Podcasts about Management

Episode: 1491 In which business schools study a leaderless orchestra.  Today, we have no leader.

Creating Organizational Cultures That Actually Work In this episode, Michael and cultural anthropologist Jitske Kramer dive deep into the heart of organizational culture. Michael shares a story from a startup he supported, where a crystal clear sense of purpose created unity, loyalty, and a genuine feeling of belonging. Employees stayed because they felt connected to something bigger than a job description. Jitske expands on this by highlighting how leaders shape culture through the behaviors, values, and norms they model. She stresses that culture is never an accident. It is a series of daily choices and conversations. When leaders fail to engage with their teams or invite them into meaningful decision making, organizations lose clarity and people lose their sense of belonging. Both Michael and Jitske agree that leaders miss countless opportunities to build trust simply because they are not intentionally engaging with their people. Transformative Leadership and the Power of Human Connection Michael brings up a powerful metaphor involving an orchestra conductor to show how communication and knowledge flow can transform the relationship between leaders and their teams. When the conductor shifts from directing to connecting, the entire ensemble transforms. The energy changes. People take ownership. Collaboration becomes natural rather than forced. Jitske builds on this idea by contrasting transactional interactions with transformative ones. Transactional moments keep the lights on, but transformative moments build the future. She emphasizes the need for what she calls campfire conversations. These are the unhurried, human centered discussions where ideas form, trust deepens, and innovation actually has space to emerge. They conclude that the most successful organizations are the ones that prioritize human to human connection over rigid systems and corporate scripts. Finding Clarity in the Messy Middle of Change Jitske introduces her latest book, Tricky Times, which explores liminality. Liminality refers to the messy middle stage of change when the old story no longer works and the new story is not yet formed. She describes this phase as uncomfortable but deeply necessary. She explains that societies worldwide are wrestling with a kind of midlife crisis. People are questioning the expectation of nonstop economic growth and the conflict it creates with environmental and social realities. In these liminal spaces, power dynamics shift. Cultural identities get rewritten. Leaders are challenged to redefine what truly matters. Michael shares how timely these insights feel, especially given the current political climate in the United States and abroad. He highlights how difficult but essential conversations shape whether we move forward with intention or stay stuck in old patterns. Leading with Courage in Tricky Times Jitske describes the leadership challenges she writes about in Tricky Times. She warns against leaders who act like tricksters, constantly pushing boundaries without offering guidance or stability. True leadership requires bold honesty, grounded decision making, and the willingness to enter uncomfortable conversations. She emphasizes that balanced leadership is essential. Leaders must be willing to question assumptions, tell the truth about what is working and what is not, and invite their organizations into deeper reflection. Tricky Times has become a bestseller in the Netherlands, and Jitske is sharing its message with influential political leaders who are navigating uncertainty on a national scale. The book is available as an e-book on Amazon and offers a grounded, human centered framework for leading through cultural transformation. Jitske Kramer is a renowned Dutch corporate anthropologist who translates real-world lessons from communities around the globe into practical tools for modern workplaces.    She travels the world to learn from traditional healers, innovators, random passers-by, and everyday communities, studying how humans bond, lead, and resolve conflict — and brings those insights into the boardroom.   Her latest book, Tricky Times (a #1 Dutch bestseller), explores what it takes to lead in “the messy middle” — those uncertain in-between phases where old systems break down before new ones emerge.    With 25+ years of experience, she has shaped transformation for Nike, Unilever, Calvin Klein, and Philips, authored 9 bestselling books (150,000+ copies sold), and spoken alongside Simon Sinek, Amy Edmondson, Yuval Noah Harari on stages like TEDx and Workhuman Live.   Jitske's sharp, funny, and “aha”-filled style makes anthropology highly accessible for leaders facing change, culture challenges, and transformation.   Topics:  The messy middle: Leading effectively through uncertainty and liminal times The real drivers of company culture: Rituals, symbols, and hidden power structures How to “think like an anthropologist” to sense change and spot unseen dynamics The difference between formal power and cultural power — and why rank-awareness is critical for leaders What tribes can teach today's organizations about handling dilemmas and conflict   More about Jitske:  Founder of HumanDimensions, a pioneering training company that helps organizations strengthen teamwork and company culture.  Featured in the Patterns of Life documentary series, in which she traveled to India as an anthropologist.  Former Fellow at the Oxford Leadership Academy; holds a master's degree in cultural anthropology from Utrecht University.  Other books by Jitske: Building Tribes, Wow! What a Difference, Work Has Left the Building, Jam Cultures, andThe Corporate Tribe (which won the prestigious 2016 Management book of the Year Award). Take a look at Jitske's keynotes, other public speeches, TV appearances, and writings.    To get a sense of Jitske, here's an appearance she made on The Culture Lab podcast, talking about the making of a corporate tribe and how to effectively deal with diversity in a team. 

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Send us a textAbout Dr. Sheila Morrison:She studied at Pacific University College of Optometry, where she earned her Doctor of Optometry and completed a Masters Degree in Vision Science, with a research focus on scleral contact lenses and specialty contact lens design. Dr. Morrison went on to be awarded placement to a highly competitive residency in cornea & contact lenses, which she also completed at Pacific University and the Portland Veteran Affairs Hospital.Her academic and clinical accomplishments are well renowned in the eye care world and she appreciates being regularly invited to lecture internationally about specialty contact lenses and myopia control. She has expertise in contact lens fitting for patients of all ages and eye conditions including: medically necessary lenses for infants, scleral lenses for the irregular cornea (ie Keratoconus) or severe dry eye, and orthokeratology (OrthoK) for myopia control.---If you're considering or have ever considered getting a virtual team member for your practice check out hiredteem.com, mention The Myopia Podcast when signing up for a $250 dollar discount off of your first month's teem member.https://hireteem.com/myopia-podcast/

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Send us a textAbout Philip Cheng:A Fellow of the International Academy of Orthokeratology and Myopia Control (FIAOMC) and with 19 years of clinical experience in the profession, Melbourne optometrist Philip Cheng is an internationally-recognised industry leader in myopia management. He is the director of Eyecare Concepts Melbourne, an independent practice with a focus on paediatric eye care, myopia control, orthoK and specialty contact lenses.Philip is dedicated to providing world-class, comprehensive myopia care to children and teenagers, and passionate about peer education as well as promoting public awareness of the issues around childhood myopia and the options now available to treat this progressive condition.He has been an industry spokesperson for Myopia Awareness Week, a consultant for the Brien Holden Vision Institute Academy, professional involvement in the Essilor Myopia Management Education Project, contributing writer for OA Pharma magazine, a presenter on myopia management for Optometry Australia and the University of Melbourne, and a Board Member of the Orthokeratology Society of Oceania. Recently he presented at the Global Myopia Symposium, Asia-Pacific Myopia Symposium and the World Council of Optometry Global Myopia Management Virtual Event.

Lawfare Managing Editor Tyler McBrien sits down with Cristin Dorgelo, a former senior adviser for management at the Office of Management and Budget, and Rob Storch, who served as the inspector general of the Defense Department until the Trump administration fired him and many of his colleagues in January of this year. They discuss those firings, other Trump administration attacks on the offices of the inspector general, and various attempts by the administration to undermine oversight and evade accountability, all covered in a new report from the Center on Budget and Policy Priorities called “Trump Administration's Undercutting of Oversight Hurts Taxpayers and Beneficiaries.”To receive ad-free podcasts, become a Lawfare Material Supporter at www.patreon.com/lawfare. You can also support Lawfare by making a one-time donation at https://givebutter.com/lawfare-institute.Support this show http://supporter.acast.com/lawfare. Hosted on Acast. See acast.com/privacy for more information.

After serving as Chief Legal Officer and then CFO at Salesforce, Amy Weaver sought a new challenge. She is now CEO of Direct Relief, which she tells host Jeff Berman is "the largest, most efficient, most effective, and most impactful global humanitarian group that you may never have heard of.” Weaver reveals scale lessons from Salesforce and how she's now applying them to amplify Direct Relief's vital work.Learn more about Direct Relief: directrelief.orgSubscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/newsletter/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

My conversation with Dr Emanuel begins at about 34 minutes Subscribe and Watch Interviews LIVE : On YOUTUBE.com/StandUpWithPete ON SubstackStandUpWithPete Stand Up is a daily podcast. I book,host,edit, post and promote new episodes with brilliant guests every day. This show is Ad free and fully supported by listeners like you! Please subscribe now for as little as 5$ and gain access to a community of over 750 awesome, curious, kind, funny, brilliant, generous soul In Eat Your Ice Cream, renowned health expert Dr. Ezekiel J. Emanuel argues that life is not a competition to live the longest, and that "wellness" shouldn't be difficult; it should be an invisible part of one's lifestyle that yields maximum health benefits with the least work Ezekiel J. Emanuel, MD, PhD, is the Vice Provost for Global Initiatives, the Co-Director of the Healthcare Transformation Institute, and the Diane v.S. Levy and Robert M. Levy University Professor at the University of Pennsylvania Perelman School of Medicine. Emanuel is an oncologist and world leader in health policy and bioethics. He is a Special Advisor to the Director General of the World Health Organization, Senior Fellow at the Center for American Progress, and member of the Council on Foreign Relations.  He was the founding chair of the Department of Bioethics at the National Institutes of Health and held that position until August of 2011. From 2009 to 2011, he served as a Special Advisor on Health Policy to the Director of the Office of Management and Budget and National Economic Council. In this role, he was instrumental in drafting the Affordable Care Act (ACA). Emanuel also served on the Biden-Harris Transition Covid Advisory Board. Dr. Emanuel is the most widely cited bioethicist in history.  He has over 350 publications and has authored or edited 15 books. His recent publications include the books Which Country Has the World's Best Health Care (2020), Prescription for the Future (2017), Reinventing American Health Care: How the Affordable Care Act Will Improve our Terribly Complex, Blatantly Unjust, Outrageously Expensive, Grossly Inefficient, Error Prone System (2014) and Brothers Emanuel: A Memoir of an American Family (2013). In 2008, he published Healthcare, Guaranteed: A Simple, Secure Solution for America, which included his own recommendations for health care reform. Dr. Emanuel regularly contributes to the New York Times, the Washington Post, the Wall Street Journal, The Atlantic, and often appears on BBC, NPR, CNN, MSNBC and other media outlets. He has received numerous awards including election to the National Academy of Medicine, the American Academy of Arts and Sciences, the Association of American Physicians, and the Royal College of Medicine (UK). He has been named a Dan David Prize Laureate in Bioethics, and is a recipient of the AMA-Burroughs Wellcome Leadership Award, the Public Service Award from the American Society of Clinical Oncology, Lifetime Achievement Award from the American Society of Bioethics and Humanities, the Robert Wood Johnson Foundation David E. Rogers Award, President's Medal for Social Justice Roosevelt University, and the John Mendelsohn Award from the MD Anderson Cancer Center. Dr. Emanuel has received honorary degrees from Icahn School of Medicine at Mount Sinai, Union Graduate College, the Medical College of Wisconsin, and Macalester College. In 2023, he became a Guggenheim Fellow. Dr. Emanuel is a graduate of Amherst College. He holds a M.Sc. from Oxford University in Biochemistry, and received his M.D. from Harvard Medical School and his Ph.D. in political philosophy from Harvard University. On YOUTUBE.com/StandUpWithPete ON SubstackStandUpWithPete   Listen rate and review on Apple Podcasts Listen rate and review on Spotify Pete On Instagram Pete on Blue Sky Pete on Threads Pete on Tik Tok Pete on Twitter Pete Personal FB page Stand Up with Pete FB page All things Jon Carroll  Gift a Subscription https://www.patreon.com/PeteDominick/gift Send Pete $ Directly on Venmo  

Hi beautiful besties!! Today has been a rough one for the two of us: Morgan has worked 7 days on with only one day off and Taylar spent the majority of her day running from doctors appt to doctors appts over some worries of a healing complication, but we promised you Creepy Accounts so we are delivering those to you RIGHT NOW! Starting with this episode, which is somewhat of a part 2 to TBB 63: Shared Death Experiences , while also being a Part 1 to next week's Creepy Account Episode where we focus on all of your Christmas Creepy Accounts!! As we explained in the intro, we wanted to give you both of these episodes since we specifically requested them as soon as possible and this is the course of action we have decided on! Thank you so much to everyone who trusted us with their stories and submitted them! If you have a Creepy Account of your own you would like to submit (anything paranormal, supernatural, scary, sweet or even a crime account) please send those to us in one of the three following ways: EMAIL THEM TO CREEPSANDCRIMES.CA@GMAIL.COM THE PORTAL ON OUR WEBSITE CREEPSANDCRIMESPODCAST.COM OR OUR REDDIT PAGE r/CreepsandCrimes with the Creepy Account Flag Love you all so much, talk to you on Tuesday for Naughty Or Nice List Confession Files TBB 64 and then again on CHRISTMAS DAY for our Christmas Creepy Accounts!! Need to Call Susan (Angel Wings and Healing Things)? Text Ellen at 704-562-3476 to book!! Make sure to tell her we sent you for a Besties only Special discount!! If you have a Creepy Account of your own you would like to submit, you can go to our Reddit (CreepsandCrimes) or email it to us at CREEPSANDCRIMES.CA@GMAIL.COM Creeps and Crimes Merch: ⁠⁠https://creepsandcrimesmerch.com/⁠⁠ Join our OG Pick Me Cult (Patreon): ⁠⁠https://patreon.com/creepsandcrimes⁠⁠ SUBSCRIBE AND SUPPORT WHEREVER YOU GET YOUR PODCASTS: - Apple Podcast: ⁠⁠https://podcasts.apple.com/us/podcast/creeps-and-crimes/id1533194848⁠⁠ - Spotify: ⁠⁠https://open.spotify.com/show/0v2kntCCfdQOSeMNnGM2b6?si=bf5c137913dd4af7⁠⁠ - Youtube: ⁠⁠https://youtube.com/@creepsandcrimespodcast?si=e6Lwuw6qvsEPBHzG⁠⁠ Business Inquiries please contact Management: ⁠⁠maggie@MRHentertainment.com⁠⁠ FOLLOW US ON SOCIALS: Creeps and Crimes Podcast - Insta: ⁠⁠https://www.instagram.com/creepsandcrimespodcast/?hl=en⁠⁠ - Facebook: ⁠⁠https://www.facebook.com/creepsandcrimespodcast/⁠⁠ - TikTok: ⁠⁠https://www.tiktok.com/@creepsandcrimes⁠⁠ Taylar Jane (True Crime Host) - Insta: @Taylarj - TikTok (True Crime Channel): @TaylarJane98 - TikTok (Personal): @TaylarJane1 Morgan Harris (Paranormal & Conspiracy Host) - Insta: @morgg.m - Tiktok: @morgg.m Want More Info? Check out our Website: ⁠⁠www.creepsandcrimespodcast.com⁠⁠ Send Us Mail & Fan Art to our PO Box!!! CREEPS AND CRIMES PODCAST PO BOX 11523 KNOXVILLE, TENNESSEE 37939 Have a Creepy Account You'd like to share and be featured on the Podcast? Email it to: ⁠⁠CreepsAndCrimes.CA@gmail.com⁠⁠ Submit it through the Portal on our Website (Listed above) or Post in on our Reddit Thread with the tag "creepy account" Love our TBB episodes and want to get in on the Action or submit an AIMS? Head over to our Reddit Community: @creepsandcrimes Need to contact us or request sources? Email us at ⁠⁠creepsandcrimespodcast@gmail.com Learn more about your ad choices. Visit podcastchoices.com/adchoices

We're back from a week of hanging out with rockstars in NYC. Not just figurative rockstars in the form of 25 DC BLACK members and Scott Heiferman of Meetup.com, but also literal rockstar Keith Murray of We Are Scientists. From “friendly” acquisitions to hiring frameworks and thoughts on leadership, this is what's top of mind for 7 and 8-figure location independent founders going into 2026. LINKS Meet location-independent founders inside Dynamite Circle (https://dynamitecircle.com/) Hang out exclusively with 7+ figure founders in DC BLACK (https://dynamitecircle.com/dc-black) Leader's Intent Framework (https://verticalperformance.us/develop-a-leaders-intent-to-transform-your-team/) Buy Back Your Time by Dan Martell (https://www.buybackyourtime.com/) TMBA 528: The Brenwall Code (https://tropicalmba.com/episodes/markbrenwall2) CHAPTERS (00:05:22) 7-Figures and Location Flexibility (00:09:25) The Rise of “Friendly” Business Acquisitions (00:14:12) What the Hell is Leadership? (00:18:45) Buying Back Your Time with AI & Hiring (00:22:40) Insights from Meetup.com's Scott Heiferman (00:28:10) Annual Planning: Working Backwards From the Goal (00:31:25) The Crossover Between Artist and Entrepreneur (00:39:46) Overcoming Challenges Through Innovation (00:42:47) Rebranding “Asking for Help” CONNECT: Dan@tropicalmba.com Ian@tropicalmba.com Past guests on TMBA include Cal Newport, David Heinemeier Hannson, Seth Godin, Ricardo Semler, Noah Kagan, Rob Walling, Jay Clouse, Einar Vollset, Sam Dogan, Gino Wickam, James Clear, Jodie Cook, Mark Webster, Steph Smith, Taylor Pearson, Justin Tan, Matt Gartland, Ayman Al-Abdullah, Lucy Bella. PLAYLIST: Don't Write Another Landing Page Without This Framework (https://tropicalmba.com/episodes/2026-email-funnels-playbook) [2026 Email Funnels Playbook] 6-Figure Sales Expert Calls You Out (https://tropicalmba.com/episodes/dont-keep-doing-this-2026) [Don't Keep Doing This in 2026] Your 2026 Business Plan in 36 Minutes (https://tropicalmba.com/episodes/2026-business-plan) [FREE Resource]

This week President Trump's director of the Office of Management and Budget announced that a major climate research centre would be broken up. 2025 has brought a wave of reorganisations and funding cuts, reshaping the ways science is done in the USA. Veteran science journalist Roland Pease tells us whether we're starting to see the impacts.Victoria Gill gets a subterranean tour of Finland's new nuclear waste disposal facility. It's the first country in the world to get one and the UK are interested in learning how they did it. Victoria is also joined by science journalist Caroline Steel to talk about this week in science research.And 40 years ago, Dian Fossey was murdered at her home in Rwanda where she had spent decades studying mountain gorillas. Gilly Forrester, Professor of Comparative Cognition at the University of Sussex talks about why the data collected from Dian's ‘gorillas in the mist' continues to shape science today.To discover more fascinating science content, head to bbc.co.uk search for BBC Inside Science and follow the links to The Open University.Presenter: Victoria Gill Producers: Clare Salisbury, Kate White and Tim Dodd Editor: Martin Smith Production Co-ordinator: Jana Bennett-Holesworth

In this info-packed episode, Dr. Linda Bluestein sits down with cardiologist Dr. Alexis Cutchins, an expert in pelvic venous disease (PVD) and POTS (postural orthostatic tachycardia syndrome), to tackle one of the most misunderstood vascular conditions in complex patients. From treatment options and expected outcomes to what really happens after embolization procedures, they unpack the physiology and the myths. Plus, they dive into GLP-1 medications like semaglutide and tirzepatide, long COVID symptom overlaps, heat intolerance, and why certain movement strategies backfire for patients with hypermobility, POTS, and other connective tissue conditions. They also trade tips on hydration, travel, pelvic support, and how to build movement back into your life, even when your nervous system fights you at every step. Takeaways: Dr. Cutchins explains how PVD impacts the whole body, causing fatigue, pelvic pain, and even mimicking other disorders. Weight loss drugs like semaglutide and tirzepatide can help, but only in the context of a larger strategy that considers joint instability, hormonal shifts, and gut function. They discuss how patients with PVD or dysautonomia are especially sensitive to warm environments and what that teaches us about blood flow and pressure regulation. From favorite exercises to subtle red flags, they explore how to reintroduce movement without triggering crashes or setbacks. Compression, salt loading, movement timing, and cooling tools can turn a nightmare trip into a manageable one. Want more Dr. Alexis Cutchins? https://www.instagram.com/drcutchins/ https://youtube.com/@DrCutchins?si=pNvR2A6eFOL4vS9m Want more Dr. Linda Bluestein, MD? Website: https://www.hypermobilitymd.com/ YouTube: https://www.youtube.com/@bendybodiespodcast Instagram: ⁠⁠⁠⁠https://www.instagram.com/hypermobilitymd/⁠⁠⁠⁠ Facebook: ⁠⁠⁠⁠https://www.facebook.com/BendyBodiesPodcast⁠⁠⁠⁠ X: ⁠⁠⁠⁠https://twitter.com/BluesteinLinda⁠⁠⁠⁠ LinkedIn: ⁠⁠⁠⁠https://www.linkedin.com/in/hypermobilitymd/⁠⁠⁠⁠ Newsletter: ⁠⁠⁠⁠https://hypermobilitymd.substack.com/ Shop my Amazon store ⁠⁠⁠ https://www.amazon.com/shop/hypermobilitymd Dr. Bluestein's Recommended Herbs, Supplements and Care Necessities: https://us.fullscript.com/welcome/hypermobilitymd/store-start Thank YOU so much for tuning in. We hope you found this episode informative, inspiring, useful, validating, and enjoyable. Join us on the next episode for YOUR time to level up your knowledge about hypermobility disorders and the people who have them. Join YOUR Bendy Bodies community at ⁠⁠https://www.bendybodiespodcast.com/⁠⁠. YOUR bendy body is our highest priority!⁠⁠ Learn more about Human Content at ⁠⁠⁠http://www.human-content.com⁠⁠⁠ Podcast Advertising/Business Inquiries: ⁠⁠⁠sales@human-content.com⁠⁠⁠ Part of the Human Content Podcast Network FTC: This video is not sponsored. Links are commissionable, meaning I may earn commission from purchases made through links Learn more about your ad choices. Visit megaphone.fm/adchoices

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Send us a textAbout Dr. Cheryl Chapman:Dr. Cheryl Chapman, OD, FIAOMC, FAAO, Diplomate ABOVice-President Board of Directors, American Academy of Orthokeratology and Myopia Control (AAOMC)Dr. Chapman works in private practice in Gretna, Nebraska.  She has instituted a full scope myopia management clinic within her practice and works tirelessly at spreading myopia management knowledge.  In addition to working one-on-one with doctors to implement practice protocols, she lectures within the optometric community as well as to local pediatricians and ophthalmologists.  Serving as an Adjunct Assistant Professor at the University of the Incarnate Word Rosenberg School of Optometry, Dr. Chapman also enjoys working closely in training 4th year extern students in current myopia management strategies.  She is a graduate of the University of Houston College of Optometry.----If you're considering or have ever considered getting a virtual team member for your practice check out hiredteem.com, mention The Myopia Podcast when signing up for a $250 dollar discount off of your first month's teem member.https://hireteem.com/myopia-podcast/

Send us a textAbout Dr. Kathryn Richdale:Dr. Kathryn Richdale received her BS from the University of Notre Dame and her OD, PhD, and Cornea and Contact Lens Advanced Practice Fellowship from The Ohio State University. She was founding director of the Clinical Vision Research Center, and established the Myopia Control Clinic at the State University of New York College of Optometry before joining the University of Houston College of Optometry (UHCO) as an Associate Professor in 2017. Dr. Richdale is an attending in the Cornea and Contact Lens Service, oversees the Myopia Management Service, and teaches in both the optometric and graduate programs at UHCO. She conducts research and teaches primarily in the areas of cornea, contact lenses and refractive error. Dr. Richdale earned her Diplomate in the American Academy of Optometry Cornea, Contact Lenses and Refractive Technologies section in 2019 and is currently a board member for our Academy's journal (OVS) and Foundation.---If you're considering or have ever considered getting a virtual team member for your practice check out hiredteem.com, mention The Myopia Podcast when signing up for a $250 dollar discount off of your first month's teem member.https://hireteem.com/myopia-podcast/

Debt is a very powerful tool, and often we are socialized to believe that debt is bad and being debt-free is good, and that's actually not true.In this episode, I'm sharing the difference between wealthy debt and broke debt, why the world's largest companies almost always have debt on their balance sheets, and how debt can either accelerate your growth or become a huge downfall if you don't know how to use it properly.Tune in to learn:Why debt itself isn't bad, and why being debt-free isn't always betterThe difference between how wealthy people and broke people think about debtHow debt can be used to create future growth, or rob your future selfThe few things you must understand to use debt powerfully, especially during high-spend seasons

Welcome back to the Oncology Brothers podcast! In this episode, we continue the CME series on HER2-positive GEJ and gastric cancer, shifting focus to the essential topic of treatment toxicity management. We're joined by two leading experts: Dr. Geoffrey Ku from Memorial Sloan Kettering and Dr. Shruti Patel from Stanford University. Building on their previous discussion of upper GI treatment algorithm with Dr. Rutika Mehta, this episode delves into the practical realities of managing patients on complex regimens. Drs. Ku & Patel break down the side effect profiles across the treatment continuum—from frontline trastuzumab-based combinations to emerging therapies like zanidatamab—and provide actionable strategies for community oncologists. Episode Highlights: • Practical management of frontline side effects with FOLFOX/XELOX chemotherapy plus trastuzumab and pembrolizumab • Reality check on trastuzumab cardiotoxicity: incidence rates and monitoring protocols in gastric vs. breast cancer • Immune-related adverse events with checkpoint inhibitors: what's common vs. rare in GI cancers • Critical insights on zanidatamab's synergistic diarrhea toxicity and mandatory prophylaxis strategies • TDXd (Enhertu) in second-line: moving beyond ILD fears to address frequent cytopenias and marrow management • Expert consensus on infusion reaction management for novel biologics • The importance of managing baseline symptoms in patients with dysphagia and nausea This episode bridges the gap between trial data and clinical practice, offering real-world wisdom on keeping patients on effective therapies through proactive toxicity management. Follow us on social media: •⁠  ⁠X/Twitter: https://twitter.com/oncbrothers •⁠  ⁠Instagram: https://www.instagram.com/oncbrothers •⁠  Website: https://oncbrothers.com/ Don't forget to subscribe for our complete CME series covering treatment algorithms, FDA approvals, and practical management strategies! Accreditation/Credit Designation Physicians' Education Resource®, LLC is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Physicians' Education Resource®, LLC designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Acknowledgment of Commercial Support This activity is supported by an educational grant from Jazz Pharmaceuticals, Inc. Link to gain CME credits from this activity: https://www.gotoper.com/courses/navigating-the-adverse-event-landscape-in-her2-gea-therapy

Something New!  For HR teams who discuss this podcast in their team meetings, we've created a discussion starter PDF to help guide your conversation. Download it here http://goodmorninghr.com/wp-content/uploads/2025/12/Good-Morning-HR-Episode-231-Discussion-Starter.pdf  In episode 231, Coffey talks with Diondra Filicetti about the real economics of employee engagement and how leaders can drive performance by shaping environment, alignment, and activation on their teams.  They discuss why engagement is an economic lever rather than a feel-good metric; how misaligned leadership expectations undermine performance; the impact of poorly prepared managers on engagement; practical ways to evaluate team capacity before adding headcount; the critical role of culture, trust, and behavior norms in workplace performance; strategies for designing the right environment, role alignment, and activation for teams; the Pygmalion Effect and how leaders' beliefs shape outcomes; diagnosing attitude issues versus structural problems; and using engagement needs as a framework for one-to-ones and organizational improvement.  You can find Diondra's book “Engagement Economics: Increasing Performance & Profitability by Engaging Your People” here https://a.co/d/9mTuXIs  Good Morning, HR is brought to you by Imperative—Bulletproof Background Checks. For more information about our commitment to quality and excellent customer service, visit us at https://imperativeinfo.com.   If you are an HRCI or SHRM-certified professional, this episode of Good Morning, HR has been pre-approved for half a recertification credit. To obtain the recertification information for this episode, visit https://goodmorninghr.com.   About our Guest:  Diondra Filicetti is a Learning and Development professional, best-selling author, and two-time TEDx speaker. As the founder of Driven By Co., she helps organizations enhance performance through engaging workshops, leadership programs, and communication training. Her book Engagement Economics explores how employee engagement drives profitability and success. With expertise in adult learning and instructional design, Diondra has empowered professionals to lead with purpose, connect effectively, and inspire growth.  Diondra Filicetti can be reached at https://www.drivenbyco.com  https://www.linkedin.com/in/diondrafilicetti  https://www.facebook.com/DrivenByCo  http://instagram.com/drivenbyco  https://www.youtube.com/@drivenbyco Her book “Engagement Economics: Increasing Performance & Profitability by Engaging Your People”  https://a.co/d/9mTuXIs  About Mike Coffey:  Mike Coffey is an entrepreneur, licensed private investigator, business strategist, HR consultant, and registered yoga teacher. In 1999, he founded Imperative, a background investigations and due diligence firm helping risk-averse clients make well-informed decisions about the people they involve in their business. Imperative delivers in-depth employment background investigations, know-your-customer and anti-money laundering compliance, and due diligence investigations to more than 300 risk-averse corporate clients across the US, and, through its PFC Caregiver & Household Screening brand, many more private estates, family offices, and personal service agencies. Imperative has been named a Best Places to Work, the Texas Association of Business' small business of the year, and is accredited by the Professional Background Screening Association.  Mike shares his insight from 25+ years of HR-entrepreneurship on the Good Morning, HR podcast, where each week he talks to business leaders about bringing people together to create value for customers, shareholders, and community. Mike has been recognized as an Entrepreneur of Excellence by FW, Inc. and has twice been recognized as the North Texas HR Professional of the Year.  Mike serves as a board member of a number of organizations, including the Texas State Council, where he serves Texas' 31 SHRM chapters as State Director-Elect; Workforce Solutions for Tarrant County; the Texas Association of Business; and the Fort Worth Chamber of Commerce, where he is chair of the Talent Committee. Mike is a certified Senior Professional in Human Resources (SPHR) through the HR Certification Institute and a SHRM Senior Certified Professional (SHRM-SCP). He is also a Yoga Alliance registered yoga teacher (RYT-200) and teaches multiple times each week. Mike and his very patient wife of 28 years are empty nesters in Fort Worth.  Learning Objectives: Understand and explains the economic impact of employee engagement. Identify gaps in environment, alignment, and activation that reduce team performance. Apply practical leadership behaviors that build trust, clarify purpose, and elevate team capacity. 

In this episode of the PFC Podcast, Dennis and Max delve into the complexities of managing shock, particularly hemorrhagic shock, in trauma patients. They discuss the importance of mental status as a key indicator of a patient's condition, the critical role of early intervention, and the protocols surrounding massive transfusions. The conversation also covers the use of TXA and calcium in resuscitation, emphasizing the need for careful monitoring and resource management in trauma situations. Max shares insights from his experience, highlighting the necessity of adapting protocols to the realities of field medicine.TakeawaysMental status changes in trauma patients indicate hemorrhage until proven otherwise.Calcium is essential in trauma care and should be administered with blood transfusions.Early intervention is crucial to prevent patients from deteriorating further.Massive transfusion protocols should be activated based on specific criteria.TXA can be beneficial in managing hemorrhagic shock but should be administered carefully.Resource management is vital in trauma situations, especially in combat settings.Understanding the physiological responses of trauma patients can guide treatment decisions.Training should emphasize the importance of mental status assessment in trauma care.Calcium administration can significantly impact patient outcomes during resuscitation.Protocols should be flexible to adapt to the unique challenges of each trauma case.Chapters00:00 Introduction to Shock and Its Stages02:52 Understanding Mental Status in Trauma Patients05:41 The Importance of Mental Status in Trauma Assessment08:37 Trigger Points for Blood Transfusion11:50 Massive Transfusion Protocols Explained14:51 Risk-Benefit Analysis of Early Blood Transfusion17:41 Resource Allocation in Trauma Situations33:07 Resource Constraints in Trauma Care35:51 Tissue Management in Critical Situations38:17 The Dilemma of Treatment Decisions39:36 Crystalloids vs. Blood in Resuscitation48:10 The Role of TXA in Hemorrhagic Shock57:32 Calcium's Importance in Trauma Resuscitation01:00:42 Understanding Calcium Leaching Mechanisms01:10:01 Calcium Administration in Trauma Care01:19:21 Innovations in Blood Resuscitation PracticesFor more content, go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.prolongedfieldcare.org⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Consider supporting us: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠patreon.com/ProlongedFieldCareCollective⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ or ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.lobocoffeeco.com/product-page/prolonged-field-care⁠

Southwest Michigan's Morning News podcast is prepared and delivered by the WSJM Newsroom. For these stories and more, visit https://www.wsjm.com and follow us for updates on Facebook. See omnystudio.com/listener for privacy information.

Why do high-achievers feel perpetually behind, even while consuming more content than ever? In this conversation, Pat Flynn explains the trap of “overlearning” and how it quietly keeps us stuck in motion without progress. You'll learn how to shift from “just-in-case” learning to “just-in-time” learning, create real momentum with a simple four-step framework, and protect what matters most with practical boundaries. Along the way, Pat shares how these principles helped him build multiple successful businesses (including a Pokémon channel with millions of followers) without sacrificing his family, health, or joy.Memorable Quotes“We all, in a way, are not just our overlearning, but we're getting over-inspired. We're so connected with so many amazing people out there who teach us this and push us over here, and then we're pulled over this way. We're spread so thin it's we're we're not seeing any results in our own life.”“Now we all have access to all the same kind of information, but we're still treating it as if it's scarce…However, we now live in a buffet line of information… and we're not quite evolved to absorb all of this because we're stuffing our plates full. Not only are we getting bloated and and and slowed down, but we're also getting force-fed on these platforms.”“This is the difference between ‘just-in-case learning,' which is what we've all been doing, and ‘just-in-time learning,' which is learning what you need to know to just take that next step. Because truly the action of taking that next step, the results of that one way or another—whether there are good results or bad results—can teach you so much more than just absorbing this information and never taking any action at all.” “[Silence] allows me to be with myself and to digest the things that I've already learned, to think about my priorities and the things I've already committed to. It allows me to make creative connections between things that I have already picked up instead of just getting more puzzle pieces to try to figure out where they go.”“I mean I was always taught that again, ‘The more you know the more successful you'll be,' and there's always seemingly opportunities to inject more of that learning. And it has this sort of fake productivity that goes along with it, because it is only truly productive, in my opinion, when you actually put into action those things that you do read or listen to or watch.”“At our authors retreat, a theme across most of the people there was not optimizing for revenue, not optimizing for scale, but optimizing for peace. And that was huge to think about.”“If I give myself five months to learn, I'm gonna take five months to learn it. If I give myself five hours to learn, I'm gonna take five hours to learn it. So I almost use time as a tool to help me get to the point of action and then understanding sooner.”“I've developed this rule called the 20% Itch Rule, and that is, out of all the things you do, 80% of your time is dedicated to the things you've already committed to, the things that, the responsibilities you have, the things that you've already said, yes to. The last 20% of time, allocate for curiosity, for play, for experimentation.”Key TakeawaysOverlearning Is a Hidden Productivity Trap. Constant consumption creates a sense of progress without producing results—and often adds more “to-dos” than your life can hold.Shift from “Just-in-Case” to “Just-in-Time.” Learn only what you need for the next step, then take action. Real learning accelerates through doing.Use the 4-Step Lean Learning Cycle. Identify the next step → choose one resource → implement → review. Repeat.Silence Helps You Digest What You Already Know. Pat's “silent car” habit creates space for integration, creativity, and clarity.Watch for “Junk Sparks.” Many ideas are just distractions dressed up as opportunity—especially when algorithms reduce the friction to buy, click, or binge.Try the “20% Itch Rule.” Dedicate 80% of your time to current commitments and responsibilities, and reserve 20% for curiosity, experimentation, and play—without blowing up your life.Optimize for Peace, Not Scale. More revenue isn't always worth the hidden cost. A Double Win means there's still room for what makes you feel most alive.ResourcesSmart Passive Income (Pat's Business)Superfans (Book)Lean Learning (Book)Watch on YouTube at:  https://youtu.be/aLp6hHTrYQsThis episode was produced by Sarah Vorhees Wendel of VW Sound

Bill presents with early-stage amyotrophic lateral sclerosis (ALS) and reports mild lower extremity weakness and occasional tripping when walking on uneven surfaces. Which intervention is MOST appropriate to address his current functional mobility?A) Prescribe a wheelchair for energy conservationB) Provide ankle-foot orthoses (AFOs) to prevent foot dropC) Initiate high-intensity strength training for lower extremitiesD) Recommend a walker to improve stabilityJoin the FREE Facebook Group: www.nptegroup.com

This week on Sinica, I speak with Mark Sidel, the Doyle Bascom Professor of Law and Public Affairs at the University of Wisconsin-Madison and a senior fellow at the International Center for Not for Profit Law. Mark has written extensively on law and philanthropy in China and across Asia, including widely cited analyses of how the Chinese security state came to play a central role in managing foreign civil society organizations. Since the Law on the Management of Domestic Activities of Overseas NGOs took effect on January 1, 2017, China has introduced a remarkably comprehensive, vertically integrated system of oversight for foreign NGOs, foundations, and nonprofits.We discuss how this system combines securitization and political risk management with selective accommodation of service provision and technical expertise, Mark's typology of organizational responses (survivors, hibernators, regionalizers, work-arounders, and leavers), the requirement that foreign NGOs secure professional supervisory units, the impact on China's domestic nonprofit ecosystem, and what this tells us about the party-state's long-term vision for controlled engagement with the outside world.4:43 – The landscape of non-state organizations before the 2016 law 7:06 – What changed: color revolutions, Arab Spring, and domestic anxieties 9:08 – Public security intellectuals and their influence on the law 11:51 – How registration and temporary activity filing systems work in practice 13:48 – Why the Ministry of Public Security, not Civil Affairs, was put in charge 19:31 – The professional supervisory unit requirement and dependency relationships22:48 – How the state shifted foreign NGO work away from advocacy without banning it26:17 – Mark's typology: survivors, hibernators, regionalizers, work-arounders, and leavers 35:19 – What correlates with success for those who have survived 40:41 – Impact on China's domestic nonprofit ecosystem and professional intermediaries 45:54 – What makes China's system distinctive compared to India, Egypt, Russia, and Vietnam 50:19 – The Article 53 problem and university partnerships 55:32 – Advice for mid-sized foundations or NGOs considering work in China todayPaying it Forward: Neysun Mahboubi and the Penn Project on the Future of U.S.-China RelationsRecommendations:Mark: Everyday Democracy: Civil Society, Youth, and the Struggle Against Authoritarian Culture in China by Anthony SpiresKaiser: The music of Steve Morse (Dixie Dregs, The Dregs, Steve Morse Band)See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What makes humans so predictably irrational? Nobel Laureate Richard Thaler and Alex Imas join Guy Kawasaki to reveal the quirks that shape our decisions—from golf greens to stock markets. Drawing from their new book, The Winner's Curse: Then and Now, they revisit the field they helped pioneer: behavioral economics. This episode is a masterclass in understanding why the smartest people make the strangest choices—and how awareness turns mistakes into wisdom.---Guy Kawasaki is on a mission to make you remarkable. His Remarkable People podcast features interviews with remarkable people such as Jane Goodall, Marc Benioff, Woz, Kristi Yamaguchi, and Bob Cialdini. Every episode will make you more remarkable.With his decades of experience in Silicon Valley as a Venture Capitalist and advisor to the top entrepreneurs in the world, Guy's questions come from a place of curiosity and passion for technology, start-ups, entrepreneurship, and marketing. If you love society and culture, documentaries, and business podcasts, take a second to follow Remarkable People.Listeners of the Remarkable People podcast will learn from some of the most successful people in the world with practical tips and inspiring stories that will help you be more remarkable.Episodes of Remarkable People organized by topic: https://bit.ly/rptopologyListen to Remarkable People here: **https://podcasts.apple.com/us/podcast/guy-kawasakis-remarkable-people/id1483081827**Like this show? Please leave us a review -- even one sentence helps! Consider including your Twitter handle so we can thank you personally!Thank you for your support; it helps the show!See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Every time a team member asks for a raise, the pressure is instant — but it doesn't have to be. In this episode, find out how to talk money with your team, set clear expectations, and lead raise conversations without it getting awkward. We explore inflation, bonuses, and systems that give your team a clear path for growth without blowing up your payroll. Listen now to take the stress out of every raise decision!Topics discussed:The trap of throwing money at problemsMistakes owners make when asked for a raiseHenry's dental assistant ladder and pay scaleHow to avoid losing team members when you say “no”How bonuses impact pay decisionsHow to handle the inflation and market pay argumentHow to stay competitive and keep team members happyThis episode was produced by Podcast Boutique https://www.podcastboutique.comeamsGet Free DPH Trainings,  Download the App and Join our Community!  CLICK HERE GRAB THE FREE PLAYBOOK HERE - Discover 30 proven strategies top-performing dentists use to increase profits, cut clinical days, and finally enjoy the freedom they originally built their practices for.https://www.dentalpracticeheroes.com/playbook Check out www.relevanceonlinemarketing.com if you want to get the same great marketing results as Dr. Etch.  Mention DPH and get your first month FREE!Take Control of Your Practice and Your Life We help dentists take more time off while making more money through systematization, team empowerment, and creating leadership teams. Ready to build a practice that works for you? Visit www.DentalPracticeHeroes.com to learn more.

In this episode of The Brain Vault Podcast, Larry sits down with Louisa Loran, leadership advisor and author of Leadership, Autonomy and Motion, for a conversation that redefines how leaders create change. Not through more programs or strategies—but through behavior, presence, and motion. Louisa shares why listening creates movement, why autonomy unlocks momentum, and why clarity matters even when the path isn't fully visible. Together, she and Larry explore how small shifts in how you show up can create meaningful change. If you're ready for leadership that's human and adaptive—this conversation will stay with you.

How do you go from seven employees to seven figures 11 years? Heather Piselli, Aliscia Martinelli and Monica Rivera did it together. They're co-owners of Privé Salon Co., with three comission salon locations and a suite rental facility in the Phildelphia metro area. The also co-host the GoHam podcast, featuring unfiltered conversations on business, leadership, and the beauty industry.On this episode, Blake is joined by Healther, Alisica, and Monica; and their Summit salon coach, Kierstin Nemer, who's been at their side throughout the journey. Yes this is the most guests we've ever had on a single episode -- but the conversation really demonstrates how each team member plays to her strenghts! You'll hear about their strategies for hiring, taking risks, growing service providers, and why the phrase "Go Ham" describes their business ethos.    Follow Summit Salon Business Center on Instagram @SummitSalon, and on TikTok at SummitSalon. SUMM IT UP is now on YouTube! Watch extended cuts of our interviews at www.youtube.com/@summitunlockedFind host Blake Reed Evans on Instagram @BlakeReedEvans and on TikTok at blakereedevans. His DM's are always open! You can email Blake at bevans@summitsalon.com. Visit us at SummitSalon.com to connect with others in the industry.

Join endocrinology experts Sara MacLeod and Shannon Idzik as they explore the science and strategy behind effective obesity care, offering practical, evidence-based insights clinicians can apply right away. From navigating treatment options like lifestyle interventions, medications and surgery to fostering stigma-free, patient-centered conversations, this episode delivers real tools for improving outcomes. Whether you're new to obesity management or looking to enhance your clinical approach, this discussion will inspire confidence and compassion in your practice. Objectives Evaluate clinical trial data providing evidence for the current obesity treatment landscape. Examine the pharmacotherapies for treatment of obesity. Summarize lifestyle factors and behavior change options available for people living with obesity, addressing stigma and bias. Develop a treatment plan for patients living with obesity that addresses their individual comorbidities, clinical risks and personal goals. Learners may claim CE credit for this program through Dec. 31, 2026, by participating in the full multi-module Clinical Advantage: Endocrinology Certificate for Advanced Practice Providers program available here. A participation code will be provided at the end of the podcast — make sure to write this code down. Once you have listened to the podcast and have the participation code, return to this activity in the AANP CE Center. Click on the "Next Steps" button of the activity and: Enter the participation code that was provided. Complete the posttest. Complete the other modules of the Clinical Advantage: Endocrinology Certificate for Advanced Practice Providers program. Complete the overall program evaluation. This activity is supported by independent educational grants from Ascendis Pharma Inc., Novo Nordisk Inc., and Xeris Pharmaceuticals, Inc.

SummaryIn this episode of the PPC Live podcast, host Anu Adegbola speaks with Nadia Mursal about the importance of learning from mistakes in the digital marketing industry. They discuss Nadia's personal experiences with account restructuring, the significance of strong client relationships, and the role of management in fostering a supportive team culture. The conversation highlights common mistakes in PPC, particularly around tracking performance, and offers practical advice for handling errors effectively. Nadia emphasizes the need for open communication and collaboration within teams, ultimately advocating for a positive work environment that encourages growth and learning.Takeaway:TakeawaysMistakes are opportunities for learning and growth.Building strong client relationships is crucial for success.Management should foster a supportive environment for team members.Tracking performance is essential for effective PPC campaigns.Open communication can prevent issues from escalating.Treat team members with respect and understanding.Encourage a culture of collaboration and knowledge sharing.Mistakes should be approached as a team effort, not individual blame.A positive work culture leads to better performance and loyalty.Always be open to feedback and continuous improvement.Chapters00:00 Introduction to Nadia Mursal and PPC Live02:57 Nadia's Journey in Digital Marketing05:58 Learning from Mistakes in Digital Marketing08:50 Client Relationships and Accountability11:40 The Role of Managers in Mistake Management14:39 Creating a Supportive Team Culture17:44 Innovative Approaches to Team Development21:04 Navigating Client Expectations and Mistakes23:59 Embracing Mistakes as Learning Opportunities25:32 Common Industry Mistakes: The Importance of Tracking30:51 Creating a Supportive Team Culture35:45 Treating People with Respect and Understanding43:29 Outro.mp3Follow Nadia on LinkedInPPC Live The Podcast features weekly conversations with paid search experts sharing their experiences, challenges, and triumphs in the ever-changing digital marketing landscape.Upcoming: ⁠⁠⁠⁠PPC Live event⁠⁠⁠⁠, February 5th, 2026 at StrategiQ's London offices (where Dragon's Den was filmed!) featuring Google Ads script master Nils Rooijmans.Follow us on ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow us on ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Join our ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Whatsapp group - https://bit.ly/pluwhatsappSubscribe to our ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Newsletter - https://ppc.live/newsletter-sign-up/

A Burglar's Christmas by Willa Cather w/Tom Libby---00:00 - Welcome and Introduction - A Burglar's Christmas by Willa Cather.04:25 - Opening A Burglar's Christmas by Willa Cather.08:21 - Willa Cather Wrote at the Crossroads of Modernity.12:43 - Setting Goals and the Vagaries of New Year's Resolutions.18:01 - Check Out Jesan's Time Management Training Videos on YouTube. 25:24 - Joan Didion, Virginia Woolf, and What We Don't Say About the Patriarchy. 31:13 - Leaders Avoid Hiding in the Word Salad. 32:47 - Willa Cather's Story, with Hunger and Envy. 42:12 - Seinfeld's "The Strike," Festivus and The Death of Black Friday.45:04 - Societal Grievances, Commercialism, and Festive Celebration. 51:55 - Leaders Provide the Freedom to Voice Grievances without Repercussions.01:02:13 - Nietzsche, Cather, and the Myth of Eternal Return.01:06:14 - Millennials, Gen-Zers, and Gen X-ers.01:13:10 - The Potential of the Internet Needs to be Reconsidered.  01:20:47 - Drivers For Success When You Have Children vs. When You Don't Have Children 01:32:34 - Leaders Maintain a Consistent Culture on Teams.01:37:06 - Introspection and Goal Setting. 01:43:29 - Leaders Genuinely Care About People, Teams, and Success. 01:44:27 - Staying on the Leadership Path with A Burglar's Christmas by Willa Cather.---Opening and Closing theme composed by Brian Sanyshyn of Brian Sanyshyn Music.---Pick up your copy of 12 Rules for Leaders: The Foundation of Intentional Leadership NOW on AMAZON!Check out the 2022 Leadership Lessons From the Great Books podcast reading list!---Check out HSCT Publishing at: https://www.hsctpublishing.com/.Check out LeadingKeys at: https://www.leadingkeys.com/Check out Leadership ToolBox at: https://leadershiptoolbox.us/Contact HSCT for more information at 1-833-216-8296 to schedule a full DEMO of LeadingKeys with one of our team members.---Leadership ToolBox website: https://leadershiptoolbox.us/.Leadership ToolBox LinkedIn: https://www.linkedin.com/company/ldrshptlbx/.Leadership ToolBox YouTube: https://www.youtube.com/channel/UCJvVbIU_bSEflwYpd9lWXuA/.Leadership ToolBox Twitter: https://twitter.com/ldrshptlbx.Leadership ToolBox IG: https://www.instagram.com/leadershiptoolboxus/.Leadership ToolBox FB: https://www.facebook.com/LdrshpTlb ★ Support this podcast on Patreon ★

Clement Manyathela speaks to Dr Mike Masiapato, the Commissioner & CEO of the Border Management Authority about illegal entry attempts at the country’s borders and the authority’s festive season crackdown.See omnystudio.com/listener for privacy information.

WSJM Afternoon News for 12-17-25See omnystudio.com/listener for privacy information.

Chegou o episódio escolhido por vocês! Marcela Belleza e Joanne Alves convidam Carol Millon para conversar sobe 6 clinicagens de inibidores de SGLT2, as gliflozinas:Indicações além do DMRisco de CAD euglicêmicaQuando não usar?⁠Cuidados com doença aguda (sick day) e hipovolemia⁠Cuidados pré-operatórioRisco de fratura e amputaçãoReferências:1. Bailey CJ, et al. Dapagliflozin add-on to metformin in type 2 diabetes inadequately controlled with metformin: a randomized, double-blind, placebo-controlled 102-week trial. BMC Med. 2013;11:43. Published 2013 Feb 20. doi:10.1186/1741-7015-11-432. Bersoff-Matcha SJ, et al. Fournier Gangrene Associated With Sodium-Glucose Cotransporter-2 Inhibitors: A Review of Spontaneous Postmarketing Cases. Ann Intern Med. 2019;170(11):764-769. doi:10.7326/M19-00853. Chang HY, et al. Association Between Sodium-Glucose Cotransporter 2 Inhibitors and Lower Extremity Amputation Among Patients With Type 2 Diabetes. JAMA Intern Med. 2018;178(9):1190-1198. doi:10.1001/jamainternmed.2018.3034 4. Clar C, et al. Systematic review of SGLT2 receptor inhibitors in dual or triple therapy in type 2 diabetes. BMJ Open. 2012 Oct 18;2(5):e001007. doi: 10.1136/bmjopen-2012-001007. PMID: 23087012; PMCID: PMC3488745.5. Das SR, et al. 2020 Expert Consensus Decision Pathway on Novel Therapies for Cardiovascular Risk Reduction in Patients With Type 2 Diabetes: A Report of the American College of Cardiology Solution Set Oversight Committee. J Am Coll Cardiol. 2020 Sep 1;76(9):1117-1145. doi: 10.1016/j.jacc.2020.05.037. Epub 2020 Aug 5. PMID: 32771263; PMCID: PMC7545583. 6. Fralick M, et al. Risk of amputation with canagliflozin across categories of age and cardiovascular risk in three US nationwide databases: cohort study. BMJ. 2020;370:m2812. Published 2020 Aug 25. doi:10.1136/bmj.m28127. Li D, et al. Urinary tract and genital infections in patients with type 2 diabetes treated with sodium-glucose co-transporter 2 inhibitors: A meta-analysis of randomized controlled trials. Diabetes Obes Metab. 2017;19(3):348-355. doi:10.1111/dom.128258. Neal B, et al. Rationale, design, and baseline characteristics of the Canagliflozin Cardiovascular Assessment Study (CANVAS)--a randomized placebo-controlled trial. Am Heart J. 2013;166(2):217-223.e11. doi:10.1016/j.ahj.2013.05.0079. Nyirjesy P, et al. Evaluation of vulvovaginal symptoms and Candida colonization in women with type 2 diabetes mellitus treated with canagliflozin, a sodium glucose co-transporter 2 inhibitor. Curr Med Res Opin. 2012;28(7):1173-1178. doi:10.1185/03007995.2012.69705310. Perkovic V, et al. Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy. N Engl J Med. 2019;380(24):2295-2306. doi:10.1056/NEJMoa181174411. Rosenwasser RF, et al. SGLT-2 inhibitors and their potential in the treatment of diabetes. Diabetes Metab Syndr Obes. 2013 Nov 27;6:453-67. doi: 10.2147/DMSO.S34416. PMID: 24348059; PMCID: PMC3848644.12. Sridharan K, Sivaramakrishnan G. Risk of limb amputation and bone fractures with sodium glucose cotransporter-2 inhibitors: a network meta-analysis and meta-regression. Expert Opin Drug Saf. 2025;24(7):797-804. doi:10.1080/14740338.2024.237775513. Ueda P,  et al. Sodium glucose cotransporter 2 inhibitors and risk of serious adverse events: nationwide register based cohort study. BMJ. 2018;363:k4365. Published 2018 Nov 14. doi:10.1136/bmj.k436514. Watts NB, et al. Effects of Canagliflozin on Fracture Risk in Patients With Type 2 Diabetes Mellitus. J Clin Endocrinol Metab. 2016 Jan;101(1):157-66. doi: 10.1210/jc.2015-3167. Epub 2015 Nov 18. PMID: 26580237; PMCID: PMC4701850.15. Zhuo M, et al. Association of Sodium-Glucose Cotransporter-2 Inhibitors With Fracture Risk in Older Adults With Type 2 Diabetes. JAMA Netw Open. 2021;4(10):e2130762. Published 2021 Oct 1. doi:10.1001/jamanetworkopen.2021.3076216. Emerson Cestari Marino, Leandra Anália Freitas Negretto, Rogério Silicani Ribeiro, Denise Momesso, Alina Coutinho Rodrigues Feitosa, Marcos Tadashi Kakitani Toyoshima, Joaquim Custódio da Silva Junior, Sérgio Vencio, Marcio Weissheimer Lauria, João Roberto de Sá, Domingos A. Malerbi, Fernando Valente, Silmara A. O. Leite, Danillo Ewerton Oliveira Amaral, Gabriel Magalhães Nunes Guimarães, Plínio da Cunha Leal, Maristela Bueno Lopes, Luiz Carlos Bastos Salles, Liana Maria Torres de Araújo Azi, Amanda Gomes Fonseca, Lorena Ibiapina M. Carvalho, Francília Faloni Coelho, Bruno Halpern, Cynthia M. Valerio, Fabio R. Trujilho,  Antonio Carlos Aguiar Brandão, Ruy Lyra e Marcello Bertoluci. Rastreamento e Controle da Hiperglicemia no Perioperatório – Posicionamento Conjunto da Sociedade Brasileira de Diabetes (SBD), Sociedade Brasileira de Anestesiologia (SBA) e Associação Brasileira para o Estudo da Obesidade e Síndrome Metabólica (ABESO). Diretriz Oficial da Sociedade Brasileira de Diabetes (2025). DOI: 10.29327/5660187.2025-10 , ISBN: 978-65-5941-367-6.17. Singh LG, Ntelis S, Siddiqui T, Seliger SL, Sorkin JD, Spanakis EK. Association of Continued Use of SGLT2 Inhibitors From the Ambulatory to Inpatient Setting With Hospital Outcomes in Patients With Diabetes: A Nationwide Cohort Study. Diabetes Care. 2024;47(6):933-940. doi:10.2337/dc23-112918. Mehta PB, Robinson A, Burkhardt D, Rushakoff RJ. Inpatient Perioperative Euglycemic Diabetic Ketoacidosis Due to Sodium-Glucose Cotransporter-2 Inhibitors - Lessons From a Case Series and Strategies to Decrease Incidence. Endocr Pract. 2022;28(9):884-888. doi:10.1016/j.eprac.2022.06.00619. Umapathysivam MM, Morgan B, Inglis JM, et al. SGLT2 Inhibitor-Associated Ketoacidosis vs Type 1 Diabetes-Associated Ketoacidosis. JAMA Netw Open. 2024;7(3):e242744. Published 2024 Mar 4. doi:10.1001/jamanetworkopen.2024.274420. Fleming N, Hamblin PS, Story D, Ekinci EI. Evolving Evidence of Diabetic Ketoacidosis in Patients Taking Sodium-Glucose Cotransporter 2 Inhibitors. J Clin Endocrinol Metab. 2020;105(8):dgaa200. doi:10.1210/clinem/dgaa20021. Neuen BL, Young T, Heerspink HJL, et al. SGLT2 inhibitors for the prevention of kidney failure in patients with type 2 diabetes: a systematic review and meta-analysis. Lancet Diabetes Endocrinol. 2019;7(11):845-854. doi:10.1016/S2213-8587(19)30256-622. Braunwald E. Gliflozins in the Management of Cardiovascular Disease. N Engl J Med. 2022;386(21):2024-2034. doi:10.1056/NEJMra211501123. Zinman B, Wanner C, Lachin JM, et al. Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes. N Engl J Med. 2015;373(22):2117-2128. doi:10.1056/NEJMoa150472024. Neal B, Perkovic V, Mahaffey KW, et al. Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes. N Engl J Med. 2017;377(7):644-657. doi:10.1056/NEJMoa161192525. Wiviott SD, Raz I, Bonaca MP, et al. Dapagliflozin and Cardiovascular Outcomes in Type 2 Diabetes. N Engl J Med. 2019;380(4):347-357. doi:10.1056/NEJMoa181238926. McMurray JJV, Solomon SD, Inzucchi SE, et al. Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction. N Engl J Med. 2019;381(21):1995-2008. doi:10.1056/NEJMoa191130327. Packer M, Anker SD, Butler J, et al. Cardiovascular and Renal Outcomes with Empagliflozin in Heart Failure. N Engl J Med. 2020;383(15):1413-1424. doi:10.1056/NEJMoa202219028. Anker SD, Butler J, Filippatos G, et al. Empagliflozin in Heart Failure with a Preserved Ejection Fraction. N Engl J Med. 2021;385(16):1451-1461. doi:10.1056/NEJMoa210703829. Heerspink HJL, Stefánsson BV, Correa-Rotter R, et al. Dapagliflozin in Patients with Chronic Kidney Disease. N Engl J Med. 2020;383(15):1436-1446. doi:10.1056/NEJMoa202481630. The EMPA-KIDNEY Collaborative Group, Herrington WG, Staplin N, et al. Empagliflozin in...

This year delivered whiplash: geopolitics, tariffs, and technology all shifting at once. And heading into 2026, the disruption isn't easing up. In this special episode, host Bob Safian distills five hard-won lessons from Rapid Response this year on how to lead when the ground won't stop moving. You'll hear standout moments from Brian Chesky, Clara Shih, Marc Lore, José Andrés, and more, with practical takeaways for turning uncertainty into advantage.Visit the Rapid Response website here: https://www.rapidresponseshow.com/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Welcome back to TBB aka The Bestie Bonus where our question of the week is What is a Family Secret or Lore that you are the Keeper of? Before getting into our Am I Missing Something? (AIMS) Segment, where a bestie asks us if she should go to her mom with a family secret she has been harboring... does she have a secret sibling somewhere in the world? Give your bestie some advice by commenting!! We will talk to you on Thursday for a very special SDE episode that we cannot wait to share with you!! LOVE YA BYE!! Thanks so much to our sponsor for Today's Episode: LIFEMD Get 50% off the LifeMD Weight Management Program plus free shipping—start your personalized plan online at https://lifemd.com/CREEPS. Need to Call Susan (Angel Wings and Healing Things)? Text Ellen at 704-562-3476 to book!! Make sure to tell her we sent you for a Besties only Special discount!! If you have a Creepy Account of your own you would like to submit, you can go to our Reddit (CreepsandCrimes) or email it to us at CREEPSANDCRIMES.CA@GMAIL.COM Creeps and Crimes Merch: ⁠⁠https://creepsandcrimesmerch.com/⁠⁠ Join our OG Pick Me Cult (Patreon): ⁠⁠https://patreon.com/creepsandcrimes⁠⁠ SUBSCRIBE AND SUPPORT WHEREVER YOU GET YOUR PODCASTS: - Apple Podcast: ⁠⁠https://podcasts.apple.com/us/podcast/creeps-and-crimes/id1533194848⁠⁠ - Spotify: ⁠⁠https://open.spotify.com/show/0v2kntCCfdQOSeMNnGM2b6?si=bf5c137913dd4af7⁠⁠ - Youtube: ⁠⁠https://youtube.com/@creepsandcrimespodcast?si=e6Lwuw6qvsEPBHzG⁠⁠ Business Inquiries please contact Management: ⁠⁠maggie@MRHentertainment.com⁠⁠ FOLLOW US ON SOCIALS: Creeps and Crimes Podcast - Insta: ⁠⁠https://www.instagram.com/creepsandcrimespodcast/?hl=en⁠⁠ - Facebook: ⁠⁠https://www.facebook.com/creepsandcrimespodcast/⁠⁠ - TikTok: ⁠⁠https://www.tiktok.com/@creepsandcrimes⁠⁠ Taylar Jane (True Crime Host) - Insta: @Taylarj - TikTok (True Crime Channel): @TaylarJane98 - TikTok (Personal): @TaylarJane1 Morgan Harris (Paranormal & Conspiracy Host) - Insta: @morgg.m - Tiktok: @morgg.m Want More Info? Check out our Website: ⁠⁠www.creepsandcrimespodcast.com⁠⁠ Send Us Mail & Fan Art to our PO Box!!! CREEPS AND CRIMES PODCAST PO BOX 11523 KNOXVILLE, TENNESSEE 37939 Have a Creepy Account You'd like to share and be featured on the Podcast? Email it to: ⁠⁠CreepsAndCrimes.CA@gmail.com⁠⁠ Submit it through the Portal on our Website (Listed above) or Post in on our Reddit Thread with the tag "creepy account" Love our TBB episodes and want to get in on the Action or submit an AIMS? Head over to our Reddit Community: @creepsandcrimes Need to contact us or request sources? Email us at ⁠⁠creepsandcrimespodcast@gmail.com Learn more about your ad choices. Visit podcastchoices.com/adchoices

In the ED, we regularly care for sick patients presenting acutely with abnormal vital signs, altered mental status, and end organ dysfunction. Oftentimes, the culprit ends up being sepsis, or overdose, or organ failure. But it is important that we consider rarer endocrine presentations like decompensated hypothyroidism. In this Part 1 of this two-part podcast with Dr George Willis and Dr Alyssa Louis, we answer questions like: Why is the term myxedema coma a misnomer and should be abandoned? How can we differentiate between sepsis or environmental hypothermia or toxidrome from decompensated hypothyroidism at the bedside? When is it appropriate to order a TSH, a T4 and T3? What are the most important life-threatening triggers that need to be addressed in patients with decompensated hypothyroidism? Why is it important to test for cortisol levels and consider stress-dose steroids in all patients with decompensated hypothyroidism? Why is endotracheal intubation particularly dangerous in decompensated hypothyroidsm? What is the best way to manage hypothermia? Why is the order of medications for treatment of decompensated hypothyroidism so important? and many more... Please consider a donation to EM Cases to ensure continuing Free Open Access Medical Education: https://emergencymedicinecases.com/donation/

In this episode, the CardioNerds (Dr. Natalie Tapaskar, Dr. Jenna Skowronski, and Dr. Shazli Khan) discuss the process of heart transplantation from the initial donor selection to the time a patient is discharged with Dr. Dave Kaczorowski and Dr. Jason Katz. We dissect a case where we understand criteria for donor selection, the differences between DBD and DCD organ donors, the choice of vasoactive agents in the post-operative period, complications such as cardiac tamponade, and the choice of immunosuppression in the immediate post-operative period. Most importantly, we highlight the importance of multi-disciplinary teams in the care of transplant patients. Audio editing for this episode was performed by CardioNerds Intern, Dr. Julia Marques Fernandes. Enjoy this Circulation 2022 Paths to Discovery article to learn about the CardioNerds story, mission, and values. CardioNerds Heart Success Series PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Pearls When thinking about donor selection, you need to consider how much physiologic stress your recipient can tolerate, and this may guide your selection of “higher risk” or “lower risk” donors.   The use of DCD donors has increased the potential donor pool and shortened waitlist times with very similar perioperative outcomes to DBD transplantation.  Post-operative critical care management rests on a fundamental principle to apply as much inotropic/vasoactive therapy as needed to achieve some reasonable physiologic hemostasis, and then getting “the heck out of the way!” There are no standard regimens as practices vary across centers, but rest on providing adequate RV support, maintaining AV synchrony, and early resuscitation.   The RV is fickle and doesn't take a joke too well. RV dysfunction post-transplant is important to watch for, and it can be transient or require aggressive support. Don't miss assessing for cardiac tamponade which can require surgical evacuation- “where there's space, that space can be filled with fluid.”   Induction immunosuppression post-transplant varies across centers, but some considerations for use may include (1) high sensitization of the patient, (2) high risk immunologic donor-recipient matching, and (3) recipient renal dysfunction to provide a calcineurin inhibitor (CNI) sparing regimen long term.  Management of heart transplant patients is a multi-disciplinary effort that requires coordination amongst heart failure/transplant cardiologists, cardiac surgeons, anesthesiologists, pathology/immunologists and a slew of ancillary services. Without a dynamic and collaborative team, successful cardiac transplantation could not be possible.  Notes Notes: Notes drafted by Dr. Natalie Tapaskar  What are the basic components of donor heart selection? In practicality, it can be a very inexact science, but we use some basic selection criteria such as: (1) size matching (2) ischemic time (3) donor graft function (4) immunologic compatibility (5) age of the potential donor and recipient (6) severity of illness of the recipient (7) regional variation in donor availability When thinking about accepting older donors (>50 years old), we ideally would screen for donor coronary disease and try to keep ischemic times as short as possible. We may accept an older donor for a recipient who is highly sensitized, which leaves a smaller potential donor pool. There is no clear consensus on size matching, but the predicted heart mass is most used. We are generally more comfortable oversizing than under-sizing donor hearts. Serial echocardiography is important in potential donors as initially reduced ejection fractions can improve on repeat testing, and these organs should not be disregarded automatically. For recipients who are more surgically complex, (i.e. multiple prior sternotomies or complex anatomy), it's probably preferable to avoid older donors with some graft dysfunction and favor donors with shorter ischemic times. What is the difference between DBD and DCD? DBD is donation after brain death- these donors meet criteria for brain death. Uniform Determination of Death Act 1980: the death of an individual is The irreversible cessation of circulatory and respiratory functions or The irreversible cessation of all functions of the entire brain, including those of the brain stem DCD is donation after circulatory death- donation of the heart after confirming that circulatory function has irreversibly ceased. Only donors in category 3 of the Maastricht Classification of DCD donors are considered for DCD donations: anticipated circulatory arrest (planned withdrawal of life-support treatment). DCD hearts can be procured via direct procurement or normothermic regional perfusion (NRP). The basic difference is the way the hearts are assessed, either on an external circuit or in the donor body. For the most complex recipient, DCD may not be utilized at some centers due to concern for higher rates of delayed graft function, but this is center specific and data is still evolving. What are some features surgeons consider when procuring the donor heart? Visual assessment of the donor heart is key in DBD or NRP cases. LV function may be hard to assess, but visually the RV can be inspected. Palpation of the coronary arteries is important to assess any calcifications or abnormalities. Ventricular arrhythmias at the time of procurement may be concerning. Key considerations in the procurement process: (1) Ensuring the heart remains decompressed at all times and doesn't become distended (2) adequate cardioplegia delivery (3) aorta is cross-clamped properly all the way across the vessel (4) avoiding injury to adjacent structures during procurement What hemodynamic parameters should we monitor and what vasoactive agents are used peri-heart transplant? There is no consensus regarding vasoactive agent use post-transplant and practice varies across institutions. Some commonly seen regimens may include: (1) AAI pacing around 110 bpm to support RV function and preserve AV synchrony (2) inotropic agents such as epinephrine and dobutamine to support RV function (3) pulmonary vasodilators such as inhaled nitric oxide to optimize RV afterload Early post-transplant patients tend to have low cardiac filling pressures and require preload monitoring and resuscitation initially. Slow weaning of inotropes as the patient shows signs of stable graft function and hemodynamics. RV dysfunction may manifest as elevated central venous pressure with low cardiac index or hypotension with reducing urine output. Optimize inotropic support, volume status, metabolic status (acidosis and hypoxia), afterload (pulmonary hypertension), and assess for cardiac tamponade. Tamponade requires urgent take-back to the operating room to evacuate material. Refractory RV failure requires mechanical circulatory support, with early consideration of VA-ECMO. Isolated RV MCS may be used in the right clinical context. Why do pericardial effusions/cardiac tamponade happen after transplant? They are not uncommon after transplant and can be due to: Inherent size differences between the donor and recipient (i.e. if the donor heart is much smaller than the recipient's original heart) Bleeding from suture lines and anastomoses, pacing wires, and cannulation sites Depending on the hemodynamic stability of the patient and the location of the effusion, these effusions may require urgent return to the OR for drainage/clot evacuation via reopening the sternotomy, mini thoracotomy, and possible pericardial windows. What are the basics of immunosuppression post-transplant? Induction immunosuppression is variably used and is center-specific. Considerations for using induction therapy may include: (1) high sensitization of the patient (2) younger patients or multiparous women with theoretically more robust immune systems (3) crossing of recipient antibodies with donor antigens (3) renal function to provide a CNI sparing regimen long term Some considerations for avoiding induction may include: (1) older age of the recipient (2) underlying comorbid conditions such as infections or frailty of the recipient What are expected activity restrictions post-transplant? Sternal precautions are important to maintain sternal wire integrity. Generally avoiding lifting >10 pounds in the first 4-12 weeks, no driving usually in the first 4 weeks, monitoring for signs and symptoms of wound infections, and optimizing nutrition and physical activity. Cardiac rehabilitation is incredibly important as soon as feasible. References Kharawala A , Nagraj S , Seo J , et al. Donation after circulatory death heart transplant: current state and future directions. Circ: Heart Failure. 2024;17(7). doi: 10.1161/circheartfailure.124.011678  Copeland H, Knezevic I, Baran DA, et al. Donor heart selection: Evidence-based guidelines for providers. The Journal of Heart and Lung Transplantation. 2023;42(1):7-29. doi:10.1016/j.healun.2022.08.030  Moayedifar R, Shudo Y, Kawabori M, et al. Recipient Outcomes With Extended Criteria Donors Using Advanced Heart Preservation: An Analysis of the GUARDIAN-Heart Registry. J Heart Lung Transplant. 2024;43(4):673-680. doi:10.1016/j.healun.2023.12.013  Kharawala A, Nagraj S, Seo J, et al. Donation After Circulatory Death Heart Transplant: Current State and Future Directions. Circ Heart Fail. 2024;17(7):e011678. doi:10.1161/CIRCHEARTFAILURE.124.011678  Copeland H, Hayanga JWA, Neyrinck A, et al. Donor heart and lung procurement: A consensus statement. J Heart Lung Transplant. 2020;39(6):501-517.

In hour two, stats from last night's game until Solana spills his coffee in the studio. Even Troy Aikman couldn't resist ripping Mike McDaniel and the Dolphins for their brutal clock management in the 4th quarter down 28-3.

At the end of every year, I like to take a step back and look at what's really happening in our industry. Not just at a surface level, but underneath it all. In this episode, I'm joined by my good friend Gordon Miller for one of our now-regular “state of the nation” conversations, where we dig into the biggest shifts shaping the hairdressing industry right now.We talk about the growing importance of data, what AI is actually being used for inside real salons, and why understanding the numbers is no longer optional if you want a sustainable, profitable business. Gordon shares practical examples of how salons are using AI to improve communication, training, productivity, and decision-making, not as a replacement for people, but as a tool to make people better at what they do.We also explore the changing relationship between salons and product companies, the rise of independent and freelance models, and why great commission-based salons are still creating incredible careers for hairdressers who want stability, structure, and serious earning potential. If you care about the future of this industry and your place in it, this is a conversation worth listening to.IN THIS EPISODE:[00:00] Welcome and introduction[00:24] Why end-of-year reflection matters for salon owners[02:14] The two biggest changes Gordon's seeing in 2025[03:02] Data is becoming the decoder ring for everything[04:23] What's driving the focus on numbers and KPIs[08:37] The AI revolution in hairdressing salons[10:17] Real use cases: How top salons are using AI daily[14:42] Using AI to improve manager-team member communication[17:05] The connection between data and AI in salons[18:13] How salon tech companies are integrating AI[21:24] The evolution of the salon business model[25:04] Why the commission model isn't going anywhere[31:02] The truth about working hours in the industry[36:40] The changing relationship between salons and manufacturers[42:24] Why salon associations matter more than ever[45:25] Where to connect with Gordon MillerWant MORE to help you GROW?

Eve gives an overview of current and future consumer trends where dairy can play a role. Functional foods, health and wellness, high protein foods, fermented and cultured foods, women's health, brain health, and aging are all part of the mix. (7:26)The panelists discuss the healthfulness of saturated fats, the resurgence of butter, milk's bioactive compounds, and how best to reach the public about the health benefits of dairy. (10:41)Eve talks about marketing to Gen Z consumers, who are motivated by novelty. How do we reimagine a food that's been here for thousands of years? What new ways can we talk about it? What ways can we optimize dairy science and research to show up in generative systems like ChatGPT? (20:34)The group then tackles the topic of lactose. Lactose and honey are the only two sugars not made by plants. Why is it lactose that is in the milk of mammals? Dr. Jiminez-Flores thinks lactose is a dark horse in dairy and we have much yet to discover about it. He notes that some milk oligosaccharides are not digested by babies, but are used by bacteria in the development of a healthy microbiome. Dr. Lucy notes that dairy also contains peptides that have been found to reduce hypertension. The group also delves into how dairy products can be part of preventative health care. (23:53)Do consumers perceive dairy products to be minimally processed? Eve explains that dairy is perceived as a clean, fresh food. Given the current trend to reduce additives and food dyes, she sees potential for dairy food science innovation in this area. Dr. Aldrich talks about the glycemic index of lactose-free milk. (38:13)The panelists agree that dairy has a great upcycling story to tell. Converting fiber into milk and meat and feeding non-human grade byproducts are just two examples. Eve notes that younger consumers care about sustainability, but there's a huge “say-do” gap: 76% of North American consumers identify as caring about conscious and sustainable practices, but less than 40% actually act on those values when making purchases. The panel also notes that whey is another great upcycling story. Dr. Jiminez-Flores emphasizes how important consumer trust in science and research is, and how we are currently experiencing a loss of that trust. (45:48)Panelists share their take-home thoughts. (1:01:01)Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

In Episode 3 of our hemolytic disease of the fetus and newborn (HDFN) series, host Paul Wirkus, MD, FAAP and guest Tim Bahr, MD, FAAP focus on clinical management and emerging consensus around care. Our discussion reviews key elements of the recently published consensus paper, including proposed guidelines for evaluation, monitoring, and treatment across the perinatal and neonatal periods. They address management of hyperbilirubinemia and anemia, escalation of care when disease severity increases, and the critical role of early recognition.We also explore high-risk presentations, including hydrops fetalis, and discuss delivery room considerations and coordination with Neonatal Resuscitation Program (NRP) protocols. Emphasis is placed on interdisciplinary collaboration between obstetrics, neonatology, hematology, and pediatrics to ensure timely intervention and continuity of care for affected infants.Have a question? Email questions@vcurb.com. They will be answered next week.For more information about available credit, visit vCurb.com.ACCME Accreditation StatementThis activity has been planned and implemented in accordance with the accreditation requirements and policies of the Colorado Medical Society through the joint providership of Kansas Chapter, American Academy of Pediatrics and Utah Chapter, AAP.  Kansas Chapter, American Academy of Pediatrics is accredited by the Colorado Medical Society to provide continuing medical education for physicians. AMA Credit Designation StatementKansas Chapter, American Academy of Pediatrics designates this live activity for a maximum of 1.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Can genomic classifiers close the gap between what we see and what a tumor will do? In this episode of BackTable Urology, Dr. Carissa Chu (UCSF) joins Dr. Ruchika Talwar (Vanderbilt) to explore how genomic classifiers are reshaping the way clinicians diagnose and manage bladder cancer. --- This podcast is supported by: VeracyteVeracyte.com/decipher-bladder --- SYNPOSIS They discuss the limitations of traditional staging systems and how molecular subtyping is providing deeper insight into tumor biology, treatment response, and prognosis. Dr. Chu highlights where these classifiers can be integrated into real-world clinical decision-making today, where the evidence is still emerging, and which ongoing trials may define the next era of precision medicine in urologic oncology. --- TIMESTAMPS 0:00 - Introduction3:01 - Overview of Genomic Classifiers9:34 - Risk Stratification15:22 - Current Evidence for Genomic Classifiers22:07 - Clinical Implications of Biomarkers27:23 - Ordering Genomic Classifiers33:46 - Future Directions37:57 - Final Takeaways --- RESOURCES Alignment of molecular subtypes across multiple bladder cancer subtyping classifiershttps://pubmed.ncbi.nlm.nih.gov/38480079/ GUSTO Trialhttps://fundingawards.nihr.ac.uk/award/NIHR128103

In this episode, Swamiji continues his discourse on Bhagavad Gita Chapter 7, Verse 9, Part 2, reflecting on how the laws of nature themselves point to the existence of a Divine lawmaker. He explains that while science discovers and applies these laws, it cannot account for their origin. The very presence of order in creation implies a Creator who designed it.  Swamiji illustrates this truth with striking examples:  Fish live their entire lives in water without drowning, while humans can drown in a pool—God has designed them differently.  Birds fly effortlessly because their bones are hollow, a design that even modern aviation studies to replicate.  Flamingos migrate instinctively to Siberia, a land they have never seen, guided by divine programming.  He emphasizes that if there are laws, there must be a law maker, and that law maker is God. The glory of God is so vast that saints and poets have admitted defeat in trying to describe it. Swamiji cites Homer's insight that even thousands of musicians playing for thousands of years could not complete the narration of God's glories. Similarly, Vedic literature describes Anant Shesh, the thousand-hooded serpent, endlessly singing God's praises since the beginning of creation, yet never reaching completion.  Quoting Vyasadev, Swamiji explains that anyone who thinks they can count God's virtues has a childish intellect—just as a child imagines the mountain or ocean to be “this big.” The infinite glories of God cannot be measured. Even St. Augustine realized this when a child told him it was impossible to fit the ocean into a hole, just as it was impossible to capture God's glories in a book.  This episode inspires listeners to recognize God's infinite greatness, trust in His plan, and surrender with faith and devotion. The narration closes with the reminder that God's glory is boundless, and His love for us is eternal.  About Swami Mukundananda: Swami Mukundananda is a renowned spiritual leader, Vedic scholar, Bhakti saint, best-selling author, and an international authority on the subject of mind management. He is the founder of the unique yogic system called JKYog. Swamiji holds distinguished degrees in Engineering and Management from two of India's most prestigious institutions—IIT and IIM. Having taken the renounced order of life (sanyas), he is the senior disciple of Jagadguru Shree Kripaluji Maharaj, and has been sharing Vedic wisdom across the globe for decades.  

  In this episode, Swamiji shares the inspiring story of Joni Eareckson Tada, who became a quadriplegic at 17 after a diving accident. Her journey from anger, depression, and suicidal thoughts to becoming an acclaimed author, artist, and founder of a global disability ministry illustrates the power of resilience. Joni explains that her secret lies in disciplining herself to give thanks in all circumstances — gratitude became her reflex reaction.  Swamiji connects this attitude to Krishna's wisdom in the Bhagavad Gita (5.1), where He teaches Arjun that yogis renounce attachment and perform actions with body, senses, mind, and intellect solely for purification. True success, Swamiji explains, is measured not by external achievements but by inner purification. Elevated yogis welcome adversity as opportunities to cleanse the heart, remaining equanimous in success and failure, fame and infamy, comfort and discomfort.  This teaching matters because it reframes setbacks as divine gifts for growth. By cultivating gratitude and focusing on purification, seekers can rise stronger from adversity, awaken their inner power, and progress steadily toward liberation.  About Swami Mukundananda: Swami Mukundananda is a renowned spiritual leader, Vedic scholar, Bhakti saint, best‑selling author, and an international authority on the subject of mind management. He is the founder of the unique yogic system called JKYog. Swamiji holds distinguished degrees in Engineering and Management from two of India's most prestigious institutions—IIT and IIM. Having taken the renounced order of life (sanyas), he is the senior disciple of Jagadguru Shree Kripaluji Maharaj, and has been sharing Vedic wisdom across the globe for decades.   

  In this episode, Swamiji explains how many of life's problems appear overwhelming not because of their actual size, but because of the size we give them in our own minds. He begins with humorous and revealing stories — like the Mensa members overcomplicating a simple salt‑and‑pepper mix‑up, and a cargo truck stuck under a bridge that was freed by a child's simple idea of letting air out of the tires.  Swamiji emphasizes that our brilliant minds often complicate what could be solved with simplicity. He urges seekers to pause and ask: Am I making this harder than it really is? Am I looking for a clever answer instead of the right one?  Drawing from the Bhagavad Gita (Chapter 16, Verse 1), Swamiji highlights saintly virtues such as fearlessness, purity of mind, steadfastness in spiritual knowledge, charity, and straightforwardness. He explains that true strength comes from reframing challenges — not making mountains out of molehills, but seeing difficulties as opportunities for growth.  Swamiji concludes with Krishna's practical formula:  Don't let the mind make problems bigger than they are.  Don't overthink into more stress.  Ask yourself, could it have been worse?  Always look for the simpler solution.  This teaching matters because it empowers seekers to live with clarity and peace, turning crises into manageable situations and cultivating divine virtues in everyday life.  About Swami Mukundananda: Swami Mukundananda is a renowned spiritual leader, Vedic scholar, Bhakti saint, best‑selling author, and an international authority on the subject of mind management. He is the founder of the unique yogic system called JKYog. Swamiji holds distinguished degrees in Engineering and Management from two of India's most prestigious institutions—IIT and IIM. Having taken the renounced order of life (sanyas), he is the senior disciple of Jagadguru Shree Kripaluji Maharaj, and has been sharing Vedic wisdom across the globe for decades. 

  In this episode, Swamiji explains Krishna's teaching on the extraordinary power of the human mind and how it can be harnessed to overcome even the most difficult challenges. Drawing from the Bhagavad Gita, he emphasizes that setbacks are inevitable in life, but they need not defeat us if we cultivate the right mental attitude.  Swamiji shares real‑life stories and scriptural insights to show how resilience, determination, and faith transform obstacles into opportunities. He explains that the mind, when disciplined and aligned with dharma, becomes our greatest ally. Krishna assures that those who dedicate their thoughts and actions to Him gain inner strength that allows them to rise above adversity.  Through practical guidance, Swamiji highlights how to train the mind:  Replace negative self‑talk with positive, God‑centered thoughts.  Focus on effort rather than obsessing over results.  Practice meditation and devotion to anchor the mind in higher purpose.  Listeners are encouraged to see setbacks as divine training, cultivating patience and perseverance. This teaching matters because it empowers seekers to live courageously, transform failures into stepping stones, and progress steadily toward liberation.  About Swami Mukundananda: Swami Mukundananda is a renowned spiritual leader, Vedic scholar, Bhakti saint, best‑selling author, and an international authority on the subject of mind management. He is the founder of the unique yogic system called JKYog. Swamiji holds distinguished degrees in Engineering and Management from two of India's most prestigious institutions—IIT and IIM. Having taken the renounced order of life (sanyas), he is the senior disciple of Jagadguru Shree Kripaluji Maharaj, and has been sharing Vedic wisdom across the globe for decades.  

  In this fourth episode of the Narad Bhakti Sutra series, Swami Mukundananda narrates the astonishing story of Shree Bihari Ji in Vrindavan, where the Lord Himself appeared in court to testify for His devotee. This miracle reveals that deity worship is not about stone or ritual — it is a living connection with God when performed with sincerity.  Swamiji emphasizes that what truly counts in devotion is bhav — the heartfelt sentiment of love for Krishna. He explains how saints and devotees across ages have experienced divine reciprocation through idols and sacred forms, because the Lord is all‑pervading and responds to genuine love. Even Krishna's cowherd friends and the gopis, who addressed Him playfully as “Kana” or even “lungar” (loafer), attained the highest spiritual states through their pure affection.  For seekers, this episode highlights that devotion is not about external form but inner sincerity. By cultivating pure bhav in deity worship, one can experience Krishna's living presence, divine miracles, and ultimately liberation through His boundless grace.  About Swami Mukundananda: Swami Mukundananda is a renowned spiritual leader, Vedic scholar, Bhakti saint, best‑selling author, and an international authority on the subject of mind management. He is the founder of the unique yogic system called JKYog. Swamiji holds distinguished degrees in Engineering and Management from two of India's most prestigious institutions—IIT and IIM. Having taken the renounced order of life (sanyas), he is the senior disciple of Jagadguru Shree Kripaluji Maharaj, and has been sharing Vedic wisdom across the globe for decades. 

  In this episode, Swamiji begins his discourse on Bhagavad Gita Chapter 7, Verse 9, Part 1, where Shree Krishna declares: “Know that I am the eternal seed of all beings. I am the intelligence of the intelligent, and the prowess of the powerful, devoid of desire and attachment.” This verse reveals how God is the origin of vitality, wisdom, and strength in creation.  Swamiji explains that the seed principle represents God as the cause behind all living beings, sustaining their existence and growth. He highlights how true strength is not rooted in ego or desire but flows from the Divine when aligned with purity and detachment. Through vivid examples and scriptural clarity, listeners are guided to recognize that every ability—whether intellectual brilliance or physical power—ultimately originates from God.  This episode marks the beginning of a new arc in Chapter 7, inviting seekers to reflect on the Divine as the source of all potency and intelligence, and to cultivate humility by acknowledging God's role in their talents and achievements.  About Swami Mukundananda: Swami Mukundananda is a renowned spiritual leader, Vedic scholar, Bhakti saint, best-selling author, and an international authority on the subject of mind management. He is the founder of the unique yogic system called JKYog. Swamiji holds distinguished degrees in Engineering and Management from two of India's most prestigious institutions—IIT and IIM. Having taken the renounced order of life (sanyas), he is the senior disciple of Jagadguru Shree Kripaluji Maharaj, and has been sharing Vedic wisdom across the globe for decades.  

  In this episode, Swamiji begins his discourse on Bhagavad Gita Chapter 7, Verse 10, Part 1, where Shree Krishna declares: “I am the eternal seed of all beings. I am the intellect of the intelligent, and the splendor of the glorious.” This verse reveals how God is the cause behind all creation and the source of brilliance in human beings.  Swamiji explains that just as a seed contains the potential for a tree, God is the seed of all beings, the ultimate cause from which everything emanates. He emphasizes that intelligence and brilliance are not self-generated but bestowed by the Divine. Saints like Tulsidas admitted they were merely instruments, with God working through them to produce astonishing scriptures like the Ramcharitmanas. Similarly, the Bible affirms that holy men spoke as they were moved by the Spirit.  Swamiji illustrates this truth with vivid examples:  Bill Gates was empowered to create Windows, a common operating system, solving global interface problems—God chose him for that role.  Swami Vivekananda explained that even the British Empire, despite its faults, served God's purpose of uniting the world under a common language.  Tulsi Das revealed how Lord Ram Himself was the true doer behind his writings, showing that divine power manifests through chosen instruments.  Even humorous anecdotes, like the Gujarati millionaire cleverly using a bank loan for cheap parking, highlight how intelligence manifests in surprising ways—all ultimately sourced from God.  Swamiji concludes that whether brilliance or folly, all abilities originate from God. Recognizing this truth inspires humility, gratitude, and devotion, reminding seekers that they are instruments of the Divine.  About Swami Mukundananda: Swami Mukundananda is a renowned spiritual leader, Vedic scholar, Bhakti saint, best-selling author, and an international authority on the subject of mind management. He is the founder of the unique yogic system called JKYog. Swamiji holds distinguished degrees in Engineering and Management from two of India's most prestigious institutions—IIT and IIM. Having taken the renounced order of life (sanyas), he is the senior disciple of Jagadguru Shree Kripaluji Maharaj, and has been sharing Vedic wisdom across the globe for decades.