CoQ10, and why your VO2 max may be the single most important number for brain aging. . You'll Learn: Why 97% of Alzheimer's cases involve multiple modifiable causes and what to do about each one How to physically grow your hippocampus through exercise, meditation, and nutrition Why "normal" lab ranges are actively harming millions of people and what optimal actually looks like The 7 everyday things that are shrinking your brain right now How stress, loneliness, and isolation cause measurable brain atrophy Which supplements including B12, lithium orotate, CoQ10, and nootropics support long-term brain health Why VO2 max predicts brain aging better than almost any other marker What psychedelics like psilocybin and ketamine actually do to your brain according to a Johns Hopkins neurologist How the APOE4 gene affects Alzheimer's risk and why exercise can erase that risk entirely Why mitochondria health is the foundation of both brain function and longevity Thank you to our sponsors! - Viome | Check it out at viome.com and use code 10DAVE for 10% off. It's time to stop guessing and start knowing your body. - BrainTap | Go to http://braintap.com/dave to get $100 off the BrainTap Power Bundle. - Pique | Go to Piquelife.com/dave for 20% off. - BodyHealth | Visit BodyHeath.com and use code DAVE20 for 20% off your first purchase Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Majid Fotuhi, Dr. Majid Fotuhi, The Invincible Brain, brain health, cognitive decline, Alzheimer's prevention, hippocampus, neuroplasticity, brain fog, memory loss, APOE4, brain shrinkage, B12 deficiency, lithium orotate, CoQ10, nootropics, VO2 max, mitochondria, longevity, anti-aging, biohacking, brain optimization, sleep optimization, stress reduction, functional medicine, human performance, psilocybin, ketamine, GLP-1, semaglutide, telomeres, BDNF, brain training, cognitive performance Resources: • Learn More About Dr. Fotuhi's Work At: https://drfotuhi.com/ • Purchase Dr. Fotuhi's New Book The Invincible Brain: https://a.co/d/0iHCgPpL • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 00:59 – Intro 03:00 – Cannabis & Nicotine 04:15 – Understanding Alzheimer's 05:38 – Five Pillars Explained 07:55 – Best Cognitive Training 09:08 – Brain Size & Growth 12:36 – B12 & Lab Ranges 17:48 – Head-to-Toe Evaluation 24:17 – Sex & Brain Health 25:43 – Loneliness & Isolation 33:59 – ApoE4 Genetics 35:28 – Alzheimer's Declining 48:44 – Lithium & Brain 59:38 – VO2 Max & Fitness 1:06:42 – Psychedelics 1:09:38 – GLP-1s & Brain 1:12:38 – Closing & Action Steps See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Dr. William Li: Eat to Beat Disease, Extend Longevity, and Hack Your Vascular Health Your body already has a built-in cancer defense system, and the foods you eat can rival prescription drugs at activating it. In this episode, you'll discover what 720,000 living centenarians reveal about longevity, why microplastics are reaching your brain through your nose, and how your blood vessels hold the real key to biological aging. -Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Dr. William Li, an internationally renowned physician, scientist, and two-time New York Times bestselling author of "Eat to Beat Disease" and "Eat to Beat Your Diet." As President and Medical Director of the Angiogenesis Foundation, Dr. Li's groundbreaking research has led to the development of more than 40 new medical treatments impacting care for over 70 diseases including diabetes, heart disease, blindness, and obesity. His TED Talk, "Can We Eat to Starve Cancer?", has surpassed 11 million views, making him one of the most trusted voices at the intersection of functional medicine and food as medicine science. Together they dig into the biology of SuperAgers, the vascular markers that predict how long you'll live, and why flow-mediated dilation may be the most underrated biohacking measurement tool available today. Dave shares what happened after four separate gene therapies, including klotho and VEGF, and Dr. Li explains why your metabolism, mitochondria, and gut microbiome show up in the data on every centenarian ever studied. They also get into the microplastic crisis, the cribriform plate pathway that delivers airborne particles directly to your brain, and why your tongue is the first place your body quietly stores fat. You'll Learn: What centenarian research reveals about immune function, gut health, and vascular resilience Why 50% of food extracts matched or outperformed cancer drugs in head-to-head angiogenesis testing How microplastics travel through your nose directly to your central nervous system What flow-mediated dilation and pulse wave velocity tell you about your true biological age Why your hind-third tongue fat is an overlooked early warning sign for sleep apnea and metabolism problems What Dave's four gene therapies (klotho, VEGF, follistatin) actually did to his body How the vagus nerve connects gut health to brain optimization, stress resilience, and longevity Why genetics now accounts for roughly half of longevity outcomes, and what that means for the future of gene therapy How to use biohacking tools to compound your health the same way you compound financial returns Thank you to our sponsors! - Beyond Wonderland Conference | Oct 13 - 14, 2026. Get your ticket now at wonderlandconference.com. - Amp | If you're ready to make fitness fit into your life, go to amp.ai to check it out - Caldera + Lab | A small habit with big results. Go to CalderaLab.com/DAVE and use code DAVE for 20% off your first order. - Calroy | Go to Calroy.com/DAVE for exclusive discounts on Arterosil HP, Vascanox HP and all Calroy products. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: William Li, Dr. William Li, Eat to Beat Disease, angiogenesis, food as medicine, centenarians, SuperAgers, longevity, anti-aging, biohacking, vascular health, flow-mediated dilation, pulse wave velocity, microplastics, cribriform plate, gene therapy, klotho, VEGF, follistatin, mitochondria, metabolism, gut health, vagus nerve, sleep apnea, functional medicine, human performance, brain optimization, cancer prevention, inflammation, immune system Resources: • Learn More About Dr. Li's Work At: https://drwilliamli.com • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 02:33 – William's Background 06:21 – Food vs. Cancer Drugs 14:09 – Gene Therapy 23:50 – Centenarian Research 27:41 – Stress & the Vagus Nerve 37:31 – Vascular Health 42:34 – Microplastics 53:19 – Novel Biomarkers See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

I used to weigh 300 pounds. I tried every restrictive diet, became a vegan, and trained 90 minutes a day for 18 months with absolute zero results. Everything changed when I drank a cup of yak butter tea at 18,300 feet in Tibet. Within 30 seconds, my severe brain fog lifted, and my metabolism completely shifted.In this video, I break down exactly why adding sugar to your morning coffee is destroying your metabolism, spiking your insulin, and keeping you fat. I explain the hard science behind the alternative: blending "fat cubes" (grass-fed butter) and MCT oil into your coffee. I reveal how this specific combination of butyrate, CLA, and medium-chain triglycerides bypasses traditional digestion to go straight to your liver, instantly converting into ketones for pure brain fuel. You'll learn how eating more fat actually trains your body to burn its own stored fat, allowing me to hit 4.8% body fat at 50 years old with a biological age in my 30s—without hunger, without a 3 PM crash, and without living in the gym.Thank you to our sponsors!Suppgrade Labs | Grab your DAKE and Minerals 101 duo at shopsuppgradelabs.com and use code DAVEPOD for 15% off todayViome | Check it out at viome.com and use code 10DAVE for 10% off. It's time to stop guessing and start knowing your body.iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVETimestamps:0:00 – Intro 00:42 – Pancreatic Cancer Halted by Virus Injection 01:44 – Teens & AI Therapy Chatbots 03:13 – GLP-1 Drugs Cut Breast Cancer Risk 04:30 – Russia's $26B Longevity Program 06:18 – Sauna vs. Cold Plunge 09:10 – ClosingConnect with Dave Asprey!Website: https://daveasprey.comTikTok: https://www.tiktok.com/@daveaspreyofficialInstagram: https://www.instagram.com/dave.asprey/Facebook: https://www.facebook.com/Daveaspreyofficial/X: https://x.com/daveaspreyYouTube: https://www.youtube.com/c/daveaspreybprThe Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/Danger Coffee: https://dangercoffee.com/DAVE15Dave Asprey's BEYOND Conference: https://beyondconference.com/Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15Upgrade Labs: https://upgradelabs.com40 Years of Zen: https://40yearsofzen.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Pancreatic Cancer Halted by Virus Injection Researchers injected an engineered virus directly into pancreatic tumors in three patients — the virus replicated inside malignant cells, triggered an immune response, and stopped tumor growth and spread at an intentionally low early dose. Host Dave Asprey breaks down why oncolytic viruses can do what chemotherapy can't, how the tumor's dense biological wall becomes less of an advantage when a virus can replicate inside it directly, and why a measurable response at a safety dose is the kind of early signal that changes how he's watching this field. Sources: https://www.newscientist.com AI Chatbots and Teen Mental Health A new survey shows roughly one in five adolescents and young adults are now going to AI chatbots when they feel sad, anxious, nervous, or stressed, with usage heaviest in the 18–21 range. Host Dave Asprey explains why general-purpose language models designed to be engaging are dangerous as a substitute for real mental health support, why false reassurance from a chatbot may make the pipeline to real care harder to reach, and why this is a health systems story masquerading as a tech adoption story — and what parents need to do about it. Sources: https://www.nbcnews.com GLP-1 Drugs Cut Breast Cancer Risk Penn Medicine published a retrospective analysis of over 111,000 women finding GLP-1 exposure associated with about 35% lower odds of breast cancer in the full cohort and around 30% lower in a matched comparison group. Host Dave Asprey breaks down why this isn't just a weight loss story — it's a metabolic dysfunction story — explains the insulin resistance, inflammation, and hormonal environment mechanisms that may be driving the signal, and makes the case that this finding should be reshaping how oncologists and OBGYNs think about high-risk patients right now. Sources: https://www.pennmedicine.org Putin's $26 Billion Longevity Program The Wall Street Journal reports that Russia has made anti-aging research a Kremlin-level national priority through a $26 billion program including gene therapy, organ bioprinting, and xenotransplantation, led by Putin's daughter Maria Vorontsova and physicist Mikhail Kovalchuk. Host Dave Asprey breaks down what's geopolitical theater, what's legitimately frontier science, and why the real question is whether any findings will make it out to the broader research community or get locked inside a state program. Sources: https://www.wsj.com https://www.france24.com Sauna vs. Cold Plunge A landmark Finnish study tracked over 2,300 men for nearly 21 years and found increasing sauna frequency associated with dramatically lower cardiovascular and all-cause mortality — strongest at four or more sessions per week. Host Dave Asprey settles the debate with the actual data, explains what heat shock proteins and cold shock proteins actually are and why the evidence base behind them is nowhere near equivalent, and calls out the wellness marketing presenting early-stage mouse model research as the cold water equivalent of two decades of human mortality outcomes. Sources: https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2521522 This episode is designed for biohackers, longevity seekers, and high-performance listeners who want mechanism-level clarity on cancer treatment breakthroughs, adolescent mental health and AI, metabolic drivers of disease, geopolitical longevity science, and the real evidence behind popular recovery modalities. Host Dave Asprey connects emerging clinical research, objective epidemiological data, and real-world optimization protocols into actionable frameworks for extending healthspan, sharpening performance, and staying ahead of the science. New episodes every Tuesday, Thursday, Friday, and Sunday. Keywords: oncolytic virus pancreatic cancer, engineered virus tumor treatment, AI chatbot teen mental health, adolescent AI emotional support, GLP-1 breast cancer risk, semaglutide cancer prevention, metabolic dysfunction root cause disease, Putin longevity program Russia, New Health Preservation Technologies, anti-aging biotech geopolitics, sauna longevity mortality data, cold plunge cold shock proteins, RBM3 heat shock proteins, sauna vs cold plunge evidence, biohacking news 2026, longevity research, Dave Asprey, The Human Upgrade Thank you to our sponsors! - Suppgrade Labs | Grab your DAKE and Minerals 101 duo at shopsuppgradelabs.com and use code DAVEPOD for 15% off today - Essentia | Go to https://myessentia.com/dave and use code DAVE for $100 off The Dave Asprey Upgrade. - iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE Resources: • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Intro 00:42 – Pancreatic Cancer Halted by Virus Injection 01:44 – Teens & AI Therapy Chatbots 03:13 – GLP-1 Drugs Cut Breast Cancer Risk 04:30 – Russia's $26B Longevity Program 06:18 – Sauna vs. Cold Plunge 09:10 – Closing See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What if the key to a better sex life has nothing to do with sex itself? In this episode, I'm joined by my friend Jennifer Cohen to explore the powerful connection between wellness, confidence, fitness, and sexual health. We talk about overcoming performance anxiety, why exercise can improve desire and arousal, the role honesty plays in intimacy, and whether chemistry can actually grow over time. Plus, we answer audience questions about attraction, confidence, relationships, and the habits that help you feel your best both in and out of the bedroom. This episode is sponsored by Biologica: Head to https://biologica.com/SEXWITHEMILY to get started and get up to 32% off your first subscription order today! Take their Quick Hormonal Life Stage Quiz to find the formula that's right for you. ABOUT EMILY: Emily Morse is a Doctor of Human Sexuality, author and host of the #1 rated Sex with Emily podcast. Known as a renowned sexologist, Dr. Emily has helped millions of people around the world navigate their sex lives. Her candid and often funny conversations challenge cultural taboos, misinformation and awkward sex talks to create a future where people can deeply connect and embrace pleasure-filled lives. Because, life is too short for bad sex.  CONNECT WITH EMILY: Instagram: https://www.instagram.com/sexwithemily/  X: https://twitter.com/sexwithemily  Facebook: https://www.facebook.com/sexwithemily  TikTok: https://www.tiktok.com/@sexwithemily  Threads: https://www.threads.net/@sexwithemily CONNECT WITH JENNIFER COHEN: Instagram: https://www.instagram.com/therealjencohen/ TikTok: https://www.tiktok.com/@therealjencohen YouTube: https://www.youtube.com/@habitsandhustle Website: https://www.jennifercohen.com/  WANT MORE? Visit the Website: https://sexwithemily.com/ which includes FREE guides. Free Downloadable Guides: https://sexwithemily.com/guides/  Text With Me: https://sexwithemily.com/text  Receive Sex Tips On The Regular: https://sexwithemily.com/subscribe  Interested in 1:1 Coaching with Emily? Go to http://sexwithemily.com/coaching to apply!  Chapters: 00:00 Why Sexual Health Changes Everything 01:14 The Link Between Feeling Good & Having Better Sex 03:12 Are Sex And Intimacy Actually The Same Thing? 04:47 Why Performance Anxiety Happens In Bed 06:10 The Trick To Stop Overthinking During Sex 10:00 Why Working Out Makes Sex Better 12:03 How We Became Friends & Started Talking About Sex Nonstop 13:44 How To Tell Your Partner About Your Insecurities 16:08 How To Actually Approach Someone Without Being Weird 18:43 Masculine Energy, Feminine Energy & Dating Drama 24:42 Biohacking, Wellness & Feeling Hot Again 27:38 Vaginal Dryness, Hormones & Things Nobody Talks About 31:55 Aminos, Creatine & The Confidence Glow Up 34:00 Why Chemistry Matters more Than You Think Learn more about your ad choices. Visit megaphone.fm/adchoices

Jun 8, 2026 – Most people chasing wealth never plan for the one thing that makes it worth having: their health. In this episode of Lifetime Planning, Jim Puplava walks Cris Sheridan through his Super Longevity Protocol, a five-year project built inside his own wellness center...

Sulforaphane, Detox Pathways, and the Science of Microplastic Removal Microplastics are building up inside your brain, blood, and reproductive tissue, and most detox protocols do nothing to remove them. This episode gives you the cellular science behind why toxins accumulate, which three detox pathways control your ability to excrete them, and what the latest research shows actually moves microplastics, heavy metals, BPA, and benzene out of your body.. -Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR -For next week, 25% off all Mara Labs products when you go to www.mara-labs.com/DAVE and use code DAVE at checkout. After June 11th, the code will return to the standard 15% off. Host Dave Asprey sits down with Dr. John Gildea, a Johns Hopkins-trained PhD with 60 scientific publications and over 20 NIH-funded studies, and David Roberts, co-founder of Mara Labs and co-creator of BrocElite, the only naturally derived stable form of sulforaphane available in a capsule. Together they bring decades of research-backed biohacking and functional medicine insight into one of the most pressing longevity conversations of our time. They break down the lysosome, your cell's built-in incinerator, and explain exactly why it gets clogged with microplastics, advanced glycation end products, and other toxins that won't break down. New research shows that sulforaphane triggers a process called lysosomal surface translocation, which releases those trapped particles so your body can finally excrete them. An in-house Mara Labs study confirmed the excretion pathway: microplastics come out in feces. In the original study, the individual measured the highest microplastic levels ever recorded, and a repeat study a year later showed dramatically lower baseline microplastic levels, suggesting consistent use compounds the benefit over time. You'll Learn: Why microplastics accumulate inside lysosomes and what sulforaphane does to release them How the three detox pathways, glutathione, glucuronidation, and sulfation, work together to remove every major class of toxin What an in-house study revealed about how and where microplastics actually leave the body How toxic estrogen metabolites form and why sulforaphane is the most effective natural tool to reroute them Why berberine supports sleep optimization, ketosis, and blocks a cancer growth pathway most drugs cannot touch How sulforaphane boosts BDNF and neuroplasticity at the cellular level What microplastic sources in your home, including your dryer, rugs, and receipts, are doing to your toxin load daily Why losing weight releases stored toxins and what to take to protect your brain and metabolism during fat loss How sulforaphane activates the same AMPK longevity pathways triggered by fasting without restricting food Thank you to our sponsors! - iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE - HeartMath | Go to https://www.heartmath.com/dave to save 15% off. - Timeline | Go to timeline.com/dave and you'll get an additional 20% off your first month - Our Place | Stop cooking with toxic cookware and upgrade to Our Place today. With a 100-day risk-free trial, plus free shipping and returns, you can experience this game-changing cookware with zero risk. Visit: fromourplace.com/DAVE Use code: DAVE for 10% off sitewide Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Dr. John Gildea, David Roberts, Mara Labs, BrocElite, sulforaphane, microplastics, microplastic removal, lysosome, lysosomal surface translocation, detox pathways, glutathione, glucuronidation, sulfation, Nrf2 pathway, AMPK, TFEB1, BDNF, neuroplasticity, heavy metals, BPA, benzene, estrogen metabolism, toxic estrogen, xenoestrogens, berberine, BerbaLite, ResveraLite, c-Myc, cancer and estrogen, sleep optimization, ketosis, broccoli sprouts, isothiocyanates, PEITC, watercress, phase two detox, microplastic excretion, indoor air quality, HEPA filter, dryer lint microplastics, BPA receipts, endocrine disruptors, fat loss and toxins, autism and sulforaphane, ADHD and focus, vivid dreams and BDNF, fasting mimicry, anti-aging, biohacking, longevity, functional medicine, supplements, human performance, brain optimization, metabolism, cellular detox Resources: • For next week, 25% off all Mara Labs products when you go to www.mara-labs.com/DAVE and use code DAVE at checkout. After June 11th, the code will return to the standard 15% off. • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 0:00 – Trailer 1:55 – Intro & Context 4:48 – Microplastics & Sulforaphane 12:39 – Broccoli Sprouts Formulation 15:20 – Lab Origin Story 26:01 – Reducing Toxin Exposure 37:06 – Estrogen, Hormones & Berberine 52:46 – Autism, ADHD & Brain Health 59:01 – Wrap-Up See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Needle-Free Peptides, US Manufacturing, BPC-157, Thymosin Alpha-1, GLP-1s, Microneedle Patches, and How to Avoid Contaminated Peptides Peptides are one of the most powerful tools in biohacking and anti-aging medicine, and until now, most people couldn't access them safely, legally, or without a needle. This episode changes that. -Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR -Go to Aminoinnovations.com and use “asprey20” for a discount through the next 7 days Host Dave Asprey sits down with Justin Kirkland, a longevity medicine expert with over 30 years in drug development and pharmaceutical innovation. Kirkland holds multiple drug synthesis and formulation patents, has founded multiple pharmaceutical companies, and is one of the few people in the world manufacturing peptides entirely on US soil, controlling every step of the synthesis process from raw amino acids to finished product. If you want to understand what is really inside your peptides and why it matters for your longevity and human performance, he is the person to listen to. Dave and Justin go deep on why most peptides on the gray market contain dangerous residual compounds that can spike liver enzymes and cause real harm, why Chinese-sourced APIs are not always what they claim to be, and how a new generation of needle-free delivery systems including microneedle patches and auto-injectors is making peptide therapy accessible to anyone serious about longevity and human performance. They also cover how AI and functional medicine are converging to make peptide protocols personalized based on genetics and microbiome status, why the thymus gland is one of the most overlooked anti-aging targets in the body, and what the suppression of peptide research reveals about who really controls your access to health tools. You Will Learn: Why many gray market peptides contain toxic residual acids that damage the liver and how to identify clean products How microneedle patches and auto-injectors are replacing traditional injections for peptide delivery Which peptides are most effective for longevity, immune system repair, and human performance including BPC-157, Thymosin Alpha-1, and growth hormone secretagogues Why your genetics and gut microbiome determine whether a peptide will work for you at all How the thymus gland controls your immune system and why it disappears by your mid-20s What the suppression of peptide research tells you about Big Pharma's control over your supplement and nootropics access Why US-manufactured peptides represent a new standard for safety and quality in biohacking How AI is transforming personalized peptide protocols in functional medicine Which peptides are overhyped and which ones actually move the needle on anti-aging and recovery How to store, mix, and dose peptides correctly to avoid the mistakes most people using them are making right now Thank you to our sponsors! - Danger Coffee | Grab yours at DangerCoffee.comand use code DAVEPOD at checkout for 15% off. - The One Device | Use code DAVE for $10 off at theonedevice.com/dave - Fatty15 is on a mission to support Healthy Aging for All, including all ages and stages of life. You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com DAVE and using code DAVE at checkout. - ENERGYbits | If you want a simpler, smarter way to support your body… this is it. Head to ENERGYbits.com and use code ASPREY for 20% off your order. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Justin Kirkland, peptides, needle-free peptides, microneedle patch, BPC-157, Thymosin Alpha-1, ipamorelin, CJC-1295, PT-141, KPV peptide, Dihexa, growth hormone secretagogue, peptide purity, TFA contamination, gray market peptides, US manufactured peptides, oral peptides, transdermal delivery, thymus gland, anti-aging, biohacking, longevity, functional medicine, peptide auto-injector, compounding pharmacy Resources: • Go to Aminoinnovations.com and use “asprey20” for a discount through the next 7 days • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Intro & Guest Welcome 01:55 – Censorship & Platform Bans 06:20 – Peptide Science & Bioavailability 07:20 – Delivery Methods 14:30 – Supply Chain & US Manufacturing 17:01 – Manufacturing Risks & Contamination 24:43 – Peptide Stacks 28:41 – Immune Peptides & Thymus 30:57 – Overhyped Peptides 41:00 – Alternative Delivery (Patches, Nasal, Rectal) 47:25 – Side Effects & Risk 50:30 – Mixing & Storage Tips 54:05 – Wrap-Up & Where to Buy See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

On today's page, Chullin 33, the rabbis recommend a curious remedy for those recovering from illness, joining a long Jewish tradition of folk medicine, healing practices, and unconventional cures. From herbal concoctions and mystical amulets to remedies that sound downright bizarre to modern ears, generations of Jews searched for ways to care for body and soul alike. The daf invites us to reconsider what our ancestors were really doing when they experimented with healing. Were they merely superstitious, or were they engaged in an older form of biohacking? Listen and find out.

Join the  Uplift Community App  TODAY!    If you are in your 40s or 50s and notice your body changing faster than you expected, you are not imagining it. Most women never receive the information they need until something feels off. That is why I wanted this conversation so much. Zora Benhamou is a gerontologist with a master's degree from USC who studies aging from every angle. She hosts the Hack My Age podcast and helps women understand what is really happening in their bodies during perimenopause and menopause so they can take action with confidence. Zora is warm, direct, and honest about how research evolves. In this episode, we discuss practical biohacking tips for women over 40, strengthening bone health, balancing hormones, and boosting brain health. You'll walk away with simple daily habits and science-backed knowledge to help you age strong and feel empowered. You are going to love her.   What You'll Learn in This Episode: Why women who are "trying everything" often aren't eating enough, and how over-training and under-eating is quietly backfiring What biohacking actually means (and why it's not just for gym bros) The real story on bone health, osteopenia, and why fear is the worst response to a DEXA scan The diet approach that shows up again and again in longevity research Why GLP-1s is concern Zora has for women who don't need them The surprising blood flow restriction tool she used to maintain muscle through two hip replacements What the research actually says about cognitive decline in your 80s (it's better than you've heard) The billboard message Zora wants every woman to see about estrogen and cancer   Timestamps: (02:34) - What is biohacking, and why women need to be in this conversation (04:53) - The Harvard study on longevity and why the foundation matters more than the fancy stuff (05:14) - Alli's experience with Function Health labs and her DEXA scan at 47 (05:59) - What women are missing about bone health (and why fear is making it worse) (07:26) - The six prunes a day hack and other diet approaches for bones (07:56) - How much protein do you actually need, and the right formula for getting it in (15:25) - Under-eating, GLP-1s, and the conversation about women's bodies nobody is having loudly enough (16:17) - The Mediterranean diet and the research behind whole-food eating for longevity (18:23) - Why 1,200 calories a day was always the wrong number (19:06) - What Zora thought about aging at 35 versus now, and the research on ageism (19:26) - Cognitive decline in your 80s: the data is more hopeful than the headlines (20:41) - Crystallized vs. fluid intelligence, and why lifelong learning actually protects your brain (23:01) - The thing that surprised Zora the most in the last year (25:12) - Blood flow restriction bands: what they are, why they work, and who they're for (27:53) - OsteoStrong and biodensity machines: Zora puts the brakes on a recommendation (28:37) - The billboard every woman over 40 needs to see: estrogen does not cause cancer   Links to great things we discussed:  Hack My Age Podcast Blood Flow Restriction Bands - Katsu & Suji Zora's Movie Recommendation: F1 Zora's Book Recommendation: Nourishing Menopause Zora's Product Recommendations: Vitali Copper Peptide Skincare Collection Function Health Uplift App Wise Woman Era Alli on YouTube   I hope you loved this episode!

Dave Asprey's Beyond Biohacking event just finished. All the goss from the event right here.  Plus the new Oura Ring is out. Are the new features worth an upgrade?  PLUS The Enhanced Games, was it a success? Does it fall under biohacking? Do biohackers get unfairly lumped in with this kind of activity? Let's find out today.  Dr. Richard L. Blake, PhD, is a psychologist, breathwork researcher, and former fitness model. He holds a PhD in Transpersonal Psychology and specializes in conscious connected breathwork, mental health, and biohacking.  He frequently speaks on the intersection of science, physical performance, and holistic healing. Check out Dr. Richard L. Blake's website: www.richardlblake.com and his instagram https://www.instagram.com/the_breath_geek/  

In this thought-provoking episode of the What Are You Made Of? Show, Mike “C-Roc” sits down with Sean McCormick, Hero's Journey Coach, biohacking podcaster, consciousness explorer, health entrepreneur, and devoted family man. Sean shares his unconventional path from the corporate world to a life dedicated to personal growth, wellness, and helping high-performing men find greater purpose and alignment.Together, they dive deep into the importance of confronting life's challenges early, taking responsibility for personal development, and optimizing every area of life—from health and relationships to mindset and spirituality.Sean opens up about his recent 24-hour Ibogaine experience, offering a rare behind-the-scenes look at the powerful insights, emotional breakthroughs, and profound realizations he encountered during the journey. Sean and Mike "C-Roc" explore themes of consciousness, relationships, healing, and the pursuit of deeper self-awareness, while discussing why true fulfillment comes not from material success but from meaningful human connection. This episode is packed with wisdom on growth, self-discovery, leadership, and the courage to continually evolve into the best version of yourself.Website:https://www.seanmccormick.com/ Social Media Links/Handles:https://www.instagram.com/realseanmccormick/https://www.linkedin.com/in/seanmccormickcoaching/

I lived with severe brain fog for 15 years. I couldn't focus, my words didn't come easily, and I spent a fortune trying to fix it from the top down...little worked until I realized the problem wasn't in my head—it was in my feet.In this video, I break down the scientifically proven connection between your feet, your circulation, and your cognitive decline. We cover how your brain requires a massive 20% of your body's oxygen to function, and why sitting at a desk all day weakens the calf muscles that act as a "second heart" to pump that oxygenated blood back up to your skull. I also explain how modern cushioned shoes act as sensory deprivation chambers, muffling the critical signals your feet send to your brain. This sensory lack forces your nervous system into a constant, low-level survival state that completely kills your executive function. You don't need another brain supplement to get your mental edge back. You need to fix your foundation. I share the exact barefoot walking and foot-strengthening protocols I used to lift the fog and restore my cognitive sharpness.Thank you to our sponsors!Suppgrade Labs | Grab your DAKE and Minerals 101 duo at shopsuppgradelabs.com and use code DAVEPOD for 15% off todayEssentia | Go to https://myessentia.com/daveand use code DAVE for $100 off The Dave Asprey Upgrade.iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVETimestamps:00:00 – Personal Experience00:47 – Root Cause: Not in Your Head01:05 – Blood Flow and Brain Function02:10 – The Calf Pump03:52 – Foot Sensory Signals04:26 – Nervous System Impact06:22 – How to Fix It07:51 – Personal ResultsConnect with Dave Asprey!Website: https://daveasprey.comTikTok: https://www.tiktok.com/@daveaspreyofficialInstagram: https://www.instagram.com/dave.asprey/Facebook: https://www.facebook.com/Daveaspreyofficial/X: https://x.com/daveaspreyYouTube: https://www.youtube.com/c/daveaspreybprThe Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/Danger Coffee: https://dangercoffee.com/DAVE15Dave Asprey's BEYOND Conference: https://beyondconference.com/Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15Upgrade Labs: https://upgradelabs.com40 Years of Zen: https://40yearsofzen.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Send us Fan MailToday, I'm joined by Dr. Ezekiel Emanuel, oncologist, world-renowned bioethicist, health policy expert, and author of the new book Eat Your Ice Cream.Dr. Emanuel is the Vice Provost for Global Initiatives and University Professor at the University of Pennsylvania. He has advised the World Health Organization, helped shape the Affordable Care Act, served on the Biden-Harris COVID Advisory Board, and is the most widely cited bioethicist in history, with more than 350 publications and 16 books to his name.In a culture obsessed with biohacking, anti-aging, and optimizing every aspect of our health, Dr. Emanuel offers a refreshing, and sometimes controversial perspective. He challenges us to think differently about longevity, aging, wellness trends, and what truly creates a meaningful, healthy life.Today we're talking about the difference between living longer and living better, why relationships may matter more than supplements, and how women can navigate midlife health without getting caught up in the endless pursuit of optimization.Follow Dr Emanuel hereWebsiteNewest book: Eat Your Ice Cream! Join Move Daily MembershipFOLLOW ALONG with Move Daily Fitness!Follow on InstagramFollow on FacebookIndemnity** All information provided by Move Daily Fitness and Tracy Steen is of a general nature and is furnished for educational/entertainment purposes only. No information is to be taken as medical or other health advice pertaining to any individual's specific health conditions. Move Daily is not engaged in rendering any medical services. Move Daily makes no guarantee regarding the accuracy, timeliness or relevance of any text, video or audio content. Any content provided is not a diagnosis, treatment plan or recommendation for a particular course of action regarding your health and it is not intended to provide specific medical advice. Do not delay in seeking the advice and diagnosis of a medical professional because of anything you may have read or interpreted from Move Daily Fitness content.  Consult your health care professional before participating in or acting on any recommendations found on Move Daily Fitness.  You agree, at your exposure, to indemnify and hold Move Daily Fitness and Tracy Steen harmless from any and all losses, liabilities and injuries, or damages resulting from and all claims, cause of action, suits, proceedings and demands against Move Daily Fitness and Tracy Steen, arising from or related to decisions or recommendations you make using Move Daily Fitness content. You agree that use of this information is at your own riskIf you love total body workouts, and are looking to increase muscle, this Total Body Split Calendar (follow along video) is for you! Grab yours here today and get started.  The Move Daily Membership is a paid monthly subscription for women, which gives you access to a huge amount of resources to help support you in reaching your health goals. Whether you're looking to lose fat, gain lean muscle, focus on your nutrition, give time to wellness or simply wish to dial in your overall health, we can support you in achieving your objectives. Join today! Shop Legion Supplements and use discount code: MoveDailyThis is an affiliate link.Support the showUse discount code PODCAST10 for a discount on your Move Daily Membership. Don't fade out women, level up!Thanks for moving daily with us in your fitness, wellness and nutrition! Be sure to follow us here:YouTubeInstagramFacebookTikTokSubscribe to my podcast! 

Enhanced Games Debut in Las Vegas as the First Openly Drug-Enabled "Biohacker Olympics" The inaugural Enhanced Games took place in Las Vegas with more than 40 elite athletes competing openly while using performance-enhancing drugs, a $25 million prize pool, and a $1 million world record bonus on the table. Host Dave Asprey, who serves on the advisory board of the Enhanced Games, breaks down why this event is less a sports story than a cultural signal: enhancement has moved from underground to prime time, and the institutions that spent decades controlling that conversation through drug testing and bans watched it happen on a stage in Las Vegas. Dave explains why WADA has always existed to protect institutions rather than athletes, why bodily sovereignty is the real issue at the center of this debate, and what it means that even with full transparency about what every athlete was taking, the records didn't fall quite the way you'd expect. The Enhanced Games are the closest thing yet to a public beta test for extreme human enhancement, and the data it generates will matter far beyond sport. Sources: https://www.nytimes.com/athletic/7302319/2026/05/23/enhanced-games-athletes-world-records-doping-steroids/ https://www.npr.org/2026/05/24/nx-s1-5831252/enhanced-games-steroids-olympics-trump https://www.bbc.com/news/articles/cedpz1zqp8po https://www.wusf.org/2026-05-24/the-enhanced-games-are-sunday-heres-what-to-know-about-the-controversial-event Kyle Busch's Death Showed How Severe Pneumonia Can Rapidly Escalate Into Fatal Sepsis NASCAR driver Kyle Busch died after severe pneumonia progressed into sepsis, a condition most people hear about but few truly understand until it is too late. Host Dave Asprey breaks down the biology of what happens when the immune system stops containing an infection and starts attacking the body systemwide, why sepsis can escalate from manageable symptoms to a life-threatening emergency faster than most people expect, and why even someone with great biomarkers and a dialed-in health stack can be blindsided by an acute inflammatory crisis. The warning signs matter: worsening breathing, confusion, rapid decline, and a sense that something is badly wrong are emergency symptoms, not signals to wait and see. Longevity is not only about optimization rituals. It includes knowing when your biology is in crisis and acting before the window closes. Sources: https://www.cnn.com/2026/05/24/health/what-is-sepsis-kyle-busch-wellness https://www.cnn.com/2026/05/26/health/video/sepsis-kyle-busch-medical-care-lead-jake-tapper https://www.michiganmedicine.org/health-lab/nascar-stars-death-shows-how-sepsis-can-kill-anyone-if-not-caught https://www.huffpost.com/entry/what-is-sepsis-kyle-busch_l_6a15a9c1e4b0ddcc84641f34 Menin Loss in the Hypothalamus May Be a Central Switch That Accelerates Aging New research in mice found that a protein called Menin in the hypothalamus may function as a central coordinator of biological aging across the whole body. When Menin declined, aging accelerated. When researchers restored it in older mice, memory improved and lifespan increased. Host Dave Asprey explains why this finding challenges the dominant wear-and-tear model of aging, what it means that the hypothalamus may be running a coordinated aging program rather than simply accumulating damage over time, and why a control-room model of aging points toward fundamentally different intervention strategies than chasing downstream symptoms like fatigue and memory loss. The research connects aging to neuroinflammation, which has direct implications for how biohackers think about hypothalamic health right now. It is still animal research, but the mechanistic case is strong and the implications for longevity science are significant. Sources: https://www.sciencedaily.com/releases/2026/05/260524012959.htm https://www.news-medical.net/news/20230323/Menin-protein-protects-against-aging-and-cognitive-decline.aspx https://www.eurekalert.org/news-releases/982100 https://www.eurekalert.org/news-releases/1116021 IL-6 Blockade With Tocilizumab Showed Early Promise for Treatment-Resistant Depression A small pilot randomized trial tested tocilizumab, an anti-inflammatory drug that blocks IL-6 signaling, in people with difficult-to-treat depression and found remission rates of 54% versus 31% with placebo. Host Dave Asprey breaks down why this result reframes depression as an immune biology problem for a meaningful subset of patients rather than a purely neurochemical one, and why the same inflammatory pathway that drives joint destruction in rheumatoid arthritis is showing up in the brains of people who don't respond to antidepressants. The practical implication is not to seek out a biologic drug off-label. It is to recognize that persistent low mood, fatigue, and low resilience may warrant a deeper biological workup than standard screening provides, starting with IL-6, CRP, and a full inflammatory panel. The brain is downstream of the immune system more than most psychiatry has been willing to admit, and this trial is the clearest evidence yet of why that matters. Sources: https://www.bristol.ac.uk/news/2026/may/pilot-trial-suggests-anti.html https://www.eurekalert.org/news-releases/1128678 https://www.medicalxpress.com/news/2026-05-trial-anti-inflammatory-drug-difficult.html https://clinicaltrials.gov/ New Science Paper Says Intrinsic Human Lifespan May Be About 50% Heritable A paper published in Science argues that the genetic contribution to human lifespan is roughly 50% heritable, far higher than previous estimates, once researchers correct for deaths caused by accidents, infections, and external causes unrelated to aging biology. Host Dave Asprey explains why this finding is liberating rather than deterministic, what it means that genetics loads the dice on lifespan more than the mainstream has been willing to admit, and why personalized longevity strategy matters far more than generic population-level advice. Your genes load the dice but you still roll them. The study pushes the field toward genetic stratification and biomarker-based personalization, and it validates the core premise that the same intervention will not produce the same outcome in every person. Get your genetics tested and build your strategy from your own baseline, not from what worked for the average person in a study. Sources: https://www.science.org/doi/10.1126/science.adz1187 https://pubmed.ncbi.nlm.nih.gov/41610249/ https://www.nature.com/articles/d41586-026-00300-w https://www.eurekalert.org/news-releases/1113892 This episode is designed for biohackers, longevity seekers, and high-performance listeners who want mechanism-level clarity on human enhancement, acute inflammatory risk, neuroendocrine aging, immune-driven depression, and the genetics of lifespan. Host Dave Asprey connects emerging clinical research, real-world performance culture, and actionable optimization frameworks into a clear picture of where biology actually drives outcomes and where most people are still managing symptoms instead of finding the mechanism. New episodes every Tuesday, Thursday, Friday, and Sunday. Keywords: Enhanced Games biohacking, performance enhancement bodily autonomy, WADA elite sport doping, Kyle Busch sepsis death, pneumonia sepsis escalation, sepsis warning signs, Menin hypothalamus aging, brain aging master switch, neuroendocrine aging longevity, tocilizumab depression IL-6, inflammation treatment-resistant depression, immune biology mental health, lifespan heritability genetics, longevity genetics personalization, genetic stratification healthspan, biohacking news 2026, longevity research 2026, healthspan optimization, inflammation testing CRP IL-6 Thank you to our sponsors! - HeartMath | Go to https://www.heartmath.com/dave to save 15% off. - The One Device | Use code DAVE for $10 off at theonedevice.com/dave - iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE Resources: • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Intro 00:38 – Story 1: Enhanced Games 01:49 – Story 2: Kyle Busch Death (Sepsis) 03:09 – Story 3: Menin Protein and Brain Aging 04:37 – Story 4: Inflammation and Depression 06:20 – Story 5: Lifespan Heritability 07:47 – Takeaway See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Life hack: when you genuinely enjoy your own company and deeply respect who you are, settling stops being an option.You naturally begin to reject anything that falls below your standards — whether that's your income, career, relationships, health, or overall lifestyle. When your self-respect is strong, you simply won't tolerate experiences, environments, or people that aren't aligned with the life you truly want.In today's episode, we're diving into the importance of energetic hygiene, the beauty and wellness habits that keep me feeling my best inside and out, the systems I currently use for both maintenance and expansion in my personal life and business, how to balance the two, and so much more.So babe, pour yourself a cacao or matcha, grab your journal, and get cozy — because these hot girl habits are essential if you're serious about seeing real results.—In this episode, I discuss: 01:25 - A personal update - what life has been looking and feeling like lately04:00 - Why energetic hygiene is super important and how my daily routine looks09:50 - Not settling for anything below your standard & demanding more requires THIS18:35 - Beauty habits that keep me happy, healthy and glowing from the inside out 23:40 - The systems I have in place in both my life & biz for maintenance and expansion42:45 - What embodying my feminine has looked like recently (might be controversial)—Similar Episode: Episode 133: My metabolic age is 14, at 29?! Biohacking, slow-aging + my high-maintenance hacks to save time—My current beauty habits (checklist)Nourish (inner beauty):beef liver, electrolytes, seamoss, collagenclean protein bar in each hand and sports bagSelf-care (outer beauty):scalp oiling w rosemary oil for rootscastor oil and beeswax stick for facefragrance free products onlybeef tallow, coco oilface tapes, no botox lipgloss (clean)Nature:morning and evening sundaily grounding + being presentBody:movement - steps, gym, Pilates Whole foods only, no long ingredient list9 hours of deep sleepNervous system regulation—Connect with Laura: Laura's Website: https://www.lauraherde.com/Laura's Instagram: https://www.instagram.com/laura.herde/Laura's 1-1 Coaching: https://www.lauraherde.com/application-1-1Laura's Coaching Certification Course: https://www.instagram.com/embodiedcoachacademy/>> EMAIL ME TO CONNECT/ FOR QUESTIONS: hello@lauraherde.com>> FOLLOW ME ON INSTAGRAM FOR MORE CONTENT: @laura.herde Feel free to share this episode with your bestie, and tag us on IG when you listen so we can repost you.If you're a loyal listener and would like to support the show, leave us a rating/ review, it means the world!Make sure to be subscribed to UNFUCK YOUR LIFE, we publish episodes for you every single Tuesday.Thank you so much for tuning in, love xx

How CD38, PARP, and Leaky Gut Are Destroying Your NAD Levels | Dr. Andrew Salzman Your NAD is being drained by two hidden enzymes, your gut may be the starting point of every aging process in your body, and creatine does something to your mitochondria that has nothing to do with muscle. This episode rewrites what you thought you knew about longevity, anti-aging biology, and how your body actually produces and delivers energy at the cellular level. -Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR -Explore all of Wonderfeel's products at: getwonderfeel.com/dave They are gifting a complimentary 7-day Youngr™ supply (mini pouch) with every order across any of their products. The code will be DAVE, and the campaign will be active through June 6th. Host Dave Asprey sits down with Dr. Andrew Salzman, a physician, inventor, and biomedical entrepreneur with more than 30 years of experience in drug discovery and development. An alumnus of Harvard Medical School, Yale University, and Columbia University, Dr. Salzman has authored more than 170 scientific publications and holds 50 patents. He invented the original clinical-stage PARP-1 inhibitor, leading to the world's first clinical treatment for raising NAD levels and fighting cancers caused by the BRCA1 and BRCA2 genes. Genentech licensed his breakthrough technology for $600 million. His research into gastrointestinal microbiota, autoimmune disease, oxidative stress, and mitochondrial ATP production now forms the foundation of how millions of patients get treated worldwide. Dr. Salzman names the two biggest NAD drains in your body, CD38 and PARP, and explains why taking NMN or NR alone is like filling a bathtub with the drain wide open. He breaks down the formulation science behind pairing NAD precursors with CD38 blockers like hydroxytyrosol alongside PARP-reducing antioxidants like ergothioneine, and delivers a paradigm-shifting explanation of creatine as an energy distribution network inside your cells. Rather than a simple muscle supplement, creatine acts as a high-speed ATP shuttle that carries energy from your mitochondria to the precise location and moment your brain, gut, and heart need it most. You'll Learn: Why NAD declines with age and which two enzymes are primarily responsible for draining it How CD38 rises with inflammation rather than NAD levels, and what that means for your supplement strategy Why creatine is one of the most underrated anti-aging and brain optimization supplements available How creatine functions as a spatial and temporal energy delivery network for your brain, gut, and heart Why the gut may be the origin point of the entire aging process and how that cascade unfolds decade by decade How leaky gut drives systemic inflammation, crashes NAD, and accelerates biological aging throughout the body What controls tight junction integrity and how ATP, butyrate, creatine, and fasting all play a role Why most creatine supplements fail to absorb properly and what to look for in a high-quality source How to rebuild your microbiome in three to four weeks through diet alone, without antibiotics Why walking immediately after a meal may be doing more harm than good to your gut lining Thank you to our sponsors! - Screenfit | Get your at-home eye training program for 40% off using code DAVE at https://www.screenfit.com/dave. - KILLSwitch | If you're ready for the best sleep of your life, order now at https://www.switchsupplements.com/and use code DAVE for 20% off - Pique | Go to Piquelife.com/dave for 20% off. - iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Dr. Andrew Salzman, NAD depletion, CD38 inhibition, PARP inhibition, NMN supplements, creatine ATP shuttle, leaky gut aging, tight junction integrity, inflammaging, lipopolysaccharide gut, flagellin toxin, butyrate gut healing, ergothioneine, hydroxytyrosol, peroxynitrite, superoxide mitochondria, creatine energy distribution, gut origin of aging, NAD bathtub analogy, BRCA PARP inhibitor, Wonderfeel, creatine monohydrate, intestinal permeability, microbiome butyrate, selective digestive decontamination, TMAO nitric oxide Resources: • Explore all of Wonderfeel's products at: getwonderfeel.com/dave • Order Youngr™: getwonderfeel.com/dave• Order ChocoCreatin™: getwonderfeel.com/dave• Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 01:12 – Introduction & BRCA Background 02:19 – DNA Damage & PARP 04:38 – Free Radicals & Oxidative Stress 11:37 – NAD & Antioxidant Defense 12:34 – CD38 & NAD Depletion 23:31 – The Gut-Aging Hypothesis 30:05 – ATP, Creatine & Energy Distribution 36:41 – Creatine as Energy Shuttle 51:09 – Microbiome & Gut Repair 59:21 – TMAO & Nitric Oxide Interference 1:03:52 – Flagellin & Gut Inflammation Research 1:09:45 – FDA & Pharmaceutical Incentives 1:16:05 – Closing See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

How did we go from prophet to profit with Dr. Phil, Dr. Oz, Deepak Chopra... one by one, the curtain got lifted?  And we're left asking: who do we actually trust? Religious ethicist Dr. Liz Bucar has spent 25 years studying exactly that question. Her answers will surprise you. What you'll learn in this episode: Why the guru era is collapsing and what a good teacher actually looks like versus a predatory one The hidden Orientalism behind Deepak Chopra and Jay Shetty's appeal — and the latent racism nobody's talking about How a 19th century minister literally named after the Graham cracker gave us our food guilt Why a single question from a tarot card reader reversed years of orthorexia when therapy and church couldn't touch it What happened when a straight-edge religious studies professor did ayahuasca three times a day for three days in an Oregon yurt — and what it broke open about death, grief, and living well What sangha means and why real community requires you to be inconvenienced Prefer to watch on YouTube? https://youtu.be/5kXU5Cf2heE Resources & Links: ORDER Beyond Wellness book: https://amzn.to/4wQJypx Liz's website: https://www.lizbucar.com/books Liz's Substack (Religion, Reimagined): https://lizbucar.substack.com/ Liz on Instagram: https://www.instagram.com/lizbucar/ Liz on TikTok: https://www.tiktok.com/@lizbucar Work with Allison: https://allisonhare.com/freecall NOTABLE TIMESTAMPS 00:00 — Intro: Prophet to profit. The guru era is over. 02:25 — Welcome Dr. Liz Bucar 03:25 — Is the guru era over? Jay Shetty, Deepak Chopra, and what cracked 07:35 — The halo effect: how platform-built gurus get their power 09:23 — Red flags of a bad spiritual teacher 10:57 — What a good teacher actually looks like 11:47 — The Orientalism and latent racism behind the wellness guru industry 13:43 — What is wellness — and why it's too low of a bar 15:05 — Women, optimization, and the anemic version of human life we've been sold 16:22 — What if dying well is part of living well? 17:56 — What a "none" borrows from religion without belonging to it 21:21 — Religion's PR problem and who's controlling the narrative 24:01 — Safety, belonging, and the search for somewhere to land 25:24 — Disordered eating, orthorexia, and the tarot reading that reversed it 30:01 — How bad theology gave us food moralizing (the Graham cracker guy) 34:26 — Ayahuasca: the plan Liz did NOT have 36:58 — Santo Daime, the sacrament of Daime, and a legal ayahuasca church in the US 39:12 — Why the religious container was everything 41:53 — Confronting her father's death in an Oregon yurt 43:18 — Death doulas, dying well, and the epiphany that changed everything 44:01 — Sangha: what community actually means 45:23 — Hope vs. optimism — and why the difference matters right now 48:20 — Rage has good intel. Embrace the ugly parts. 49:05 — Why individualism has done us dirty 50:33 — Biohacking, hustle culture, and inviting friction back in 51:06 — Real community requires showing up, not just extracting 52:46 — Where to find Liz and preorder Beyond Wellness Allison's Offer: Schedule a free podcast clarity call: https://allisonhare.com/freecall Be sure to rate, review, and follow this podcast on your player and also, connect with me IRL for more goodness and life-changing stuff.Schedule a FREE podcast clarity call with me - Your future audience is out there. Talk to them!Sign up for the free weekly emailAllisonHare.comFollow me on Instagram, LinkedIn, Facebook, and YouTube.DOWNLOAD the free podcast equipment guide- No guesswork, no google rabbit holes, start recording todayReb3l Dance Fitness - Try it at home! Free month with this link.Feedback and Contact:: allison@allisonhare.com

Have you ever noticed how some people naturally feel magnetic, grounded, calm, and deeply confident without trying so hard? In this episode, I am joined with Emotional Fitness Trainer, Sam Kabert for a powerful conversation about the connection between emotional fitness, nervous system regulation, authenticity, posture, breathwork, confidence, and radiance.Together, we explore how emotional stress, emotional baggage, compartmentalization, and nervous system dysregulation can subtly shape the way we carry ourselves, interact with others, and move through life.You're going to love this conversation, and you're going to want to share it with everyone you care about who also desires to look and feel their best too!Learn more about Sam Kabert:Sam Kabert is an Emotional Fitness Trainer focused on the future of work, helping leaders regulate pressure and perform with clarity under sustained demand.Grounded in neuroscience and the 90-Second Rule, which shows that the body can complete an emotional stress response in about 90 seconds when it isn't repeatedly re-triggered by the mind. His work represents the next evolution beyond mental health, shifting from awareness and conversation to trainable, in-the-moment emotional regulation. A former Silicon Valley entrepreneur, 40 Under 40 honoree, and 3× bestselling author, Sam equips leaders and organizations to build Emotional Fitness as core infrastructure for resilience, culture, and decision-making at scale.Connect with Sam:samkabert.comJoin the Breathe Club: samkabert.com/clubStep into your Radiance Sanctuary in the Membership https://www.theschoolofradiance.com/membershipFor more resources related to today's episode, click here for the podcast episode page: https://www.theschoolofradiance.com/podcasts Follow Rachel Varga Official on Instagram: https://www.instagram.com/rachelvargaofficial/ —Catch full episodes of The School of Radiance Podcast here on YouTube https://www.youtube.com/@RachelVargaOfficial —Subscribe to the YouTube channel here: https://www.youtube.com/@RachelVargaOfficial —Follow me here:Instagram: https://www.instagram.com/rachelvargaofficial/ Facebook: https://www.instagram.com/rachelvargaofficial/ Website: https://www.theschoolofradiance.com —FREE STUFF: Download my FREE Skincare Checklist, sign up for my FREE 30 minute biohack your way to clear skin and slowing aging training now, and my newsletter for promos and exclusive events just for you! https://www.theschoolofradiance.com/freebiesEveryone gets one FREE call! Book your free 15-minute call with Rachel Varga to see which options will help you achieve your skin radiance goals! https://rachelvarga.as.me/YourPersonalizedRadianceConsultation —Looking for Skincare products, Tutorials, booking YOUR private One-on-One, and the deep dive Radiance Membership?SHOP skincare: https://alwaysradiantskinshop.comBOOK your private One-on-One: https://rachelvarga.as.me/Initialconsultation REGISTER for Tutorials and/or Membership: https://theschoolofradiance.com As a disclaimer, please note that the information shared in this podcast and interview is not to be taken as medical advice, and it's always important to consult with your physician before making any lifestyle changes. Rachel disclaims any responsibility for inaccurate credentials of guests or information used that may cause harm.Thank you for tuning in to this episode of The School of Radiance with Rachel Varga (formerly The Rachel Varga Podcast and The Always Radiant Skin Podcast)!Rachel Vargainfo@theschoolofradiance.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this thought-provoking episode of the What Are You Made Of? Show, host Mike "C-Roc" sits down with Lawrence Ellyard for a deep conversation on consciousness, wellness, intuition, and the evolving landscape of human connection. Lawrence, founder of IICT, entrepreneur, co-producer of The New Woo documentary, and author of nine books, shares his perspective on living with openness, presence, and curiosity while balancing intentionality and purpose.Together, they explore the rise of “The New Woo”, the shift of once fringe wellness and mindfulness practices into the mainstream; and discuss how meditation, somatic therapy, biohacking, energy work, and community-based healing are transforming modern wellness culture. Lawrence explains how AI and digital life are creating an even stronger desire for authentic human connection and embodied experiences.The conversation also dives into the challenges of discernment in today's wellness industry, including how to identify credible practitioners, avoid misleading marketing, and trust both intuition and verified credentials when exploring therapies, products, and modalities. Lawrence shares insights from his work with IICT, a global accreditation body representing over 1,400 wellness modalities worldwide, and discusses the importance of authenticity, integrity, and alignment in both business and personal growth.This episode is a powerful exploration of consciousness, intuition, personal development, and the future of wellness in an increasingly connected, yet disconnected world.Website: www.myiict.con https://www.instagram.com/lawrence_ellyard/

In this episode, we sit down with Nahum Vizakis—a combat veteran, elite athlete, and master healer—to explore the intersection of physical optimization and spiritual awakening. Nahum breaks down how to move past "quick-fix" wellness and into a lifestyle of radical self-responsibility, using both modern science and presence to unlock the body's full potential.Resources Mentioned:Book: The Biohacker's Guide to Spiritual Bodybuilding by Nahum VizakisMemoir: The Indigo Flame by Nahum VizakisConnect with Nahum: www.instagram.com/spiritual_bodybuilderIf this episode resonated with you:Follow the podcastShare with a mom who needs to hear thisLeave a review to help more moms find supportYou can also find me on Instagram at ⁠⁠⁠⁠@expandedmamas⁠⁠⁠⁠ for daily wellness practices and healthy habits.Want to start regulating now? Here are three short guided breathwork sessions—morning, afternoon, and night—to reset your nervous system, improve digestion, and feel more calm in just a few minutes a day. Grab it here: ⁠⁠⁠⁠THE DAILY RESET⁠⁠⁠CLEAN SWAPS for skin, home, and overall health- CLICK HEREPurchase our evening journal to start a reflective wind down routine: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Expanded Evening Journal⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Discount Codes for some of my favorites:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Genuine Essiac⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠: Click the link for 10% off your order, or use code HOPE10⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Regenalight⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠: Click the link for 10% off your order, or use code NICOLE52385FREE 30 day ⁠⁠⁠⁠⁠⁠⁠⁠⁠healthy habit reset⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

The Hidden Causes of Brain Fog, Anxiety, and Chronic Illness: Mold, Parasites, Histamine, and Low Cortisol If you're exhausted, inflamed, and can't figure out why, the answer might be hiding in your histamine, your hormones, your home, or something living inside you that your doctor will never test for. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Dr. Jessica Peatross, a former hospitalist turned functional medicine powerhouse who walked away from a conventional medical career after discovering that 90% of disease traces back to lifestyle, environment, and the toxins most doctors ignore. After graduating magna cum laude and earning her medical degree from the University of Louisville, Dr. Jess pursued training in functional medicine, nutrigenomics, and alternative therapies, and now helps thousands of patients reverse chronic illness through her KillBindSweat method and WellnessPlus app. She is also the formulator and CMO of Aegis Formulas and a leading voice at international health conferences. If chronic illness, mold toxicity, or hormonal chaos is on your radar, she is the person you want in your corner. Together, Dave and Dr. Jess go deep into the hidden drivers of mystery symptoms that functional medicine is finally starting to crack open. They cover why low cortisol is more dangerous than high cortisol, how histamine and mast cell activation syndrome explain everything from anxiety and brain fog to endometriosis and POTS, and why most "Lyme disease" is actually undiagnosed mold toxicity. They also break down the parasite epidemic hiding in plain sight across the United States, the B vitamin mistake making millions of people sicker, and why your metabolism, mitochondria, and mental health are all downstream of things your standard lab panel will never catch. This episode also gets into the real story behind Dr. Jess surrendering her California medical license rather than comply with a system she believed was working against patient health. Her firsthand account of the medical board process is something every person who cares about medical freedom needs to hear. You'll Learn: Why everyone who is chronically sick has a low cortisol awakening response and what to do about it How histamine drives anxiety, racing thoughts, palpitations, bloating, skin issues, and hormonal chaos Why 90% of people diagnosed with Lyme disease actually have toxic mold and how to test for both The parasite epidemic in the U.S. and why standard testing misses most of it How the spike protein reactivates dormant viruses and feeds the histamine loop behind long COVID Why synthetic B6 causes the very neuropathy it is supposed to fix, and what to take instead The cortisol, adrenaline, and blood pressure connection that explains "wired but tired" How progesterone stabilizes mast cells and why estrogen dominance fuels inflammation and reactivity Why Dave Asprey uses low-dose cortisol, dexamethasone, and modafinil as part of his daily performance stack The mold binders that actually work, and which popular ones can harm hypermobile people How nicotine at low doses blocks spike protein from ACE2 receptors and protects the brain What the MTHFR gene, methylation, and folic acid have to do with breast cancer, depression, and estrogen detox Thank you to our sponsors! - iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE - KILLSwitch | If you're ready for the best sleep of your life, order now at https://www.switchsupplements.com/and use code DAVE for 20% off - Calroy | Go to Calroy.com/DAVE for exclusive discounts on Arterosil HP, Vascanox HP and all Calroy products. - Cowboy Colostrum | Get your gut right by going to cowboycolostrum.com/asprey for 25% off of your entire order. -Amp | If you're ready to make fitness fit into your life, go to amp.ai to check it outDave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Dr. Jessica Peatross, functional medicine, mast cell activation syndrome, histamine intolerance, long COVID brain fog, mold toxicity, chronic Lyme disease, parasite testing, low cortisol, cortisol awakening response, MTHFR methylation, B6 toxicity, P5P, folinic acid, estrogen dominance, progesterone therapy, spike protein reactivation, Epstein-Barr reactivation, POTS, wired but tired, Kill Bind Sweat, WellnessPlus, vaccine exemptions, mold binders, nicotine ACE2, adrenal insufficiency, RCCX gene Resources: • Go to https://drjessmd.com/ and use code ‘DRJESS' at checkout • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 00:33 – Releasing Medical License 03:21 – Chronic Illness Root Causes 05:00 – Hospital Nutrition 08:11 – Dave's Health History 10:22 – Parasites 20:02 – Nicotine 23:19 – Low Blood Pressure & Minerals 28:09 – B Vitamins & Methylation 33:45 – Autism & Genetics 40:13 – Toxic Mold 43:11 – ADHD Misdiagnosis 48:27 – Histamine & Mast Cells 50:56 – Long COVID & Spike Protein 58:56 – Cortisol 1:03:56 – Lyme Disease 1:09:58 – Mold Testing & Binders 1:16:37 – Closing See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Imagina a un ser humano con inteligencia artificial añadida... sería una persona con super poderes. Eso es lo que están haciendo en China. Además escucha la burraza del día que criticaba a sus paisanos que se iban a Estados Unidos porque se quejaban y apenas llegó se dio cuenta de la dura realidad de millones de hispanos. Mantente al día con los últimos de 'El Bueno, la Mala y el Feo'. ¡Suscríbete para no perderte ningún episodio!Ayúdanos a crecer dejándonos un review ¡Tu opinión es muy importante para nosotros!¿Conoces a alguien que amaría este episodio? ¡Compárteselo por WhatsApp, por texto, por Facebook, y ayúdanos a correr la voz!Escúchanos en Uforia App, Apple Podcasts, Spotify, y el canal de YouTube de Uforia Podcasts, o donde sea que escuchas tus podcasts.'El Bueno, la Mala y el Feo' es un podcast de Uforia Podcasts, la plataforma de audio de TelevisaUnivision.

In this video, I break down the exact biological mechanisms keeping men in Okinawa, Japan, physically dominant and mentally sharp past 100. You don't need million-dollar lab work or intense weight training to reverse your biological age. Instead, these centenarians leverage five specific lifestyle protocols to naturally upgrade their biology. I explain the hard science behind how eating to 80% full shuts down the constant growth signaling that accelerates cellular aging. We'll also cover why the modern concept of retirement physically destroys your brain function within 2-3 years, and how specific social structures actually drop inflammatory chemicals in your body by up to 30%.Thank you to our sponsors!TRU KAVA | Head to trukava.com and use code DAVE10 for 10% off.Essentia | Go to https://myessentia.com/dave and use code DAVE for $100 off The Dave Asprey Upgrade.iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVETimestamps:00:00 – Intro00:47 – Okinawa's Origins01:28 – Hara Hachibu (80% Full)02:36 – Ikigai (Purpose)03:57 – Never Retire05:19 – Social Bonds (Moai)07:13 – Stress Resilience08:54 – The 5 HabitsConnect with Dave Asprey!Website: https://daveasprey.comTikTok: https://www.tiktok.com/@daveaspreyofficialInstagram: https://www.instagram.com/dave.asprey/Facebook: https://www.facebook.com/Daveaspreyofficial/X: https://x.com/daveaspreyYouTube: https://www.youtube.com/c/daveaspreybprThe Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/Danger Coffee: https://dangercoffee.com/DAVE15Dave Asprey's BEYOND Conference: https://beyondconference.com/Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15Upgrade Labs: https://upgradelabs.com40 Years of Zen: https://40yearsofzen.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In dieser Folge der Flowgrade Show spreche ich mit ADHS-Expertin Monika Ridinger über eines der meistdiskutierten Themen unserer Zeit: ADHS bei Erwachsenen.Gemeinsam tauchen wir tief in die neurologischen Hintergründe von ADHS ein und beleuchten, warum es dabei um weit mehr geht als bloße Ablenkbarkeit oder „schlechte Konzentration“. Monika erklärt verständlich, welche Hirnareale betroffen sind, warum Dopamin eine so zentrale Rolle spielt und weshalb heute immer mehr Menschen glauben, ADHS zu haben.► Außerdem geht es in dieser Folge um:* Hyperfokus & Flow-Zustände* Dopamin, Motivation & Reizüberflutung* warum ADHS oft falsch verstanden wird* den Unterschied zwischen Neurodivergenz & Krankheit* Struktur, Selbststeuerung & Prokrastination* warum manche Menschen unter Druck besser funktionieren* Medikamente, Nikotin & Biohacking* konkrete Strategien für mehr Fokus und weniger Chaos im AlltagFür mich persönlich war diese Folge unglaublich spannend, weil ich mich selbst in vielen Dingen wiedererkannt habe und gleichzeitig gelernt habe, wie wichtig eine echte Diagnose und differenzierte Betrachtung sind.Viel Spaß beim ZuhörenGo for Flow

Light Therapy, 40Hz Gamma & Brainwave Entrainment: How BrainTap Resets Sleep, Clears Brain Fog, and Boosts Productivity by 26% Your brain is being starved of the one nutrient it needs most, and it is not a supplement, not a nootropic, not a fasting protocol. It is light, and a 40 hertz flicker delivered at the right frequency can break up amyloid plaque, reset your nervous system, and get you 26 percent more productive in a single session. -Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR -Go to https://braintap.com/dave/ for an exclusive offer for The Human Upgrade listeners Host Dave Asprey sits down with Dr. Patrick Porter, PhD, award-winning author, educator, entrepreneur, and founder of BrainTap, who has spent over 35 years at the forefront of neurotechnology helping millions of people achieve mental and emotional resilience through cutting-edge brain entrainment tools. Backed by 72 peer-reviewed studies and research conducted alongside Google, Microsoft, universities in Brazil, and veteran treatment programs, Dr. Porter is one of the most experienced and validated practitioners in applied neuroscience and brain optimization working today. Together, Dave and Dr. Porter break down exactly how flickering light and binaural sound delivered through the BrainTap headset feeds the brain through the electron transport chain, triggers nitric oxide release, boosts mitochondrial energy, and drives neuroplasticity through frequency following response. They cover how 40 hertz gamma light breaks up amyloid plaque and why that same frequency is linked to reversing dementia, how BrainTap reset the circadian rhythms of coal miners in under three weeks, how 490,000 students in Brazil raised their GPA using brain wave entrainment, and how AI now builds personalized 21-day brain training protocols from 3,000 available sessions. If you are serious about biohacking your brain, upgrading sleep optimization, and doing smarter not harder work on your mind, this episode delivers the science and the tools. You'll Learn: Why light is the most underrated nutrient for brain health and how BrainTap delivers it directly to every cell in your body How 40 hertz gamma frequency breaks up amyloid plaque, restores blood flow, and may reverse dementia and Alzheimer's progression Why binaural beats and isochronic tones trigger frequency following response and what that does to your focus, metabolism, and energy How three 10-minute BrainTap sessions per day produces 26 percent more work output according to studies with Google and Microsoft How BrainTap restored deep sleep and REM cycles in coal miners with destroyed circadian rhythms in under three weeks Why 90 percent of autistic children in one study began speaking after six weeks of pulsed light therapy targeting alpha wave production How AI inside BrainTap now generates personalized brain training protocols based on your specific stress, sleep, and performance goals Why the vagus nerve is the hidden target of BrainTap's ear lights and how triggering it drives parasympathetic recovery How SMR brain waves create the optimal state for focus and concentration and why elite athletes use this for both performance and academic results What the NeuroCheck system measures across nine parameters of the nervous system in five minutes and how it validates your biohacking results Thank you to our sponsors! - AirDoctor | Go to https://airdoctorpro.com/daveasprey and save up to $300 on Air Purifiers. - AquaTru | Go to https://aquatruwater.com/daveasprey and save $100 on all AquaTru water purifiers. - iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Dr. Patrick Porter, BrainTap, brainwave entrainment, light therapy, sound therapy, binaural beats, isochronic tones, 40 hertz gamma, gamma frequency, amyloid plaque, Alzheimer's prevention, dementia reversal, neuroplasticity, brain optimization, neurotechnology, frequency following response, SMR brain waves, alpha waves, delta waves, theta waves, vagus nerve, vagal stimulation, parasympathetic nervous system, nitric oxide, mitochondria, electron transport chain, sleep optimization, circadian rhythm reset, deep sleep, REM sleep, Oura Ring, HRV, cognitive performance, focus and concentration, productivity, nootropics, brain entrainment, photobiomodulation, red light therapy, near infrared light, biohacking, human performance, anti-aging, longevity, neurohacking, mental resilience, stress reduction, anxiety relief, autism therapy, pulsed light therapy, AI personalization, personalized wellness, meditation technology, Dave Asprey, Beyond Biohacking Conference, NeuroCheck, nervous system assessment, brain health, mental performance Resources: • Go to https://braintap.com/dave/ for an exclusive offer for The Human Upgrade listeners • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 00:30 – Intro & Guest Welcome 01:45 – BrainTap: Light & the Brain 04:15 – 40Hz Gamma & Alzheimer's 05:55 – Sound & Binaural Beats 07:26 – Usage Protocol & Results 08:37 – Sleep & Circadian Reset 09:29 – AI-Personalized Sessions 10:47 – Conference Preview 12:19 – Vagus Nerve & Ear Lights 13:33 – Closing & Offer See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The ancient fruit sitting in your grocery store right now outperforms rapamycin, rivals caloric restriction, and triggers a cellular cleanup process that most longevity scientists did not even know existed until a lab changed everything 18 years ago. -Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR -Go to timeline.com/Dave or just use code ‘Dave' to get 20% off your next order. Host Dave Asprey sits down with Chris Rinsch, co-founder and President of Timeline Longevity and a PhD cell biologist who has spent nearly two decades doing pharmaceutical quality clinical research on one of the most underrated longevity molecules on earth. Before founding Timeline in 2007, Rinsch worked in venture capital investing in pioneering life sciences companies and in biotechnology developing cell-based therapies at Swiss biotech company ISOTIS SA. He has authored original publications in Nature Medicine, Nature Metabolism, JAMA Open, and Cell Reports Medicine, and holds internationally filed and granted patents on urolithin A. This is the first time a Timeline co-founder has appeared on the show. Together, Dave and Chris break down the full science of urolithin A, the postbiotic compound unlocked from pomegranate by gut bacteria, and why it triggers mitophagy to clear out damaged mitochondria and replace them with high-functioning ones. They cover why only 30 to 40 percent of people can produce urolithin A from food alone, how one month of supplementation measurably improved immune cell populations in people aged 50 to 70, and why Dave has stacked this into his daily longevity protocol alongside NAD precursors and nootropics for years. If you are serious about biohacking your mitochondria, extending healthspan, and doing smarter not harder longevity work, this episode delivers the deep science to back it up. You'll Learn: Why urolithin A outperforms rapamycin in worm lifespan studies and rivals caloric restriction at 45 percent life extension How mitophagy works, why it declines with age, and why it is one of the most important anti-aging mechanisms in the body Why eating pomegranates or taking cheap pomegranate extract does not work for most people and what to take instead How one month of MitoPure improved natural killer cells, CD8 T naive cells, and reduced inflammation in adults aged 50 to 70 Why mitochondria are central to metabolism, brain optimization, immune function, cardiovascular health, and skin aging How Timeline's topical urolithin A produced statistically significant reductions in fine lines and wrinkles after eight weeks Why Dave considers this one of the most clinically validated supplements in his longevity stack alongside NAD and fasting protocols How L'Oreal became a Timeline investor after confirming the mitochondrial science was unlike anything in their existing ingredient library What the XPRIZE Healthspan competition is targeting and why Timeline is competing to reverse biological aging by 10 to 20 years Why the future of functional medicine will require a mitochondrial blood test and how close we are to having one Thank you to our sponsors! - EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE - Calroy | Go to Calroy.com/DAVE for exclusive discounts on Arterosil HP, Vascanox HP and all Calroy products. - Neuronic | Go to www.neuronic.online Code DAVE for $100 off - ENERGYbits | If you want a simpler, smarter way to support your body… this is it. Head to ENERGYbits.com and use code ASPREY for 20% off your order. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Chris Rinsch, Timeline Longevity, MitoPure, urolithin A, mitochondria, mitophagy, pomegranate, elagitannins, postbiotic, gut microbiome, longevity, anti-aging, healthspan, biohacking, supplements, human performance, metabolism, mitochondrial health, cellular health, autophagy, natural killer cells, immune health, inflammation, NAD, rapamycin, caloric restriction, muscle endurance, collagen, skin aging, fine lines, wrinkles, topical skincare, L'Oreal, XPRIZE Healthspan, Nature Aging, clinical trials, longevity stack, brain optimization, cardiovascular health, biological age, aging clock, fasting, nootropics, functional medicine, Dave Asprey, polyphenols, microbiome diversity Resources: • Go to timeline.com/Dave or just use code ‘Dave' to get 20% off your next order. • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 00:37 – Intro 03:57 – Pomegranates 10:03 – Discovering Urolithin A & Mitophagy 20:50 – Science vs. Pomegranate Supplements 25:24 – Topical Skincare Science 26:09 – L'Oreal Partnership & Skin Results 33:38 – 15 Clinical Studies & XPRIZE 43:50 – Nature Aging Immune Study 49:22 – Dosing & Daily Routine 51:29 – Future of Mitochondrial Health See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Book a free consultation call with Robert Sikes to break through your keto or low carb plateau right here: https://www.ketobodybuilding.com/callSurviving childhood morbid obesity and a fifteen year meth addiction takes total metabolic repair. In episode 886 of the Savage Perspective Podcast, host Robert Sikes sits down with Elaina Wang to share a powerful story of survival and deep health recovery. This discussion reveals how severe insulin resistance and bad food rules created a massive drug habit just to feel energy. Getting clean from drugs was brutal, but finding the keto diet and reversing type two diabetes naturally changed her entire life. You will learn exactly how real nutrition, heavy weight lifting, and targeted peptides can heal your brain, stop cravings, and fix chronic pain after years of severe trauma and addiction.Elaina's Hack Your Health Coaching: https://hackyourhealthcoaching.com/elaina-wangElaina's FB: https://www.facebook.com/KetoWang/Get Keto Brick: https://www.ketobrick.com/Subscribe to the podcast: https://open.spotify.com/show/42cjJssghqD01bdWBxRYEg?si=1XYKmPXmR4eKw2O9gGCEuQChapters0:00 - How I Survived Childhood Obesity & Severe Insulin Resistance1:09 - Why I Started Meth: The Shocking Truth About Energy & Fatigue2:01 - The Food Pyramid Myth: How Government Guidelines Fueled Addiction3:47 - Unbreakable Confidence: How to Build Self-Esteem When Overweight6:14 - The "Fat Meth Addict": Why Stimulants Couldn't Fix Type 2 Diabetes8:17 - Meth vs Cocaine: How Drugs Hijack Brain Dopamine & Sugar Cravings11:08 - The Secret Life of a Functional Addict: Survival Tactics & Thefts13:36 - Toxic Relationships: Navigating Co-Dependency & Addiction Relapse17:03 - The Turning Point: Dodging the Cops & Deciding to Get Clean20:43 - Type 2 Diabetes Diagnosis at 24: Ignoring the Ultimate Warning Sign21:10 - Quitting Meth Cold Turkey: The Brutal Reality of Early Sobriety25:22 - Blood Sugar at 426: Why I Refused Insulin Due to Addiction Fears27:08 - Reversing Type 2 Diabetes Naturally with the Keto Diet28:24 - Keto & Neuroplasticity: The Ultimate Biohack for Addiction Recovery30:02 - Losing 80 Lbs Fast: Do Cigarettes Spike Your Blood Sugar?34:00 - Becoming a Keto Coach: The Evolution of Low-Carb & Carnivore Diets36:10 - Healing Trauma vs. Trauma Bonding: The Missing Link in Weight Loss41:17 - BPC-157 & TB-500: Can Peptides Cure Chronic Pain & Bursitis?45:13 - GLP-1 for Addiction: The Unbelievable Cure for Alcoholism & OCD49:02 - Semaglutide vs Tirzepatide: Which GLP Weight Loss Peptide is Best?51:49 - The Dark Side of Ozempic: Who Should NEVER Take GLP Peptides53:31 - 155 Lb Weight Loss Surgery: Is Medical Tourism in Tijuana Safe?57:11 - Tummy Tuck Complications: Hematomas, Wound Vacs & Honest Recovery1:01:01 - "Am I Too Old to Get Healthy?" The Ultimate Mindset Shift for Men & Women1:05:26 - Where to Find Elaina Wang: Coaching, Biohacking & Future Events

May is mental health awareness month, so I've gone back and pulled the top tips and advice from neuroscientists, psychologists and biohacking experts on how to improve your happiness, anxiety, and depression through specific supplement protocols, brain health hacks, and healing your gut. Because we can't ignore the physical side to mental health, and taking care of our bodies is a key piece in taking care of our minds.  Tune in to hear about: Our mood has EVERYTHING to do with our brain health. So what do top neuroscientists recommend for psychiatric issues? Dr. Kristen Willeumier offers her EXACT protocol for improving anxiety without a medical prescription. This is game-changing advice on the power of supplements for managing anxiety and psychiatric disorders, from an award-winning neuroscientist with a PHD and Masters in neurobiology, Masters in Physiological science, and postdoctoral scientist in the Department of Neurology at Cedars-Sinai Medical Center in LA. Your gut can play a huge role in your mental health (95% of the serotonin in our body is housed in the gut!). Clinical psychologist, author, and founder of Heartship Psychological Services, Dr. Lauren Cook, breaks down what tests and bloodwork to get, the supplements that changed her brain, and how gut health is intrinsically linked to mental health.  If you're struggling with persistent low mood and energy, this surprising supplement recommendation from chemical engineer and biohacking pro Chloe Deutscher could be the answer. Learn why certain supplements and vitamins can help with depression, calm anxiety, and boost your serotonin.   For advertising and sponsorship inquiries, please contact Frequency Podcast Network. Subscribe to my Substack:teachmehowtoadult.substack.comFollow us on the ‘gram:@teachmehowtoadultmedia@gillian.bernerFollow on TikTok: @teachmehowtoadultSubscribe on YouTube

Your relationships are reshaping your biology in ways that diet and exercise alone cannot fix, and the science behind it will change how you think about longevity, metabolism, and what it actually means to be healthy. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Dr. Molly Maloof, a physician and one of the most innovative voices in personalized medicine, functional medicine, and human performance. Since 2012, she has advised or consulted for over 50 companies across digital health, consumer health, and biotechnology. She pioneered a course on healthspan at Stanford University and founded Adamo Bioscience, a company dedicated to unlocking the science of love as a pathway to healing and human connection. Dr. Maloof brings a rare combination of clinical depth, biohacking credibility, and entrepreneurial range to one of the most overlooked conversations in longevity. Together, Dave and Dr. Maloof dig into the neurobiology of love and attachment, the hormonal drivers of the sex drive and pair bonding, and how chronic isolation wrecks your metabolism at the cellular level. They explore the cell danger response and how toxic relationships, mold exposure, and trauma can lock your cells into a self-protection mode that blocks healing. They also cover psychedelics as hormetic tools, oxytocin as nature's medicine, the placebo response, peptide therapy for mitochondrial repair and anti-aging, and why regenerative medicine is about to rewrite the rules of human lifespan. If you are serious about biohacking your body from the inside out, this episode is essential. You'll Learn: Why human connection is a biological necessity, not a lifestyle preference, and what isolation does to your mitochondria and metabolism How the three neurobiological drives of sex, romantic love, and attachment are wired into your hormones and what happens when they go wrong What the cell danger response is, why it gets stuck, and which peptides, supplements, and therapies help break the cycle How oxytocin drives wound healing, immune function, and the placebo response Why psychedelics work as hormetic love drugs and how they reproduce the neurobiology of romantic love The top peptides for mitochondrial repair, brain optimization, and telomere biology Why Dave and Dr. Maloof believe we have already reached longevity escape velocity How AI is accelerating precision medicine, protein folding breakthroughs, and the future of anti-aging therapeutics Why fasting, breathwork, neurofeedback, and somatic therapies all converge on the same biological reset mechanism How to build the adaptive capacity and bioenergetic reserves to bounce back from anything Thank you to our sponsors! - Danger Coffee | Grab yours at DangerCoffee.com and use code DAVEPOD at checkout for 15% off. - Amp | If you're ready to make fitness fit into your life, go to amp.ai to check it out - Puori | Go to Puori.com/DAVE or use code DAVE at checkout to get 32% off your Puori Fish Oil subscription. You save more than $18 - Our Place | Stop cooking with toxic cookware and upgrade to Our Place today. With a 100-day risk-free trial, plus free shipping and returns, you can experience this game-changing cookware with zero risk. Visit: fromourplace.com/DAVE Use code: DAVE for 10% off sitewide Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Dr. Molly Maloof, Adamo Bioscience, Stanford University, personalized medicine, functional medicine, healthspan, longevity, biohacking, human performance, anti-aging, regenerative medicine, longevity escape velocity, cell danger response, mitochondria, mitochondrial health, oxytocin, vasopressin, dopamine, serotonin, neurobiology of love, attachment theory, pair bonding, sex drive, hormone replacement therapy, testosterone, estrogen, menopause, andropause, libido, female sexual dysfunction, relationship biology, social health, isolation, community, co-regulation, trauma healing, psychedelics, MDMA, psilocybin, ibogaine, ayahuasca, hormetic stress, social hormesis, neurofeedback, 40 Years of Zen, breathwork, nervous system regulation, HPA axis, cortisol, mast cell activation, histamine, long COVID, mold exposure, phospholipid therapy, glutathione, vitamin C, BPC-157, TB500, SS31, epothilone, SELANK, SEMAX, BDNF, telomere biology, telomerase, peptides, GLP-1, placebo response, wound healing, metabolism, continuous glucose monitoring, gut health, AI, precision medicine, supplements, brain optimization, neuroplasticity Resources: • Grab Molly's Book The Spark Factor: https://www.amazon.com/Spark-Factor-Supercharging-Optimizing-Feeling/dp/0063207206 • Learn More About Dr. Molly's Work: https://drmolly.co/ • Visit Your Healthspan Journey: https://yourhealthspanjourney.mystrikingly.com/ • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 00:28 – Intro 01:39 – COVID Isolation & Its Effects 03:11 – Science of Love & Hormones 04:24 – Psychedelics & Love Chemistry 09:22 – Cell Danger Response 11:07 – AI, Tech & Human Connection 13:20 – Social Connection as Medicine 20:50 – Placebo, Care & Psychedelics 24:49 – Altered States & Healing Modalities 30:09 – Peptides & Longevity Drugs 35:44 – Mast Cell & Personal Health Challenges 43:46 – Regenerative Medicine & The Future 46:17 – Longevity Escape Velocity 50:05 – Outro See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What happens when a world-famous chef starts questioning the food system, modern wellness culture, and the way we've been taught to think about health?   In this rerun episode of BS Free MD, Drs. May and Tim Hindmarsh sit down with Australian chef, author, and wellness advocate Pete Evans for a conversation that goes far beyond recipes and nutrition trends. Pete shares how his journey from professional surfer to celebrity chef eventually led him toward a deeper exploration of healing, intentional living, and the emotional connection people have with food.   The discussion dives into the power of real, minimally processed ingredients, the importance of reconnecting with cooking at home, and why food may play a larger role in overall wellness than many people realize. Pete also reflects on the cultural and spiritual side of eating — from slowing down and sharing meals to questioning the systems that shape modern health advice.   This episode is less about rigid diet rules and more about curiosity, awareness, and reclaiming a healthier relationship with what we put into our bodies.   In This Episode Pete Evans' evolution from celebrity chef to wellness advocate Why real food and cooking at home matter more than ever The connection between food, community, and emotional well-being How modern lifestyles may be disconnecting people from health The role of intentional living and mindful eating Why questioning mainstream narratives became part of Pete's journey Thoughts on healing, simplicity, and returning to foundational habits   About Pete Evans Pete Evans is an Australian chef, restaurateur, cookbook author, and television personality known for his focus on whole foods, wellness, and lifestyle-centered health approaches. Over the years, he has become a prominent voice in conversations around nutrition, cooking, and alternative health philosophies. He is also associated with the documentary The Magic Pill, which explored dietary approaches to chronic disease and metabolic health.   Welcome to BS Free MD — the podcast where medicine, freedom, family, culture, and curiosity collide. Hosted by Dr. May Hindmarsh and Dr. Tim Hindmarsh, BS Free MD is known for having bold, unfiltered conversations that challenge conventional thinking in healthcare and beyond. From wellness and medical freedom to culture, science, parenting, and current events, the show explores topics many people are thinking about — but few are willing to openly discuss. With a mix of humor, honesty, skepticism, and humanity, May and Tim bring on physicians, scientists, authors, advocates, and thought leaders for conversations designed to help listeners think critically, ask better questions, and live more intentionally. Whether you agree, disagree, or land somewhere in the middle, BS Free MD invites listeners into thoughtful dialogue without the corporate filter. Listen & Follow BS Free MD

In this episode of Beyond The Pain, I'm joined by Eric Headlee, who shares his remarkable journey from a catastrophic knee injury to exploring holistic health, biohacking, stem cell therapy, and longevity practices.Eric opens up about how injury, pain, and declining health led him to question the limitations of conventional approaches and search for deeper answers. We discuss his experience with reversing liver fibrosis, the role of stem cell therapy in recovery, and how mental, emotional, and physical health all interact when it comes to chronic pain.This conversation explores why pain is rarely just a mechanical issue, how trauma and emotional stress can influence the body, and why people dealing with persistent pain may need to look beyond symptom management if they want long-term change.We discuss:Eric's personal injury and recovery journeyThe limitations of traditional medicineBiohacking and reversing liver fibrosisStem cell therapy versus surgeryThe impact of mental health on physical painTrauma, emotional health, and chronic painLongevity practices and future health optimisationContact Eric:www.ariseelitelongevity.comwww.thearisemethods.comContact Leigh:Beyond The Pain book Free Chapter - https://bodychek.co.uk/book-waitlist/Beyond The Pain 14-Day Programme - https://bodychek.co.uk/beyond-the-pain-programme/Pain-Free Plate Free Guide - https://www.bodychek.co.uk/freepainguide/Consult with Leigh - https://www.bodychek.co.uk/consultation

Most guys over 40 rely on coffee just to survive the day, completely unaware that they are pushing their brains into a frantic, high-stress state that actually destroys deep focus and accelerates cognitive decline. In this video, I reveal the science behind why caffeine is failing you and introduce you to a 4,000-year-old amino acid used by monks to achieve effortless, sustained attention. I'll walk you through the optimal 2:1 biohacking stack that flips your coffee from a nervous, jittery habit into a highly controlled focus weapon. You'll learn exactly how to dose it, when to take it, and how to stop the hidden lifestyle habits that are secretly sabotaging your nervous system, so you can reclaim the mental edge you had in your twenties and stay competitive.Thank you to our sponsors!-HeartMath | Go to https://www.heartmath.com/dave to save 15% off-The One Device | Use code DAVE for $10 off at theonedevice.com/dave-iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVETimestamps:00:00 – Intro00:21 – Background & Credentials01:28 – How Caffeine Works03:01 – Alpha vs Beta Brainwaves04:06 – The Focus Amino Acid04:55 – What Is L-Theanine05:35 – Quality & Common Mistakes06:51 – Building the Stack08:37 – Lifestyle Foundations10:36 – Rules & GuidelinesConnect with Dave Asprey!Website: https://daveasprey.comTikTok: https://www.tiktok.com/@daveaspreyofficialInstagram: https://www.instagram.com/dave.asprey/Facebook: https://www.facebook.com/Daveaspreyofficial/X: https://x.com/daveaspreyYouTube: https://www.youtube.com/c/daveaspreybprThe Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/Danger Coffee: https://dangercoffee.com/DAVE15Dave Asprey's BEYOND Conference: https://beyondconference.com/Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15Upgrade Labs: https://upgradelabs.com40 Years of Zen: https://40yearsofzen.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Nick from Nicole Rejects returns with another mind-rattling deep dive into chemical imbalances, detoxification, retinal perception, and the possibility that light itself bends the reality around us. From toxins and frequency to the hidden science behind human vision, this episode hits different. Tune in, lock in, and #lookItUp.THE OCCULT REJECTSSTAND WITH CHEF AND HIS WIFE AGAINST  KIDNEY FAILUREBUY THE LIMINAL TREES BOOK NOW ☂️☂️☂️ALERT OPERATIONS: CRYPTID WARFARE GET CLEAN: DETOX AND MAKE KIDS HEALTHY AGAIN// // GET 15% OFF AT CHECK OUT USING "PARANOI" at FLAVORS OF THE FORESTTHE TREBLES SHOW

Welcome to PGX Ideas.PGX Ideas is where I sit with people who think for a living — scientists, philosophers, builders, and the occasional genius who doesn't fit any category.These conversations are dense. They're long. They won't give you a shortcut.If you're looking for something light, that's PGX: Raw & Real → https://www.youtube.com/playlist?list=PLa6DgTttATAc0hftp0aZtUvCgVSKO8hbxIn this episode, I spoke to  @timferriss  Author, Investor and Host of The Tim Ferriss Show.Timestamps:00:00 — Life Is a Game You Get to Design13:10 — AI Won't Save You30:11 — The Golden Age of Medicine43:21 — India's Biggest Bet52:26 — Know Your Direction First 01:15:53 — Why Tim Quit Social Media01:23:16 — The Longevity Lie01:50:47 — What Scares Tim FerrissEnjoy.— Prakhar

One Creatine Dose Kept Sleep-Deprived Brains 12% Sharper A randomized, double-blind crossover trial kept 29 healthy adults awake for 21 hours straight ... half the time on a single moderate dose of creatine (~14g), half the time on placebo ... and found the creatine group held on to up to 12% more cognitive performance across logic, reaction time, and language processing. Host Dave Asprey breaks down why sleep deprivation is just another form of brain energy stress, how creatine's phosphate-buffering mechanism stabilizes ATP in the prefrontal cortex under pressure, and why this changes how he thinks about red-eye flights and all-nighters. Vegetarians and women showed the largest effects ... your baseline diet sets your ceiling. Sources: https://pubmed.ncbi.nlm.nih.gov/42075005/ https://www.nutraingredients.com/Article/2026/04/21/single-dose-creatine-may-support-cognition-in-sleep-deprivation-study/ https://pmc.ncbi.nlm.nih.gov/articles/PMC10902318/ https://medicalxpress.com/news/2024-04-creatine-cognitive-deprivation.html Your Gum Is Dosing You With Thousands of Microplastics A pilot study tested 10 commercial gums ... five synthetic, five marketed as natural or plastic-free ... and found every single one shed hundreds to roughly 3,000 microplastic fragments per stick into saliva, with no meaningful difference between synthetic and "natural" varieties. Host Dave Asprey connects this to total toxic load management, explains why "natural" label claims mean nothing without polymer-free verification, and makes the case that even innocent daily habits contribute to the cumulative plastic burden most people aren't tracking. The takeaway isn't panic ... it's precision. Sources: https://www.acs.org/pressroom/presspacs/2025/march/chewing-gum-can-shed-microplastics-into-saliva-pilot-study-finds.html https://www.sciencedirect.com/science/article/pii/S2666911025000243 https://samueli.ucla.edu/bursting-your-bubble-chewing-gum-releases-microplastics-into-your-saliva-ucla-research-shows/ https://www.food-safety.com/articles/10285-study-shows-chewing-gum-releases-thousands-of-microplastics-whether-gum-is-synthetic-or-natural Irregular Bedtimes in Your 40s May Double Heart Attack Risk Finnish researchers followed 3,231 people from age 46 using objective accelerometer data and tracked cardiovascular outcomes for a decade ... finding that people with highly irregular bedtimes, especially combined with short sleep, had roughly double the risk of major cardiovascular events compared to those with consistent sleep timing. Host Dave Asprey explains why your vascular biology runs on a precise circadian schedule, why ambitious, otherwise-healthy people are most at risk of ignoring this lever, and why a 90-minute bedtime window ... protected even on weekends ... may be one of the cheapest cardiovascular interventions available. It'snot just how much you sleep. It's when. Sources: https://www.sciencedaily.com/releases/2026/05/260504154026.htm https://hsph.harvard.edu/topic/aging/ Scientists Decode the Plant Molecule That Kills Cancer Cells in the Lab UBC researchers published a chromosome-level genome map of Mitragyna parvifolia ... a kratom relative ... and used it to decode the full biosynthetic pathway for mitraphylline, a rare alkaloid that has shown real anti-tumor activity in cell and animal models but has never been producible at clinical scale. Host Dave Asprey explains why this is the same early chapter that vincristine and paclitaxel were in before becoming mainstream chemotherapy, draws a hard line between this pipeline story and influencer narratives about kratom as a cancer treatment, and breaks down what it actually means when researchers crack a plant's genetic recipe for a bioactive compound. Nature has been solving cancer for millions of years... we're finally learning to read it. Sources: https://academic.oup.com/plcell/article/37/9/koaf207/8237526 https://www.sciencedaily.com/releases/2026/05/260512213836.htm https://news.ok.ubc.ca/2025/10/14/researchers-reveal-how-plants-make-anti-tumour-drugs/ https://pmc.ncbi.nlm.nih.gov/articles/PMC12217235/ Scientists Built an On/Off Switch for Sperm Production — No Hormones Cornell researchers used a small-molecule inhibitor called JQ1 to pharmacologically shut down sperm production in male mice for the duration of treatment, then stopped the drug and watched full fertility restore... with healthy offspring and no detectable genomic damage. Host Dave Asprey breaks down the BRDT mechanism that makes this work without touching testosterone or hormones, explains why this is a proof-of-concept rather than a near-market drug, and outlines the questions that need answering before this moves to humans: long-term testicular health, epigenetic marks in recovered sperm, and mood and testosterone interaction over time. The era of precision male reproductive biology is just beginning. Sources: https://pubmed.ncbi.nlm.nih.gov/41945432/ https://www.sciencedaily.com/releases/2026/04/260407193844.htm https://www.news-medical.net/news/20260407/Study-advances-safe-reversible-male-contraceptive-without-hormones.aspx https://www.independent.co.uk/news/science/breakthrough-male-birth-control-sperm-b2972841.html This episode is designed for biohackers, longevity seekers, and high-performance listeners who want mechanism-level clarity on cognitive performance, toxic load management, circadian biology, plant-derived drug discovery, and the future of male reproductive medicine. Host Dave Asprey connects emerging clinical research, objective epidemiological data, and real-world optimization protocols into actionable frameworks for extending healthspan, sharpening performance, and staying ahead of the science. New episodes every Tuesday, Thursday, Friday, and Sunday. Keywords: creatine sleep deprivation cognition, brain energy ATP creatine, microplastics chewing gum, natural gum microplastics, toxic load biohacking, irregular bedtime heart attack risk, circadian rhythm cardiovascular, sleep timing heart health, mitraphylline cancer compound, kratom plant alkaloid drug discovery, oncolytic plant molecule, male birth control non-hormonal, sperm production reversible, BRDT JQ1 contraception, biohacking news 2026, longevity research, performance optimization, healthspanextension Thank you to our sponsors! - KILLSwitch | If you're ready for the best sleep of your life, order now at https://www.switchsupplements.com/and use code DAVE for 20% off - ALP | Head to http://alppouch.com/ and use code DAVE for 20% off your first order - iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE Resources: • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Intro 00:36 – Fluoride Correction 01:14 – Story 1: Creatine & Sleep Deprivation 03:21 – Story 2: Microplastics in Gum 04:53 – Story 3: Irregular Bedtimes & Heart Risk 06:31 – Story 4: Kratom Plant & Cancer Research 08:18 – Story 5: Male Contraception On/Off Switch 10:02 – Wrap-Up See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

If you're over 50 and still doing cardio to stay healthy, you're wasting your time and may actually be making things worse. This episode breaks down the exact movements, supplements, and anti-aging strategies that build real strength, protect your bones, and extend your longevity without spending hours in the gym. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Will Harlow, a master's-level physiotherapist and founder of HT Physio, whose YouTube channel has amassed over 1.5 million subscribers by teaching people over 50 how to stay mobile, active, and independent without painkillers or surgery. Will graduated with a first-class degree from Brunel University, trained in both the NHS and professional sport, and has spent his career proving that what most doctors call "just aging" is actually optional. Together, Dave and Will dismantle the myths keeping older adults weak, injured, and overtrained. They get into why resistance training beats cardio for human performance and metabolism at every age, how anabolic resistance changes your protein needs after 50, which three compound movements deliver the biggest functional gains, and why your grip strength may be the most underrated biomarker you're ignoring. Dave also shares how he used biohacking, targeted supplements, and functional medicine principles to grow bones so dense his surgeon couldn't cut through them. They also dig into vestibular training, hydration, magnesium, Vitamin DAKE, and how tools like AI are now helping people identify movement problems before they become joint replacements. This is essential listening for anyone serious about longevity, anti-aging, biohacking, sleep optimization, supplements, smarter not harder training, human performance, and building a body that performs decades past its expiration date. You'll Learn: Why chronic cardio decreases bone density and muscle mass in people over 50 The 3-2-1 resistance training method that delivers 80% of results in 40 minutes a week How anabolic resistance changes protein requirements as you age and what to do about it The three compound movements every person over 50 should master first Why grip strength predicts overall health and how to train it How vestibular disorders silently destroy balance and confidence, and how to reverse them The supplement stack (Vitamin DAKE, magnesium glycinate, digestive enzymes) that supports bone, muscle, and metabolism Why 7,000 steps beats 10,000, and where that number actually came from How Dave used biohacking and functional medicine to grow bones that broke a surgeon's saw Why AI tools can now spot gait problems that lead to hip replacements years later Thank you to our sponsors! - Active Skin Repair | Get 25% off your order until May 21, after that, it drops back to 20%, visit ActiveSkinRepair.com and use code DAVE. You can also find Active Skin Repair on Amazon and at your local CVS - Danger Coffee | Grab yours at DangerCoffee.com and use code DAVEPOD at checkout for 15% off. - Neuronic | Go to www.neuronic.online Code DAVE for $100 off - Quantum Upgrade | Go to QuantumUpgrade.io/DAVE to claim your 15-day free trial - fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Will Harlow, HT Physio, Independence for Life, physiotherapy, physical therapy, over 50 fitness, resistance training, strength training, muscle mass, bone density, osteoporosis, goblet squat, Romanian deadlift, farmer's carry, compound movements, progressive overload, 3-2-1 method, exercise snacks, balance training, vestibular health, vestibular disorders, fall prevention, hip fracture, anabolic resistance, protein intake, muscle protein synthesis, grip strength, zone 2 cardio, overtraining, sarcopenia, frailty, mobility, functional movement, gait analysis, fascia, inflammaging, NLRP3, EGCG, green tea extract, luteolin, shockwave therapy, digestive enzymes, betaine HCL, stomach acid, magnesium glycinate, Vitamin K2, Vitamin DAKE, zinc, calcium, electrolytes, cortisol, testosterone, anti-aging, longevity, biohacking, supplements, human performance, metabolism, AI, Dave Asprey, 7000 steps, 10000 steps, pedometer, body weight training, resistance bands, home workout, senior fitness, healthy aging, biological age, heart rate variability, VO2 max, morning stiffness, hip pain, knee pain, back pain, fascia hydration, infant reflexes, vestibular training, eye tracking, sit to stand, bone density surgery, dense bones, UK healthcare, NHS, healthcare system Resources: • Preorder Will's Upcoming Book Independence for Life (5/26) at: https://www.penguinrandomhouse.com/books/804636/independence-for-life-by-will-harlow/ • Learn More About Will's Work: https://willharlow.com/ • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 00:36 – Intro 02:59 – Why Resistance Training Matters 03:38 – US vs. UK Health Culture 06:15 – Getting Started with Resistance Training 07:12 – Top 3 Movements Over 50 10:30 – Hip Mobility & Inflammation 12:19 – Hydration, Joints & Electrolytes 14:11 – Balance, Falls & Exercise Snacks 15:21 – Biological Age & Longevity 16:41 – Biohacking vs. Optimization 20:08 – Overtraining & the 3-2-1 Method 29:42 – Protein & Anabolic Resistance 33:57 – Energy, Fat & Cortisol 37:49 – Vestibular Health & Balance 50:07 – Gait & Movement Rehab 56:56 – Steps, VO2 Max & Wearables 57:25 – Book Promo 01:02:14 – 7,000 Steps 01:04:22 – Wrap-Up See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Most people think jet lag is just about time zones. What if the real problem is inflammation? In this episode of Get Yourself Optimized, I sat down with Andrew Herr, founder and CEO of FlyKitt, a former human performance strategist for the U.S. military, and twice named a Mad Scientist by the U.S. Army, and he completely reframes how you think about travel, recovery, and peak performance. "When your body runs cleaner, when it's being more efficient, when it's not inflamed, you can just catch the signal better." Andrew doesn't just help road warriors arrive feeling sharp. He goes deep on the physiology of sleep, the underrated power of polyphenols, the psychological tools that break self-sabotage, and the surprising spiritual dimension of optimizing your health. In this episode, we cover:

Mental health is the silent price many entrepreneurs pay for chasing success. Dr. John Delony spent years letting stress and anxiety take a toll on his health, relationships, and personal life. But when the pressure piled on, he finally chose to confront what his body had been signaling all along. Through therapy, radical honesty, and intentional daily habits, he rebuilt life around peace over performance. In this episode of the Mental Wealth Series, Dr. John shares six daily choices entrepreneurs can use to quiet anxiety, beat burnout, and stop outsourcing their self-worth to achievements.  In this episode, Hala and Dr. John will discuss:  (00:00) Introduction (03:19) Burning Out While Chasing Success (08:31) Masculinity Crisis and the Loneliness Epidemic (15:20) Redefining Anxiety and Mental Health Labels (20:41) The Truth About Mental Health Medications (27:17) How to Become a Safe, Peaceful Presence (32:33) Six Daily Choices for a Non-Anxious Life (48:47) The Importance of Decluttering Your Environment (53:39) Why Real Human Connection Beats AI Therapy (1:00:34) Building an Authentic Personal Brand That Lasts  Dr. John Delony is a bestselling author, mental health expert, and host of The Dr. John Delony Show. With two PhDs in counseling and higher education, he has spent over two decades in crisis response and leadership. Now at Ramsey Solutions, John helps people reclaim their mental health, build deep relationships, and live non-anxious lives. Sponsored By: Huel - Get over $50 in savings with the Discovery Bundle from Huel. Use my exclusive code YAP15 for 15% off at huel.com/yap15. Indeed - Get a $75 sponsored job credit to boost your job's visibility at Indeed.com/profiting Shopify - Start your $1/month trial at Shopify.com/profiting. Quo - Run your business communications the smart way. Try Quo for free, plus get 20% off your first 6 months when you go to quo.com/profiting Fabric - Protect your family with term life insurance from Fabric by Gerber Life. Apply today in just minutes at meetfabric.com/profiting  ZocDoc - Stop putting off those doctors' appointments. Find and instantly book a doctor you love today at Zocdoc.com/PROFITING  Blinkist - Turn the world's best nonfiction books into quick 15-minute reads or listens. Grab your free trial plus an exclusive 30% discount at blinkist.com/profiting   Remitly - Transfer money internationally with Remitly, with no hidden fees. Use code BUSINESS to get a $100 bonus after you send $300 or more. New customers only.  Prolon - Reset and rejuvenate your body with Prolon's five-day plant-based fasting mimicking program. Go to ProlonLife.com/PROFITING for 15% off sitewide plus a $40 bonus gift when you subscribe to their 5-Day Program. Resources Mentioned: Dr. John's Podcast, The Dr. John Delony Show: bit.ly/TDJDS-apple  Dr. John's Book, Building a Non-Anxious Life: bit.ly/JD-BANAL  Dr. John's YouTube: youtube.com/@TheDrJohnDelonyShow  Dr. John's Website: johndelony.com  Dr. John's Instagram: instagram.com/johndelony  YAP E362 with Dr. Caroline Leaf: youngandprofiting.co/MentalWellness  Mental Wealth Series E1: Active Deals - youngandprofiting.com/deals  Key YAP Links Reviews - ratethispodcast.com/yap YouTube - youtube.com/c/YoungandProfiting Newsletter - youngandprofiting.co/newsletter  LinkedIn - linkedin.com/in/htaha/ Instagram - instagram.com/yapwithhala/ Social + Podcast Services: yapmedia.com Transcripts - youngandprofiting.com/episodes-new  Entrepreneurship, Entrepreneurship Podcast, Business, Business Podcast, Self Improvement, Self-Improvement, Personal Development, Starting a Business, Strategy, Investing, Sales, Selling, Psychology, Productivity, Entrepreneurs, AI, Artificial Intelligence, Technology, Marketing, Negotiation, Money, Finance, Side Hustle, Startup, Mental Health, Career, Leadership, Mindset, Health, Growth Mindset, Wellness, Biohacking, Motivation, Manifestation, Brain Health, Life Balance, Self-Healing, Positivity, Happiness, Sleep, Diet

The person you love is either raising your hormones or destroying them, and most people have no idea which one is happening to them. John Gray, the author of one of the most beloved relationship books of all time, returns to reveal how your relational environment directly shapes your biology, and what you can do right now to hack it. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR John Gray wrote Men Are from Mars, Women Are from Venus, the number one bestselling book of the entire decade and one of USA Today's top 10 most influential books of the last quarter century. His books have been translated into 45 languages across more than 100 countries. But what most people miss is that Gray is also a pioneer in the intersection of hormonal health, brain optimization, and human performance, a biohacker before the word existed. His newest book, Men Are from Mars for Women Only: Be Happy With or Without a Man, is the first in a six-part series packed with cutting-edge insights on relationships, biology, and longevity. Host Dave Asprey and John Gray go deep on the hormonal mechanics of desire, attraction, and emotional regulation, covering why societal testosterone collapse is driving relationship breakdown, how estrogen and testosterone function as a polarity system in both men and women, and why the relational environment you create every day is either building or destroying your biological potential. They also cover lithium orotate as a brain optimization supplement, the anti-aging power of semen retention, pre-digested protein as a nootropics-adjacent tool for brain healing, and how fasting and discipline directly boost testosterone. Gray even shares how he reversed early-stage Parkinson's using biohacking techniques and now maintains a testosterone level of 600 at age 74, with zero pharmaceutical support. This is essential listening for anyone serious about biohacking, longevity, anti-aging, supplements, human performance, brain optimization, functional medicine, metabolism, and hacking the biology of love and attraction. You'll Learn: Why testosterone collapse is the hidden driver behind modern relationship failure How your partner's emotional state directly affects your hormones in real time The prolactin trap that kills sexual desire in long-term relationships and how to escape it Why lithium orotate is one of the most underrated supplements for dopamine and serotonin balance How mirror neurons open and close based on stress, and what that means for emotional connection The five-finger ask technique that raises estrogen and testosterone simultaneously How pre-digesting protein with enzymes achieves 93 percent assimilation and supports brain repair Why fasting, discipline, and semen retention are among the most powerful testosterone-building tools available Thank you to our sponsors! - Active Skin Repair | Get 25% off your order until May 21, after that, it drops back to 20%, visit ActiveSkinRepair.com and use code DAVE. You can also find Active Skin Repair on Amazon and at your local CVS - iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE - Amp | If you're ready to make fitness fit into your life, go to amp.ai to check it out - Igniton | Try risk free at Igniton.com and use code DAVE at checkout for 15% off. Backed by a 30-day money back guarantee. - Pique | Go to Piquelife.com/dave for 20% offDave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: John Gray, Men Are from Mars Women Are from Venus, testosterone, estrogen, hormonal health, hormone optimization, prolactin, oxytocin, dopamine, serotonin, lithium orotate, mirror neurons, longevity, anti-aging, biohacking, supplements, fasting, semen retention, NoFap, multi-orgasmic men, sexual health, libido, foreplay, relationship advice, men and women, emotional regulation, stress hormones, cortisol, adrenaline, epigenetics, Parkinson's disease, protein assimilation, digestive enzymes, pre-digested protein, whey protein, casein protein, Mars Venus app, five finger ask, Venus talk, emotional processing, trauma, post traumatic stress, testosterone collapse, relationship breakdown, attraction, desire, masculine feminine polarity, Dave Asprey, 40 Years of Zen, hormones and behavior, relational biology, conscious relationships, mirror neurons and sex, luteinizing hormone, monk celibacy, meditation Resources: • Grab All Of John's Books And Content At: https://www.marsvenus.com/ • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 00:45 – Intro 02:23 – Testosterone & Relationship Collapse 02:41 – Hormones & Stress 08:37 – Attraction & Sexual Polarity 10:36 – Communication & Conflict 20:21 – Emotions & Trauma 21:27 – Mirror Neurons 31:03 – Masculine vs. Feminine Energy 45:05 – Lithium Orotate 49:52 – Protein & Longevity 54:02 – Semen Retention 59:46 – Prolactin & Long-Term Desire 1:09:12 – Sex & Mirror Neurons 1:12:45 – The Five Finger Ask See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

I am honored and delighted to have Vanessa Spina join me on the podcast today!  Vanessa is the best-selling author of Keto Essentials and a sports nutrition specialist whose expertise on the ketogenic diet has left a lasting impact on countless lives! With a background in biomedical science and a multifaceted career as an international stockbroker, she has pioneered a journey in the health and wellness industry that is nothing short of remarkable!  In this episode, we dive deep into the fascinating realm of nutrition, from unraveling the mysteries of protein-recommended daily allowances and the leucine threshold to exploring the pivotal role of strength training in metabolic health. We dispel common misconceptions about the ketogenic diet, debunk the deceptive nature of the scale, and unveil the significance of DEXA scans in understanding changes in body composition. Vanessa also sheds light on the crucial importance of mitochondrial health and shares invaluable insights on various methods, including red light therapy, cold thermogenesis, micronutrients, and structured supplementation, to support our cellular powerhouses.  Join Vanessa and me on a knowledge-rich journey to uncover the keys to optimal health and well-being! IN THIS EPISODE YOU WILL LEARN: Common misconceptions about ketogenic diets Why a traditional ketogenic diet is not for everyone Why macronutrients are essential Misinformation regarding the recommended daily allowance for protein How to build muscle The relationship between metabolic health and muscle health The importance of DEXA scans for understanding body composition Why resistance training is a priority How to support the mitochondria The benefits of red light therapy and cold therapy Connect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community (The Midlife Pause/Cynthia Thurlow)  Cynthia's Menopause Gut Book is on presale now! Cynthia's Intermittent Fasting Transformation Book The Midlife Pause supplement line Connect with Vanessa Spina On her ⁠website⁠ (ketogenicgirl.com) ⁠The Optimal Protein Podcast⁠ Vanessa's Book ⁠Keto Essentials: 150 Ketogenic Recipes to Revitalize, Heal, and Shed Weight ⁠ Resource: Use Code CYNTHIA for $20 OFF any of the Tone ⁠LUX devices⁠.

Body image researcher and Rutgers University psychology professor Dr. Charlotte Markey is back for a second time on the podcast. She has spent nearly three decades researching body image, and has written books for tweens, teens, boys, girls, and adults.We get into so much…including:* Body image as relational: how environment and relationships shape how we feel in our bodies* The father dynamic, achievement culture, and how a critical home environment affects girls* Biohacking and wellness culture as diet culture in disguise* What happens when food gets moralized into good and bad* Parents disparaging their own bodies and how it lands on daughters* Body dissatisfaction across racial, cultural and socioeconomic backgrounds* Puberty: why normalizing it matters and why the conversation needs to extend beyond adolescence* How diet culture exploits women's hormonal life stages* Whether there is a critical window for body image intervention* Social media's impact on body shame and how to learn media literacy for critical thinking and protection* Body diversity and why the bodies we're sold are not achievable for most people* The protein obsession in wellness culture and why it's concerning in adolescents* What to do when your daughter is already struggling* How parents can audit their own relationship with food and body in service of their kidsCharlotte Markey, Ph.D., is a world-leading expert in body image research, having studied body image and eating behavior for nearly three decades. She is passionate about understanding what makes us feel good about our bodies and helping people to develop a healthy body image and relationship with food. Charlotte is an experienced book author, research scientist, clinician, speaker, and psychology professor at Rutgers University, Camden.Her books: https://www.thebodyimagebook.com/Instagram: https://www.instagram.com/char_markeySubstack: https://drcharlottemarkey.substack.com/Find Full Plate on Instagram: https://www.instagram.com/fullplate.podcast/Find Abbie on Instagram: https://www.instagram.com/abbieattwoodwellness/Subscribe to the newsletter: https://abbieattwoodwellness.substack.com/Listen to the first episode with Dr. Charlotte MarkeyFull Plate by Abbie Attwood is a reader-supported publication. To receive special posts, bonus episodes, and support this work, consider becoming paid subscriber. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit abbieattwoodwellness.substack.com/subscribe

If you are constantly bloated, fatigued, and feeling heavy, your gut bacteria have taken over. The standard advice is to just stop eating and do a multi-day water fast. But if your gut is already inflamed, a strict zero-calorie fast will actually spike your cortisol, trigger adrenaline crashes, and blow open the tight junctions in your intestinal wall.In this video, I break down the Italian fasting hack engineered by longevity researcher Valter Longo: The Fasting Mimicking Diet (FMD).I explain exactly how to structure this 5-day protocol to trick your body into autophagy (cellular cleanup) while still eating 800 to 1100 calories of specific fats and complex carbs. You will learn how constant "grazing" paralyzes your Migrating Motor Complex, why hidden proteins in vegetables are secretly kicking you out of fasting mode, and the exact step-by-step protocol to re-feed your microbiome on Day 6 without causing a massive inflammatory storm.Thank you to our sponsors!-GOT MOLD? | Go to http://gotmold.com/shopand use DAVE10 to save 10% and see what's in your air-The One Device | Use code DAVE for $10 off at theonedevice.com/dave-iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVETimestamps:00:00 – Intro00:40 – Gut Ecosystem01:00 – Constant Snacking02:57 – Gut-Brain Connection03:40 – Why Standard Fasting Can Backfire07:22 – The Fasting Sweet Spot09:21 – Introducing the FMD10:43 – Pre-Reset: Prep Days13:24 – The 5-Day FMD Protocol16:47 – Meal Timing & Circadian Rhythm17:46 – Sleep, Stress & Recovery18:22 – How Often to Do FMD19:23 – WrapupConnect with Dave Asprey!Website: https://daveasprey.comTikTok: https://www.tiktok.com/@daveaspreyofficialInstagram: https://www.instagram.com/dave.asprey/Facebook: https://www.facebook.com/Daveaspreyofficial/X: https://x.com/daveaspreyYouTube: https://www.youtube.com/c/daveaspreybprThe Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/Danger Coffee: https://dangercoffee.com/DAVE15Dave Asprey's BEYOND Conference: https://beyondconference.com/Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15Upgrade Labs: https://upgradelabs.com40 Years of Zen: https://40yearsofzen.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Cam Cordin called in to talk all about the extreme biohacking routine that changed his life including cold plunges, carnivore diet, peptides and more. Tune in to hear all the details including how he wound up with major nerve damage and pain how and why it became permanent, the supplements and different things he tried to cure his nerve pain and what they each did and did not do for his pain, how he started cold plunging and the instant benefits he got from it, his three failed marriages and how and when he decided to reflect on his past negative patterns and what he realized about himself, the peptide he started using after a concussion and what it wound up doing for him, how and why he started the carnivore diet, what he eats the most and how he feels on it, how and why being hydrated is important and how much water people should drink, the concoction he uses to get good sleep, how he now helps men and what he helps them with plus a whole lot more. Find out more on Savage Chill Style GET A COPY OF THE STRICTLY ANONYMOUS BOOK! Strictly Anonymous Confessions: Secret Sex Lives of Total Strangers. A bunch of short, super sexy, TRUE stories. GET YOUR COPY HERE: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://amzn.to/4i7hBCd⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  or Pre-order audiobook version ⁠⁠⁠⁠⁠here⁠⁠⁠⁠   To see HOT pics of my female guests + hear anonymous confessions + get all the episodes early and AD FREE, join my Patreon! It's only $7 a month and you can cancel at any time. You can sign up here: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.patreon.com/StrictlyAnonymousPodcast⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ and when you join, I'll throw in a complimentary link to my private Discord! To join SDC and get a FREE Trial! click here: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.sdc.com/?ref=37712⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ or go to SDC.com and use my code 37712 Want to be on the show? Email me at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠strictlyanonymouspodcast@gmail.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ or go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠http://www.strictlyanonymouspodcast.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ and click on "Be on the Show." Want to confess while remaining anonymous? Call the CONFESSIONS hotline at 347-420-3579. All voices are changed.   Sponsors:   ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://LOADBOOST.COM⁠⁠⁠⁠⁠⁠ - To get 10% off LOAD BOOST by VB Health, use code: STRICTLY  ⁠⁠⁠⁠https://Motorbunny.com/Strictly⁠⁠⁠⁠ - For $50 off your whole order  ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://bluechew.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ — Buy 2 months of Bluechew GOLD and get the third month FREE! Use code: STRICTLYANON⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠   ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.quince.com/strictlyanon⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ — For premium quality Quince clothing plus FREE shipping and 365 day returns!  ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://beducate.me/pd2614-anonymous —⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Click here to take the quiz and  get your personalized roadmap to sexual happiness Follow me! Instagram  ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/strictanonymous/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ X  ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://twitter.com/strictanonymous?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Website  ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠http://www.strictlyanonymouspodcast.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Everything else: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://linktr.ee/Strictlyanonymouspodcast⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices

*Testosterone Directly Suppresses Brain Tumor Growth in Males by 38% Cleveland Clinic research funded by NIH shows testosterone binds androgen receptors in glioblastoma stem cells — the root of tumor recurrence — and cuts growth by 38% when levels are restored. Dave breaks down why the mainstream framing of testosterone and cancer risk has it backwards, what androgen deprivation therapy may be doing to every other cancer pathway simultaneously, and why your hormone panel is now a cancer conversation, not just a performance one. Sources: -https://www.nih.gov/news-events/news-releases/nih-funded-study-suggests-testosterone-suppresses-brain-tumor-growth-males -https://bioengineer.org/nih-funded-research-indicates-testosterone-may-inhibit-brain-tumor-growth-in-males/ *CDC Halts Rabies Testing Nationwide A CDC staffing crisis has pushed rabies, mpox, and Epstein-Barr testing to overwhelmed state labs, creating one-to-two week diagnostic delays in a disease where post-exposure prophylaxis must begin within ten days of a bite — and where fatality is virtually 100% once symptoms appear. Dave explains exactly what to do if you or a pet is exposed, why outdoor biohackers are the most exposed population, and what pre-travel prevention looks like for anyone heading to endemic regions. Sources: -https://www.nbcnews.com/health/health-news/cdc-pauses-testing-rabies-monkeypox-epstein-barr-viruses-rcna266377 -https://www.cidrap.umn.edu/rabies/state-public-health-labs-step-cdc-pauses-testing-various-pathogens-including-rabies-mpox *Mifepristone Mail Ban The Supreme Court issued a one-week stay blocking a 5th Circuit ruling that would have ended telehealth and mail access to mifepristone, used in over 63% of U.S. abortions. Dave sets aside the moral debate to focus on what this legal precedent means for FDA-approved compounded peptides, bioidentical hormones, and telehealth access to any treatment without full pharmaceutical backing — and why this case is one every biohacker should be tracking closely. Sources: -https://www.usnews.com/news/health-news/articles/2026-05-05/supreme-court-issues-stay-keeping-abortion-pill-mifepristone-available-by-mail-for-now -https://www.npr.org/2026/05/04/nx-s1-5810510/supreme-court-mifepristone-appeals-telehealth *Cow Flu and Dog Coronavirus University of Florida scientists are watching Influenza D — endemic in U.S. cattle herds — and canine coronavirus HuPn-2018, which already jumped to humans in China, as the two zoonotic threats most likely to achieve widespread human transmission. Dave covers why the conditions producing these jumps aren't going away, what the Influenza D finding means for the raw milk conversation right now, and the mucosal immunity stack that puts you in the strongest position regardless of which virus makes the leap next. Sources: -https://ufhealth.org/news/2026/scientists-say-these-two-viruses-may-become-the-next-public-health-threats -https://www.gavi.org/vaccineswork/six-major-health-threats-could-shape-2026-heres-what-experts-are-watching *Hantavirus Kills 3 on Cruise Ship Eight confirmed or suspected cases of Andes hantavirus aboard the MV Hondius off the Canary Islands have killed three and left two critical, with passengers from 23 countries already dispersed through global airports. Dave cuts through the pandemic panic to explain why American and South American hantavirus strains are categorically more lethal than European ones, why Andes is the only strain on earth that spreads human to human via respiratory droplets, and what early symptom recognition could mean for your survival window if exposure reaches your community. Sources: -https://www.cnn.com/2026/05/07/world/hantavirus-ship-tenerife-outbreak-intl -https://www.nbcnews.com/health/health-news/hantavirus-andes-virus-what-is-cruise-ship-outbreak-deadly-strain-rcna343901 This episode is designed for biohackers, longevity seekers, and high-performance listeners who want mechanism-level clarity on hormonal optimization, infectious disease risk, immune resilience, and the legal infrastructure shaping medical autonomy. Host Dave Asprey connects emerging NIH research, Supreme Court developments, and live outbreak data into actionable frameworks for protecting your biology when institutions can't do it for you. New episodes every Tuesday, Thursday, Friday, and Sunday. Keywords: testosterone brain cancer, testosterone glioblastoma, low testosterone tumor risk, androgen deprivation therapy cancer, CDC rabies testing paused, rabies post-exposure prophylaxis, rabies exposure protocol, mifepristone telehealth ban, SCOTUS mifepristone stay, telehealth medical autonomy, compounded hormones legal risk, influenza D cattle virus, canine coronavirus HuPn-2018, zoonotic virus 2026, raw milk bird flu risk, mucosal immunity biohacking, hantavirus cruise ship, Andes hantavirus outbreak, MV Hondius hantavirus, hantavirus human to human transmission, hantavirus vs coronavirus, biohacking news 2026, Dave Asprey weekly roundup, longevity research 2026 Thank you to our sponsors! - Dave Asprey's 2026 Clean Nicotine Roadmap | Enroll for free at: daveasprey.com/2026-clean-nicotine-roadmap - Essentia | Go to https://myessentia.com/dave and use code DAVE for $100 off The Dave Asprey Upgrade. - iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE Resources: • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Intro 00:35 – 1. Testosterone & Brain Cancer 02:30 – 2. CDC Pauses Rabies Testing 04:09 – 3. Mifepristone & Telehealth Access 05:42 – 4. Influenza D & Canine Coronavirus 07:15 – 5. Hantavirus Cruise Ship Outbreak 09:36 – Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What if an invisible field could protect your brain from EMF damage, improve your HRV, accelerate recovery, and optimize your biology without pills, devices, or a single lifestyle change? Host Dave Asprey sits down with Philippe Samor von Holtzendorff-Fehling, founder of Leela Quantum Tech and Quantum Upgrade, to explore one of the most controversial and compelling frontiers in biohacking today: quantum energy fields delivered remotely, in real time, to your body, your pets, your home, and even your business. -Try Quantum Upgrade Free for 15 days, no credit card required: quantumupgrade.io/dave -Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Philippe Samor von Holtzendorff-Fehling is a coach, conscious entrepreneur, and energy healer who built a parallel path alongside a high-level international business career, working through his own blockages to fully connect with his true self. He served as Vice President at both T-Mobile International and T-Mobile US, and is now the founder and CEO of Leela Quantum Tech and Quantum Upgrade. He is also a kundalini yoga teacher, a passionate bio and bio-energy hacker, a father of two, a dog lover, and the number one ranked tennis player in the US in the Men 50+ category. His work sits at the intersection of functional medicine, quantum biology, and human performance, and the science behind his technology is harder to dismiss than most people expect. Dave and Philippe go deep on how chronic EMF exposure from 5G towers, Starlink satellites, electric vehicles, and everyday Wi-Fi actively disrupts your brain waves, blood cells, heart rate variability, and mitochondria function. They also break down how Quantum Upgrade works as a remote, customizable field that can harmonize these frequencies in real time, and why it may be one of the most underrated tools for sleep optimization, brain optimization, recovery, anti-aging, and longevity. This episode also covers the groundbreaking work Philippe is doing with autistic children, including a clinical study showing measurable reductions in autism spectrum scores, and a remarkable collaboration with Susie Miller of the Telepathy Tapes. This is essential listening for anyone serious about biohacking, human performance, anti-aging, longevity, brain optimization, sleep optimization, functional medicine, mitochondria health, and hacking every system in your body with smarter not harder solutions. You'll Learn: Why EMF from 5G, Starlink, and electric vehicles is more biologically dangerous than most people realize How a 256-channel EEG captured real-time brain changes triggered by Quantum Upgrade What "quantum coherence" actually means for your biology and why it matters for human performance and longevity How remote quantum fields affect HRV, blood clarity, ATP production, and mitochondria function Why autistic children showed measurable spectrum score reductions in a clinical trial using this technology How to customize your own quantum field for sleep optimization, recovery, energy, and brain optimization What Dave uses Quantum Upgrade for at his 40 Years of Zen facility in Austin Thank you to our sponsors! - Superstratum Labs | Get Dave's exact home mold detox kit and save 10% at superstratumlabs.com/products/dave - Suppgrade Labs | Grab your DAKE and Minerals 101 duo at shopsuppgradelabs.com and use code DAVEPOD for 15% off today - Timeline | Go to timeline.com/dave and you'll get an additional 20% off your first month - Amp | If you're ready to make fitness fit into your life, go to amp.ai to check it out Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Philippe Samor von Holtzendorff-Fehling, Quantum Upgrade, Leela Quantum Tech, quantum energy, EMF protection, electromagnetic fields, 5G health effects, Starlink radiation, biohacking, human performance, longevity, anti-aging, brain optimization, sleep optimization, mitochondria, functional medicine, HRV, heart rate variability, dark field microscopy, EEG, ATP production, quantum coherence, biofield, energy healing, autism spectrum, telepathy tapes, Susie Miller, kundalini yoga, electric vehicle EMF, Wi-Fi health effects, smarter not harder, Dave Asprey, 40 Years of Zen, wound healing, placebo controlled trials, quantum biology, coherent field, EMF harmonization, remote quantum field, energy frequency, conscious entrepreneurship Resources: • Try Quantum Upgrade Free for 15 days, no credit card required: quantumupgrade.io/dave • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 01:15 – What Science Can't Explain 04:05 – What Is Quantum Upgrade? 06:04 – The Research 07:47 – Origin Story 12:20 – EEG Testing & Brain Effects 12:53 – EMFs, Electric Cars & 5G 17:57 – Measuring Results 21:25 – Autism Study & Telepathy Tapes 26:16 – Frequencies & Settings 29:09 – Starlink & Global EMF 30:54 – Skeptics & Proof 33:08 – Kids & Pets 37:10 – Wrap-Up & Free Trial See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

For many entrepreneurs, mental health takes a back seat to ambition, productivity, and the pressure to keep going no matter what. Dr. Aditi Nerurkar once lived by that belief, until chronic burnout during her 80-hour-a-week residency broke her body down so severely she feared a heart condition. That crisis sparked her healing journey and became the foundation for her 5 Resets for when life and business get hard. In this first episode of the Mental Wealth Series, Dr. Aditi shares science-backed tools to help entrepreneurs reduce stress, prevent burnout, and protect their mental health.  In this episode, Hala and Dr. Aditi will discuss:  (00:00) Introduction (01:52) The Global Stress and Burnout Crisis (03:37) Good Stress vs. Bad Stress  (05:36) Your Brain's Fight-or-Flight Response (10:19) True Resilience vs. Toxic Resilience (13:05) Dr. Aditi's Personal Burnout Breaking Point (37:00) The Five Resets Framework  (44:45) The “Buried Treasure” Wellness Exercise (52:11) Digital Boundaries for Mental Health (1:00:40) Monotasking for Focus and Productivity Dr. Aditi Nerurkar is a physician, public health expert, and Harvard Medical School faculty member specializing in stress, burnout, resilience, and mental health. She is also a nationally sought-after speaker, television correspondent, and the bestselling author of The 5 Resets, a science-backed guide to managing stress and improving mental well-being.  Sponsored By: Huel - Get over $50 in savings with the Discovery Bundle from Huel. Use my exclusive code YAP15 for 15% off at huel.com/yap15. Indeed - Get a $75 sponsored job credit to boost your job's visibility at Indeed.com/profiting Shopify - Start your $1/month trial at Shopify.com/profiting. Quo - Run your business communications the smart way. Try Quo for free, plus get 20% off your first 6 months when you go to quo.com/profiting Fabric - Protect your family with term life insurance from Fabric by Gerber Life. Apply today in just minutes at meetfabric.com/profiting  ZocDoc - Stop putting off those doctors' appointments. Find and instantly book a doctor you love today at Zocdoc.com/PROFITING  Blinkist - Turn the world's best nonfiction books into quick 15-minute reads or listens. Grab your free trial plus an exclusive 30% discount at blinkist.com/profiting   Remitly - Transfer money internationally with Remitly, with no hidden fees. Use code BUSINESS to get a $100 bonus after you send $300 or more. New customers only.  Prolon - Reset and rejuvenate your body with Prolon's five-day plant-based fasting mimicking program. Go to ProlonLife.com/PROFITING for 15% off sitewide plus a $40 bonus gift when you subscribe to their 5-Day Program. Resources Mentioned: Dr. Aditi's Book, The 5 Resets: bit.ly/AN-T5R  Dr. Aditi's Website: draditi.com Dr. Aditi's Instagram: instagram.com/draditinerurkar Mental Wealth Playbook: yapmedia.com/mentalwealth  Active Deals - youngandprofiting.com/deals  Key YAP Links Reviews - ratethispodcast.com/yap YouTube - youtube.com/c/YoungandProfiting Newsletter - youngandprofiting.co/newsletter  LinkedIn - linkedin.com/in/htaha/ Instagram - instagram.com/yapwithhala/ Social + Podcast Services: yapmedia.com Transcripts - youngandprofiting.com/episodes-new  Entrepreneurship, Entrepreneurship Podcast, Business, Business Podcast, Self Improvement, Self-Improvement, Personal Development, Starting a Business, Strategy, Investing, Sales, Selling, Psychology, Productivity, Entrepreneurs, AI, Artificial Intelligence, Technology, Marketing, Negotiation, Money, Finance, Side Hustle, Startup, Mental Health, Career, Leadership, Mindset, Health, Growth Mindset, Biohacking, Motivation, Manifestation, Brain Health, Life Balance, Self-Healing, Positivity, Happiness, Sleep, Diet

Your biological age can drop by over three years in just eight weeks, and the tools to do it are already in your kitchen. This episode breaks down the cutting-edge science of methylation, polyphenols, Yamanaka mimetics, and epigenetic reprogramming that is rewriting what we know about anti-aging, longevity, and human performance. -Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Dr. Kara Fitzgerald, ND, IFMCP, a leading voice in functional medicine and epigenetic aging research. Her award-winning clinical studies published in Aging (2021, 2023, and 2025) proved that targeted diet and lifestyle interventions can measurably reverse biological age on validated epigenetic clocks. She is the author of Younger You, an IFM faculty member and Certified Practitioner, and one of the most rigorously credentialed researchers working at the intersection of functional medicine, nutrition, and longevity science today. Together, they go deep on Yamanaka factors, the Nobel Prize-winning discovery that can wind back a 90-year-old cell to its 20s, and the emerging class of compounds called Yamanaka mimetics, polyphenol-based supplements that may replicate some of those same cellular rejuvenation effects without the risks. They cover why polyphenols do the heavy lifting in biological age reversal, how AI is accelerating longevity research, and why the dark matter of nutrition may matter more than macros, carnivore protocols, or ketosis for long-term health. They also get into oxalates, mitochondria, fibroids, ovarian rejuvenation, and why the original Horvath clock may be more relevant than scientists thought. This is essential listening for anyone serious about biohacking, longevity, supplements, functional medicine, anti-aging, brain optimization, human performance, and using smarter not harder strategies to take control of your biology. You'll Learn: How diet, supplements, and meditation reversed biological age by over three years in eight weeks in a randomized controlled trial What Yamanaka factors are and why scientists are calling partial cellular reprogramming the future of anti-aging Which polyphenols do the heaviest lifting for epigenetic rejuvenation, including EGCG, urolithin A, rosemary, marjoram, and yarrow Why the Horvath epigenetic clock may actually be touching on programmatic aging rather than just exposomic wear and tear How AI is unlocking patterns in longevity data that no human researcher could find alone The problem with high-oxalate superfoods and how to get polyphenol benefits without the inflammatory downside Why ovarian rejuvenation may be the highest-leverage Yamanaka application for women's longevity and brain health How compounds like AKG, sodium butyrate, and forskolin may act as Yamanaka mimetics already available today What the PRC2 polycomb clock reveals about programmatic aging and why it matters more than second-generation clocks Why perimenopause does not have to be painful, and how functional medicine addresses it at the root Thank you to our sponsors! - Screenfit | Get your at-home eye training program for 40% off using code DAVE at https://www.screenfit.com/dave. - Viome | Check it out at viome.com and use code 10DAVE for 10% off. It's time to stop guessing and start knowing your body. - STEMREGEN | Go to stemregen.co/dave30 Use code DAVE30 for 30% OFF your next order. - Caldera + Lab | Go to https://calderalab.com/DAVE and use code DAVE at checkout for 20% off your first order. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Kara Fitzgerald, biological age reversal, epigenetics, DNA methylation, Yamanaka factors, polyphenols, EGCG, urolithin A, anti-aging, longevity, biohacking, functional medicine, supplements, mitochondria, epigenetic clock, cellular reprogramming, AKG, sodium butyrate, methylation, Steve Horvath, Vittoria Sebastiano, coleus, perimenopause, ovarian rejuvenation, pluripotent stem cells, PRC2, dark matter of nutrition, TRIM study, dihydroxyflavone, BDNF, Prenuvo, chemical cellular rejuvenation Resources: • Learn more about all of Dr. Fitzgerald's work at: https://www.drkarafitzgerald.com/ • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 0:00 – Trailer 1:28 – Explaining Study 3:45 – What Is The Diet 6:49 – Age Reversal 8:17 – Polyphenols vs. Supplements 9:27 – Food vs. Supplement Dosing 12:41 – Oxalate & Polyphenol Trade-offs 18:41 – Yamanaka Factors Explained 28:59 – Chemical Cocktails 32:15 – PRC2 Clocks & Programmatic Aging 40:28 – Seasonal Eating 43:40 – Carnivore Diet: Short vs. Long Term 45:31 – Inuit Diet 46:39 – Flavones & Brain-Crossing Compounds 48:50 – Why Only Men in the Study? 51:05 – Women, Perimenopause & the Protocol 53:20 – Fibroids & Gaps in Women's Research See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

I spent fifteen years living with brain fog until I realized the problem wasn't in my brain, but in a nervous system stuck in a survival mode that pulls energy away from focus and memory. In this video, I explain why "trying harder" or popping supplements rarely works, and instead, I show you the 9,000-year-old ritual of heat and cold that pulls your body out of stress mode so clarity can actually return. I break down the specific science of how I use infrared wavelengths and contrast therapy to retrain the brain to stay calm under pressure, moving beyond temporary fixes to target the root cause of mental fatigue. Follow this protocol to finally complete your body's stress cycles, reset your biological default settings, and reclaim the lasting mental performance you've been missing.00:00 – Introduction01:02 – What Brain Fog Really Is03:00 – Why Trying Harder Doesn't Work04:51 – Supplements: Useful But Not Enough06:14 – Why Sauna Works07:32 – Infrared vs Traditional Sauna08:02 – Sunlighten Sauna Overview09:28 – Sauna Routine & Protocol10:34 – Why Home Access Matters11:41 – Post-Session Recovery12:11 – Contrast Therapy13:11 – How to Do Contrast Therapy13:54 – Closing & TakeawaysThank you to our sponsors!-TRU KAVA | Head to trukava.com and use code DAVE10 for 10% off.-Neuronic | Go to www.neuronic.online Code DAVE for $100 off-iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVEConnect with Dave Asprey!Website: https://daveasprey.comTikTok: https://www.tiktok.com/@daveaspreyofficialInstagram: https://www.instagram.com/dave.asprey/Facebook: https://www.facebook.com/Daveaspreyofficial/X: https://x.com/daveaspreyYouTube: https://www.youtube.com/c/daveaspreybprThe Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/Danger Coffee: https://dangercoffee.com/DAVE15Dave Asprey's BEYOND Conference: https://beyondconference.com/Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15Upgrade Labs: https://upgradelabs.com40 Years of Zen: https://40yearsofzen.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

This week's stories: *Mud Playgrounds Double Kids' Bacterial Diversity and Spike Immune Genes 30% Finland swapped rubber playground surfaces for natural soil and mud across eight kindergartens — and after just one month, kids in dirt had twice the bacterial species diversity on their skin and a 30% increase in expression of ten immune-related genes. Dave breaks down why your immune system requires microbial exposure to calibrate properly, what the hygiene hypothesis actually means for adults, and the dead-simple weekly habit that primes your innate immunity the same way. Sources: https://creators.yahoo.com/lifestyle/story/finland-replaced-artificial-playground-surfaces-with-natural-elements-like-mud-and-soil--and-the-results-surprised-even-researchers-184318556.html https://www.sciencedaily.com/releases/2026/04/mud-playground-immunity.htm *Mixing Exercise Types Cuts All-Cause Mortality Up to 40% in 170,000-Person Study A 30-year BMJ Medicine cohort study found that people who rotate at least three different types of exercise weekly see 19 to 40% lower all-cause mortality — and that benefit held independent of total training volume. Dave explains why variety is a distinct biological signal, not a motivation trick, and why grinding more of the same thing is leaving longevity gains on the table. Sources: https://bmjmedicine.bmj.com/content/early/2026/04/26/bmjmed-2025-001513 https://www.sciencedaily.com/releases/2026/04/260426012305.htm https://www.theguardian.com/society/2026/apr/26/exercise-diversity-mortality *Facial Aging Rate from Photos Predicts Cancer Survival Better Than Blood Biomarkers AI analysis of serial facial photos in 1,000+ cancer patients found that computed facial aging rate independently predicted five-year survival with a hazard ratio of 2.1 — outperforming CRP and other standard blood markers. Dave covers what the AI is actually reading in those photos, why your face is a more accurate biological ledger than most labs your doctor orders, and the free monthly habit that turns this into an early warning system. Sources: https://medicalxpress.com/news/2026-04-photos-reveal-faster-biological-aging.html https://www.nature.com/articles/s43587-026-00123-4 *Vibration Vest OsteoBoost Mimics Weight-Bearing Exercise to Rebuild Bone Density OsteoBoost raised $8M for a wearable vest delivering 30–50Hz vibrations to the spine and hips, triggering the same Wnt/β-catenin osteoblast pathway activated by mechanical loading — with early trials showing 2–5% bone mineral density gains in six months. Dave makes the case forwhy bone loss is one of the most underrated aging crises in the biohacking community, and who should be watching this category closely. Sources: https://longevity.technology/news/osteoboost-raises-8m-to-scale-bone-wearable/ https://www.crunchbase.com/organization/osteoboost *10+ States Advance Raw Milk Bills as H5N1 Hits 100+ Dairy Herds Legislation expanding raw milk access is moving in Arizona, Iowa, New Hampshire, and elsewhere — while the CDC flags H5N1 in over a hundred dairy herds with documented aerosol transmission concerns. Dave gives an honest read on where the freedom argument, the microbiome argument, and the current risk calculus actually stand in April 2026, and what more rigorous sourcing looks like right now. Sources: https://www.yahoo.com/news/articles/us-med--raw-milk-legislation-120124275.html https://www.cdc.gov/flu/avianflu/dairy.htm This episode is designed for biohackers, longevity seekers, and high-performance listeners who want mechanism-level clarity on immune priming, exercise science, biological age tracking, bone health, and real food risk assessment. Host Dave Asprey connects emerging clinical research, large-scale cohort data, and real-world protocols into actionable frameworks for extending healthspan and sharpening performance. New episodes every Tuesday, Thursday, Friday, and Sunday. Keywords: mud playground immune system microbiome, soil bacteria skin diversity, hygiene hypothesis biohacking, exercise variety longevity, BMJ exercise mortality study, mixed training lifespan, facial aging rate cancer survival, biological age face AI, facial photo biomarker longevity, OsteoBoost vibration vest bone density, whole body vibration osteoporosis, bone mineral density wearable, raw milk H5N1 bird flu, raw milk legislation 2026, raw dairy safety biohacking, biohacking news, longevity research 2026, Dave Asprey weekly roundup Thank you to our sponsors! - KILLSwitch | If you're ready for the best sleep of your life, order now at https://www.switchsupplements.com/and use code DAVE for 20% off - Puori | Go to Puori.com/DAVE or use code DAVE at checkout to get 32% off your Puori Fish Oil subscription. You save more than $18. - iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE Resources: • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Intro 00:20 – Dirt & Immune Training 02:22 – Exercise Variety & Longevity 04:16 – Facial Aging as a Health Biomarker 05:47 – Bone Loss & Vibration Tech 07:31 – Raw Milk & H5N1 Risk 09:20 – The Wrapup See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.